Guide to the Human Genome
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Search of human proteins with 117553608

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117553619 solute carrier family 39, member 7 [Homo sapiens]        979   0.0  
gi|117553608 solute carrier family 39, member 7 [Homo sapiens]        979   0.0  
gi|190014617 solute carrier family 39 (zinc transporter), member...   194   1e-49
gi|40255101 solute carrier family 39 (zinc transporter), member ...   189   5e-48
gi|115430259 solute carrier family 39 (zinc transporter), member...   146   3e-35
gi|115430255 solute carrier family 39 (zinc transporter), member...   146   3e-35
gi|223633939 solute carrier family 39 (zinc transporter), member...   140   3e-33
gi|206597541 solute carrier family 39 (metal ion transporter), m...   130   3e-30
gi|206597539 solute carrier family 39 (metal ion transporter), m...   130   3e-30
gi|223633937 solute carrier family 39 (zinc transporter), member...   127   3e-29
gi|187936949 solute carrier family 39 (zinc transporter), member...   112   6e-25
gi|55741750 solute carrier family 39 (zinc transporter), member ...   112   6e-25
gi|205830424 solute carrier family 39 (zinc transporter), member...   102   1e-21
gi|190360568 solute carrier family 39 (zinc transporter), member...   102   1e-21
gi|190358541 solute carrier family 39 (zinc transporter), member...   100   3e-21
gi|153252201 solute carrier family 39 (zinc transporter), member...    95   1e-19
gi|205830426 solute carrier family 39 (zinc transporter), member...    93   5e-19
gi|153252214 solute carrier family 39 (zinc transporter), member...    86   6e-17
gi|24586665 solute carrier family 39 (zinc transporter), member ...    85   2e-16
gi|205830407 solute carrier family 39 (zinc transporter), member...    85   2e-16
gi|205830403 solute carrier family 39 (zinc transporter), member...    85   2e-16
gi|205830405 solute carrier family 39 (zinc transporter), member...    84   2e-16
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]        61   2e-09
gi|156231037 kininogen 1 isoform 1 [Homo sapiens]                      61   2e-09
gi|222080086 zinc transporter like 2 [Homo sapiens]                    60   4e-09
gi|40255009 zinc transporter like 2 [Homo sapiens]                     60   4e-09
gi|40254928 solute carrier family 39 (zinc transporter), member ...    52   2e-06
gi|59938776 cAMP responsive element binding protein 5 isoform de...    52   2e-06
gi|59938774 cAMP responsive element binding protein 5 isoform be...    52   2e-06
gi|59938772 cAMP responsive element binding protein 5 isoform ga...    52   2e-06

>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
          Length = 469

 Score =  979 bits (2530), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60
           MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH
Sbjct: 1   MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60

Query: 61  AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120
           AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES
Sbjct: 61  AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120

Query: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
           GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL
Sbjct: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180

Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240
           LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240

Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300
           KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP
Sbjct: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300

Query: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360
           VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV
Sbjct: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360

Query: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420
           PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL
Sbjct: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420

Query: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469
           PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE
Sbjct: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469


>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
          Length = 469

 Score =  979 bits (2530), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60
           MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH
Sbjct: 1   MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60

Query: 61  AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120
           AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES
Sbjct: 61  AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120

Query: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
           GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL
Sbjct: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180

Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240
           LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240

Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300
           KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP
Sbjct: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300

Query: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360
           VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV
Sbjct: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360

Query: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420
           PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL
Sbjct: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420

Query: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469
           PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE
Sbjct: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469


>gi|190014617 solute carrier family 39 (zinc transporter), member 13
           isoform a [Homo sapiens]
          Length = 371

 Score =  194 bits (494), Expect = 1e-49
 Identities = 131/361 (36%), Positives = 188/361 (52%), Gaps = 58/361 (16%)

Query: 119 ESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL----LQILLS 174
           ES + G     + +  W  +L  ++++  +  F L +IP+E  +          L+ LLS
Sbjct: 52  ESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLS 111

Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS----VGLWVLSGIVAF 230
           FA GGLLG+ FLHL+P A    ++     PG      G+G  L     +GLWV++GI+ F
Sbjct: 112 FALGGLLGNVFLHLLPEAW---AYTCSASPG------GEGQSLQQQQQLGLWVIAGILTF 162

Query: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290
           L +EK                                  +KE+ +S+   K+        
Sbjct: 163 LALEKMFL------------------------------DSKEEGTSQAPNKDPTAAAAAL 192

Query: 291 GGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGL 347
            G      G    Q A E   G     ++VSGYLNL A+   NFT GLA+ ASF   + +
Sbjct: 193 NG------GHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKI 246

Query: 348 GILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEG--GA 405
           G+LTTM +LLHE+PHEVGDFAIL+++G  +  A +LQL TA+G L G   A+ T+   G 
Sbjct: 247 GLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV 306

Query: 406 VGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLI 465
           VG   A      WVLPFT+GGF+Y+A V+VLP+LL E  P +SL ++L L  G+++MVL 
Sbjct: 307 VGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLF 366

Query: 466 A 466
           +
Sbjct: 367 S 367


>gi|40255101 solute carrier family 39 (zinc transporter), member 13
           isoform b [Homo sapiens]
          Length = 364

 Score =  189 bits (480), Expect = 5e-48
 Identities = 129/359 (35%), Positives = 186/359 (51%), Gaps = 61/359 (16%)

Query: 119 ESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL----LQILLS 174
           ES + G     + +  W  +L  ++++  +  F L +IP+E  +          L+ LLS
Sbjct: 52  ESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLS 111

Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS----VGLWVLSGIVAF 230
           FA GGLLG+ FLHL+P A    ++     PG      G+G  L     +GLWV++GI+ F
Sbjct: 112 FALGGLLGNVFLHLLPEAW---AYTCSASPG------GEGQSLQQQQQLGLWVIAGILTF 162

Query: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290
           L +EK                                  +KE+ +S+   K+        
Sbjct: 163 LALEKMFL------------------------------DSKEEGTSQAPNKDPTAAAAAL 192

Query: 291 GGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGL 347
            G      G    Q A E   G     ++VSGYLNL A+   NFT GLA+ ASF   + +
Sbjct: 193 NG------GHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKI 246

Query: 348 GILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVG 407
           G+LTTM +LLHE+PHEVGDFAIL+++G  +  A +LQL TA+G L G   A+ T+     
Sbjct: 247 GLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV 306

Query: 408 SEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIA 466
            E A      WVLPFT+GGF+Y+A V+VLP+LL E  P +SL ++L L  G+++MVL +
Sbjct: 307 EETA-----AWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS 360


>gi|115430259 solute carrier family 39 (zinc transporter), member 4
           isoform 1 [Homo sapiens]
          Length = 622

 Score =  146 bits (369), Expect = 3e-35
 Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)

Query: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
           G       P ++  L     + Y   AT+LI     F L L+           +LQ  LS
Sbjct: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341

Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
            A G L GDA LHL P  L  H+H          S  G  P  +  L  +L+G+ AF + 
Sbjct: 342 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 391

Query: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
           E     +          G  GHS       SH+ G H HG         Q +  E ++ +
Sbjct: 392 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 438

Query: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
              +      V ++ P    N E  +   +LR+  Y+    D  HNF DGLA+GA+F   
Sbjct: 439 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 497

Query: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
              G+ T++ V  HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG   AL     
Sbjct: 498 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 552

Query: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
           AVG          W+L    G F+YVA   +LP +L+   P   L  LL  +GLLGG  +
Sbjct: 553 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 609

Query: 462 MVLIAHLE 469
           ++L++  E
Sbjct: 610 LLLLSLYE 617


>gi|115430255 solute carrier family 39 (zinc transporter), member 4
           isoform 2 [Homo sapiens]
          Length = 647

 Score =  146 bits (369), Expect = 3e-35
 Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)

Query: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
           G       P ++  L     + Y   AT+LI     F L L+           +LQ  LS
Sbjct: 307 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 366

Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
            A G L GDA LHL P  L  H+H          S  G  P  +  L  +L+G+ AF + 
Sbjct: 367 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 416

Query: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
           E     +          G  GHS       SH+ G H HG         Q +  E ++ +
Sbjct: 417 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 463

Query: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
              +      V ++ P    N E  +   +LR+  Y+    D  HNF DGLA+GA+F   
Sbjct: 464 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 522

Query: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
              G+ T++ V  HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG   AL     
Sbjct: 523 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 577

Query: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
           AVG          W+L    G F+YVA   +LP +L+   P   L  LL  +GLLGG  +
Sbjct: 578 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 634

Query: 462 MVLIAHLE 469
           ++L++  E
Sbjct: 635 LLLLSLYE 642


>gi|223633939 solute carrier family 39 (zinc transporter), member 12
           isoform 1 [Homo sapiens]
          Length = 691

 Score =  140 bits (352), Expect = 3e-33
 Identities = 103/350 (29%), Positives = 158/350 (45%), Gaps = 45/350 (12%)

Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
           + Y+  A  L++        L+   S    +R +LQ+ +  A G L GDA LHLIP  L 
Sbjct: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426

Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKF------------VRHVKG 242
            H     E P  GH H  +G I  + + ++ GI  F ++EK             +  V G
Sbjct: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNG 482

Query: 243 GHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVR 302
             GHSH H   +S      G G+   + + K   + +  E                 P+ 
Sbjct: 483 HVGHSH-HLALNSELSDQAGRGKSASTIQLKSPEDSQAAEM----------------PIG 525

Query: 303 PQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPH 362
              A   K    + +   + L  D  HNF DGLAIGA+F      G+ TT+ +L HE+PH
Sbjct: 526 SMTASNRKCKA-ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPH 584

Query: 363 EVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPF 422
           E+GDFA+L+ SG S K A+ +  ++++ A  G    L        S  A      W+   
Sbjct: 585 EMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTV 636

Query: 423 TAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
           TAG F+Y++ V +LPE+    +    +  LL+  GL+ G + ++L+A  E
Sbjct: 637 TAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 686


>gi|206597541 solute carrier family 39 (metal ion transporter),
           member 5 [Homo sapiens]
          Length = 540

 Score =  130 bits (326), Expect = 3e-30
 Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)

Query: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180
           AP    DL +  L + AL   +L   +P  +L L  +    PR  R LL  L + A G L
Sbjct: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257

Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236
            GDA LHL+PHA E               H+G G +    L  GL VL G+    V+E  
Sbjct: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304

Query: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293
           +   RH +G           +  TR          + +  Q++ E   +    Q+ +   
Sbjct: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360

Query: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352
             P   P   Q ++   + G D+    ++ L  D  HN TDGLAIGA+F  G   G+ TT
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417

Query: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412
           + V  HE+PHE+GDFA+L+QSG S +   RL LL+ V    G   A+L     VG  +  
Sbjct: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470

Query: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469
                WV   TAG F+YVA V +LP LLR   PL +   LL+ LGLL G  +M+ I  LE
Sbjct: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530


>gi|206597539 solute carrier family 39 (metal ion transporter),
           member 5 [Homo sapiens]
          Length = 540

 Score =  130 bits (326), Expect = 3e-30
 Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)

Query: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180
           AP    DL +  L + AL   +L   +P  +L L  +    PR  R LL  L + A G L
Sbjct: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257

Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236
            GDA LHL+PHA E               H+G G +    L  GL VL G+    V+E  
Sbjct: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304

Query: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293
           +   RH +G           +  TR          + +  Q++ E   +    Q+ +   
Sbjct: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360

Query: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352
             P   P   Q ++   + G D+    ++ L  D  HN TDGLAIGA+F  G   G+ TT
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417

Query: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412
           + V  HE+PHE+GDFA+L+QSG S +   RL LL+ V    G   A+L     VG  +  
Sbjct: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470

Query: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469
                WV   TAG F+YVA V +LP LLR   PL +   LL+ LGLL G  +M+ I  LE
Sbjct: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530


>gi|223633937 solute carrier family 39 (zinc transporter), member 12
           isoform 2 [Homo sapiens]
          Length = 654

 Score =  127 bits (318), Expect = 3e-29
 Identities = 97/339 (28%), Positives = 151/339 (44%), Gaps = 60/339 (17%)

Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
           + Y+  A  L++        L+   S    +R +LQ+ +  A G L GDA LHLIP  L 
Sbjct: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426

Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEK-FVRHVKGGHGHSHGHGHA 253
            H     E P  GH H  +G I  + + ++ GI  F ++EK F+  V             
Sbjct: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLV------------- 469

Query: 254 HSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL 313
                          S  +K+S E+ +                 + P+    A   K   
Sbjct: 470 ---------------SPNDKKSPEDSQAA---------------EMPIGSMTASNRKCKA 499

Query: 314 DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQS 373
            + +   + L  D  HNF DGLAIGA+F      G+ TT+ +L HE+PHE+GDFA+L+ S
Sbjct: 500 -ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558

Query: 374 GCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATV 433
           G S K A+ +  ++++ A  G    L        S  A      W+   TAG F+Y++ V
Sbjct: 559 GLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTVTAGMFLYLSLV 610

Query: 434 SVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
            +LPE+    +    +  LL+  GL+ G + ++L+A  E
Sbjct: 611 EMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 649


>gi|187936949 solute carrier family 39 (zinc transporter), member 10
           [Homo sapiens]
          Length = 831

 Score =  112 bits (281), Expect = 6e-25
 Identities = 121/417 (29%), Positives = 175/417 (41%), Gaps = 88/417 (21%)

Query: 85  HEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVL 144
           H    H HSH ++H      GHGH H H    + E        + DAV     ALG   L
Sbjct: 462 HSQGGHDHSHQHAH------GHGHSHGHESNKFLE--------EYDAVLKGLVALGGIYL 507

Query: 145 ISAAPFFV-LFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHA----LEPHSHH 199
           +      + +F    +    +   + Q       G  L D  L+  P +    L+P +  
Sbjct: 508 LFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLA-- 565

Query: 200 TLEQPGHGHSHSGQGPILSVGLWVLSGIVA-----FLVVE--KFVRHVKGGHGHSHGHGH 252
                G   S   +  +    L  L G        +L +E  K +      H HS G   
Sbjct: 566 -----GTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIEEEKII-----DHSHSDGLHT 615

Query: 253 AHSHT--RGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEK 310
            H H     +H H  + ++   K + +   K +               GP          
Sbjct: 616 IHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHH-----------SHGPCHS------- 657

Query: 311 RGLDLRVSGYLNLA-----ADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
            G DL+ +G  N+A      D  HNF+DGLAIGA+F  G   GI T++ V  HE+PHE+G
Sbjct: 658 -GSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716

Query: 366 DFAILVQSGCSKKQAMRLQLLTA----VGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
           DFA+L+++G + KQA+   LL+A    +G L GTA       G   + I       W+  
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV------GQYANNIT-----LWIFA 765

Query: 422 FTAGGFIYVATVSVLPELLREAS--------PL-QSLLEVLGLLGGVIMMVLIAHLE 469
            TAG F+YVA V +LPE+L            P+ Q +L+ LGLL G  +M++IA  E
Sbjct: 766 VTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 8/114 (7%)

Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
           W   + +  +IS      + L+P+  N    + LL  L++ A G + GDA LHL+PH+  
Sbjct: 407 WICGIISITVISLLSLLGVILVPI-INQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQG 465

Query: 195 PHSHHTLEQPGHGHSHSGQG-------PILSVGLWVLSGIVAFLVVEKFVRHVK 241
            H H      GHGHSH  +          +  GL  L GI    ++E  +R  K
Sbjct: 466 GHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFK 519



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 20/106 (18%)

Query: 35  HDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTH--------ESIWHGHTHDHDH----- 81
           H+DL  D   H    + ++  H HSH H H H H         S+     H  D      
Sbjct: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETV 160

Query: 82  --GHSHEDLH-HGHSHGYSHESLYHRGHGH-DHEHSHGGYGESGAP 123
                 +D H H H+H   H   +HR H H DH ++H  + +S  P
Sbjct: 161 EVSVKSDDKHMHDHNHRLRH---HHRLHHHLDHNNTHHFHNDSITP 203



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 8/62 (12%)

Query: 39  QEDFHGHSHRHSHEDFHHGHSHAHGHGH--THESIWHGHTHDHDHGHSHEDLHHGHSHGY 96
           +E    HSH       H    HA  H H   ++++   H H   H HSH      HSHG 
Sbjct: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSH------HSHGP 654

Query: 97  SH 98
            H
Sbjct: 655 CH 656



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%)

Query: 58  HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
           HSH+ G    HE   H   H+H HG +   L   H+H + H+   H  H H   HS    
Sbjct: 607 HSHSDGLHTIHEHDLHAAAHNH-HGENKTVLRK-HNHQWHHK---HSHHSHGPCHSGSDL 661

Query: 118 GESGAPGI 125
            E+G   I
Sbjct: 662 KETGIANI 669



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 45  HSHRHSHEDFHHGHSHAHGHGHTH 68
           H   HS     H H HAHGHGH+H
Sbjct: 458 HLLPHSQGGHDHSHQHAHGHGHSH 481



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 12/60 (20%)

Query: 32  DDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG 91
           D LH   + D H  +H H      HG +      H H+  WH   H H H HSH   H G
Sbjct: 611 DGLHTIHEHDLHAAAHNH------HGENKTVLRKHNHQ--WH---HKHSH-HSHGPCHSG 658



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 47  HRHSHEDFHHGHSHAHGHGHTHES 70
           H     D  H H+H HGH H HES
Sbjct: 462 HSQGGHDHSHQHAHGHGHSHGHES 485



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)

Query: 11  VAVGLLTW-ATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHE 52
           +AVG ++  A L LL    GGHD  H    +  HGH H H HE
Sbjct: 446 LAVGTMSGDALLHLLPHSQGGHDHSH----QHAHGHGHSHGHE 484



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKET 283
           +G H HSH H H+H+H   S        STK      + EKET
Sbjct: 119 EGKHFHSHNHQHSHNHL-NSENQTVTSVSTKRNHKC-DPEKET 159


>gi|55741750 solute carrier family 39 (zinc transporter), member 10
           [Homo sapiens]
          Length = 831

 Score =  112 bits (281), Expect = 6e-25
 Identities = 121/417 (29%), Positives = 175/417 (41%), Gaps = 88/417 (21%)

Query: 85  HEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVL 144
           H    H HSH ++H      GHGH H H    + E        + DAV     ALG   L
Sbjct: 462 HSQGGHDHSHQHAH------GHGHSHGHESNKFLE--------EYDAVLKGLVALGGIYL 507

Query: 145 ISAAPFFV-LFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHA----LEPHSHH 199
           +      + +F    +    +   + Q       G  L D  L+  P +    L+P +  
Sbjct: 508 LFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLA-- 565

Query: 200 TLEQPGHGHSHSGQGPILSVGLWVLSGIVA-----FLVVE--KFVRHVKGGHGHSHGHGH 252
                G   S   +  +    L  L G        +L +E  K +      H HS G   
Sbjct: 566 -----GTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIEEEKII-----DHSHSDGLHT 615

Query: 253 AHSHT--RGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEK 310
            H H     +H H  + ++   K + +   K +               GP          
Sbjct: 616 IHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHH-----------SHGPCHS------- 657

Query: 311 RGLDLRVSGYLNLA-----ADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
            G DL+ +G  N+A      D  HNF+DGLAIGA+F  G   GI T++ V  HE+PHE+G
Sbjct: 658 -GSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716

Query: 366 DFAILVQSGCSKKQAMRLQLLTA----VGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
           DFA+L+++G + KQA+   LL+A    +G L GTA       G   + I       W+  
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV------GQYANNIT-----LWIFA 765

Query: 422 FTAGGFIYVATVSVLPELLREAS--------PL-QSLLEVLGLLGGVIMMVLIAHLE 469
            TAG F+YVA V +LPE+L            P+ Q +L+ LGLL G  +M++IA  E
Sbjct: 766 VTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 8/114 (7%)

Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
           W   + +  +IS      + L+P+  N    + LL  L++ A G + GDA LHL+PH+  
Sbjct: 407 WICGIISITVISLLSLLGVILVPI-INQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQG 465

Query: 195 PHSHHTLEQPGHGHSHSGQG-------PILSVGLWVLSGIVAFLVVEKFVRHVK 241
            H H      GHGHSH  +          +  GL  L GI    ++E  +R  K
Sbjct: 466 GHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFK 519



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 20/106 (18%)

Query: 35  HDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTH--------ESIWHGHTHDHDH----- 81
           H+DL  D   H    + ++  H HSH H H H H         S+     H  D      
Sbjct: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETV 160

Query: 82  --GHSHEDLH-HGHSHGYSHESLYHRGHGH-DHEHSHGGYGESGAP 123
                 +D H H H+H   H   +HR H H DH ++H  + +S  P
Sbjct: 161 EVSVKSDDKHMHDHNHRLRH---HHRLHHHLDHNNTHHFHNDSITP 203



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 8/62 (12%)

Query: 39  QEDFHGHSHRHSHEDFHHGHSHAHGHGH--THESIWHGHTHDHDHGHSHEDLHHGHSHGY 96
           +E    HSH       H    HA  H H   ++++   H H   H HSH      HSHG 
Sbjct: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSH------HSHGP 654

Query: 97  SH 98
            H
Sbjct: 655 CH 656



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%)

Query: 58  HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
           HSH+ G    HE   H   H+H HG +   L   H+H + H+   H  H H   HS    
Sbjct: 607 HSHSDGLHTIHEHDLHAAAHNH-HGENKTVLRK-HNHQWHHK---HSHHSHGPCHSGSDL 661

Query: 118 GESGAPGI 125
            E+G   I
Sbjct: 662 KETGIANI 669



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 45  HSHRHSHEDFHHGHSHAHGHGHTH 68
           H   HS     H H HAHGHGH+H
Sbjct: 458 HLLPHSQGGHDHSHQHAHGHGHSH 481



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 12/60 (20%)

Query: 32  DDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG 91
           D LH   + D H  +H H      HG +      H H+  WH   H H H HSH   H G
Sbjct: 611 DGLHTIHEHDLHAAAHNH------HGENKTVLRKHNHQ--WH---HKHSH-HSHGPCHSG 658



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 47  HRHSHEDFHHGHSHAHGHGHTHES 70
           H     D  H H+H HGH H HES
Sbjct: 462 HSQGGHDHSHQHAHGHGHSHGHES 485



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)

Query: 11  VAVGLLTW-ATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHE 52
           +AVG ++  A L LL    GGHD  H    +  HGH H H HE
Sbjct: 446 LAVGTMSGDALLHLLPHSQGGHDHSH----QHAHGHGHSHGHE 484



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKET 283
           +G H HSH H H+H+H   S        STK      + EKET
Sbjct: 119 EGKHFHSHNHQHSHNHL-NSENQTVTSVSTKRNHKC-DPEKET 159


>gi|205830424 solute carrier family 39 (zinc transporter), member 14
           isoform a [Homo sapiens]
          Length = 492

 Score =  102 bits (253), Expect = 1e-21
 Identities = 107/386 (27%), Positives = 160/386 (41%), Gaps = 66/386 (17%)

Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
           + E+      E G P       AV +W Y L    +IS        ++P    +  ++ L
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186

Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
           L   ++ A G L  +A   LIP A                   G  P+    +S    V 
Sbjct: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228

Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
            G   F   EK ++ + K  + H HGH H  S +  S     QE    EK          
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286

Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
               SSE + K     +K   GS   +D     Q+A    +G+   D+    ++   +D 
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345

Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
            HNF DGLAIGASF      GI T++ +L  E PHE+GDF IL+ +G S +QA+    L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405

Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
           A     G A  +L      GS  +      W+     G F+Y++   + PE+        
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456

Query: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
           R+ S L   +++ LGLL G  +MV++
Sbjct: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482


>gi|190360568 solute carrier family 39 (zinc transporter), member 14
           isoform a [Homo sapiens]
          Length = 492

 Score =  102 bits (253), Expect = 1e-21
 Identities = 107/386 (27%), Positives = 160/386 (41%), Gaps = 66/386 (17%)

Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
           + E+      E G P       AV +W Y L    +IS        ++P    +  ++ L
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186

Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
           L   ++ A G L  +A   LIP A                   G  P+    +S    V 
Sbjct: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228

Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
            G   F   EK ++ + K  + H HGH H  S +  S     QE    EK          
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286

Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
               SSE + K     +K   GS   +D     Q+A    +G+   D+    ++   +D 
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345

Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
            HNF DGLAIGASF      GI T++ +L  E PHE+GDF IL+ +G S +QA+    L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405

Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
           A     G A  +L      GS  +      W+     G F+Y++   + PE+        
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456

Query: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
           R+ S L   +++ LGLL G  +MV++
Sbjct: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482


>gi|190358541 solute carrier family 39 (zinc transporter), member 14
           isoform b [Homo sapiens]
          Length = 492

 Score =  100 bits (249), Expect = 3e-21
 Identities = 106/386 (27%), Positives = 162/386 (41%), Gaps = 66/386 (17%)

Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
           + E+      E G P       AV +W +   +  LI+ A    + ++P    +   R +
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSR-V 186

Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
           L   ++ + G LL +A   LIP A                   G  P+    +S    V 
Sbjct: 187 LTYFIALSIGTLLSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228

Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
            G   F   EK ++ + K  + H HGH H  S +  S     QE    EK          
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286

Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
               SSE + K     +K   GS   +D     Q+A    +G+   D+    ++   +D 
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345

Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
            HNF DGLAIGASF      GI T++ +L  E PHE+GDF IL+ +G S +QA+    L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405

Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
           A     G A  +L      GS  +      W+     G F+Y++   + PE+        
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456

Query: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
           R+ S L   +++ LGLL G  +MV++
Sbjct: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482


>gi|153252201 solute carrier family 39 (zinc transporter), member 6
           isoform 1 [Homo sapiens]
          Length = 755

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 58/171 (33%), Positives = 92/171 (53%), Gaps = 14/171 (8%)

Query: 306 AEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
           + EE +   +    ++ +  D  HNF+DGLAIGA+F  G   G+ T++ V  HE+PHE+G
Sbjct: 583 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 642

Query: 366 DFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAG 425
           DFA+L+++G + KQA+    L+A+ A  G A  +     A    +       W+   TAG
Sbjct: 643 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSM-------WIFALTAG 695

Query: 426 GFIYVATVSVLPELLREASPLQS-------LLEVLGLLGGVIMMVLIAHLE 469
            F+YVA V ++PE+L   +            L+  G+L G  +M+LI+  E
Sbjct: 696 LFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 746



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
           W     A  +IS      + L+P+  N    + LL  L++ A G L GDAFLHL+PH+  
Sbjct: 325 WVGGFIAISIISFLSLLGVILVPL-MNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHA 383

Query: 195 PHSH-HTLEQPGHGHSHSGQGPILS 218
            H H H+ E+P        +GP+ S
Sbjct: 384 SHHHSHSHEEPA---MEMKRGPLFS 405



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)

Query: 66  HTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGI 125
           H H    H H  DH+H HS  + H  H H   HE  +H  H H   H+H   G++    +
Sbjct: 91  HIHHD--HDHHSDHEH-HSDHERHSDHEHHSDHE--HHSDHDHHSHHNHAASGKNKRKAL 145

Query: 126 KQDLDA 131
             D D+
Sbjct: 146 CPDHDS 151



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 49  HSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGH 108
           H H D  H   H H   H   S  H H  DH+H HS  D H  H+H  S ++   +    
Sbjct: 91  HIHHDHDHHSDHEHHSDHERHSD-HEHHSDHEH-HSDHDHHSHHNHAASGKN-KRKALCP 147

Query: 109 DHEHSHGGYGESGAPG 124
           DH+    G     + G
Sbjct: 148 DHDSDSSGKDPRNSQG 163



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 34  LHDDLQEDFHGHSHRHSH-EDFHHGHSHAHGHGHTHESIWHG-----HTHDHDHGHSHED 87
           L  D QE  H  S + +  E+     +HAH     +E +  G     H+H HD     +D
Sbjct: 494 LRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553

Query: 88  LHHGHSHGYSHESLYHRGHGHDHEHSH 114
           L H H H Y H  L+H  H + H HSH
Sbjct: 554 LIH-HHHDY-HHILHHHHHQNHHPHSH 578



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 3/51 (5%)

Query: 58  HSHAHGH-GHTHESIWHGHTHDHDHGHSHEDLHHGHSHG--YSHESLYHRG 105
           HSH H   G + + I H H + H   H H   HH HSH   YS E L   G
Sbjct: 541 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAG 591



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 15/43 (34%), Positives = 16/43 (37%), Gaps = 2/43 (4%)

Query: 43  HGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH 85
           H H H   HE  HH     H     H    H   HDH   H+H
Sbjct: 94  HDHDHHSDHE--HHSDHERHSDHEHHSDHEHHSDHDHHSHHNH 134



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 11/89 (12%)

Query: 34  LHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL----- 88
           +H     D H     HS  + H  H H   H H  +   H H   H+H  S ++      
Sbjct: 90  IHIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSD---HDHHSHHNHAASGKNKRKALC 146

Query: 89  --HHGHSHGYSHESLYHRGHGHDHEHSHG 115
             H   S G    +   +G  H  EH+ G
Sbjct: 147 PDHDSDSSGKDPRNSQGKG-AHRPEHASG 174



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)

Query: 31  HDDLHDDL-QEDFHGHSHRHSHEDFHHGHSHAHGHGHTH 68
           H   HD L Q D   H H   H   HH H H + H H+H
Sbjct: 541 HSHFHDTLGQSDDLIHHHHDYHHILHH-HHHQNHHPHSH 578


>gi|205830426 solute carrier family 39 (zinc transporter), member 14
           isoform c [Homo sapiens]
          Length = 481

 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 95/349 (27%), Positives = 141/349 (40%), Gaps = 58/349 (16%)

Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
           + E+      E G P       AV +W Y L    +IS        ++P    +  ++ L
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186

Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
           L   ++ A G L  +A   LIP A                   G  P+    +S    V 
Sbjct: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228

Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
            G   F   EK ++ + K  + H HGH H  S +  S     QE    EK          
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286

Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
               SSE + K     +K   GS   +D     Q+A    +G+   D+    ++   +D 
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345

Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
            HNF DGLAIGASF      GI T++ +L  E PHE+GDF IL+ +G S +QA+    L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405

Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVL 436
           A     G A  +L      GS  +      W+     G F+Y++   ++
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMM 445


>gi|153252214 solute carrier family 39 (zinc transporter), member 6
           isoform 2 [Homo sapiens]
          Length = 433

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 47/131 (35%), Positives = 74/131 (56%), Gaps = 7/131 (5%)

Query: 306 AEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
           + EE +   +    ++ +  D  HNF+DGLAIGA+F  G   G+ T++ V  HE+PHE+G
Sbjct: 308 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 367

Query: 366 DFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAG 425
           DFA+L+++G + KQA+    L+A+ A  G A  +     A    +       W+   TAG
Sbjct: 368 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSM-------WIFALTAG 420

Query: 426 GFIYVATVSVL 436
            F+YVA V ++
Sbjct: 421 LFMYVALVDMV 431



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
           W     A  +IS      + L+P+  N    + LL  L++ A G L GDAFLHL+PH+  
Sbjct: 50  WVGGFIAISIISFLSLLGVILVPL-MNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHA 108

Query: 195 PHSH-HTLEQPGHGHSHSGQGPILS 218
            H H H+ E+P        +GP+ S
Sbjct: 109 SHHHSHSHEEPA---MEMKRGPLFS 130



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 34  LHDDLQEDFHGHSHRHSH-EDFHHGHSHAHGHGHTHESIWHG-----HTHDHDHGHSHED 87
           L  D QE  H  S + +  E+     +HAH     +E +  G     H+H HD     +D
Sbjct: 219 LRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 278

Query: 88  LHHGHSHGYSHESLYHRGHGHDHEHSH 114
           L H H H Y H  L+H  H + H HSH
Sbjct: 279 LIH-HHHDY-HHILHHHHHQNHHPHSH 303



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 3/51 (5%)

Query: 58  HSHAHGH-GHTHESIWHGHTHDHDHGHSHEDLHHGHSHG--YSHESLYHRG 105
           HSH H   G + + I H H + H   H H   HH HSH   YS E L   G
Sbjct: 266 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAG 316



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)

Query: 31  HDDLHDDL-QEDFHGHSHRHSHEDFHHGHSHAHGHGHTH 68
           H   HD L Q D   H H   H   HH H H + H H+H
Sbjct: 266 HSHFHDTLGQSDDLIHHHHDYHHILHH-HHHQNHHPHSH 303


>gi|24586665 solute carrier family 39 (zinc transporter), member 8
           isoform a [Homo sapiens]
          Length = 460

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)

Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
           +W Y   +  +I+ A    L L P+   S     +L   +  A G L  +A   LIP A 
Sbjct: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186

Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
             +P     +E+                 + V  G       E+ ++ +   +G +   G
Sbjct: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227

Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
           H H    G+   G QE++ + K           +     E  G       S V  +DG  
Sbjct: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284

Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
            P +    K  +  ++    ++    D  HNF DGLAIGAS       G+ T++ +L  E
Sbjct: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344

Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
            PHE+GDF IL+ +G S +QA+    L+A     G A  +L     VG+  A    P  +
Sbjct: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395

Query: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
                G F+Y++   + PE   +LRE    +       +++  G+L G   ++LI
Sbjct: 396 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 450


>gi|205830407 solute carrier family 39 (zinc transporter), member 8
           isoform c [Homo sapiens]
          Length = 393

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)

Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
           +W Y   +  +I+ A    L L P+   S     +L   +  A G L  +A   LIP A 
Sbjct: 61  VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 119

Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
             +P     +E+                 + V  G       E+ ++ +   +G +   G
Sbjct: 120 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 160

Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
           H H    G+   G QE++ + K           +     E  G       S V  +DG  
Sbjct: 161 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 217

Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
            P +    K  +  ++    ++    D  HNF DGLAIGAS       G+ T++ +L  E
Sbjct: 218 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 277

Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
            PHE+GDF IL+ +G S +QA+    L+A     G A  +L     VG+  A    P  +
Sbjct: 278 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 328

Query: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
                G F+Y++   + PE   +LRE    +       +++  G+L G   ++LI
Sbjct: 329 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 383


>gi|205830403 solute carrier family 39 (zinc transporter), member 8
           isoform a [Homo sapiens]
          Length = 460

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)

Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
           +W Y   +  +I+ A    L L P+   S     +L   +  A G L  +A   LIP A 
Sbjct: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186

Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
             +P     +E+                 + V  G       E+ ++ +   +G +   G
Sbjct: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227

Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
           H H    G+   G QE++ + K           +     E  G       S V  +DG  
Sbjct: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284

Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
            P +    K  +  ++    ++    D  HNF DGLAIGAS       G+ T++ +L  E
Sbjct: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344

Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
            PHE+GDF IL+ +G S +QA+    L+A     G A  +L     VG+  A    P  +
Sbjct: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395

Query: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
                G F+Y++   + PE   +LRE    +       +++  G+L G   ++LI
Sbjct: 396 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 450


>gi|205830405 solute carrier family 39 (zinc transporter), member 8
           isoform b [Homo sapiens]
          Length = 444

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 81/320 (25%), Positives = 129/320 (40%), Gaps = 46/320 (14%)

Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
           +W Y   +  +I+ A    L L P+   S     +L   +  A G L  +A   LIP A 
Sbjct: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186

Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
             +P     +E+                 + V  G       E+ ++ +   +G +   G
Sbjct: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227

Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
           H H    G+   G QE++ + K           +     E  G       S V  +DG  
Sbjct: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284

Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
            P +    K  +  ++    ++    D  HNF DGLAIGAS       G+ T++ +L  E
Sbjct: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344

Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
            PHE+GDF IL+ +G S +QA+    L+A     G A  +L     VG+  A    P  +
Sbjct: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395

Query: 420 LPFTAGGFIYVATVSVLPEL 439
                G F+Y++   + PE+
Sbjct: 396 FALAGGMFLYISLADMFPEM 415


>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
          Length = 525

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 36/96 (37%), Positives = 39/96 (40%), Gaps = 12/96 (12%)

Query: 29  GGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL 88
           G     H++   D H H H HSHE   HGH H H H        H H HD    H H   
Sbjct: 336 GAQRHSHNNNSSDLHPHKH-HSHEQHPHGH-HPHAH--------HPHEHDTHRQHPHGHH 385

Query: 89  HHGHSHGYSHESLYHRGHG-HDHEHSHGGYGESGAP 123
            HGH H + H    H  HG H H H    YG    P
Sbjct: 386 PHGH-HPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP 420



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 30/84 (35%), Positives = 33/84 (39%), Gaps = 16/84 (19%)

Query: 31  HDDLHDDLQEDFHGHSHR--HSHEDFHHGHSHAHGHGHTHESIWHGHTHD-HDHG----H 83
           H   HD  ++  HGH     H H    HGH H HGH        H H HD  D+G     
Sbjct: 370 HPHEHDTHRQHPHGHHPHGHHPHGHHPHGH-HPHGH--------HPHCHDFQDYGPCDPP 420

Query: 84  SHEDLHHGHSHGYSHESLYHRGHG 107
            H   H  H HG     L  RG G
Sbjct: 421 PHNQGHCCHGHGPPPGHLRRRGPG 444



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 20/71 (28%)

Query: 193 LEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
           L PH HH+ EQ  HGH      P                   +   H +  HGH H HGH
Sbjct: 349 LHPHKHHSHEQHPHGHHPHAHHP------------------HEHDTHRQHPHGH-HPHGH 389

Query: 253 AHSHTRGSHGH 263
            H H    HGH
Sbjct: 390 -HPHGHHPHGH 399



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 27/88 (30%), Positives = 28/88 (31%), Gaps = 34/88 (38%)

Query: 190 PHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHG 249
           PHA  PH H T  Q  HGH   G  P                       H  G H H H 
Sbjct: 366 PHAHHPHEHDTHRQHPHGHHPHGHHP--------------------HGHHPHGHHPHGH- 404

Query: 250 HGHAHS-----------HTRG--SHGHG 264
           H H H            H +G   HGHG
Sbjct: 405 HPHCHDFQDYGPCDPPPHNQGHCCHGHG 432



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 22/73 (30%), Positives = 22/73 (30%), Gaps = 25/73 (34%)

Query: 191 HALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGH 250
           H   PH HH      H H    Q P                       H    HGH H H
Sbjct: 357 HEQHPHGHHPHAHHPHEHDTHRQHP-----------------------HGHHPHGH-HPH 392

Query: 251 GHAHSHTRGSHGH 263
           GH H H    HGH
Sbjct: 393 GH-HPHGHHPHGH 404


>gi|156231037 kininogen 1 isoform 1 [Homo sapiens]
          Length = 644

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 19/96 (19%)

Query: 31  HDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH----- 85
           HD  H+  ++   GH H+H  +    GH H  GHG     + HGH   H  GH H     
Sbjct: 429 HDWGHEKQRKHNLGHGHKHERDQ---GHGHQRGHG-----LGHGHEQQHGLGHGHKFKLD 480

Query: 86  EDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESG 121
           +DL H   H   H      GH H H H HG +   G
Sbjct: 481 DDLEHQGGHVLDH------GHKHKHGHGHGKHKNKG 510



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 20/79 (25%)

Query: 57  GHSHAHGHGHTHE---SIWHGHTHDHDHGHSHEDLH---HGH--SHGYSH-------ESL 101
           GH+  H  GH  +   ++ HGH H+ D GH H+  H   HGH   HG  H       + L
Sbjct: 424 GHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDL 483

Query: 102 YHRG-----HGHDHEHSHG 115
            H+G     HGH H+H HG
Sbjct: 484 EHQGGHVLDHGHKHKHGHG 502



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 8/52 (15%)

Query: 74  GHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGH------GHDHEHSHG-GYG 118
           GHT  HD GH  +  H+   HG+ HE     GH      GH HE  HG G+G
Sbjct: 424 GHTRRHDWGHEKQRKHN-LGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHG 474



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 32/112 (28%), Positives = 42/112 (37%), Gaps = 16/112 (14%)

Query: 196 HSHHTLEQPGHGHSHS---GQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
           H H      GHGH      G G     GL    G      ++  + H +GGH   HGH H
Sbjct: 443 HGHKHERDQGHGHQRGHGLGHGHEQQHGL----GHGHKFKLDDDLEH-QGGHVLDHGHKH 497

Query: 253 AHSHTRGSH-----GHGRQERSTKEKQSSEEEEKETRGVQ---KRRGGSTVP 296
            H H  G H      +G+      E  +S  E+  T   Q   K  G + +P
Sbjct: 498 KHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTPIP 549



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 9/46 (19%)

Query: 30  GHDDLHDDLQEDFHGHSHRHSHED---------FHHGHSHAHGHGH 66
           GH   H   Q+   GH H+   +D           HGH H HGHGH
Sbjct: 458 GHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH 503



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 13/27 (48%), Positives = 14/27 (51%), Gaps = 3/27 (11%)

Query: 243 GHGHSHGHGHAHSHTRG---SHGHGRQ 266
           GHGH H     H H RG    HGH +Q
Sbjct: 442 GHGHKHERDQGHGHQRGHGLGHGHEQQ 468


>gi|222080086 zinc transporter like 2 [Homo sapiens]
          Length = 376

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 15/102 (14%)

Query: 55  HHGHSHAHGHGHTH-ESIWHG---HTHDH-DHGHSHEDLHHGHSHGYSHESLYHRGHGHD 109
           H GH H+HG GH H  S+++G     H H DH HSHE + HG +H + H       HGH 
Sbjct: 161 HGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHE-VKHGAAHSHDH------AHGHG 213

Query: 110 HEHSHGGYGESGAPG-IKQDLDAVTLWAYA--LGATVLISAA 148
           H HSH G       G  +Q L  V L   A  LG+  +I++A
Sbjct: 214 HFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASA 255



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 9/70 (12%)

Query: 242 GGHGHSHGHGHAHSHT------RGSHGHGRQERSTKEKQSSEEEEKETRG---VQKRRGG 292
           GGHGHSHG GH HSH+        +HGH     S + K  +        G        G 
Sbjct: 162 GGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGP 221

Query: 293 STVPKDGPVR 302
           S     GP R
Sbjct: 222 SLKETTGPSR 231



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 16/109 (14%)

Query: 166 RSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLS 225
           R LL  +L F    L+G   + +  H    HSH +    GHGHSHS    + +  L    
Sbjct: 140 RLLLVSILGFVVN-LIG---IFVFKHGGHGHSHGS----GHGHSHS----LFNGALDQAH 187

Query: 226 GIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ 274
           G V           VK G  HSH H H H H     G   +E +   +Q
Sbjct: 188 GHVDHC----HSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQ 232


>gi|40255009 zinc transporter like 2 [Homo sapiens]
          Length = 376

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 15/102 (14%)

Query: 55  HHGHSHAHGHGHTH-ESIWHG---HTHDH-DHGHSHEDLHHGHSHGYSHESLYHRGHGHD 109
           H GH H+HG GH H  S+++G     H H DH HSHE + HG +H + H       HGH 
Sbjct: 161 HGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHE-VKHGAAHSHDH------AHGHG 213

Query: 110 HEHSHGGYGESGAPG-IKQDLDAVTLWAYA--LGATVLISAA 148
           H HSH G       G  +Q L  V L   A  LG+  +I++A
Sbjct: 214 HFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASA 255



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 9/70 (12%)

Query: 242 GGHGHSHGHGHAHSHT------RGSHGHGRQERSTKEKQSSEEEEKETRG---VQKRRGG 292
           GGHGHSHG GH HSH+        +HGH     S + K  +        G        G 
Sbjct: 162 GGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGP 221

Query: 293 STVPKDGPVR 302
           S     GP R
Sbjct: 222 SLKETTGPSR 231



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 16/109 (14%)

Query: 166 RSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLS 225
           R LL  +L F    L+G   + +  H    HSH +    GHGHSHS    + +  L    
Sbjct: 140 RLLLVSILGFVVN-LIG---IFVFKHGGHGHSHGS----GHGHSHS----LFNGALDQAH 187

Query: 226 GIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ 274
           G V           VK G  HSH H H H H     G   +E +   +Q
Sbjct: 188 GHVDHC----HSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQ 232


>gi|40254928 solute carrier family 39 (zinc transporter), member 9
           [Homo sapiens]
          Length = 307

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 63/290 (21%), Positives = 114/290 (39%), Gaps = 43/290 (14%)

Query: 151 FVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSH 210
           +V  +IP+  N    R  L+++    +G L G A   ++P  +       LE   H  S 
Sbjct: 19  YVAGIIPLAVNFSEER--LKLVTVLGAGLLCGTALAVIVPEGVHALYEDILEGKHHQASE 76

Query: 211 SGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERST 270
           +             + I +    EK V H    H HSH H   H++   S   G      
Sbjct: 77  TH------------NVIASDKAAEKSVVHE---HEHSHDHTQLHAYIGVSLVLGFVFMLL 121

Query: 271 KEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHN 330
            ++  +                        V   +  E  R  + +++  L L   + H 
Sbjct: 122 VDQIGNSH----------------------VHSTDDPEAARSSNSKITTTLGL---VVHA 156

Query: 331 FTDGLAIGASFRGGR-GLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAV 389
             DG+A+GA+    +  + ++  + ++LH+ P   G  + L+ +G  + +  +  L+ A+
Sbjct: 157 AADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFAL 216

Query: 390 GALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL 439
            A   +    L    +    ++     G  + F+AG F+YVATV VLPE+
Sbjct: 217 AAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV 266



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 12/38 (31%), Positives = 17/38 (44%)

Query: 52  EDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLH 89
           E  HH  S  H    + ++      H+H+H H H  LH
Sbjct: 68  EGKHHQASETHNVIASDKAAEKSVVHEHEHSHDHTQLH 105


>gi|59938776 cAMP responsive element binding protein 5 isoform delta
           [Homo sapiens]
          Length = 369

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 8/87 (9%)

Query: 20  TLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDF--HHGHSHAHGHG--HTHESIWHGH 75
           T+G ++  +G   D         H HSH H H+    HH + H H H   H H    H  
Sbjct: 115 TMGHMMEMMGSRQDQ----TPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQ 170

Query: 76  THDHDHGHSHEDLHHGHSHGYSHESLY 102
            H H H HSH   H  H     H  L+
Sbjct: 171 NHPHHHSHSHLHAHPAHHQTSPHPPLH 197



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 58  HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
           H H H H H H+++   H + H H H     HH H   + H+  +   H H H H+H  +
Sbjct: 132 HHHMHSHPHQHQTLPPHHPYPHQHQH---PAHHPHPQPH-HQQNHPHHHSHSHLHAHPAH 187

Query: 118 GES 120
            ++
Sbjct: 188 HQT 190



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)

Query: 56  HGHSHAHGHGHTHESIWHGHTHDHDH--GHSHEDLHH--GHSHGYSHESLY-HRGHGHDH 110
           H H H+H H H      H + H H H   H H   HH   H H +SH  L+ H  H    
Sbjct: 132 HHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTS 191

Query: 111 EHS--HGGYGESGAPGIKQ 127
            H   H G     +P  +Q
Sbjct: 192 PHPPLHTGNQAQVSPATQQ 210



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 10/76 (13%)

Query: 49  HSHEDFHHGHSHAHGH-----GHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY- 102
           H      +G+ +  GH     G   +   H H H H H H     HH + H + H + + 
Sbjct: 103 HHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 162

Query: 103 ----HRGHGHDHEHSH 114
               H    H H HSH
Sbjct: 163 HPQPHHQQNHPHHHSH 178



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/44 (36%), Positives = 17/44 (38%), Gaps = 2/44 (4%)

Query: 43  HGHSHRHSHEDFHH--GHSHAHGHGHTHESIWHGHTHDHDHGHS 84
           H H   H H   HH   H H H H H H    H  T  H   H+
Sbjct: 155 HQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHT 198



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 20/69 (28%)

Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAH 254
           PH H TL  P H + H  Q P                       H +  H  +H H H+H
Sbjct: 139 PHQHQTLP-PHHPYPHQHQHPAHHP-------------------HPQPHHQQNHPHHHSH 178

Query: 255 SHTRGSHGH 263
           SH      H
Sbjct: 179 SHLHAHPAH 187


>gi|59938774 cAMP responsive element binding protein 5 isoform beta
           [Homo sapiens]
          Length = 501

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 8/87 (9%)

Query: 20  TLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDF--HHGHSHAHGHG--HTHESIWHGH 75
           T+G ++  +G   D         H HSH H H+    HH + H H H   H H    H  
Sbjct: 247 TMGHMMEMMGSRQDQ----TPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQ 302

Query: 76  THDHDHGHSHEDLHHGHSHGYSHESLY 102
            H H H HSH   H  H     H  L+
Sbjct: 303 NHPHHHSHSHLHAHPAHHQTSPHPPLH 329



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 58  HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
           H H H H H H+++   H + H H H     HH H   + H+  +   H H H H+H  +
Sbjct: 264 HHHMHSHPHQHQTLPPHHPYPHQHQH---PAHHPHPQPH-HQQNHPHHHSHSHLHAHPAH 319

Query: 118 GES 120
            ++
Sbjct: 320 HQT 322



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)

Query: 56  HGHSHAHGHGHTHESIWHGHTHDHDH--GHSHEDLHH--GHSHGYSHESLY-HRGHGHDH 110
           H H H+H H H      H + H H H   H H   HH   H H +SH  L+ H  H    
Sbjct: 264 HHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTS 323

Query: 111 EHS--HGGYGESGAPGIKQ 127
            H   H G     +P  +Q
Sbjct: 324 PHPPLHTGNQAQVSPATQQ 342



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 10/76 (13%)

Query: 49  HSHEDFHHGHSHAHGH-----GHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY- 102
           H      +G+ +  GH     G   +   H H H H H H     HH + H + H + + 
Sbjct: 235 HHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 294

Query: 103 ----HRGHGHDHEHSH 114
               H    H H HSH
Sbjct: 295 HPQPHHQQNHPHHHSH 310



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/44 (36%), Positives = 17/44 (38%), Gaps = 2/44 (4%)

Query: 43  HGHSHRHSHEDFHH--GHSHAHGHGHTHESIWHGHTHDHDHGHS 84
           H H   H H   HH   H H H H H H    H  T  H   H+
Sbjct: 287 HQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHT 330



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 20/69 (28%)

Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAH 254
           PH H TL  P H + H  Q P                       H +  H  +H H H+H
Sbjct: 271 PHQHQTLP-PHHPYPHQHQHPAHHP-------------------HPQPHHQQNHPHHHSH 310

Query: 255 SHTRGSHGH 263
           SH      H
Sbjct: 311 SHLHAHPAH 319


>gi|59938772 cAMP responsive element binding protein 5 isoform gamma
           [Homo sapiens]
          Length = 475

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 8/87 (9%)

Query: 20  TLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDF--HHGHSHAHGHG--HTHESIWHGH 75
           T+G ++  +G   D         H HSH H H+    HH + H H H   H H    H  
Sbjct: 221 TMGHMMEMMGSRQDQ----TPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQ 276

Query: 76  THDHDHGHSHEDLHHGHSHGYSHESLY 102
            H H H HSH   H  H     H  L+
Sbjct: 277 NHPHHHSHSHLHAHPAHHQTSPHPPLH 303



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 58  HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
           H H H H H H+++   H + H H H     HH H   + H+  +   H H H H+H  +
Sbjct: 238 HHHMHSHPHQHQTLPPHHPYPHQHQH---PAHHPHPQPH-HQQNHPHHHSHSHLHAHPAH 293

Query: 118 GES 120
            ++
Sbjct: 294 HQT 296



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)

Query: 56  HGHSHAHGHGHTHESIWHGHTHDHDH--GHSHEDLHH--GHSHGYSHESLY-HRGHGHDH 110
           H H H+H H H      H + H H H   H H   HH   H H +SH  L+ H  H    
Sbjct: 238 HHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTS 297

Query: 111 EHS--HGGYGESGAPGIKQ 127
            H   H G     +P  +Q
Sbjct: 298 PHPPLHTGNQAQVSPATQQ 316



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 10/76 (13%)

Query: 49  HSHEDFHHGHSHAHGH-----GHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY- 102
           H      +G+ +  GH     G   +   H H H H H H     HH + H + H + + 
Sbjct: 209 HHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 268

Query: 103 ----HRGHGHDHEHSH 114
               H    H H HSH
Sbjct: 269 HPQPHHQQNHPHHHSH 284



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/44 (36%), Positives = 17/44 (38%), Gaps = 2/44 (4%)

Query: 43  HGHSHRHSHEDFHH--GHSHAHGHGHTHESIWHGHTHDHDHGHS 84
           H H   H H   HH   H H H H H H    H  T  H   H+
Sbjct: 261 HQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHT 304



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 20/69 (28%)

Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAH 254
           PH H TL  P H + H  Q P                       H +  H  +H H H+H
Sbjct: 245 PHQHQTLP-PHHPYPHQHQHPAHHP-------------------HPQPHHQQNHPHHHSH 284

Query: 255 SHTRGSHGH 263
           SH      H
Sbjct: 285 SHLHAHPAH 293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,891,453
Number of Sequences: 37866
Number of extensions: 1079700
Number of successful extensions: 10970
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 6510
Number of HSP's gapped (non-prelim): 2354
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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