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Search of human proteins with 239751294
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751294 PREDICTED: similar to hCG2044133 [Homo sapiens]
(275 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756808 PREDICTED: similar to hCG2044133 [Homo sapiens] 554 e-158
gi|239751294 PREDICTED: similar to hCG2044133 [Homo sapiens] 554 e-158
gi|239745789 PREDICTED: hypothetical protein LOC728129 [Homo sap... 554 e-158
gi|13562088 leucine-rich repeat-containing 3 precursor [Homo sap... 168 4e-42
gi|16418445 leucine rich repeat containing 3B [Homo sapiens] 163 1e-40
gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom... 74 1e-13
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 74 2e-13
gi|88702793 slit-like 2 [Homo sapiens] 74 2e-13
gi|11321571 slit homolog 3 [Homo sapiens] 72 4e-13
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 72 5e-13
gi|194440719 chondroadherin-like [Homo sapiens] 72 7e-13
gi|59823631 G protein-coupled receptor 125 [Homo sapiens] 70 2e-12
gi|225579152 insulin-like growth factor binding protein, acid la... 70 2e-12
gi|4826772 insulin-like growth factor binding protein, acid labi... 70 2e-12
gi|188528675 slit homolog 1 [Homo sapiens] 69 3e-12
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 69 3e-12
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 67 2e-11
gi|4759146 slit homolog 2 [Homo sapiens] 67 2e-11
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 67 2e-11
gi|13194201 reticulon 4 receptor precursor [Homo sapiens] 66 3e-11
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 66 4e-11
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo... 65 6e-11
gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens] 65 8e-11
gi|61966761 leucine rich repeat containing 26 [Homo sapiens] 64 1e-10
gi|52353306 leucine rich repeat containing 55 [Homo sapiens] 64 1e-10
gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 62 4e-10
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 62 4e-10
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 62 4e-10
gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo... 62 5e-10
gi|5729718 trophoblast glycoprotein [Homo sapiens] 62 7e-10
>gi|239756808 PREDICTED: similar to hCG2044133 [Homo sapiens]
Length = 275
Score = 554 bits (1428), Expect = e-158
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
Sbjct: 1 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
Query: 61 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
Sbjct: 61 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
Query: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
Sbjct: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
Query: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
Sbjct: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
Query: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV
Sbjct: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
>gi|239751294 PREDICTED: similar to hCG2044133 [Homo sapiens]
Length = 275
Score = 554 bits (1428), Expect = e-158
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
Sbjct: 1 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
Query: 61 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
Sbjct: 61 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
Query: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
Sbjct: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
Query: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
Sbjct: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
Query: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV
Sbjct: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
>gi|239745789 PREDICTED: hypothetical protein LOC728129 [Homo
sapiens]
Length = 275
Score = 554 bits (1428), Expect = e-158
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE
Sbjct: 1 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 60
Query: 61 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG
Sbjct: 61 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 120
Query: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG
Sbjct: 121 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 180
Query: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL
Sbjct: 181 TGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYL 240
Query: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV
Sbjct: 241 VHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 275
>gi|13562088 leucine-rich repeat-containing 3 precursor [Homo
sapiens]
Length = 257
Score = 168 bits (426), Expect = 4e-42
Identities = 98/244 (40%), Positives = 136/244 (55%), Gaps = 11/244 (4%)
Query: 20 MAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPN 79
+ ++ T L LL + G P P C AG CS GL VP IP
Sbjct: 11 LLLVSTRESCLFLLFCLHLGAACPQP------CRCPDHAGAVAVFCSLRGLQEVPEDIPA 64
Query: 80 DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
+T L LDAN+++ +P GAFQHL L ELDLSHNA+ + A F GL G LR LDLS N+
Sbjct: 65 NTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLDLSYNR 124
Query: 140 LASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQE 199
+ +P +A L ++ LS NP HC+CALQE L +++L P + I C + + + VG+
Sbjct: 125 IQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEFVGKP 184
Query: 200 FL-LLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYLVHYVWQNRDETRRSLKRA 258
+ L LC R+TDVA+LVTM GW +++AY+V+YV N+++ RR L+
Sbjct: 185 LVQALDAGASLCSV----PHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEYL 240
Query: 259 PVLP 262
LP
Sbjct: 241 KSLP 244
>gi|16418445 leucine rich repeat containing 3B [Homo sapiens]
Length = 259
Score = 163 bits (413), Expect = 1e-40
Identities = 88/235 (37%), Positives = 138/235 (58%), Gaps = 8/235 (3%)
Query: 44 SPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLP 103
S + P+GC + +G CS A L +P +P +T LYLD+NQ+ S+P F+ L
Sbjct: 30 SASMCPKGC-LCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLH 88
Query: 104 VLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWH 163
L L+LS N + + AF+G+ TL+ LDLS N++ SV AF L+ + ++ NPWH
Sbjct: 89 QLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWH 148
Query: 164 CDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDV 223
CDC LQ+VLR + T ++C + + G+ FL A + +LC +++TD
Sbjct: 149 CDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNL----PKKTTDY 204
Query: 224 ALLVTMGGWLTLMVAYLVHYVWQNRDETRRSLKRAPVLPVR---SEDSSILSTVV 275
A+LVTM GW T++++Y+V+YV QN+++ RR L+ LP R +++ +STVV
Sbjct: 205 AMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV 259
>gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo
sapiens]
Length = 592
Score = 73.9 bits (180), Expect = 1e-13
Identities = 51/124 (41%), Positives = 64/124 (51%), Gaps = 10/124 (8%)
Query: 30 LPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERT--FRCSQAGLSAVPSGIPNDTRKLYLD 87
LPLLL+ P+ P GC E +T C++ L+AVP GIP +TR L L
Sbjct: 10 LPLLLL-------PAAPPPAGGCPARCECTVQTRAVACTRRRLTAVPDGIPAETRLLELS 62
Query: 88 ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEA 147
N++ + G LP LEELDLS NA+AH+ AF L LR L L NQL +P
Sbjct: 63 RNRIRCLNPGDLAALPALEELDLSENAIAHVEPGAFANLP-RLRVLRLRGNQLKLIPPGV 121
Query: 148 FVGL 151
F L
Sbjct: 122 FTRL 125
Score = 47.0 bits (110), Expect = 2e-05
Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N +++VP G+F+ L L EL L+ LA + AF GL +R L+LS N L+++
Sbjct: 275 LNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLR-QIRLLNLSNNLLSTL 333
Query: 144 PVEAF--VGLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGA 191
F V + + NP CDC L ++++ + + G C + A
Sbjct: 334 EESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPA 383
Score = 28.9 bits (63), Expect = 5.1
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L + N L V AF L LEEL L L LSG + L +L L L +A
Sbjct: 153 RRLEVGDNDLVFVSRRAFAGLLALEELTLERCNLTALSGESLGHLR-SLGALRLRHLAIA 211
Query: 142 SVPVEAFVGLQIQVNLSANPW 162
S+ + F L ++L + W
Sbjct: 212 SLEDQNFRRLPGLLHLEIDNW 232
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 73.6 bits (179), Expect = 2e-13
Identities = 44/105 (41%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Query: 43 PSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHL 102
P P P C+ ++ + CS+ GLSAVP + T L L N L + G F HL
Sbjct: 30 PGPTACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHL 89
Query: 103 PVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEA 147
LEEL LS N L+H+ G AF GL +L+ L L NQL +P EA
Sbjct: 90 RFLEELRLSGNHLSHIPGQAFSGLY-SLKILMLQNNQLGGIPAEA 133
Score = 47.0 bits (110), Expect = 2e-05
Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L NQL +PA A LP L+ L L N ++ + +F+GL +LRHL L N L +
Sbjct: 119 LMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL-SSLRHLWLDDNALTEI 177
Query: 144 PVEAFVGL 151
PV A L
Sbjct: 178 PVRALNNL 185
Score = 45.1 bits (105), Expect = 7e-05
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R L+LD N L +P A +LP L+ + L+ N ++H+ AFQ L +L L L N++
Sbjct: 165 RHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLT-SLVVLHLHNNRIQ 223
Query: 142 SVPVEAFVGLQIQVNLSAN 160
+ +F GL L N
Sbjct: 224 HLGTHSFEGLHNLETLDLN 242
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 86 LDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPV 145
L N++ + A F L L+ LDLS NA+ + AF L ++ LDL+ NQL ++P+
Sbjct: 381 LQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVK-LDLTDNQLTTLPL 439
Query: 146 EAFVGL 151
GL
Sbjct: 440 AGLGGL 445
Score = 37.4 bits (85), Expect = 0.014
Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
+ L LDAN ++ VP +F+ L L L L NAL + A L L+ + L+ N+++
Sbjct: 141 QSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP-ALQAMTLALNRIS 199
Query: 142 SVPVEAFVGL 151
+P AF L
Sbjct: 200 HIPDYAFQNL 209
Score = 36.6 bits (83), Expect = 0.024
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 22/87 (25%)
Query: 86 LDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLE------------------ 127
L N+++ +P AFQ+L L L L +N + HL +F+GL
Sbjct: 193 LALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA 252
Query: 128 ----GTLRHLDLSANQLASVPVEAFVG 150
G L+ L N + ++P +AF+G
Sbjct: 253 IRTLGRLQELGFHNNNIKAIPEKAFMG 279
Score = 32.0 bits (71), Expect = 0.60
Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 21/85 (24%)
Query: 94 VPAGAFQHLPVLEELDLSHNALAHLS---------------------GAAFQGLEGTLRH 132
+P+G Q LP L L+LSHN + L GA +L+
Sbjct: 343 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQA 402
Query: 133 LDLSANQLASVPVEAFVGLQIQVNL 157
LDLS N + S+ EAF L V L
Sbjct: 403 LDLSWNAIRSIHPEAFSTLHSLVKL 427
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 73.6 bits (179), Expect = 2e-13
Identities = 49/124 (39%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 29 LLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDA 88
LLPLLL++ G P Q P GC ++ +T C+ + VP +P DT LY+
Sbjct: 8 LLPLLLLLALG---PGVQGCPSGCQCSQP---QTVFCTARQGTTVPRDVPPDTVGLYVFE 61
Query: 89 NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
N + + AG+F LP L+ LDLS N +A L FQ L L +LDL+AN+L + E F
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPL-ANLSNLDLTANRLHEITNETF 120
Query: 149 VGLQ 152
GL+
Sbjct: 121 RGLR 124
Score = 28.9 bits (63), Expect = 5.1
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 83 KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
+LYL N++ + GAF L L EL L N L L L LDLS N L +
Sbjct: 128 RLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLP----RLLLLDLSHNSLLA 183
Query: 143 V 143
+
Sbjct: 184 L 184
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 72.4 bits (176), Expect = 4e-13
Identities = 53/159 (33%), Positives = 74/159 (46%), Gaps = 33/159 (20%)
Query: 39 GGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPA-- 96
G S Q+ PR C E RCS GL A+P G+P D +LYL+ N L +VP
Sbjct: 713 GNEESSCQLSPR-CPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPREL 771
Query: 97 GAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQI--- 153
A +HL ++ DLS+N+++ L+ F + L L LS N+L +PV AF GL+
Sbjct: 772 SALRHLTLI---DLSNNSISMLTNYTFSNMSH-LSTLILSYNRLRCIPVHAFNGLRSLRV 827
Query: 154 -----------------------QVNLSANPWHCDCALQ 169
+ L NP HCDC+L+
Sbjct: 828 LTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLR 866
Score = 60.5 bits (145), Expect = 2e-09
Identities = 50/169 (29%), Positives = 66/169 (39%), Gaps = 27/169 (15%)
Query: 32 LLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDT---------- 81
L L + + P P C + C GL AVP GIP +
Sbjct: 16 LALALALASVLSGP--PAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNI 73
Query: 82 --------------RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLE 127
R L+L+ NQ++ + GAFQ L LE L L+ N L L FQ
Sbjct: 74 TRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTP 133
Query: 128 GTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
L LDLS NQ+ +P +AF G+ NL + H C R +R
Sbjct: 134 -KLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALR 181
Score = 55.5 bits (132), Expect = 5e-08
Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 3/102 (2%)
Query: 65 CSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
C GL +P+ +P ++ L+ N + ++PAGAF L+ +D+S N ++ ++ AFQ
Sbjct: 293 CRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQ 352
Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGL-QIQ-VNLSANPWHC 164
GL+ +L L L N++ + F GL +Q + L+AN +C
Sbjct: 353 GLK-SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 393
Score = 48.1 bits (113), Expect = 8e-06
Identities = 40/133 (30%), Positives = 61/133 (45%), Gaps = 31/133 (23%)
Query: 77 IPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLS 136
+PN RK+ L N++ V GAF ++EL L+ N L + G F+GL G L+ L L
Sbjct: 556 LPN-LRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSG-LKTLMLR 613
Query: 137 ANQLASVPVEAFVGLQ--------------------------IQVNLSANPWHCDCALQ- 169
+N + V + F GL +NL +NP++C+C L
Sbjct: 614 SNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAW 673
Query: 170 --EVLRQVRLVPG 180
+ LR+ R+V G
Sbjct: 674 LGKWLRKRRIVSG 686
Score = 47.4 bits (111), Expect = 1e-05
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 65 CSQAGLSAVPSGIPNDTRKLYLDANQLASVPA-GAFQHLPVLEELDLSHNALAHLSGAAF 123
CS L +PS +P L L+ N+++ + A G F+ LP L +++LS+N + + AF
Sbjct: 518 CSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAF 577
Query: 124 QGLEGTLRHLDLSANQLASVPVEAFVGL 151
G +++ L L+ NQL +V F GL
Sbjct: 578 DG-AASVQELMLTGNQLETVHGRVFRGL 604
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N++ + G F L L+ L L+ N + L FQ L+ L L L N+L ++
Sbjct: 360 LVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQ-NLNLLSLYDNKLQTI 418
Query: 144 PVEAFVGLQ-IQ-VNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGAR 192
F LQ IQ ++L+ NP+ CDC L+ + ++ P +G C S R
Sbjct: 419 SKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRR 469
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 72.0 bits (175), Expect = 5e-13
Identities = 46/125 (36%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Query: 39 GGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGA 98
G PS PP G+R CS GL+AVP G+ T+ L + N + +P A
Sbjct: 17 GSAGPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDA 76
Query: 99 FQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLS 158
F++ P LEEL L+ N L+ + A GL+ L+ L L NQL +VP EA GL +L
Sbjct: 77 FKNFPFLEELQLAGNDLSFIHPKALSGLK-ELKVLTLQNNQLKTVPSEAIRGLSALQSLR 135
Query: 159 ANPWH 163
+ H
Sbjct: 136 LDANH 140
Score = 46.6 bits (109), Expect = 2e-05
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 83 KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
++ L NQ+ + G FQ L L LDLS N + + AF L G + +LD+S N+L S
Sbjct: 369 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATL-GPITNLDVSFNELTS 427
Query: 143 VPVEAFVGLQIQVNLSAN 160
P E GL Q+ L N
Sbjct: 428 FPTEGLNGLN-QLKLVGN 444
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 17/108 (15%)
Query: 69 GLSAVPS---------GIPNDT-------RKLYLDANQLASVPAGAFQHLPVLEELDLSH 112
GLSA+ S +P D+ R L+LD N L VP +LP L+ L L+
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186
Query: 113 NALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSAN 160
N ++ + AF L +L L L N++ S+ F GL L N
Sbjct: 187 NKISSIPDFAFTNL-SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLN 233
Score = 31.6 bits (70), Expect = 0.79
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L +++S+P Q +L LDLS+N + L +F G L + L NQ+ +
Sbjct: 324 LTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCH-ALEEISLQRNQIYQI 380
Query: 144 PVEAFVGL 151
F GL
Sbjct: 381 KEGTFQGL 388
Score = 31.2 bits (69), Expect = 1.0
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 5/57 (8%)
Query: 70 LSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGL 126
+ A+PS ++L +N ++ +P GAF P+L + L N L+ + +AF L
Sbjct: 244 IKALPS-----LKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNL 295
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 71.6 bits (174), Expect = 7e-13
Identities = 57/180 (31%), Positives = 82/180 (45%), Gaps = 31/180 (17%)
Query: 64 RCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAF 123
R ++ L A+ G + KL+LD NQL VP GA + LP L EL LS N L L AF
Sbjct: 556 RITEVSLGAL--GPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAF 613
Query: 124 QGLEGTLRHLDLSANQLASVPVEAFVGL------------------------QIQ-VNLS 158
Q + +L+HL L+++ L + AF GL Q++ ++LS
Sbjct: 614 QPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLS 673
Query: 159 ANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGAR 218
+NP+HCDC ++L R + G + P+ GQ A E C GW +
Sbjct: 674 SNPFHCDC---QLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDC-PGWAARK 729
Score = 65.9 bits (159), Expect = 4e-11
Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 49 PRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEEL 108
PR C E+ R C GL AVP G P+DT+ L L N SVP AF L L L
Sbjct: 397 PRACVCVPES--RHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSL 454
Query: 109 DLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVG 150
L H +A L A GL G L +L LS NQLA + A G
Sbjct: 455 HLQHCGIAELEAGALAGL-GRLIYLYLSDNQLAGLSAAALEG 495
Score = 65.1 bits (157), Expect = 6e-11
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 4/124 (3%)
Query: 29 LLPLL-LVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLD 87
+LPLL L++ + Q P+ C + R C L+ VP IP T++L L
Sbjct: 13 VLPLLVLLLLAPARQAAAQRCPQACIC--DNSRRHVACRYQNLTEVPDAIPELTQRLDLQ 70
Query: 88 ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEA 147
N L +PA AFQ +P L LDL H + ++ AF+GL G L L+L++N L +P EA
Sbjct: 71 GNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGL-GRLLLLNLASNHLRELPQEA 129
Query: 148 FVGL 151
GL
Sbjct: 130 LDGL 133
Score = 50.4 bits (119), Expect = 2e-06
Identities = 37/95 (38%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L L+ N L + G F L L L+L+HNAL +L AFQGL +R L LS N L+
Sbjct: 137 RRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLL-RVRWLRLSHNALS 195
Query: 142 SVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
+ EA GL LS + VL Q R
Sbjct: 196 VLAPEALAGLPALRRLSLHHNELQALPGPVLSQAR 230
Score = 40.4 bits (93), Expect = 0.002
Identities = 46/137 (33%), Positives = 57/137 (41%), Gaps = 29/137 (21%)
Query: 68 AGLSAVP-SGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNAL----------- 115
AGLSA G P LYL+ N+ VP A + LP L L L NA+
Sbjct: 486 AGLSAAALEGAPR-LGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRT 544
Query: 116 -----AHLSGAAFQ----GLEGTLRHLD---LSANQLASVPVEAFVGLQ--IQVNLSANP 161
+LSG G G R L+ L NQL VP A GL +++ LS NP
Sbjct: 545 RALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNP 604
Query: 162 WHC--DCALQEVLRQVR 176
D A Q V R ++
Sbjct: 605 LRALRDGAFQPVGRSLQ 621
Score = 39.3 bits (90), Expect = 0.004
Identities = 39/139 (28%), Positives = 54/139 (38%), Gaps = 28/139 (20%)
Query: 61 RTFRCSQAGLSAVP----SGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALA 116
R R S LS + +G+P R+L L N+L ++P L L+L HN L
Sbjct: 185 RWLRLSHNALSVLAPEALAGLPA-LRRLSLHHNELQALPGPVLSQARGLARLELGHNPLT 243
Query: 117 H----------------LSGAAFQGLEGT-------LRHLDLSANQLASVPVEAFVGLQI 153
+ L G A Q L L LDL NQL ++P G
Sbjct: 244 YAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLR 303
Query: 154 QVNLSANPWHCDCALQEVL 172
++ L NP C C + +L
Sbjct: 304 RLRLQGNPLWCGCQARPLL 322
>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
Length = 1321
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/158 (34%), Positives = 82/158 (51%), Gaps = 15/158 (9%)
Query: 15 GLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVP--------PRGCYVAKEAGERTFRCS 66
G Q +LP + LL LL ++G GG + +P PRG A A E CS
Sbjct: 9 GRAQPPLLLPLS--LLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCS 66
Query: 67 QAGLSAV--PSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
L+ V P +PN T L L N+++ + G+F L +LE LDL +N ++ + AF
Sbjct: 67 SLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFW 126
Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSAN 160
GL +L+ LDL+ N++ + + F GL +++NLS N
Sbjct: 127 GL-SSLKRLDLTNNRIGCLNADIFRGLTNLVRLNLSGN 163
>gi|225579152 insulin-like growth factor binding protein, acid
labile subunit isoform 1 precursor [Homo sapiens]
Length = 643
Score = 70.1 bits (170), Expect = 2e-12
Identities = 45/113 (39%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Query: 37 GTGGTVPSPQVPPRG-CYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVP 95
GT G P P C +A E + CS L+ +P G+P T+ L+LD N L+SVP
Sbjct: 69 GTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 128
Query: 96 AGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
AFQ+L L L+L L L A GLE L HL L NQL S+ + F
Sbjct: 129 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLE-NLCHLHLERNQLRSLALGTF 180
Score = 53.1 bits (126), Expect = 3e-07
Identities = 35/70 (50%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
+KLYLD N +A+V GAF L L LDLSHN +A L F GL G LR L LS N +A
Sbjct: 283 QKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLG-LRVLRLSHNAIA 341
Query: 142 SVPVEAFVGL 151
S+ F L
Sbjct: 342 SLRPRTFKDL 351
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/81 (43%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R L L N +AS+ F+ L LEEL L HN + L+ +F+GL G L L L NQL
Sbjct: 331 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGL-GQLEVLTLDHNQLQ 389
Query: 142 SVPVEAFVGLQ--IQVNLSAN 160
V AF+GL +NLS N
Sbjct: 390 EVKAGAFLGLTNVAVMNLSGN 410
Score = 49.3 bits (116), Expect = 4e-06
Identities = 31/71 (43%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L+L N L + + L L ELDL+ N L HL FQGL G L +L LS N+LA
Sbjct: 451 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGL-GKLEYLLLSRNRLA 509
Query: 142 SVPVEAFVGLQ 152
+P +A LQ
Sbjct: 510 ELPADALGPLQ 520
Score = 48.5 bits (114), Expect = 6e-06
Identities = 32/68 (47%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N LA +P AF+ L L EL L+ N LA+L A F GL LR LDLS N L ++
Sbjct: 213 LNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGL-AELRELDLSRNALRAI 271
Query: 144 PVEAFVGL 151
FV L
Sbjct: 272 KANVFVQL 279
Score = 48.1 bits (113), Expect = 8e-06
Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 80 DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
+ R+L L N L ++ A F LP L++L L N +A ++ AF GL+ LR LDLS N+
Sbjct: 257 ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLK-ALRWLDLSHNR 315
Query: 140 LASVPVEAFVGL 151
+A + + F GL
Sbjct: 316 VAGLLEDTFPGL 327
Score = 47.4 bits (111), Expect = 1e-05
Identities = 42/132 (31%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N+LA +PA A L LD+SHN L L + L G LR+L L N L +
Sbjct: 501 LLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPL-GRLRYLSLRNNSLRTF 559
Query: 144 PVEAFVGLQIQVNLSANPWHCDCALQEV----LRQVRLVPGTGTGIVCGSGARPDLVGQE 199
+ GL+ ++ L NPW C C L+ + L+ VP I G +P
Sbjct: 560 TPQP-PGLE-RLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYN 617
Query: 200 FLLLAGEEELCG 211
+ A E+ G
Sbjct: 618 NITCASPPEVVG 629
Score = 42.0 bits (97), Expect = 6e-04
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L L N+LA + F L L ELDLS NAL + F L L+ L L N +A
Sbjct: 235 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP-RLQKLYLDRNLIA 293
Query: 142 SVPVEAFVGLQ 152
+V AF+GL+
Sbjct: 294 AVAPGAFLGLK 304
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L LD NQL V AGAF L + ++LS N L +L F+GL G L L L + L +
Sbjct: 381 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGL-GKLHSLHLEGSCLGRI 439
Query: 144 PVEAFVGL 151
F GL
Sbjct: 440 RPHTFTGL 447
>gi|4826772 insulin-like growth factor binding protein, acid labile
subunit isoform 2 precursor [Homo sapiens]
Length = 605
Score = 70.1 bits (170), Expect = 2e-12
Identities = 45/113 (39%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Query: 37 GTGGTVPSPQVPPRG-CYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVP 95
GT G P P C +A E + CS L+ +P G+P T+ L+LD N L+SVP
Sbjct: 31 GTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 90
Query: 96 AGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
AFQ+L L L+L L L A GLE L HL L NQL S+ + F
Sbjct: 91 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLE-NLCHLHLERNQLRSLALGTF 142
Score = 53.1 bits (126), Expect = 3e-07
Identities = 35/70 (50%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
+KLYLD N +A+V GAF L L LDLSHN +A L F GL G LR L LS N +A
Sbjct: 245 QKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLG-LRVLRLSHNAIA 303
Query: 142 SVPVEAFVGL 151
S+ F L
Sbjct: 304 SLRPRTFKDL 313
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/81 (43%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R L L N +AS+ F+ L LEEL L HN + L+ +F+GL G L L L NQL
Sbjct: 293 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGL-GQLEVLTLDHNQLQ 351
Query: 142 SVPVEAFVGLQ--IQVNLSAN 160
V AF+GL +NLS N
Sbjct: 352 EVKAGAFLGLTNVAVMNLSGN 372
Score = 49.3 bits (116), Expect = 4e-06
Identities = 31/71 (43%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L+L N L + + L L ELDL+ N L HL FQGL G L +L LS N+LA
Sbjct: 413 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGL-GKLEYLLLSRNRLA 471
Query: 142 SVPVEAFVGLQ 152
+P +A LQ
Sbjct: 472 ELPADALGPLQ 482
Score = 48.5 bits (114), Expect = 6e-06
Identities = 32/68 (47%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N LA +P AF+ L L EL L+ N LA+L A F GL LR LDLS N L ++
Sbjct: 175 LNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGL-AELRELDLSRNALRAI 233
Query: 144 PVEAFVGL 151
FV L
Sbjct: 234 KANVFVQL 241
Score = 48.1 bits (113), Expect = 8e-06
Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 80 DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
+ R+L L N L ++ A F LP L++L L N +A ++ AF GL+ LR LDLS N+
Sbjct: 219 ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLK-ALRWLDLSHNR 277
Query: 140 LASVPVEAFVGL 151
+A + + F GL
Sbjct: 278 VAGLLEDTFPGL 289
Score = 47.4 bits (111), Expect = 1e-05
Identities = 42/132 (31%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N+LA +PA A L LD+SHN L L + L G LR+L L N L +
Sbjct: 463 LLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPL-GRLRYLSLRNNSLRTF 521
Query: 144 PVEAFVGLQIQVNLSANPWHCDCALQEV----LRQVRLVPGTGTGIVCGSGARPDLVGQE 199
+ GL+ ++ L NPW C C L+ + L+ VP I G +P
Sbjct: 522 TPQP-PGLE-RLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYN 579
Query: 200 FLLLAGEEELCG 211
+ A E+ G
Sbjct: 580 NITCASPPEVVG 591
Score = 42.0 bits (97), Expect = 6e-04
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L L N+LA + F L L ELDLS NAL + F L L+ L L N +A
Sbjct: 197 RELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP-RLQKLYLDRNLIA 255
Query: 142 SVPVEAFVGLQ 152
+V AF+GL+
Sbjct: 256 AVAPGAFLGLK 266
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L LD NQL V AGAF L + ++LS N L +L F+GL G L L L + L +
Sbjct: 343 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGL-GKLHSLHLEGSCLGRI 401
Query: 144 PVEAFVGL 151
F GL
Sbjct: 402 RPHTFTGL 409
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 69.3 bits (168), Expect = 3e-12
Identities = 50/157 (31%), Positives = 70/157 (44%), Gaps = 33/157 (21%)
Query: 39 GGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGA 98
GG +P PQ P + + RCS L A+P GIP + +LYLD NQ VP G
Sbjct: 726 GGCLPRPQCPQECACL-----DTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVP-GQ 779
Query: 99 FQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQI----- 153
L+ +DLS+N ++ LS ++F + L L LS N L +P AF GL+
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMS-QLTTLILSYNALQCIPPLAFQGLRSLRLLS 838
Query: 154 ---------------------QVNLSANPWHCDCALQ 169
+ + ANP +CDC L+
Sbjct: 839 LHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLR 875
Score = 65.5 bits (158), Expect = 5e-11
Identities = 54/205 (26%), Positives = 84/205 (40%), Gaps = 49/205 (23%)
Query: 37 GTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPA 96
G G VP+ + C C GL+A+P+ +P ++ L+ N + S+P
Sbjct: 267 GEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPP 326
Query: 97 GAFQHLPVLEELDLSHNALAHLSGAAFQGLEG-----------------------TLRHL 133
GAF L +DLS+N +A ++ AFQGL TL+ L
Sbjct: 327 GAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLL 386
Query: 134 DLSANQLASVPVEAFVGLQ-------------------------IQ-VNLSANPWHCDCA 167
L+AN++ + +AF LQ IQ ++L+ NP+ CDC
Sbjct: 387 LLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCN 446
Query: 168 LQEVLRQVRLVPGTGTGIVCGSGAR 192
L+ + +R P +G C S R
Sbjct: 447 LKWLADFLRTNPIETSGARCASPRR 471
Score = 54.3 bits (129), Expect = 1e-07
Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 25/139 (17%)
Query: 62 TFRCSQAGLSAVPSGIPNDTRKLYLDA------------------------NQLASVPAG 97
T C GL A+P IP +T +L L+ NQ+ +V G
Sbjct: 44 TVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERG 103
Query: 98 AFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNL 157
AF + LE L L+ N L L FQ + L LDLS N + ++P +AF G NL
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQ-ALSRLDLSENAIQAIPRKAFRGATDLKNL 162
Query: 158 SANPWHCDCALQEVLRQVR 176
+ C + R +R
Sbjct: 163 QLDKNQISCIEEGAFRALR 181
Score = 48.1 bits (113), Expect = 8e-06
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 55/170 (32%)
Query: 65 CSQAGLSAVPSGIPNDT-------------------------RKLYLDANQLASVPAGAF 99
CS L+ +P IP T +K+ L N+++ + GAF
Sbjct: 526 CSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAF 585
Query: 100 QHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQ------- 152
+ + EL L+ N L + F+GL+G LR L L N+++ + ++F GL+
Sbjct: 586 EGAASVSELHLTANQLESIRSGMFRGLDG-LRTLMLRNNRISCIHNDSFTGLRNVRLLSL 644
Query: 153 -------------------IQVNLSANPWHCDCALQEV---LRQVRLVPG 180
+NL ANP++C+C L + LR+ ++V G
Sbjct: 645 YDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTG 694
Score = 45.4 bits (106), Expect = 5e-05
Identities = 41/139 (29%), Positives = 62/139 (44%), Gaps = 6/139 (4%)
Query: 83 KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
+L L N + ++P AF+ L+ L L N ++ + AF+ L G L L L+ N + +
Sbjct: 137 RLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG-LEVLTLNNNNITT 195
Query: 143 VPVEAFVGLQ--IQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEF 200
+PV +F + L +N CDC L + + +R P G C A L G
Sbjct: 196 IPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPA--SLRGLNV 253
Query: 201 LLLAGEEELCGSGWGGARR 219
+ E C SG G A R
Sbjct: 254 AEVQKSEFSC-SGQGEAGR 271
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 69.3 bits (168), Expect = 3e-12
Identities = 44/114 (38%), Positives = 69/114 (60%), Gaps = 5/114 (4%)
Query: 49 PRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEEL 108
P CY ++ CSQ GL+ +PS +P TR L+L NQ+ +PA AF+ +P L L
Sbjct: 22 PDKCYC--QSSTNFVDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLMTL 79
Query: 109 DLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSAN 160
+LS+N+L++L+ AF GL+ L+ L+L+ N L S+ F L +++LS+N
Sbjct: 80 NLSNNSLSNLAPGAFHGLQ-HLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSN 132
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/90 (46%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R LYL NQLA + F HLP L+EL L N++ L A GL +L LDLS NQL
Sbjct: 125 RVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGL-SSLALLDLSRNQLG 183
Query: 142 SVPVEA---FVGLQIQVNLSANPWHCDCAL 168
++ EA LQ+ + L+ NPW CDCAL
Sbjct: 184 TISREALQPLASLQV-LRLTENPWRCDCAL 212
Score = 59.3 bits (142), Expect = 4e-09
Identities = 45/125 (36%), Positives = 60/125 (48%), Gaps = 13/125 (10%)
Query: 29 LLPLLLVIGTGGTVPSPQVPPR--GCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYL 86
LLPLLL++ +P R GC A T C L VP GIP T+ L+L
Sbjct: 8 LLPLLLLL----------LPLRAAGCPAACRCYSATVECGALRLRVVPLGIPPGTQTLFL 57
Query: 87 DANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVE 146
N +A + GA L L L L +N+L L AF+ + L L L++N+L +
Sbjct: 58 QDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRA-QPRLLELALTSNRLRGLRSG 116
Query: 147 AFVGL 151
AFVGL
Sbjct: 117 AFVGL 121
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 66.6 bits (161), Expect = 2e-11
Identities = 46/131 (35%), Positives = 63/131 (48%), Gaps = 26/131 (19%)
Query: 64 RCSQAGLSAVPSGIPNDTRKLYLDANQLASVP--AGAFQHLPVLE--------------- 106
RCS GL +P GIP D +LYLD NQ VP ++HL +++
Sbjct: 739 RCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFS 798
Query: 107 ------ELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLS-- 158
L LS+N L + F GL+ +LR L L N ++ VP AF L +L+
Sbjct: 799 NMTQLLTLILSYNRLRCIPPRTFDGLK-SLRLLSLHGNDISVVPEGAFNDLSALSHLAIG 857
Query: 159 ANPWHCDCALQ 169
ANP +CDC +Q
Sbjct: 858 ANPLYCDCNMQ 868
Score = 59.7 bits (143), Expect = 3e-09
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Query: 52 CYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLS 111
C A C GL+ +P+ +P ++ L+ N + +P GAF L +DLS
Sbjct: 273 CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLS 332
Query: 112 HNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGL-QIQ-VNLSANPWHC 164
+N ++ L+ AFQGL +L L L N++ +P F GL +Q + L+AN +C
Sbjct: 333 NNQISELAPDAFQGLR-SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386
Score = 53.5 bits (127), Expect = 2e-07
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 53/172 (30%)
Query: 62 TFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPA-GAFQHLPVLEELDLSHNALAHLSG 120
T CS L+ +P IP T +L L+ N+ + A G F+ LP L +++ S+N + +
Sbjct: 516 TVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEE 575
Query: 121 AAFQGLEG-----------------------TLRHLDLSANQLASVPVEAFVGLQI---- 153
AF+G G +L+ L L +N++ V ++F+GL
Sbjct: 576 GAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLL 635
Query: 154 ----------------------QVNLSANPWHCDCALQ---EVLRQVRLVPG 180
+NL ANP++C+C L E LR+ R+V G
Sbjct: 636 SLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTG 687
Score = 52.0 bits (123), Expect = 6e-07
Identities = 43/155 (27%), Positives = 61/155 (39%), Gaps = 25/155 (16%)
Query: 46 QVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDA----------------- 88
+V P+ C T C L +VP IP +T +L L+
Sbjct: 22 KVAPQACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHL 81
Query: 89 -------NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
N+++++ GAFQ L LE L L+ N L F G L LDLS NQ+
Sbjct: 82 RVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLG-TAKLYRLDLSENQIQ 140
Query: 142 SVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
++P +AF G NL + C R +R
Sbjct: 141 AIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Score = 38.5 bits (88), Expect = 0.006
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 80 DTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQ 139
D + L LD NQ++ + GAF+ L LE L L++N + LS A+F + LR L +N
Sbjct: 152 DIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMP-KLRTFRLHSNN 210
Query: 140 L 140
L
Sbjct: 211 L 211
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 66.6 bits (161), Expect = 2e-11
Identities = 51/155 (32%), Positives = 65/155 (41%), Gaps = 49/155 (31%)
Query: 65 CSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
CS GL+ VP +P TR L L N+L+++P+ AF +L L+ LDLS+N L L + F
Sbjct: 54 CSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFG 113
Query: 125 GLEG-----------------------TLRHLDLSANQLASVPVEAFVGLQIQVNLSA-- 159
L LRHLDLS N LA +P F GL +LS
Sbjct: 114 DLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRS 173
Query: 160 ------------------------NPWHCDCALQE 170
NPW CDC L+E
Sbjct: 174 NRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLRE 208
>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
Length = 473
Score = 66.2 bits (160), Expect = 3e-11
Identities = 46/140 (32%), Positives = 74/140 (52%), Gaps = 12/140 (8%)
Query: 77 IPNDTRK-------LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGT 129
+P+DT + L+L N+++SVP AF+ L L+ L L N +AH+ AF+ L G
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDL-GR 227
Query: 130 LRHLDLSANQLASVPVEAFVGLQI--QVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVC 187
L L L AN L+++P EA L+ + L+ NPW CDC + + ++ G+ + + C
Sbjct: 228 LMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPC 287
Query: 188 GSGARPDLVGQEFLLLAGEE 207
R L G++ LA +
Sbjct: 288 SLPQR--LAGRDLKRLAAND 305
Score = 65.9 bits (159), Expect = 4e-11
Identities = 50/126 (39%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 48 PPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEE 107
P G V + T C Q GL AVP GIP +++++L N+++ VPA +F+ L
Sbjct: 26 PCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTI 85
Query: 108 LDLSHNALAHLSGAAFQGLEGTLRHLDLSAN-QLASVPVEAFVGLQIQVNLSANPWHCD- 165
L L N LA + AAF GL L LDLS N QL SV F GL + H D
Sbjct: 86 LWLHSNVLARIDAAAFTGL-ALLEQLDLSDNAQLRSVDPATFHGLG-----RLHTLHLDR 139
Query: 166 CALQEV 171
C LQE+
Sbjct: 140 CGLQEL 145
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/68 (42%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L+LD L + G F+ L L+ L L NAL L F+ L G L HL L N+++SV
Sbjct: 135 LHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDL-GNLTHLFLHGNRISSV 193
Query: 144 PVEAFVGL 151
P AF GL
Sbjct: 194 PERAFRGL 201
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 65.9 bits (159), Expect = 4e-11
Identities = 51/139 (36%), Positives = 68/139 (48%), Gaps = 6/139 (4%)
Query: 30 LPLLLVIGTGGTVPSPQVPPRGCYV---AKEAGERTFR--CSQAGLSAVPSGIPNDTRKL 84
LP+LL + TGG+ P V RGC + G R CS GLS +PS + T L
Sbjct: 12 LPVLLQLATGGSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYL 71
Query: 85 YLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVP 144
L N ++ + L LEEL L+ NAL ++ AF GL +L+ L L NQL VP
Sbjct: 72 DLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY-SLKVLMLQNNQLRHVP 130
Query: 145 VEAFVGLQIQVNLSANPWH 163
EA L+ +L + H
Sbjct: 131 TEALQNLRSLQSLRLDANH 149
Score = 41.6 bits (96), Expect = 8e-04
Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Query: 61 RTFRCSQAGLSAVP----SGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALA 116
++ R +S VP SG+ + R L+LD N L +P AF+ L L+ + L+ N +
Sbjct: 141 QSLRLDANHISYVPPSCFSGL-HSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIH 199
Query: 117 HLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSAN 160
H+ AF L +L L L N++ S+ + F GL L N
Sbjct: 200 HIPDYAFGNL-SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Score = 39.3 bits (90), Expect = 0.004
Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
+K+ L N++ + FQ L L L+L+ N +A + AF L ++ LDLS+N L+
Sbjct: 377 QKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIK-LDLSSNLLS 435
Query: 142 SVPVEAFVGL 151
S P+ GL
Sbjct: 436 SFPITGLHGL 445
Score = 35.8 bits (81), Expect = 0.042
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Query: 68 AGLSAVPSGIPNDTRKLY---LDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
A +S++P + N L L N L +P+ F L+++DL HN + + FQ
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQ 395
Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSAN 160
L +LR L+L+ N++A + AF L I+++LS+N
Sbjct: 396 QLL-SLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSN 432
Score = 35.4 bits (80), Expect = 0.054
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L+L N++ S+ F L LE LDL++N L A + L L+ L +N + S+
Sbjct: 215 LHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP-TAIRTLSN-LKELGFHSNNIRSI 272
Query: 144 PVEAFVG 150
P +AFVG
Sbjct: 273 PEKAFVG 279
Score = 33.1 bits (74), Expect = 0.27
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L Q++S+P LP L+ LDLS+N L L + + L+ +DL N++ +
Sbjct: 333 LTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFS---VCQKLQKIDLRHNEIYEI 389
Query: 144 PVEAF 148
V+ F
Sbjct: 390 KVDTF 394
Score = 28.9 bits (63), Expect = 5.1
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 89 NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGT--LRHLDLSANQLASVP 144
N + V AFQHLP L L L N + ++ F L GT L L L+ Q++S+P
Sbjct: 291 NPIQFVGRSAFQHLPELRTLTL--NGASQIT--EFPDLTGTANLESLTLTGAQISSLP 344
>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
sapiens]
Length = 606
Score = 65.1 bits (157), Expect = 6e-11
Identities = 39/94 (41%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Query: 58 AGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAH 117
A ++ C + L A+P GIP +T+ L L N+L SV F P+LEE+DLS N +A+
Sbjct: 36 AQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIAN 95
Query: 118 LSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGL 151
+ AF L LR L L N+L VP+ F GL
Sbjct: 96 VEPGAFNNL-FNLRSLRLKGNRLKLVPLGVFTGL 128
Score = 42.4 bits (98), Expect = 4e-04
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R L L N+L VP G F L L +LD+S N + L FQ L L+ L++ N L
Sbjct: 108 RSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLH-NLKSLEVGDNDLV 166
Query: 142 SVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVR 176
+ AF GL L+ + E L +R
Sbjct: 167 YISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLR 201
Score = 42.0 bits (97), Expect = 6e-04
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N ++++ AG F L L+EL + L + +FQGL LR L++S N L ++
Sbjct: 278 LNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR-FLRVLNVSQNLLETL 336
Query: 144 PVEAFV---GLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLV 196
F L++ ++++ NP CDC L +L++ + G +C A PD +
Sbjct: 337 EENVFSSPRALEV-LSINNNPLACDCRLLWILQRQPTLQFGGQQPMC---AGPDTI 388
Score = 28.9 bits (63), Expect = 5.1
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 83 KLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLAS 142
+L L+ L +VP A HL L L L H + ++ AF+ L L+HL++ L
Sbjct: 181 QLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRL-FHLKHLEIDYWPLLD 239
Query: 143 -VPVEAFVGLQI------QVNLSANPW 162
+P + GL + NLS P+
Sbjct: 240 MMPANSLYGLNLTSLSVTNTNLSTVPF 266
>gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens]
Length = 620
Score = 64.7 bits (156), Expect = 8e-11
Identities = 44/120 (36%), Positives = 65/120 (54%), Gaps = 4/120 (3%)
Query: 32 LLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQL 91
LLLV+G+ + + PPR C + A +R C + AVP GIP +TR L L N++
Sbjct: 27 LLLVLGSVLSGSATGCPPR-CECS--AQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRI 83
Query: 92 ASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGL 151
++ F P LEEL+L+ N ++ + AF L LR L L +N+L +P+ F GL
Sbjct: 84 KTLNQDEFASFPHLEELELNENIVSAVEPGAFNNL-FNLRTLGLRSNRLKLIPLGVFTGL 142
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R L L N ++++ L L+E+ L LA + AF+GL LR L++S NQL
Sbjct: 290 RFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGL-NYLRVLNVSGNQLT 348
Query: 142 SVPVEAF--VGLQIQVNLSANPWHCDCALQEVLRQ 174
++ F VG + L +NP CDC L V R+
Sbjct: 349 TLEESVFHSVGNLETLILDSNPLACDCRLLWVFRR 383
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 70 LSAVPSGIPNDT---RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGL 126
+SAV G N+ R L L +N+L +P G F L L +LD+S N + L FQ L
Sbjct: 107 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 166
Query: 127 EGTLRHLDLSANQLASVPVEAFVGL 151
L+ L++ N L + AF GL
Sbjct: 167 Y-NLKSLEVGDNDLVYISHRAFSGL 190
>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
Length = 334
Score = 64.3 bits (155), Expect = 1e-10
Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 65 CSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQ 124
CS L AVP G+ R L LD N++ ++P GAF L+ LDL N L + AF
Sbjct: 57 CSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFW 116
Query: 125 GLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLS 158
GL G L+ LDLSANQL ++ F L+ NLS
Sbjct: 117 GL-GALQLLDLSANQLEALAPGTFAPLRALRNLS 149
Score = 51.6 bits (122), Expect = 7e-07
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L ANQL ++ G F L L L L+ N LA L AA L LR L L N+LA++
Sbjct: 124 LDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALP-LLRSLSLQDNELAAL 182
Query: 144 PVEAFVGLQI--QVNLSANPWHCDCALQEVLRQVRLVP 179
L ++L NPW C CAL+ + +R P
Sbjct: 183 APGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHP 220
>gi|52353306 leucine rich repeat containing 55 [Homo sapiens]
Length = 341
Score = 63.9 bits (154), Expect = 1e-10
Identities = 52/155 (33%), Positives = 71/155 (45%), Gaps = 10/155 (6%)
Query: 14 PGLCQFMAMLPTAGHLLPLLLVIG---TGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGL 70
P + A LP G P +L+I G + S C V + CS L
Sbjct: 42 PKMGDTWAQLPWPGPPHPAMLLISLLLAAGLMHSDA--GTSCPVLCTCRNQVVDCSSQRL 99
Query: 71 SAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTL 130
+VP +P DTR L L N++ +VP G L+ LDL +N+L L F + L
Sbjct: 100 FSVPPDLPMDTRNLSLAHNRITAVPPGYLTCYMELQVLDLHNNSLMELPRGLFLHAK-RL 158
Query: 131 RHLDLSANQLASVPVEAFV---GLQIQVNLSANPW 162
HLDLS N + VP + F GL + ++LS NPW
Sbjct: 159 AHLDLSYNNFSHVPADMFQEAHGL-VHIDLSHNPW 192
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 23/86 (26%)
Query: 91 LASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVG 150
L V AFQ L L +LDLS+ LA LS A +GL G
Sbjct: 193 LRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGL--------------------- 231
Query: 151 LQIQVNLSANPWHCDCALQEVLRQVR 176
+ + + NPW C C ++ +L+ +R
Sbjct: 232 --VTLQIGGNPWVCGCTMEPLLKWLR 255
>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
Length = 653
Score = 62.4 bits (150), Expect = 4e-10
Identities = 39/104 (37%), Positives = 55/104 (52%), Gaps = 3/104 (2%)
Query: 45 PQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPV 104
PQ P C + + + C++ GLS VP GIP++TR L L N + + A F+HL
Sbjct: 43 PQNCPSVCSCSNQFSKVV--CTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHH 100
Query: 105 LEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
LE L L N++ + AF GL +L L+L N L +P AF
Sbjct: 101 LEVLQLGRNSIRQIEVGAFNGL-ASLNTLELFDNWLTVIPSGAF 143
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 9/122 (7%)
Query: 53 YVAKEAGERTFRCSQAGLSAVP-SGIPNDT-----RKLYLDANQLASVPAGAFQHLPVLE 106
Y+++ A E F L +PN T +L + N + G+F L L+
Sbjct: 186 YISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245
Query: 107 ELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQ--IQVNLSANPWHC 164
+L + ++ ++ + AF GL +L L+L+ N L+S+P + F L+ ++++L NPW+C
Sbjct: 246 KLWVMNSQVSLIERNAFDGL-ASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNC 304
Query: 165 DC 166
DC
Sbjct: 305 DC 306
Score = 42.7 bits (99), Expect = 3e-04
Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 7/96 (7%)
Query: 70 LSAVPSGI---PNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSH-NALAHLSGAAFQG 125
L+ +PSG + R+L+L N + S+P+ AF +P L LDL L ++S AF+G
Sbjct: 135 LTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEG 194
Query: 126 LEGTLRHLDLSANQLASVP-VEAFVGLQIQVNLSAN 160
L L++L+L + +P + VGL+ ++ +S N
Sbjct: 195 L-FNLKYLNLGMCNIKDMPNLTPLVGLE-ELEMSGN 228
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 62.4 bits (150), Expect = 4e-10
Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 7/114 (6%)
Query: 28 HLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLD 87
HLL L++G P P C ++ G + C+ L +VP G P + L L
Sbjct: 5 HLLWWALLLGLAQACPEP------CDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 58
Query: 88 ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
AN+L +P GAF+ +P+L+ L L+HN + ++ A L L+ LDLS N ++
Sbjct: 59 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASL-SHLKSLDLSHNLIS 111
Score = 38.1 bits (87), Expect = 0.008
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSAN 138
L +D+N+L +P AF+ L L L L+HN L L+ F L L HL ++ N
Sbjct: 127 LKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT-ALSHLQINEN 180
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 62.4 bits (150), Expect = 4e-10
Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 7/114 (6%)
Query: 28 HLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLD 87
HLL L++G P P C ++ G + C+ L +VP G P + L L
Sbjct: 5 HLLWWALLLGLAQACPEP------CDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 58
Query: 88 ANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
AN+L +P GAF+ +P+L+ L L+HN + ++ A L L+ LDLS N ++
Sbjct: 59 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASL-SHLKSLDLSHNLIS 111
Score = 38.1 bits (87), Expect = 0.008
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSAN 138
L +D+N+L +P AF+ L L L L+HN L L+ F L L HL ++ N
Sbjct: 127 LKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT-ALSHLQINEN 180
>gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo
sapiens]
Length = 593
Score = 62.0 bits (149), Expect = 5e-10
Identities = 45/123 (36%), Positives = 60/123 (48%), Gaps = 9/123 (7%)
Query: 29 LLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDA 88
L LLL G+GG+ P+ C + + C L AVP G+P DT L L
Sbjct: 18 LFLLLLPGGSGGSCPAV------CDCTSQP--QAVLCGHRQLEAVPGGLPLDTELLDLSG 69
Query: 89 NQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAF 148
N+L + G L +L+ELDLS+N L+ L AF GL+ L L L N+L + F
Sbjct: 70 NRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLT-LRLQGNRLRIMGPGVF 128
Query: 149 VGL 151
GL
Sbjct: 129 SGL 131
Score = 46.6 bits (109), Expect = 2e-05
Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R L L N ++++PA L L+EL LS L ++ AF GL LD++ N L
Sbjct: 279 RVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLT-AFHLLDVADNALQ 337
Query: 142 SVPVEAFVGLQ--IQVNLSANPWHCDCALQEVLR 173
++ AF + + LS NP CDC L +LR
Sbjct: 338 TLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLR 371
Score = 34.3 bits (77), Expect = 0.12
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L N+L + G F L L LDL N + AF G G+L+ L++ N L V
Sbjct: 113 LRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAF-GELGSLQKLEVGDNHLVFV 171
Query: 144 PVEAFVGL 151
AF GL
Sbjct: 172 APGAFAGL 179
Score = 31.6 bits (70), Expect = 0.79
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASV 143
L L NQ+ GAF L L++L++ N L ++ AF GL L L L L++V
Sbjct: 137 LDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGL-AKLSTLTLERCNLSTV 195
Query: 144 PVEAFVGLQIQVNL 157
P A L V L
Sbjct: 196 PGLALARLPALVAL 209
Score = 28.9 bits (63), Expect = 5.1
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 8/86 (9%)
Query: 84 LYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSA-NQLAS 142
L L+ L++VP A LP L L L + L A +GL G L+ L++ L +
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGL-GQLKELEIHLWPSLEA 243
Query: 143 VPVEAFVGLQI------QVNLSANPW 162
+ + VGL + + NLS+ P+
Sbjct: 244 LDPGSLVGLNLSSLAITRCNLSSVPF 269
>gi|5729718 trophoblast glycoprotein [Homo sapiens]
Length = 420
Score = 61.6 bits (148), Expect = 7e-10
Identities = 41/110 (37%), Positives = 51/110 (46%), Gaps = 29/110 (26%)
Query: 43 PSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGA---- 98
P P P C ++ A RT +C L+ VP+ +P R L+L NQLA +PAGA
Sbjct: 57 PLPDQCPALCECSEAA--RTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARR 114
Query: 99 -----------------------FQHLPVLEELDLSHNALAHLSGAAFQG 125
F+HLP L +LDLSHN LA LS AF G
Sbjct: 115 PPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSG 164
Score = 50.8 bits (120), Expect = 1e-06
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 8/106 (7%)
Query: 82 RKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLA 141
R+L L +N +P LP L LDLS+N+L L+ +F+ L L L L N L
Sbjct: 213 RRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLT-HLESLHLEDNALK 271
Query: 142 SVPVEAFVGLQ----IQVNLSANPWHCDCALQEV---LRQVRLVPG 180
+ LQ I+V L NPW CDC + ++ L++ +V G
Sbjct: 272 VLHNGTLAELQGLPHIRVFLDNNPWVCDCHMADMVTWLKETEVVQG 317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,207,706
Number of Sequences: 37866
Number of extensions: 561746
Number of successful extensions: 2750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 1575
Number of HSP's gapped (non-prelim): 822
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.