BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo sapiens] (374 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom... 763 0.0 gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ... 464 e-131 gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 358 3e-99 gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 354 8e-98 gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 327 1e-89 gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] 296 2e-80 gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec... 226 3e-59 gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] 207 1e-53 gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 181 1e-45 gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec... 159 3e-39 gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] 154 2e-37 gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] 152 4e-37 gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 132 7e-31 gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 130 1e-30 gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec... 115 8e-26 gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] 71 1e-12 gi|11225258 myelin associated glycoprotein isoform a precursor [... 64 2e-10 gi|18104957 myelin associated glycoprotein isoform b precursor [... 64 2e-10 gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens] 62 1e-09 gi|13489095 sialoadhesin precursor [Homo sapiens] 56 5e-08 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 55 1e-07 gi|109150416 peroxidasin [Homo sapiens] 55 1e-07 gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 52 7e-07 gi|62988340 leucine rich repeat containing 22 [Homo sapiens] 49 1e-05 gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 48 2e-05 gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 47 3e-05 gi|15147240 brother of CDO [Homo sapiens] 46 6e-05 gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 45 8e-05 gi|110349719 titin isoform N2-A [Homo sapiens] 44 2e-04 gi|110349717 titin isoform novex-2 [Homo sapiens] 44 2e-04 >gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo sapiens] Length = 374 Score = 763 bits (1969), Expect = 0.0 Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 Query: 121 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLR 180 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLR Sbjct: 121 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLR 180 Query: 181 LVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSL 240 LVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSL Sbjct: 181 LVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSL 240 Query: 241 NLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDI 300 NLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDI Sbjct: 241 NLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDI 300 Query: 301 GMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQ 360 GMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQ Sbjct: 301 GMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQ 360 Query: 361 EATNNEYSEIKIPK 374 EATNNEYSEIKIPK Sbjct: 361 EATNNEYSEIKIPK 374 >gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo sapiens] Length = 467 Score = 464 bits (1194), Expect = e-131 Identities = 231/236 (97%), Positives = 234/236 (99%) Query: 139 LSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 198 + +NV+ PPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR Sbjct: 232 IQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 291 Query: 199 SLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGV 258 SLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGV Sbjct: 292 SLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGV 351 Query: 259 LLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLT 318 LLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLT Sbjct: 352 LLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLT 411 Query: 319 ESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK 374 ESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK Sbjct: 412 ESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK 467 Score = 307 bits (787), Expect = 9e-84 Identities = 163/246 (66%), Positives = 181/246 (73%), Gaps = 14/246 (5%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 Query: 121 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLR 180 YFFRMEKGNIKWNYKYDQLSVNVT + + GT + + + SV Sbjct: 121 YFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILI---PGTLESGCFQNLTCSV------- 170 Query: 181 LVCAVDSNPPARLSWTWRSLT-LYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVS 239 A + P +SW S++ L+PS + ++ + TC Q +L V+ Sbjct: 171 -PWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTC--QVTLPGAGVT 227 Query: 240 LNLSLQ 245 N ++Q Sbjct: 228 TNRTIQ 233 >gi|16506826 sialic acid binding immunoglobulin-like lectin-like protein 1 isoform b precursor [Homo sapiens] Length = 477 Score = 358 bits (920), Expect = 3e-99 Identities = 227/477 (47%), Positives = 266/477 (55%), Gaps = 107/477 (22%) Query: 5 LLLPLLWGRERVEG-----------QKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVD 53 +LLPLLW E + + Y L + SVTVQEG+CV V CS YP Sbjct: 1 MLLPLLWANEERDSGGWADPRFSTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHY 60 Query: 54 SQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDA 113 + T S PV+G WF+ G DI W PVATN P+ VQE+T RF LLGDPQT NC+LSIRDA Sbjct: 61 NWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 120 Query: 114 RMSDAGRYFFRMEKGNIKWNYKYDQLSVNVT----------------DPPQNLTVTV--- 154 R D+G+Y+F++E+G+ KWNY YD+LSV+VT P+NLT +V Sbjct: 121 RKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWA 180 Query: 155 -FQGEGTASTALG-----------NSSSLSVL---EGQSLRLVCAVD------------- 186 QG T +G SS LS++ + L C V Sbjct: 181 CEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVR 240 Query: 187 ---SNPPARLSWT----------------------WRSLTLYPSQPSNPL---------- 211 S PP L+ T +SL L + SNP Sbjct: 241 LNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSL 300 Query: 212 -----------VLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVL 259 VLEL +VH+ DEGEFTCRAQN LGSQH+SL+LSLQ EYTGKMRP+SGV Sbjct: 301 TLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVT 360 Query: 260 LGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTE 319 LGA GGAGATALVFL FC+IF+VVRSCRKKSARPA VGD GM+DAN +RGSASQG L E Sbjct: 361 LGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIE 420 Query: 320 SWADDNPRHHG--LAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK 374 S ADD+P HH A S EE EIQYA LSFHK PQ QEA EYSEI IPK Sbjct: 421 SPADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK 477 >gi|16506828 sialic acid binding immunoglobulin-like lectin-like protein 1 isoform a precursor [Homo sapiens] Length = 595 Score = 354 bits (908), Expect = 8e-98 Identities = 220/445 (49%), Positives = 256/445 (57%), Gaps = 96/445 (21%) Query: 26 YSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAW 85 Y L + SVTVQEG+CV V CS YP + T S PV+G WF+ G DI W PVATN P+ Sbjct: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 210 Query: 86 AVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVT- 144 VQE+T RF LLGDPQT NC+LSIRDAR D+G+Y+F++E+G+ KWNY YD+LSV+VT Sbjct: 211 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTA 270 Query: 145 ---------------DPPQNLTVTV----FQGEGTASTALG-----------NSSSLSVL 174 P+NLT +V QG T +G SS LS++ Sbjct: 271 LTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLI 330 Query: 175 ---EGQSLRLVCAVD----------------SNPPARLSWT------------------- 196 + L C V S PP L+ T Sbjct: 331 PQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALS 390 Query: 197 ---WRSLTLYPSQPSNPL---------------------VLEL-QVHLGDEGEFTCRAQN 231 +SL L + SNP VLEL +VH+ DEGEFTCRAQN Sbjct: 391 VLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQN 450 Query: 232 SLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSA 291 LGSQH+SL+LSLQ EYTGKMRP+SGV LGA GGAGATALVFL FC+IF+VVRSCRKKSA Sbjct: 451 PLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSA 510 Query: 292 RPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHSSGEEREIQYAPLSF 349 RPA VGD GM+DAN +RGSASQG L ES ADD+P HH A S EE EIQYA LSF Sbjct: 511 RPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSF 570 Query: 350 HKGEPQDLSGQEATNNEYSEIKIPK 374 HK PQ QEA EYSEI IPK Sbjct: 571 HKARPQYPQEQEAIGYEYSEINIPK 595 Score = 208 bits (530), Expect = 6e-54 Identities = 105/144 (72%), Positives = 115/144 (79%), Gaps = 4/144 (2%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 +LLLLL PLL GR + QK DY LTMQ SVTVQEG+CV V CSFSYP + T SDP Sbjct: 3 LLLLLLPPLLCGRVGAKEQK----DYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDP 58 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHGYWFRAG+ +S PVATNNPA AVQEETRDRFHLLGDPQ K+CTLSIRD R SDAG Sbjct: 59 VHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGT 118 Query: 121 YFFRMEKGNIKWNYKYDQLSVNVT 144 Y F +E+GN+KWNYKYDQLSVNVT Sbjct: 119 YVFCVERGNMKWNYKYDQLSVNVT 142 >gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] Length = 499 Score = 327 bits (837), Expect = 1e-89 Identities = 174/237 (73%), Positives = 195/237 (82%), Gaps = 3/237 (1%) Query: 141 VNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL 200 ++V+ PP NLT+TVFQG+ TASTALGN SSLSVLEGQSLRLVCAV+SNPPARLSWT SL Sbjct: 241 LDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSL 300 Query: 201 TLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVL 259 TL PS+ SNP +LEL +VH+ DEGEFTCRAQN+ GSQH+SL+LSLQ E TG RPVS V Sbjct: 301 TLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVT 360 Query: 260 LGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTE 319 L AVGGAGATAL FLSFC+IFI+VRSCRKKSARPAA VGD GM+DA IRGSASQG LTE Sbjct: 361 LAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTE 420 Query: 320 SWADDNP--RHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK 374 SW D NP + A SSGEE E+ YA LSFHK +PQD GQEAT++EYSEIKI K Sbjct: 421 SWKDGNPLKKPPPAVAPSSGEEGELHYATLSFHKVKPQDPQGQEATDSEYSEIKIHK 477 Score = 184 bits (466), Expect = 1e-46 Identities = 112/234 (47%), Positives = 138/234 (58%), Gaps = 16/234 (6%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 +LLLLLLPLLWG + +EG + Y L +Q VTVQEG+CVHV CSFSYP D TDSDP Sbjct: 2 LLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDP 61 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHGYWFRAG+ APVATNNP VQ ET+ RF LLGD + +C+LSIRDAR D G Sbjct: 62 VHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGS 121 Query: 121 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLE-GQSL 179 YFFR+E+G++KW+YK QL+ + L+V V TA T + L LE G S Sbjct: 122 YFFRLERGSMKWSYK-SQLNYKT----KQLSVFV-----TALTHRPDILILGTLESGHSR 171 Query: 180 RLVCAV----DSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCR 228 L C+V P +SW S++ + VL L D G TC+ Sbjct: 172 NLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQ 225 >gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] Length = 463 Score = 296 bits (759), Expect = 2e-80 Identities = 165/238 (69%), Positives = 184/238 (77%), Gaps = 12/238 (5%) Query: 141 VNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVD---SNPPARLSWTW 197 +NV+ PPQNLT+TVFQG+GT ST LGN SSLS+ EGQSLRLVCAVD SNPPARLS +W Sbjct: 230 LNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSW 289 Query: 198 RSLTLYPSQPSNPLVLELQ-VHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVS 256 R LTL PSQPSNP VLEL VHL D EFTCRAQN LGSQ V LN+SLQ + T S Sbjct: 290 RGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQSKAT------S 343 Query: 257 GVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGN 316 GV G VGGAGATALVFLSFCVIF+VVRSCRKKSARPAA VGD G++DAN +RGSASQG Sbjct: 344 GVTQGVVGGAGATALVFLSFCVIFVVVRSCRKKSARPAAGVGDTGIEDANAVRGSASQGP 403 Query: 317 LTESWADDNP--RHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKI 372 LTE WA+D+P + +A SS E E+QYA LSF +P D GQEAT+ EYSEIKI Sbjct: 404 LTEPWAEDSPPDQPPPASARSSVGEGELQYASLSFQMVKPWDSRGQEATDTEYSEIKI 461 Score = 216 bits (549), Expect = 3e-56 Identities = 125/229 (54%), Positives = 142/229 (62%), Gaps = 17/229 (7%) Query: 2 LLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPV 61 +LLLLLPLLWGRER EGQ S LTMQSSVTVQEG+CVHV CSFSYP PV Sbjct: 1 MLLLLLPLLWGRERAEGQTSKL----LTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPV 56 Query: 62 -HGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 HGYWFR G + APVATNNPA AV EETRDRFHLLGDP TKNCTLSIRDAR SDAGR Sbjct: 57 VHGYWFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGR 116 Query: 121 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLR 180 YFFRMEKG+IKWNYK+ +LSVNVT + + GT + + + SV Sbjct: 117 YFFRMEKGSIKWNYKHHRLSVNVTALTHRPNILI---PGTLESGCPQNLTCSV------- 166 Query: 181 LVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCR 228 A + P +SW S++ + VL L D G TC+ Sbjct: 167 -PWACEQGTPPMISWIGTSVSPLDPSTTRSSVLTLIPQPQDHGTSLTCQ 214 >gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 precursor [Homo sapiens] Length = 437 Score = 226 bits (576), Expect = 3e-59 Identities = 170/451 (37%), Positives = 223/451 (49%), Gaps = 103/451 (22%) Query: 2 LLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPV 61 +L LLLPLLW G + + + L S+TVQEG+CV V C + + Sbjct: 12 MLPLLLPLLWA-----GALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYG--- 63 Query: 62 HGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRY 121 +GYWF G D+ PVATN+P VQEETR RFHLL DP+ KNC+LSIRDAR D Y Sbjct: 64 YGYWFLEGADV----PVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAY 119 Query: 122 FFRMEKGNIKWNYKYDQLSV---------NVTDP-------PQNLTVTV----------- 154 FFR++ +K+ Y +LSV N++ P P NLT +V Sbjct: 120 FFRLKSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPI 179 Query: 155 FQGEGTASTALG------------------------------------------------ 166 F A T+LG Sbjct: 180 FSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSSFKI 239 Query: 167 --NSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEG 223 N+SSL VLEGQ+LRL+C D NPPA LSW L + SN VLEL QV +EG Sbjct: 240 LQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEG 299 Query: 224 EFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVV 283 +FTCRAQ+ LGS +SL+L + + G+ +G +LGAV GA T LVFL C IF V Sbjct: 300 DFTCRAQHPLGSLQISLSLFVHWKPEGR----AGGVLGAVWGASITTLVFLCVCFIF-RV 354 Query: 284 RSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQ 343 ++ RKK+A+P + D+ N + S S+G+ + H A S +E+E+ Sbjct: 355 KTRRKKAAQPVQNTDDV-----NPVMVSGSRGHQHQFQTGIVSDHPAEAGPISEDEQELH 409 Query: 344 YAPLSFHKGEPQDLSGQEATNNEYSEIKIPK 374 YA L FHK +PQ+ + T+ EYSEIKI K Sbjct: 410 YAVLHFHKVQPQE---PKVTDTEYSEIKIHK 437 >gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] Length = 364 Score = 207 bits (527), Expect = 1e-53 Identities = 146/398 (36%), Positives = 199/398 (50%), Gaps = 63/398 (15%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 M LLLLLPLLW G + ++ L +Q SVTVQEG+CV V C+F +P+ + P Sbjct: 1 MPLLLLLPLLWA-----GALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSP 55 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHGYWFR G IS +PVATN VQEET+ RF LLGDP NC+LSI DAR D G Sbjct: 56 VHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGS 115 Query: 121 YFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLR 180 YFFRME+G+ K++YK QLSV+VTD + + GT G S Sbjct: 116 YFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILI---PGTLE------------PGHSKN 160 Query: 181 LVCAV----DSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCRAQNSLGS 235 L C+V + P SW + T + ++ VL + D G TC+ + + Sbjct: 161 LTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAG 220 Query: 236 QHVSLNLSLQQEY--------------TGKMRPVSGVLLGAVGGAGATALVFLSFCVIFI 281 + L Y +GK +GV+ GA+GGAG TAL+ L C+IF Sbjct: 221 VTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFF 280 Query: 282 VVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGE--- 338 +V++ R+K+AR A +G D + GSAS + +S + HG SS Sbjct: 281 IVKTHRRKAARTA-----VGRNDTHPTTGSASPKHQKKS------KLHGPTETSSCSGAA 329 Query: 339 -----EREIQYAPLSFHKGEPQDLSGQEATNNEYSEIK 371 + E+ YA L+FH P + T+ EYSE++ Sbjct: 330 PTVEMDEELHYASLNFHGMNP-----SKDTSTEYSEVR 362 >gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo sapiens] Length = 602 Score = 181 bits (458), Expect = 1e-45 Identities = 125/295 (42%), Positives = 165/295 (55%), Gaps = 21/295 (7%) Query: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNV 143 +W +Q+ H G P+T L +R R D+GRY R E + + L ++V Sbjct: 298 SWVLQDRVLSSSHPWG-PRTLG--LELRGVRAGDSGRYTCRAEN---RLGSQQQALDLSV 351 Query: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203 PP+NL V V Q T LGN +SL VLEGQSLRLVC S+PPARLSWT T+ Sbjct: 352 QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVG 411 Query: 204 PSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGA 262 PSQPS+P VLEL + + EGEFTC AQ+ LGSQHVSL+LS+ K+ G+ LGA Sbjct: 412 PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH----WKLEHGGGLGLGA 467 Query: 263 VGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWA 322 GAG AL+ C++ V+ CRK++ + AA +D + G SQG+ E A Sbjct: 468 ALGAGVAALLAFCSCLVVFRVKICRKEARKRAA-----AEQDVPSTLGPISQGHQHECSA 522 Query: 323 DDNPRH--HGLAAHS--SGEEREIQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKI 372 + H G A ++ GEE+E+ YA LSF + + QEA + EYSEIKI Sbjct: 523 GSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 577 Score = 112 bits (281), Expect = 4e-25 Identities = 73/213 (34%), Positives = 108/213 (50%), Gaps = 25/213 (11%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 +LL LLLP+L G + YSL +Q V V EG+CV V C+ SYP D +S Sbjct: 14 LLLPLLLPVLGA-----GSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTA 68 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 +GYWF+ APVATNN + V+ TRDRF L GDP +C+L IRDA+ D Sbjct: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128 Query: 121 YFFRMEKGN-IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179 YFFR+E+G+ ++ ++ + + VT + V + + ++ GQ + Sbjct: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE---------------TLEPGQPV 173 Query: 180 RLVC----AVDSNPPARLSWTWRSLTLYPSQPS 208 ++C A P SWT +L+ ++PS Sbjct: 174 TVICVFNWAFKKCPAPSFSWTGAALSPRRTRPS 206 Score = 83.6 bits (205), Expect = 3e-16 Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 3/108 (2%) Query: 141 VNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL 200 + V P++L +++ +A GN L V +GQ LRL+CA DS PPA LSW + Sbjct: 245 LRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDR 304 Query: 201 TLYPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 L S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q Sbjct: 305 VLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352 >gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 precursor [Homo sapiens] Length = 453 Score = 159 bits (403), Expect = 3e-39 Identities = 102/237 (43%), Positives = 140/237 (59%), Gaps = 14/237 (5%) Query: 139 LSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 198 + +NV+ PQ + +++FQG A L N+SSL VLEGQ+LRL+C D NPPA LSW Sbjct: 230 IQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQG 289 Query: 199 SLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSG 257 L + SN VLEL QV +EG+FTCRAQ+ LGS +SL+L + + G+ +G Sbjct: 290 FPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPEGR----AG 345 Query: 258 VLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNL 317 +LGAV GA T LVFL C IF V++ RKK+A+P + D+ N + S S+G+ Sbjct: 346 GVLGAVWGASITTLVFLCVCFIF-RVKTRRKKAAQPVQNTDDV-----NPVMVSGSRGHQ 399 Query: 318 TESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK 374 + H A S +E+E+ YA L FHK +PQ+ + T+ EYSEIKI K Sbjct: 400 HQFQTGIVSDHPAEAGPISEDEQELHYAVLHFHKVQPQE---PKVTDTEYSEIKIHK 453 Score = 115 bits (287), Expect = 8e-26 Identities = 84/218 (38%), Positives = 109/218 (50%), Gaps = 46/218 (21%) Query: 2 LLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPV 61 +L LLLPLLW G + + + L S+TVQEG+CV V C + + Sbjct: 12 MLPLLLPLLWA-----GALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYG--- 63 Query: 62 HGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRY 121 +GYWF G D+ PVATN+P VQEETR RFHLL DP+ KNC+LSIRDAR D Y Sbjct: 64 YGYWFLEGADV----PVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAY 119 Query: 122 FFRMEKGNIKWNYKYDQLSV---------NVTDP-------PQNLTVTV----------- 154 FFR++ +K+ Y +LSV N++ P P NLT +V Sbjct: 120 FFRLKSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPI 179 Query: 155 FQGEGTASTALG----NSSSLSVL---EGQSLRLVCAV 185 F A T+LG SS L++ + S L C V Sbjct: 180 FSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQV 217 >gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] Length = 396 Score = 154 bits (388), Expect = 2e-37 Identities = 107/285 (37%), Positives = 142/285 (49%), Gaps = 38/285 (13%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 ML LLLLPLLWG G + Y L +Q SVTVQEG+CV V CSFSYP S S P Sbjct: 1 MLPLLLLPLLWG-----GSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPP 55 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 ++ YWFR G + VATNNP V+ ET+ RF LLGD Q KNC+LSI DARM D G Sbjct: 56 LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGS 115 Query: 121 YFFRMEKG-NIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLE---- 175 YFFR+E+G ++K++Y+ ++L++ V TAL + LE Sbjct: 116 YFFRVERGRDVKYSYQQNKLNLEV-------------------TALIEKPDIHFLEPLES 156 Query: 176 GQSLRLVCAV----DSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCRAQ 230 G+ RL C++ ++ PP SWT +L+ + + L L D G TC+ + Sbjct: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVK 216 Query: 231 NSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLS 275 + L Y + +S G TAL LS Sbjct: 217 RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTG----TALRILS 257 Score = 99.4 bits (246), Expect = 5e-21 Identities = 62/142 (43%), Positives = 80/142 (56%), Gaps = 13/142 (9%) Query: 139 LSVNVTDPPQNLTVTVF--QGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWT 196 + +NV+ PQNL +++F G GTA L N S+ + EGQSL L C VDSNPPA LSW Sbjct: 228 VQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWF 287 Query: 197 WRSLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ---------- 245 L PSQ S LEL + + GEFTCR Q+ LGSQH+S LS+Q Sbjct: 288 REGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVT 347 Query: 246 QEYTGKMRPVSGVLLGAVGGAG 267 ++ G V ++ GA+ GAG Sbjct: 348 EKQQGSWPLVLTLIRGALMGAG 369 >gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] Length = 551 Score = 152 bits (385), Expect = 4e-37 Identities = 104/258 (40%), Positives = 138/258 (53%), Gaps = 40/258 (15%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 ML LLLLPLLWG G + Y L +Q SVTVQEG+CV V CSFSYP S S P Sbjct: 1 MLPLLLLPLLWG-----GSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPP 55 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 ++ YWFR G + VATNNP V+ ET+ RF LLGD Q KNC+LSI DARM D G Sbjct: 56 LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGS 115 Query: 121 YFFRMEKG-NIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLE---- 175 YFFR+E+G ++K++Y+ ++L++ V TAL + LE Sbjct: 116 YFFRVERGRDVKYSYQQNKLNLEV-------------------TALIEKPDIHFLEPLES 156 Query: 176 GQSLRLVCAV----DSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCRAQ 230 G+ RL C++ ++ PP SWT +L+ + + L L D G TC+ + Sbjct: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMK 216 Query: 231 NSLGSQ-----HVSLNLS 243 G+Q V LN+S Sbjct: 217 RQ-GAQVTTERTVQLNVS 233 Score = 84.0 bits (206), Expect = 2e-16 Identities = 52/107 (48%), Positives = 68/107 (63%), Gaps = 4/107 (3%) Query: 139 LSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 198 + +NV+ PQ T+T+F+ G A L N+S L VLEGQ+LRL+C SNPPA LSW Sbjct: 228 VQLNVSYAPQ--TITIFRN-GIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQG 284 Query: 199 SLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 S L + SN +LEL +V +EG FTCRAQ+ LG + LNLS+ Sbjct: 285 SPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSV 331 Score = 69.3 bits (168), Expect = 5e-12 Identities = 65/217 (29%), Positives = 98/217 (45%), Gaps = 27/217 (12%) Query: 175 EGQSLRLVCAVDSNPPARLSWTWRSLTL----------YPSQPSNPLV---LELQVHLGD 221 E + L C+ + P L W L S + P L L L Sbjct: 345 EAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSS 404 Query: 222 EGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFI 281 + + +C+A N GSQ S+ L LQ G+ +GV+ A+GGAG AL+ + C+IF Sbjct: 405 DLKVSCKAWNIYGSQSGSV-LLLQ----GRSNLGTGVVPAALGGAGVMALLCICLCLIFF 459 Query: 282 VVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWAD---DNPRHHGLAAHSSGE 338 ++ R+K A + M D + I G+ + G+ + W D D G A E Sbjct: 460 LIVKARRKQAAGRPE----KMDDEDPIMGTITSGSRKKPWPDSPGDQASPPG-DAPPLEE 514 Query: 339 EREIQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKIPK 374 ++E+ YA LSF + + ++ QEA + EYSEIK K Sbjct: 515 QKELHYASLSFSEMKSREPKDQEAPSTTEYSEIKTSK 551 >gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo sapiens] Length = 698 Score = 132 bits (331), Expect = 7e-31 Identities = 79/162 (48%), Positives = 99/162 (61%), Gaps = 7/162 (4%) Query: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNV 143 +W +Q+ H G P+T L +R R D+GRY R E + + L ++V Sbjct: 298 SWVLQDRVLSSSHPWG-PRTLG--LELRGVRAGDSGRYTCRAEN---RLGSQQQALDLSV 351 Query: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203 PP+NL V V Q T LGN +SL VLEGQSLRLVC S+PPARLSWT T+ Sbjct: 352 QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVG 411 Query: 204 PSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 PSQPS+P VLEL + + EGEFTC AQ+ LGSQHVSL+LS+ Sbjct: 412 PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453 Score = 112 bits (281), Expect = 4e-25 Identities = 73/213 (34%), Positives = 108/213 (50%), Gaps = 25/213 (11%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 +LL LLLP+L G + YSL +Q V V EG+CV V C+ SYP D +S Sbjct: 14 LLLPLLLPVLGA-----GSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTA 68 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 +GYWF+ APVATNN + V+ TRDRF L GDP +C+L IRDA+ D Sbjct: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128 Query: 121 YFFRMEKGN-IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179 YFFR+E+G+ ++ ++ + + VT + V + + ++ GQ + Sbjct: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE---------------TLEPGQPV 173 Query: 180 RLVC----AVDSNPPARLSWTWRSLTLYPSQPS 208 ++C A P SWT +L+ ++PS Sbjct: 174 TVICVFNWAFKKCPAPSFSWTGAALSPRRTRPS 206 Score = 83.6 bits (205), Expect = 3e-16 Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 3/108 (2%) Query: 141 VNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL 200 + V P++L +++ +A GN L V +GQ LRL+CA DS PPA LSW + Sbjct: 245 LRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDR 304 Query: 201 TLYPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 L S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q Sbjct: 305 VLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352 Score = 69.3 bits (168), Expect = 5e-12 Identities = 66/216 (30%), Positives = 97/216 (44%), Gaps = 27/216 (12%) Query: 175 EGQSLRLVCAVDSNPPARLSW-----------TWRSLTLYPSQPSNPLVLELQVHLGDEG 223 E + L C+ ++P L W + S + PS L +H G Sbjct: 467 EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSS 526 Query: 224 --EFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFI 281 C+A N G+Q + S+ Q GK+ G+ LGA GAG AL+ C++ Sbjct: 527 GLRLRCKAWNVHGAQ----SGSVFQLLPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVF 582 Query: 282 VVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRH--HGLAAHS--SG 337 V+ CRK++ + AA +D + G SQG+ E A + H G A ++ G Sbjct: 583 RVKICRKEARKRAA-----AEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKG 637 Query: 338 EEREIQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKI 372 EE+E+ YA LSF + + QEA + EYSEIKI Sbjct: 638 EEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 673 >gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] Length = 697 Score = 130 bits (328), Expect = 1e-30 Identities = 77/213 (36%), Positives = 118/213 (55%), Gaps = 26/213 (12%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 +L LLL LL G + ++G+ + + +Q SV V EG+C+ V CSFSYP T S P Sbjct: 2 LLPLLLSSLLGGSQAMDGR------FWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTP 55 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 +GYWF+A + + APVATN+ + V+ TR RF L GDP NC+L IRDA+M D + Sbjct: 56 AYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQ 115 Query: 121 YFFRMEKGN-IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179 YFFR+E+G+ +++N+ D + VT Q V + + ++ GQ + Sbjct: 116 YFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPE---------------TLEPGQPV 160 Query: 180 RLVC----AVDSNPPARLSWTWRSLTLYPSQPS 208 ++C A + PP SWT +L+ ++P+ Sbjct: 161 TVICVFNWAFEECPPPSFSWTGAALSSQGTKPT 193 Score = 124 bits (311), Expect = 1e-28 Identities = 75/162 (46%), Positives = 95/162 (58%), Gaps = 7/162 (4%) Query: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNV 143 +W +Q H G + L + + D+GRY R E + + L ++V Sbjct: 287 SWVLQNRVLSSSHPWGP---RPLGLELPGVKAGDSGRYTCRAEN---RLGSQQRALDLSV 340 Query: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203 PP+NL V V Q T LGN +SL VLEGQSL LVC S+PPARLSWT R L Sbjct: 341 QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLS 400 Query: 204 PSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 PSQPS+P VLEL +V + EGEFTC A++ LGSQHVSL+LS+ Sbjct: 401 PSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442 Score = 76.6 bits (187), Expect = 3e-14 Identities = 45/110 (40%), Positives = 62/110 (56%), Gaps = 5/110 (4%) Query: 141 VNVTDPPQNLTVTVFQGEGTA--STALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 198 + V P++L +++ + A GN L +GQ LRL+CA DS PPA LSW + Sbjct: 232 LRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQ 291 Query: 199 SLTLYPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 + L S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q Sbjct: 292 NRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341 >gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 precursor [Homo sapiens] Length = 353 Score = 115 bits (287), Expect = 8e-26 Identities = 84/218 (38%), Positives = 109/218 (50%), Gaps = 46/218 (21%) Query: 2 LLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPV 61 +L LLLPLLW G + + + L S+TVQEG+CV V C + + Sbjct: 12 MLPLLLPLLWA-----GALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYG--- 63 Query: 62 HGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRY 121 +GYWF G D+ PVATN+P VQEETR RFHLL DP+ KNC+LSIRDAR D Y Sbjct: 64 YGYWFLEGADV----PVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAY 119 Query: 122 FFRMEKGNIKWNYKYDQLSV---------NVTDP-------PQNLTVTV----------- 154 FFR++ +K+ Y +LSV N++ P P NLT +V Sbjct: 120 FFRLKSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPI 179 Query: 155 FQGEGTASTALG----NSSSLSVL---EGQSLRLVCAV 185 F A T+LG SS L++ + S L C V Sbjct: 180 FSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQV 217 Score = 97.4 bits (241), Expect = 2e-20 Identities = 53/105 (50%), Positives = 69/105 (65%), Gaps = 1/105 (0%) Query: 139 LSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 198 + +NV+ PQ + +++FQG A L N+SSL VLEGQ+LRL+C D NPPA LSW Sbjct: 230 IQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQG 289 Query: 199 SLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNL 242 L + SN VLEL QV +EG+FTCRAQ+ LGS +SL+L Sbjct: 290 FPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSL 334 >gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] Length = 237 Score = 71.2 bits (173), Expect = 1e-12 Identities = 63/223 (28%), Positives = 97/223 (43%), Gaps = 43/223 (19%) Query: 176 GQSLRLVCAV----DSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCRAQ 230 G S L C+V + P SW + T + ++ VL + D G TC+ + Sbjct: 29 GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVK 88 Query: 231 NSLGSQHVSLNLSLQQEY--------------TGKMRPVSGVLLGAVGGAGATALVFLSF 276 + + L Y +GK +GV+ GA+GGAG TAL+ L Sbjct: 89 FAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCL 148 Query: 277 CVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSS 336 C+IF +V++ R+K+AR A +G D + GSAS + +S + HG SS Sbjct: 149 CLIFFIVKTHRRKAARTA-----VGRNDTHPTTGSASPKHQKKS------KLHGPTETSS 197 Query: 337 GE--------EREIQYAPLSFHKGEPQDLSGQEATNNEYSEIK 371 + E+ YA L+FH P + T+ EYSE++ Sbjct: 198 CSGAAPTVEMDEELHYASLNFHGMNP-----SKDTSTEYSEVR 235 >gi|11225258 myelin associated glycoprotein isoform a precursor [Homo sapiens] Length = 626 Score = 63.9 bits (154), Expect = 2e-10 Identities = 45/155 (29%), Positives = 66/155 (42%), Gaps = 14/155 (9%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 M+ L LPL W + S + M SS++ EG CV + C F +P + Sbjct: 1 MIFLTALPLFW----IMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFP--DELRPAV 54 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHG W+ PV + V E + R LLGD +NCTL + + G+ Sbjct: 55 VHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGK 114 Query: 121 YFFRMEKGNIKWNYKYDQLSV-------NVTDPPQ 148 Y+FR + G Y + + SV N+ PP+ Sbjct: 115 YYFRGDLGGYN-QYTFSEHSVLDIVNTPNIVVPPE 148 Score = 52.4 bits (124), Expect = 7e-07 Identities = 37/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%) Query: 153 TVFQGEGTAS-------TALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS 205 T Q EG AS + +SS+ +EG + L+C DSNPP L+W R T+ Sbjct: 224 TTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTW-MRDGTVLRE 282 Query: 206 QPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVG 264 + L+LEL +V ++G + C A+N+ G + ++ LS+ Y V+G ++ G Sbjct: 283 AVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVM--YAPWKPTVNGTMVAVEG 340 Score = 38.9 bits (89), Expect = 0.008 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ-VHLGDEGEFT 226 + ++ +EG+++ ++C+ SNP L+ L + L LEL V D+GE+ Sbjct: 332 NGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYW 391 Query: 227 CRAQNSLGSQHVSLNLSLQ 245 C A+N G + + NLS++ Sbjct: 392 CVAENQYGQRATAFNLSVE 410 >gi|18104957 myelin associated glycoprotein isoform b precursor [Homo sapiens] Length = 582 Score = 63.9 bits (154), Expect = 2e-10 Identities = 45/155 (29%), Positives = 66/155 (42%), Gaps = 14/155 (9%) Query: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60 M+ L LPL W + S + M SS++ EG CV + C F +P + Sbjct: 1 MIFLTALPLFW----IMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFP--DELRPAV 54 Query: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120 VHG W+ PV + V E + R LLGD +NCTL + + G+ Sbjct: 55 VHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGK 114 Query: 121 YFFRMEKGNIKWNYKYDQLSV-------NVTDPPQ 148 Y+FR + G Y + + SV N+ PP+ Sbjct: 115 YYFRGDLGGYN-QYTFSEHSVLDIVNTPNIVVPPE 148 Score = 52.4 bits (124), Expect = 7e-07 Identities = 37/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%) Query: 153 TVFQGEGTAS-------TALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS 205 T Q EG AS + +SS+ +EG + L+C DSNPP L+W R T+ Sbjct: 224 TTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTW-MRDGTVLRE 282 Query: 206 QPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVG 264 + L+LEL +V ++G + C A+N+ G + ++ LS+ Y V+G ++ G Sbjct: 283 AVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVM--YAPWKPTVNGTMVAVEG 340 Score = 38.9 bits (89), Expect = 0.008 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ-VHLGDEGEFT 226 + ++ +EG+++ ++C+ SNP L+ L + L LEL V D+GE+ Sbjct: 332 NGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYW 391 Query: 227 CRAQNSLGSQHVSLNLSLQ 245 C A+N G + + NLS++ Sbjct: 392 CVAENQYGQRATAFNLSVE 410 >gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens] Length = 328 Score = 61.6 bits (148), Expect = 1e-09 Identities = 61/260 (23%), Positives = 107/260 (41%), Gaps = 34/260 (13%) Query: 17 EGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDIS--- 73 E S + +S+ + V+ + G + C+F++P + P+ W RAG + Sbjct: 35 EVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHP--HRHYDGPLTAIW-RAGEPYAGPQ 91 Query: 74 -WKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRME-KGNIK 131 ++ A + RF LLG+P+ + +L + ++D RYF R+E G++ Sbjct: 92 VFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEFAGDVH 151 Query: 132 WNYKYDQ-LSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPP 190 Y+ + ++VT P+ + ++V A R +C + PP Sbjct: 152 DRYESRHGVRLHVTAAPRIVNISVLPSPAHA-----------------FRALCTAEGEPP 194 Query: 191 ARLSWTWRSL------TLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 L+W+ +L P + LV L +G +TC A NSLG S+ L Sbjct: 195 PALAWSGPALGNSLAAVRSPREGHGHLVTAELPALTHDGRYTCTAANSLGRSEASVYLFR 254 Query: 245 QQEYTGKMRPVSGVLLGAVG 264 +G +LLGA+G Sbjct: 255 FHGASG--ASTVALLLGALG 272 >gi|13489095 sialoadhesin precursor [Homo sapiens] Length = 1709 Score = 56.2 bits (134), Expect = 5e-08 Identities = 56/245 (22%), Positives = 101/245 (41%), Gaps = 35/245 (14%) Query: 21 SNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVAT 80 + + + ++ V +G C+ + C FS+P D + D + W+ D S + V + Sbjct: 16 AGQASWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVP-DGITAIWYY---DYSGQRQVVS 71 Query: 81 NNP-AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNI-KWNYKYDQ 138 ++ V+ R R +G+P+ + C L ++D + D+G Y FR E + +W+ Sbjct: 72 HSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGT 131 Query: 139 LSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCA---VDSNPPARLSW 195 L V VT+ P+ T+ +S + +LEG + C+ V RL W Sbjct: 132 L-VTVTEEPRVPTI---------------ASPVELLEGTEVDFNCSTPYVCLQEQVRLQW 175 Query: 196 ---------TWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQ 246 T+ S P+ + L + + D G R Q S+ + + LQ Sbjct: 176 QGQDPARSVTFNSQKFEPTGVGHLETLHMAMSWQDHGRI-LRCQLSVANHRAQSEIHLQV 234 Query: 247 EYTGK 251 +Y K Sbjct: 235 KYAPK 239 Score = 43.9 bits (102), Expect = 2e-04 Identities = 43/160 (26%), Positives = 66/160 (41%), Gaps = 32/160 (20%) Query: 107 TLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG 166 +L + A +DAG Y R G+ S + P LTV + T +T L Sbjct: 559 SLLLPAASSTDAGSYHCRARDGH----------SASGPSSPAVLTVLYPPRQPTFTTRL- 607 Query: 167 NSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN----------------- 209 + + G+ L+C VDS+PPARL + + S PS Sbjct: 608 DLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTK 667 Query: 210 -PLVLELQVH---LGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 P +L +++H L +EG + C A N+LG+ S + Q Sbjct: 668 APNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQ 707 Score = 43.1 bits (100), Expect = 4e-04 Identities = 43/179 (24%), Positives = 75/179 (41%), Gaps = 35/179 (19%) Query: 87 VQEETRDRFHLLGDPQTKNCTLSIRDAR--MSDAGRYFFRMEKGNIKWNYKYDQLSVNVT 144 V E T R++ G P ++ + ++R A ++ AG Y + + +S++V+ Sbjct: 922 VPEGTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVS 981 Query: 145 DPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYP 204 P+++T+T G L L+C VDS+PPA+L + Sbjct: 982 YAPRHVTLTTLMDTGPGRLGL---------------LLCRVDSDPPAQLRLLHGDRLVAS 1026 Query: 205 S-------QPSNPLV--------LELQVH---LGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 + + S+P + L L++H L DEG + C A N+LG S + Q Sbjct: 1027 TLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQ 1085 Score = 42.7 bits (99), Expect = 5e-04 Identities = 39/136 (28%), Positives = 59/136 (43%), Gaps = 21/136 (15%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTA 161 QTK L + A SDAG Y + E G ++ PP +++ +F E Sbjct: 284 QTKTGVLHLPQAAWSDAGVYTCQAENG-----------VGSLVSPP--ISLHIFMAEVQV 330 Query: 162 STALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTW-RSLTLYPSQPSNPLVLELQVHLG 220 S A +LE Q++ LVC + P+ L ++W ++ L S+ L L L Sbjct: 331 SPAG------PILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLATR-A 383 Query: 221 DEGEFTCRAQNSLGSQ 236 D G + C QN GS+ Sbjct: 384 DTGFYFCEVQNVHGSE 399 Score = 42.0 bits (97), Expect = 9e-04 Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 4/74 (5%) Query: 176 GQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPS---NPLVLELQ-VHLGDEGEFTCRAQN 231 GQ ++C VDS PPA+L+ + L S + N L LEL+ DEG ++C A++ Sbjct: 1186 GQLALVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARS 1245 Query: 232 SLGSQHVSLNLSLQ 245 LG + SL L L+ Sbjct: 1246 PLGQANTSLELRLE 1259 Score = 38.5 bits (88), Expect = 0.010 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 15/88 (17%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWR----SLTLYPSQPS----------NPLVL 213 S+ L + +G +C VDS P A L+ + +L P PS N L L Sbjct: 802 SALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKL 861 Query: 214 EL-QVHLGDEGEFTCRAQNSLGSQHVSL 240 E+ ++ LGD G + C A N LGS + SL Sbjct: 862 EVRELGLGDSGSYRCEATNVLGSSNTSL 889 Score = 34.3 bits (77), Expect = 0.19 Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 19/143 (13%) Query: 107 TLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG 166 TL + A +D G YF ++ N+ + + +SV V PP +T F + Sbjct: 374 TLRLHLATRADTGFYFCEVQ--NVHGSERSGPVSVVVNHPPLTPVLTAFLETQAGLVGIL 431 Query: 167 NSSSLS-------VLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ-VH 218 + S +S + G + + DS+ R S T S P N L LE++ + Sbjct: 432 HCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGT--------SGP-NSLRLEIRDLE 482 Query: 219 LGDEGEFTCRAQNSLGSQHVSLN 241 D GE+ C A NSLG+ +L+ Sbjct: 483 ETDSGEYKCSATNSLGNATSTLD 505 Score = 32.7 bits (73), Expect = 0.54 Identities = 41/163 (25%), Positives = 61/163 (37%), Gaps = 24/163 (14%) Query: 108 LSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGN 167 L IRD +D+G Y + T+ N T T+ A + Sbjct: 476 LEIRDLEETDSGEY------------------KCSATNSLGNATSTLDFHANAARLLI-- 515 Query: 168 SSSLSVLEGQSLRLVC--AVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEF 225 S + V+EGQ++ L C + P AR SW L+ P + L+L D G + Sbjct: 516 SPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEG-PGSSLLLP-AASSTDAGSY 573 Query: 226 TCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGA 268 CRA++ + S L Y + + L GAGA Sbjct: 574 HCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGA 616 Score = 32.0 bits (71), Expect = 0.93 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 15/74 (20%) Query: 181 LVCAVDSNPPARLSWTWRSLTLYPSQP------------SNPLVLELQVHL---GDEGEF 225 L C VDS P A L+ S + SQP ++P L + + D+GE+ Sbjct: 1552 LDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEY 1611 Query: 226 TCRAQNSLGSQHVS 239 C A N LGS S Sbjct: 1612 ICSASNVLGSASTS 1625 Score = 31.6 bits (70), Expect = 1.2 Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 22/109 (20%) Query: 89 EETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQ 148 E + R H+ P T L I A + D G Y E N Q S + Q Sbjct: 1035 EGSSPRLHVAVAPNTLR--LEIHGAMLEDEGVYI--CEASNT-----LGQASASADFDAQ 1085 Query: 149 NLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTW 197 + V V+ G +V EGQ + L C V + PA+L++TW Sbjct: 1086 AVNVQVWPGA-------------TVREGQLVNLTCLVWTTHPAQLTYTW 1121 Score = 29.3 bits (64), Expect = 6.0 Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 29/123 (23%) Query: 141 VNVTDPPQNLTVTV----FQGEGT----ASTALGNSSSLSVLEGQS-------------- 178 + VT P L V + + EG AS ALGN+S+ + GQ+ Sbjct: 663 MKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPSHTLQEG 722 Query: 179 --LRLVCAVD---SNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSL 233 L C V + PA SW +R+ L+ P + L L V D + CR Sbjct: 723 TEANLTCNVSREAAGSPANFSW-FRNGVLWAQGPLETVTL-LPVARTDAALYACRILTEA 780 Query: 234 GSQ 236 G+Q Sbjct: 781 GAQ 783 Score = 28.9 bits (63), Expect = 7.8 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 14/67 (20%) Query: 183 CAVDSNPPARLSWTWRSLTLYPSQ--------------PSNPLVLELQVHLGDEGEFTCR 228 C VDS PPA L+ + L S N L L++Q + + C Sbjct: 1367 CTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDDTYVCT 1426 Query: 229 AQNSLGS 235 AQN LGS Sbjct: 1427 AQNLLGS 1433 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 55.1 bits (131), Expect = 1e-07 Identities = 46/150 (30%), Positives = 67/150 (44%), Gaps = 10/150 (6%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTA 161 QT L + A +D+G Y R+ ++ + SV VT P + G Sbjct: 2386 QTHGSLLRLYQASPADSGEYVCRVLGSSVPL-----EASVLVTIEPAGSVPAL----GVT 2436 Query: 162 STALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLG 220 T SSS V EGQ+L L C V A+++W R +L + L L QV Sbjct: 2437 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPA 2496 Query: 221 DEGEFTCRAQNSLGSQHVSLNLSLQQEYTG 250 D GE+ CR S G+Q S+ +++QQ +G Sbjct: 2497 DSGEYVCRVVGSSGTQEASVLVTIQQRLSG 2526 Score = 49.3 bits (116), Expect = 6e-06 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEFT 226 SSS SV EGQ+L L C V + A+++W R +L P + L L QV D GE+ Sbjct: 2057 SSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYV 2116 Query: 227 CRAQNSLGSQHVSLNLSL 244 CR +N G + S+ +S+ Sbjct: 2117 CRVENGSGPKEASITVSV 2134 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEFT 226 SSS +V+EGQ+L L C V P A ++W R +L ++ L L Q+ + D GE+ Sbjct: 2636 SSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYV 2695 Query: 227 CRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGV 258 CRA N++ + S+ +S+ P S + Sbjct: 2696 CRANNNIDALEASIVISVSPSAGSPSAPGSSM 2727 Score = 46.6 bits (109), Expect = 4e-05 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 11/160 (6%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRM--EKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEG 159 QT+ L + +D+G Y R+ G + + SV VT + G Sbjct: 2772 QTRGSRLRLHHVSPADSGEYVCRVMGSSGPL-------EASVLVTIEASGSSAVHVPAPG 2824 Query: 160 TASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS-QPSNPLVLELQVH 218 A SS V EGQ+L L C V A+++W R L Q PL+ QV Sbjct: 2825 GAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 2884 Query: 219 LGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGV 258 D GE++C+ S G+ S+ ++++ G + P G+ Sbjct: 2885 PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI-PAPGL 2923 Score = 43.1 bits (100), Expect = 4e-04 Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 22/138 (15%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTA 161 Q + L I A +DAG+Y R G + ++T +TVT QG A Sbjct: 2290 QVRGSRLYIFQASPADAGQYVCRASNG----------MEASIT-----VTVTGTQGANLA 2334 Query: 162 STALGNS------SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL 215 A SS V EGQ+L L C V A+++W R +L ++ +L L Sbjct: 2335 YPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRL 2394 Query: 216 -QVHLGDEGEFTCRAQNS 232 Q D GE+ CR S Sbjct: 2395 YQASPADSGEYVCRVLGS 2412 Score = 43.1 bits (100), Expect = 4e-04 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 1/100 (1%) Query: 158 EGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-Q 216 +G A SSS S+ G +L L C V S P ++W R +L L + Q Sbjct: 2530 QGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQ 2589 Query: 217 VHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVS 256 V D GE+ C N GS+ SL +++Q + + VS Sbjct: 2590 VTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVS 2629 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/170 (25%), Positives = 70/170 (41%), Gaps = 23/170 (13%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGE--- 158 QT L + ++D+G Y R N D L ++ ++V+ G Sbjct: 2675 QTHGSHLRLHQMSVADSGEYVCRA-------NNNIDALEASIV-----ISVSPSAGSPSA 2722 Query: 159 -GTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-Q 216 G++ SSS V EG++L L C V A+++W R +L + L L Sbjct: 2723 PGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHH 2782 Query: 217 VHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGA 266 V D GE+ CR S G S+ ++++ + S V + A GGA Sbjct: 2783 VSPADSGEYVCRVMGSSGPLEASVLVTIEASGS------SAVHVPAPGGA 2826 Score = 41.6 bits (96), Expect = 0.001 Identities = 42/182 (23%), Positives = 65/182 (35%), Gaps = 35/182 (19%) Query: 67 RAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRME 126 R G D+++ + +PA+ + L N L+IR+ ++SDAG Y Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVC--- 1840 Query: 127 KGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG--NSSSLSVLEGQSLRLVCA 184 N+ Q Q GT S + + L+V GQ C+ Sbjct: 1841 ------------TGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCS 1888 Query: 185 VDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLG----------DEGEFTCRAQNSLG 234 +P L WT P L + Q+H G D+ ++ CRA +S G Sbjct: 1889 ATGSPTPTLEWT--------GGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAG 1940 Query: 235 SQ 236 Q Sbjct: 1941 QQ 1942 Score = 41.2 bits (95), Expect = 0.002 Identities = 40/156 (25%), Positives = 66/156 (42%), Gaps = 27/156 (17%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQ-NLTVTVFQG--E 158 Q L + +D+G Y R+E G+ P + ++TV+V G Sbjct: 2096 QVHGSRLRLPQVSPADSGEYVCRVENGS---------------GPKEASITVSVLHGTHS 2140 Query: 159 GTASTALGNS--------SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNP 210 G + T + S SS V EGQ+L L C V A+++W R +L ++ Sbjct: 2141 GPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHG 2200 Query: 211 LVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 +L L QV D GE+ C + G S+ ++++ Sbjct: 2201 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIE 2236 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 159 GTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ-V 217 G A +SS V EGQ+L L C V A+++W R +L ++ L L V Sbjct: 2922 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLV 2981 Query: 218 HLGDEGEFTCRAQNSLGSQ 236 D GE+ CRA + G + Sbjct: 2982 SPADSGEYVCRAASGPGPE 3000 Score = 37.0 bits (84), Expect = 0.029 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTL-YPSQPSNPLVLELQVHLGDEGEFT 226 SSS +V EGQ+L L C V A+++W R +L Q + Q D G++ Sbjct: 2251 SSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYV 2310 Query: 227 CRAQNSL 233 CRA N + Sbjct: 2311 CRASNGM 2317 Score = 35.4 bits (80), Expect = 0.084 Identities = 48/221 (21%), Positives = 76/221 (34%), Gaps = 37/221 (16%) Query: 26 YSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAW 85 Y+ T+ +VQ G V ++C + P+ W R G+ + +A Sbjct: 3300 YATTVPEHASVQAGETVQLQCLAH-------GTPPLTFQWSRVGSSLPGRATA------- 3345 Query: 86 AVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTD 145 +N L A D+GRY R+ + + QL V Sbjct: 3346 ------------------RNELLHFERAAPEDSGRYRCRVTN-KVGSAEAFAQLLVQ--G 3384 Query: 146 PPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS 205 PP +L T T + + + G S+ CAV S+ +L W L P Sbjct: 3385 PPGSLPATSIPAGSTPTVQVTPQLETKSI-GASVEFHCAVPSDRGTQLRWFKEGGQLPPG 3443 Query: 206 QPSNPLVLELQ-VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 VL +Q + +G + C+A G S L +Q Sbjct: 3444 HSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQ 3484 Score = 35.0 bits (79), Expect = 0.11 Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 3/110 (2%) Query: 138 QLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTW 197 Q N T P + T+ + A SV G++++L C PP W+ Sbjct: 3275 QYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWS- 3333 Query: 198 RSLTLYPSQPS--NPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 R + P + + N L+ + D G + CR N +GS L +Q Sbjct: 3334 RVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3383 Score = 31.6 bits (70), Expect = 1.2 Identities = 38/160 (23%), Positives = 60/160 (37%), Gaps = 37/160 (23%) Query: 129 NIKWNYKYDQLSVNVTDPPQNLTVTVF----QGEGT----ASTALGNSSSL--------- 171 +++W + +L NV P +T+ GT AS A G + S+ Sbjct: 3053 SLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPP 3112 Query: 172 --SVLE--------GQSLRLVCAVDSNPPARLSWTWRSLT-------LYPSQPSNPLVLE 214 SVL G+++ L C P + WT S T Y S+ ++ Sbjct: 3113 TVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQI 3172 Query: 215 LQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRP 254 D G + C AQN+LG+ + + + TG M P Sbjct: 3173 SSAKPSDAGTYVCLAQNALGTAQKQVEVIVD---TGAMAP 3209 Score = 30.8 bits (68), Expect = 2.1 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS-QPSNPLVLELQVHLGDEGEFT 226 +S +V+ G ++ C +P +++W+ L P S +V V L D G++ Sbjct: 3495 TSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYR 3554 Query: 227 CRAQNSLGSQHVSLNLSLQ 245 C A N+ G+ + L +Q Sbjct: 3555 CTATNAAGTTQSHVLLLVQ 3573 Score = 30.0 bits (66), Expect = 3.5 Identities = 17/72 (23%), Positives = 30/72 (41%), Gaps = 7/72 (9%) Query: 170 SLSVLEGQSLRLVCAVDSNPPARLSW--TWRSLTLYP-----SQPSNPLVLELQVHLGDE 222 S+ GQ++ C P ++W W + +P S+ ++ V D+ Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 474 Query: 223 GEFTCRAQNSLG 234 G +TC A N+ G Sbjct: 475 GAYTCEAMNARG 486 Score = 29.3 bits (64), Expect = 6.0 Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 14/107 (13%) Query: 146 PPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPA-RLSWTWRSLTLYP 204 P + +TVTV + S SV G + +C S PA L WT P Sbjct: 1767 PSKPITVTVEE-----------QRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLP 1815 Query: 205 SQPS--NPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYT 249 ++ N ++ V L D G + C N + L +Q T Sbjct: 1816 TRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGT 1862 >gi|109150416 peroxidasin [Homo sapiens] Length = 1479 Score = 54.7 bits (130), Expect = 1e-07 Identities = 62/224 (27%), Positives = 98/224 (43%), Gaps = 37/224 (16%) Query: 32 SSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRA-GN---DISWKAPVATNNPAWAV 87 +++T +E C R + S P D+ S + RA GN +I W + NN + Sbjct: 234 ATITPEELNCERPRIT-SEPQDADVTSGNTVYFTCRAEGNPKPEIIW---LRNNNE---L 286 Query: 88 QEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPP 147 +T R +LL D TL I++ + +D G Y + N+ K ++++ P Sbjct: 287 SMKTDSRLNLLDDG-----TLMIQNTQETDQGIY--QCMAKNVAGEVKTQEVTLRYFGSP 339 Query: 148 QNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ- 206 T V Q + T VL G+S+ L C+ +PP R+SWT T P Sbjct: 340 ARPTF-VIQPQNT-----------EVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDP 387 Query: 207 -----PSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 PS L ++ V GD GE+ C A N++ S H + + +Q Sbjct: 388 RVNITPSGGLYIQ-NVVQGDSGEYACSATNNIDSVHATAFIIVQ 430 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 8/83 (9%) Query: 173 VLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ------VHLGDEGEFT 226 V+EGQ++ C NPP ++WT L S LVL V L D+G++ Sbjct: 444 VIEGQTVDFQCEAKGNPPPVIAWTKGGSQL--SVDRRHLVLSSGTLRISGVALHDQGQYE 501 Query: 227 CRAQNSLGSQHVSLNLSLQQEYT 249 C+A N +GSQ V +L++Q T Sbjct: 502 CQAVNIIGSQKVVAHLTVQPRVT 524 Score = 32.7 bits (73), Expect = 0.54 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 6/81 (7%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS-----QPSNPLVLELQVHLGDEG 223 S +V G +++L C+ P ++W + + S P L + V D G Sbjct: 532 SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTIN-DVGPADAG 590 Query: 224 EFTCRAQNSLGSQHVSLNLSL 244 + C A+N++GS VS+ LS+ Sbjct: 591 RYECVARNTIGSASVSMVLSV 611 >gi|21361429 V-set and immunoglobulin domain containing 2 [Homo sapiens] Length = 327 Score = 52.4 bits (124), Expect = 7e-07 Identities = 66/295 (22%), Positives = 119/295 (40%), Gaps = 41/295 (13%) Query: 39 GMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVA--TNNPAWAVQEETRDRFH 96 G + C++S V DS + + + G IS P+ TN + +++ R Sbjct: 38 GKTAELTCTYSTSVG---DSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSK-RVS 93 Query: 97 LLGDPQTKN-CTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVF 155 LL +P T TL + D SD G Y ++ + +++ V PP N + Sbjct: 94 LLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQ- 152 Query: 156 QGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLE- 214 + T++G S++L C+ P + + W L +P+ +V + Sbjct: 153 ----SGQTSVGGSTALR----------CSSSEGAPKPV-YNWVRLGTFPTPSPGSMVQDE 197 Query: 215 -------LQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAG 267 + L G + C A N +GS L LS+ + G+ V+G L+G + G Sbjct: 198 VSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGR---VAGALIGVL--LG 252 Query: 268 ATALVFLSFCVI-FIVVRSCRKKSARPAADVGD----IGMKDANTIRGSASQGNL 317 L +FC++ F R + K +D+ + G+ + +R +S+G L Sbjct: 253 VLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAPGISEHTCMRADSSKGFL 307 >gi|62988340 leucine rich repeat containing 22 [Homo sapiens] Length = 550 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 9/87 (10%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWT-----WRSLTLYPSQPSNPLVL-ELQV---H 218 S+++++ GQ++ L C ++P ++WT WR + S L EL + H Sbjct: 259 SANITIRAGQNVTLRCLAQASPSPSIAWTYPLSMWREFDVLTSSTGEDTALSELAIPAAH 318 Query: 219 LGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 L D G +TC A NS+G ++ ++L +Q Sbjct: 319 LVDSGNYTCMASNSIGKSNLVISLHVQ 345 >gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1 [Homo sapiens] Length = 1093 Score = 47.8 bits (112), Expect = 2e-05 Identities = 62/255 (24%), Positives = 104/255 (40%), Gaps = 40/255 (15%) Query: 72 ISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEK--GN 129 I+W+ T+ PA R H++ D I D ++ DAG Y + G+ Sbjct: 630 IAWQKDGGTDFPA-----ARERRMHVMPDDDV----FFITDVKIDDAGVYSCTAQNSAGS 680 Query: 130 IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNP 189 I N T+TV + T S + + V G+++ L C NP Sbjct: 681 IS----------------ANATLTVLE---TPSLVVPLEDRV-VSVGETVALQCKATGNP 720 Query: 190 PARLSWTW--RSLTL---YPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 P R++W R L+L + P N L++ V D G +TC N+LG++ LS+ Sbjct: 721 PPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780 Query: 245 QQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKD 304 + G +G A +++V S + I+ ++ RKKS + D + Sbjct: 781 LPAAGCRK---DGTTVGIFTIAVVSSIVLTSLVWVCIIYQT-RKKSEEYSVTNTDETVVP 836 Query: 305 ANTIRGSASQGNLTE 319 + +SQG L++ Sbjct: 837 PDVPSYLSSQGTLSD 851 Score = 35.8 bits (81), Expect = 0.064 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 10/73 (13%) Query: 180 RLVCAVDSNPPARLSWTWRSLTLYPS--------QPSNPLVLELQVHLGDEGEFTCRAQN 231 RL CA +P +++W T +P+ P + + V + D G ++C AQN Sbjct: 617 RLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQN 676 Query: 232 SLGSQHVSLNLSL 244 S GS +S N +L Sbjct: 677 SAGS--ISANATL 687 >gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] Length = 600 Score = 47.0 bits (110), Expect = 3e-05 Identities = 46/210 (21%), Positives = 81/210 (38%), Gaps = 45/210 (21%) Query: 107 TLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG 166 TL+++ R DAG+Y R + + ++++ V PP + Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGER--EVTLTVNGPP----------------IIS 423 Query: 167 NSSSLSVLEGQSLRLVCAVDSNPPA-RLSWTWRSLTLYPSQPS--------------NPL 211 ++ + L G+ ++ C + S PP R++W+W+ L + L Sbjct: 424 STQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTL 483 Query: 212 VLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSG---------VLLGA 262 + V + + C A NS GS + L +E +M+ +G V++G Sbjct: 484 TISNIVRADFQTIYNCTAWNSFGSDTEIIRL---KEQGSEMKSGAGLEAESVPMAVIIGV 540 Query: 263 VGGAGATALVFLSFCVIFIVVRSCRKKSAR 292 GAG LV ++ V F RS R R Sbjct: 541 AVGAGVAFLVLMATIVAFCCARSQRSTGGR 570 >gi|15147240 brother of CDO [Homo sapiens] Length = 1114 Score = 45.8 bits (107), Expect = 6e-05 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP---SNPLVLELQVHLGDEGEF 225 S L + GQS +L C V NPP + W ++ L SQ S + L + DEG + Sbjct: 330 SQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALRVLSMGPEDEGVY 389 Query: 226 TCRAQNSLGSQHVSLNL 242 C A+N +GS H + L Sbjct: 390 QCMAENEVGSAHAVVQL 406 Score = 33.1 bits (74), Expect = 0.42 Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHL---GDEGE 224 + ++ V +GQSL L C PP R++W ++ + L+ L + D G Sbjct: 237 AQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSNLLIDTTSEEDSGT 296 Query: 225 FTCRAQNSLG 234 + C A N +G Sbjct: 297 YRCMADNGVG 306 >gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] Length = 778 Score = 45.4 bits (106), Expect = 8e-05 Identities = 45/205 (21%), Positives = 80/205 (39%), Gaps = 45/205 (21%) Query: 107 TLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG 166 TL+++ R DAG+Y R + + ++++ V PP + Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGER--EVTLTVNGPP----------------IIS 423 Query: 167 NSSSLSVLEGQSLRLVCAVDSNPPA-RLSWTWRSLTLYPSQPS--------------NPL 211 ++ + L G+ ++ C + S PP R++W+W+ L + L Sbjct: 424 STQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTL 483 Query: 212 VLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSG---------VLLGA 262 + V + + C A NS GS + L +E +M+ +G V++G Sbjct: 484 TISNIVRADFQTIYNCTAWNSFGSDTEIIRL---KEQGSEMKSGAGLEAESVPMAVIIGV 540 Query: 263 VGGAGATALVFLSFCVIFIVVRSCR 287 GAG LV ++ V F RS R Sbjct: 541 AVGAGVAFLVLMATIVAFCCARSQR 565 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/160 (21%), Positives = 78/160 (48%), Gaps = 15/160 (9%) Query: 87 VQEETRDRFHLLGDPQT-KNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTD 145 +QE+ D+++ + T +N ++ D +M +Y FR+ N+K +Y + S+ + Sbjct: 29380 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQ--KYSFRVAAVNVKGMSEYSE-SIAEIE 29436 Query: 146 PPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTL--- 202 P + + + + A ++++ G SLRL+ +V PP ++W+ + + L Sbjct: 29437 PVERIEIPDLE------LADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASR 29490 Query: 203 --YPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSL 240 + S L++ +V+ D G++T A+N G + ++ Sbjct: 29491 AIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATV 29530 Score = 43.5 bits (101), Expect = 3e-04 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 170 SLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP-------SNPLVLELQVHLGDE 222 S+ V+ G+S C V P R++W+ + + P + P + L+V GD Sbjct: 6279 SIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDS 6338 Query: 223 GEFTCRAQNSLGSQHVSLNLSLQQ 246 G++TC+A N +G S LS+++ Sbjct: 6339 GQYTCQATNDVGKDMCSAQLSVKE 6362 Score = 42.0 bits (97), Expect = 9e-04 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 9/90 (10%) Query: 175 EGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP------SNPLVLEL-QVHLGDEGEFTC 227 +G + +L C V PP +++W + S + VL L V + D GE+ C Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMC 4372 Query: 228 RAQNSLGSQHVSLNLSLQQE--YTGKMRPV 255 AQN GS H S + +++ +T + +P+ Sbjct: 4373 EAQNEAGSDHCSSIVIVKESPYFTKEFKPI 4402 Score = 42.0 bits (97), Expect = 9e-04 Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 25/139 (17%) Query: 104 KNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTAST 163 K C L I ++ DAG+Y +E + V+ +PP +T Sbjct: 6039 KTCILEILNSTKRDAGQYSCEIEN---EAGRDVCGALVSTLEPPYFVT------------ 6083 Query: 164 ALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP------SNPLVLEL-Q 216 L G S+ L C V P +SW L P+ +N L + Sbjct: 6084 ---ELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNK 6140 Query: 217 VHLGDEGEFTCRAQNSLGS 235 V++ D GE+TC+A+NS+G+ Sbjct: 6141 VNINDSGEYTCKAENSIGT 6159 Score = 41.6 bits (96), Expect = 0.001 Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 25/162 (15%) Query: 107 TLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG 166 +L I ++ D G Y K + +Y +S T LTVT E T L Sbjct: 3512 SLEILRTQVVDCGEY-------TCKASNEYGSVSCTAT-----LTVT----EAYPPTFLS 3555 Query: 167 NSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS------QPSNPLVLELQ-VHL 219 SL+ G++ + +C V P W L PS N +LEL + + Sbjct: 3556 RPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTI 3615 Query: 220 GDEGEFTCRAQNSLGSQHVSLNLSL--QQEYTGKMRPVSGVL 259 D G ++C+A N G+ L + + + ++ PV + Sbjct: 3616 QDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAI 3657 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ------PSNPLVLELQ-VHLGDEG 223 ++V EG+ ++L C V + P R+ W + PS S VLEL+ V D G Sbjct: 8355 VTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 8414 Query: 224 EFTCRAQNSLGSQHVSLNLSLQQE 247 ++ C+A N GS ++++ + Sbjct: 8415 DYVCKASNVAGSDTTKSKVTIKDK 8438 Score = 40.4 bits (93), Expect = 0.003 Identities = 43/203 (21%), Positives = 74/203 (36%), Gaps = 48/203 (23%) Query: 52 VDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIR 111 V+ + + D V +W++ G +I+++ + V+ F I Sbjct: 3166 VEFEVNEDDVDAHWYKDGIEINFQVQ---ERHKYVVERRIHRMF--------------IS 3208 Query: 112 DARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSL 171 + R SDAG Y F + N L VN +PPQ L + Sbjct: 3209 ETRQSDAGEYTFVAGR-----NRSSVTLYVNAPEPPQ---------------VLQELQPV 3248 Query: 172 SVLEGQSLRLVCAVDSNPPARLSWT---------WRSLTLYPSQPSNPLVLELQVHLGDE 222 +V G+ R + P ++SW ++ L+ Q L++E D Sbjct: 3249 TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPE--DA 3306 Query: 223 GEFTCRAQNSLGSQHVSLNLSLQ 245 +TC A+N G S +LS++ Sbjct: 3307 AVYTCEAKNDYGVATTSASLSVE 3329 Score = 39.7 bits (91), Expect = 0.004 Identities = 37/151 (24%), Positives = 61/151 (40%), Gaps = 25/151 (16%) Query: 104 KNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTAST 163 K+ L I + + DAG+Y +E + K + L + +PP + Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQIL---ILEPPYFVK------------ 7965 Query: 164 ALGNSSSLSVLEGQSLRLVCAVDSNPPARLSW-----TWRSLTLYPSQPSNPLVLEL--Q 216 + V G S L C + P +SW R T Y N + + Q Sbjct: 7966 ---QLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQ 8022 Query: 217 VHLGDEGEFTCRAQNSLGSQHVSLNLSLQQE 247 V + D GE+ C+A+NS+G S L++Q++ Sbjct: 8023 VDINDSGEYICKAENSVGEVSASTFLTVQEQ 8053 Score = 39.3 bits (90), Expect = 0.006 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Query: 172 SVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLE-------LQVHLGDEGE 224 SV+ G + RL C + + P R+SW + S +E ++V + D G Sbjct: 4124 SVVNG-TCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGN 4182 Query: 225 FTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVS 256 FTCRA NS+GS+ S L +Q+ + +P S Sbjct: 4183 FTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 4214 Score = 39.3 bits (90), Expect = 0.006 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 7/93 (7%) Query: 161 ASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ---- 216 A+ L S++V EG+S R C D P ++W + L S + + Sbjct: 32560 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFE 32619 Query: 217 ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQQ 246 V DEG ++ +NS G Q L++Q+ Sbjct: 32620 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 32652 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP----SNPLVLELQV---HLGDEG 223 L V G + C + S P R W +Y S S+ + L++ + D G Sbjct: 3465 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCG 3524 Query: 224 EFTCRAQNSLGSQHVSLNLSLQQEY 248 E+TC+A N GS + L++ + Y Sbjct: 3525 EYTCKASNEYGSVSCTATLTVTEAY 3549 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 10/97 (10%) Query: 175 EGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN-------PLVLELQVHLGDEGEFTC 227 +G+S++L C + +P ++SW L+ S N L+ + D G++ C Sbjct: 6378 QGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYIC 6437 Query: 228 RAQNSLGSQHVSLNLSLQQE--YTGKMRPVSGVLLGA 262 A N +G S L+++ +T K PV G L G+ Sbjct: 6438 EAHNGVGDASCSTALTVKAPPVFTQKPSPV-GALKGS 6473 Score = 38.1 bits (87), Expect = 0.013 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 9/68 (13%) Query: 176 GQSLRLVCAVDSNPPARLSW-----TWRSLTLYPSQPSN---PLVLELQVHLGDEGEFTC 227 G+ L C VD P R+SW RS Y Q N LV+ H D GE++C Sbjct: 7034 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDH-SDVGEYSC 7092 Query: 228 RAQNSLGS 235 +A NS+G+ Sbjct: 7093 KADNSVGA 7100 Score = 37.7 bits (86), Expect = 0.017 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 9/98 (9%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSW-----TWRSLTLYPSQPSNPL--VLELQVHLGDEG 223 + L+G + L C + PP +SW RS Y N L + L V D G Sbjct: 7408 IETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIG 7467 Query: 224 EFTCRAQNSLGSQHV--SLNLSLQQEYTGKMRPVSGVL 259 E+ C+A N +GS S+ L + K+ +S V+ Sbjct: 7468 EYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVV 7505 Score = 37.4 bits (85), Expect = 0.022 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 7/93 (7%) Query: 160 TASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS-------QPSNPLV 212 T T + +++V+EG+S+ L C + P ++W + S Q + Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000 Query: 213 LELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 + + D G FTC A N G+ S L++Q Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033 Score = 37.0 bits (84), Expect = 0.029 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 9/94 (9%) Query: 170 SLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLE-------LQVHLGDE 222 S+ + G+S C V P +++W + + P ++E L+V GD Sbjct: 7220 SVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDA 7279 Query: 223 GEFTCRAQNSLGSQHVSLNLSLQQ--EYTGKMRP 254 G++TC A N G S L +Q+ + K+ P Sbjct: 7280 GQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEP 7313 Score = 36.6 bits (83), Expect = 0.038 Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 28/154 (18%) Query: 102 QTKNCTLSIRDARMSDAGRYFFRM--EKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEG 159 + K TL I A++ D+G Y E G+ + +V V +PP + Sbjct: 3695 EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCS-----ATVTVREPPSFVKKV------ 3743 Query: 160 TASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP------SNPLVL 213 S +L G+S RL C + +P +++W + L S ++ +L Sbjct: 3744 --------DPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAIL 3795 Query: 214 EL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQ 246 ++ V + D G ++C A N +GS S + +++ Sbjct: 3796 DITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE 3829 Score = 36.6 bits (83), Expect = 0.038 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Query: 170 SLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN----PLVLEL---QVHLGDE 222 S+ VL G SL + PP ++ W S L P + N V EL +V + Sbjct: 6842 SVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLES 6901 Query: 223 GEFTCRAQNSLGSQHVSLNLSLQQEYT 249 G+++C N GS + +L +++ T Sbjct: 6902 GDYSCLVTNDAGSASCTTHLFVKEPAT 6928 Score = 36.2 bits (82), Expect = 0.049 Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 7/78 (8%) Query: 176 GQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHL-------GDEGEFTCR 228 G+S C V P ++SW S + LE HL GD G++TC Sbjct: 8167 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCY 8226 Query: 229 AQNSLGSQHVSLNLSLQQ 246 A N +G + L++++ Sbjct: 8227 AVNEVGKDSCTAQLNIKE 8244 Score = 34.7 bits (78), Expect = 0.14 Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 28/163 (17%) Query: 104 KNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTD---PPQNLTVTVFQGEGT 160 K +L I A MSD G Y F ++ K N +SV+V+D PP Sbjct: 6698 KVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT---VSVHVSDRIVPP------------- 6741 Query: 161 ASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYP------SQPSNPLVLE 214 + + ++ + G S+ L C V + P + W + S N L Sbjct: 6742 --SFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 6799 Query: 215 LQV-HLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVS 256 L + D G +TC A N GS S L++Q+ + + P S Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDS 6842 Score = 34.7 bits (78), Expect = 0.14 Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 7/75 (9%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ------PSNPLVLEL-QVHLG 220 S ++ EG S +L V + P ++W ++ + P+ +N LVL++ + + Sbjct: 8256 SETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMN 8315 Query: 221 DEGEFTCRAQNSLGS 235 D G +TC+ N GS Sbjct: 8316 DAGLYTCKVSNDAGS 8330 Score = 34.3 bits (77), Expect = 0.19 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%) Query: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203 ++P +T+ ++ S L+V G ++ L V P +SW L Sbjct: 19278 SEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLK 19337 Query: 204 PSQ------PSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 P++ N LEL V+ D G++T A+NS GS+ ++ L + Sbjct: 19338 PAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 19385 Score = 33.5 bits (75), Expect = 0.32 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 174 LEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLE----LQVHL---GDEGEFT 226 L G S+ + C V +PP +SW + + + + L V++ D G++T Sbjct: 7694 LSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYT 7753 Query: 227 CRAQNSLGSQHVSLNLSLQQEYTGKMRP 254 C A N GS S L++++ + +P Sbjct: 7754 CIATNMAGSDECSAPLTVREPPSFVQKP 7781 Score = 33.1 bits (74), Expect = 0.42 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 18/125 (14%) Query: 157 GEGTASTALG---------NSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTL----- 202 G+ + STAL S + L+G + L C + PP + W + Sbjct: 6444 GDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKK 6503 Query: 203 --YPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQ--EYTGKMRPVSGV 258 S+ + + L + D GE+ C+A N +GS S ++ ++ + K+ S + Sbjct: 6504 FKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL 6563 Query: 259 LLGAV 263 + AV Sbjct: 6564 IGDAV 6568 Score = 32.7 bits (73), Expect = 0.54 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHL-------GDEG 223 + VL+ + L+ V PP ++W + L + + + V L D G Sbjct: 4402 IEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAG 4461 Query: 224 EFTCRAQNSLGSQHVSLNLSLQQ 246 E+ CR N +GS S ++L++ Sbjct: 4462 EYQCRVTNEVGSSICSARVTLRE 4484 Score = 32.7 bits (73), Expect = 0.54 Identities = 23/100 (23%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 176 GQSLRLVCAVDSNPPARLSWTWRSL------TLYPSQPSNPLVLE-LQVHLGDEGEFTCR 228 G + L C ++ + P ++ W + L S N L+ LQ L G+++C Sbjct: 6189 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCS 6248 Query: 229 AQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGA 268 A N LG+ S L+ ++ + V + + G A Sbjct: 6249 ASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESA 6288 Score = 32.7 bits (73), Expect = 0.54 Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN----PLVLELQ---VHLGDEG 223 + VL G ++ V PP +SW S L P N V EL+ V G Sbjct: 7784 MDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSG 7843 Query: 224 EFTCRAQNSLGSQHVSLNLSLQ 245 E+TC N G + +L ++ Sbjct: 7844 EYTCIVSNEAGKASCTTHLYIK 7865 Score = 32.3 bits (72), Expect = 0.71 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%) Query: 175 EGQSLRLVCAVDSNPPARLSWTWRSLTLYPS------QPSNPLVLEL-QVHLGDEGEFTC 227 EGQ R C V S ++SW + + PS Q + LE+ + + DEG +T Sbjct: 3358 EGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416 Query: 228 RAQNSLGSQHVSLNLSLQ 245 A N++G + NLSL+ Sbjct: 3417 VASNAVGQVSSTANLSLE 3434 Score = 32.3 bits (72), Expect = 0.71 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 7/83 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSW-----TWRSLTLYPSQPSN--PLVLELQVHLGDEG 223 + L+ + L C + PP + W RS Y N + L V D G Sbjct: 5526 VETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIG 5585 Query: 224 EFTCRAQNSLGSQHVSLNLSLQQ 246 E+ C+AQN +GS + L++ Sbjct: 5586 EYHCKAQNEVGSDTCVCTVKLKE 5608 Score = 32.3 bits (72), Expect = 0.71 Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 25/145 (17%) Query: 107 TLSIRDARMSDAG--RYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTA 164 TL+I+ A D G + ++G +K Y LS ++D P Sbjct: 33093 TLTIKQASHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDAP---------------AF 33136 Query: 165 LGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL------TLYPSQPSNPLVLELQ-V 217 + S ++ EGQ++ C + P + W +L + S+ N LE++ Sbjct: 33137 ISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNA 33196 Query: 218 HLGDEGEFTCRAQNSLGSQHVSLNL 242 + D G++T +A+N G + +L Sbjct: 33197 SVSDSGKYTIKAKNFRGQCSATASL 33221 Score = 32.0 bits (71), Expect = 0.93 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 7/85 (8%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP-------SNPLVLELQVHLGD 221 +S V G S RL C + +P R+ W L S S ++ + D Sbjct: 5431 ASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTED 5490 Query: 222 EGEFTCRAQNSLGSQHVSLNLSLQQ 246 G+F C AQN GS S + +++ Sbjct: 5491 SGDFICEAQNPAGSTSCSTKVIVKE 5515 Score = 31.6 bits (70), Expect = 1.2 Identities = 20/89 (22%), Positives = 40/89 (44%), Gaps = 7/89 (7%) Query: 173 VLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP------SNPLVLELQ-VHLGDEGEF 225 V + + R C + +P ++ W + S + VLE+ + + D G++ Sbjct: 7317 VKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDY 7376 Query: 226 TCRAQNSLGSQHVSLNLSLQQEYTGKMRP 254 TC A N+ GS S +L +++ + +P Sbjct: 7377 TCEAHNAAGSASSSTSLKVKEPPIFRKKP 7405 Score = 31.2 bits (69), Expect = 1.6 Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 12/104 (11%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ------PSNPLVLELQ-VHLG 220 + S+ V E + L C V P ++ W + PS+ +N +Q V Sbjct: 5147 AKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQ 5206 Query: 221 DEGEFTCRAQNSLGSQHVS-----LNLSLQQEYTGKMRPVSGVL 259 D G++T + +N GS L+ ++ +T K+ + VL Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL 5250 Score = 31.2 bits (69), Expect = 1.6 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN----PLVLELQ---VHLGDEG 223 L VL G+++ + PP +++W + L N V EL+ + + G Sbjct: 5902 LEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSG 5961 Query: 224 EFTCRAQNSLGSQHVSLNLSLQQ 246 E+TC N+ G + L +++ Sbjct: 5962 EYTCVVSNNAGQASCTTRLFVKE 5984 Score = 30.8 bits (68), Expect = 2.1 Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 9/93 (9%) Query: 172 SVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHL-------GDEGE 224 S+ +G+ L L PP ++W + + PSQ N E L D G+ Sbjct: 7878 SIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQ 7937 Query: 225 FTCRAQNSLGSQHVSLNLSLQQE--YTGKMRPV 255 + C +N+ G S + + + + ++ PV Sbjct: 7938 YNCYIENASGKDSCSAQILILEPPYFVKQLEPV 7970 Score = 30.4 bits (67), Expect = 2.7 Identities = 38/195 (19%), Positives = 68/195 (34%), Gaps = 51/195 (26%) Query: 59 DPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDA 118 + V G W + G ++ + DR H++ D Q+ L I D DA Sbjct: 2382 ESVEGVWMKDGQEV-----------------QPSDRVHIVIDKQSH--MLLIEDMTKEDA 2422 Query: 119 GRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQS 178 G Y F + + + + SV+V P ++ ++V+EG Sbjct: 2423 GNYSFTIPALGLSTSGRVSVYSVDVITPLKD---------------------VNVIEGTK 2461 Query: 179 LRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLV-------LELQVHLGDEGEFTCRAQN 231 L C V + W + P +V + + H DEG + + Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KL 2517 Query: 232 SLGSQHVSLNLSLQQ 246 +G + NLS+++ Sbjct: 2518 IVGRVETNCNLSVEK 2532 Score = 30.4 bits (67), Expect = 2.7 Identities = 29/123 (23%), Positives = 43/123 (34%), Gaps = 27/123 (21%) Query: 34 VTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRD 93 VT++EG + C FS P V WFR G + P + E Sbjct: 8754 VTLKEGQTCTMTCQFSVP--------NVKSEWFRNGRILK---------PQGRHKTEVEH 8796 Query: 94 RFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVT 153 + H L+I D R D G+Y + E + + + T QN+ V+ Sbjct: 8797 KVH----------KLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVS 8846 Query: 154 VFQ 156 Q Sbjct: 8847 EHQ 8849 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/86 (19%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN---------PLVLELQVHL 219 S +S+ EG+ L + CA P ++W+ ++ + ++ + V Sbjct: 33336 SDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQK 33395 Query: 220 GDEGEFTCRAQNSLGSQHVSLNLSLQ 245 D G +T N GS ++N+ ++ Sbjct: 33396 QDGGLYTLSLGNEFGSDSATVNIHIR 33421 Score = 30.0 bits (66), Expect = 3.5 Identities = 19/78 (24%), Positives = 29/78 (37%), Gaps = 21/78 (26%) Query: 108 LSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGN 167 L I++A + DAG Y R+ K +L+ PQN Sbjct: 12519 LVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQN------------------ 12560 Query: 168 SSSLSVLEGQSLRLVCAV 185 L +LEG+ VC++ Sbjct: 12561 ---LEILEGEKAEFVCSI 12575 Score = 29.6 bits (65), Expect = 4.6 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 20/131 (15%) Query: 115 MSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTAST---ALGNSSSL 171 +++ +Y FR+ N K V++P + +T Q T + ++ Sbjct: 29699 LNEGEQYLFRIRAQNEK----------GVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI 29748 Query: 172 SVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ----PSNPLVLELQVH---LGDEGE 224 V G+ + LV + PP SW + L S+ ++ V +L + + D GE Sbjct: 29749 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 29808 Query: 225 FTCRAQNSLGS 235 +T +N G+ Sbjct: 29809 YTLELKNVTGT 29819 Score = 29.3 bits (64), Expect = 6.0 Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 7/80 (8%) Query: 174 LEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP------SNPLVLEL-QVHLGDEGEFT 226 ++G + L C V + P + W + S+ N LE+ Q+ D G +T Sbjct: 4687 IKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYT 4746 Query: 227 CRAQNSLGSQHVSLNLSLQQ 246 C A N G S +L++++ Sbjct: 4747 CSATNKAGHNQCSGHLTVKE 4766 Score = 29.3 bits (64), Expect = 6.0 Identities = 22/100 (22%), Positives = 42/100 (42%), Gaps = 9/100 (9%) Query: 168 SSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLE----LQV---HLG 220 S L + GQS C + P R+SW + Q ++ Q+ + Sbjct: 4868 SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVE 4927 Query: 221 DEGEFTCRAQNSLGSQHVSLNLSLQQ--EYTGKMRPVSGV 258 + G + C A+N G+ S+ L +++ + +++PV V Sbjct: 4928 NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVV 4967 Score = 29.3 bits (64), Expect = 6.0 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPL-VLEL------QVHLGD 221 SS SV GQ L++ + P ++WT L L + N L+L + H D Sbjct: 23237 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDD 23296 Query: 222 EGEFTCRAQNSLGSQHVSLNL 242 G++ N +G + S+ + Sbjct: 23297 GGQYGITVANVVGQKTASIEI 23317 Score = 28.9 bits (63), Expect = 7.8 Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 221 DEGEFTCRAQNSLGSQHVSLNLSLQQE 247 D G TCRA N G+ H S L ++ E Sbjct: 1771 DSGIITCRATNKYGTDHTSATLIVKDE 1797 Score = 28.9 bits (63), Expect = 7.8 Identities = 43/197 (21%), Positives = 69/197 (35%), Gaps = 44/197 (22%) Query: 60 PVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAG 119 P+ WF+ G +I+ DR+ + T +L I M+DAG Sbjct: 4141 PMRVSWFKDGKEIA-----------------ASDRYRIAFVEGT--ASLEIIRVDMNDAG 4181 Query: 120 RYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179 + R K ++ V +PP +T S VL G ++ Sbjct: 4182 NFTCRATNSV---GSKDSSGALIVQEPPSFVT---------------KPGSKDVLPGSAV 4223 Query: 180 RLVCAVDSNPPARLSWTWRSLTL------YPSQPSNPLVLELQ-VHLGDEGEFTCRAQNS 232 L + P + W + L Y ++ + LEL V D G +TC+ N Sbjct: 4224 CLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNV 4283 Query: 233 LGSQHVSLNLSLQQEYT 249 G S NL +++ T Sbjct: 4284 AGGVECSANLFVKEPAT 4300 Score = 28.9 bits (63), Expect = 7.8 Identities = 31/149 (20%), Positives = 56/149 (37%), Gaps = 29/149 (19%) Query: 107 TLSIRDARMSDAGRYFF--RMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTA 164 T I AR+ ++G Y R + G + + + V +PP T Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCS-----IELKVKEPP---------------TF 4957 Query: 165 LGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ--PSNPLVLELQVHL--- 219 + + V++ + L C V PP ++W + + S+ V +H+ Sbjct: 4958 IRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKC 5017 Query: 220 --GDEGEFTCRAQNSLGSQHVSLNLSLQQ 246 D GE+ C N GS S ++L++ Sbjct: 5018 DPSDTGEYQCIVSNEGGSCSCSTRVALKE 5046 >gi|110349717 titin isoform novex-2 [Homo sapiens] Length = 27118 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/160 (21%), Positives = 78/160 (48%), Gaps = 15/160 (9%) Query: 87 VQEETRDRFHLLGDPQT-KNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTD 145 +QE+ D+++ + T +N ++ D +M +Y FR+ N+K +Y + S+ + Sbjct: 23075 MQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQ--KYSFRVAAVNVKGMSEYSE-SIAEIE 23131 Query: 146 PPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTL--- 202 P + + + + A ++++ G SLRL+ +V PP ++W+ + + L Sbjct: 23132 PVERIEIPDLE------LADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASR 23185 Query: 203 --YPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSL 240 + S L++ +V+ D G++T A+N G + ++ Sbjct: 23186 AIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATV 23225 Score = 40.4 bits (93), Expect = 0.003 Identities = 43/203 (21%), Positives = 74/203 (36%), Gaps = 48/203 (23%) Query: 52 VDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIR 111 V+ + + D V +W++ G +I+++ + V+ F I Sbjct: 3120 VEFEVNEDDVDAHWYKDGIEINFQVQ---ERHKYVVERRIHRMF--------------IS 3162 Query: 112 DARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSL 171 + R SDAG Y F + N L VN +PPQ L + Sbjct: 3163 ETRQSDAGEYTFVAGR-----NRSSVTLYVNAPEPPQ---------------VLQELQPV 3202 Query: 172 SVLEGQSLRLVCAVDSNPPARLSWT---------WRSLTLYPSQPSNPLVLELQVHLGDE 222 +V G+ R + P ++SW ++ L+ Q L++E D Sbjct: 3203 TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPE--DA 3260 Query: 223 GEFTCRAQNSLGSQHVSLNLSLQ 245 +TC A+N G S +LS++ Sbjct: 3261 AVYTCEAKNDYGVATTSASLSVE 3283 Score = 39.3 bits (90), Expect = 0.006 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 7/93 (7%) Query: 161 ASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQ---- 216 A+ L S++V EG+S R C D P ++W + L S + + Sbjct: 26255 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFE 26314 Query: 217 ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQQ 246 V DEG ++ +NS G Q L++Q+ Sbjct: 26315 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26347 Score = 37.4 bits (85), Expect = 0.022 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 7/93 (7%) Query: 160 TASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPS-------QPSNPLV 212 T T + +++V+EG+S+ L C + P ++W + S Q + Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954 Query: 213 LELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245 + + D G FTC A N G+ S L++Q Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987 Score = 36.6 bits (83), Expect = 0.038 Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 7/100 (7%) Query: 158 EGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP-------SNP 210 EGT + S+ + G L V P ++ W + + L PS + Sbjct: 3645 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3704 Query: 211 LVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTG 250 ++ L L DEGE+TC A N G S L + + G Sbjct: 3705 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 3744 Score = 35.4 bits (80), Expect = 0.084 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 171 LSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQP----SNPLVLELQV---HLGDEG 223 L V G + C + S P R W +Y S S+ + L++ + D G Sbjct: 4538 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCG 4597 Query: 224 EFTCRAQNSLGSQHVSLNLSL 244 E+TC+A N GS + L++ Sbjct: 4598 EYTCKASNEYGSVSCTATLTV 4618 Score = 34.3 bits (77), Expect = 0.19 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%) Query: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203 ++P +T+ ++ S L+V G ++ L V P +SW L Sbjct: 12973 SEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLK 13032 Query: 204 PSQ------PSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244 P++ N LEL V+ D G++T A+NS GS+ ++ L + Sbjct: 13033 PAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13080 Score = 32.3 bits (72), Expect = 0.71 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%) Query: 175 EGQSLRLVCAVDSNPPARLSWTWRSLTLYPS------QPSNPLVLEL-QVHLGDEGEFTC 227 EGQ R C V S ++SW + + PS Q + LE+ + + DEG +T Sbjct: 3312 EGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370 Query: 228 RAQNSLGSQHVSLNLSLQ 245 A N++G + NLSL+ Sbjct: 3371 VASNAVGQVSSTANLSLE 3388 Score = 32.3 bits (72), Expect = 0.71 Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 25/145 (17%) Query: 107 TLSIRDARMSDAG--RYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTA 164 TL+I+ A D G + ++G +K Y LS ++D P Sbjct: 26788 TLTIKQASHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDAP---------------AF 26831 Query: 165 LGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL------TLYPSQPSNPLVLELQ-V 217 + S ++ EGQ++ C + P + W +L + S+ N LE++ Sbjct: 26832 ISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNA 26891 Query: 218 HLGDEGEFTCRAQNSLGSQHVSLNL 242 + D G++T +A+N G + +L Sbjct: 26892 SVSDSGKYTIKAKNFRGQCSATASL 26916 Score = 30.4 bits (67), Expect = 2.7 Identities = 38/195 (19%), Positives = 68/195 (34%), Gaps = 51/195 (26%) Query: 59 DPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDA 118 + V G W + G ++ + DR H++ D Q+ L I D DA Sbjct: 2336 ESVEGVWMKDGQEV-----------------QPSDRVHIVIDKQSH--MLLIEDMTKEDA 2376 Query: 119 GRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQS 178 G Y F + + + + SV+V P ++ ++V+EG Sbjct: 2377 GNYSFTIPALGLSTSGRVSVYSVDVITPLKD---------------------VNVIEGTK 2415 Query: 179 LRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLV-------LELQVHLGDEGEFTCRAQN 231 L C V + W + P +V + + H DEG + + Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KL 2471 Query: 232 SLGSQHVSLNLSLQQ 246 +G + NLS+++ Sbjct: 2472 IVGRVETNCNLSVEK 2486 Score = 30.4 bits (67), Expect = 2.7 Identities = 17/86 (19%), Positives = 36/86 (41%), Gaps = 9/86 (10%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSN---------PLVLELQVHL 219 S +S+ EG+ L + CA P ++W+ ++ + ++ + V Sbjct: 27031 SDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQK 27090 Query: 220 GDEGEFTCRAQNSLGSQHVSLNLSLQ 245 D G +T N GS ++N+ ++ Sbjct: 27091 QDGGLYTLSLGNEFGSDSATVNIHIR 27116 Score = 30.0 bits (66), Expect = 3.5 Identities = 19/78 (24%), Positives = 29/78 (37%), Gaps = 21/78 (26%) Query: 108 LSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGN 167 L I++A + DAG Y R+ K +L+ PQN Sbjct: 6214 LVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQN------------------ 6255 Query: 168 SSSLSVLEGQSLRLVCAV 185 L +LEG+ VC++ Sbjct: 6256 ---LEILEGEKAEFVCSI 6270 Score = 29.6 bits (65), Expect = 4.6 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 20/131 (15%) Query: 115 MSDAGRYFFRMEKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTAST---ALGNSSSL 171 +++ +Y FR+ N K V++P + +T Q T + ++ Sbjct: 23394 LNEGEQYLFRIRAQNEK----------GVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI 23443 Query: 172 SVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQ----PSNPLVLELQVH---LGDEGE 224 V G+ + LV + PP SW + L S+ ++ V +L + + D GE Sbjct: 23444 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 23503 Query: 225 FTCRAQNSLGS 235 +T +N G+ Sbjct: 23504 YTLELKNVTGT 23514 Score = 29.3 bits (64), Expect = 6.0 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 169 SSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPL-VLEL------QVHLGD 221 SS SV GQ L++ + P ++WT L L + N L+L + H D Sbjct: 16932 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDD 16991 Query: 222 EGEFTCRAQNSLGSQHVSLNL 242 G++ N +G + S+ + Sbjct: 16992 GGQYGITVANVVGQKTASIEI 17012 Score = 28.9 bits (63), Expect = 7.8 Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 221 DEGEFTCRAQNSLGSQHVSLNLSLQQE 247 D G TCRA N G+ H S L ++ E Sbjct: 1725 DSGIITCRATNKYGTDHTSATLIVKDE 1751 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.131 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,944,444 Number of Sequences: 37866 Number of extensions: 657391 Number of successful extensions: 3114 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 160 Number of HSP's that attempted gapping in prelim test: 1900 Number of HSP's gapped (non-prelim): 1078 length of query: 374 length of database: 18,247,518 effective HSP length: 104 effective length of query: 270 effective length of database: 14,309,454 effective search space: 3863552580 effective search space used: 3863552580 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.