BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] (170 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 350 3e-97 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 80 8e-16 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 73 1e-13 gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 72 2e-13 gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 69 2e-12 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 69 3e-12 gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 65 2e-11 gi|27883882 P18SRP protein [Homo sapiens] 65 3e-11 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 61 5e-10 gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 60 7e-10 gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H... 60 7e-10 gi|168229156 NFKB activating protein [Homo sapiens] 60 1e-09 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 58 3e-09 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 58 3e-09 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 58 3e-09 gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 57 1e-08 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 57 1e-08 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 57 1e-08 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 57 1e-08 gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 57 1e-08 gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 57 1e-08 gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 55 2e-08 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 55 2e-08 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 55 2e-08 gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 55 3e-08 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 55 3e-08 gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 55 3e-08 gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 55 4e-08 gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 55 4e-08 gi|11067749 bromodomain containing protein 3 [Homo sapiens] 55 4e-08 >gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] Length = 170 Score = 350 bits (898), Expect = 3e-97 Identities = 170/170 (100%), Positives = 170/170 (100%) Query: 1 MLGHIFPGTGNLLPYEAAHFISGHFDHHILFHVYVSQIHPLLSKIITPCLLSTHSTHSDP 60 MLGHIFPGTGNLLPYEAAHFISGHFDHHILFHVYVSQIHPLLSKIITPCLLSTHSTHSDP Sbjct: 1 MLGHIFPGTGNLLPYEAAHFISGHFDHHILFHVYVSQIHPLLSKIITPCLLSTHSTHSDP 60 Query: 61 SATVLPGSSTHRLKGKIFHLISIAFCDAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKK 120 SATVLPGSSTHRLKGKIFHLISIAFCDAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKK Sbjct: 61 SATVLPGSSTHRLKGKIFHLISIAFCDAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKK 120 Query: 121 KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKIH 170 KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKIH Sbjct: 121 KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKIH 170 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 80.1 bits (196), Expect = 8e-16 Identities = 31/61 (50%), Positives = 58/61 (95%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 QR+E++EKE+ K+KK+KKK+++K++ ++++KKKK++K+++R+ K++R+RKRKK+RKKK++ Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144 Query: 161 K 161 K Sbjct: 145 K 145 Score = 73.6 bits (179), Expect = 8e-14 Identities = 30/72 (41%), Positives = 62/72 (86%), Gaps = 1/72 (1%) Query: 98 GLPQREEKKE-KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G +R++KKE KE+E++ K+++++K+KK++KKK++K++K++K++ KR+RKRK+++K++R+ Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169 Query: 157 KKKKKTGNEGAK 168 KK+++ E K Sbjct: 170 KKRERNRKERKK 181 Score = 71.6 bits (174), Expect = 3e-13 Identities = 25/61 (40%), Positives = 58/61 (95%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE+++++ +EK+++K+KK+KKK+++K++ ++++KKKK++++R+R+ K++R++KRKK++K Sbjct: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK 140 Query: 161 K 161 K Sbjct: 141 K 141 Score = 71.2 bits (173), Expect = 4e-13 Identities = 26/61 (42%), Positives = 56/61 (91%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE +KE+++E+ KK+KKK+KK+++ K++++K+K+++K++++R+ K +RKRKK++KK+++ Sbjct: 47 KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106 Query: 161 K 161 K Sbjct: 107 K 107 Score = 70.9 bits (172), Expect = 5e-13 Identities = 25/65 (38%), Positives = 60/65 (92%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++ +K+E+ KE+++K+K+++K++K++++K+++K+KK+KKKR+RK++ +R+RKKK+++K++ Sbjct: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123 Query: 161 KTGNE 165 + N+ Sbjct: 124 ERENK 128 Score = 70.9 bits (172), Expect = 5e-13 Identities = 27/68 (39%), Positives = 56/68 (82%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE K+ +E+KKKK++K+++++ K+++++K+KK++KKKR+++RKR+++R K+ +K+KK Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162 Query: 161 KTGNEGAK 168 + E K Sbjct: 163 RKKEEREK 170 Score = 70.5 bits (171), Expect = 7e-13 Identities = 26/61 (42%), Positives = 54/61 (88%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + + K+E+EKE+K+++ KK+KKK+KK+++ K++++K+K++ K++++R+ K ++KRKK+KK Sbjct: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKK 102 Query: 161 K 161 K Sbjct: 103 K 103 Score = 70.5 bits (171), Expect = 7e-13 Identities = 26/68 (38%), Positives = 59/68 (86%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE+++++E+ KK+KKK+KK+++ K++++K+K+++K++K+R+ K +RKRK++KK++++K+ Sbjct: 49 EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ 108 Query: 161 KTGNEGAK 168 + E K Sbjct: 109 RGRRERKK 116 Score = 70.5 bits (171), Expect = 7e-13 Identities = 28/70 (40%), Positives = 59/70 (84%), Gaps = 2/70 (2%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKK--KKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 +RE K+ +E+++KK++KKK++K++K++K+ K+++K+KK+KK +R++KR+R RK+++K++ Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183 Query: 159 KKKTGNEGAK 168 ++K E K Sbjct: 184 ERKERRERKK 193 Score = 69.7 bits (169), Expect = 1e-12 Identities = 25/65 (38%), Positives = 58/65 (89%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E+KK K++E+ K++++K+K+++K++K++++K+++K+KK K+KR+RK++ +++RKKKK+ Sbjct: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119 Query: 161 KTGNE 165 + E Sbjct: 120 RKERE 124 Score = 69.3 bits (168), Expect = 1e-12 Identities = 27/67 (40%), Positives = 58/67 (86%), Gaps = 2/67 (2%) Query: 101 QREEKKEKEKEKKKKK--KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 +++E+KE+E+E K+++ K+KK++KKK++K++K++K++ K++RKRK+++K +R+KKR++ Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175 Query: 159 KKKTGNE 165 +K+ E Sbjct: 176 RKERKKE 182 Score = 68.9 bits (167), Expect = 2e-12 Identities = 25/68 (36%), Positives = 58/68 (85%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+E+K +++ K+++K+KK+KK++++KK+++ +K++KK+R+RK +R+RK+++K++++KK Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202 Query: 161 KTGNEGAK 168 K + K Sbjct: 203 KERKKDRK 210 Score = 68.6 bits (166), Expect = 3e-12 Identities = 25/65 (38%), Positives = 55/65 (84%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + EK+++E+EK++K+++ KK+KKK+KK+++ K++++K+K + K++++R+ K++RK+KK+ Sbjct: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100 Query: 161 KTGNE 165 K E Sbjct: 101 KKKRE 105 Score = 68.6 bits (166), Expect = 3e-12 Identities = 24/68 (35%), Positives = 58/68 (85%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+ ++EKE+++++ KK+KKK+KK+++ K++++K+K+++K++++R+ K +RK+K++KKK+ Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKR 104 Query: 161 KTGNEGAK 168 + G + Sbjct: 105 ERKQRGRR 112 Score = 68.6 bits (166), Expect = 3e-12 Identities = 30/71 (42%), Positives = 58/71 (81%), Gaps = 6/71 (8%) Query: 101 QREEKKEKEK---EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK---RKKK 154 ++E K+EKE+ E+K+KK+KK++++KK+++ +K++KK++++K +R+RK++RK RKKK Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203 Query: 155 RKKKKKKTGNE 165 +KK +KT + Sbjct: 204 ERKKDRKTDRQ 214 Score = 68.2 bits (165), Expect = 3e-12 Identities = 26/69 (37%), Positives = 57/69 (82%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P + + E++KE+++++K+K++++K++K+++ KK+KKK+KKR+R ++R+RKRK++ K++K Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87 Query: 160 KKTGNEGAK 168 ++ E K Sbjct: 88 ERREKERRK 96 Score = 68.2 bits (165), Expect = 3e-12 Identities = 23/68 (33%), Positives = 61/68 (89%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 G +++++K++E+ K++++K+K+++K++K++++K+++K+KK+K+KR+RK++ +R++K+KK Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118 Query: 158 KKKKTGNE 165 ++K+ E Sbjct: 119 ERKERERE 126 Score = 67.8 bits (164), Expect = 4e-12 Identities = 28/73 (38%), Positives = 56/73 (76%), Gaps = 5/73 (6%) Query: 101 QREEKKEKEKEKKKKKKKKKK-----KKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155 QR E+K K++ KKK++K++K+ K+++K+KK+KK++++KK++R RK ++K + +K+R Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188 Query: 156 KKKKKKTGNEGAK 168 +++KK+ E K Sbjct: 189 RERKKERKKERRK 201 Score = 67.8 bits (164), Expect = 4e-12 Identities = 27/66 (40%), Positives = 58/66 (87%), Gaps = 5/66 (7%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKK-----KKKKKKKKRKRKRKRKRKRKKKR 155 +++ +KE+++EK++ K+++K+KK+KK++++KK K++KK+++RK +R+RK++RKK+R Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199 Query: 156 KKKKKK 161 +KKK++ Sbjct: 200 RKKKER 205 Score = 67.0 bits (162), Expect = 7e-12 Identities = 23/68 (33%), Positives = 59/68 (86%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +++E++E+EK K++++K++K+++ KK+KKK+KK+++ K++ +++++R+++RK++R+K+++ Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95 Query: 161 KTGNEGAK 168 K E K Sbjct: 96 KRKKEKKK 103 Score = 66.6 bits (161), Expect = 1e-11 Identities = 23/65 (35%), Positives = 57/65 (87%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE KE+E+++K+++K++K++++K+++K+KK+KKK+++K++ +R+RK+K+++K ++++ Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127 Query: 161 KTGNE 165 K E Sbjct: 128 KQRRE 132 Score = 60.8 bits (146), Expect = 5e-10 Identities = 20/61 (32%), Positives = 53/61 (86%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 G +R+ KK K++E++KK+++ +K++KK++++K+++++KK++K++R++K++RK+ +K + Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213 Query: 158 K 158 + Sbjct: 214 Q 214 Score = 44.3 bits (103), Expect = 5e-05 Identities = 18/63 (28%), Positives = 42/63 (66%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R K+ K++ ++K+++++KK++KK+++KKK++KK +K R+ + R ++ + Sbjct: 173 ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVT 232 Query: 161 KTG 163 TG Sbjct: 233 VTG 235 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 72.8 bits (177), Expect = 1e-13 Identities = 32/65 (49%), Positives = 53/65 (81%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + EE +E E+E++K+ K+K+K+K+K+K+K+KKKK K+ +KRK K + ++KRK+KRKKKK+ Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71 Query: 161 KTGNE 165 + E Sbjct: 72 EEERE 76 Score = 71.2 bits (173), Expect = 4e-13 Identities = 30/63 (47%), Positives = 54/63 (85%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E ++E+EKE K+K+K+K+K+K+K+KKKK K+ +K+K+K + ++KRKRKRKKK+++++++ Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77 Query: 163 GNE 165 E Sbjct: 78 EEE 80 Score = 70.9 bits (172), Expect = 5e-13 Identities = 29/65 (44%), Positives = 56/65 (86%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + EE++EKE ++K+K+K+K+K+K+KKKK K+ +K+K+K++ ++KRKRKRK+KK+ +++++ Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77 Query: 161 KTGNE 165 + E Sbjct: 78 EEEEE 82 Score = 69.3 bits (168), Expect = 1e-12 Identities = 29/65 (44%), Positives = 53/65 (81%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + E+ E+E+EK+ K+K+K+K+K+K+K+KKKK K+ +K+K K + ++KRKRK+K+KK+++ Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE 73 Query: 161 KTGNE 165 + E Sbjct: 74 EREEE 78 Score = 68.2 bits (165), Expect = 3e-12 Identities = 32/76 (42%), Positives = 55/76 (72%), Gaps = 15/76 (19%) Query: 101 QREEKKEKEKEKKKKKKKKKKKK---------------KKKKKKKKKKKKKKKKKRKRKR 145 + E++KEKE+E+KK+K+K+KKKK K++++K++ +++KKKKKR+RK Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 Query: 146 KRKRKRKKKRKKKKKK 161 + + K+KK+R+K KKK Sbjct: 108 EEEEKKKKRRRKTKKK 123 Score = 67.4 bits (163), Expect = 6e-12 Identities = 26/65 (40%), Positives = 57/65 (87%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + EE+KE ++++K+K+K+K+K+KKKK K+ +K+K+K+++++KRKRKRK+K++++ +++++ Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79 Query: 161 KTGNE 165 + E Sbjct: 80 EEEEE 84 Score = 67.4 bits (163), Expect = 6e-12 Identities = 26/68 (38%), Positives = 56/68 (82%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E++KEK KEK+KKKK K+ +K+K+K++++KK+K+K+KK+K + +R+ + +++ ++K++ Sbjct: 29 RKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE 88 Query: 161 KTGNEGAK 168 + EG + Sbjct: 89 EEKEEGRR 96 Score = 66.2 bits (160), Expect = 1e-11 Identities = 37/94 (39%), Positives = 59/94 (62%), Gaps = 26/94 (27%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKK-KKKKKKKKKKKKKKKRKRKRKRK----------- 148 + EEK+ K KEK+K+K+K+K+KKKK K+ +K+K+K++++KKRKRKRK+K Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80 Query: 149 --------------RKRKKKRKKKKKKTGNEGAK 168 R+RKKK+K+++K+ E K Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 Score = 65.1 bits (157), Expect = 3e-11 Identities = 31/88 (35%), Positives = 58/88 (65%), Gaps = 26/88 (29%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK---------------------- 138 ++E++KEKEK+KK K+ +K+K+K++++KK+K+K+KKKK Sbjct: 33 RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 Query: 139 ----KKRKRKRKRKRKRKKKRKKKKKKT 162 +K+K+KR+RK + ++K+KK+++KT Sbjct: 93 EGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 Score = 64.3 bits (155), Expect = 5e-11 Identities = 28/62 (45%), Positives = 48/62 (77%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 E+ E+ +E +++++K+ K+K+K+K+K+K+K+KKKK K KRK K + +KKRK+K+KK Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70 Query: 164 NE 165 E Sbjct: 71 EE 72 Score = 62.0 bits (149), Expect = 2e-10 Identities = 29/69 (42%), Positives = 52/69 (75%), Gaps = 4/69 (5%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK----RKKKRK 156 +++E +E E+ ++ +++++K+ K+K+K+K+K+K+K+KKKK K KRK K +K+KRK Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 Query: 157 KKKKKTGNE 165 +KKKK E Sbjct: 66 RKKKKEEEE 74 Score = 53.5 bits (127), Expect = 8e-08 Identities = 23/60 (38%), Positives = 45/60 (75%) Query: 109 EKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 +K+KKKKK+ ++ ++ ++ +++++K+ K+K+KRK KRK K K+KK ++ +K+K E K Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 Score = 34.7 bits (78), Expect = 0.041 Identities = 13/30 (43%), Positives = 25/30 (83%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKK 127 G ++++KK + KE++++KKKK+++K KKK Sbjct: 94 GRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 >gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo sapiens] Length = 929 Score = 72.0 bits (175), Expect = 2e-13 Identities = 34/63 (53%), Positives = 50/63 (79%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 LP EK +EKEK K+K+KKK KK+KKKKK+K+K+KK+K++ K KR+R+++ K+K K K Sbjct: 682 LPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHK 741 Query: 159 KKK 161 +K Sbjct: 742 HEK 744 Score = 71.6 bits (174), Expect = 3e-13 Identities = 39/71 (54%), Positives = 58/71 (81%), Gaps = 4/71 (5%) Query: 90 PSLHLPLHGLPQRE-EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148 PSL LP+ LP++ E+KEK KEK+KKK KK+KKKKK+K+K+KK+K+++K+KR+R+++ K Sbjct: 679 PSL-LPV--LPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREK 735 Query: 149 RKRKKKRKKKK 159 K K K +K K Sbjct: 736 EKEKHKHEKIK 746 Score = 63.2 bits (152), Expect = 1e-10 Identities = 27/61 (44%), Positives = 52/61 (85%) Query: 109 EKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 EK ++K+K K+K+KKK KK+KKKKK+K+K+K++++R+++++ ++KR+K+K+K +E K Sbjct: 687 EKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIK 746 Query: 169 I 169 + Sbjct: 747 V 747 Score = 55.5 bits (132), Expect = 2e-08 Identities = 31/71 (43%), Positives = 44/71 (61%), Gaps = 3/71 (4%) Query: 95 PLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 PLH + E+K K + KKK KK+ K K KKK+K++ ++++K K K K K K K K Sbjct: 504 PLHKV---YEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVK 560 Query: 155 RKKKKKKTGNE 165 K+K K+TG E Sbjct: 561 EKEKDKETGRE 571 Score = 47.4 bits (111), Expect = 6e-06 Identities = 24/59 (40%), Positives = 36/59 (61%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 LP E K+K K++ K K KKK+K++ ++++K K K K K+K K K K K K + K Sbjct: 515 LPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETK 573 Score = 47.4 bits (111), Expect = 6e-06 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 51/134 (38%) Query: 85 FCDAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKK------------ 132 F D P + L GL ++E++K K+K+K ++K KK K K++K+K K K Sbjct: 595 FEDVDPKVKLK-DGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPP 653 Query: 133 --------------------------------------KKKKKKKKRKRKRKRKRKRKKK 154 +K+K K+K K+K K+++K+KK+ Sbjct: 654 LVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKE 713 Query: 155 RKKKKKKTGNEGAK 168 ++K+KK+ E K Sbjct: 714 KEKEKKEKEREKEK 727 Score = 42.7 bits (99), Expect = 1e-04 Identities = 23/64 (35%), Positives = 38/64 (59%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 +KK K++ K K KKK+K++ ++++K K K K K+K K K K K K ++ + K+ Sbjct: 522 KKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLK 581 Query: 164 NEGA 167 E A Sbjct: 582 EEEA 585 Score = 42.0 bits (97), Expect = 3e-04 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 41/106 (38%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKK------------------------------ 130 QR+ ++EK+K K K K+K K K+K+K K+ Sbjct: 539 QRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDV 598 Query: 131 -----------KKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 +K+K+K K K+K + K K+ + K+ K+K K G E Sbjct: 599 DPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGRE 644 Score = 41.2 bits (95), Expect = 4e-04 Identities = 19/61 (31%), Positives = 41/61 (67%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +++ KKE + + KKK+K++ ++++K K K K K+K K K++++ ++ R+ K K+ K Sbjct: 522 KKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLK 581 Query: 161 K 161 + Sbjct: 582 E 582 Score = 40.8 bits (94), Expect = 6e-04 Identities = 21/56 (37%), Positives = 36/56 (64%) Query: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 K+ ++ + K K K +K+K+K K KKK ++K KK K KR++++ + K R+ K K Sbjct: 593 KEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMK 648 Score = 40.0 bits (92), Expect = 0.001 Identities = 22/62 (35%), Positives = 35/62 (56%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P + + KE E K K K +K+K+K K KKK ++K K+ + ++ K K K K ++ K Sbjct: 587 PYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDK 646 Query: 160 KK 161 K Sbjct: 647 MK 648 Score = 39.7 bits (91), Expect = 0.001 Identities = 19/59 (32%), Positives = 38/59 (64%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E K K K+K+K++ ++++K K K K K+K K K+K+K K + + K+ K+++ Sbjct: 526 KKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEE 584 Score = 39.3 bits (90), Expect = 0.002 Identities = 18/59 (30%), Positives = 40/59 (67%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 ++E K + +K++K++ ++++K K K K K+K K K+K+K ++ R+ K K+ K+++ Sbjct: 526 KKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEE 584 Score = 38.9 bits (89), Expect = 0.002 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 39/110 (35%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKK---KKKKKKKKKKKKKK--------------- 140 L + +KKEK+++++++K K K K K+K K+K+K K+ ++ K Sbjct: 529 LKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPY 588 Query: 141 ---------------------RKRKRKRKRKRKKKRKKKKKKTGNEGAKI 169 RK K K K K+K + K KK K E K+ Sbjct: 589 KFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKV 638 Score = 35.4 bits (80), Expect = 0.024 Identities = 18/53 (33%), Positives = 29/53 (54%) Query: 117 KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKI 169 K ++K K + KKK KK+ K K K+K K++ +++ K K K E K+ Sbjct: 507 KVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKV 559 Score = 35.0 bits (79), Expect = 0.031 Identities = 19/58 (32%), Positives = 30/58 (51%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 E K ++K K + KKK KK+ K K K+K K++ + ++K K K K + K Sbjct: 503 EPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVK 560 >gi|117553580 adaptor-related protein complex 3, delta 1 subunit isoform 2 [Homo sapiens] Length = 1153 Score = 68.9 bits (167), Expect = 2e-12 Identities = 33/73 (45%), Positives = 49/73 (67%) Query: 95 PLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 P +P E+K +K K+K+KK K+K++ K+KKK+K+KKK K KKK+ RK K +R + KK Sbjct: 830 PEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKK 889 Query: 155 RKKKKKKTGNEGA 167 + KK+ E A Sbjct: 890 KSKKQPPGSEEAA 902 Score = 60.8 bits (146), Expect = 5e-10 Identities = 29/68 (42%), Positives = 44/68 (64%) Query: 94 LPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 LP+ E K EK+ +KK KK KKK+KK K+K++ K+KKK K K+K + +KK Sbjct: 816 LPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKK 875 Query: 154 KRKKKKKK 161 K +K+K++ Sbjct: 876 KHRKEKEE 883 Score = 59.7 bits (143), Expect = 1e-09 Identities = 27/74 (36%), Positives = 49/74 (66%) Query: 90 PSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149 P +P+ ++ KK+++K K+K++ K+KKK+K+KKK K KKKK +K+++ + K K+ Sbjct: 830 PEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKK 889 Query: 150 KRKKKRKKKKKKTG 163 K KK+ ++ G Sbjct: 890 KSKKQPPGSEEAAG 903 Score = 59.7 bits (143), Expect = 1e-09 Identities = 29/67 (43%), Positives = 46/67 (68%), Gaps = 2/67 (2%) Query: 101 QREEKKEKEKEKKKKKKK--KKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 +++ KK K+KEKK K+K+ K+KKK+K+KKK K KKKK +K K +R + +K+ KK+ Sbjct: 838 EKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPG 897 Query: 159 KKKTGNE 165 ++ E Sbjct: 898 SEEAAGE 904 Score = 59.3 bits (142), Expect = 2e-09 Identities = 27/77 (35%), Positives = 50/77 (64%) Query: 92 LHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR 151 L + H + + EK+ +KK KK KKK+KK K+K++ K+KKK+K K+K + +K+ Sbjct: 816 LPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKK 875 Query: 152 KKKRKKKKKKTGNEGAK 168 K +++K+++ G + +K Sbjct: 876 KHRKEKEERTKGKKKSK 892 Score = 52.8 bits (125), Expect = 1e-07 Identities = 29/70 (41%), Positives = 38/70 (54%) Query: 92 LHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR 151 L PL + +K + E K +K +KK KK KKK+KK K+K + K K+K K Sbjct: 806 LDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKE 865 Query: 152 KKKRKKKKKK 161 KKK K KKK Sbjct: 866 KKKSPKPKKK 875 Score = 45.1 bits (105), Expect = 3e-05 Identities = 22/64 (34%), Positives = 38/64 (59%) Query: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEG 166 EK +K + + K +K +KK KK KKK K+ ++++R ++KK++K+KKK+ Sbjct: 814 EKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPK 873 Query: 167 AKIH 170 K H Sbjct: 874 KKKH 877 Score = 41.2 bits (95), Expect = 4e-04 Identities = 17/47 (36%), Positives = 35/47 (74%) Query: 91 SLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKK 137 S+ L + GLP ++ + E+E++ ++K +K K++KK+K+K+KK K++ Sbjct: 710 SVPLKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRR 756 Score = 38.5 bits (88), Expect = 0.003 Identities = 20/74 (27%), Positives = 38/74 (51%) Query: 95 PLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 P L +K + EK +K + + K +K +KK KK K+K K+ +++++ Sbjct: 798 PYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERD 857 Query: 155 RKKKKKKTGNEGAK 168 ++KKK+K + K Sbjct: 858 KEKKKEKEKKKSPK 871 Score = 32.0 bits (71), Expect = 0.26 Identities = 12/31 (38%), Positives = 24/31 (77%) Query: 125 KKKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155 K +++++ ++K +K KR++KRK K K+ K+R Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRR 756 Score = 31.6 bits (70), Expect = 0.34 Identities = 13/27 (48%), Positives = 22/27 (81%) Query: 135 KKKKKKRKRKRKRKRKRKKKRKKKKKK 161 K ++++R R++ K KR+KKRK+K+KK Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKK 752 Score = 30.4 bits (67), Expect = 0.77 Identities = 11/31 (35%), Positives = 24/31 (77%) Query: 127 KKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 K +++++ ++K +K KR++KRK K KK +++ Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRR 756 Score = 30.4 bits (67), Expect = 0.77 Identities = 11/31 (35%), Positives = 24/31 (77%) Query: 129 KKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 K +++++ ++K K KR++KRK K+K+ K++ Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRR 756 Score = 30.4 bits (67), Expect = 0.77 Identities = 11/31 (35%), Positives = 24/31 (77%) Query: 131 KKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 K +++++ +++ K KR++KRK+K KK K++ Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRR 756 Score = 28.9 bits (63), Expect = 2.2 Identities = 9/40 (22%), Positives = 29/40 (72%) Query: 126 KKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 K +++++ ++K +K ++RK+++++++K KR+ T ++ Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESD 765 Score = 27.7 bits (60), Expect = 5.0 Identities = 11/32 (34%), Positives = 20/32 (62%) Query: 139 KKRKRKRKRKRKRKKKRKKKKKKTGNEGAKIH 170 K + +R R++ K KR+KK+K+ +G + H Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRRH 757 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 68.6 bits (166), Expect = 3e-12 Identities = 29/68 (42%), Positives = 57/68 (83%), Gaps = 1/68 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E KKE+E E+KK++++++K+K++++K++K+++ KK+KK +RK K +R+RKK+R++K+ Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK-KEERERKKRRREKEN 106 Query: 161 KTGNEGAK 168 K G E K Sbjct: 107 KEGEEKEK 114 Score = 66.6 bits (161), Expect = 1e-11 Identities = 26/71 (36%), Positives = 61/71 (85%), Gaps = 3/71 (4%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKK---KKKKKKKKKRKRKRKRKRKRKKKRKK 157 +REE+KE+E++K++++K++++K++KK+++K+ K++++K+K+RK ++KR+R RK+++K+ Sbjct: 140 KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199 Query: 158 KKKKTGNEGAK 168 +++K E K Sbjct: 200 RERKERRERKK 210 Score = 66.2 bits (160), Expect = 1e-11 Identities = 25/71 (35%), Positives = 62/71 (87%), Gaps = 3/71 (4%) Query: 101 QREEKKEKEKEKKKKKKKKKKK---KKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 +++E++EKE+E+K++KK+++K+ K++++K+K++K++KK+++ +++RK++R+RK++R++ Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208 Query: 158 KKKKTGNEGAK 168 KK++ E K Sbjct: 209 KKERKKKEERK 219 Score = 65.9 bits (159), Expect = 2e-11 Identities = 27/72 (37%), Positives = 56/72 (77%), Gaps = 6/72 (8%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKR------KRKRKKK 154 +++E++E+EK K++++K++K+++ KK+KK ++KK+++++K++R+ K K KRKKK Sbjct: 59 RKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKK 118 Query: 155 RKKKKKKTGNEG 166 KK++ +T EG Sbjct: 119 EKKERGRTSKEG 130 Score = 64.7 bits (156), Expect = 4e-11 Identities = 29/73 (39%), Positives = 58/73 (79%), Gaps = 12/73 (16%) Query: 101 QREEKKE-KEKEKKKKKKKKK-----------KKKKKKKKKKKKKKKKKKKKRKRKRKRK 148 +RE KKE +EKE+++K++KK+ +K+K++K++KK+++ +K++K++R+RK + Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205 Query: 149 RKRKKKRKKKKKK 161 R+RKK+RKKK+++ Sbjct: 206 RERKKERKKKEER 218 Score = 64.7 bits (156), Expect = 4e-11 Identities = 26/61 (42%), Positives = 56/61 (91%), Gaps = 1/61 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE K+ EKE+++K+K++K++KK+++ +K++KK++++K+R R+RK++RK+K++RKK+++ Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER-RERKKERKKKEERKKERQ 223 Query: 161 K 161 K Sbjct: 224 K 224 Score = 63.9 bits (154), Expect = 6e-11 Identities = 22/68 (32%), Positives = 56/68 (82%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + EE+KEKE++++KK+++ +K++KK++++K+++++KK++K+K +RK++R++ ++ ++K Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233 Query: 161 KTGNEGAK 168 + G K Sbjct: 234 ERGKRERK 241 Score = 63.5 bits (153), Expect = 8e-11 Identities = 25/66 (37%), Positives = 57/66 (86%), Gaps = 1/66 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKK-KKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 +R++ EKE+E+K+K++K++KK+++ +K++KK++++K++++RK++RK+K +RKK+R+K + Sbjct: 167 ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226 Query: 160 KKTGNE 165 + E Sbjct: 227 QTNWRE 232 Score = 62.4 bits (150), Expect = 2e-10 Identities = 25/65 (38%), Positives = 51/65 (78%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + E+K++ +EK+ K+ ++K+K+KKK+KK++ + K+ K+R+RK +RKR+ +K+R++KK+ Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152 Query: 161 KTGNE 165 + E Sbjct: 153 EREKE 157 Score = 62.4 bits (150), Expect = 2e-10 Identities = 23/72 (31%), Positives = 60/72 (83%), Gaps = 7/72 (9%) Query: 101 QREEKKEKEKEKKKKKKKKKK-------KKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 ++E K+ +EKEK+KKK+KK++ K++++K+++K++++K+++++K +R+++R+RK+ Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162 Query: 154 KRKKKKKKTGNE 165 ++K+++K+ G + Sbjct: 163 RKKRERKQVGEK 174 Score = 62.4 bits (150), Expect = 2e-10 Identities = 23/64 (35%), Positives = 57/64 (89%), Gaps = 3/64 (4%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK---RKRKRKKKRKK 157 +R+E+K++E+ +K++KK++++K+++++KK++KKK+++KK+R++ R+ R+++R K+ +K Sbjct: 182 ERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241 Query: 158 KKKK 161 ++KK Sbjct: 242 ERKK 245 Score = 61.6 bits (148), Expect = 3e-10 Identities = 26/73 (35%), Positives = 58/73 (79%), Gaps = 8/73 (10%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKR--------KRKRKRKRKRK 152 ++E+K E++KE++++KK++++K+ K+ ++K+K+KKK+KK+R +R+RK +RKR+ Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142 Query: 153 KKRKKKKKKTGNE 165 +++++++KK E Sbjct: 143 ERKERERKKEERE 155 Score = 60.8 bits (146), Expect = 5e-10 Identities = 20/60 (33%), Positives = 54/60 (90%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE K+E+++E++K++++KK++++K++++K++KK+++K+ +++ +RK K +K+RKK+++ Sbjct: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191 Score = 60.1 bits (144), Expect = 9e-10 Identities = 26/66 (39%), Positives = 52/66 (78%), Gaps = 1/66 (1%) Query: 101 QREEKKEK-EKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 +RE KK + EKE K+ ++K+K+KKK+KK++ + K+ K+++RK +RKR+ +++++RKK++ Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153 Query: 160 KKTGNE 165 ++ E Sbjct: 154 REKERE 159 Score = 59.3 bits (142), Expect = 2e-09 Identities = 20/60 (33%), Positives = 55/60 (91%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R K+ KE+E+K+++K++++K++++KK++++K++++K+++KR+RK+ +++++RK+K++K Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184 Score = 59.3 bits (142), Expect = 2e-09 Identities = 22/65 (33%), Positives = 57/65 (87%), Gaps = 3/65 (4%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKR---KRKRKRKKKRKKKK 159 +E KE+E+++++K++++K++++KK++++K++++K++KKR+RK+ K + +++K+RK++K Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187 Query: 160 KKTGN 164 K+ N Sbjct: 188 KRERN 192 Score = 59.3 bits (142), Expect = 2e-09 Identities = 20/61 (32%), Positives = 51/61 (83%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + E K+E+ KE+++KK++++K++++K++KK+++K+ +K+ +RK K +++RKK+ + +K+ Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195 Query: 161 K 161 + Sbjct: 196 R 196 Score = 58.5 bits (140), Expect = 3e-09 Identities = 26/71 (36%), Positives = 53/71 (74%), Gaps = 3/71 (4%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKK---KRKRKRKRKRKRKKKRKK 157 +RE +KE+++E+ KK+KK ++KK+++++KK++++K+ K+ K KRK+K K++R + K+ Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129 Query: 158 KKKKTGNEGAK 168 K++ E K Sbjct: 130 GKERERKEERK 140 Score = 57.8 bits (138), Expect = 4e-09 Identities = 20/61 (32%), Positives = 51/61 (83%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE + E KE KK+++ ++KK++++++K+K++++K++K+ + K+++K +RKK+ +++KK Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99 Query: 161 K 161 + Sbjct: 100 R 100 Score = 56.2 bits (134), Expect = 1e-08 Identities = 19/65 (29%), Positives = 55/65 (84%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +++EKKE+ + K+ K++++K+++K++++K++++KK++++++R+RK ++KR++K+ +K+ Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175 Query: 161 KTGNE 165 + E Sbjct: 176 EERKE 180 >gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] Length = 248 Score = 65.5 bits (158), Expect = 2e-11 Identities = 30/43 (69%), Positives = 40/43 (93%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK 144 +E++KEKEKEK+K+K+K+K+K+K+KKKKKKKKKKKKKKK K Sbjct: 74 KEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116 Score = 65.1 bits (157), Expect = 3e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 20/92 (21%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKK--------------------KKKKKKKKKKKK 137 G ++ KK+K+K+ KKKKK KKK K+K+K+K+K+K+ Sbjct: 26 GRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKE 85 Query: 138 KKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKI 169 K+K K K K K K+KKK+KKKKKK AK+ Sbjct: 86 KEKEKEKEKEKEKKKKKKKKKKKKKKKLNAKV 117 Score = 62.4 bits (150), Expect = 2e-10 Identities = 37/89 (41%), Positives = 53/89 (59%), Gaps = 29/89 (32%) Query: 101 QREEKKEKEKEKKKKK---KKKKK--------------------------KKKKKKKKKK 131 +R KK+ K+KKKKK KKKKK K+K+K+K+K+ Sbjct: 24 KRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKE 83 Query: 132 KKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 K+K+K+K+K K K K+K+K+KKK+KKKKK Sbjct: 84 KEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112 Score = 58.2 bits (139), Expect = 3e-09 Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 26/89 (29%) Query: 103 EEKKEKEKEKKKKKK--------------------------KKKKKKKKKKKKKKKKKKK 136 ++KK+K+ KKKKK K+K+K+K+K+K+K+K+K+K Sbjct: 33 KKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEK 92 Query: 137 KKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 +K+K K+K+K+K+K+KKK+K K G E Sbjct: 93 EKEKEKKKKKKKKKKKKKKKLNAKVCGLE 121 Score = 50.1 bits (118), Expect = 9e-07 Identities = 28/59 (47%), Positives = 33/59 (55%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 EK EK+ K+ +KKK KKKKKKK KKKKK K+K K KK+ KK T Sbjct: 11 EKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTT 69 Score = 43.1 bits (100), Expect = 1e-04 Identities = 24/61 (39%), Positives = 34/61 (55%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E K EK +K+ K+ +KKK KKKKKKK +K+K+ +KK K KK+ Sbjct: 2 QELDKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKR 61 Query: 162 T 162 T Sbjct: 62 T 62 >gi|27883882 P18SRP protein [Homo sapiens] Length = 155 Score = 65.1 bits (157), Expect = 3e-11 Identities = 34/70 (48%), Positives = 47/70 (67%), Gaps = 11/70 (15%) Query: 101 QREEKKEKEKEKKKKKKKKKK-----------KKKKKKKKKKKKKKKKKKKRKRKRKRKR 149 + E+KKEK KEK K KKK+K+ K+KK+K +KK+KKK+KK + +K K + Sbjct: 73 EEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHK 132 Query: 150 KRKKKRKKKK 159 K KKKRKK+K Sbjct: 133 KEKKKRKKEK 142 Score = 60.5 bits (145), Expect = 7e-10 Identities = 34/83 (40%), Positives = 52/83 (62%), Gaps = 13/83 (15%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKK-------------KKKKKKKKKKKRK 142 L+ L +EK+ E+E+KKK+K K+K K KKK+K K+KK+K +KK++K Sbjct: 59 LNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKK 118 Query: 143 RKRKRKRKRKKKRKKKKKKTGNE 165 +++K K K+ K KK+KKK E Sbjct: 119 KEKKSKSKKGKHHKKEKKKRKKE 141 Score = 50.1 bits (118), Expect = 9e-07 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 11/79 (13%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKR-----------KRKRKRKR 151 +E+ E+ + + ++K+ ++++KKK+K K+K K KKKRKR +++K+K Sbjct: 53 DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY 112 Query: 152 KKKRKKKKKKTGNEGAKIH 170 +KK KKK+KK+ ++ K H Sbjct: 113 QKKEKKKEKKSKSKKGKHH 131 Score = 49.3 bits (116), Expect = 2e-06 Identities = 22/55 (40%), Positives = 36/55 (65%) Query: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 E++ K+KK+K +KK+KKK+KK K KK K KK++K+++K K + +K Sbjct: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155 Score = 48.9 bits (115), Expect = 2e-06 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 11/79 (13%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKK-----------KRKRKRKRKR 149 + EE + + ++K+ ++++KKK+K K+K K KKK+K+ +++K+K ++ Sbjct: 55 ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQK 114 Query: 150 KRKKKRKKKKKKTGNEGAK 168 K KKK KK K K G K Sbjct: 115 KEKKKEKKSKSKKGKHHKK 133 Score = 48.9 bits (115), Expect = 2e-06 Identities = 23/50 (46%), Positives = 34/50 (68%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152 ++KK+K ++K+KKK+KK K KK K KK+KKK+KK+K + RK Sbjct: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155 Score = 48.5 bits (114), Expect = 3e-06 Identities = 22/54 (40%), Positives = 36/54 (66%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 E+ +++K+K +KK+KKK+KK K KK K KK+KKK+K+++ + RK Sbjct: 102 EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155 Score = 48.1 bits (113), Expect = 4e-06 Identities = 25/56 (44%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 EE K+K K+K +KK+KKK+KK K KK K KK+KKKRK+++ + +K Sbjct: 101 EEDTSKQK-KQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155 Score = 47.8 bits (112), Expect = 5e-06 Identities = 23/46 (50%), Positives = 30/46 (65%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146 Q+ +KKEK+KEKK K KK K KK+KKK+KK+K + RK Sbjct: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155 Score = 47.0 bits (110), Expect = 8e-06 Identities = 22/50 (44%), Positives = 34/50 (68%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 +++++K ++KEKKK+KK K KK K KK+KKK+KK+K + RK Sbjct: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 60.8 bits (146), Expect = 5e-10 Identities = 20/63 (31%), Positives = 54/63 (85%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+ ++E+E+++++++K++ +++++ +++++KK++KK+RK++RK K+K +K+R+ KK+ Sbjct: 135 ERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194 Query: 161 KTG 163 K G Sbjct: 195 KWG 197 Score = 57.0 bits (136), Expect = 8e-09 Identities = 20/67 (29%), Positives = 56/67 (83%), Gaps = 1/67 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK-KKRKKKK 159 +RE ++++E+E+++++++K++ +++++ +++++KK++K++RK++RK K+K +KR++ K Sbjct: 133 ERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192 Query: 160 KKTGNEG 166 K+ EG Sbjct: 193 KRKWGEG 199 Score = 56.2 bits (134), Expect = 1e-08 Identities = 17/61 (27%), Positives = 54/61 (88%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 Q E ++++E+E+++++++++++++++K++ +++++ ++ +RK++RK++RKK+RK+KKK Sbjct: 125 QTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKK 184 Query: 161 K 161 + Sbjct: 185 E 185 Score = 55.5 bits (132), Expect = 2e-08 Identities = 16/61 (26%), Positives = 54/61 (88%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE +E+E+++++++++++++++K++ +++++ ++++RK++RK++RK+++K KKK++ Sbjct: 127 ERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEE 186 Query: 161 K 161 K Sbjct: 187 K 187 Score = 53.5 bits (127), Expect = 8e-08 Identities = 13/61 (21%), Positives = 56/61 (91%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+ ++E+++++++++++++++K++ +++++ +++++K++RK++RK++RK+K+K++K+ Sbjct: 129 ERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKR 188 Query: 161 K 161 + Sbjct: 189 R 189 Score = 52.0 bits (123), Expect = 2e-07 Identities = 14/65 (21%), Positives = 55/65 (84%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+++ E+E+++++++++++++++++++++K++ +++++ + +RK++RKK+RKK++K Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180 Query: 161 KTGNE 165 + E Sbjct: 181 EKKKE 185 Score = 47.4 bits (111), Expect = 6e-06 Identities = 22/83 (26%), Positives = 55/83 (66%), Gaps = 16/83 (19%) Query: 102 REEKKEKEKEKKKKKK---KKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR--------- 149 RE K+E ++ +++ +K ++ K+ ++++ ++++++++++++R+R+R+RKR Sbjct: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRW 161 Query: 150 ----KRKKKRKKKKKKTGNEGAK 168 +RKK+RKK++KK E K Sbjct: 162 AEREERKKERKKERKKERKEKKK 184 Score = 46.2 bits (108), Expect = 1e-05 Identities = 17/68 (25%), Positives = 50/68 (73%), Gaps = 7/68 (10%) Query: 101 QREEKKEKEKEKKKKKKKKKKK-------KKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 QRE K++ ++E+ K + +++K+ + +K +++ K+ ++++ R+R+R+R+R+R++ Sbjct: 85 QRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERER 144 Query: 154 KRKKKKKK 161 +R++++K+ Sbjct: 145 QRQRERKR 152 Score = 45.8 bits (107), Expect = 2e-05 Identities = 15/60 (25%), Positives = 49/60 (81%), Gaps = 1/60 (1%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKK-KKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 RE K++++E+K++ + +++ +K +++ K+ ++++ ++R+R+R+R+R+R+++R++K++ Sbjct: 94 RERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRE 153 Score = 45.4 bits (106), Expect = 2e-05 Identities = 13/61 (21%), Positives = 48/61 (78%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 QRE + + E+E + +++ + +++ ++ ++K+++++K++ R+R+R+R+ +R+ +R+++++ Sbjct: 24 QRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQ 83 Query: 161 K 161 + Sbjct: 84 R 84 Score = 45.1 bits (105), Expect = 3e-05 Identities = 16/65 (24%), Positives = 50/65 (76%), Gaps = 1/65 (1%) Query: 97 HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 H R+ +EKE+E ++K++ ++++++++ +++ +++++++++R+RKR+ R+R K R Sbjct: 43 HRERDRQTDREKERE-RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101 Query: 157 KKKKK 161 +++K+ Sbjct: 102 RERKR 106 Score = 44.7 bits (104), Expect = 4e-05 Identities = 13/64 (20%), Positives = 51/64 (79%), Gaps = 1/64 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK-KKRKRKRKRKRKRKKKRKKKK 159 +RE +KE++++++++++ +++ ++++++++++++K++ ++R + R R+RKR+ R +++ Sbjct: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114 Query: 160 KKTG 163 + G Sbjct: 115 NRKG 118 Score = 43.9 bits (102), Expect = 7e-05 Identities = 16/73 (21%), Positives = 55/73 (75%), Gaps = 6/73 (8%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKK---RKRKRKRKRKRKK---KR 155 RE+++E++KE+ ++++++++ +++ ++++++++++++K+ R+R + R R+RK+ + Sbjct: 52 REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111 Query: 156 KKKKKKTGNEGAK 168 +++ +K G E K Sbjct: 112 RERNRKGGRERDK 124 Score = 43.5 bits (101), Expect = 9e-05 Identities = 16/61 (26%), Positives = 46/61 (75%), Gaps = 1/61 (1%) Query: 101 QREEKKEKEKE-KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 QR+ ++E E+E ++++++++++++K++ +++ K + +++KR+ R R+R RK R++ K Sbjct: 65 QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDK 124 Query: 160 K 160 + Sbjct: 125 Q 125 Score = 42.7 bits (99), Expect = 1e-04 Identities = 11/61 (18%), Positives = 48/61 (78%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE + E+E +++ + +++ ++ ++K+++++K++ ++R+R+R+ +R+ +++R+++++ Sbjct: 26 ERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQ 85 Query: 161 K 161 + Sbjct: 86 R 86 Score = 42.7 bits (99), Expect = 1e-04 Identities = 13/64 (20%), Positives = 51/64 (79%), Gaps = 3/64 (4%) Query: 101 QREEKKEKEKE---KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 QR+ +E++++ +K+++++K++ ++++++++ +++ +++++R+R+R+RKR+ ++R K Sbjct: 39 QRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK 98 Query: 158 KKKK 161 + + Sbjct: 99 DRDR 102 Score = 42.4 bits (98), Expect = 2e-04 Identities = 12/61 (19%), Positives = 46/61 (75%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 QRE K+E ++ K+ ++++ ++++++ + +++ + +++ + R+R R+ R+++++R+K++ Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63 Query: 161 K 161 + Sbjct: 64 R 64 Score = 42.4 bits (98), Expect = 2e-04 Identities = 16/66 (24%), Positives = 47/66 (71%), Gaps = 5/66 (7%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKK-----RKRKRKRKRKRKKKR 155 QRE + E+E E+++++++++++K++ +++ K + +++K+ R+R RK R+R K+ Sbjct: 67 QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQT 126 Query: 156 KKKKKK 161 ++++ + Sbjct: 127 ERERDR 132 Score = 42.0 bits (97), Expect = 3e-04 Identities = 10/61 (16%), Positives = 48/61 (78%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+ ++E+E + +++ + +++ + +++ ++ ++K+++++++R R+R+R+R+ +R+ +++ Sbjct: 20 ERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQ 79 Query: 161 K 161 + Sbjct: 80 R 80 Score = 41.6 bits (96), Expect = 3e-04 Identities = 11/61 (18%), Positives = 47/61 (77%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+ ++++E ++ K+ ++++ ++++++ + +++ + +++ R R+R R+ R+K+R+++K+ Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61 Query: 161 K 161 + Sbjct: 62 R 62 Score = 41.2 bits (95), Expect = 4e-04 Identities = 10/61 (16%), Positives = 47/61 (77%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE +++E+E + +++ + +++ + +++ ++ ++K+++R+++R R+R+R+++ +++ + Sbjct: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77 Query: 161 K 161 + Sbjct: 78 R 78 Score = 41.2 bits (95), Expect = 4e-04 Identities = 10/60 (16%), Positives = 47/60 (78%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R+ ++E + E++ + +++ + +++ ++ ++K+++++K+R R+R+R+R+ +++ ++++++ Sbjct: 23 RQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRER 82 Score = 40.4 bits (93), Expect = 7e-04 Identities = 11/61 (18%), Positives = 50/61 (81%), Gaps = 1/61 (1%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKK-KKKRKRKRKRKRKRKKKRKKKKK 160 R ++++ +E+ ++ ++K+++++K++ ++++++++ +++ +R+R+R+R+R++KR+ ++ Sbjct: 36 RHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRE 95 Query: 161 K 161 + Sbjct: 96 R 96 Score = 40.0 bits (92), Expect = 0.001 Identities = 9/60 (15%), Positives = 47/60 (78%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + E ++++++E++ + +++ + +++ + +++ ++ ++K+R+R+++R R+R+++R+ +++ Sbjct: 16 ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75 Score = 39.7 bits (91), Expect = 0.001 Identities = 12/62 (19%), Positives = 47/62 (75%), Gaps = 1/62 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKK-RKRKRKRKRKRKKKRKKKK 159 QRE ++++E++++ +++ K + +++K++ + +++ +K R+R ++ +R+R ++R++++ Sbjct: 79 QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138 Query: 160 KK 161 ++ Sbjct: 139 QR 140 Score = 38.1 bits (87), Expect = 0.004 Identities = 8/59 (13%), Positives = 47/59 (79%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 R ++ E+E++++++++ + +++ + +++ + +++ ++ R+++R+R+++R ++R+++++ Sbjct: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERE 71 >gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [Homo sapiens] Length = 759 Score = 60.5 bits (145), Expect = 7e-10 Identities = 28/68 (41%), Positives = 44/68 (64%) Query: 94 LPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 + L + K ++ +EKKKKKK+KK K K + K +KKKKKK K K+K++ K K Sbjct: 156 IALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKD 215 Query: 154 KRKKKKKK 161 K++++KK+ Sbjct: 216 KKEEEKKE 223 Score = 55.8 bits (133), Expect = 2e-08 Identities = 27/64 (42%), Positives = 41/64 (64%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 Q E+K+K+K++KK K K + K +KKKKKK K+KKK++ K K K++ +KK Sbjct: 169 QEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVID 228 Query: 161 KTGN 164 +GN Sbjct: 229 PSGN 232 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/55 (41%), Positives = 38/55 (69%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ ++KKKKKK+KK K K + K +KK+K+K K K+K+++K K KK++ E Sbjct: 169 QEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKE 223 Score = 50.1 bits (118), Expect = 9e-07 Identities = 22/58 (37%), Positives = 37/58 (63%) Query: 112 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKI 169 K ++ ++KKKKKK+KK K K + K K+K+K+ +++KKK +K K K E ++ Sbjct: 167 KDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEV 224 >gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo sapiens] Length = 690 Score = 60.5 bits (145), Expect = 7e-10 Identities = 28/68 (41%), Positives = 44/68 (64%) Query: 94 LPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 + L + K ++ +EKKKKKK+KK K K + K +KKKKKK K K+K++ K K Sbjct: 87 IALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKD 146 Query: 154 KRKKKKKK 161 K++++KK+ Sbjct: 147 KKEEEKKE 154 Score = 55.8 bits (133), Expect = 2e-08 Identities = 27/64 (42%), Positives = 41/64 (64%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 Q E+K+K+K++KK K K + K +KKKKKK K+KKK++ K K K++ +KK Sbjct: 100 QEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVID 159 Query: 161 KTGN 164 +GN Sbjct: 160 PSGN 163 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/55 (41%), Positives = 38/55 (69%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ ++KKKKKK+KK K K + K +KK+K+K K K+K+++K K KK++ E Sbjct: 100 QEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKE 154 Score = 50.1 bits (118), Expect = 9e-07 Identities = 22/58 (37%), Positives = 37/58 (63%) Query: 112 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKI 169 K ++ ++KKKKKK+KK K K + K K+K+K+ +++KKK +K K K E ++ Sbjct: 98 KDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEV 155 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 59.7 bits (143), Expect = 1e-09 Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 20/87 (22%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKK--------------------KKKKKKKKKK 140 + E+KK+ + K++ KK++KKK K+K KK K++ KK KKK Sbjct: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238 Query: 141 RKRKRKRKRKRKKKRKKKKKKTGNEGA 167 K+K+ R +K KKKR KK +K ++ + Sbjct: 239 EKKKKHRSKKYKKKRSKKSRKESSDSS 265 Score = 55.5 bits (132), Expect = 2e-08 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 20/85 (23%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKK--------------------KKKKKKKKKKKKKK 140 +++ + KE+ KK++KKK K+K KK K++ KK KKK+KKK Sbjct: 183 KKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKK 242 Query: 141 RKRKRKRKRKRKKKRKKKKKKTGNE 165 + R +K K+KR KK +K+ + ++ Sbjct: 243 KHRSKKYKKKRSKKSRKESSDSSSK 267 Score = 49.3 bits (116), Expect = 2e-06 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 23/92 (25%) Query: 93 HLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK-------------- 138 H P+ ++ +++KKKK + K++ KK++KKK K+K Sbjct: 160 HTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDS 219 Query: 139 ---------KKRKRKRKRKRKRKKKRKKKKKK 161 K+R +K K+K K+KK R KK KK Sbjct: 220 ETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKK 251 Score = 47.4 bits (111), Expect = 6e-06 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 19/80 (23%) Query: 101 QREEKKEKEKEKKKKKKK-------------------KKKKKKKKKKKKKKKKKKKKKKR 141 +R +K+ K+K K+K KK K++ KK KKK+KKKK + KK + Sbjct: 191 ERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYK 250 Query: 142 KRKRKRKRKRKKKRKKKKKK 161 K++ K+ RK K+ + Sbjct: 251 KKRSKKSRKESSDSSSKESQ 270 Score = 46.2 bits (108), Expect = 1e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Query: 95 PLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 P + P +E E E+ KK +++KKKK + K++ KKR++K+ KRK KK Sbjct: 150 PKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKY 209 Query: 155 RKKKKKKTGNE 165 + + +E Sbjct: 210 SEDSDSDSDSE 220 Score = 46.2 bits (108), Expect = 1e-05 Identities = 20/55 (36%), Positives = 33/55 (60%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 + + + E K++ KK KKK+KKKK + KK KKK+ K+ RK K+ +++ Sbjct: 218 DSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE 272 Score = 44.7 bits (104), Expect = 4e-05 Identities = 21/58 (36%), Positives = 33/58 (56%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 E+ K + K+ KKK+KKKK + KK KKK+ KK +K+ K ++ + K + K Sbjct: 226 EDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283 Score = 43.5 bits (101), Expect = 9e-05 Identities = 21/62 (33%), Positives = 33/62 (53%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 ++ K + KK KKK+KKKK + KK KKK+ KK +K+ K ++ + K + Sbjct: 225 DEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKA 284 Query: 164 NE 165 E Sbjct: 285 EE 286 Score = 43.5 bits (101), Expect = 9e-05 Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Query: 101 QREEKKEKEKEKKKKKKKKK-KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 +R KK K+KEKKKK + KK KKK+ KK +K+ K+ ++ + K + K ++ Sbjct: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPS 288 Query: 160 KKTGNEGAK 168 G E K Sbjct: 289 DLIGPEAPK 297 Score = 42.0 bits (97), Expect = 3e-04 Identities = 17/62 (27%), Positives = 35/62 (56%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 GL + + + ++ + ++ KK +++KKKK + ++R +KR++K+ KRK Sbjct: 147 GLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKH 206 Query: 158 KK 159 KK Sbjct: 207 KK 208 Score = 41.2 bits (95), Expect = 4e-04 Identities = 19/59 (32%), Positives = 34/59 (57%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E ++ +K KKK+KKKK + KK KKK+ KK +K+ ++ + + + K + K Sbjct: 225 DEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283 Score = 33.1 bits (74), Expect = 0.12 Identities = 15/64 (23%), Positives = 31/64 (48%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 G P+ K E + + ++ KK +++KK+K R ++R +K+++KK Sbjct: 141 GAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKK 200 Query: 158 KKKK 161 K+ Sbjct: 201 SSKR 204 Score = 28.5 bits (62), Expect = 2.9 Identities = 20/118 (16%), Positives = 48/118 (40%), Gaps = 32/118 (27%) Query: 83 IAFCDAGPSLHLPLHGLPQREEKK-----EKEKEKKKKKKKKKKKKK------------- 124 I F A S++ + P +K +KE+E+ ++K+ ++++ Sbjct: 90 IPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLS 149 Query: 125 --------------KKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 + ++ KK + ++K+K R +++ +K++KKK+ K Sbjct: 150 PKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHK 207 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 58.2 bits (139), Expect = 3e-09 Identities = 24/68 (35%), Positives = 52/68 (76%), Gaps = 5/68 (7%) Query: 101 QREEKKEKEKEKKKKKKKKK-----KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155 QRE +E E+E +++++++ K++ +++ +K+++KK++KK+RK++RK K+K +K+R Sbjct: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277 Query: 156 KKKKKKTG 163 + KK+K G Sbjct: 278 EDKKRKWG 285 Score = 53.5 bits (127), Expect = 8e-08 Identities = 17/59 (28%), Positives = 48/59 (81%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G + + ++E+++++ + K++ +++ +K+++KK++KK++KK+++++K++ KR+ KKRK Sbjct: 225 GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283 Score = 48.5 bits (114), Expect = 3e-06 Identities = 20/75 (26%), Positives = 51/75 (68%), Gaps = 7/75 (9%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKK-------KKKKKKKKKKKKKKRKRKRKRKRKRKK 153 +RE + ++E+++++K + +++++ + +++++++ + + K+R R+R RK +RKK Sbjct: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257 Query: 154 KRKKKKKKTGNEGAK 168 +RKK++KK E K Sbjct: 258 ERKKERKKERKEKKK 272 Score = 48.5 bits (114), Expect = 3e-06 Identities = 18/61 (29%), Positives = 49/61 (80%), Gaps = 1/61 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 Q E ++E ++E +++ +++++++ + + K++ +++ +K+ +RK++RK++RKK+RK+KKK Sbjct: 214 QTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKE-ERKKERKKERKKERKEKKK 272 Query: 161 K 161 + Sbjct: 273 E 273 Score = 47.4 bits (111), Expect = 6e-06 Identities = 16/60 (26%), Positives = 46/60 (76%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R+ K+++E+ +K+K+ + + ++K+ + ++ ++++K+K R+R+R R R+R++ R ++K++ Sbjct: 94 RDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKER 153 Score = 44.7 bits (104), Expect = 4e-05 Identities = 14/58 (24%), Positives = 45/58 (77%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 EK EKE+++ +K+ +++++K+K+ + + ++K+ + +R R+R++++ R+++R + +++ Sbjct: 86 EKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRER 143 Score = 44.3 bits (103), Expect = 5e-05 Identities = 13/61 (21%), Positives = 47/61 (77%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R+ +++++E+++K+K+ + + ++K+ + ++ ++++K++ R+R+R R R+++R + ++ Sbjct: 91 ERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE 150 Query: 161 K 161 K Sbjct: 151 K 151 Score = 43.5 bits (101), Expect = 9e-05 Identities = 17/59 (28%), Positives = 45/59 (76%), Gaps = 1/59 (1%) Query: 104 EKKEKEKEKKKKKKKKKKKK-KKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 E++ KEKE + + ++K+ + ++ ++++K+K +++++ R R+R+R R R+K+R+++ +K Sbjct: 101 ERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK 159 Score = 43.1 bits (100), Expect = 1e-04 Identities = 14/65 (21%), Positives = 43/65 (66%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 QRE + +EK +K++ + +K+ +++++K+K+ + + ++K+ + + + K+K +++++ Sbjct: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137 Query: 161 KTGNE 165 G E Sbjct: 138 DRGRE 142 Score = 41.6 bits (96), Expect = 3e-04 Identities = 15/66 (22%), Positives = 48/66 (72%), Gaps = 5/66 (7%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKK-----KKKKKKKKKKKRKRKRKRKRKRKKKR 155 QR+ +KE+E++ +++ +++K + +++++ +++ ++++++R R R ++R R++ R Sbjct: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251 Query: 156 KKKKKK 161 K+++KK Sbjct: 252 KEERKK 257 Score = 41.2 bits (95), Expect = 4e-04 Identities = 15/63 (23%), Positives = 47/63 (74%), Gaps = 1/63 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 QRE + E+E++ ++++K+K+++ ++ + +++ +K+++++ R+R R+RK + +R+++ Sbjct: 164 QRETETERERD-REREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETD 222 Query: 161 KTG 163 + G Sbjct: 223 REG 225 Score = 40.0 bits (92), Expect = 0.001 Identities = 16/76 (21%), Positives = 53/76 (69%), Gaps = 8/76 (10%) Query: 101 QREEKKEKEKE-------KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 +RE + EK+++ ++++ ++++K+K+++ ++ + +++ +K+R+R+ R+R R++ Sbjct: 152 ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211 Query: 154 K-RKKKKKKTGNEGAK 168 K + +++++T EG + Sbjct: 212 KTQTERQRETDREGER 227 Score = 39.7 bits (91), Expect = 0.001 Identities = 14/64 (21%), Positives = 49/64 (76%), Gaps = 3/64 (4%) Query: 101 QREEKKEKEKEKKKKKKKKK---KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 Q E ++++E+EK+K +++++ +++++ + ++K+++++ +K R +R+ + +R++ R++ Sbjct: 118 QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177 Query: 158 KKKK 161 +K+K Sbjct: 178 EKQK 181 Score = 39.7 bits (91), Expect = 0.001 Identities = 14/61 (22%), Positives = 46/61 (75%), Gaps = 3/61 (4%) Query: 101 QREEKKEKEKEKKKKKKKKK---KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 +RE +++EKE++++ +K + ++ + ++++ ++++K+K+++ +R R R+R +K+R++ Sbjct: 142 ERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERER 201 Query: 158 K 158 + Sbjct: 202 Q 202 Score = 39.3 bits (90), Expect = 0.002 Identities = 13/64 (20%), Positives = 49/64 (76%), Gaps = 3/64 (4%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKK---KKKKRKRKRKRKRKRKKKRKK 157 +RE++K +E+E+ + +++++ + ++K+++++ +K + ++ + +R+R R+R+++K+R+ Sbjct: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185 Query: 158 KKKK 161 ++ + Sbjct: 186 ERDR 189 Score = 38.1 bits (87), Expect = 0.004 Identities = 12/57 (21%), Positives = 44/57 (77%), Gaps = 1/57 (1%) Query: 104 EKKEKEKEK-KKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 + +++E+++ ++K +K++ + +K+ +++++K+K+ + R R+++ + +R ++R+K+K Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131 Score = 38.1 bits (87), Expect = 0.004 Identities = 10/59 (16%), Positives = 42/59 (71%) Query: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++++E+ + ++K +K++ + +K+ +++++K+K+ + + + K+ ++ ++++K+ G E Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134 Score = 38.1 bits (87), Expect = 0.004 Identities = 14/63 (22%), Positives = 46/63 (73%), Gaps = 1/63 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R ++KE + + ++K+ + ++ ++++K+K +++++ + R+R+R R R+++++R+ +K Sbjct: 102 RRRKEKETNR-NRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKD 160 Query: 161 KTG 163 + G Sbjct: 161 RDG 163 Score = 37.4 bits (85), Expect = 0.006 Identities = 14/69 (20%), Positives = 49/69 (71%), Gaps = 9/69 (13%) Query: 102 REEKKEKEKEKKKKKKK---------KKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152 RE++ E E++++++K+K +++++ + ++K+++++ +K + +R+ + +R+R Sbjct: 115 REKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD 174 Query: 153 KKRKKKKKK 161 ++R+K+K++ Sbjct: 175 REREKQKER 183 Score = 35.8 bits (81), Expect = 0.018 Identities = 11/61 (18%), Positives = 46/61 (75%), Gaps = 1/61 (1%) Query: 101 QREEKKEKEKEKKKK-KKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 ++E + +++EK+ + ++ ++++K+K +++++ + +++++ R R+++R+R+ +K R ++ Sbjct: 106 EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQR 165 Query: 160 K 160 + Sbjct: 166 E 166 Score = 32.3 bits (72), Expect = 0.20 Identities = 8/65 (12%), Positives = 42/65 (64%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + +++EK+ + ++ ++++K+K +++++ + +++++ + + K + ++ K + +++ Sbjct: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167 Query: 161 KTGNE 165 +T E Sbjct: 168 ETERE 172 Score = 31.2 bits (69), Expect = 0.45 Identities = 11/41 (26%), Positives = 28/41 (68%) Query: 128 KKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 +++++ + ++K +++R R RKR R+++RK+K+ + K Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREK 117 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 58.2 bits (139), Expect = 3e-09 Identities = 27/66 (40%), Positives = 43/66 (65%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 E ++ +K+KKKK+KKK KK KK KK KK + + ++ +K K K+K+ KK K K+K+ Sbjct: 1688 ESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKE 1747 Query: 164 NEGAKI 169 + K+ Sbjct: 1748 KDDQKV 1753 Score = 57.8 bits (138), Expect = 4e-09 Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 9/85 (10%) Query: 93 HLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK---------KKRKR 143 H P + E + KKKKKKK+KKK KK KK KK KK K +K Sbjct: 1670 HSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKH 1729 Query: 144 KRKRKRKRKKKRKKKKKKTGNEGAK 168 K K+K+ +K K K+K+K+ ++ K Sbjct: 1730 KHKKKKSKKNKDKEKEKEKDDQKVK 1754 Score = 52.4 bits (124), Expect = 2e-07 Identities = 40/113 (35%), Positives = 56/113 (49%), Gaps = 20/113 (17%) Query: 51 LSTHSTHSDPSATVLPGSSTHRLKGKIF--HLISIAFCDAGPSLHLPLHGLPQREEKKEK 108 +S + +HS PS + S +H G H S + ++ S ++++KKEK Sbjct: 1653 ISRNQSHSSPSVSP---SRSHSPSGSQTRSHSSSASSAESQDS--------KKKKKKKEK 1701 Query: 109 EKEKKKKKKKKKKKK-------KKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 +K KK KK KK KK +K +K K KKKK KK K K K K K +K K Sbjct: 1702 KKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754 Score = 42.0 bits (97), Expect = 3e-04 Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Query: 98 GLPQREEKKE-KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G P++ K KE ++ K K++K KK K K +K K++K K+ ++ + K + Sbjct: 1052 GTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1111 Query: 157 KKKKKTGNEG 166 K+K+KT +G Sbjct: 1112 KRKRKTEEKG 1121 Score = 32.0 bits (71), Expect = 0.26 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 104 EKKEKEKEKKKKKKKKKKKKK-----KKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 EK ++E++K K K K K+K KK+ K K ++K +R+R + + KK Sbjct: 969 EKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKA 1028 Query: 159 KKKT 162 K++T Sbjct: 1029 KEET 1032 Score = 32.0 bits (71), Expect = 0.26 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 103 EEKKEKEKEKKKKKKKKKKK------KKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 ++K+E++K K K K K+K KK+ K K ++K + + R KK K Sbjct: 970 KDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAK 1029 Query: 157 KKKKKTGN 164 ++ KT N Sbjct: 1030 EETPKTDN 1037 Score = 32.0 bits (71), Expect = 0.26 Identities = 19/67 (28%), Positives = 31/67 (46%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L +EEK +K EK K K +K+K+K ++K K + K + + K K+ Sbjct: 1089 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148 Query: 159 KKKTGNE 165 K + E Sbjct: 1149 KMEPDTE 1155 Score = 29.6 bits (65), Expect = 1.3 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKK---------KKKKKKKRKRKRKRKRKRKKK 154 EK ++ EK K KK K ++ KK K+ +K + + ++ K K Sbjct: 1155 EKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVK 1214 Query: 155 RKKKKKKTGNEGA 167 K ++K TG EG+ Sbjct: 1215 GKVRRKVTGTEGS 1227 Score = 28.9 bits (63), Expect = 2.2 Identities = 19/67 (28%), Positives = 27/67 (40%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 LP R++ E + K +K K+++ K K K K KRK KK+ K Sbjct: 943 LPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVK 1002 Query: 159 KKKTGNE 165 K E Sbjct: 1003 PAKGPQE 1009 Score = 28.5 bits (62), Expect = 2.9 Identities = 17/72 (23%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKR---KRKRKKKRK 156 P++ ++ +K K K+K+ + K K KK +K+RK + + + + Sbjct: 865 PEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 924 Query: 157 KKKKKTGNEGAK 168 K ++ TG E K Sbjct: 925 KSREPTGVEENK 936 Score = 27.7 bits (60), Expect = 5.0 Identities = 16/60 (26%), Positives = 27/60 (45%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P R+E + E K +K K+++ K K K K K+K +K + K ++K Sbjct: 951 PVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEK 1010 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 58.2 bits (139), Expect = 3e-09 Identities = 27/66 (40%), Positives = 43/66 (65%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 E ++ +K+KKKK+KKK KK KK KK KK + + ++ +K K K+K+ KK K K+K+ Sbjct: 1722 ESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKE 1781 Query: 164 NEGAKI 169 + K+ Sbjct: 1782 KDDQKV 1787 Score = 57.8 bits (138), Expect = 4e-09 Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 9/85 (10%) Query: 93 HLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK---------KKRKR 143 H P + E + KKKKKKK+KKK KK KK KK KK K +K Sbjct: 1704 HSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKH 1763 Query: 144 KRKRKRKRKKKRKKKKKKTGNEGAK 168 K K+K+ +K K K+K+K+ ++ K Sbjct: 1764 KHKKKKSKKNKDKEKEKEKDDQKVK 1788 Score = 52.4 bits (124), Expect = 2e-07 Identities = 40/113 (35%), Positives = 56/113 (49%), Gaps = 20/113 (17%) Query: 51 LSTHSTHSDPSATVLPGSSTHRLKGKIF--HLISIAFCDAGPSLHLPLHGLPQREEKKEK 108 +S + +HS PS + S +H G H S + ++ S ++++KKEK Sbjct: 1687 ISRNQSHSSPSVSP---SRSHSPSGSQTRSHSSSASSAESQDS--------KKKKKKKEK 1735 Query: 109 EKEKKKKKKKKKKKK-------KKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 +K KK KK KK KK +K +K K KKKK KK K K K K K +K K Sbjct: 1736 KKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1788 Score = 42.0 bits (97), Expect = 3e-04 Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Query: 98 GLPQREEKKE-KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G P++ K KE ++ K K++K KK K K +K K++K K+ ++ + K + Sbjct: 1086 GTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1145 Query: 157 KKKKKTGNEG 166 K+K+KT +G Sbjct: 1146 KRKRKTEEKG 1155 Score = 32.0 bits (71), Expect = 0.26 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 104 EKKEKEKEKKKKKKKKKKKKK-----KKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 EK ++E++K K K K K+K KK+ K K ++K +R+R + + KK Sbjct: 1003 EKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKA 1062 Query: 159 KKKT 162 K++T Sbjct: 1063 KEET 1066 Score = 32.0 bits (71), Expect = 0.26 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 103 EEKKEKEKEKKKKKKKKKKK------KKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 ++K+E++K K K K K+K KK+ K K ++K + + R KK K Sbjct: 1004 KDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAK 1063 Query: 157 KKKKKTGN 164 ++ KT N Sbjct: 1064 EETPKTDN 1071 Score = 32.0 bits (71), Expect = 0.26 Identities = 19/67 (28%), Positives = 31/67 (46%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L +EEK +K EK K K +K+K+K ++K K + K + + K K+ Sbjct: 1123 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1182 Query: 159 KKKTGNE 165 K + E Sbjct: 1183 KMEPDTE 1189 Score = 29.6 bits (65), Expect = 1.3 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKK---------KKKKKKKRKRKRKRKRKRKKK 154 EK ++ EK K KK K ++ KK K+ +K + + ++ K K Sbjct: 1189 EKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVK 1248 Query: 155 RKKKKKKTGNEGA 167 K ++K TG EG+ Sbjct: 1249 GKVRRKVTGTEGS 1261 Score = 28.9 bits (63), Expect = 2.2 Identities = 19/67 (28%), Positives = 27/67 (40%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 LP R++ E + K +K K+++ K K K K KRK KK+ K Sbjct: 977 LPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVK 1036 Query: 159 KKKTGNE 165 K E Sbjct: 1037 PAKGPQE 1043 Score = 28.5 bits (62), Expect = 2.9 Identities = 17/72 (23%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKR---KRKRKKKRK 156 P++ ++ +K K K+K+ + K K KK +K+RK + + + + Sbjct: 899 PEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSR 958 Query: 157 KKKKKTGNEGAK 168 K ++ TG E K Sbjct: 959 KSREPTGVEENK 970 Score = 28.1 bits (61), Expect = 3.8 Identities = 14/45 (31%), Positives = 27/45 (60%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146 RE+++ KE+EKKK K + K+ + KK +K++++ + K Sbjct: 643 REQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSK 687 Score = 27.7 bits (60), Expect = 5.0 Identities = 16/60 (26%), Positives = 27/60 (45%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P R+E + E K +K K+++ K K K K K+K +K + K ++K Sbjct: 985 PVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEK 1044 Score = 27.3 bits (59), Expect = 6.5 Identities = 14/50 (28%), Positives = 28/50 (56%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR 151 REE +++ K+++KKK K + K+ + KK +++R+R R + Sbjct: 638 REEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSK 687 Score = 26.9 bits (58), Expect = 8.5 Identities = 14/60 (23%), Positives = 31/60 (51%) Query: 94 LPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 +P P ++ ++++ K+++KKK K + K+ + KK +++R+R R K Sbjct: 628 IPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSK 687 >gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo sapiens] Length = 1150 Score = 56.6 bits (135), Expect = 1e-08 Identities = 26/72 (36%), Positives = 48/72 (66%) Query: 87 DAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146 D G ++ L LP++E+KKEK+K+ KK ++K KK+++ + + K K++K K K++ Sbjct: 781 DFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE 840 Query: 147 RKRKRKKKRKKK 158 + +RKK+ K+K Sbjct: 841 DRDERKKEDKRK 852 Score = 37.0 bits (84), Expect = 0.008 Identities = 13/48 (27%), Positives = 36/48 (75%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 EE+KE++KE +K +K++ + +K + K+++++K+++ +++R+R+ Sbjct: 673 EEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720 Score = 37.0 bits (84), Expect = 0.008 Identities = 13/46 (28%), Positives = 36/46 (78%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146 Q+EE+KE EK +K++ + +K + K+++++K++++ ++++R+R+ Sbjct: 675 QKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720 Score = 35.8 bits (81), Expect = 0.018 Identities = 13/53 (24%), Positives = 40/53 (75%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155 ++ K +E+++++K+ +K +K++ + +K + K++++RKR+ + +R+R+++R Sbjct: 668 KQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720 Score = 35.4 bits (80), Expect = 0.024 Identities = 14/56 (25%), Positives = 39/56 (69%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 R K+ K +E+K+++K+ +K +K++ + +K + K++ +RKR+ + +R+++ ++ Sbjct: 665 RLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720 Score = 34.7 bits (78), Expect = 0.041 Identities = 7/47 (14%), Positives = 35/47 (74%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKR 145 +P R++ + +E+E+++++ +++ ++K+ +++ ++++++ R+ +R Sbjct: 311 VPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357 Score = 33.5 bits (75), Expect = 0.091 Identities = 12/55 (21%), Positives = 40/55 (72%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 L ++ + +E+++E+K+ +K +K++ + +K + K+++++KR+ + +R+R+ ++ Sbjct: 666 LTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720 Score = 33.1 bits (74), Expect = 0.12 Identities = 8/54 (14%), Positives = 36/54 (66%) Query: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 + ++ + +K + +++++++++ +++ ++K+ R+R +R+R+R +R ++ Sbjct: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357 Score = 31.6 bits (70), Expect = 0.34 Identities = 8/41 (19%), Positives = 30/41 (73%) Query: 119 KKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 +K + +++++++++ +++ +RKR R+R +R+++R ++ Sbjct: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354 Score = 30.8 bits (68), Expect = 0.59 Identities = 7/44 (15%), Positives = 32/44 (72%) Query: 117 KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +K + +++++++++ +++ ++KR R+R +R+R++ ++ ++ Sbjct: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357 Score = 30.4 bits (67), Expect = 0.77 Identities = 11/70 (15%), Positives = 38/70 (54%) Query: 92 LHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR 151 L P+ + Q + + + + + + + +K + ++++++++R R+R +RKR Sbjct: 279 LQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKR 338 Query: 152 KKKRKKKKKK 161 ++R ++++ Sbjct: 339 SRERSPRRER 348 Score = 30.0 bits (66), Expect = 1.0 Identities = 9/63 (14%), Positives = 36/63 (57%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 PQ + + + + + +K + +++++++++ R+R +RKR R++ ++++ Sbjct: 289 PQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRER 348 Query: 160 KKT 162 +++ Sbjct: 349 ERS 351 Score = 30.0 bits (66), Expect = 1.0 Identities = 7/41 (17%), Positives = 30/41 (73%) Query: 121 KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +K + +++++++++ +++ +RKR R+R +++R++ ++ Sbjct: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 56.6 bits (135), Expect = 1e-08 Identities = 26/55 (47%), Positives = 36/55 (65%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ K KK+KKK K+KK K+KK+KKKK +K K +K+KKKKKKT + Sbjct: 1356 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410 Score = 56.2 bits (134), Expect = 1e-08 Identities = 27/59 (45%), Positives = 38/59 (64%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E ++ K KK+KKK K+KK K+KK+KKKK KK K +K+KKK+KK ++T Sbjct: 1353 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1411 Score = 52.0 bits (123), Expect = 2e-07 Identities = 24/55 (43%), Positives = 36/55 (65%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 + G Q K +KEK+K K+KK K+KK+KKKK KK K + ++K+K+K+K Sbjct: 1352 VEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1406 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/51 (45%), Positives = 34/51 (66%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 ++ K K++KKK K+KK K+KK+KKKK KK K +K+K+K+KK Sbjct: 1356 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1406 Score = 50.4 bits (119), Expect = 7e-07 Identities = 24/59 (40%), Positives = 37/59 (62%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G+ E + + KK+KKK K+KK K+KK+KKKK KK + + ++K+KKK+K Sbjct: 1348 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1406 Score = 38.1 bits (87), Expect = 0.004 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 12/83 (14%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKK------------KKKKKKKRKRKR 145 G +R++ KEKK K + K + +++ +K K KK+K+K + Sbjct: 1312 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1371 Query: 146 KRKRKRKKKRKKKKKKTGNEGAK 168 ++K K KK++KKK KK + ++ Sbjct: 1372 RKKDKEKKEKKKKAKKASTKDSE 1394 Score = 30.8 bits (68), Expect = 0.59 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 3/74 (4%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK---K 154 G R+ K ++ + + KKKKK + + +K K K KR + K Sbjct: 1265 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVK 1324 Query: 155 RKKKKKKTGNEGAK 168 KK K G++GAK Sbjct: 1325 EKKGKGSLGSQGAK 1338 Score = 29.3 bits (64), Expect = 1.7 Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 118 KKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 ++++KK K+ +K + +KRK + R + KKKKK EG + Sbjct: 1248 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1298 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 56.6 bits (135), Expect = 1e-08 Identities = 26/55 (47%), Positives = 36/55 (65%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ K KK+KKK K+KK K+KK+KKKK +K K +K+KKKKKKT + Sbjct: 1395 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449 Score = 56.2 bits (134), Expect = 1e-08 Identities = 27/59 (45%), Positives = 38/59 (64%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E ++ K KK+KKK K+KK K+KK+KKKK KK K +K+KKK+KK ++T Sbjct: 1392 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450 Score = 52.0 bits (123), Expect = 2e-07 Identities = 24/55 (43%), Positives = 36/55 (65%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 + G Q K +KEK+K K+KK K+KK+KKKK KK K + ++K+K+K+K Sbjct: 1391 VEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/51 (45%), Positives = 34/51 (66%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 ++ K K++KKK K+KK K+KK+KKKK KK K +K+K+K+KK Sbjct: 1395 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445 Score = 50.4 bits (119), Expect = 7e-07 Identities = 24/59 (40%), Positives = 37/59 (62%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G+ E + + KK+KKK K+KK K+KK+KKKK KK + + ++K+KKK+K Sbjct: 1387 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445 Score = 38.1 bits (87), Expect = 0.004 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 12/83 (14%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKK------------KKKKKKKRKRKR 145 G +R++ KEKK K + K + +++ +K K KK+K+K + Sbjct: 1351 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1410 Query: 146 KRKRKRKKKRKKKKKKTGNEGAK 168 ++K K KK++KKK KK + ++ Sbjct: 1411 RKKDKEKKEKKKKAKKASTKDSE 1433 Score = 30.8 bits (68), Expect = 0.59 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 3/74 (4%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK---K 154 G R+ K ++ + + KKKKK + + +K K K KR + K Sbjct: 1304 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVK 1363 Query: 155 RKKKKKKTGNEGAK 168 KK K G++GAK Sbjct: 1364 EKKGKGSLGSQGAK 1377 Score = 29.3 bits (64), Expect = 1.7 Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 118 KKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 ++++KK K+ +K + +KRK + R + KKKKK EG + Sbjct: 1287 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1337 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 56.6 bits (135), Expect = 1e-08 Identities = 26/55 (47%), Positives = 36/55 (65%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ K KK+KKK K+KK K+KK+KKKK +K K +K+KKKKKKT + Sbjct: 1432 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1486 Score = 56.2 bits (134), Expect = 1e-08 Identities = 27/59 (45%), Positives = 38/59 (64%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E ++ K KK+KKK K+KK K+KK+KKKK KK K +K+KKK+KK ++T Sbjct: 1429 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1487 Score = 52.0 bits (123), Expect = 2e-07 Identities = 24/55 (43%), Positives = 36/55 (65%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 + G Q K +KEK+K K+KK K+KK+KKKK KK K + ++K+K+K+K Sbjct: 1428 VEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1482 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/51 (45%), Positives = 34/51 (66%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 ++ K K++KKK K+KK K+KK+KKKK KK K +K+K+K+KK Sbjct: 1432 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1482 Score = 50.4 bits (119), Expect = 7e-07 Identities = 24/59 (40%), Positives = 37/59 (62%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G+ E + + KK+KKK K+KK K+KK+KKKK KK + + ++K+KKK+K Sbjct: 1424 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1482 Score = 38.1 bits (87), Expect = 0.004 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 12/83 (14%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKK------------KKKKKKKRKRKR 145 G +R++ KEKK K + K + +++ +K K KK+K+K + Sbjct: 1388 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1447 Query: 146 KRKRKRKKKRKKKKKKTGNEGAK 168 ++K K KK++KKK KK + ++ Sbjct: 1448 RKKDKEKKEKKKKAKKASTKDSE 1470 Score = 30.8 bits (68), Expect = 0.59 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 3/74 (4%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK---K 154 G R+ K ++ + + KKKKK + + +K K K KR + K Sbjct: 1341 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVK 1400 Query: 155 RKKKKKKTGNEGAK 168 KK K G++GAK Sbjct: 1401 EKKGKGSLGSQGAK 1414 Score = 29.3 bits (64), Expect = 1.7 Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 118 KKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 ++++KK K+ +K + +KRK + R + KKKKK EG + Sbjct: 1324 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1374 >gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo sapiens] Length = 1411 Score = 56.6 bits (135), Expect = 1e-08 Identities = 26/55 (47%), Positives = 36/55 (65%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ K KK+KKK K+KK K+KK+KKKK +K K +K+KKKKKKT + Sbjct: 1355 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1409 Score = 56.2 bits (134), Expect = 1e-08 Identities = 27/59 (45%), Positives = 38/59 (64%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E ++ K KK+KKK K+KK K+KK+KKKK KK K +K+KKK+KK ++T Sbjct: 1352 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1410 Score = 52.0 bits (123), Expect = 2e-07 Identities = 24/55 (43%), Positives = 36/55 (65%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 + G Q K +KEK+K K+KK K+KK+KKKK KK K + ++K+K+K+K Sbjct: 1351 VEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1405 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/51 (45%), Positives = 34/51 (66%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 ++ K K++KKK K+KK K+KK+KKKK KK K +K+K+K+KK Sbjct: 1355 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1405 Score = 50.4 bits (119), Expect = 7e-07 Identities = 24/59 (40%), Positives = 37/59 (62%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G+ E + + KK+KKK K+KK K+KK+KKKK KK + + ++K+KKK+K Sbjct: 1347 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1405 Score = 38.1 bits (87), Expect = 0.004 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 12/83 (14%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKK------------KKKKKKKRKRKR 145 G +R++ KEKK K + K + +++ +K K KK+K+K + Sbjct: 1311 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1370 Query: 146 KRKRKRKKKRKKKKKKTGNEGAK 168 ++K K KK++KKK KK + ++ Sbjct: 1371 RKKDKEKKEKKKKAKKASTKDSE 1393 Score = 30.8 bits (68), Expect = 0.59 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 3/74 (4%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK---K 154 G R+ K ++ + + KKKKK + + +K K K KR + K Sbjct: 1264 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVK 1323 Query: 155 RKKKKKKTGNEGAK 168 KK K G++GAK Sbjct: 1324 EKKGKGSLGSQGAK 1337 Score = 29.3 bits (64), Expect = 1.7 Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 118 KKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 ++++KK K+ +K + +KRK + R + KKKKK EG + Sbjct: 1247 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1297 >gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo sapiens] Length = 1450 Score = 56.6 bits (135), Expect = 1e-08 Identities = 26/55 (47%), Positives = 36/55 (65%) Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 ++ K KK+KKK K+KK K+KK+KKKK +K K +K+KKKKKKT + Sbjct: 1394 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1448 Score = 56.2 bits (134), Expect = 1e-08 Identities = 27/59 (45%), Positives = 38/59 (64%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E ++ K KK+KKK K+KK K+KK+KKKK KK K +K+KKK+KK ++T Sbjct: 1391 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1449 Score = 52.0 bits (123), Expect = 2e-07 Identities = 24/55 (43%), Positives = 36/55 (65%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 + G Q K +KEK+K K+KK K+KK+KKKK KK K + ++K+K+K+K Sbjct: 1390 VEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1444 Score = 52.0 bits (123), Expect = 2e-07 Identities = 23/51 (45%), Positives = 34/51 (66%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 ++ K K++KKK K+KK K+KK+KKKK KK K +K+K+K+KK Sbjct: 1394 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1444 Score = 50.4 bits (119), Expect = 7e-07 Identities = 24/59 (40%), Positives = 37/59 (62%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 G+ E + + KK+KKK K+KK K+KK+KKKK KK + + ++K+KKK+K Sbjct: 1386 GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1444 Score = 38.1 bits (87), Expect = 0.004 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 12/83 (14%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKK------------KKKKKKKRKRKR 145 G +R++ KEKK K + K + +++ +K K KK+K+K + Sbjct: 1350 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1409 Query: 146 KRKRKRKKKRKKKKKKTGNEGAK 168 ++K K KK++KKK KK + ++ Sbjct: 1410 RKKDKEKKEKKKKAKKASTKDSE 1432 Score = 30.8 bits (68), Expect = 0.59 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 3/74 (4%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK---K 154 G R+ K ++ + + KKKKK + + +K K K KR + K Sbjct: 1303 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVK 1362 Query: 155 RKKKKKKTGNEGAK 168 KK K G++GAK Sbjct: 1363 EKKGKGSLGSQGAK 1376 Score = 29.3 bits (64), Expect = 1.7 Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 118 KKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 ++++KK K+ +K + +KRK + R + KKKKK EG + Sbjct: 1286 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1336 >gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapiens] Length = 729 Score = 55.5 bits (132), Expect = 2e-08 Identities = 26/59 (44%), Positives = 41/59 (69%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 EE KE + K+KKKKKKK K++++K KKK K KK K K + K +R+R+++R + ++ Sbjct: 642 EEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRE 700 Score = 54.7 bits (130), Expect = 4e-08 Identities = 25/65 (38%), Positives = 42/65 (64%) Query: 95 PLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 P + +E K KEKKKKKKK K++++K KKK K KK K K+ ++ +R+R+++ Sbjct: 637 PKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPP 696 Query: 155 RKKKK 159 R +++ Sbjct: 697 RSRER 701 Score = 53.5 bits (127), Expect = 8e-08 Identities = 25/63 (39%), Positives = 41/63 (65%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 +E E+ KE K K+KKKKKKK K++++K KKK K +K K K + K +++R++++ Sbjct: 638 KESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPR 697 Query: 163 GNE 165 E Sbjct: 698 SRE 700 Score = 53.1 bits (126), Expect = 1e-07 Identities = 24/64 (37%), Positives = 44/64 (68%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 GL + K+ E+ K+ K K+KKKKKKK K++++K KKK + +K K K + K++R++ Sbjct: 631 GLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRR 690 Query: 158 KKKK 161 ++++ Sbjct: 691 RQQR 694 Score = 52.8 bits (125), Expect = 1e-07 Identities = 23/60 (38%), Positives = 42/60 (70%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E K+ K K+KKKKKKK K++++K KKK K KK K ++ ++ +R+R+++ + +++T Sbjct: 643 EGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERT 702 Score = 48.9 bits (115), Expect = 2e-06 Identities = 23/66 (34%), Positives = 42/66 (63%) Query: 96 LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155 L GL E ++ E+ K+ K K+KKKKKKK K++++K KK+ + +K K K + K Sbjct: 627 LFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKE 686 Query: 156 KKKKKK 161 ++++++ Sbjct: 687 ERRRRQ 692 Score = 43.5 bits (101), Expect = 9e-05 Identities = 25/76 (32%), Positives = 39/76 (51%) Query: 90 PSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149 P L LP L + E+ K+ ++ K+ K K+KKKKKKK K + ++ K+ Sbjct: 612 PKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKK 671 Query: 150 KRKKKRKKKKKKTGNE 165 K K K+ K K++ E Sbjct: 672 KSKHKKSKDKEEGKEE 687 Score = 42.0 bits (97), Expect = 3e-04 Identities = 20/47 (42%), Positives = 29/47 (61%) Query: 120 KKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEG 166 K+ ++ K+ K K+KKKKK+K K + ++ KKK K KK K EG Sbjct: 638 KESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEG 684 Score = 37.4 bits (85), Expect = 0.006 Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 121 KKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 K+ ++ K+ K K+KKKK+K+ ++ + K KK+ K KK E K Sbjct: 638 KESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGK 685 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 55.5 bits (132), Expect = 2e-08 Identities = 23/68 (33%), Positives = 47/68 (69%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE +KE+EKEK++ K K + K+++K ++K K+K +++++ K K + K K+K + K+K Sbjct: 398 EREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 457 Query: 161 KTGNEGAK 168 + + +K Sbjct: 458 EREKDRSK 465 Score = 54.7 bits (130), Expect = 4e-08 Identities = 23/61 (37%), Positives = 49/61 (80%), Gaps = 1/61 (1%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRK-RKRKRKRKRKKKRKKKKK 160 +E+ +EKE+E++K+++K+K++ K K + K+++K ++K K K R+R+R+++ +K R K+K+ Sbjct: 391 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE 450 Query: 161 K 161 K Sbjct: 451 K 451 Score = 53.5 bits (127), Expect = 8e-08 Identities = 22/72 (30%), Positives = 49/72 (68%) Query: 97 HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 H +R++ +EK KEK++ K+K ++K+++++K+++K+K++ K K + K + K + K K K Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431 Query: 157 KKKKKTGNEGAK 168 ++++ E K Sbjct: 432 DREREREKEHEK 443 Score = 53.1 bits (126), Expect = 1e-07 Identities = 22/67 (32%), Positives = 45/67 (67%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 RE+++E+EKE++K+K++ K K + K+++K ++K K+K + + + K K + K K+K++ Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454 Query: 162 TGNEGAK 168 E K Sbjct: 455 KEKEREK 461 Score = 52.8 bits (125), Expect = 1e-07 Identities = 21/65 (32%), Positives = 45/65 (69%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E ++EKE+EK+K++ K K + K+++K ++K K+K +++ + K K + K+K K++ K Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 455 Query: 161 KTGNE 165 + E Sbjct: 456 EKERE 460 Score = 52.8 bits (125), Expect = 1e-07 Identities = 20/61 (32%), Positives = 46/61 (75%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E +K++EK+K+K ++++++K+ +K + K+K+K++ K+K + K + K +K++K KK + Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478 Query: 162 T 162 T Sbjct: 479 T 479 Score = 52.4 bits (124), Expect = 2e-07 Identities = 21/65 (32%), Positives = 44/65 (67%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E +KEKE+ K K + K+++K ++K K+K ++++++K+ K + K K K + K K+++K Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461 Query: 161 KTGNE 165 E Sbjct: 462 DRSKE 466 Score = 52.4 bits (124), Expect = 2e-07 Identities = 20/61 (32%), Positives = 46/61 (75%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R++++EK++EK K+K ++++++K+ +K + K+K+K++ K K + K + K +++KK KK Sbjct: 417 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 476 Query: 162 T 162 + Sbjct: 477 S 477 Score = 51.6 bits (122), Expect = 3e-07 Identities = 25/73 (34%), Positives = 48/73 (65%), Gaps = 5/73 (6%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK-----KKR 155 +RE+++EKEKE+ K K + K+++K ++K K+K ++++++K K + K K K K+R Sbjct: 400 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459 Query: 156 KKKKKKTGNEGAK 168 +K + K +E K Sbjct: 460 EKDRSKEIDEKRK 472 Score = 51.2 bits (121), Expect = 4e-07 Identities = 20/59 (33%), Positives = 45/59 (76%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 +RE+ +EK+KEK ++++++K+ +K + K+K+K++ K+K++ K + K +++KK KK + Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478 Score = 50.4 bits (119), Expect = 7e-07 Identities = 18/62 (29%), Positives = 44/62 (70%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P ++ K +E+ K + + + K+K ++K K+K++ K+K R+++R+R+++R+K++++ K Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413 Query: 160 KK 161 K Sbjct: 414 NK 415 Score = 50.4 bits (119), Expect = 7e-07 Identities = 21/67 (31%), Positives = 46/67 (68%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 +K++ +EK K+K++ K+K ++K+++++K+++K+K++ K K + K + K + K K+K Sbjct: 375 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 434 Query: 164 NEGAKIH 170 E K H Sbjct: 435 REREKEH 441 Score = 50.1 bits (118), Expect = 9e-07 Identities = 21/62 (33%), Positives = 48/62 (77%), Gaps = 3/62 (4%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKK---KKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 ++ KE+EK+++K K+K ++++++K+ +K K+K+K++ K+++R++ R ++ +KRKK Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474 Query: 159 KK 160 KK Sbjct: 475 KK 476 Score = 49.3 bits (116), Expect = 2e-06 Identities = 21/77 (27%), Positives = 49/77 (63%), Gaps = 9/77 (11%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKR---------KRKRKR 151 +RE +KE EK++ K+K+K++ K+K+++K + K+ +K+KK K+ R +R R Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493 Query: 152 KKKRKKKKKKTGNEGAK 168 ++R++++ ++ + + Sbjct: 494 SRERRRRRSRSSSRSPR 510 Score = 48.1 bits (113), Expect = 4e-06 Identities = 20/64 (31%), Positives = 41/64 (64%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 RE ++EKE EK + K+K+K++ K+K+++K + K+ +K++K K+ R R ++ + Sbjct: 433 REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 492 Query: 162 TGNE 165 + E Sbjct: 493 SSRE 496 Score = 47.8 bits (112), Expect = 5e-06 Identities = 19/71 (26%), Positives = 49/71 (69%), Gaps = 6/71 (8%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKK------KKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 Q++ ++ K KK+ K ++++K + K+K ++K K+K++ +++ R+++R+R+K+ Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404 Query: 155 RKKKKKKTGNE 165 R+K+K++ N+ Sbjct: 405 REKEKERGKNK 415 Score = 47.8 bits (112), Expect = 5e-06 Identities = 17/61 (27%), Positives = 44/61 (72%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R + +E+ K + + + K+K ++K K+K++ K+K ++++R+R+++R+++K+R K K Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 416 Query: 161 K 161 + Sbjct: 417 R 417 Score = 47.4 bits (111), Expect = 6e-06 Identities = 20/62 (32%), Positives = 46/62 (74%), Gaps = 2/62 (3%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKK--KKKKKRKRKRKRKRKRKKKRKKKK 159 R ++K K+ ++K K+K++ K+K ++K+++++K +K+K+R + + R ++R+K R+K K Sbjct: 370 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429 Query: 160 KK 161 +K Sbjct: 430 EK 431 Score = 47.4 bits (111), Expect = 6e-06 Identities = 16/64 (25%), Positives = 48/64 (75%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +++ +K+KEK+++++++K+ +K + K+K+K++ K+K+++K + K ++++K K+ + Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481 Query: 161 KTGN 164 ++ N Sbjct: 482 RSYN 485 Score = 46.6 bits (109), Expect = 1e-05 Identities = 16/60 (26%), Positives = 44/60 (73%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 RE +K + + + K+K ++K K+K++ K+K ++K+++R+++R+++++R K + + K++ Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421 Score = 46.6 bits (109), Expect = 1e-05 Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 101 QREEKKEKEKEKKKKK---KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 ++E+ KEKE+EK + K +K+KK KK + + ++ + R+R+R+R R R Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509 Query: 158 KKKKT 162 + KT Sbjct: 510 RTSKT 514 Score = 45.8 bits (107), Expect = 2e-05 Identities = 16/60 (26%), Positives = 44/60 (73%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R ++K K ++K K+K++ K+K ++K+++++K+++++++R + + R K+R+K ++K Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 427 Score = 45.4 bits (106), Expect = 2e-05 Identities = 15/61 (24%), Positives = 45/61 (73%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R + + + + K+K ++K K+K++ K+K ++K+++++++R+++++R + K R K+++ Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 422 Query: 161 K 161 K Sbjct: 423 K 423 Score = 44.7 bits (104), Expect = 4e-05 Identities = 17/67 (25%), Positives = 43/67 (64%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E+ +E+E+EK+ +K + K+K+K++ K+K+++K + K+ ++++K K+ R R + Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488 Query: 162 TGNEGAK 168 ++ Sbjct: 489 RSRSSSR 495 Score = 43.1 bits (100), Expect = 1e-04 Identities = 16/65 (24%), Positives = 37/65 (56%) Query: 97 HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 H +R + K + + + + ++K +++ K KK+ K ++++K + + + KRK R+ Sbjct: 323 HSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE 382 Query: 157 KKKKK 161 K K+K Sbjct: 383 KIKEK 387 Score = 42.7 bits (99), Expect = 1e-04 Identities = 15/60 (25%), Positives = 37/60 (61%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R + + ++K +++ K KK+ K ++++K + + + KRK R++ ++K+R K+K + Sbjct: 336 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 395 Score = 40.4 bits (93), Expect = 7e-04 Identities = 13/61 (21%), Positives = 33/61 (54%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R + K + K ++K+ + K + + + + ++K R+R + +KR K R+++K + Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 368 Query: 162 T 162 + Sbjct: 369 S 369 Score = 40.4 bits (93), Expect = 7e-04 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 39/100 (39%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKR---------------KRKR 145 ++E +K+++KEK+K++ K+K+++K + K+ +K+KK KK R R+R Sbjct: 438 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 497 Query: 146 KRKRKR------------------------KKKRKKKKKK 161 +R+R R + K+ KK++K Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537 Score = 40.0 bits (92), Expect = 0.001 Identities = 13/58 (22%), Positives = 31/58 (53%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 + + K + K + + + + ++K +++ K KK+ + R+R++ R R R K+K Sbjct: 321 KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 378 Score = 39.7 bits (91), Expect = 0.001 Identities = 14/61 (22%), Positives = 32/61 (52%) Query: 108 KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGA 167 + K + K + + + + ++K +++ K KKR + R+R++ R + + K+K E Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384 Query: 168 K 168 K Sbjct: 385 K 385 Score = 39.3 bits (90), Expect = 0.002 Identities = 14/68 (20%), Positives = 34/68 (50%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R K + K+ + K + + + + ++K +++ K +KR + R+R++ + R + K Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376 Query: 162 TGNEGAKI 169 + KI Sbjct: 377 RKDTREKI 384 Score = 38.9 bits (89), Expect = 0.002 Identities = 15/60 (25%), Positives = 30/60 (50%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E K + + + K + K ++K+ + K + + R R R++ R+R K KK+ K+ Sbjct: 302 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 361 Score = 37.7 bits (86), Expect = 0.005 Identities = 14/62 (22%), Positives = 35/62 (56%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE+ + KE ++K+KK KK + + ++ + +++R+R+ + + + K K+ Sbjct: 458 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 517 Query: 161 KT 162 K+ Sbjct: 518 KS 519 Score = 37.0 bits (84), Expect = 0.008 Identities = 11/60 (18%), Positives = 31/60 (51%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 + K ++K+ + K + + + + ++K +++ K +KR + R+R+K R + + Sbjct: 315 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 374 Score = 37.0 bits (84), Expect = 0.008 Identities = 13/65 (20%), Positives = 32/65 (49%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R ++ + + + K K+K + + + KK KK+ K + +R+++R + Sbjct: 496 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMR 555 Query: 161 KTGNE 165 K+ N+ Sbjct: 556 KSSND 560 Score = 36.6 bits (83), Expect = 0.011 Identities = 10/57 (17%), Positives = 32/57 (56%) Query: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 K + K ++K+ + K + + + + ++K ++R + +KR + ++R+K + ++ Sbjct: 315 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 371 Score = 34.7 bits (78), Expect = 0.041 Identities = 13/66 (19%), Positives = 30/66 (45%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R + + + K K+K + + + KK KK++K + +R+R++ +K Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557 Query: 161 KTGNEG 166 +G Sbjct: 558 SNDRDG 563 Score = 33.9 bits (76), Expect = 0.069 Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 12/71 (16%) Query: 103 EEKKEKEKEKK---------KKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK---RK 150 +EK++K+K+ + ++ + +++++++ + + + K KRK R R Sbjct: 468 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 527 Query: 151 RKKKRKKKKKK 161 R KK KK++K+ Sbjct: 528 RNKKDKKREKE 538 Score = 33.9 bits (76), Expect = 0.069 Identities = 13/66 (19%), Positives = 32/66 (48%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P+ KK+K++EK++ +++++++ +K + K++ K K K+ K+ Sbjct: 525 PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584 Query: 160 KKTGNE 165 E Sbjct: 585 SSVSKE 590 Score = 33.1 bits (74), Expect = 0.12 Identities = 13/67 (19%), Positives = 35/67 (52%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++++K+EKE++ +++++++ +K + K+K +K K K K+ K Sbjct: 530 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 589 Query: 161 KTGNEGA 167 + ++ A Sbjct: 590 EVDDKDA 596 Score = 32.7 bits (73), Expect = 0.15 Identities = 13/60 (21%), Positives = 31/60 (51%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R + K ++K + + + KK KK++K++ ++R+R+R ++ + K+K Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 566 Score = 32.3 bits (72), Expect = 0.20 Identities = 14/60 (23%), Positives = 30/60 (50%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R K K K + + + KK KK++K++ +++++ + RK + K+K +K Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569 Score = 30.0 bits (66), Expect = 1.0 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK---RKRKRKRKKKRKKKKKKT 162 K +++ + + + KK KK++K++ ++++R+R RK R K K +K T Sbjct: 513 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 572 Score = 30.0 bits (66), Expect = 1.0 Identities = 13/55 (23%), Positives = 26/55 (47%) Query: 110 KEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164 K K + + + KK KK++K++ +++ + + RK R K+K N Sbjct: 516 KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 570 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 55.5 bits (132), Expect = 2e-08 Identities = 23/68 (33%), Positives = 47/68 (69%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE +KE+EKEK++ K K + K+++K ++K K+K +++++ K K + K K+K + K+K Sbjct: 282 EREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 341 Query: 161 KTGNEGAK 168 + + +K Sbjct: 342 EREKDRSK 349 Score = 54.7 bits (130), Expect = 4e-08 Identities = 23/61 (37%), Positives = 49/61 (80%), Gaps = 1/61 (1%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRK-RKRKRKRKRKKKRKKKKK 160 +E+ +EKE+E++K+++K+K++ K K + K+++K ++K K K R+R+R+++ +K R K+K+ Sbjct: 275 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE 334 Query: 161 K 161 K Sbjct: 335 K 335 Score = 53.5 bits (127), Expect = 8e-08 Identities = 22/72 (30%), Positives = 49/72 (68%) Query: 97 HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 H +R++ +EK KEK++ K+K ++K+++++K+++K+K++ K K + K + K + K K K Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315 Query: 157 KKKKKTGNEGAK 168 ++++ E K Sbjct: 316 DREREREKEHEK 327 Score = 53.1 bits (126), Expect = 1e-07 Identities = 22/67 (32%), Positives = 45/67 (67%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 RE+++E+EKE++K+K++ K K + K+++K ++K K+K + + + K K + K K+K++ Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338 Query: 162 TGNEGAK 168 E K Sbjct: 339 KEKEREK 345 Score = 52.8 bits (125), Expect = 1e-07 Identities = 21/65 (32%), Positives = 45/65 (69%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E ++EKE+EK+K++ K K + K+++K ++K K+K +++ + K K + K+K K++ K Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 339 Query: 161 KTGNE 165 + E Sbjct: 340 EKERE 344 Score = 52.8 bits (125), Expect = 1e-07 Identities = 20/61 (32%), Positives = 46/61 (75%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E +K++EK+K+K ++++++K+ +K + K+K+K++ K+K + K + K +K++K KK + Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362 Query: 162 T 162 T Sbjct: 363 T 363 Score = 52.4 bits (124), Expect = 2e-07 Identities = 21/65 (32%), Positives = 44/65 (67%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E +KEKE+ K K + K+++K ++K K+K ++++++K+ K + K K K + K K+++K Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345 Query: 161 KTGNE 165 E Sbjct: 346 DRSKE 350 Score = 52.4 bits (124), Expect = 2e-07 Identities = 20/61 (32%), Positives = 46/61 (75%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R++++EK++EK K+K ++++++K+ +K + K+K+K++ K K + K + K +++KK KK Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 360 Query: 162 T 162 + Sbjct: 361 S 361 Score = 51.6 bits (122), Expect = 3e-07 Identities = 25/73 (34%), Positives = 48/73 (65%), Gaps = 5/73 (6%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK-----KKR 155 +RE+++EKEKE+ K K + K+++K ++K K+K ++++++K K + K K K K+R Sbjct: 284 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343 Query: 156 KKKKKKTGNEGAK 168 +K + K +E K Sbjct: 344 EKDRSKEIDEKRK 356 Score = 51.2 bits (121), Expect = 4e-07 Identities = 20/59 (33%), Positives = 45/59 (76%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 +RE+ +EK+KEK ++++++K+ +K + K+K+K++ K+K++ K + K +++KK KK + Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362 Score = 50.4 bits (119), Expect = 7e-07 Identities = 18/62 (29%), Positives = 44/62 (70%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P ++ K +E+ K + + + K+K ++K K+K++ K+K R+++R+R+++R+K++++ K Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297 Query: 160 KK 161 K Sbjct: 298 NK 299 Score = 50.4 bits (119), Expect = 7e-07 Identities = 21/67 (31%), Positives = 46/67 (68%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 +K++ +EK K+K++ K+K ++K+++++K+++K+K++ K K + K + K + K K+K Sbjct: 259 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 318 Query: 164 NEGAKIH 170 E K H Sbjct: 319 REREKEH 325 Score = 50.1 bits (118), Expect = 9e-07 Identities = 21/62 (33%), Positives = 48/62 (77%), Gaps = 3/62 (4%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKK---KKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 ++ KE+EK+++K K+K ++++++K+ +K K+K+K++ K+++R++ R ++ +KRKK Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358 Query: 159 KK 160 KK Sbjct: 359 KK 360 Score = 49.3 bits (116), Expect = 2e-06 Identities = 21/77 (27%), Positives = 49/77 (63%), Gaps = 9/77 (11%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKR---------KRKRKR 151 +RE +KE EK++ K+K+K++ K+K+++K + K+ +K+KK K+ R +R R Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377 Query: 152 KKKRKKKKKKTGNEGAK 168 ++R++++ ++ + + Sbjct: 378 SRERRRRRSRSSSRSPR 394 Score = 48.1 bits (113), Expect = 4e-06 Identities = 20/64 (31%), Positives = 41/64 (64%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 RE ++EKE EK + K+K+K++ K+K+++K + K+ +K++K K+ R R ++ + Sbjct: 317 REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 376 Query: 162 TGNE 165 + E Sbjct: 377 SSRE 380 Score = 47.8 bits (112), Expect = 5e-06 Identities = 19/71 (26%), Positives = 49/71 (69%), Gaps = 6/71 (8%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKK------KKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 Q++ ++ K KK+ K ++++K + K+K ++K K+K++ +++ R+++R+R+K+ Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288 Query: 155 RKKKKKKTGNE 165 R+K+K++ N+ Sbjct: 289 REKEKERGKNK 299 Score = 47.8 bits (112), Expect = 5e-06 Identities = 17/61 (27%), Positives = 44/61 (72%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R + +E+ K + + + K+K ++K K+K++ K+K ++++R+R+++R+++K+R K K Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 300 Query: 161 K 161 + Sbjct: 301 R 301 Score = 47.4 bits (111), Expect = 6e-06 Identities = 20/62 (32%), Positives = 46/62 (74%), Gaps = 2/62 (3%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKK--KKKKKRKRKRKRKRKRKKKRKKKK 159 R ++K K+ ++K K+K++ K+K ++K+++++K +K+K+R + + R ++R+K R+K K Sbjct: 254 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313 Query: 160 KK 161 +K Sbjct: 314 EK 315 Score = 47.4 bits (111), Expect = 6e-06 Identities = 16/64 (25%), Positives = 48/64 (75%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +++ +K+KEK+++++++K+ +K + K+K+K++ K+K+++K + K ++++K K+ + Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365 Query: 161 KTGN 164 ++ N Sbjct: 366 RSYN 369 Score = 46.6 bits (109), Expect = 1e-05 Identities = 16/60 (26%), Positives = 44/60 (73%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 RE +K + + + K+K ++K K+K++ K+K ++K+++R+++R+++++R K + + K++ Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305 Score = 46.6 bits (109), Expect = 1e-05 Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 101 QREEKKEKEKEKKKKK---KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 ++E+ KEKE+EK + K +K+KK KK + + ++ + R+R+R+R R R Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393 Query: 158 KKKKT 162 + KT Sbjct: 394 RTSKT 398 Score = 45.8 bits (107), Expect = 2e-05 Identities = 16/60 (26%), Positives = 44/60 (73%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R ++K K ++K K+K++ K+K ++K+++++K+++++++R + + R K+R+K ++K Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 311 Score = 45.4 bits (106), Expect = 2e-05 Identities = 15/61 (24%), Positives = 45/61 (73%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R + + + + K+K ++K K+K++ K+K ++K+++++++R+++++R + K R K+++ Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE 306 Query: 161 K 161 K Sbjct: 307 K 307 Score = 44.7 bits (104), Expect = 4e-05 Identities = 17/67 (25%), Positives = 43/67 (64%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E+ +E+E+EK+ +K + K+K+K++ K+K+++K + K+ ++++K K+ R R + Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372 Query: 162 TGNEGAK 168 ++ Sbjct: 373 RSRSSSR 379 Score = 43.1 bits (100), Expect = 1e-04 Identities = 16/65 (24%), Positives = 37/65 (56%) Query: 97 HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 H +R + K + + + + ++K +++ K KK+ K ++++K + + + KRK R+ Sbjct: 207 HSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE 266 Query: 157 KKKKK 161 K K+K Sbjct: 267 KIKEK 271 Score = 42.7 bits (99), Expect = 1e-04 Identities = 15/60 (25%), Positives = 37/60 (61%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R + + ++K +++ K KK+ K ++++K + + + KRK R++ ++K+R K+K + Sbjct: 220 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 279 Score = 40.4 bits (93), Expect = 7e-04 Identities = 13/61 (21%), Positives = 33/61 (54%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R + K + K ++K+ + K + + + + ++K R+R + +KR K R+++K + Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 252 Query: 162 T 162 + Sbjct: 253 S 253 Score = 40.4 bits (93), Expect = 7e-04 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 39/100 (39%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKR---------------KRKR 145 ++E +K+++KEK+K++ K+K+++K + K+ +K+KK KK R R+R Sbjct: 322 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 381 Query: 146 KRKRKR------------------------KKKRKKKKKK 161 +R+R R + K+ KK++K Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421 Score = 40.0 bits (92), Expect = 0.001 Identities = 13/58 (22%), Positives = 31/58 (53%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 + + K + K + + + + ++K +++ K KK+ + R+R++ R R R K+K Sbjct: 205 KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 262 Score = 39.7 bits (91), Expect = 0.001 Identities = 14/61 (22%), Positives = 32/61 (52%) Query: 108 KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGA 167 + K + K + + + + ++K +++ K KKR + R+R++ R + + K+K E Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268 Query: 168 K 168 K Sbjct: 269 K 269 Score = 39.3 bits (90), Expect = 0.002 Identities = 14/68 (20%), Positives = 34/68 (50%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R K + K+ + K + + + + ++K +++ K +KR + R+R++ + R + K Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260 Query: 162 TGNEGAKI 169 + KI Sbjct: 261 RKDTREKI 268 Score = 38.9 bits (89), Expect = 0.002 Identities = 15/60 (25%), Positives = 30/60 (50%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E K + + + K + K ++K+ + K + + R R R++ R+R K KK+ K+ Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245 Score = 37.7 bits (86), Expect = 0.005 Identities = 14/62 (22%), Positives = 35/62 (56%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +RE+ + KE ++K+KK KK + + ++ + +++R+R+ + + + K K+ Sbjct: 342 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 401 Query: 161 KT 162 K+ Sbjct: 402 KS 403 Score = 37.0 bits (84), Expect = 0.008 Identities = 11/60 (18%), Positives = 31/60 (51%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 + K ++K+ + K + + + + ++K +++ K +KR + R+R+K R + + Sbjct: 199 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 258 Score = 37.0 bits (84), Expect = 0.008 Identities = 13/65 (20%), Positives = 32/65 (49%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R ++ + + + K K+K + + + KK KK+ K + +R+++R + Sbjct: 380 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMR 439 Query: 161 KTGNE 165 K+ N+ Sbjct: 440 KSSND 444 Score = 36.6 bits (83), Expect = 0.011 Identities = 10/57 (17%), Positives = 32/57 (56%) Query: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 K + K ++K+ + K + + + + ++K ++R + +KR + ++R+K + ++ Sbjct: 199 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 255 Score = 34.7 bits (78), Expect = 0.041 Identities = 13/66 (19%), Positives = 30/66 (45%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R + + + K K+K + + + KK KK++K + +R+R++ +K Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441 Query: 161 KTGNEG 166 +G Sbjct: 442 SNDRDG 447 Score = 33.9 bits (76), Expect = 0.069 Identities = 16/71 (22%), Positives = 38/71 (53%), Gaps = 12/71 (16%) Query: 103 EEKKEKEKEKK---------KKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK---RK 150 +EK++K+K+ + ++ + +++++++ + + + K KRK R R Sbjct: 352 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 411 Query: 151 RKKKRKKKKKK 161 R KK KK++K+ Sbjct: 412 RNKKDKKREKE 422 Score = 33.9 bits (76), Expect = 0.069 Identities = 13/66 (19%), Positives = 32/66 (48%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P+ KK+K++EK++ +++++++ +K + K++ K K K+ K+ Sbjct: 409 PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468 Query: 160 KKTGNE 165 E Sbjct: 469 SSVSKE 474 Score = 33.1 bits (74), Expect = 0.12 Identities = 13/67 (19%), Positives = 35/67 (52%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++++K+EKE++ +++++++ +K + K+K +K K K K+ K Sbjct: 414 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 473 Query: 161 KTGNEGA 167 + ++ A Sbjct: 474 EVDDKDA 480 Score = 32.7 bits (73), Expect = 0.15 Identities = 13/60 (21%), Positives = 31/60 (51%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R + K ++K + + + KK KK++K++ ++R+R+R ++ + K+K Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 450 Score = 32.3 bits (72), Expect = 0.20 Identities = 14/60 (23%), Positives = 30/60 (50%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 R K K K + + + KK KK++K++ +++++ + RK + K+K +K Sbjct: 394 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 453 Score = 30.0 bits (66), Expect = 1.0 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK---RKRKRKRKKKRKKKKKKT 162 K +++ + + + KK KK++K++ ++++R+R RK R K K +K T Sbjct: 397 KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNST 456 Score = 30.0 bits (66), Expect = 1.0 Identities = 13/55 (23%), Positives = 26/55 (47%) Query: 110 KEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164 K K + + + KK KK++K++ +++ + + RK R K+K N Sbjct: 400 KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 454 >gi|167614488 TBC1 domain family, member 10B [Homo sapiens] Length = 808 Score = 55.1 bits (131), Expect = 3e-08 Identities = 18/63 (28%), Positives = 54/63 (85%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 G + K+EKE++K++K+++K++K+++K+++K++K+++K++K + K++++R++++K+ + Sbjct: 716 GSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQ 775 Query: 158 KKK 160 +K Sbjct: 776 GRK 778 Score = 54.7 bits (130), Expect = 4e-08 Identities = 25/80 (31%), Positives = 60/80 (75%), Gaps = 3/80 (3%) Query: 90 PSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149 PSL P KE K++K+++K++K+++K++K+++K+++K++K++ K++++R+ Sbjct: 703 PSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKERE- 761 Query: 150 KRKKKRKKKKKKTGNEGAKI 169 K++K+R+K++KK +G K+ Sbjct: 762 KQEKERQKQEKKA--QGRKL 779 Score = 52.0 bits (123), Expect = 2e-07 Identities = 17/59 (28%), Positives = 51/59 (86%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 + +K+EKE++K++K+++K+++K++K+++K++K+++K++K ++K+++K + +K ++K Sbjct: 726 KERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRK 784 Score = 51.6 bits (122), Expect = 3e-07 Identities = 18/69 (26%), Positives = 57/69 (82%), Gaps = 3/69 (4%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK--- 157 +++EK+ +++EK+++K++K+++K+++K++K+++K++K+++++ K ++K+++K + +K Sbjct: 722 RKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSL 781 Query: 158 KKKKTGNEG 166 ++K G G Sbjct: 782 RRKADGPPG 790 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 55.1 bits (131), Expect = 3e-08 Identities = 26/61 (42%), Positives = 44/61 (72%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++EEK +KE+ KK+ KK+ KK++KK+ KK+ KK+ K+ +K +K ++K KK +K+ K Sbjct: 670 KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK 729 Query: 161 K 161 K Sbjct: 730 K 730 Score = 54.3 bits (129), Expect = 5e-08 Identities = 29/69 (42%), Positives = 46/69 (66%), Gaps = 1/69 (1%) Query: 100 PQREE-KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 P++EE KKE +KE KK++KK+ KK+ KK+ K+ KK+ KK+ K++ K++ K KK KK Sbjct: 675 PKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKK 734 Query: 159 KKKTGNEGA 167 K + + Sbjct: 735 LPKDAKKSS 743 Score = 52.4 bits (124), Expect = 2e-07 Identities = 24/62 (38%), Positives = 47/62 (75%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P ++E+K K++E KK+ KK+ KK++KK+ KK+ KK+ K+ K++ K++ K++ K+++K+ Sbjct: 668 PIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKE 727 Query: 160 KK 161 K Sbjct: 728 PK 729 Score = 52.0 bits (123), Expect = 2e-07 Identities = 26/67 (38%), Positives = 45/67 (67%) Query: 95 PLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154 P + ++E+K +KE+K KK++ KK+ KK+ KK++KK+ KK+ K++ K +K KK Sbjct: 656 PKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKK 715 Query: 155 RKKKKKK 161 +KK+ K Sbjct: 716 EEKKEVK 722 Score = 51.6 bits (122), Expect = 3e-07 Identities = 25/60 (41%), Positives = 43/60 (71%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 ++E K K ++KK++K+K KK+ KK+ K KK++K KK + K++ K++ KK+ KK+ KK Sbjct: 639 KKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKK 698 Score = 51.6 bits (122), Expect = 3e-07 Identities = 26/67 (38%), Positives = 45/67 (67%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 + E K++EKEK KK+ KK+ K KK++K KK++ KK+ K++ K++ K++ K++ KK+ Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704 Query: 162 TGNEGAK 168 E K Sbjct: 705 PPKEVKK 711 Score = 51.6 bits (122), Expect = 3e-07 Identities = 26/68 (38%), Positives = 48/68 (70%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++ +K+E +KE KK+ KK++KK+ KK+ KK+ K+ KK+ K++ K++ K+++K KK+ Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEI 732 Query: 161 KTGNEGAK 168 K + AK Sbjct: 733 KKLPKDAK 740 Score = 51.2 bits (121), Expect = 4e-07 Identities = 25/66 (37%), Positives = 48/66 (72%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 +K+EK K+++ KK+ KK+ KK++KK+ KK+ KK+ ++ K++ K++ KK+ KK++K+ Sbjct: 670 KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK 729 Query: 164 NEGAKI 169 E K+ Sbjct: 730 KEIKKL 735 Score = 49.7 bits (117), Expect = 1e-06 Identities = 27/71 (38%), Positives = 48/71 (67%), Gaps = 3/71 (4%) Query: 101 QREEKKEKEKEKKKKKKK---KKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 ++EEK++ +KE KK+ K KK++K KK++ KK+ KK+ KK+ K++ K++ K++ K+ Sbjct: 649 KKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKE 708 Query: 158 KKKKTGNEGAK 168 KK+ E K Sbjct: 709 VKKEVKKEEKK 719 Score = 48.9 bits (115), Expect = 2e-06 Identities = 28/76 (36%), Positives = 49/76 (64%), Gaps = 10/76 (13%) Query: 103 EEKKEKEKEKKK----------KKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152 ++K+EKEK KK+ KK++K KK++ KK+ KK+ KK++KK+ K++ K++ K Sbjct: 648 DKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK 707 Query: 153 KKRKKKKKKTGNEGAK 168 + +K+ KK+ E K Sbjct: 708 EVKKEVKKEEKKEVKK 723 Score = 48.5 bits (114), Expect = 3e-06 Identities = 23/65 (35%), Positives = 43/65 (66%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E K + E +K++K+K KK+ KK+ K KK++K KK+ +K +K +K+++K+ KK Sbjct: 639 KKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKK 698 Query: 161 KTGNE 165 + E Sbjct: 699 EVKKE 703 Score = 47.8 bits (112), Expect = 5e-06 Identities = 26/72 (36%), Positives = 47/72 (65%), Gaps = 3/72 (4%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKK---KKKKRKRKRKRKRKRKKKRK 156 P+ ++K +KE K K + KK++K+K KK+ KK+ K KK+++ +K + K++ KK+ K Sbjct: 630 PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIK 689 Query: 157 KKKKKTGNEGAK 168 K++KK + K Sbjct: 690 KEEKKEPKKEVK 701 Score = 45.1 bits (105), Expect = 3e-05 Identities = 24/57 (42%), Positives = 36/57 (63%) Query: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 K + KEK KK+ K K + KK++K+K KK+ KK+ K K++ K KK+ KK+ K Sbjct: 629 KPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVK 685 Score = 44.7 bits (104), Expect = 4e-05 Identities = 27/79 (34%), Positives = 42/79 (53%) Query: 90 PSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149 PS P + EK+ + + K K+K KK+ K K + KK++K+K KK K++ K Sbjct: 608 PSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKT 667 Query: 150 KRKKKRKKKKKKTGNEGAK 168 KK+ K KK++ E K Sbjct: 668 PIKKEEKPKKEEVKKEVKK 686 Score = 44.3 bits (103), Expect = 5e-05 Identities = 24/62 (38%), Positives = 41/62 (66%), Gaps = 1/62 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKK-KKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 ++EEKKE +KE KK+ K+ KK+ KK++KK+ KK++K+ K++ K+ K +K + Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748 Query: 160 KK 161 K Sbjct: 749 AK 750 Score = 43.5 bits (101), Expect = 9e-05 Identities = 26/64 (40%), Positives = 37/64 (57%), Gaps = 3/64 (4%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK---KKRKRKRKRKRKRKKKRK 156 P +E KKE +KE+KK+ KK++K+ KK+ KK K KK + K+ K K KK + Sbjct: 705 PPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEE 764 Query: 157 KKKK 160 KK Sbjct: 765 SVKK 768 Score = 42.7 bits (99), Expect = 1e-04 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 3/72 (4%) Query: 100 PQREEKKE---KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 P++E KKE KE +K+ KK++KK+ KK++K+ KK+ KK K +K +K Sbjct: 696 PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAAL 755 Query: 157 KKKKKTGNEGAK 168 K K E K Sbjct: 756 KPKVPKKEESVK 767 Score = 38.1 bits (87), Expect = 0.004 Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 10/76 (13%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKK------KKKK----KKKKKKKKRKRKRKRKRK 150 ++EEKKE +KE+K+ KK+ KK K KK + KK K K KK+ K+ Sbjct: 714 KKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAA 773 Query: 151 RKKKRKKKKKKTGNEG 166 K K K K K EG Sbjct: 774 GKPKEKGKIKVIKKEG 789 Score = 37.4 bits (85), Expect = 0.006 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKK-----KKKKKRKRKRKRKRKRKK 153 +P +EE + E +K+ K K K+K KK+ K KK++K K K++ +K K Sbjct: 607 VPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDK 666 Query: 154 KRKKKKKKTGNEGAK 168 KK++K E K Sbjct: 667 TPIKKEEKPKKEEVK 681 Score = 34.7 bits (78), Expect = 0.041 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 101 QREEKKEKEKE--KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 ++E KKE++KE K++K+ KK+ KK K KK + KK + + K+++ KK Sbjct: 710 KKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKD 769 Query: 159 KKKTGNEGAK 168 G K Sbjct: 770 SVAAGKPKEK 779 Score = 33.5 bits (75), Expect = 0.091 Identities = 18/61 (29%), Positives = 33/61 (54%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E ++E K + +K+ K K K+K KK+ K K + K++ K K K++ KK Sbjct: 604 EKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKK 663 Query: 161 K 161 + Sbjct: 664 E 664 Score = 32.3 bits (72), Expect = 0.20 Identities = 17/60 (28%), Positives = 30/60 (50%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P EK+ KE+ K + +K+ K K K+K KK + + +K +K++ KK+ Sbjct: 600 PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE 659 Score = 29.6 bits (65), Expect = 1.3 Identities = 20/73 (27%), Positives = 33/73 (45%) Query: 87 DAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146 D+ SL LP + +KE ++E + K +K K + K+K KK K K + K Sbjct: 540 DSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETK 599 Query: 147 RKRKRKKKRKKKK 159 K+ K++ Sbjct: 600 PSVTEKEVPSKEE 612 Score = 28.1 bits (61), Expect = 3.8 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 5/74 (6%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK-----RKRKRKKK 154 P + E KEK KK K K + K +K+ K++ K + K + + K+K Sbjct: 577 PPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEK 636 Query: 155 RKKKKKKTGNEGAK 168 KK+ K E K Sbjct: 637 TVKKETKVKPEDKK 650 >gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo sapiens] Length = 956 Score = 55.1 bits (131), Expect = 3e-08 Identities = 22/63 (34%), Positives = 50/63 (79%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L R E++EKEK K++ K+ K++ KKKK+++K+ K+K++++KR++ K K ++++ ++++ Sbjct: 348 LKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEER 407 Query: 159 KKK 161 +K+ Sbjct: 408 RKE 410 Score = 54.7 bits (130), Expect = 4e-08 Identities = 23/67 (34%), Positives = 49/67 (73%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L E+KEK KE+ K+ K++ KKKK+++K+ K+K++++K+++ K K +++R K+ ++K Sbjct: 350 LRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRK 409 Query: 159 KKKTGNE 165 +++ E Sbjct: 410 ERQEALE 416 Score = 54.3 bits (129), Expect = 5e-08 Identities = 26/76 (34%), Positives = 54/76 (71%), Gaps = 8/76 (10%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR--------K 152 + E K+ KE+ KKKK+++K+ K+K++++K++K +K+K +K++ K +R+++R + Sbjct: 361 KEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLE 420 Query: 153 KKRKKKKKKTGNEGAK 168 +KRKK+++K E K Sbjct: 421 EKRKKEEEKRLREEEK 436 Score = 52.8 bits (125), Expect = 1e-07 Identities = 20/69 (28%), Positives = 52/69 (75%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + ++KKE+EKE K+K++++K++K +K+K +K++ K++++K +++ + +K++K+++K Sbjct: 370 EAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429 Query: 161 KTGNEGAKI 169 + E +I Sbjct: 430 RLREEEKRI 438 Score = 52.4 bits (124), Expect = 2e-07 Identities = 22/62 (35%), Positives = 46/62 (74%) Query: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165 + +EKEK K++ K+ K++ KKKK+++K+ K+K+++ KR++ K K +K+R K++++ + Sbjct: 353 EREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412 Query: 166 GA 167 A Sbjct: 413 EA 414 Score = 52.4 bits (124), Expect = 2e-07 Identities = 21/69 (30%), Positives = 52/69 (75%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + +E KEKE+ +K++K +K+K +K++ K++++K++++ + K + KRK++ +K+ ++++K Sbjct: 377 EEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436 Query: 161 KTGNEGAKI 169 + E A+I Sbjct: 437 RIKAEKAEI 445 Score = 49.3 bits (116), Expect = 2e-06 Identities = 20/60 (33%), Positives = 45/60 (75%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 ++ K E+E+K+K K++ K+ K++ KKKK+++K+ K+K +R+++ K +++K K++ K+ Sbjct: 346 KQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKE 405 Score = 48.9 bits (115), Expect = 2e-06 Identities = 21/68 (30%), Positives = 49/68 (72%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R K+ K + ++++K+K K++ K+ K++ KKKK+++K+ ++++R+ KR++ +K K +K+ Sbjct: 342 ERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQ 401 Query: 161 KTGNEGAK 168 + E K Sbjct: 402 RLKEERRK 409 Score = 48.1 bits (113), Expect = 4e-06 Identities = 17/62 (27%), Positives = 49/62 (79%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L ++E ++++EK++K+K +K++ K++++K++++ + K ++KRK++ +++ + ++KR K Sbjct: 381 LKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440 Query: 159 KK 160 +K Sbjct: 441 EK 442 Score = 46.2 bits (108), Expect = 1e-05 Identities = 19/67 (28%), Positives = 45/67 (67%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 + +++ K+ K + ++++K+K K++ K+ K++ KKKK+ +++ K K +R+K+ K +K+K Sbjct: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397 Query: 162 TGNEGAK 168 + K Sbjct: 398 AEKQRLK 404 Score = 45.4 bits (106), Expect = 2e-05 Identities = 18/61 (29%), Positives = 46/61 (75%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L + +E+ K+ + + ++++K+K K++ K+ K++ KKKK+++++ K K +R++++K +K+ Sbjct: 337 LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE 396 Query: 159 K 159 K Sbjct: 397 K 397 Score = 45.4 bits (106), Expect = 2e-05 Identities = 17/60 (28%), Positives = 46/60 (76%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 QR++++ ++ K + ++++K+K K++ K+ K++ KKKK++ K ++++R+ K+++ +K+K Sbjct: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397 Score = 42.7 bits (99), Expect = 1e-04 Identities = 21/67 (31%), Positives = 45/67 (67%), Gaps = 5/67 (7%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKK-----KKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155 ++ EK EKEK +K++ K++++K+++ K ++K+KK+++K+ + + KR + K + R Sbjct: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447 Query: 156 KKKKKKT 162 +K KT Sbjct: 448 FFQKPKT 454 Score = 41.2 bits (95), Expect = 4e-04 Identities = 27/118 (22%), Positives = 63/118 (53%), Gaps = 5/118 (4%) Query: 53 THSTHSDPSATVLPGSSTHRLKGKIFHLISIAFCDAGPSLHLPLHGLPQREEKKEK--EK 110 +HS+ S PS+T P K H + F + P + + EK + ++ Sbjct: 283 SHSSLSSPSSTSSPEGPPAPPKQ---HSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQR 339 Query: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 ++++ K+ K + ++++K+K K++ K+ K+ +K+K + K K++++++K+ +E K Sbjct: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397 >gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 54.7 bits (130), Expect = 4e-08 Identities = 22/65 (33%), Positives = 49/65 (75%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E+KK++ ++ K+KK+ K++KKK ++K K +++ KKK++ ++K+ ++ +RKK+ ++ K++ Sbjct: 54 EDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ 113 Query: 163 GNEGA 167 E A Sbjct: 114 EEEAA 118 Score = 51.6 bits (122), Expect = 3e-07 Identities = 20/67 (29%), Positives = 48/67 (71%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 ++KK E +K+KK+ K++KKK ++K K +++ KKK+++ K+K + + ++K++ + K+++ Sbjct: 55 DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114 Query: 163 GNEGAKI 169 A++ Sbjct: 115 EEAAAQM 121 Score = 49.7 bits (117), Expect = 1e-06 Identities = 17/62 (27%), Positives = 51/62 (82%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P+ ++K+ ++ ++KK+ K++KKK ++K K +++ KKK+++++K+ ++ +RK+++++ K++ Sbjct: 53 PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112 Query: 160 KK 161 ++ Sbjct: 113 QE 114 Score = 49.7 bits (117), Expect = 1e-06 Identities = 20/72 (27%), Positives = 49/72 (68%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L + KKE ++ KKK ++K K +++ KKK++++KKK ++++RK++ ++ ++++++ Sbjct: 60 LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119 Query: 159 KKKTGNEGAKIH 170 + K E ++H Sbjct: 120 QMKEKEESIQLH 131 Score = 48.9 bits (115), Expect = 2e-06 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 1/65 (1%) Query: 105 KKEKEKEKKKKKKK-KKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 KKE K + KKK+ + K+KK+ K++KKK ++K K + +K++ + KKK +++++K Sbjct: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105 Query: 164 NEGAK 168 E AK Sbjct: 106 EEQAK 110 Score = 48.9 bits (115), Expect = 2e-06 Identities = 17/60 (28%), Positives = 48/60 (80%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 ++++ E +K KK+ K++KKK ++K K +++ KKK++++K+K + + ++K++++ K+++++ Sbjct: 56 KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115 Score = 48.1 bits (113), Expect = 4e-06 Identities = 24/72 (33%), Positives = 46/72 (63%), Gaps = 5/72 (6%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKK-----KKKKRKRKRKRKRKRKKKR 155 ++E K E +KK+ + K+KK+ K++KKK ++K K KKK+ + K+K + + +KK+ Sbjct: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105 Query: 156 KKKKKKTGNEGA 167 +++ K+ E A Sbjct: 106 EEQAKRQQEEEA 117 Score = 47.8 bits (112), Expect = 5e-06 Identities = 19/63 (30%), Positives = 44/63 (69%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L ++E + ++KKK+ + K+KK+ K++KKK ++K K ++ +K++ + K+K + +++ Sbjct: 43 LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102 Query: 159 KKK 161 KK+ Sbjct: 103 KKQ 105 Score = 46.6 bits (109), Expect = 1e-05 Identities = 22/60 (36%), Positives = 39/60 (65%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P+ + K +KE K + KKK+ + K+KK+ K++KKK + K K + + K+K++ +KKK Sbjct: 37 PKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96 Score = 45.8 bits (107), Expect = 2e-05 Identities = 19/69 (27%), Positives = 48/69 (69%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E KK+ E++ K +++ KKK++++KKK +++++KK++++ KR+++ + + K K++ + Sbjct: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129 Query: 162 TGNEGAKIH 170 E + H Sbjct: 130 LHQEAWERH 138 Score = 43.1 bits (100), Expect = 1e-04 Identities = 20/67 (29%), Positives = 40/67 (59%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +++ K K++ K + KKK+ + K+KK+ K++KKK ++ + + +KK+ ++KKK Sbjct: 38 KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKH 97 Query: 162 TGNEGAK 168 E K Sbjct: 98 QEEERKK 104 Score = 42.7 bits (99), Expect = 1e-04 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 10/80 (12%) Query: 99 LPQREEK----------KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148 LP +EK KE+ K+ K KK+ K + KKK+ + K+KK+ K ++K+ Sbjct: 17 LPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76 Query: 149 RKRKKKRKKKKKKTGNEGAK 168 ++ K ++ KKK E K Sbjct: 77 EEKVKAEEESKKKEEEEKKK 96 Score = 42.0 bits (97), Expect = 3e-04 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKK-KKKKRKRKRKRKRKRKKKRKKKK 159 +R + K KK+ K + KKK+ + K+KK+ K +KKK + K K + + KKK +++K Sbjct: 35 ERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEK 94 Query: 160 KKTGNEGAK 168 KK E K Sbjct: 95 KKHQEEERK 103 Score = 38.1 bits (87), Expect = 0.004 Identities = 18/68 (26%), Positives = 43/68 (63%), Gaps = 4/68 (5%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK----RKRKRKRKKKRK 156 + E KK++E+EKKK +++++KK++++ K++++++ + K K + + +R RK Sbjct: 83 EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK 142 Query: 157 KKKKKTGN 164 + + K N Sbjct: 143 ELRSKNQN 150 Score = 35.8 bits (81), Expect = 0.018 Identities = 13/67 (19%), Positives = 46/67 (68%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + ++K+E+EK+K +++++KK++++ K++++++ + K+K + + + ++ +K+ Sbjct: 85 ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKEL 144 Query: 161 KTGNEGA 167 ++ N+ A Sbjct: 145 RSKNQNA 151 Score = 33.5 bits (75), Expect = 0.091 Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 18/88 (20%) Query: 99 LPQREEKKEKEKEKKKKKKKKKK------------------KKKKKKKKKKKKKKKKKKK 140 +P +K +EK K+K K KK+ K + KKK+ Sbjct: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60 Query: 141 RKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 KRK++ K +KK+ ++K K E K Sbjct: 61 EDDKRKKEDKERKKKDEEKVKAEEESKK 88 >gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 54.7 bits (130), Expect = 4e-08 Identities = 22/65 (33%), Positives = 49/65 (75%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 E+KK++ ++ K+KK+ K++KKK ++K K +++ KKK++ ++K+ ++ +RKK+ ++ K++ Sbjct: 54 EDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ 113 Query: 163 GNEGA 167 E A Sbjct: 114 EEEAA 118 Score = 51.6 bits (122), Expect = 3e-07 Identities = 20/67 (29%), Positives = 48/67 (71%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 ++KK E +K+KK+ K++KKK ++K K +++ KKK+++ K+K + + ++K++ + K+++ Sbjct: 55 DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114 Query: 163 GNEGAKI 169 A++ Sbjct: 115 EEAAAQM 121 Score = 49.7 bits (117), Expect = 1e-06 Identities = 17/62 (27%), Positives = 51/62 (82%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P+ ++K+ ++ ++KK+ K++KKK ++K K +++ KKK+++++K+ ++ +RK+++++ K++ Sbjct: 53 PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112 Query: 160 KK 161 ++ Sbjct: 113 QE 114 Score = 49.7 bits (117), Expect = 1e-06 Identities = 20/72 (27%), Positives = 49/72 (68%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L + KKE ++ KKK ++K K +++ KKK++++KKK ++++RK++ ++ ++++++ Sbjct: 60 LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119 Query: 159 KKKTGNEGAKIH 170 + K E ++H Sbjct: 120 QMKEKEESIQLH 131 Score = 48.9 bits (115), Expect = 2e-06 Identities = 24/65 (36%), Positives = 43/65 (66%), Gaps = 1/65 (1%) Query: 105 KKEKEKEKKKKKKK-KKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 KKE K + KKK+ + K+KK+ K++KKK ++K K + +K++ + KKK +++++K Sbjct: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105 Query: 164 NEGAK 168 E AK Sbjct: 106 EEQAK 110 Score = 48.9 bits (115), Expect = 2e-06 Identities = 17/60 (28%), Positives = 48/60 (80%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 ++++ E +K KK+ K++KKK ++K K +++ KKK++++K+K + + ++K++++ K+++++ Sbjct: 56 KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115 Score = 48.1 bits (113), Expect = 4e-06 Identities = 24/72 (33%), Positives = 46/72 (63%), Gaps = 5/72 (6%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKK-----KKKKRKRKRKRKRKRKKKR 155 ++E K E +KK+ + K+KK+ K++KKK ++K K KKK+ + K+K + + +KK+ Sbjct: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105 Query: 156 KKKKKKTGNEGA 167 +++ K+ E A Sbjct: 106 EEQAKRQQEEEA 117 Score = 47.8 bits (112), Expect = 5e-06 Identities = 19/63 (30%), Positives = 44/63 (69%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L ++E + ++KKK+ + K+KK+ K++KKK ++K K ++ +K++ + K+K + +++ Sbjct: 43 LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102 Query: 159 KKK 161 KK+ Sbjct: 103 KKQ 105 Score = 46.6 bits (109), Expect = 1e-05 Identities = 22/60 (36%), Positives = 39/60 (65%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P+ + K +KE K + KKK+ + K+KK+ K++KKK + K K + + K+K++ +KKK Sbjct: 37 PKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96 Score = 45.8 bits (107), Expect = 2e-05 Identities = 19/69 (27%), Positives = 48/69 (69%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +E KK+ E++ K +++ KKK++++KKK +++++KK++++ KR+++ + + K K++ + Sbjct: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129 Query: 162 TGNEGAKIH 170 E + H Sbjct: 130 LHQEAWERH 138 Score = 43.1 bits (100), Expect = 1e-04 Identities = 20/67 (29%), Positives = 40/67 (59%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 +++ K K++ K + KKK+ + K+KK+ K++KKK ++ + + +KK+ ++KKK Sbjct: 38 KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKH 97 Query: 162 TGNEGAK 168 E K Sbjct: 98 QEEERKK 104 Score = 42.7 bits (99), Expect = 1e-04 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 10/80 (12%) Query: 99 LPQREEK----------KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148 LP +EK KE+ K+ K KK+ K + KKK+ + K+KK+ K ++K+ Sbjct: 17 LPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76 Query: 149 RKRKKKRKKKKKKTGNEGAK 168 ++ K ++ KKK E K Sbjct: 77 EEKVKAEEESKKKEEEEKKK 96 Score = 42.0 bits (97), Expect = 3e-04 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKK-KKKKRKRKRKRKRKRKKKRKKKK 159 +R + K KK+ K + KKK+ + K+KK+ K +KKK + K K + + KKK +++K Sbjct: 35 ERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEK 94 Query: 160 KKTGNEGAK 168 KK E K Sbjct: 95 KKHQEEERK 103 Score = 38.1 bits (87), Expect = 0.004 Identities = 18/68 (26%), Positives = 43/68 (63%), Gaps = 4/68 (5%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK----RKRKRKRKKKRK 156 + E KK++E+EKKK +++++KK++++ K++++++ + K K + + +R RK Sbjct: 83 EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK 142 Query: 157 KKKKKTGN 164 + + K N Sbjct: 143 ELRSKNQN 150 Score = 35.8 bits (81), Expect = 0.018 Identities = 13/67 (19%), Positives = 46/67 (68%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + ++K+E+EK+K +++++KK++++ K++++++ + K+K + + + ++ +K+ Sbjct: 85 ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKEL 144 Query: 161 KTGNEGA 167 ++ N+ A Sbjct: 145 RSKNQNA 151 Score = 33.5 bits (75), Expect = 0.091 Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 18/88 (20%) Query: 99 LPQREEKKEKEKEKKKKKKKKKK------------------KKKKKKKKKKKKKKKKKKK 140 +P +K +EK K+K K KK+ K + KKK+ Sbjct: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60 Query: 141 RKRKRKRKRKRKKKRKKKKKKTGNEGAK 168 KRK++ K +KK+ ++K K E K Sbjct: 61 EDDKRKKEDKERKKKDEEKVKAEEESKK 88 >gi|11067749 bromodomain containing protein 3 [Homo sapiens] Length = 726 Score = 54.7 bits (130), Expect = 4e-08 Identities = 28/79 (35%), Positives = 48/79 (60%) Query: 91 SLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 ++H L L Q K K+K++KK+K+KKKK K+K+K+K K K +++KK + ++ + Sbjct: 472 AVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQ 531 Query: 151 RKKKRKKKKKKTGNEGAKI 169 +KK KK T G ++ Sbjct: 532 QKKAPAKKANSTTTAGRQL 550 Score = 46.2 bits (108), Expect = 1e-05 Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Query: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKK 159 P + KK+KEK K+K+KKKK K+K+K+K K K +++KK K ++ ++K+ +K Sbjct: 484 PVNKPKKKKEK-KEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANS 542 Query: 160 KKTGNEGAK 168 T K Sbjct: 543 TTTAGRQLK 551 Score = 45.8 bits (107), Expect = 2e-05 Identities = 24/70 (34%), Positives = 44/70 (62%), Gaps = 4/70 (5%) Query: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKK----KKKKKRKRKRKRKRKRKKKRKK 157 +++K++KEKEKKKK K+K+K+K K K +++KK K K+ ++K+ +K + Sbjct: 489 KKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGR 548 Query: 158 KKKKTGNEGA 167 + KK G + + Sbjct: 549 QLKKGGKQAS 558 Score = 45.4 bits (106), Expect = 2e-05 Identities = 25/74 (33%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Query: 95 PLHGLPQREEKKEKEKEKK-KKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153 P++ +++EKKEKEK+KK K+K+K+K K K +++KK K K+ +++K K+ Sbjct: 484 PVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANST 543 Query: 154 KRKKKKKKTGNEGA 167 ++ K G + A Sbjct: 544 TTAGRQLKKGGKQA 557 Score = 45.1 bits (105), Expect = 3e-05 Identities = 24/56 (42%), Positives = 33/56 (58%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156 Q + K E+ + K KKKK+KK+K+KKKK K+K K K K K + +KK K Sbjct: 467 QEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAK 522 Score = 44.7 bits (104), Expect = 4e-05 Identities = 23/60 (38%), Positives = 36/60 (60%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158 L + +E+ + E+ + K KKKK+KK+K+KKKK K K K K K K ++++K K Sbjct: 463 LAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAK 522 Score = 38.9 bits (89), Expect = 0.002 Identities = 20/67 (29%), Positives = 38/67 (56%) Query: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162 EE+ + E +++ K ++ + K KKKK+K+++++K+K K K+K K K K Sbjct: 457 EERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAE 516 Query: 163 GNEGAKI 169 + AK+ Sbjct: 517 EEKKAKV 523 Score = 38.5 bits (88), Expect = 0.003 Identities = 19/64 (29%), Positives = 37/64 (57%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 + ++KK+KEKEK+K K K +++KK K K+ ++KK K+ ++ +K K+ Sbjct: 497 KEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQ 556 Query: 161 KTGN 164 + + Sbjct: 557 ASAS 560 Score = 35.8 bits (81), Expect = 0.018 Identities = 18/68 (26%), Positives = 36/68 (52%) Query: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK 157 G EE++ + +++ K ++ + K KKKK++K K K+K+ ++K+++K Sbjct: 451 GSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEK 510 Query: 158 KKKKTGNE 165 K K E Sbjct: 511 HKVKAEEE 518 Score = 29.6 bits (65), Expect = 1.3 Identities = 15/53 (28%), Positives = 30/53 (56%) Query: 108 KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++K++K KK+ K K++ ++KKK+ +KR + + KK +K+K Sbjct: 638 QKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEK 690 Score = 29.3 bits (64), Expect = 1.7 Identities = 15/64 (23%), Positives = 35/64 (54%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 +R K +K+++K KK+ K K++ ++KKK+ +++ + + K+ +K+ Sbjct: 630 ERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKE 689 Query: 161 KTGN 164 K G+ Sbjct: 690 KPGS 693 Score = 28.1 bits (61), Expect = 3.8 Identities = 14/60 (23%), Positives = 31/60 (51%) Query: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTG 163 +KK+++ KK+ K K++ ++KKK+ +K+ + + +K +K K +G Sbjct: 638 QKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSG 697 Score = 28.1 bits (61), Expect = 3.8 Identities = 15/60 (25%), Positives = 31/60 (51%) Query: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEG 166 +K++ K KK+ K K++ ++KKK+ +K+ + + KK +K+K + G Sbjct: 638 QKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSG 697 Score = 27.3 bits (59), Expect = 6.5 Identities = 14/63 (22%), Positives = 31/63 (49%) Query: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160 ++E+ K K +E+KK K K+ ++KK KK ++ +K ++ +++ Sbjct: 507 EKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEE 566 Query: 161 KTG 163 + G Sbjct: 567 EEG 569 Score = 27.3 bits (59), Expect = 6.5 Identities = 14/54 (25%), Positives = 28/54 (51%) Query: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152 L +++ K KK+ K K++ ++KKK+ +K+ + + +K RK K Sbjct: 637 LQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEK 690 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,493,352 Number of Sequences: 37866 Number of extensions: 547213 Number of successful extensions: 89042 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1591 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 17041 Number of HSP's gapped (non-prelim): 31284 length of query: 170 length of database: 18,247,518 effective HSP length: 95 effective length of query: 75 effective length of database: 14,650,248 effective search space: 1098768600 effective search space used: 1098768600 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.