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Search of human proteins with 239749596
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo
sapiens]
(853 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo ... 1922 0.0
gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo ... 1920 0.0
gi|239755070 PREDICTED: similar to proprotein convertase subtili... 1911 0.0
gi|108773804 Fraser syndrome 1 [Homo sapiens] 313 4e-85
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 156 7e-38
gi|4505577 paired basic amino acid cleaving system 4 isoform a p... 141 3e-33
gi|20336180 paired basic amino acid cleaving system 4 isoform b ... 141 3e-33
gi|20336184 paired basic amino acid cleaving system 4 isoform h ... 137 3e-32
gi|20336182 paired basic amino acid cleaving system 4 isoform g ... 137 6e-32
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 128 3e-29
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 116 8e-26
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 109 9e-24
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 107 4e-23
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 90 8e-18
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 90 8e-18
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 77 9e-14
gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Ho... 76 2e-13
gi|143770880 laminin, beta 4 [Homo sapiens] 75 2e-13
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 75 3e-13
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 75 3e-13
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 69 1e-11
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 69 2e-11
gi|84490388 R-spondin1 [Homo sapiens] 67 9e-11
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 66 1e-10
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 66 1e-10
gi|29725609 epidermal growth factor receptor isoform a precursor... 65 3e-10
gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homo... 65 3e-10
gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolo... 65 3e-10
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 63 1e-09
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 63 1e-09
>gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo
sapiens]
Length = 853
Score = 1922 bits (4979), Expect = 0.0
Identities = 853/853 (100%), Positives = 853/853 (100%)
Query: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC
Sbjct: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
Query: 61 YKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
YKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE
Sbjct: 61 YKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC
Sbjct: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC
Sbjct: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV
Sbjct: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
Query: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH
Sbjct: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
Query: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT
Sbjct: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
Query: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ
Sbjct: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
Query: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK
Sbjct: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
Query: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH
Sbjct: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
Query: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN
Sbjct: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
Query: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC
Sbjct: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
Query: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK
Sbjct: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
Query: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID
Sbjct: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
Query: 841 ELEYDDESYSYYQ 853
ELEYDDESYSYYQ
Sbjct: 841 ELEYDDESYSYYQ 853
>gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo
sapiens]
Length = 853
Score = 1920 bits (4974), Expect = 0.0
Identities = 852/853 (99%), Positives = 852/853 (99%)
Query: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC
Sbjct: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
Query: 61 YKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
YKTCPEKTYSE VECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE
Sbjct: 61 YKTCPEKTYSEEVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC
Sbjct: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC
Sbjct: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV
Sbjct: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
Query: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH
Sbjct: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
Query: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT
Sbjct: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
Query: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ
Sbjct: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
Query: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK
Sbjct: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
Query: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH
Sbjct: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
Query: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN
Sbjct: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
Query: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC
Sbjct: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
Query: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK
Sbjct: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
Query: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID
Sbjct: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
Query: 841 ELEYDDESYSYYQ 853
ELEYDDESYSYYQ
Sbjct: 841 ELEYDDESYSYYQ 853
>gi|239755070 PREDICTED: similar to proprotein convertase
subtilisin/kexin type 5 [Homo sapiens]
Length = 853
Score = 1911 bits (4951), Expect = 0.0
Identities = 847/853 (99%), Positives = 850/853 (99%)
Query: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC
Sbjct: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
Query: 61 YKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
YKTCPEKTYSEAVECKACDSNC SCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE
Sbjct: 61 YKTCPEKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC
Sbjct: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC
Sbjct: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV
Sbjct: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
Query: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
CQENCPERHVAV+GVCKHCPEMCQDCIHEKTCKEC PEFFLHDDMCHQSCPRGFYADS H
Sbjct: 301 CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHH 360
Query: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK+TKECRDCHKSCLT
Sbjct: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLT 420
Query: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ
Sbjct: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
Query: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK
Sbjct: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
Query: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH
Sbjct: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
Query: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN
Sbjct: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
Query: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CEKCHESCMECKGPGAKNCTLCPANLVLHMD+SHCLHCCNTSDPPSAQECCDCQDTTDEC
Sbjct: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDEC 720
Query: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK
Sbjct: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
Query: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID
Sbjct: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
Query: 841 ELEYDDESYSYYQ 853
ELEYDDESYSYYQ
Sbjct: 841 ELEYDDESYSYYQ 853
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 313 bits (802), Expect = 4e-85
Identities = 203/667 (30%), Positives = 281/667 (42%), Gaps = 61/667 (9%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQN-GCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C +C Y C AC C +C C C+ + G CV CG GFY D+
Sbjct: 450 CVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDRH- 508
Query: 119 GECESCHRACETCTGPGHDECSSCQEGLQLLR-GMCVHATKTQEEGKFWNDILRKLQPCH 177
C CH +C C GP C +C++ L +LR G C + GK + + C
Sbjct: 509 -SCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSC-----GKGFYNRQGTCSACD 562
Query: 178 SSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGA--D 235
SC +C S+ C +C + L C+S CP G + +G C+ C +CA CSG
Sbjct: 563 QSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADA-TGRCKVCHNSCASCSGPTPS 621
Query: 236 LCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNA-TNCHSC---- 290
C C P L +G C +C EG Y++ G+C+ C S C C G A ++C C
Sbjct: 622 HCTACSP----PKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPE 677
Query: 291 EGGHV-------LHHGVCQENCPER-HVAVKGVCKHCPEMCQDCIHEK--TCKECTPEFF 340
EG V + G C C ++ G+C+ C + C C + C +C P
Sbjct: 678 EGLQVEQLSDVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKSPHNCTDCGPSHV 737
Query: 341 LHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPA 400
L D C CP G++ C CH C +C GP DC C L +G C C
Sbjct: 738 LLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHI-SLTNGNCRTSCRE 796
Query: 401 GTYYEKETKECRDCHKSCLTCSSS-----GTCTTCQKGLIMNPRGSCMANEKCSPSEYWD 455
+ C DCH C C++ C CQ + C+ + PS Y+
Sbjct: 797 EQFLNL-VGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPD---CPSGYYA 852
Query: 456 EDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNT-TCVKDCPEGYYADEDSNRCAHCH 514
E CK CH C C G C +C N +L +T TC C G+Y D D++ C C+
Sbjct: 853 ERG-ACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLD-DNHVCQPCN 910
Query: 515 SSCRTCEGRHSRQCHSCR-PGWFQLGKECLLQ-CREGYYADNSTGRCERCNRSCKGCQGP 572
+ C +C+ + S C SCR P L EC + C YY D ST C+ C+ SC C GP
Sbjct: 911 THCGSCDSQAS--CTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGP 968
Query: 573 RPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCV 632
TDCL C + L G C C +Y Q + C +C C QC+G C C
Sbjct: 969 LKTDCLQCMDGYVL--QDGACVEQCLSSFY--QDSGLC-KCDSYCLQCQGPH--ECTRCK 1021
Query: 633 WSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDD 692
+ L+ C +C G + + K C C + C++C C LC L
Sbjct: 1022 GPFLLLEAQCVQECGKGYF--ADHAKHKCTACPQGCLQCS--HRDRCHLCDHGFFL--KS 1075
Query: 693 SHCLHCC 699
C++ C
Sbjct: 1076 GLCVYNC 1082
Score = 305 bits (781), Expect = 1e-82
Identities = 181/616 (29%), Positives = 271/616 (43%), Gaps = 51/616 (8%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSC---DQNGCYWCEEGFFLL-GGSCVRKCGPGFYGD 115
C TC + Y + C C +C C + C C + +L G C CG GFY
Sbjct: 495 CVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNR 554
Query: 116 QEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQP 175
Q G C +C ++C++C GP C +C E L G C+ ++ G ++ D + +
Sbjct: 555 Q--GTCSACDQSCDSC-GPSSPRCLTCTEKTVLHDGKCM----SECPGGYYADATGRCKV 607
Query: 176 CHSSCKTCNG-SATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG- 233
CH+SC +C+G + + CT+C L C+ C +G + G C+ C +C C G
Sbjct: 608 CHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSD--HGVCKACHSSCLACMGP 665
Query: 234 ----ADLCKK----CQMQPGHPLFLHEGRCYSKCPEGSYAED-GICERCSSPCRTCEGNA 284
CKK Q++ + + G C ++C Y E GICE C C C G +
Sbjct: 666 APSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKS 725
Query: 285 T-NCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIH--EKTCKECTPEFFL 341
NC C HVL G C CP+ + +G C C C+ C E C C P L
Sbjct: 726 PHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISL 785
Query: 342 HDDMCHQSCPRGFYADS-RHCVPCHKDCLECSGPKADDCELCLE---SSWVLYDGLCLEE 397
+ C SC + + +C CH C C+ + +CL + ++L C+ +
Sbjct: 786 TNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPD 845
Query: 398 CPAGTYYEKETKECRDCHKSCLTCSSSG--TCTTCQKGLIMNPRGSCMANEKCSPSEYWD 455
CP+G Y E+ C+ CH SC TC G +C++C L+++ G+C C P Y D
Sbjct: 846 CPSGYYAERGA--CKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTT--CFPGHYLD 901
Query: 456 EDAPGCKPCHVKCFHCMGPAEDQCQTC--PMNSLLLNTTCVKDCPEGYYADEDSNRCAHC 513
++ C+PC+ C C ++ C +C P LL + C YY D +N C C
Sbjct: 902 DNHV-CQPCNTHCGSC--DSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKEC 958
Query: 514 HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPR 573
SC C G C C G+ C+ QC +Y D +G C +C+ C CQGP
Sbjct: 959 DWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQD--SGLC-KCDSYCLQCQGPH 1015
Query: 574 PTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVW 633
+C C F LL + +C + C Y+ + + C C C QC + C C
Sbjct: 1016 --ECTRCKGPFLLL--EAQCVQECGKGYFADHAKHKCTACPQGCLQCSHRD--RCHLCDH 1069
Query: 634 SYHLMGGICTSDCLVG 649
+ L G+C +C+ G
Sbjct: 1070 GFFLKSGLCVYNCVPG 1085
Score = 298 bits (763), Expect = 1e-80
Identities = 176/576 (30%), Positives = 261/576 (45%), Gaps = 42/576 (7%)
Query: 57 DHHCYKTCPEKTYSEAVECKACDSNCGSCDQNG--CYWCEEGFFLLGGSCVRKCGPGFYG 114
D C +C + Y+ C ACD +C SC + C C E L G C+ +C G+Y
Sbjct: 540 DGGCESSCGKGFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYA 599
Query: 115 DQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQ 174
D G C+ CH +C +C+GP C++C L +G C+ EG F++D +
Sbjct: 600 D-ATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRC---GEG-FYSD-HGVCK 653
Query: 175 PCHSSCKTCNGSA-TLCTSCPK-----------GAYLLAQACVSSCPQGTWPSVRSGSCE 222
CHSSC C G A + CT C K + + C++ C + + +G CE
Sbjct: 654 ACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQC-RAHFYLESTGICE 712
Query: 223 NCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEG 282
C ++C C+G P H L +G+C S+CP+G + ++G C C CR C G
Sbjct: 713 ACHQSCFRCAGKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEGSCTECHPTCRQCHG 770
Query: 283 N-ATNCHSCEGGHVLHHGVCQENC-PERHVAVKGVCKHCPEMCQDCIHE-----KTCKEC 335
++C SC L +G C+ +C E+ + + G C C +CQ C + C C
Sbjct: 771 PLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNTGSICLRC 830
Query: 336 -TPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLC 394
+ L D C CP G+YA+ C CH C C G C C + + + G C
Sbjct: 831 QNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTC 890
Query: 395 LEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
C G Y + + C+ C+ C +C S +CT+C+ + G C E C+P Y
Sbjct: 891 STTCFPGHYLD-DNHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQ-YESCAPQYYL 948
Query: 455 DEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH 514
D CK C C C GP + C C +L + CV+ C +Y +DS C C
Sbjct: 949 DFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFY--QDSGLC-KCD 1005
Query: 515 SSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRP 574
S C C+G H +C C+ + L +C+ +C +GY+AD++ +C C + C C
Sbjct: 1006 SYCLQCQGPH--ECTRCKGPFLLLEAQCVQECGKGYFADHAKHKCTACPQGCLQCS--HR 1061
Query: 575 TDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTC 610
C CD FFL G C +C + V S +TC
Sbjct: 1062 DRCHLCDHGFFL--KSGLCVYNCVPGFSVHTSNETC 1095
Score = 286 bits (732), Expect = 6e-77
Identities = 210/740 (28%), Positives = 280/740 (37%), Gaps = 165/740 (22%)
Query: 82 CGSC-DQNG-CYWCEEGFFLLGGSCVRKCGPGFYGDQ-EMGECE--SCHRACETCTGPGH 136
C C +NG C + E G F+ + K P G++ E G C+ C A TC P
Sbjct: 339 CPECISRNGYCVYEETGEFMSSNASEVKRIPE--GEKWEDGPCKVCECRGAQVTCYEPSC 396
Query: 137 DECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKG 196
C L++ C T CH C TC+ S C C
Sbjct: 397 PPCPVGTLALEVKGQCCPDCTSVH---------------CHPDCLTCSQSPDHCDLCQDP 441
Query: 197 AYLLAQA-CVSSCPQGTWPSVRSGS-CENCTEACAICSGADLCKKCQMQPGHPLFLHEGR 254
LL CV SC G + ++GS C C C+ C+ C CQ PL + G+
Sbjct: 442 TKLLQNGWCVHSCGLGFY---QAGSLCLACQPQCSTCTSGLECSSCQP----PLLMRHGQ 494
Query: 255 CYSKCPEGSYAEDGICERCSSPCRTCEG-NATNCHSCEGG-HVLHHGVCQENCPERHVAV 312
C C +G Y + C C C C G +C +C HVL G C+ +C +
Sbjct: 495 CVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNR 554
Query: 313 KGVCKHCPEMCQDC-IHEKTCKECTPEFFLHDDMCHQSCPRGFYADSR-HCVPCHKDCLE 370
+G C C + C C C CT + LHD C CP G+YAD+ C CH C
Sbjct: 555 QGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSCAS 614
Query: 371 CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGT--CT 428
CSGP C C L G CL C G Y + C+ CH SCL C CT
Sbjct: 615 CSGPTPSHCTACSPPK-ALRQGHCLPRCGEGFYSDHGV--CKACHSSCLACMGPAPSHCT 671
Query: 429 TCQK---GLIMN-------PRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQ 478
C+K GL + P G C+A + + ++ E C+ CH CF C G +
Sbjct: 672 GCKKPEEGLQVEQLSDVGIPSGECLAQCR---AHFYLESTGICEACHQSCFRCAGKSPHN 728
Query: 479 CQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQC---------- 528
C C + +LL+ C+ CP+GY+ E S C CH +CR C G C
Sbjct: 729 CTDCGPSHVLLDGQCLSQCPDGYFHQEGS--CTECHPTCRQCHGPLESDCISCYPHISLT 786
Query: 529 -----HSCRPGWFQ-------------------------------------LGKECLLQC 546
SCR F LG C+ C
Sbjct: 787 NGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPDC 846
Query: 547 REGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSK---------------- 590
GYYA+ G C++C+ SC+ CQG P C SCD L +
Sbjct: 847 PSGYYAER--GACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNH 904
Query: 591 ------------------------------GEC-HRSCPDHYYVEQSTQTCERCHPTCDQ 619
GEC + SC YY++ ST TC+ C +C
Sbjct: 905 VCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSA 964
Query: 620 CKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNC 679
C G +CL C+ Y L G C CL Y+ + C KC C++C+GP C
Sbjct: 965 CSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQ----DSGLC-KCDSYCLQCQGP--HEC 1017
Query: 680 TLCPANLVLHMDDSHCLHCC 699
T C +L ++ C+ C
Sbjct: 1018 TRCKGPFLLL--EAQCVQEC 1035
Score = 274 bits (700), Expect = 3e-73
Identities = 192/704 (27%), Positives = 263/704 (37%), Gaps = 131/704 (18%)
Query: 107 KCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW 166
+CG G + G+C CE C P G C + + + + W
Sbjct: 260 RCGKGQSRARRHGQC------CEECVSPA---------------GSCSYDGVVRYQDEMW 298
Query: 167 NDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLL------AQACVSSCPQGTWPSVRSGS 220
+ C TC C + L+ C+S +
Sbjct: 299 KGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFM 358
Query: 221 CENCTEACAICSGADL----CKKCQMQPGHPLFLHEGRCYSKCPEGSYA---EDGICERC 273
N +E I G CK C+ + G + +E C CP G+ A + C C
Sbjct: 359 SSNASEVKRIPEGEKWEDGPCKVCECR-GAQVTCYEPSC-PPCPVGTLALEVKGQCCPDC 416
Query: 274 SS-----PCRTCEGNATNCHSCEGG-HVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCI 327
+S C TC + +C C+ +L +G C +C +C C C C
Sbjct: 417 TSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCT 476
Query: 328 HEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSW 387
C C P + C +C GFY D C CH+ C C GP C C +
Sbjct: 477 SGLECSSCQPPLLMRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLH 536
Query: 388 VLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCS-SSGTCTTCQKGLIMNPRGSCMANE 446
VL DG C C G Y + T C C +SC +C SS C TC + +++ G CM+
Sbjct: 537 VLRDGGCESSCGKGFYNRQGT--CSACDQSCDSCGPSSPRCLTCTEKTVLHD-GKCMSE- 592
Query: 447 KCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADED 506
P Y+ + CK CH C C GP C C L C+ C EG+Y+D
Sbjct: 593 --CPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDH- 649
Query: 507 SNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQL-----------GKECLLQCREGYYADNS 555
C CHSSC C G C C+ L ECL QCR +Y + S
Sbjct: 650 -GVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLE-S 707
Query: 556 TGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHP 615
TG CE C++SC C G P +C C LL G+C CPD Y+ ++ +C CHP
Sbjct: 708 TGICEACHQSCFRCAGKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEG--SCTECHP 763
Query: 616 TCDQCKGKGALNCLSCVWSYHLMGGICTSDC----------------------------- 646
TC QC G +C+SC L G C + C
Sbjct: 764 TCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNT 823
Query: 647 -------------LVGEYRVGE------GEKFNCEKCHESCMECKGPGAKNCTLCPANLV 687
L+G++ V + E+ C+KCH SC C+G G +C+ C NLV
Sbjct: 824 GSICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLV 883
Query: 688 L--------------HMDDSHCLHCCNT--SDPPSAQECCDCQD 715
L ++DD+H CNT S C C+D
Sbjct: 884 LSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQASCTSCRD 927
Score = 222 bits (565), Expect = 1e-57
Identities = 150/499 (30%), Positives = 216/499 (43%), Gaps = 57/499 (11%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCGSC------DQNGCYWCEEGF--------FLLGGSC 104
HC C E YS+ CKAC S+C +C GC EEG + G C
Sbjct: 636 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGEC 695
Query: 105 VRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGK 164
+ +C FY + G CE+CH++C C G C+ C LL G C+ +G
Sbjct: 696 LAQCRAHFY-LESTGICEACHQSCFRCAGKSPHNCTDCGPSHVLLDGQCLSQC---PDGY 751
Query: 165 FWNDILRKLQPCHSSCKTCNGS-ATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCEN 223
F + CH +C+ C+G + C SC L C +SC + + ++ G C +
Sbjct: 752 FHQE--GSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNL-VGYCAD 808
Query: 224 CTEACAICSG-----ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCR 278
C C C+ +C +C Q H L L + C CP G YAE G C++C S CR
Sbjct: 809 CHHLCQHCAADLHNTGSICLRC--QNAHYLLLGD-HCVPDCPSGYYAERGACKKCHSSCR 865
Query: 279 TCEGNAT-NCHSCEGGHVLHH-GVCQENC-PERHVAVKGVCKHCPEMCQDCIHEKTCKEC 335
TC+G +C SC+ VL H G C C P ++ VC+ C C C + +C C
Sbjct: 866 TCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQASCTSC 925
Query: 336 TP--EFFLHDDMCHQSCPRGFYAD--SRHCVPCHKDCLECSGPKADDCELCLESSWVLYD 391
+ L + ++SC +Y D + C C C CSGP DC C++ +VL D
Sbjct: 926 RDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCMD-GYVLQD 984
Query: 392 GLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPS 451
G C+E+C + Y +++ C+ C CL C CT C KG + C+ ++C
Sbjct: 985 GACVEQCLSSFY--QDSGLCK-CDSYCLQCQGPHECTRC-KGPFLLLEAQCV--QECGKG 1038
Query: 452 EYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCA 511
+ D C C C C D+C C L + CV +C G+
Sbjct: 1039 YFADHAKHKCTACPQGCLQC--SHRDRCHLCDHGFFLKSGLCVYNCVPGF---------- 1086
Query: 512 HCHSSCRTCEGR-HSRQCH 529
H+S TC G+ H+ H
Sbjct: 1087 SVHTSNETCSGKIHTPSLH 1105
Score = 210 bits (535), Expect = 4e-54
Identities = 190/758 (25%), Positives = 268/758 (35%), Gaps = 204/758 (26%)
Query: 142 CQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLA 201
C E + G C H K E G W PC S +CN CT P
Sbjct: 84 CPECVLRTPGSCHHEKKIHEHGTEWAS-----SPC--SVCSCNHGEVRCTPQPCPPLSCG 136
Query: 202 QACVSSCPQGTWPSVRSGSCENCT-EACAICSGAD----LCKKCQMQPG---------HP 247
++ P+G+ V G + C+ E G D C KC + G P
Sbjct: 137 HQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQP 196
Query: 248 LFLHE--------GRCYSKCPEGSYAEDGIC-----ERCSSPCRT--CEGNATNCHS--- 289
LF ++ G+C +C S + G + + C T C+ CH
Sbjct: 197 LFCNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQAC 256
Query: 290 ----CEGG--HVLHHGVCQENC--PERHVAVKGVCKHCPEM-----CQDCIHE------- 329
C G HG C E C P + GV ++ EM C+ C+ +
Sbjct: 257 LPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQ 316
Query: 330 --------------------KTCKEC-----------TPEFFLHDDMCHQSCPRGFYADS 358
K C EC T EF + + P G +
Sbjct: 317 TGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED 376
Query: 359 RHCVPCH------------------------------KDC---------LECSGPKADDC 379
C C DC L CS D C
Sbjct: 377 GPCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCS-QSPDHC 435
Query: 380 ELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPR 439
+LC + + +L +G C+ C G Y + C C C TC+S C++CQ L+M
Sbjct: 436 DLCQDPTKLLQNGWCVHSCGLGFY--QAGSLCLACQPQCSTCTSGLECSSCQPPLLMR-H 492
Query: 440 GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE----------------------- 476
G C+ C Y +D C CH C C GP E
Sbjct: 493 GQCVPT--CGDGFY--QDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCG 548
Query: 477 ------------------------DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAH 512
+C TC ++L + C+ +CP GYYAD + RC
Sbjct: 549 KGFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADA-TGRCKV 607
Query: 513 CHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGP 572
CH+SC +C G C +C P CL +C EG+Y+D+ G C+ C+ SC C GP
Sbjct: 608 CHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDH--GVCKACHSSCLACMGP 665
Query: 573 RPTDCLSC---------DRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK 623
P+ C C ++ + GEC C H+Y+E ST CE CH +C +C GK
Sbjct: 666 APSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLE-STGICEACHQSCFRCAGK 724
Query: 624 GALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCP 683
NC C S+ L+ G C S C G + ++ +C +CH +C +C GP +C C
Sbjct: 725 SPHNCTDCGPSHVLLDGQCLSQCPDGYFH----QEGSCTECHPTCRQCHGPLESDCISCY 780
Query: 684 ANLVLHMDDSHCLHCCNTSDPPS-AQECCDCQDTTDEC 720
++ L + +C C + C DC C
Sbjct: 781 PHISL--TNGNCRTSCREEQFLNLVGYCADCHHLCQHC 816
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 156 bits (395), Expect = 7e-38
Identities = 90/249 (36%), Positives = 117/249 (46%), Gaps = 20/249 (8%)
Query: 452 EYWDEDAPGCKPCHVKCFH--CMGPAEDQCQTC-PMNSLLLNTT--CVKDCPEGYYADED 506
+Y ED G PC +C C GP D C C L N T CV CP G+Y D
Sbjct: 626 DYGTEDYAG--PCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHY-HAD 682
Query: 507 SNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKE---CLLQCREGYYADNSTGRCERCN 563
RC C +C +C G H QC SC+ G+F L +E C+ C +G Y D C +C+
Sbjct: 683 KKRCRKCAPNCESCFGSHGDQCMSCKYGYF-LNEETNSCVTHCPDGSYQDTKKNLCRKCS 741
Query: 564 RSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK 623
+CK C +C C L S+ C SC D Y + Q C+ CH C C G
Sbjct: 742 ENCKTCTEFH--NCTECRDGLSLQGSR--CSVSCEDGRYF--NGQDCQPCHRFCATCAGA 795
Query: 624 GALNCLSCVWSYHLMGGICTSDCLVGEY--RVGEGEKFNCEKCHESCMECKGPGAKNCTL 681
GA C++C Y + G C C + Y E +C+KC SC+ C GPG KNCT
Sbjct: 796 GADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTS 855
Query: 682 CPANLVLHM 690
CP+ +L +
Sbjct: 856 CPSGYLLDL 864
Score = 140 bits (353), Expect = 5e-33
Identities = 86/300 (28%), Positives = 114/300 (38%), Gaps = 63/300 (21%)
Query: 351 PRGFYADSRHCVPCHKDCLE--CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKET 408
P Y + PC +C E C GP D C CL YY K
Sbjct: 623 PTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLH------------------YYYKLK 664
Query: 409 KECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKC 468
R C SC P ++ D C+ C C
Sbjct: 665 NNTRICVSSC-------------------------------PPGHYHADKKRCRKCAPNC 693
Query: 469 FHCMGPAEDQCQTCPMNSLLLNTT--CVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSR 526
C G DQC +C L T CV CP+G Y D N C C +C+TC H+
Sbjct: 694 ESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHN- 752
Query: 527 QCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
C CR G G C + C +G Y + C+ C+R C C G C++C +F+
Sbjct: 753 -CTECRDGLSLQGSRCSVSCEDGRYFNGQD--CQPCHRFCATCAGAGADGCINCTEGYFM 809
Query: 587 LRSKGECHRSCPDHYYVEQSTQ----TCERCHPTCDQCKGKGALNCLSCVWSYHLMGGIC 642
G C +SC YY + S++ +C++C +C C G G NC SC Y L G+C
Sbjct: 810 --EDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMC 867
Score = 137 bits (345), Expect = 4e-32
Identities = 80/254 (31%), Positives = 117/254 (46%), Gaps = 18/254 (7%)
Query: 218 SGSCE-NCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSY-AEDGICERCSS 275
+G C+ C+E G D C C + + L + C S CP G Y A+ C +C+
Sbjct: 633 AGPCDPECSEVGCDGPGPDHCNDC-LHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAP 691
Query: 276 PCRTCEGN-ATNCHSCEGGHVLHHGV--CQENCPERHV--AVKGVCKHCPEMCQDCIHEK 330
C +C G+ C SC+ G+ L+ C +CP+ K +C+ C E C+ C
Sbjct: 692 NCESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFH 751
Query: 331 TCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLY 390
C EC L C SC G Y + + C PCH+ C C+G AD C C E + +
Sbjct: 752 NCTECRDGLSLQGSRCSVSCEDGRYFNGQDCQPCHRFCATCAGAGADGCINCTE-GYFME 810
Query: 391 DGLCLEECPAGTYYEKET----KECRDCHKSCLTCSSSG--TCTTCQKGLIMNPRGSCMA 444
DG C++ C Y++ + K C+ C SCLTC+ G CT+C G +++ G C
Sbjct: 811 DGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLD-LGMCQM 869
Query: 445 NEKC--SPSEYWDE 456
C + E W E
Sbjct: 870 GAICKDATEESWAE 883
Score = 114 bits (284), Expect = 5e-25
Identities = 90/300 (30%), Positives = 120/300 (40%), Gaps = 40/300 (13%)
Query: 65 PEKTYSEAVECKACDSNCGS--CDQNG---CYWCEEGFFLLGGS---CVRKCGPGFYGDQ 116
P Y CD C CD G C C ++ L + CV C PG Y
Sbjct: 623 PTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHY-HA 681
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEG--LQLLRGMCV-HATKTQEEGKFWNDILRKL 173
+ C C CE+C G D+C SC+ G L CV H +G + +
Sbjct: 682 DKKRCRKCAPNCESCFGSHGDQCMSCKYGYFLNEETNSCVTHC----PDGSYQDTKKNLC 737
Query: 174 QPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC-- 231
+ C +CKTC CT C G L C SC G + C+ C CA C
Sbjct: 738 RKCSENCKTCTEFHN-CTECRDGLSLQGSRCSVSCEDGRY--FNGQDCQPCHRFCATCAG 794
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSY----AEDGI--CERCSSPCRTCEG-NA 284
+GAD C C F+ +GRC C Y +E+G C++C C TC G
Sbjct: 795 AGADGCINCT----EGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGF 850
Query: 285 TNCHSCEGGHVLHHGVCQ-----ENCPERHVAVKGVCKHCPE--MCQ-DCIHEKTCKECT 336
NC SC G++L G+CQ ++ E A G C + +CQ + + CK CT
Sbjct: 851 KNCTSCPSGYLLDLGMCQMGAICKDATEESWAEGGFCMLVKKNNLCQRKVLQQLCCKTCT 910
Score = 95.9 bits (237), Expect = 1e-19
Identities = 63/208 (30%), Positives = 91/208 (43%), Gaps = 37/208 (17%)
Query: 54 NRFDHHCYKTCPEKTYSEAVE--CKACDSNCGSCDQ-NGCYWCEEGFFLLGGSCVRKCGP 110
N + C CP+ +Y + + C+ C NC +C + + C C +G L G C C
Sbjct: 714 NEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCED 773
Query: 111 GFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATK-------TQEEG 163
G Y + + +C+ CHR C TC G G D C +C EG + G CV + + E G
Sbjct: 774 GRYFNGQ--DCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENG 831
Query: 164 KFWNDILRKLQPCHSSCKTCNGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCE 222
+ + C SC TCNG CTSCP G YLL + C G C+
Sbjct: 832 ------YKSCKKCDISCLTCNGPGFKNCTSCPSG-YLLD---LGMCQMG-------AICK 874
Query: 223 NCTEA-------CAICSGADLCKKCQMQ 243
+ TE C + +LC++ +Q
Sbjct: 875 DATEESWAEGGFCMLVKKNNLCQRKVLQ 902
>gi|4505577 paired basic amino acid cleaving system 4 isoform a
preproprotein [Homo sapiens]
Length = 969
Score = 141 bits (355), Expect = 3e-33
Identities = 85/275 (30%), Positives = 119/275 (43%), Gaps = 25/275 (9%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKETKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 813 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Query: 537 QLGKECLLQCREGYYADNSTGR----CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGE 592
+C+ C EG+Y + G C RC+ +C C G +C C F L +
Sbjct: 872 FHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRCKTGFTQLGTSCI 930
Query: 593 CHRSC--PDHYYVE--QSTQTCER------CHPTC 617
+ +C D + E +S + CER C TC
Sbjct: 931 TNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTC 965
Score = 133 bits (334), Expect = 8e-31
Identities = 67/226 (29%), Positives = 100/226 (44%), Gaps = 23/226 (10%)
Query: 513 CHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCK 567
CH C + C+G ++ QC +C G + ++C+ C GY+ D + RC RC++ C+
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 568 GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN 627
C T CLSC R F+ + C CP +Y ++S + C +CHP+C +C +
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE-K 813
Query: 628 CLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLV 687
C C + L G C DC G Y + E C +CH +C C GPG + C C N
Sbjct: 814 CTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREECIHCAKN-- 869
Query: 688 LHMDDSHCLHCCNTSDPPSA-------------QECCDCQDTTDEC 720
H D C+ C P + C C ++ C
Sbjct: 870 FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNC 915
Score = 116 bits (291), Expect = 8e-26
Identities = 66/228 (28%), Positives = 92/228 (40%), Gaps = 20/228 (8%)
Query: 79 DSNCGSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGECESCHRACETCTG 133
D C + + C C F LG CV C G++GD C CH+ CETC+
Sbjct: 701 DKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSS 758
Query: 134 PGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSC 193
+C SC+ G + M T G + ++ + CH SCK C CT C
Sbjct: 759 RAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSCKKCVDEPEKCTVC 817
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCKKCQMQPGHPLFLH 251
+G L +C+ C GT+ C C C C G + C C H
Sbjct: 818 KEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKN----FHFH 873
Query: 252 EGRCYSKCPEGSYAED------GICERCSSPCRTCEGNATNCHSCEGG 293
+ +C C EG Y E+ +C RC C +C G++ NC C+ G
Sbjct: 874 DWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTG 921
Score = 108 bits (269), Expect = 3e-23
Identities = 77/245 (31%), Positives = 103/245 (42%), Gaps = 23/245 (9%)
Query: 254 RCYSKCPEGSYAEDGI--CERCSSPCRTCEGNA-TNCHSCEGGHVLHH--GVCQENCPER 308
+C S CP G + + C RC C TC A T C SC G H C CP
Sbjct: 728 KCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAG 787
Query: 309 HVAVKGV--CKHCPEMCQDCIHE-KTCKECTPEFFLHDDMCHQSCPRGFYADSR--HCVP 363
A + C C C+ C+ E + C C F L C C G Y DS C
Sbjct: 788 FYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGE 847
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK----ETKECRDCHKSCL 419
CH C C GP ++C C + ++ +D C+ C G Y E+ K CR C ++CL
Sbjct: 848 CHHTCGTCVGPGREECIHCAK-NFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCL 906
Query: 420 TCS-SSGTCTTCQKGLIMNPRGSCMANEKCS-PSEYWDEDAPGCKPCHVKCFHCMGPAED 477
+C+ SS C+ C+ G SC+ N CS E + E + C K F +
Sbjct: 907 SCAGSSRNCSRCKTGFTQLGT-SCITNHTCSNADETFCEMVKSNRLCERKLF-----IQF 960
Query: 478 QCQTC 482
C+TC
Sbjct: 961 CCRTC 965
Score = 103 bits (256), Expect = 9e-22
Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCGSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 765 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 824
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQ 160
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 825 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPAC--- 881
Query: 161 EEGKFWNDI----LRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSV 216
EG + ++ + + C +C +C GS+ C+ C G L +C++
Sbjct: 882 GEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTGFTQLGTSCIT---------- 931
Query: 217 RSGSCENCTEA-CAICSGADLCKK 239
+ +C N E C + LC++
Sbjct: 932 -NHTCSNADETFCEMVKSNRLCER 954
Score = 100 bits (250), Expect = 4e-21
Identities = 65/227 (28%), Positives = 97/227 (42%), Gaps = 23/227 (10%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVKGV-CKHCPEMCQDCIH--EKTCKECTPEFFL 341
C C+ G L G C +C P + + + C C C C+ + C C F
Sbjct: 813 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 872
Query: 342 HDDMCHQSCPRGFYADS------RHCVPCHKDCLECSGPKADDCELC 382
HD C +C GFY + + C C ++CL C+G + +C C
Sbjct: 873 HDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRC 918
>gi|20336180 paired basic amino acid cleaving system 4 isoform b
preproprotein [Homo sapiens]
Length = 956
Score = 141 bits (355), Expect = 3e-33
Identities = 85/275 (30%), Positives = 119/275 (43%), Gaps = 25/275 (9%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKETKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 800 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 858
Query: 537 QLGKECLLQCREGYYADNSTGR----CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGE 592
+C+ C EG+Y + G C RC+ +C C G +C C F L +
Sbjct: 859 FHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRCKTGFTQLGTSCI 917
Query: 593 CHRSC--PDHYYVE--QSTQTCER------CHPTC 617
+ +C D + E +S + CER C TC
Sbjct: 918 TNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTC 952
Score = 133 bits (335), Expect = 6e-31
Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 23/235 (9%)
Query: 504 DEDSNRCAHCHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGR 558
+++ + CH C + C+G ++ QC +C G + ++C+ C GY+ D + R
Sbjct: 673 EDEEDYTGVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 559 CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCD 618
C RC++ C+ C T CLSC R F+ + C CP +Y ++S + C +CHP+C
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCK 792
Query: 619 QCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKN 678
+C + C C + L G C DC G Y + E C +CH +C C GPG +
Sbjct: 793 KCVDEPE-KCTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREE 849
Query: 679 CTLCPANLVLHMDDSHCLHCCNTSDPPSA-------------QECCDCQDTTDEC 720
C C N H D C+ C P + C C ++ C
Sbjct: 850 CIHCAKN--FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNC 902
Score = 118 bits (296), Expect = 2e-26
Identities = 68/241 (28%), Positives = 97/241 (40%), Gaps = 20/241 (8%)
Query: 66 EKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGE 120
E+ Y+ + D C + + C C F LG CV C G++GD
Sbjct: 675 EEDYTGVCHPECGDKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
C CH+ CETC+ +C SC+ G + M T G + ++ + CH SC
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSC 791
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCK 238
K C CT C +G L +C+ C GT+ C C C C G + C
Sbjct: 792 KKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECI 851
Query: 239 KCQMQPGHPLFLHEGRCYSKCPEGSYAED------GICERCSSPCRTCEGNATNCHSCEG 292
C H+ +C C EG Y E+ +C RC C +C G++ NC C+
Sbjct: 852 HCAKN----FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKT 907
Query: 293 G 293
G
Sbjct: 908 G 908
Score = 108 bits (269), Expect = 3e-23
Identities = 77/245 (31%), Positives = 103/245 (42%), Gaps = 23/245 (9%)
Query: 254 RCYSKCPEGSYAEDGI--CERCSSPCRTCEGNA-TNCHSCEGGHVLHH--GVCQENCPER 308
+C S CP G + + C RC C TC A T C SC G H C CP
Sbjct: 715 KCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAG 774
Query: 309 HVAVKGV--CKHCPEMCQDCIHE-KTCKECTPEFFLHDDMCHQSCPRGFYADSR--HCVP 363
A + C C C+ C+ E + C C F L C C G Y DS C
Sbjct: 775 FYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGE 834
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK----ETKECRDCHKSCL 419
CH C C GP ++C C + ++ +D C+ C G Y E+ K CR C ++CL
Sbjct: 835 CHHTCGTCVGPGREECIHCAK-NFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCL 893
Query: 420 TCS-SSGTCTTCQKGLIMNPRGSCMANEKCS-PSEYWDEDAPGCKPCHVKCFHCMGPAED 477
+C+ SS C+ C+ G SC+ N CS E + E + C K F +
Sbjct: 894 SCAGSSRNCSRCKTGFTQLGT-SCITNHTCSNADETFCEMVKSNRLCERKLF-----IQF 947
Query: 478 QCQTC 482
C+TC
Sbjct: 948 CCRTC 952
Score = 103 bits (256), Expect = 9e-22
Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCGSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 752 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 811
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQ 160
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 812 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPAC--- 868
Query: 161 EEGKFWNDI----LRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSV 216
EG + ++ + + C +C +C GS+ C+ C G L +C++
Sbjct: 869 GEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTGFTQLGTSCIT---------- 918
Query: 217 RSGSCENCTEA-CAICSGADLCKK 239
+ +C N E C + LC++
Sbjct: 919 -NHTCSNADETFCEMVKSNRLCER 941
Score = 100 bits (250), Expect = 4e-21
Identities = 65/227 (28%), Positives = 97/227 (42%), Gaps = 23/227 (10%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVKGV-CKHCPEMCQDCIH--EKTCKECTPEFFL 341
C C+ G L G C +C P + + + C C C C+ + C C F
Sbjct: 800 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 859
Query: 342 HDDMCHQSCPRGFYADS------RHCVPCHKDCLECSGPKADDCELC 382
HD C +C GFY + + C C ++CL C+G + +C C
Sbjct: 860 HDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRC 905
>gi|20336184 paired basic amino acid cleaving system 4 isoform h
preproprotein [Homo sapiens]
Length = 962
Score = 137 bits (346), Expect = 3e-32
Identities = 74/204 (36%), Positives = 92/204 (45%), Gaps = 12/204 (5%)
Query: 455 DEDAPGCKPCHVKCFH--CMGPAEDQCQTC---PMNSLLLNTTCVKDCPEGYYADEDSNR 509
+ED G CH +C C GP DQC C + S+ + CV CP GY+ D + R
Sbjct: 675 EEDYTGV--CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 510 CAHCHSSCRTCEGRHSRQCHSCRPGWF--QLGKECLLQCREGYYADNSTGRCERCNRSCK 567
C CH C TC R + QC SCR G++ Q C+ C G+YAD S C +C+ SCK
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCK 792
Query: 568 GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN 627
C P C C F L R G C C Y + C CH TC C G G
Sbjct: 793 KCVD-EPEKCTVCKEGFSLAR--GSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREE 849
Query: 628 CLSCVWSYHLMGGICTSDCLVGEY 651
C+ C ++H C C G Y
Sbjct: 850 CIHCAKNFHFHDWKCVPACGEGFY 873
Score = 133 bits (334), Expect = 8e-31
Identities = 63/201 (31%), Positives = 97/201 (48%), Gaps = 10/201 (4%)
Query: 504 DEDSNRCAHCHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGR 558
+++ + CH C + C+G ++ QC +C G + ++C+ C GY+ D + R
Sbjct: 673 EDEEDYTGVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 559 CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCD 618
C RC++ C+ C T CLSC R F+ + C CP +Y ++S + C +CHP+C
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCK 792
Query: 619 QCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKN 678
+C + C C + L G C DC G Y + E C +CH +C C GPG +
Sbjct: 793 KCVDEPE-KCTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREE 849
Query: 679 CTLCPANLVLHMDDSHCLHCC 699
C C N H D C+ C
Sbjct: 850 CIHCAKN--FHFHDWKCVPAC 868
Score = 124 bits (312), Expect = 3e-28
Identities = 65/201 (32%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKETKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 800 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 858
Query: 537 QLGKECLLQCREGYYADNSTG 557
+C+ C EG+Y + G
Sbjct: 859 FHDWKCVPACGEGFYPEEMPG 879
Score = 98.2 bits (243), Expect = 3e-20
Identities = 61/224 (27%), Positives = 86/224 (38%), Gaps = 20/224 (8%)
Query: 66 EKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGE 120
E+ Y+ + D C + + C C F LG CV C G++GD
Sbjct: 675 EEDYTGVCHPECGDKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
C CH+ CETC+ +C SC+ G + M T G + ++ + CH SC
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSC 791
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCK 238
K C CT C +G L +C+ C GT+ C C C C G + C
Sbjct: 792 KKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECI 851
Query: 239 KCQMQPGHPLFLHEGRCYSKCPEGSYAED------GICERCSSP 276
C H+ +C C EG Y E+ +C R P
Sbjct: 852 HCAKN----FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRYGPP 891
Score = 94.0 bits (232), Expect = 5e-19
Identities = 65/227 (28%), Positives = 95/227 (41%), Gaps = 18/227 (7%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVKGV-CKHCPEMCQDCIH--EKTCKECTPEFFL 341
C C+ G L G C +C P + + + C C C C+ + C C F
Sbjct: 800 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 859
Query: 342 HDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWV 388
HD C +C GFY + +P HK C GP + + + S V
Sbjct: 860 HDWKCVPACGEGFYPEEMPGLP-HKVCRR-YGPPGGERQAAVSSKGV 904
Score = 91.3 bits (225), Expect = 3e-18
Identities = 55/175 (31%), Positives = 75/175 (42%), Gaps = 26/175 (14%)
Query: 562 CNRSC--KGCQGPRPTDCLSCDRFFF-LLRSKGECHRSCPDHYYVEQSTQTCERCHPTCD 618
C+ C KGC GP CL+C F +++ +C CP Y+ + + + C RCH C+
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 619 QCKGKGALNCLSCV--WSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGA 676
C + A CLSC + +H C + C G Y E +K NC KCH SC +C
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFY-ADESQK-NCLKCHPSCKKCVDEPE 799
Query: 677 KNCTLCPANLVL-------------HMDDS-----HCLHCCNTSDPPSAQECCDC 713
K CT+C L + D C H C T P +EC C
Sbjct: 800 K-CTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 853
Score = 87.0 bits (214), Expect = 7e-17
Identities = 43/116 (37%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCGSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 752 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 811
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 812 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPA 867
>gi|20336182 paired basic amino acid cleaving system 4 isoform g
preproprotein [Homo sapiens]
Length = 975
Score = 137 bits (344), Expect = 6e-32
Identities = 71/195 (36%), Positives = 88/195 (45%), Gaps = 10/195 (5%)
Query: 464 CHVKCFH--CMGPAEDQCQTC---PMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCR 518
CH +C C GP DQC C + S+ + CV CP GY+ D + RC CH C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 519 TCEGRHSRQCHSCRPGWF--QLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTD 576
TC R + QC SCR G++ Q C+ C G+YAD S C +C+ SCK C P
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVD-EPEK 813
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYH 636
C C F L R G C C Y + C CH TC C G G C+ C ++H
Sbjct: 814 CTVCKEGFSLAR--GSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Query: 637 LMGGICTSDCLVGEY 651
C C G Y
Sbjct: 872 FHDWKCVPACGEGFY 886
Score = 132 bits (333), Expect = 1e-30
Identities = 63/192 (32%), Positives = 93/192 (48%), Gaps = 10/192 (5%)
Query: 513 CHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCK 567
CH C + C+G ++ QC +C G + ++C+ C GY+ D + RC RC++ C+
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 568 GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN 627
C T CLSC R F+ + C CP +Y ++S + C +CHP+C +C +
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE-K 813
Query: 628 CLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLV 687
C C + L G C DC G Y + E C +CH +C C GPG + C C N
Sbjct: 814 CTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREECIHCAKN-- 869
Query: 688 LHMDDSHCLHCC 699
H D C+ C
Sbjct: 870 FHFHDWKCVPAC 881
Score = 124 bits (312), Expect = 3e-28
Identities = 65/201 (32%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKETKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 813 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Query: 537 QLGKECLLQCREGYYADNSTG 557
+C+ C EG+Y + G
Sbjct: 872 FHDWKCVPACGEGFYPEEMPG 892
Score = 96.3 bits (238), Expect = 1e-19
Identities = 59/211 (27%), Positives = 81/211 (38%), Gaps = 20/211 (9%)
Query: 79 DSNCGSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGECESCHRACETCTG 133
D C + + C C F LG CV C G++GD C CH+ CETC+
Sbjct: 701 DKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSS 758
Query: 134 PGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSC 193
+C SC+ G + M T G + ++ + CH SCK C CT C
Sbjct: 759 RAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSCKKCVDEPEKCTVC 817
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCKKCQMQPGHPLFLH 251
+G L +C+ C GT+ C C C C G + C C H
Sbjct: 818 KEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKN----FHFH 873
Query: 252 EGRCYSKCPEGSYAED------GICERCSSP 276
+ +C C EG Y E+ +C R P
Sbjct: 874 DWKCVPACGEGFYPEEMPGLPHKVCRRYGPP 904
Score = 94.0 bits (232), Expect = 5e-19
Identities = 65/227 (28%), Positives = 95/227 (41%), Gaps = 18/227 (7%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVKGV-CKHCPEMCQDCIH--EKTCKECTPEFFL 341
C C+ G L G C +C P + + + C C C C+ + C C F
Sbjct: 813 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 872
Query: 342 HDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWV 388
HD C +C GFY + +P HK C GP + + + S V
Sbjct: 873 HDWKCVPACGEGFYPEEMPGLP-HKVCRR-YGPPGGERQAAVSSKGV 917
Score = 91.7 bits (226), Expect = 3e-18
Identities = 59/194 (30%), Positives = 82/194 (42%), Gaps = 31/194 (15%)
Query: 548 EGYYADNSTG-----RCERCNRSC--KGCQGPRPTDCLSCDRFFF-LLRSKGECHRSCPD 599
E Y A ++ G + C+ C KGC GP CL+C F +++ +C CP
Sbjct: 676 EDYTAQSTPGSANILQTSVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPL 735
Query: 600 HYYVEQSTQTCERCHPTCDQCKGKGALNCLSCV--WSYHLMGGICTSDCLVGEYRVGEGE 657
Y+ + + + C RCH C+ C + A CLSC + +H C + C G Y E +
Sbjct: 736 GYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFY-ADESQ 794
Query: 658 KFNCEKCHESCMECKGPGAKNCTLCPANLVL-------------HMDDS-----HCLHCC 699
K NC KCH SC +C K CT+C L + D C H C
Sbjct: 795 K-NCLKCHPSCKKCVDEPEK-CTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTC 852
Query: 700 NTSDPPSAQECCDC 713
T P +EC C
Sbjct: 853 GTCVGPGREECIHC 866
Score = 87.0 bits (214), Expect = 7e-17
Identities = 43/116 (37%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCGSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 765 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 824
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 825 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPA 880
Score = 47.4 bits (111), Expect = 6e-05
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 8/81 (9%)
Query: 60 CYKTCPEKTY--SEAVECKACDSNCGSCDQNG---CYWCEEGFFLLGGSCVRKCGPGFYG 114
C C TY SE + C C CG+C G C C + F CV CG GFY
Sbjct: 828 CIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPACGEGFYP 887
Query: 115 DQEMGECESCHRACETCTGPG 135
++ G H+ C PG
Sbjct: 888 EEMPG---LPHKVCRRYGPPG 905
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 128 bits (321), Expect = 3e-29
Identities = 169/675 (25%), Positives = 231/675 (34%), Gaps = 154/675 (22%)
Query: 78 CDSNCG-----SCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRA-CE- 129
CD C SCD ++G C G L +C++ C PG+YG C+ CH A C+
Sbjct: 144 CDKPCSCGNNSSCDPKSGVCSCPSG--LQPPNCLQPCTPGYYGPACQFRCQ-CHGAPCDP 200
Query: 130 ---TC------TGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
C TGP D SC +G C Q G F Q SC
Sbjct: 201 QTGACFCPAERTGPSCD--VSCSQGTSGF--FCPSTHSCQNGGVF--------QTPQGSC 248
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK- 239
SCP G + C CP+G NC++ C C LC +
Sbjct: 249 -----------SCPPG--WMGTICSLPCPEGF-------HGPNCSQECR-CHNGGLCDRF 287
Query: 240 ---CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVL 296
C+ PG+ RC +CP G + +D C+ C C +A C G +
Sbjct: 288 TGQCRCAPGYT----GDRCREECPVGRFGQD-----CAETC-DCAPDA-RCFPANGACLC 336
Query: 297 HHGVCQENCPERHV--AVKGVCKHCPEMCQDCIHEKTCK------ECTPEFF-LHDDMCH 347
HG + C +R G+ P C D H +C C P + LH C+
Sbjct: 337 EHGFTGDRCTDRLCPDGFYGLSCQAPCTC-DREHSLSCHPMNGECSCLPGWAGLH---CN 392
Query: 348 QSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKE 407
+SCP+ H C + CL G + + C CP TY
Sbjct: 393 ESCPQ-----DTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNC 447
Query: 408 TKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
+ C C + G C C++G RG+C + C P + C+ H
Sbjct: 448 SARC-SCENAIACSPIDGEC-VCKEGW---QRGNC--SVPCPPGTWGFSCNASCQCAH-- 498
Query: 468 CFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQ 527
Q C C CP+G + + ++RC HS C+ H R
Sbjct: 499 ----EAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD--GCDPVHGR- 551
Query: 528 CHSCRPGWFQLGKECLLQCREGYYADNSTGRC-----------------------ERCNR 564
C C+ GW +G C L C EG + N + C C R
Sbjct: 552 C-QCQAGW--MGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQR 608
Query: 565 SCK-GCQGPRPTDCLSCDRFFFLLRSKG-----------ECHRSCPDHYYVEQSTQTCER 612
SC+ G G R C C F S G +C + CP ++ E QTC+
Sbjct: 609 SCQPGRYGKRCVPC-KCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQ- 666
Query: 613 CH--PTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNC---EKCHES 667
CH TC G SC+ G C C +G + + C EKCH
Sbjct: 667 CHHGGTCHPQDG-------SCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPE 719
Query: 668 CMECKGPGAKNCTLC 682
C P + C
Sbjct: 720 TGACVCPPGHSGAPC 734
Score = 76.3 bits (186), Expect = 1e-13
Identities = 110/434 (25%), Positives = 146/434 (33%), Gaps = 121/434 (27%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCGSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQE 117
HC ++CP+ T+ + + G C +G C G+ G C C P YG
Sbjct: 390 HCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGY--TGPHCASLCPPDTYGVNC 447
Query: 118 MGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCH 177
C SC A P EC C+EG Q RG C G C+
Sbjct: 448 SARC-SCENA--IACSPIDGEC-VCKEGWQ--RGNCSVPCPPGTWG----------FSCN 491
Query: 178 SSCK-----TCNGSATLCTSCP--KGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
+SC+ C+ CT P GA+ C CP+G + E C C
Sbjct: 492 ASCQCAHEAVCSPQTGACTCTPGWHGAH-----CQLPCPKGQFG-------EGCASRCD- 538
Query: 231 CSGADLCK----KCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN 286
C +D C +CQ Q G RC+ CPEG + + CS+ C TC+ T
Sbjct: 539 CDHSDGCDPVHGRCQCQAG----WMGARCHLSCPEGLWGVN-----CSNTC-TCKNGGT- 587
Query: 287 CHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMC 346
C+ E C P F C
Sbjct: 588 ---------------------------------------CLPENGNCVCAPGF--RGPSC 606
Query: 347 HQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK 406
+SC G Y + CVPC P C CL + W D C + CP G + E
Sbjct: 607 QRSCQPGRY--GKRCVPCKCANHSFCHPSNGTC-YCL-AGWTGPD--CSQPCPPGHWGEN 660
Query: 407 ETKECR-----DCHK---SCLTCSSSGTCTTCQKGLIMNPRGS-------CMANEKCSPS 451
+ C+ CH SC+ C T C +G + G+ C EKC P
Sbjct: 661 CAQTCQCHHGGTCHPQDGSCI-CPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHP- 718
Query: 452 EYWDEDAPGCKPCH 465
+ A C P H
Sbjct: 719 ---ETGACVCPPGH 729
Score = 53.9 bits (128), Expect = 6e-07
Identities = 79/340 (23%), Positives = 103/340 (30%), Gaps = 117/340 (34%)
Query: 461 CKP-CHVKCFHCMGPAEDQCQ--------------------------------------- 480
C P C +C H A +QCQ
Sbjct: 101 CVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKS 160
Query: 481 -TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHS-------------------SCRT- 519
C S L C++ C GYY RC CH SC
Sbjct: 161 GVCSCPSGLQPPNCLQPCTPGYYGPACQFRC-QCHGAPCDPQTGACFCPAERTGPSCDVS 219
Query: 520 ---------CEGRHSRQ----------CHSCRPGWFQLGKECLLQCREGYYADNSTGRCE 560
C HS Q SC PGW +G C L C EG++ N
Sbjct: 220 CSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGW--MGTICSLPCPEGFHGPN------ 271
Query: 561 RCNRSCKGCQGPRPTDCLSCDRFFFLLR-----SKGECHRSCPDHYYVEQSTQTCERCHP 615
C++ C+ G CDRF R + C CP + + +TC+ C P
Sbjct: 272 -CSQECRCHNGG------LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD-CAP 323
Query: 616 TCDQCKGKGALNCLSCVWSYHLMGGICTSD-CLVGEYRVGEGEKFNCEKCHE-SCMECKG 673
GA C+ + G CT C G Y + C++ H SC G
Sbjct: 324 DARCFPANGA-----CLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNG 378
Query: 674 PGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDC 713
C+ P LH ++S C + P QE C C
Sbjct: 379 ----ECSCLPGWAGLHCNES----CPQDTHGPGCQEHCLC 410
Score = 31.2 bits (69), Expect = 4.3
Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQ-- 116
C + CP + E + G+C Q+G C G+ G C+ C G +G
Sbjct: 648 CSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGW--TGHHCLEGCPLGTFGANCS 705
Query: 117 ---EMGECESCHRACETCTGPGHDECSSCQEGLQ 147
+ G E CH C P + C+ G+Q
Sbjct: 706 QPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 116 bits (291), Expect = 8e-26
Identities = 171/690 (24%), Positives = 235/690 (34%), Gaps = 165/690 (23%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQ-NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C +TCP T+ + N G+CD G C G + G +C C G+YG
Sbjct: 551 CNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPG--VSGTNCEDGCPKGYYGKHCR 608
Query: 119 GECE-----SCHRACETCTGPGHDECSSCQEGLQLLRGMCVHAT-KTQEEGKFWNDILRK 172
+C CHR C C GL G H T G ++ +
Sbjct: 609 KKCNCANRGRCHRLYGACL---------CDPGLY---GRFCHLTCPPWAFGPGCSEECQC 656
Query: 173 LQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT----EAC 228
+QP SC +GS SC G + C + C G + G + CT AC
Sbjct: 657 VQPHTQSCDKRDGSC----SCKAG--FRGERCQAECELGYF---GPGCWQACTCPVGVAC 707
Query: 229 AICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPC----RTCEGNA 284
SG + K+C P C +CP G++ + CSS C C G
Sbjct: 708 DSVSG-ECGKRC------PAGFQGEDCGQECPVGTFGVN-----CSSSCSCGGAPCHGVT 755
Query: 285 TNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKE------CTPE 338
C C G C+ +CPE + C E+C C H C C P
Sbjct: 756 GQCR-CPPGRTGED--CEADCPEGRWGL-----GCQEICPACQHAARCDPETGACLCLPG 807
Query: 339 FFLHDDMCHQSCPRGFY----------ADSRHCVPCHKDCLECSGPKADDCELCLES--- 385
F C CP G+Y A+ HC P C G C+ ++
Sbjct: 808 FV--GSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW 865
Query: 386 ---------------SWVLYDGLCL-----------EECPAGTYYEKETKECRDCHKSCL 419
S GLCL ++CP G + + C+ C
Sbjct: 866 GPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAA 924
Query: 420 TCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQC 479
SG C TC G RG+ E P+ ++ D C C G A D
Sbjct: 925 CDHVSGAC-TCPAGW----RGTFC--EHACPAGFFGLD------CRSACNCTAGAACDAV 971
Query: 480 Q-TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQL 538
+C + C + CP Y S CA C + +C+ H QCH C PGW +
Sbjct: 972 NGSCLCPAGRRGPRCAETCPAHTYGHNCSQACA-CFNGA-SCDPVHG-QCH-CAPGW--M 1025
Query: 539 GKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCP 598
G CL C G Y DN C SC CQ D +S G C +CP
Sbjct: 1026 GPSCLQACPAGLYGDN-------CRHSCL-CQNGGTCDPVS-----------GHC--ACP 1064
Query: 599 DHYYVEQSTQTCER-CHPTCDQCKGKGALNCLS----------CVWSYHLMGGICTSDCL 647
+ + + CE+ C P + + + CL+ C+ G C S CL
Sbjct: 1065 EGW----AGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 1120
Query: 648 VGEYRVGEGEKFNC---EKCHESCMECKGP 674
G + ++ +C CH C+ P
Sbjct: 1121 RGWFGEACAQRCSCPPGAACHHVTGACRCP 1150
Score = 102 bits (255), Expect = 1e-21
Identities = 150/619 (24%), Positives = 202/619 (32%), Gaps = 170/619 (27%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQ-NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C +TCP TY N SCD +G C G+ +G SC++ C G YGD
Sbjct: 986 CAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGW--MGPSCLQACPAGLYGDNCR 1043
Query: 119 GECESCHRACETCTGPGHDECSSCQEGLQL--------LRGMCVHATKTQEEGKFWNDIL 170
C C GH C GL +R C H+ G
Sbjct: 1044 HSC-LCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGG------- 1095
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
C+ C CP G C S C +G + E C + C+
Sbjct: 1096 -----------LCDPHTGRCL-CPAG--WTGDKCQSPCLRGWFG-------EACAQRCSC 1134
Query: 231 CSGA---DLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNC 287
GA + C+ PG F G C CP GS+ ED C+ C+ C G C
Sbjct: 1135 PPGAACHHVTGACRCPPG---FTGSG-CEQACPPGSFGED-----CAQMCQ-CPGENPAC 1184
Query: 288 H------SCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECT----- 336
H SC G+ H CQ+ CP C ++C C++ +C T
Sbjct: 1185 HPATGTCSCAAGY--HGPSCQQRCPPGRYG-----PGCEQLC-GCLNGGSCDAATGACRC 1236
Query: 337 PEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLE 396
P FL D C+ +CP+G + + C C G D G CL
Sbjct: 1237 PTGFLGTD-CNLTCPQGRFGPN-----CTHVCGCGQGAACDPVT-----------GTCL- 1278
Query: 397 ECPAGTYYEKETKECRD------CHKSCLTCSSSGTCT----TCQKGLIMNPRGSCMANE 446
CP G + + C C +C +C + G C +C GL R +A
Sbjct: 1279 -CPPGRAGVRCERGCPQNRFGVGCEHTC-SCRNGGLCHASNGSCSCGLGWTGRHCELA-- 1334
Query: 447 KCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADED 506
C P Y CH++C +C NS T C G+Y
Sbjct: 1335 -CPPGRYG-------AACHLEC------------SCHNNSTCEPATGTCRCGPGFYG--- 1371
Query: 507 SNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRC------- 559
+ CE H C PG+ G + L C+ G D +GRC
Sbjct: 1372 -----------QACE-------HPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFH 1413
Query: 560 -ERCNRSCK------------GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQS 606
C R C+ C G P D ++ RS C+ C +
Sbjct: 1414 GHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSC 1473
Query: 607 TQTCE-----RCHPTCDQC 620
T C+ C P QC
Sbjct: 1474 TLHCDCGGGADCDPVSGQC 1492
Score = 87.4 bits (215), Expect = 5e-17
Identities = 160/700 (22%), Positives = 227/700 (32%), Gaps = 168/700 (24%)
Query: 102 GSCVRKCGPGFYGDQEMGECESCH---------RACETCTGPGHDECSS----CQEGLQL 148
GSC+ +C + + CE CH +ACE DEC++ C G
Sbjct: 253 GSCMHRCQVV----RGLARCE-CHVGYQLAADGKACEDV-----DECAAGLAQCAHGCLN 302
Query: 149 LRGM--CV-HATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACV 205
+G CV HA E G R +SC+ NG C G + +
Sbjct: 303 TQGSFKCVCHAG--YELGADGRQCYRIEMEIVNSCEANNGG------CSHGCSHTSAGPL 354
Query: 206 SSCPQGTWPSVRSGSCENCTEACAICSGADLCKK-CQMQPGHPLFLHEGRCYSK---CPE 261
+CP+G +C + + C+ + C++ C PG +E CY+ +
Sbjct: 355 CTCPRGYELDTDQRTCIDVDD----CADSPCCQQVCTNNPGG----YECGCYAGYRLSAD 406
Query: 262 GSYAEDGICERCSSPCRTCEGNATNCH-----SCEGGHVLHHGVCQENCPERHVAVKGVC 316
G ED + C+S CE + TN SCE G+ LH + C + +
Sbjct: 407 GCGCED--VDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED--RRGCSPLEEPMVDLD 462
Query: 317 KHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKA 376
P + H ++ P+ F DD+ A
Sbjct: 463 GELP-FVRPLPHIAVLQDELPQLFQDDDV-----------------------------GA 492
Query: 377 DDCELCLESSWVLYDG-LCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLI 435
D+ E L L + +CL++ DC +C C + GTC G
Sbjct: 493 DEEEAELRGEHTLTEKFVCLDDSFG-----------HDCSLTCDDCRNGGTCLLGLDGCD 541
Query: 436 MNPRG--SCMANEKCSPSEYWDEDAPGCKPCHVKCFHCM--GPAEDQCQTCPMNSLLLNT 491
P G + NE C P + K C C C G + C + T
Sbjct: 542 C-PEGWTGLICNETCPPDTFG-------KNCSFSC-SCQNGGTCDSVTGACRCPPGVSGT 592
Query: 492 TCVKDCPEGYYADE--------DSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECL 543
C CP+GYY + RC + +C G + R CH P W G C
Sbjct: 593 NCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPW-AFGPGCS 651
Query: 544 LQC------------REGYYADNSTGRCERCNRSCK-GCQGPRPTDCLSCDRFFFLLRSK 590
+C R+G + + R ERC C+ G GP +C
Sbjct: 652 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS 711
Query: 591 GECHRSCPDHYYVEQSTQTCE------RCHPTCDQCKGKGALNCL-SCVWSYHLMGGICT 643
GEC + CP + E Q C C +C C G C G C
Sbjct: 712 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSC-SCGGAPCHGVTGQCRCPPGRTGEDCE 770
Query: 644 SDCLVGEYRVGEGEKFNCEKCHESCMECK-----GPGAKNCTLCPANLVLHMDDSHCLHC 698
+DC G + +G C E C C+ P C P + S C
Sbjct: 771 ADCPEGRWGLG---------CQEICPACQHAARCDPETGACLCLPGFV-----GSRCQDV 816
Query: 699 CNTS-DPPSAQECCDCQDTTDECILRTSKVRPATEHFKTA 737
C PS Q C C + PAT H A
Sbjct: 817 CPAGWYGPSCQTRCSCAN--------DGHCHPATGHCSCA 848
Score = 45.8 bits (107), Expect = 2e-04
Identities = 53/190 (27%), Positives = 67/190 (35%), Gaps = 48/190 (25%)
Query: 59 HCYKTCPEKTYSEA--VECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQ 116
HC CP Y A +EC +C +N G C GF+ G +C C PGF+G
Sbjct: 1330 HCELACPPGRYGAACHLEC-SCHNNSTCEPATGTCRCGPGFY--GQACEHPCPPGFHGAG 1386
Query: 117 EMGECESCHRA-CETCTG----PGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILR 171
G C H A C+ +G P C+ G E G F
Sbjct: 1387 CQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGC--------------EPGSFG----- 1427
Query: 172 KLQPCHSSCKTCNGSAT------LCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT 225
+ CH C C+G A LC CP G C C +G + +CT
Sbjct: 1428 --EGCHQRC-DCDGGAPCDPVTGLCL-CPPGR--SGATCNLDCRRGQFG-------PSCT 1474
Query: 226 EACAICSGAD 235
C GAD
Sbjct: 1475 LHCDCGGGAD 1484
Score = 43.9 bits (102), Expect = 6e-04
Identities = 72/323 (22%), Positives = 101/323 (31%), Gaps = 61/323 (18%)
Query: 426 TCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC----MGPA----ED 477
T C +G + P + +CS S + C P + HC GP D
Sbjct: 106 TVLRCCRGWMQQPDEEGCLSAECSASLCFHGGR--CVPGSAQPCHCPPGFQGPRCQYDVD 163
Query: 478 QCQT----CPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQC----- 528
+C+T C + + + +C G+ DS C +S C G C
Sbjct: 164 ECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINS-CALGNGGCQHHCVQLTI 222
Query: 529 --HSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
H C QCR G+ C R C G SC +
Sbjct: 223 TRHRC-------------QCRPGFQLQEDGRHCVR-RSPCANRNG-------SCMHRCQV 261
Query: 587 LRSKGECHRSCPDHYYVEQSTQTCE---RCHPTCDQC-----KGKGALNCLSCVWSYHLM 638
+R C C Y + + CE C QC +G+ C+ C Y L
Sbjct: 262 VRGLARCE--CHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCV-CHAGYEL- 317
Query: 639 GGICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPGAKNCTLCPANLVLHMDDSHCLH 697
G C YR+ +CE + C C A CP L D C+
Sbjct: 318 -GADGRQC----YRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCID 372
Query: 698 CCNTSDPPSAQECCDCQDTTDEC 720
+ +D P Q+ C EC
Sbjct: 373 VDDCADSPCCQQVCTNNPGGYEC 395
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 109 bits (273), Expect = 9e-24
Identities = 171/704 (24%), Positives = 225/704 (31%), Gaps = 146/704 (20%)
Query: 43 PVQKQIHLKCGNRFDHHCYKTCPEKTYSEAVECKACDSNCGSCDQ-NGCYWCEEGFFLLG 101
P+ H G R C C + TY + N +CD G C G+ G
Sbjct: 162 PITGACHCAAGFR-GWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGY--TG 218
Query: 102 GSCVRKCGPGFYGDQEMGECESCHRA--CETCTGPGHDECSSCQEGLQLLRGMCVHATKT 159
C C PG +G Q C C C TG ECS C G M +
Sbjct: 219 AFCEDLCPPGKHGPQCEQRCP-CQNGGVCHHVTG----ECS-CPSGW-----MGTVCGQP 267
Query: 160 QEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSG 219
EG+F + ++ Q CH+ TC+ + C P + C CP GT+ + +
Sbjct: 268 CPEGRFGKNCSQECQ-CHNG-GTCDAATGQCHCSPG---YTGERCQDECPVGTYGVLCAE 322
Query: 220 SCENCTEA--CAICSGADLCKKCQMQPGHPLFLHEGRCYSK-CPEGSYAEDGICERCSSP 276
+C+ C C SGA LC+ F E RC ++ CPEG Y GI +C
Sbjct: 323 TCQ-CVNGGKCYHVSGACLCEAG--------FAGE-RCEARLCPEGLY---GI--KCDKR 367
Query: 277 CRTCEGNATNCHSCEGGHVLHHG----VCQENCPERHVAVKGVCKHCPEMCQ-----DCI 327
C N +CH G G C E C + C ++C DC
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYG-----EACQQICSCQNGADCD 422
Query: 328 HEKTCKECTPEFFLHDDMCHQSCPRGFYA----------DSRHCVPCHKDCLECSGPKAD 377
C P F D C CP G Y + C P C +G
Sbjct: 423 SVTGKCTCAPGFKGID--CSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 378 DCEL-CLESSWVL----------------YDGLCLEECPAGTYYEKETKECRD------C 414
DC + C +W DG C C G EK C+D C
Sbjct: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCT--CAPGWRGEKCELPCQDGTYGLNC 538
Query: 415 HKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCK-PCHVKCFHCMG 473
+ C CS + C P S + + W P C PC+ K
Sbjct: 539 AERC-DCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRW---GPNCSLPCYCKNGASCS 594
Query: 474 PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRP 533
P + C+ P TTC + C G+Y S C C S C H C P
Sbjct: 595 PDDGICECAPG---FRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPC--HHITGLCDCLP 649
Query: 534 GWFQLGKECLLQCREGYYADNSTGRCE-----RCNRSCKGCQ------------------ 570
G+ G C C G + N G C CN + CQ
Sbjct: 650 GF--TGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAH 707
Query: 571 -GPRPTDCLSCDRFFFLLRSKGECH-----------RSCPDHYYVEQSTQTCE-RCHPTC 617
GP +C F GEC + CP +Y + C+ + C
Sbjct: 708 WGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC 767
Query: 618 DQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNC 661
D G+ C MG C C G Y G + +C
Sbjct: 768 DHISGQ-------CTCRTGFMGRHCEQKCPSGTYGYGCRQICDC 804
Score = 71.2 bits (173), Expect = 4e-12
Identities = 75/290 (25%), Positives = 102/290 (35%), Gaps = 54/290 (18%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCGSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQE 117
HC C E + N SC +G C GF G +C R C PGFYG +
Sbjct: 567 HCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF--RGTTCQRICSPGFYGHR- 623
Query: 118 MGECESCHRACETC---TGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQ 174
C + C C +GP H C +C + GK
Sbjct: 624 ------CSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGK---------- 667
Query: 175 PCHSSCKTCNGSAT---LCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC 231
C C TC + T + SC + C CP W +C NC A C
Sbjct: 668 NCAGIC-TCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC-NCHNG-AFC 724
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCH--- 288
S D +C+ PG C +CP G Y +D C+ C+ C+ A H
Sbjct: 725 SAYD--GECKCTPGWTGLY----CTQRCPLGFYGKD-----CALICQ-CQNGADCDHISG 772
Query: 289 --SCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECT 336
+C G + H C++ CP C ++C DC++ TC T
Sbjct: 773 QCTCRTGFMGRH--CEQKCPSGTYGY-----GCRQIC-DCLNNSTCDHIT 814
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 107 bits (268), Expect = 4e-23
Identities = 153/544 (28%), Positives = 200/544 (36%), Gaps = 145/544 (26%)
Query: 58 HHCYKTCPEKTYSEAVECKACDSNCGSCDQ--NGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
HHC ++CP Y + + N C GC C GF +G C C G YG
Sbjct: 388 HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCT-CAPGF--MGEVCAVSCAAGTYGP 444
Query: 116 QEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQP 175
C SC+ TC+ P C+ C+EG Q L T G + +
Sbjct: 445 NCSSIC-SCNNG-GTCS-PVDGSCT-CKEGWQGL-----DCTLPCPSGTWGLN------- 488
Query: 176 CHSSCKTCNGSAT--LCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
C+ SC NG+A + SC L C CP GT+ NC+E C CS
Sbjct: 489 CNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGL-------NCSEHCD-CSH 540
Query: 234 ADLCKKCQMQPGHPLFLHEG---RCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSC 290
AD C GH L RC S CP G + + CS C SC
Sbjct: 541 AD---GCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPN-----CSVSC-----------SC 581
Query: 291 EGGHVLHHGVCQENCPERHVAVKGVCKHCP----EMCQDCIHEKTCKECTPEFFLHDDMC 346
E G G C PE G C+ P +CQ + C P F+ H C
Sbjct: 582 ENG-----GSCS---PE-----DGSCECAPGFRGPLCQ--------RICPPGFYGHG--C 618
Query: 347 HQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK 406
Q CP CV + C SG CE CL LC + C AG Y+ +
Sbjct: 619 AQPCPL--------CVHSSRPCHHISGI----CE-CLPG---FSGALCNQVC-AGGYFGQ 661
Query: 407 ETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCH- 465
DC + C +C+++GTC+ GSC +C P + + C P
Sbjct: 662 ------DCAQLC-SCANNGTCSPID--------GSC----QCFPGWIGKDCSQACPPGFW 702
Query: 466 -VKCFHCMG-------PAED-QCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHS- 515
CFH AED C P + L C + CP ++ +D R C +
Sbjct: 703 GPACFHACSCHNGASCSAEDGACHCTPGWTGLF---CTQRCPAAFFG-KDCGRVCQCQNG 758
Query: 516 ----------SCRT-CEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNR 564
+CRT G+H Q C PG F G + L +C D+ TG C C+
Sbjct: 759 ASCDHISGKCTCRTGFTGQHCEQ--RCAPGTFGYGCQQLCECMNNSTCDHVTGTC-YCSP 815
Query: 565 SCKG 568
KG
Sbjct: 816 GFKG 819
Score = 98.2 bits (243), Expect = 3e-20
Identities = 173/699 (24%), Positives = 230/699 (32%), Gaps = 149/699 (21%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
HC C + C+ G+C C GF G C C PG +G
Sbjct: 141 HCSNRC------QCQNGALCNPITGACV------CAAGF--RGWRCEELCAPGTHGKGCQ 186
Query: 119 GECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHS 178
C+ H A +C P EC C G + C G LR PC +
Sbjct: 187 LPCQCRHGA--SCD-PRAGECL-CAPGYTGV--YCEELCPPGSHGAHCE--LRC--PCQN 236
Query: 179 SCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGAD--- 235
TC+ C +CP G C CP GT+ +NC++ C G
Sbjct: 237 G-GTCHHITGEC-ACPPG--WTGAVCAQPCPPGTFG-------QNCSQDCPCHHGGQCDH 285
Query: 236 LCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGN----ATNCHSCE 291
+ +C G+ RC +CP GS+ +CS C G T CE
Sbjct: 286 VTGQCHCTAGYM----GDRCQEECPFGSFGF-----QCSQHCDCHNGGQCSPTTGACECE 336
Query: 292 GGHVLHHGVCQEN-CPERHVAVKGVCKHCPEMCQDCI--HEKT-CKECTPEFFLHDDMCH 347
G+ CQE CPE + G CP + I H T C P + H C+
Sbjct: 337 PGYKGPR--CQERLCPEG-LHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHH--CN 391
Query: 348 QSCPRGFYADSRHCVPCHKDCLECSGPKADDCEL----CLESSWVLYDGLCLEECPAGTY 403
+SCP G+Y D C L C+ DC C + + + +C C AGTY
Sbjct: 392 ESCPVGYYGDG-----CQ---LPCTCQNGADCHSITGGCTCAPGFMGE-VCAVSCAAGTY 442
Query: 404 YEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANE-----KCS---PSEYWD 455
+C C +C++ GTC+ GSC E C+ PS W
Sbjct: 443 GP-------NCSSIC-SCNNGGTCSPVD--------GSCTCKEGWQGLDCTLPCPSGTWG 486
Query: 456 EDAPGCKPCHVKCFHCMG----PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCA 511
+ C+ C G P + C P L TC CP+G + S C
Sbjct: 487 LN------CNESCTCANGAACSPIDGSCSCTPG---WLGDTCELPCPDGTFGLNCSEHCD 537
Query: 512 HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCK--GC 569
H+ C+ C C GW G C C G + N + C SC+ G
Sbjct: 538 CSHAD--GCDPVTGHCC--CLAGW--TGIRCDSTCPPGRWGPNCSVSC-----SCENGGS 586
Query: 570 QGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKG-KGALNC 628
P C F L C R CP +Y Q C C + C G C
Sbjct: 587 CSPEDGSCECAPGFRGPL-----CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICEC 641
Query: 629 LSCVWSYHLMGGICTSDCLVGEY------RVGEGEKFNCEKCHESCMECKGPGAKNCT-L 681
L G +C C G + C SC G K+C+
Sbjct: 642 LP-----GFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQA 696
Query: 682 CPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CP C H C+ + S C +D C
Sbjct: 697 CPPGFW----GPACFHACSCHNGAS----CSAEDGACHC 727
Score = 65.5 bits (158), Expect = 2e-10
Identities = 89/384 (23%), Positives = 122/384 (31%), Gaps = 92/384 (23%)
Query: 393 LCLEECPAGTYYEKETKECR------DCHKSCLTCSSSGTCTT---CQKGLIMNP-RGSC 442
LC EEC G +T C DC C + C+ CQ G + NP G+C
Sbjct: 102 LCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGAC 161
Query: 443 M---------ANEKCSPSEYWDEDAPGCK-PCHVKCFHCMGPAEDQCQTCPMNSLLLNTT 492
+ E C+P + GC+ PC + P +C P +
Sbjct: 162 VCAAGFRGWRCEELCAPGTH----GKGCQLPCQCRHGASCDPRAGECLCAPGYT---GVY 214
Query: 493 CVKDCPEGYYAD--------EDSNRCAHCHSSCRTCEGRHSRQC-HSCRPGWFQLGKECL 543
C + CP G + ++ C H C G C C PG F G+ C
Sbjct: 215 CEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTF--GQNCS 272
Query: 544 --LQCREGYYADNSTGRC--------ERCNRSCK-GCQGPRPTDCLSCDRFFFLLRSKGE 592
C G D+ TG+C +RC C G G + + C + G
Sbjct: 273 QDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA 332
Query: 593 C------------HRSCPDHYYVEQSTQTCE-------RCHPTCDQCKGKGALNCLSCVW 633
C R CP+ + T C CHP C + W
Sbjct: 333 CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPG-------W 385
Query: 634 SYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHE--SCMECKGPGAKNCTLCPANLVLHMD 691
S H C C VG Y G+G + C C C G CT P M
Sbjct: 386 SGH----HCNESCPVGYY--GDGCQLPC-TCQNGADCHSITG----GCTCAPG----FMG 430
Query: 692 DSHCLHCCNTSDPPSAQECCDCQD 715
+ + C + P+ C C +
Sbjct: 431 EVCAVSCAAGTYGPNCSSICSCNN 454
Score = 50.1 bits (118), Expect = 9e-06
Identities = 75/317 (23%), Positives = 97/317 (30%), Gaps = 67/317 (21%)
Query: 447 KCSPSEYWDEDAPGCKP-CHVKCFH--CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYA 503
+C P Y E C P C +C H C+ P TC C C ++
Sbjct: 87 QCCPGYY--ESGDFCIPLCTEECVHGRCVSP-----DTCHCEPGWGGPDCSSGCDSDHWG 139
Query: 504 DEDSNRC-----AHCH---SSCRTCEGRHSRQCHS-CRPGWFQLGKECLLQCREGYYADN 554
SNRC A C+ +C G +C C PG G + QCR G D
Sbjct: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP 199
Query: 555 STGRC--------ERCNRSC-KGCQGPRPTDCLSCDRFFFLLRSKGE-----------CH 594
G C C C G G C GE C
Sbjct: 200 RAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCA 259
Query: 595 RSCPDHYYVEQSTQTCERCH--PTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYR 652
+ CP + + +Q C CH CD G+ C + MG C +C G +
Sbjct: 260 QPCPPGTFGQNCSQDCP-CHHGGQCDHVTGQ-------CHCTAGYMGDRCQEECPFGSFG 311
Query: 653 VGEGEKFNCE---KCHESCMEC------KGPGAKNCTLCPANLVLHMDDSHCLHCCNTSD 703
+ +C +C + C KGP + LCP LH C
Sbjct: 312 FQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQE-RLCPEG--LHGPG------CTLPC 362
Query: 704 PPSAQECCDCQDTTDEC 720
P A C T C
Sbjct: 363 PCDADNTISCHPVTGAC 379
Score = 32.3 bits (72), Expect = 1.9
Identities = 39/184 (21%), Positives = 62/184 (33%), Gaps = 49/184 (26%)
Query: 526 RQCHSCRPGWFQLGKECLLQCRE----GYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
R+ C PG+++ G C+ C E G T CE G GP
Sbjct: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCE------PGWGGP--------- 127
Query: 582 RFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCL--SCVWSYHLMG 639
+C C ++ + C QC+ N + +CV + G
Sbjct: 128 ----------DCSSGCDSDHWGPHCSNRC--------QCQNGALCNPITGACVCAAGFRG 169
Query: 640 GICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDD-----SH 694
C C G + G+G + C+ H + + P A C P ++ ++ SH
Sbjct: 170 WRCEELCAPGTH--GKGCQLPCQCRHGASCD---PRAGECLCAPGYTGVYCEELCPPGSH 224
Query: 695 CLHC 698
HC
Sbjct: 225 GAHC 228
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 90.1 bits (222), Expect = 8e-18
Identities = 112/432 (25%), Positives = 150/432 (34%), Gaps = 98/432 (22%)
Query: 320 PEMCQD---CIHEKTCKECTPEFFLHDDMCHQSCPRGFYA-DSRHCVPCHKDCLECSGPK 375
P+ CQ C+ C+ C P FF C CP ++ D R PCH +C P
Sbjct: 60 PDACQKDEVCVKPGLCR-CKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHG-QCE-PA 114
Query: 376 ADDCELCLESSWVLYDGLCLEECPAGTY--YEKETKECR--------DCHKSCLTCSSSG 425
C+ C W C C G + + T C C + C +++
Sbjct: 115 TGACQ-CQADRW---GARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 426 TCTTCQKGLIMNP-----RGSCMANEKCSPSEYWDEDAPGCKP------CHVKCFHCMG- 473
C + P R S N SP E D C+P C +C G
Sbjct: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQ-DSGRCACRPGWWGPECQQQCECVRGR 229
Query: 474 --PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH---------SSCRTCE- 521
A +C TCP C CP G + + ++ C C SC +CE
Sbjct: 230 CSAASGEC-TCPPG--FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 522 GRHSRQCHS-CRPGWFQLGKECLLQC---REGYYADNSTGRCERCNRSCKGCQGPRPTDC 577
G + QC C PG F G+ C QC R G + TG C+RC+ G GPR
Sbjct: 287 GWNGTQCQQPCLPGTF--GESCEQQCPHCRHGEACEPDTGHCQRCD---PGWLGPR---- 337
Query: 578 LSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERC-HPTCDQCKGKGALNCLSCVWSYH 636
C CP + E TC C +CD G CV S
Sbjct: 338 ---------------CEDPCPTGTFGEDCGSTCPTCVQGSCDTVTG-------DCVCSAG 375
Query: 637 LMGGICTSDCLVGEYRVGEGEKFNCE----KCHESCMECK-GPGAKNCTLCPANLV---- 687
G C + C G + G CE CH C+ G G+++ L +LV
Sbjct: 376 YWGPSCNASCPAGFH--GNNCSVPCECPEGLCHPVSGSCQPGSGSRDTALIAGSLVPLLL 433
Query: 688 LHMDDSHCLHCC 699
L + + C CC
Sbjct: 434 LFLGLACCACCC 445
Score = 77.4 bits (189), Expect = 5e-14
Identities = 95/434 (21%), Positives = 142/434 (32%), Gaps = 88/434 (20%)
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---------CQMQP 244
PKG ++ CV+S P ++ IC G D C+K C+ +P
Sbjct: 24 PKGQHV----CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
Query: 245 GHPLFLHEGRCYSKCPEGSYAED----------GICERCSSPCRTCEGN--ATNCH-SCE 291
G C S+CP + D G CE + C+ C+ + C C
Sbjct: 80 G----FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ-CQADRWGARCEFPCA 134
Query: 292 GGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCP 351
G HG C H C CQ C++ T + C
Sbjct: 135 CGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191
Query: 352 RGFYADSRHCVPCHKDCLECS------GPKADDCELCLESSWVLYDGLCL---------- 395
+ + H PC +D C+ GP+ C+ G C
Sbjct: 192 ---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
Query: 396 -EECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
CPAG++ + C C + +G+C +C+ G + C P +
Sbjct: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW-----NGTQCQQPCLPGTFG 303
Query: 455 DEDAPGCKPCHVKCFHC-----MGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNR 509
+ C +C HC P CQ C L C CP G + ++ +
Sbjct: 304 ES-------CEQQCPHCRHGEACEPDTGHCQRCDPG--WLGPRCEDPCPTGTFGEDCGST 354
Query: 510 CAHC-HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST-------GRCER 561
C C SC T G C C G++ G C C G++ +N + G C
Sbjct: 355 CPTCVQGSCDTVTG----DC-VCSAGYW--GPSCNASCPAGFHGNNCSVPCECPEGLCHP 407
Query: 562 CNRSCKGCQGPRPT 575
+ SC+ G R T
Sbjct: 408 VSGSCQPGSGSRDT 421
Score = 73.6 bits (179), Expect = 7e-13
Identities = 99/446 (22%), Positives = 141/446 (31%), Gaps = 96/446 (21%)
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEGLQLLR-GMC--------VHATKTQEEGKFWN 167
E+ C + + CT P + +CQ+ ++ G+C H + ++ G++W
Sbjct: 38 ELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCPGQYWG 96
Query: 168 DILRKLQPC--HSSCKTCNGSATL------------CTSCPKGAYLLAQACVSSCPQGTW 213
R+ PC H C+ G+ C P G A V C G W
Sbjct: 97 PDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG-VCHCEPGWW 155
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERC 273
S C+ C A A C A G C C G + RC
Sbjct: 156 SSTCRRPCQ-CNTAAARCEQA-----------------TGACV--CKPGWWG-----RRC 190
Query: 274 SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCK 333
S C C G+ C G G C ++ V+G C C
Sbjct: 191 SFRC-NCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC---------- 237
Query: 334 ECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECS-----GPKADDCELCLESSWV 388
C P F C CP G H V C C C P CE C E W
Sbjct: 238 TCPPGF--RGARCELPCPAG-----SHGVQCAHSCGRCKHNEPCSPDTGSCESC-EPGW- 288
Query: 389 LYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 448
C + C GT+ E ++C C +G C C G + PR + C
Sbjct: 289 -NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGW-LGPR----CEDPC 342
Query: 449 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSN 508
+ ++ C C G + C ++ +C CP G++ +
Sbjct: 343 PTGTFGEDCGSTCPTC------VQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---- 392
Query: 509 RCAHCHSSCRTCEGRHSRQCHSCRPG 534
+C C EG SC+PG
Sbjct: 393 ---NCSVPCECPEGLCHPVSGSCQPG 415
Score = 55.1 bits (131), Expect = 3e-07
Identities = 74/287 (25%), Positives = 99/287 (34%), Gaps = 57/287 (19%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNC----GSCDQNGCYWCEEGFFLL---GGSCVRK---- 107
HC T +C + C G+C +W F G C +
Sbjct: 149 HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRC 208
Query: 108 -CGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW 166
C PG++G + +CE C +G EC +C G + R C G
Sbjct: 209 ACRPGWWGPECQQQCECVRGRCSAASG----EC-TCPPGFRGAR--CELPCPAGSHG--- 258
Query: 167 NDILRKLQPCHS--SCK---TCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSC 221
+Q HS CK C+ C SC G C C GT+ C
Sbjct: 259 ------VQCAHSCGRCKHNEPCSPDTGSCESCEPG--WNGTQCQQPCLPGTFGESCEQQC 310
Query: 222 ENCT--EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRT 279
+C EAC +G C++C P +L RC CP G++ ED C S C T
Sbjct: 311 PHCRHGEACEPDTGH--CQRCD-----PGWLGP-RCEDPCPTGTFGED-----CGSTCPT 357
Query: 280 CEGNATNCHSCEGGHVLHHGV----CQENCPER-HVAVKGVCKHCPE 321
C +C + G V G C +CP H V CPE
Sbjct: 358 CVQG--SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE 402
Score = 55.1 bits (131), Expect = 3e-07
Identities = 55/187 (29%), Positives = 69/187 (36%), Gaps = 35/187 (18%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQN--------GCYWCEEGFFLLGGSCVRKCGPG 111
C CP ++ C +CG C N C CE G+ G C + C PG
Sbjct: 248 CELPCPAGSHGVQ-----CAHSCGRCKHNEPCSPDTGSCESCEPGWN--GTQCQQPCLPG 300
Query: 112 FYGDQEMGECESCHR--ACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDI 169
+G+ +C C ACE TG C C G L C T G F D
Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTG----HCQRCDPGW--LGPRCEDPCPT---GTFGED- 350
Query: 170 LRKLQPCHSSCKTC-NGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEA 227
C S+C TC GS T+ C A +C +SCP G + S CE
Sbjct: 351 ------CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404
Query: 228 CAICSGA 234
C SG+
Sbjct: 405 CHPVSGS 411
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 20/92 (21%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQNGCYW------CEEGFFLLGGSCVRKCGPGFY 113
C CP T+ E C S C +C Q C C G++ G SC C GF+
Sbjct: 338 CEDPCPTGTFGED-----CGSTCPTCVQGSCDTVTGDCVCSAGYW--GPSCNASCPAGFH 390
Query: 114 GDQEMGECESCHRACETCTGPGHDECSSCQEG 145
G+ +C CE G H SCQ G
Sbjct: 391 GN-------NCSVPCECPEGLCHPVSGSCQPG 415
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 90.1 bits (222), Expect = 8e-18
Identities = 112/432 (25%), Positives = 150/432 (34%), Gaps = 98/432 (22%)
Query: 320 PEMCQD---CIHEKTCKECTPEFFLHDDMCHQSCPRGFYA-DSRHCVPCHKDCLECSGPK 375
P+ CQ C+ C+ C P FF C CP ++ D R PCH +C P
Sbjct: 60 PDACQKDEVCVKPGLCR-CKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHG-QCE-PA 114
Query: 376 ADDCELCLESSWVLYDGLCLEECPAGTY--YEKETKECR--------DCHKSCLTCSSSG 425
C+ C W C C G + + T C C + C +++
Sbjct: 115 TGACQ-CQADRW---GARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 426 TCTTCQKGLIMNP-----RGSCMANEKCSPSEYWDEDAPGCKP------CHVKCFHCMG- 473
C + P R S N SP E D C+P C +C G
Sbjct: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQ-DSGRCACRPGWWGPECQQQCECVRGR 229
Query: 474 --PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH---------SSCRTCE- 521
A +C TCP C CP G + + ++ C C SC +CE
Sbjct: 230 CSAASGEC-TCPPG--FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 522 GRHSRQCHS-CRPGWFQLGKECLLQC---REGYYADNSTGRCERCNRSCKGCQGPRPTDC 577
G + QC C PG F G+ C QC R G + TG C+RC+ G GPR
Sbjct: 287 GWNGTQCQQPCLPGTF--GESCEQQCPHCRHGEACEPDTGHCQRCD---PGWLGPR---- 337
Query: 578 LSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERC-HPTCDQCKGKGALNCLSCVWSYH 636
C CP + E TC C +CD G CV S
Sbjct: 338 ---------------CEDPCPTGTFGEDCGSTCPTCVQGSCDTVTG-------DCVCSAG 375
Query: 637 LMGGICTSDCLVGEYRVGEGEKFNCE----KCHESCMECK-GPGAKNCTLCPANLV---- 687
G C + C G + G CE CH C+ G G+++ L +LV
Sbjct: 376 YWGPSCNASCPAGFH--GNNCSVPCECPEGLCHPVSGSCQPGSGSRDTALIAGSLVPLLL 433
Query: 688 LHMDDSHCLHCC 699
L + + C CC
Sbjct: 434 LFLGLACCACCC 445
Score = 77.4 bits (189), Expect = 5e-14
Identities = 95/434 (21%), Positives = 142/434 (32%), Gaps = 88/434 (20%)
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---------CQMQP 244
PKG ++ CV+S P ++ IC G D C+K C+ +P
Sbjct: 24 PKGQHV----CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
Query: 245 GHPLFLHEGRCYSKCPEGSYAED----------GICERCSSPCRTCEGN--ATNCH-SCE 291
G C S+CP + D G CE + C+ C+ + C C
Sbjct: 80 G----FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ-CQADRWGARCEFPCA 134
Query: 292 GGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCP 351
G HG C H C CQ C++ T + C
Sbjct: 135 CGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191
Query: 352 RGFYADSRHCVPCHKDCLECS------GPKADDCELCLESSWVLYDGLCL---------- 395
+ + H PC +D C+ GP+ C+ G C
Sbjct: 192 ---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
Query: 396 -EECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
CPAG++ + C C + +G+C +C+ G + C P +
Sbjct: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW-----NGTQCQQPCLPGTFG 303
Query: 455 DEDAPGCKPCHVKCFHC-----MGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNR 509
+ C +C HC P CQ C L C CP G + ++ +
Sbjct: 304 ES-------CEQQCPHCRHGEACEPDTGHCQRCDPG--WLGPRCEDPCPTGTFGEDCGST 354
Query: 510 CAHC-HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST-------GRCER 561
C C SC T G C C G++ G C C G++ +N + G C
Sbjct: 355 CPTCVQGSCDTVTG----DC-VCSAGYW--GPSCNASCPAGFHGNNCSVPCECPEGLCHP 407
Query: 562 CNRSCKGCQGPRPT 575
+ SC+ G R T
Sbjct: 408 VSGSCQPGSGSRDT 421
Score = 73.6 bits (179), Expect = 7e-13
Identities = 99/446 (22%), Positives = 141/446 (31%), Gaps = 96/446 (21%)
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEGLQLLR-GMC--------VHATKTQEEGKFWN 167
E+ C + + CT P + +CQ+ ++ G+C H + ++ G++W
Sbjct: 38 ELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCPGQYWG 96
Query: 168 DILRKLQPC--HSSCKTCNGSATL------------CTSCPKGAYLLAQACVSSCPQGTW 213
R+ PC H C+ G+ C P G A V C G W
Sbjct: 97 PDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG-VCHCEPGWW 155
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERC 273
S C+ C A A C A G C C G + RC
Sbjct: 156 SSTCRRPCQ-CNTAAARCEQA-----------------TGACV--CKPGWWG-----RRC 190
Query: 274 SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCK 333
S C C G+ C G G C ++ V+G C C
Sbjct: 191 SFRC-NCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC---------- 237
Query: 334 ECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECS-----GPKADDCELCLESSWV 388
C P F C CP G H V C C C P CE C E W
Sbjct: 238 TCPPGF--RGARCELPCPAG-----SHGVQCAHSCGRCKHNEPCSPDTGSCESC-EPGW- 288
Query: 389 LYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 448
C + C GT+ E ++C C +G C C G + PR + C
Sbjct: 289 -NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGW-LGPR----CEDPC 342
Query: 449 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSN 508
+ ++ C C G + C ++ +C CP G++ +
Sbjct: 343 PTGTFGEDCGSTCPTC------VQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---- 392
Query: 509 RCAHCHSSCRTCEGRHSRQCHSCRPG 534
+C C EG SC+PG
Sbjct: 393 ---NCSVPCECPEGLCHPVSGSCQPG 415
Score = 55.1 bits (131), Expect = 3e-07
Identities = 74/287 (25%), Positives = 99/287 (34%), Gaps = 57/287 (19%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNC----GSCDQNGCYWCEEGFFLL---GGSCVRK---- 107
HC T +C + C G+C +W F G C +
Sbjct: 149 HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRC 208
Query: 108 -CGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW 166
C PG++G + +CE C +G EC +C G + R C G
Sbjct: 209 ACRPGWWGPECQQQCECVRGRCSAASG----EC-TCPPGFRGAR--CELPCPAGSHG--- 258
Query: 167 NDILRKLQPCHS--SCK---TCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSC 221
+Q HS CK C+ C SC G C C GT+ C
Sbjct: 259 ------VQCAHSCGRCKHNEPCSPDTGSCESCEPG--WNGTQCQQPCLPGTFGESCEQQC 310
Query: 222 ENCT--EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRT 279
+C EAC +G C++C P +L RC CP G++ ED C S C T
Sbjct: 311 PHCRHGEACEPDTGH--CQRCD-----PGWLGP-RCEDPCPTGTFGED-----CGSTCPT 357
Query: 280 CEGNATNCHSCEGGHVLHHGV----CQENCPER-HVAVKGVCKHCPE 321
C +C + G V G C +CP H V CPE
Sbjct: 358 CVQG--SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE 402
Score = 55.1 bits (131), Expect = 3e-07
Identities = 55/187 (29%), Positives = 69/187 (36%), Gaps = 35/187 (18%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQN--------GCYWCEEGFFLLGGSCVRKCGPG 111
C CP ++ C +CG C N C CE G+ G C + C PG
Sbjct: 248 CELPCPAGSHGVQ-----CAHSCGRCKHNEPCSPDTGSCESCEPGWN--GTQCQQPCLPG 300
Query: 112 FYGDQEMGECESCHR--ACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDI 169
+G+ +C C ACE TG C C G L C T G F D
Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTG----HCQRCDPGW--LGPRCEDPCPT---GTFGED- 350
Query: 170 LRKLQPCHSSCKTC-NGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEA 227
C S+C TC GS T+ C A +C +SCP G + S CE
Sbjct: 351 ------CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404
Query: 228 CAICSGA 234
C SG+
Sbjct: 405 CHPVSGS 411
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 20/92 (21%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQNGCYW------CEEGFFLLGGSCVRKCGPGFY 113
C CP T+ E C S C +C Q C C G++ G SC C GF+
Sbjct: 338 CEDPCPTGTFGED-----CGSTCPTCVQGSCDTVTGDCVCSAGYW--GPSCNASCPAGFH 390
Query: 114 GDQEMGECESCHRACETCTGPGHDECSSCQEG 145
G+ +C CE G H SCQ G
Sbjct: 391 GN-------NCSVPCECPEGLCHPVSGSCQPG 415
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 76.6 bits (187), Expect = 9e-14
Identities = 123/513 (23%), Positives = 164/513 (31%), Gaps = 134/513 (26%)
Query: 277 CRTCEG-NATNCHSCEGGH-----VLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEK 330
C +G T+C SC G+ +L G+CQ H A V +C C H
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV----HGVCIACAHNT 764
Query: 331 T---CKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELC----L 383
T C++C P F+ RG D C PC S + C L +
Sbjct: 765 TGVHCEQCLPGFYGEPS-------RGTPGD---CQPCACPLTIASNNFSPTCHLNDGDEV 814
Query: 384 ESSWVL--YDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGS 441
W Y G E C G YY T +SC+ C SG
Sbjct: 815 VCDWCAPGYSGAWCERCADG-YYGNPTVP----GESCVPCDCSGNV-------------- 855
Query: 442 CMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAED-QCQTCPMNSLLLNTTCVKDCPEG 500
PSE A C +C C+G + C+ C +G
Sbjct: 856 -------DPSE-----AGHCDSVTGECLKCLGNTDGAHCERCA---------------DG 888
Query: 501 YYADEDSNRCAHCHSSCRTCE----GRHSRQCH------SCRPGWFQLGKECLLQCREGY 550
+Y D A +CR CE G HS CH C+P G++C QC GY
Sbjct: 889 FYGD------AVTAKNCRACECHVKGSHSAVCHLETGLCDCKPN--VTGQQCD-QCLHGY 939
Query: 551 YADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQT- 609
Y +S C CN S G TD C + + C R Y + + T
Sbjct: 940 YGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKR--CDRCAHGFYAYQDGSCTP 997
Query: 610 --CERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKC--- 664
C TCD G+ CV H G C +C G + G + C+ C
Sbjct: 998 CDCPHTQNTCDPETGE-------CVCPPHTQGVKC-EECEDGHW--GYDAEVGCQACNCS 1047
Query: 665 -----HESC------MECKGP-GAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQEC-- 710
H C +CK G + C C + D C+ C S C
Sbjct: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG---YRDFPDCVPCDCDLRGTSGDACNL 1104
Query: 711 ----CDCQDTTDECILRTSKVRPATEHFKTALF 739
C C + T C + + P + F
Sbjct: 1105 EQGLCGCVEETGACPCKENVFGPQCNECREGTF 1137
Score = 55.8 bits (133), Expect = 2e-07
Identities = 110/495 (22%), Positives = 154/495 (31%), Gaps = 132/495 (26%)
Query: 128 CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSA 187
CE G C SC G + G+ + I + + CH CN
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGI------------LFGGICQPCE-CHGHAAECNVHG 755
Query: 188 TLCTSCPKGAYLLAQACVSSCPQGTW--PSVRS-GSCENCTEACAICSGADLCKKCQMQP 244
+C +C A+ C G + PS + G C+ C I S + C +
Sbjct: 756 -VCIAC---AHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASN-NFSPTCHLND 810
Query: 245 GHPLFL------HEGRCYSKCPEGSY---------------------AEDGICERCSSPC 277
G + + G +C +G Y +E G C+ + C
Sbjct: 811 GDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGEC 870
Query: 278 RTCEGNA--TNCHSCEGGHVLHHGVCQENCPERHVAVKG----VCKHCPEMCQDCIHEKT 331
C GN +C C G V +NC VKG VC +C DC T
Sbjct: 871 LKCLGNTDGAHCERCADGFY-GDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVT 928
Query: 332 CKECTPEFFLHDDMCHQSCPRGFYA-DSRH-CVPCH--------------KDCLECSGPK 375
++C C G+Y DS H C PC+ C G
Sbjct: 929 GQQC------------DQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVA 976
Query: 376 ADDCELCLESSWVLYDGLCLE-ECP-AGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKG 433
C+ C + DG C +CP + ET EC C + C C+ G
Sbjct: 977 GKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGEC-----VCPPHTQGVKCEECEDG 1031
Query: 434 LIMNPRGSCMANEKCSPSEYWDEDAP-GCKPC--------HVKCF----HCMGPAEDQCQ 480
+W DA GC+ C H +C HC ++ +
Sbjct: 1032 -------------------HWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGR 1072
Query: 481 TCPMNSLLLNT--TCVK-DCPEGYYADEDSNR------CAHCHSSCRTCEGRHSRQCHSC 531
C SL CV DC + + N C +C E QC+ C
Sbjct: 1073 ACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNEC 1132
Query: 532 RPGWFQLGKECLLQC 546
R G F L + L C
Sbjct: 1133 REGTFALRADNPLGC 1147
Score = 55.1 bits (131), Expect = 3e-07
Identities = 101/480 (21%), Positives = 148/480 (30%), Gaps = 111/480 (23%)
Query: 78 CDSNCGSCDQNG-CYWCEEGFFLLGGSCVRKCGPGFYGDQEM---GECESCHRACE-TCT 132
C + C+ +G C C G C +C PGFYG+ G+C+ C AC T
Sbjct: 744 CHGHAAECNVHGVCIACAHN--TTGVHC-EQCLPGFYGEPSRGTPGDCQPC--ACPLTIA 798
Query: 133 GPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTS 192
+G +++ C S C
Sbjct: 799 SNNFSPTCHLNDGDEVVCDWCAPGY----------------------------SGAWCER 830
Query: 193 CPKGAY----LLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPL 248
C G Y + ++CV G +G C++ T C C G
Sbjct: 831 CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT------------- 877
Query: 249 FLHEGRCYSKCPEGSYAEDGICERC-SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPE 307
+G +C +G Y + + C + C ++ CH G V + C +
Sbjct: 878 ---DGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ 934
Query: 308 RHVAVKGV-----CKHC-----PEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYA- 356
G+ C+ C + C E C C P + C + C GFYA
Sbjct: 935 CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQC-HCVPG--VAGKRCDR-CAHGFYAY 990
Query: 357 DSRHCVPCHKDCLECSG---PKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRD 413
C PC DC P+ +C +C + G+ EEC G + C+
Sbjct: 991 QDGSCTPC--DCPHTQNTCDPETGEC-VCPPHT----QGVKCEECEDGHWGYDAEVGCQA 1043
Query: 414 CHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEK-----CSPSEYWDEDAPGCKPCHVKC 468
C+ S L S+ C G C K C D P C PC
Sbjct: 1044 CNCS-LVGSTHHRCDVV--------TGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDL 1094
Query: 469 FHCMGPA----------EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSN--RCAHCHSS 516
G A ++ CP + C +C EG +A N C+ C S
Sbjct: 1095 RGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC-NECREGTFALRADNPLGCSPCFCS 1153
Score = 50.4 bits (119), Expect = 7e-06
Identities = 73/303 (24%), Positives = 105/303 (34%), Gaps = 58/303 (19%)
Query: 50 LKC-GNRFDHHCYKTCPEKTYSEAV---ECKACDSNCGSCDQNGCY----WCEEGFFLLG 101
LKC GN HC + C + Y +AV C+AC+ + C+ C+ + G
Sbjct: 871 LKCLGNTDGAHCER-CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTG 929
Query: 102 GSCVRKCGPGFYGDQEMGECESCH-----RACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
C +C G+YG C C+ + CT G C G + R C H
Sbjct: 930 QQC-DQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR--CAHG 986
Query: 157 TKTQEEGKFWNDILRKLQPCH--SSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWP 214
++G PC + TC+ C CP + C C G W
Sbjct: 987 FYAYQDG--------SCTPCDCPHTQNTCDPETGECV-CP--PHTQGVKC-EECEDGHWG 1034
Query: 215 SVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE--GRCYSKCPEGSYAEDGICER 272
C+ C C++ +C + GH + GR +C G Y + C
Sbjct: 1035 YDAEVGCQACN--CSLVGSTH--HRCDVVTGHCQCKSKFGGRACDQCSLG-YRDFPDCVP 1089
Query: 273 CSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTC 332
C R G+A N L G+C C E A CP C++ + C
Sbjct: 1090 CDCDLRGTSGDACN---------LEQGLC--GCVEETGA-------CP--CKENVFGPQC 1129
Query: 333 KEC 335
EC
Sbjct: 1130 NEC 1132
Score = 40.0 bits (92), Expect = 0.009
Identities = 64/264 (24%), Positives = 90/264 (34%), Gaps = 52/264 (19%)
Query: 392 GLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNP--RGSCMANEKCS 449
G+C+ A + ET + C TC S C C G P G+ + C
Sbjct: 268 GMCICYGHASSCPWDETTKKLQCQCEHNTCGES--CNRCCPGYHQQPWRPGTVSSGNTCE 325
Query: 450 PSE--------YWDEDAPGCKPCHVKCFHCMGPAEDQ--CQTCPMNSLLLNTTCVKDCPE 499
Y+DE K K + G C C N++ +N + C +
Sbjct: 326 ACNCHNKAKDCYYDESVAKQK----KSLNTAGQFRGGGVCINCLQNTMGINC---ETCID 378
Query: 500 GYYADE-----DSNRCAHCH-------SSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCR 547
GYY + C C+ SS + HS + +PG +C C+
Sbjct: 379 GYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPG------QC--PCK 430
Query: 548 EGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQST 607
EGY + +C+RC K PT C+SC S C C VE
Sbjct: 431 EGYTGE----KCDRCQLGYKDY----PT-CVSCGCNPVGSASDEPCTGPCVCKENVEG-- 479
Query: 608 QTCERCHPTCDQCKGKGALNCLSC 631
+ C+RC P K K C C
Sbjct: 480 KACDRCKPGFYNLKEKNPRGCSEC 503
Score = 39.7 bits (91), Expect = 0.012
Identities = 39/163 (23%), Positives = 59/163 (36%), Gaps = 22/163 (13%)
Query: 176 CHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTE-ACAICSGA 234
C++ TC+ + C +C G C C G + V +GS +C AC A
Sbjct: 1405 CNNHSDTCDPNTGKCLNC--GDNTAGDHC-DVCTSGYYGKV-TGSASDCALCACPHSPPA 1460
Query: 235 DLCKKCQMQPGHP------LFLHEGRCYSKCPEGSYAED----GICERCSSPCRTCEGNA 284
C ++ H L +EG+ +C Y G C++C C
Sbjct: 1461 SFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCD--CNPHGSVH 1518
Query: 285 TNCHSCEGGHVLHHGV----CQENCPERHVAVKGVCKHCPEMC 323
+C G V G C E C RH+ ++ C C + C
Sbjct: 1519 GDCDRTSGQCVCRLGASGLRCDE-CEPRHILMETDCVSCDDEC 1560
Score = 37.4 bits (85), Expect = 0.059
Identities = 63/251 (25%), Positives = 79/251 (31%), Gaps = 75/251 (29%)
Query: 398 CPAGTYYEKETKECRDC----HKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEY 453
CP GT C+DC H+ L S PR CS + +
Sbjct: 1364 CPPGTV----GFSCQDCAPGYHRGKLPAGSD-----------RGPRPLVAPCVPCSCNNH 1408
Query: 454 WDEDAPGCKPCHVKCFHCM-GPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAH 512
D C P KC +C A D C C T DC CA
Sbjct: 1409 SDT----CDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCA----------LCAC 1454
Query: 513 CHSS----CRTC--EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSC 566
HS TC EG H +C +C G+ EG + CERC+ S
Sbjct: 1455 PHSPPASFSPTCVLEGDHDFRCDACLLGY------------EGKH-------CERCSSSY 1495
Query: 567 KGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPT---CDQCKGK 623
G C CD G H C S Q R + CD+C+ +
Sbjct: 1496 YGNPQTPGGSCQKCD-----CNPHGSVHGDCD-----RTSGQCVCRLGASGLRCDECEPR 1545
Query: 624 GAL---NCLSC 631
L +C+SC
Sbjct: 1546 HILMETDCVSC 1556
Score = 35.4 bits (80), Expect = 0.23
Identities = 63/283 (22%), Positives = 99/283 (34%), Gaps = 73/283 (25%)
Query: 292 GGHVLHHGVCQENCP--ERHVAVKGVCKH--CPEMCQDCI---HEK-----------TCK 333
GG + +G +CP E ++ C+H C E C C H++ TC+
Sbjct: 267 GGMCICYGHAS-SCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCE 325
Query: 334 ECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADD--CELCLESSWVLYD 391
C CH +Y +S V K L +G C CL+++
Sbjct: 326 ACN---------CHNKAKDCYYDES---VAKQKKSLNTAGQFRGGGVCINCLQNTM---- 369
Query: 392 GLCLEECPAGTYYEK-----ETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANE 446
G+ E C G Y E + CR C+ C G+ ++ C+ ++
Sbjct: 370 GINCETCIDGYYRPHKVSPYEDEPCRPCN-----CDPVGSLSSV-----------CIKDD 413
Query: 447 KCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDC-PEGYYADE 505
S+ + PG PC G ++C C + T C P G +DE
Sbjct: 414 L--HSDLHNGKQPGQCPCKE------GYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDE 465
Query: 506 DSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCRE 548
C C E + C C+PG++ L ++ C E
Sbjct: 466 P------CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSE 502
>gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Homo
sapiens]
Length = 353
Score = 75.9 bits (185), Expect = 2e-13
Identities = 62/233 (26%), Positives = 81/233 (34%), Gaps = 51/233 (21%)
Query: 414 CHKSCLTCSSSGT----CTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCF 469
C K+ C S GT C CQ G + C N CS D C+ CH
Sbjct: 120 CVKTLKVCCSPGTYGPDCLACQGG----SQRPCSGNGHCSGDGSRQGDG-SCR-CH---- 169
Query: 470 HCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYA---DEDSNRCAHCHSSCRTCEGRHSR 526
MG C DC +GY++ +E + C C SC+TC G +R
Sbjct: 170 --MGYQGPLCT---------------DCMDGYFSSLRNETHSICTACDESCKTCSGLTNR 212
Query: 527 QCHSCRPGWFQLGKECL---------LQCREGYYADNSTG--RCERCNRSCKGCQGPRPT 575
C C GW C+ C + N+ G CE C+ SC GC G P
Sbjct: 213 DCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPG 272
Query: 576 DCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNC 628
+C C + H C D + +TC R + C G C
Sbjct: 273 NCKEC------ISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVC 319
Score = 62.0 bits (149), Expect = 2e-09
Identities = 61/217 (28%), Positives = 81/217 (37%), Gaps = 42/217 (19%)
Query: 493 CVKD----CPEGYYADEDSNRCAHCHSSCRT-------CEGRHSRQCH-SCRPGWFQLGK 540
CVK C G Y + C C + C G SRQ SCR G
Sbjct: 120 CVKTLKVCCSPGTYGPD----CLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGP 175
Query: 541 ECLLQCREGYYAD--NSTGR-CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSK----GEC 593
C C +GY++ N T C C+ SCK C G DC C+ + L EC
Sbjct: 176 LCT-DCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDEC 234
Query: 594 HRSCPDHYYVE-----QSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGIC--TSDC 646
P + + TCE C +C C G+G NC C+ Y G C +C
Sbjct: 235 AAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDEC 294
Query: 647 LVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCP 683
+ E C + +E+C PG+ C +CP
Sbjct: 295 SLAEK--------TCVRKNENCYNT--PGSYVC-VCP 320
Score = 60.1 bits (144), Expect = 9e-09
Identities = 65/277 (23%), Positives = 92/277 (33%), Gaps = 92/277 (33%)
Query: 56 FDHHCYKT----CPEKTYSEAVECKACD-------------SNCGSCDQNGCYWCEEGFF 98
F+ C KT C TY +C AC S GS +G C G+
Sbjct: 116 FEWFCVKTLKVCCSPGTYGP--DCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGY- 172
Query: 99 LLGGSCVRKCGPGFYG---DQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVH 155
G C G++ ++ C +C +C+TC+G + +C C+ G L G CV
Sbjct: 173 --QGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVD 230
Query: 156 ATKTQEEGKFWNDILRKLQPCHSS--CKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTW 213
+ E PC ++ CK NGS T
Sbjct: 231 VDECAAEP----------PPCSAAQFCKNANGSYT------------------------- 255
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGIC--- 270
CE C +C C+G G C +C G E G C
Sbjct: 256 -------CEECDSSCVGCTGEG----------------PGNC-KECISGYAREHGQCADV 291
Query: 271 ERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPE 307
+ CS +TC NC++ G +V VC + E
Sbjct: 292 DECSLAEKTCVRKNENCYNTPGSYVC---VCPDGFEE 325
Score = 55.8 bits (133), Expect = 2e-07
Identities = 65/268 (24%), Positives = 94/268 (35%), Gaps = 85/268 (31%)
Query: 259 CPEGSYAEDGICERCSSPC-RTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCK 317
C G+Y D C C R C GN H G G C+ C H+ +G
Sbjct: 128 CSPGTYGPD--CLACQGGSQRPCSGNG---HCSGDGSRQGDGSCR--C---HMGYQG--- 174
Query: 318 HCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH-----CVPCHKDCLECS 372
+C DC+ G+++ R+ C C + C CS
Sbjct: 175 ---PLCTDCMD------------------------GYFSSLRNETHSICTACDESCKTCS 207
Query: 373 GPKADDCELCLESSWVLYDGLCLE---------ECPAGTYYEKE--TKECRDCHKSCLTC 421
G DC C E WVL +G C++ C A + + + C +C SC+ C
Sbjct: 208 GLTNRDCGEC-EVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGC 266
Query: 422 SSS--GTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQC 479
+ G C C G G C ++CS +E K C K + C
Sbjct: 267 TGEGPGNCKECISG-YAREHGQCADVDECSLAE---------KTCVRK--------NENC 308
Query: 480 QTCPMNSLLLNTTCVKDCPEGYYADEDS 507
P + + CV CP+G+ ED+
Sbjct: 309 YNTPGSYV-----CV--CPDGFEETEDA 329
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/191 (22%), Positives = 64/191 (33%), Gaps = 48/191 (25%)
Query: 251 HEGRCYSKCPEGSYAE-----DGICERCSSPCRTCEG-NATNCHSCEGGHVLHHGVCQEN 304
++G + C +G ++ IC C C+TC G +C CE G VL G C +
Sbjct: 172 YQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVD- 230
Query: 305 CPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPC 364
C C + CK G Y C C
Sbjct: 231 -----------VDECAAEPPPCSAAQFCKNA----------------NGSYT----CEEC 259
Query: 365 HKDCLECSGPKADDCELCLESSWVLYDGLC--LEECPAGTYYEKETKECRDCHKSCLTCS 422
C+ C+G +C+ C+ S + G C ++EC K C +++C
Sbjct: 260 DSSCVGCTGEGPGNCKECI-SGYAREHGQCADVDECSLA------EKTCVRKNENCYNTP 312
Query: 423 SSGTCTTCQKG 433
S C C G
Sbjct: 313 GSYVC-VCPDG 322
Score = 45.1 bits (105), Expect = 3e-04
Identities = 55/223 (24%), Positives = 74/223 (33%), Gaps = 55/223 (24%)
Query: 513 CHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSC--KGCQ 570
C SS C Q W QL E Y D C + + C G
Sbjct: 83 CESSDFECNQMLEAQEEHLEAWWLQLKSE---------YPDLFEWFCVKTLKVCCSPGTY 133
Query: 571 GPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCL- 629
GP DCL+C +G R C + + C G G+
Sbjct: 134 GP---DCLAC---------QGGSQRPCSGNGH-----------------CSGDGSRQGDG 164
Query: 630 SCVWSYHLMGGICTSDCLVGEYRVGEGEKFN-CEKCHESCMECKGPGAKNCTLCPANLVL 688
SC G +CT DC+ G + E + C C ESC C G ++C C VL
Sbjct: 165 SCRCHMGYQGPLCT-DCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVL 223
Query: 689 HMDDSHCL---HCCNTSDPPSAQECC-------DCQDTTDECI 721
D+ C+ C P SA + C C++ C+
Sbjct: 224 --DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCV 264
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 75.5 bits (184), Expect = 2e-13
Identities = 107/442 (24%), Positives = 148/442 (33%), Gaps = 94/442 (21%)
Query: 250 LHEGRCYSKC-PEGSYAEDGICERCSSPCRTCEGNATN--CHSCEGGH--VLHHGVCQEN 304
LH+G KC P+GS C R C+ C+ C C G + HHG +
Sbjct: 762 LHDGAVACKCHPQGSVGSS--CSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGHHGCHPCH 818
Query: 305 CP---ERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHC 361
C + V CP C + + C C +F CH CP +A+ C
Sbjct: 819 CHPQGSKDTVCDQVTGQCP--CHGEVSGRRCDRCLAGYFGFPS-CHP-CPCNRFAEL--C 872
Query: 362 VPCHKDCLECSG-PKADDCELCLE-------SSWVLYDGLCLEECPAGTYYEKETKE--- 410
P C C G +CE C++ S LC ++ + Y+ +
Sbjct: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLW 932
Query: 411 CRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWD-EDAPGCKPCHVKCF 469
D +CL + C C G NPR S + C+ + D D C +C
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
Query: 470 HCMGPAED-QCQTCPMNSL--LLNTTCVK-----------DCP----------------- 498
C+ + CQ C LN TC + +CP
Sbjct: 993 RCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
Query: 499 -------------EGYYADEDSNRCAHCHSSCRTCEGRHSRQCHS---CRPGWFQLGKEC 542
+GY+ C C RT + H Q C+ G+ GK C
Sbjct: 1053 LPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYG--GKRC 1110
Query: 543 LLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLR-----SKGECHRSC 597
+C+E YY D GRC C+ + G Q P CD + R S C R
Sbjct: 1111 S-ECQENYYGD-PPGRCIPCDCNRAGTQKP------ICDPDTGMCRCREGVSGQRCDRCA 1162
Query: 598 PDHYYVEQSTQTCERCHPTCDQ 619
H Q TC +CH DQ
Sbjct: 1163 RGH---SQEFPTCLQCHLCFDQ 1181
Score = 34.3 bits (77), Expect = 0.50
Identities = 55/237 (23%), Positives = 74/237 (31%), Gaps = 47/237 (19%)
Query: 77 ACDSNCGSCDQNGCYW----CEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCT 132
AC++N D C C G+ + C PG YG C C +C
Sbjct: 971 ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRC-----SCH 1025
Query: 133 GPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTC-NGSATLCT 191
G C G G C+ P +C N + C
Sbjct: 1026 ASGVSP-MECPPG----GGACL------------------CDPVTGACPCLPNVTGLACD 1062
Query: 192 SCPKGAYLL--AQACVS-SCPQGTWPSVRSGSCENCTE--ACAICSGADLCKKCQMQ-PG 245
C G + L + C S C T +S C+ T C + G C +CQ G
Sbjct: 1063 RCADGYWNLVPGRGCQSCDCDPRT---SQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
Query: 246 HPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEG-NATNCHSCEGGHVLHHGVC 301
P GRC + + IC+ + CR EG + C C GH C
Sbjct: 1120 DP----PGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTC 1172
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 74.7 bits (182), Expect = 3e-13
Identities = 93/394 (23%), Positives = 124/394 (31%), Gaps = 77/394 (19%)
Query: 229 AICSGADLCKKCQM--QPGHPLFLHE---GRCYSKCPEGSYAEDGIC-ERCS----SPCR 278
A+C G C + ++ +PG H C +KCP + D C E CS C
Sbjct: 78 AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHGQCE 135
Query: 279 TCEGNATNCHS------CEGGHVLHHGVCQENCPERHVAVKGVCK--------HCPEMCQ 324
G T CH+ CE HG C G C+ C C
Sbjct: 136 DVTGQCT-CHARRWGARCEHACQCQHGTCHPR--------SGACRCEPGWWGAQCASACY 186
Query: 325 DCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECS------GPKADD 378
C C T H +SC +S PC + C G + D
Sbjct: 187 -CSATSRCDPQTGACLCHAGWWGRSCNNQCACNSS---PCEQQSGRCQCRERTFGARCDR 242
Query: 379 CELCLESSWVLYDGLCL-----------EECPAGTYYEKETKECRDCHKSCLTCSSSGTC 427
C DG C E CPAG Y + C C + G C
Sbjct: 243 YCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC 302
Query: 428 TTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSL 487
TC+ G ++ C+ Y + + C PC + H +C C N+
Sbjct: 303 LTCEPGW-----NGTKCDQPCATGFYGEGCSHRCPPC--RDGHACNHVTGKCTRC--NAG 353
Query: 488 LLNTTCVKDCPEGYYADEDSNRCAHCHSS--------CRTCEGRHSRQCH-SCRPGWFQL 538
+ C C G Y ++ + CA C S C G H C+ +C PG
Sbjct: 354 WIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH-- 411
Query: 539 GKECLLQCR-EGYYADNSTGRCERCNRSCKGCQG 571
G +C C D TG C KG G
Sbjct: 412 GADCAQACSCHEDTCDPVTGACHLETNQRKGVMG 445
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/242 (23%), Positives = 73/242 (30%), Gaps = 87/242 (35%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCGSCD--------QNGCYWCEEGFFLLGGSCVRKCGP 110
+C + CP Y C CG C + C CE G+ G C + C
Sbjct: 268 YCREPCPAGFYG-----LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWN--GTKCDQPCAT 320
Query: 111 GFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDIL 170
GFYG E C C C GH C H T
Sbjct: 321 GFYG-------EGCSHRCPPCR-DGH---------------ACNHVT------------- 344
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
C CN A + C + C GT+ E+C CA
Sbjct: 345 -------GKCTRCN------------AGWIGDRCETKCSNGTYG-------EDCAFVCAD 378
Query: 231 CSGADLCK----KCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN 286
C G+ C +C PG +H C CP G + D + CS TC+
Sbjct: 379 C-GSGHCDFQSGRCLCSPG----VHGPHCNVTCPPGLHGAD-CAQACSCHEDTCDPVTGA 432
Query: 287 CH 288
CH
Sbjct: 433 CH 434
Score = 39.3 bits (90), Expect = 0.016
Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 5/81 (6%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C C TY E D G CD Q+G C G G C C PG +G
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVH--GPHCNVTCPPGLHGADCA 416
Query: 119 GECESCHR-ACETCTGPGHDE 138
C SCH C+ TG H E
Sbjct: 417 QAC-SCHEDTCDPVTGACHLE 436
Score = 35.0 bits (79), Expect = 0.30
Identities = 48/197 (24%), Positives = 65/197 (32%), Gaps = 27/197 (13%)
Query: 527 QCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
Q +C GW Q G EC + EG NST C N C RP +C C +F
Sbjct: 60 QVPTCCAGWRQQGDECGIAVCEG----NST--CSE-NEVC-----VRPGEC-RCRHGYF- 105
Query: 587 LRSKGECHRSCPDHYYVEQSTQTCERCHP--TCDQCKGKGALNC----LSCVWSYHLMGG 640
C CP ++ + C CHP C+ G+ + C + G
Sbjct: 106 ---GANCDTKCPRQFWGPDCKELCS-CHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCN 700
C G C+ S P C LC A ++ C CN
Sbjct: 162 TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGAC-LCHAGWWGRSCNNQC--ACN 218
Query: 701 TSDPPSAQECCDCQDTT 717
+S C C++ T
Sbjct: 219 SSPCEQQSGRCQCRERT 235
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 74.7 bits (182), Expect = 3e-13
Identities = 93/394 (23%), Positives = 124/394 (31%), Gaps = 77/394 (19%)
Query: 229 AICSGADLCKKCQM--QPGHPLFLHE---GRCYSKCPEGSYAEDGIC-ERCS----SPCR 278
A+C G C + ++ +PG H C +KCP + D C E CS C
Sbjct: 78 AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHGQCE 135
Query: 279 TCEGNATNCHS------CEGGHVLHHGVCQENCPERHVAVKGVCK--------HCPEMCQ 324
G T CH+ CE HG C G C+ C C
Sbjct: 136 DVTGQCT-CHARRWGARCEHACQCQHGTCHPR--------SGACRCEPGWWGAQCASACY 186
Query: 325 DCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECS------GPKADD 378
C C T H +SC +S PC + C G + D
Sbjct: 187 -CSATSRCDPQTGACLCHAGWWGRSCNNQCACNSS---PCEQQSGRCQCRERTFGARCDR 242
Query: 379 CELCLESSWVLYDGLCL-----------EECPAGTYYEKETKECRDCHKSCLTCSSSGTC 427
C DG C E CPAG Y + C C + G C
Sbjct: 243 YCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC 302
Query: 428 TTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSL 487
TC+ G ++ C+ Y + + C PC + H +C C N+
Sbjct: 303 LTCEPGW-----NGTKCDQPCATGFYGEGCSHRCPPC--RDGHACNHVTGKCTRC--NAG 353
Query: 488 LLNTTCVKDCPEGYYADEDSNRCAHCHSS--------CRTCEGRHSRQCH-SCRPGWFQL 538
+ C C G Y ++ + CA C S C G H C+ +C PG
Sbjct: 354 WIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH-- 411
Query: 539 GKECLLQCR-EGYYADNSTGRCERCNRSCKGCQG 571
G +C C D TG C KG G
Sbjct: 412 GADCAQACSCHEDTCDPVTGACHLETNQRKGVMG 445
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/242 (23%), Positives = 73/242 (30%), Gaps = 87/242 (35%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCGSCD--------QNGCYWCEEGFFLLGGSCVRKCGP 110
+C + CP Y C CG C + C CE G+ G C + C
Sbjct: 268 YCREPCPAGFYG-----LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWN--GTKCDQPCAT 320
Query: 111 GFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDIL 170
GFYG E C C C GH C H T
Sbjct: 321 GFYG-------EGCSHRCPPCR-DGH---------------ACNHVT------------- 344
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
C CN A + C + C GT+ E+C CA
Sbjct: 345 -------GKCTRCN------------AGWIGDRCETKCSNGTYG-------EDCAFVCAD 378
Query: 231 CSGADLCK----KCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN 286
C G+ C +C PG +H C CP G + D + CS TC+
Sbjct: 379 C-GSGHCDFQSGRCLCSPG----VHGPHCNVTCPPGLHGAD-CAQACSCHEDTCDPVTGA 432
Query: 287 CH 288
CH
Sbjct: 433 CH 434
Score = 39.3 bits (90), Expect = 0.016
Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 5/81 (6%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C C TY E D G CD Q+G C G G C C PG +G
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVH--GPHCNVTCPPGLHGADCA 416
Query: 119 GECESCHR-ACETCTGPGHDE 138
C SCH C+ TG H E
Sbjct: 417 QAC-SCHEDTCDPVTGACHLE 436
Score = 35.0 bits (79), Expect = 0.30
Identities = 48/197 (24%), Positives = 65/197 (32%), Gaps = 27/197 (13%)
Query: 527 QCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
Q +C GW Q G EC + EG NST C N C RP +C C +F
Sbjct: 60 QVPTCCAGWRQQGDECGIAVCEG----NST--CSE-NEVC-----VRPGEC-RCRHGYF- 105
Query: 587 LRSKGECHRSCPDHYYVEQSTQTCERCHP--TCDQCKGKGALNC----LSCVWSYHLMGG 640
C CP ++ + C CHP C+ G+ + C + G
Sbjct: 106 ---GANCDTKCPRQFWGPDCKELCS-CHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCN 700
C G C+ S P C LC A ++ C CN
Sbjct: 162 TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGAC-LCHAGWWGRSCNNQC--ACN 218
Query: 701 TSDPPSAQECCDCQDTT 717
+S C C++ T
Sbjct: 219 SSPCEQQSGRCQCRERT 235
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 69.3 bits (168), Expect = 1e-11
Identities = 77/288 (26%), Positives = 104/288 (36%), Gaps = 57/288 (19%)
Query: 320 PEMCQD---CIHEKTCKECTPEFFLHDDMCHQSCPRGFYA-DSRHCVPCHKDCLECSGPK 375
P+ CQ C+ C+ C P FF C CP ++ D R PCH +C P
Sbjct: 60 PDACQKDEVCVKPGLCR-CKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHG-QCE-PA 114
Query: 376 ADDCELCLESSWVLYDGLCLEECPAGTY--YEKETKECR--------DCHKSCLTCSSSG 425
C+ C W C C G + + T C C + C +++
Sbjct: 115 TGACQ-CQADRW---GARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 426 TCTTCQKGLIMNP-----RGSCMANEKCSPSEYWDEDAPGCKP------CHVKCFHCMG- 473
C + P R S N SP E D C+P C +C G
Sbjct: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQ-DSGRCACRPGWWGPECQQQCECVRGR 229
Query: 474 --PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH---------SSCRTCE- 521
A +C TCP C CP G + + ++ C C SC +CE
Sbjct: 230 CSAASGEC-TCPPG--FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 522 GRHSRQCHS-CRPGWFQLGKECLLQC---REGYYADNSTGRCERCNRS 565
G + QC C PG F G+ C QC R G + TG C+RC+ S
Sbjct: 287 GWNGTQCQQPCLPGTF--GESCEQQCPHCRHGEACEPDTGHCQRCSGS 332
Score = 56.2 bits (134), Expect = 1e-07
Identities = 79/342 (23%), Positives = 107/342 (31%), Gaps = 78/342 (22%)
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEGLQLLR-GMC--------VHATKTQEEGKFWN 167
E+ C + + CT P + +CQ+ ++ G+C H + ++ G++W
Sbjct: 38 ELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCPGQYWG 96
Query: 168 DILRKLQPC--HSSCKTCNGSATL------------CTSCPKGAYLLAQACVSSCPQGTW 213
R+ PC H C+ G+ C P G A V C G W
Sbjct: 97 PDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG-VCHCEPGWW 155
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERC 273
S C+ C A A C A G C C G + RC
Sbjct: 156 SSTCRRPCQ-CNTAAARCEQA-----------------TGACV--CKPGWWG-----RRC 190
Query: 274 SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCK 333
S C C G+ C G G C ++ V+G C C
Sbjct: 191 SFRC-NCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC---------- 237
Query: 334 ECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECS-----GPKADDCELCLESSWV 388
C P F C CP G H V C C C P CE C E W
Sbjct: 238 TCPPGF--RGARCELPCPAG-----SHGVQCAHSCGRCKHNEPCSPDTGSCESC-EPGW- 288
Query: 389 LYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTC 430
C + C GT+ E ++C C +G C C
Sbjct: 289 -NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/333 (20%), Positives = 104/333 (31%), Gaps = 71/333 (21%)
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---------CQMQP 244
PKG ++ CV+S P ++ IC G D C+K C+ +P
Sbjct: 24 PKGQHV----CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
Query: 245 GHPLFLHEGRCYSKCPEGSYAED----------GICERCSSPCRTCEGN--ATNCH-SCE 291
G C S+CP + D G CE + C+ C+ + C C
Sbjct: 80 G----FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ-CQADRWGARCEFPCA 134
Query: 292 GGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCP 351
G HG C H C CQ C++ T + C
Sbjct: 135 CGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191
Query: 352 RGFYADSRHCVPCHKDCLECS------GPKADDCELCLESSWVLYDGLCL---------- 395
+ + H PC +D C+ GP+ C+ G C
Sbjct: 192 ---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
Query: 396 -EECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
CPAG++ + C C + +G+C +C+ G + C P +
Sbjct: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW-----NGTQCQQPCLPGTFG 303
Query: 455 DEDAPGCKPCHVKCFHC-----MGPAEDQCQTC 482
+ C +C HC P CQ C
Sbjct: 304 ES-------CEQQCPHCRHGEACEPDTGHCQRC 329
Score = 38.1 bits (87), Expect = 0.035
Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 21/93 (22%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCGSCDQN--------GCYWCEEGFFLLGGSCVRKCGPG 111
C CP ++ C +CG C N C CE G+ G C + C PG
Sbjct: 248 CELPCPAGSHGVQ-----CAHSCGRCKHNEPCSPDTGSCESCEPGWN--GTQCQQPCLPG 300
Query: 112 FYGDQEMGECESCH--RACETCTGPGHDECSSC 142
+G+ +C C ACE TG C C
Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTG----HCQRC 329
Score = 36.2 bits (82), Expect = 0.13
Identities = 50/202 (24%), Positives = 67/202 (33%), Gaps = 44/202 (21%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNC----GSCDQNGCYWCEEGFFLL---GGSCVRK---- 107
HC T +C + C G+C +W F G C +
Sbjct: 149 HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRC 208
Query: 108 -CGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW 166
C PG++G + +CE C +G EC +C G + R C G
Sbjct: 209 ACRPGWWGPECQQQCECVRGRCSAASG----EC-TCPPGFRGAR--CELPCPAGSHG--- 258
Query: 167 NDILRKLQPCHS--SCK---TCNGSATLCTSCPKGAYLLAQACVSSCPQGTW-------- 213
+Q HS CK C+ C SC G C C GT+
Sbjct: 259 ------VQCAHSCGRCKHNEPCSPDTGSCESCEPG--WNGTQCQQPCLPGTFGESCEQQC 310
Query: 214 PSVRSG-SCENCTEACAICSGA 234
P R G +CE T C CSG+
Sbjct: 311 PHCRHGEACEPDTGHCQRCSGS 332
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 68.6 bits (166), Expect = 2e-11
Identities = 103/439 (23%), Positives = 163/439 (37%), Gaps = 115/439 (26%)
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQ--MQPGHPLFLHE--GRCYSKCPEGSYAEDGI 269
P+V +C C G CK C+ +Q F + G+C+ C +G YA
Sbjct: 796 PNVVGRTCNRCAPG-TFGFGPSGCKPCECHLQGSVNAFCNPVTGQCH--CFQGVYARQ-- 850
Query: 270 CERC---------SSPCRTCEGNATNC----------------HSCE-------GGHVLH 297
C+RC PC+ C G+A +C H+CE G ++
Sbjct: 851 CDRCLPGHWGFPSCQPCQ-CNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIG 909
Query: 298 HGV-CQE-NCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFY 355
G C+ CP+ + + + C QD + + C P + C C G++
Sbjct: 910 SGDHCRPCPCPDGPDSGRQFARSC---YQDPVTLQLACVCDPGYI--GSRC-DDCASGYF 963
Query: 356 ADSRH----CVPCH-KDCLECSGPKADDCEL--CLESSWVLYDGLCLEECPAGTYYEKET 408
+ C PC + ++ + P+A D E CL+ + C + C G Y +
Sbjct: 964 GNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC-QFCRFGYYGDALQ 1022
Query: 409 KECRDC---HKSCLTCSSSGTCTTCQKGLIMNPRGSCMAN------EKCSPSEYWDEDAP 459
++CR C + + +G+ C K + C+ N ++C+P+ +
Sbjct: 1023 QDCRKCVCNYLGTVQEHCNGSDCQCDKA---TGQCLCLPNVIGQNCDRCAPNTWQLASGT 1079
Query: 460 GCKPCHVKCFHCMGPA----EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHS 515
GC PC+ H GP+ QCQ P TC +C E ++ D D
Sbjct: 1080 GCDPCNCNAAHSFGPSCNEFTGQCQCMPGFG---GRTC-SECQELFWGDPD--------V 1127
Query: 516 SCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRC--------ERCNRSCK 567
CR C+ C P + QC D STG+C RC++ +
Sbjct: 1128 ECRACD---------CDPRGIETP-----QC------DQSTGQCVCVEGVEGPRCDKCTR 1167
Query: 568 GCQGPRPTDCLSCDRFFFL 586
G G P DC C + F L
Sbjct: 1168 GYSGVFP-DCTPCHQCFAL 1185
Score = 48.9 bits (115), Expect = 2e-05
Identities = 101/451 (22%), Positives = 148/451 (32%), Gaps = 126/451 (27%)
Query: 43 PVQKQIHLKCGNRFDHHCYKTCPEKTYSEAVECKACDSNCGSCDQ--NGCYWCEEGFFLL 100
PV Q H G + C + P + + C+ + CD C C++ + +
Sbjct: 835 PVTGQCHCFQGV-YARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQD--YTM 891
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGP--GHDECSSCQEGLQLLRGMCVHATK 158
G +C R C G+YGD +G + C R C GP G SC + L+ CV
Sbjct: 892 GHNCER-CLAGYYGDPIIGSGDHC-RPCPCPDGPDSGRQFARSCYQDPVTLQLACV---- 945
Query: 159 TQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRS 218
P + + C C G + G PS
Sbjct: 946 --------------CDPGYIGSR--------CDDCASGYF------------GN-PSEVG 970
Query: 219 GSCENC----------TEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDG 268
GSC+ C EAC +G C KC L+ EG C G Y
Sbjct: 971 GSCQPCQCHNNIDTTDPEACDKETGR--CLKC-------LYHTEGEHCQFCRFGYYG--- 1018
Query: 269 ICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIH 328
+ CR C N + G QE+C C +C +
Sbjct: 1019 --DALQQDCRKCVCN-------------YLGTVQEHCNGSDCQCDKATGQC--LCLPNVI 1061
Query: 329 EKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADD----CELCLE 384
+ C C P + A C PC+ + GP ++ C+ C+
Sbjct: 1062 GQNCDRCAPNTWQ-------------LASGTGCDPCNCNAAHSFGPSCNEFTGQCQ-CMP 1107
Query: 385 SSWVLYDGLCLEECPAGTYYEKETKECRDCH------KSCLTCSSSGTCTTCQKGLIMNP 438
+ G EC ++ ECR C ++ S+G C C +G + P
Sbjct: 1108 G----FGGRTCSECQE-LFWGDPDVECRACDCDPRGIETPQCDQSTGQC-VCVEG-VEGP 1160
Query: 439 RGSCMANEKCSPSEYWDEDAPGCKPCHVKCF 469
R C +KC+ + P C PCH +CF
Sbjct: 1161 R--C---DKCTRG--YSGVFPDCTPCH-QCF 1183
Score = 43.9 bits (102), Expect = 6e-04
Identities = 73/331 (22%), Positives = 107/331 (32%), Gaps = 108/331 (32%)
Query: 474 PAEDQCQTC--PMNSLLLNTTCVKDC-PEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHS 530
P D C+ +++LL T +C P+G S+ C C+ R C+
Sbjct: 750 PMTDVCRNIIFSISALLHQTGLACECDPQGSL----SSVCDPNGGQCQCRPNVVGRTCNR 805
Query: 531 CRPGWFQLGK------ECLLQCREGYYADNSTGRC--------ERCNR---------SCK 567
C PG F G EC LQ + + TG+C +C+R SC+
Sbjct: 806 CAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQ 865
Query: 568 GCQ--------GPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHP-TCD 618
CQ P +CL+C + + G C YY + + + C P C
Sbjct: 866 PCQCNGHADDCDPVTGECLNCQDY-----TMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
Query: 619 QCKGKG---ALNC--------LSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCH-- 665
G A +C L+CV +G C DC G + +C+ C
Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRC-DDCASGYFGNPSEVGGSCQPCQCH 979
Query: 666 --------ESCMECKGPGAKNCTLCPANLVLHMDDSHCLHC------------------- 698
E+C + G C C + H + HC C
Sbjct: 980 NNIDTTDPEACDKETG----RCLKC----LYHTEGEHCQFCRFGYYGDALQQDCRKCVCN 1031
Query: 699 --------CNTSDPPSAQECCDCQDTTDECI 721
CN SD C C T +C+
Sbjct: 1032 YLGTVQEHCNGSD-------CQCDKATGQCL 1055
Score = 42.4 bits (98), Expect = 0.002
Identities = 71/318 (22%), Positives = 103/318 (32%), Gaps = 78/318 (24%)
Query: 252 EGRCYSKCPEGSYAEDGICERCSS-----PCRTCEGNATNCHSCEGGHVLHHGVCQENCP 306
EG + C + CE C P R EG N ++C+ + H +
Sbjct: 291 EGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGR--NSNACKKCNCNEHSISCHFDM 348
Query: 307 ERHVAVKGVCKHCPEMCQDCIHE---KTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVP 363
++A V +C DC H + C++C P ++ H P D C
Sbjct: 349 AVYLATGNVSGG---VCDDCQHNTMGRNCEQCKPFYYQH--------PERDIRDPNFCER 397
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSS 423
C C C+ + S L G C C E + C C + SS
Sbjct: 398 C--TCDPAGSQNEGICDSYTDFSTGLIAGQC--RCKLNV----EGEHCDVCKEGFYDLSS 449
Query: 424 SGT--CTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQT 481
C +C NP G+ PG PC + HC
Sbjct: 450 EDPFGCKSC----ACNPLGT----------------IPGGNPCDSETGHCY--------- 480
Query: 482 CPMNSLLLNTTCVKDCPEGYYADEDSNRCAHC--------HSSCRTCEGRHSRQCHSCRP 533
L+ C + PE + D + C C ++SC S QC SCRP
Sbjct: 481 --CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFA----ESGQC-SCRP 533
Query: 534 GWFQLGKECLLQCREGYY 551
+G++C + GYY
Sbjct: 534 --HMIGRQC-NEVEPGYY 548
Score = 37.0 bits (84), Expect = 0.078
Identities = 56/251 (22%), Positives = 81/251 (32%), Gaps = 61/251 (24%)
Query: 439 RGSCMAN---EKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVK 495
RG+C +C+P + ++E+ G H C H C+ C
Sbjct: 268 RGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRH--NTKGLNCELC--------MDFYH 317
Query: 496 DCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNS 555
D P +SN C C+ + HS CH + G + S
Sbjct: 318 DLPWRPAEGRNSNACKKCNCN------EHSISCHFDMAVYLATG-------------NVS 358
Query: 556 TGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHP 615
G C+ C + G +C C F++ R D + CERC
Sbjct: 359 GGVCDDCQHNTMG------RNCEQCKPFYY-----QHPERDIRDPNF-------CERC-- 398
Query: 616 TCDQCKGKGALNCLSCV-WSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGP 674
TCD + C S +S L+ G C V EGE +C+ C E +
Sbjct: 399 TCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNV------EGE--HCDVCKEGFYDLSSE 450
Query: 675 GAKNCTLCPAN 685
C C N
Sbjct: 451 DPFGCKSCACN 461
>gi|84490388 R-spondin1 [Homo sapiens]
Length = 263
Score = 66.6 bits (161), Expect = 9e-11
Identities = 53/179 (29%), Positives = 69/179 (38%), Gaps = 39/179 (21%)
Query: 174 QPCHSSCKTCNGSATLCTSCPKGAYLLAQ--------ACVSSCPQGTWPSVRS--GSCEN 223
Q C C+ C+ C C ++L + C+ SCP G + + C
Sbjct: 38 QACAKGCELCS-EVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIK 96
Query: 224 CT-EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCR---- 278
C E C C + C KC+ L+LH+GRCY CPEGS A +G E CSSP +
Sbjct: 97 CKIEHCEACFSHNFCTKCK----EGLYLHKGRCYPACPEGSSAANGTME-CSSPAQCEMS 151
Query: 279 ------TCEGNATNCHSCEGG-----HVLH-----HGVCQENCPERHVAVKGVCKHCPE 321
C C G VLH H C + R V+ V CPE
Sbjct: 152 EWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRRV--PCPE 208
Score = 53.5 bits (127), Expect = 8e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 76 KACDSNCGSCDQ-NGCYWCEEGFFLL--------GGSCVRKCGPGFYG--DQEMGECESC 124
+AC C C + NGC C F+L G C+ C PG++ + +M +C C
Sbjct: 38 QACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKC 97
Query: 125 H-RACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
CE C H+ C+ C+EGL L +G C A
Sbjct: 98 KIEHCEACFS--HNFCTKCKEGLYLHKGRCYPA 128
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 24/130 (18%)
Query: 271 ERCSSPCRTCEGNATNCHSC--------EGGHVLHHGVCQENCPERHVAVKGV----CKH 318
+ C+ C C C C E + GVC +CP + + C
Sbjct: 38 QACAKGCELCS-EVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIK 96
Query: 319 CP-EMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKAD 377
C E C+ C C +C +LH C+ +CP G A + +ECS P
Sbjct: 97 CKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAAN--------GTMECSSPA-- 146
Query: 378 DCELCLESSW 387
CE+ S W
Sbjct: 147 QCEMSEWSPW 156
Score = 46.6 bits (109), Expect = 1e-04
Identities = 42/147 (28%), Positives = 62/147 (42%), Gaps = 33/147 (22%)
Query: 353 GFYADSRHCVPCHK--DCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKE 410
G A ++ C C + CL+CS PK + LE + + G+CL CP G Y++ +
Sbjct: 36 GSQACAKGCELCSEVNGCLKCS-PKLF---ILLERNDIRQVGVCLPSCPPG-YFDARNPD 90
Query: 411 CRDCHKS----CLTCSSSGTCTTCQKGLIMN--------PRGSCMAN---EKCSPSEYWD 455
C K C C S CT C++GL ++ P GS AN E SP++
Sbjct: 91 MNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMECSSPAQ--- 147
Query: 456 EDAPGCKPCHVKCFHCMGPAEDQCQTC 482
C + + GP + Q C
Sbjct: 148 --------CEMSEWSPWGPCSKKQQLC 166
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/145 (26%), Positives = 51/145 (35%), Gaps = 23/145 (15%)
Query: 419 LTCSSSGTCTTCQKGLIMNPRGSCMAN-EKCSPSEYWDEDAPGCKPCHVKCFHCMGPAED 477
LT SS G Q+ + +C E CS + GC C K F +
Sbjct: 17 LTISSRGIKGKRQRRISAEGSQACAKGCELCS-------EVNGCLKCSPKLFILL----- 64
Query: 478 QCQTCPMNSLLLNTTCVKDCPEGYY--ADEDSNRCAHCH-SSCRTCEGRHSRQCHSCRPG 534
N + C+ CP GY+ + D N+C C C C + C C+ G
Sbjct: 65 -----ERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNF--CTKCKEG 117
Query: 535 WFQLGKECLLQCREGYYADNSTGRC 559
+ C C EG A N T C
Sbjct: 118 LYLHKGRCYPACPEGSSAANGTMEC 142
Score = 35.8 bits (81), Expect = 0.17
Identities = 32/135 (23%), Positives = 48/135 (35%), Gaps = 20/135 (14%)
Query: 487 LLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKE----- 541
L +++ +K + + E S CA C G C C P F L +
Sbjct: 17 LTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNG-----CLKCSPKLFILLERNDIRQ 71
Query: 542 ---CLLQCREGYY--ADNSTGRCERCN-RSCKGCQGPRPTDCLSCDRFFFLLRSKGECHR 595
CL C GY+ + +C +C C+ C C C +L KG C+
Sbjct: 72 VGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHN--FCTKCKEGLYL--HKGRCYP 127
Query: 596 SCPDHYYVEQSTQTC 610
+CP+ T C
Sbjct: 128 ACPEGSSAANGTMEC 142
Score = 35.0 bits (79), Expect = 0.30
Identities = 27/100 (27%), Positives = 38/100 (38%), Gaps = 11/100 (11%)
Query: 60 CYKTCPEKTY-------SEAVECKACDSNCGSC-DQNGCYWCEEGFFLLGGSCVRKCGPG 111
C +CP + ++ ++CK +C +C N C C+EG +L G C C G
Sbjct: 75 CLPSCPPGYFDARNPDMNKCIKCKI--EHCEACFSHNFCTKCKEGLYLHKGRCYPACPEG 132
Query: 112 FYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRG 151
EC S CE CS Q+ RG
Sbjct: 133 SSAANGTMECSS-PAQCEMSEWSPWGPCSKKQQLCGFRRG 171
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 66.2 bits (160), Expect = 1e-10
Identities = 122/513 (23%), Positives = 172/513 (33%), Gaps = 129/513 (25%)
Query: 192 SCPKGAYLLAQACVSSCPQG--------TWPSVR-------SGSCENC-----TEACAIC 231
S P + A V CP G WP R G CE C E+C
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDV 769
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAE-----DGICERCSSPCRTCEGN-AT 285
+G C C+ G P KC G Y E C+ C+ P N +
Sbjct: 770 TGE--CLNCKDHTGGPYC-------DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSP 820
Query: 286 NCHS-------CEGGHVLHHGVCQENCPERHVAVKGV----CKHCPEMCQDCIH------ 328
CH C+G V + G E C E + V C+ C C D +
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC--QCNDNLDFSIPGS 878
Query: 329 ----EKTCKECTPEFFLHDDMCHQSCPRGFYADS---RHCVPCHKDC----LECSGPKAD 377
+C C P C + C G++ D+ ++C PC + E +
Sbjct: 879 CDSLSGSCLICKPG--TTGRYC-ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG 935
Query: 378 DCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCH-----KSCLTCSSSGTCTTCQK 432
CE C + G ++C AGT+ + + C C+ C SG C CQ
Sbjct: 936 QCE-CRAN----VQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCW-CQP 989
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC---MGPAEDQCQTCPMNSLLL 489
G+ C Y++ GC C +C H P +C CP N++
Sbjct: 990 GVTGKKCDRCAHG-------YFNFQEGGCTAC--ECSHLGNNCDPKTGRC-ICPPNTI-- 1037
Query: 490 NTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCH------SCRPGWFQLGKECL 543
C K C + + C C+ C T G QC+ +C P + G +C
Sbjct: 1038 GEKCSK-CAPNTWGHSITTGCKACN--CSTV-GSLDFQCNVNTGQCNCHPKFS--GAKCT 1091
Query: 544 LQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHY-- 601
+C G++ + RC C+ G TD +CD +C SC D
Sbjct: 1092 -ECSRGHW---NYPRCNLCDCFLPG------TDATTCDS------ETKKC--SCSDQTGQ 1133
Query: 602 ---YVEQSTQTCERCHPTCDQCKGKGALNCLSC 631
V C+RC P K L C SC
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 63.9 bits (154), Expect = 6e-10
Identities = 118/535 (22%), Positives = 163/535 (30%), Gaps = 176/535 (32%)
Query: 78 CDSNCGSCDQ--NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPG 135
C + SCD C C++ GG KC PGFYG+ G E C P
Sbjct: 759 CFGHAESCDDVTGECLNCKDH---TGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPS 815
Query: 136 HDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPK 195
++ +C L +C CP
Sbjct: 816 NNFSPTCHLDRSL--------------------------------------GLICDGCPV 837
Query: 196 GAYLLAQACVSSCPQGTW--PSVRSGSCENC----------TEACAICSGADLCKKCQMQ 243
G C C +G + PSV GSC+ C +C SG+ C C +
Sbjct: 838 G--YTGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGS--CLIC--K 890
Query: 244 PGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN--CHSCEGGHVLHHGVC 301
PG GR C +G Y D + + PCR G + + CHS G C
Sbjct: 891 PG-----TTGRYCELCADG-YFGDAVDAKNCQPCRCNAGGSFSEVCHS-------QTGQC 937
Query: 302 QENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHC 361
+ C+ + + C +C F +R C
Sbjct: 938 E--------------------CRANVQGQRCDKCKAGTF-------------GLQSARGC 964
Query: 362 VPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTC 421
VPC+ + G K+ DCE G C C G K+C C
Sbjct: 965 VPCNCNSF---GSKSFDCE---------ESGQCW--CQPGV----TGKKCDRCAHGYFNF 1006
Query: 422 SSSGTCTTCQKGLIMN----PRGSCMAN--------EKCSPSEYWDEDAPGCKPCHVKCF 469
G CT C+ + N G C+ KC+P+ + GCK C+
Sbjct: 1007 QEGG-CTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCS-- 1063
Query: 470 HCMGPAEDQCQT----CPMNSLLLNTTCVKDCPEGYYADEDSNRC---------AHCHSS 516
+G + QC C + C +C G++ N C C S
Sbjct: 1064 -TVGSLDFQCNVNTGQCNCHPKFSGAKCT-ECSRGHWNYPRCNLCDCFLPGTDATTCDSE 1121
Query: 517 CRTC---------------EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST 556
+ C EG H C CRPG F L + L C Y +T
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIH---CDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173
Score = 48.5 bits (114), Expect = 3e-05
Identities = 54/232 (23%), Positives = 84/232 (36%), Gaps = 34/232 (14%)
Query: 75 CKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG----ECESCHRACET 130
C + S C+++G WC+ G + G C R C G++ QE G EC C+
Sbjct: 969 CNSFGSKSFDCEESGQCWCQPG--VTGKKCDR-CAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 131 CTG----PGH---DECSSCQE---GLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
TG P + ++CS C G + G T F ++ CH
Sbjct: 1026 KTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKF 1085
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
S CT C +G + + + C P + +C++ T+ C+ C C
Sbjct: 1086 -----SGAKCTECSRGHWNYPRCNLCDC---FLPGTDATTCDSETKKCSCSDQTGQC-TC 1136
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEG 292
++ EG +C G + D S C C G T C +G
Sbjct: 1137 KVNV-------EGIHCDRCRPGKFGLDAKNPLGCSSC-YCFGTTTQCSEAKG 1180
Score = 38.1 bits (87), Expect = 0.035
Identities = 52/253 (20%), Positives = 76/253 (30%), Gaps = 58/253 (22%)
Query: 348 QSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKE 407
++CP + C H C D C+ C G + AGT+ K
Sbjct: 294 RACPLDPATNKSRCECEHNTC-------GDSCDQCCP-------GFHQKPWRAGTFLTKT 339
Query: 408 TKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
E +CH C ++ L +N RG + C + C+ C
Sbjct: 340 ECEACNCHGKAEECYYDEN--VARRNLSLNIRGKYIGGGVCINCTQ-NTAGINCETCTDG 396
Query: 468 CFHCMGPAEDQ---CQTCPMNSL-LLNTTCVKD--------------------------C 497
F G + + CQ C + + LN CVKD C
Sbjct: 397 FFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRC 456
Query: 498 PEGYYADEDSNRCA----------HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCR 547
GY D C C C E C C+ G+F L ++ C
Sbjct: 457 ARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 548 EGYYADNSTGRCE 560
E + + RC+
Sbjct: 517 E-CFCSGVSNRCQ 528
Score = 36.6 bits (83), Expect = 0.10
Identities = 44/179 (24%), Positives = 63/179 (35%), Gaps = 45/179 (25%)
Query: 128 CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPC----HSS---- 179
C+ G C +C G LR +Q G+ L PC HSS
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLR--------SQPGGRTPGPTLGTCVPCQCNGHSSLCDP 1431
Query: 180 ----CKTC--NGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
C+ C + + C C G Y + + + C Q P + S + N + +C + G
Sbjct: 1432 ETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSN--NFSPSC-VAEG 1488
Query: 234 ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGN-ATNCHSCE 291
D + RC + CP G E CERC+ GN +C CE
Sbjct: 1489 LD----------------DYRC-TACPRG--YEGQYCERCAPGYTGSPGNPGGSCQECE 1528
Score = 35.4 bits (80), Expect = 0.23
Identities = 54/219 (24%), Positives = 74/219 (33%), Gaps = 72/219 (32%)
Query: 262 GSYAEDGICERCSSPCRTCEGNATNCHSCEG-----------GHVLHHGVCQ-------- 302
G++ CE C+ C G A C+ E G + GVC
Sbjct: 333 GTFLTKTECEACN-----CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 303 ---ENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMC---HQSCPRGFYA 356
E C + KGV + P CQ C C P L +++C + RG
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPC-------HCDPIGSL-NEVCVKDEKHARRGLAP 439
Query: 357 DSRHC------VPC---------HKDCLECS----GPKADD-----CELCLESSWVLYDG 392
S HC V C + DC C+ G K +D C +C E+ +G
Sbjct: 440 GSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPC-ICKEN----VEG 494
Query: 393 LCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQ 431
C +G + +E D K C C SG CQ
Sbjct: 495 GDCSRCKSGFFNLQE-----DNWKGCDECFCSGVSNRCQ 528
Score = 35.0 bits (79), Expect = 0.30
Identities = 61/261 (23%), Positives = 79/261 (30%), Gaps = 61/261 (23%)
Query: 60 CY---KTCPEKTYSEAVECKACDSNCG-SCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
CY + CP + C+ + CG SCDQ C PGF+
Sbjct: 289 CYGHARACPLDPATNKSRCECEHNTCGDSCDQ--------------------CCPGFHQK 328
Query: 116 QEMG-------ECESC--HRACETC---TGPGHDECSSCQEGLQLLRGMCVHATK----- 158
ECE+C H E C S G + G+C++ T+
Sbjct: 329 PWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGI 388
Query: 159 ---TQEEGKFWN-----DILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQ 210
T +G F + R QPCH C +C K A C
Sbjct: 389 NCETCTDGFFRPKGVSPNYPRPCQPCH--CDPIGSLNEVCVKDEKHARRGLAPGSCHCKT 446
Query: 211 GTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGIC 270
G SC+ C +G CK C +E C+ C E G C
Sbjct: 447 G----FGGVSCDRCARGY---TGYPDCKACNCSGLGSK--NEDPCFGPCICKENVEGGDC 497
Query: 271 ERCSSP-CRTCEGNATNCHSC 290
RC S E N C C
Sbjct: 498 SRCKSGFFNLQEDNWKGCDEC 518
Score = 34.3 bits (77), Expect = 0.50
Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 52/179 (29%)
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN------CLS 630
C +C F+ LRS+ P + TC C QC G +L C +
Sbjct: 1391 CEACLPGFYRLRSQPGGRTPGP-------TLGTCVPC-----QCNGHSSLCDPETSICQN 1438
Query: 631 CVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKC-----------HESCMECKGPGAKNC 679
C +H G C C +G Y + +G +C++C SC+ +G C
Sbjct: 1439 C--QHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCV-AEGLDDYRC 1494
Query: 680 TLCPANLVLHMDDSHCLHCC--NTSDP----PSAQEC-CD--------CQDTTDECILR 723
T CP + +C C T P S QEC CD C T C R
Sbjct: 1495 TACPRG----YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549
Score = 30.8 bits (68), Expect = 5.6
Identities = 62/280 (22%), Positives = 83/280 (29%), Gaps = 74/280 (26%)
Query: 268 GICERCSSPCRTCEGN-ATNCHSCEGGHVLHHGVCQENCPERH--------VAVKGVCK- 317
G+C C R C + ATN CE H C + CP H K C+
Sbjct: 285 GMCI-CYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 318 -HCPEMCQDCIHEK-------------------TCKECTPEFFLHDDMCHQSCPRGFYAD 357
+C ++C +++ C CT + ++C GF+
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQN---TAGINCETCTDGFFRP 400
Query: 358 S-------RHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKE 410
R C PCH D P E+C++ GL C
Sbjct: 401 KGVSPNYPRPCQPCHCD------PIGSLNEVCVKDEKHARRGLAPGSC------------ 442
Query: 411 CRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFH 470
C T +C C +G P C A CS +ED PC C
Sbjct: 443 ------HCKTGFGGVSCDRCARGYTGYP--DCKAC-NCSGLGSKNED-----PCFGPCIC 488
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRC 510
C C L K C E + SNRC
Sbjct: 489 KENVEGGDCSRCKSGFFNLQEDNWKGCDE-CFCSGVSNRC 527
Score = 30.4 bits (67), Expect = 7.3
Identities = 40/165 (24%), Positives = 52/165 (31%), Gaps = 47/165 (28%)
Query: 441 SCMANEKCSPSEYWDEDAPG----------CKPCHVKCFHCM-GPAEDQCQTCPMNSLLL 489
S ++ E C P Y PG C PC + P CQ C ++
Sbjct: 1387 SGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTA-- 1444
Query: 490 NTTCVKDCPEGYYA-----DEDSNRCA--------HCHSSCRTCEGRHSRQCHSCRPGWF 536
C + C GYY D +CA + SC EG +C +C G+
Sbjct: 1445 GDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC-VAEGLDDYRCTACPRGY- 1501
Query: 537 QLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
EG Y CERC G G C C+
Sbjct: 1502 -----------EGQY-------CERCAPGYTGSPGNPGGSCQECE 1528
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 66.2 bits (160), Expect = 1e-10
Identities = 122/513 (23%), Positives = 172/513 (33%), Gaps = 129/513 (25%)
Query: 192 SCPKGAYLLAQACVSSCPQG--------TWPSVR-------SGSCENC-----TEACAIC 231
S P + A V CP G WP R G CE C E+C
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDV 769
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAE-----DGICERCSSPCRTCEGN-AT 285
+G C C+ G P KC G Y E C+ C+ P N +
Sbjct: 770 TGE--CLNCKDHTGGPYC-------DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSP 820
Query: 286 NCHS-------CEGGHVLHHGVCQENCPERHVAVKGV----CKHCPEMCQDCIH------ 328
CH C+G V + G E C E + V C+ C C D +
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC--QCNDNLDFSIPGS 878
Query: 329 ----EKTCKECTPEFFLHDDMCHQSCPRGFYADS---RHCVPCHKDC----LECSGPKAD 377
+C C P C + C G++ D+ ++C PC + E +
Sbjct: 879 CDSLSGSCLICKPG--TTGRYC-ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG 935
Query: 378 DCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCH-----KSCLTCSSSGTCTTCQK 432
CE C + G ++C AGT+ + + C C+ C SG C CQ
Sbjct: 936 QCE-CRAN----VQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCW-CQP 989
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC---MGPAEDQCQTCPMNSLLL 489
G+ C Y++ GC C +C H P +C CP N++
Sbjct: 990 GVTGKKCDRCAHG-------YFNFQEGGCTAC--ECSHLGNNCDPKTGRC-ICPPNTI-- 1037
Query: 490 NTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCH------SCRPGWFQLGKECL 543
C K C + + C C+ C T G QC+ +C P + G +C
Sbjct: 1038 GEKCSK-CAPNTWGHSITTGCKACN--CSTV-GSLDFQCNVNTGQCNCHPKFS--GAKCT 1091
Query: 544 LQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHY-- 601
+C G++ + RC C+ G TD +CD +C SC D
Sbjct: 1092 -ECSRGHW---NYPRCNLCDCFLPG------TDATTCDS------ETKKC--SCSDQTGQ 1133
Query: 602 ---YVEQSTQTCERCHPTCDQCKGKGALNCLSC 631
V C+RC P K L C SC
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 63.9 bits (154), Expect = 6e-10
Identities = 118/535 (22%), Positives = 163/535 (30%), Gaps = 176/535 (32%)
Query: 78 CDSNCGSCDQ--NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPG 135
C + SCD C C++ GG KC PGFYG+ G E C P
Sbjct: 759 CFGHAESCDDVTGECLNCKDH---TGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPS 815
Query: 136 HDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPK 195
++ +C L +C CP
Sbjct: 816 NNFSPTCHLDRSL--------------------------------------GLICDGCPV 837
Query: 196 GAYLLAQACVSSCPQGTW--PSVRSGSCENC----------TEACAICSGADLCKKCQMQ 243
G C C +G + PSV GSC+ C +C SG+ C C +
Sbjct: 838 G--YTGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGS--CLIC--K 890
Query: 244 PGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN--CHSCEGGHVLHHGVC 301
PG GR C +G Y D + + PCR G + + CHS G C
Sbjct: 891 PG-----TTGRYCELCADG-YFGDAVDAKNCQPCRCNAGGSFSEVCHS-------QTGQC 937
Query: 302 QENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHC 361
+ C+ + + C +C F +R C
Sbjct: 938 E--------------------CRANVQGQRCDKCKAGTF-------------GLQSARGC 964
Query: 362 VPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTC 421
VPC+ + G K+ DCE G C C G K+C C
Sbjct: 965 VPCNCNSF---GSKSFDCE---------ESGQCW--CQPGV----TGKKCDRCAHGYFNF 1006
Query: 422 SSSGTCTTCQKGLIMN----PRGSCMAN--------EKCSPSEYWDEDAPGCKPCHVKCF 469
G CT C+ + N G C+ KC+P+ + GCK C+
Sbjct: 1007 QEGG-CTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCS-- 1063
Query: 470 HCMGPAEDQCQT----CPMNSLLLNTTCVKDCPEGYYADEDSNRC---------AHCHSS 516
+G + QC C + C +C G++ N C C S
Sbjct: 1064 -TVGSLDFQCNVNTGQCNCHPKFSGAKCT-ECSRGHWNYPRCNLCDCFLPGTDATTCDSE 1121
Query: 517 CRTC---------------EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST 556
+ C EG H C CRPG F L + L C Y +T
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIH---CDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173
Score = 48.5 bits (114), Expect = 3e-05
Identities = 54/232 (23%), Positives = 84/232 (36%), Gaps = 34/232 (14%)
Query: 75 CKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG----ECESCHRACET 130
C + S C+++G WC+ G + G C R C G++ QE G EC C+
Sbjct: 969 CNSFGSKSFDCEESGQCWCQPG--VTGKKCDR-CAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 131 CTG----PGH---DECSSCQE---GLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
TG P + ++CS C G + G T F ++ CH
Sbjct: 1026 KTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKF 1085
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
S CT C +G + + + C P + +C++ T+ C+ C C
Sbjct: 1086 -----SGAKCTECSRGHWNYPRCNLCDC---FLPGTDATTCDSETKKCSCSDQTGQC-TC 1136
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEG 292
++ EG +C G + D S C C G T C +G
Sbjct: 1137 KVNV-------EGIHCDRCRPGKFGLDAKNPLGCSSC-YCFGTTTQCSEAKG 1180
Score = 38.1 bits (87), Expect = 0.035
Identities = 52/253 (20%), Positives = 76/253 (30%), Gaps = 58/253 (22%)
Query: 348 QSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKE 407
++CP + C H C D C+ C G + AGT+ K
Sbjct: 294 RACPLDPATNKSRCECEHNTC-------GDSCDQCCP-------GFHQKPWRAGTFLTKT 339
Query: 408 TKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
E +CH C ++ L +N RG + C + C+ C
Sbjct: 340 ECEACNCHGKAEECYYDEN--VARRNLSLNIRGKYIGGGVCINCTQ-NTAGINCETCTDG 396
Query: 468 CFHCMGPAEDQ---CQTCPMNSL-LLNTTCVKD--------------------------C 497
F G + + CQ C + + LN CVKD C
Sbjct: 397 FFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRC 456
Query: 498 PEGYYADEDSNRCA----------HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCR 547
GY D C C C E C C+ G+F L ++ C
Sbjct: 457 ARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 548 EGYYADNSTGRCE 560
E + + RC+
Sbjct: 517 E-CFCSGVSNRCQ 528
Score = 36.6 bits (83), Expect = 0.10
Identities = 44/179 (24%), Positives = 63/179 (35%), Gaps = 45/179 (25%)
Query: 128 CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPC----HSS---- 179
C+ G C +C G LR +Q G+ L PC HSS
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLR--------SQPGGRTPGPTLGTCVPCQCNGHSSLCDP 1431
Query: 180 ----CKTC--NGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
C+ C + + C C G Y + + + C Q P + S + N + +C + G
Sbjct: 1432 ETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSN--NFSPSC-VAEG 1488
Query: 234 ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGN-ATNCHSCE 291
D + RC + CP G E CERC+ GN +C CE
Sbjct: 1489 LD----------------DYRC-TACPRG--YEGQYCERCAPGYTGSPGNPGGSCQECE 1528
Score = 35.4 bits (80), Expect = 0.23
Identities = 54/219 (24%), Positives = 74/219 (33%), Gaps = 72/219 (32%)
Query: 262 GSYAEDGICERCSSPCRTCEGNATNCHSCEG-----------GHVLHHGVCQ-------- 302
G++ CE C+ C G A C+ E G + GVC
Sbjct: 333 GTFLTKTECEACN-----CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 303 ---ENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMC---HQSCPRGFYA 356
E C + KGV + P CQ C C P L +++C + RG
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPC-------HCDPIGSL-NEVCVKDEKHARRGLAP 439
Query: 357 DSRHC------VPC---------HKDCLECS----GPKADD-----CELCLESSWVLYDG 392
S HC V C + DC C+ G K +D C +C E+ +G
Sbjct: 440 GSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPC-ICKEN----VEG 494
Query: 393 LCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQ 431
C +G + +E D K C C SG CQ
Sbjct: 495 GDCSRCKSGFFNLQE-----DNWKGCDECFCSGVSNRCQ 528
Score = 35.0 bits (79), Expect = 0.30
Identities = 61/261 (23%), Positives = 79/261 (30%), Gaps = 61/261 (23%)
Query: 60 CY---KTCPEKTYSEAVECKACDSNCG-SCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
CY + CP + C+ + CG SCDQ C PGF+
Sbjct: 289 CYGHARACPLDPATNKSRCECEHNTCGDSCDQ--------------------CCPGFHQK 328
Query: 116 QEMG-------ECESC--HRACETC---TGPGHDECSSCQEGLQLLRGMCVHATK----- 158
ECE+C H E C S G + G+C++ T+
Sbjct: 329 PWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGI 388
Query: 159 ---TQEEGKFWN-----DILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQ 210
T +G F + R QPCH C +C K A C
Sbjct: 389 NCETCTDGFFRPKGVSPNYPRPCQPCH--CDPIGSLNEVCVKDEKHARRGLAPGSCHCKT 446
Query: 211 GTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGIC 270
G SC+ C +G CK C +E C+ C E G C
Sbjct: 447 G----FGGVSCDRCARGY---TGYPDCKACNCSGLGSK--NEDPCFGPCICKENVEGGDC 497
Query: 271 ERCSSP-CRTCEGNATNCHSC 290
RC S E N C C
Sbjct: 498 SRCKSGFFNLQEDNWKGCDEC 518
Score = 34.3 bits (77), Expect = 0.50
Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 52/179 (29%)
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN------CLS 630
C +C F+ LRS+ P + TC C QC G +L C +
Sbjct: 1391 CEACLPGFYRLRSQPGGRTPGP-------TLGTCVPC-----QCNGHSSLCDPETSICQN 1438
Query: 631 CVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKC-----------HESCMECKGPGAKNC 679
C +H G C C +G Y + +G +C++C SC+ +G C
Sbjct: 1439 C--QHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCV-AEGLDDYRC 1494
Query: 680 TLCPANLVLHMDDSHCLHCC--NTSDP----PSAQEC-CD--------CQDTTDECILR 723
T CP + +C C T P S QEC CD C T C R
Sbjct: 1495 TACPRG----YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549
Score = 30.8 bits (68), Expect = 5.6
Identities = 62/280 (22%), Positives = 83/280 (29%), Gaps = 74/280 (26%)
Query: 268 GICERCSSPCRTCEGN-ATNCHSCEGGHVLHHGVCQENCPERH--------VAVKGVCK- 317
G+C C R C + ATN CE H C + CP H K C+
Sbjct: 285 GMCI-CYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 318 -HCPEMCQDCIHEK-------------------TCKECTPEFFLHDDMCHQSCPRGFYAD 357
+C ++C +++ C CT + ++C GF+
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQN---TAGINCETCTDGFFRP 400
Query: 358 S-------RHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKE 410
R C PCH D P E+C++ GL C
Sbjct: 401 KGVSPNYPRPCQPCHCD------PIGSLNEVCVKDEKHARRGLAPGSC------------ 442
Query: 411 CRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFH 470
C T +C C +G P C A CS +ED PC C
Sbjct: 443 ------HCKTGFGGVSCDRCARGYTGYP--DCKAC-NCSGLGSKNED-----PCFGPCIC 488
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRC 510
C C L K C E + SNRC
Sbjct: 489 KENVEGGDCSRCKSGFFNLQEDNWKGCDE-CFCSGVSNRC 527
Score = 30.4 bits (67), Expect = 7.3
Identities = 40/165 (24%), Positives = 52/165 (31%), Gaps = 47/165 (28%)
Query: 441 SCMANEKCSPSEYWDEDAPG----------CKPCHVKCFHCM-GPAEDQCQTCPMNSLLL 489
S ++ E C P Y PG C PC + P CQ C ++
Sbjct: 1387 SGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTA-- 1444
Query: 490 NTTCVKDCPEGYYA-----DEDSNRCA--------HCHSSCRTCEGRHSRQCHSCRPGWF 536
C + C GYY D +CA + SC EG +C +C G+
Sbjct: 1445 GDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC-VAEGLDDYRCTACPRGY- 1501
Query: 537 QLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
EG Y CERC G G C C+
Sbjct: 1502 -----------EGQY-------CERCAPGYTGSPGNPGGSCQECE 1528
>gi|29725609 epidermal growth factor receptor isoform a precursor
[Homo sapiens]
Length = 1210
Score = 65.1 bits (157), Expect = 3e-10
Identities = 119/502 (23%), Positives = 176/502 (35%), Gaps = 91/502 (18%)
Query: 118 MGECESCHRACE--TCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQP 175
+G C+ C +C +C G G + C +L + +C + GK +D
Sbjct: 184 LGSCQKCDPSCPNGSCWGAGEENCQ------KLTKIICAQQCSGRCRGKSPSDC------ 231
Query: 176 CHSSCKT-CNGSATL-CTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
CH+ C C G C C K + C +CP + + + E G
Sbjct: 232 CHNQCAAGCTGPRESDCLVCRK--FRDEATCKDTCPPLMLYNPTTYQMDVNPEG-KYSFG 288
Query: 234 ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYA--EDGI--CERCSSPCR-TCE----GNA 284
A KKC P + + G C C SY EDG+ C++C PCR C G
Sbjct: 289 ATCVKKC---PRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEF 345
Query: 285 TNCHSCEGGHVLHHGVCQENCPERH---VAVKG-VCKHCPEM-CQDCIHEKTCKECTPEF 339
+ S ++ H C + H VA +G H P + Q+ KT KE T
Sbjct: 346 KDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFL 405
Query: 340 FLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGL-CLEEC 398
+ Q+ P H + + + + L + S + GL L+E
Sbjct: 406 LI------QAWPEN--RTDLHAFE-NLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEI 456
Query: 399 PAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRG--SCMANEKCSPSEYWDE 456
G K C+ + + T+ QK I++ RG SC A +
Sbjct: 457 SDGDVIISGNKNL--CYANTINWKKL-FGTSGQKTKIISNRGENSCKATGQV-------- 505
Query: 457 DAPGCKPCHVKCF--HCMGPAEDQCQTCPMNSLLLNTTCVKDCP--EGYYAD-EDSNRCA 511
CH C C GP C +C ++ CV C EG + +++ C
Sbjct: 506 -------CHALCSPEGCWGPEPRDCVSC--RNVSRGRECVDKCNLLEGEPREFVENSECI 556
Query: 512 HCHSSCR------TCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST--------- 556
CH C TC GR C C + G C+ C G +N+T
Sbjct: 557 QCHPECLPQAMNITCTGRGPDNCIQC--AHYIDGPHCVKTCPAGVMGENNTLVWKYADAG 614
Query: 557 GRCERCNRSCK-GCQGPRPTDC 577
C C+ +C GC GP C
Sbjct: 615 HVCHLCHPNCTYGCTGPGLEGC 636
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/178 (28%), Positives = 74/178 (41%), Gaps = 37/178 (20%)
Query: 528 CHSCRPGWFQL----GKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRF 583
C++ W +L G++ + G + +TG+ S +GC GP P DC+SC
Sbjct: 470 CYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNV 529
Query: 584 FFLLRSKG-ECHRSC-----PDHYYVEQSTQTCERCHPTC------DQCKGKGALNCLSC 631
S+G EC C +VE S C +CHP C C G+G NC+ C
Sbjct: 530 -----SRGRECVDKCNLLEGEPREFVENS--ECIQCHPECLPQAMNITCTGRGPDNCIQC 582
Query: 632 VWSYHLMGGICTSDCLVGEYRVGEGEKF---------NCEKCHESC-MECKGPGAKNC 679
++++ G C C G +GE C CH +C C GPG + C
Sbjct: 583 --AHYIDGPHCVKTCPAGV--MGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 31/139 (22%)
Query: 513 CHSSCRT--CEGRHSRQCHSCRPGWFQLGKECLLQCR--EG---YYADNSTGRCERCNRS 565
CH+ C C G R C SCR G+EC+ +C EG + +NS C +C+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRN--VSRGRECVDKCNLLEGEPREFVENS--ECIQCHPE 561
Query: 566 CK------GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQST---------QTC 610
C C G P +C+ C + C ++CP E +T C
Sbjct: 562 CLPQAMNITCTGRGPDNCIQCAHYI----DGPHCVKTCPAGVMGENNTLVWKYADAGHVC 617
Query: 611 ERCHPTCDQ-CKGKGALNC 628
CHP C C G G C
Sbjct: 618 HLCHPNCTYGCTGPGLEGC 636
Score = 51.2 bits (121), Expect = 4e-06
Identities = 46/169 (27%), Positives = 66/169 (39%), Gaps = 27/169 (15%)
Query: 524 HSRQCHSCRPGW-----FQLGKECLLQCREGYYADNSTGRC------ERCNRSCK-GCQG 571
H C C P + G+E + + A +GRC + C+ C GC G
Sbjct: 183 HLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTG 242
Query: 572 PRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK---GALNC 628
PR +DCL C +F R + C +CP +T + +P +GK GA
Sbjct: 243 PRESDCLVCRKF----RDEATCKDTCPPLMLYNPTTYQMD-VNP-----EGKYSFGATCV 292
Query: 629 LSCVWSYHLMG-GICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPG 675
C +Y + G C C Y + E C+KC C + C G G
Sbjct: 293 KKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIG 341
Score = 38.9 bits (89), Expect = 0.020
Identities = 44/224 (19%), Positives = 67/224 (29%), Gaps = 74/224 (33%)
Query: 328 HEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESSW 387
H +C++C P SCP G C G ++C+ +
Sbjct: 183 HLGSCQKCDP-----------SCPNG----------------SCWGAGEENCQKLTKI-- 213
Query: 388 VLYDGLCLEECPAGTYYEKETKECRDCHKSCL---TCSSSGTCTTCQKGLIMNPRGSCMA 444
+C ++C +G K +C CH C T C C+K R
Sbjct: 214 -----ICAQQC-SGRCRGKSPSDC--CHNQCAAGCTGPRESDCLVCRKF-----RDEATC 260
Query: 445 NEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYAD 504
+ C P ++ P Q P TCVK CP Y
Sbjct: 261 KDTCPPLMLYN------------------PTTYQMDVNPEGKYSFGATCVKKCPRNYVVT 302
Query: 505 EDSNRCAHCHS-----------SCRTCEGRHSRQCHSCRPGWFQ 537
+ + C + C+ CEG + C+ G F+
Sbjct: 303 DHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFK 346
Score = 35.8 bits (81), Expect = 0.17
Identities = 39/137 (28%), Positives = 48/137 (35%), Gaps = 26/137 (18%)
Query: 75 CKACDSNCGS-CDQNGCYWCEEGFFLL------GGSCVRKCGPGFYGDQ----EMGECES 123
CKA C + C GC+ E + G CV KC G+ E EC
Sbjct: 499 CKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNL-LEGEPREFVENSECIQ 557
Query: 124 CHRACE------TCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW--NDILRKLQP 175
CH C TCTG G D C C + H KT G N ++ K
Sbjct: 558 CHPECLPQAMNITCTGRGPDNCIQCAHYID-----GPHCVKTCPAGVMGENNTLVWKYAD 612
Query: 176 CHSSCKTCNGSATL-CT 191
C C+ + T CT
Sbjct: 613 AGHVCHLCHPNCTYGCT 629
Score = 33.1 bits (74), Expect = 1.1
Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 18/78 (23%)
Query: 65 PEKTYSEAVEC-KACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG--EC 121
PE YS C K C N D GSCVR CG Y +E G +C
Sbjct: 281 PEGKYSFGATCVKKCPRNYVVTDH--------------GSCVRACGADSYEMEEDGVRKC 326
Query: 122 ESCHRAC-ETCTGPGHDE 138
+ C C + C G G E
Sbjct: 327 KKCEGPCRKVCNGIGIGE 344
>gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homolog
4 isoform JM-a/CVT-2 precursor [Homo sapiens]
Length = 1292
Score = 64.7 bits (156), Expect = 3e-10
Identities = 47/158 (29%), Positives = 65/158 (41%), Gaps = 29/158 (18%)
Query: 547 REGYYADNSTGRCERCNRSCK--GCQGPRPTDCLSCDRFFFLLRSKGE-CHRSC---PDH 600
R+ A+N T CN C GC GP P CLSC RF S+G C SC
Sbjct: 488 RDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRF-----SRGRICIESCNLYDGE 542
Query: 601 YYVEQSTQTCERCHPTCDQ-------CKGKGALNCLSCVWSYHLMGGICTSDCLVG---- 649
+ ++ C C P C++ C G G NC C S+ G C C G
Sbjct: 543 FREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGA 600
Query: 650 ---EYRVGEGEKFNCEKCHESCME-CKGPGAKNCTLCP 683
++ + ++ C CH +C + C GP + +C P
Sbjct: 601 NSFIFKYADPDR-ECHPCHPNCTQGCNGPTSHDCIYYP 637
Score = 56.2 bits (134), Expect = 1e-07
Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 43/226 (19%)
Query: 507 SNRCAHCHSSCR-TCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRS 565
S+ C CH SC C G C + ++C +C Y +D C C+R
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT--VCAEQCDGRCYGPYVSD-----C--CHRE 233
Query: 566 CKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
C G C GP+ TDC +C F G C CP + +T E + G
Sbjct: 234 CAGGCSGPKDTDCFACMNF----NDSGACVTQCPQTFVYNPTTFQLEH---NFNAKYTYG 286
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPGAK------ 677
A C ++ + C C + V E C+ C + C + C G G
Sbjct: 287 AFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQ 346
Query: 678 -----------NCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCD 712
NCT NL+ + H DP +A E D
Sbjct: 347 TVDSSNIDKFINCTKINGNLIFLVTGIH-------GDPYNAIEAID 385
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCP--EGYYAD-EDSNRCAHCHSSCR-------TC 520
C GP DQC +C S C++ C +G + + E+ + C C C TC
Sbjct: 512 CWGPGPDQCLSCRRFS--RGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTC 569
Query: 521 EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNS--------TGRCERCNRSC-KGCQG 571
G C C F+ G C+ +C +G NS C C+ +C +GC G
Sbjct: 570 HGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
Query: 572 PRPTDCL 578
P DC+
Sbjct: 628 PTSHDCI 634
Score = 48.5 bits (114), Expect = 3e-05
Identities = 43/175 (24%), Positives = 70/175 (40%), Gaps = 31/175 (17%)
Query: 358 SRHCVPCHKDCL-ECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHK 416
S C CHK C C GP + C+ + +C E+C G Y +C CH+
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT-------VCAEQCD-GRCYGPYVSDC--CHR 232
Query: 417 SCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC------SPSEYWDEDAPGCKPCHVKCFH 470
C S T C + N G+C+ +C +P+ + E K +
Sbjct: 233 ECAGGCSGPKDTDCFACMNFNDSGACVT--QCPQTFVYNPTTFQLEHNFNAK--YTYGAF 288
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDS--NRCAHCHSSC-RTCEG 522
C+ + CP N ++ +++CV+ CP E++ C C C + C+G
Sbjct: 289 CV-------KKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDG 336
Score = 47.0 bits (110), Expect = 8e-05
Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 16/111 (14%)
Query: 599 DHYYVEQSTQTCERCHPTC--DQCKGKGALNCLSCVWSYHLMGGICTSDCLV--GEYRVG 654
D+ E T C+ C D C G G CLSC G IC C + GE+R
Sbjct: 489 DNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSC--RRFSRGRICIESCNLYDGEFREF 546
Query: 655 EGEKF------NCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCC 699
E CEK + + C GPG NCT C D +C+ C
Sbjct: 547 ENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSH----FKDGPNCVEKC 593
Score = 44.7 bits (104), Expect = 4e-04
Identities = 37/150 (24%), Positives = 51/150 (34%), Gaps = 32/150 (21%)
Query: 303 ENCPERHVAVKGVCKH--C----PEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYA 356
ENC + +C C P+ C C + C L+D + +
Sbjct: 494 ENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFRE------FE 547
Query: 357 DSRHCVPCHKDC-------LECSGPKADDCELCLESSWVLYDGL-CLEECPAGTY----- 403
+ CV C C L C GP D+C C DG C+E+CP G
Sbjct: 548 NGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFK----DGPNCVEKCPDGLQGANSF 603
Query: 404 ---YEKETKECRDCHKSCLTCSSSGTCTTC 430
Y +EC CH +C + T C
Sbjct: 604 IFKYADPDRECHPCHPNCTQGCNGPTSHDC 633
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/229 (23%), Positives = 76/229 (33%), Gaps = 55/229 (24%)
Query: 166 WNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT 225
W DI+R P + + + NGS+ C C K SC W G EN
Sbjct: 163 WQDIVRNPWPSNLTLVSTNGSSG-CGRCHK-----------SCTGRCW-----GPTENHC 205
Query: 226 EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNAT 285
+ A+ C +GRCY G Y D C+ C + T
Sbjct: 206 QTLTRTVCAEQC--------------DGRCY-----GPYVSDCCHRECAGGCSGPKD--T 244
Query: 286 NCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDM 345
+C +C + G C CP+ V + P Q H K + +
Sbjct: 245 DCFACMNFN--DSGACVTQCPQTFV-------YNPTTFQ-LEHNFNAK------YTYGAF 288
Query: 346 CHQSCPRGFYADSRHCV-PCHKDCLECSGPKADDCELCLESSWVLYDGL 393
C + CP F DS CV C +E C+ C + DG+
Sbjct: 289 CVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGI 337
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 14/156 (8%)
Query: 316 CKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADS-RHCVPCHKDCLE-CSG 373
C C + C T C L +C + C Y C CH++C CSG
Sbjct: 186 CGRCHKSCTGRCWGPTENHCQT---LTRTVCAEQCDGRCYGPYVSDC--CHRECAGGCSG 240
Query: 374 PKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCT-TCQK 432
PK DC C+ + G C+ +CP Y T + H + C C
Sbjct: 241 PKDTDCFACMNFN---DSGACVTQCPQTFVYNPTTFQLE--HNFNAKYTYGAFCVKKCPH 295
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKC 468
+++ SC+ S E + CKPC C
Sbjct: 296 NFVVD-SSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/174 (23%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 554 NSTGRCERCNRSCKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCER 612
N + C RC++SC G C GP C + R + G C+ +
Sbjct: 181 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCY-----------GPYVSDC 229
Query: 613 CHPTC-DQCKGKGALNCLSCVWSYHLMGGICTSDC----LVGEYRVGEGEKFNCEKCHES 667
CH C C G +C +C+ G C + C + FN + +
Sbjct: 230 CHRECAGGCSGPKDTDCFACM--NFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTY-- 285
Query: 668 CMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCD-CQDTTDEC 720
GA CP N V +D S C+ C +S + C+ TD C
Sbjct: 286 -------GAFCVKKCPHNFV--VDSSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 20/137 (14%)
Query: 66 EKTYSEAVECK-ACDSN-CGSCDQNGCYWCEEGFFLLGGSCVRKCG--PGFYGDQEMGE- 120
E +E + C C S+ C + C C F G C+ C G + + E G
Sbjct: 494 ENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRR--FSRGRICIESCNLYDGEFREFENGSI 551
Query: 121 CESCHRACE-------TCTGPGHDECSSC---QEGLQLLRGMCVHATKTQEEGKF-WNDI 169
C C CE TC GPG D C+ C ++G + C + F + D
Sbjct: 552 CVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVE-KCPDGLQGANSFIFKYADP 610
Query: 170 LRKLQPCHSSC-KTCNG 185
R+ PCH +C + CNG
Sbjct: 611 DRECHPCHPNCTQGCNG 627
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/168 (23%), Positives = 51/168 (30%), Gaps = 56/168 (33%)
Query: 371 CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTC 430
C GP D C C S +C+E C Y+ E +E + C C
Sbjct: 512 CWGPGPDQCLSCRRFS---RGRICIESC---NLYDGEFREFEN----------GSICVEC 555
Query: 431 QKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLN 490
P C+ C GP D C C +
Sbjct: 556 D---------------------------PQCEKMEDGLLTCHGPGPDNCTKC--SHFKDG 586
Query: 491 TTCVKDCPEGY---------YADEDSNRCAHCHSSC-RTCEGRHSRQC 528
CV+ CP+G YAD D C CH +C + C G S C
Sbjct: 587 PNCVEKCPDGLQGANSFIFKYADPD-RECHPCHPNCTQGCNGPTSHDC 633
Score = 40.0 bits (92), Expect = 0.009
Identities = 43/174 (24%), Positives = 58/174 (33%), Gaps = 54/174 (31%)
Query: 124 CHRACET--CTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCK 181
C+ C + C GPG D+C SC+ + RG + +G+F R+ +
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCR---RFSRGRICIESCNLYDGEF-----REFE------- 547
Query: 182 TCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGA--DLCKK 239
NGS CV PQ CE + C G D C K
Sbjct: 548 --NGSI----------------CVECDPQ----------CEKMEDGLLTCHGPGPDNCTK 579
Query: 240 CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNC-HSCEG 292
C P C KCP+G + + + P R C NC C G
Sbjct: 580 CSHFKDGP------NCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
>gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-1 precursor [Homo sapiens]
Length = 1308
Score = 64.7 bits (156), Expect = 3e-10
Identities = 47/158 (29%), Positives = 65/158 (41%), Gaps = 29/158 (18%)
Query: 547 REGYYADNSTGRCERCNRSCK--GCQGPRPTDCLSCDRFFFLLRSKGE-CHRSC---PDH 600
R+ A+N T CN C GC GP P CLSC RF S+G C SC
Sbjct: 488 RDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRF-----SRGRICIESCNLYDGE 542
Query: 601 YYVEQSTQTCERCHPTCDQ-------CKGKGALNCLSCVWSYHLMGGICTSDCLVG---- 649
+ ++ C C P C++ C G G NC C S+ G C C G
Sbjct: 543 FREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGA 600
Query: 650 ---EYRVGEGEKFNCEKCHESCME-CKGPGAKNCTLCP 683
++ + ++ C CH +C + C GP + +C P
Sbjct: 601 NSFIFKYADPDR-ECHPCHPNCTQGCNGPTSHDCIYYP 637
Score = 56.2 bits (134), Expect = 1e-07
Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 43/226 (19%)
Query: 507 SNRCAHCHSSCR-TCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRS 565
S+ C CH SC C G C + ++C +C Y +D C C+R
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT--VCAEQCDGRCYGPYVSD-----C--CHRE 233
Query: 566 CKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
C G C GP+ TDC +C F G C CP + +T E + G
Sbjct: 234 CAGGCSGPKDTDCFACMNF----NDSGACVTQCPQTFVYNPTTFQLEH---NFNAKYTYG 286
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPGAK------ 677
A C ++ + C C + V E C+ C + C + C G G
Sbjct: 287 AFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQ 346
Query: 678 -----------NCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCD 712
NCT NL+ + H DP +A E D
Sbjct: 347 TVDSSNIDKFINCTKINGNLIFLVTGIH-------GDPYNAIEAID 385
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCP--EGYYAD-EDSNRCAHCHSSCR-------TC 520
C GP DQC +C S C++ C +G + + E+ + C C C TC
Sbjct: 512 CWGPGPDQCLSCRRFS--RGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTC 569
Query: 521 EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNS--------TGRCERCNRSC-KGCQG 571
G C C F+ G C+ +C +G NS C C+ +C +GC G
Sbjct: 570 HGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
Query: 572 PRPTDCL 578
P DC+
Sbjct: 628 PTSHDCI 634
Score = 48.5 bits (114), Expect = 3e-05
Identities = 43/175 (24%), Positives = 70/175 (40%), Gaps = 31/175 (17%)
Query: 358 SRHCVPCHKDCL-ECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHK 416
S C CHK C C GP + C+ + +C E+C G Y +C CH+
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT-------VCAEQCD-GRCYGPYVSDC--CHR 232
Query: 417 SCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC------SPSEYWDEDAPGCKPCHVKCFH 470
C S T C + N G+C+ +C +P+ + E K +
Sbjct: 233 ECAGGCSGPKDTDCFACMNFNDSGACVT--QCPQTFVYNPTTFQLEHNFNAK--YTYGAF 288
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDS--NRCAHCHSSC-RTCEG 522
C+ + CP N ++ +++CV+ CP E++ C C C + C+G
Sbjct: 289 CV-------KKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDG 336
Score = 47.0 bits (110), Expect = 8e-05
Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 16/111 (14%)
Query: 599 DHYYVEQSTQTCERCHPTC--DQCKGKGALNCLSCVWSYHLMGGICTSDCLV--GEYRVG 654
D+ E T C+ C D C G G CLSC G IC C + GE+R
Sbjct: 489 DNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSC--RRFSRGRICIESCNLYDGEFREF 546
Query: 655 EGEKF------NCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCC 699
E CEK + + C GPG NCT C D +C+ C
Sbjct: 547 ENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSH----FKDGPNCVEKC 593
Score = 44.7 bits (104), Expect = 4e-04
Identities = 37/150 (24%), Positives = 51/150 (34%), Gaps = 32/150 (21%)
Query: 303 ENCPERHVAVKGVCKH--C----PEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYA 356
ENC + +C C P+ C C + C L+D + +
Sbjct: 494 ENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFRE------FE 547
Query: 357 DSRHCVPCHKDC-------LECSGPKADDCELCLESSWVLYDGL-CLEECPAGTY----- 403
+ CV C C L C GP D+C C DG C+E+CP G
Sbjct: 548 NGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFK----DGPNCVEKCPDGLQGANSF 603
Query: 404 ---YEKETKECRDCHKSCLTCSSSGTCTTC 430
Y +EC CH +C + T C
Sbjct: 604 IFKYADPDRECHPCHPNCTQGCNGPTSHDC 633
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/229 (23%), Positives = 76/229 (33%), Gaps = 55/229 (24%)
Query: 166 WNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT 225
W DI+R P + + + NGS+ C C K SC W G EN
Sbjct: 163 WQDIVRNPWPSNLTLVSTNGSSG-CGRCHK-----------SCTGRCW-----GPTENHC 205
Query: 226 EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNAT 285
+ A+ C +GRCY G Y D C+ C + T
Sbjct: 206 QTLTRTVCAEQC--------------DGRCY-----GPYVSDCCHRECAGGCSGPKD--T 244
Query: 286 NCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDM 345
+C +C + G C CP+ V + P Q H K + +
Sbjct: 245 DCFACMNFN--DSGACVTQCPQTFV-------YNPTTFQ-LEHNFNAK------YTYGAF 288
Query: 346 CHQSCPRGFYADSRHCV-PCHKDCLECSGPKADDCELCLESSWVLYDGL 393
C + CP F DS CV C +E C+ C + DG+
Sbjct: 289 CVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGI 337
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 14/156 (8%)
Query: 316 CKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADS-RHCVPCHKDCLE-CSG 373
C C + C T C L +C + C Y C CH++C CSG
Sbjct: 186 CGRCHKSCTGRCWGPTENHCQT---LTRTVCAEQCDGRCYGPYVSDC--CHRECAGGCSG 240
Query: 374 PKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCT-TCQK 432
PK DC C+ + G C+ +CP Y T + H + C C
Sbjct: 241 PKDTDCFACMNFN---DSGACVTQCPQTFVYNPTTFQLE--HNFNAKYTYGAFCVKKCPH 295
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKC 468
+++ SC+ S E + CKPC C
Sbjct: 296 NFVVD-SSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/174 (23%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 554 NSTGRCERCNRSCKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCER 612
N + C RC++SC G C GP C + R + G C+ +
Sbjct: 181 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCY-----------GPYVSDC 229
Query: 613 CHPTC-DQCKGKGALNCLSCVWSYHLMGGICTSDC----LVGEYRVGEGEKFNCEKCHES 667
CH C C G +C +C+ G C + C + FN + +
Sbjct: 230 CHRECAGGCSGPKDTDCFACM--NFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTY-- 285
Query: 668 CMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCD-CQDTTDEC 720
GA CP N V +D S C+ C +S + C+ TD C
Sbjct: 286 -------GAFCVKKCPHNFV--VDSSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 20/137 (14%)
Query: 66 EKTYSEAVECK-ACDSN-CGSCDQNGCYWCEEGFFLLGGSCVRKCG--PGFYGDQEMGE- 120
E +E + C C S+ C + C C F G C+ C G + + E G
Sbjct: 494 ENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRR--FSRGRICIESCNLYDGEFREFENGSI 551
Query: 121 CESCHRACE-------TCTGPGHDECSSC---QEGLQLLRGMCVHATKTQEEGKF-WNDI 169
C C CE TC GPG D C+ C ++G + C + F + D
Sbjct: 552 CVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVE-KCPDGLQGANSFIFKYADP 610
Query: 170 LRKLQPCHSSC-KTCNG 185
R+ PCH +C + CNG
Sbjct: 611 DRECHPCHPNCTQGCNG 627
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/168 (23%), Positives = 51/168 (30%), Gaps = 56/168 (33%)
Query: 371 CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTC 430
C GP D C C S +C+E C Y+ E +E + C C
Sbjct: 512 CWGPGPDQCLSCRRFS---RGRICIESC---NLYDGEFREFEN----------GSICVEC 555
Query: 431 QKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLN 490
P C+ C GP D C C +
Sbjct: 556 D---------------------------PQCEKMEDGLLTCHGPGPDNCTKC--SHFKDG 586
Query: 491 TTCVKDCPEGY---------YADEDSNRCAHCHSSC-RTCEGRHSRQC 528
CV+ CP+G YAD D C CH +C + C G S C
Sbjct: 587 PNCVEKCPDGLQGANSFIFKYADPD-RECHPCHPNCTQGCNGPTSHDC 633
Score = 40.0 bits (92), Expect = 0.009
Identities = 43/174 (24%), Positives = 58/174 (33%), Gaps = 54/174 (31%)
Query: 124 CHRACET--CTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCK 181
C+ C + C GPG D+C SC+ + RG + +G+F R+ +
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCR---RFSRGRICIESCNLYDGEF-----REFE------- 547
Query: 182 TCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGA--DLCKK 239
NGS CV PQ CE + C G D C K
Sbjct: 548 --NGSI----------------CVECDPQ----------CEKMEDGLLTCHGPGPDNCTK 579
Query: 240 CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNC-HSCEG 292
C P C KCP+G + + + P R C NC C G
Sbjct: 580 CSHFKDGP------NCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 63.2 bits (152), Expect = 1e-09
Identities = 111/485 (22%), Positives = 165/485 (34%), Gaps = 135/485 (27%)
Query: 273 CSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTC 332
C C T G+A C G ++ GV E+ E C DC + C
Sbjct: 689 CKQVCSTVGGSAI-CSCFPGYAIMADGVSCEDQDE-----------CLMGAHDCSRRQFC 736
Query: 333 KECTPEFFLHDDMCHQSCPRGFYADS-RHCVP---CHKDCLECSGPKADDC--------- 379
F+ + C G+ ++ R CV C D CS + + C
Sbjct: 737 VNTLGSFYCVNHTV--LCADGYILNAHRKCVDINECVTDLHTCS--RGEHCVNTLGSFHC 792
Query: 380 --ELCLESSWVLYDGLC--LEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLI 435
L E + L DG C ++EC GT+ + C++ K C + C G +
Sbjct: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNT-KGSFYCQAR---QRCMDGFL 848
Query: 436 MNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVK 495
+P G+C+ +C+ + C+P C + +G TC N L+
Sbjct: 849 QDPEGNCVDINECTSL------SEPCRP-GFSCINTVG-----SYTCQRNPLI------- 889
Query: 496 DCPEGYYADEDSNRCA---HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYA 552
C GY+A +D +C C + C + CH+ PG ++ C+ G+
Sbjct: 890 -CARGYHASDDGTKCVDVNECETGVHRC--GEGQVCHNL-PGSYR------CDCKAGFQR 939
Query: 553 DNSTGRC-----------ERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGE--------- 592
D C C +C+ G C S FLL + G+
Sbjct: 940 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCAS----GFLLAADGKRCEDVNECE 995
Query: 593 ---CHRSCPDHY-----YVEQSTQTCERCHPTC---DQC-KGKGAL---NCLSCVWSYHL 637
C + C + Y Y Q Q E H TC D+C +G G L CL+ SY
Sbjct: 996 AQRCSQECANIYGSYQCYCRQGYQLAEDGH-TCTDIDECAQGAGILCTFRCLNVPGSYQC 1054
Query: 638 M-----------GGIC--TSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTL--C 682
G C +C +G + E E CH G+ C C
Sbjct: 1055 ACPEQGYTMTANGRSCKDVDECALGTHNCSE-----AETCHNI------QGSFRCLRFEC 1103
Query: 683 PANLV 687
P N V
Sbjct: 1104 PPNYV 1108
Score = 60.1 bits (144), Expect = 9e-09
Identities = 117/510 (22%), Positives = 178/510 (34%), Gaps = 94/510 (18%)
Query: 84 SCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQ 143
+C NG C++ +GGS + C PG+ M + SC E G HD CS Q
Sbjct: 682 TCKDNGP--CKQVCSTVGGSAICSCFPGY---AIMADGVSCEDQDECLMG-AHD-CSRRQ 734
Query: 144 EGLQLLRGM-CVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQ 202
+ L CV+ T +G N H C N T +C +G + +
Sbjct: 735 FCVNTLGSFYCVNHTVLCADGYILN--------AHRKCVDINECVTDLHTCSRGEHCVNT 786
Query: 203 A----CVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---CQMQPGHPLFLHEGRC 255
C + +++ G CE+ E CA+ G C+ CQ G RC
Sbjct: 787 LGSFHCYKALTCEPGYALKDGECEDVDE-CAM--GTHTCQPGFLCQNTKGSFYCQARQRC 843
Query: 256 ---YSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAV 312
+ + PEG+ + C S PCR +C + G + CQ N +
Sbjct: 844 MDGFLQDPEGNCVDINECTSLSEPCRP----GFSCINTVGSY-----TCQRN---PLICA 891
Query: 313 KGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQ-------SCPRGFYADS--RHCVP 363
+G H + C+ C E +CH C GF D+ R C+
Sbjct: 892 RGY--HASDDGTKCVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI- 947
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRD--------CH 415
D EC C+ E++ Y C C +G + K C D C
Sbjct: 948 ---DVNECWASPGRLCQHTCENTLGSY--RC--SCASGFLLAADGKRCEDVNECEAQRCS 1000
Query: 416 KSCLTCSSSGTCTTCQKGLIMNPRG-SCMANEKCSPSEYWDEDAPGCKPCHVKC-FHCMG 473
+ C S C C++G + G +C ++C+ + + C F C+
Sbjct: 1001 QECANIYGSYQC-YCRQGYQLAEDGHTCTDIDECA------------QGAGILCTFRCLN 1047
Query: 474 -PAEDQCQTCPMN--SLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHS 530
P QC CP ++ N KD E + + CH+ +G
Sbjct: 1048 VPGSYQC-ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHN----IQGSFRCLRFE 1102
Query: 531 CRPGWFQLGK-EC-LLQCREGYYADNSTGR 558
C P + Q+ K +C C + NS R
Sbjct: 1103 CPPNYVQVSKTKCERTTCHDFLECQNSPAR 1132
Score = 37.4 bits (85), Expect = 0.059
Identities = 62/291 (21%), Positives = 94/291 (32%), Gaps = 64/291 (21%)
Query: 411 CRD---CHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
C+D C + C T S C+ IM SC ++C + C +
Sbjct: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNT-LG 741
Query: 468 CFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQ 527
F+C+ + C + +LN + C + D + C+ T H +
Sbjct: 742 SFYCV----NHTVLC-ADGYILNAH--RKCVDINECVTDLHTCSRGEHCVNTLGSFHCYK 794
Query: 528 CHSCRPGWFQLGKEC---------LLQCREGYYADNSTGR--CERCNRSCKGCQGPRPTD 576
+C PG+ EC C+ G+ N+ G C+ R G
Sbjct: 795 ALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG-------- 846
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNC----LSCV 632
FL +G C + + T E C P G+ C L C
Sbjct: 847 --------FLQDPEGNC-------VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICA 891
Query: 633 WSYHLM--GGIC--TSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNC 679
YH G C ++C G +R GEG + CH PG+ C
Sbjct: 892 RGYHASDDGTKCVDVNECETGVHRCGEG-----QVCHNL------PGSYRC 931
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 62.8 bits (151), Expect = 1e-09
Identities = 95/446 (21%), Positives = 133/446 (29%), Gaps = 126/446 (28%)
Query: 102 GSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQE 161
G C PG+ + G + +C CT H C G+CV + T+
Sbjct: 681 GQFCESCAPGYKREMPQG---GPYASCVPCTCNQHGTCDPNT-------GICVCSHHTEG 730
Query: 162 EGKFWNDILRKLQPCHSSCKTC---------NGSATLCTSCPKGAYLLAQACVSSCPQGT 212
SC+ C G A C CP C T
Sbjct: 731 P----------------SCERCLPGFYGNPFAGQADDCQPCP---------CPGQSACTT 765
Query: 213 WPSVRSGSCENCTEA-----CAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAED 267
P R C +C C +C + GHP H+ +C +
Sbjct: 766 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLF-GHPQPCHQCQCSGNVDPNAV--- 821
Query: 268 GICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPE-MCQDC 326
G C+ S C C N T H C+HC E
Sbjct: 822 GNCDPLSGHCLRCLHNTTGDH---------------------------CEHCQEGFYGSA 854
Query: 327 IHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRHCVPCHKDCLECSGPKADDCELCLESS 386
+ + +C P CH P+G ++ C P C A DC C
Sbjct: 855 LAPRPADKCMP------CSCH---PQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
Query: 387 WVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANE 446
+ L G C +E + CH +G CT C+ G+ C
Sbjct: 906 FDLQPGRGCRSCKCHPLGSQEDQ----CHPK------TGQCT-CRPGVTGQACDRCQLG- 953
Query: 447 KCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADED 506
++ GC+ C +G A QC N TCV C G+ +
Sbjct: 954 ------FFGFSIKGCRACRCSP---LGAASAQCHE--------NGTCV--CRPGF----E 990
Query: 507 SNRCAHCHSSC-RTCEGRHSRQCHSC 531
+C CH + T +G H +QC SC
Sbjct: 991 GYKCDRCHDNFFLTADGTHCQQCPSC 1016
Score = 62.8 bits (151), Expect = 1e-09
Identities = 86/353 (24%), Positives = 115/353 (32%), Gaps = 109/353 (30%)
Query: 69 YSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRAC 128
Y+ V C C+ + G+CD N C G SC R C PGFYG+ G+ + C
Sbjct: 701 YASCVPC-TCNQH-GTCDPNTGI-CVCSHHTEGPSCER-CLPGFYGNPFAGQADD----C 752
Query: 129 ETCTGPGHDECSSCQEGLQLLRGMCVHATKTQE-------EGKFWNDILRKL---QPCH- 177
+ C PG C++ E ++ +C H Q + F+ D L QPCH
Sbjct: 753 QPCPCPGQSACTTIPESREV---VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQ 809
Query: 178 -------------------SSCKTC--NGSATLCTSCPKGAY--LLAQACVSSC------ 208
C C N + C C +G Y LA C
Sbjct: 810 CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCH 869
Query: 209 PQGT----------------WPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE 252
PQG+ P V + C C C+ C+ HPL E
Sbjct: 870 PQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKC---HPLGSQE 926
Query: 253 GRCYSK-----CPEGSYAEDGICERCS--------SPCRTCEGNATNCHSCEGGHVLHHG 299
+C+ K C G + C+RC CR C + S +
Sbjct: 927 DQCHPKTGQCTCRPGVTGQ--ACDRCQLGFFGFSIKGCRACRCSPLGAASAQ-------- 976
Query: 300 VCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCH-QSCP 351
C EN G C +C+ C C FFL D H Q CP
Sbjct: 977 -CHEN---------GTC-----VCRPGFEGYKCDRCHDNFFLTADGTHCQQCP 1014
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/377 (23%), Positives = 126/377 (33%), Gaps = 80/377 (21%)
Query: 374 PKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCL--TCSSSGTCTTCQ 431
P A E+C S Y G E C G Y++E + + SC+ TC+ GTC
Sbjct: 665 PPASWVEIC--SCPTGYTGQFCESCAPG--YKREMPQGGP-YASCVPCTCNQHGTCDPNT 719
Query: 432 KGLIMNPRGSCMANEKCSPSEYWDE---DAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLL 488
+ + + E+C P Y + A C+PC P + C T P + +
Sbjct: 720 GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC-------PGQSACTTIPESREV 772
Query: 489 LNTTC--------VKDCPEGYYADE-----DSNRCAHCHSS----------CRTCEGRHS 525
+ T C + C +G++ D C C S C G
Sbjct: 773 VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCL 832
Query: 526 RQCHSCRPGWFQLGKECLLQCREGYY----ADNSTGRCERCNRSCKGCQG---------- 571
R H+ G C C+EG+Y A +C C+ +G
Sbjct: 833 RCLHNTT------GDHCE-HCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 885
Query: 572 -----PRPT--DCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
P T DC C FF L+ C RSC H Q Q CHP QC +
Sbjct: 886 QCSCLPHVTARDCSRCYPGFFDLQPGRGC-RSCKCHPLGSQEDQ----CHPKTGQCTCRP 940
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYR-VGEGEKFNCEKCHES--CMECKGPGAKNCTL 681
+ +C G C +G +CHE+ C+ G C
Sbjct: 941 GVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASA----QCHENGTCVCRPGFEGYKCDR 996
Query: 682 CPANLVLHMDDSHCLHC 698
C N L D +HC C
Sbjct: 997 CHDNFFLTADGTHCQQC 1013
Score = 40.8 bits (94), Expect = 0.005
Identities = 59/259 (22%), Positives = 81/259 (31%), Gaps = 69/259 (26%)
Query: 292 GGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCP 351
GG +G E P+ VA + C+ CQ C+ C P F D +
Sbjct: 268 GGRCKCNGHASECGPD--VAGQLACR-----CQHNTTGTDCERCLP--FFQD----RPWA 314
Query: 352 RGFYADSRHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKEC 411
RG + C+PC+ CSG EEC + T
Sbjct: 315 RGTAEAAHECLPCN-----CSGRS--------------------EECTFDRELFRSTGHG 349
Query: 412 RDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC 471
CH C ++ C CQ+ +WD P C+PC +
Sbjct: 350 GRCHH-CRDHTAGPHCERCQENFY-----------------HWDPRMP-CQPCDCQSAGS 390
Query: 472 MGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH--SSCRTCEGRHSR--- 526
+ D TC + C + P + E R C+ S TC+ R R
Sbjct: 391 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPC 450
Query: 527 -------QCHSCRPGWFQL 538
C CRPG F L
Sbjct: 451 KENVEGNLCDRCRPGTFNL 469
Score = 37.4 bits (85), Expect = 0.059
Identities = 57/234 (24%), Positives = 74/234 (31%), Gaps = 42/234 (17%)
Query: 74 ECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM--GECESCHRACETC 131
+C S CG D G C G C R C P F+ D+ G E+ H C C
Sbjct: 272 KCNGHASECGP-DVAGQLACRCQHNTTGTDCER-CLP-FFQDRPWARGTAEAAHE-CLPC 327
Query: 132 TGPGHDECSSCQEGLQLLR-----GMC---------VHATKTQEEGKFWNDILRKLQPCH 177
G E C +L R G C H + QE W D QPC
Sbjct: 328 NCSGRSE--ECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW-DPRMPCQPCD 384
Query: 178 SSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLC 237
C + +L C + P+V C+ C S C
Sbjct: 385 -----CQSAGSLHLQCDDTGTCACK-----------PTVTGWKCDRCLPGFHSLSEGG-C 427
Query: 238 KKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCE-GNATNCHSC 290
+ C P L + R +CP E +C+RC + N C SC
Sbjct: 428 RPCTCNPAGSLDTCDPRS-GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC 480
Score = 31.6 bits (70), Expect = 3.3
Identities = 50/201 (24%), Positives = 64/201 (31%), Gaps = 22/201 (10%)
Query: 457 DAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHC--H 514
D C P G AE + P N + C D E + + RC HC H
Sbjct: 300 DCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFD-RELFRSTGHGGRCHHCRDH 358
Query: 515 SSCRTCEGRHSRQCH-----SCRPGWFQLGKECLLQCRE-GYYADNSTGRCERCNRSCKG 568
++ CE H C+P Q LQC + G A T +C+R G
Sbjct: 359 TAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPG 418
Query: 569 CQ-----GPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK 623
G RP C G C P VE + C+RC P +
Sbjct: 419 FHSLSEGGCRPCTCNPAGSLDTCDPRSGRC----PCKENVEGNL--CDRCRPGTFNLQPH 472
Query: 624 GALNCLSCVWSYHLMGGICTS 644
C SC H +C S
Sbjct: 473 NPAGCSSCFCYGH--SKVCAS 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.479
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,640,084
Number of Sequences: 37866
Number of extensions: 2576045
Number of successful extensions: 10593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 6978
Number of HSP's gapped (non-prelim): 2092
length of query: 853
length of database: 18,247,518
effective HSP length: 111
effective length of query: 742
effective length of database: 14,044,392
effective search space: 10420938864
effective search space used: 10420938864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.