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Search of human proteins with 118421085
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
(1910 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens] 3831 0.0
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 90 2e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 90 2e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 90 2e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 90 2e-17
gi|163965366 nascent polypeptide-associated complex alpha subuni... 77 2e-13
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 76 4e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 72 5e-12
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 71 1e-11
gi|116284392 mucin 2 precursor [Homo sapiens] 70 2e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 2e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 64 1e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 3e-09
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 60 2e-08
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 57 1e-07
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 57 1e-07
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 57 1e-07
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 57 1e-07
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 57 2e-07
gi|91208420 bassoon protein [Homo sapiens] 56 4e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is... 55 5e-07
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 55 5e-07
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 55 7e-07
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 55 7e-07
gi|54860079 nadrin isoform 1 [Homo sapiens] 54 1e-06
gi|54860105 nadrin isoform 2 [Homo sapiens] 54 1e-06
gi|27735129 hypothetical protein LOC148345 [Homo sapiens] 54 1e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 2e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 2e-06
gi|91982772 mucin 17 [Homo sapiens] 54 2e-06
>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
Length = 1910
Score = 3831 bits (9935), Expect = 0.0
Identities = 1910/1910 (100%), Positives = 1910/1910 (100%)
Query: 1 MACCHKVMLLLDTAGGAARHSRVRRAALRLLTYLSCRFGLARVHWAFKFFDSQGARSRPS 60
MACCHKVMLLLDTAGGAARHSRVRRAALRLLTYLSCRFGLARVHWAFKFFDSQGARSRPS
Sbjct: 1 MACCHKVMLLLDTAGGAARHSRVRRAALRLLTYLSCRFGLARVHWAFKFFDSQGARSRPS 60
Query: 61 RVSDFRELGSRSWEDFEEELEARLEDRAHLPGPAPRATHTHGALMETLLDYQWDRPEITS 120
RVSDFRELGSRSWEDFEEELEARLEDRAHLPGPAPRATHTHGALMETLLDYQWDRPEITS
Sbjct: 61 RVSDFRELGSRSWEDFEEELEARLEDRAHLPGPAPRATHTHGALMETLLDYQWDRPEITS 120
Query: 121 PTKPILRSSGRRLLDVESEAKEAEAALGGLVNAVFLLAPCPHSQRELLQFVSGCEAQAQR 180
PTKPILRSSGRRLLDVESEAKEAEAALGGLVNAVFLLAPCPHSQRELLQFVSGCEAQAQR
Sbjct: 121 PTKPILRSSGRRLLDVESEAKEAEAALGGLVNAVFLLAPCPHSQRELLQFVSGCEAQAQR 180
Query: 181 LPPTPKQVMEKLLPKRVREVMVARKITFYWVDTTEWSKLWESPDHLGYWTVCELLHHGGG 240
LPPTPKQVMEKLLPKRVREVMVARKITFYWVDTTEWSKLWESPDHLGYWTVCELLHHGGG
Sbjct: 181 LPPTPKQVMEKLLPKRVREVMVARKITFYWVDTTEWSKLWESPDHLGYWTVCELLHHGGG 240
Query: 241 TVLPSESFSWDFAQAGEMLLRSGIKLSSEPHLSPWISMLPTDATLNRLLYNSPEYEASFP 300
TVLPSESFSWDFAQAGEMLLRSGIKLSSEPHLSPWISMLPTDATLNRLLYNSPEYEASFP
Sbjct: 241 TVLPSESFSWDFAQAGEMLLRSGIKLSSEPHLSPWISMLPTDATLNRLLYNSPEYEASFP 300
Query: 301 RMEGMLFLPVEAGKEIQETWTVTLEPLAMHQRHFQKPVRIFLKGSVAQWSLPTSSTLGTD 360
RMEGMLFLPVEAGKEIQETWTVTLEPLAMHQRHFQKPVRIFLKGSVAQWSLPTSSTLGTD
Sbjct: 301 RMEGMLFLPVEAGKEIQETWTVTLEPLAMHQRHFQKPVRIFLKGSVAQWSLPTSSTLGTD 360
Query: 361 SWMLGSPEESTATQRLLFQQLVSRLTAEELHLVADVDPGEGRPPITGVISPLSASAMILT 420
SWMLGSPEESTATQRLLFQQLVSRLTAEELHLVADVDPGEGRPPITGVISPLSASAMILT
Sbjct: 361 SWMLGSPEESTATQRLLFQQLVSRLTAEELHLVADVDPGEGRPPITGVISPLSASAMILT 420
Query: 421 VCRTKEAEFQRHVLQTAVADSPRDTASLFSDVVDSILNQTHDSLADTASAASPVPEWAQQ 480
VCRTKEAEFQRHVLQTAVADSPRDTASLFSDVVDSILNQTHDSLADTASAASPVPEWAQQ
Sbjct: 421 VCRTKEAEFQRHVLQTAVADSPRDTASLFSDVVDSILNQTHDSLADTASAASPVPEWAQQ 480
Query: 481 ELGHTTPWSPAVVEKWFPFCNISGASSDLMESFGLLQAASANKEESSKTEGELIHCLAEL 540
ELGHTTPWSPAVVEKWFPFCNISGASSDLMESFGLLQAASANKEESSKTEGELIHCLAEL
Sbjct: 481 ELGHTTPWSPAVVEKWFPFCNISGASSDLMESFGLLQAASANKEESSKTEGELIHCLAEL 540
Query: 541 YQRKSREESTIAHQEDSKKKRGVPRTPVRQKMNTMCRSLKMLNVARLNVKAQKLHPDGSP 600
YQRKSREESTIAHQEDSKKKRGVPRTPVRQKMNTMCRSLKMLNVARLNVKAQKLHPDGSP
Sbjct: 541 YQRKSREESTIAHQEDSKKKRGVPRTPVRQKMNTMCRSLKMLNVARLNVKAQKLHPDGSP 600
Query: 601 DVAGEKGIQKIPSGRTVDKLEDRGRTLRSSKPKDFKTEEELLSYIRENYQKTVATGEIML 660
DVAGEKGIQKIPSGRTVDKLEDRGRTLRSSKPKDFKTEEELLSYIRENYQKTVATGEIML
Sbjct: 601 DVAGEKGIQKIPSGRTVDKLEDRGRTLRSSKPKDFKTEEELLSYIRENYQKTVATGEIML 660
Query: 661 YACARNMISTVKMFLKSKGTKELEVNCLNQVKSSLLKTSKSLRQNLGKKLDKEDKVRECQ 720
YACARNMISTVKMFLKSKGTKELEVNCLNQVKSSLLKTSKSLRQNLGKKLDKEDKVRECQ
Sbjct: 661 YACARNMISTVKMFLKSKGTKELEVNCLNQVKSSLLKTSKSLRQNLGKKLDKEDKVRECQ 720
Query: 721 LQVFLRLEMCLQCPSINESTDDMEQVVEEVTDLLRMVCLTEDSAYLAEFLEEILRLYIDS 780
LQVFLRLEMCLQCPSINESTDDMEQVVEEVTDLLRMVCLTEDSAYLAEFLEEILRLYIDS
Sbjct: 721 LQVFLRLEMCLQCPSINESTDDMEQVVEEVTDLLRMVCLTEDSAYLAEFLEEILRLYIDS 780
Query: 781 IPKTLGNLYNSLGFVIPQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPE 840
IPKTLGNLYNSLGFVIPQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPE
Sbjct: 781 IPKTLGNLYNSLGFVIPQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPE 840
Query: 841 SDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPAPQQPSQ 900
SDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPAPQQPSQ
Sbjct: 841 SDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPAPQQPSQ 900
Query: 901 PVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNKGYHK 960
PVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNKGYHK
Sbjct: 901 PVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNKGYHK 960
Query: 961 LLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLS 1020
LLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLS
Sbjct: 961 LLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLS 1020
Query: 1021 FSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPS 1080
FSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPS
Sbjct: 1021 FSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPS 1080
Query: 1081 EKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQK 1140
EKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQK
Sbjct: 1081 EKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQK 1140
Query: 1141 SPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQG 1200
SPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQG
Sbjct: 1141 SPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQG 1200
Query: 1201 TQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
TQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT
Sbjct: 1201 TQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
Query: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS 1320
PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS
Sbjct: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS 1320
Query: 1321 KKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSK 1380
KKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSK
Sbjct: 1321 KKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSK 1380
Query: 1381 VGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGY 1440
VGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGY
Sbjct: 1381 VGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGY 1440
Query: 1441 PGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSS 1500
PGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSS
Sbjct: 1441 PGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSS 1500
Query: 1501 LSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYE 1560
LSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYE
Sbjct: 1501 LSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYE 1560
Query: 1561 VELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPT 1620
VELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPT
Sbjct: 1561 VELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPT 1620
Query: 1621 YVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPD 1680
YVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPD
Sbjct: 1621 YVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPD 1680
Query: 1681 IIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLESEGKDHGLELSIHRTPILEDFEL 1740
IIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLESEGKDHGLELSIHRTPILEDFEL
Sbjct: 1681 IIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLESEGKDHGLELSIHRTPILEDFEL 1740
Query: 1741 EGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLREDSEVS 1800
EGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLREDSEVS
Sbjct: 1741 EGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLREDSEVS 1800
Query: 1801 KSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPLLFQGKTPS 1860
KSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPLLFQGKTPS
Sbjct: 1801 KSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPLLFQGKTPS 1860
Query: 1861 SQSKDPRDEDVDVLPSTVEDSPFSRAFSRRRPISRTYTRKKLMGTWLEDL 1910
SQSKDPRDEDVDVLPSTVEDSPFSRAFSRRRPISRTYTRKKLMGTWLEDL
Sbjct: 1861 SQSKDPRDEDVDVLPSTVEDSPFSRAFSRRRPISRTYTRKKLMGTWLEDL 1910
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 89.7 bits (221), Expect = 2e-17
Identities = 131/614 (21%), Positives = 209/614 (34%), Gaps = 55/614 (8%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSL--SFSKTTPRRISHTPQTPLYTP 1135
+P E K+ + T P + P + KS + + P P TP
Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 419
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT 1195
K PA TP + A ++P +P K P T+ T+ + P T
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTT 478
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAA 1255
PK P L T ++PE P+ P + P T +P T P+AA
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538
Query: 1256 AFMGTPQNQTHQQPHVLRAARAEEPAQKL-KDKAIKTPKRPGNSTVTSSPPVTPKKLFTS 1314
A TP+ P +EPA K+ A TPK +T+ P TPKK
Sbjct: 539 A-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 597
Query: 1315 PLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASL-SCPVPSTPPELSQRATLDTV 1373
L + K P + + P+P P A + P P+TP + +
Sbjct: 598 ELAPTTTKEP-TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 656
Query: 1374 PPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQS 1433
P P K T+ + A TP +P P + +K +P++
Sbjct: 657 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPET 715
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRT 1493
PP S+P T+ E T+ H D + LS E T
Sbjct: 716 PPPTTS----------EVSTP---TTTKEPTTI------HKSPDESTPELSAEP-----T 751
Query: 1494 ADAEKSSLSHPGIP--PSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHST 1551
A ++S PG+P +P + P TT + L P +T
Sbjct: 752 PKALENSPKEPGVPTTKTPAATKP----------EMTTTAKDKTTERDLRTTP----ETT 797
Query: 1552 DSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPR-- 1609
+A T E + + K+ +S+ + + ++L + P ++ +
Sbjct: 798 TAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 857
Query: 1610 --ASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
+ ++KPE T S +T K + T + T T P + P +
Sbjct: 858 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP---RVRKPKT 914
Query: 1668 TPSPKHSGKTTPDI 1681
TP+P+ T P++
Sbjct: 915 TPTPRKMTSTMPEL 928
Score = 84.0 bits (206), Expect = 1e-15
Identities = 129/592 (21%), Positives = 198/592 (33%), Gaps = 87/592 (14%)
Query: 1109 SHQKSLSFSKTTPRRISHTPQT---PLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
S +++ S KT+ + ++ T + P E K PA TP + S++P
Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 231
Query: 1166 DSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSC 1225
+P K P A T TP+ P T+ P +P +P
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------------APTTPKE 277
Query: 1226 PAPPTSSTAQPR--RECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQK 1283
PAP T+ P + T ++P T P+ A TP+ P +EPA
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
K+ A TPK P + P TPK+ + K P + E PSP + P
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKE-----PAPTTPKEPAPTTTKE-PSPTTPKEPAP 390
Query: 1344 QMSPSVAASLSCP-------VPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIV 1396
+ S + P P+TP E S T + P P +K +
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA------- 443
Query: 1397 ECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLL 1456
P P T PA T + +P +P E P P + ++P
Sbjct: 444 ---PTTPKEPAPTTPKEPAPTTTKKP-------APTTPKE----PAPTTPKETAPTTPKK 489
Query: 1457 ITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPG 1516
+T T + E K + EE + ++ P P +P + P
Sbjct: 490 LTPTTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPN 541
Query: 1517 SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIK 1576
+P P+ T ++ + + P + + + T L+ A PK
Sbjct: 542 TPKEPA-----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK---- 592
Query: 1577 KIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCP--------- 1627
P+ A +KE +S + P A + +P PT P P
Sbjct: 593 --KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650
Query: 1628 RLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTP 1679
L P + A T T GP+ST T P +PK + TTP
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTST-----TSDKPAPTTPKETAPTTP 697
Score = 60.8 bits (146), Expect = 1e-08
Identities = 93/378 (24%), Positives = 142/378 (37%), Gaps = 44/378 (11%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHT-----PQTPL 1132
+P E K + TL P TPKK K L+ TT S T P TP
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELA-PTTTKEPTSTTCDKPAPTTPK 621
Query: 1133 YTPERLQKSPAKMTP------TKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGT 1186
T K PA TP T + +LK+ + P ++ P T+ T
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTST 679
Query: 1187 SLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR--RECLTPI 1244
+ + P TPK P P T P +P +P P P TS + P +E T
Sbjct: 680 TSDKPAPTTPKETAPTTPKE-PAPTTPKK--PAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 1245 RDPLRTPPRAAAFMGTPQ--NQTHQQPHV----LRAARAEEPAQKLKDKAIKTPKRPGNS 1298
+ P + P +A TP+ + ++P V AA E KDK + R
Sbjct: 737 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795
Query: 1299 TVTSSPPVTPKKLFTSPLCDVSK----KSPFRKSKIECPSPGELDQ-KEPQMSPSVAAS- 1352
T T++P +T + T+ SK + + + +P ++ K ++P V +
Sbjct: 796 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTK 855
Query: 1353 ---LSCPVPSTPPELSQ---RAT---LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDAS 1403
+ + + P E ++ RAT T P P+K K+ T P+ +P +
Sbjct: 856 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 915
Query: 1404 ATPGVGTADSPAAPTDSR 1421
TP T+ P SR
Sbjct: 916 PTPRKMTSTMPELNPTSR 933
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 89.7 bits (221), Expect = 2e-17
Identities = 131/614 (21%), Positives = 209/614 (34%), Gaps = 55/614 (8%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSL--SFSKTTPRRISHTPQTPLYTP 1135
+P E K+ + T P + P + KS + + P P TP
Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 460
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT 1195
K PA TP + A ++P +P K P T+ T+ + P T
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTT 519
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAA 1255
PK P L T ++PE P+ P + P T +P T P+AA
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579
Query: 1256 AFMGTPQNQTHQQPHVLRAARAEEPAQKL-KDKAIKTPKRPGNSTVTSSPPVTPKKLFTS 1314
A TP+ P +EPA K+ A TPK +T+ P TPKK
Sbjct: 580 A-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 638
Query: 1315 PLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASL-SCPVPSTPPELSQRATLDTV 1373
L + K P + + P+P P A + P P+TP + +
Sbjct: 639 ELAPTTTKEP-TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 697
Query: 1374 PPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQS 1433
P P K T+ + A TP +P P + +K +P++
Sbjct: 698 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPET 756
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRT 1493
PP S+P T+ E T+ H D + LS E T
Sbjct: 757 PPPTTS----------EVSTP---TTTKEPTTI------HKSPDESTPELSAEP-----T 792
Query: 1494 ADAEKSSLSHPGIP--PSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHST 1551
A ++S PG+P +P + P TT + L P +T
Sbjct: 793 PKALENSPKEPGVPTTKTPAATKP----------EMTTTAKDKTTERDLRTTP----ETT 838
Query: 1552 DSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPR-- 1609
+A T E + + K+ +S+ + + ++L + P ++ +
Sbjct: 839 TAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 898
Query: 1610 --ASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
+ ++KPE T S +T K + T + T T P + P +
Sbjct: 899 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP---RVRKPKT 955
Query: 1668 TPSPKHSGKTTPDI 1681
TP+P+ T P++
Sbjct: 956 TPTPRKMTSTMPEL 969
Score = 84.0 bits (206), Expect = 1e-15
Identities = 129/592 (21%), Positives = 198/592 (33%), Gaps = 87/592 (14%)
Query: 1109 SHQKSLSFSKTTPRRISHTPQT---PLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
S +++ S KT+ + ++ T + P E K PA TP + S++P
Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 272
Query: 1166 DSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSC 1225
+P K P A T TP+ P T+ P +P +P
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------------APTTPKE 318
Query: 1226 PAPPTSSTAQPR--RECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQK 1283
PAP T+ P + T ++P T P+ A TP+ P +EPA
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
K+ A TPK P + P TPK+ + K P + E PSP + P
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKE-----PAPTTPKEPAPTTTKE-PSPTTPKEPAP 431
Query: 1344 QMSPSVAASLSCP-------VPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIV 1396
+ S + P P+TP E S T + P P +K +
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA------- 484
Query: 1397 ECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLL 1456
P P T PA T + +P +P E P P + ++P
Sbjct: 485 ---PTTPKEPAPTTPKEPAPTTTKKP-------APTTPKE----PAPTTPKETAPTTPKK 530
Query: 1457 ITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPG 1516
+T T + E K + EE + ++ P P +P + P
Sbjct: 531 LTPTTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPN 582
Query: 1517 SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIK 1576
+P P+ T ++ + + P + + + T L+ A PK
Sbjct: 583 TPKEPA-----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK---- 633
Query: 1577 KIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCP--------- 1627
P+ A +KE +S + P A + +P PT P P
Sbjct: 634 --KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691
Query: 1628 RLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTP 1679
L P + A T T GP+ST T P +PK + TTP
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTST-----TSDKPAPTTPKETAPTTP 738
Score = 60.8 bits (146), Expect = 1e-08
Identities = 93/378 (24%), Positives = 142/378 (37%), Gaps = 44/378 (11%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHT-----PQTPL 1132
+P E K + TL P TPKK K L+ TT S T P TP
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELA-PTTTKEPTSTTCDKPAPTTPK 662
Query: 1133 YTPERLQKSPAKMTP------TKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGT 1186
T K PA TP T + +LK+ + P ++ P T+ T
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTST 720
Query: 1187 SLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR--RECLTPI 1244
+ + P TPK P P T P +P +P P P TS + P +E T
Sbjct: 721 TSDKPAPTTPKETAPTTPKE-PAPTTPKK--PAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 1245 RDPLRTPPRAAAFMGTPQ--NQTHQQPHV----LRAARAEEPAQKLKDKAIKTPKRPGNS 1298
+ P + P +A TP+ + ++P V AA E KDK + R
Sbjct: 778 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836
Query: 1299 TVTSSPPVTPKKLFTSPLCDVSK----KSPFRKSKIECPSPGELDQ-KEPQMSPSVAAS- 1352
T T++P +T + T+ SK + + + +P ++ K ++P V +
Sbjct: 837 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTK 896
Query: 1353 ---LSCPVPSTPPELSQ---RAT---LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDAS 1403
+ + + P E ++ RAT T P P+K K+ T P+ +P +
Sbjct: 897 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 956
Query: 1404 ATPGVGTADSPAAPTDSR 1421
TP T+ P SR
Sbjct: 957 PTPRKMTSTMPELNPTSR 974
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 89.7 bits (221), Expect = 2e-17
Identities = 131/614 (21%), Positives = 209/614 (34%), Gaps = 55/614 (8%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSL--SFSKTTPRRISHTPQTPLYTP 1135
+P E K+ + T P + P + KS + + P P TP
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 512
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT 1195
K PA TP + A ++P +P K P T+ T+ + P T
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTT 571
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAA 1255
PK P L T ++PE P+ P + P T +P T P+AA
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631
Query: 1256 AFMGTPQNQTHQQPHVLRAARAEEPAQKL-KDKAIKTPKRPGNSTVTSSPPVTPKKLFTS 1314
A TP+ P +EPA K+ A TPK +T+ P TPKK
Sbjct: 632 A-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690
Query: 1315 PLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASL-SCPVPSTPPELSQRATLDTV 1373
L + K P + + P+P P A + P P+TP + +
Sbjct: 691 ELAPTTTKEP-TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749
Query: 1374 PPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQS 1433
P P K T+ + A TP +P P + +K +P++
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPET 808
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRT 1493
PP S+P T+ E T+ H D + LS E T
Sbjct: 809 PPPTTS----------EVSTP---TTTKEPTTI------HKSPDESTPELSAEP-----T 844
Query: 1494 ADAEKSSLSHPGIP--PSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHST 1551
A ++S PG+P +P + P TT + L P +T
Sbjct: 845 PKALENSPKEPGVPTTKTPAATKP----------EMTTTAKDKTTERDLRTTP----ETT 890
Query: 1552 DSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPR-- 1609
+A T E + + K+ +S+ + + ++L + P ++ +
Sbjct: 891 TAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 950
Query: 1610 --ASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
+ ++KPE T S +T K + T + T T P + P +
Sbjct: 951 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP---RVRKPKT 1007
Query: 1668 TPSPKHSGKTTPDI 1681
TP+P+ T P++
Sbjct: 1008 TPTPRKMTSTMPEL 1021
Score = 85.1 bits (209), Expect = 6e-16
Identities = 174/832 (20%), Positives = 278/832 (33%), Gaps = 144/832 (17%)
Query: 879 PKVSKRATKKENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKR-----GL 933
P SK+A P P SQ +K T + K P+K+ K+ +
Sbjct: 72 PPSSKKA-------PPPSGASQTIKSTTKRSPK-----------PPNKKKTKKVIESEEI 113
Query: 934 PRSHSVSAVDGLEDKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSD--P 991
HSVS + + K+ KS + ++++ K+L + K + P
Sbjct: 114 TEEHSVSENQESSSSSSSSSSSSTIRKI--KSSKNSAANRELQKKLKVKDNKKNRTKKKP 171
Query: 992 GPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVS-QPKSRSVQRVHSFQQDK 1050
P VV+E+ D + ++ T + VS PK + + ++
Sbjct: 172 TPKPPVVDEAGSGLDNGDFK-------VTTPDTSTTQHNKVSTSPKITTAKPINP----- 219
Query: 1051 SDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSH 1110
R + P S S ++ L + E + + + + Q+ +K+
Sbjct: 220 ---RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 276
Query: 1111 QKSLS-----FSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
K L+ +K TP+ + T L TP K P TP + A S++P
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKGPALTTP----KEPTPTTPKEPA--------STTPKE 324
Query: 1166 DSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSC 1225
+P K P A T TP+ P T+ P +P +P
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------------APTTPKE 370
Query: 1226 PAPPTSSTAQPR--RECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQK 1283
PAP T+ P + T ++P T P+ A TP+ P +EPA
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPT 429
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
K+ A TPK P + P TPK+ + K P + E PSP + P
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKE-----PAPTTPKEPAPTTTKE-PSPTTPKEPAP 483
Query: 1344 QMSPSVAASLSCP-------VPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIV 1396
+ S + P P+TP E S T + P P +K +
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA------- 536
Query: 1397 ECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLL 1456
P P T PA T + +P +P E P P + ++P
Sbjct: 537 ---PTTPKEPAPTTPKEPAPTTTKKP-------APTTPKE----PAPTTPKETAPTTPKK 582
Query: 1457 ITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPG 1516
+T T + E K + EE + ++ P P +P + P
Sbjct: 583 LTPTTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPN 634
Query: 1517 SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIK 1576
+P P+ T ++ + + P + + + T L+ A PK
Sbjct: 635 TPKEPA-----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK---- 685
Query: 1577 KIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCP--------- 1627
P+ A +KE +S + P A + +P PT P P
Sbjct: 686 --KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743
Query: 1628 RLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTP 1679
L P + A T T GP+ST T P +PK + TTP
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTST-----TSDKPAPTTPKETAPTTP 790
Score = 60.8 bits (146), Expect = 1e-08
Identities = 93/378 (24%), Positives = 142/378 (37%), Gaps = 44/378 (11%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHT-----PQTPL 1132
+P E K + TL P TPKK K L+ TT S T P TP
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELA-PTTTKEPTSTTCDKPAPTTPK 714
Query: 1133 YTPERLQKSPAKMTP------TKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGT 1186
T K PA TP T + +LK+ + P ++ P T+ T
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTST 772
Query: 1187 SLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR--RECLTPI 1244
+ + P TPK P P T P +P +P P P TS + P +E T
Sbjct: 773 TSDKPAPTTPKETAPTTPKE-PAPTTPKK--PAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 1245 RDPLRTPPRAAAFMGTPQ--NQTHQQPHV----LRAARAEEPAQKLKDKAIKTPKRPGNS 1298
+ P + P +A TP+ + ++P V AA E KDK + R
Sbjct: 830 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 888
Query: 1299 TVTSSPPVTPKKLFTSPLCDVSK----KSPFRKSKIECPSPGELDQ-KEPQMSPSVAAS- 1352
T T++P +T + T+ SK + + + +P ++ K ++P V +
Sbjct: 889 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTK 948
Query: 1353 ---LSCPVPSTPPELSQ---RAT---LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDAS 1403
+ + + P E ++ RAT T P P+K K+ T P+ +P +
Sbjct: 949 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1008
Query: 1404 ATPGVGTADSPAAPTDSR 1421
TP T+ P SR
Sbjct: 1009 PTPRKMTSTMPELNPTSR 1026
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 89.7 bits (221), Expect = 2e-17
Identities = 131/614 (21%), Positives = 209/614 (34%), Gaps = 55/614 (8%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSL--SFSKTTPRRISHTPQTPLYTP 1135
+P E K+ + T P + P + KS + + P P TP
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 553
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT 1195
K PA TP + A ++P +P K P T+ T+ + P T
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTT 612
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAA 1255
PK P L T ++PE P+ P + P T +P T P+AA
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672
Query: 1256 AFMGTPQNQTHQQPHVLRAARAEEPAQKL-KDKAIKTPKRPGNSTVTSSPPVTPKKLFTS 1314
A TP+ P +EPA K+ A TPK +T+ P TPKK
Sbjct: 673 A-PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731
Query: 1315 PLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASL-SCPVPSTPPELSQRATLDTV 1373
L + K P + + P+P P A + P P+TP + +
Sbjct: 732 ELAPTTTKEP-TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790
Query: 1374 PPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQS 1433
P P K T+ + A TP +P P + +K +P++
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPET 849
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRT 1493
PP S+P T+ E T+ H D + LS E T
Sbjct: 850 PPPTTS----------EVSTP---TTTKEPTTI------HKSPDESTPELSAEP-----T 885
Query: 1494 ADAEKSSLSHPGIP--PSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHST 1551
A ++S PG+P +P + P TT + L P +T
Sbjct: 886 PKALENSPKEPGVPTTKTPAATKP----------EMTTTAKDKTTERDLRTTP----ETT 931
Query: 1552 DSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPR-- 1609
+A T E + + K+ +S+ + + ++L + P ++ +
Sbjct: 932 TAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 991
Query: 1610 --ASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
+ ++KPE T S +T K + T + T T P + P +
Sbjct: 992 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP---RVRKPKT 1048
Query: 1668 TPSPKHSGKTTPDI 1681
TP+P+ T P++
Sbjct: 1049 TPTPRKMTSTMPEL 1062
Score = 85.1 bits (209), Expect = 6e-16
Identities = 174/832 (20%), Positives = 278/832 (33%), Gaps = 144/832 (17%)
Query: 879 PKVSKRATKKENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKR-----GL 933
P SK+A P P SQ +K T + K P+K+ K+ +
Sbjct: 113 PPSSKKA-------PPPSGASQTIKSTTKRSPK-----------PPNKKKTKKVIESEEI 154
Query: 934 PRSHSVSAVDGLEDKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSD--P 991
HSVS + + K+ KS + ++++ K+L + K + P
Sbjct: 155 TEEHSVSENQESSSSSSSSSSSSTIRKI--KSSKNSAANRELQKKLKVKDNKKNRTKKKP 212
Query: 992 GPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVS-QPKSRSVQRVHSFQQDK 1050
P VV+E+ D + ++ T + VS PK + + ++
Sbjct: 213 TPKPPVVDEAGSGLDNGDFK-------VTTPDTSTTQHNKVSTSPKITTAKPINP----- 260
Query: 1051 SDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSH 1110
R + P S S ++ L + E + + + + Q+ +K+
Sbjct: 261 ---RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 317
Query: 1111 QKSLS-----FSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
K L+ +K TP+ + T L TP K P TP + A S++P
Sbjct: 318 AKDLAPTSKVLAKPTPKAETTTKGPALTTP----KEPTPTTPKEPA--------STTPKE 365
Query: 1166 DSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSC 1225
+P K P A T TP+ P T+ P +P +P
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------------APTTPKE 411
Query: 1226 PAPPTSSTAQPR--RECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQK 1283
PAP T+ P + T ++P T P+ A TP+ P +EPA
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPT 470
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
K+ A TPK P + P TPK+ + K P + E PSP + P
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKE-----PAPTTPKEPAPTTTKE-PSPTTPKEPAP 524
Query: 1344 QMSPSVAASLSCP-------VPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIV 1396
+ S + P P+TP E S T + P P +K +
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA------- 577
Query: 1397 ECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLL 1456
P P T PA T + +P +P E P P + ++P
Sbjct: 578 ---PTTPKEPAPTTPKEPAPTTTKKP-------APTTPKE----PAPTTPKETAPTTPKK 623
Query: 1457 ITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPG 1516
+T T + E K + EE + ++ P P +P + P
Sbjct: 624 LTPTTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPN 675
Query: 1517 SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIK 1576
+P P+ T ++ + + P + + + T L+ A PK
Sbjct: 676 TPKEPA-----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK---- 726
Query: 1577 KIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCP--------- 1627
P+ A +KE +S + P A + +P PT P P
Sbjct: 727 --KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784
Query: 1628 RLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTP 1679
L P + A T T GP+ST T P +PK + TTP
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTST-----TSDKPAPTTPKETAPTTP 831
Score = 60.8 bits (146), Expect = 1e-08
Identities = 93/378 (24%), Positives = 142/378 (37%), Gaps = 44/378 (11%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHT-----PQTPL 1132
+P E K + TL P TPKK K L+ TT S T P TP
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELA-PTTTKEPTSTTCDKPAPTTPK 755
Query: 1133 YTPERLQKSPAKMTP------TKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGT 1186
T K PA TP T + +LK+ + P ++ P T+ T
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTST 813
Query: 1187 SLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR--RECLTPI 1244
+ + P TPK P P T P +P +P P P TS + P +E T
Sbjct: 814 TSDKPAPTTPKETAPTTPKE-PAPTTPKK--PAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 1245 RDPLRTPPRAAAFMGTPQ--NQTHQQPHV----LRAARAEEPAQKLKDKAIKTPKRPGNS 1298
+ P + P +A TP+ + ++P V AA E KDK + R
Sbjct: 871 KSPDESTPELSA-EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 929
Query: 1299 TVTSSPPVTPKKLFTSPLCDVSK----KSPFRKSKIECPSPGELDQ-KEPQMSPSVAAS- 1352
T T++P +T + T+ SK + + + +P ++ K ++P V +
Sbjct: 930 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTK 989
Query: 1353 ---LSCPVPSTPPELSQ---RAT---LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDAS 1403
+ + + P E ++ RAT T P P+K K+ T P+ +P +
Sbjct: 990 KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1049
Query: 1404 ATPGVGTADSPAAPTDSR 1421
TP T+ P SR
Sbjct: 1050 PTPRKMTSTMPELNPTSR 1067
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 76.6 bits (187), Expect = 2e-13
Identities = 159/692 (22%), Positives = 234/692 (33%), Gaps = 101/692 (14%)
Query: 1079 PSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERL 1138
PS KGS + S PAA K + K P TP L +P+
Sbjct: 1017 PSPKGSPAATPFPKGA--STPPAATPPSPKGSPAATPLPKGAPT----TPAATLPSPKGG 1070
Query: 1139 QKSPA-KMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKR--HTQAGEGTSLETKTPRT 1195
+P+ K PT AA S K P SP + + P + G T P T
Sbjct: 1071 PATPSLKGAPTPPAATPPSPK--GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 1196 PKRQGTQPPGFL---PNCTWPHSVNSSPESPS----------CPAPPTSSTAQPRRECLT 1242
P P G L P P + ++P SP P P ++ P+ T
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 1243 PI-----RDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGN 1297
P P TPP + TP + A P+ K + TP G
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPT-----TPAATPPSPK---GGLATPSPKGA 1240
Query: 1298 STVTSSPPVTPK--------------KLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
T ++ P +PK T P +P K P+P + P
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG---APNPAVVTPPSP 1297
Query: 1344 QMSPSVAASLSCPVP--STPPELSQRATLDTVPP---PPPSKVGKRCRKTSDPRRSIVEC 1398
+ P+ + P P +TPP S + + T PP P P V K + +
Sbjct: 1298 KGGPATSPPKGAPTPPAATPP--SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 1399 QPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLIT 1458
TP +P A T S + G +++P SP P P A PL
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSH--KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 1459 SDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIP-----PSPPSC 1513
A GDL ++ L+ A A + P P P+ P+
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVS---LKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 1514 GPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKL 1573
P SP P T +A A + A + +SP+ + P
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK--------EVPATPSS 1522
Query: 1574 RIKKIDPSSSLEAEPLSKEESSLGEESFL--PALSMPRASRSLSKPEPTYV--------- 1622
R I P+++L ++ K ++L + L PA+++P ++ + P P
Sbjct: 1523 RRDPIAPTATLLSK---KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579
Query: 1623 -SPPCPRLSHSTPGKSRGQTYICQACT-PTHGPSSTP---SPFQTDGVPWTPSPKH---S 1674
SPP S S + I A T P+ + TP +P + P TP+PK S
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS 1639
Query: 1675 GKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVG 1706
TP +KD P +V C G++ + G
Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671
Score = 68.9 bits (167), Expect = 4e-11
Identities = 138/582 (23%), Positives = 218/582 (37%), Gaps = 72/582 (12%)
Query: 1076 MISPSEK-GSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFS-KTTPRRISHTPQTPLY 1133
M PS K G A + T + +P + PKK+ ++ TP + TP P
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLS---PKKAPATPVTREGAATPSKGDLTP--PAV 1438
Query: 1134 TPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTP 1193
TP L+K+PA P A S D + P P K P + +S K P
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP-SPKEPPAPKQVAT---SSSPKKAP 1494
Query: 1194 RTPKRQGTQP-PGFLPNCTWPHSVNSSPESPSCPAPPTSS--------TAQPRRECLTP- 1243
TP G P +P+ P V ++P S P PT++ T P+ + P
Sbjct: 1495 ATPAPMGAPTLPAVIPSS--PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
Query: 1244 --IRDPLRTP--PRAAAFMGTPQNQTHQQPHVLRAAR---AEEPAQKLKDKAI------- 1289
+ P +TP P TP ++ P + + A P + L A+
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 1290 -------------KTPKRPGNSTVTSSPPVTPKKLFTSPL------CDVSKKSPFRKSKI 1330
K P P +SPPVTP L SP C + P + SK
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP-QASKG 1671
Query: 1331 ECPSPGELDQKEPQMSPSVAAS--LSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKT 1388
G KE ++P+ ++ ++ P P AT + P P +K G + +
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS 1731
Query: 1389 SDPRRSIVECQPDASATP-GVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRS 1447
+ ++ Q D+S T G + SP P + + L+ + + P P S
Sbjct: 1732 TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA--FEKVLPKPESAS 1789
Query: 1448 DWHASSP--LLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPG 1505
A SP L + + TL + + L S+ V E A A++ L P
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQF-----LPSSPGLVLESPSKPLAPADEDELL-PL 1843
Query: 1506 IPPSPPSCG-PGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELE 1564
IPP P S G P ++ + + SA+ + T+S S ++ ELE
Sbjct: 1844 IPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVP-ELE 1902
Query: 1565 MQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALS 1606
Q S + ++ ++ ++ EP+SK + S E+ A+S
Sbjct: 1903 EQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMS 1944
Score = 59.7 bits (143), Expect = 3e-08
Identities = 143/665 (21%), Positives = 212/665 (31%), Gaps = 108/665 (16%)
Query: 1079 PSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRI-SHTPQTPLYTPER 1137
P++KGSA N L S V + + S SK +P S TP +P P
Sbjct: 809 PTKKGSAGPDTPIGN-LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP-- 865
Query: 1138 LQKSPAKMTPTKQAAFKESLKDSSSPGHDS---PLDSKITPQKRHTQAGEGTSLETKTPR 1194
+P+ +TP K++ +P + P + TP + A TS
Sbjct: 866 ---TPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS------S 916
Query: 1195 TPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRA 1254
+PK+ P P + +SP P PP ++ P+ TP TPP A
Sbjct: 917 SPKKARATPA--------PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 1255 A-----------AFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVT-- 1301
+ G P P P A+ P G+ T
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 1302 ----SSPPVT--------------PKKLFTSPLCDV--SKKSPFRKSKIECPSPGELDQK 1341
S+PP PK T+P + K P S P+P
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 1342 EPQMSPSVAASLSCPVP--STPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQ 1399
P+ P+ + P+P +TPP S + L T PP P+ +
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPP--SPKGGLAT--PPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 1400 PDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITS 1459
P + T T SP + + + +PP +G G S A + T
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG--GLATPSPKGAPTTPAATP 1202
Query: 1460 DTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPL 1519
+ L + + G + + +G + K + + P P P GP +P
Sbjct: 1203 PSPKGGLATPSPK---GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP- 1258
Query: 1520 MPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKID 1579
G +A +L +P V G
Sbjct: 1259 --------PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG------PATS 1304
Query: 1580 PSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPR----LSHSTPG 1635
P P + S G P P+ + P P V+PP P+ L +TP
Sbjct: 1305 PPKGAPTPPAATPPSPKGS----PGTPPPKGA-----PTPPAVTPPSPKGTPTLPATTPS 1355
Query: 1636 KSRGQTYICQ-------ACTPTH--GPSSTPSPFQTDGVPWTPSPKHSGKTTPDIIKDWP 1686
G T A TP+H GP+ TP P G P PSPK T+P +I P
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTP-PSPKRG-PAIPSPK-GDPTSPAVIPLSP 1412
Query: 1687 RRKRA 1691
++ A
Sbjct: 1413 KKAPA 1417
Score = 48.5 bits (114), Expect = 6e-05
Identities = 109/496 (21%), Positives = 165/496 (33%), Gaps = 71/496 (14%)
Query: 1215 SVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRA 1274
S S+ SP P P ++ A+ PI P A+ M +P +
Sbjct: 572 SFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP-------ASSMTSPLGVNSSASVIKTD 624
Query: 1275 ARA-EEPAQKLKDKAIKTPKRPGNSTVTSSP----PVTPKKLFTSPLCDVSKKSPFRKSK 1329
+ A + A L ++ TP ++ P P T K T + SPF +
Sbjct: 625 SYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTY----TTTASPFLEGT 680
Query: 1330 IECPSPGELDQKEPQMS--PSV-AASLSCPVPSTP-------------PELSQRATLDTV 1373
+ +P KE ++ P V AS +CPV +P PE+ + ++
Sbjct: 681 VSL-APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL 739
Query: 1374 PP---PPPSKVGKRCRKTS---DPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGL 1427
PP PP +K TS S EC + S ++ G+
Sbjct: 740 PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
Query: 1428 SLSPQS--PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSV 1485
S+SPQ+ PP ++G GP DT L S L N LS
Sbjct: 800 SVSPQTKRPPTKKGSAGP----------------DTPIGNLSSPVSPVEASFLPENSLSF 843
Query: 1486 EEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPA 1545
+ + + + +H PPSP S + P T ++ + + NLP
Sbjct: 844 QGSK-------DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV-NLP- 894
Query: 1546 SAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPAL 1605
+ A+P + S PK + + + A P K + +
Sbjct: 895 --FPKEGPATPAPKQAPALSMTSSSPK-KARATPAPKGIPASPSPKGAPTPPAATPPSPK 951
Query: 1606 SMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSP--FQTD 1663
P P P +PP P+ +TP T G +TPSP T
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 1664 GVPWTPSPKHSGKTTP 1679
PSPK S TP
Sbjct: 1012 PAVTPPSPKGSPAATP 1027
Score = 32.7 bits (73), Expect = 3.5
Identities = 61/273 (22%), Positives = 87/273 (31%), Gaps = 47/273 (17%)
Query: 1141 SPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQG 1200
SPA AA + S S S +PL+ Q+ GT+L P
Sbjct: 50 SPAPQQCPLSAANQASPFPSPSTIASTPLEVPFP------QSSSGTAL-------PLGTA 96
Query: 1201 TQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
+ P FLPN P SP + + +P + T + P+ P
Sbjct: 97 PEAPTFLPNLIGPPI---SPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF 153
Query: 1261 PQNQTHQQPHVLRAARAE-----------EPA---QKLKDKAIKTPK-RPGNSTVTSSPP 1305
P N P V A EP K+ + + PK P + S+ P
Sbjct: 154 PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213
Query: 1306 ---VTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPP 1362
VTP S + + + +P I P + +SP SLS P +PP
Sbjct: 214 YHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273
Query: 1363 EL-------------SQRATLDTVPPPPPSKVG 1382
SQ+ PP P +G
Sbjct: 274 AALSLSTQSLPVVTSSQKTAGPNTPPDFPISLG 306
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 75.9 bits (185), Expect = 4e-13
Identities = 161/723 (22%), Positives = 254/723 (35%), Gaps = 104/723 (14%)
Query: 797 PQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQELRTRSAKKRR 856
P K LP S+ S + P SS+ S +P +E+ + K R
Sbjct: 405 PPKSPEKLPQSSSSESS--PPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR 462
Query: 857 KNALI-RHKSIAEV-SQNLRQIEIPKVSKRA-----TKKENSHPAPQQPSQPVKDTVQEV 909
+ R KS + S+ + + P +KR T + H + P + Q
Sbjct: 463 SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRW 522
Query: 910 TKVRRNLFNQELLSPSK---------------RSLKRGLPRSHSVS-AVDGLEDKLDNFK 953
+ R SP + RS +RG RSHS S A G +
Sbjct: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG--RSHSRSPATRGRSRSRTPAR 580
Query: 954 KNKGYHKLLTK--SVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEE---------SP 1002
+ + + + S + TP ++ R R+ + RS P SP
Sbjct: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP 640
Query: 1003 EKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQ-RENSPVQS 1061
+ S R+P + S SRT + S S+ +R R S + + R +P +
Sbjct: 641 ARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRG 700
Query: 1062 IRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTP 1121
+SL+ S +P +G + +N S+T+
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK----------------------SRTSQ 738
Query: 1122 RRISHTPQTPLYTPERL--QKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRH 1179
RR S + +P R+ ++S + +P +A + SL+ S S P TP +R
Sbjct: 739 RR-SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797
Query: 1180 TQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSS----PESPSCPAPPTSSTAQ 1235
+++TP R + PP + T +SS P+ S P S
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
Query: 1236 P----------RRECLTPIRDP---LRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQ 1282
P RR C DP RTP R + +P P +R+ P
Sbjct: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917
Query: 1283 KLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKE 1342
K+ KAI +P++ +S +SSP SP S+ +P R+S+ P +
Sbjct: 918 KV--KAIISPRQRSHSG-SSSP---------SPSRVTSRTTP-RRSRSVSPCSNVESRLL 964
Query: 1343 PQMSPSVAASLSCPV-PSTPPELSQRATLDTVP------PPPPSKVGKR--CRKTSDPRR 1393
P+ S S ++S V P TPP S ++ P PP PS G + C +
Sbjct: 965 PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDS 1024
Query: 1394 SIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASS 1453
+ C S GV ++ P + S SP R P +R H+ S
Sbjct: 1025 LVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS-HSES 1083
Query: 1454 PLL 1456
P L
Sbjct: 1084 PSL 1086
Score = 63.5 bits (153), Expect = 2e-09
Identities = 105/442 (23%), Positives = 165/442 (37%), Gaps = 56/442 (12%)
Query: 1045 SFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQ 1104
SF + + P P SL+ + S SP+ K + KK+ R SE + +
Sbjct: 150 SFDPQRRAREAKQPAPEPPKPYSLVRESSSSR-SPTPKQKKKKKKKDRGRR-SESSSPRR 207
Query: 1105 TPKKSHQKSLSFSKTTPRRISH---TPQTPLYTPERLQKSPAKMTPTKQA--AFKESLKD 1159
KKS +K S++ ++ H TP++ + ++ +K TP ++ A + + D
Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD 267
Query: 1160 SSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCT---WPHSV 1216
S+S S S+ K HT A G S +P + +R P P T P S
Sbjct: 268 SASSSDTSRSRSRSAAAKTHTTALAGRS---PSPASGRRGEGDAPFSEPGTTSTQRPSSP 324
Query: 1217 NSSPESPSCP----------APPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTH 1266
++ + PS P T + P R P P TP A G+PQ
Sbjct: 325 ETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP-EPPAPTPLLAERHGGSPQ---- 379
Query: 1267 QQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFR 1326
+ ++EP P + T SPP +P+KL S + S SP +
Sbjct: 380 ---PLATTPLSQEPV---------NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP-Q 426
Query: 1327 KSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCR 1386
+K+ + + +P +P +S P++ RA D PS+ R R
Sbjct: 427 PTKVSRHASSSPESPKPAPAPGSHREISSS-PTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
Query: 1387 KTSDPRRSIVECQP------DASATPGVGTADSPAAPTDSRDDQ-KGLSLSPQSP----- 1434
+ +R + S +P + S SR Q +G S SPQ P
Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
Query: 1435 --PERRGYPGPGLRSDWHASSP 1454
+RRG R H+ SP
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSP 567
Score = 62.0 bits (149), Expect = 5e-09
Identities = 226/1120 (20%), Positives = 384/1120 (34%), Gaps = 186/1120 (16%)
Query: 832 RRSVSGSPESDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENS 891
RRS S SP + R +S+KK+ +H+S +E + + PK +++ K+
Sbjct: 198 RRSESSSPRRE-----RKKSSKKK------KHRSESESKKRKHRSPTPKSKRKSKDKKRK 246
Query: 892 HPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDN 951
P+ + + + + S + RS R +A+ G +
Sbjct: 247 RSRSTTPAPKSRRAHRSTSA------DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300
Query: 952 FKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLR 1011
++ +G T R ++ P ++ +K ++ + R
Sbjct: 301 GRRGEGDAPFSEPGTTST-----------QRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 1012 RSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHS---FQQDKSDQRENSPVQSIRSPKS- 1067
SP ++ S A +++ S Q + + Q+ + E SP + PKS
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 1068 -LLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISH 1126
L + S SP ++ + + ++ +S PA P + +S S T+ R SH
Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA----PAPGSHREISSSPTSKNR-SH 464
Query: 1127 ----TPQTPLYTPER---LQKSPA--------KMTPTKQAAFKESLKDSSSPGHDSPLDS 1171
++ +TP R +SPA TPTK+ + S SP +
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR-----SRSPQWRRSRSA 519
Query: 1172 KITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTS 1231
+ + R Q G S + P + + TQ G + S + SP + T
Sbjct: 520 QRWGRSRSPQR-RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
Query: 1232 STAQPRRECLTPI--RDPLRTPPRAAAFMGTP------------QNQTHQQPHVLRAARA 1277
+ + R TP R RTP R + TP + ++ + V R +R+
Sbjct: 579 A-RRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS 637
Query: 1278 EEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSK---KSPFRKSKIECPS 1334
PA++ +TP R G S + +P + +P + ++P R+ + +
Sbjct: 638 RSPARRSGRSRSRTPARRGRSR-SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 1335 P-------------GELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKV 1381
P G + PQ +S S + +R+ ++ P S++
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ--RRSRSNSSPEMKKSRI 754
Query: 1382 -GKRCRKTSDPR---RSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPER 1437
+R R S PR +S + + S + S P SR ++PP
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR- 813
Query: 1438 RGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAE 1497
RS +S P S T S + H V+ G R
Sbjct: 814 --------RSRSSSSPPPKQKSKTPSRQSHSSSSPHP---------KVKSGTPPRQGSIT 856
Query: 1498 KSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQ 1557
+ + P SC S P ++ T R HS +SP
Sbjct: 857 SPQANEQSVTPQRRSCFESS---PDPELKSRTPSR----------------HSCSGSSPP 897
Query: 1558 TYEVEL----EMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRS 1613
+ S P+ ++K I + S SS S + + + PR SRS
Sbjct: 898 RVKSSTPPRQSPSRSSSPQPKVKAI-----ISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 1614 LSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKH 1673
+S P S PR SHS G S T + P S + SP+ P P
Sbjct: 953 VS-PCSNVESRLLPRYSHS--GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSL 1009
Query: 1674 SGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLESEGKDHGLELSIHRTP 1733
SG +P P+ K + + PGSLSL G++ S TP
Sbjct: 1010 SGSKSP-----CPQEK-----------SKDSLVQSCPGSLSLCA------GVKSS---TP 1044
Query: 1734 ILEDF------ELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGA 1787
E + +L+G Q S P+ ++ S L S+ + K R +
Sbjct: 1045 PGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP-SLQSKSQT-SPKGGRSRSS 1102
Query: 1788 KRICDLREDSEVSKSK---EGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASAL 1844
+ +L S + + + SP + P ++ F S S+ P+ S L S L
Sbjct: 1103 SPVTELASRSPIRQDRGEFSASPMLKSGMSP---EQSRFQSDSSSYPTVDSNSLLGQSRL 1159
Query: 1845 QALTQSPLLFQGKTPSSQSKDPRDEDVDVLPSTVEDSPFS 1884
+ + + + PR +D P V+D P S
Sbjct: 1160 ETAESKEKMALPPQEDATASPPRQKD-KFSPFPVQDRPES 1198
Score = 60.1 bits (144), Expect = 2e-08
Identities = 203/964 (21%), Positives = 341/964 (35%), Gaps = 172/964 (17%)
Query: 829 SSARRSVSGSPESDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKK 888
+++RR S SP+ LQ R+RS +++ + R +S + S + R+ + + R T++
Sbjct: 1755 TTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR-QRSRSRSRVTRR 1813
Query: 889 -------ENSHPAPQQPSQPVKDTVQEVTKV----RRNLFNQELLSPSKRSLKRGLPRSH 937
+ PA Q+ S+ + ++ R+ ++ +P KRS R P +H
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATH 1873
Query: 938 SVSAVDGLEDKLDNFKKNKGYHKLLT--KSVAETPVHKQISKRLLHRQIKGRSSDPGPDI 995
S L + ++++ ++ +S + T V ++ S+ + RS P +
Sbjct: 1874 RRSR---SRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPV 1930
Query: 996 ----------GVVEESPEKGDEISLRRS-----PRIKQLSFSRTHSAS---FYSVSQP-- 1035
S + ++ RRS P ++ S SRT + S + P
Sbjct: 1931 TRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVT 1990
Query: 1036 KSRSVQRVHSFQQDKSDQRENSPVQSIRS----PKSLLFGAMSEM-ISPSEKGSAR---- 1086
+ RS R + +S R SPV RS P ++ + S + P ++ +R
Sbjct: 1991 RRRSRSRTSPVTRRRSRSR-TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLA 2049
Query: 1087 MKKRSRN----------TLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISH----TPQTPL 1132
+++RSR+ +L PA + S S T P +H TP L
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109
Query: 1133 YTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKT 1192
+ S M+PT L SPG PL S TP QAG G+ ++
Sbjct: 2110 NSSRMSCFSRPSMSPT-------PLDRCRSPGMLEPLGSSRTPMSVLQQAG-GSMMDGPG 2161
Query: 1193 PRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPL---- 1248
PR P Q T P ++ + + P P S+ R P PL
Sbjct: 2162 PRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLR 2221
Query: 1249 ---------RTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNST 1299
R P +AA M +T P + A + PA S
Sbjct: 2222 TAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSA 2281
Query: 1300 VTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPS 1359
V + P TP T+P +++ +P+ A+LS
Sbjct: 2282 VNLADPRTP----TAPAVNLA----------------------GARTPAALAALSLTGSG 2315
Query: 1360 TPPELSQRATLDTVPPPPPSK--VGKRCRKTSDP-----RRSIVECQP----DASATPGV 1408
TPP + + P P S VG R + P R+ P A P +
Sbjct: 2316 TPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL 2375
Query: 1409 GTAD--SPAAPTDSRDDQKGLSLSP-------QSPPERRGY--------PGPGLRSDWHA 1451
A+ SP P + + G + P ++PP P P R
Sbjct: 2376 SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP 2435
Query: 1452 SSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRT---ADAEKSSLSH----- 1503
S LL + + + + A L + V + L + A S+ H
Sbjct: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495
Query: 1504 ---PGIPPS-----PPSCGPGSP-----LMPSRDVHCTTDGRQCQASAQLDNLPASAWHS 1550
PG+P S P S G P L P+++ ++ +S+ + +S+ S
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
Query: 1551 TDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRA 1610
+ S+S + L +Q P++ +K++ PS + P KE G P P
Sbjct: 2556 SGSSSSDSEGSSLPVQ----PEVALKRV-PSPT----PAPKEAVREGR----PPEPTPAK 2602
Query: 1611 SRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQ--TDGVPWT 1668
+ S + S S S+ S + + + + SS+PSP + +P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 1669 PSPK 1672
SPK
Sbjct: 2663 ASPK 2666
Score = 56.2 bits (134), Expect = 3e-07
Identities = 229/1094 (20%), Positives = 384/1094 (35%), Gaps = 149/1094 (13%)
Query: 894 APQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFK 953
+P + S P ++ +R+ SPS+ + + RS SVS +E +L
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRY 967
Query: 954 KNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDI-GVVEESPEKGDEISLRR 1012
+ G TK ETP + S + + PGP + G P++ + SL +
Sbjct: 968 SHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQ 1027
Query: 1013 S-----PRIKQLSFSRTHSASFYSVS------QPKSRSVQRVHSFQQDKSDQRENSPV-- 1059
S + S S++ VS Q ++ R + + SP
Sbjct: 1028 SCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ 1087
Query: 1060 -QSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPA--AYQTPKKSHQKSLSF 1116
+S SPK G S SP + ++R R S P + +P++S +S S
Sbjct: 1088 SKSQTSPK----GGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSS 1143
Query: 1117 SKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAF---KESLKDSSSPGHDSPLDSKI 1173
S T S Q+ L T E +K + P + A ++ K S P D P S +
Sbjct: 1144 SYPTVDSNSLLGQSRLETAESKEKMA--LPPQEDATASPPRQKDKFSPFPVQDRPESSLV 1201
Query: 1174 TPQKRHT----QAGEGTSLETKTPRTPKRQGTQ-------------PPG----FLPNCTW 1212
T ++G G+S ETK + +Q P G L +
Sbjct: 1202 FKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELK 1261
Query: 1213 PHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQ--PH 1270
S ++ SP P S + + + + + P A+++ G + H++
Sbjct: 1262 EMSTSNFESSPEVEERPAVSLTLDQSQSQASL-EAVEVPSMASSWGGPHFSPEHKELSNS 1320
Query: 1271 VLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTP--KKLFTSPLCDVSKKSPFRKS 1328
LR P + + T G S+ P +L T P D+ ++S
Sbjct: 1321 PLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG 1380
Query: 1329 KIECP-SPGELDQKEPQMSPSVAASLSCPVPSTPP-ELSQRATLDTVPPPPPSKVGKRCR 1386
SP +++ + S+++ + VP TP E S A+ + P +R R
Sbjct: 1381 HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR 1440
Query: 1387 KTSDPRRSIVECQPDASATPGV--GTADSPAAPT------DSRDDQKGLSLSPQSP-PER 1437
S P P + G G D P P+ DS + K L PQ+P P
Sbjct: 1441 SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKAL---PQTPRPRS 1497
Query: 1438 RGYPGPGLRSDW------HASSPLLITSDTEHVTLLSEAEHHGIG---DLKSNVLSVEEG 1488
R P L + + S + T T L + G D+K + E
Sbjct: 1498 RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS 1557
Query: 1489 EGLRTADAE---KSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPA 1545
E + D++ ++ L S P S L P R + +S ++ + P
Sbjct: 1558 ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS--------RSGSSPEVKDKPR 1609
Query: 1546 SAWH-------STDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGE 1598
+A S + +P + ++ K R + SSS E+ P +S
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR 1669
Query: 1599 ESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGP---SS 1655
R SRS +P+ +PP R S S+P +R ++ + + P S
Sbjct: 1670 ----------RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
Query: 1656 TPSPFQTDGVPWTPSPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSL 1715
TP + +P P +++ RR+ A ++S RG + P L
Sbjct: 1720 TPPRHRRSPSVSSPEPAEKSRSS-------RRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772
Query: 1716 LESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKR 1775
S + + R D+S S + + S SR R
Sbjct: 1773 SRSRSRREKTRTTRRR----------------DRSGSSQSTSRRRQRS-------RSRSR 1809
Query: 1776 VLLAKEEADRGAKRICDLREDSEVSKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAV 1835
V + R +E S S + S + P T + S ++P P
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS----RTPPTSRKR-SRSRTSPAPWKRS 1864
Query: 1836 RSCLS-ASALQALTQSPLLFQGK-----TPSSQSKDPRDEDVDVLPSTVEDSPFSRAFSR 1889
RS S A+ ++ +++PL+ + + +P S+ + V S SP SR SR
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924
Query: 1890 RR--PISRTYTRKK 1901
R P++R +R +
Sbjct: 1925 SRTPPVTRRRSRSR 1938
Score = 38.9 bits (89), Expect = 0.049
Identities = 85/417 (20%), Positives = 151/417 (36%), Gaps = 51/417 (12%)
Query: 1061 SIRSPKSLLFGAMSEMISP-SEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKT 1119
S R+P++ A + ++ P S +A + T + PA+ + + + S + T
Sbjct: 2326 SSRTPQA---PASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALS-GANLT 2381
Query: 1120 TPR-------RISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSK 1172
+PR R+S PL R + P+ P++ E SS +P S
Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPS--APSQSRMTSERAPSPSSRMGQAPSQSL 2439
Query: 1173 ITPQKRHTQAGEGTSLETKT----PRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAP 1228
+ P + ++ ++ ++ +T G+Q T S S PAP
Sbjct: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP 2499
Query: 1229 --PTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKD 1286
P S +P P + P AA + ++ ++ + +
Sbjct: 2500 GVPHSDVGEP------PASTGAQQPSALAALQPAKERRSSSSSS---SSSSSSSSSSSSS 2550
Query: 1287 KAIKTPKRPGNSTVTSSPPVTPK-KLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQM 1345
+ + + + SS PV P+ L P + K R+ + P+P + ++
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
Query: 1346 SPSVAASLSCPVPSTPPELSQRATLDTVPP--------PPPSKVGKRCR-KTSDPRRSIV 1396
S S ++S S S+ S ++ + P P+K G + K + P++
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP-- 2668
Query: 1397 ECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASS 1453
PG + SP P DS D + LS SP RR P P R +SS
Sbjct: 2669 --------PPGERRSRSPRKPIDSLRDSRSLSYSPVE--RRRPSPQPSPRDQQSSSS 2715
Score = 33.9 bits (76), Expect = 1.6
Identities = 47/192 (24%), Positives = 69/192 (35%), Gaps = 26/192 (13%)
Query: 988 SSDPGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQ 1047
S P P V E P + +R R S S + S+S S S S S S
Sbjct: 2581 SPTPAPKEAVREGRPP--EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638
Query: 1048 QDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPK 1107
S +SP + P++L A + P E+ S +K + DS
Sbjct: 2639 SSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS---------- 2688
Query: 1108 KSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDS 1167
+SLS+S RR S P +P Q S +++ + + DS SP H
Sbjct: 2689 ----RSLSYSPVERRRPSPQP-----SPRDQQSS-----SSERGSRRGQRGDSRSPSHKR 2734
Query: 1168 PLDSKITPQKRH 1179
++ RH
Sbjct: 2735 RRETPSPRPMRH 2746
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 72.0 bits (175), Expect = 5e-12
Identities = 131/662 (19%), Positives = 251/662 (37%), Gaps = 90/662 (13%)
Query: 843 ELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPAPQ-QPSQP 901
EL+ L++ R+ + + + A+++ I+ R TK E + + Q
Sbjct: 331 ELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLN 390
Query: 902 VKDTVQ-EVTKVRRNLFNQEL---LSPSKRSLKRGLPRSHSVSAVDGL--EDKLDNFKKN 955
VK + E+ R+ L +E P SL GLP+ SVS + E+K+ +K+
Sbjct: 391 VKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKS 450
Query: 956 KGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPR 1015
+ ++ + ET V +++++ + + + + + G EE E G+E + +SP
Sbjct: 451 EKETVIVEEQTEETQVTEEVTEE---EEKEAKEEEGKEEEGGEEEEAEGGEEET--KSPP 505
Query: 1016 IKQLSFSRTHSAS-----FYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQS--------- 1061
++ + + S S ++ KS + S + KS ++ SP +
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 1062 ------------IRSPKSLLFGAMSEMISPSEKGSAR-------------------MKKR 1090
++SP+ A E SP+E S +K+
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Query: 1091 SRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAK-MTPTK 1149
+++ + + P ++P K KS +K+ + + +P+ + KSP K +P K
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685
Query: 1150 -QAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSL----ETKTPRTPKRQGTQPP 1204
+A E K SP +K +P K ++ E E KTP K +
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAK-SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 1205 GFLPNCTWPHSVNS-SPESPSCPAPPTSSTAQPR----RECLTPIRDPLRTPPRAAAFM- 1258
P + +SP P P + +P+++ +++P +A + +
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Query: 1259 ---GTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSP 1315
P+ + ++ V + EE Q++K K P P TPK T
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVK------VKEPPKKAEEEKAPATPK---TEE 855
Query: 1316 LCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPP 1375
D K+ +K E P P ++KE P+V V + E + + T
Sbjct: 856 KKDSKKEEAPKK---EAPKPKVEEKKE----PAVEKPKESKVEAKKEEAEDKKKVPTPEK 908
Query: 1376 PPPSKVGKRCRKTSDPRRSIVECQP-DASATPGVGTADSPAAPTDSRDDQKGLSLSPQSP 1434
P+KV + + + + +P DA A A+ A + +D ++ + P+
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Query: 1435 PE 1436
P+
Sbjct: 969 PK 970
Score = 54.7 bits (130), Expect = 9e-07
Identities = 76/399 (19%), Positives = 162/399 (40%), Gaps = 37/399 (9%)
Query: 1047 QQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEV--PAAYQ 1104
++++ + +E + + G E SP + +A +K +++ + E PA +
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 1105 TPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFK--ESLKDSSS 1162
+P+K KS + K+ + S + PE KSP K A K E K +
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE--AKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 1163 PGHDSPLDSKITPQKRHTQAGEGTSLETKTP---RTPKRQGTQPPGFLPNCTWPHSVNSS 1219
SP ++K +P+K + E E K+P ++P ++ + P +
Sbjct: 590 EEAKSPAEAK-SPEKAKSPVKE----EAKSPAEAKSPVKEEAKSP-------------AE 631
Query: 1220 PESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRA-ARAE 1278
+SP PT A+ + +P ++ ++P +A + + + ++A A++
Sbjct: 632 VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP 691
Query: 1279 EPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGEL 1338
E A+ + K+P++ + +P+K SP+ + +K KS ++ +
Sbjct: 692 EKAKSPVKEEAKSPEKA--KSPVKEEAKSPEKA-KSPVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 1339 DQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVEC 1398
K P+ + ++ + P TP + R+ D P S V + + P ++
Sbjct: 749 KAKSPEKAKTL--DVKSPEAKTPAKEEARSPADKFPEKAKSPVKE---EVKSPEKAKSPL 803
Query: 1399 QPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPER 1437
+ DA A P + ++++K + + PP++
Sbjct: 804 KEDAKA-PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841
Score = 53.9 bits (128), Expect = 1e-06
Identities = 101/536 (18%), Positives = 191/536 (35%), Gaps = 38/536 (7%)
Query: 887 KKENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLE 946
++E P ++ + P K+ V + ++ E SP K K A +
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKS--PAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555
Query: 947 DKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIG---VVEESPE 1003
++ + + K K KS AE ++ +K + K + P+ V EE+
Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSPEK-AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 1004 KGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQS-I 1062
+ S + A + + KS + ++ KS ++ SPV++
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 1063 RSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPR 1122
+SP+ +E SP EK + +K+ +++ P ++P K KS +K+ +
Sbjct: 675 KSPEKAKSPVKAEAKSP-EKAKSPVKEEAKS------PEKAKSPVKEEAKSPEKAKSPVK 727
Query: 1123 RISHTPQTPLYTPERLQKSPAKM-TPTKQAAFKESLKDSSSPGHD---SPLDSKITPQKR 1178
+ TP+ + KSP K +P K ++ +P + SP D P+K
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK--FPEKA 785
Query: 1179 HTQAGEGTSLETKTPRTPKRQGTQPPGFLPN---CTWPHSVNSSPESPSCPAPPTSSTAQ 1235
+ E K K P +P P P+ PP A+
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK--AE 843
Query: 1236 PRRECLTPIRDPLRTPPRAAA---FMGTPQNQTHQQPHVLRAARAEEPAQKLK---DKAI 1289
+ TP + + + A P+ + ++P V + ++ A+K + K +
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903
Query: 1290 KTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSV 1349
TP++ + V PK+ +V+KK P E P E + P+ +
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEK-----TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK 958
Query: 1350 AASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASAT 1405
P E + T+ P ++ K+S + + +P AT
Sbjct: 959 EEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK--DSKPPEKAT 1012
Score = 35.8 bits (81), Expect = 0.41
Identities = 73/410 (17%), Positives = 149/410 (36%), Gaps = 44/410 (10%)
Query: 797 PQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQ-ELRTRSAKKR 855
P K P + S + K S S + + SPE + + +S +K
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 856 RKNALIRHKSIAEVSQNLRQ-IEIPKVSKRATKKENSHP------------APQQPSQPV 902
+ KS + +++ + P+ +K K+E P P++ PV
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 903 KDTVQEVTKVR--RNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNKGYHK 960
K+ + K + ++ SP ++ + RS + + + + K+ K
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 961 LLTKSVAETPVHKQISKRLLHRQIKGR-SSDPGPDIGVVEESPEKGDEISLRRSPRIKQL 1019
K A+ P K+I K+ ++K + P V+E P+K +E +P+ ++
Sbjct: 801 SPLKEDAKAP-EKEIPKK---EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 1020 SFSRTHSASFYSVSQPK---------SRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLF 1070
S+ A +PK + + ++++++ ++ P +P +
Sbjct: 857 KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV-- 914
Query: 1071 GAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQT 1130
+ E P EK + K+ + ++ P+ K++ + + ++ P+T
Sbjct: 915 -EVKEDAKPKEK--TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKT 971
Query: 1131 PLYTPE---RLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQK 1177
E L K P+K K + K SS+ DS K T K
Sbjct: 972 EAKAKEDDKTLSKEPSKPKAEK------AEKSSSTDQKDSKPPEKATEDK 1015
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 70.9 bits (172), Expect = 1e-11
Identities = 152/703 (21%), Positives = 238/703 (33%), Gaps = 104/703 (14%)
Query: 798 QKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQELRTRSAKKRRK 857
+KLA + D D +E +S S +R S SP + ++RS RR+
Sbjct: 139 EKLASMKKQDEDKDKRDKEEKES--------SREKRERSRSP-----RRRKSRSPSPRRR 185
Query: 858 NALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPAPQQPSQPVKD-TVQEVTKVRRNL 916
++ +R + S++ R + A +K+ P +PS VK+ +VQE T
Sbjct: 186 SSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST---- 241
Query: 917 FNQELLSPSKRSL---KRGLPRSHSVSAVDGLEDKLDNFKKNKGYHKLLTKSVAETPV-- 971
+ L P + K P +S + + + + ++K + ++S + T
Sbjct: 242 -SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
Query: 972 -HKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFY 1030
H+ S+ R+ P P RSP ++ S + S S
Sbjct: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
Query: 1031 SVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKR 1090
S S +SRS + K +R +SP + R +SPS R +
Sbjct: 361 SSSSSRSRSPPK-------KPPKRTSSPPRKTRR------------LSPSASPPRRRHRP 401
Query: 1091 SRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPA------- 1143
S TP++S++ S +P R S T +R SPA
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE 461
Query: 1144 ----------KMTPT----KQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLE 1189
KM ++ ++ + SSS S P++ H + GE +
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE---VG 518
Query: 1190 TKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPS--------CPAPPT----SSTAQPR 1237
+ +P R + P T P SP PAPP + T PR
Sbjct: 519 RRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR 578
Query: 1238 RECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGN 1297
R TP P R P + Q + P R + P K + PKR
Sbjct: 579 RR--TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR--- 633
Query: 1298 STVTSSPPVTPKKLFTSPLCDVSKKSPFRK------SKIECPSPGELDQKEPQMSPSVAA 1351
V+ SPP + + S S RK S E SP + P P
Sbjct: 634 -RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
Query: 1352 SLSCPVP-----STPPELSQRATLDTVP------PPPPSKVGKRCRKTSDPRRSIVECQP 1400
+ S P P S+ P+ Q + T P P P K+ K + R V
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-VSSSR 751
Query: 1401 DASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGP 1443
S +P PA P+ + + SP P ++ P P
Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP 794
Score = 51.6 bits (122), Expect = 7e-06
Identities = 147/699 (21%), Positives = 236/699 (33%), Gaps = 97/699 (13%)
Query: 1107 KKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH- 1165
K K S R S +P+ R +SP+ + + S SP H
Sbjct: 151 KDKRDKEEKESSREKRERSRSPR------RRKSRSPSPRRRSSPVRRERKRSHSRSPRHR 204
Query: 1166 -DSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPS 1224
S S +K T S++ K P + T +P P + PE P
Sbjct: 205 TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPK---PEPI---PE-PK 257
Query: 1225 CPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKL 1284
P+P +S + +E P R R+ R+ +P + ++ H R+ R+ P ++
Sbjct: 258 EPSPEKNSKKEKEKEKTRP-RSRSRSKSRSRTRSRSPSHTRPRRRHRSRS-RSYSPRRRP 315
Query: 1285 KDKAIKTPKR--------PGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPG 1336
+ +P+R P S PV ++ ++ L S S +S+ P
Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375
Query: 1337 ELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPP--SKVGKRCRKTSDPRRS 1394
+ P+ + ++ S S PP R + PPP S ++ +T R S
Sbjct: 376 KRTSSPPRKTRRLSPSAS------PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
Query: 1395 IVECQPDASATPGVGTA--DSPA-AP-------TDSRDDQKGLSLSPQSPPERRGYPGPG 1444
+ + T GT +SP+ AP ++S +D+ G + S +RR Y
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
Query: 1445 LRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHP 1504
+S + S +S + S ++ +G + + S R E S
Sbjct: 490 QQSSSDSGSS---SSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRR 546
Query: 1505 GIPPSPP------SCGPG-------SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHST 1551
PSPP S P +P P R + R+ S + + P +S
Sbjct: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP 606
Query: 1552 D------SASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPAL 1605
+ASP + S PK R+ P + P++K S
Sbjct: 607 SPPPKRRTASPPP-PPKRRASPSPPPKRRVSHSPPPKQ-RSSPVTKRRSPSLSSKHRKGS 664
Query: 1606 SMPRASRSLSKPEPTYVSPPCPR-----LSHSTPGKSRGQTYICQACTPTHGPSSTPSPF 1660
S R++R P+P P PR S S P RG SS+P
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA-------------SSSPQRR 711
Query: 1661 QTDGVPWTPSPKHSGKTTPDIIK----DWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLL 1716
Q+ P + S P IK P+ R V S P S +
Sbjct: 712 QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV 771
Query: 1717 ESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRNS 1755
+S+ ++ P+ + P SPPRNS
Sbjct: 772 QSQSPSTNWSPAV---PV-----KKAKSPTPSPSPPRNS 802
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 70.5 bits (171), Expect = 2e-11
Identities = 83/339 (24%), Positives = 113/339 (33%), Gaps = 52/339 (15%)
Query: 1105 TPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPG 1164
TP + S S TT + TP P TP SP TP+ + +++P
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTP-----SPPTTTPSPPTTTTTTPPPTTTPS 1501
Query: 1165 HDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPS 1224
P + ITP T T T TP P T PP P T SP + +
Sbjct: 1502 --PPTTTPITPPASTT-----TLPPTTTPSPPTTTTTTPP---PTTT------PSPPTTT 1545
Query: 1225 CPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKL 1284
PPTS+T P +P TPP TP T P P
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTT----TPSPPTTTTPSPPTITTTTPPPTT- 1600
Query: 1285 KDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQ 1344
TP P +T T P TP T+P+ + + + P P P
Sbjct: 1601 ------TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654
Query: 1345 MSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASA 1404
+PS P +TP S T T PPP + S P ++ P +
Sbjct: 1655 TTPSP------PTTTTP---SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705
Query: 1405 TPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGP 1443
+ + T +P++ T +P PP P P
Sbjct: 1706 SSPITTTTTPSSTT-----------TPSPPPTTMTTPSP 1733
Score = 55.8 bits (133), Expect = 4e-07
Identities = 67/278 (24%), Positives = 89/278 (32%), Gaps = 31/278 (11%)
Query: 1119 TTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKR 1178
TTP + TP TP P P TP+ + +++P P + ITP
Sbjct: 1498 TTPSPPTTTPITP---PASTTTLPPTTTPSPPTTTTTTPPPTTTPS--PPTTTPITPPTS 1552
Query: 1179 HTQAGEGTSLE-----------TKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPA 1227
T T+ T TP P PP P + S P + +
Sbjct: 1553 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP 1612
Query: 1228 PPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDK 1287
PPT++ + P +TP PP P T P P
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTP--SPPPTTTTTPP---PTTTPSPPTTTTPSP 1667
Query: 1288 AIKTPKRPGNSTVTSSP----PVTPKKLFTSPLCDVSKKSPF----RKSKIECPSPGELD 1339
I T P +T SSP P P T+P + SP S PSP
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT 1727
Query: 1340 QKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPP 1377
P SP+ S +T P + + L T P PP
Sbjct: 1728 MTTP--SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP 1763
Score = 55.1 bits (131), Expect = 7e-07
Identities = 63/272 (23%), Positives = 85/272 (31%), Gaps = 37/272 (13%)
Query: 1209 NCTWPHS---VNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAA------FMG 1259
NC WP SP + + PPTS+T P +P TPP
Sbjct: 1387 NCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT 1446
Query: 1260 TPQNQTHQQPHVLRAAR-----AEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTS 1314
TP T P + P TP P +T T P TP T+
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506
Query: 1315 PLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVP 1374
P+ + + + PSP P P+ S P TPP + T P
Sbjct: 1507 PITPPASTTTLPPT--TTPSPPTTTTTTP--PPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562
Query: 1375 PPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSP 1434
PPP+ P + TP T +P+ PT + + +P P
Sbjct: 1563 SPPPT----------------TTTTPPPTTTPSPPTTTTPSPPTITTTTPPP-TTTPSPP 1605
Query: 1435 PERRGYPGPGLRSDWHASSPLLITSDTEHVTL 1466
P P ++P IT T TL
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTP--ITPPTSTTTL 1635
Score = 53.1 bits (126), Expect = 2e-06
Identities = 59/259 (22%), Positives = 81/259 (31%), Gaps = 33/259 (12%)
Query: 1190 TKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTP------ 1243
T TP P T PP P + S P + + PPT++ + P TP
Sbjct: 1419 TTTPSPPTTTTTTPP--------PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP 1470
Query: 1244 ------IRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGN 1297
P TP TP T P PA TP P
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT--TTPITPPASTTTLPPTTTPSPPTT 1528
Query: 1298 STVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPV 1357
+T T P TP T+P+ + + + P P P +PS + +
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT--- 1585
Query: 1358 PSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDAS-ATPGVGTADSPAA 1416
PS P T+ T PPP + T+ P + P + TP T P
Sbjct: 1586 PSPP-------TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638
Query: 1417 PTDSRDDQKGLSLSPQSPP 1435
T S + P + P
Sbjct: 1639 TTPSPPPTTTTTPPPTTTP 1657
Score = 47.0 bits (110), Expect = 2e-04
Identities = 120/577 (20%), Positives = 179/577 (31%), Gaps = 59/577 (10%)
Query: 1119 TTPRRISHTP-----QTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKI 1173
TT ++ TP QTP TP + TPT + ++ +P
Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTP----- 3841
Query: 1174 TPQKRHTQAGEGTSLETKTP--RTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTS 1231
TP TQ T + T T TP GTQ P P T +V +P P T+
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTT 3900
Query: 1232 STAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKT 1291
TP +TP T T P T
Sbjct: 3901 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPT 3957
Query: 1292 PKRPGNSTVTSSPPVTPKKLFTSPL---CDVSKKSPFRKSKIECPSPGELDQKEPQMSPS 1348
P G T T++P T + +P +P + P+P + P +P
Sbjct: 3958 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017
Query: 1349 VAASLSCPVPS---TPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASAT 1405
+ P P+ T + T T P P+ G + T+ P + P + T
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPT 4076
Query: 1406 PGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPG--PGLRSDWHASSPLLITSDTEH 1463
+P T + ++P P P P + +P + T
Sbjct: 4077 GTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4128
Query: 1464 VTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSP----L 1519
T ++ + V G +T + + + P+P G +P +
Sbjct: 4129 TTPITTT---------TTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPI 4178
Query: 1520 MPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKID 1579
+ V T Q A T S P +++ P +
Sbjct: 4179 TTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT-----E 4233
Query: 1580 PSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPP------CPRLSHST 1633
++ L P + E +S S A + +LS P T SPP S S
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 4293
Query: 1634 PGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPS 1670
P S QT A TPT P STPS +T G+ PS
Sbjct: 4294 PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS 4330
Score = 41.6 bits (96), Expect = 0.007
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 7/150 (4%)
Query: 1094 TLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAF 1153
T S P TP + S + TTP T TP P SP TP+
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPP-TTTTPSPPITTTTTP--PPTTTPSSPITTTPSPPTTT 1695
Query: 1154 KESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWP 1213
+ +++P SP+ + TP T + T++ T +P T T LP T
Sbjct: 1696 MTTPSPTTTPS--SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS 1753
Query: 1214 HSVNSSPESPSCPAPPTS--STAQPRRECL 1241
+ ++P PS P S ST P C+
Sbjct: 1754 SPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Score = 40.0 bits (92), Expect = 0.022
Identities = 80/331 (24%), Positives = 104/331 (31%), Gaps = 65/331 (19%)
Query: 1119 TTPRRISHTP-----QTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKI 1173
TT ++ TP QTP TP + TPT + ++ +P
Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTP----- 4140
Query: 1174 TPQKRHTQAGEGTSLETKTP--RTPKRQGTQPPGFLPNCT--------WPHSVNSSPESP 1223
TP TQ T + T T TP GTQ P P T P + P +
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH 4200
Query: 1224 SCPA----------PPTSSTAQPRRECLTPIRDP---LRTPPRAAAFMGTPQNQTHQQPH 1270
+ A PP SST Q R +P+ + L T P A T T P
Sbjct: 4201 TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 4260
Query: 1271 VLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPV--------------TPKKLFTSPL 1316
P TP R G +T +SS P TP L T +
Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSI 4319
Query: 1317 CDVSKKSPFRKSKIEC-------PSPGE--LDQKEPQMSPSVAASLSCPV-------PST 1360
+ P+ S + C +PGE + V SLSC + PST
Sbjct: 4320 IRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST 4379
Query: 1361 PPELSQRATLDTVPPPPPSKVGKRCRKTSDP 1391
P + P P S K T P
Sbjct: 4380 PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 4410
Score = 34.7 bits (78), Expect = 0.92
Identities = 43/181 (23%), Positives = 61/181 (33%), Gaps = 23/181 (12%)
Query: 1504 PGIPPSPPSCGPGSPLM-PSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVE 1562
P PSPP+ P P PS TT + P + ST + P T
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT---- 1521
Query: 1563 LEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYV 1622
+ P P ++ + P + + + LP + P P PT
Sbjct: 1522 -----TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP-------SPPPTTT 1569
Query: 1623 SPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVP----WTPSPKHSGKTT 1678
+ P P + S P + TP P++TPSP T TPSP + T
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPP--PTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627
Query: 1679 P 1679
P
Sbjct: 1628 P 1628
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 67.0 bits (162), Expect = 2e-10
Identities = 153/623 (24%), Positives = 208/623 (33%), Gaps = 152/623 (24%)
Query: 1125 SHTPQTPLYT-------------PERLQKSPAKMTPTK----QAAFKESLKDSSSPGHDS 1167
SH+PQ PL + P LQ PA +T + L+ +S+P
Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556
Query: 1168 PLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWP--HSVNSSPESPSC 1225
L++ P QA + L T P TP T PP P P + S P SP
Sbjct: 557 HLETPPCPAPCPLQAPP-SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615
Query: 1226 PAPPTSSTAQPRRECLTPIR---DPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQ 1282
PP + P L P++ P +PP + +PQ H+L+A + P+
Sbjct: 616 TPPPQA----PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 1283 KLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKE 1342
++ P P S + P P L PL + P PSP
Sbjct: 672 PVQ-APFSPPASPPVSPSATPPSQAPPSLAAPPL-----QVP--------PSP----PAS 713
Query: 1343 PQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDA 1402
P MSPS + P P PP L+ A VPP PP+ T PR P
Sbjct: 714 PPMSPS-----ATPPPQAPPPLA--APPLQVPPSPPASPPMSPSATPPPR------VPPL 760
Query: 1403 SATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTE 1462
A P + SP A L +SP + P + P ++P L +
Sbjct: 761 LAAPPLQVPPSPPA---------SLPMSPLAKPPPQAPPA--------LATPPLQALPSP 803
Query: 1463 HVTLLSEAEHHGIGDLKSNVLSVEEGEG----------LRTADAEKSSLSHPGIPPSPP- 1511
+ +A L + L+ + + + +L P PP+P
Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863
Query: 1512 -----------SCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYE 1560
+ PG P PSR T G P A HS+ + S
Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSG------------PDLAGHSSSATSTPE-- 909
Query: 1561 VELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPT 1620
EL SG P A P E L A SR + P
Sbjct: 910 -ELRGYDSG----------PEGGAAASPPPDAE--------LAACHPAAWSRGPAPPLAF 950
Query: 1621 YVSP--PCPRLSHSTPGKSRGQTYICQACTPTHGP-SSTPSPFQTDGVPWTPSPKHSGKT 1677
+P P P + PG + G I + T GP S+TP+P D PSP SG
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYE----TEGPESATPAPGALDP---GPSPGTSG-- 1001
Query: 1678 TPDIIKDWPRRKRAVGCGAGSSS 1700
K A G GAG+SS
Sbjct: 1002 ----------GKAAAGAGAGASS 1014
Score = 65.9 bits (159), Expect = 4e-10
Identities = 131/558 (23%), Positives = 195/558 (34%), Gaps = 94/558 (16%)
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT 1195
E + + A P + A + +D+S P +P + +R AG L P
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA---RRSRAAGTEVGLPRPAPSA 196
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR------RECLTPIRDPLR 1249
R T+ P + HS ++ SP+ P++ R TP+ P R
Sbjct: 197 RPRPPTEGPRKSVSSASEHS--TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 1250 TPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPK 1309
+ P A P + + +P L+A R + KD A P ++SSP TP
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA------PALGPLSSSPLATP- 307
Query: 1310 KLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRAT 1369
SP ++ P P P L P +P L+ P PS PP L T
Sbjct: 308 ----SPSGTKARPVP-PPDNAATPLPATLPPSPPLATP---LPLAPPSPSAPPSLQ---T 356
Query: 1370 LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSL 1429
L + P PPS+ T+ P ++ P P + S +P
Sbjct: 357 LPSPPATPPSQAPP--SMTTPP----MQAPPSLQTIPPIQVPHSLTSP------------ 398
Query: 1430 SPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLS---EAEHHGIGDLKSNVLSVE 1486
S Q+PP SPL ++S +L S +A H + +S
Sbjct: 399 SLQAPP-----------------SPLALSSLQATTSLGSPTLQATHSFL------TMSPR 435
Query: 1487 EGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPAS 1546
+ + T+ + +S P SPP P S L S + + S+ L P
Sbjct: 436 QTQASLTSPSRPASTP----PDSPPLQAPLS-LPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 1547 AWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALS 1606
A S S SPQ + + +P L + SL+ P S L LP+L+
Sbjct: 491 ALSSLASHSPQA-----PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN---LPSLA 542
Query: 1607 MP---RASRSLSKP--EPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQ 1661
P AS L+ P E PCP + +P + TP P P
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP---PPQAPPALA 599
Query: 1662 TDGVPWTPSPKHSGKTTP 1679
+ + PSP S TP
Sbjct: 600 SPPLQGLPSPPLSPLATP 617
Score = 32.0 bits (71), Expect = 5.9
Identities = 72/325 (22%), Positives = 101/325 (31%), Gaps = 56/325 (17%)
Query: 1128 PQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTS 1187
P P P +P P AA L+ SP P+ P + A
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAA--PPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
Query: 1188 LETKTPRTPKRQGTQPPGFLPNCTWPHS--VNSSPESPSC---------PAPPTSSTAQP 1236
L+ P P Q P F P+ + P S P++P P+PP S T Q
Sbjct: 797 LQA-LPSPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 1237 RRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPG 1296
R TP D + PR + A P + + P G
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLAL---------------APGPPPPPSRSPSSTLSGPDLAG 899
Query: 1297 NSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCP 1356
+S SS TP++L + P G P + +
Sbjct: 900 HS---SSATSTPEEL---------------RGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Query: 1357 VPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTAD---S 1413
PP + A +P PP + G ++D +I E + SATP G D S
Sbjct: 942 RGPAPPLAFRGAPGAPLPWPPATGPG-----SADGLCTIYETEGPESATPAPGALDPGPS 996
Query: 1414 PAAPTDSRDDQKGLSLSPQSPPERR 1438
P G S +SP + R
Sbjct: 997 PGTSGGKAAAGAGAGASSRSPKQAR 1021
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 64.3 bits (155), Expect = 1e-09
Identities = 184/833 (22%), Positives = 291/833 (34%), Gaps = 156/833 (18%)
Query: 1129 QTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSL 1188
++PL P ++SP P A + S SP P +S ++P ++ +
Sbjct: 605 ESPLSPPP--EESPLSPPPE---ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659
Query: 1189 ETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSP---ESPSCPAPPTSSTAQPRRECLTPI- 1244
+P + + PP P P + SP +SP+ P P S + P + L +
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP 719
Query: 1245 ----------RDPLRTPPRAAAFMGTPQNQTH-----QQPHVLRAARAEEP---AQKLKD 1286
+P P + + H ++PH+ + +AEEP Q +
Sbjct: 720 LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL--SPQAEEPHLSPQPEEP 777
Query: 1287 KAIKTPKRPGNSTVTSSPPVTPK--KLFTSPLCDVSKKSPFRKSKIECPSPGEL----DQ 1340
P+ P S P ++P+ +L SP + SP + P P E
Sbjct: 778 CLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837
Query: 1341 KEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQP 1400
+EP +SP S P PP LS R P PP + G+ C + +P
Sbjct: 838 EEPCLSPRPEESHLSPELEKPP-LSPR------PEKPPEEPGQ-CPAPEELPLFPPPGEP 889
Query: 1401 DASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSD 1460
S G P P S ++ L LSP P P SP++ +
Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEE-LPLSPSGEPSLSPQLMPPDPLP-PPLSPIITAAA 947
Query: 1461 TEHVTLLSEAEH----HGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPS--PPSCG 1514
++ L E E+ G D +S L+ E + E + +PP PPS
Sbjct: 948 PPALSPLGELEYPFGAKGDSDPESP-LAAPILETPISPPPEANCTDPEPVPPMILPPS-- 1004
Query: 1515 PGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKL- 1573
PGSP+ P+ + QC Q +P ++ S SP + + S + K+
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS--QCSPPALPLSVPSPLSPIGKVV 1062
Query: 1574 RIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHST 1633
+ +E E +S+ E E S L P S P P L T
Sbjct: 1063 GVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDT 1122
Query: 1634 PGKSRGQTYICQACTPTHG---PSSTPSPFQTDGV--------PWTPSPKHSGKTTPDII 1682
P G P S P P QT G P P+ TP +
Sbjct: 1123 --------------APLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTP--M 1166
Query: 1683 KDWPRRKRAVGCGAG---------------------------SSSGRGEVGADLPGSLSL 1715
+ +P K+ G G+ S+ +G+ A PGS L
Sbjct: 1167 EVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPL 1226
Query: 1716 LESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRN---------SMPKAEEASSWG 1766
L S + G LS+ GV D SP R+ S+P+ +++
Sbjct: 1227 LGSPDPEGGGSLSMEL----------GVST--DVSPARDEGSLRLCTDSLPETDDSLL-- 1272
Query: 1767 QFGLSSRKRVLLAKEEADRGAKRICDLREDSEVSKSKEG-SPSWSAWQLPSTGDEEVFVS 1825
+ + K E ++G +R R S+ K+G S S+ + P G
Sbjct: 1273 ---CDAGTAISGGKAEGEKGRRRSSPAR-----SRIKQGRSSSFPGRRRPRGG-----AH 1319
Query: 1826 GSTPPPSCAVRSCLSASALQALTQSPLLFQGKTPSSQSKDPRDEDVDVLPSTV 1878
G ++S +AS+++ L + + SS SK+ +ED D + +TV
Sbjct: 1320 GGRGRGRARLKS--TASSIETLVVADI------DSSPSKEEEEEDDDTMQNTV 1364
Score = 52.8 bits (125), Expect = 3e-06
Identities = 176/793 (22%), Positives = 253/793 (31%), Gaps = 111/793 (13%)
Query: 955 NKGYHKLLTKS-VAETPVHKQISKRL-LHRQIKGRSSDPGPDIGVVEESPEKGDEISLRR 1012
+KGYH K + E P H K + R S++ P+ E +
Sbjct: 295 DKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQG 354
Query: 1013 SPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGA 1072
I+ ++ T S +S +P + Q + V S++ + G
Sbjct: 355 GQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP---GP 411
Query: 1073 MSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTP----RRISHTP 1128
+ P K +++ + L+ E+P + S T+P R+S P
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPP 471
Query: 1129 Q----TPLYTPERLQKS-PAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAG 1183
+ +PL PE L S P + +P + L SPL+ +P ++
Sbjct: 472 EELPASPL--PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEE--SPLSPPEESP 527
Query: 1184 EGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTP 1243
+LET P+ PP SP SP PTS + R P
Sbjct: 528 PSPALETPLSPPPEASPLSPP-----------FEESPLSPPPEELPTSPPPEASRLSPPP 576
Query: 1244 IRDPLRTPPRAAAFMGTPQNQTHQQP---HVLRAARAEEP------AQKLKDKAIKTPKR 1294
P+ PP + P+ P L E P A +L +P
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Query: 1295 PGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP----QMSPSVA 1350
P SPP +L SPL VS+ SP + P P E P ++SP
Sbjct: 637 PPPEESPMSPPPEVSRL--SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPE 694
Query: 1351 ASLSCPVP-----STPPELS-QRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASA 1404
S + P P S PPE S L+ P P + + C ++ P S +P S
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 1405 TPGVGTADSPAAP---TDSRDDQKGLSLSPQSPPERRGYPGPGLR---SDWHAS----SP 1454
P SP A + ++ L P+ P GP L + H S P
Sbjct: 755 RPEEPHL-SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 1455 LLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLS--------HPG- 1505
L E E H + LS E + + EK LS PG
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 1506 ----------IPPSPPSCGP-----------GSPLMPSRDVHCTTDGRQCQASAQL---D 1541
PP PS P PL P + + + S QL D
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD 933
Query: 1542 NLPASAWHSTDSASPQTY----EVELEMQASGLPKLRIKKIDPSSSLEA----EPLS--K 1591
LP +A+P E+E A G DP S L A P+S
Sbjct: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKG-------DSDPESPLAAPILETPISPPP 986
Query: 1592 EESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTH 1651
E + E P + P + P + P P+ S Q C+P
Sbjct: 987 EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPA 1046
Query: 1652 GPSSTPSPFQTDG 1664
P S PSP G
Sbjct: 1047 LPLSVPSPLSPIG 1059
Score = 51.2 bits (121), Expect = 9e-06
Identities = 179/811 (22%), Positives = 269/811 (33%), Gaps = 144/811 (17%)
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQ-KRHTQAGE------GTSL 1188
+++ K K+ +A + + KD+ + + + + Q + T+ G+ +L
Sbjct: 2043 KQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPAL 2102
Query: 1189 ETKTPRTPKRQGTQPPG-----FLPNCTWPHSVNSS------PESPSCPAPPTSSTA--- 1234
+ P P G+ PP F+ + T P +++S P + S P P +
Sbjct: 2103 HLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLK 2162
Query: 1235 -QPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPK 1293
P+ P +DP P A+ P+ T + + PAQ A P
Sbjct: 2163 LPPQVPAQVPSQDPFGLAP---AYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219
Query: 1294 RPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAAS- 1352
++PP TP+ ++P PF K + CPS LD SP V
Sbjct: 2220 AGQPGEFHTTPPGTPRHQPSTP-------DPFLKPR--CPS---LDNLAVPESPGVGGGK 2267
Query: 1353 LSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVG--T 1410
S P+ S PP R L+ ++G P V+ + G+ T
Sbjct: 2268 ASEPLLSPPPFGESRKALEV----KKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 1411 ADSPAAPTDSRDDQ-----KGLSLSPQSPPERRG-------YPG---PGLRSDWHASSPL 1455
D AP R Q GL L PQ PP + +P PG +D +A PL
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383
Query: 1456 -------------------LITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADA 1496
L + V +++ L LS E
Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR 2443
Query: 1497 EKSSLSHPGIPPSPPSCGPGSPL----MPSRDVHCTTDGRQCQASAQLDNLPASAWHSTD 1552
+S + P P S P +PL P G S PA
Sbjct: 2444 FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPA------- 2496
Query: 1553 SASPQTYEVELEMQA-SGLPKLRIKKID-------PSSSLEAEPLSKEESSLGEESFLPA 1604
A P EL + SG P ++ PS P + E SL P
Sbjct: 2497 -ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
Query: 1605 LSMPRASRSLSKPEPTYVSPPCPRLSHSTP---------GKSRGQTYICQACTPTHGPSS 1655
L P S P PT P + +T G S G T +P PS
Sbjct: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV 2615
Query: 1656 TPSPFQTDGVPWTP--SPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEV-GADLPGS 1712
P P +P+ + + SG T+P ++ G G GSS E+ G PG
Sbjct: 2616 LPPPAPDGSLPYLSHGASQRSGITSP------VEKREDPGTGMGSSLATAELPGTQDPGM 2669
Query: 1713 LSLLESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRNSMPKAEE-----ASSWGQ 1767
L ++E LE R + E L Q RN++ + +E A + G
Sbjct: 2670 SGLSQTE-----LEKQRQRQRLRE--------LLIRQQIQRNTLRQEKETAAAAAGAVGP 2716
Query: 1768 FGLSSRKRVLLAKEEADRGAKRICDLREDSE---VSKSKEGSPSWSAWQLPSTGDEEVFV 1824
G + A E+ RG ++ S + SK P PS D+ +
Sbjct: 2717 PGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPS--DDRL-- 2772
Query: 1825 SGSTPPPSCAVRSCLSASALQALTQSPLLFQ 1855
S PPP A S + ++ Q + S +Q
Sbjct: 2773 --SRPPPP-ATPSSMDVNSRQLVGGSQAFYQ 2800
Score = 42.4 bits (98), Expect = 0.004
Identities = 86/376 (22%), Positives = 126/376 (33%), Gaps = 74/376 (19%)
Query: 1128 PQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQ----KRHTQAG 1183
PQ P P + P + P + + P + SP + P AG
Sbjct: 2165 PQVPAQVPSQ---DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
Query: 1184 EGTSLETKTPRTPKRQGTQPPGFL-PNCTWPHSVNSSPESPSCP---------APPTSST 1233
+ T P TP+ Q + P FL P C ++ + PESP +PP
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNL-AVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 1234 AQPRRECLTP---IRDPLRTPPRAAAFMGTPQNQTH------------QQPHVLRAARAE 1278
++ E P PP F+ +P + TH + P RA++ E
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPN-LGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE 2339
Query: 1279 -------------EPAQKLKDKAIKTPK--RPGNST-VTSSPPVTPKKLFTSP--LCDVS 1320
PAQ L P RPG+ T + PP+TP+ P C +
Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP 2399
Query: 1321 KKS----PFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPP 1376
+S PF S++ + + P ++A CP P TP S P P
Sbjct: 2400 PRSLPSDPF--SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS--------PDP 2449
Query: 1377 ---PPSKVGKR-----CRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLS 1428
PPS+ R K P+ V + + A +G PAA +
Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK 2509
Query: 1429 LSPQSPPERRGYPGPG 1444
+ PP PG G
Sbjct: 2510 VPSGQPPNFVRSPGTG 2525
Score = 35.8 bits (81), Expect = 0.41
Identities = 44/166 (26%), Positives = 59/166 (35%), Gaps = 12/166 (7%)
Query: 1510 PPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASG 1569
PP P SP P + + + S + LPAS S E L
Sbjct: 443 PPEESPLSP--PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500
Query: 1570 LPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKP-EPTYVSPPCPR 1628
P + P S LE PLS E S + LS P + LS P E + +SPP
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560
Query: 1629 LSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHS 1674
L S P +A + P +P + P +P P+ S
Sbjct: 561 LPTSPPP---------EASRLSPPPEESPMSPPPEESPMSPPPEAS 597
Score = 32.0 bits (71), Expect = 5.9
Identities = 50/187 (26%), Positives = 70/187 (37%), Gaps = 14/187 (7%)
Query: 1497 EKSSLSHPGIPPSPPSCGPGSPLMPSRDVH-CTTDGRQCQASAQLDNLPASAWHSTDSAS 1555
E+S LS P SPPS +PL P + + + S + LP S S
Sbjct: 516 EESPLSPP--EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573
Query: 1556 PQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLG---EESFLPALSMPRASR 1612
P E + S P+ P +S P EES L EES P P ASR
Sbjct: 574 PPPEESPM----SPPPEESPMSPPPEASRLFPPF--EESPLSPPPEES--PLSPPPEASR 625
Query: 1613 SLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPK 1672
PE + +SPP S P + + + + P +P + P +P P+
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE 685
Query: 1673 HSGKTTP 1679
S + P
Sbjct: 686 ASRLSPP 692
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 62.8 bits (151), Expect = 3e-09
Identities = 137/618 (22%), Positives = 200/618 (32%), Gaps = 124/618 (20%)
Query: 1136 ERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT 1195
E + + A P + A + +D+S P +P + +R AG L P
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA---RRSRAAGTEVGLPRPAPSA 196
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR------RECLTPIRDPLR 1249
R T+ P + HS ++ SP+ P++ R TP+ P R
Sbjct: 197 RPRPPTEGPRKSVSSASEHS--TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 1250 TPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPK 1309
+ P A P + + +P L+A R + KD A P ++SSP TP
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA------PALGPLSSSPLATPS 308
Query: 1310 KLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQM-----SPSVAASLSCPVPSTPPEL 1364
PS Q P + S S+ L+ P+P PP
Sbjct: 309 -----------------------PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 1365 SQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQ 1424
S +L T+P PP + + P + + T A P
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP------- 398
Query: 1425 KGLSLSP-QSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVL 1483
L+L P Q+PP P SPL S N L
Sbjct: 399 -ALALPPLQAPPSPPASP---------PLSPLATPSPQ-----------------APNAL 431
Query: 1484 SVEEGEGLRTADAEKSSLSHP-GIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDN 1542
+V L P PPSPP P SP P+ + QA L
Sbjct: 432 AVH-------------LLQAPFSPPPSPPVQAPFSP--PASPPVSPSATPPSQAPPSLAA 476
Query: 1543 LPASAWHSTDSASPQTYEVELEMQAS---GLPKLRIKKIDPSS--SLEAEPL----SKEE 1593
P S ++ P + QA P L++ K P + +L PL S
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 536
Query: 1594 SSLGEESFLPALSMPRASRSLSKPE-------PTYVSPPCPRLSHS--------TPG--K 1636
S G+ F P+ S+P + + P+ P PP P S + TPG
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
Query: 1637 SRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPDIIKDWPRRKRAVGCGA 1696
S + A P P + SP T P S +TP+ ++ + G A
Sbjct: 597 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE--GGAA 654
Query: 1697 GSSSGRGEVGADLPGSLS 1714
S E+ A P + S
Sbjct: 655 ASPPPDAELAACHPAAWS 672
Score = 36.2 bits (82), Expect = 0.32
Identities = 84/389 (21%), Positives = 119/389 (30%), Gaps = 78/389 (20%)
Query: 1078 SPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPER 1137
SP A ++ N L + A +P S FS +S + P P
Sbjct: 414 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473
Query: 1138 LQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPK 1197
L P ++ P+ A+ SP P PQ A L P+ P
Sbjct: 474 LAAPPLQVPPSPPAS------PPMSPSATPP------PQAPPPLAAPPLQLAKPPPQAPP 521
Query: 1198 RQGTQP-----------PG---FLPNCTWPHS--VNSSPESPSC---------PAPPTSS 1232
T P PG F P+ + P S P++P P+PP S
Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581
Query: 1233 TAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTP 1292
T Q R TP D + PR + A P + + P
Sbjct: 582 TLQAPRRPPTPGPDTSVSGPRLTLAL---------------APGPPPPPSRSPSSTLSGP 626
Query: 1293 KRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAAS 1352
G+S SS TP++L + P G P +
Sbjct: 627 DLAGHS---SSATSTPEEL---------------RGYDSGPEGGAAASPPPDAELAACHP 668
Query: 1353 LSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTAD 1412
+ PP + A +P PP + G ++D +I E + SATP G D
Sbjct: 669 AAWSRGPAPPLAFRGAPGAPLPWPPATGPG-----SADGLCTIYETEGPESATPAPGALD 723
Query: 1413 ---SPAAPTDSRDDQKGLSLSPQSPPERR 1438
SP G S +SP + R
Sbjct: 724 PGPSPGTSGGKAAAGAGAGASSRSPKQAR 752
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 60.1 bits (144), Expect = 2e-08
Identities = 90/372 (24%), Positives = 129/372 (34%), Gaps = 21/372 (5%)
Query: 1071 GAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQT 1130
GAMS SP+ S + RS + P+ T S S+S T+P +++P +
Sbjct: 1587 GAMSPSYSPT---SPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSP---NYSPTS 1640
Query: 1131 PLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLET 1190
P Y+P SP + + + S SP SP S +P T + +
Sbjct: 1641 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPTSPS 1698
Query: 1191 KTPRTPKRQGTQPPGFLPNCTW-PHSVNSSPESPS-CPAPPTSSTAQPRRECLTPIRDPL 1248
+P +P T P + ++ P S + SP SPS P P+ S P +P P
Sbjct: 1699 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPT 1758
Query: 1249 RTP--PRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPV 1306
P + ++ T N T P+ + + P + SP
Sbjct: 1759 SPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTY 1818
Query: 1307 TPKKLFTSPLC-DVSKKSP--FRKSKIECPSPGELDQKEPQMSP-SVAASLSCPVPSTPP 1362
TP SP S SP S PS E P+ SP S S + P S
Sbjct: 1819 TPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTS 1878
Query: 1363 ELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRD 1422
T P P + P+ S P + SP +PT S
Sbjct: 1879 PTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYS-----PTSPTYSPTSPKYSPTSPTYSPT 1933
Query: 1423 DQKGLSLSPQSP 1434
KG + SP SP
Sbjct: 1934 SPKGSTYSPTSP 1945
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/376 (23%), Positives = 129/376 (34%), Gaps = 30/376 (7%)
Query: 1057 SPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSF 1116
SP SP S + S SP+ + T S P T S S+
Sbjct: 1616 SPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSP----TSPSYSPTSPSY 1671
Query: 1117 SKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQ 1176
S T+P S++P +P Y+P SP + + + S SP SP S +P
Sbjct: 1672 SPTSP---SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPS 1726
Query: 1177 KRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPS-CPAPPTSSTAQ 1235
T + + +P +P T PN T P S + SP SPS P P +
Sbjct: 1727 YSPTSPSYSPTSPSYSPTSPNYSPTS-----PNYT-PTSPSYSPTSPSYSPTSPNYTPTS 1780
Query: 1236 PRRECLTPIRDPLRT--PPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIK--T 1291
P +P P P + ++ + T Q P ++ + P+ T
Sbjct: 1781 PNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYT 1840
Query: 1292 PKRPGNSTVTSSP---PVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPS 1348
P P S SSP P +PK TSP + S P+ + P SP+
Sbjct: 1841 PTSPSYS--PSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPT 1898
Query: 1349 VAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGV 1408
S T P+ S + + P S TS + P S T
Sbjct: 1899 -----SPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPT 1953
Query: 1409 GTADSPAAPTDSRDDQ 1424
+ SPA D D++
Sbjct: 1954 YSLTSPAISPDDSDEE 1969
Score = 47.0 bits (110), Expect = 2e-04
Identities = 59/234 (25%), Positives = 82/234 (35%), Gaps = 32/234 (13%)
Query: 1013 SPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGA 1072
SP S + T ++ YS + P S+ + SP S SP +
Sbjct: 1745 SPNYSPTSPNYTPTSPSYSPTSP---------SYSPTSPNYTPTSPNYSPTSPS---YSP 1792
Query: 1073 MSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPL 1132
S SP+ + R + P++ S S + K TP S++P +P
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852
Query: 1133 YTPERLQKSPA--KMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLET 1190
YTP + SP K +PT S SP S TP+ T +
Sbjct: 1853 YTPTSPKYSPTSPKYSPT-----------SPKYSPTSPTYSPTTPKYSPTSPTYSPTSPV 1901
Query: 1191 KTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPS-CPAPPTSSTAQPRRECLTP 1243
TP +PK T P P S SP SP+ P P ST P +P
Sbjct: 1902 YTPTSPKYSPTSP------TYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSP 1949
Score = 38.1 bits (87), Expect = 0.083
Identities = 67/324 (20%), Positives = 105/324 (32%), Gaps = 28/324 (8%)
Query: 1127 TPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGT 1186
TP ++P + +P A+ + SPG SP + + G
Sbjct: 1540 TPGAAGFSPSAASDASG-FSPGYSPAWSPTPGSPGSPGPSSP----------YIPSPGGA 1588
Query: 1187 SLETKTPRTPKRQGTQPPGFLPNCT--WPHSVNSSPESPS-CPAPPTSSTAQPRRECLTP 1243
+ +P +P + P G+ P P S + SP SPS P P S P +P
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSP 1648
Query: 1244 IRDPLRT--PPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIK--TPKRPGNS- 1298
P P + ++ T + + P + + P +P P S
Sbjct: 1649 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1708
Query: 1299 TVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVP 1358
T S P +P TSP + S S P+ P +P+ + S S P
Sbjct: 1709 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPT-SPSYSPTSP 1767
Query: 1359 S--------TPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGT 1410
S TP + T + P PS + R + ++P
Sbjct: 1768 SYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSP 1827
Query: 1411 ADSPAAPTDSRDDQKGLSLSPQSP 1434
+ +PT + S SP SP
Sbjct: 1828 SSPSYSPTSPKYTPTSPSYSPSSP 1851
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 57.4 bits (137), Expect = 1e-07
Identities = 165/862 (19%), Positives = 294/862 (34%), Gaps = 74/862 (8%)
Query: 1032 VSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRS 1091
VS P S S S ++++++ + S S + GA S EK A +K
Sbjct: 78 VSDPISTSES---SEEEEEAEAETAKATPRLASTNSSVLGADLPS-SMKEKAKAETEKAG 133
Query: 1092 RNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKS-PAKMTPTKQ 1150
+ PA +T +L K+ + + T L + + S PA K
Sbjct: 134 KTGNSMPHPATGKTVA-----NLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP 188
Query: 1151 AAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNC 1210
DSSS S D K + + + T +P R+ PG + +
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV 248
Query: 1211 TWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPH 1270
T P+ PP +P E + + + A A GT ++Q
Sbjct: 249 T--------PQVKGGALPPAKRAKKPEEESESS-EEGSESEEEAPA--GT-RSQVKASEK 296
Query: 1271 VLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
+L+ A PA+ K TP PG + +S K S S S+
Sbjct: 297 ILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQTKAGKPEEDSE----SSSEESSDSEE 351
Query: 1331 ECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSD 1390
E P+ L Q + S + S P +P + P PP K G K
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRK--------GAAPAPPGKTGPAVAKAQA 403
Query: 1391 PRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWH 1450
+R + Q + + A + A P+ + S + P + P P ++
Sbjct: 404 GKRE-EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 1451 ASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEE-GEGLRTADAEKSSLSHPGIPPS 1509
A+ + + + + E++ N V+ G+ + A + G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 1510 PPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDN----LPASAWHSTD-------SASPQT 1558
P G P PS V + + + D+ +P + + + A P +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 1559 YEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLP-ALSMPRASRSLSKP 1617
+ Q +G +++K P + E+ S+E S + P A++ +A +L P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSES---SEESSDSADSEEAPAAMTAAQAKPALKIP 639
Query: 1618 EPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKT 1677
+ + CP+ +++T + G +++P+ T P +
Sbjct: 640 Q----TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS 695
Query: 1678 TPDIIKDWPRRKRAVGCGAGSSSGRG-EVGADLPGSLSLLESEGKDHGLELSIHRTPILE 1736
+ + + + AV G S G+G +V A S+ + S G+ L P +
Sbjct: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKA---ASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 1737 DFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLRED 1796
+ E + D E A+S Q S +K A A R +
Sbjct: 753 QVKAE---KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 1797 SEV----SKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPL 1852
+V +++K+ SPS + + + V G PS A+A QA T
Sbjct: 810 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP-- 864
Query: 1853 LFQGKTPSSQSKDPRDEDVDVL 1874
+ + SS+ + +E+ + L
Sbjct: 865 --EEDSGSSEEESDSEEEAETL 884
Score = 54.3 bits (129), Expect = 1e-06
Identities = 169/763 (22%), Positives = 266/763 (34%), Gaps = 105/763 (13%)
Query: 991 PGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDK 1050
P +G EE E E S S + + S ++ Q K S K
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-------SPAK 586
Query: 1051 SDQRENSPVQ-SIRSPKSLLFGAMSEMISPS----EKGSARMKKRSRNTLDSEVPAAYQT 1105
++ PV +++ K + SE S S E +A +++ L ++P
Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL--KIPQTKAC 644
Query: 1106 PKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
PKK++ + + +K P R+ T SPA +P + +DSSS
Sbjct: 645 PKKTN--TTASAKVAPVRVGTQAPRKAGTAT----SPAGSSPAVAGGTQRPAEDSSSSEE 698
Query: 1166 DSPLDSKITPQKRHTQAGE-GTSLETKTPRTPKR----QGTQPPGFLPNCTWPHSVN--- 1217
+ K QA G L+ K P + QGT P LP T P
Sbjct: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP--VLPGKTGPTVTQVKA 756
Query: 1218 ---SSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRA 1274
ES + + A P + + + + P AA + V A
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 1275 ARAEEPAQKLKDKAIKTPKRPGNSTVTS----SPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
A+A+ Q+ K + P NSTV + S P K + T+ + S+
Sbjct: 817 AQAK---QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 1331 ECPSPGE---LDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGK---R 1384
E S E L Q +P + P +P + P PP K G +
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK--------GAAPTPPGKTGPSAAQ 925
Query: 1385 CRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPG 1444
K D S E D A V +A P D + + +P + + P
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1445 -LRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSH 1503
R+ + S+ E V ++ GI ++NV+++ +H
Sbjct: 986 KARASESTARSSSSESEDEDVIPATQCLTPGI---RTNVVTMPT--------------AH 1028
Query: 1504 PGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASA-QLDNLPASAWHSTDSASPQTYEVE 1562
P I P G S SR +DG++ + A Q+D SA + + SPQ+ V
Sbjct: 1029 PRIAPKASMAGASSSKESSR----ISDGKKQEGPATQVD----SAVGTLPATSPQSTSV- 1079
Query: 1563 LEMQASGLPKLRIKKID--------PSSSLEAEPLSKEESSLGEESFLPALSMPRASRSL 1614
QA G KLR K+ P SS ++E S +SS G E +++ +L
Sbjct: 1080 ---QAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS--DSSSGSEEDGEGPQGAKSAHTL 1134
Query: 1615 SKPEP----TYVSPPCPRLSHS---TPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
P P T V S P +S Y+ TP + +S +P + D P
Sbjct: 1135 VGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATP-KLDSSP- 1192
Query: 1668 TPSPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLP 1710
+ S + K PD K + ++A G + + G+ P
Sbjct: 1193 SVSSTLAAKDDPD-GKQEAKPQQAAGMLSPKTGGKEAASGTTP 1234
Score = 40.8 bits (94), Expect = 0.013
Identities = 168/851 (19%), Positives = 287/851 (33%), Gaps = 122/851 (14%)
Query: 829 SSARRSVSGSPESDELQELRTRSAKKRR--KNALIRHKSIAEVSQNLRQIEIPKVSKRAT 886
SS V G P Q + + K + A + +V+ ++ +P +KRA
Sbjct: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP-AKRAK 264
Query: 887 KKENSHPAPQQPSQPVKD----TVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAV 942
K E + ++ S+ ++ T +V + L + +P+K G P + A
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAK-----GTPGKGATPAP 319
Query: 943 DGLEDKLDNFKK-------NKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDI 995
G + + K ++ + + S ETP +K LL + G++S G
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA----AKALLQAKASGKTSQVGAAS 375
Query: 996 GVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRE 1055
+ESP KG + P + ++ + SQ S ++SD E
Sbjct: 376 APAKESPRKG---AAPAPPGKTGPAVAKAQAGKREEDSQSSS-----------EESDSEE 421
Query: 1056 NSPVQSIRSPKSLLFGAMSEMISPS-EKGSARMKKRSRNTLDSEVPAAYQ------TPKK 1108
+P Q+ S K+ A S S KG+A R ++V Q + ++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
Query: 1109 SHQKSLSFSKTTPRRISHTPQTPLYTPERLQ-----------KSPAKMTPTKQAA----- 1152
S + + ++ ++P P P K+ P +A
Sbjct: 482 SDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW 541
Query: 1153 --FKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPG----- 1205
ES + SS D + + + P + + G L+ K +P + Q G
Sbjct: 542 EEDSESSSEESSDSSDGEVPTAVAPAQ---EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ 598
Query: 1206 -----FLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
+ N + S +S PA T++ A+P + P +T A+A +
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV-A 657
Query: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS 1320
P Q P +A A PA A T +RP + +S + ++ +
Sbjct: 658 PVRVGTQAPR--KAGTATSPAGSSPAVAGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQ 714
Query: 1321 KKSPFRKSKIEC---PSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDT---VP 1374
KS + +++ P G L Q + P V + E S+ + ++
Sbjct: 715 AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 1375 PPPPSKVGKRCRKTSDPRRSIVECQPDASATPGV-GTADSPAAPTDSRDDQKGLSLSPQS 1433
P++V +KT + P A+ P GT +P + K S S
Sbjct: 775 AASPAQVKTSVKKTQ------AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAE---HHGIGDLKSNVLSVEEGEG 1490
PP R L A P + S + V ++A+ G + S EE E
Sbjct: 829 PPVRNPQNSTVL-----ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 1491 L------------RTADAEKSSLSHPGIPPSPP-SCGPGSPLMPSRDVHCTTDGRQCQAS 1537
L R A A G P+PP GP + +D D
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD-----DSGSSSEE 938
Query: 1538 AQLDNLPASAWHSTDSASPQTYEVELEMQASG---LPKLRIKKIDPSSSLEAEPLSKEES 1594
+ D +A S P V+ +G P P + +E ++ S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
Query: 1595 SLGE-ESFLPA 1604
S E E +PA
Sbjct: 999 SESEDEDVIPA 1009
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 57.4 bits (137), Expect = 1e-07
Identities = 165/862 (19%), Positives = 294/862 (34%), Gaps = 74/862 (8%)
Query: 1032 VSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRS 1091
VS P S S S ++++++ + S S + GA S EK A +K
Sbjct: 78 VSDPISTSES---SEEEEEAEAETAKATPRLASTNSSVLGADLPS-SMKEKAKAETEKAG 133
Query: 1092 RNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKS-PAKMTPTKQ 1150
+ PA +T +L K+ + + T L + + S PA K
Sbjct: 134 KTGNSMPHPATGKTVA-----NLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP 188
Query: 1151 AAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNC 1210
DSSS S D K + + + T +P R+ PG + +
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV 248
Query: 1211 TWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPH 1270
T P+ PP +P E + + + A A GT ++Q
Sbjct: 249 T--------PQVKGGALPPAKRAKKPEEESESS-EEGSESEEEAPA--GT-RSQVKASEK 296
Query: 1271 VLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
+L+ A PA+ K TP PG + +S K S S S+
Sbjct: 297 ILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQTKAGKPEEDSE----SSSEESSDSEE 351
Query: 1331 ECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSD 1390
E P+ L Q + S + S P +P + P PP K G K
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRK--------GAAPAPPGKTGPAVAKAQA 403
Query: 1391 PRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWH 1450
+R + Q + + A + A P+ + S + P + P P ++
Sbjct: 404 GKRE-EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 1451 ASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEE-GEGLRTADAEKSSLSHPGIPPS 1509
A+ + + + + E++ N V+ G+ + A + G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 1510 PPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDN----LPASAWHSTD-------SASPQT 1558
P G P PS V + + + D+ +P + + + A P +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 1559 YEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLP-ALSMPRASRSLSKP 1617
+ Q +G +++K P + E+ S+E S + P A++ +A +L P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSES---SEESSDSADSEEAPAAMTAAQAKPALKIP 639
Query: 1618 EPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKT 1677
+ + CP+ +++T + G +++P+ T P +
Sbjct: 640 Q----TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS 695
Query: 1678 TPDIIKDWPRRKRAVGCGAGSSSGRG-EVGADLPGSLSLLESEGKDHGLELSIHRTPILE 1736
+ + + + AV G S G+G +V A S+ + S G+ L P +
Sbjct: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKA---ASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 1737 DFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLRED 1796
+ E + D E A+S Q S +K A A R +
Sbjct: 753 QVKAE---KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 1797 SEV----SKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPL 1852
+V +++K+ SPS + + + V G PS A+A QA T
Sbjct: 810 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP-- 864
Query: 1853 LFQGKTPSSQSKDPRDEDVDVL 1874
+ + SS+ + +E+ + L
Sbjct: 865 --EEDSGSSEEESDSEEEAETL 884
Score = 47.4 bits (111), Expect = 1e-04
Identities = 164/757 (21%), Positives = 256/757 (33%), Gaps = 131/757 (17%)
Query: 991 PGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDK 1050
P +G EE E E S S + + S ++ Q K S K
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-------SPAK 586
Query: 1051 SDQRENSPVQ-SIRSPKSLLFGAMSEMISPS----EKGSARMKKRSRNTLDSEVPAAYQT 1105
++ PV +++ K + SE S S E +A +++ L ++P
Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL--KIPQTKAC 644
Query: 1106 PKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
PKK++ + + +K P R+ T SPA +P + +DSSS
Sbjct: 645 PKKTN--TTASAKVAPVRVGTQAPRKAGTAT----SPAGSSPAVAGGTQRPAEDSSSSEE 698
Query: 1166 DSPLDSKITPQKRHTQAGE-GTSLETKTPRTPKR----QGTQPPGFLPNCTWPHSVN--- 1217
+ K QA G L+ K P + QGT P LP T P
Sbjct: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP--VLPGKTGPTVTQVKA 756
Query: 1218 ---SSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRA 1274
ES + + A P + + + + P AA + V A
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 1275 ARAEEPAQKLKDKAIKTPKRPGNSTVTS----SPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
A+A+ Q+ K + P NSTV + S P K + T+ + S+
Sbjct: 817 AQAK---QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 1331 ECPSPGE---LDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGK---R 1384
E S E L Q +P + P +P + P PP K G +
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK--------GAAPTPPGKTGPSAAQ 925
Query: 1385 CRKTSDPRRSIVECQPDASATPGVGTAD-------------SPAAPT------------- 1418
K D S E D A V +A SPA P
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1419 DSRDDQKGLSLSPQSPPERRGYPG-----PGLRSDWHASSPLLITSDTEHVTLLSEAEHH 1473
+R + S + P PG+R++ ++T T H + +A
Sbjct: 986 KARASESTARSSSSESEDEDVIPATQCLTPGIRTN-------VVTMPTAHPRIAPKASMA 1038
Query: 1474 GIGDLK--SNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDG 1531
G K S + ++ EG T ++K+ P S P ++ +
Sbjct: 1039 GASSSKESSRISDGKKQEGPATQVSKKN-------PASLPLTQAALKVLAQKASEAQPPV 1091
Query: 1532 RQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSK 1591
+ Q S+ +D SA + + SPQ+ V QA G KLR K+ P S
Sbjct: 1092 ARTQPSSGVD----SAVGTLPATSPQSTSV----QAKGTNKLRKPKLPEVQQATKAPESS 1143
Query: 1592 EESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHST-PGKSRGQTYICQACTPT 1650
++S E+S S S S E P + +H+ P SR +T + + +
Sbjct: 1144 DDS---EDS----------SDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAES 1190
Query: 1651 H-----GPS-STPSPFQTDGVPWTPSPKHSGKTTPDI 1681
PS S S + T G+ TP+ + K TP +
Sbjct: 1191 SEDDVVAPSQSLLSGYMTPGL--TPANSQASKATPKL 1225
Score = 42.0 bits (97), Expect = 0.006
Identities = 189/968 (19%), Positives = 326/968 (33%), Gaps = 137/968 (14%)
Query: 829 SSARRSVSGSPESDELQELRTRSAKKRR--KNALIRHKSIAEVSQNLRQIEIPKVSKRAT 886
SS V G P Q + + K + A + +V+ ++ +P +KRA
Sbjct: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP-AKRAK 264
Query: 887 KKENSHPAPQQPSQPVKD----TVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAV 942
K E + ++ S+ ++ T +V + L + +P+K G P + A
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAK-----GTPGKGATPAP 319
Query: 943 DGLEDKLDNFKK-------NKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDI 995
G + + K ++ + + S ETP +K LL + G++S G
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA----AKALLQAKASGKTSQVGAAS 375
Query: 996 GVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRE 1055
+ESP KG + P + ++ + SQ S ++SD E
Sbjct: 376 APAKESPRKG---AAPAPPGKTGPAVAKAQAGKREEDSQSSS-----------EESDSEE 421
Query: 1056 NSPVQSIRSPKSLLFGAMSEMISPS-EKGSARMKKRSRNTLDSEVPAAYQ------TPKK 1108
+P Q+ S K+ A S S KG+A R ++V Q + ++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
Query: 1109 SHQKSLSFSKTTPRRISHTPQTPLYTPERLQ-----------KSPAKMTPTKQAA----- 1152
S + + ++ ++P P P K+ P +A
Sbjct: 482 SDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW 541
Query: 1153 --FKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPG----- 1205
ES + SS D + + + P + + G L+ K +P + Q G
Sbjct: 542 EEDSESSSEESSDSSDGEVPTAVAPAQ---EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ 598
Query: 1206 -----FLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
+ N + S +S PA T++ A+P + P +T A+A +
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV-A 657
Query: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS 1320
P Q P +A A PA A T +RP + +S + ++ +
Sbjct: 658 PVRVGTQAPR--KAGTATSPAGSSPAVAGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQ 714
Query: 1321 KKSPFRKSKIEC---PSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDT---VP 1374
KS + +++ P G L Q + P V + E S+ + ++
Sbjct: 715 AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 1375 PPPPSKVGKRCRKTSDPRRSIVECQPDASATPGV-GTADSPAAPTDSRDDQKGLSLSPQS 1433
P++V +KT + P A+ P GT +P + K S S
Sbjct: 775 AASPAQVKTSVKKTQ------AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAE---HHGIGDLKSNVLSVEEGEG 1490
PP R L A P + S + V ++A+ G + S EE E
Sbjct: 829 PPVRNPQNSTVL-----ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 1491 L------------RTADAEKSSLSHPGIPPSPP-SCGPGSPLMPSRDVHCTTDGRQCQAS 1537
L R A A G P+PP GP + +D D
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD-----DSGSSSEE 938
Query: 1538 AQLDNLPASAWHSTDSASPQTYEVELEMQASG---LPKLRIKKIDPSSSLEAEPLSKEES 1594
+ D +A S P V+ +G P P + +E ++ S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
Query: 1595 SLGE-ESFLPALS-MPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHG 1652
S E E +PA + R+ PT P+ S + S+ + I G
Sbjct: 999 SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDG-KKQEG 1057
Query: 1653 PSSTPSPFQTDGVPWTPS-----PKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGA 1707
P++ S +P T + + + + P + + P +G S G + A
Sbjct: 1058 PATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQP--------SSGVDSAVGTLPA 1109
Query: 1708 DLPGSLSL 1715
P S S+
Sbjct: 1110 TSPQSTSV 1117
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 57.4 bits (137), Expect = 1e-07
Identities = 165/862 (19%), Positives = 294/862 (34%), Gaps = 74/862 (8%)
Query: 1032 VSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRS 1091
VS P S S S ++++++ + S S + GA S EK A +K
Sbjct: 78 VSDPISTSES---SEEEEEAEAETAKATPRLASTNSSVLGADLPS-SMKEKAKAETEKAG 133
Query: 1092 RNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKS-PAKMTPTKQ 1150
+ PA +T +L K+ + + T L + + S PA K
Sbjct: 134 KTGNSMPHPATGKTVA-----NLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP 188
Query: 1151 AAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNC 1210
DSSS S D K + + + T +P R+ PG + +
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV 248
Query: 1211 TWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPH 1270
T P+ PP +P E + + + A A GT ++Q
Sbjct: 249 T--------PQVKGGALPPAKRAKKPEEESESS-EEGSESEEEAPA--GT-RSQVKASEK 296
Query: 1271 VLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
+L+ A PA+ K TP PG + +S K S S S+
Sbjct: 297 ILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQTKAGKPEEDSE----SSSEESSDSEE 351
Query: 1331 ECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSD 1390
E P+ L Q + S + S P +P + P PP K G K
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRK--------GAAPAPPGKTGPAVAKAQA 403
Query: 1391 PRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWH 1450
+R + Q + + A + A P+ + S + P + P P ++
Sbjct: 404 GKRE-EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 1451 ASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEE-GEGLRTADAEKSSLSHPGIPPS 1509
A+ + + + + E++ N V+ G+ + A + G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 1510 PPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDN----LPASAWHSTD-------SASPQT 1558
P G P PS V + + + D+ +P + + + A P +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 1559 YEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLP-ALSMPRASRSLSKP 1617
+ Q +G +++K P + E+ S+E S + P A++ +A +L P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSES---SEESSDSADSEEAPAAMTAAQAKPALKIP 639
Query: 1618 EPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKT 1677
+ + CP+ +++T + G +++P+ T P +
Sbjct: 640 Q----TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS 695
Query: 1678 TPDIIKDWPRRKRAVGCGAGSSSGRG-EVGADLPGSLSLLESEGKDHGLELSIHRTPILE 1736
+ + + + AV G S G+G +V A S+ + S G+ L P +
Sbjct: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKA---ASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 1737 DFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLRED 1796
+ E + D E A+S Q S +K A A R +
Sbjct: 753 QVKAE---KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 1797 SEV----SKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPL 1852
+V +++K+ SPS + + + V G PS A+A QA T
Sbjct: 810 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP-- 864
Query: 1853 LFQGKTPSSQSKDPRDEDVDVL 1874
+ + SS+ + +E+ + L
Sbjct: 865 --EEDSGSSEEESDSEEEAETL 884
Score = 52.8 bits (125), Expect = 3e-06
Identities = 162/726 (22%), Positives = 253/726 (34%), Gaps = 107/726 (14%)
Query: 991 PGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDK 1050
P +G EE E E S S + + S ++ Q K S K
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-------SPAK 586
Query: 1051 SDQRENSPVQ-SIRSPKSLLFGAMSEMISPS----EKGSARMKKRSRNTLDSEVPAAYQT 1105
++ PV +++ K + SE S S E +A +++ L ++P
Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL--KIPQTKAC 644
Query: 1106 PKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGH 1165
PKK++ + + +K P R+ T SPA +P + +DSSS
Sbjct: 645 PKKTN--TTASAKVAPVRVGTQAPRKAGTAT----SPAGSSPAVAGGTQRPAEDSSSSEE 698
Query: 1166 DSPLDSKITPQKRHTQAGE-GTSLETKTPRTPKR----QGTQPPGFLPNCTWPHSVN--- 1217
+ K QA G L+ K P + QGT P LP T P
Sbjct: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP--VLPGKTGPTVTQVKA 756
Query: 1218 ---SSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRA 1274
ES + + A P + + + + P AA + V A
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 1275 ARAEEPAQKLKDKAIKTPKRPGNSTVTS----SPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
A+A+ Q+ K + P NSTV + S P K + T+ + S+
Sbjct: 817 AQAK---QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 1331 ECPSPGE---LDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGK---R 1384
E S E L Q +P + P +P + P PP K G +
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK--------GAAPTPPGKTGPSAAQ 925
Query: 1385 CRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPG 1444
K D S E D A V +A P D + + +P + + P
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1445 -LRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSH 1503
R+ + S+ E V ++ GI ++NV+++ +H
Sbjct: 986 KARASESTARSSSSESEDEDVIPATQCLTPGI---RTNVVTMPT--------------AH 1028
Query: 1504 PGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASA-QLDNLPASAWHSTDSASPQTYEVE 1562
P I P G S SR +DG++ + A Q+D SA + + SPQ+ V
Sbjct: 1029 PRIAPKASMAGASSSKESSR----ISDGKKQEGPATQVD----SAVGTLPATSPQSTSV- 1079
Query: 1563 LEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYV 1622
QA G KLR K+ P S ++S E+S S S S E
Sbjct: 1080 ---QAKGTNKLRKPKLPEVQQATKAPESSDDS---EDS----------SDSSSGSEEDGE 1123
Query: 1623 SPPCPRLSHST-PGKSRGQTYICQACTPTH-----GPS-STPSPFQTDGVPWTPSPKHSG 1675
P + +H+ P SR +T + + + PS S S + T G+ TP+ +
Sbjct: 1124 GPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGL--TPANSQAS 1181
Query: 1676 KTTPDI 1681
K TP +
Sbjct: 1182 KATPKL 1187
Score = 40.8 bits (94), Expect = 0.013
Identities = 168/851 (19%), Positives = 287/851 (33%), Gaps = 122/851 (14%)
Query: 829 SSARRSVSGSPESDELQELRTRSAKKRR--KNALIRHKSIAEVSQNLRQIEIPKVSKRAT 886
SS V G P Q + + K + A + +V+ ++ +P +KRA
Sbjct: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP-AKRAK 264
Query: 887 KKENSHPAPQQPSQPVKD----TVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAV 942
K E + ++ S+ ++ T +V + L + +P+K G P + A
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAK-----GTPGKGATPAP 319
Query: 943 DGLEDKLDNFKK-------NKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDI 995
G + + K ++ + + S ETP +K LL + G++S G
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA----AKALLQAKASGKTSQVGAAS 375
Query: 996 GVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRE 1055
+ESP KG + P + ++ + SQ S ++SD E
Sbjct: 376 APAKESPRKG---AAPAPPGKTGPAVAKAQAGKREEDSQSSS-----------EESDSEE 421
Query: 1056 NSPVQSIRSPKSLLFGAMSEMISPS-EKGSARMKKRSRNTLDSEVPAAYQ------TPKK 1108
+P Q+ S K+ A S S KG+A R ++V Q + ++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
Query: 1109 SHQKSLSFSKTTPRRISHTPQTPLYTPERLQ-----------KSPAKMTPTKQAA----- 1152
S + + ++ ++P P P K+ P +A
Sbjct: 482 SDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW 541
Query: 1153 --FKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPG----- 1205
ES + SS D + + + P + + G L+ K +P + Q G
Sbjct: 542 EEDSESSSEESSDSSDGEVPTAVAPAQ---EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ 598
Query: 1206 -----FLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
+ N + S +S PA T++ A+P + P +T A+A +
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV-A 657
Query: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS 1320
P Q P +A A PA A T +RP + +S + ++ +
Sbjct: 658 PVRVGTQAPR--KAGTATSPAGSSPAVAGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQ 714
Query: 1321 KKSPFRKSKIEC---PSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDT---VP 1374
KS + +++ P G L Q + P V + E S+ + ++
Sbjct: 715 AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 1375 PPPPSKVGKRCRKTSDPRRSIVECQPDASATPGV-GTADSPAAPTDSRDDQKGLSLSPQS 1433
P++V +KT + P A+ P GT +P + K S S
Sbjct: 775 AASPAQVKTSVKKTQ------AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAE---HHGIGDLKSNVLSVEEGEG 1490
PP R L A P + S + V ++A+ G + S EE E
Sbjct: 829 PPVRNPQNSTVL-----ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 1491 L------------RTADAEKSSLSHPGIPPSPP-SCGPGSPLMPSRDVHCTTDGRQCQAS 1537
L R A A G P+PP GP + +D D
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD-----DSGSSSEE 938
Query: 1538 AQLDNLPASAWHSTDSASPQTYEVELEMQASG---LPKLRIKKIDPSSSLEAEPLSKEES 1594
+ D +A S P V+ +G P P + +E ++ S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
Query: 1595 SLGE-ESFLPA 1604
S E E +PA
Sbjct: 999 SESEDEDVIPA 1009
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 57.4 bits (137), Expect = 1e-07
Identities = 165/862 (19%), Positives = 294/862 (34%), Gaps = 74/862 (8%)
Query: 1032 VSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRS 1091
VS P S S S ++++++ + S S + GA S EK A +K
Sbjct: 78 VSDPISTSES---SEEEEEAEAETAKATPRLASTNSSVLGADLPS-SMKEKAKAETEKAG 133
Query: 1092 RNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKS-PAKMTPTKQ 1150
+ PA +T +L K+ + + T L + + S PA K
Sbjct: 134 KTGNSMPHPATGKTVA-----NLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP 188
Query: 1151 AAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNC 1210
DSSS S D K + + + T +P R+ PG + +
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDV 248
Query: 1211 TWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPH 1270
T P+ PP +P E + + + A A GT ++Q
Sbjct: 249 T--------PQVKGGALPPAKRAKKPEEESESS-EEGSESEEEAPA--GT-RSQVKASEK 296
Query: 1271 VLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKI 1330
+L+ A PA+ K TP PG + +S K S S S+
Sbjct: 297 ILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQTKAGKPEEDSE----SSSEESSDSEE 351
Query: 1331 ECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSD 1390
E P+ L Q + S + S P +P + P PP K G K
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRK--------GAAPAPPGKTGPAVAKAQA 403
Query: 1391 PRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWH 1450
+R + Q + + A + A P+ + S + P + P P ++
Sbjct: 404 GKRE-EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 1451 ASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEE-GEGLRTADAEKSSLSHPGIPPS 1509
A+ + + + + E++ N V+ G+ + A + G
Sbjct: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Query: 1510 PPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDN----LPASAWHSTD-------SASPQT 1558
P G P PS V + + + D+ +P + + + A P +
Sbjct: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 1559 YEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLP-ALSMPRASRSLSKP 1617
+ Q +G +++K P + E+ S+E S + P A++ +A +L P
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSES---SEESSDSADSEEAPAAMTAAQAKPALKIP 639
Query: 1618 EPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKT 1677
+ + CP+ +++T + G +++P+ T P +
Sbjct: 640 Q----TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS 695
Query: 1678 TPDIIKDWPRRKRAVGCGAGSSSGRG-EVGADLPGSLSLLESEGKDHGLELSIHRTPILE 1736
+ + + + AV G S G+G +V A S+ + S G+ L P +
Sbjct: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKA---ASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 1737 DFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLRED 1796
+ E + D E A+S Q S +K A A R +
Sbjct: 753 QVKAE---KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 1797 SEV----SKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPL 1852
+V +++K+ SPS + + + V G PS A+A QA T
Sbjct: 810 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP-- 864
Query: 1853 LFQGKTPSSQSKDPRDEDVDVL 1874
+ + SS+ + +E+ + L
Sbjct: 865 --EEDSGSSEEESDSEEEAETL 884
Score = 41.2 bits (95), Expect = 0.010
Identities = 158/798 (19%), Positives = 271/798 (33%), Gaps = 117/798 (14%)
Query: 829 SSARRSVSGSPESDELQELRTRSAKKRR--KNALIRHKSIAEVSQNLRQIEIPKVSKRAT 886
SS V G P Q + + K + A + +V+ ++ +P +KRA
Sbjct: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP-AKRAK 264
Query: 887 KKENSHPAPQQPSQPVKD----TVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAV 942
K E + ++ S+ ++ T +V + L + +P+K G P + A
Sbjct: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAK-----GTPGKGATPAP 319
Query: 943 DGLEDKLDNFKK-------NKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDI 995
G + + K ++ + + S ETP +K LL + G++S G
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA----AKALLQAKASGKTSQVGAAS 375
Query: 996 GVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRE 1055
+ESP KG + P + ++ + SQ S ++SD E
Sbjct: 376 APAKESPRKG---AAPAPPGKTGPAVAKAQAGKREEDSQSSS-----------EESDSEE 421
Query: 1056 NSPVQSIRSPKSLLFGAMSEMISPS-EKGSARMKKRSRNTLDSEVPAAYQ------TPKK 1108
+P Q+ S K+ A S S KG+A R ++V Q + ++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE 481
Query: 1109 SHQKSLSFSKTTPRRISHTPQTPLYTPERLQ-----------KSPAKMTPTKQAA----- 1152
S + + ++ ++P P P K+ P +A
Sbjct: 482 SDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW 541
Query: 1153 --FKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPG----- 1205
ES + SS D + + + P + + G L+ K +P + Q G
Sbjct: 542 EEDSESSSEESSDSSDGEVPTAVAPAQ---EKSLGNILQAKPTSSPAKGPPQKAGPVAVQ 598
Query: 1206 -----FLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
+ N + S +S PA T++ A+P + P +T A+A +
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV-A 657
Query: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVS 1320
P Q P +A A PA A T +RP + +S + ++ +
Sbjct: 658 PVRVGTQAPR--KAGTATSPAGSSPAVAGGT-QRPAEDSSSSEESDSEEEKTGLAVTVGQ 714
Query: 1321 KKSPFRKSKIEC---PSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDT---VP 1374
KS + +++ P G L Q + P V + E S+ + ++
Sbjct: 715 AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 1375 PPPPSKVGKRCRKTSDPRRSIVECQPDASATPGV-GTADSPAAPTDSRDDQKGLSLSPQS 1433
P++V +KT + P A+ P GT +P + K S S
Sbjct: 775 AASPAQVKTSVKKTQ------AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAE---HHGIGDLKSNVLSVEEGEG 1490
PP R L A P + S + V ++A+ G + S EE E
Sbjct: 829 PPVRNPQNSTVL-----ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 883
Query: 1491 L------------RTADAEKSSLSHPGIPPSPP-SCGPGSPLMPSRDVHCTTDGRQCQAS 1537
L R A A G P+PP GP + +D G + S
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD----DSGSSSEES 939
Query: 1538 AQLDNLPASAWHSTDSAS 1555
PA+ + D S
Sbjct: 940 DSDGEAPAAVTSAQDQES 957
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 57.0 bits (136), Expect = 2e-07
Identities = 185/939 (19%), Positives = 325/939 (34%), Gaps = 151/939 (16%)
Query: 797 PQKLAGVLPTDFFS-----DDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQELRTRS 851
P+K+ T + + + T+++++ + S L+ +++ + ++EL +
Sbjct: 226 PEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEP 285
Query: 852 AKKRRKNALIRHK-SIAEVSQNLRQIEI---------PKVSKRATKKENSHPAPQQPSQP 901
+ + A + S AE ++N + P ++ T EN+ P P P++
Sbjct: 286 TEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTEN 345
Query: 902 VKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNKGYHKL 961
+ T E T LF E +R+ S + G +N
Sbjct: 346 REMTANENT----TLFPAEPTEHGERTANENTTPSPAEPTEHGERTANEN---------- 391
Query: 962 LTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISL---RRSPRIKQ 1018
T S AE H +R K SS ES E G+ L +P +
Sbjct: 392 TTPSPAEPTEH---GERTPFANDKTTSSS--------AESTEHGERTPLANENTTPSPAE 440
Query: 1019 LSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMIS 1078
+ +R +A+ + P + R + +++ SPV+ + ++ +E +
Sbjct: 441 PTENRERTANENTTPSPAGPTENR----ETTANEKTTLSPVEPTENRET----TANEKTT 492
Query: 1079 PSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERL 1138
PS +R+ + ++ + + + L+ TTP T E+
Sbjct: 493 PSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKT 552
Query: 1139 QKSPAK------MTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKT 1192
SPA+ TP SL + + G +P + +K + + E T E +T
Sbjct: 553 TPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFAN----EKTTSSSAEPTEHEERT 608
Query: 1193 PRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLT-----PIRDP 1247
P + P N + N++P PA PT + E T P +
Sbjct: 609 PLANENTTPSPAEPTENRERTANENTTPS----PAGPTENREMTANEKTTLFPAEPTENR 664
Query: 1248 LRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVT 1307
RT + Q+ A+ + +TP N+T++ + P
Sbjct: 665 ERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEP-TEHGERTPLANENTTLSPAEPTE 723
Query: 1308 PKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQR 1367
++ + K +PF P E + + A + P P+ P E R
Sbjct: 724 NRERTAN-----EKTTPF---------PAEPTENRER----TANENTTPSPAQPTENGDR 765
Query: 1368 ATLDTVPPPP----PSKVGKRCRKTSD-PRRSIVECQPDASATP--GVGTADSPAAPTDS 1420
L P P++ GKR ++ S E A TP T SPA PT++
Sbjct: 766 TPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTEN 825
Query: 1421 RD--DQKGLSLSPQSPPERR---------GYPG-PGLRSDWHASSPLLITSDTEHVTL-- 1466
R+ + + P P E R +P P +W A+ E+ TL
Sbjct: 826 RERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTAN---------ENTTLSP 876
Query: 1467 LSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPS---PPSCGPGSPLMPSR 1523
EH + L + ++ E T + E++ ++ PS P G +PL +
Sbjct: 877 AEPTEHEEMTPLANEKTTLSPAE--PTENGERTPFTNEKTTPSSAEPTEHGERTPL--AN 932
Query: 1524 DVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSS 1583
++ + + ++ N A T S + T E + P +P+ +
Sbjct: 933 EITTPSRAEPTEHGERIANEKA-----TPSPAKPTEHGETTVNEDTTP----SSAEPTEN 983
Query: 1584 LEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYI 1643
E PL+ E ++ P S R+ + E T SP P H S + I
Sbjct: 984 GERTPLANENTTTS-----PTESTEHGERTAN--EKTTPSPAEP-TEHGERTPSANEKTI 1035
Query: 1644 CQACTPTHGPSSTPSPFQTDGVPWTPSP----KHSGKTT 1678
PT TPS + TPSP +H KTT
Sbjct: 1036 PSPAKPTEHEEMTPSANENT----TPSPVKPTEHGEKTT 1070
Score = 48.5 bits (114), Expect = 6e-05
Identities = 107/551 (19%), Positives = 191/551 (34%), Gaps = 63/551 (11%)
Query: 879 PKVSKRATKKENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHS 938
P ++ T E + P P +P++ + T E T SP++ + +
Sbjct: 721 PTENRERTANEKTTPFPAEPTENRERTANENTTP----------SPAQPTENGDRTPLAN 770
Query: 939 VSAVDGLEDKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVV 998
L + +N K+ ++ T S AE H ++R SS P
Sbjct: 771 EKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEH---AERTPLANENTTSSPAEPTENRE 827
Query: 999 EESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSP 1058
+ EK + + + + +T + ++R + ++ E+
Sbjct: 828 RTANEKTTQFPAEPTENRESTANEKTTP---FPAEPTENREWTANENTTLSPAEPTEHEE 884
Query: 1059 VQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSK 1118
+ + + K+ L A P+E G +R+ T + P++ + + + L+
Sbjct: 885 MTPLANEKTTLSPA-----EPTENG-----ERTPFTNEKTTPSSAEPTEHGERTPLANEI 934
Query: 1119 TTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSP----GHDSPL--DSK 1172
TTP R T E+ SPAK T + E SS+ G +PL ++
Sbjct: 935 TTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENT 994
Query: 1173 ITPQKRHTQAGEGTSLE--TKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPT 1230
T T+ GE T+ E T +P P G + P T P + P+
Sbjct: 995 TTSPTESTEHGERTANEKTTPSPAEPTEHGERTPS-ANEKTIPSPAKPTEHEEMTPSANE 1053
Query: 1231 SSTAQPRR-----ECLTPIRDPLRTPPRAAAFMGTPQNQTHQQ--PHVLR----AARAEE 1279
++T P + E T + + P G +++ P + + R
Sbjct: 1054 NTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTS 1113
Query: 1280 PAQKLKDKAIKTPK---RPGNSTVTSSPPVTPKK------LFTSPLCDVSKKSPFRKSKI 1330
P K+ A ++ + R ++ V + P P K L + V++KS K
Sbjct: 1114 PNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEK- 1172
Query: 1331 ECPSPGELDQKEPQMSPSVAASLSC------PVPSTPPELSQRATLDTVPPPPPSKVGKR 1384
S E + P+ + C PVP P E TL T P K +
Sbjct: 1173 -TTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTEN 1231
Query: 1385 CRKTSDPRRSI 1395
KT+ ++I
Sbjct: 1232 PEKTAAVTKTI 1242
Score = 46.6 bits (109), Expect = 2e-04
Identities = 129/670 (19%), Positives = 224/670 (33%), Gaps = 71/670 (10%)
Query: 879 PKVSKRATKKENSHPAPQQPSQPVKDTVQEVTKVR--RNLFNQELLSPSKRSLKRGLPRS 936
P ++ T EN+ P+P P++ + T E T + N+E + K + P
Sbjct: 441 PTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTE 500
Query: 937 HSVSAVDGLEDKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIG 996
+ +K + H T E + + P P
Sbjct: 501 NG-QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSP--- 556
Query: 997 VVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQREN 1056
E E GD L L+ T + + K+ S + ++++
Sbjct: 557 --AEPTENGDRTPLANEKTTPSLA-EPTENGQRTPFANEKTTSSSAEPTEHEERTPLANE 613
Query: 1057 SPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSF 1116
+ S P +E +PS G ++ + N + PA P ++ +++ +
Sbjct: 614 NTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPA---EPTENRERTANE 670
Query: 1117 SKT-TPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSP-----GHDSPLD 1170
T +P + Q + E+ S A+ T + + + SP + +
Sbjct: 671 KTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTAN 730
Query: 1171 SKITP------QKRHTQAGEGTSLETKTPRTPKRQGTQPP----GFLPNCTWPHSVNSSP 1220
K TP + R A E T T +P P G + P P+ P +
Sbjct: 731 EKTTPFPAEPTENRERTANENT---TPSPAQPTENGDRTPLANEKTTPSLAEP--TENGK 785
Query: 1221 ESPSCPAPPTSSTAQPRREC-LTPIRDPLRTPPRAAAFMG---TPQNQTHQ---QPHVLR 1273
+P TSS+A+P TP+ + T A T +T Q +P R
Sbjct: 786 RTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENR 845
Query: 1274 AARAEEPAQKLKDKAIKTPKRPGNSTVTSSP----------PVTPKKLFTSPL--CDVSK 1321
+ A E + + + N T SP P+ +K SP + +
Sbjct: 846 ESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGE 905
Query: 1322 KSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPP--PS 1379
++PF K +P + E +A ++ P + P E +R + P P P+
Sbjct: 906 RTPFTNEK---TTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPT 962
Query: 1380 KVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSP----P 1435
+ G+ D S E + TP + ++ +PT+S + + + +P P
Sbjct: 963 EHGE-TTVNEDTTPSSAEPTENGERTP-LANENTTTSPTESTEHGERTANEKTTPSPAEP 1020
Query: 1436 ERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTAD 1495
G P S TEH + A + S V E GE A+
Sbjct: 1021 TEHGERTPSANEKTIPSP----AKPTEHEEMTPSANEN---TTPSPVKPTEHGEKTTLAN 1073
Query: 1496 AEKSSLSHPG 1505
EK +LS G
Sbjct: 1074 -EKITLSPEG 1082
Score = 35.0 bits (79), Expect = 0.70
Identities = 102/488 (20%), Positives = 163/488 (33%), Gaps = 72/488 (14%)
Query: 1227 APPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKD 1286
APPTS + IR+ P + T ++ + H+ PA K K
Sbjct: 117 APPTSEENSSNQGKDPMIRNQRSVDPADST---TTHKESAGKKHIT-------PAPKSKI 166
Query: 1287 KAIKTPKRPGNSTVTSSPPVT--PKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQ 1344
K+ G STVT T P + S L S S + + QK
Sbjct: 167 NCRKSTT--GKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS 224
Query: 1345 MSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKT-------SDPRRSIVE 1397
+ A+ +T T D+ K+ + K ++ +S+ E
Sbjct: 225 FPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAE 284
Query: 1398 CQPDASATPGVGTADSPAAPTDSRD--DQKGLSLSPQSPPERRGYPGPGLRSDWHA--SS 1453
T SPA PT++R+ + +LSP P E R + + A +
Sbjct: 285 PTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTE 344
Query: 1454 PLLITSDTEHVTLLSEAEHHGIGDLKSNVL-----SVEEGEGLRTADAEKSSLSHPGIPP 1508
+T++ +E HG N E GE RTA+ E ++ S P
Sbjct: 345 NREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGE--RTAN-ENTTPS----PA 397
Query: 1509 SPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQAS 1568
P G +P + T +++ + P + ++T S + T E +
Sbjct: 398 EPTEHGERTPFANDK-----TTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANEN 452
Query: 1569 GLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPR 1628
P A P E++ E++ L + P +R + E T SP P
Sbjct: 453 TTPS------------PAGPTENRETTANEKTTLSPVE-PTENRETTANEKTTPSPAEPT 499
Query: 1629 LSHSTPGKSRGQTYICQACTPTHG-------PSSTPSPFQ-------TDGVPWTPS---P 1671
+ + +T A HG ++TPSP + T TPS P
Sbjct: 500 ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEP 559
Query: 1672 KHSGKTTP 1679
+G TP
Sbjct: 560 TENGDRTP 567
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 55.8 bits (133), Expect = 4e-07
Identities = 155/707 (21%), Positives = 240/707 (33%), Gaps = 112/707 (15%)
Query: 783 KTLGNLYNSLGFVIPQKLAGVLPTDFFS--DDSMTQENKSPLLSVPFLSSARRSVSGSP- 839
++ G ++L P +G PT S +DS + ++ L R S P
Sbjct: 974 RSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPL 1033
Query: 840 -----ESDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPA 894
+S E +ELR R + + R + R+ K RA ++
Sbjct: 1034 LPTIEDSSEEEELREEEELLREQEKM-REVEQQRIRSTARKTRRDKEELRAQRRRERSKT 1092
Query: 895 PQQPSQPVKDT--------VQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLE 946
P P++D E+ ++ R+ ++ SPS S L S G E
Sbjct: 1093 PPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSE 1152
Query: 947 DKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGD 1006
L F + S ETP S P G +S E+
Sbjct: 1153 YNLPTF--------MSLYSPTETP----------------SGSSTTPSSGRPLKSAEEAY 1188
Query: 1007 EISLRRSPRIKQLSFSRTHSASFYS-VSQPKSRSVQRVHSFQ-QDKSDQRENSPVQ-SIR 1063
E +R++ +++ + + SQP + + SF+ QD +D+ Q +
Sbjct: 1189 EEMMRKAELLQRQQGQAAGARGPHGGPSQPTGP--RGLGSFEYQDTTDREYGQAAQPAAE 1246
Query: 1064 SPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKT--TP 1121
+ L A+ E I + + RM++ S L A+ KK ++ L+ P
Sbjct: 1247 GTPASLGAAVYEEILQTSQSIVRMRQASSRDL------AFAEDKKKEKQFLNAESAYMDP 1300
Query: 1122 RRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKIT------- 1174
+ + P TP +P +L + TPT SS G P D ++T
Sbjct: 1301 MKQNGGPLTPGTSPTQLAAPVSFSTPTSS---------DSSGGRVIP-DVRVTQHFAKET 1350
Query: 1175 --PQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPA----- 1227
P K H+ +S +K P QG P P + +P+ PA
Sbjct: 1351 QDPLKLHSSPASPSSA-SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERS 1409
Query: 1228 PPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVL----RAARAEEPAQK 1283
P SSTA T A G+ Q P L RAAR + +
Sbjct: 1410 PSPSSTAHSYGHSPT------------TANYGSQTEDLPQAPSGLAAAGRAAREKPLSAS 1457
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKI--ECPSPGELDQK 1341
+ P R + +SSPP++P SP K P ++ + PSP
Sbjct: 1458 DGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDM 1517
Query: 1342 -----EPQMSPSVAASLSCP-VPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSI 1395
P SP VA P PSTP + Q ++ + P V S R +
Sbjct: 1518 PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEA-----PFMVITLASDASSQTRMV 1572
Query: 1396 VECQPDASATPGVG-TADSPAAPTDSRDDQKGLSLSPQSPPERRGYP 1441
AS +P T P S+ +S P PP G+P
Sbjct: 1573 ---HASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFP 1616
Score = 36.6 bits (83), Expect = 0.24
Identities = 57/247 (23%), Positives = 90/247 (36%), Gaps = 27/247 (10%)
Query: 1115 SFSKTTPRRISHTPQTPLYTPERLQ-KSPAKMTPTK---QAAFKESLKDSSSPGHDSPLD 1170
S + TP + Q P+ P R SP K + Q + K S SPL
Sbjct: 524 SLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLP 583
Query: 1171 SKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPT 1230
SK +PQ + +A E +KTP + + + T+ P P PE+ PA P
Sbjct: 584 SKASPQAKPLRASE----PSKTPSSVQEKKTRVPTKAEPMPKP-----PPETTPTPATPK 634
Query: 1231 SSTAQPRRECLTPIRDPLRTPPR---AAAFMGTPQNQ-THQQPHVLRAARAEEPAQKLKD 1286
+ R E TP+ + P+ A +G P +Q + P L
Sbjct: 635 VKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQ 694
Query: 1287 KAI-----KTPKRPGNSTVTSSPPVTPKKLF-----TSPLCDVSKKSPFRKSKIECPSPG 1336
I + ++ ++ VT P +P ++ PL +P +SK G
Sbjct: 695 SEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTG 754
Query: 1337 ELDQKEP 1343
E ++ P
Sbjct: 755 EEQKQRP 761
Score = 35.0 bits (79), Expect = 0.70
Identities = 36/149 (24%), Positives = 57/149 (38%), Gaps = 20/149 (13%)
Query: 1309 KKLFTSPLCDVSKKSPFRKSKIE----CPSPGELDQKEPQMSPSVAASLSCPVPSTPPEL 1364
++ + P SK P + +++ P P + + PS AAS P+
Sbjct: 3726 RQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQ-------PQT 3778
Query: 1365 SQRATLDTVPPPPPSKVGKRCRKTSDPRR---SIVECQPDASATPGVGTADSPAAPTDSR 1421
Q+ + PP + R ++ S P + QP PG TA P R
Sbjct: 3779 QQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPR 3838
Query: 1422 DDQ----KGLSLSPQS--PPERRGYPGPG 1444
+Q KG + +PQ P+ + PGPG
Sbjct: 3839 AEQTNGSKGTAKAPQQGRAPQAQPAPGPG 3867
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 55.5 bits (132), Expect = 5e-07
Identities = 103/432 (23%), Positives = 152/432 (35%), Gaps = 57/432 (13%)
Query: 1019 LSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMIS 1078
LS S S S S S P+S+S HS Q D S + P +RS +S + S
Sbjct: 529 LSSSSIKSGSSSS-SIPESQSN---HSNQSD-SGVSDTQPAGHVRSQS-----IVSSVFS 578
Query: 1079 PSEKGSARMKKRSRNTLDS-EVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPER 1137
+ K ++++ S+ ++S P P S Q + TP S P PL P
Sbjct: 579 EAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKI----VTPYTASQ-PSPPLPPPPP 633
Query: 1138 LQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGE--GTSLETKTPRT 1195
P P + + S G +P+ K + R A + G + TP
Sbjct: 634 PPPPPPPPPPPPPPPLPS--QSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPV 691
Query: 1196 PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAA 1255
+ Q +P +P P+ V P P P P S+ AQ + P PP
Sbjct: 692 MQSQSVKPQILVP----PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP--- 744
Query: 1256 AFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSP 1315
P + HQ H+ + A TP P P PK L T P
Sbjct: 745 -----PPLKIHQVQHITQVAPP-------------TPPPPPPIPAPLPPQAPPKPLVTIP 786
Query: 1316 LCDVSKKSPFRKSKIECPSPGEL---DQKEPQMSPSVA--ASLSCPVPSTPPELSQRATL 1370
+K ++ P+P +K+P S + + PVP PP L ++ +
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846
Query: 1371 DTVPPPPP-SKVGKRCRKTSD-----PRRSIVECQPDASATPGVGTADSPAAPTDSRDDQ 1424
PPP P S V ++ + P +E QP V PA +
Sbjct: 847 CAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP 906
Query: 1425 KGLSL-SPQSPP 1435
+ + SP PP
Sbjct: 907 SSIPVPSPDFPP 918
Score = 41.6 bits (96), Expect = 0.007
Identities = 86/337 (25%), Positives = 115/337 (34%), Gaps = 77/337 (22%)
Query: 1100 PAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKD 1159
P A TP KS SKT+ S + P TP+R S+K
Sbjct: 944 PTASPTPDKSGSPGKKTSKTS----SPGGKKPPPTPQR----------------NSSIKS 983
Query: 1160 SSSPGHDSP-------LDSKITPQKRHTQAGEGTSLETKTPRTPKR---QGTQPPGFLPN 1209
SS H P L SK TP + T P P + G PG L
Sbjct: 984 SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQ 1043
Query: 1210 -CTWPHSV-------NSSPESPSCPA-----PPTSSTAQPRRECLTPIRDPL----RTPP 1252
C + +S E PS P+ PP T P L PI P T P
Sbjct: 1044 GCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP----LPPIEIPAVFSGNTSP 1099
Query: 1253 RAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTP--KRPGNSTVTSSPPVTPKK 1310
+ A PQ Q + V +A P + + + ++P +TV P +PK
Sbjct: 1100 KVAVV--NPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKS 1157
Query: 1311 -LFTSP--LCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPEL--- 1364
L P L D+++ RKS G L + + P+ +P PPEL
Sbjct: 1158 SLSVQPGFLADLNRTLQ-RKS---ITRHGSLSSRMSRAEPTATMD-DMALPPPPPELLSD 1212
Query: 1365 -----------SQRATLDTVPPPPPSKVGKRCRKTSD 1390
S ATL PPP P K + + + D
Sbjct: 1213 QQKAGYGGSHISGYATLRRGPPPAPPKRDQNTKLSRD 1249
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 55.5 bits (132), Expect = 5e-07
Identities = 137/588 (23%), Positives = 205/588 (34%), Gaps = 101/588 (17%)
Query: 1002 PEKGDEISLRRSPRIKQLSFSRTHSAS---------FYSVSQPKSRSVQRVHSFQQDKSD 1052
P D ++L R ++ LS HSAS F SVS P+ RS + S S
Sbjct: 361 PPTVDVVALGRCS-LRTLSRCSLHSASPASVRSLGRFSSVSSPQPRS-RHPSSSSDTWSH 418
Query: 1053 QRENSPVQSIRSPKSLLFG---------AMSEMISPSEKGSARMKKRSRNTLDSEVPAAY 1103
+ + + S S S G A + ++ P + GS R +T ++ +
Sbjct: 419 SQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSI 478
Query: 1104 QTPKKSHQKSLSFSKTT----PRRISHT--------PQTPLYTP---ERLQKSPAKMTPT 1148
++ + +S+S K P R +H+ P PL P ER Q+ PT
Sbjct: 479 RSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPT 538
Query: 1149 K-------QAAFKESLKDSSSPGHDSPLDSKITPQ--KRHTQAGEGTSLETKTPRTPKRQ 1199
A + +S PG SP S+ P+ +R G S ++ TP P +
Sbjct: 539 TGGSEGAGAAPCPPNPANSWVPGL-SPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKG 597
Query: 1200 GTQPPGF----------------LPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTP 1243
PP P + S+ S S S PAP S Q LTP
Sbjct: 598 LAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ----ILTP 653
Query: 1244 IRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSS 1303
+ D PP + P + +P R+ PA P + +
Sbjct: 654 LGDRFVIPPHPK--VPAPFSPPPSKP------RSPNPAAPALAAPAVVPGPVSTTDASPQ 705
Query: 1304 PPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPE 1363
P TP+ T PL ++SP SK + P P P P+ + PS
Sbjct: 706 SPPTPQTTLT-PL----QESPVI-SKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASET 759
Query: 1364 LSQRATLDTVPPPPPSKVGKRCRKTSD---PRRSIVECQPDASATPGVGTADSPAAPTDS 1420
+ PPPPP ++ +D P + A P G+ + ++P S
Sbjct: 760 AEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPS-GSPELVSSPAAS 818
Query: 1421 RDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKS 1480
L + P P+ P P +P +S HV L + E +G K
Sbjct: 819 SSSATALQIQPPGSPD----PPPA------PPAPAPASSAPGHVAKLPQKE--PVGCSKG 866
Query: 1481 NVLSVEE-GEGLRTAD----AEKSSLSHPGIPPSPPSCGPGSPLMPSR 1523
E+ G L T S+ PG P+ P+ GP +P P R
Sbjct: 867 GGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT-PALGPSAPQKPLR 913
Score = 44.3 bits (103), Expect = 0.001
Identities = 52/218 (23%), Positives = 79/218 (36%), Gaps = 17/218 (7%)
Query: 1492 RTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHST 1551
R+ + +L+ P + P P S SP P T ++ ++ + P S S
Sbjct: 678 RSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSY 737
Query: 1552 DSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRAS 1611
P T + E+ ++A + + + + P + EE L F P A
Sbjct: 738 HPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP---EEAF 794
Query: 1612 RSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSP 1671
S++ PEP S P L S S T + P P P+P P + +P
Sbjct: 795 FSVASPEPAGPS-GSPELVSSPAASSSSATAL--QIQPPGSPDPPPAP--PAPAPASSAP 849
Query: 1672 KHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADL 1709
H K +K VGC G R +VGA L
Sbjct: 850 GHVAKLP---------QKEPVGCSKGGGPPREDVGAPL 878
Score = 32.7 bits (73), Expect = 3.5
Identities = 50/226 (22%), Positives = 75/226 (33%), Gaps = 30/226 (13%)
Query: 1160 SSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNS- 1218
SS+PGH + L PQK +G P R+ P P+ + S
Sbjct: 846 SSAPGHVAKL-----PQKEPVGCSKGGG--------PPREDVGAPLVTPSLLQMVRLRSV 892
Query: 1219 -SPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRA--------AAFMGTPQNQTHQQP 1269
+P PA S+ +P R L+ P+ P A + + + QP
Sbjct: 893 GAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQP 952
Query: 1270 HVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSK 1329
+ A P + K G+ + PV+P+ D+ +
Sbjct: 953 NGPPEAEPRPPQSPASTASFIFSK--GSRKLQLERPVSPETQ-----ADLQRNLVAELRS 1005
Query: 1330 IECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPP 1375
I P + +K P+ P VA S VP RA T PP
Sbjct: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPP 1051
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 55.1 bits (131), Expect = 7e-07
Identities = 95/393 (24%), Positives = 137/393 (34%), Gaps = 50/393 (12%)
Query: 1151 AAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQP---PGFL 1207
A +E L P S L + + R + T E P P R P PG
Sbjct: 1059 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG-- 1116
Query: 1208 PNCTWPHSVNSSPESPSCPAP-PTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTH 1266
P S SSP P P AQP L P R P PPR A P
Sbjct: 1117 -----PPSAQSSPIDAQPATPLPQKDPAQP----LEPKRPP---PPRPVAPPTRPAPP-- 1162
Query: 1267 QQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFR 1326
Q+P AR+ P +K + I P PG V PK T+ ++ + P
Sbjct: 1163 QRPPPPSGARSPAPTRK-EFGGIGAPPSPG---VARREMEAPKSPGTTRKDNIGRSQPSP 1218
Query: 1327 KSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCR 1386
++ + P P P + P + P+ RA+ + P SK + +
Sbjct: 1219 QAGLAGPGPAGYSTARPTIPPRAGVI-------SAPQSHARASAGRLTPESQSKTSETSK 1271
Query: 1387 KTS---DPRRSIVECQPDASATPGVGTADSP----AAPTDSRDDQKGLSLSPQSPPERRG 1439
++ +P + P +S P P AAP Q L PQ PP R
Sbjct: 1272 GSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRS 1331
Query: 1440 YPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGE-GLRTADA-- 1496
L S+ +S P + T+ S + DL N+L+V + + ++T+
Sbjct: 1332 --SHSLPSE-ASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPT 1388
Query: 1497 --EKSSLSHPGIPP----SPPSCGPGSPLMPSR 1523
K + P S SC P P +P+R
Sbjct: 1389 PDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1421
Score = 36.2 bits (82), Expect = 0.32
Identities = 77/325 (23%), Positives = 124/325 (38%), Gaps = 57/325 (17%)
Query: 1337 ELDQKEPQ-MSPSVAASLSCPVPSTPPELS--QRATLDTVPPPP----PSKVGKRCRKTS 1389
E+++ PQ + PS ++ L PS+ P S Q T+ P P PS+ R
Sbjct: 1060 EVEELLPQHLQPSSSSGLGTS-PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPP 1118
Query: 1390 DPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQS--PPERRGYPGPGLRS 1447
+ S ++ QP ATP PA P + + ++P + P +R P G RS
Sbjct: 1119 SAQSSPIDAQP---ATPL--PQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARS 1173
Query: 1448 DWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRT-ADAEKSSLSHPGI 1506
+P + E GIG S ++ E E ++ K ++
Sbjct: 1174 P----AP-------------TRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP 1216
Query: 1507 PPSPPSCGPGS-------PLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTY 1559
P GPG P +P R + +ASA P S +++++ T+
Sbjct: 1217 SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLT-PESQSKTSETSKGSTF 1275
Query: 1560 EVE-LEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPE 1618
E L+ QA+ P+ + P + EPL + + + P L P P+
Sbjct: 1276 LPEPLKPQAAFPPQ---SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETP--------PQ 1324
Query: 1619 PTYVSPPCPRLSHSTPGKSRGQTYI 1643
P PP R SHS P ++ Q +
Sbjct: 1325 P----PPRSRSSHSLPSEASSQPQV 1345
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 55.1 bits (131), Expect = 7e-07
Identities = 114/519 (21%), Positives = 176/519 (33%), Gaps = 63/519 (12%)
Query: 1167 SPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCP 1226
S + TP+ HT T L TK T P P TW + ++ + +
Sbjct: 3095 STIHPSSTPETTHTS----TVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAA 3150
Query: 1227 APPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKD 1286
PT++ + TP + T P A + P T + RA K+
Sbjct: 3151 TGPTATPSS------TPGTTWILTEPSTTATVTVPTGSTA----TASSTRATAGTLKVLT 3200
Query: 1287 KAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMS 1346
TP + SS P T L P + +P S PS L ++S
Sbjct: 3201 STATTPTVISSRATPSSSPGTATAL---PALRSTATTPTATSVTAIPS-SSLGTAWTRLS 3256
Query: 1347 PSVA--ASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDAS- 1403
+ A++S PS+ PE +T+ T G +S P + P +
Sbjct: 3257 QTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTT 3316
Query: 1404 ----ATPGV--GTADSPAA--PTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPL 1455
ATP GTA +P T + +G +++P S P H ++ L
Sbjct: 3317 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIP-----------GTTHTATVL 3365
Query: 1456 LITSDT----EHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPP 1511
T+ T T S + G + + G T + S PG P PP
Sbjct: 3366 TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS-----STPGTTPIPP 3420
Query: 1512 --SCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASG 1569
+ +P S V ++ + + S +SP T SG
Sbjct: 3421 VLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSG 3480
Query: 1570 LPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRL 1629
+ L I S++ + + S+ + PALS P S ++ SPP P
Sbjct: 3481 I--LGTTHITEPSTVTSHTPAATTSTTQHST--PALSSPHPSSRTTE------SPPSP-- 3528
Query: 1630 SHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWT 1668
+TPG +RG + TP+ +ST P P T
Sbjct: 3529 GTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPIT 3567
Score = 51.6 bits (122), Expect = 7e-06
Identities = 107/462 (23%), Positives = 158/462 (34%), Gaps = 57/462 (12%)
Query: 1225 CPAPP-TSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQK 1283
CP+ P TSSTA P TP + T P A T LR A P K
Sbjct: 1888 CPSTPATSSTATPSS---TPGTTWILTKPTTTATTTASTGSTATPTSTLRTA----PPPK 1940
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
+ TP + SS P T L P + +P S PS L
Sbjct: 1941 VLTTTATTPTVTSSKATPSSSPGTATAL---PALRSTATTPTATSVTPIPS-SSLGTTWT 1996
Query: 1344 QMSPSVA--ASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPD 1401
++S + A++S PS+ PE + +T+ T G +S P + P
Sbjct: 1997 RLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT 2056
Query: 1402 A-----SATP--GVGTADSPAA--PTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHAS 1452
+ATP GTA +P T + +G +++P S P H +
Sbjct: 2057 TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIP-----------GTTHTA 2105
Query: 1453 SPLLITSDT----EHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPP 1508
+ L T+ T T S + G + + G T + S PG P
Sbjct: 2106 TVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTT-----NPSSTPGTTP 2160
Query: 1509 SPP--SCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQ 1566
PP + +P S V ++ + + + S +SP T
Sbjct: 2161 IPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSA 2220
Query: 1567 ASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPC 1626
SG+ L I S++ + L+ + + PALS P S T SPP
Sbjct: 2221 TSGI--LGTTHITEPSTVTSHTLAATTGTTQHST--PALSSPHPS------SRTTESPPS 2270
Query: 1627 PRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWT 1668
P +TPG + + TP+ +ST P P T
Sbjct: 2271 P--GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPIT 2310
Score = 47.8 bits (112), Expect = 1e-04
Identities = 106/507 (20%), Positives = 165/507 (32%), Gaps = 88/507 (17%)
Query: 1193 PRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPP 1252
P TP T P P TW + + + + T STA P TP + T P
Sbjct: 2418 PSTPATSSTAMPSSTPGTTW---ILTELTTTATTTESTGSTATPSS---TPGTTWILTEP 2471
Query: 1253 RAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLF 1312
A + P T A + A T P ++ ++P +P
Sbjct: 2472 STTATVTVPTGST--------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTAT 2523
Query: 1313 TSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVA--ASLSCPVPSTPPELSQRATL 1370
P + +P S PS L ++S + A++S PS+ PE +T+
Sbjct: 2524 ALPALRSTATTPTATSFTAIPS-SSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTV 2582
Query: 1371 DTVPPPPPSKVGKRCRKTSDP-----RRSIVECQPDASATPGVGTADSPAAP----TDSR 1421
T G +S P + + +ATP + P T +
Sbjct: 2583 LTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTT 2642
Query: 1422 DDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSN 1481
+G +++P S P +P ++T+ T V S A
Sbjct: 2643 PTTRGSTVTPSSIPGT-------------THTPTVLTTTTTTVATGSMATPSSSTQTSGT 2689
Query: 1482 VLSVEEGEGLRTADAEKSSLSH-PGIPPSPP--------------SCGPGSPL-----MP 1521
S+ TA ++ S PG P PP + P S L P
Sbjct: 2690 PPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 2749
Query: 1522 SRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPS 1581
+ TT GR S+ + +AW S S + T + +PS
Sbjct: 2750 VPNTTATTHGRSLSPSSP--HTVRTAWTSATSGTLGTTHIT----------------EPS 2791
Query: 1582 SSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQT 1641
+ P + ++ + PALS P S ++ SPP P +TPG +R +
Sbjct: 2792 TGTSHTPAATTGTT---QHSTPALSSPHPSSRTTE------SPPSP--GTTTPGHTRATS 2840
Query: 1642 YICQACTPTHGPSSTPSPFQTDGVPWT 1668
TP+ +ST P P T
Sbjct: 2841 RTTATATPSKTRTSTLLPSSPTSAPIT 2867
Score = 47.4 bits (111), Expect = 1e-04
Identities = 106/507 (20%), Positives = 163/507 (32%), Gaps = 88/507 (17%)
Query: 1193 PRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPP 1252
P TP T P P TW + + + + T STA P TP + T P
Sbjct: 3675 PSTPATSSTATPSSTPGTTW---ILTKLTTTATTTESTGSTATPSS---TPGTTWILTEP 3728
Query: 1253 RAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLF 1312
A + P T A + A T P ++ ++P +P
Sbjct: 3729 STTATVTVPTGST--------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTAT 3780
Query: 1313 TSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSV--AASLSCPVPSTPPELSQRATL 1370
P + +P S PS L ++S + A++S PS+ PE + +T+
Sbjct: 3781 ALPALRSTATTPTATSFTAIPS-SSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTV 3839
Query: 1371 DTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASAT-------PGVGTADSPAA--PTDSR 1421
T G +S P + P + T GTA +P T +
Sbjct: 3840 LTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTT 3899
Query: 1422 DDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSN 1481
G +++P S P +P ++T+ T V S A
Sbjct: 3900 PTTSGSTVTPSSVPGT-------------THTPTVLTTTTTTVATGSMATPSSSTQTSGT 3946
Query: 1482 VLS-VEEGEGLRTADAEKSSLSHPGIPPSPP--------------SCGPGSPL-----MP 1521
S + + + + S PG P PP + P S L P
Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 4006
Query: 1522 SRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPS 1581
+ TT GR S+ + +AW S S + T + +PS
Sbjct: 4007 VPNTTATTHGRSLSPSS--PHTVRTAWTSATSGTLGTTHI----------------TEPS 4048
Query: 1582 SSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQT 1641
+ P + ++ + PALS P S T SPP P +TPG + +
Sbjct: 4049 TGTSHTPAATTGTT---QHSTPALSSPHPS------SRTTESPPSP--GTTTPGHTTATS 4097
Query: 1642 YICQACTPTHGPSSTPSPFQTDGVPWT 1668
TP+ +ST P P T
Sbjct: 4098 RTTATATPSKTRTSTLLPSSPTSAPIT 4124
Score = 44.3 bits (103), Expect = 0.001
Identities = 112/483 (23%), Positives = 157/483 (32%), Gaps = 60/483 (12%)
Query: 1105 TPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQ-KSPAKMTPTKQAAFKESLKDSSSP 1163
TP+ +H ++ +K T R + + TP TP + T AA + SS+P
Sbjct: 3102 TPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 3161
Query: 1164 G-----HDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCT---WPHS 1215
G + + +T T T T + T P T P +
Sbjct: 3162 GTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGT 3221
Query: 1216 VNSSPESPSCPAPP--TSSTAQPRRECLTP-IRDPLRTPPRAAAFMGTPQN--QTHQQPH 1270
+ P S P TS TA P T R T P A TP + +T
Sbjct: 3222 ATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTST 3281
Query: 1271 VLRAARAEEPAQKLKDKAIKTP------KRPGNSTV--TSSPPVTPKKLFTSPLCDVSKK 1322
VL A TP K P +T T++P +P T P+ +
Sbjct: 3282 VLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTT 3341
Query: 1323 SPFRKSKIECPS--PGELDQKEP-QMSPSVAASLSCPVPS-------TPPELSQRATLDT 1372
+P + PS PG + + A+ S PS TPP L+ AT T
Sbjct: 3342 TPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTIT 3401
Query: 1373 VPPPPPSKVGKRCRKTSDPRRSIVECQPDASA---TP--GVGTADSPAAPTDSRDDQKGL 1427
+ P + P A++ TP +GT +P P + G
Sbjct: 3402 ATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTH-GR 3460
Query: 1428 SLSPQSPPERR---GYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLS 1484
SL P SP R G+ H + P +TS T T + H L S S
Sbjct: 3461 SLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAAT--TSTTQHSTPALSSPHPS 3518
Query: 1485 VEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLP 1544
E PPSP + PG SR T + + S L + P
Sbjct: 3519 SRTTES----------------PPSPGTTTPGHTRGTSRTTATATPSK-TRTSTLLPSSP 3561
Query: 1545 ASA 1547
SA
Sbjct: 3562 TSA 3564
Score = 42.7 bits (99), Expect = 0.003
Identities = 117/571 (20%), Positives = 183/571 (32%), Gaps = 108/571 (18%)
Query: 1193 PRTPKRQGTQPPGFLPNCTW------------------------------PHSVNSSPES 1222
P TP T P P TW P + S+ +
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034
Query: 1223 PSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAF-------MGT----PQNQTHQQP-- 1269
P+ + +S++ PR P+ T A +F +GT P+ T
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094
Query: 1270 ---HVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFR 1326
H + L KA T ST +S+P T + T + +
Sbjct: 3095 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT--WILTELTTAATTTAATG 3152
Query: 1327 KSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTV-----PPPPPSKV 1381
+ +PG PS A+++ P ST S RAT T+ P+ +
Sbjct: 3153 PTATPSSTPG---TTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI 3209
Query: 1382 GKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYP 1441
R +S P P +T TA S A S LS + P
Sbjct: 3210 SSRATPSSSP--GTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTAT--- 3264
Query: 1442 GPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSL 1501
+ + +S+P + + T T + G +V + G TA K
Sbjct: 3265 ---MSTATPSSTPETVHTSTVLTTTTTTTRATG------SVATPSSTPG--TAHTTKVPT 3313
Query: 1502 SHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEV 1561
+ + PS PG+ L P + TT ++ ++P + H+ + T V
Sbjct: 3314 TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTT-HTATVLTTTTTTV 3372
Query: 1562 ELEMQASGLPKLRIKKIDPSSSLEAEPL------SKEESSLGEESFLPAL----SMPRAS 1611
A+ + PS + A + + S+ G P L + P A+
Sbjct: 3373 ATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT 3432
Query: 1612 RSLSKPEP---TYVSPPCPRLSHSTPGKS--------------------RGQTYICQACT 1648
S P T +PP P + +T G+S G T+I + T
Sbjct: 3433 SSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 3492
Query: 1649 PT-HGPSSTPSPFQTDGVPWTPSPKHSGKTT 1678
T H P++T S Q P SP S +TT
Sbjct: 3493 VTSHTPAATTSTTQ-HSTPALSSPHPSSRTT 3522
Score = 42.7 bits (99), Expect = 0.003
Identities = 140/678 (20%), Positives = 218/678 (32%), Gaps = 135/678 (19%)
Query: 1077 ISPSEKGSA--RMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYT 1134
I S G+A R+ + + T TP+ H ++ + TT R + + TP T
Sbjct: 3243 IPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSST 3302
Query: 1135 PERLQKSPAKMTPTKQAAFKESLKDSSSPG-------------HDSPLDSKITPQKRHTQ 1181
P + K+ T F + SSSPG + S +TP
Sbjct: 3303 PGTAHTT--KVPTTTTTGF--TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 3358
Query: 1182 AGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECL 1241
T L T T P P S+ ++ + + T+ ++ P +
Sbjct: 3359 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 3418
Query: 1242 TPIRDPLRTPPRAAAFMGTPQN---QTH------------------QQPHVLRAARAEEP 1280
P+ T P A + TP + TH PH +R A
Sbjct: 3419 PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSAT 3478
Query: 1281 AQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQ 1340
+ L I P STVTS P +S P ++ PSPG
Sbjct: 3479 SGILGTTHITEP-----STVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPG---- 3529
Query: 1341 KEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVE--C 1398
+P S + P ++ +TL +P P TS P ++V C
Sbjct: 3530 ---TTTPGHTRGTSRTTATATPSKTRTSTL--LPSSP----------TSAPITTVVTTGC 3574
Query: 1399 QPDASAT-----------PGVGTADS----PAAPTDSRDDQKGLSLSPQSPPERRGYPGP 1443
+P + + P G D+ AA + GL Q+ P G P
Sbjct: 3575 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP---GVPLR 3631
Query: 1444 GLRSDWHASSPL-LITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLS 1502
L S L+ + E V ++ I V G T +
Sbjct: 3632 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEI-----RVFCCNYGHCPSTPATSST--- 3683
Query: 1503 HPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVE 1562
+ PS PG+ + ++ T ++A + P + W T+ ++ T V
Sbjct: 3684 ------ATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVP 3737
Query: 1563 LEMQA--------SGLPKLRIKKIDPS-SSLEAEPLSKEESSLGEESFLPAL-------- 1605
A +G P + P+ +S +A P SS G + LPAL
Sbjct: 3738 TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPF----SSPGTATALPALRSTATTPT 3793
Query: 1606 -----SMPRASRSLSKPEPTYVSPPCPRLS----HSTPGKSRGQTYICQACTPTHG---- 1652
++P +S + + + P +S STP + T + T T
Sbjct: 3794 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSV 3853
Query: 1653 --PSSTPSPFQTDGVPWT 1668
PSSTP T VP T
Sbjct: 3854 ATPSSTPGTAHTTKVPTT 3871
Score = 42.7 bits (99), Expect = 0.003
Identities = 131/599 (21%), Positives = 188/599 (31%), Gaps = 144/599 (24%)
Query: 1105 TPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTP-TKQAAFKESLKDSSSP 1163
TP+ +H ++ +K T R + + TP TP T T AA + SS+P
Sbjct: 4359 TPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4418
Query: 1164 GHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESP 1223
G L T L T T T P P TW + + P +
Sbjct: 4419 GTTWIL----------------TELTTTATTTASTGSTATPSSTPGTTW---ILTEPSTT 4459
Query: 1224 SCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQK 1283
+ PT STA T A GT PHV A
Sbjct: 4460 ATVTVPTGSTA---------------TASSTQATAGT--------PHVSTTA-------- 4488
Query: 1284 LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEP 1343
TP + SS P T L P + +P S PS L
Sbjct: 4489 ------TTPTVTSSKATPSSSPGTATAL---PALRSTATTPTATSFTAIPS-SSLGTTWT 4538
Query: 1344 QMSPSV--AASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPD 1401
++S + A++S PS+ PE +T+ T G +S P
Sbjct: 4539 RLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTP---------- 4588
Query: 1402 ASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDT 1461
GTA + PT + G + +P S P P + + ++ TS +
Sbjct: 4589 -------GTAHTTKVPTTT---TTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGS 4638
Query: 1462 EHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPS------------ 1509
H L + +V G + SS G PPS
Sbjct: 4639 TVTPSSIPGTTHTARVLTTTTTTVATG----SMATPSSSTQTSGTPPSLTTTATTITATG 4694
Query: 1510 ---PPSCGPG-SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEM 1565
PS PG +P+ P TT A++ +T S+SP+T
Sbjct: 4695 STTNPSSTPGTTPITPVLTSTATTPA-------------ATSSKATSSSSPRT------- 4734
Query: 1566 QASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPA-----LSMPRASRSLSKPEPT 1620
A+ LP L S++ P+ S+L +PA +S + S PE T
Sbjct: 4735 -ATTLPVL-TSTATKSTATSFTPI--PSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETT 4790
Query: 1621 YVSPPCPRLS------------HSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
+ S + ST G +R T + T T ST + T G W
Sbjct: 4791 HTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTW 4849
Score = 42.4 bits (98), Expect = 0.004
Identities = 110/542 (20%), Positives = 177/542 (32%), Gaps = 80/542 (14%)
Query: 1160 SSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSS 1219
SS+PG L + T G T++ + TP GT PP P + S+
Sbjct: 2987 SSTPGTTWILTEQTTAATTTATTGS-TAIPSSTP------GTAPP--------PKVLTST 3031
Query: 1220 PESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAF-------MGTPQNQTHQQPHVL 1272
+P+ + +S++ PR P+ T A +F +GT Q +
Sbjct: 3032 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPM 3091
Query: 1273 RAARAEEPAQK---------LKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKS 1323
P+ L KA T ST +S+P T + T + +
Sbjct: 3092 ATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT--WILTELTTAATTTA 3149
Query: 1324 PFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVP-----PPPP 1378
+ +PG PS A+++ P ST S RAT T+ P
Sbjct: 3150 ATGPTATPSSTPGTT---WILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTP 3206
Query: 1379 SKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERR 1438
+ + R +S P P +T TA S A S LS + P
Sbjct: 3207 TVISSRATPSSSP--GTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTAT 3264
Query: 1439 GYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEK 1498
+ + +S+P + + T T + G +V + G TA K
Sbjct: 3265 ------MSTATPSSTPETVHTSTVLTTTTTTTRATG------SVATPSSTPG--TAHTTK 3310
Query: 1499 SSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQT 1558
+ + PS PG+ L P + TT ++ ++P + +T + T
Sbjct: 3311 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 3370
Query: 1559 YEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPE 1618
M A P S ++S S + A+ S + P
Sbjct: 3371 TVATGSM--------------------ATPSSSTQTSGTPPSLTTTATTITATGSTTNPS 3410
Query: 1619 PTYVSPPCPRL---SHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSG 1675
T + P P + + +TP + A TH P + T G PS H+
Sbjct: 3411 STPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTV 3470
Query: 1676 KT 1677
+T
Sbjct: 3471 RT 3472
Score = 41.6 bits (96), Expect = 0.007
Identities = 136/652 (20%), Positives = 214/652 (32%), Gaps = 119/652 (18%)
Query: 1125 SHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGE 1184
SHTP T + +PA +P + ES SPG +P + T + T
Sbjct: 4052 SHTPAATTGTTQH--STPALSSPHPSSRTTES---PPSPGTTTPGHTTATSRTTATATPS 4106
Query: 1185 GTSLETKTPRTPKRQGTQPP-------GFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPR 1237
T T P +P T P G P C W ++ S P + + R
Sbjct: 4107 KTRTSTLLPSSP----TSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 4162
Query: 1238 RECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLR----AARAEEPAQKLK---DKAIK 1290
PL RA A G P + Q R E K K + I+
Sbjct: 4163 AAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 4222
Query: 1291 T--------PKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKE 1342
P P S+ T+ P TP + L +++ + S
Sbjct: 4223 VFCCNYGHCPSTPATSS-TAMPSSTPGTTWI--LTELTTTATTTAS-------------- 4265
Query: 1343 PQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDA 1402
+ S A S P + PP++ T P P+ + +S PR + +
Sbjct: 4266 ---TGSTATPSSTPGTAPPPKVL------TSPATTPTATSSKATSSSSPRTATTLPVLTS 4316
Query: 1403 SATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTE 1462
+AT T+ +P P+ + L PE+ P S H SS T +T
Sbjct: 4317 TATKSTATSVTP-IPSSTLGTTGTL-------PEQTTTP-VATMSTIHPSS----TPETT 4363
Query: 1463 HVT--LLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLM 1520
H + L ++A S S + T ++ + P + PS PG+ +
Sbjct: 4364 HTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 4423
Query: 1521 PSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQA--------SGLPK 1572
+ T ++A + P + W T+ ++ T V A +G P
Sbjct: 4424 LTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 4483
Query: 1573 LRIKKIDPS-SSLEAEPLSKEESSLGEESFLPAL-------------SMPRASRSLSKPE 1618
+ P+ +S +A P SS G + LPAL ++P +S +
Sbjct: 4484 VSTTATTPTVTSSKATP----SSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR 4539
Query: 1619 PTYVSPPCPRLSHSTPGKSRGQTYICQACTPT----------HGPSSTPSPFQTDGVPW- 1667
+ + P +S +TP + + T T PSSTP T VP
Sbjct: 4540 LSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTT 4599
Query: 1668 -------TPSPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLPGS 1712
TPS TP + W ++SG + +PG+
Sbjct: 4600 TTTGFTATPSSSPGTALTPPV---WISTTTTPTTTTPTTSGSTVTPSSIPGT 4648
Score = 38.5 bits (88), Expect = 0.063
Identities = 132/645 (20%), Positives = 208/645 (32%), Gaps = 121/645 (18%)
Query: 1094 TLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAF 1153
T+ + P++ TP+ +H ++ + T R + + TP TP + K+ T F
Sbjct: 3821 TMSTATPSS--TPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTT--KVPTTTTTGF 3876
Query: 1154 KESLKDSSSPG-----------------HDSPLDSKITPQKRHTQAGEGTSLET------ 1190
++ SSSPG S + P HT T+ T
Sbjct: 3877 --TVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM 3934
Query: 1191 KTPRTPKRQGTQPPGFLPNCT----WPHSVNSSPESPSCPAPP-----------TSSTAQ 1235
TP + + PP + T + N S + P PP TSST
Sbjct: 3935 ATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 3994
Query: 1236 PRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRP 1295
P T P+ P A G ++ + PH +R A + L I P
Sbjct: 3995 PSSALGTTHTPPV--PNTTATTHG--RSLSPSSPHTVRTAWTSATSGTLGTTHITEP--- 4047
Query: 1296 GNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSC 1355
ST TS P +S P ++ PSPG +P + S
Sbjct: 4048 --STGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPG-------TTTPGHTTATSR 4098
Query: 1356 PVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVE--CQPDASAT-------- 1405
+ P ++ +TL +P P TS P ++V C+P + +
Sbjct: 4099 TTATATPSKTRTSTL--LPSSP----------TSAPITTVVTTGCEPQCAWSEWLDYSYP 4146
Query: 1406 ---PGVGTADS----PAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPL-LI 1457
P G D+ AA + GL Q+ P G P L S L+
Sbjct: 4147 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP---GVPLGELGQVVECSLDFGLV 4203
Query: 1458 TSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGS 1517
+ E V ++ I V G T +++ PS PG+
Sbjct: 4204 CRNREQVGKFKMCFNYEI-----RVFCCNYGHCPSTPATSSTAM---------PSSTPGT 4249
Query: 1518 PLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKK 1577
+ + T ++A + P +A SP T +A+
Sbjct: 4250 TWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKAT--------- 4300
Query: 1578 IDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLS----HST 1633
SS A L S+ + + +P ++ + P + P +S ST
Sbjct: 4301 -SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSST 4359
Query: 1634 PGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTT 1678
P + T + T T SST +P T G W + + TT
Sbjct: 4360 PETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATT 4404
Score = 33.1 bits (74), Expect = 2.7
Identities = 68/317 (21%), Positives = 107/317 (33%), Gaps = 38/317 (11%)
Query: 1094 TLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAF 1153
T+ + P++ TP+ H ++ + T + + TP TP + K+ T F
Sbjct: 2564 TMSTATPSS--TPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTT--KVLTTTTTGF 2619
Query: 1154 KESLKDSSSPGHDSPLD-------------SKITPQKRHTQAGEGTSLETKTPRTPKRQG 1200
+ SSSPG L S +TP T L T T
Sbjct: 2620 TAT--PSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM 2677
Query: 1201 TQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGT 1260
P P S+ ++ + + T+ ++ P + P+ T P A + T
Sbjct: 2678 ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 2737
Query: 1261 PQN---QTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLC 1317
P + TH P + A + L +P P ++ T+ T L T+ +
Sbjct: 2738 PSSALGTTHTPP--VPNTTATTHGRSL------SPSSP-HTVRTAWTSATSGTLGTTHIT 2788
Query: 1318 DVSKKSPFRKSKIECPSPGELDQKEPQMS---PSVAASLSCPVPSTPPELSQRATLDTVP 1374
+ S + S + G P +S PS + S P P T RAT T
Sbjct: 2789 EPSTGT----SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTA 2844
Query: 1375 PPPPSKVGKRCRKTSDP 1391
PSK S P
Sbjct: 2845 TATPSKTRTSTLLPSSP 2861
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 54.3 bits (129), Expect = 1e-06
Identities = 65/262 (24%), Positives = 97/262 (37%), Gaps = 38/262 (14%)
Query: 1191 KTPRTPKRQGTQPPGF----LPNCTWPHSVNSSPESPS-CPAPPTSSTAQPRRECLTPIR 1245
K P + G PPG + T H + SP+ P+ P+PPT T QP + P +
Sbjct: 635 KPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQ 694
Query: 1246 DPLRTPPRAAAFMGTPQNQTHQQPHVLRAARA---EEPAQKLKDKAIKTPKRPGNSTVTS 1302
L P R ++ + Q H P A +P + + P G +
Sbjct: 695 --LSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSH 752
Query: 1303 SPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPP 1362
+PP TP T PL K++P P+P L P+ + A +L P P P
Sbjct: 753 TPPQTPTPPSTPPL---GKQNP------SLPAPQTLAGGNPETAQPHAGTL--PRPRPVP 801
Query: 1363 ELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRD 1422
+ R ++ PPPP G V D+S T TA ++SR
Sbjct: 802 KPRNRPSV----PPPPQPPG-------------VHSAGDSSLTNTAPTASKIVTDSNSRV 844
Query: 1423 DQKGLSLSPQSPPERRGYPGPG 1444
+ S+ P+ + PG
Sbjct: 845 SEPHRSIFPEMHSDSASKDVPG 866
Score = 40.8 bits (94), Expect = 0.013
Identities = 48/194 (24%), Positives = 68/194 (35%), Gaps = 22/194 (11%)
Query: 1193 PRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAP--PTSSTAQPRRECLTPIRDPLRT 1250
P++ + + + G +P+ SP S P P P S+ + I
Sbjct: 544 PQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQ 603
Query: 1251 PPRAAAF----MGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPV 1306
P AA MG P N PH LR A ++PA P PG + + +
Sbjct: 604 PQAAAGSHQLSMGQPHNAAGPSPHTLRRA-VKKPAPAPPKPGNPPPGHPGGQSSSGTSQH 662
Query: 1307 TPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQ 1366
P +S K P R PSP +P PS + LS P LS
Sbjct: 663 PP---------SLSPKPPTRS-----PSPPTQHTGQPPGQPSAPSQLSAP-RRYSSSLSP 707
Query: 1367 RATLDTVPPPPPSK 1380
+ PP PP++
Sbjct: 708 IQAPNHPPPQPPTQ 721
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 54.3 bits (129), Expect = 1e-06
Identities = 65/262 (24%), Positives = 97/262 (37%), Gaps = 38/262 (14%)
Query: 1191 KTPRTPKRQGTQPPGF----LPNCTWPHSVNSSPESPS-CPAPPTSSTAQPRRECLTPIR 1245
K P + G PPG + T H + SP+ P+ P+PPT T QP + P +
Sbjct: 557 KPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQ 616
Query: 1246 DPLRTPPRAAAFMGTPQNQTHQQPHVLRAARA---EEPAQKLKDKAIKTPKRPGNSTVTS 1302
L P R ++ + Q H P A +P + + P G +
Sbjct: 617 --LSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSH 674
Query: 1303 SPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPP 1362
+PP TP T PL K++P P+P L P+ + A +L P P P
Sbjct: 675 TPPQTPTPPSTPPL---GKQNP------SLPAPQTLAGGNPETAQPHAGTL--PRPRPVP 723
Query: 1363 ELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRD 1422
+ R ++ PPPP G V D+S T TA ++SR
Sbjct: 724 KPRNRPSV----PPPPQPPG-------------VHSAGDSSLTNTAPTASKIVTDSNSRV 766
Query: 1423 DQKGLSLSPQSPPERRGYPGPG 1444
+ S+ P+ + PG
Sbjct: 767 SEPHRSIFPEMHSDSASKDVPG 788
Score = 40.8 bits (94), Expect = 0.013
Identities = 44/164 (26%), Positives = 57/164 (34%), Gaps = 20/164 (12%)
Query: 1221 ESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAF----MGTPQNQTHQQPHVLRAAR 1276
ESP P P S+ + I P AA MG P N PH LR A
Sbjct: 496 ESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRA- 554
Query: 1277 AEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPG 1336
++PA P PG + + + P +S K P R PSP
Sbjct: 555 VKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPP---------SLSPKPPTRS-----PSPP 600
Query: 1337 ELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSK 1380
+P PS + LS P LS + PP PP++
Sbjct: 601 TQHTGQPPGQPSAPSQLSAP-RRYSSSLSPIQAPNHPPPQPPTQ 643
>gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
Length = 656
Score = 53.9 bits (128), Expect = 1e-06
Identities = 137/574 (23%), Positives = 202/574 (35%), Gaps = 143/574 (24%)
Query: 1200 GTQPPGFLPNC-TWPHSVNSSPESPSCPAPPTSST-----AQPRRECLTPIRDPLRTPPR 1253
GT+PP T P + PE+P PP +S+ +E L+ RD L P
Sbjct: 202 GTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLS--RDLLHRPSD 259
Query: 1254 AAAFMGT-PQNQTHQQPHVLRAARAEEPAQKLKD--KAIKTPKRPGNSTVTSSPPVTPKK 1310
A A G P QT + A R + A L +A + P+ P P P
Sbjct: 260 ALAKKGLGPFLQTAKP-----ARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPAT 314
Query: 1311 LFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATL 1370
L + P+ V + SP+R PV T P L+ +
Sbjct: 315 LPSEPVEGV-QASPWRPR---------------------------PVLPTHPALTLPVSS 346
Query: 1371 DTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTA---DSPAAPTDSRDDQKGL 1427
D P PP+ +R S++ P + T G+GT PA S +GL
Sbjct: 347 DASSPSPPAPRPER-------PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGL 399
Query: 1428 SLSPQSPPER-RGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVE 1486
S + PE G PG + P T E + H G+ + E
Sbjct: 400 SSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEEL-----VSHRSPGEPQETCSGTE 454
Query: 1487 EGEGLRTADA--EKSSLSHPGIPPSPPSC---GPGSPLMPSRDVHCTTDG-RQCQASAQL 1540
+T + + H + S PS GPG ++P+RD +T RQ SA L
Sbjct: 455 VERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWL 514
Query: 1541 DNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEES 1600
+ P + +G+P++R+ P + L EPL E
Sbjct: 515 SSGP---------------------ELTGMPRVRLAA--PLAVLPMEPLPPE-------- 543
Query: 1601 FLPALSMPRASRSLSKPEPTYV-SPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSP 1659
P +L PE + V P R S PG GQ G + T SP
Sbjct: 544 -------PVRPAALLTPEASSVGGPDQARYLESAPGWPVGQ--------EEWGVAHTSSP 588
Query: 1660 FQTDGVP-WTPSPKHSGKTTPDIIK-DWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLE 1717
T + W P +G P +++ ++P +GRG + L+
Sbjct: 589 PSTQTLSLWAP----TGVLLPSLVELEYP-----------FQAGRG----------ASLQ 623
Query: 1718 SEGKDHGLELSI--HRTPILEDFELEGVCQLPDQ 1749
E + L LS HR P L+D +EG+ + P +
Sbjct: 624 QELTEPTLALSAESHRPPELQD-SVEGLSERPSR 656
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 53.5 bits (127), Expect = 2e-06
Identities = 125/540 (23%), Positives = 180/540 (33%), Gaps = 110/540 (20%)
Query: 980 LHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRS 1039
+HR+ + SS P G P+ G P LS SRT + +F S + RS
Sbjct: 81 MHRKQELDSSHPPKQSG---RPPDPG-------RPAQPGLSKSRT-TDTFRSEQKLPGRS 129
Query: 1040 VQRVHSFQQDKS--DQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDS 1097
+ S ++ KS D +E S++ G +SE+ + S S K + +
Sbjct: 130 PSTI-SLKESKSRTDLKEEHK-------SSMMPGFLSEVNALSAVSSVVNKFNPFDLISD 181
Query: 1098 EVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESL 1157
+ +T KK QK + + P I P LQ+ P K P +Q ++ L
Sbjct: 182 SEASQEETTKK--QKVVQKEQGKPEGIIKPP---------LQQQPPKPIPKQQGPGRDPL 230
Query: 1158 KD----------------SSSPGHDSPLDSKI-TPQKRHTQAG----------------E 1184
+ S PG P+ TPQ H +
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290
Query: 1185 GTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSST---AQPRRECL 1241
G S++ P K QP P P S P PA P+ T AQ
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 1242 TPIRDPLRTPPRAAAF--MGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNST 1299
P++ P T P A P QT + +E+P K + K P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSE-----KPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 1300 VTSSPPV----TPKKLFTSPLCDVSKKSPF-RKSKIECPSPGEL------------DQKE 1342
+ PP TPK L P K+P K+ ++ P PG++ Q
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 1343 PQMSPSVAASLSCPVP------STPPELSQRATLDTVPP----PPPSKVGKRCRKTSDPR 1392
P PS + P P PP+ A + P PPP + G P
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 1393 RSIVECQPDASATPGVGTADSPAAPTDSRDDQ------KGLSLSPQS-PPERRGYPGPGL 1445
+ Q SA P SPA P+ + + G L P + P + P GL
Sbjct: 526 STKPPSQQPGSAKPS-AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Score = 47.8 bits (112), Expect = 1e-04
Identities = 101/474 (21%), Positives = 169/474 (35%), Gaps = 62/474 (13%)
Query: 1218 SSPESPSCPAPPTSST---AQPRRECLTPIRDPLRTPP--RAAAFMGTPQNQTHQQPHVL 1272
+S S S P P +S A P+++ L+ +P + PP + G+P + Q P
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQD-LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727
Query: 1273 RAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIEC 1332
++ P K P + V P PK + P D+ S +K +
Sbjct: 728 SLSKPAPP------KEPSVPSEQDKAPVADDKPKQPKMV--KPTTDLVSSSS-ATTKPDI 778
Query: 1333 PSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPR 1392
PS Q E + +P + + P S PP + + D+ P P+ K
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK--------- 829
Query: 1393 RSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGY---PGPGLRSDW 1449
I+ +S + G D + + Q +S P + P +G PGP +
Sbjct: 830 --IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 1450 HASSPLLITSDTE-------HVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLS 1502
+P E ++ +++A + V G G + +S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 1503 HPGIPPSPPSCGPGSPL--MPSRDVHCTTDGRQCQASAQLDNLPASA---WHSTDSASPQ 1557
G P GPG+P+ P+ T+ G +++ Q PA + T + + +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-KSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 1558 TYEVELEMQASGLPKLRIKKIDP----SSSLEAEPLSKEESSLGEESFLPALSMPRASRS 1613
E + E QA + + +K P S SL AEP + E+S P + P
Sbjct: 1007 KLEPKAE-QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP----- 1060
Query: 1614 LSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
L K E S P + T K++ +C C P+P T+ W
Sbjct: 1061 LCKTELNIGSKDPPNFNTCTECKNQ----VCNLC------GFNPTPHLTEIQEW 1104
Score = 45.1 bits (105), Expect = 7e-04
Identities = 116/614 (18%), Positives = 219/614 (35%), Gaps = 83/614 (13%)
Query: 1096 DSEVPAAYQTPKKSHQ----KSLSFSKTTP-----RRISHTPQTPLYTPERLQKSPAKMT 1146
+++ PAA + K+ Q K K P + ++ PQ + P +L+KSP +
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL-PTKLEKSPKPES 1057
Query: 1147 PTKQAAFKESLKDSSSPGHDSPLDSK--------ITPQKRHTQAGEGTSLETKTPRTPKR 1198
+ ++ P ++ + K P T+ E L +T R
Sbjct: 1058 TCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG 1117
Query: 1199 QGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQ----PRRECLTPIRDPLRTPPRA 1254
Q L + S P++ P P SS+ + P+ + + ++T
Sbjct: 1118 Q-------LGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEK 1170
Query: 1255 AAFMGTPQNQTHQQ-PHVLRAARAEEPAQKLKDKAI----KTPKRPGNSTVTSSPPVTPK 1309
+ + ++ P ++ + +E ++ KDKA K P + + +
Sbjct: 1171 VILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSE 1230
Query: 1310 KLFTSPLCDVSKKSPFRK-----SKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPEL 1364
+ PL + K +P K +K P + D + Q+ + P T E
Sbjct: 1231 E--KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG 1288
Query: 1365 SQRAT-LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDD 1423
Q T ++ +P P + K KT+ + + QP +A P P ++D
Sbjct: 1289 KQPQTKMEGLPSGTPQSLPKEDDKTTKTIKE--QPQPPCTAKPD---QVEPGKEKTEKED 1343
Query: 1424 QKGLSLSPQSPPERRGYPGPGLRSDWHASS----PLLITSDTEHVTL----------LSE 1469
K + S Q P +G G SD +SS P LI +D + + S
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 1470 AEHHGIGDLKSNVLSVEEGEGLRTAD--AEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHC 1527
+ + L+S VLS+ E + AD +EK + H P P L + ++
Sbjct: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1528 TTDGRQCQASAQLD--------NLPASAWH----------STDSASPQTYEVELEMQASG 1569
+ + + + D ++P+S H +T + E E + S
Sbjct: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP 1523
Query: 1570 LPKLRIKKIDPSSSLEAEPLSKEESSLGEESFL--PALSMPRASRSLSKPEPTYVSPPCP 1627
+P+ + + SSS + + S EE F+ + M + + ++
Sbjct: 1524 VPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLK 1583
Query: 1628 RLSHSTPGKSRGQT 1641
+S ST + + +T
Sbjct: 1584 EISSSTESQKKEET 1597
Score = 33.9 bits (76), Expect = 1.6
Identities = 34/129 (26%), Positives = 44/129 (34%), Gaps = 44/129 (34%)
Query: 1278 EEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGE 1337
E+PA +L P S SS P P+ F S D+S + P P P
Sbjct: 2370 EKPASQL----------PSGSPSVSSLPAKPRPFFRSSSLDISAQPP--------PPP-- 2409
Query: 1338 LDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVE 1397
P P P P PP PPPPP + T P++ +
Sbjct: 2410 -----PPPPP--------PPPPPPP-----------PPPPPLPPPTSPKPTILPKKKLTV 2445
Query: 1398 CQPDASATP 1406
P +ATP
Sbjct: 2446 ASPVTTATP 2454
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 53.5 bits (127), Expect = 2e-06
Identities = 125/540 (23%), Positives = 180/540 (33%), Gaps = 110/540 (20%)
Query: 980 LHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRS 1039
+HR+ + SS P G P+ G P LS SRT + +F S + RS
Sbjct: 81 MHRKQELDSSHPPKQSG---RPPDPG-------RPAQPGLSKSRT-TDTFRSEQKLPGRS 129
Query: 1040 VQRVHSFQQDKS--DQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDS 1097
+ S ++ KS D +E S++ G +SE+ + S S K + +
Sbjct: 130 PSTI-SLKESKSRTDLKEEHK-------SSMMPGFLSEVNALSAVSSVVNKFNPFDLISD 181
Query: 1098 EVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESL 1157
+ +T KK QK + + P I P LQ+ P K P +Q ++ L
Sbjct: 182 SEASQEETTKK--QKVVQKEQGKPEGIIKPP---------LQQQPPKPIPKQQGPGRDPL 230
Query: 1158 KD----------------SSSPGHDSPLDSKI-TPQKRHTQAG----------------E 1184
+ S PG P+ TPQ H +
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290
Query: 1185 GTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSST---AQPRRECL 1241
G S++ P K QP P P S P PA P+ T AQ
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 1242 TPIRDPLRTPPRAAAF--MGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNST 1299
P++ P T P A P QT + +E+P K + K P
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSE-----KPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 1300 VTSSPPV----TPKKLFTSPLCDVSKKSPF-RKSKIECPSPGEL------------DQKE 1342
+ PP TPK L P K+P K+ ++ P PG++ Q
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 1343 PQMSPSVAASLSCPVP------STPPELSQRATLDTVPP----PPPSKVGKRCRKTSDPR 1392
P PS + P P PP+ A + P PPP + G P
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 1393 RSIVECQPDASATPGVGTADSPAAPTDSRDDQ------KGLSLSPQS-PPERRGYPGPGL 1445
+ Q SA P SPA P+ + + G L P + P + P GL
Sbjct: 526 STKPPSQQPGSAKPS-AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Score = 47.8 bits (112), Expect = 1e-04
Identities = 101/474 (21%), Positives = 169/474 (35%), Gaps = 62/474 (13%)
Query: 1218 SSPESPSCPAPPTSST---AQPRRECLTPIRDPLRTPP--RAAAFMGTPQNQTHQQPHVL 1272
+S S S P P +S A P+++ L+ +P + PP + G+P + Q P
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQD-LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727
Query: 1273 RAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIEC 1332
++ P K P + V P PK + P D+ S +K +
Sbjct: 728 SLSKPAPP------KEPSVPSEQDKAPVADDKPKQPKMV--KPTTDLVSSSS-ATTKPDI 778
Query: 1333 PSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPR 1392
PS Q E + +P + + P S PP + + D+ P P+ K
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK--------- 829
Query: 1393 RSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGY---PGPGLRSDW 1449
I+ +S + G D + + Q +S P + P +G PGP +
Sbjct: 830 --IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 1450 HASSPLLITSDTE-------HVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLS 1502
+P E ++ +++A + V G G + +S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 1503 HPGIPPSPPSCGPGSPL--MPSRDVHCTTDGRQCQASAQLDNLPASA---WHSTDSASPQ 1557
G P GPG+P+ P+ T+ G +++ Q PA + T + + +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-KSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 1558 TYEVELEMQASGLPKLRIKKIDP----SSSLEAEPLSKEESSLGEESFLPALSMPRASRS 1613
E + E QA + + +K P S SL AEP + E+S P + P
Sbjct: 1007 KLEPKAE-QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP----- 1060
Query: 1614 LSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPW 1667
L K E S P + T K++ +C C P+P T+ W
Sbjct: 1061 LCKTELNIGSKDPPNFNTCTECKNQ----VCNLC------GFNPTPHLTEIQEW 1104
Score = 45.1 bits (105), Expect = 7e-04
Identities = 116/614 (18%), Positives = 219/614 (35%), Gaps = 83/614 (13%)
Query: 1096 DSEVPAAYQTPKKSHQ----KSLSFSKTTP-----RRISHTPQTPLYTPERLQKSPAKMT 1146
+++ PAA + K+ Q K K P + ++ PQ + P +L+KSP +
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL-PTKLEKSPKPES 1057
Query: 1147 PTKQAAFKESLKDSSSPGHDSPLDSK--------ITPQKRHTQAGEGTSLETKTPRTPKR 1198
+ ++ P ++ + K P T+ E L +T R
Sbjct: 1058 TCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG 1117
Query: 1199 QGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQ----PRRECLTPIRDPLRTPPRA 1254
Q L + S P++ P P SS+ + P+ + + ++T
Sbjct: 1118 Q-------LGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEK 1170
Query: 1255 AAFMGTPQNQTHQQ-PHVLRAARAEEPAQKLKDKAI----KTPKRPGNSTVTSSPPVTPK 1309
+ + ++ P ++ + +E ++ KDKA K P + + +
Sbjct: 1171 VILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSE 1230
Query: 1310 KLFTSPLCDVSKKSPFRK-----SKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPEL 1364
+ PL + K +P K +K P + D + Q+ + P T E
Sbjct: 1231 E--KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG 1288
Query: 1365 SQRAT-LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDD 1423
Q T ++ +P P + K KT+ + + QP +A P P ++D
Sbjct: 1289 KQPQTKMEGLPSGTPQSLPKEDDKTTKTIKE--QPQPPCTAKPD---QVEPGKEKTEKED 1343
Query: 1424 QKGLSLSPQSPPERRGYPGPGLRSDWHASS----PLLITSDTEHVTL----------LSE 1469
K + S Q P +G G SD +SS P LI +D + + S
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 1470 AEHHGIGDLKSNVLSVEEGEGLRTAD--AEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHC 1527
+ + L+S VLS+ E + AD +EK + H P P L + ++
Sbjct: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1528 TTDGRQCQASAQLD--------NLPASAWH----------STDSASPQTYEVELEMQASG 1569
+ + + + D ++P+S H +T + E E + S
Sbjct: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP 1523
Query: 1570 LPKLRIKKIDPSSSLEAEPLSKEESSLGEESFL--PALSMPRASRSLSKPEPTYVSPPCP 1627
+P+ + + SSS + + S EE F+ + M + + ++
Sbjct: 1524 VPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLK 1583
Query: 1628 RLSHSTPGKSRGQT 1641
+S ST + + +T
Sbjct: 1584 EISSSTESQKKEET 1597
Score = 33.9 bits (76), Expect = 1.6
Identities = 34/129 (26%), Positives = 44/129 (34%), Gaps = 44/129 (34%)
Query: 1278 EEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGE 1337
E+PA +L P S SS P P+ F S D+S + P P P
Sbjct: 2370 EKPASQL----------PSGSPSVSSLPAKPRPFFRSSSLDISAQPP--------PPP-- 2409
Query: 1338 LDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVE 1397
P P P P PP PPPPP + T P++ +
Sbjct: 2410 -----PPPPP--------PPPPPPP-----------PPPPPLPPPTSPKPTILPKKKLTV 2445
Query: 1398 CQPDASATP 1406
P +ATP
Sbjct: 2446 ASPVTTATP 2454
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 53.5 bits (127), Expect = 2e-06
Identities = 135/637 (21%), Positives = 221/637 (34%), Gaps = 85/637 (13%)
Query: 1091 SRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQ 1150
S ++ S P TP + ++ S TT S TP L P TP
Sbjct: 3179 SEDSTLSATPVDTSTPVTTSTEATS--STTAEGTSIPTSTPSEGMTPLTSVPVSNTPV-- 3234
Query: 1151 AAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNC 1210
A+ + S+ ++ ++PL + T EGTS+ T TP +G+ P +P
Sbjct: 3235 ASSEASILSTTPVDSNTPLTTS-TEASSSPPTAEGTSMPTSTPS----EGSTPLTSMPVS 3289
Query: 1211 TWPHSVNSSPESPSCPAPP-TSSTAQPRRECLTPIRDPLR----------TPPRAAAFMG 1259
T + + + + PA T T + PI D TP +F
Sbjct: 3290 TTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFST 3349
Query: 1260 TPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDV 1319
TP + P + ++ G S TSSP L + P+
Sbjct: 3350 TPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV--- 3406
Query: 1320 SKKSPFRKSKIECPSPGELDQK-------EPQMSPSVAASLSCP---------------V 1357
+P S++ S +D E SP++A S P +
Sbjct: 3407 -STTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL 3465
Query: 1358 PSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAP 1417
+TP S+ +TL T P + V S P + V P ++A G +
Sbjct: 3466 STTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS 3525
Query: 1418 TDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGD 1477
T + +LS +P + + S +SSP + T ++ SE G
Sbjct: 3526 TTPVASSEASTLS-TTPVDSNTFV---TSSSQASSSPATLQVTTMRMSTPSE----GSSS 3577
Query: 1478 LKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPP----SCGPGSPLMPSRDVHCTTDGRQ 1533
L + +LS +E S+ S P + S P + +P P +V
Sbjct: 3578 LTTMLLS-----STYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP--EVITLPMSTP 3630
Query: 1534 CQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEE 1593
+ S L +P S T S + AS LP + S+ + + P++ E
Sbjct: 3631 SEVSTPLTIMPVSTTSVTISEAG---------TASTLPVDTSTPVITSTQVSSSPVTPEG 3681
Query: 1594 SSL----GEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTP 1649
+++ E P +MP ++ ++ E + +S P + STP + + A
Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLS--TPSVVTSTPVTTSTEAISSSATLD 3739
Query: 1650 THGPS-STPSPFQTDG----VPWTPSPKHSGKTTPDI 1681
+ S S P T G V TP + +TP I
Sbjct: 3740 STTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSI 3776
Score = 48.5 bits (114), Expect = 6e-05
Identities = 136/675 (20%), Positives = 218/675 (32%), Gaps = 63/675 (9%)
Query: 1056 NSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQ---K 1112
NS S S S +MS +S S+ S +D+ P + S +
Sbjct: 499 NSMPTSTPSEGSTPLTSMS--VSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPE 556
Query: 1113 SLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSK 1172
S +TP S TP T + RL S T + A + +SS S ++
Sbjct: 557 GTSIPTSTPSEGS-TPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAE 615
Query: 1173 ITPQKRHTQAGEGT---SLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPP 1229
T T + GT S+ T + + + P + ++ S S A
Sbjct: 616 GTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG 675
Query: 1230 TSSTAQPRRECLTPIRD-PLRTPPRAAAFMGT-PQNQTHQQPHVLRAARAEEPAQKLKDK 1287
TS E TP+ P+ T A++ T V + A
Sbjct: 676 TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA 735
Query: 1288 AIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKS-------KIECPSPGELDQ 1340
++ T ST +S PV+ K L TS +P S + C
Sbjct: 736 SMPTSTPSEGSTPLTSMPVS-KTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGT 794
Query: 1341 KEPQMSPSVAASL--SCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVEC 1398
P +PS + L S PV TP + +TL T P S V +S P +
Sbjct: 795 SMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS 854
Query: 1399 QPDAS------------------ATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGY 1440
P ++ AT + T + P D+ + + SP G
Sbjct: 855 MPTSTYSEGRTPLTSMPVSTTLVATSAISTLST--TPVDTSTPVTNSTEARSSPTTSEGT 912
Query: 1441 PGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSS 1500
P + S+PL D+ + SEA + ++ E A + ++
Sbjct: 913 SMP-TSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE----ATSSPTT 967
Query: 1501 LSHPGIPPSPPSCG--PGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQT 1558
IP S PS G P + S + ++ + N P + S P
Sbjct: 968 AEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA 1027
Query: 1559 YEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRS----- 1613
+ + ++ S+++ A + S+ ++ P + +AS S
Sbjct: 1028 EGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTAD 1087
Query: 1614 -LSKPEPTYVS--------PPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDG 1664
S P TY P RL S+ + T + + T ++ SP +G
Sbjct: 1088 GTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG 1147
Query: 1665 VPWTPSPKHSGKTTP 1679
SP G TTP
Sbjct: 1148 TSIPTSPPSEG-TTP 1161
Score = 42.4 bits (98), Expect = 0.004
Identities = 130/687 (18%), Positives = 235/687 (34%), Gaps = 93/687 (13%)
Query: 1032 VSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGA-MSEMISPSEKGSARMKKR 1090
+S P S+ +F +P+ S + SL + MS ++ S + S+
Sbjct: 149 MSTPSEESISSTMAFVS-------TAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTP 201
Query: 1091 SRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQ 1150
T+ + TP S S ++ T + TP + + A +PT
Sbjct: 202 ESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS-AQASSSPT-- 258
Query: 1151 AAFKESLKDSSSPGHDSPLD----SKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGF 1206
A SL +S+ G +PL S + T T P + + P
Sbjct: 259 TAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTT 318
Query: 1207 LPNCTWPHSVNSSPESPSCPAPPTS---STAQPRRECLTPI-RDPLRTPPRAAAFMGTPQ 1262
+ P S + +P P ++ +T++ +TP+ L T + + T
Sbjct: 319 AEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTA 378
Query: 1263 NQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKK 1322
T L + P + I ++ TS+ PV K T+ S
Sbjct: 379 EATSMLTSTL--SEGSTPLTNMPVSTILVAS--SEASTTSTIPVDSKTFVTTASEASSSP 434
Query: 1323 SPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVG 1382
+ + I +P E S PV +TP S+ + L T P ++V
Sbjct: 435 TTAEDTSIATSTPSE----------GSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT 484
Query: 1383 KRCRKTSDPRRSIVECQPDASATPG-------------VGTADSPAAPTDSRDDQKGLSL 1429
+S P + V P ++ + G V ++++ T D ++
Sbjct: 485 TSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTT 544
Query: 1430 SPQSPPERRGYPGPGLRSDW--HASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVL---- 1483
S ++ G + + S+PL + + + SEA SN
Sbjct: 545 SSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTS 604
Query: 1484 -------SVEEGEGLRTADAEK-------SSLSHPGIPPSPPSCGPGSPLMPSRDVHCTT 1529
+ EG + T+ + S+S + S S +P+ + V +T
Sbjct: 605 SEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTST 664
Query: 1530 DGRQCQASAQLDNLPASAWHSTDSASPQT-----YEVELEMQASGLPKLRIKKIDP---S 1581
+ +A+ ++P S + T+ ++P T + +AS L + P S
Sbjct: 665 EATSSSTTAEGTSMPTSTY--TEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTS 722
Query: 1582 SSLEAEPLSKEESSL----GEESFLPALSMPRASRSLSKPEPTYVS-PPCPRLSHSTPGK 1636
+ + P + + +S+ E P SMP + L+ E + +S P +H T
Sbjct: 723 TEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHIT--- 779
Query: 1637 SRGQTYICQACTP-----THGPSSTPS 1658
T +C+P T P STPS
Sbjct: 780 ----TSTEASCSPTTTEGTSMPISTPS 802
Score = 42.4 bits (98), Expect = 0.004
Identities = 114/586 (19%), Positives = 194/586 (33%), Gaps = 47/586 (8%)
Query: 1124 ISHTP---QTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHT 1180
+S TP TP+ T SP T +L + ++P P+ + +
Sbjct: 2240 LSATPVDTSTPVTTSTEATSSPTTAEGTSIPT--STLSEGTTPLTSIPVSHTLVANSEVS 2297
Query: 1181 QAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRREC 1240
T +++ TP T + + PP + P S +S +P P S+T E
Sbjct: 2298 TLST-TPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTP-LTRMPVSTTMVASFET 2355
Query: 1241 LTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTV 1300
T L T P + T +Q P A++ + + P S
Sbjct: 2356 ST-----LSTTPADTSTPVTTYSQAGSSP-----TTADDTS--MPTSTYSEGSTPLTSVP 2403
Query: 1301 TSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSP---SVAASLSCPV 1357
S+ PV + T V +P S SP + SP S PV
Sbjct: 2404 VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 2463
Query: 1358 PSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPG---------- 1407
+TP S+ TL T P + + +S P + P ++A+ G
Sbjct: 2464 STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVS 2523
Query: 1408 ---VGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHA--SSPLLITSDTE 1462
V + ++ T D + S + G + + ++ S+PL +
Sbjct: 2524 TTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVST 2583
Query: 1463 HVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPS 1522
SEA + +++ E + K + S P PS S S L+ +
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDT-SMPISTPSEVSTSLTSILVST 2642
Query: 1523 RDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYE-VELEMQASGLPKLRIKKIDPS 1581
V + ++ +D + S+SP T E + G + I S
Sbjct: 2643 MPV--ASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVS 2700
Query: 1582 SSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQT 1641
++L A + S+ ++ P + AS S PT R+S + G + +
Sbjct: 2701 TTLLANSEASTLSTTPVDTSTPVTTSAEASSS-----PTTAEGTSMRISTPSDGSTPLTS 2755
Query: 1642 YICQACTPTHGPSSTPSPFQTD-GVPWTPSPKHSGKTTPDIIKDWP 1686
+ +ST S D +P T S + S T + P
Sbjct: 2756 ILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMP 2801
Score = 42.4 bits (98), Expect = 0.004
Identities = 100/484 (20%), Positives = 164/484 (33%), Gaps = 64/484 (13%)
Query: 1113 SLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSK 1172
S + S + P IS T L + + + P TP+ + + ++S G SP +
Sbjct: 3740 STTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLE 3799
Query: 1173 ITPQKRHTQAGEGTSLETK------TPRTPKRQGT--QPPGFLPNCTWPHSVNSSPESPS 1224
T + E ++L T + +P T PPG + + P ++ S S
Sbjct: 3800 GTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPG---DTSTPLLTSTKAGSFS 3856
Query: 1225 CPAPPTSSTAQPRRECLTPIRDPL---------------RTPPRAAAFMGTPQNQTHQQP 1269
PA T+ E TP+ L TPP + TP T P
Sbjct: 3857 IPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTP 3916
Query: 1270 HVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSP-FRKS 1328
+ A + I PG + S PVT P + +P +
Sbjct: 3917 TI-------PVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITST 3969
Query: 1329 KIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTV----PPPPPSKVGKR 1384
++ PS S S S S T P ++ A L V P P +
Sbjct: 3970 ELNTPSTS---------SSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRG 4020
Query: 1385 CRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPG 1444
C ++ A++TP T+ + T S + + +++ + P +P P
Sbjct: 4021 CTTSASTL--------SATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPT--FP-PA 4069
Query: 1445 LRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSS-LSH 1503
S +S T + E VT ++ ++ + T KS+ S
Sbjct: 4070 HSSTPPTTSASSTTVNPEAVTTMTTRTK---PSTRTTSFPTVTTTAVPTNTTIKSNPTST 4126
Query: 1504 PGIPPSPPSCGPGSPLMPSRDVH-CTTDGRQCQA-SAQLDNLPASAWHSTDSASPQTYEV 1561
P +P + G G SR + T DG +CQ + L S D P+T
Sbjct: 4127 PTVPRTTTCFGDGCQNTASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISA 4186
Query: 1562 ELEM 1565
++E+
Sbjct: 4187 QMEL 4190
Score = 42.0 bits (97), Expect = 0.006
Identities = 144/647 (22%), Positives = 214/647 (33%), Gaps = 87/647 (13%)
Query: 1077 ISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSK---------TTPRRISHT 1127
+S + S S +DS P T S S + +TP R
Sbjct: 2522 VSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPV 2581
Query: 1128 PQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTS 1187
PL + E S TP + + ++SS SP +K T T + TS
Sbjct: 2582 STKPLASSEA---STLSTTPVDTSIPVTTSTETSS----SPTTAKDTSMPISTPSEVSTS 2634
Query: 1188 LETKTPRT-------PKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRREC 1240
L + T T P T +SSP + + PTS+ + R
Sbjct: 2635 LTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGE-RSTP 2693
Query: 1241 LTPI--RDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPK---RP 1295
LT I L A+ TP + + A+ + A+ + I TP P
Sbjct: 2694 LTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMR-ISTPSDGSTP 2752
Query: 1296 GNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKE-PQMSPSVAAS-- 1352
S + S+ PV + T V P S SP + P +PS ++
Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812
Query: 1353 LSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTAD 1412
S PV TP S+ TL T P + V + +S P + P ++A+ G
Sbjct: 2813 TSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLT 2872
Query: 1413 S-PAAPTD-SRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEA 1470
S P + T + + LS +P P S +SSP + ++ SE
Sbjct: 2873 SIPVSTTPVASSEASTLSTTPVDTSI------PVTTSTEGSSSPTTAEGTSMPISTPSEV 2926
Query: 1471 EHHGIGDLKSNV-LSVEEGEGLR----------TADAEKSSLSHPGIPPSPPSCGPGSPL 1519
L S V ++ E L T AE SS S P PG
Sbjct: 2927 STPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERR 2986
Query: 1520 MPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKID 1579
P + +T ++ L PA D+++P T E
Sbjct: 2987 TPLTSMSVSTMPVASSEASTLSRTPA------DTSTPVTTSTEAS--------------- 3025
Query: 1580 PSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRG 1639
SS AE S+ E S P S+P ++ ++ PE + +S +TP S
Sbjct: 3026 -SSPTTAEGTGIPISTPSEGS-TPLTSIPVSTTPVAIPEASTLS--------TTPVDSNS 3075
Query: 1640 ----QTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPDII 1682
T + + TP G S S + P T P + T I
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAI 3122
Score = 41.2 bits (95), Expect = 0.010
Identities = 127/585 (21%), Positives = 201/585 (34%), Gaps = 58/585 (9%)
Query: 1097 SEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKES 1156
+ +P + T S +LS + R TP+ T + SP T +
Sbjct: 1929 TSIPVSTTTVASSEINTLSTTLADTR-------TPVTTYSQASSSPTTADGTSMPT--PA 1979
Query: 1157 LKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSV 1216
+ S+P PL + + + T ++T TP T +G+ P + S
Sbjct: 1980 YSEGSTPLTSMPLSTTLVVSSEASTLST-TPVDTSTPATTSTEGSSSPTTAGGTSIQTST 2038
Query: 1217 NSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAAR 1276
S +P P S+T E T P+ + + + T + + +A
Sbjct: 2039 PSERTTPLA-GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAP 2097
Query: 1277 AEEPAQKLKDKAIKTP-KRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSP 1335
+E TP P ST++++P + + TS +VS SP +
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITST--EVSS-SPIPTEGTSMQTS 2154
Query: 1336 GELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSI 1395
D++ P S PV +T S +TL T P + V S P S
Sbjct: 2155 TYSDRRTPLTS--------MPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 2206
Query: 1396 VECQPDASATPGVGTADSPAAPTDS----RDDQKGLSLSPQSPPERRGYPGPGLRSDWHA 1451
P ++TP G+ + P + + LS +P P S
Sbjct: 2207 GTSMP--TSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST------PVTTSTEAT 2258
Query: 1452 SSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPP 1511
SSP + + LSE G L S +S A++E S+LS + + P
Sbjct: 2259 SSPTTAEGTSIPTSTLSE----GTTPLTSIPVS-----HTLVANSEVSTLSTTPVDSNTP 2309
Query: 1512 ---SCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQAS 1568
S SP P+ + + + L +P S +T AS +T + +
Sbjct: 2310 FTTSTEASSP-PPTAEGTSMPTSTSSEGNTPLTRMPVS---TTMVASFETSTLSTTPADT 2365
Query: 1569 GLPKLRIKKIDPSSSLEAEPLSKEESSLGEES----FLPALSMPRASRSLSKPEPTYVSP 1624
P + SS A+ S S+ E S +P +MP S S T V
Sbjct: 2366 STPVTTYSQAG-SSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDT 2424
Query: 1625 PCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTP 1669
P ++ ST S T PT PS +P + V TP
Sbjct: 2425 STP-VTTSTEASS-SPTTAEGTSIPTSPPSEGTTPLASMPVSTTP 2467
Score = 40.8 bits (94), Expect = 0.013
Identities = 148/751 (19%), Positives = 255/751 (33%), Gaps = 123/751 (16%)
Query: 1141 SPAKMTPTKQ-----------AAFKESLKDSSSP----GHDSPLDSKITPQKRHTQAGEG 1185
S +MTPT+ F S +D+SSP G D P+ + T A
Sbjct: 106 SSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVS 165
Query: 1186 TS--------------LETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTS 1231
T+ ++ TP T Q + P + T P S NS +P + P S
Sbjct: 166 TAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTP-LTSMPAS 224
Query: 1232 STAQPRRECLTPIRDPLR-TPPRAAAFMGTPQNQTHQQPHVLRAARA--EEPAQKLKDKA 1288
+ E +T + P+ + P + + T + P + +A + P ++
Sbjct: 225 TMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSV 284
Query: 1289 IKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPS 1348
+ ST++++P T + TS + SP P+ + P
Sbjct: 285 MLVVSSEA-STLSTTPAATNIPVITS---TEASSSPTTAEGTSIPTSTYTEGSTP----- 335
Query: 1349 VAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGV 1408
S P + P S+ +TL P ++V + S+ P
Sbjct: 336 ---LTSTPASTMPVATSEMSTLSITPV---------------DTSTLVTTSTEPSSLPTT 377
Query: 1409 GTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTE-HVTLL 1467
A S T LS S P L + AS+ I D++ VT
Sbjct: 378 AEATSMLTST----------LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTA 427
Query: 1468 SEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHC 1527
SEA +++ + EG + +S + S S +P+ V
Sbjct: 428 SEASSSPTTAEDTSIATSTPSEG--STPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT 485
Query: 1528 TTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAE 1587
+T+ +A+++++P S ++ ++P T M S + P +S EA
Sbjct: 486 STEASSSPPTAEVNSMPTST--PSEGSTPLT-----SMSVSTM---------PVASSEAS 529
Query: 1588 PLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQAC 1647
L S+ ++ P + AS S + PE T + P S G T +
Sbjct: 530 TL----STTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP---------SEGSTPL---- 572
Query: 1648 TPTHGPSSTPSPFQTDG--VPWTPSPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEV 1705
T+ P ST ++ TP+ ++ TT + S RG
Sbjct: 573 --TNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTT 630
Query: 1706 GADLPGSLSLLESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRNSMPKAEEASSW 1765
+ S +L+ S ++ TP+ + + + S +
Sbjct: 631 ITSMSVSTTLVASSEAS-----TLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTE 685
Query: 1766 GQFGLSSR--KRVLLAKEEADRGAKRICDLREDSEVSKSKEGSPSWS-AWQLPSTGDEEV 1822
G L+S L+A EA + D S SP+ + +P++ E
Sbjct: 686 GSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSE- 744
Query: 1823 FVSGSTPPPSCAV-RSCLSASALQALTQSPL 1852
GSTP S V ++ L++S L+ +PL
Sbjct: 745 ---GSTPLTSMPVSKTLLTSSEASTLSTTPL 772
Score = 40.8 bits (94), Expect = 0.013
Identities = 171/837 (20%), Positives = 282/837 (33%), Gaps = 119/837 (14%)
Query: 1097 SEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKES 1156
S P TP + ++ S S TT S TP L +P T +
Sbjct: 945 SATPVDTSTPVTTSTEATS-SPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANS----- 998
Query: 1157 LKDSSSPGHDSPLDSKITPQKRHTQAG------EGTSLETKTPRTPKRQGTQPPGFLPNC 1210
+S +P+DS TP T+A EGTS+ T TP +G+ P +P
Sbjct: 999 ---EASTLSTTPVDSN-TPLTTSTEASSPPPTAEGTSMPTSTPS----EGSTPLTRMPVS 1050
Query: 1211 TW-------------------PHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRD-PLRT 1250
T P + S S S A TS E TP+ P+ T
Sbjct: 1051 TTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVST 1110
Query: 1251 ----PPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPV 1306
A+ TP + + V + A + +I T +T +S PV
Sbjct: 1111 RLVVSSEASTLSTTPVDTSIP---VTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 1167
Query: 1307 TPKKLFTSPLCDVSKKSPFRKSKI------ECPSPGELDQKEPQMSPSVAAS--LSCPVP 1358
+ + +S +S K+++ P P P +P ++ S PV
Sbjct: 1168 STTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVR 1227
Query: 1359 STPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPG--------VGT 1410
TP S+ +TL T P + V +S P + P ++ + G V T
Sbjct: 1228 HTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVST 1287
Query: 1411 --ADSPAAPT--DSRDDQKG-------LSLSPQSPPERRGYPGPGLRSDWHASSPLLITS 1459
SP A T + D KG +S SP +P E G + + ++ +TS
Sbjct: 1288 TLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP-TPAE-----GTSMPTSTYSEGRTPLTS 1341
Query: 1460 DTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIP--PSPPSCGPGS 1517
+ TL++ + ++LS + + S P S P+ P
Sbjct: 1342 IPVNTTLVASS--------AISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSE 1393
Query: 1518 PLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKK 1577
P + +T ++ L P D+++P T E + + I
Sbjct: 1394 GTTPLTSIPVSTTPVVSSEASTLSATP------VDTSTPGTTSAEATSSPTTAEGISIPT 1447
Query: 1578 IDPS---SSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTP 1634
PS + L++ P+S + E S L + S ++ + P S +
Sbjct: 1448 STPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAIS 1507
Query: 1635 GKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPDIIKDWPRRKRAVGC 1694
S G T A T ++T + + + + TP+ + TT P
Sbjct: 1508 TPSEGST----ALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSM 1563
Query: 1695 GAGSSSGRGEVGADLPGSLSLLESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRN 1754
+ S LP S L+ S + ++ TPI ++ + +
Sbjct: 1564 QTSTYSEGSTPLTSLPVSTMLVVSSEAN-----TLSTTPIDSKTQVTASTEASSSTTAEG 1618
Query: 1755 SMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLREDSEVSKSKEGSPSWSAWQL 1814
S S G L+S + + +S V S E S S
Sbjct: 1619 SSMTISTPSE-GSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS----PT 1673
Query: 1815 PSTGDE---EVFVSGSTPPPSCAVRSC-LSASALQALTQSPLLFQGKTPSSQSKDPR 1867
P+ G + G TP S VR+ +++SA+ L+ +P+ TP + S + R
Sbjct: 1674 PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPV--DNSTPVTTSTEAR 1728
Score = 39.3 bits (90), Expect = 0.037
Identities = 169/717 (23%), Positives = 242/717 (33%), Gaps = 90/717 (12%)
Query: 1097 SEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKES 1156
S P TP + K+ S S TT I T L P TP A E+
Sbjct: 2831 STTPVDTSTPVTTSTKASS-SPTTAEGIVVPISTASEGSTLLTSIPVSTTPV---ASSEA 2886
Query: 1157 LKDSSSPGHDSPLDSKITPQKRHTQAGEGTSL------ETKTPRTPKRQGTQPPGFLPNC 1210
S++P S + T EGTS+ E TP T T P
Sbjct: 2887 STLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAS 2946
Query: 1211 TWPHS-------VNSSPESPSCP--APPTSSTAQPRRECLTPIRD-PLRTPP----RAAA 1256
T + V +S E+ S P A TS E TP+ + T P A+
Sbjct: 2947 TLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAST 3006
Query: 1257 FMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSP----PVTPKKLF 1312
TP + + A+ + A+ I TP G++ +TS P PV +
Sbjct: 3007 LSRTPADTSTPVTTSTEASSSPTTAEGT-GIPISTPSE-GSTPLTSIPVSTTPVAIPEAS 3064
Query: 1313 TSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASL---SCPVPSTPPELSQRAT 1369
T V SP S SP + +S S PV +TP S +T
Sbjct: 3065 TLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIST 3124
Query: 1370 LDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDS----RDDQK 1425
L T P + V S P S P ++TP G+ P + +
Sbjct: 3125 LSTTPVDTSTPVTTSTEAHSSPTTSEGTSMP--TSTPSEGSTPLTYMPVSTMLVVSSEDS 3182
Query: 1426 GLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSE--AEHHGIGDLKSNVL 1483
LS +P S + + ++ +E +T L+ + + ++++L
Sbjct: 3183 TLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASIL 3242
Query: 1484 S---VEEGEGLRTADAEKSS---LSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQAS 1537
S V+ L T+ SS +P S PS GS + S V TT AS
Sbjct: 3243 STTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPS--EGSTPLTSMPVSTTT-----VAS 3295
Query: 1538 AQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLG 1597
++ L + D+++P V QAS P I +S+ S+ + L
Sbjct: 3296 SETSTLSTT---PADTSTP----VTTYSQASSSP-----PIADGTSMPTSTYSEGSTPLT 3343
Query: 1598 EESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTP 1657
SF + P S S T V P ++ ST S T PT PS
Sbjct: 3344 NMSF---STTPVVSSEASTLSTTPVDTSTP-VTTSTEA-SLSPTTAEGTSIPTSSPSEGT 3398
Query: 1658 SPFQTDGVPWTP---SPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLS 1714
+P + V TP S ++ TTP SSS G LP S +
Sbjct: 3399 TPLASMPVSTTPVVSSEVNTLSTTP-----VDSNTLVTTSTEASSSPTIAEGTSLPTSTT 3453
Query: 1715 LLESEGKDHGLELSIHRTPILEDFELEGVCQLP-------DQSPPRNSMPKAEEASS 1764
SEG + + TP+ E + P S P NS P E +S
Sbjct: 3454 ---SEGSTPLSIMPLSTTPVASS-EASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTS 3506
Score = 38.9 bits (89), Expect = 0.049
Identities = 118/581 (20%), Positives = 209/581 (35%), Gaps = 82/581 (14%)
Query: 1097 SEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKES 1156
S P TP + ++ S S TT IS TP L+ P TP + + S
Sbjct: 1417 SATPVDTSTPGTTSAEATS-SPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANS--EAS 1473
Query: 1157 LKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSV 1216
++ +SP+ + T A EGTS+ TP T P +
Sbjct: 1474 TLSTTPVDSNSPVVTSTAVSSSPTPA-EGTSIAISTPSEGSTALTSIPVSTTTVA-SSEI 1531
Query: 1217 NSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAAR 1276
NS +P+ + P ++ +Q A+ T + T Q +
Sbjct: 1532 NSLSTTPAVTSTPVTTYSQ-------------------ASSSPTTADGTSMQTSTY--SE 1570
Query: 1277 AEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPG 1336
P L + N T++++P + ++ S S + I PS G
Sbjct: 1571 GSTPLTSLPVSTMLVVSSEAN-TLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG 1629
Query: 1337 ELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIV 1396
SP + S PV +TP + +TL T P S V I
Sbjct: 1630 ---------SPLLT---SIPVSTTPVASPEASTLSTTPVDSNSPV-------------IT 1664
Query: 1397 ECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLL 1456
+ +S TP GT+ + T+ R +P + R P +++P+
Sbjct: 1665 STEVSSSPTPAEGTSMPTSTYTEGR--------TPLTSITVRTTPVASSAISTLSTTPV- 1715
Query: 1457 ITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPG 1516
++ VT +EA +++ + EG T +S + S S
Sbjct: 1716 --DNSTPVTTSTEARSSPTTSEGTSMPNSTPSEG--TTPLTSIPVSTTPVLSSEASTLSA 1771
Query: 1517 SPLMPSRDVHCTTDGRQCQASAQLDNLPASAWH---STDSASPQTYEVELEMQASGLPKL 1573
+P+ S V +T+ +A+ ++P S + +++P ++ + +AS L
Sbjct: 1772 TPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTT 1831
Query: 1574 RIKKIDP---SSSLEAEPLSKEESSLG----EESFLPALSMPRASRSLSKPEPTYVSPPC 1626
+ P S+++ + P E +S+ E S+P ++ +++ E +S
Sbjct: 1832 PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLS-TT 1890
Query: 1627 PRLSHSTPGKSRGQTYICQACTPTHGP-SSTPSPFQTDGVP 1666
P ++ STP TY + +PT SS P+ +G P
Sbjct: 1891 PAVT-STP----VTTYAQVSSSPTTADGSSMPTSTPREGRP 1926
Score = 38.1 bits (87), Expect = 0.083
Identities = 117/547 (21%), Positives = 181/547 (33%), Gaps = 66/547 (12%)
Query: 1159 DSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRT-------------PKRQGTQPPG 1205
DS++P S S P T TS E TP T T P
Sbjct: 2305 DSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPAD 2364
Query: 1206 FLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRD-PLRTPP----RAAAFMGT 1260
T SSP + + PTS+ + E TP+ P+ T P A+ T
Sbjct: 2365 TSTPVTTYSQAGSSPTTADDTSMPTSTYS----EGSTPLTSVPVSTMPVVSSEASTHSTT 2420
Query: 1261 PQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSP----PVTPKKLFTSPL 1316
P + + P + P +P G + + S P PV + T
Sbjct: 2421 PVDTS--TPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLST 2478
Query: 1317 CDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASL---SCPVPSTPPELSQRATLDTV 1373
V +P S SP + +S + S S PV +TP + +TL T
Sbjct: 2479 TPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTT 2538
Query: 1374 PPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQS 1433
P S V +S + P ++ + G S T + +LS +
Sbjct: 2539 PVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLS-TT 2597
Query: 1434 PPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNV-LSVEEGEGLR 1492
P + P S +SSP + ++ SE L S + ++ E L
Sbjct: 2598 PVDT---SIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLS 2654
Query: 1493 TADAEKSSL--SHPGIPPSP--------PSCGPGSPLMPSRDVHCTTDGRQCQASAQLDN 1542
T + +L + G SP P+ PG P ++ +T ++ L
Sbjct: 2655 TTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST 2714
Query: 1543 LPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFL 1602
P D+++P T E + ++ PS + PL+ +
Sbjct: 2715 TP------VDTSTPVTTSAEASSSPTTAEGTSMRISTPSDG--STPLTS----------I 2756
Query: 1603 PALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQT 1662
++P AS S T V P ++ ST S T + PT PS T +P +
Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIP-VTTSTEASSSPTTAEVTS-MPTSTPSETSTPLTS 2814
Query: 1663 DGVPWTP 1669
V TP
Sbjct: 2815 MPVNHTP 2821
Score = 34.3 bits (77), Expect = 1.2
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Query: 343 KGSVAQWSLPTSSTL--GTDSWMLGSPEESTATQRLLFQQLVSRLTAEELHLVADVDPGE 400
+GS A S+P S+T +++ L + T+T + Q+ S T + + P E
Sbjct: 1864 EGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPRE 1923
Query: 401 GRPPITGV-ISPLSASAMILTVCRTKEAEFQRHVLQTAVADSPRDTA 446
GRPP+T + +S + ++ + T A+ + V + A S TA
Sbjct: 1924 GRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTA 1970
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,452,046
Number of Sequences: 37866
Number of extensions: 4694854
Number of successful extensions: 22414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 860
Number of HSP's that attempted gapping in prelim test: 17792
Number of HSP's gapped (non-prelim): 4107
length of query: 1910
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1793
effective length of database: 13,817,196
effective search space: 24774232428
effective search space used: 24774232428
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.