Guide to the Human Genome
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Search of human proteins with 239751294

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751294 PREDICTED: similar to hCG2044133 [Homo sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756808 PREDICTED: similar to hCG2044133 [Homo sapiens]          554   e-158
gi|239751294 PREDICTED: similar to hCG2044133 [Homo sapiens]          554   e-158
gi|239745789 PREDICTED: hypothetical protein LOC728129 [Homo sap...   554   e-158
gi|13562088 leucine-rich repeat-containing 3 precursor [Homo sap...   168   4e-42
gi|16418445 leucine rich repeat containing 3B [Homo sapiens]          163   1e-40
gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom...    74   1e-13
gi|62912470 leucine-rich repeat-containing G protein-coupled rec...    74   2e-13
gi|88702793 slit-like 2 [Homo sapiens]                                 74   2e-13
gi|11321571 slit homolog 3 [Homo sapiens]                              72   4e-13
gi|157694513 leucine-rich repeat-containing G protein-coupled re...    72   5e-13
gi|194440719 chondroadherin-like [Homo sapiens]                        72   7e-13
gi|59823631 G protein-coupled receptor 125 [Homo sapiens]              70   2e-12
gi|225579152 insulin-like growth factor binding protein, acid la...    70   2e-12
gi|4826772 insulin-like growth factor binding protein, acid labi...    70   2e-12
gi|188528675 slit homolog 1 [Homo sapiens]                             69   3e-12
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho...    69   3e-12
gi|229089140 leucine rich repeat containing 24 [Homo sapiens]          67   2e-11
gi|4759146 slit homolog 2 [Homo sapiens]                               67   2e-11
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho...    67   2e-11
gi|13194201 reticulon 4 receptor precursor [Homo sapiens]              66   3e-11
gi|4504379 leucine-rich repeat-containing G protein-coupled rece...    66   4e-11
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo...    65   6e-11
gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens]             65   8e-11
gi|61966761 leucine rich repeat containing 26 [Homo sapiens]           64   1e-10
gi|52353306 leucine rich repeat containing 55 [Homo sapiens]           64   1e-10
gi|15029530 leucine rich repeat containing 4 [Homo sapiens]            62   4e-10
gi|41582239 immunoglobulin superfamily containing leucine-rich r...    62   4e-10
gi|5031809 immunoglobulin superfamily containing leucine-rich re...    62   4e-10
gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo...    62   5e-10
gi|5729718 trophoblast glycoprotein [Homo sapiens]                     62   7e-10

>gi|239756808 PREDICTED: similar to hCG2044133 [Homo sapiens]
          Length = 275

 Score =  554 bits (1428), Expect = e-158
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
           MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
Sbjct: 1   MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60

Query: 61  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
           RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
Sbjct: 61  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120

Query: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
           AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
Sbjct: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180

Query: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
           TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
Sbjct: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240

Query: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
           VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV
Sbjct: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275


>gi|239751294 PREDICTED: similar to hCG2044133 [Homo sapiens]
          Length = 275

 Score =  554 bits (1428), Expect = e-158
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
           MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
Sbjct: 1   MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60

Query: 61  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
           RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
Sbjct: 61  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120

Query: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
           AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
Sbjct: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180

Query: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
           TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
Sbjct: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240

Query: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
           VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV
Sbjct: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275


>gi|239745789 PREDICTED: hypothetical protein LOC728129 [Homo
           sapiens]
          Length = 275

 Score =  554 bits (1428), Expect = e-158
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
           MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
Sbjct: 1   MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60

Query: 61  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
           RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
Sbjct: 61  RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120

Query: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
           AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
Sbjct: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180

Query: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
           TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
Sbjct: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240

Query: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
           VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV
Sbjct: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275


>gi|13562088 leucine-rich repeat-containing 3 precursor [Homo
           sapiens]
          Length = 257

 Score =  168 bits (426), Expect = 4e-42
 Identities = 98/244 (40%), Positives = 136/244 (55%), Gaps = 11/244 (4%)

Query: 20  MAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPN 79
           + ++ T    L LL  +  G   P P      C     AG     CS  GL  VP  IP 
Sbjct: 11  LLLVSTRESCLFLLFCLHLGAACPQP------CRCPDHAGAVAVFCSLRGLQEVPEDIPA 64

Query: 80  DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
           +T  L LDAN+++ +P GAFQHL  L ELDLSHNA+  +  A F GL G LR LDLS N+
Sbjct: 65  NTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLDLSYNR 124

Query: 140 LASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQE 199
           +  +P +A   L  ++ LS NP HC+CALQE L +++L P +   I C +  + + VG+ 
Sbjct: 125 IQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEFVGKP 184

Query: 200 FL-LLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYLVHYVWQNRDETRRSLKRA 258
            +  L     LC        R+TDVA+LVTM GW  +++AY+V+YV  N+++ RR L+  
Sbjct: 185 LVQALDAGASLCSV----PHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEYL 240

Query: 259 PVLP 262
             LP
Sbjct: 241 KSLP 244


>gi|16418445 leucine rich repeat containing 3B [Homo sapiens]
          Length = 259

 Score =  163 bits (413), Expect = 1e-40
 Identities = 88/235 (37%), Positives = 138/235 (58%), Gaps = 8/235 (3%)

Query: 44  SPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLP 103
           S  + P+GC +   +G     CS A L  +P  +P +T  LYLD+NQ+ S+P   F+ L 
Sbjct: 30  SASMCPKGC-LCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLH 88

Query: 104 VLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWH 163
            L  L+LS N +  +   AF+G+  TL+ LDLS N++ SV   AF  L+ +  ++ NPWH
Sbjct: 89  QLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWH 148

Query: 164 CDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDV 223
           CDC LQ+VLR +     T   ++C +    +  G+ FL  A + +LC       +++TD 
Sbjct: 149 CDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNL----PKKTTDY 204

Query: 224 ALLVTMGGWLTLMVAYLVHYVWQNRDETRRSLKRAPVLPVR---SEDSSILSTVV 275
           A+LVTM GW T++++Y+V+YV QN+++ RR L+    LP R   +++   +STVV
Sbjct: 205 AMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV 259


>gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo
           sapiens]
          Length = 592

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/124 (41%), Positives = 64/124 (51%), Gaps = 10/124 (8%)

Query: 30  LPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERT--FRCSQAGLSAVPSGIPNDTRKLYLD 87
           LPLLL+       P+   P  GC    E   +T    C++  L+AVP GIP +TR L L 
Sbjct: 10  LPLLLL-------PAAPPPAGGCPARCECTVQTRAVACTRRRLTAVPDGIPAETRLLELS 62

Query: 88  ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEA 147
            N++  +  G    LP LEELDLS NA+AH+   AF  L   LR L L  NQL  +P   
Sbjct: 63  RNRIRCLNPGDLAALPALEELDLSENAIAHVEPGAFANLP-RLRVLRLRGNQLKLIPPGV 121

Query: 148 FVGL 151
           F  L
Sbjct: 122 FTRL 125



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 3/110 (2%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N +++VP G+F+ L  L EL L+   LA +   AF GL   +R L+LS N L+++
Sbjct: 275 LNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLR-QIRLLNLSNNLLSTL 333

Query: 144 PVEAF--VGLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGA 191
               F  V     + +  NP  CDC L  ++++ + +   G    C + A
Sbjct: 334 EESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPA 383



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L +  N L  V   AF  L  LEEL L    L  LSG +   L  +L  L L    +A
Sbjct: 153 RRLEVGDNDLVFVSRRAFAGLLALEELTLERCNLTALSGESLGHLR-SLGALRLRHLAIA 211

Query: 142 SVPVEAFVGLQIQVNLSANPW 162
           S+  + F  L   ++L  + W
Sbjct: 212 SLEDQNFRRLPGLLHLEIDNW 232


>gi|62912470 leucine-rich repeat-containing G protein-coupled
           receptor 6 isoform 1 [Homo sapiens]
          Length = 967

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 44/105 (41%), Positives = 56/105 (53%), Gaps = 1/105 (0%)

Query: 43  PSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHL 102
           P P   P  C+  ++    +  CS+ GLSAVP  +   T  L L  N L  +  G F HL
Sbjct: 30  PGPTACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHL 89

Query: 103 PVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEA 147
             LEEL LS N L+H+ G AF GL  +L+ L L  NQL  +P EA
Sbjct: 90  RFLEELRLSGNHLSHIPGQAFSGLY-SLKILMLQNNQLGGIPAEA 133



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  NQL  +PA A   LP L+ L L  N ++ +   +F+GL  +LRHL L  N L  +
Sbjct: 119 LMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL-SSLRHLWLDDNALTEI 177

Query: 144 PVEAFVGL 151
           PV A   L
Sbjct: 178 PVRALNNL 185



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 1/79 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R L+LD N L  +P  A  +LP L+ + L+ N ++H+   AFQ L  +L  L L  N++ 
Sbjct: 165 RHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLT-SLVVLHLHNNRIQ 223

Query: 142 SVPVEAFVGLQIQVNLSAN 160
            +   +F GL     L  N
Sbjct: 224 HLGTHSFEGLHNLETLDLN 242



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%)

Query: 86  LDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPV 145
           L  N++  + A  F  L  L+ LDLS NA+  +   AF  L   ++ LDL+ NQL ++P+
Sbjct: 381 LQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVK-LDLTDNQLTTLPL 439

Query: 146 EAFVGL 151
               GL
Sbjct: 440 AGLGGL 445



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           + L LDAN ++ VP  +F+ L  L  L L  NAL  +   A   L   L+ + L+ N+++
Sbjct: 141 QSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP-ALQAMTLALNRIS 199

Query: 142 SVPVEAFVGL 151
            +P  AF  L
Sbjct: 200 HIPDYAFQNL 209



 Score = 36.6 bits (83), Expect = 0.024
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 22/87 (25%)

Query: 86  LDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLE------------------ 127
           L  N+++ +P  AFQ+L  L  L L +N + HL   +F+GL                   
Sbjct: 193 LALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA 252

Query: 128 ----GTLRHLDLSANQLASVPVEAFVG 150
               G L+ L    N + ++P +AF+G
Sbjct: 253 IRTLGRLQELGFHNNNIKAIPEKAFMG 279



 Score = 32.0 bits (71), Expect = 0.60
 Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 21/85 (24%)

Query: 94  VPAGAFQHLPVLEELDLSHNALAHLS---------------------GAAFQGLEGTLRH 132
           +P+G  Q LP L  L+LSHN +  L                      GA       +L+ 
Sbjct: 343 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQA 402

Query: 133 LDLSANQLASVPVEAFVGLQIQVNL 157
           LDLS N + S+  EAF  L   V L
Sbjct: 403 LDLSWNAIRSIHPEAFSTLHSLVKL 427


>gi|88702793 slit-like 2 [Homo sapiens]
          Length = 673

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/124 (39%), Positives = 68/124 (54%), Gaps = 7/124 (5%)

Query: 29  LLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDA 88
           LLPLLL++  G   P  Q  P GC  ++    +T  C+    + VP  +P DT  LY+  
Sbjct: 8   LLPLLLLLALG---PGVQGCPSGCQCSQP---QTVFCTARQGTTVPRDVPPDTVGLYVFE 61

Query: 89  NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
           N +  + AG+F  LP L+ LDLS N +A L    FQ L   L +LDL+AN+L  +  E F
Sbjct: 62  NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPL-ANLSNLDLTANRLHEITNETF 120

Query: 149 VGLQ 152
            GL+
Sbjct: 121 RGLR 124



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 83  KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
           +LYL  N++  +  GAF  L  L EL L  N L  L           L  LDLS N L +
Sbjct: 128 RLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLP----RLLLLDLSHNSLLA 183

Query: 143 V 143
           +
Sbjct: 184 L 184


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 53/159 (33%), Positives = 74/159 (46%), Gaps = 33/159 (20%)

Query: 39  GGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPA-- 96
           G    S Q+ PR C       E   RCS  GL A+P G+P D  +LYL+ N L +VP   
Sbjct: 713 GNEESSCQLSPR-CPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPREL 771

Query: 97  GAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQI--- 153
            A +HL ++   DLS+N+++ L+   F  +   L  L LS N+L  +PV AF GL+    
Sbjct: 772 SALRHLTLI---DLSNNSISMLTNYTFSNMSH-LSTLILSYNRLRCIPVHAFNGLRSLRV 827

Query: 154 -----------------------QVNLSANPWHCDCALQ 169
                                   + L  NP HCDC+L+
Sbjct: 828 LTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLR 866



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 50/169 (29%), Positives = 66/169 (39%), Gaps = 27/169 (15%)

Query: 32  LLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDT---------- 81
           L L +     +  P  P   C         +  C   GL AVP GIP +           
Sbjct: 16  LALALALASVLSGP--PAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNI 73

Query: 82  --------------RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLE 127
                         R L+L+ NQ++ +  GAFQ L  LE L L+ N L  L    FQ   
Sbjct: 74  TRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTP 133

Query: 128 GTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
             L  LDLS NQ+  +P +AF G+    NL  +  H  C      R +R
Sbjct: 134 -KLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 181



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 3/102 (2%)

Query: 65  CSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
           C   GL  +P+ +P    ++ L+ N + ++PAGAF     L+ +D+S N ++ ++  AFQ
Sbjct: 293 CRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQ 352

Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGL-QIQ-VNLSANPWHC 164
           GL+ +L  L L  N++  +    F GL  +Q + L+AN  +C
Sbjct: 353 GLK-SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 393



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 40/133 (30%), Positives = 61/133 (45%), Gaps = 31/133 (23%)

Query: 77  IPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLS 136
           +PN  RK+ L  N++  V  GAF     ++EL L+ N L  + G  F+GL G L+ L L 
Sbjct: 556 LPN-LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSG-LKTLMLR 613

Query: 137 ANQLASVPVEAFVGLQ--------------------------IQVNLSANPWHCDCALQ- 169
           +N +  V  + F GL                             +NL +NP++C+C L  
Sbjct: 614 SNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAW 673

Query: 170 --EVLRQVRLVPG 180
             + LR+ R+V G
Sbjct: 674 LGKWLRKRRIVSG 686



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 2/88 (2%)

Query: 65  CSQAGLSAVPSGIPNDTRKLYLDANQLASVPA-GAFQHLPVLEELDLSHNALAHLSGAAF 123
           CS   L  +PS +P     L L+ N+++ + A G F+ LP L +++LS+N +  +   AF
Sbjct: 518 CSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAF 577

Query: 124 QGLEGTLRHLDLSANQLASVPVEAFVGL 151
            G   +++ L L+ NQL +V    F GL
Sbjct: 578 DG-AASVQELMLTGNQLETVHGRVFRGL 604



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N++  +  G F  L  L+ L L+ N +  L    FQ L+  L  L L  N+L ++
Sbjct: 360 LVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQ-NLNLLSLYDNKLQTI 418

Query: 144 PVEAFVGLQ-IQ-VNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGAR 192
               F  LQ IQ ++L+ NP+ CDC L+ +   ++  P   +G  C S  R
Sbjct: 419 SKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRR 469


>gi|157694513 leucine-rich repeat-containing G protein-coupled
           receptor 4 [Homo sapiens]
          Length = 951

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 46/125 (36%), Positives = 63/125 (50%), Gaps = 1/125 (0%)

Query: 39  GGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGA 98
           G   PS   PP         G+R   CS  GL+AVP G+   T+ L +  N +  +P  A
Sbjct: 17  GSAGPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDA 76

Query: 99  FQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLS 158
           F++ P LEEL L+ N L+ +   A  GL+  L+ L L  NQL +VP EA  GL    +L 
Sbjct: 77  FKNFPFLEELQLAGNDLSFIHPKALSGLK-ELKVLTLQNNQLKTVPSEAIRGLSALQSLR 135

Query: 159 ANPWH 163
            +  H
Sbjct: 136 LDANH 140



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 83  KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
           ++ L  NQ+  +  G FQ L  L  LDLS N +  +   AF  L G + +LD+S N+L S
Sbjct: 369 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATL-GPITNLDVSFNELTS 427

Query: 143 VPVEAFVGLQIQVNLSAN 160
            P E   GL  Q+ L  N
Sbjct: 428 FPTEGLNGLN-QLKLVGN 444



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 17/108 (15%)

Query: 69  GLSAVPS---------GIPNDT-------RKLYLDANQLASVPAGAFQHLPVLEELDLSH 112
           GLSA+ S          +P D+       R L+LD N L  VP     +LP L+ L L+ 
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186

Query: 113 NALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSAN 160
           N ++ +   AF  L  +L  L L  N++ S+    F GL     L  N
Sbjct: 187 NKISSIPDFAFTNL-SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLN 233



 Score = 31.6 bits (70), Expect = 0.79
 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L   +++S+P    Q   +L  LDLS+N +  L   +F G    L  + L  NQ+  +
Sbjct: 324 LTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCH-ALEEISLQRNQIYQI 380

Query: 144 PVEAFVGL 151
               F GL
Sbjct: 381 KEGTFQGL 388



 Score = 31.2 bits (69), Expect = 1.0
 Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 5/57 (8%)

Query: 70  LSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGL 126
           + A+PS      ++L   +N ++ +P GAF   P+L  + L  N L+ +  +AF  L
Sbjct: 244 IKALPS-----LKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNL 295


>gi|194440719 chondroadherin-like [Homo sapiens]
          Length = 762

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 57/180 (31%), Positives = 82/180 (45%), Gaps = 31/180 (17%)

Query: 64  RCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAF 123
           R ++  L A+  G   +  KL+LD NQL  VP GA + LP L EL LS N L  L   AF
Sbjct: 556 RITEVSLGAL--GPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAF 613

Query: 124 QGLEGTLRHLDLSANQLASVPVEAFVGL------------------------QIQ-VNLS 158
           Q +  +L+HL L+++ L  +   AF GL                        Q++ ++LS
Sbjct: 614 QPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLS 673

Query: 159 ANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGAR 218
           +NP+HCDC   ++L   R + G    +       P+  GQ     A   E C  GW   +
Sbjct: 674 SNPFHCDC---QLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDC-PGWAARK 729



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 3/102 (2%)

Query: 49  PRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEEL 108
           PR C    E+  R   C   GL AVP G P+DT+ L L  N   SVP  AF  L  L  L
Sbjct: 397 PRACVCVPES--RHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSL 454

Query: 109 DLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVG 150
            L H  +A L   A  GL G L +L LS NQLA +   A  G
Sbjct: 455 HLQHCGIAELEAGALAGL-GRLIYLYLSDNQLAGLSAAALEG 495



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 4/124 (3%)

Query: 29  LLPLL-LVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLD 87
           +LPLL L++       + Q  P+ C    +   R   C    L+ VP  IP  T++L L 
Sbjct: 13  VLPLLVLLLLAPARQAAAQRCPQACIC--DNSRRHVACRYQNLTEVPDAIPELTQRLDLQ 70

Query: 88  ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEA 147
            N L  +PA AFQ +P L  LDL H  +  ++  AF+GL G L  L+L++N L  +P EA
Sbjct: 71  GNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGL-GRLLLLNLASNHLRELPQEA 129

Query: 148 FVGL 151
             GL
Sbjct: 130 LDGL 133



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 37/95 (38%), Positives = 47/95 (49%), Gaps = 1/95 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L L+ N L  +  G F  L  L  L+L+HNAL +L   AFQGL   +R L LS N L+
Sbjct: 137 RRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLL-RVRWLRLSHNALS 195

Query: 142 SVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
            +  EA  GL     LS +          VL Q R
Sbjct: 196 VLAPEALAGLPALRRLSLHHNELQALPGPVLSQAR 230



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 46/137 (33%), Positives = 57/137 (41%), Gaps = 29/137 (21%)

Query: 68  AGLSAVP-SGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNAL----------- 115
           AGLSA    G P     LYL+ N+   VP  A + LP L  L L  NA+           
Sbjct: 486 AGLSAAALEGAPR-LGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRT 544

Query: 116 -----AHLSGAAFQ----GLEGTLRHLD---LSANQLASVPVEAFVGLQ--IQVNLSANP 161
                 +LSG        G  G  R L+   L  NQL  VP  A  GL   +++ LS NP
Sbjct: 545 RALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNP 604

Query: 162 WHC--DCALQEVLRQVR 176
                D A Q V R ++
Sbjct: 605 LRALRDGAFQPVGRSLQ 621



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 39/139 (28%), Positives = 54/139 (38%), Gaps = 28/139 (20%)

Query: 61  RTFRCSQAGLSAVP----SGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALA 116
           R  R S   LS +     +G+P   R+L L  N+L ++P         L  L+L HN L 
Sbjct: 185 RWLRLSHNALSVLAPEALAGLPA-LRRLSLHHNELQALPGPVLSQARGLARLELGHNPLT 243

Query: 117 H----------------LSGAAFQGLEGT-------LRHLDLSANQLASVPVEAFVGLQI 153
           +                L G A Q L          L  LDL  NQL ++P     G   
Sbjct: 244 YAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLR 303

Query: 154 QVNLSANPWHCDCALQEVL 172
           ++ L  NP  C C  + +L
Sbjct: 304 RLRLQGNPLWCGCQARPLL 322


>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
          Length = 1321

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 54/158 (34%), Positives = 82/158 (51%), Gaps = 15/158 (9%)

Query: 15  GLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVP--------PRGCYVAKEAGERTFRCS 66
           G  Q   +LP +  LL LL ++G GG   +  +P        PRG   A  A E    CS
Sbjct: 9   GRAQPPLLLPLS--LLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCS 66

Query: 67  QAGLSAV--PSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
              L+ V  P  +PN T  L L  N+++ +  G+F  L +LE LDL +N ++ +   AF 
Sbjct: 67  SLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFW 126

Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSAN 160
           GL  +L+ LDL+ N++  +  + F GL   +++NLS N
Sbjct: 127 GL-SSLKRLDLTNNRIGCLNADIFRGLTNLVRLNLSGN 163


>gi|225579152 insulin-like growth factor binding protein, acid
           labile subunit isoform 1 precursor [Homo sapiens]
          Length = 643

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 45/113 (39%), Positives = 57/113 (50%), Gaps = 2/113 (1%)

Query: 37  GTGGTVPSPQVPPRG-CYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVP 95
           GT G    P  P    C    +A E +  CS   L+ +P G+P  T+ L+LD N L+SVP
Sbjct: 69  GTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 128

Query: 96  AGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
             AFQ+L  L  L+L    L  L   A  GLE  L HL L  NQL S+ +  F
Sbjct: 129 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLE-NLCHLHLERNQLRSLALGTF 180



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 35/70 (50%), Positives = 41/70 (58%), Gaps = 1/70 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           +KLYLD N +A+V  GAF  L  L  LDLSHN +A L    F GL G LR L LS N +A
Sbjct: 283 QKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLG-LRVLRLSHNAIA 341

Query: 142 SVPVEAFVGL 151
           S+    F  L
Sbjct: 342 SLRPRTFKDL 351



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/81 (43%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R L L  N +AS+    F+ L  LEEL L HN +  L+  +F+GL G L  L L  NQL 
Sbjct: 331 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGL-GQLEVLTLDHNQLQ 389

Query: 142 SVPVEAFVGLQ--IQVNLSAN 160
            V   AF+GL     +NLS N
Sbjct: 390 EVKAGAFLGLTNVAVMNLSGN 410



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 31/71 (43%), Positives = 40/71 (56%), Gaps = 1/71 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L+L  N L  +   +   L  L ELDL+ N L HL    FQGL G L +L LS N+LA
Sbjct: 451 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGL-GKLEYLLLSRNRLA 509

Query: 142 SVPVEAFVGLQ 152
            +P +A   LQ
Sbjct: 510 ELPADALGPLQ 520



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 32/68 (47%), Positives = 38/68 (55%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N LA +P  AF+ L  L EL L+ N LA+L  A F GL   LR LDLS N L ++
Sbjct: 213 LNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGL-AELRELDLSRNALRAI 271

Query: 144 PVEAFVGL 151
               FV L
Sbjct: 272 KANVFVQL 279



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)

Query: 80  DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
           + R+L L  N L ++ A  F  LP L++L L  N +A ++  AF GL+  LR LDLS N+
Sbjct: 257 ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLK-ALRWLDLSHNR 315

Query: 140 LASVPVEAFVGL 151
           +A +  + F GL
Sbjct: 316 VAGLLEDTFPGL 327



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 42/132 (31%), Positives = 58/132 (43%), Gaps = 7/132 (5%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N+LA +PA A   L     LD+SHN L  L  +    L G LR+L L  N L + 
Sbjct: 501 LLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPL-GRLRYLSLRNNSLRTF 559

Query: 144 PVEAFVGLQIQVNLSANPWHCDCALQEV----LRQVRLVPGTGTGIVCGSGARPDLVGQE 199
             +   GL+ ++ L  NPW C C L+ +    L+    VP     I  G   +P      
Sbjct: 560 TPQP-PGLE-RLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYN 617

Query: 200 FLLLAGEEELCG 211
            +  A   E+ G
Sbjct: 618 NITCASPPEVVG 629



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L L  N+LA +    F  L  L ELDLS NAL  +    F  L   L+ L L  N +A
Sbjct: 235 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP-RLQKLYLDRNLIA 293

Query: 142 SVPVEAFVGLQ 152
           +V   AF+GL+
Sbjct: 294 AVAPGAFLGLK 304



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L LD NQL  V AGAF  L  +  ++LS N L +L    F+GL G L  L L  + L  +
Sbjct: 381 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGL-GKLHSLHLEGSCLGRI 439

Query: 144 PVEAFVGL 151
               F GL
Sbjct: 440 RPHTFTGL 447


>gi|4826772 insulin-like growth factor binding protein, acid labile
           subunit isoform 2 precursor [Homo sapiens]
          Length = 605

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 45/113 (39%), Positives = 57/113 (50%), Gaps = 2/113 (1%)

Query: 37  GTGGTVPSPQVPPRG-CYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVP 95
           GT G    P  P    C    +A E +  CS   L+ +P G+P  T+ L+LD N L+SVP
Sbjct: 31  GTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 90

Query: 96  AGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
             AFQ+L  L  L+L    L  L   A  GLE  L HL L  NQL S+ +  F
Sbjct: 91  PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLE-NLCHLHLERNQLRSLALGTF 142



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 35/70 (50%), Positives = 41/70 (58%), Gaps = 1/70 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           +KLYLD N +A+V  GAF  L  L  LDLSHN +A L    F GL G LR L LS N +A
Sbjct: 245 QKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLG-LRVLRLSHNAIA 303

Query: 142 SVPVEAFVGL 151
           S+    F  L
Sbjct: 304 SLRPRTFKDL 313



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/81 (43%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R L L  N +AS+    F+ L  LEEL L HN +  L+  +F+GL G L  L L  NQL 
Sbjct: 293 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGL-GQLEVLTLDHNQLQ 351

Query: 142 SVPVEAFVGLQ--IQVNLSAN 160
            V   AF+GL     +NLS N
Sbjct: 352 EVKAGAFLGLTNVAVMNLSGN 372



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 31/71 (43%), Positives = 40/71 (56%), Gaps = 1/71 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L+L  N L  +   +   L  L ELDL+ N L HL    FQGL G L +L LS N+LA
Sbjct: 413 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGL-GKLEYLLLSRNRLA 471

Query: 142 SVPVEAFVGLQ 152
            +P +A   LQ
Sbjct: 472 ELPADALGPLQ 482



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 32/68 (47%), Positives = 38/68 (55%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N LA +P  AF+ L  L EL L+ N LA+L  A F GL   LR LDLS N L ++
Sbjct: 175 LNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGL-AELRELDLSRNALRAI 233

Query: 144 PVEAFVGL 151
               FV L
Sbjct: 234 KANVFVQL 241



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)

Query: 80  DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
           + R+L L  N L ++ A  F  LP L++L L  N +A ++  AF GL+  LR LDLS N+
Sbjct: 219 ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLK-ALRWLDLSHNR 277

Query: 140 LASVPVEAFVGL 151
           +A +  + F GL
Sbjct: 278 VAGLLEDTFPGL 289



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 42/132 (31%), Positives = 58/132 (43%), Gaps = 7/132 (5%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N+LA +PA A   L     LD+SHN L  L  +    L G LR+L L  N L + 
Sbjct: 463 LLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPL-GRLRYLSLRNNSLRTF 521

Query: 144 PVEAFVGLQIQVNLSANPWHCDCALQEV----LRQVRLVPGTGTGIVCGSGARPDLVGQE 199
             +   GL+ ++ L  NPW C C L+ +    L+    VP     I  G   +P      
Sbjct: 522 TPQP-PGLE-RLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYN 579

Query: 200 FLLLAGEEELCG 211
            +  A   E+ G
Sbjct: 580 NITCASPPEVVG 591



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L L  N+LA +    F  L  L ELDLS NAL  +    F  L   L+ L L  N +A
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP-RLQKLYLDRNLIA 255

Query: 142 SVPVEAFVGLQ 152
           +V   AF+GL+
Sbjct: 256 AVAPGAFLGLK 266



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L LD NQL  V AGAF  L  +  ++LS N L +L    F+GL G L  L L  + L  +
Sbjct: 343 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGL-GKLHSLHLEGSCLGRI 401

Query: 144 PVEAFVGL 151
               F GL
Sbjct: 402 RPHTFTGL 409


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 50/157 (31%), Positives = 70/157 (44%), Gaps = 33/157 (21%)

Query: 39  GGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGA 98
           GG +P PQ P     +     +   RCS   L A+P GIP +  +LYLD NQ   VP G 
Sbjct: 726 GGCLPRPQCPQECACL-----DTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVP-GQ 779

Query: 99  FQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQI----- 153
                 L+ +DLS+N ++ LS ++F  +   L  L LS N L  +P  AF GL+      
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMS-QLTTLILSYNALQCIPPLAFQGLRSLRLLS 838

Query: 154 ---------------------QVNLSANPWHCDCALQ 169
                                 + + ANP +CDC L+
Sbjct: 839 LHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLR 875



 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 54/205 (26%), Positives = 84/205 (40%), Gaps = 49/205 (23%)

Query: 37  GTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPA 96
           G  G VP+  +    C            C   GL+A+P+ +P    ++ L+ N + S+P 
Sbjct: 267 GEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPP 326

Query: 97  GAFQHLPVLEELDLSHNALAHLSGAAFQGLEG-----------------------TLRHL 133
           GAF     L  +DLS+N +A ++  AFQGL                         TL+ L
Sbjct: 327 GAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLL 386

Query: 134 DLSANQLASVPVEAFVGLQ-------------------------IQ-VNLSANPWHCDCA 167
            L+AN++  +  +AF  LQ                         IQ ++L+ NP+ CDC 
Sbjct: 387 LLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446

Query: 168 LQEVLRQVRLVPGTGTGIVCGSGAR 192
           L+ +   +R  P   +G  C S  R
Sbjct: 447 LKWLADFLRTNPIETSGARCASPRR 471



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 25/139 (17%)

Query: 62  TFRCSQAGLSAVPSGIPNDTRKLYLDA------------------------NQLASVPAG 97
           T  C   GL A+P  IP +T +L L+                         NQ+ +V  G
Sbjct: 44  TVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERG 103

Query: 98  AFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNL 157
           AF  +  LE L L+ N L  L    FQ  +  L  LDLS N + ++P +AF G     NL
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQ-ALSRLDLSENAIQAIPRKAFRGATDLKNL 162

Query: 158 SANPWHCDCALQEVLRQVR 176
             +     C  +   R +R
Sbjct: 163 QLDKNQISCIEEGAFRALR 181



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 55/170 (32%)

Query: 65  CSQAGLSAVPSGIPNDT-------------------------RKLYLDANQLASVPAGAF 99
           CS   L+ +P  IP  T                         +K+ L  N+++ +  GAF
Sbjct: 526 CSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAF 585

Query: 100 QHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQ------- 152
           +    + EL L+ N L  +    F+GL+G LR L L  N+++ +  ++F GL+       
Sbjct: 586 EGAASVSELHLTANQLESIRSGMFRGLDG-LRTLMLRNNRISCIHNDSFTGLRNVRLLSL 644

Query: 153 -------------------IQVNLSANPWHCDCALQEV---LRQVRLVPG 180
                                +NL ANP++C+C L  +   LR+ ++V G
Sbjct: 645 YDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTG 694



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 41/139 (29%), Positives = 62/139 (44%), Gaps = 6/139 (4%)

Query: 83  KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
           +L L  N + ++P  AF+    L+ L L  N ++ +   AF+ L G L  L L+ N + +
Sbjct: 137 RLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG-LEVLTLNNNNITT 195

Query: 143 VPVEAFVGLQ--IQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEF 200
           +PV +F  +       L +N   CDC L  + + +R  P  G    C   A   L G   
Sbjct: 196 IPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPA--SLRGLNV 253

Query: 201 LLLAGEEELCGSGWGGARR 219
             +   E  C SG G A R
Sbjct: 254 AEVQKSEFSC-SGQGEAGR 271


>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
           sapiens]
          Length = 345

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 44/114 (38%), Positives = 69/114 (60%), Gaps = 5/114 (4%)

Query: 49  PRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEEL 108
           P  CY   ++      CSQ GL+ +PS +P  TR L+L  NQ+  +PA AF+ +P L  L
Sbjct: 22  PDKCYC--QSSTNFVDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLMTL 79

Query: 109 DLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSAN 160
           +LS+N+L++L+  AF GL+  L+ L+L+ N L S+    F  L    +++LS+N
Sbjct: 80  NLSNNSLSNLAPGAFHGLQ-HLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSN 132


>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
          Length = 513

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 42/90 (46%), Positives = 52/90 (57%), Gaps = 5/90 (5%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R LYL  NQLA +    F HLP L+EL L  N++  L   A  GL  +L  LDLS NQL 
Sbjct: 125 RVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGL-SSLALLDLSRNQLG 183

Query: 142 SVPVEA---FVGLQIQVNLSANPWHCDCAL 168
           ++  EA      LQ+ + L+ NPW CDCAL
Sbjct: 184 TISREALQPLASLQV-LRLTENPWRCDCAL 212



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 45/125 (36%), Positives = 60/125 (48%), Gaps = 13/125 (10%)

Query: 29  LLPLLLVIGTGGTVPSPQVPPR--GCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYL 86
           LLPLLL++          +P R  GC  A      T  C    L  VP GIP  T+ L+L
Sbjct: 8   LLPLLLLL----------LPLRAAGCPAACRCYSATVECGALRLRVVPLGIPPGTQTLFL 57

Query: 87  DANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVE 146
             N +A +  GA   L  L  L L +N+L  L   AF+  +  L  L L++N+L  +   
Sbjct: 58  QDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRA-QPRLLELALTSNRLRGLRSG 116

Query: 147 AFVGL 151
           AFVGL
Sbjct: 117 AFVGL 121


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 46/131 (35%), Positives = 63/131 (48%), Gaps = 26/131 (19%)

Query: 64  RCSQAGLSAVPSGIPNDTRKLYLDANQLASVP--AGAFQHLPVLE--------------- 106
           RCS  GL  +P GIP D  +LYLD NQ   VP     ++HL +++               
Sbjct: 739 RCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFS 798

Query: 107 ------ELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLS-- 158
                  L LS+N L  +    F GL+ +LR L L  N ++ VP  AF  L    +L+  
Sbjct: 799 NMTQLLTLILSYNRLRCIPPRTFDGLK-SLRLLSLHGNDISVVPEGAFNDLSALSHLAIG 857

Query: 159 ANPWHCDCALQ 169
           ANP +CDC +Q
Sbjct: 858 ANPLYCDCNMQ 868



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)

Query: 52  CYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLS 111
           C  A         C   GL+ +P+ +P    ++ L+ N +  +P GAF     L  +DLS
Sbjct: 273 CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLS 332

Query: 112 HNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGL-QIQ-VNLSANPWHC 164
           +N ++ L+  AFQGL  +L  L L  N++  +P   F GL  +Q + L+AN  +C
Sbjct: 333 NNQISELAPDAFQGLR-SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 53/172 (30%)

Query: 62  TFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPA-GAFQHLPVLEELDLSHNALAHLSG 120
           T  CS   L+ +P  IP  T +L L+ N+   + A G F+ LP L +++ S+N +  +  
Sbjct: 516 TVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEE 575

Query: 121 AAFQGLEG-----------------------TLRHLDLSANQLASVPVEAFVGLQI---- 153
            AF+G  G                       +L+ L L +N++  V  ++F+GL      
Sbjct: 576 GAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLL 635

Query: 154 ----------------------QVNLSANPWHCDCALQ---EVLRQVRLVPG 180
                                  +NL ANP++C+C L    E LR+ R+V G
Sbjct: 636 SLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTG 687



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 43/155 (27%), Positives = 61/155 (39%), Gaps = 25/155 (16%)

Query: 46  QVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDA----------------- 88
           +V P+ C         T  C    L +VP  IP +T +L L+                  
Sbjct: 22  KVAPQACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHL 81

Query: 89  -------NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
                  N+++++  GAFQ L  LE L L+ N L       F G    L  LDLS NQ+ 
Sbjct: 82  RVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLG-TAKLYRLDLSENQIQ 140

Query: 142 SVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
           ++P +AF G     NL  +     C      R +R
Sbjct: 141 AIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 1/61 (1%)

Query: 80  DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
           D + L LD NQ++ +  GAF+ L  LE L L++N +  LS A+F  +   LR   L +N 
Sbjct: 152 DIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMP-KLRTFRLHSNN 210

Query: 140 L 140
           L
Sbjct: 211 L 211


>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
           sapiens]
          Length = 370

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 51/155 (32%), Positives = 65/155 (41%), Gaps = 49/155 (31%)

Query: 65  CSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
           CS  GL+ VP  +P  TR L L  N+L+++P+ AF +L  L+ LDLS+N L  L  + F 
Sbjct: 54  CSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFG 113

Query: 125 GLEG-----------------------TLRHLDLSANQLASVPVEAFVGLQIQVNLSA-- 159
            L                          LRHLDLS N LA +P   F GL    +LS   
Sbjct: 114 DLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRS 173

Query: 160 ------------------------NPWHCDCALQE 170
                                   NPW CDC L+E
Sbjct: 174 NRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLRE 208


>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
          Length = 473

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 46/140 (32%), Positives = 74/140 (52%), Gaps = 12/140 (8%)

Query: 77  IPNDTRK-------LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGT 129
           +P+DT +       L+L  N+++SVP  AF+ L  L+ L L  N +AH+   AF+ L G 
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDL-GR 227

Query: 130 LRHLDLSANQLASVPVEAFVGLQI--QVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVC 187
           L  L L AN L+++P EA   L+    + L+ NPW CDC  + +   ++   G+ + + C
Sbjct: 228 LMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPC 287

Query: 188 GSGARPDLVGQEFLLLAGEE 207
               R  L G++   LA  +
Sbjct: 288 SLPQR--LAGRDLKRLAAND 305



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 50/126 (39%), Positives = 64/126 (50%), Gaps = 8/126 (6%)

Query: 48  PPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEE 107
           P  G  V     + T  C Q GL AVP GIP  +++++L  N+++ VPA +F+    L  
Sbjct: 26  PCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTI 85

Query: 108 LDLSHNALAHLSGAAFQGLEGTLRHLDLSAN-QLASVPVEAFVGLQIQVNLSANPWHCD- 165
           L L  N LA +  AAF GL   L  LDLS N QL SV    F GL        +  H D 
Sbjct: 86  LWLHSNVLARIDAAAFTGL-ALLEQLDLSDNAQLRSVDPATFHGLG-----RLHTLHLDR 139

Query: 166 CALQEV 171
           C LQE+
Sbjct: 140 CGLQEL 145



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/68 (42%), Positives = 37/68 (54%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L+LD   L  +  G F+ L  L+ L L  NAL  L    F+ L G L HL L  N+++SV
Sbjct: 135 LHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDL-GNLTHLFLHGNRISSV 193

Query: 144 PVEAFVGL 151
           P  AF GL
Sbjct: 194 PERAFRGL 201


>gi|4504379 leucine-rich repeat-containing G protein-coupled
           receptor 5 [Homo sapiens]
          Length = 907

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 51/139 (36%), Positives = 68/139 (48%), Gaps = 6/139 (4%)

Query: 30  LPLLLVIGTGGTVPSPQVPPRGCYV---AKEAGERTFR--CSQAGLSAVPSGIPNDTRKL 84
           LP+LL + TGG+ P   V  RGC      +  G    R  CS  GLS +PS +   T  L
Sbjct: 12  LPVLLQLATGGSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYL 71

Query: 85  YLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVP 144
            L  N ++ +       L  LEEL L+ NAL ++   AF GL  +L+ L L  NQL  VP
Sbjct: 72  DLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY-SLKVLMLQNNQLRHVP 130

Query: 145 VEAFVGLQIQVNLSANPWH 163
            EA   L+   +L  +  H
Sbjct: 131 TEALQNLRSLQSLRLDANH 149



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 6/104 (5%)

Query: 61  RTFRCSQAGLSAVP----SGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALA 116
           ++ R     +S VP    SG+ +  R L+LD N L  +P  AF+ L  L+ + L+ N + 
Sbjct: 141 QSLRLDANHISYVPPSCFSGL-HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIH 199

Query: 117 HLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSAN 160
           H+   AF  L  +L  L L  N++ S+  + F GL     L  N
Sbjct: 200 HIPDYAFGNL-SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           +K+ L  N++  +    FQ L  L  L+L+ N +A +   AF  L   ++ LDLS+N L+
Sbjct: 377 QKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIK-LDLSSNLLS 435

Query: 142 SVPVEAFVGL 151
           S P+    GL
Sbjct: 436 SFPITGLHGL 445



 Score = 35.8 bits (81), Expect = 0.042
 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 8/98 (8%)

Query: 68  AGLSAVPSGIPNDTRKLY---LDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
           A +S++P  + N    L    L  N L  +P+  F     L+++DL HN +  +    FQ
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQ 395

Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSAN 160
            L  +LR L+L+ N++A +   AF  L   I+++LS+N
Sbjct: 396 QLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 432



 Score = 35.4 bits (80), Expect = 0.054
 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L+L  N++ S+    F  L  LE LDL++N L      A + L   L+ L   +N + S+
Sbjct: 215 LHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSN-LKELGFHSNNIRSI 272

Query: 144 PVEAFVG 150
           P +AFVG
Sbjct: 273 PEKAFVG 279



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L   Q++S+P      LP L+ LDLS+N L  L   +   +   L+ +DL  N++  +
Sbjct: 333 LTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFS---VCQKLQKIDLRHNEIYEI 389

Query: 144 PVEAF 148
            V+ F
Sbjct: 390 KVDTF 394



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 6/58 (10%)

Query: 89  NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGT--LRHLDLSANQLASVP 144
           N +  V   AFQHLP L  L L  N  + ++   F  L GT  L  L L+  Q++S+P
Sbjct: 291 NPIQFVGRSAFQHLPELRTLTL--NGASQIT--EFPDLTGTANLESLTLTGAQISSLP 344


>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
           sapiens]
          Length = 606

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 39/94 (41%), Positives = 53/94 (56%), Gaps = 1/94 (1%)

Query: 58  AGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAH 117
           A  ++  C +  L A+P GIP +T+ L L  N+L SV    F   P+LEE+DLS N +A+
Sbjct: 36  AQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIAN 95

Query: 118 LSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGL 151
           +   AF  L   LR L L  N+L  VP+  F GL
Sbjct: 96  VEPGAFNNL-FNLRSLRLKGNRLKLVPLGVFTGL 128



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 1/95 (1%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R L L  N+L  VP G F  L  L +LD+S N +  L    FQ L   L+ L++  N L 
Sbjct: 108 RSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLH-NLKSLEVGDNDLV 166

Query: 142 SVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
            +   AF GL     L+    +      E L  +R
Sbjct: 167 YISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLR 201



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N ++++ AG F  L  L+EL +    L  +   +FQGL   LR L++S N L ++
Sbjct: 278 LNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR-FLRVLNVSQNLLETL 336

Query: 144 PVEAFV---GLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLV 196
               F     L++ ++++ NP  CDC L  +L++   +   G   +C   A PD +
Sbjct: 337 EENVFSSPRALEV-LSINNNPLACDCRLLWILQRQPTLQFGGQQPMC---AGPDTI 388



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 83  KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
           +L L+   L +VP  A  HL  L  L L H  + ++   AF+ L   L+HL++    L  
Sbjct: 181 QLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRL-FHLKHLEIDYWPLLD 239

Query: 143 -VPVEAFVGLQI------QVNLSANPW 162
            +P  +  GL +        NLS  P+
Sbjct: 240 MMPANSLYGLNLTSLSVTNTNLSTVPF 266


>gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens]
          Length = 620

 Score = 64.7 bits (156), Expect = 8e-11
 Identities = 44/120 (36%), Positives = 65/120 (54%), Gaps = 4/120 (3%)

Query: 32  LLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQL 91
           LLLV+G+  +  +   PPR C  +  A +R   C +    AVP GIP +TR L L  N++
Sbjct: 27  LLLVLGSVLSGSATGCPPR-CECS--AQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRI 83

Query: 92  ASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGL 151
            ++    F   P LEEL+L+ N ++ +   AF  L   LR L L +N+L  +P+  F GL
Sbjct: 84  KTLNQDEFASFPHLEELELNENIVSAVEPGAFNNL-FNLRTLGLRSNRLKLIPLGVFTGL 142



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R L L  N ++++       L  L+E+ L    LA +   AF+GL   LR L++S NQL 
Sbjct: 290 RFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGL-NYLRVLNVSGNQLT 348

Query: 142 SVPVEAF--VGLQIQVNLSANPWHCDCALQEVLRQ 174
           ++    F  VG    + L +NP  CDC L  V R+
Sbjct: 349 TLEESVFHSVGNLETLILDSNPLACDCRLLWVFRR 383



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 4/85 (4%)

Query: 70  LSAVPSGIPNDT---RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGL 126
           +SAV  G  N+    R L L +N+L  +P G F  L  L +LD+S N +  L    FQ L
Sbjct: 107 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 166

Query: 127 EGTLRHLDLSANQLASVPVEAFVGL 151
              L+ L++  N L  +   AF GL
Sbjct: 167 Y-NLKSLEVGDNDLVYISHRAFSGL 190


>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
          Length = 334

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 1/94 (1%)

Query: 65  CSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
           CS   L AVP G+    R L LD N++ ++P GAF     L+ LDL  N L  +   AF 
Sbjct: 57  CSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFW 116

Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLS 158
           GL G L+ LDLSANQL ++    F  L+   NLS
Sbjct: 117 GL-GALQLLDLSANQLEALAPGTFAPLRALRNLS 149



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L ANQL ++  G F  L  L  L L+ N LA L  AA   L   LR L L  N+LA++
Sbjct: 124 LDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALP-LLRSLSLQDNELAAL 182

Query: 144 PVEAFVGLQI--QVNLSANPWHCDCALQEVLRQVRLVP 179
                  L     ++L  NPW C CAL+ +   +R  P
Sbjct: 183 APGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHP 220


>gi|52353306 leucine rich repeat containing 55 [Homo sapiens]
          Length = 341

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 52/155 (33%), Positives = 71/155 (45%), Gaps = 10/155 (6%)

Query: 14  PGLCQFMAMLPTAGHLLPLLLVIG---TGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGL 70
           P +    A LP  G   P +L+I      G + S       C V      +   CS   L
Sbjct: 42  PKMGDTWAQLPWPGPPHPAMLLISLLLAAGLMHSDA--GTSCPVLCTCRNQVVDCSSQRL 99

Query: 71  SAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTL 130
            +VP  +P DTR L L  N++ +VP G       L+ LDL +N+L  L    F   +  L
Sbjct: 100 FSVPPDLPMDTRNLSLAHNRITAVPPGYLTCYMELQVLDLHNNSLMELPRGLFLHAK-RL 158

Query: 131 RHLDLSANQLASVPVEAFV---GLQIQVNLSANPW 162
            HLDLS N  + VP + F    GL + ++LS NPW
Sbjct: 159 AHLDLSYNNFSHVPADMFQEAHGL-VHIDLSHNPW 192



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 23/86 (26%)

Query: 91  LASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVG 150
           L  V   AFQ L  L +LDLS+  LA LS  A +GL G                      
Sbjct: 193 LRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGL--------------------- 231

Query: 151 LQIQVNLSANPWHCDCALQEVLRQVR 176
             + + +  NPW C C ++ +L+ +R
Sbjct: 232 --VTLQIGGNPWVCGCTMEPLLKWLR 255


>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
          Length = 653

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 39/104 (37%), Positives = 55/104 (52%), Gaps = 3/104 (2%)

Query: 45  PQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPV 104
           PQ  P  C  + +  +    C++ GLS VP GIP++TR L L  N +  + A  F+HL  
Sbjct: 43  PQNCPSVCSCSNQFSKVV--CTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHH 100

Query: 105 LEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
           LE L L  N++  +   AF GL  +L  L+L  N L  +P  AF
Sbjct: 101 LEVLQLGRNSIRQIEVGAFNGL-ASLNTLELFDNWLTVIPSGAF 143



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 9/122 (7%)

Query: 53  YVAKEAGERTFRCSQAGLSAVP-SGIPNDT-----RKLYLDANQLASVPAGAFQHLPVLE 106
           Y+++ A E  F      L       +PN T      +L +  N    +  G+F  L  L+
Sbjct: 186 YISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245

Query: 107 ELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSANPWHC 164
           +L + ++ ++ +   AF GL  +L  L+L+ N L+S+P + F  L+  ++++L  NPW+C
Sbjct: 246 KLWVMNSQVSLIERNAFDGL-ASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNC 304

Query: 165 DC 166
           DC
Sbjct: 305 DC 306



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 7/96 (7%)

Query: 70  LSAVPSGI---PNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSH-NALAHLSGAAFQG 125
           L+ +PSG     +  R+L+L  N + S+P+ AF  +P L  LDL     L ++S  AF+G
Sbjct: 135 LTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEG 194

Query: 126 LEGTLRHLDLSANQLASVP-VEAFVGLQIQVNLSAN 160
           L   L++L+L    +  +P +   VGL+ ++ +S N
Sbjct: 195 L-FNLKYLNLGMCNIKDMPNLTPLVGLE-ELEMSGN 228


>gi|41582239 immunoglobulin superfamily containing leucine-rich
           repeat [Homo sapiens]
          Length = 428

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 7/114 (6%)

Query: 28  HLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLD 87
           HLL   L++G     P P      C   ++ G +   C+   L +VP G P +   L L 
Sbjct: 5   HLLWWALLLGLAQACPEP------CDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 58

Query: 88  ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           AN+L  +P GAF+ +P+L+ L L+HN +  ++  A   L   L+ LDLS N ++
Sbjct: 59  ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASL-SHLKSLDLSHNLIS 111



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSAN 138
           L +D+N+L  +P  AF+ L  L  L L+HN L  L+   F  L   L HL ++ N
Sbjct: 127 LKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT-ALSHLQINEN 180


>gi|5031809 immunoglobulin superfamily containing leucine-rich
           repeat [Homo sapiens]
          Length = 428

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 7/114 (6%)

Query: 28  HLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLD 87
           HLL   L++G     P P      C   ++ G +   C+   L +VP G P +   L L 
Sbjct: 5   HLLWWALLLGLAQACPEP------CDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 58

Query: 88  ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           AN+L  +P GAF+ +P+L+ L L+HN +  ++  A   L   L+ LDLS N ++
Sbjct: 59  ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASL-SHLKSLDLSHNLIS 111



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSAN 138
           L +D+N+L  +P  AF+ L  L  L L+HN L  L+   F  L   L HL ++ N
Sbjct: 127 LKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT-ALSHLQINEN 180


>gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo
           sapiens]
          Length = 593

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 45/123 (36%), Positives = 60/123 (48%), Gaps = 9/123 (7%)

Query: 29  LLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDA 88
           L  LLL  G+GG+ P+       C    +   +   C    L AVP G+P DT  L L  
Sbjct: 18  LFLLLLPGGSGGSCPAV------CDCTSQP--QAVLCGHRQLEAVPGGLPLDTELLDLSG 69

Query: 89  NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
           N+L  +  G    L +L+ELDLS+N L+ L   AF GL+  L  L L  N+L  +    F
Sbjct: 70  NRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLT-LRLQGNRLRIMGPGVF 128

Query: 149 VGL 151
            GL
Sbjct: 129 SGL 131



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 3/94 (3%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R L L  N ++++PA     L  L+EL LS   L  ++  AF GL      LD++ N L 
Sbjct: 279 RVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLT-AFHLLDVADNALQ 337

Query: 142 SVPVEAFVGLQ--IQVNLSANPWHCDCALQEVLR 173
           ++   AF      + + LS NP  CDC L  +LR
Sbjct: 338 TLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLR 371



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 1/68 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  N+L  +  G F  L  L  LDL  N +      AF G  G+L+ L++  N L  V
Sbjct: 113 LRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAF-GELGSLQKLEVGDNHLVFV 171

Query: 144 PVEAFVGL 151
              AF GL
Sbjct: 172 APGAFAGL 179



 Score = 31.6 bits (70), Expect = 0.79
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 1/74 (1%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
           L L  NQ+     GAF  L  L++L++  N L  ++  AF GL   L  L L    L++V
Sbjct: 137 LDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGL-AKLSTLTLERCNLSTV 195

Query: 144 PVEAFVGLQIQVNL 157
           P  A   L   V L
Sbjct: 196 PGLALARLPALVAL 209



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 8/86 (9%)

Query: 84  LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSA-NQLAS 142
           L L+   L++VP  A   LP L  L L    +  L   A +GL G L+ L++     L +
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGL-GQLKELEIHLWPSLEA 243

Query: 143 VPVEAFVGLQI------QVNLSANPW 162
           +   + VGL +      + NLS+ P+
Sbjct: 244 LDPGSLVGLNLSSLAITRCNLSSVPF 269


>gi|5729718 trophoblast glycoprotein [Homo sapiens]
          Length = 420

 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 41/110 (37%), Positives = 51/110 (46%), Gaps = 29/110 (26%)

Query: 43  PSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGA---- 98
           P P   P  C  ++ A  RT +C    L+ VP+ +P   R L+L  NQLA +PAGA    
Sbjct: 57  PLPDQCPALCECSEAA--RTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARR 114

Query: 99  -----------------------FQHLPVLEELDLSHNALAHLSGAAFQG 125
                                  F+HLP L +LDLSHN LA LS  AF G
Sbjct: 115 PPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSG 164



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 8/106 (7%)

Query: 82  RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
           R+L L +N    +P      LP L  LDLS+N+L  L+  +F+ L   L  L L  N L 
Sbjct: 213 RRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLT-HLESLHLEDNALK 271

Query: 142 SVPVEAFVGLQ----IQVNLSANPWHCDCALQEV---LRQVRLVPG 180
            +       LQ    I+V L  NPW CDC + ++   L++  +V G
Sbjct: 272 VLHNGTLAELQGLPHIRVFLDNNPWVCDCHMADMVTWLKETEVVQG 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,207,706
Number of Sequences: 37866
Number of extensions: 561746
Number of successful extensions: 2750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 1575
Number of HSP's gapped (non-prelim): 822
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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