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Search of human proteins with 239752604
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239752604 PREDICTED: similar to immunoglobulin lambda-like
polypeptide 1 [Homo sapiens]
(490 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239752604 PREDICTED: similar to immunoglobulin lambda-like po... 1026 0.0
gi|239750731 PREDICTED: hypothetical protein XP_002347518, parti... 138 1e-32
gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo ... 68 2e-11
gi|239750729 PREDICTED: hypothetical protein XP_002347517 [Homo ... 67 3e-11
gi|13399298 immunoglobulin lambda-like polypeptide 1 isoform a p... 66 8e-11
gi|61966693 immunoglobulin lambda-like polypeptide 3 [Homo sapiens] 61 2e-09
gi|94538335 signal-regulatory protein gamma isoform 1 precursor ... 56 8e-08
gi|144953876 signal-regulatory protein beta 1 isoform 1 precurso... 55 1e-07
gi|239758095 PREDICTED: similar to major histocompatibility comp... 54 2e-07
gi|239740749 PREDICTED: similar to major histocompatibility comp... 54 2e-07
gi|18426911 signal-regulatory protein alpha precursor [Homo sapi... 53 5e-07
gi|91105767 signal-regulatory protein alpha precursor [Homo sapi... 53 5e-07
gi|91105764 signal-regulatory protein alpha precursor [Homo sapi... 53 5e-07
gi|209529703 signal-regulatory protein beta 1 isoform 3 precurso... 53 5e-07
gi|239740920 PREDICTED: similar to major histocompatibility comp... 53 7e-07
gi|239740918 PREDICTED: similar to major histocompatibility comp... 53 7e-07
gi|169168591 PREDICTED: similar to major histocompatibility comp... 52 2e-06
gi|239748788 PREDICTED: similar to major histocompatibility comp... 52 2e-06
gi|239740863 PREDICTED: similar to major histocompatibility comp... 52 2e-06
gi|239513955 PREDICTED: similar to major histocompatibility comp... 52 2e-06
gi|150418002 major histocompatibility complex, class II, DQ beta... 50 4e-06
gi|4504403 major histocompatibility complex, class II, DO beta p... 50 4e-06
gi|94538339 signal-regulatory protein gamma isoform 3 precursor ... 45 1e-04
gi|52630344 major histocompatibility complex, class II, DR beta ... 45 1e-04
gi|239758090 PREDICTED: major histocompatibility complex, class ... 45 1e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 45 2e-04
gi|24797076 major histocompatibility complex, class II, DP beta ... 45 2e-04
gi|155030211 major histocompatibility complex, class II, DR beta... 45 2e-04
gi|169217452 PREDICTED: similar to HLA class II histocompatibili... 45 2e-04
gi|17986005 major histocompatibility complex, class II, DR beta ... 44 3e-04
>gi|239752604 PREDICTED: similar to immunoglobulin lambda-like
polypeptide 1 [Homo sapiens]
Length = 490
Score = 1026 bits (2652), Expect = 0.0
Identities = 490/490 (100%), Positives = 490/490 (100%)
Query: 1 MASGRWANRVQPLELGTRAEQRQVSTGWWEAGGTGGSSGTSGDQGRASEGEQGLVGAGRA 60
MASGRWANRVQPLELGTRAEQRQVSTGWWEAGGTGGSSGTSGDQGRASEGEQGLVGAGRA
Sbjct: 1 MASGRWANRVQPLELGTRAEQRQVSTGWWEAGGTGGSSGTSGDQGRASEGEQGLVGAGRA 60
Query: 61 GGSPWSSGDQGRAATGEQGLVGSRRSRGQPLELRAPGQSTLSWLWGREWAKVRQVAPARC 120
GGSPWSSGDQGRAATGEQGLVGSRRSRGQPLELRAPGQSTLSWLWGREWAKVRQVAPARC
Sbjct: 61 GGSPWSSGDQGRAATGEQGLVGSRRSRGQPLELRAPGQSTLSWLWGREWAKVRQVAPARC 120
Query: 121 TPNAREPRHWTLPGPSWIDKNRGASAPWAQLCPTPRSHGTTSLAASTKGPSVFPLAPCSR 180
TPNAREPRHWTLPGPSWIDKNRGASAPWAQLCPTPRSHGTTSLAASTKGPSVFPLAPCSR
Sbjct: 121 TPNAREPRHWTLPGPSWIDKNRGASAPWAQLCPTPRSHGTTSLAASTKGPSVFPLAPCSR 180
Query: 181 STSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNF 240
STSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNF
Sbjct: 181 STSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNF 240
Query: 241 GTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTP 300
GTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTP
Sbjct: 241 GTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTP 300
Query: 301 EVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGK 360
EVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGK
Sbjct: 301 EVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGK 360
Query: 361 EYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDI 420
EYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDI
Sbjct: 361 EYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDI 420
Query: 421 AVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
AVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT
Sbjct: 421 AVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
Query: 481 QKSLSLSPGK 490
QKSLSLSPGK
Sbjct: 481 QKSLSLSPGK 490
>gi|239750731 PREDICTED: hypothetical protein XP_002347518, partial
[Homo sapiens]
Length = 214
Score = 138 bits (347), Expect = 1e-32
Identities = 73/214 (34%), Positives = 119/214 (55%), Gaps = 4/214 (1%)
Query: 280 GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTKPREEQF 339
G S +L P P D L I ++P +TC+VVD++ V W + N T+ E+Q
Sbjct: 2 GVSAYLSRPSPFD-LFIRKSPTITCLVVDLAPSKWTVNLTWSRASGKPVNHSTRKEEKQR 60
Query: 340 NSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSRE 399
N T V S L V +DW+ G+ Y+C+V++ LP + ++ +KT G P+VY
Sbjct: 61 NGTLTVTSTLPVGTRDWIEGETYQCRVTHPHLPRALVRSTTKTSGPRAAPEVYAFATPEW 120
Query: 400 EMTKNQVSLTCLVKGFYPSDIAVEWESN--GQPENNYKTTPPMLDSDGSFFLYSKLTVDK 457
++++ +LTCL++ F P DI+V+W N P+ + TT P FF++S+L V +
Sbjct: 121 LGSRDKRTLTCLIQNFMPEDISVQWLHNEVQLPDAQHSTTQPRKTKGSGFFIFSRLEVTR 180
Query: 458 SRWQQGNVFSCSVMHEALHNHYT-QKSLSLSPGK 490
+ W+Q + F C +HEA T Q+++S++PGK
Sbjct: 181 AEWEQKDEFICRAVHEAASPSQTVQRAVSVNPGK 214
Score = 37.4 bits (85), Expect = 0.031
Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 18/186 (9%)
Query: 95 APGQSTLSWLWGREWAKVRQVAPARCTPNAREPRHWTLPGPS--------WIDKNRGASA 146
AP + T++ W R K T + R+ TL S WI+
Sbjct: 31 APSKWTVNLTWSRASGKPVN----HSTRKEEKQRNGTLTVTSTLPVGTRDWIEGETYQCR 86
Query: 147 PWAQLCPTPRSHGTTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW- 205
P TT + P V+ A S L CL++++ PE ++V W
Sbjct: 87 VTHPHLPRALVRSTTKTSGPRAAPEVYAFATPEWLGSRDKRTLTCLIQNFMPEDISVQWL 146
Query: 206 -NSGALTSGVH--TFPAVLQSSGLYSLSSVVTVTSSNFGTQTYTCNVDHKPSNTKVDKTV 262
N L H T P + SG + S + + + C H+ ++ +TV
Sbjct: 147 HNEVQLPDAQHSTTQPRKTKGSGFFIFSRLEVTRAEWEQKDEFICRAVHEAASP--SQTV 204
Query: 263 ERKCCV 268
+R V
Sbjct: 205 QRAVSV 210
>gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo
sapiens]
Length = 264
Score = 67.8 bits (164), Expect = 2e-11
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 384 GQPRE-PQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQP-ENNYKTTPPML 441
GQP+ P V PPS EE+ N+ +L CL+ FYP + V W+++ P + +TT P
Sbjct: 159 GQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSK 218
Query: 442 DSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE 473
S+ + S L++ +W+ +SC V HE
Sbjct: 219 QSNNKYAASSYLSLTPEQWKSHRSYSCQVTHE 250
Score = 58.2 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 161 TSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW--NSGALTSGVHTFP 218
T L PSV P S + A L CL+ D++P VTV+W +S + +GV T
Sbjct: 156 TVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTT 215
Query: 219 AVLQSSGLYSLSSVVTVTSSNFGT-QTYTCNVDHKPSNTKVDKTVERKCC 267
QS+ Y+ SS +++T + + ++Y+C V H+ S V+KTV C
Sbjct: 216 PSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGST--VEKTVAPTEC 263
Score = 46.6 bits (109), Expect = 5e-05
Identities = 30/108 (27%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Query: 277 PVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEVH-NAKTKPR 335
P A PSV LFPP ++ T + C++ D V W D V +T
Sbjct: 161 PKAAPSVTLFPPSSEELQANKAT--LVCLISDFY--PGAVTVAWKADSSPVKAGVETTTP 216
Query: 336 EEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTK 383
+Q N+ + S L++ + W + + Y C+V+++G + +EKT++ T+
Sbjct: 217 SKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEG--STVEKTVAPTE 262
>gi|239750729 PREDICTED: hypothetical protein XP_002347517 [Homo
sapiens]
Length = 263
Score = 67.4 bits (163), Expect = 3e-11
Identities = 61/202 (30%), Positives = 94/202 (46%), Gaps = 22/202 (10%)
Query: 125 REPRH-WT--LPGPSWIDKNRGASAPWAQLCPTPRSHGTTSLAASTKGPSVFPLAPCSRS 181
R PRH W PGP+ + G+ QL P + + AS P VFPL+ S +
Sbjct: 52 RAPRHSWPPPTPGPASL---AGSLQRNGQLSGDPHAF---CVPASPTSPKVFPLSLDS-T 104
Query: 182 TSESTAALGCLVKDYFP-EPVTVSWNSGALTSGVHTFPAVLQSSG-LYSLSSVVTVTSSN 239
+ + CLV+ +FP EP++V+W+ FP +SG LY+ SS +T+ ++
Sbjct: 105 PQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQ 164
Query: 240 FGT-QTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISR 298
++ TC+V H +N D TV CP P PP P + L P +D L++S
Sbjct: 165 CPDGKSVTCHVKHY-TNPSQDVTVP------CPVPPPPPCCHPRLSLHRPALED-LLLSS 216
Query: 299 TPEVTCVVVDVSHEDPEVQFNW 320
+TC + + + F W
Sbjct: 217 EANLTCTLTGL-RDASGATFTW 237
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Query: 386 PREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSD-IAVEWESNGQPENNYKTTPPMLDSD 444
P P+V+ L N V + CLV+GF+P + ++V W +GQ + PP D+
Sbjct: 91 PTSPKVFPLSLDSTPQDGNVV-VACLVQGFFPQEPLSVTWSESGQ-NVTARNFPPSQDAS 148
Query: 445 GSFF-LYSKLTVDKSRWQQGNVFSCSVMH 472
G + S+LT+ ++ G +C V H
Sbjct: 149 GDLYTTSSQLTLPATQCPDGKSVTCHVKH 177
>gi|13399298 immunoglobulin lambda-like polypeptide 1 isoform a
precursor [Homo sapiens]
Length = 213
Score = 65.9 bits (159), Expect = 8e-11
Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 2/91 (2%)
Query: 385 QPRE-PQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQP-ENNYKTTPPMLD 442
QP+ P V PPS EE+ N+ +L CL+ FYP + V W+++G P + T P
Sbjct: 109 QPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQ 168
Query: 443 SDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE 473
S+ + S L++ +W+ +SC VMHE
Sbjct: 169 SNNKYAASSYLSLTPEQWRSRRSYSCQVMHE 199
Score = 56.2 bits (134), Expect = 6e-08
Identities = 62/231 (26%), Positives = 93/231 (40%), Gaps = 29/231 (12%)
Query: 46 RASEGEQGLVGAGRAGGS---PWSSGDQGRAATGEQGLVGSRRSRGQPLELRAPGQSTLS 102
R G+ GL G G + W G A L + S+ + L APG S+ S
Sbjct: 2 RPGTGQGGLEAPGEPGPNLRQRWPLLLLGLAVVTHGLLRPTAASQSRALGPGAPGGSSRS 61
Query: 103 WL---WGREWAKVRQVAPARCTPNAREPRHWTLPGPSWIDKNRGASAPWAQLCPTPRSHG 159
L WGR + RC P + +H ++ QL
Sbjct: 62 SLRSRWGRFLLQRGSWTGPRCWPRGFQSKHNSVTH---------VFGSGTQL-------- 104
Query: 160 TTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGA--LTSGVHTF 217
T L+ PSV P S + A L CL+ D++P +TV+W + +T GV
Sbjct: 105 -TVLSQPKATPSVTLFPPSSEELQANKATLVCLMNDFYPGILTVTWKADGTPITQGVEMT 163
Query: 218 PAVLQSSGLYSLSSVVTVTSSNF-GTQTYTCNVDHKPSNTKVDKTVERKCC 267
QS+ Y+ SS +++T + ++Y+C V H+ S V+KTV C
Sbjct: 164 TPSKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEGST--VEKTVAPAEC 212
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
Query: 277 PVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEV-HNAKTKPR 335
P A PSV LFPP ++ T + C++ D V W DG + +
Sbjct: 110 PKATPSVTLFPPSSEELQANKAT--LVCLMNDFYPGILTV--TWKADGTPITQGVEMTTP 165
Query: 336 EEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTIS 380
+Q N+ + S L++ + W + + Y C+V ++G + +EKT++
Sbjct: 166 SKQSNNKYAASSYLSLTPEQWRSRRSYSCQVMHEG--STVEKTVA 208
>gi|61966693 immunoglobulin lambda-like polypeptide 3 [Homo sapiens]
Length = 224
Score = 61.2 bits (147), Expect = 2e-09
Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 384 GQPRE-PQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQP-ENNYKTTPPML 441
GQP+ P V PS EE+ N+ +L CL+ FY + V W+++G P + T P
Sbjct: 119 GQPKATPSVTLFLPSSEELQANKATLVCLMNDFYLGILTVTWKADGTPITQGVEMTTPSK 178
Query: 442 DSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE 473
S+ + S L++ +W+ +SC VMHE
Sbjct: 179 QSNSKYMASSYLSLTPEQWRSRRSYSCQVMHE 210
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 9/158 (5%)
Query: 117 PARCTPNAREPRHWTLPGPSWIDKN---RGASAPWAQLCPTPRSHGTTSLAASTKG-PSV 172
P C+P P + L SW RG + + S ++ K PSV
Sbjct: 68 PTHCSPVPLTPSRFLLQRGSWTGPGCWPRGFQSKHNSVKHVFGSGTQLTVLGQPKATPSV 127
Query: 173 FPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGA--LTSGVHTFPAVLQSSGLYSLS 230
P S + A L CL+ D++ +TV+W + +T GV QS+ Y S
Sbjct: 128 TLFLPSSEELQANKATLVCLMNDFYLGILTVTWKADGTPITQGVEMTTPSKQSNSKYMAS 187
Query: 231 SVVTVTSSNF-GTQTYTCNVDHKPSNTKVDKTVERKCC 267
S +++T + ++Y+C V H+ S +KTV C
Sbjct: 188 SYLSLTPEQWRSRRSYSCQVMHEGST--AEKTVAPAEC 223
Score = 37.0 bits (84), Expect = 0.041
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
Query: 277 PVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEV-HNAKTKPR 335
P A PSV LF P ++ T + C++ D V W DG + +
Sbjct: 121 PKATPSVTLFLPSSEELQANKAT--LVCLMNDFYLGILTV--TWKADGTPITQGVEMTTP 176
Query: 336 EEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTIS 380
+Q NS + S L++ + W + + Y C+V ++G A EKT++
Sbjct: 177 SKQSNSKYMASSYLSLTPEQWRSRRSYSCQVMHEGSTA--EKTVA 219
>gi|94538335 signal-regulatory protein gamma isoform 1 precursor
[Homo sapiens]
Length = 387
Score = 55.8 bits (133), Expect = 8e-08
Identities = 58/246 (23%), Positives = 100/246 (40%), Gaps = 21/246 (8%)
Query: 232 VVTVTSSNFGTQTYTCNVDHK--PSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPK 289
+ ++T ++ GT Y C K P N + + + P AP V GP+ P
Sbjct: 106 ISSITPADVGT--YYCVKFRKGSPENVEFKSGPGTEMALGAKPS-APVVLGPAARTTP-- 160
Query: 290 PKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTKPREEQFNSTFRVVSVL 349
T TC S D + W+ +G E+ + +T + + + S
Sbjct: 161 -------EHTVSFTCESHGFSPRD--ITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTA 211
Query: 350 TVVHQDWLNGKEYKCKVSNKGLPA-PIEKTISKTKGQPREPQVYTLPPSREEM-TKNQVS 407
VV W + C+V++ L P+ T + ++ P TL +++ M NQV+
Sbjct: 212 RVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPP---TLEVTQQPMRVGNQVN 268
Query: 408 LTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFS 467
+TC V+ FYP + + W NG + + DG++ S V+ S + V +
Sbjct: 269 VTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNWTSWFLVNISDQRDDVVLT 328
Query: 468 CSVMHE 473
C V H+
Sbjct: 329 CQVKHD 334
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T +P P V L P+ ++ VS TC GF
Sbjct: 117 YYCVKFRKGSPENVEFKSGPGTEMALGAKPSAPVV--LGPAARTTPEHTVSFTCESHGFS 174
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T ++ + S V W + C V H L
Sbjct: 175 PRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQ 234
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 235 GDPLRGTANLS 245
Score = 33.1 bits (74), Expect = 0.59
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 161 TSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW-NSGALTSGVHTFPA 219
T +A K + L P +R+T E T + C + P +T+ W +G S T
Sbjct: 138 TEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVD 197
Query: 220 VLQSSGLYSLSSVVTVTSSNFGTQTYT-CNVDH 251
S YS+ S V + ++ C V H
Sbjct: 198 PTGQSVAYSIRSTARVVLDPWDVRSQVICEVAH 230
>gi|144953876 signal-regulatory protein beta 1 isoform 1 precursor
[Homo sapiens]
Length = 398
Score = 55.1 bits (131), Expect = 1e-07
Identities = 63/253 (24%), Positives = 103/253 (40%), Gaps = 33/253 (13%)
Query: 231 SVVTVTSSNFGTQTYTCNVDHK--PSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPP 288
S+ +T ++ GT Y C K P + + + V P AP V+GP+V P
Sbjct: 106 SISNITPADAGT--YYCVKFRKGSPDDVEFKSGAGTELSVRAKPS-APVVSGPAVRATP- 161
Query: 289 KPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTK--PREEQ----FNST 342
T TC S D + W+ +G E+ + +T P + +ST
Sbjct: 162 --------EHTVSFTCESHGFSPRD--ITLKWFKNGNELSDFQTNVDPAGDSVSYSIHST 211
Query: 343 FRVVSVLTVVHQDWLNGKEYKCKVSNKGLPA-PIEKTISKTKGQPREPQV-YTLPPSREE 400
RVV VH + C++++ L P+ T + ++ P + T P R E
Sbjct: 212 ARVVLTRGDVHSQVI------CEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAE 265
Query: 401 MTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRW 460
NQ ++TC V FYP + + W NG + + + DG++ S L V+
Sbjct: 266 ---NQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAH 322
Query: 461 QQGNVFSCSVMHE 473
+ V +C V H+
Sbjct: 323 RDDVVLTCQVEHD 335
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T + +P P V P+ ++ VS TC GF
Sbjct: 118 YYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSG--PAVRATPEHTVSFTCESHGFS 175
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T S+ ++S V +R + C + H L
Sbjct: 176 PRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQ 235
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 236 GDPLRGTANLS 246
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 159 GTTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFP 218
GT +L+ + + P + +E+ A + C V +++P + ++W S T
Sbjct: 241 GTANLSEAIRVPPTLEVTQ-QPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETAS 299
Query: 219 AVLQS-SGLYS-LSSVVTVTSSNFGTQTYTCNVDH 251
++++ G Y+ +S ++ T ++ TC V+H
Sbjct: 300 TLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEH 334
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W NGQ E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + D +F + L + Q+G+V++C V H +L + T
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|239740749 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W NGQ E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + D +F + L + Q+G+V++C V H +L + T
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|18426911 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 53.1 bits (126), Expect = 5e-07
Identities = 63/241 (26%), Positives = 97/241 (40%), Gaps = 33/241 (13%)
Query: 244 TYTCNVDHK--PSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPE 301
TY C K P + + + V P AP V+GP+ P T
Sbjct: 118 TYYCVKFRKGSPDDVEFKSGAGTELSVRAKPS-APVVSGPAARATP---------QHTVS 167
Query: 302 VTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTK--PREEQ----FNSTFRVVSVLTVVHQD 355
TC S D + W+ +G E+ + +T P E +ST +VV VH
Sbjct: 168 FTCESHGFSPRD--ITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQ 225
Query: 356 WLNGKEYKCKVSN---KGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLV 412
+ C+V++ +G P +S+T P +V T P R E NQV++TC V
Sbjct: 226 VI------CEVAHVTLQGDPLRGTANLSETIRVPPTLEV-TQQPVRAE---NQVNVTCQV 275
Query: 413 KGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMH 472
+ FYP + + W NG + + DG++ S L V+ S + +C V H
Sbjct: 276 RKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEH 335
Query: 473 E 473
+
Sbjct: 336 D 336
Score = 46.2 bits (108), Expect = 7e-05
Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T + +P P V P+ ++ VS TC GF
Sbjct: 119 YYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSG--PAARATPQHTVSFTCESHGFS 176
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T + S+ ++S V +R + C V H L
Sbjct: 177 PRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQ 236
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 237 GDPLRGTANLS 247
Score = 35.0 bits (79), Expect = 0.15
Identities = 49/241 (20%), Positives = 82/241 (34%), Gaps = 28/241 (11%)
Query: 156 RSHGTTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW-NSGALTSGV 214
+S T L+ K + P +R+T + T + C + P +T+ W +G S
Sbjct: 135 KSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDF 194
Query: 215 HTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCP 274
T + S YS+ S V T+ D + C V
Sbjct: 195 QTNVDPVGESVSYSIHSTAKVVL------------------TREDVHSQVICEVAHVTLQ 236
Query: 275 APPVAGPSVFLFPPKPKDTLMISRTP-------EVTCVVVDVSHEDPEVQFNWYVDGMEV 327
P+ G + + TL +++ P VTC V + +Q W +G
Sbjct: 237 GDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQ--RLQLTWLENGNVS 294
Query: 328 HNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPR 387
E + T+ +S L V + + C+V + G PA + K P+
Sbjct: 295 RTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPK 354
Query: 388 E 388
E
Sbjct: 355 E 355
>gi|91105767 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 53.1 bits (126), Expect = 5e-07
Identities = 63/241 (26%), Positives = 97/241 (40%), Gaps = 33/241 (13%)
Query: 244 TYTCNVDHK--PSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPE 301
TY C K P + + + V P AP V+GP+ P T
Sbjct: 118 TYYCVKFRKGSPDDVEFKSGAGTELSVRAKPS-APVVSGPAARATP---------QHTVS 167
Query: 302 VTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTK--PREEQ----FNSTFRVVSVLTVVHQD 355
TC S D + W+ +G E+ + +T P E +ST +VV VH
Sbjct: 168 FTCESHGFSPRD--ITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQ 225
Query: 356 WLNGKEYKCKVSN---KGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLV 412
+ C+V++ +G P +S+T P +V T P R E NQV++TC V
Sbjct: 226 VI------CEVAHVTLQGDPLRGTANLSETIRVPPTLEV-TQQPVRAE---NQVNVTCQV 275
Query: 413 KGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMH 472
+ FYP + + W NG + + DG++ S L V+ S + +C V H
Sbjct: 276 RKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEH 335
Query: 473 E 473
+
Sbjct: 336 D 336
Score = 46.2 bits (108), Expect = 7e-05
Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T + +P P V P+ ++ VS TC GF
Sbjct: 119 YYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSG--PAARATPQHTVSFTCESHGFS 176
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T + S+ ++S V +R + C V H L
Sbjct: 177 PRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQ 236
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 237 GDPLRGTANLS 247
Score = 35.0 bits (79), Expect = 0.15
Identities = 49/241 (20%), Positives = 82/241 (34%), Gaps = 28/241 (11%)
Query: 156 RSHGTTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW-NSGALTSGV 214
+S T L+ K + P +R+T + T + C + P +T+ W +G S
Sbjct: 135 KSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDF 194
Query: 215 HTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCP 274
T + S YS+ S V T+ D + C V
Sbjct: 195 QTNVDPVGESVSYSIHSTAKVVL------------------TREDVHSQVICEVAHVTLQ 236
Query: 275 APPVAGPSVFLFPPKPKDTLMISRTP-------EVTCVVVDVSHEDPEVQFNWYVDGMEV 327
P+ G + + TL +++ P VTC V + +Q W +G
Sbjct: 237 GDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQ--RLQLTWLENGNVS 294
Query: 328 HNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPR 387
E + T+ +S L V + + C+V + G PA + K P+
Sbjct: 295 RTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPK 354
Query: 388 E 388
E
Sbjct: 355 E 355
>gi|91105764 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 53.1 bits (126), Expect = 5e-07
Identities = 63/241 (26%), Positives = 97/241 (40%), Gaps = 33/241 (13%)
Query: 244 TYTCNVDHK--PSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPE 301
TY C K P + + + V P AP V+GP+ P T
Sbjct: 118 TYYCVKFRKGSPDDVEFKSGAGTELSVRAKPS-APVVSGPAARATP---------QHTVS 167
Query: 302 VTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTK--PREEQ----FNSTFRVVSVLTVVHQD 355
TC S D + W+ +G E+ + +T P E +ST +VV VH
Sbjct: 168 FTCESHGFSPRD--ITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQ 225
Query: 356 WLNGKEYKCKVSN---KGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLV 412
+ C+V++ +G P +S+T P +V T P R E NQV++TC V
Sbjct: 226 VI------CEVAHVTLQGDPLRGTANLSETIRVPPTLEV-TQQPVRAE---NQVNVTCQV 275
Query: 413 KGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMH 472
+ FYP + + W NG + + DG++ S L V+ S + +C V H
Sbjct: 276 RKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEH 335
Query: 473 E 473
+
Sbjct: 336 D 336
Score = 46.2 bits (108), Expect = 7e-05
Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T + +P P V P+ ++ VS TC GF
Sbjct: 119 YYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSG--PAARATPQHTVSFTCESHGFS 176
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T + S+ ++S V +R + C V H L
Sbjct: 177 PRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQ 236
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 237 GDPLRGTANLS 247
Score = 35.0 bits (79), Expect = 0.15
Identities = 49/241 (20%), Positives = 82/241 (34%), Gaps = 28/241 (11%)
Query: 156 RSHGTTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW-NSGALTSGV 214
+S T L+ K + P +R+T + T + C + P +T+ W +G S
Sbjct: 135 KSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDF 194
Query: 215 HTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCP 274
T + S YS+ S V T+ D + C V
Sbjct: 195 QTNVDPVGESVSYSIHSTAKVVL------------------TREDVHSQVICEVAHVTLQ 236
Query: 275 APPVAGPSVFLFPPKPKDTLMISRTP-------EVTCVVVDVSHEDPEVQFNWYVDGMEV 327
P+ G + + TL +++ P VTC V + +Q W +G
Sbjct: 237 GDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQ--RLQLTWLENGNVS 294
Query: 328 HNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPR 387
E + T+ +S L V + + C+V + G PA + K P+
Sbjct: 295 RTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPK 354
Query: 388 E 388
E
Sbjct: 355 E 355
>gi|209529703 signal-regulatory protein beta 1 isoform 3 precursor
[Homo sapiens]
Length = 398
Score = 53.1 bits (126), Expect = 5e-07
Identities = 83/337 (24%), Positives = 129/337 (38%), Gaps = 50/337 (14%)
Query: 161 TSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGA-------LTSG 213
T +A + + P S + ES A L C V P + W GA
Sbjct: 25 TGVAGEEELQVIQPDKSISVAAGES-ATLHCTVTSLIPVG-PIQWFRGAGPGRELIYNQK 82
Query: 214 VHTFPAVLQSSGLYSLSS------VVTVTSSNFGTQTYTCNVDHK--PSNTKVDKTVERK 265
FP V S L ++ + +T ++ GT Y C K P + + +
Sbjct: 83 EGHFPRVTTVSDLTKRNNMDFSIRISNITPADAGT--YYCVKFRKGSPDHVEFKSGAGTE 140
Query: 266 CCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGM 325
V P AP V+GP+ P T TC S D + W+ +G
Sbjct: 141 LSVRAKPS-APVVSGPAARATP---------QHTVSFTCESHGFSPRD--ITLKWFKNGN 188
Query: 326 EVHNAKTK--PREEQ----FNSTFRVVSVLTVVHQDWLNGKEYKCKVSN---KGLPAPIE 376
E+ + +T P + +ST +VV VH + C+V++ +G P
Sbjct: 189 ELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVI------CEVAHVTLQGDPLRGT 242
Query: 377 KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKT 436
+S+T P +V T P R E NQV++TC V+ FYP + + W NG
Sbjct: 243 ANLSETIRVPPTLEV-TQQPVRAE---NQVNVTCQVRKFYPQRLQLTWLENGNVSRTETA 298
Query: 437 TPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE 473
+ + DG++ S L V+ S + +C V H+
Sbjct: 299 STLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHD 335
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T + +P P V P+ ++ VS TC GF
Sbjct: 118 YYCVKFRKGSPDHVEFKSGAGTELSVRAKPSAPVVSG--PAARATPQHTVSFTCESHGFS 175
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T S+ ++S V +R + C V H L
Sbjct: 176 PRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQ 235
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 236 GDPLRGTANLS 246
Score = 36.2 bits (82), Expect = 0.070
Identities = 51/248 (20%), Positives = 83/248 (33%), Gaps = 28/248 (11%)
Query: 156 RSHGTTSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW-NSGALTSGV 214
+S T L+ K + P +R+T + T + C + P +T+ W +G S
Sbjct: 134 KSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDF 193
Query: 215 HTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCP 274
T S YS+ S V T+ D + C V
Sbjct: 194 QTNVDPAGDSVSYSIHSTAKVVL------------------TREDVHSQVICEVAHVTLQ 235
Query: 275 APPVAGPSVFLFPPKPKDTLMISRTP-------EVTCVVVDVSHEDPEVQFNWYVDGMEV 327
P+ G + + TL +++ P VTC V + +Q W +G
Sbjct: 236 GDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQ--RLQLTWLENGNVS 293
Query: 328 HNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPR 387
E + T+ +S L V + + C+V + G PA + K P+
Sbjct: 294 RTETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPK 353
Query: 388 EPQVYTLP 395
E T P
Sbjct: 354 EQGSNTAP 361
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 52.8 bits (125), Expect = 7e-07
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPE-NNYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W N Q E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHN 477
+ + D +F + L + Q+G+V++C V H +L N
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQN 214
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 52.8 bits (125), Expect = 7e-07
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPE-NNYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W N Q E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHN 477
+ + D +F + L + Q+G+V++C V H +L N
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQN 214
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W N Q E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + D +F + L + Q+G+V++C V H +L + T
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|239748788 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 2 [Homo sapiens]
Length = 281
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W N Q E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + D +F + L + Q+G+V++C V H +L + T
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|239740863 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W N Q E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + D +F + L + Q+G+V++C V H +L + T
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|239513955 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 381 KTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPP 439
+T Q R T+ PSR E + L C V FYP+ I V W N Q E +TP
Sbjct: 120 RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPL 179
Query: 440 MLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + D +F + L + Q+G+V++C V H +L + T
Sbjct: 180 IRNGDWTFQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.5 bits (75), Expect = 0.45
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 50.4 bits (119), Expect = 4e-06
Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Query: 388 EPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPPMLDSDGS 446
EP V T+ PSR E + L C V FYP I V W N Q E +TP + + D +
Sbjct: 128 EPTV-TISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186
Query: 447 FFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
F + L + Q+G+V++C V H +L + T
Sbjct: 187 FQILVMLEMTP---QRGDVYTCHVEHPSLQSPIT 217
Score = 33.1 bits (74), Expect = 0.59
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 189 LGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSVVTVTSSNFGTQTYT 246
L C V D++P + V W N T+GV + P + + + ++ +T YT
Sbjct: 147 LVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQR--GDVYT 204
Query: 247 CNVDH 251
C+V+H
Sbjct: 205 CHVEH 209
>gi|4504403 major histocompatibility complex, class II, DO beta
precursor [Homo sapiens]
Length = 273
Score = 50.4 bits (119), Expect = 4e-06
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Query: 382 TKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPPM 440
T G+ +P+V T+ P R + L C V GFYP DI ++W NGQ E +T P+
Sbjct: 116 TVGRKVQPEV-TVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPI 174
Query: 441 LDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEAL 475
+ D +F L + + G+V++C V H +L
Sbjct: 175 RNGDWTFQTVVMLEMTP---ELGHVYTCLVDHSSL 206
>gi|94538339 signal-regulatory protein gamma isoform 3 precursor
[Homo sapiens]
Length = 276
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 7/131 (5%)
Query: 362 YKCKVSNKGLPAPIE-----KTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFY 416
Y C KG P +E T +P P V L P+ ++ VS TC GF
Sbjct: 117 YYCVKFRKGSPENVEFKSGPGTEMALGAKPSAPVV--LGPAARTTPEHTVSFTCESHGFS 174
Query: 417 PSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALH 476
P DI ++W NG ++++T ++ + S V W + C V H L
Sbjct: 175 PRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQ 234
Query: 477 NHYTQKSLSLS 487
+ + +LS
Sbjct: 235 GDPLRGTANLS 245
Score = 33.1 bits (74), Expect = 0.59
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 161 TSLAASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW-NSGALTSGVHTFPA 219
T +A K + L P +R+T E T + C + P +T+ W +G S T
Sbjct: 138 TEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVD 197
Query: 220 VLQSSGLYSLSSVVTVTSSNFGTQTYT-CNVDH 251
S YS+ S V + ++ C V H
Sbjct: 198 PTGQSVAYSIRSTARVVLDPWDVRSQVICEVAH 230
>gi|52630344 major histocompatibility complex, class II, DR beta 4
precursor [Homo sapiens]
Length = 266
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 388 EPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSF 447
+P+V T+ PS+ + ++ L C V GFYP I V W NGQ E + ++ +
Sbjct: 125 QPKV-TVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD-- 181
Query: 448 FLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + L + ++ + G V++C V H ++ + T
Sbjct: 182 WTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 214
>gi|239758090 PREDICTED: major histocompatibility complex, class II,
DR beta 4 [Homo sapiens]
Length = 278
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 388 EPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSF 447
+P+V T+ PS+ + ++ L C V GFYP I V W NGQ E + ++ +
Sbjct: 137 QPKV-TVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD-- 193
Query: 448 FLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + L + ++ + G V++C V H ++ + T
Sbjct: 194 WTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 226
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/122 (36%), Positives = 57/122 (46%), Gaps = 9/122 (7%)
Query: 31 AGGTGGSSGTSGDQGRASEGEQGLVGA-GRAG--GSPWSSGDQGRAATGEQGLVGSRRSR 87
A G G+ GT G QG A G++G+VG G+ G G P G G G+QG G+ R
Sbjct: 939 ADGPAGAPGTPGPQGIA--GQRGVVGLPGQRGERGFPGLPGPSGEP--GKQGPSGASGER 994
Query: 88 GQPLELRAPGQSTLSWLWGREWAKVRQVAPAR-CTPNAREPRHWTLP-GPSWIDKNRGAS 145
G P + PG + GRE A + +P R +P A+ R T P GP GA
Sbjct: 995 GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAP 1054
Query: 146 AP 147
P
Sbjct: 1055 GP 1056
Score = 38.9 bits (89), Expect = 0.011
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 33 GTGGSSGTSGDQG-RASEGEQGLVGAGRAGGSPWSSGDQGRAATGEQGLVGSRRSRGQPL 91
G G G +G+QG R +G +G G G P S G+Q G G G RG P
Sbjct: 1091 GPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQ-----GPSGASGPAGPRGPPG 1145
Query: 92 ELRAPGQSTLSWLWG 106
APG+ L+ L G
Sbjct: 1146 SAGAPGKDGLNGLPG 1160
Score = 37.0 bits (84), Expect = 0.041
Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 33 GTGGSSGTSGDQGRASE----GEQGLVGAGRAGGSPWSSGDQGRA----ATGEQGLVGSR 84
G G G +G GR E G QG G G P G +G + A G+ G G +
Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 85 RSRGQPLELRAPGQ 98
G P E APGQ
Sbjct: 287 GEPGSPGENGAPGQ 300
Score = 36.2 bits (82), Expect = 0.070
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 21/126 (16%)
Query: 33 GTGGSSGTSGDQG----RASEGEQGLVGAGRAGGSPWSSGDQG-------RAATGEQGLV 81
G G G +G++G R G GL G G P S G G + GE+G
Sbjct: 455 GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP 514
Query: 82 GSRRSRGQPLELRAPGQSTLSWLWGREWAKVRQVAPARCTPNAREPRHWTLPGPSWIDKN 141
G +G P E PG++ G AK +P P+ + PGP+ D
Sbjct: 515 GPAGPKGSPGEAGRPGEA------GLPGAKGLTGSPGSPGPDGKTGP----PGPAGQDGR 564
Query: 142 RGASAP 147
G P
Sbjct: 565 PGPPGP 570
Score = 35.8 bits (81), Expect = 0.091
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 9/74 (12%)
Query: 31 AGGTGGSSGTSGDQGRASEGEQGLVGAGRAGGSPWSSGDQGRA-------ATGEQGLVGS 83
A G G+ G G QG + G QG+ G A G P GD+G A + G+ G+ G
Sbjct: 708 AKGDAGAPGAPGSQG--APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL 765
Query: 84 RRSRGQPLELRAPG 97
G P APG
Sbjct: 766 TGPIGPPGPAGAPG 779
Score = 35.4 bits (80), Expect = 0.12
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 33 GTGGSSGTSGDQG-RASEGEQGLVGAGRAGGSPWSSGDQGRAATGEQGLVGSRRSRGQPL 91
G G+ G +G QG R SEG QG+ G G ++G G G G G++ + G P
Sbjct: 347 GAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN--PGADGQPGAKGANGAPG 404
Query: 92 ELRAPG 97
APG
Sbjct: 405 IAGAPG 410
Score = 35.0 bits (79), Expect = 0.15
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 33 GTGGSSGTSGDQGRASE----GEQGLVGAGRAGGSPWSSGDQGRAAT----GEQGLVGSR 84
G G G +G+ G+A E G G VG G + G G A GEQG GS
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640
Query: 85 RSRGQPLELRAPGQS 99
+G P PG++
Sbjct: 641 GFQGLPGPAGPPGEA 655
Score = 33.9 bits (76), Expect = 0.34
Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 33 GTGGSSGTSGDQG-RASEGEQGLVGAGRAGGSPWSSGDQGRAATGEQGLVGSRRSRGQP 90
G G G G G R + G G GA G+P + G QG A G QG+ G R + G P
Sbjct: 683 GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQG--APGLQGMPGERGAAGLP 739
Score = 32.3 bits (72), Expect = 1.0
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 33 GTGGSSGTSGDQGRASEGEQGLVGAGRAGGSPWSSGDQGRAATGEQGLVGSRRSRGQPLE 92
G G G G G+ +G +GL G G + GD+G +G G G +RG P +
Sbjct: 746 GDAGPKGADGSPGK--DGVRGLTGPIGPPGPAGAPGDKGE--SGPSGPAGPTGARGAPGD 801
Query: 93 LRAPG 97
PG
Sbjct: 802 RGEPG 806
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 33 GTGGSSGTSGDQGRASE-GEQGLVGAGRAGGSPWSSGDQGRA-ATGEQGLVGSRRSRGQP 90
G G+ G GD+G G G G A G P + G+ G A A G+ G G G P
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850
Score = 31.6 bits (70), Expect = 1.7
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 33 GTGGSSGTSGDQGRASE-GEQGLVGAGRAGGSPWSSGDQGRAATGEQGLVGSRRSRGQP 90
G G +G +G +G + GE G G G P + G G A GE G G++ G P
Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG--AKGEPGDAGAKGDAGPP 841
Score = 31.6 bits (70), Expect = 1.7
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 31 AGGTGGSSGTSGDQG-RASEGEQGLVGAGRAGGSPWSSGDQGRAA-TGEQGLVGSRRSRG 88
A G GS G G G + GE G G A G+P + G G A +G++G G G
Sbjct: 1017 APGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076
Query: 89 Q--PLELRAP 96
P+ R P
Sbjct: 1077 PVGPVGARGP 1086
Score = 30.8 bits (68), Expect = 2.9
Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 5/70 (7%)
Query: 33 GTGGSSGTSGDQGR-ASEGEQGLVGAGRAGGSPWSSGDQGRAA----TGEQGLVGSRRSR 87
G G +G G G+ ++GE G GA G P +G G G G G+R S
Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 88 GQPLELRAPG 97
G P PG
Sbjct: 869 GPPGATGFPG 878
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 44.7 bits (104), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 5/94 (5%)
Query: 388 EPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPEN-NYKTTPPMLDSDGS 446
+P+V + PS++ ++ L C V FYP I V W NGQ E +T + + D +
Sbjct: 123 QPRV-NVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
Query: 447 FFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
F + L + QQG+V++C V H +L + T
Sbjct: 182 FQILVMLEMTP---QQGDVYTCQVEHTSLDSPVT 212
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 175 LAPCSRSTSESTAALGCLVKDYFPEPVTVSW--NSGALTSGVHTFPAVLQSSGLYSLSSV 232
++P + + L C V D++P + V W N T+GV + + + + +
Sbjct: 128 VSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVM 187
Query: 233 VTVTSSNFGTQTYTCNVDHKPSNTKVDKTVERK 265
+ +T YTC V+H ++ V TVE K
Sbjct: 188 LEMTPQQ--GDVYTCQVEHTSLDSPV--TVEWK 216
>gi|155030211 major histocompatibility complex, class II, DR beta 1
precursor [Homo sapiens]
Length = 266
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 388 EPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSF 447
+P+V T+ PS+ + ++ L C V GFYP I V W NGQ E + ++ +
Sbjct: 125 QPKV-TVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNGD-- 181
Query: 448 FLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ + L + ++ + G V++C V H ++ + T
Sbjct: 182 WTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLT 214
>gi|169217452 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-4 beta chain, partial [Homo sapiens]
Length = 223
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 389 PQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFF 448
P+V T+ P++ + ++ L C V GFYP I V W NGQ E + ++ + +
Sbjct: 138 PEV-TVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGD--W 194
Query: 449 LYSKLTVDKSRWQQGNVFSCSVMHEAL 475
+ L + ++ + G V++C V H +L
Sbjct: 195 TFQTLVMLETVPRSGEVYTCQVEHPSL 221
>gi|17986005 major histocompatibility complex, class II, DR beta 3
precursor [Homo sapiens]
Length = 266
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 389 PQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFF 448
PQV T+ P++ + ++ L C V GFYP I V W NGQ E + ++ + +
Sbjct: 126 PQV-TVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD--W 182
Query: 449 LYSKLTVDKSRWQQGNVFSCSVMHEALHNHYT 480
+ L + ++ + G V++C V H ++ + T
Sbjct: 183 TFQTLVMLETVPRSGEVYTCQVEHPSVTSALT 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,452,380
Number of Sequences: 37866
Number of extensions: 1274612
Number of successful extensions: 7536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 5299
Number of HSP's gapped (non-prelim): 1954
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.