BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|117938318 vacuolar protein sorting 37D [Homo sapiens] (251 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|117938318 vacuolar protein sorting 37D [Homo sapiens] 503 e-143 gi|57863314 vacuolar protein sorting 37C [Homo sapiens] 131 5e-31 gi|13375926 vacuolar protein sorting 37B [Homo sapiens] 127 9e-30 gi|223555921 hepatocellular carcinoma related protein 1 isoform ... 74 1e-13 gi|223555919 hepatocellular carcinoma related protein 1 isoform ... 74 1e-13 gi|47132519 Ras association and pleckstrin homology domains 1 is... 46 4e-05 gi|33356148 formin-like 1 [Homo sapiens] 46 4e-05 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 1e-04 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 1e-04 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 44 1e-04 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 44 1e-04 gi|8922157 proline rich 13 isoform 1 [Homo sapiens] 44 1e-04 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 44 2e-04 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 44 2e-04 gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 43 3e-04 gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 43 3e-04 gi|41281612 zinc finger protein 828 [Homo sapiens] 43 3e-04 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 4e-04 gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 42 5e-04 gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 42 5e-04 gi|9945318 MAX binding protein [Homo sapiens] 42 5e-04 gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 42 5e-04 gi|163965366 nascent polypeptide-associated complex alpha subuni... 42 7e-04 gi|157168329 formin 1 [Homo sapiens] 41 9e-04 gi|18079216 CASK interacting protein 1 [Homo sapiens] 41 9e-04 gi|40353727 synaptopodin isoform A [Homo sapiens] 41 9e-04 gi|34577114 cytomatrix protein p110 [Homo sapiens] 41 9e-04 gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase... 41 9e-04 gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 41 9e-04 gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 41 9e-04 >gi|117938318 vacuolar protein sorting 37D [Homo sapiens] Length = 251 Score = 503 bits (1296), Expect = e-143 Identities = 251/251 (100%), Positives = 251/251 (100%) Query: 1 MYRARAARAGPEPGSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLAS 60 MYRARAARAGPEPGSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLAS Sbjct: 1 MYRARAARAGPEPGSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLAS 60 Query: 61 NYALAKENLALRPRLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQ 120 NYALAKENLALRPRLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQ Sbjct: 61 NYALAKENLALRPRLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQ 120 Query: 121 AELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQ 180 AELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQ Sbjct: 121 AELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQ 180 Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS Sbjct: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 Query: 241 PRPSQPEPPHR 251 PRPSQPEPPHR Sbjct: 241 PRPSQPEPPHR 251 >gi|57863314 vacuolar protein sorting 37C [Homo sapiens] Length = 355 Score = 131 bits (330), Expect = 5e-31 Identities = 88/229 (38%), Positives = 122/229 (53%), Gaps = 13/229 (5%) Query: 26 QLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAIK 85 +L +L D +D++ S + Q LQLERE LA+N +LA+ NL + LE+ R+ L+ + Sbjct: 11 ELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDR 70 Query: 86 YQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSLE 145 YQELR++ E C ++ +LE+ P L LQ E + E+E+E E+ L GE LE Sbjct: 71 YQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLE 130 Query: 146 AFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAAR 205 FL F R L+HLRR + EKLQE++R+ S + A A PP+ P +P G Sbjct: 131 TFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELA--GDAPPPRPPPPVRPVPQGT-- 186 Query: 206 GPPAV-PRSLPPLDSRPVP-PLKGSPGCPLGPA------PLLSPRPSQP 246 PP V + PPL P P P SP P+GP P P SQP Sbjct: 187 -PPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQP 234 Score = 33.5 bits (75), Expect = 0.18 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 9/77 (11%) Query: 181 PAPTSAADPPK--------SFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGS-PGC 231 PAP P ++PAA + P GAA + RS+PP P P+ S PG Sbjct: 225 PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGY 284 Query: 232 PLGPAPLLSPRPSQPEP 248 PL SP Q P Sbjct: 285 PLRGGRAPSPGYPQQSP 301 Score = 31.2 bits (69), Expect = 0.89 Identities = 18/62 (29%), Positives = 24/62 (38%), Gaps = 1/62 (1%) Query: 189 PPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS-PRPSQPE 247 P +P + P + P + LP +P P + P P GPAP P P P Sbjct: 292 PSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPA 351 Query: 248 PP 249 P Sbjct: 352 WP 353 Score = 29.3 bits (64), Expect = 3.4 Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 5/80 (6%) Query: 176 ERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRS-LPPLDSRPV----PPLKGSPG 230 +RS P P P + L G A P +S P +P P L PG Sbjct: 263 QRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPG 322 Query: 231 CPLGPAPLLSPRPSQPEPPH 250 P PL P P P PP+ Sbjct: 323 QPQPSVPLQPPYPPGPAPPY 342 >gi|13375926 vacuolar protein sorting 37B [Homo sapiens] Length = 285 Score = 127 bits (319), Expect = 9e-30 Identities = 84/214 (39%), Positives = 119/214 (55%), Gaps = 6/214 (2%) Query: 14 GSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRP 73 GS RF LS QL +LL+DE +L +V+ + Q +QL +E LASN +LA+ NL +P Sbjct: 5 GSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQP 64 Query: 74 RLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQ 133 +L+ +A L KYQEL+ + E K +L+ S L LQAE + E++ E Sbjct: 65 QLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENM 124 Query: 134 MEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQP-APTSAADPPKS 192 E+ L GE L++F+ +Q R LAH+RR + EKLQE++ + +R Q AP P + Sbjct: 125 AEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELA 184 Query: 193 FPAAAVLPTGAARGPPAV-PRSLPPLDSRPVPPL 225 A P A GPPAV PR +PP P PP+ Sbjct: 185 PTAPLPYPAPEASGPPAVAPRRIPP----PPPPV 214 >gi|223555921 hepatocellular carcinoma related protein 1 isoform 2 [Homo sapiens] Length = 372 Score = 73.9 bits (180), Expect = 1e-13 Identities = 53/165 (32%), Positives = 83/165 (50%), Gaps = 10/165 (6%) Query: 22 LSTGQLRDLL-QDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRA 80 LS QL D+ Q+E L++ + L + Q + +++ + S LA++NL L P LE R Sbjct: 212 LSVSQLTDMNEQEEVLLEQFLTLPQLKQ-IITDKDDLVKSIEELARKNLLLEPSLEAKRQ 270 Query: 81 ALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQM----EQ 136 + KY+ L ++ K+QR H S C+ LQA L+ A EAEE+ E Sbjct: 271 TVLDKYELLTQMKSTFEKKMQR----QHELSESCSASALQARLKVAAHEAEEESDNIAED 326 Query: 137 LLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQP 181 L G+ ++ FL +F R + H RR + EKLQ+ + + P Sbjct: 327 FLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAP 371 >gi|223555919 hepatocellular carcinoma related protein 1 isoform 1 [Homo sapiens] Length = 397 Score = 73.9 bits (180), Expect = 1e-13 Identities = 53/165 (32%), Positives = 83/165 (50%), Gaps = 10/165 (6%) Query: 22 LSTGQLRDLL-QDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRA 80 LS QL D+ Q+E L++ + L + Q + +++ + S LA++NL L P LE R Sbjct: 237 LSVSQLTDMNEQEEVLLEQFLTLPQLKQ-IITDKDDLVKSIEELARKNLLLEPSLEAKRQ 295 Query: 81 ALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQM----EQ 136 + KY+ L ++ K+QR H S C+ LQA L+ A EAEE+ E Sbjct: 296 TVLDKYELLTQMKSTFEKKMQR----QHELSESCSASALQARLKVAAHEAEEESDNIAED 351 Query: 137 LLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQP 181 L G+ ++ FL +F R + H RR + EKLQ+ + + P Sbjct: 352 FLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAP 396 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 45.8 bits (107), Expect = 4e-05 Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Query: 181 PAPTSAADPPKSFPAAAVL---PTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAP 237 P P A PP++ P V PT P V ++ PP + PVPP K P P P Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825 Query: 238 LLSPRPSQPEPP 249 P P P PP Sbjct: 826 PSPPTPPVPVPP 837 Score = 35.8 bits (81), Expect = 0.036 Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 177 RSAQPAPTSAADPPK---SFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPL 233 ++A P PT P K +FPA+ + P+ P P +LP S P P PL Sbjct: 800 QAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP----PPSPL 855 Query: 234 GPAP-----LLSPRPSQPEPP 249 P P + S P P PP Sbjct: 856 SPVPSVVKQIASQFPPPPTPP 876 Score = 30.8 bits (68), Expect = 1.2 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 12/91 (13%) Query: 147 FLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARG 206 F A++RG L + + E + P ++ PP S V P A++ Sbjct: 577 FSEAWKRGTQLEESSKARMESMNR------------PYTSLVPPLSPQPKIVTPYTASQP 624 Query: 207 PPAVPRSLPPLDSRPVPPLKGSPGCPLGPAP 237 P +P PP P PP P P AP Sbjct: 625 SPPLPPPPPPPPPPPPPPPPPPPPLPSQSAP 655 Score = 30.4 bits (67), Expect = 1.5 Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 8/74 (10%) Query: 181 PAPTSAADPPK---SFPAAA----VLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPL 233 PAP PPK + PA V P PP +PP +P P P P Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829 Query: 234 GPAPLLSPRPSQPE 247 P P+ P P+ P+ Sbjct: 830 TP-PVPVPPPTLPK 842 Score = 30.0 bits (66), Expect = 2.0 Identities = 22/75 (29%), Positives = 26/75 (34%), Gaps = 7/75 (9%) Query: 180 QPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSR-----PVPPLKGSPGCPLG 234 +P P + A P+S PA P P PP P PP P P Sbjct: 884 KPVPANVA--PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 Query: 235 PAPLLSPRPSQPEPP 249 P P SP P + P Sbjct: 942 PPPTASPTPDKSGSP 956 Score = 29.6 bits (65), Expect = 2.6 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 14/75 (18%) Query: 183 PTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLK---------GSPGCPL 233 P PP P +A+ A P++P+ S P PPLK +P P Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF-----SAPPPPLKIHQVQHITQVAPPTPP 764 Query: 234 GPAPLLSPRPSQPEP 248 P P+ +P P Q P Sbjct: 765 PPPPIPAPLPPQAPP 779 Score = 28.9 bits (63), Expect = 4.4 Identities = 15/39 (38%), Positives = 17/39 (43%), Gaps = 3/39 (7%) Query: 214 LPPLDSRP---VPPLKGSPGCPLGPAPLLSPRPSQPEPP 249 +PPL +P P P PL P P P P P PP Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP 644 Score = 28.9 bits (63), Expect = 4.4 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 4/60 (6%) Query: 194 PAAAVLPTGAARGPPAVPRS--LPPLDSRPVPPLKGSPGCPLGPAPLLS--PRPSQPEPP 249 P V+ + + + VP + +PP P PP GS L PAP P+ S P PP Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746 Score = 28.9 bits (63), Expect = 4.4 Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 6/68 (8%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P+P PP+S + V P PA P PP S P P GSPG S Sbjct: 912 PSPDFPPPPPES---SLVFPPPPPSPVPAPPPPPPPTAS-PTPDKSGSPGKKTSKTS--S 965 Query: 241 PRPSQPEP 248 P +P P Sbjct: 966 PGGKKPPP 973 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 45.8 bits (107), Expect = 4e-05 Identities = 29/72 (40%), Positives = 34/72 (47%), Gaps = 9/72 (12%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAP 237 +A+PAP +A PP P LP+ PP+ P PPL P PP P PL P Sbjct: 533 AAEPAPGAAPPPPPPLPG---LPS-PQEAPPSAPPQAPPLPGSPEPP----PAPPL-PGD 583 Query: 238 LLSPRPSQPEPP 249 L P P P PP Sbjct: 584 LPPPPPPPPPPP 595 Score = 39.3 bits (90), Expect = 0.003 Identities = 26/74 (35%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAV-----PRSLPPLDSRPVPPLKGSPGCPLGP 235 P + + P PAA P A PP + P+ PP PPL GSP P P Sbjct: 519 PGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP 578 Query: 236 APLLSPRPSQPEPP 249 PL P P PP Sbjct: 579 -PLPGDLPPPPPPP 591 Score = 35.8 bits (81), Expect = 0.036 Identities = 42/166 (25%), Positives = 52/166 (31%), Gaps = 36/166 (21%) Query: 119 LQAELEEAEQEA----EEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAE-------- 166 L L +AE E+ E +QL + LE F A+ RR Sbjct: 411 LTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAP 470 Query: 167 --------KLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLD 218 K++EL + P A + P A P+G P VP P D Sbjct: 471 TRPSALELKVEELEEKGLIRILRGPGDAVSI-EILPVAVATPSGGDAPTPGVPTGSPSPD 529 Query: 219 SRPV------------PPLKGSPG---CPLGPAPLLSPRPSQPEPP 249 P PPL G P P P P P PEPP Sbjct: 530 LAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPP 575 Score = 30.8 bits (68), Expect = 1.2 Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 8/71 (11%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPL-GPAP 237 A P P S +PP + P LP PP P PP PVPP P P GP Sbjct: 565 APPLPGSP-EPPPAPPLPGDLP------PPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPD 617 Query: 238 LLSPRPSQPEP 248 L R S+ P Sbjct: 618 ALGRRDSELGP 628 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 43.9 bits (102), Expect = 1e-04 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 8/77 (10%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSL--PPLDSRPVPPLK------GSP 229 ++ P SA PP++ P A P A+ PP P +L PPL + P PP SP Sbjct: 487 ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 546 Query: 230 GCPLGPAPLLSPRPSQP 246 L +PL +P P P Sbjct: 547 SASLPMSPLATPPPQAP 563 Score = 38.5 bits (88), Expect = 0.006 Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 10/79 (12%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAAR-----GPPAVPRSLPPLDSRP---VPPLKGSP 229 S Q P+ A PP + PT A PP P + PP + P +PPL+ P Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409 Query: 230 GCPLGP--APLLSPRPSQP 246 P P +PL +P P P Sbjct: 410 SPPASPPLSPLATPSPQAP 428 Score = 37.7 bits (86), Expect = 0.010 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPA-VPRSLP--PLDSRPVPPLKGSP--GCPL 233 A P A PP++ PA A P A PPA P P P S P+ PL P P+ Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565 Query: 234 GPAPLLSPRPSQPEPP 249 APLL PS P P Sbjct: 566 LAAPLLQVPPSPPASP 581 Score = 36.6 bits (83), Expect = 0.021 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 189 PPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP---VPPLKGSPGCPLGP--APLLSPRP 243 PP S P A P PP P + PP + P PPL+ P P P +P +P P Sbjct: 442 PPPSPPVQA--PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499 Query: 244 SQPEP 248 P P Sbjct: 500 QAPPP 504 Score = 36.2 bits (82), Expect = 0.028 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPL 238 A P + +A PP P + P + PP+ P S PP+ PP + P PL PL Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPAS-PPMSPSATPPPQAPP--PLAAPPL 510 Query: 239 LSPRPSQPEPP 249 +P PP Sbjct: 511 QLAKPPPQAPP 521 Score = 33.9 bits (76), Expect = 0.14 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 171 LLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPG 230 L R RS + T + P +S P+A P A P+ L L V P + Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 231 CPLGP---APLLSPRPS 244 LGP +PL +P PS Sbjct: 294 PALGPLSSSPLATPSPS 310 Score = 33.1 bits (74), Expect = 0.24 Identities = 26/66 (39%), Positives = 31/66 (46%), Gaps = 3/66 (4%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P A PP++ PA A+ P A PPA P L PL + P P + L AP S Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPL-ATPSPQAPNALAVHLLQAP-FS 441 Query: 241 PRPSQP 246 P PS P Sbjct: 442 PPPSPP 447 Score = 33.1 bits (74), Expect = 0.24 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P A PP++ P VL + PP+ P S P L + PP G GP L+ Sbjct: 551 PMSPLATPPPQAPP---VLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLA 606 Query: 241 PRPSQPEPPHR 251 P P PP R Sbjct: 607 LAPGPPPPPSR 617 Score = 30.4 bits (67), Expect = 1.5 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 12/61 (19%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P +AA PP AA P +RGP PPL +G+PG PL P Sbjct: 649 PEGGAAASPPPDAELAACHPAAWSRGP------APPL------AFRGAPGAPLPWPPATG 696 Query: 241 P 241 P Sbjct: 697 P 697 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 43.9 bits (102), Expect = 1e-04 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 8/77 (10%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSL--PPLDSRPVPPLK------GSP 229 ++ P SA PP++ P A P A+ PP P +L PPL + P PP SP Sbjct: 448 ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507 Query: 230 GCPLGPAPLLSPRPSQP 246 L +PL +P P P Sbjct: 508 SASLPMSPLATPPPQAP 524 Score = 38.5 bits (88), Expect = 0.006 Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 10/79 (12%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAAR-----GPPAVPRSLPPLDSRP---VPPLKGSP 229 S Q P+ A PP + PT A PP P + PP + P +PPL+ P Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 Query: 230 GCPLGP--APLLSPRPSQP 246 P P +PL +P P P Sbjct: 371 SPPASPPLSPLATPSPQAP 389 Score = 38.1 bits (87), Expect = 0.007 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 3/82 (3%) Query: 171 LLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPG 230 L R RS + T + P +S P+A P A P+ L L V P + Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284 Query: 231 CPLGP---APLLSPRPSQPEPP 249 LGP +PL +P PS P P Sbjct: 285 PALGPLSSSPLATPSPSAPPSP 306 Score = 37.7 bits (86), Expect = 0.010 Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPA-VPRSLP--PLDSRPVPPLKGSP--GCPL 233 A P A PP++ PA A P A PPA P P P S P+ PL P P+ Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526 Query: 234 GPAPLLSPRPSQPEPP 249 APLL PS P P Sbjct: 527 LAAPLLQVPPSPPASP 542 Score = 36.6 bits (83), Expect = 0.021 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 189 PPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP---VPPLKGSPGCPLGP--APLLSPRP 243 PP S P A P PP P + PP + P PPL+ P P P +P +P P Sbjct: 403 PPPSPPVQA--PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460 Query: 244 SQPEP 248 P P Sbjct: 461 QAPPP 465 Score = 36.2 bits (82), Expect = 0.028 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPL 238 A P + +A PP P + P + PP+ P S PP+ PP + P PL PL Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPAS-PPMSPSATPPPQAPP--PLAAPPL 471 Query: 239 LSPRPSQPEPP 249 +P PP Sbjct: 472 QLAKPPPQAPP 482 Score = 33.1 bits (74), Expect = 0.24 Identities = 26/66 (39%), Positives = 31/66 (46%), Gaps = 3/66 (4%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P A PP++ PA A+ P A PPA P L PL + P P + L AP S Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPL-ATPSPQAPNALAVHLLQAP-FS 402 Query: 241 PRPSQP 246 P PS P Sbjct: 403 PPPSPP 408 Score = 33.1 bits (74), Expect = 0.24 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P A PP++ P VL + PP+ P S P L + PP G GP L+ Sbjct: 512 PMSPLATPPPQAPP---VLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLA 567 Query: 241 PRPSQPEPPHR 251 P P PP R Sbjct: 568 LAPGPPPPPSR 578 Score = 30.4 bits (67), Expect = 1.5 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 12/61 (19%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P +AA PP AA P +RGP PPL +G+PG PL P Sbjct: 610 PEGGAAASPPPDAELAACHPAAWSRGP------APPL------AFRGAPGAPLPWPPATG 657 Query: 241 P 241 P Sbjct: 658 P 658 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 43.9 bits (102), Expect = 1e-04 Identities = 65/237 (27%), Positives = 92/237 (38%), Gaps = 27/237 (11%) Query: 26 QLRDLLQDEPKLD-RIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAI 84 +L++L + LD RL R+ LQ + +E L LR RL G A+L + Sbjct: 1281 ELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEV 1340 Query: 85 KYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSL 144 QEL +VA+ KLQ +E R LG LEEA ++Q++ + L Sbjct: 1341 MRQEL-QVAQR---KLQE-QEGEFRTRERRLLG----SLEEARGTEKQQLDHA----RGL 1387 Query: 145 EAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAA 204 E L A + A LR + AE + L + +A +A G Sbjct: 1388 ELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLG 1447 Query: 205 RGPPAVPRSLPPLDSRPVP------------PLKGSPGC-PLGPAPLLSPRPSQPEP 248 R P PR +P +R P L+ SPG P P P SP +P Sbjct: 1448 RAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDP 1504 Score = 29.3 bits (64), Expect = 3.4 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 13/128 (10%) Query: 30 LLQDEPKLDRIV-RLSRKFQGLQ-----LEREACLASNYALAKENLALRPRLEMGRAALA 83 L QD+ L+R+V +L + LQ E+EA +A E L L E+ R L Sbjct: 748 LAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQ--EVARQGLE 805 Query: 84 IKYQELREVAENCADKLQRLEESMHRWSPHCA-----LGWLQAELEEAEQEAEEQMEQLL 138 + + E +L L + A L + ELE+A +EA+ Q+E L Sbjct: 806 GSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALE 865 Query: 139 LGEQSLEA 146 + EA Sbjct: 866 RAAREKEA 873 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 43.9 bits (102), Expect = 1e-04 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Query: 177 RSAQPAPTSAADPPKSFPAAAVLPTGAARGPP-AVPRSLPPLDSRPVPPLKGSPGCPLGP 235 R+ + AP +A P + P A P G R PP AV PPL P PP P Sbjct: 170 RAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPP---------AP 220 Query: 236 APLLSPRPSQPEPP 249 P P QP+PP Sbjct: 221 PQQQQPPPPQPQPP 234 Score = 37.0 bits (84), Expect = 0.016 Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 2/77 (2%) Query: 174 RRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPG-CP 232 R R A A +AA PP P P AA P PR+ + P P PG Sbjct: 113 RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAA-APARAPRAAAAAATAPPSPGPAQPGPRA 171 Query: 233 LGPAPLLSPRPSQPEPP 249 APL +P P+ PP Sbjct: 172 QRAAPLAAPPPAPAAPP 188 Score = 37.0 bits (84), Expect = 0.016 Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 1/78 (1%) Query: 174 RRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPL 233 R R+A A T+ P + P PP P + PP + P P + P Sbjct: 147 RAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA-PPAVAPPAGPRRAPPPAVA 205 Query: 234 GPAPLLSPRPSQPEPPHR 251 P L P P P PP + Sbjct: 206 AREPPLPPPPQPPAPPQQ 223 Score = 35.8 bits (81), Expect = 0.036 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 8/79 (10%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPT-------GAARGPPAVPRSLPPLDSRPVPPLKGSPG 230 +A P PT A PP + P AA P AA PP+ + P ++ PL P Sbjct: 124 AAAPPPTPAPPPPPA-PVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP 182 Query: 231 CPLGPAPLLSPRPSQPEPP 249 P P + P + PP Sbjct: 183 APAAPPAVAPPAGPRRAPP 201 Score = 35.8 bits (81), Expect = 0.036 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 10/136 (7%) Query: 119 LQAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQA--EKLQELL---- 172 L+ E EE + E E++ + + G + E+ PA + L R Q+ E+++E Sbjct: 326 LEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGP 385 Query: 173 -RRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP-VPPLKGSPG 230 + ++ PAP S + F AA+ G P S P+ P P L G+ G Sbjct: 386 HQGQDEGRGPAPGSGTR--QVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADG 443 Query: 231 CPLGPAPLLSPRPSQP 246 P G P +PS P Sbjct: 444 TPFGCPPGRKEKPSDP 459 Score = 30.0 bits (66), Expect = 2.0 Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 11/60 (18%) Query: 179 AQPAPTSAADP---PKSFPAAAVLPTGAARGPP--------AVPRSLPPLDSRPVPPLKG 227 A P P AA P P + P A P AAR PP A P+ P +P PP +G Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEG 237 >gi|8922157 proline rich 13 isoform 1 [Homo sapiens] Length = 148 Score = 43.9 bits (102), Expect = 1e-04 Identities = 31/72 (43%), Positives = 33/72 (45%), Gaps = 9/72 (12%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGC-PLGPAP 237 A P P + PP P P GA G PA P PP PVP G PGC PLGP P Sbjct: 27 AHPPPINPPFPPGPCPP----PPGAPHGNPAFPPGGPP---HPVPQ-PGYPGCQPLGPYP 78 Query: 238 LLSPRPSQPEPP 249 P P+ PP Sbjct: 79 PPYPPPAPGIPP 90 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 43.5 bits (101), Expect = 2e-04 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 17/85 (20%) Query: 175 RERSAQPAPTSAAD------PPKSFPAAAVLPTGAAR----GPPAVPRSLPPLDSRPVPP 224 R R A P P S A PP S P+ AV P R PPA+P S P S P PP Sbjct: 305 RGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAP---SGPPPP 361 Query: 225 LKGSPGCPLGPAPLLSPRPSQPEPP 249 P LG P+ P P P PP Sbjct: 362 ----PPSVLGVGPVAPPPPPPPPPP 382 Score = 37.0 bits (84), Expect = 0.016 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 5/72 (6%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP---VPPLKGSPGCPLGPAP 237 P P ++ PP P +R P A P PP SRP VPP + P P Sbjct: 292 PPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP--SRPSVAVPPPPPNRMYPPPPPA 349 Query: 238 LLSPRPSQPEPP 249 L S PS P PP Sbjct: 350 LPSSAPSGPPPP 361 Score = 32.3 bits (72), Expect = 0.40 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 5/53 (9%) Query: 200 PTGAARGPPAVPRSLPPLDSRPVPPL---KGSPGCPLGPAPLLSPRPSQPEPP 249 P + GPP P PP +S P PP +G+P P AP +P P P P Sbjct: 280 PPPSRGGPPPPPP--PPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 43.5 bits (101), Expect = 2e-04 Identities = 50/179 (27%), Positives = 74/179 (41%), Gaps = 46/179 (25%) Query: 74 RLEMGRAALAIKY-QELREVAENCADKLQRLEESMHRWSPHCALGWLQAE--LEEAEQEA 130 +++MG+ +L ++ Q + E+ D QR S SP C W + E L++ E+E Sbjct: 313 KVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSP-C---WKKQEQKLDDEEEEK 368 Query: 131 EEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPP 190 +E+ E+ GE+ E R AE++ + E P PP Sbjct: 369 KEEEEKDKEGEEKEE----------------RAVAEEMMPAAEKEEAKLPP-------PP 405 Query: 191 KSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEPP 249 + PA P+ P LPP + P PPL P P+ P PL PS P PP Sbjct: 406 LTPPA------------PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL----PSPPPPP 448 Score = 35.4 bits (80), Expect = 0.047 Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 30/138 (21%) Query: 141 EQSLEAFLPAF-QRGRALAHLRRTQAEKLQELLRRRERSAQPAPT---SAADPPKSFPAA 196 E+S +PA R R L +Q + + E ++ P PT + PP+ P Sbjct: 454 EESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTV 513 Query: 197 A-------------VLPTGAARGPPAV----------PRSLPPLDSRPV--PPLKGSPGC 231 A ++P +AR + P P ++ PV PP+ SP Sbjct: 514 APKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV 573 Query: 232 PLGPAPLLSPRPSQPEPP 249 P PAP+ SP P P PP Sbjct: 574 PQEPAPVPSP-PRAPTPP 590 Score = 31.6 bits (70), Expect = 0.68 Identities = 34/103 (33%), Positives = 40/103 (38%), Gaps = 19/103 (18%) Query: 149 PAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGP- 207 PA +RG R QA L ELLRR + A AP S A P + + P G GP Sbjct: 177 PARKRGEEGTE-RMVQA--LTELLRRAQ--APQAPRSRACEPSTPRRSRGRPPGRPAGPC 231 Query: 208 -------------PAVPRSLPPLDSRPVPPLKGSPGCPLGPAP 237 +P+ PP PV GS C GP P Sbjct: 232 RRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGP 274 Score = 30.4 bits (67), Expect = 1.5 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 3/70 (4%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRS--LPPLDSRPVPPLKGSPGCPLGPAPL 238 P P A PP + PA + R P P L +S PP G+P P P Sbjct: 625 PPPPPAPSPPPA-PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPP 683 Query: 239 LSPRPSQPEP 248 P++PEP Sbjct: 684 ADDSPAEPEP 693 Score = 28.9 bits (63), Expect = 4.4 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 13/75 (17%) Query: 177 RSAQPAPTSAADPPKSFPAAAVLPTGAARGPP--AVPRSLPPLDSRPVPPLKGSPGCPLG 234 RS +P+P + PP + + + + R PP +V +L P PP G Sbjct: 1912 RSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP---------G 1962 Query: 235 PAPLLSPRPSQPEPP 249 PAP SP P + P Sbjct: 1963 PAP--SPPPPEDLGP 1975 Score = 28.1 bits (61), Expect = 7.6 Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 9/79 (11%) Query: 180 QPAPTSAADP-PKSFPAAAV-LPTGAARGPPAVPRSLPPLDSRPVP-------PLKGSPG 230 +P SA P P+SF A + +P + P S PL S P P G P Sbjct: 1846 RPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPD 1905 Query: 231 CPLGPAPLLSPRPSQPEPP 249 P P P P P PP Sbjct: 1906 FPAPPRRSRRPSPLAPRPP 1924 >gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] Length = 1096 Score = 42.7 bits (99), Expect = 3e-04 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 18/135 (13%) Query: 120 QAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSA 179 +A++EE+EQ+A E ++ + A Q +A R + ++L+ +++ A Sbjct: 487 KAKVEESEQKAAEFSKKF-------DEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQA 539 Query: 180 QPAPTSAADPPKSFPAAAVLP-TGAARGPPAVP----RSLPPLDSRPVPPLKGSPGCPLG 234 Q +S+ P PAA LP G PPA P LPP P PPL G G P Sbjct: 540 QVLSSSSGIPGP--PAAPPLPGVGPPPPPPAPPLPGGAPLPP----PPPPLPGMMGIPPP 593 Query: 235 PAPLLSPRPSQPEPP 249 P P L P PP Sbjct: 594 PPPPLLFGGPPPPPP 608 >gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] Length = 1101 Score = 42.7 bits (99), Expect = 3e-04 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 18/135 (13%) Query: 120 QAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSA 179 +A++EE+EQ+A E ++ + A Q +A R + ++L+ +++ A Sbjct: 487 KAKVEESEQKAAEFSKKF-------DEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQA 539 Query: 180 QPAPTSAADPPKSFPAAAVLP-TGAARGPPAVP----RSLPPLDSRPVPPLKGSPGCPLG 234 Q +S+ P PAA LP G PPA P LPP P PPL G G P Sbjct: 540 QVLSSSSGIPGP--PAAPPLPGVGPPPPPPAPPLPGGAPLPP----PPPPLPGMMGIPPP 593 Query: 235 PAPLLSPRPSQPEPP 249 P P L P PP Sbjct: 594 PPPPLLFGGPPPPPP 608 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 42.7 bits (99), Expect = 3e-04 Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 15/84 (17%) Query: 180 QPAPTSAADPPKSFPAA---------AVLPTGAARGPPAVPR---SLPPLDSRPVPPLKG 227 +P+P+ + +P K FPA AV P GPP PR S P S P P K Sbjct: 280 KPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKP 339 Query: 228 SPGC---PLGPAPLLSPRPSQPEP 248 +P P P P +SP P +P P Sbjct: 340 APSVSPGPWKPIPSVSPGPWKPTP 363 Score = 34.3 bits (77), Expect = 0.11 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 32/102 (31%) Query: 179 AQPAPTSAADPPKSFPAA-----AVLPTGAARGP-PAVPRSL------------------ 214 ++PA S+ +PPKS P A +P+ + P P P S+ Sbjct: 177 SKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPET 236 Query: 215 --PPLDSRPVPPLKGSPGCPLGPAPLLSP------RPSQPEP 248 PP S P P+ + P GP+P SP R + PEP Sbjct: 237 LGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEP 278 Score = 33.5 bits (75), Expect = 0.18 Identities = 25/83 (30%), Positives = 30/83 (36%), Gaps = 3/83 (3%) Query: 170 ELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSP 229 E L S+ +P AA P P+ A P P P S P K P Sbjct: 235 ETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFP 294 Query: 230 GC---PLGPAPLLSPRPSQPEPP 249 P PAP +SP +P PP Sbjct: 295 AVSPEPRRPAPAVSPGSWKPGPP 317 Score = 31.6 bits (70), Expect = 0.68 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 14/79 (17%) Query: 180 QPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGP---A 236 Q P ++A+P KS PA ++ G P S P P+ P K PG + P Sbjct: 115 QKIPCNSAEP-KSIPALSM--ETQKLGSVLSPESPKPTPLTPLEPQK--PGSVVSPELQT 169 Query: 237 PLLSPRPSQ------PEPP 249 PL SP PS+ PEPP Sbjct: 170 PLPSPEPSKPASVSSPEPP 188 Score = 30.8 bits (68), Expect = 1.2 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 16/79 (20%) Query: 177 RSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSR------PVPPLKGSPG 230 +S+ +P+S PP S P GPP + ++ P L PV P PG Sbjct: 371 KSSSVSPSSWKSPPAS-------PESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPG 423 Query: 231 CPLGP---APLLSPRPSQP 246 PL P +P SP +P Sbjct: 424 PPLSPEIRSPAGSPELRKP 442 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 42.4 bits (98), Expect = 4e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 186 AADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP---VPPLKGSPGCPLGP--APLLS 240 A PP++ PA A P PP P + PP + P +PPL+ P P P +PL + Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647 Query: 241 PRPSQP 246 P P P Sbjct: 648 PSPQAP 653 Score = 38.1 bits (87), Expect = 0.007 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP-VPPLKGSPGCPLGPA 236 ++ P SA PP++ P A P PPA P P P VPPL +P + P+ Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771 Query: 237 PLLS-PRPSQPEPP 249 P S P +PP Sbjct: 772 PPASLPMSPLAKPP 785 Score = 37.4 bits (85), Expect = 0.012 Identities = 29/74 (39%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPA-VPRSLP--PLDSRPVPPLKGSP--GCPLGP 235 P A PP++ PA A P A PPA P P P S P+ PL P P+ Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836 Query: 236 APLLSPRPSQPEPP 249 APLL PS P P Sbjct: 837 APLLQVPPSPPASP 850 Score = 36.6 bits (83), Expect = 0.021 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 189 PPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP---VPPLKGSPGCPLGP--APLLSPRP 243 PP S P A P PP P + PP + P PPL+ P P P +P +P P Sbjct: 667 PPPSPPVQA--PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724 Query: 244 SQPEP 248 P P Sbjct: 725 QAPPP 729 Score = 35.8 bits (81), Expect = 0.036 Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 7/86 (8%) Query: 171 LLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPG 230 L R RS + T + P +S P+A P A P+ L L V P + Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 231 CPLGP---APLLSPRPS----QPEPP 249 LGP +PL +P PS +P PP Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPP 319 Score = 34.7 bits (78), Expect = 0.081 Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 8/94 (8%) Query: 155 RALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSL 214 RA AH + + + LQ L + + A P S P A P+G P + Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP------V 317 Query: 215 PPLDSRPVP-PLKGSPGCPLG-PAPLLSPRPSQP 246 PP D+ P P P PL P PL P PS P Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351 Score = 34.7 bits (78), Expect = 0.081 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 18/89 (20%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRP---VPPLKGSPGCPLG 234 S P S A P + P V P+ A PP P + PP + P PPL+ P P Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744 Query: 235 PA------------PLLSPRPSQ--PEPP 249 P PLL+ P Q P PP Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPP 773 Score = 34.7 bits (78), Expect = 0.081 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Query: 183 PTSAADPPKSFPAA--AVLPTGA-ARGPPAVPRSL--PPLDSRPVPPLK------GSPGC 231 P A PP P + A LP A+ PP P +L PPL + P PP SP Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817 Query: 232 PLGPAPLLSPRPSQP 246 L +PL +P P P Sbjct: 818 SLPMSPLATPPPQAP 832 Score = 33.1 bits (74), Expect = 0.24 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P A PP++ P VL + PP+ P S P L + PP G GP L+ Sbjct: 820 PMSPLATPPPQAPP---VLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLA 875 Query: 241 PRPSQPEPPHR 251 P P PP R Sbjct: 876 LAPGPPPPPSR 886 Score = 31.2 bits (69), Expect = 0.89 Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P A PP++ P A+ P A PPA P L PL + P P + L AP S Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASP-PLSPL-ATPSPQAPNALAVHLLQAP-FS 666 Query: 241 PRPSQP 246 P PS P Sbjct: 667 PPPSPP 672 Score = 30.8 bits (68), Expect = 1.2 Identities = 29/90 (32%), Positives = 34/90 (37%), Gaps = 3/90 (3%) Query: 161 RRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPP-AVPRSLPPLDS 219 R+ A L L + P+ T A P AA LP PP A P L P Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348 Query: 220 RPVPPLKGSPGCPLGPAPLLSPRPSQPEPP 249 P L+ P P P P +P PS PP Sbjct: 349 SAPPSLQTLPSPPATP-PSQAP-PSMTTPP 376 Score = 30.8 bits (68), Expect = 1.2 Identities = 22/74 (29%), Positives = 26/74 (35%), Gaps = 7/74 (9%) Query: 180 QPAPTSAADPPKSFPAAAVLPTGAA----RGPPAVPRSLPPLDSRPVPPLKGSPGCPLGP 235 Q P+ PP P++ P A PP PPL PP + P L P Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629 Query: 236 APLLSPRPSQPEPP 249 L PS P P Sbjct: 630 ---LQAPPSPPASP 640 Score = 30.4 bits (67), Expect = 1.5 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 12/61 (19%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLS 240 P +AA PP AA P +RGP PPL +G+PG PL P Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGP------APPL------AFRGAPGAPLPWPPATG 965 Query: 241 P 241 P Sbjct: 966 P 966 Score = 28.9 bits (63), Expect = 4.4 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAP 237 S Q P+ A PP P + P A PP++ +++PP+ VP SP P+P Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQA--PPSL-QTIPPIQ---VPHSLTSPSLQAPPSP 406 Query: 238 L 238 L Sbjct: 407 L 407 Score = 28.5 bits (62), Expect = 5.8 Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 10/76 (13%) Query: 176 ERSAQPAPTSAADPPKSF--PAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPL 233 E + AP S PP S P LP+ A PP + + PL + P +P CP Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLA---PPPLQTASAPLTT----PHLETPPCP- 564 Query: 234 GPAPLLSPRPSQPEPP 249 P PL +P PP Sbjct: 565 APCPLQAPPSPLTTPP 580 >gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 [Homo sapiens] Length = 809 Score = 42.0 bits (97), Expect = 5e-04 Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 5/123 (4%) Query: 118 WLQA-ELEEAEQEAEEQMEQLLLGEQSLEAFLPA--FQRGRALAHLRRTQAEKLQELLRR 174 W+Q L+E E E E + ++L L +RG + +L + + Sbjct: 24 WIQGLPLKEEEILPEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDRDPTLATPPA 83 Query: 175 RERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSL--PPLDSRPVPPLKGSPGCP 232 + A P+ A +P AV P G P P L PP + P PP SPG P Sbjct: 84 GQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPP 143 Query: 233 LGP 235 LGP Sbjct: 144 LGP 146 >gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 [Homo sapiens] Length = 910 Score = 42.0 bits (97), Expect = 5e-04 Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 5/123 (4%) Query: 118 WLQA-ELEEAEQEAEEQMEQLLLGEQSLEAFLPA--FQRGRALAHLRRTQAEKLQELLRR 174 W+Q L+E E E E + ++L L +RG + +L + + Sbjct: 24 WIQGLPLKEEEILPEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDRDPTLATPPA 83 Query: 175 RERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSL--PPLDSRPVPPLKGSPGCP 232 + A P+ A +P AV P G P P L PP + P PP SPG P Sbjct: 84 GQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPP 143 Query: 233 LGP 235 LGP Sbjct: 144 LGP 146 >gi|9945318 MAX binding protein [Homo sapiens] Length = 582 Score = 42.0 bits (97), Expect = 5e-04 Identities = 43/134 (32%), Positives = 59/134 (44%), Gaps = 15/134 (11%) Query: 125 EAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPT 184 + +Q A E+ E+L L EQ E ++ +LA L T + + + PAP Sbjct: 18 QQQQRAREEQERLRL-EQEREQ---EQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPP 73 Query: 185 SAADPPKSFPAA-AVLPTGAARG-------PPAVPRSLPPLDSRP-VPPLKGSPGCPL-G 234 A PP + PA V+P PP +P + PL P P L G+PG + Sbjct: 74 PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKE 133 Query: 235 PAPLLSPRPSQPEP 248 PAPL S RP P P Sbjct: 134 PAPLPS-RPQVPTP 146 Score = 36.2 bits (82), Expect = 0.028 Identities = 39/118 (33%), Positives = 51/118 (43%), Gaps = 8/118 (6%) Query: 134 MEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSF 193 +E LL + LE QR R R + E+ QE ++ A+ A T + P+ Sbjct: 3 IETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQ-KKANSLARLAHTLPVEEPRM- 60 Query: 194 PAAAVLPTGAARGPPAVPRSLP---PLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEP 248 A LP PPA P L PL P+P + SP PL P P L P +QP P Sbjct: 61 -EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQ-PLPPPPPL-PAAAQPLP 115 Score = 31.2 bits (69), Expect = 0.89 Identities = 37/153 (24%), Positives = 55/153 (35%), Gaps = 9/153 (5%) Query: 88 ELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLL--GEQSLE 145 E+ +A QRL E H S + + L + Q ++Q GE +++ Sbjct: 281 EMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNID 340 Query: 146 AFLPAFQRGRALAHL-RRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAA 204 + + G L R Q E L+ L + P P P P + LP Sbjct: 341 EDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPH----PHPHPHSVALPPAHL 396 Query: 205 RGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAP 237 P+ PL + P PP +P L PAP Sbjct: 397 PVQQQQPQQKTPLPAPPPPP--AAPAQTLVPAP 427 Score = 30.8 bits (68), Expect = 1.2 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 12/112 (10%) Query: 143 SLEAFLPA--FQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLP 200 S+E L A F +A R + ++ L + RE+ + A + A A LP Sbjct: 2 SIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLAR-------LAHTLP 54 Query: 201 TGAAR-GPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLL--SPRPSQPEPP 249 R P +P S P P PPL + P P++ SP+P P PP Sbjct: 55 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPP 106 Score = 27.7 bits (60), Expect = 9.9 Identities = 41/141 (29%), Positives = 59/141 (41%), Gaps = 24/141 (17%) Query: 115 ALGWLQAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRR 174 AL ++Q+ L+ E+E E +ME+L + + + QR L H +Q + E+ R Sbjct: 264 ALRYIQS-LKRKEKEYEHEMERLAREKIATQ------QRLAELKH-ELSQWMDVLEIDRV 315 Query: 175 RERSAQP----APTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPG 230 ++ QP A TS A + + A GPP L RP P L S Sbjct: 316 LRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPK-------LSHRPQPELLKS-- 366 Query: 231 CPLGPAPLLSPRPSQPEP-PH 250 P P +P P P P PH Sbjct: 367 --TLPPPSTTPAPLPPHPHPH 385 >gi|21071077 dishevelled-associated activator of morphogenesis 1 [Homo sapiens] Length = 1078 Score = 42.0 bits (97), Expect = 5e-04 Identities = 42/138 (30%), Positives = 60/138 (43%), Gaps = 16/138 (11%) Query: 119 LQAELEEAE-------QEAEEQMEQLLLGEQSLEAFLPAFQRGRA-LAHLRRTQAEKLQE 170 LQ +LE+ E QE EE M+ L ++ LE ++ + +A L +L E Sbjct: 462 LQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADL----TAQLHE 517 Query: 171 LLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPG 230 L RR ++ P S P FP++ PP +P + P P+PP G P Sbjct: 518 LSRRAVCASIPGGPSPGAPGGPFPSSVPGSLLPPPPPPPLPGGMLPPPPPPLPP--GGPP 575 Query: 231 CPLGPAPL--LSPRPSQP 246 P GP PL + P P P Sbjct: 576 PPPGPPPLGAIMPPPGAP 593 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 41.6 bits (96), Expect = 7e-04 Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 9/82 (10%) Query: 177 RSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAV---PR---SLPPLDSRPVPPLKGSP- 229 + A P + PK PAA LP GA P A P+ + P L P PP P Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089 Query: 230 --GCPLGPAPLLSPRPSQPEPP 249 G P P+P +P P PP Sbjct: 1090 PKGGPATPSPKGAPMPPAATPP 1111 Score = 37.7 bits (86), Expect = 0.010 Identities = 26/68 (38%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 181 PAPTSAADP-PKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPL-KGSPGCPLGPAPL 238 P P + P PK PAA P GA+ P A P S P S PL KG+P P P Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS--PKGSPAATPLPKGAPTTPAATLPS 1066 Query: 239 LSPRPSQP 246 P+ P Sbjct: 1067 PKGGPATP 1074 Score = 36.2 bits (82), Expect = 0.028 Identities = 27/70 (38%), Positives = 30/70 (42%), Gaps = 6/70 (8%) Query: 181 PAPTSAADP-PKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLL 239 P P +A P PK PA P GA P A P S P PP KG+P P P Sbjct: 1080 PTPPAATPPSPKGGPATPS-PKGAPMPPAATPPS--PKGGLATPPHKGAPTTPAATPP-- 1134 Query: 240 SPRPSQPEPP 249 SP+ PP Sbjct: 1135 SPKGGLATPP 1144 Score = 35.4 bits (80), Expect = 0.047 Identities = 27/81 (33%), Positives = 31/81 (38%), Gaps = 10/81 (12%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRS------LPPLDSRPVPPLKGSP-- 229 S+ P A PK PA+ P GA P A P S P P PP P Sbjct: 915 SSSPKKARATPAPKGIPASPS-PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973 Query: 230 -GCPLGPAPLLSPRPSQPEPP 249 G P P+P +P P PP Sbjct: 974 KGGPATPSPKGAPTPPAATPP 994 Score = 34.3 bits (77), Expect = 0.11 Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 5/66 (7%) Query: 186 AADPPKSFPAAAVLPTGAARGPPAV--PRSLPPLDSRPVPPLKGSPGCPLGPAPLLSPRP 243 A P K P AV+ + +G PA P+ P + P KGSPG P P +P P Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT---PPPKGAPTP 1335 Query: 244 SQPEPP 249 PP Sbjct: 1336 PAVTPP 1341 Score = 33.9 bits (76), Expect = 0.14 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 10/79 (12%) Query: 179 AQPAPTSAADPPKSFPA------AAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCP 232 A P+P A P + P A P GA P A P S P PP KG+P P Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS--PKGGPATPPPKGAPTPP 1267 Query: 233 LGPAPLLSPRPSQPEPPHR 251 P L + PPH+ Sbjct: 1268 AATPPSL--KGGLATPPHK 1284 Score = 31.2 bits (69), Expect = 0.89 Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 13/84 (15%) Query: 178 SAQPAPTSAADPPKS------FPAAAVLPTGAARGPPAVPRSLPPLDS---RPVPPLKGS 228 S + APT A P S P+ PT A PP+ P+ P S P PP Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS-PKGGPATPSPKGAPTPPAATP 993 Query: 229 P---GCPLGPAPLLSPRPSQPEPP 249 P G P P+P +P P PP Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPP 1017 Score = 30.8 bits (68), Expect = 1.2 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 4/69 (5%) Query: 182 APTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPV--PPLKGSPGCPLGPAPLL 239 APT+ A P S L T +G P P + PP + PP KG+P P P Sbjct: 1125 APTTPAATPPSPKGG--LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182 Query: 240 SPRPSQPEP 248 + P P Sbjct: 1183 KGGLATPSP 1191 Score = 30.8 bits (68), Expect = 1.2 Identities = 22/68 (32%), Positives = 24/68 (35%), Gaps = 2/68 (2%) Query: 182 APTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLSP 241 APT A P S P PAV P P KG+P P P SP Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP--SP 1320 Query: 242 RPSQPEPP 249 + S PP Sbjct: 1321 KGSPGTPP 1328 Score = 30.8 bits (68), Expect = 1.2 Identities = 29/94 (30%), Positives = 33/94 (35%), Gaps = 24/94 (25%) Query: 181 PAPTSAADP-PKSFPAAAVLPTGAARGPPAVPRS------LPPLDSRPVPPL------KG 227 P P P PK PA + P GA P A P S PP P PP KG Sbjct: 1287 PNPAVVTPPSPKGGPATSP-PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345 Query: 228 SP----------GCPLGPAPLLSPRPSQPEPPHR 251 +P G P P+ P P P H+ Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379 Score = 30.4 bits (67), Expect = 1.5 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 17/80 (21%) Query: 178 SAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPP----LKGSP-GCP 232 S + AP ++A PK PA T +++G P +P PP P P SP P Sbjct: 1442 SLKKAPATSA--PKGGPA-----TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494 Query: 233 LGPAPLLSPR-----PSQPE 247 PAP+ +P PS P+ Sbjct: 1495 ATPAPMGAPTLPAVIPSSPK 1514 Score = 30.0 bits (66), Expect = 2.0 Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 13/78 (16%) Query: 182 APTSAADPPKSFPAAAVLPTGAARGPPAVPR----------SLPPLDSRPVPPLKGSPGC 231 +P PPK P +V+ + PA P S P +R P KG Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG---I 930 Query: 232 PLGPAPLLSPRPSQPEPP 249 P P+P +P P PP Sbjct: 931 PASPSPKGAPTPPAATPP 948 Score = 28.1 bits (61), Expect = 7.6 Identities = 27/94 (28%), Positives = 36/94 (38%), Gaps = 19/94 (20%) Query: 176 ERSAQPAPTSAADPPKSFP-----AAAVLPTGAAR----------GPPAVPRSLPPLDSR 220 + S P+P++ A P P + LP G A GPP P +L Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122 Query: 221 PVPPLKGSP--GCPLGPAPLL--SPRPSQPEPPH 250 P LKG+P PL L S + S PP+ Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156 Score = 28.1 bits (61), Expect = 7.6 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 6/73 (8%) Query: 175 RERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLG 234 +E A P+ A+ PP AV P+ P +PP + P P +P Sbjct: 1568 KEAPATPSSKEASSPP------AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621 Query: 235 PAPLLSPRPSQPE 247 P+P P P+ Sbjct: 1622 PSPEKGPATPAPK 1634 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 41.2 bits (95), Expect = 9e-04 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 179 AQPAPTSAADPP--KSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPA 236 A P P +A PP P LP ++ GPP P PPL + P PP G P P P Sbjct: 668 APPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP-PPLPNSPAPPNPGGPP-PAPPP 725 Query: 237 PLLSPRP 243 P L+P P Sbjct: 726 PGLAPPP 732 Score = 38.1 bits (87), Expect = 0.007 Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 6/85 (7%) Query: 172 LRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPR----SLPPLDSRPVPPLKG 227 L+ E A + PP S P LP+G PA P + PPL P PP Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690 Query: 228 SPGCPLGPAPLLSPRP--SQPEPPH 250 P GP P P P + P PP+ Sbjct: 691 PPPSSAGPPPPPPPPPLPNSPAPPN 715 Score = 37.7 bits (86), Expect = 0.010 Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 13/93 (13%) Query: 166 EKLQELLRRRERSAQPAPTSAADPP-------KSFPAAAVLPTGAARG---PPAVPRSLP 215 + ++ + ++++ P P S PP PA + P A PP P LP Sbjct: 632 QPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP 691 Query: 216 PLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEP 248 P S PP P P PAP P P P P Sbjct: 692 PPSSAGPPPPPPPPPLPNSPAP---PNPGGPPP 721 Score = 29.6 bits (65), Expect = 2.6 Identities = 26/77 (33%), Positives = 27/77 (35%), Gaps = 14/77 (18%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKG--------SPGCP 232 P P+SA PP P LP A P P PP PP G S CP Sbjct: 691 PPPSSAGPPPP--PPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCP 748 Query: 233 LGPAPLLSPRPSQPEPP 249 PA PS P P Sbjct: 749 RKPA----IEPSCPMKP 761 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 41.2 bits (95), Expect = 9e-04 Identities = 28/69 (40%), Positives = 33/69 (47%), Gaps = 7/69 (10%) Query: 179 AQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPL 238 A+P PT A P P P G AR P P S P+ ++PVP L+GSP PL Sbjct: 1198 AEPPPTDLAHLPPLPP-----PEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPL 1252 Query: 239 LSPRPSQPE 247 P P PE Sbjct: 1253 --PGPGSPE 1259 Score = 33.9 bits (76), Expect = 0.14 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 7/68 (10%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCP--LGPAPL 238 P P PK A A LP+G+A PA P +P L PG P LG +P Sbjct: 1272 PKPPPPPTAPKPVKAVAGLPSGSAGPSPA-----PSPARQPPAALAKPPGTPPSLGASPA 1326 Query: 239 LSPRPSQP 246 P P P Sbjct: 1327 KPPSPGAP 1334 Score = 32.3 bits (72), Expect = 0.40 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 181 PAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDS-RPVPPLKGSPGCPLGPAPLL 239 P PTS P P + + PP P+ PP + +PV + G P GP+P Sbjct: 1243 PTPTSKKVPLPG-PGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAP 1301 Query: 240 SPRPSQP 246 SP P Sbjct: 1302 SPARQPP 1308 Score = 31.6 bits (70), Expect = 0.68 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 21/101 (20%) Query: 163 TQAEKLQELLRRRERSAQPAPTSAADPPKSF-----PAAAVLPTGAARGPPAVPRSLPPL 217 T+++ ++ + +ER A P P PP S P GPP +P PP Sbjct: 1143 TESDTVKRRPKAKEREAGPEPP----PPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPA 1198 Query: 218 DSRP--------VPPLKGSPGCPLGPAPLLSPRP--SQPEP 248 + P +PP +G P P +SP+P +QP P Sbjct: 1199 EPPPTDLAHLPPLPPPEGEARKPAKPP--VSPKPVLTQPVP 1237 >gi|40353727 synaptopodin isoform A [Homo sapiens] Length = 903 Score = 41.2 bits (95), Expect = 9e-04 Identities = 36/103 (34%), Positives = 43/103 (41%), Gaps = 18/103 (17%) Query: 162 RTQAEKLQELLRR------RERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLP 215 R + +LQ LL R R +SA P A +P P A P PP PR Sbjct: 747 RPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRA--PPPPPPPPPPPPRMRS 804 Query: 216 PLDSRP----VP-----PLKGSPGCPLGPAPLLSPRPSQPEPP 249 P +RP VP P+ SP P GP+ SPR P PP Sbjct: 805 PQPARPGSAAVPGAAFAPIPRSP-LPAGPSSCTSPRSPLPAPP 846 Score = 33.9 bits (76), Expect = 0.14 Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 176 ERSAQPA-PTSAADPPKSFPAAAVLPT--GAARGPPAVPRSLPPLDSRPVPPLKGSPGCP 232 ERS P P + A PP A + AAR A PRS + RP P + P P Sbjct: 734 ERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPP 793 Query: 233 LGPAP---LLSPRPSQP 246 P P + SP+P++P Sbjct: 794 PPPPPPPRMRSPQPARP 810 Score = 30.8 bits (68), Expect = 1.2 Identities = 30/86 (34%), Positives = 35/86 (40%), Gaps = 16/86 (18%) Query: 180 QPAPTS--AADP--PKSFPAAAVLPTGAARGPPAVP---RSLPPLDSRP---------VP 223 +PA S AA P P S LP GA PA+P RS P L + P V Sbjct: 579 EPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638 Query: 224 PLKGSPGCPLGPAPLLSPRPSQPEPP 249 P G P+ P+ SPR Q P Sbjct: 639 PPYGGDISPVSPSRAWSPRAKQAPRP 664 >gi|34577114 cytomatrix protein p110 [Homo sapiens] Length = 957 Score = 41.2 bits (95), Expect = 9e-04 Identities = 32/147 (21%), Positives = 74/147 (50%), Gaps = 13/147 (8%) Query: 34 EPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAIKYQELREVA 93 + ++DR++ + ++ + + +++ +A E+L LR + + +K+ + E Sbjct: 723 QAEVDRLLEILKEVENEKNDKDKKIAE-----LESLTLRHMKDQNKKVANLKHNQQLEKK 777 Query: 94 ENCA--DKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSLEAFLPAF 151 +N ++++R E+SM S H + L LE+ QE + +L +QSL Sbjct: 778 KNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLA------ 831 Query: 152 QRGRALAHLRRTQAEKLQELLRRRERS 178 ++ LA+LR + ++L+E+L ++ + Sbjct: 832 EKEAHLANLRIERRKQLEEILEMKQEA 858 >gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4 [Homo sapiens] Length = 456 Score = 41.2 bits (95), Expect = 9e-04 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 25/93 (26%) Query: 180 QPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSR-----PVPPLK-GSPG--- 230 Q +P +AA+PP S P ++LPT G P+ P + PPLD+ P PP + +PG Sbjct: 66 QESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAAPGTDG 125 Query: 231 ----------------CPLGPAPLLSPRPSQPE 247 PL P+ +++ + + PE Sbjct: 126 WGLPSGGGGAQDAWLRTPLAPSEMITAQSALPE 158 Score = 35.4 bits (80), Expect = 0.047 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 4/60 (6%) Query: 193 FPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLSPRPSQ-PEPPHR 251 FP A GAA PP P PP P P G+P P P PL + + PEPP + Sbjct: 61 FPLALQESPGAAAEPPPSP---PPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQ 117 >gi|21237808 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform b [Homo sapiens] Length = 1130 Score = 41.2 bits (95), Expect = 9e-04 Identities = 52/172 (30%), Positives = 72/172 (41%), Gaps = 19/172 (11%) Query: 80 AALAIKYQELREVAENCADKLQRL--EESMHRWSPHCALGWLQAELEEAEQEAEEQMEQL 137 AA A+K + L V E L L E M + L EE E + + E L Sbjct: 898 AAAAVKAKHLAAVEERKIKSLVALLVETQMKK------LEIKLRHFEELETIMDREREAL 951 Query: 138 LLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAA 197 Q L A AF + R + + Q++ ++++ QP P A PP S P Sbjct: 952 EYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQ---QPPP---ALPPGSQP--- 1002 Query: 198 VLPTGAARGPPAVPR-SLPPLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEP 248 + PTGAA GPPAV ++ P P P G+P LGP+ + S P Sbjct: 1003 IPPTGAA-GPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1053 >gi|21237805 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens] Length = 1214 Score = 41.2 bits (95), Expect = 9e-04 Identities = 52/172 (30%), Positives = 72/172 (41%), Gaps = 19/172 (11%) Query: 80 AALAIKYQELREVAENCADKLQRL--EESMHRWSPHCALGWLQAELEEAEQEAEEQMEQL 137 AA A+K + L V E L L E M + L EE E + + E L Sbjct: 867 AAAAVKAKHLAAVEERKIKSLVALLVETQMKK------LEIKLRHFEELETIMDREREAL 920 Query: 138 LLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAA 197 Q L A AF + R + + Q++ ++++ QP P A PP S P Sbjct: 921 EYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQ---QPPP---ALPPGSQP--- 971 Query: 198 VLPTGAARGPPAVPR-SLPPLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEP 248 + PTGAA GPPAV ++ P P P G+P LGP+ + S P Sbjct: 972 IPPTGAA-GPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGP 1022 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,129,868 Number of Sequences: 37866 Number of extensions: 729198 Number of successful extensions: 11786 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 279 Number of HSP's successfully gapped in prelim test: 1103 Number of HSP's that attempted gapping in prelim test: 7241 Number of HSP's gapped (non-prelim): 4479 length of query: 251 length of database: 18,247,518 effective HSP length: 100 effective length of query: 151 effective length of database: 14,460,918 effective search space: 2183598618 effective search space used: 2183598618 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.