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Search of human proteins with 117553608
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
(469 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 979 0.0
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 979 0.0
gi|190014617 solute carrier family 39 (zinc transporter), member... 194 1e-49
gi|40255101 solute carrier family 39 (zinc transporter), member ... 189 5e-48
gi|115430259 solute carrier family 39 (zinc transporter), member... 146 3e-35
gi|115430255 solute carrier family 39 (zinc transporter), member... 146 3e-35
gi|223633939 solute carrier family 39 (zinc transporter), member... 140 3e-33
gi|206597541 solute carrier family 39 (metal ion transporter), m... 130 3e-30
gi|206597539 solute carrier family 39 (metal ion transporter), m... 130 3e-30
gi|223633937 solute carrier family 39 (zinc transporter), member... 127 3e-29
gi|187936949 solute carrier family 39 (zinc transporter), member... 112 6e-25
gi|55741750 solute carrier family 39 (zinc transporter), member ... 112 6e-25
gi|205830424 solute carrier family 39 (zinc transporter), member... 102 1e-21
gi|190360568 solute carrier family 39 (zinc transporter), member... 102 1e-21
gi|190358541 solute carrier family 39 (zinc transporter), member... 100 3e-21
gi|153252201 solute carrier family 39 (zinc transporter), member... 95 1e-19
gi|205830426 solute carrier family 39 (zinc transporter), member... 93 5e-19
gi|153252214 solute carrier family 39 (zinc transporter), member... 86 6e-17
gi|24586665 solute carrier family 39 (zinc transporter), member ... 85 2e-16
gi|205830407 solute carrier family 39 (zinc transporter), member... 85 2e-16
gi|205830403 solute carrier family 39 (zinc transporter), member... 85 2e-16
gi|205830405 solute carrier family 39 (zinc transporter), member... 84 2e-16
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 61 2e-09
gi|156231037 kininogen 1 isoform 1 [Homo sapiens] 61 2e-09
gi|222080086 zinc transporter like 2 [Homo sapiens] 60 4e-09
gi|40255009 zinc transporter like 2 [Homo sapiens] 60 4e-09
gi|40254928 solute carrier family 39 (zinc transporter), member ... 52 2e-06
gi|59938776 cAMP responsive element binding protein 5 isoform de... 52 2e-06
gi|59938774 cAMP responsive element binding protein 5 isoform be... 52 2e-06
gi|59938772 cAMP responsive element binding protein 5 isoform ga... 52 2e-06
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 979 bits (2530), Expect = 0.0
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60
MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH
Sbjct: 1 MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60
Query: 61 AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120
AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES
Sbjct: 61 AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120
Query: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL
Sbjct: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240
LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240
Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300
KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP
Sbjct: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300
Query: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360
VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV
Sbjct: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360
Query: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420
PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL
Sbjct: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420
Query: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469
PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE
Sbjct: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 979 bits (2530), Expect = 0.0
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60
MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH
Sbjct: 1 MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSH 60
Query: 61 AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120
AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES
Sbjct: 61 AHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGES 120
Query: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL
Sbjct: 121 GAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGL 180
Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240
LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHV 240
Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300
KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP
Sbjct: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGP 300
Query: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360
VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV
Sbjct: 301 VRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEV 360
Query: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420
PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL
Sbjct: 361 PHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVL 420
Query: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469
PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE
Sbjct: 421 PFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE 469
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 194 bits (494), Expect = 1e-49
Identities = 131/361 (36%), Positives = 188/361 (52%), Gaps = 58/361 (16%)
Query: 119 ESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL----LQILLS 174
ES + G + + W +L ++++ + F L +IP+E + L+ LLS
Sbjct: 52 ESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLS 111
Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS----VGLWVLSGIVAF 230
FA GGLLG+ FLHL+P A ++ PG G+G L +GLWV++GI+ F
Sbjct: 112 FALGGLLGNVFLHLLPEAW---AYTCSASPG------GEGQSLQQQQQLGLWVIAGILTF 162
Query: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290
L +EK +KE+ +S+ K+
Sbjct: 163 LALEKMFL------------------------------DSKEEGTSQAPNKDPTAAAAAL 192
Query: 291 GGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGL 347
G G Q A E G ++VSGYLNL A+ NFT GLA+ ASF + +
Sbjct: 193 NG------GHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKI 246
Query: 348 GILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEG--GA 405
G+LTTM +LLHE+PHEVGDFAIL+++G + A +LQL TA+G L G A+ T+ G
Sbjct: 247 GLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV 306
Query: 406 VGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLI 465
VG A WVLPFT+GGF+Y+A V+VLP+LL E P +SL ++L L G+++MVL
Sbjct: 307 VGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLF 366
Query: 466 A 466
+
Sbjct: 367 S 367
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 189 bits (480), Expect = 5e-48
Identities = 129/359 (35%), Positives = 186/359 (51%), Gaps = 61/359 (16%)
Query: 119 ESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL----LQILLS 174
ES + G + + W +L ++++ + F L +IP+E + L+ LLS
Sbjct: 52 ESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLS 111
Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS----VGLWVLSGIVAF 230
FA GGLLG+ FLHL+P A ++ PG G+G L +GLWV++GI+ F
Sbjct: 112 FALGGLLGNVFLHLLPEAW---AYTCSASPG------GEGQSLQQQQQLGLWVIAGILTF 162
Query: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290
L +EK +KE+ +S+ K+
Sbjct: 163 LALEKMFL------------------------------DSKEEGTSQAPNKDPTAAAAAL 192
Query: 291 GGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGL 347
G G Q A E G ++VSGYLNL A+ NFT GLA+ ASF + +
Sbjct: 193 NG------GHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKI 246
Query: 348 GILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVG 407
G+LTTM +LLHE+PHEVGDFAIL+++G + A +LQL TA+G L G A+ T+
Sbjct: 247 GLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV 306
Query: 408 SEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIA 466
E A WVLPFT+GGF+Y+A V+VLP+LL E P +SL ++L L G+++MVL +
Sbjct: 307 EETA-----AWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS 360
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 146 bits (369), Expect = 3e-35
Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)
Query: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
G P ++ L + Y AT+LI F L L+ +LQ LS
Sbjct: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
A G L GDA LHL P L H+H S G P + L +L+G+ AF +
Sbjct: 342 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 391
Query: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
E + G GHS SH+ G H HG Q + E ++ +
Sbjct: 392 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 438
Query: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
+ V ++ P N E + +LR+ Y+ D HNF DGLA+GA+F
Sbjct: 439 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 497
Query: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
G+ T++ V HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG AL
Sbjct: 498 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 552
Query: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
AVG W+L G F+YVA +LP +L+ P L LL +GLLGG +
Sbjct: 553 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 609
Query: 462 MVLIAHLE 469
++L++ E
Sbjct: 610 LLLLSLYE 617
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 146 bits (369), Expect = 3e-35
Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)
Query: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
G P ++ L + Y AT+LI F L L+ +LQ LS
Sbjct: 307 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 366
Query: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
A G L GDA LHL P L H+H S G P + L +L+G+ AF +
Sbjct: 367 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 416
Query: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
E + G GHS SH+ G H HG Q + E ++ +
Sbjct: 417 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 463
Query: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
+ V ++ P N E + +LR+ Y+ D HNF DGLA+GA+F
Sbjct: 464 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 522
Query: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
G+ T++ V HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG AL
Sbjct: 523 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 577
Query: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
AVG W+L G F+YVA +LP +L+ P L LL +GLLGG +
Sbjct: 578 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 634
Query: 462 MVLIAHLE 469
++L++ E
Sbjct: 635 LLLLSLYE 642
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 140 bits (352), Expect = 3e-33
Identities = 103/350 (29%), Positives = 158/350 (45%), Gaps = 45/350 (12%)
Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
+ Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L
Sbjct: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426
Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKF------------VRHVKG 242
H E P GH H +G I + + ++ GI F ++EK + V G
Sbjct: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNG 482
Query: 243 GHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVR 302
GHSH H +S G G+ + + K + + E P+
Sbjct: 483 HVGHSH-HLALNSELSDQAGRGKSASTIQLKSPEDSQAAEM----------------PIG 525
Query: 303 PQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPH 362
A K + + + L D HNF DGLAIGA+F G+ TT+ +L HE+PH
Sbjct: 526 SMTASNRKCKA-ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPH 584
Query: 363 EVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPF 422
E+GDFA+L+ SG S K A+ + ++++ A G L S A W+
Sbjct: 585 EMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTV 636
Query: 423 TAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
TAG F+Y++ V +LPE+ + + LL+ GL+ G + ++L+A E
Sbjct: 637 TAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 686
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 130 bits (326), Expect = 3e-30
Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)
Query: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180
AP DL + L + AL +L +P +L L + PR R LL L + A G L
Sbjct: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257
Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236
GDA LHL+PHA E H+G G + L GL VL G+ V+E
Sbjct: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304
Query: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293
+ RH +G + TR + + Q++ E + Q+ +
Sbjct: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360
Query: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352
P P Q ++ + G D+ ++ L D HN TDGLAIGA+F G G+ TT
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417
Query: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412
+ V HE+PHE+GDFA+L+QSG S + RL LL+ V G A+L VG +
Sbjct: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470
Query: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469
WV TAG F+YVA V +LP LLR PL + LL+ LGLL G +M+ I LE
Sbjct: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 130 bits (326), Expect = 3e-30
Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)
Query: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180
AP DL + L + AL +L +P +L L + PR R LL L + A G L
Sbjct: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257
Query: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236
GDA LHL+PHA E H+G G + L GL VL G+ V+E
Sbjct: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304
Query: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293
+ RH +G + TR + + Q++ E + Q+ +
Sbjct: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360
Query: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352
P P Q ++ + G D+ ++ L D HN TDGLAIGA+F G G+ TT
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417
Query: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412
+ V HE+PHE+GDFA+L+QSG S + RL LL+ V G A+L VG +
Sbjct: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470
Query: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469
WV TAG F+YVA V +LP LLR PL + LL+ LGLL G +M+ I LE
Sbjct: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 127 bits (318), Expect = 3e-29
Identities = 97/339 (28%), Positives = 151/339 (44%), Gaps = 60/339 (17%)
Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
+ Y+ A L++ L+ S +R +LQ+ + A G L GDA LHLIP L
Sbjct: 367 YGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLG 426
Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEK-FVRHVKGGHGHSHGHGHA 253
H E P GH H +G I + + ++ GI F ++EK F+ V
Sbjct: 427 LHKQ---EAPEFGHFHESKGHIWKL-MGLIGGIHGFFLIEKCFILLV------------- 469
Query: 254 HSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL 313
S +K+S E+ + + P+ A K
Sbjct: 470 ---------------SPNDKKSPEDSQAA---------------EMPIGSMTASNRKCKA 499
Query: 314 DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQS 373
+ + + L D HNF DGLAIGA+F G+ TT+ +L HE+PHE+GDFA+L+ S
Sbjct: 500 -ISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
Query: 374 GCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATV 433
G S K A+ + ++++ A G L S A W+ TAG F+Y++ V
Sbjct: 559 GLSMKTAILMNFISSLTAFMGLYIGL--------SVSADPCVQDWIFTVTAGMFLYLSLV 610
Query: 434 SVLPELLREASP---LQSLLEVLGLLGGVIMMVLIAHLE 469
+LPE+ + + LL+ GL+ G + ++L+A E
Sbjct: 611 EMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYE 649
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 112 bits (281), Expect = 6e-25
Identities = 121/417 (29%), Positives = 175/417 (41%), Gaps = 88/417 (21%)
Query: 85 HEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVL 144
H H HSH ++H GHGH H H + E + DAV ALG L
Sbjct: 462 HSQGGHDHSHQHAH------GHGHSHGHESNKFLE--------EYDAVLKGLVALGGIYL 507
Query: 145 ISAAPFFV-LFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHA----LEPHSHH 199
+ + +F + + + Q G L D L+ P + L+P +
Sbjct: 508 LFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLA-- 565
Query: 200 TLEQPGHGHSHSGQGPILSVGLWVLSGIVA-----FLVVE--KFVRHVKGGHGHSHGHGH 252
G S + + L L G +L +E K + H HS G
Sbjct: 566 -----GTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIEEEKII-----DHSHSDGLHT 615
Query: 253 AHSHT--RGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEK 310
H H +H H + ++ K + + K + GP
Sbjct: 616 IHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHH-----------SHGPCHS------- 657
Query: 311 RGLDLRVSGYLNLA-----ADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
G DL+ +G N+A D HNF+DGLAIGA+F G GI T++ V HE+PHE+G
Sbjct: 658 -GSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
Query: 366 DFAILVQSGCSKKQAMRLQLLTA----VGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
DFA+L+++G + KQA+ LL+A +G L GTA G + I W+
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV------GQYANNIT-----LWIFA 765
Query: 422 FTAGGFIYVATVSVLPELLREAS--------PL-QSLLEVLGLLGGVIMMVLIAHLE 469
TAG F+YVA V +LPE+L P+ Q +L+ LGLL G +M++IA E
Sbjct: 766 VTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
W + + +IS + L+P+ N + LL L++ A G + GDA LHL+PH+
Sbjct: 407 WICGIISITVISLLSLLGVILVPI-INQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQG 465
Query: 195 PHSHHTLEQPGHGHSHSGQG-------PILSVGLWVLSGIVAFLVVEKFVRHVK 241
H H GHGHSH + + GL L GI ++E +R K
Sbjct: 466 GHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFK 519
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 20/106 (18%)
Query: 35 HDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTH--------ESIWHGHTHDHDH----- 81
H+DL D H + ++ H HSH H H H H S+ H D
Sbjct: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETV 160
Query: 82 --GHSHEDLH-HGHSHGYSHESLYHRGHGH-DHEHSHGGYGESGAP 123
+D H H H+H H +HR H H DH ++H + +S P
Sbjct: 161 EVSVKSDDKHMHDHNHRLRH---HHRLHHHLDHNNTHHFHNDSITP 203
Score = 37.4 bits (85), Expect = 0.029
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 8/62 (12%)
Query: 39 QEDFHGHSHRHSHEDFHHGHSHAHGHGH--THESIWHGHTHDHDHGHSHEDLHHGHSHGY 96
+E HSH H HA H H ++++ H H H HSH HSHG
Sbjct: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSH------HSHGP 654
Query: 97 SH 98
H
Sbjct: 655 CH 656
Score = 36.2 bits (82), Expect = 0.066
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
HSH+ G HE H H+H HG + L H+H + H+ H H H HS
Sbjct: 607 HSHSDGLHTIHEHDLHAAAHNH-HGENKTVLRK-HNHQWHHK---HSHHSHGPCHSGSDL 661
Query: 118 GESGAPGI 125
E+G I
Sbjct: 662 KETGIANI 669
Score = 35.8 bits (81), Expect = 0.086
Identities = 13/24 (54%), Positives = 14/24 (58%)
Query: 45 HSHRHSHEDFHHGHSHAHGHGHTH 68
H HS H H HAHGHGH+H
Sbjct: 458 HLLPHSQGGHDHSHQHAHGHGHSH 481
Score = 35.0 bits (79), Expect = 0.15
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 32 DDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG 91
D LH + D H +H H HG + H H+ WH H H H HSH H G
Sbjct: 611 DGLHTIHEHDLHAAAHNH------HGENKTVLRKHNHQ--WH---HKHSH-HSHGPCHSG 658
Score = 34.3 bits (77), Expect = 0.25
Identities = 12/24 (50%), Positives = 13/24 (54%)
Query: 47 HRHSHEDFHHGHSHAHGHGHTHES 70
H D H H+H HGH H HES
Sbjct: 462 HSQGGHDHSHQHAHGHGHSHGHES 485
Score = 33.5 bits (75), Expect = 0.43
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
Query: 11 VAVGLLTW-ATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHE 52
+AVG ++ A L LL GGHD H + HGH H H HE
Sbjct: 446 LAVGTMSGDALLHLLPHSQGGHDHSH----QHAHGHGHSHGHE 484
Score = 30.0 bits (66), Expect = 4.7
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKET 283
+G H HSH H H+H+H S STK + EKET
Sbjct: 119 EGKHFHSHNHQHSHNHL-NSENQTVTSVSTKRNHKC-DPEKET 159
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 112 bits (281), Expect = 6e-25
Identities = 121/417 (29%), Positives = 175/417 (41%), Gaps = 88/417 (21%)
Query: 85 HEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVL 144
H H HSH ++H GHGH H H + E + DAV ALG L
Sbjct: 462 HSQGGHDHSHQHAH------GHGHSHGHESNKFLE--------EYDAVLKGLVALGGIYL 507
Query: 145 ISAAPFFV-LFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHA----LEPHSHH 199
+ + +F + + + Q G L D L+ P + L+P +
Sbjct: 508 LFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLA-- 565
Query: 200 TLEQPGHGHSHSGQGPILSVGLWVLSGIVA-----FLVVE--KFVRHVKGGHGHSHGHGH 252
G S + + L L G +L +E K + H HS G
Sbjct: 566 -----GTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIEEEKII-----DHSHSDGLHT 615
Query: 253 AHSHT--RGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEK 310
H H +H H + ++ K + + K + GP
Sbjct: 616 IHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHH-----------SHGPCHS------- 657
Query: 311 RGLDLRVSGYLNLA-----ADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
G DL+ +G N+A D HNF+DGLAIGA+F G GI T++ V HE+PHE+G
Sbjct: 658 -GSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
Query: 366 DFAILVQSGCSKKQAMRLQLLTA----VGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
DFA+L+++G + KQA+ LL+A +G L GTA G + I W+
Sbjct: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV------GQYANNIT-----LWIFA 765
Query: 422 FTAGGFIYVATVSVLPELLREAS--------PL-QSLLEVLGLLGGVIMMVLIAHLE 469
TAG F+YVA V +LPE+L P+ Q +L+ LGLL G +M++IA E
Sbjct: 766 VTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
W + + +IS + L+P+ N + LL L++ A G + GDA LHL+PH+
Sbjct: 407 WICGIISITVISLLSLLGVILVPI-INQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQG 465
Query: 195 PHSHHTLEQPGHGHSHSGQG-------PILSVGLWVLSGIVAFLVVEKFVRHVK 241
H H GHGHSH + + GL L GI ++E +R K
Sbjct: 466 GHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFK 519
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 20/106 (18%)
Query: 35 HDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTH--------ESIWHGHTHDHDH----- 81
H+DL D H + ++ H HSH H H H H S+ H D
Sbjct: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETV 160
Query: 82 --GHSHEDLH-HGHSHGYSHESLYHRGHGH-DHEHSHGGYGESGAP 123
+D H H H+H H +HR H H DH ++H + +S P
Sbjct: 161 EVSVKSDDKHMHDHNHRLRH---HHRLHHHLDHNNTHHFHNDSITP 203
Score = 37.4 bits (85), Expect = 0.029
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 8/62 (12%)
Query: 39 QEDFHGHSHRHSHEDFHHGHSHAHGHGH--THESIWHGHTHDHDHGHSHEDLHHGHSHGY 96
+E HSH H HA H H ++++ H H H HSH HSHG
Sbjct: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSH------HSHGP 654
Query: 97 SH 98
H
Sbjct: 655 CH 656
Score = 36.2 bits (82), Expect = 0.066
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
HSH+ G HE H H+H HG + L H+H + H+ H H H HS
Sbjct: 607 HSHSDGLHTIHEHDLHAAAHNH-HGENKTVLRK-HNHQWHHK---HSHHSHGPCHSGSDL 661
Query: 118 GESGAPGI 125
E+G I
Sbjct: 662 KETGIANI 669
Score = 35.8 bits (81), Expect = 0.086
Identities = 13/24 (54%), Positives = 14/24 (58%)
Query: 45 HSHRHSHEDFHHGHSHAHGHGHTH 68
H HS H H HAHGHGH+H
Sbjct: 458 HLLPHSQGGHDHSHQHAHGHGHSH 481
Score = 35.0 bits (79), Expect = 0.15
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 32 DDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG 91
D LH + D H +H H HG + H H+ WH H H H HSH H G
Sbjct: 611 DGLHTIHEHDLHAAAHNH------HGENKTVLRKHNHQ--WH---HKHSH-HSHGPCHSG 658
Score = 34.3 bits (77), Expect = 0.25
Identities = 12/24 (50%), Positives = 13/24 (54%)
Query: 47 HRHSHEDFHHGHSHAHGHGHTHES 70
H D H H+H HGH H HES
Sbjct: 462 HSQGGHDHSHQHAHGHGHSHGHES 485
Score = 33.5 bits (75), Expect = 0.43
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
Query: 11 VAVGLLTW-ATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHE 52
+AVG ++ A L LL GGHD H + HGH H H HE
Sbjct: 446 LAVGTMSGDALLHLLPHSQGGHDHSH----QHAHGHGHSHGHE 484
Score = 30.0 bits (66), Expect = 4.7
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKET 283
+G H HSH H H+H+H S STK + EKET
Sbjct: 119 EGKHFHSHNHQHSHNHL-NSENQTVTSVSTKRNHKC-DPEKET 159
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 102 bits (253), Expect = 1e-21
Identities = 107/386 (27%), Positives = 160/386 (41%), Gaps = 66/386 (17%)
Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
+ E+ E G P AV +W Y L +IS ++P + ++ L
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186
Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
L ++ A G L +A LIP A G P+ +S V
Sbjct: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228
Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
G F EK ++ + K + H HGH H S + S QE EK
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286
Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
SSE + K +K GS +D Q+A +G+ D+ ++ +D
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345
Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
HNF DGLAIGASF GI T++ +L E PHE+GDF IL+ +G S +QA+ L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
A G A +L GS + W+ G F+Y++ + PE+
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456
Query: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
R+ S L +++ LGLL G +MV++
Sbjct: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 102 bits (253), Expect = 1e-21
Identities = 107/386 (27%), Positives = 160/386 (41%), Gaps = 66/386 (17%)
Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
+ E+ E G P AV +W Y L +IS ++P + ++ L
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186
Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
L ++ A G L +A LIP A G P+ +S V
Sbjct: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228
Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
G F EK ++ + K + H HGH H S + S QE EK
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286
Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
SSE + K +K GS +D Q+A +G+ D+ ++ +D
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345
Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
HNF DGLAIGASF GI T++ +L E PHE+GDF IL+ +G S +QA+ L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
A G A +L GS + W+ G F+Y++ + PE+
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456
Query: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
R+ S L +++ LGLL G +MV++
Sbjct: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 100 bits (249), Expect = 3e-21
Identities = 106/386 (27%), Positives = 162/386 (41%), Gaps = 66/386 (17%)
Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
+ E+ E G P AV +W + + LI+ A + ++P + R +
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSR-V 186
Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
L ++ + G LL +A LIP A G P+ +S V
Sbjct: 187 LTYFIALSIGTLLSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228
Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
G F EK ++ + K + H HGH H S + S QE EK
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286
Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
SSE + K +K GS +D Q+A +G+ D+ ++ +D
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345
Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
HNF DGLAIGASF GI T++ +L E PHE+GDF IL+ +G S +QA+ L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
A G A +L GS + W+ G F+Y++ + PE+
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456
Query: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
R+ S L +++ LGLL G +MV++
Sbjct: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 95.1 bits (235), Expect = 1e-19
Identities = 58/171 (33%), Positives = 92/171 (53%), Gaps = 14/171 (8%)
Query: 306 AEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
+ EE + + ++ + D HNF+DGLAIGA+F G G+ T++ V HE+PHE+G
Sbjct: 583 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 642
Query: 366 DFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAG 425
DFA+L+++G + KQA+ L+A+ A G A + A + W+ TAG
Sbjct: 643 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSM-------WIFALTAG 695
Query: 426 GFIYVATVSVLPELLREASPLQS-------LLEVLGLLGGVIMMVLIAHLE 469
F+YVA V ++PE+L + L+ G+L G +M+LI+ E
Sbjct: 696 LFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 746
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
W A +IS + L+P+ N + LL L++ A G L GDAFLHL+PH+
Sbjct: 325 WVGGFIAISIISFLSLLGVILVPL-MNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHA 383
Query: 195 PHSH-HTLEQPGHGHSHSGQGPILS 218
H H H+ E+P +GP+ S
Sbjct: 384 SHHHSHSHEEPA---MEMKRGPLFS 405
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 66 HTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGI 125
H H H H DH+H HS + H H H HE +H H H H+H G++ +
Sbjct: 91 HIHHD--HDHHSDHEH-HSDHERHSDHEHHSDHE--HHSDHDHHSHHNHAASGKNKRKAL 145
Query: 126 KQDLDA 131
D D+
Sbjct: 146 CPDHDS 151
Score = 40.0 bits (92), Expect = 0.005
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 49 HSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGH 108
H H D H H H H S H H DH+H HS D H H+H S ++ +
Sbjct: 91 HIHHDHDHHSDHEHHSDHERHSD-HEHHSDHEH-HSDHDHHSHHNHAASGKN-KRKALCP 147
Query: 109 DHEHSHGGYGESGAPG 124
DH+ G + G
Sbjct: 148 DHDSDSSGKDPRNSQG 163
Score = 39.3 bits (90), Expect = 0.008
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 34 LHDDLQEDFHGHSHRHSH-EDFHHGHSHAHGHGHTHESIWHG-----HTHDHDHGHSHED 87
L D QE H S + + E+ +HAH +E + G H+H HD +D
Sbjct: 494 LRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
Query: 88 LHHGHSHGYSHESLYHRGHGHDHEHSH 114
L H H H Y H L+H H + H HSH
Sbjct: 554 LIH-HHHDY-HHILHHHHHQNHHPHSH 578
Score = 38.5 bits (88), Expect = 0.013
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 58 HSHAHGH-GHTHESIWHGHTHDHDHGHSHEDLHHGHSHG--YSHESLYHRG 105
HSH H G + + I H H + H H H HH HSH YS E L G
Sbjct: 541 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAG 591
Score = 35.0 bits (79), Expect = 0.15
Identities = 15/43 (34%), Positives = 16/43 (37%), Gaps = 2/43 (4%)
Query: 43 HGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH 85
H H H HE HH H H H HDH H+H
Sbjct: 94 HDHDHHSDHE--HHSDHERHSDHEHHSDHEHHSDHDHHSHHNH 134
Score = 34.3 bits (77), Expect = 0.25
Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 11/89 (12%)
Query: 34 LHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL----- 88
+H D H HS + H H H H H + H H H+H S ++
Sbjct: 90 IHIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSD---HDHHSHHNHAASGKNKRKALC 146
Query: 89 --HHGHSHGYSHESLYHRGHGHDHEHSHG 115
H S G + +G H EH+ G
Sbjct: 147 PDHDSDSSGKDPRNSQGKG-AHRPEHASG 174
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)
Query: 31 HDDLHDDL-QEDFHGHSHRHSHEDFHHGHSHAHGHGHTH 68
H HD L Q D H H H HH H H + H H+H
Sbjct: 541 HSHFHDTLGQSDDLIHHHHDYHHILHH-HHHQNHHPHSH 578
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 93.2 bits (230), Expect = 5e-19
Identities = 95/349 (27%), Positives = 141/349 (40%), Gaps = 58/349 (16%)
Query: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
+ E+ E G P AV +W Y L +IS ++P + ++ L
Sbjct: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186
Query: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
L ++ A G L +A LIP A G P+ +S V
Sbjct: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228
Query: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
G F EK ++ + K + H HGH H S + S QE EK
Sbjct: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286
Query: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
SSE + K +K GS +D Q+A +G+ D+ ++ +D
Sbjct: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345
Query: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
HNF DGLAIGASF GI T++ +L E PHE+GDF IL+ +G S +QA+ L+
Sbjct: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
Query: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVL 436
A G A +L GS + W+ G F+Y++ ++
Sbjct: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMM 445
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 86.3 bits (212), Expect = 6e-17
Identities = 47/131 (35%), Positives = 74/131 (56%), Gaps = 7/131 (5%)
Query: 306 AEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
+ EE + + ++ + D HNF+DGLAIGA+F G G+ T++ V HE+PHE+G
Sbjct: 308 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 367
Query: 366 DFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAG 425
DFA+L+++G + KQA+ L+A+ A G A + A + W+ TAG
Sbjct: 368 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSM-------WIFALTAG 420
Query: 426 GFIYVATVSVL 436
F+YVA V ++
Sbjct: 421 LFMYVALVDMV 431
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
W A +IS + L+P+ N + LL L++ A G L GDAFLHL+PH+
Sbjct: 50 WVGGFIAISIISFLSLLGVILVPL-MNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHA 108
Query: 195 PHSH-HTLEQPGHGHSHSGQGPILS 218
H H H+ E+P +GP+ S
Sbjct: 109 SHHHSHSHEEPA---MEMKRGPLFS 130
Score = 39.3 bits (90), Expect = 0.008
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 34 LHDDLQEDFHGHSHRHSH-EDFHHGHSHAHGHGHTHESIWHG-----HTHDHDHGHSHED 87
L D QE H S + + E+ +HAH +E + G H+H HD +D
Sbjct: 219 LRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 278
Query: 88 LHHGHSHGYSHESLYHRGHGHDHEHSH 114
L H H H Y H L+H H + H HSH
Sbjct: 279 LIH-HHHDY-HHILHHHHHQNHHPHSH 303
Score = 38.5 bits (88), Expect = 0.013
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 58 HSHAHGH-GHTHESIWHGHTHDHDHGHSHEDLHHGHSHG--YSHESLYHRG 105
HSH H G + + I H H + H H H HH HSH YS E L G
Sbjct: 266 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAG 316
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)
Query: 31 HDDLHDDL-QEDFHGHSHRHSHEDFHHGHSHAHGHGHTH 68
H HD L Q D H H H HH H H + H H+H
Sbjct: 266 HSHFHDTLGQSDDLIHHHHDYHHILHH-HHHQNHHPHSH 303
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 84.7 bits (208), Expect = 2e-16
Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)
Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
+W Y + +I+ A L L P+ S +L + A G L +A LIP A
Sbjct: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186
Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
+P +E+ + V G E+ ++ + +G + G
Sbjct: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227
Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
H H G+ G QE++ + K + E G S V +DG
Sbjct: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284
Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E
Sbjct: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344
Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P +
Sbjct: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395
Query: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
G F+Y++ + PE +LRE + +++ G+L G ++LI
Sbjct: 396 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 450
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 84.7 bits (208), Expect = 2e-16
Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)
Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
+W Y + +I+ A L L P+ S +L + A G L +A LIP A
Sbjct: 61 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 119
Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
+P +E+ + V G E+ ++ + +G + G
Sbjct: 120 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 160
Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
H H G+ G QE++ + K + E G S V +DG
Sbjct: 161 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 217
Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E
Sbjct: 218 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 277
Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P +
Sbjct: 278 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 328
Query: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
G F+Y++ + PE +LRE + +++ G+L G ++LI
Sbjct: 329 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 383
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 84.7 bits (208), Expect = 2e-16
Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)
Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
+W Y + +I+ A L L P+ S +L + A G L +A LIP A
Sbjct: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186
Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
+P +E+ + V G E+ ++ + +G + G
Sbjct: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227
Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
H H G+ G QE++ + K + E G S V +DG
Sbjct: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284
Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E
Sbjct: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344
Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P +
Sbjct: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395
Query: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
G F+Y++ + PE +LRE + +++ G+L G ++LI
Sbjct: 396 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 450
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 84.3 bits (207), Expect = 2e-16
Identities = 81/320 (25%), Positives = 129/320 (40%), Gaps = 46/320 (14%)
Query: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
+W Y + +I+ A L L P+ S +L + A G L +A LIP A
Sbjct: 128 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 186
Query: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
+P +E+ + V G E+ ++ + +G + G
Sbjct: 187 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 227
Query: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
H H G+ G QE++ + K + E G S V +DG
Sbjct: 228 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 284
Query: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E
Sbjct: 285 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 344
Query: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P +
Sbjct: 345 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 395
Query: 420 LPFTAGGFIYVATVSVLPEL 439
G F+Y++ + PE+
Sbjct: 396 FALAGGMFLYISLADMFPEM 415
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/96 (37%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 29 GGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL 88
G H++ D H H H HSHE HGH H H H H H HD H H
Sbjct: 336 GAQRHSHNNNSSDLHPHKH-HSHEQHPHGH-HPHAH--------HPHEHDTHRQHPHGHH 385
Query: 89 HHGHSHGYSHESLYHRGHG-HDHEHSHGGYGESGAP 123
HGH H + H H HG H H H YG P
Sbjct: 386 PHGH-HPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP 420
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/84 (35%), Positives = 33/84 (39%), Gaps = 16/84 (19%)
Query: 31 HDDLHDDLQEDFHGHSHR--HSHEDFHHGHSHAHGHGHTHESIWHGHTHD-HDHG----H 83
H HD ++ HGH H H HGH H HGH H H HD D+G
Sbjct: 370 HPHEHDTHRQHPHGHHPHGHHPHGHHPHGH-HPHGH--------HPHCHDFQDYGPCDPP 420
Query: 84 SHEDLHHGHSHGYSHESLYHRGHG 107
H H H HG L RG G
Sbjct: 421 PHNQGHCCHGHGPPPGHLRRRGPG 444
Score = 38.9 bits (89), Expect = 0.010
Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 20/71 (28%)
Query: 193 LEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
L PH HH+ EQ HGH P + H + HGH H HGH
Sbjct: 349 LHPHKHHSHEQHPHGHHPHAHHP------------------HEHDTHRQHPHGH-HPHGH 389
Query: 253 AHSHTRGSHGH 263
H H HGH
Sbjct: 390 -HPHGHHPHGH 399
Score = 36.6 bits (83), Expect = 0.050
Identities = 27/88 (30%), Positives = 28/88 (31%), Gaps = 34/88 (38%)
Query: 190 PHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHG 249
PHA PH H T Q HGH G P H G H H H
Sbjct: 366 PHAHHPHEHDTHRQHPHGHHPHGHHP--------------------HGHHPHGHHPHGH- 404
Query: 250 HGHAHS-----------HTRG--SHGHG 264
H H H H +G HGHG
Sbjct: 405 HPHCHDFQDYGPCDPPPHNQGHCCHGHG 432
Score = 31.6 bits (70), Expect = 1.6
Identities = 22/73 (30%), Positives = 22/73 (30%), Gaps = 25/73 (34%)
Query: 191 HALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGH 250
H PH HH H H Q P H HGH H H
Sbjct: 357 HEQHPHGHHPHAHHPHEHDTHRQHP-----------------------HGHHPHGH-HPH 392
Query: 251 GHAHSHTRGSHGH 263
GH H H HGH
Sbjct: 393 GH-HPHGHHPHGH 404
>gi|156231037 kininogen 1 isoform 1 [Homo sapiens]
Length = 644
Score = 60.8 bits (146), Expect = 2e-09
Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 19/96 (19%)
Query: 31 HDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH----- 85
HD H+ ++ GH H+H + GH H GHG + HGH H GH H
Sbjct: 429 HDWGHEKQRKHNLGHGHKHERDQ---GHGHQRGHG-----LGHGHEQQHGLGHGHKFKLD 480
Query: 86 EDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESG 121
+DL H H H GH H H H HG + G
Sbjct: 481 DDLEHQGGHVLDH------GHKHKHGHGHGKHKNKG 510
Score = 57.0 bits (136), Expect = 4e-08
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 20/79 (25%)
Query: 57 GHSHAHGHGHTHE---SIWHGHTHDHDHGHSHEDLH---HGH--SHGYSH-------ESL 101
GH+ H GH + ++ HGH H+ D GH H+ H HGH HG H + L
Sbjct: 424 GHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDL 483
Query: 102 YHRG-----HGHDHEHSHG 115
H+G HGH H+H HG
Sbjct: 484 EHQGGHVLDHGHKHKHGHG 502
Score = 40.8 bits (94), Expect = 0.003
Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 8/52 (15%)
Query: 74 GHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGH------GHDHEHSHG-GYG 118
GHT HD GH + H+ HG+ HE GH GH HE HG G+G
Sbjct: 424 GHTRRHDWGHEKQRKHN-LGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHG 474
Score = 38.5 bits (88), Expect = 0.013
Identities = 32/112 (28%), Positives = 42/112 (37%), Gaps = 16/112 (14%)
Query: 196 HSHHTLEQPGHGHSHS---GQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
H H GHGH G G GL G ++ + H +GGH HGH H
Sbjct: 443 HGHKHERDQGHGHQRGHGLGHGHEQQHGL----GHGHKFKLDDDLEH-QGGHVLDHGHKH 497
Query: 253 AHSHTRGSH-----GHGRQERSTKEKQSSEEEEKETRGVQ---KRRGGSTVP 296
H H G H +G+ E +S E+ T Q K G + +P
Sbjct: 498 KHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTPIP 549
Score = 35.4 bits (80), Expect = 0.11
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 9/46 (19%)
Query: 30 GHDDLHDDLQEDFHGHSHRHSHED---------FHHGHSHAHGHGH 66
GH H Q+ GH H+ +D HGH H HGHGH
Sbjct: 458 GHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH 503
Score = 32.0 bits (71), Expect = 1.2
Identities = 13/27 (48%), Positives = 14/27 (51%), Gaps = 3/27 (11%)
Query: 243 GHGHSHGHGHAHSHTRG---SHGHGRQ 266
GHGH H H H RG HGH +Q
Sbjct: 442 GHGHKHERDQGHGHQRGHGLGHGHEQQ 468
>gi|222080086 zinc transporter like 2 [Homo sapiens]
Length = 376
Score = 60.1 bits (144), Expect = 4e-09
Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 15/102 (14%)
Query: 55 HHGHSHAHGHGHTH-ESIWHG---HTHDH-DHGHSHEDLHHGHSHGYSHESLYHRGHGHD 109
H GH H+HG GH H S+++G H H DH HSHE + HG +H + H HGH
Sbjct: 161 HGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHE-VKHGAAHSHDH------AHGHG 213
Query: 110 HEHSHGGYGESGAPG-IKQDLDAVTLWAYA--LGATVLISAA 148
H HSH G G +Q L V L A LG+ +I++A
Sbjct: 214 HFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASA 255
Score = 39.7 bits (91), Expect = 0.006
Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 9/70 (12%)
Query: 242 GGHGHSHGHGHAHSHT------RGSHGHGRQERSTKEKQSSEEEEKETRG---VQKRRGG 292
GGHGHSHG GH HSH+ +HGH S + K + G G
Sbjct: 162 GGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGP 221
Query: 293 STVPKDGPVR 302
S GP R
Sbjct: 222 SLKETTGPSR 231
Score = 39.3 bits (90), Expect = 0.008
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 16/109 (14%)
Query: 166 RSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLS 225
R LL +L F L+G + + H HSH + GHGHSHS + + L
Sbjct: 140 RLLLVSILGFVVN-LIG---IFVFKHGGHGHSHGS----GHGHSHS----LFNGALDQAH 187
Query: 226 GIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ 274
G V VK G HSH H H H H G +E + +Q
Sbjct: 188 GHVDHC----HSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQ 232
>gi|40255009 zinc transporter like 2 [Homo sapiens]
Length = 376
Score = 60.1 bits (144), Expect = 4e-09
Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 15/102 (14%)
Query: 55 HHGHSHAHGHGHTH-ESIWHG---HTHDH-DHGHSHEDLHHGHSHGYSHESLYHRGHGHD 109
H GH H+HG GH H S+++G H H DH HSHE + HG +H + H HGH
Sbjct: 161 HGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHE-VKHGAAHSHDH------AHGHG 213
Query: 110 HEHSHGGYGESGAPG-IKQDLDAVTLWAYA--LGATVLISAA 148
H HSH G G +Q L V L A LG+ +I++A
Sbjct: 214 HFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASA 255
Score = 39.7 bits (91), Expect = 0.006
Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 9/70 (12%)
Query: 242 GGHGHSHGHGHAHSHT------RGSHGHGRQERSTKEKQSSEEEEKETRG---VQKRRGG 292
GGHGHSHG GH HSH+ +HGH S + K + G G
Sbjct: 162 GGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGP 221
Query: 293 STVPKDGPVR 302
S GP R
Sbjct: 222 SLKETTGPSR 231
Score = 39.3 bits (90), Expect = 0.008
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 16/109 (14%)
Query: 166 RSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLS 225
R LL +L F L+G + + H HSH + GHGHSHS + + L
Sbjct: 140 RLLLVSILGFVVN-LIG---IFVFKHGGHGHSHGS----GHGHSHS----LFNGALDQAH 187
Query: 226 GIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ 274
G V VK G HSH H H H H G +E + +Q
Sbjct: 188 GHVDHC----HSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQ 232
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/290 (21%), Positives = 114/290 (39%), Gaps = 43/290 (14%)
Query: 151 FVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSH 210
+V +IP+ N R L+++ +G L G A ++P + LE H S
Sbjct: 19 YVAGIIPLAVNFSEER--LKLVTVLGAGLLCGTALAVIVPEGVHALYEDILEGKHHQASE 76
Query: 211 SGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERST 270
+ + I + EK V H H HSH H H++ S G
Sbjct: 77 TH------------NVIASDKAAEKSVVHE---HEHSHDHTQLHAYIGVSLVLGFVFMLL 121
Query: 271 KEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHN 330
++ + V + E R + +++ L L + H
Sbjct: 122 VDQIGNSH----------------------VHSTDDPEAARSSNSKITTTLGL---VVHA 156
Query: 331 FTDGLAIGASFRGGR-GLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAV 389
DG+A+GA+ + + ++ + ++LH+ P G + L+ +G + + + L+ A+
Sbjct: 157 AADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFAL 216
Query: 390 GALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL 439
A + L + ++ G + F+AG F+YVATV VLPE+
Sbjct: 217 AAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV 266
Score = 29.6 bits (65), Expect = 6.1
Identities = 12/38 (31%), Positives = 17/38 (44%)
Query: 52 EDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLH 89
E HH S H + ++ H+H+H H H LH
Sbjct: 68 EGKHHQASETHNVIASDKAAEKSVVHEHEHSHDHTQLH 105
>gi|59938776 cAMP responsive element binding protein 5 isoform delta
[Homo sapiens]
Length = 369
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 20 TLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDF--HHGHSHAHGHG--HTHESIWHGH 75
T+G ++ +G D H HSH H H+ HH + H H H H H H
Sbjct: 115 TMGHMMEMMGSRQDQ----TPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQ 170
Query: 76 THDHDHGHSHEDLHHGHSHGYSHESLY 102
H H H HSH H H H L+
Sbjct: 171 NHPHHHSHSHLHAHPAHHQTSPHPPLH 197
Score = 45.8 bits (107), Expect = 8e-05
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
H H H H H H+++ H + H H H HH H + H+ + H H H H+H +
Sbjct: 132 HHHMHSHPHQHQTLPPHHPYPHQHQH---PAHHPHPQPH-HQQNHPHHHSHSHLHAHPAH 187
Query: 118 GES 120
++
Sbjct: 188 HQT 190
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)
Query: 56 HGHSHAHGHGHTHESIWHGHTHDHDH--GHSHEDLHH--GHSHGYSHESLY-HRGHGHDH 110
H H H+H H H H + H H H H H HH H H +SH L+ H H
Sbjct: 132 HHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTS 191
Query: 111 EHS--HGGYGESGAPGIKQ 127
H H G +P +Q
Sbjct: 192 PHPPLHTGNQAQVSPATQQ 210
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 10/76 (13%)
Query: 49 HSHEDFHHGHSHAHGH-----GHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY- 102
H +G+ + GH G + H H H H H H HH + H + H + +
Sbjct: 103 HHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 162
Query: 103 ----HRGHGHDHEHSH 114
H H H HSH
Sbjct: 163 HPQPHHQQNHPHHHSH 178
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/44 (36%), Positives = 17/44 (38%), Gaps = 2/44 (4%)
Query: 43 HGHSHRHSHEDFHH--GHSHAHGHGHTHESIWHGHTHDHDHGHS 84
H H H H HH H H H H H H H T H H+
Sbjct: 155 HQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHT 198
Score = 29.6 bits (65), Expect = 6.1
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 20/69 (28%)
Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAH 254
PH H TL P H + H Q P H + H +H H H+H
Sbjct: 139 PHQHQTLP-PHHPYPHQHQHPAHHP-------------------HPQPHHQQNHPHHHSH 178
Query: 255 SHTRGSHGH 263
SH H
Sbjct: 179 SHLHAHPAH 187
>gi|59938774 cAMP responsive element binding protein 5 isoform beta
[Homo sapiens]
Length = 501
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 20 TLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDF--HHGHSHAHGHG--HTHESIWHGH 75
T+G ++ +G D H HSH H H+ HH + H H H H H H
Sbjct: 247 TMGHMMEMMGSRQDQ----TPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQ 302
Query: 76 THDHDHGHSHEDLHHGHSHGYSHESLY 102
H H H HSH H H H L+
Sbjct: 303 NHPHHHSHSHLHAHPAHHQTSPHPPLH 329
Score = 45.8 bits (107), Expect = 8e-05
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
H H H H H H+++ H + H H H HH H + H+ + H H H H+H +
Sbjct: 264 HHHMHSHPHQHQTLPPHHPYPHQHQH---PAHHPHPQPH-HQQNHPHHHSHSHLHAHPAH 319
Query: 118 GES 120
++
Sbjct: 320 HQT 322
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)
Query: 56 HGHSHAHGHGHTHESIWHGHTHDHDH--GHSHEDLHH--GHSHGYSHESLY-HRGHGHDH 110
H H H+H H H H + H H H H H HH H H +SH L+ H H
Sbjct: 264 HHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTS 323
Query: 111 EHS--HGGYGESGAPGIKQ 127
H H G +P +Q
Sbjct: 324 PHPPLHTGNQAQVSPATQQ 342
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 10/76 (13%)
Query: 49 HSHEDFHHGHSHAHGH-----GHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY- 102
H +G+ + GH G + H H H H H H HH + H + H + +
Sbjct: 235 HHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 294
Query: 103 ----HRGHGHDHEHSH 114
H H H HSH
Sbjct: 295 HPQPHHQQNHPHHHSH 310
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/44 (36%), Positives = 17/44 (38%), Gaps = 2/44 (4%)
Query: 43 HGHSHRHSHEDFHH--GHSHAHGHGHTHESIWHGHTHDHDHGHS 84
H H H H HH H H H H H H H T H H+
Sbjct: 287 HQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHT 330
Score = 29.6 bits (65), Expect = 6.1
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 20/69 (28%)
Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAH 254
PH H TL P H + H Q P H + H +H H H+H
Sbjct: 271 PHQHQTLP-PHHPYPHQHQHPAHHP-------------------HPQPHHQQNHPHHHSH 310
Query: 255 SHTRGSHGH 263
SH H
Sbjct: 311 SHLHAHPAH 319
>gi|59938772 cAMP responsive element binding protein 5 isoform gamma
[Homo sapiens]
Length = 475
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 20 TLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDF--HHGHSHAHGHG--HTHESIWHGH 75
T+G ++ +G D H HSH H H+ HH + H H H H H H
Sbjct: 221 TMGHMMEMMGSRQDQ----TPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQ 276
Query: 76 THDHDHGHSHEDLHHGHSHGYSHESLY 102
H H H HSH H H H L+
Sbjct: 277 NHPHHHSHSHLHAHPAHHQTSPHPPLH 303
Score = 45.8 bits (107), Expect = 8e-05
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
H H H H H H+++ H + H H H HH H + H+ + H H H H+H +
Sbjct: 238 HHHMHSHPHQHQTLPPHHPYPHQHQH---PAHHPHPQPH-HQQNHPHHHSHSHLHAHPAH 293
Query: 118 GES 120
++
Sbjct: 294 HQT 296
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 7/79 (8%)
Query: 56 HGHSHAHGHGHTHESIWHGHTHDHDH--GHSHEDLHH--GHSHGYSHESLY-HRGHGHDH 110
H H H+H H H H + H H H H H HH H H +SH L+ H H
Sbjct: 238 HHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTS 297
Query: 111 EHS--HGGYGESGAPGIKQ 127
H H G +P +Q
Sbjct: 298 PHPPLHTGNQAQVSPATQQ 316
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 10/76 (13%)
Query: 49 HSHEDFHHGHSHAHGH-----GHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY- 102
H +G+ + GH G + H H H H H H HH + H + H + +
Sbjct: 209 HHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 268
Query: 103 ----HRGHGHDHEHSH 114
H H H HSH
Sbjct: 269 HPQPHHQQNHPHHHSH 284
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/44 (36%), Positives = 17/44 (38%), Gaps = 2/44 (4%)
Query: 43 HGHSHRHSHEDFHH--GHSHAHGHGHTHESIWHGHTHDHDHGHS 84
H H H H HH H H H H H H H T H H+
Sbjct: 261 HQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHT 304
Score = 29.6 bits (65), Expect = 6.1
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 20/69 (28%)
Query: 195 PHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAH 254
PH H TL P H + H Q P H + H +H H H+H
Sbjct: 245 PHQHQTLP-PHHPYPHQHQHPAHHP-------------------HPQPHHQQNHPHHHSH 284
Query: 255 SHTRGSHGH 263
SH H
Sbjct: 285 SHLHAHPAH 293
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,891,453
Number of Sequences: 37866
Number of extensions: 1079700
Number of successful extensions: 10970
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 6510
Number of HSP's gapped (non-prelim): 2354
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.