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Search of human proteins with 239747798
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
(399 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 758 0.0
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 649 0.0
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 642 0.0
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 640 0.0
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 535 e-152
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 532 e-151
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 255 6e-68
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 113 3e-25
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 3e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 54 2e-07
gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 54 2e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 54 3e-07
gi|194473700 Src homology 3 domain-containing guanine nucleotide... 53 4e-07
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 52 7e-07
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 52 9e-07
gi|4557509 cylicin 2 [Homo sapiens] 52 1e-06
gi|154090959 hypothetical protein LOC55747 [Homo sapiens] 52 1e-06
gi|109637759 calpastatin isoform f [Homo sapiens] 51 2e-06
gi|161016767 mucin 21 [Homo sapiens] 51 2e-06
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 50 4e-06
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 50 4e-06
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 50 4e-06
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 50 4e-06
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 50 4e-06
gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 50 4e-06
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 50 5e-06
gi|87299628 biorientation of chromosomes in cell division 1-like... 49 6e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 49 1e-05
gi|109637761 calpastatin isoform g [Homo sapiens] 48 1e-05
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 47 2e-05
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 758 bits (1957), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MYPFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV 60
MYPFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV
Sbjct: 1 MYPFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV 60
Query: 61 SNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKA 120
SNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKA
Sbjct: 61 SNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKA 120
Query: 121 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 180
TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS
Sbjct: 121 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 180
Query: 181 QKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDG 240
QKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDG
Sbjct: 181 QKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDG 240
Query: 241 EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLN 300
EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLN
Sbjct: 241 EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLN 300
Query: 301 IARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATS 360
IARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATS
Sbjct: 301 IARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATS 360
Query: 361 DEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVMKLSFML 399
DEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVMKLSFML
Sbjct: 361 DEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVMKLSFML 399
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 649 bits (1673), Expect = 0.0
Identities = 354/418 (84%), Positives = 365/418 (87%), Gaps = 34/418 (8%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
K+GQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI GGGKSGTVSSQKQPASKATSDKTDS
Sbjct: 324 KKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
ATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+DEE SV IA E KDGEKS TVS
Sbjct: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISR----------------------------- 278
SRKKPALKATSDEKDSFSNITR KKDGEISR
Sbjct: 504 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563
Query: 279 -----TVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFS 333
TV+SEKP GLKA+S E+DSVLNIARGK+DGEKT+RVSSRKKP+L+ATSDEKDSFS
Sbjct: 564 GEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFS 623
Query: 334 NITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
NITREKKDGE SR VSSQKPPALK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLK
Sbjct: 624 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 681
Score = 463 bits (1192), Expect = e-130
Identities = 268/425 (63%), Positives = 304/425 (71%), Gaps = 34/425 (8%)
Query: 3 PFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVS------------------- 43
P +VSSQKQPAEKATSD+KDSVSNIATEIK+G SGTVS
Sbjct: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLN 352
Query: 44 ---------------SQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIF 88
SQKQPA KATSD+ DS NIATEIK+G Q GTVS QKQ A K
Sbjct: 353 IATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
Query: 89 KKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQK 148
++ S+ NIAT I G KSGTVSSQKQPA KAT+D+ DS NIATEIKDG + GTVSSQK
Sbjct: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
Query: 149 QPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEK 208
PAL AT+DEE SV +IA E KDGEKS TVSS+K+PALKAT+DE+DS NI KDGE
Sbjct: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEI 532
Query: 209 SETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNIT 268
S VSSQK P LK T+DEEDSV IA E KDGEKS TVSS K P LKA+S EKDS NI
Sbjct: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIA 592
Query: 269 REKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDE 328
R KKDGE ++ V+S K L+ATSDE+DS NI R K+DGE +R+VSS+K PALK TSDE
Sbjct: 593 RGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 652
Query: 329 KDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPP 388
+DS I RE KDGE SRTVSS+KPP LKATSDE+DSVL+IAR +KDGEK+RTVSS + P
Sbjct: 653 EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQP 712
Query: 389 GLKVM 393
LK +
Sbjct: 713 ALKAI 717
Score = 450 bits (1157), Expect = e-126
Identities = 253/387 (65%), Positives = 299/387 (77%)
Query: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
C +VSSQKQPA KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DEKDSVSNIA
Sbjct: 397 CGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIA 456
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
TEIK+G++SGTVS QK A ++ S+L+IA G KS TVSS+K+PA KATSD+
Sbjct: 457 TEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDE 516
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
DS NI KDG VSSQK P LK T+DEEDSV IA E KDGEKS TVSS+K P
Sbjct: 517 KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
LKA++ E+DSVLNIA KDGEK++ VSS+K+P+L+AT+DE+DS S I E KDGE S
Sbjct: 577 GLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISR 636
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
VSS+K PALK TSDE+DS I RE KDGE SRTV+SEKP GLKATSDE+DSVLNIARG
Sbjct: 637 KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARG 696
Query: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEED 364
K+DGEKTR VSS K+PALKA D++DS N+ EKKD + S TVS QK PALKATSD++D
Sbjct: 697 KKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKD 756
Query: 365 SVLSIAREEKDGEKSRTVSSEQPPGLK 391
SV +I E KDG++S TVSS++ P K
Sbjct: 757 SVSNIPTEIKDGQQSGTVSSQKQPAWK 783
Score = 444 bits (1143), Expect = e-125
Identities = 255/385 (66%), Positives = 281/385 (72%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VS ++ P T D+D +S + S SS++ P T E D S A
Sbjct: 195 NVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+ G VS QKQ A K K S+ NIAT I G SGTVSSQKQPA KATSD+ D
Sbjct: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NIATEIK G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA
Sbjct: 315 SVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS 374
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+D+ DS LNIATEIKDG + TVSSQKQPALKATTDEEDSVS IATEIKDGEKSGTV
Sbjct: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS+K+PALKAT+DEKDS SNI E KDGE S TV+S+KP L ATSDEE SVL+IAR +
Sbjct: 435 SSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENK 494
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
DGEK+R VSSRKKPALKATSDEKDSFSNITR KKDGE SR VSSQKPP LK TSDEEDSV
Sbjct: 495 DGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSV 554
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
L IARE KDGEKSRTVSSE+PPGLK
Sbjct: 555 LGIARENKDGEKSRTVSSEKPPGLK 579
Score = 391 bits (1004), Expect = e-109
Identities = 229/371 (61%), Positives = 270/371 (72%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQKQPA KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +IA E
Sbjct: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS +K+ A K +K S NI G S VSSQK P K TSD+ D
Sbjct: 493 NKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEED 552
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S L IA E KDG + TVSS+K P LKA++ E+DSV NIA KDGEK+ VSS+K+P+L
Sbjct: 553 SVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSL 612
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
+AT+DE+DS NI E KDGE S VSSQK PALK T+DEEDSV IA E KDGEKS TV
Sbjct: 613 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV 672
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS K P LKATSDEKDS NI R KKDGE +RTV+S K LKA D+EDSV N+A K+
Sbjct: 673 SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKK 732
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
D + + VS +K+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 733 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 792
Query: 367 LSIAREEKDGE 377
+IA E KDG+
Sbjct: 793 SNIATEIKDGQ 803
Score = 328 bits (842), Expect = 4e-90
Identities = 207/399 (51%), Positives = 254/399 (63%), Gaps = 26/399 (6%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K+PA KATSD+KDS SNI K+G IS VSSQK P K TSDE+DSV IA E
Sbjct: 501 TVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARE 560
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS +K K +K S+LNIA G K+ VSS+K+P+ +ATSD+ D
Sbjct: 561 NKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKD 620
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NI E KDG VSSQK PALK T+DEEDSV IA E KDGEKS TVSS+K P L
Sbjct: 621 SFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 680
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+DE+DSVLNIA KDGEK+ TVSS KQPALKA D+EDSV +ATE KD + SGTV
Sbjct: 681 KATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTV 740
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
S +K+PALKATSD+KDS SNI E KDG+ S TV+S+K KATS ++DSV NIA +
Sbjct: 741 SCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIK 800
Query: 307 DGE--------------------------KTRRVSSRKKPALKATSDEKDSFSNITREKK 340
DG+ K+ VS +K+ A K +K S NI
Sbjct: 801 DGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRIT 860
Query: 341 DGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKS 379
G S T + P LKAT + ++SVL+ A + KD + S
Sbjct: 861 GGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 899
Score = 263 bits (671), Expect = 3e-70
Identities = 176/386 (45%), Positives = 226/386 (58%), Gaps = 26/386 (6%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K P KA+S +KDSV NIA K+G + VSS+K+P+ +ATSDEKDS SNI E
Sbjct: 569 TVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G+ S VS QK A K ++ S+L IA G KS TVSS+K P KATSD+ D
Sbjct: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S LNIA KDG + TVSS KQPALKA D+EDSV N+ATE KD + SGTVS QKQPAL
Sbjct: 689 SVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGT- 245
KAT+D++DSV NI TEIKDG++S TVSSQKQPA KAT+ ++DSVS IATEIKDG+ GT
Sbjct: 749 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
Query: 246 -------------------------VSSRKKPALKATSDEKDSFSNITREKKDGEISRTV 280
VS +K+ A K +K S NI G S T
Sbjct: 809 ILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTE 868
Query: 281 TSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKK 340
E LKAT + ++SVLN A +D + + + A + + + N + K
Sbjct: 869 YPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVK 928
Query: 341 DGETSRTVSSQKPPALKATSDEEDSV 366
+ SR + + S++ DS+
Sbjct: 929 NQIHSRDDLDDIIQSSQTVSEDGDSL 954
Score = 237 bits (604), Expect = 2e-62
Identities = 177/424 (41%), Positives = 227/424 (53%), Gaps = 40/424 (9%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVS----------------LLNIATRITGGG---KSG 108
+ +S +S K+I + + L A +T +S
Sbjct: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
Query: 109 TVS----SQKQPASKATSDKTDSALNI-ATEI----------KDGL------QCGTVSSQ 147
+S + ++ S+ +++ D+A I TE K+G Q VS +
Sbjct: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPE 199
Query: 148 KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGE 207
+ P T + D +S D S SS++ P T E D A KD
Sbjct: 200 QPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
Query: 208 KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNI 267
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SNI
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
Query: 268 TREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSD 327
E K G+ S TV+ +K + K ++ S+LNIA G K+ VSS+K+PA KATSD
Sbjct: 320 ATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
Query: 328 EKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQP 387
+ DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++
Sbjct: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 388 PGLK 391
P LK
Sbjct: 440 PALK 443
Score = 137 bits (345), Expect = 2e-32
Identities = 116/342 (33%), Positives = 156/342 (45%), Gaps = 40/342 (11%)
Query: 92 VSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 151
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
Query: 152 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE------------------ 193
L + D+V+ TE + +S +S P K +
Sbjct: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
Query: 194 -DSVLNIATEIKDGEKSE-----------TVSSQKQPALKATT--DEEDSVSIIATEIKD 239
D T+ K +SE T+S Q L A D+ ++ ++ + D
Sbjct: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVD 181
Query: 240 GE--------KSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKAT 291
E + VS + P T ++D S D S +SE+P T
Sbjct: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLT 241
Query: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
E D A ++D +VSS+K+PA KATSD+KDS SNI E K+G S TVSSQ
Sbjct: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
Query: 352 KPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
K PA KATSDE+DSV +IA E K G++S TVS ++ KV+
Sbjct: 302 KQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVI 343
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 642 bits (1656), Expect = 0.0
Identities = 343/384 (89%), Positives = 358/384 (93%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQP SKATSDKTDS
Sbjct: 324 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDS 383
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS
Sbjct: 444 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 503
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
SRKKPALKATSDEKDSFSNITREKKDGEISRTV+S+KP LKATSDEEDSVL+IAR ++D
Sbjct: 504 SRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKD 563
Query: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
GEK+R VSS + P LKAT DEKDS NI R KK GE +R VSS K PALKATSD+E+SV
Sbjct: 564 GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVP 623
Query: 368 SIAREEKDGEKSRTVSSEQPPGLK 391
++A E KD + S TVSS++ P LK
Sbjct: 624 NMATETKDEQISGTVSSQKQPALK 647
Score = 454 bits (1168), Expect = e-128
Identities = 269/423 (63%), Positives = 303/423 (71%), Gaps = 34/423 (8%)
Query: 3 PFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVS------------------- 43
P +VSSQKQPAEKATSD+KDSVSNIATEIKEG SGTVS
Sbjct: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLN 352
Query: 44 ---------------SQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIF 88
SQKQP KATSD+ DS NIATEIK+G Q GTVS QKQ A K
Sbjct: 353 IATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
Query: 89 KKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQK 148
++ S+ NIAT I G KSGTVSSQKQPA KAT+D+ DS LNIATEIKDG + TVSSQK
Sbjct: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQK 472
Query: 149 QPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEK 208
QPALKATTDEEDSVS IATEIKDGEKSGTVSS+K+PALKAT+DE+DS NI E KDGE
Sbjct: 473 QPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEI 532
Query: 209 SETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNIT 268
S TVSSQK PALKAT+DEEDSV IA E KDGEKS TVSS + P LKAT DEKDS NI
Sbjct: 533 SRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIA 592
Query: 269 REKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDE 328
R KK GE +R V+S K LKATSD+E+SV N+A +D + + VSS+K+PALKATSD+
Sbjct: 593 RGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDK 652
Query: 329 KDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPP 388
KDS SNI E KDG+ S TVSSQK A KATS ++DSV +IA E KDG+ TVSS++ P
Sbjct: 653 KDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQP 712
Query: 389 GLK 391
LK
Sbjct: 713 ALK 715
Score = 445 bits (1144), Expect = e-125
Identities = 256/388 (65%), Positives = 283/388 (72%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VS ++ P T D D +S + S SS++ P T E D S A
Sbjct: 195 NVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+ G VS QKQ A K K S+ NIAT I G SGTVSSQKQPA KATSD+ D
Sbjct: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NIATEIK+G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQP
Sbjct: 315 SVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPS 374
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+D+ DS LNIATEIKDG + TVSSQKQPALKATTDEEDSVS IATEIKDGEKSGTV
Sbjct: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS+K+PALKAT+DE+DS NI E KDGE S TV+S+K LKAT+DEEDSV IA +
Sbjct: 435 SSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIK 494
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
DGEK+ VSSRKKPALKATSDEKDSFSNITREKKDGE SRTVSSQKPPALKATSDEEDSV
Sbjct: 495 DGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSV 554
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLKVMK 394
LSIAREEKDGEKSRTVSSEQPPGLK +
Sbjct: 555 LSIAREEKDGEKSRTVSSEQPPGLKATR 582
Score = 439 bits (1129), Expect = e-123
Identities = 250/387 (64%), Positives = 298/387 (77%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQKQP KATSD DS NIATEIK+G GTVSSQKQPA KAT+DE+DSVSNIATE
Sbjct: 365 TVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
IK+G++SGTVS QKQ A K ++ S+LNIAT I G KS TVSSQKQPA KAT+D+ D
Sbjct: 425 IKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEED 484
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S IATEIKDG + GTVSS+K+PALKAT+DE+DS SNI E KDGE S TVSSQK PAL
Sbjct: 485 SVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPAL 544
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+DEEDSVL+IA E KDGEKS TVSS++ P LKAT DE+DS+ IA K GEK+ V
Sbjct: 545 KATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRV 604
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS K+PALKATSD+++S N+ E KD +IS TV+S+K LKATSD++DSV NI +
Sbjct: 605 SSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK 664
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
DG+++ VSS+K+ A KATS +KDS SNI E KDG+ TVSSQ+ PALKAT DE+DSV
Sbjct: 665 DGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSV 724
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393
+IARE KDGEKS TVS ++ KV+
Sbjct: 725 SNIAREIKDGEKSGTVSPQKQSAQKVI 751
Score = 415 bits (1066), Expect = e-116
Identities = 243/387 (62%), Positives = 288/387 (74%)
Query: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
C +VSSQKQPA KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DE+DSV NIA
Sbjct: 397 CGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIA 456
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
TEIK+G++S TVS QKQ A K ++ S+ IAT I G KSGTVSS+K+PA KATSD+
Sbjct: 457 TEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDE 516
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++ P
Sbjct: 517 KDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPP 576
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
LKAT DE+DS+LNIA K GEK+ VSS KQPALKAT+D+E+SV +ATE KD + SG
Sbjct: 577 GLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISG 636
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
TVSS+K+PALKATSD+KDS SNI E KDG+ S TV+S+K KATS ++DSV NIA
Sbjct: 637 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATE 696
Query: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEED 364
+DG+ VSS+++PALKAT DEKDS SNI RE KDGE S TVS QK A K ++
Sbjct: 697 IKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKV 756
Query: 365 SVLSIAREEKDGEKSRTVSSEQPPGLK 391
S+L+IA G KS T E P LK
Sbjct: 757 SLLNIATRITGGWKSGTEYPENLPTLK 783
Score = 308 bits (789), Expect = 6e-84
Identities = 191/360 (53%), Positives = 238/360 (66%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K+PA KATSD+KDS SNI E K+G IS TVSSQK PA KATSDE+DSV +IA E
Sbjct: 501 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIARE 560
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS ++ K +K SLLNIA G K+ VSS KQPA KATSDK +
Sbjct: 561 EKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKEN 620
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S N+ATE KD GTVSSQKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQ A
Sbjct: 621 SVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAW 680
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+ ++DSV NIATEIKDG+ TVSSQ+QPALKAT DE+DSVS IA EIKDGEKSGTV
Sbjct: 681 KATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTV 740
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
S +K+ A K +K S NI G S T E LKAT + ++SVLN A +
Sbjct: 741 SPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMK 800
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
D + + + A + + + N + K+ SR + + S++ DS+
Sbjct: 801 DVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 860
Score = 262 bits (669), Expect = 5e-70
Identities = 157/287 (54%), Positives = 188/287 (65%)
Query: 105 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 164
G+ VS ++ P T +D D L SS++ P T E D S
Sbjct: 191 GQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSK 250
Query: 165 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 224
A KD G VSSQKQPA KAT+D++DSV NIATEIK+G S TVSSQKQPA KAT+
Sbjct: 251 AAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATS 310
Query: 225 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEK 284
DE+DSVS IATEIK+G++SGTVS +K+ A K +K S NI G S TV+S+K
Sbjct: 311 DEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQK 370
Query: 285 PAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGET 344
KATSD+ DS LNIA +DG + VSS+K+PALKAT+DE+DS SNI E KDGE
Sbjct: 371 QPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEK 430
Query: 345 SRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
S TVSSQK PALKAT+DEEDSVL+IA E KDGEKS TVSS++ P LK
Sbjct: 431 SGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477
Score = 200 bits (508), Expect = 2e-51
Identities = 156/424 (36%), Positives = 200/424 (47%), Gaps = 74/424 (17%)
Query: 42 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 101
VSSQKQPA K TSD+ DSVSN ATEIK+ Q+SGTV P + + ++ T
Sbjct: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
Query: 102 TGGGKSGTVSSQKQPASKATSDKT-------------------DSALNIATEIKDGLQCG 142
+S +S P K S ++ D T+ K L+
Sbjct: 80 EFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALESE 139
Query: 143 -----------TVSSQKQPALKATTDEEDSVSNIATEIKDGEKSG----------TVSSQ 181
T+S Q L A + + + E ++ +K G VS +
Sbjct: 140 NISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPE 199
Query: 182 KQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGE 241
+ P T + D + D S SS++ P T E D S A KD
Sbjct: 200 QPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
Query: 242 KSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNI 301
G VSS+K+PA KATSD+KDS SNI E K+G IS TV+S+K KATSDE+DSV NI
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
Query: 302 ARGKEDGE----------------------------------KTRRVSSRKKPALKATSD 327
A ++G+ K+ VSS+K+P KATSD
Sbjct: 320 ATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSD 379
Query: 328 EKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQP 387
+ DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++
Sbjct: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 388 PGLK 391
P LK
Sbjct: 440 PALK 443
Score = 140 bits (353), Expect = 2e-33
Identities = 116/342 (33%), Positives = 155/342 (45%), Gaps = 40/342 (11%)
Query: 92 VSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 151
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQC 61
Query: 152 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE------------------ 193
L + D+V+ TE + +S +S P K +
Sbjct: 62 LNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYL 121
Query: 194 -DSVLNIATEIKDGEKSE-----------TVSSQKQPALKATTDEEDSVSIIATEIKDGE 241
D T+ K +SE T+S Q L A + + + E ++ +
Sbjct: 122 LDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVD 181
Query: 242 KSG----------TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKAT 291
K G VS + P T + D S D S +SE+P T
Sbjct: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLT 241
Query: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
E D A ++D +VSS+K+PA KATSD+KDS SNI E K+G S TVSSQ
Sbjct: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
Query: 352 KPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
K PA KATSDE+DSV +IA E K+G++S TVS ++ KV+
Sbjct: 302 KQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVI 343
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 640 bits (1652), Expect = 0.0
Identities = 352/418 (84%), Positives = 363/418 (86%), Gaps = 34/418 (8%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
K+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRI GGGKSGTVSSQKQPASKATSDKTDS
Sbjct: 324 KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
ATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+DEE SV IA E KDGEKS TVS
Sbjct: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISR----------------------------- 278
SRKKPA KATSDEKDSFSNITR KKDGEISR
Sbjct: 504 SRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563
Query: 279 -----TVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFS 333
TV+SEKP GLKA+SDE+DSVLNIARGK+ GEKT+RVSSRKKP+L+ATSDEKDSFS
Sbjct: 564 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 623
Query: 334 NITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
NITREKKDGE SR VSSQKPPALK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLK
Sbjct: 624 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 681
Score = 498 bits (1281), Expect = e-141
Identities = 277/385 (71%), Positives = 307/385 (79%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQKQPA KATSD DS NIATEIK+G GTVSSQKQPA KAT+DE+DSVSNIATE
Sbjct: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
IK+G++SGTVS QKQ A K +K S+ NIAT I G KSGTVSSQK PA ATSD+
Sbjct: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S L+IA E KDG + TVSS+K+PA KAT+DE+DS SNI KDGE S VSSQK P L
Sbjct: 485 SVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
K T+DEEDSVL IA E KDGEKS TVSS+K P LKA++DE+DSV IA K GEK+ V
Sbjct: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SSRKKP+L+ATSDEKDSFSNITREKKDGEISR V+S+KP LK TSDEEDSVL IAR +
Sbjct: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK 664
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
DGEK+R VSS K P LKATSDEKDS NI R KKDGE +RTVSSQKPP LKATSDEEDSV
Sbjct: 665 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSV 724
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
LSIARE KDGEKSRTVSSE+P GLK
Sbjct: 725 LSIARENKDGEKSRTVSSEKPSGLK 749
Score = 466 bits (1198), Expect = e-131
Identities = 268/423 (63%), Positives = 311/423 (73%), Gaps = 34/423 (8%)
Query: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
C +VSSQKQPA KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DEKDSVSNIA
Sbjct: 397 CGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIA 456
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
TEIK+G++SGTVS QK A ++ S+L+IA G KS TVSS+K+PASKATSD+
Sbjct: 457 TEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDE 516
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
DS NI KDG VSSQK P LK T+DEEDSV IA E KDGEKS TVSS+K P
Sbjct: 517 KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
LKA++DE+DSVLNIA K GEK++ VSS+K+P+L+AT+DE+DS S I E KDGE S
Sbjct: 577 GLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISR 636
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
VSS+K PALK TSDE+DS I RE KDGE SRTV+SEKP GLKATSDE+DSVLNIARG
Sbjct: 637 KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARG 696
Query: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKP----------- 353
K+DGEKTR VSS+K P LKATSDE+DS +I RE KDGE SRTVSS+KP
Sbjct: 697 KKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKD 756
Query: 354 -----------------------PALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGL 390
PALKATSDE+DSVL IARE+KDGEKSRTVSS++ P L
Sbjct: 757 SVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 816
Query: 391 KVM 393
K +
Sbjct: 817 KAI 819
Score = 442 bits (1137), Expect = e-124
Identities = 254/385 (65%), Positives = 280/385 (72%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VS ++ P T D+D +S + S SS++ P T E D S A
Sbjct: 195 NVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+ G VS QKQ A K K S+ NIAT I G SGTVSSQKQPA KATSD+ D
Sbjct: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NIATEIK G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA
Sbjct: 315 SVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS 374
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+D+ DS LNIATEIKDG + TVSSQKQPALKATTDEEDSVS IATEIKDGEKSGTV
Sbjct: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS+K+PALKAT+DEKDS SNI E KDGE S TV+S+KP L ATSDEE SVL+IAR +
Sbjct: 435 SSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENK 494
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
DGEK+R VSSRKKPA KATSDEKDSFSNITR KKDGE SR VSSQKPP LK TSDEEDSV
Sbjct: 495 DGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSV 554
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
L IARE KDGEKSRTVSSE+PPGLK
Sbjct: 555 LGIARENKDGEKSRTVSSEKPPGLK 579
Score = 435 bits (1118), Expect = e-122
Identities = 258/419 (61%), Positives = 296/419 (70%), Gaps = 34/419 (8%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQKQPA KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +IA E
Sbjct: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS +K+ A K +K S NI G S VSSQK P K TSD+ D
Sbjct: 493 NKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEED 552
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV------------------------ 162
S L IA E KDG + TVSS+K P LKA++DE+DSV
Sbjct: 553 SVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSL 612
Query: 163 ----------SNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETV 212
SNI E KDGE S VSSQK PALK T+DEEDSVL IA E KDGEKS TV
Sbjct: 613 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV 672
Query: 213 SSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
SS+K P LKAT+DE+DSV IA KDGEK+ TVSS+K P LKATSDE+DS +I RE K
Sbjct: 673 SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENK 732
Query: 273 DGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSF 332
DGE SRTV+SEKP+GLKATS E+DSVLNIARGK+ GEKT+RVSSRKKPALKATSDEKDS
Sbjct: 733 DGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSV 792
Query: 333 SNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
I REKKDGE SRTVSSQK PALKA D+EDSV ++A E+KD + S TVSS++ P LK
Sbjct: 793 LYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALK 851
Score = 405 bits (1042), Expect = e-113
Identities = 236/387 (60%), Positives = 280/387 (72%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K+PA KATSD+KDS SNI K+G IS VSSQK P K TSDE+DSV IA E
Sbjct: 501 TVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARE 560
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS +K K +K S+LNIA G K+ VSS+K+P+ +ATSD+ D
Sbjct: 561 NKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKD 620
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NI E KDG VSSQK PALK T+DEEDSV IA E KDGEKS TVSS+K P L
Sbjct: 621 SFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 680
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+DE+DSVLNIA KDGEK+ TVSSQK P LKAT+DEEDSV IA E KDGEKS TV
Sbjct: 681 KATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTV 740
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS K LKATS EKDS NI R KK GE ++ V+S K LKATSDE+DSVL IAR K+
Sbjct: 741 SSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKK 800
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
DGEK+R VSS+K+PALKA D++DS N+ EKKD + S TVSSQK PALKATSD++DSV
Sbjct: 801 DGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSV 860
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393
+I E KDG++S TVS ++ KV+
Sbjct: 861 SNIPTEIKDGQQSGTVSPQKQSAQKVI 887
Score = 319 bits (818), Expect = 2e-87
Identities = 193/345 (55%), Positives = 238/345 (68%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K P KA+SD+KDSV NIA K G + VSS+K+P+ +ATSDEKDS SNI E
Sbjct: 569 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G+ S VS QK A K ++ S+L IA G KS TVSS+K P KATSD+ D
Sbjct: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S LNIA KDG + TVSSQK P LKAT+DEEDSV +IA E KDGEKS TVSS+K L
Sbjct: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGL 748
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+ E+DSVLNIA K GEK++ VSS+K+PALKAT+DE+DSV IA E KDGEKS TV
Sbjct: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS+K+PALKA D++DS N+ EKKD +IS TV+S+K LKATSD++DSV NI +
Sbjct: 809 SSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK 868
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
DG+++ VS +K+ A K +K S NI G S TV Q
Sbjct: 869 DGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTVIRQ 913
Score = 237 bits (604), Expect = 2e-62
Identities = 177/424 (41%), Positives = 227/424 (53%), Gaps = 40/424 (9%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVS----------------LLNIATRITGGG---KSG 108
+ +S +S K+I + + L A +T +S
Sbjct: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
Query: 109 TVS----SQKQPASKATSDKTDSALNI-ATEI----------KDGL------QCGTVSSQ 147
+S + ++ S+ +++ D+A I TE K+G Q VS +
Sbjct: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPE 199
Query: 148 KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGE 207
+ P T + D +S D S SS++ P T E D A KD
Sbjct: 200 QPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
Query: 208 KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNI 267
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SNI
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
Query: 268 TREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSD 327
E K G+ S TV+ +K + K ++ S+LNIA G K+ VSS+K+PA KATSD
Sbjct: 320 ATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
Query: 328 EKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQP 387
+ DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++
Sbjct: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 388 PGLK 391
P LK
Sbjct: 440 PALK 443
Score = 137 bits (345), Expect = 2e-32
Identities = 116/342 (33%), Positives = 156/342 (45%), Gaps = 40/342 (11%)
Query: 92 VSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 151
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
Query: 152 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE------------------ 193
L + D+V+ TE + +S +S P K +
Sbjct: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
Query: 194 -DSVLNIATEIKDGEKSE-----------TVSSQKQPALKATT--DEEDSVSIIATEIKD 239
D T+ K +SE T+S Q L A D+ ++ ++ + D
Sbjct: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVD 181
Query: 240 GE--------KSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKAT 291
E + VS + P T ++D S D S +SE+P T
Sbjct: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLT 241
Query: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
E D A ++D +VSS+K+PA KATSD+KDS SNI E K+G S TVSSQ
Sbjct: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
Query: 352 KPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
K PA KATSDE+DSV +IA E K G++S TVS ++ KV+
Sbjct: 302 KQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVI 343
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 535 bits (1378), Expect = e-152
Identities = 306/418 (73%), Positives = 320/418 (76%), Gaps = 68/418 (16%)
Query: 42 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 101
+S QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSA KVIFKKKVSLLNIATRI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 102 TGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 161
GGGKSGTVSSQKQPASK SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 162 VSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 221
VSNIATEIKDGEKSGTVSSQK+PALKAT+DE+DS NI E KDGE S TVSSQK PALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 222 ATTDEEDSVSIIATEIKDGEKSGTVS---------------------------------- 247
AT+ +EDSV IA E KDGEKS TVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEI------------------------------- 276
SRKKPALKATSDEKDSFSNITR KKDGEI
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 277 ---SRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFS 333
SRTV+SEKP GLKA+SDE+DSVLNIARGK+ GEKT+RVSSRKKP+L+ATSDEKDSFS
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 334 NITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
NITREKKDGE SR VSSQKPPALK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLK
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 509
Score = 463 bits (1191), Expect = e-130
Identities = 262/389 (67%), Positives = 299/389 (76%)
Query: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
C +VSSQKQ A KAT+D++ SVSNIATEIK+G SGTVSSQK+PA KATSDEKDS SNI
Sbjct: 191 CGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNIT 250
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
E K+G+ S TVS QK A K K+ S+LNIA G KS TVS + P KAT D+
Sbjct: 251 REKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDE 310
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
DS LNIA K+G + VSS+K+PALKAT+DE+DS SNI KDGE S VSSQK P
Sbjct: 311 KDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPP 370
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
LK T+DEEDSVL IA E KDGEKS TVSS+K P LKA++DE+DSV IA K GEK+
Sbjct: 371 TLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTK 430
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
VSSRKKP+L+ATSDEKDSFSNITREKKDGEISR V+S+KP LK TSDEEDSVL IAR
Sbjct: 431 RVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARE 490
Query: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEED 364
+DGEK+R VSS K P LKATSDEKDS NI R KKDGE +RTVSS+K PALKATSDE+D
Sbjct: 491 NKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKD 550
Query: 365 SVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
SVL IARE+KDGEKSRTVSS++ P LK +
Sbjct: 551 SVLYIAREKKDGEKSRTVSSQKQPALKAI 579
Score = 404 bits (1037), Expect = e-112
Identities = 245/419 (58%), Positives = 284/419 (67%), Gaps = 34/419 (8%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQK+PA KATSD+KDS SNI E K+G IS TVSSQK PA KATS ++DSV NIA E
Sbjct: 227 TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIARE 286
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS + K +K SLLNIA G K+ VSS+K+PA KATSD+ D
Sbjct: 287 KKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKD 346
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NI KDG VSSQK P LK T+DEEDSV IA E KDGEKS TVSS+K P L
Sbjct: 347 SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 406
Query: 187 KATTDEEDSVLNIAT----------------------------------EIKDGEKSETV 212
KA++DE+DSVLNIA E KDGE S V
Sbjct: 407 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 466
Query: 213 SSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
SSQK PALK T+DEEDSV IA E KDGEKS TVSS K P LKATSDEKDS NI R KK
Sbjct: 467 SSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKK 526
Query: 273 DGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSF 332
DGE +RTV+S K LKATSDE+DSVL IAR K+DGEK+R VSS+K+PALKA D++DS
Sbjct: 527 DGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSV 586
Query: 333 SNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
N+ EKKD + S TVSSQK PALKATSD++DSV +I E KDG++S TVSS++ P K
Sbjct: 587 PNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWK 645
Score = 384 bits (987), Expect = e-107
Identities = 229/387 (59%), Positives = 274/387 (70%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VS + P KAT D+KDS+ NIA K G + VSS+K+PA KATSDEKDS SNI
Sbjct: 295 TVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRG 354
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G+ S VS QK K ++ S+L IA G KS TVSS+K P KA+SD+ D
Sbjct: 355 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 414
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S LNIA K G + VSS+K+P+L+AT+DE+DS SNI E KDGE S VSSQK PAL
Sbjct: 415 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 474
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
K T+DEEDSVL IA E KDGEKS TVSS+K P LKAT+DE+DSV IA KDGEK+ TV
Sbjct: 475 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 534
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SSRKKPALKATSDEKDS I REKKDGE SRTV+S+K LKA D+EDSV N+A K+
Sbjct: 535 SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKK 594
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
D + + VSS+K+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 595 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 654
Query: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393
+IA E KDG+ TVS ++ KV+
Sbjct: 655 SNIATEIKDGQIRGTVSPQKQSAQKVI 681
Score = 367 bits (943), Expect = e-102
Identities = 217/374 (58%), Positives = 265/374 (70%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSS+K+PA KATSD+KDS SNI K+G IS VSSQK P K TSDE+DSV IA E
Sbjct: 330 VSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 389
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
K+G++S TVS +K K +K S+LNIA G K+ VSS+K+P+ +ATSD+ DS
Sbjct: 390 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 449
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
NI E KDG VSSQK PALK T+DEEDSV IA E KDGEKS TVSS+K P LK
Sbjct: 450 FSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 509
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
AT+DE+DSVLNIA KDGEK+ TVSS+K+PALKAT+DE+DSV IA E KDGEKS TVS
Sbjct: 510 ATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVS 569
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
S+K+PALKA D++DS N+ EKKD +IS TV+S+K LKATSD++DSV NI +D
Sbjct: 570 SQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD 629
Query: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
G+++ VSS+K+PA KATS +KDS SNI E KDG+ TVS QK A K ++ S+L
Sbjct: 630 GQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLL 689
Query: 368 SIAREEKDGEKSRT 381
+IA G KS T
Sbjct: 690 NIATRITGGGKSGT 703
Score = 302 bits (774), Expect = 3e-82
Identities = 180/305 (59%), Positives = 220/305 (72%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K P KA+SD+KDSV NIA K G + VSS+K+P+ +ATSDEKDS SNI E
Sbjct: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G+ S VS QK A K ++ S+L IA G KS TVSS+K P KATSD+ D
Sbjct: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S LNIA KDG + TVSS+K+PALKAT+DE+DSV IA E KDGEKS TVSSQKQPAL
Sbjct: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KA D+EDSV N+ATE KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTV
Sbjct: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
SS+K+PA KATS +KDS SNI E KDG+I TV+ +K + K ++ S+LNIA
Sbjct: 637 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRIT 696
Query: 307 DGEKT 311
G K+
Sbjct: 697 GGGKS 701
Score = 264 bits (674), Expect = 1e-70
Identities = 147/217 (67%), Positives = 170/217 (78%)
Query: 178 VSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEI 237
+S QKQPA KAT+DE+DSV NIATEIK+G++S TVS QKQ A K ++ S+ IAT I
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 238 KDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDS 297
G KSGTVSS+K+PA K SD+ DS N E KDG TV+S+K LKAT+DEE S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 298 VLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALK 357
V NIA +DGEK+ VSS+KKPALKATSDEKDSFSNITREKKDGE SRTVSSQKPPALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 358 ATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVMK 394
ATS +EDSVL+IARE+KDGEKSRTVS +QPPGLK +
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATR 308
Score = 219 bits (559), Expect = 3e-57
Identities = 130/205 (63%), Positives = 150/205 (73%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSS+K P KATSD+KDSV NIA K+G + TVSS+K+PA KATSDEKDSV IA E
Sbjct: 499 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIARE 558
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS QKQ A K I K+ S+ N+AT SGTVSSQKQPA KATSDK D
Sbjct: 559 KKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKD 618
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NI TEIKDG Q GTVSSQKQPA KAT+ ++DSVSNIATEIKDG+ GTVS QKQ A
Sbjct: 619 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQ 678
Query: 187 KATTDEEDSVLNIATEIKDGEKSET 211
K ++ S+LNIAT I G KS T
Sbjct: 679 KVIFKKKVSLLNIATRITGGGKSGT 703
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 532 bits (1370), Expect = e-151
Identities = 296/384 (77%), Positives = 320/384 (83%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
+S QKQ AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
KEGQQSGTVSPQKQSA KVIFKKKVSLLNIATRI GGGKSGTVSSQKQPASK SDKTDS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
ALN ATEIKDGLQCGTVSSQKQ ALKATTDEE SVSNIATEIKDGEKSGTVSSQK+PALK
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
AT+DE+DS NI E KDGE S TVSSQK PALKAT+ +EDSV IA E KDGEKS TVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
+ P LKAT DEKDS NI R KKDGE +R V+S K LKATSD+EDSV N+A +D
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
Query: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
+ + VS +K+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
Query: 368 SIAREEKDGEKSRTVSSEQPPGLK 391
+IA E KDG+ TVSS++ P LK
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALK 406
Score = 425 bits (1092), Expect = e-119
Identities = 245/391 (62%), Positives = 289/391 (73%)
Query: 3 PFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 62
P +VSSQKQPAEKATSD+KDSVSNIATEIKEG SGTVS QKQ A+K +K S+ N
Sbjct: 52 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLN 111
Query: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
IAT I G +SGTVS QKQ A K K S LN AT I G + GTVSSQKQ A KAT+
Sbjct: 112 IATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATT 171
Query: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
D+ S NIATEIKDG + GTVSSQK+PALKAT+DE+DS SNI E KDGE S TVSSQK
Sbjct: 172 DEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 231
Query: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
PALKAT+ +EDSVLNIA E KDGEKS TVS ++ P LKAT DE+DS+ IA KDGEK
Sbjct: 232 PPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEK 291
Query: 243 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIA 302
+ VSS K+P+LKATSD++DS N+ E KD +IS TV+ +K LKATSD++DSV NI
Sbjct: 292 TRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIP 351
Query: 303 RGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDE 362
+DG+++ VSS+K+PA KATS +KDS SNI E KDG+ TVSSQ+ PALK T DE
Sbjct: 352 TEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDE 411
Query: 363 EDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
+DSV +IARE KDGEKS TVS ++ KV+
Sbjct: 412 KDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442
Score = 344 bits (883), Expect = 7e-95
Identities = 201/341 (58%), Positives = 243/341 (71%)
Query: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
C +VSSQKQ A KAT+D++ SVSNIATEIK+G SGTVSSQK+PA KATSDEKDS SNI
Sbjct: 156 CGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNIT 215
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
E K+G+ S TVS QK A K K+ S+LNIA G KS TVS ++ P KAT D+
Sbjct: 216 REKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDE 275
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
DS LNIA KDG + VSS KQP+LKAT+D+EDSV N+ATE KD + SGTVS QKQP
Sbjct: 276 KDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQP 335
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
ALKAT+D++DSV NI TEIKDG++S TVSSQKQPA KAT+ ++DSVS IATEIKDG+ G
Sbjct: 336 ALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRG 395
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
TVSS+++PALK T DEKDS SNI RE KDGE S TV+ +K + K ++ S+LNIA
Sbjct: 396 TVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATR 455
Query: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETS 345
G K+ LKAT + KDS N + K+ +TS
Sbjct: 456 ITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS 496
Score = 311 bits (797), Expect = 7e-85
Identities = 174/251 (69%), Positives = 200/251 (79%)
Query: 144 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 203
+S QKQ A KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DE+DSV NIATEI
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 204 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDS 263
K+G++S TVS QKQ A K ++ S+ IAT I G KSGTVSS+K+PA K SD+ DS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 264 FSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALK 323
N E KDG TV+S+K LKAT+DEE SV NIA +DGEK+ VSS+KKPALK
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 324 ATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVS 383
ATSDEKDSFSNITREKKDGE SRTVSSQKPPALKATS +EDSVL+IARE+KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 384 SEQPPGLKVMK 394
EQPPGLK +
Sbjct: 263 FEQPPGLKATR 273
Score = 307 bits (786), Expect = 1e-83
Identities = 194/371 (52%), Positives = 237/371 (63%), Gaps = 13/371 (3%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQK+PA KATSD+KDS SNI E K+G IS TVSSQK PA KATS ++DSV NIA E
Sbjct: 192 TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIARE 251
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+G++S TVS ++ K +K SLLNIA G K+ VSS KQP+ KATSDK D
Sbjct: 252 KKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKED 311
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S N+ATE KD GTVS QKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQPA
Sbjct: 312 SVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAW 371
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
KAT+ ++DSV NIATEIKDG+ TVSSQ++PALK T DE+DSVS IA EIKDGEKSGTV
Sbjct: 372 KATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTV 431
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
S +K+ A K +K S NI G S T E LKAT + +DSVLN A
Sbjct: 432 SPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTA---- 487
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
++ K +T E+D E+K E Q + + D +D +
Sbjct: 488 ---------TKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDII 538
Query: 367 LSIAREEKDGE 377
S +DG+
Sbjct: 539 QSSQTVSEDGD 549
Score = 237 bits (605), Expect = 1e-62
Identities = 147/292 (50%), Positives = 185/292 (63%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VS ++ P KAT D+KDS+ NIA K+G + VSS KQP+ KATSD++DSV N+ATE
Sbjct: 260 TVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATE 319
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KATS K D
Sbjct: 320 TKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 379
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S NIATEIKDG GTVSSQ++PALK T DE+DSVSNIA EIKDGEKSGTVS QKQ A
Sbjct: 380 SVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 439
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
K ++ S+LNIAT I G KS T + LKAT + +DSV AT++K+ + S
Sbjct: 440 KVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA 499
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSV 298
+ A + + + N + K+ SR + + S++ DS+
Sbjct: 500 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 551
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 255 bits (651), Expect = 6e-68
Identities = 158/298 (53%), Positives = 191/298 (64%)
Query: 1 MYPFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV 60
M PF FSVSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV
Sbjct: 1 MNPFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSV 60
Query: 61 SNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKA 120
N+ATE K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KA
Sbjct: 61 PNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKA 120
Query: 121 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 180
TS K DS NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS
Sbjct: 121 TSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP 180
Query: 181 QKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDG 240
QKQ A K ++ S+LNIAT I G KS T + P LKAT + ++SV AT++KD
Sbjct: 181 QKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV 240
Query: 241 EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSV 298
+ S + A + + + N + K+ SR + + S++ DS+
Sbjct: 241 QTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
Score = 241 bits (616), Expect = 6e-64
Identities = 139/237 (58%), Positives = 171/237 (72%)
Query: 109 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 168
+VSS+K KATSD+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 169 IKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEED 228
KD + SGTVSSQKQPALKAT+D++DSV NI TEIKDG++S TVSSQKQPA KAT+ ++D
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 229 SVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGL 288
SVS IATEIKDG+ GTVSS+++PALKAT DEKDS SNI RE KDGE S TV+ +K +
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 289 KATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETS 345
K ++ S+LNIA G K+ P LKAT + K+S N + KD +TS
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
Score = 234 bits (598), Expect = 8e-62
Identities = 147/292 (50%), Positives = 185/292 (63%)
Query: 75 TVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATE 134
+VS +K S K +K S+LNIA G K+ VSS KQPA KATSDK +S N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 135 IKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEED 194
KD GTVSSQKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQPA KAT+ ++D
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 195 SVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPAL 254
SV NIATEIKDG+ TVSSQ+QPALKAT DE+DSVS IA EIKDGEKSGTVS +K+ A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 255 KATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRV 314
K +K S NI G S T E LKAT + ++SVLN A +D + +
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 315 SSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
+ A + + + N + K+ SR + + S++ DS+
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
Score = 232 bits (592), Expect = 4e-61
Identities = 135/237 (56%), Positives = 170/237 (71%)
Query: 143 TVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATE 202
+VSS+K LKAT+DE+DSV NIA K GEK+ VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 203 IKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKD 262
KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTVSS+K+PA KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 263 SFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPAL 322
S SNI E KDG+I TV+S++ LKAT DE+DSV NIAR +DGEK+ VS +K+ A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 323 KATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKS 379
K +K S NI G S T + P LKAT + ++SVL+ A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
Score = 213 bits (542), Expect = 2e-55
Identities = 126/215 (58%), Positives = 153/215 (71%)
Query: 177 TVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATE 236
+VSS+K LKAT+DE+DSVLNIA K GEK+ VSS KQPALKAT+D+E+SV +ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 237 IKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEED 296
KD + SGTVSS+K+PALKATSD+KDS SNI E KDG+ S TV+S+K KATS ++D
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 297 SVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPAL 356
SV NIA +DG+ VSS+++PALKAT DEKDS SNI RE KDGE S TVS QK A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 357 KATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
K ++ S+L+IA G KS T E P LK
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLK 221
Score = 187 bits (475), Expect = 1e-47
Identities = 106/183 (57%), Positives = 135/183 (73%)
Query: 211 TVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITRE 270
+VSS+K LKAT+DE+DSV IA K GEK+ VSS K+PALKATSD+++S N+ E
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 271 KKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKD 330
KD +IS TV+S+K LKATSD++DSV NI +DG+++ VSS+K+PA KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 331 SFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGL 390
S SNI E KDG+ TVSSQ+ PALKAT DE+DSV +IARE KDGEKS TVS ++
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 391 KVM 393
KV+
Sbjct: 187 KVI 189
>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 753
Score = 113 bits (283), Expect = 3e-25
Identities = 65/115 (56%), Positives = 80/115 (69%)
Query: 144 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 203
VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D++DSV N ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 204 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATS 258
KD +KS TV + L + D+V+ TE + +S +S P K S
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 111 bits (278), Expect = 1e-24
Identities = 65/115 (56%), Positives = 76/115 (66%)
Query: 107 SGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 166
S VSSQKQPA KATS K DS NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 167 TEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 221
TEIKD +KSGTV + L + D+V TE + +SE +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 105 bits (263), Expect = 6e-23
Identities = 58/98 (59%), Positives = 71/98 (72%)
Query: 175 SGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIA 234
S VSSQKQPALKAT+ +EDS+ NIATEIKDG+KS TVSSQKQPALK T+D++DSVS A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 235 TEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
TEIKD +KSGTV + L + D+ + E +
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENE 682
Score = 100 bits (250), Expect = 2e-21
Identities = 54/71 (76%), Positives = 60/71 (84%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
VSSQKQPA KATS +DS+SNIATEIK+G SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 68 KEGQQSGTVSP 78
K+ Q+SGTV P
Sbjct: 648 KDEQKSGTVLP 658
Score = 93.6 bits (231), Expect = 3e-19
Identities = 58/118 (49%), Positives = 71/118 (60%)
Query: 209 SETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNIT 268
S VSSQKQPALKAT+ +EDS+S IATEIKDG+KSGTVSS+K+PALK TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 269 REKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATS 326
E KD + S TV L + D+V E ++ +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 83.6 bits (205), Expect = 3e-16
Identities = 53/115 (46%), Positives = 66/115 (57%)
Query: 39 SGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 98
S VSSQKQPA KATS ++DS+SNIATEIK+GQ+SGTVS QKQ A K K S+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 99 TRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALK 153
T I KSGTV + + + D+ TE + L+ +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 83.6 bits (205), Expect = 3e-16
Identities = 54/115 (46%), Positives = 64/115 (55%)
Query: 73 SGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIA 132
S VS QKQ A K K+ S+ NIAT I G KSGTVSSQKQPA K TSDK DS N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 133 TEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
TEIKD + GTV + L + D+V+ TE + +S +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 83.2 bits (204), Expect = 4e-16
Identities = 45/69 (65%), Positives = 54/69 (78%)
Query: 314 VSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREE 373
VSS+K+PALKATS ++DS SNI E KDG+ S TVSSQK PALK TSD++DSV + A E
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 374 KDGEKSRTV 382
KD +KS TV
Sbjct: 648 KDEQKSGTV 656
Score = 75.9 bits (185), Expect = 6e-14
Identities = 47/117 (40%), Positives = 65/117 (55%)
Query: 277 SRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNIT 336
S V+S+K LKATS +EDS+ NIA +DG+K+ VSS+K+PALK TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 337 REKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
E KD + S TV L + D+V E + +S +S P K++
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKII 701
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/118 (39%), Positives = 65/118 (55%)
Query: 243 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIA 302
S VSS+K+PALKATS ++DS SNI E KDG+ S TV+S+K LK TSD++DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 303 RGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATS 360
+D +K+ V + L + D+ + E + S +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/86 (39%), Positives = 46/86 (53%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 621 TVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKV 92
+ +S +S K+I + +
Sbjct: 681 NEFSLESEIISKLYIPKRKIISPRSI 706
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 60.1 bits (144), Expect = 3e-09
Identities = 93/400 (23%), Positives = 153/400 (38%), Gaps = 41/400 (10%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEG-----PISGTVSSQKQPAEKATSDEKDSVSNI 63
+ + Q E+ T +++ + +EG G ++ PAE+A S EK++ S +
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 64 ATEIKEGQQSGTVSPQKQSAWKVIF----KKKVSLLNIATRITGGGKSGTVSSQKQPASK 119
E K ++ SP+K+ A +K S + KS K PA
Sbjct: 521 KEEAKSPAEA--KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 120 ATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVS 179
+ +K S E K + + K P +E S + + +K+ KS
Sbjct: 579 KSPEKAKSPAK--EEAKSPAEAKSPEKAKSP----VKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 180 SQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQ--KQPALKATTDEEDSVSIIATEI 237
+ A T +E S + K EK E S + K P E + S + E
Sbjct: 633 KSPEKAKSPTKEEAKS----PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 238 KDGEKS-GTVSSRKKPALKATSDEKD-------SFSNITREKKDGEISRT-VTSEKPAGL 288
K EK+ V K KA S K+ + S + E K E +++ V E +
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 289 KATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTV 348
KA S E+ L++ K KT + PA K K S + E K E +++
Sbjct: 749 KAKSPEKAKTLDV---KSPEAKTPAKEEARSPADKFPEKAK---SPVKEEVKSPEKAKSP 802
Query: 349 SSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPP 388
+ A + +++ V S +EE EK + V ++PP
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEE---EKPQEVKVKEPP 839
Score = 58.5 bits (140), Expect = 1e-08
Identities = 87/378 (23%), Positives = 148/378 (39%), Gaps = 37/378 (9%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQ---KQPAEKATSDEKDSVSNIATEIKEGQQ 72
EKA S +K+ + E + P+ S K P + + + S + E K ++
Sbjct: 650 EKAKSPEKEEAKS--PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEK 707
Query: 73 SGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIA 132
+ SP K+ A +K S + + KS K P KA S + L++
Sbjct: 708 AK--SPVKEEAKSP--EKAKSPVKEEAKTPEKAKSPVKEEAKSP-EKAKSPEKAKTLDVK 762
Query: 133 -----TEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
T K+ + + A +E S + +K+ K+ K+ +K
Sbjct: 763 SPEAKTPAKEEAR-SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
+ EE+ E+K E + +K PA T +++DS A + K+ K V
Sbjct: 822 SPVKEEEK----PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK-KEAPKP-KVE 875
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTV-TSEKPAGLKATSDEEDSVLNIARGKE 306
+K+PA+ EK S + +K++ E + V T EK A K E+ A+ KE
Sbjct: 876 EKKEPAV-----EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED------AKPKE 924
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
E ++ K + EK EKKD + + ++ P +A + E+D
Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEK---KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 367 LSIAREEKDGEKSRTVSS 384
LS + EK+ SS
Sbjct: 982 LSKEPSKPKAEKAEKSSS 999
Score = 56.2 bits (134), Expect = 5e-08
Identities = 83/404 (20%), Positives = 148/404 (36%), Gaps = 35/404 (8%)
Query: 12 KQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQ 71
K PAE + + +++ S + E S K P E + +++++ S + E
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 72 QSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNI 131
+S K A +K S + + KS K PA + +K S
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Query: 132 ATEIKDGL------QCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPA 185
+ + + + K P E + S + E K EK+ K P
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA------KSPV 698
Query: 186 LKATTDEEDSVLNIATEIKDGEKSETVSSQ--KQPALKATTDEEDSVSIIATEIKDGEKS 243
+ E + + E K EK+++ + K P + +E++ S + K EK+
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS--PEKAKSPEKA 756
Query: 244 GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIAR 303
T+ + A +E S ++ EK + V S + A D + I +
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816
Query: 304 GKE------DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRT---------V 348
+E + EK + V ++ P K +EK + T EKKD + V
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPP--KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874
Query: 349 SSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKV 392
+K PA++ +E V + E +D +K T E P ++V
Sbjct: 875 EEKKEPAVE--KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV 916
Score = 42.0 bits (97), Expect = 0.001
Identities = 78/347 (22%), Positives = 143/347 (41%), Gaps = 53/347 (15%)
Query: 71 QQSGTVSPQKQSAWKVIFKKKVS--LLNIATRITGGGKSGTVSSQK---------QPASK 119
Q SG Q Q+ + K V+ L I ++ G T+ S++ A+K
Sbjct: 246 QGSGAAQAQMQAETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAK 305
Query: 120 ATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVS 179
+D SA TE + LQ T + ALK+T +DS+ +E++D ++ ++
Sbjct: 306 VNTDAMRSAQEEITEYRRQLQARTTELE---ALKST---KDSLERQRSELEDRHQAD-IA 358
Query: 180 SQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPAL----KATTDEEDSVSI--I 233
S ++ + + ++ +A ++++ + V + K EE + I
Sbjct: 359 SYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPI 418
Query: 234 ATEIKDG-EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATS 292
+ +G K +VS+ +K S+EK + + +K+ I T E + T
Sbjct: 419 PFSLPEGLPKIPSVSTH----IKVKSEEK--IKVVEKSEKETVIVEEQTEETQVTEEVTE 472
Query: 293 DEEDSVLNIARGKEDGEKTRRVS-----SRKKPALKATSDEKDSFSNITREKKDGETSRT 347
+EE +E+G + ++ PA +A S EK++ S + E K
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS------ 526
Query: 348 VSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQ---PPGLK 391
PA +A S E++ S A E K EK+++ + E+ PP K
Sbjct: 527 ------PA-EAKSPEKEEAKSPA-EVKSPEKAKSPAKEEAKSPPEAK 565
Score = 35.8 bits (81), Expect = 0.070
Identities = 53/221 (23%), Positives = 83/221 (37%), Gaps = 55/221 (24%)
Query: 11 QKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEG 70
+K PA T + KDS A + KE P V +K+PA EK S + + +E
Sbjct: 845 EKAPATPKTEEKKDSKKEEAPK-KEAP-KPKVEEKKEPAV-----EKPKESKVEAKKEEA 897
Query: 71 QQSGTV-SPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSAL 129
+ V +P+K++ KV K+ K T ++K+P
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAK-----------PKEKTEVAKKEPDD----------- 935
Query: 130 NIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKAT 189
+ K+P+ A E A E KD ++ +++P +A
Sbjct: 936 ---------------AKAKEPSKPAEKKEA------APEKKDTKEEKAKKPEEKPKTEAK 974
Query: 190 TDEEDSVLNIATEIKDGEKSETVSSQKQ----PALKATTDE 226
E+D L+ EK+E SS Q P KAT D+
Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 30.4 bits (67), Expect = 2.9
Identities = 26/125 (20%), Positives = 48/125 (38%), Gaps = 4/125 (3%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+V K+ +A ++ + + T KE P V +P EK +K+ A E
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKA----TS 122
+ + +P+K+ + KK + K+ + K A KA ++
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000
Query: 123 DKTDS 127
D+ DS
Sbjct: 1001 DQKDS 1005
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 54.3 bits (129), Expect = 2e-07
Identities = 74/389 (19%), Positives = 137/389 (35%), Gaps = 25/389 (6%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
S SS ++ +S D DS + +++ + S + +S +SD DS S+ +
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS-SDSSDS 622
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
+ +S + S S K S N + S + +S S +SD +D
Sbjct: 623 KSDSSKSESDSSDSDS------KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 127 SALNI----ATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
S+ + +++ D S + + +D DS + + D + S + S
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
++D DS + + S++ +S ++D DS + +
Sbjct: 737 SSNSSDSSDSSDS----SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 243 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIA 302
+ SS + ++ S S+ + + S + S + +SD DS +
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS----S 848
Query: 303 RGKEDGEKTRRVSSRKKPALKA-----TSDEKDSF-SNITREKKDGETSRTVSSQKPPAL 356
G + R SS + + +SD DS SN + D S S
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908
Query: 357 KATSDEEDSVLSIAREEKDGEKSRTVSSE 385
+SD DS S E + SS+
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Score = 53.5 bits (127), Expect = 3e-07
Identities = 55/265 (20%), Positives = 103/265 (38%), Gaps = 12/265 (4%)
Query: 103 GGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV 162
G G +G + K + K SD +DS + ++ D SS + ++ + DS
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD----SSDSDSSDSNSSSDSDSS 583
Query: 163 SNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKA 222
+ +++ D + S + +S ++D DS + + D KSE+ SS +
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS-SDSSDSKSDSSKSESDSSDSD----S 638
Query: 223 TTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITR--EKKDGEISRTV 280
+D DS S +++ D S S+ + + S + S S+ + + D S
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698
Query: 281 TSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKK 340
+ + + SD DS + D + + S +SD DS SN +
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSD 757
Query: 341 DGETSRTVSSQKPPALKATSDEEDS 365
++S + S +SD +S
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNS 782
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/291 (19%), Positives = 108/291 (37%), Gaps = 16/291 (5%)
Query: 102 TGGGKSGTVSSQKQPASKAT--SDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEE 159
+G GKS + S +S ++ SD +DS + + D + SS + ++
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS-DSSDSSN 600
Query: 160 DSVSNIATEIKDGEKSGTVSSQKQPALKATTDEED-------SVLNIATEIKDGEKSETV 212
S S+ +++ D S S K + K+ +D D S N + + + S++
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 213 SSQKQPALKATTDEEDSVSII----ATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNIT 268
+S ++D DS S +++ D S S + + SD DS +
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 269 REKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDE 328
D + S + S + +SD DS + + D + S + + S +
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDS--SNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Query: 329 KDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKS 379
+ S+ ++S + +S +SD DS S + D S
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/386 (17%), Positives = 140/386 (36%), Gaps = 15/386 (3%)
Query: 7 SVSSQKQPAEKATSDDKDSV----SNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVS- 61
S SS ++ + SD DS S+ +++ + S S K + K+ SD DS S
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSK 639
Query: 62 --NIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASK 119
+ + + + S S+ + ++ S + S S
Sbjct: 640 SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699
Query: 120 ATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVS 179
+SD +DS+ + +++ D + S ++D DS SN + + S +
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDS----SNSSDSSDS-SNSSDSSDSSDSSNSSD 754
Query: 180 SQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKD 239
S ++D DS + + SS + ++ + S S +++ D
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Query: 240 GEKSGTVSSRKKPALKATSDEKDSF-SNITREKKDGEISRTVTSEKPAGLKATSDEEDSV 298
S + +S +SD +S S+ + + DG S + + +SD DS
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS- 873
Query: 299 LNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKA 358
+ + D + S+ + + S + DS + ++ + SS+ +
Sbjct: 874 -SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 359 TSDEEDSVLSIAREEKDGEKSRTVSS 384
++ + S S + + D S S+
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSN 958
Score = 45.4 bits (106), Expect = 9e-05
Identities = 64/376 (17%), Positives = 134/376 (35%), Gaps = 22/376 (5%)
Query: 10 SQKQPAEKATSDDK----DSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA- 64
S K ++ + SD K DS S+ +++ + S S+ ++ + S + S S+ +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 65 -TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSD 123
++ + S S S+ S + + + S + S S +SD
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 124 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 183
+DS+ + + + SS + ++ S SN ++ D S S
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 184 PALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS 243
++D DS + S++ SS + ++ + S S +++ D
Sbjct: 806 -----SSDSSDS----------SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850
Query: 244 GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIAR 303
S + +SD DS S+ + + S + S + +S+ DS + +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDS-SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Query: 304 GKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEE 363
D + S + + + + SN + ++S + S +SD
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 364 DSVLSIAREEKDGEKS 379
DS S + + + S
Sbjct: 970 DSNSSDSSDSSNSSDS 985
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/356 (14%), Positives = 126/356 (35%), Gaps = 6/356 (1%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S+ +E + S D + S+ + S + +S +S+ DS + +++
Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Query: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
+ S S S+ + + + S + S S +SD +DS+
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 129 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 188
+ + + SS + ++ + S S+ +++ D +S S + +
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 189 TTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSS 248
+ + + + + S++ +S ++D DS + +++ D +S S
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN--SSDSSDSSESSDSSD 1155
Query: 249 RKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG 308
+ + S + S+ + + S + S + +SD DS + +
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS----SDSSDSS 1211
Query: 309 EKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEED 364
+ + S +SD +S + ++ + SS + +TSD D
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267
Score = 43.9 bits (102), Expect = 3e-04
Identities = 69/387 (17%), Positives = 136/387 (35%), Gaps = 20/387 (5%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
S +S ++ + S D SN + S + S +SD DS + ++
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS--SD 775
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
+ S + S+ N + S + SS +S + SD +D
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS-SDSSD 834
Query: 127 SA----LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV-SNIATEIKDGEKSGTVSSQ 181
S+ + +++ DG + + ++D DS S+ +++ D +S S
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 182 KQPALKATTDEEDSVLNIATEIKDGEKS-----ETVSSQKQPALKATTDEEDSVSIIATE 236
+ + +D DS + +++ D S + SS + ++ + S S ++
Sbjct: 895 SDSSNSSDSDSSDS--SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 237 IKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEED 296
D S S+ + +SD DS SN + + S + S + +SD D
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 297 SVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPAL 356
S + + + S +SD DS + ++ + SS +
Sbjct: 1012 S----SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 357 KATSDEEDSVLSIAREEKDGEKSRTVS 383
++ + S S + E D S S
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Score = 42.7 bits (99), Expect = 6e-04
Identities = 67/386 (17%), Positives = 129/386 (33%), Gaps = 16/386 (4%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S ++ + S D + SN + S + +S +SD S S+ ++
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
+ S S S+ S + + R S + S S +SD +DS
Sbjct: 831 DSSDSSNSSDSSDSS----DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS- 885
Query: 129 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 188
N ++ D S ++D DS SN + + S +S
Sbjct: 886 -NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-SNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 189 TTDEEDSV-----LNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS 243
++D DS N + + S++ SS + ++ + S S +++ D S
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 244 GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIAR 303
S + + S + + S+ + + S + S + +SD +S +
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 304 GKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKA----T 359
SS + +++ S S+ + + D S S + + +
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 360 SDEEDSVLSIAREEKDGEKSRTVSSE 385
SD DS S + + SSE
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 42.7 bits (99), Expect = 6e-04
Identities = 61/374 (16%), Positives = 122/374 (32%), Gaps = 23/374 (6%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
S SS ++ + S D SN + + S +S +SD DS ++ +
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
+ + S S+ S + S S +SD +D
Sbjct: 958 NSSDSSNSSDSSDSNSS------------------DSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S+ + + + SS + ++ + S S+ +++ D S S +
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV-SIIATEIKDGEKSGT 245
+ + + + + + SE+ S ++D DS S +++ D S
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119
Query: 246 VSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGK 305
S+ + + S + SN + E S + S + +SD DS +
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS----SDSS 1175
Query: 306 EDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDS 365
+ + S +SD DS + + + SS + ++ E S
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Query: 366 VLSIAREEKDGEKS 379
S + + D S
Sbjct: 1236 DSSDSSDSSDSSNS 1249
Score = 41.2 bits (95), Expect = 0.002
Identities = 54/342 (15%), Positives = 121/342 (35%), Gaps = 3/342 (0%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S ++ + S D + S+ + S + S + +++ S S+ +++
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995
Query: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
+ S S S+ N + S + S S +SD +DS+
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055
Query: 129 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 188
+ + + SS + ++ + S S+ +++ D S S + +
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115
Query: 189 TTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV-SIIATEIKDGEKSGTVS 247
+ + + + + + S++ +S ++D DS S +++ D S S
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
+ + S + S+ + + S + S + +SD DS + + E
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSNES 1234
Query: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVS 349
+ + S +SD DS S+ T + D S++ S
Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDSSDS-SDSTSDSNDESDSQSKS 1275
Score = 40.8 bits (94), Expect = 0.002
Identities = 62/385 (16%), Positives = 133/385 (34%), Gaps = 8/385 (2%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV-SNIATEI 67
S ++ + SD DS + + + S + S +SD DS S+ +++
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
+ S S S+ + + S + S S +SD +DS
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKA-TTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
+ +++ + S+ + + ++D DS S+ ++ + S S +
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG-- 244
+ + + + N + S++ SS + ++ S S ++ D S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 245 ---TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSV-LN 300
+ SS + ++ S S+ + + D S + S + +SD DS +
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 301 IARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATS 360
+ D + S + + S + + S+ + ++S + S +S
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 361 DEEDSVLSIAREEKDGEKSRTVSSE 385
D DS S + + SSE
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSE 1083
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/373 (15%), Positives = 122/373 (32%), Gaps = 11/373 (2%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S ++ + S D + SN + S + SS + ++ S S+ ++
Sbjct: 871 SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930
Query: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKAT--SDKTD 126
+ S S S+ N + S + SS +S ++ SD +D
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S ++ D S + + + SN + + S + S
Sbjct: 991 S-----SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
++D DS + + + SS + ++ + S S +++ D S
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
S + + S + + S+ + + S + S + +SD DS + +
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS----SDSSD 1161
Query: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
+ + S +SD DS + + + SS + ++ + S
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221
Query: 367 LSIAREEKDGEKS 379
S + + D +S
Sbjct: 1222 SSDSSDSSDSNES 1234
Score = 40.0 bits (92), Expect = 0.004
Identities = 62/374 (16%), Positives = 132/374 (35%), Gaps = 30/374 (8%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S+ ++ + S D DS SN + S + +S +SD DS S+ ++
Sbjct: 804 SNSSDSSDSSDSSDSDS-SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862
Query: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
S S S S + S S +SD +DS+
Sbjct: 863 NSSDSSDSSDSSNS------------------------SDSSDSSDSNESSNSSDSSDSS 898
Query: 129 LNIATEIKDGLQC--GTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
+ ++ D + SS + +++ ++S S+ ++ D S S+ +
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 187 KA-TTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGT 245
+ +++ DS + +++ D S SS + ++ + S S +++ D S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSD-SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017
Query: 246 VSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGK 305
S + + S + S+ + + S + S + +SD DS + +
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS-SDSSDSS 1076
Query: 306 EDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDS 365
+ + + S +SD DS + + + SS + ++ + S
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 366 VLSIAREEKDGEKS 379
S + + D +S
Sbjct: 1137 DSSNSSDSSDSSES 1150
Score = 40.0 bits (92), Expect = 0.004
Identities = 57/374 (15%), Positives = 127/374 (33%), Gaps = 14/374 (3%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
S SS + ++ S S+ +++ E S S ++ +SD +S + +
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
+ S ++ S + ++ + S S+ + +SD +D
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978
Query: 127 SA-LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPA 185
S+ + +++ D S + + + + SN + + S + S
Sbjct: 979 SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Query: 186 LKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGT 245
++D DS + S++ +S ++D DS +++ D +S
Sbjct: 1039 SSDSSDSSDS----------SDSSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSESSD 1086
Query: 246 VSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGK 305
S + + S + S+ + + S + S + +SD DS N +
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS-SNSSDSS 1145
Query: 306 EDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDS 365
+ E + S +SD DS + + + SS + ++ + S
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1205
Query: 366 VLSIAREEKDGEKS 379
S + + D S
Sbjct: 1206 DSSDSSDSSDSSDS 1219
Score = 37.4 bits (85), Expect = 0.024
Identities = 56/357 (15%), Positives = 121/357 (33%), Gaps = 6/357 (1%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S ++ + S D + S+ + + SS + ++ S S+ +++
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
+ S S S+ + + S + S S +SD +DS+
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 129 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 188
+ + + SS + ++ + S S+ +++ D S S + +
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 189 TTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSS 248
+ + + + + SE+ S ++D DS +++ D S S
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD--SSDSSDSSNSSDSSD 1185
Query: 249 RKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG 308
+ + S + S+ + + S + S + +SD +S +
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Query: 309 EKTRRVSSRKKPALKATS---DEKDSFSNITREKKDGETSRTVSSQKPPALKATSDE 362
SS + +TS DE DS S +G S + S+ + +TSD+
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS-DSEGSDSNHSTSDD 1301
Score = 35.4 bits (80), Expect = 0.092
Identities = 47/218 (21%), Positives = 78/218 (35%), Gaps = 20/218 (9%)
Query: 168 EIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEE 227
E KD + +T+D +S N + + K + K +D
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN------GNGNNGNDDNDKSDSGKGKSDSS 550
Query: 228 DSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAG 287
DS S ++ D S S + + SD DS S+ + + + S + S +
Sbjct: 551 DSDSSDSSNSSDSSDSSDSDSSDSNS-SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD 609
Query: 288 LKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRT 347
+SD DS + K D K+ SS + SD DS S+ + + D S
Sbjct: 610 SSDSSDSSDS----SDSKSDSSKSESDSSDS----DSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 348 VSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSE 385
S+ +SD DS S + + + SS+
Sbjct: 662 SSNSSD-----SSDSSDSSDSSSSSDSSNSSDSSDSSD 694
>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
Length = 1341
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/292 (22%), Positives = 121/292 (41%), Gaps = 50/292 (17%)
Query: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
K V+S + S+ +K + + L+ SS+ + +DEEDS
Sbjct: 492 KEKAVASPEATVSQTDENKARAEKKVTLSSSKNLK---PSSETKTQKGLFSDEEDSEDLF 548
Query: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
+++ K ++ K P L + D+ED +D T + ++ L+A +
Sbjct: 549 SSQSASKLKGASLLPGKLPTLVSLFDDEDE--------EDNLFGGTAAKKQTLCLQAQRE 600
Query: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSF---------SNITREKKDGEI 276
E+ K+ +S +K AL +SDE+D + ++ +R K +
Sbjct: 601 EK-------------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRD 647
Query: 277 SRTVTSEKPAGLKATS----DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS- 331
S T+ S++ +K TS DEED + IA K+ +KT+RVS D+ DS
Sbjct: 648 SGTLQSQEAKAVKKTSLFEEDEEDDLFAIA--KDSQKKTQRVS-------LLFEDDVDSG 698
Query: 332 ---FSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSR 380
F + + S+ PP L + +E+++ L + +K E ++
Sbjct: 699 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 750
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 53.5 bits (127), Expect = 3e-07
Identities = 95/436 (21%), Positives = 167/436 (38%), Gaps = 61/436 (13%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
+ + + + + +SDD D +++G + + K P +KA S + DS S+ E
Sbjct: 120 AAKASESSSSEESSDDDDEEDQKKQPVQKG-VKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
+ Q+ ++ K K + IA GK+ + SS +S ++SD ++
Sbjct: 179 PPKNQKPKITPVTVKAQTKAPPKPARAAPKIAN-----GKAASSSSSS--SSSSSSDDSE 231
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATT------DEEDSVSNIATEIKDGEKS--GTV 178
AT K + V+ K P ATT EDS S+ E K K+ G
Sbjct: 232 EEKAAATPKKTVPKKQVVA--KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY 289
Query: 179 SS----------------------QKQPALKATTDEEDSVLNIATEIKDGEKSETVS--- 213
SS +KQ ++++ D D + + E K VS
Sbjct: 290 SSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 214 SQKQPALKA---TTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITRE 270
++ PA KA ++D DS S E T +S KPA+ S + +
Sbjct: 350 TKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQP 409
Query: 271 KKDGE--ISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDE 328
G+ ++R S ++S+EE + +A K +S K A + + D
Sbjct: 410 VGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDS 469
Query: 329 KDSFSNITREKKDGETSRTVSSQKP-------------PALKATSDEEDSVLSIAREEKD 375
+ + E+++ +TS++ +KP A K ++ +S S E++
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEE 529
Query: 376 GEKSRTVSSEQPPGLK 391
EK + S +P K
Sbjct: 530 EEKLKGKGSPRPQAPK 545
Score = 50.1 bits (118), Expect = 4e-06
Identities = 77/375 (20%), Positives = 147/375 (39%), Gaps = 36/375 (9%)
Query: 4 FCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 63
F + + +Q A ++ D S + ++ E + K+ +KA+S + + S
Sbjct: 34 FAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEE 93
Query: 64 ATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSD 123
E++ P K++A + K+V L GK+ +S+ +S+ +SD
Sbjct: 94 EEEVQG-------PPAKKAA---VPAKRVGL--------PPGKAAAKASESS-SSEESSD 134
Query: 124 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 183
D ++ G++ + K P KA + + DS S+ E +K
Sbjct: 135 DDDEEDQKKQPVQKGVK-PQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPV--- 190
Query: 184 PALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS 243
+KA T A +I +G+ + + SS +++D+ + AT K K
Sbjct: 191 -TVKAQTKAPPKPARAAPKIANGKAASSSSSSSS---SSSSDDSEEEKAAATPKKTVPKK 246
Query: 244 GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIAR 303
V+ K P AT+ + S S+ + E + KP + +
Sbjct: 247 QVVA--KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 304 GKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVS---SQKPPALKATS 360
G + +K + K+ ++++ D D + + E+K T VS ++ PPA KA
Sbjct: 305 GTQPPKK----AVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAE 360
Query: 361 DEEDSVLSIAREEKD 375
DS S + E+ +
Sbjct: 361 SSSDSSDSDSSEDDE 375
>gi|194473700 Src homology 3 domain-containing guanine nucleotide
exchange factor [Homo sapiens]
Length = 871
Score = 53.1 bits (126), Expect = 4e-07
Identities = 89/375 (23%), Positives = 142/375 (37%), Gaps = 61/375 (16%)
Query: 40 GTVSSQKQPAEKATSDEKDSVSN----IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLL 95
GT+ + + PA+ T+ + +V + + + GT SP+ ++A + + K L
Sbjct: 57 GTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKL 116
Query: 96 NIATRITGGGKSGTVSSQKQPASKATS------------DKTDSALNIATEIKD--GLQC 141
A + GG S K PA+ A + +T +A T +D GL
Sbjct: 117 PKA--VPGG-------SPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTA 167
Query: 142 GTVSSQKQPALKATTDEEDSVSNIATEIKDGEKS------GTVSSQKQPALKATTDEEDS 195
V S L A D S S + KD E+ + S QK P + + E +
Sbjct: 168 SPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENEL 227
Query: 196 VLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALK 255
+ E V S PA ++ +A+EIK + + K LK
Sbjct: 228 L----------ENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLK 277
Query: 256 ATSDEKDSFSNITREKKDGEISRTVTSEKPA--GLKATSDEEDSVLNIARGKEDGEKTRR 313
S + + ++ E+ V S GL++TS V K +
Sbjct: 278 VRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKN 337
Query: 314 VSSRKKPALKATSDEKDSFSNITREKK---------DGETSRTV-SSQKPPALKATSDEE 363
S+ P LK ++K+ FS++ R KK DGE + + + K AL SDEE
Sbjct: 338 RMSQ--PVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEE 395
Query: 364 DSVLSIAREEKDGEK 378
S +E+K EK
Sbjct: 396 ----SEPKEQKSDEK 406
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 52.4 bits (124), Expect = 7e-07
Identities = 99/425 (23%), Positives = 162/425 (38%), Gaps = 55/425 (12%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
S K+ +EK T K IA E KE +S K+ +EK T K IA E K
Sbjct: 307 SPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKK 366
Query: 69 EGQ-QSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPA-SKATSDKT- 125
E ++G V+ + KV+ K + ++ T+ + + + Q+ P+ SK D+
Sbjct: 367 ETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESS--TKASANDQRFPSESKQEEDEEY 424
Query: 126 --------DSALNIATEIKDGLQCGTVS--------SQKQPALKATTDEEDSVSNIATEI 169
+S+ I I + + + +K A K + ++SV N A E+
Sbjct: 425 SCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFEL 484
Query: 170 KDGE--------------KSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSE---TV 212
K+ + K +S +L T ++D L AT K+ +K
Sbjct: 485 KNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEE 544
Query: 213 SSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
S K LKAT + S+ A E+KD + K A + ++ + S N E K
Sbjct: 545 SPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELK 604
Query: 273 DGEISRT--------------VTSEKPAGLKATSDEEDSVLNIARGKEDGEKTR---RVS 315
+ + R S L T ++D L A +++ +K S
Sbjct: 605 NEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGS 664
Query: 316 SRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKD 375
K LKA K S E D +T + +KP A + + + SV + A E K+
Sbjct: 665 PVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKN 724
Query: 376 GEKSR 380
+ R
Sbjct: 725 EQTLR 729
Score = 48.9 bits (115), Expect = 8e-06
Identities = 93/375 (24%), Positives = 142/375 (37%), Gaps = 47/375 (12%)
Query: 9 SSQKQPAEKATSDD-KDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
S + Q EKATS + S EI S K+ +EK T K IA E
Sbjct: 280 SDKIQCLEKATSGKFEQSAEETPREI--------TSPAKETSEKFTWPAKGRPRKIAWEK 331
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
KE +SP K+++ K + K G+ ++ +K+ T
Sbjct: 332 KEDTPREIMSPAKETSEKFTWAAK-------------GRPRKIAWEKKETPVKTGCVARV 378
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
N ++ G K+ + KA+ +++ S E +D E S S + + K
Sbjct: 379 TSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQE-EDEEYSCDSRSLFESSAK 437
Query: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQP-ALKATTDEEDSVSIIATEIKDGEKSGTV 246
+S+ EI E K+P A K + ++SV A E+K+ +
Sbjct: 438 IQVCIPESIYQKVMEIN----REVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQ----- 488
Query: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGL-KATSDEEDSVLNIARGK 305
+ R P S +KD N D E S+K L KAT +E +N GK
Sbjct: 489 TLRADPMFPPESKQKDYEEN----SWDSESLCETVSQKDVCLPKATHQKEIDKIN---GK 541
Query: 306 EDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDS 365
+ S K LKAT K S E KD +T + KP A + ++ + S
Sbjct: 542 LEE------SPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKS 595
Query: 366 VLSIAREEKDGEKSR 380
V + A E K+ + R
Sbjct: 596 VPNKALELKNEQTLR 610
Score = 43.9 bits (102), Expect = 3e-04
Identities = 89/377 (23%), Positives = 145/377 (38%), Gaps = 45/377 (11%)
Query: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
C +VS + KAT + + I +++E P K KAT K S+ A
Sbjct: 516 CETVSQKDVCLPKATHQKE--IDKINGKLEESP-------NKDGLLKATCGMKVSIPTKA 566
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
E+K+ Q P K SA++ + + S+ N A + + + + P+ D
Sbjct: 567 LELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKN--EQTLRADEILPSESKQKDY 624
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
+++ + + C TVS + KA +E N G+ G S K
Sbjct: 625 EENSWDTES------LCETVSQKDVCLPKAAHQKEIDKIN-------GKLEG--SPVKDG 669
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
LKA + S+ A E+ D + + +K A + + + SV A E+K+ +
Sbjct: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQ--- 726
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGL-KATSDEEDSVLNIAR 303
+ R L + S +KD D E S+K L KAT +E +N
Sbjct: 727 --TLRADEILPSESKQKD----YEESSWDSESLCETVSQKDVCLPKATHQKEIDKIN--- 777
Query: 304 GKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEE 363
GK + S LKA K S E D +T + +KP A + + +
Sbjct: 778 GKLEE------SPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQ 831
Query: 364 DSVLSIAREEKDGEKSR 380
SV + A E K+ + R
Sbjct: 832 KSVPNKALELKNEQTLR 848
Score = 41.2 bits (95), Expect = 0.002
Identities = 93/375 (24%), Positives = 138/375 (36%), Gaps = 60/375 (16%)
Query: 26 VSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQ--QSGTVSP--QKQ 81
V I E++E P +K A K + ++SV N A E+K Q ++ + P KQ
Sbjct: 450 VMEINREVEEPP-------KKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQ 502
Query: 82 SAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQC 141
++ SL TVS + KAT K +N E
Sbjct: 503 KDYEENSWDSESLCE------------TVSQKDVCLPKATHQKEIDKINGKLE------- 543
Query: 142 GTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIAT 201
S K LKAT + S+ A E+KD + K A + T+ + SV N A
Sbjct: 544 --ESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKAL 601
Query: 202 EIKD--------------GEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK-SGTV 246
E+K+ +K +S +L T ++D A K+ +K +G +
Sbjct: 602 ELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKL 661
Query: 247 --SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
S K LKA K S E D + + EKP+ + + + SV N A
Sbjct: 662 EGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKAL- 720
Query: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPAL-KATSDEE 363
E + R L + S +KD D E+ SQK L KAT +E
Sbjct: 721 ----ELKNEQTLRADEILPSESKQKD----YEESSWDSESLCETVSQKDVCLPKATHQKE 772
Query: 364 -DSVLSIAREEKDGE 377
D + E D +
Sbjct: 773 IDKINGKLEESPDND 787
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 52.0 bits (123), Expect = 9e-07
Identities = 72/246 (29%), Positives = 93/246 (37%), Gaps = 46/246 (18%)
Query: 109 TVSSQKQPASKATSDKTDSALNIATE---IKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
TVS + KAT K L+ E +KDGL LK T + S+ N
Sbjct: 583 TVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL------------LKPTCGRKVSLPNK 630
Query: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
A E+KD E S K LK T + S+ N A E+KD E + S LK T
Sbjct: 631 ALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCG 690
Query: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEIS-------R 278
+ S+ A E+KD E T F + +++K D E S
Sbjct: 691 RKVSLPNKALELKDRE---------------TFKAAQMFPSESKQKDDEENSWDFESFLE 735
Query: 279 TVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITRE 338
T+ KAT +E L+ GK + S K LK T K S N E
Sbjct: 736 TLLQNDVCLPKATHQKEFDTLS---GKLE------ESPDKDGLLKPTCGMKISLPNKALE 786
Query: 339 KKDGET 344
KD ET
Sbjct: 787 LKDRET 792
Score = 48.5 bits (114), Expect = 1e-05
Identities = 102/414 (24%), Positives = 161/414 (38%), Gaps = 64/414 (15%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEK-DSVSNIATEI 67
++Q P+E DD+++ + E P TVS + KAT ++ D++S E
Sbjct: 557 AAQMFPSESKQKDDEENSWD-----SESPCE-TVSQKDVYLPKATHQKEFDTLSGKLEE- 609
Query: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
SP K K +KVSL N A + S K K T + S
Sbjct: 610 ---------SPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVS 660
Query: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGE-------------- 173
N A E+KD S LK T + S+ N A E+KD E
Sbjct: 661 LPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQ 720
Query: 174 KSGTVSSQKQPALKATTDEEDSVLNIATEIKD-----GEKSETVSSQKQPALKATTDEED 228
K +S + T + D L AT K+ G+ E S K LK T +
Sbjct: 721 KDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEE--SPDKDGLLKPTCGMKI 778
Query: 229 SVSIIATEIKDGE--KSGTVSSRKKPAL---KATSDEKDSFSNITREKKDGEISRTVTSE 283
S+ A E+KD E K+ VSS + K T++ S T+ ++D + T++
Sbjct: 779 SLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQS----TKVEEDFNL----TTK 830
Query: 284 KPAGLKATSDEEDSVLNIARGKEDGEKTRRVSS-RKKPALKATSDEK----------DSF 332
+ A T +E + I R +D S +K K+TSD + +
Sbjct: 831 EGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECL 890
Query: 333 SNITREKKDGETSRTV--SSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSS 384
T +K+ T+ + S +KP + ++ ++SV + E K+ + R S+
Sbjct: 891 PEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADST 944
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 51.6 bits (122), Expect = 1e-06
Identities = 83/339 (24%), Positives = 136/339 (40%), Gaps = 40/339 (11%)
Query: 46 KQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGG 105
++P K S N + I E Q G ++Q W SL+ I+ R
Sbjct: 41 QRPGTKRRSKPSQIRDNTVSIIDEEQLRGD---RRQPLWMYR-----SLMRISER----- 87
Query: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
S +++++QP + + DS A EI G + ++QK D DS S +
Sbjct: 88 PSVYLAARRQPLKPTRTVEVDSK---AAEI--GKKGEDKTTQK--------DTTDSESEL 134
Query: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT- 224
KD +K + K+ L A D + + + G+ S T S ++ K
Sbjct: 135 KQGKKDSKKGKDIEKGKEEKLDAKKDSKKG----KKDAEKGKDSATESEDEKGGAKKDNK 190
Query: 225 -DEEDSVS--IIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVT 281
D++DS ATE +GEK GT KK K + KDS + K D +
Sbjct: 191 KDKKDSNKGKDSATE-SEGEKGGTEKDSKK-GKKDSKKGKDSAIELQAVKADEKKDEDGK 248
Query: 282 SEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKD 341
+ G ++ ++D+ I +GK+D +K S K +K S +KD+ + + K
Sbjct: 249 KDANKGDESKDAKKDAK-EIKKGKKDKKKPSSTDSDSKDDVKKES-KKDATKDAKKVAKK 306
Query: 342 GETSRTVSSQKPPALKATSDEEDSVLSIAR--EEKDGEK 378
+ S+K A D + A+ E+KD +K
Sbjct: 307 DTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKK 345
Score = 32.0 bits (71), Expect = 1.0
Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 21/173 (12%)
Query: 221 KATTDEEDSVSIIATEIKDGEKSGT---------VSSRKKPALKATSDEKDSFSNITREK 271
K + +++VSII E G++ +S R L A + +
Sbjct: 50 KPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDS 109
Query: 272 KDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS 331
K EI + E K T+D E + +GK+D +K + + K+ L A D K
Sbjct: 110 KAAEIGKK--GEDKTTQKDTTDSESE---LKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
Query: 332 FSNITREKKDGETSRTVSSQKPPALKATS--DEEDSVL-SIAREEKDGEKSRT 381
++ + G+ S T S + K + D++DS + E +GEK T
Sbjct: 165 ----KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGT 213
Score = 32.0 bits (71), Expect = 1.0
Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSD-EKDSVSNIATE 66
+ K+ +K +S D DS ++ E K+ K+ EK ++D +KD+ N +
Sbjct: 267 IKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKD 326
Query: 67 IKEGQQSGTVSPQKQSAWK 85
K+ + +K+ A K
Sbjct: 327 AKKDAKKNAKKDEKKDAKK 345
>gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
Length = 1253
Score = 51.6 bits (122), Expect = 1e-06
Identities = 65/292 (22%), Positives = 120/292 (41%), Gaps = 50/292 (17%)
Query: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
K V+S + S+ +K + + L+ SS+ + +DEEDS
Sbjct: 404 KEKAVASPEATVSQTDENKARAEKKVTLSSSKNLK---PSSETKTQKGLFSDEEDSEDLF 460
Query: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
+++ K ++ K P + D+ED +D T + ++ L+A +
Sbjct: 461 SSQSASKLKGASLLPGKLPTSVSLFDDEDE--------EDNLFGGTAAKKQTLCLQAQRE 512
Query: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSF---------SNITREKKDGEI 276
E+ K+ +S +K AL +SDE+D + ++ +R K +
Sbjct: 513 EK-------------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRD 559
Query: 277 SRTVTSEKPAGLKATS----DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS- 331
S T+ S++ +K TS DEED + IA K+ +KT+RVS D+ DS
Sbjct: 560 SGTLQSQEAKAVKKTSLFEEDEEDDLFAIA--KDSQKKTQRVS-------LLFEDDVDSR 610
Query: 332 ---FSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSR 380
F + + S+ PP L + +E+++ L + +K E ++
Sbjct: 611 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 662
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 50.8 bits (120), Expect = 2e-06
Identities = 89/397 (22%), Positives = 146/397 (36%), Gaps = 43/397 (10%)
Query: 13 QPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQ 72
QP +K + + + A E T S +P EK SDEK + S +++
Sbjct: 3 QPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYA 62
Query: 73 SGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKT--DSALN 130
GT S K SA K S+ T+ V ++ + S++T K+ A +
Sbjct: 63 GGTASATKVSASSGATSKSSSMNPTETK--------AVKTEPEKKSQSTKPKSLPKQASD 114
Query: 131 IATEIKDGLQCGTVSSQKQPALKAT---TDEEDSVS----NIATEIKDGEKSGTVSSQKQ 183
+ + + S+++QP+ K+T T +D +S ++A K G +K+
Sbjct: 115 TGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKK 174
Query: 184 PALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS 243
A E D + + + P EE++ + E+ D S
Sbjct: 175 SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGP----EETEEENTTYTGPEVSDPMSS 230
Query: 244 GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIAR 303
+ K + ++ + KK+G S KP G D S
Sbjct: 231 TYIEELGKREVTIPPKYRELLA-----KKEGITGPPADSSKPIGPDDAIDALSSDFTCGS 285
Query: 304 GKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKAT---- 359
G+KT + S + LKA S + +EKK T+S Q AL A+
Sbjct: 286 PTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTR 343
Query: 360 -SDEEDSVLSI-------ARE---EKDGEKSRTVSSE 385
++ E + SI A+E EK GE T+ SE
Sbjct: 344 QAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSE 380
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 50.8 bits (120), Expect = 2e-06
Identities = 87/372 (23%), Positives = 133/372 (35%), Gaps = 39/372 (10%)
Query: 16 EKATSDDKDSVS-NIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE---IKEGQ 71
E AT+ ++ S S N + + S +S S S S++ + I
Sbjct: 19 EAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNS 78
Query: 72 QSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNI 131
+ T S +A F S ++IAT +S T SS A+ + S S +
Sbjct: 79 EFHTTSSGISTATNSEFSTVSSGISIATN----SESSTTSSGASTATNSESSTPSSGAST 134
Query: 132 ATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTD 191
AT S+ A AT + + S+ A+ + E S T S A AT
Sbjct: 135 ATNSDS-------STTSSGASTATNSDSSTTSSEASTATNSESSTTSSG----ASTATNS 183
Query: 192 EEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKK 251
E +V + A+ + E S T S A AT E + S A + E S T S
Sbjct: 184 ESSTVSSRASTATNSESSTTSSG----ASTATNSESRTTSNGAGTATNSESSTTSSG--- 236
Query: 252 PALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKT 311
A AT+ E T G + + +S +G ++ E S ++ ++
Sbjct: 237 -ASTATNSESS-----TPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSES 290
Query: 312 RRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAR 371
SS A + S S +N TS S+ AT+ E + S A
Sbjct: 291 STPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST-------ATNSESSTTSSGAS 343
Query: 372 EEKDGEKSRTVS 383
+ E S T S
Sbjct: 344 TATNSESSTTSS 355
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 50.1 bits (118), Expect = 4e-06
Identities = 75/336 (22%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGT 75
E A +D V + + G ++ ++ A KAT S S +T + G
Sbjct: 1109 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1168
Query: 76 VSPQKQSAWKVIFKKKVSLLNIATRITGGGK--SGTVSSQKQPASKATSDKTDSALNIAT 133
+ Q A ++ K TGG + SGT + + K + S L + +
Sbjct: 1169 QEAKPQQAAGMLSPK-----------TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1217
Query: 134 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 193
I QC + Q P +A + SV + TE+ + E+ V + K+ + K +
Sbjct: 1218 NIT---QC--LLGQPWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1270
Query: 194 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 253
+ D + T S+K+ L A E SVS EK+ T S K
Sbjct: 1271 RKLSG------DQPAARTPRSKKKKKLGAGEGGEASVS--------PEKTSTTSKGKAKR 1316
Query: 254 LKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG-EKTR 312
KA+ D K+ + + + +K G D+ + + K D +K +
Sbjct: 1317 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1376
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTV 348
+KK A KA++ + +S S ++KK +TV
Sbjct: 1377 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
Score = 46.2 bits (108), Expect = 5e-05
Identities = 86/419 (20%), Positives = 158/419 (37%), Gaps = 50/419 (11%)
Query: 3 PFCFSVSSQKQPAEKATSDDKD------SVSNIATEIKEGPISGTVSSQKQPAEKATSDE 56
P V ++KQ +++ ++ D S + + T +K+ ++ + P+ K T
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 731
Query: 57 KDSVSNIATEIKEGQQSGTVSP-QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQ 115
V A + K+ S P + V+ + S+ ++ + ++ T +
Sbjct: 732 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 791
Query: 116 PASKATSDKTDSALNIAT--------EIKDGLQCGTVSSQK----------QPALKATTD 157
+S+ SD + A +A +I+ L S +K P+
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 851
Query: 158 EEDSVSNIATEIKDGEKSGTVSSQK--QPALKATTDEEDSVLNIAT--EIKDGEKSETVS 213
++DS S+ DGE V+S + +P L AT + +
Sbjct: 852 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 911
Query: 214 SQKQPALKATTDEEDSVSIIATE-IKDGEKSGTVSS-------RKKPALKATSDEKDSFS 265
+ + A ++++ ED I AT+ + G ++ V+ K ++ S K+S S
Sbjct: 912 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES-S 970
Query: 266 NITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPA---L 322
I+ KK + V+ + PA L T + A + + SS A L
Sbjct: 971 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1030
Query: 323 KATSDEKDSF----SNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGE 377
ATS + S +N R+ K E Q A +++ D EDS S + E+DGE
Sbjct: 1031 PATSPQSTSVQAKGTNKLRKPKLPEV-----QQATKAPESSDDSEDSSDSSSGSEEDGE 1084
Score = 44.7 bits (104), Expect = 2e-04
Identities = 77/366 (21%), Positives = 135/366 (36%), Gaps = 46/366 (12%)
Query: 12 KQPAEKATSDDKDSVSNIATEIKEGP--------ISGTVSSQKQPA--EKATSDEKDSVS 61
K P S+D S+ + E EGP + G S+ + E A +D V
Sbjct: 1061 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1120
Query: 62 NIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKAT 121
+ + G + ++P A K K S +T G ++ Q A+
Sbjct: 1121 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1180
Query: 122 SDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQ 181
S KT K+ GT + + K + + S + + I + Q
Sbjct: 1181 SPKTGG--------KEAAS-GTTPQKSRKPKKGAGNPQASTLALQSNITQ-----CLLGQ 1226
Query: 182 KQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGE 241
P +A + SV+ + TE+ + E+ + V + K+ + K + +S D
Sbjct: 1227 PWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS------GDQP 1278
Query: 242 KSGTVSSRKKPALKA-------TSDEKDSFSNITREKKD---GEISRTVTSEKPAGLKAT 291
+ T S+KK L A S EK S ++ + K+D G++ + + G +
Sbjct: 1279 AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGA 1337
Query: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
DE + L G +G S+K+ K SD++ +KK + + T S+
Sbjct: 1338 KDEPEEELQKGMGTVEGGDQSNPKSKKE---KKKSDKRKKDKEKKEKKKKAKKASTKDSE 1394
Query: 352 KPPALK 357
P K
Sbjct: 1395 SPSQKK 1400
Score = 44.3 bits (103), Expect = 2e-04
Identities = 76/381 (19%), Positives = 137/381 (35%), Gaps = 46/381 (12%)
Query: 34 KEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQ-KQSAWKVIFKK-- 90
K GP++ V ++K P + + S E+ S S + E + P K K KK
Sbjct: 514 KAGPVAVQVKAEK-PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 572
Query: 91 -----KVSLLNIATRITGGGKSGTVSSQKQPA-----SKATSDKTDSALNIATEIKDGLQ 140
KV+ + + T+ + T + PA + D + S + + E K GL
Sbjct: 573 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 632
Query: 141 CGTVSSQKQ-----PALKATTDEEDSVSNIATEIKDGEKSGTVS---SQKQPALKATTDE 192
TV K A+ + S+ + G+ TV+ ++KQ +++ +E
Sbjct: 633 V-TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 691
Query: 193 EDSV------LNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
DS + T +K + ++ + P+ K T V A + K S
Sbjct: 692 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 751
Query: 247 SSRKKPALKAT-SDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGK 305
+ P + S ++ + ++T E + SD E+ +A+ K
Sbjct: 752 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 811
Query: 306 EDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDS 365
G KT ++ + PA +E + T + P+ ++DS
Sbjct: 812 PSG-KTHQIRAALAPA---------------KESPRKGAAPTPPGKTGPSAAQAGKQDDS 855
Query: 366 VLSIAREEKDGEKSRTVSSEQ 386
S + DGE V+S Q
Sbjct: 856 GSSSEESDSDGEAPAAVTSAQ 876
Score = 40.8 bits (94), Expect = 0.002
Identities = 72/345 (20%), Positives = 126/345 (36%), Gaps = 36/345 (10%)
Query: 34 KEGPISGTVSSQKQPAEKATSDEKD------SVSNIATEIKEGQQSGTVSPQKQSAWKVI 87
K GP V ++KQ +++ +E D S + + T +K+ Q + + + K
Sbjct: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK-- 726
Query: 88 FKKKVSLLNIATRITGGGKSGTVSSQ-KQPASKATSDKTDSALNIATEIKDGLQCGTVSS 146
I+ GK T ++Q KQ + + N + +V
Sbjct: 727 -----------GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 775
Query: 147 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 206
A +A T E+ S + E D E+ +Q +P+ K T + + L A E
Sbjct: 776 AVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK--THQIRAALAPAKESPRK 832
Query: 207 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRK--KPALKATSDEKDSF 264
+ T + P+ ++DS S DGE V+S + KP L +
Sbjct: 833 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 892
Query: 265 SNITREKKDGEIS---RTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSS----- 316
+ S + SE A ++ E++ V+ + G +T V+
Sbjct: 893 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP 952
Query: 317 --RKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKAT 359
K ++ S K+S S I+ KK + VS + P +L T
Sbjct: 953 RIAPKASMAGASSSKES-SRISDGKKQEGPATQVSKKNPASLPLT 996
Score = 33.5 bits (75), Expect = 0.35
Identities = 60/323 (18%), Positives = 115/323 (35%), Gaps = 32/323 (9%)
Query: 79 QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPAS-KATSDKTDSALNIATEIKD 137
++QS K + V+LL+I T + G ++ A+ +A + ++ + ++
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE 90
Query: 138 GLQCGTVSSQKQPALKATTDE---EDSVSNIATEIK-DGEKSG-TVSSQKQPALKATTDE 192
+ +++ P L +T D S++ + K + EK+G T +S PA T
Sbjct: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT--- 147
Query: 193 EDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKP 252
+A + ++ L + T+EE SV K G S +
Sbjct: 148 ------VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 253 ALKATSDEKDSFSNITRE---------KKDGEISRTVTSEKP-------AGLKATSDEED 296
++SDE D + + G + T P + KA EED
Sbjct: 202 DTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 261
Query: 297 SVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREK-KDGETSRTVSSQKPPA 355
S + + E+T + + + + + S +E + G P
Sbjct: 262 SESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 321
Query: 356 LKATSDEEDSVLSIAREEKDGEK 378
KA + + + + EE D E+
Sbjct: 322 AKAQAGKREEDSQSSSEESDSEE 344
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 50.1 bits (118), Expect = 4e-06
Identities = 75/336 (22%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGT 75
E A +D V + + G ++ ++ A KAT S S +T + G
Sbjct: 1148 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1207
Query: 76 VSPQKQSAWKVIFKKKVSLLNIATRITGGGK--SGTVSSQKQPASKATSDKTDSALNIAT 133
+ Q A ++ K TGG + SGT + + K + S L + +
Sbjct: 1208 QEAKPQQAAGMLSPK-----------TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1256
Query: 134 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 193
I QC + Q P +A + SV + TE+ + E+ V + K+ + K +
Sbjct: 1257 NIT---QC--LLGQPWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1309
Query: 194 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 253
+ D + T S+K+ L A E SVS EK+ T S K
Sbjct: 1310 RKLSG------DQPAARTPRSKKKKKLGAGEGGEASVS--------PEKTSTTSKGKAKR 1355
Query: 254 LKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG-EKTR 312
KA+ D K+ + + + +K G D+ + + K D +K +
Sbjct: 1356 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1415
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTV 348
+KK A KA++ + +S S ++KK +TV
Sbjct: 1416 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
Score = 47.4 bits (111), Expect = 2e-05
Identities = 85/430 (19%), Positives = 155/430 (36%), Gaps = 46/430 (10%)
Query: 3 PFCFSVSSQKQPAEKATSDDKD------SVSNIATEIKEGPISGTVSSQKQPAEKATSDE 56
P V ++KQ +++ ++ D S + + T +K+ ++ + P+ K T
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 57 KDSVSNIATEIKEGQQSGTVSP-QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQ 115
V A + K+ S P + V+ + S+ ++ + ++ T +
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 116 PASKATSDKTDSALNIAT--------EIKDGLQCGTVSSQK----------QPALKATTD 157
+S+ SD + A +A +I+ L S +K P+
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 158 EEDSVSNIATEIKDGEKSGTVSSQK--QPALKATTDEEDSVLNIAT--EIKDGEKSETVS 213
++DS S+ DGE V+S + +P L AT + +
Sbjct: 929 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 988
Query: 214 SQKQPALKATTDEEDSVSIIATE-IKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
+ + A ++++ ED I AT+ + G ++ V+ P K S + + K+
Sbjct: 989 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT---MPTAHPRIAPKASMAGASSSKE 1045
Query: 273 DGEISRTVTSEKPA--------GLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKA 324
IS E PA L ATS + SV K K V K A ++
Sbjct: 1046 SSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK-APES 1104
Query: 325 TSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGE----KSR 380
+ D +DS + + ++DGE + S S E V A E + +
Sbjct: 1105 SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQS 1164
Query: 381 TVSSEQPPGL 390
+S PGL
Sbjct: 1165 LLSGYMTPGL 1174
Score = 44.7 bits (104), Expect = 2e-04
Identities = 77/366 (21%), Positives = 135/366 (36%), Gaps = 46/366 (12%)
Query: 12 KQPAEKATSDDKDSVSNIATEIKEGP--------ISGTVSSQKQPA--EKATSDEKDSVS 61
K P S+D S+ + E EGP + G S+ + E A +D V
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
Query: 62 NIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKAT 121
+ + G + ++P A K K S +T G ++ Q A+
Sbjct: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1219
Query: 122 SDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQ 181
S KT K+ GT + + K + + S + + I + Q
Sbjct: 1220 SPKTGG--------KEAAS-GTTPQKSRKPKKGAGNPQASTLALQSNITQ-----CLLGQ 1265
Query: 182 KQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGE 241
P +A + SV+ + TE+ + E+ + V + K+ + K + +S D
Sbjct: 1266 PWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS------GDQP 1317
Query: 242 KSGTVSSRKKPALKA-------TSDEKDSFSNITREKKD---GEISRTVTSEKPAGLKAT 291
+ T S+KK L A S EK S ++ + K+D G++ + + G +
Sbjct: 1318 AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGA 1376
Query: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
DE + L G +G S+K+ K SD++ +KK + + T S+
Sbjct: 1377 KDEPEEELQKGMGTVEGGDQSNPKSKKE---KKKSDKRKKDKEKKEKKKKAKKASTKDSE 1433
Query: 352 KPPALK 357
P K
Sbjct: 1434 SPSQKK 1439
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/321 (22%), Positives = 124/321 (38%), Gaps = 55/321 (17%)
Query: 79 QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIA-TEIKD 137
++QS K + V+LL+I T + G +K+ A + D+AL T + D
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELG----RKRKAEE------DAALQAKKTRVSD 80
Query: 138 GLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVL 197
+ S +++ A T +++ + + + SS K+ A KA T++
Sbjct: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLP---SSMKEKA-KAETEKAGKTG 136
Query: 198 NIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV---SSRKKPAL 254
N G+ + S K P A S T + + E+ G+V + KP +
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEP------SANTTLVSETEEEGSVPAFGAAAKPGM 190
Query: 255 KATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRV 314
++ + DS S T D S KPA +KA+S V
Sbjct: 191 -VSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS---------------------V 228
Query: 315 SSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEK 374
S+++ PA KA + ++T + K G PPA +A EE+S S E
Sbjct: 229 STKESPARKA-APAPGKVGDVTPQVKGGAL--------PPAKRAKKPEEESESSEEGSES 279
Query: 375 DGEKSRTVSSEQPPGLKVMKL 395
+ E S+ K++++
Sbjct: 280 EEEAPAGTRSQVKASEKILQV 300
Score = 38.5 bits (88), Expect = 0.011
Identities = 72/352 (20%), Positives = 129/352 (36%), Gaps = 37/352 (10%)
Query: 34 KEGPISGTVSSQKQPAEKATSDEKD------SVSNIATEIKEGQQSGTVSPQKQSAWKVI 87
K GP V ++KQ +++ +E D S + + T +K+ Q + + + K
Sbjct: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK-- 803
Query: 88 FKKKVSLLNIATRITGGGKSGTVSSQ-KQPASKATSDKTDSALNIATEIKDGLQCGTVSS 146
I+ GK T ++Q KQ + + N + +V
Sbjct: 804 -----------GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 147 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 206
A +A T E+ S + E D E+ +Q +P+ K T + + L A E
Sbjct: 853 AVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK--THQIRAALAPAKESPRK 909
Query: 207 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRK--KPALKATSDEKDSF 264
+ T + P+ ++DS S DGE V+S + KP L +
Sbjct: 910 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
Query: 265 SNITREKKDGEIS---RTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSS----- 316
+ S + SE A ++ E++ V+ + G +T V+
Sbjct: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP 1029
Query: 317 --RKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
K ++ S K+S +K++G ++ S+ L ATS + SV
Sbjct: 1030 RIAPKASMAGASSSKESSRISDGKKQEGPATQVDSA--VGTLPATSPQSTSV 1079
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 50.1 bits (118), Expect = 4e-06
Identities = 75/336 (22%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGT 75
E A +D V + + G ++ ++ A KAT S S +T + G
Sbjct: 1185 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1244
Query: 76 VSPQKQSAWKVIFKKKVSLLNIATRITGGGK--SGTVSSQKQPASKATSDKTDSALNIAT 133
+ Q A ++ K TGG + SGT + + K + S L + +
Sbjct: 1245 QEAKPQQAAGMLSPK-----------TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1293
Query: 134 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 193
I QC + Q P +A + SV + TE+ + E+ V + K+ + K +
Sbjct: 1294 NIT---QC--LLGQPWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1346
Query: 194 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 253
+ D + T S+K+ L A E SVS EK+ T S K
Sbjct: 1347 RKLSG------DQPAARTPRSKKKKKLGAGEGGEASVS--------PEKTSTTSKGKAKR 1392
Query: 254 LKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG-EKTR 312
KA+ D K+ + + + +K G D+ + + K D +K +
Sbjct: 1393 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1452
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTV 348
+KK A KA++ + +S S ++KK +TV
Sbjct: 1453 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
Score = 46.6 bits (109), Expect = 4e-05
Identities = 88/431 (20%), Positives = 161/431 (37%), Gaps = 50/431 (11%)
Query: 3 PFCFSVSSQKQPAEKATSDDKD------SVSNIATEIKEGPISGTVSSQKQPAEKATSDE 56
P V ++KQ +++ ++ D S + + T +K+ ++ + P+ K T
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 57 KDSVSNIATEIKEGQQSGTVSP-QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQ 115
V A + K+ S P + V+ + S+ ++ + ++ T +
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 116 PASKATSDKTDSALNIAT--------EIKDGLQCGTVSSQK----------QPALKATTD 157
+S+ SD + A +A +I+ L S +K P+
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 158 EEDSVSNIATEIKDGEKSGTVSSQK--QPALKATTDEEDSVLNIAT--EIKDGEKSETVS 213
++DS S+ DGE V+S + +P L AT + +
Sbjct: 929 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 988
Query: 214 SQKQPALKATTDEEDSVSIIATE-IKDGEKSGTVSS-------RKKPALKATSDEKDSFS 265
+ + A ++++ ED I AT+ + G ++ V+ K ++ S K+S S
Sbjct: 989 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES-S 1047
Query: 266 NITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPA---L 322
I+ KK + V+ + PA L T + A + + SS A L
Sbjct: 1048 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1107
Query: 323 KATSDEKDSF----SNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEK 378
ATS + S +N R+ K E Q A +++ D EDS S + E+DGE
Sbjct: 1108 PATSPQSTSVQAKGTNKLRKPKLPEV-----QQATKAPESSDDSEDSSDSSSGSEEDGEG 1162
Query: 379 SRTVSSEQPPG 389
+ S G
Sbjct: 1163 PQGAKSAHTLG 1173
Score = 44.7 bits (104), Expect = 2e-04
Identities = 76/365 (20%), Positives = 132/365 (36%), Gaps = 45/365 (12%)
Query: 12 KQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPA---------EKATSDEKDSVSN 62
K P S+D S+ + E EGP + P E A +D V
Sbjct: 1138 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVA 1197
Query: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
+ + G + ++P A K K S +T G ++ Q A+ S
Sbjct: 1198 PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1257
Query: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
KT K+ GT + + K + + S + + I + Q
Sbjct: 1258 PKTGG--------KEAAS-GTTPQKSRKPKKGAGNPQASTLALQSNITQ-----CLLGQP 1303
Query: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
P +A + SV+ + TE+ + E+ + V + K+ + K + +S D
Sbjct: 1304 WPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS------GDQPA 1355
Query: 243 SGTVSSRKKPALKA-------TSDEKDSFSNITREKKD---GEISRTVTSEKPAGLKATS 292
+ T S+KK L A S EK S ++ + K+D G++ + + G +
Sbjct: 1356 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGAK 1414
Query: 293 DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQK 352
DE + L G +G S+K+ K SD++ +KK + + T S+
Sbjct: 1415 DEPEEELQKGMGTVEGGDQSNPKSKKE---KKKSDKRKKDKEKKEKKKKAKKASTKDSES 1471
Query: 353 PPALK 357
P K
Sbjct: 1472 PSQKK 1476
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/321 (22%), Positives = 124/321 (38%), Gaps = 55/321 (17%)
Query: 79 QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIA-TEIKD 137
++QS K + V+LL+I T + G +K+ A + D+AL T + D
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELG----RKRKAEE------DAALQAKKTRVSD 80
Query: 138 GLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVL 197
+ S +++ A T +++ + + + SS K+ A KA T++
Sbjct: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLP---SSMKEKA-KAETEKAGKTG 136
Query: 198 NIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV---SSRKKPAL 254
N G+ + S K P A S T + + E+ G+V + KP +
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEP------SANTTLVSETEEEGSVPAFGAAAKPGM 190
Query: 255 KATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRV 314
++ + DS S T D S KPA +KA+S V
Sbjct: 191 -VSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS---------------------V 228
Query: 315 SSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEK 374
S+++ PA KA + ++T + K G PPA +A EE+S S E
Sbjct: 229 STKESPARKA-APAPGKVGDVTPQVKGGAL--------PPAKRAKKPEEESESSEEGSES 279
Query: 375 DGEKSRTVSSEQPPGLKVMKL 395
+ E S+ K++++
Sbjct: 280 EEEAPAGTRSQVKASEKILQV 300
Score = 40.8 bits (94), Expect = 0.002
Identities = 72/345 (20%), Positives = 126/345 (36%), Gaps = 36/345 (10%)
Query: 34 KEGPISGTVSSQKQPAEKATSDEKD------SVSNIATEIKEGQQSGTVSPQKQSAWKVI 87
K GP V ++KQ +++ +E D S + + T +K+ Q + + + K
Sbjct: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK-- 803
Query: 88 FKKKVSLLNIATRITGGGKSGTVSSQ-KQPASKATSDKTDSALNIATEIKDGLQCGTVSS 146
I+ GK T ++Q KQ + + N + +V
Sbjct: 804 -----------GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 147 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 206
A +A T E+ S + E D E+ +Q +P+ K T + + L A E
Sbjct: 853 AVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK--THQIRAALAPAKESPRK 909
Query: 207 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRK--KPALKATSDEKDSF 264
+ T + P+ ++DS S DGE V+S + KP L +
Sbjct: 910 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
Query: 265 SNITREKKDGEIS---RTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSS----- 316
+ S + SE A ++ E++ V+ + G +T V+
Sbjct: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP 1029
Query: 317 --RKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKAT 359
K ++ S K+S S I+ KK + VS + P +L T
Sbjct: 1030 RIAPKASMAGASSSKES-SRISDGKKQEGPATQVSKKNPASLPLT 1073
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 50.1 bits (118), Expect = 4e-06
Identities = 75/336 (22%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGT 75
E A +D V + + G ++ ++ A KAT S S +T + G
Sbjct: 1108 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1167
Query: 76 VSPQKQSAWKVIFKKKVSLLNIATRITGGGK--SGTVSSQKQPASKATSDKTDSALNIAT 133
+ Q A ++ K TGG + SGT + + K + S L + +
Sbjct: 1168 QEAKPQQAAGMLSPK-----------TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1216
Query: 134 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 193
I QC + Q P +A + SV + TE+ + E+ V + K+ + K +
Sbjct: 1217 NIT---QC--LLGQPWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1269
Query: 194 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 253
+ D + T S+K+ L A E SVS EK+ T S K
Sbjct: 1270 RKLSG------DQPAARTPRSKKKKKLGAGEGGEASVS--------PEKTSTTSKGKAKR 1315
Query: 254 LKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG-EKTR 312
KA+ D K+ + + + +K G D+ + + K D +K +
Sbjct: 1316 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1375
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTV 348
+KK A KA++ + +S S ++KK +TV
Sbjct: 1376 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1411
Score = 46.6 bits (109), Expect = 4e-05
Identities = 88/431 (20%), Positives = 161/431 (37%), Gaps = 50/431 (11%)
Query: 3 PFCFSVSSQKQPAEKATSDDKD------SVSNIATEIKEGPISGTVSSQKQPAEKATSDE 56
P V ++KQ +++ ++ D S + + T +K+ ++ + P+ K T
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 731
Query: 57 KDSVSNIATEIKEGQQSGTVSP-QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQ 115
V A + K+ S P + V+ + S+ ++ + ++ T +
Sbjct: 732 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 791
Query: 116 PASKATSDKTDSALNIAT--------EIKDGLQCGTVSSQK----------QPALKATTD 157
+S+ SD + A +A +I+ L S +K P+
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 851
Query: 158 EEDSVSNIATEIKDGEKSGTVSSQK--QPALKATTDEEDSVLNIAT--EIKDGEKSETVS 213
++DS S+ DGE V+S + +P L AT + +
Sbjct: 852 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 911
Query: 214 SQKQPALKATTDEEDSVSIIATE-IKDGEKSGTVSS-------RKKPALKATSDEKDSFS 265
+ + A ++++ ED I AT+ + G ++ V+ K ++ S K+S S
Sbjct: 912 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES-S 970
Query: 266 NITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPA---L 322
I+ KK + V+ + PA L T + A + + SS A L
Sbjct: 971 RISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTL 1030
Query: 323 KATSDEKDSF----SNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEK 378
ATS + S +N R+ K E Q A +++ D EDS S + E+DGE
Sbjct: 1031 PATSPQSTSVQAKGTNKLRKPKLPEV-----QQATKAPESSDDSEDSSDSSSGSEEDGEG 1085
Query: 379 SRTVSSEQPPG 389
+ S G
Sbjct: 1086 PQGAKSAHTLG 1096
Score = 44.7 bits (104), Expect = 2e-04
Identities = 76/365 (20%), Positives = 132/365 (36%), Gaps = 45/365 (12%)
Query: 12 KQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPA---------EKATSDEKDSVSN 62
K P S+D S+ + E EGP + P E A +D V
Sbjct: 1061 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVA 1120
Query: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
+ + G + ++P A K K S +T G ++ Q A+ S
Sbjct: 1121 PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1180
Query: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
KT K+ GT + + K + + S + + I + Q
Sbjct: 1181 PKTGG--------KEAAS-GTTPQKSRKPKKGAGNPQASTLALQSNITQ-----CLLGQP 1226
Query: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
P +A + SV+ + TE+ + E+ + V + K+ + K + +S D
Sbjct: 1227 WPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS------GDQPA 1278
Query: 243 SGTVSSRKKPALKA-------TSDEKDSFSNITREKKD---GEISRTVTSEKPAGLKATS 292
+ T S+KK L A S EK S ++ + K+D G++ + + G +
Sbjct: 1279 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGAK 1337
Query: 293 DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQK 352
DE + L G +G S+K+ K SD++ +KK + + T S+
Sbjct: 1338 DEPEEELQKGMGTVEGGDQSNPKSKKE---KKKSDKRKKDKEKKEKKKKAKKASTKDSES 1394
Query: 353 PPALK 357
P K
Sbjct: 1395 PSQKK 1399
Score = 40.8 bits (94), Expect = 0.002
Identities = 72/345 (20%), Positives = 126/345 (36%), Gaps = 36/345 (10%)
Query: 34 KEGPISGTVSSQKQPAEKATSDEKD------SVSNIATEIKEGQQSGTVSPQKQSAWKVI 87
K GP V ++KQ +++ +E D S + + T +K+ Q + + + K
Sbjct: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK-- 726
Query: 88 FKKKVSLLNIATRITGGGKSGTVSSQ-KQPASKATSDKTDSALNIATEIKDGLQCGTVSS 146
I+ GK T ++Q KQ + + N + +V
Sbjct: 727 -----------GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 775
Query: 147 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 206
A +A T E+ S + E D E+ +Q +P+ K T + + L A E
Sbjct: 776 AVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK--THQIRAALAPAKESPRK 832
Query: 207 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRK--KPALKATSDEKDSF 264
+ T + P+ ++DS S DGE V+S + KP L +
Sbjct: 833 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 892
Query: 265 SNITREKKDGEIS---RTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSS----- 316
+ S + SE A ++ E++ V+ + G +T V+
Sbjct: 893 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP 952
Query: 317 --RKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKAT 359
K ++ S K+S S I+ KK + VS + P +L T
Sbjct: 953 RIAPKASMAGASSSKES-SRISDGKKQEGPATQVSKKNPASLPLT 996
Score = 33.5 bits (75), Expect = 0.35
Identities = 60/323 (18%), Positives = 115/323 (35%), Gaps = 32/323 (9%)
Query: 79 QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPAS-KATSDKTDSALNIATEIKD 137
++QS K + V+LL+I T + G ++ A+ +A + ++ + ++
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE 90
Query: 138 GLQCGTVSSQKQPALKATTDE---EDSVSNIATEIK-DGEKSG-TVSSQKQPALKATTDE 192
+ +++ P L +T D S++ + K + EK+G T +S PA T
Sbjct: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT--- 147
Query: 193 EDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKP 252
+A + ++ L + T+EE SV K G S +
Sbjct: 148 ------VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 253 ALKATSDEKDSFSNITRE---------KKDGEISRTVTSEKP-------AGLKATSDEED 296
++SDE D + + G + T P + KA EED
Sbjct: 202 DTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 261
Query: 297 SVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREK-KDGETSRTVSSQKPPA 355
S + + E+T + + + + + S +E + G P
Sbjct: 262 SESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 321
Query: 356 LKATSDEEDSVLSIAREEKDGEK 378
KA + + + + EE D E+
Sbjct: 322 AKAQAGKREEDSQSSSEESDSEE 344
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 50.1 bits (118), Expect = 4e-06
Identities = 75/336 (22%), Positives = 128/336 (38%), Gaps = 35/336 (10%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGT 75
E A +D V + + G ++ ++ A KAT S S +T + G
Sbjct: 1147 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1206
Query: 76 VSPQKQSAWKVIFKKKVSLLNIATRITGGGK--SGTVSSQKQPASKATSDKTDSALNIAT 133
+ Q A ++ K TGG + SGT + + K + S L + +
Sbjct: 1207 QEAKPQQAAGMLSPK-----------TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1255
Query: 134 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 193
I QC + Q P +A + SV + TE+ + E+ V + K+ + K +
Sbjct: 1256 NIT---QC--LLGQPWPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1308
Query: 194 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 253
+ D + T S+K+ L A E SVS EK+ T S K
Sbjct: 1309 RKLSG------DQPAARTPRSKKKKKLGAGEGGEASVS--------PEKTSTTSKGKAKR 1354
Query: 254 LKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG-EKTR 312
KA+ D K+ + + + +K G D+ + + K D +K +
Sbjct: 1355 DKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK 1414
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTV 348
+KK A KA++ + +S S ++KK +TV
Sbjct: 1415 EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1450
Score = 47.4 bits (111), Expect = 2e-05
Identities = 81/429 (18%), Positives = 159/429 (37%), Gaps = 45/429 (10%)
Query: 3 PFCFSVSSQKQPAEKATSDDKD------SVSNIATEIKEGPISGTVSSQKQPAEKATSDE 56
P V ++KQ +++ ++ D S + + T +K+ ++ + P+ K T
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 57 KDSVSNIATEIKEGQQSGTVSP-QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQ 115
V A + K+ S P + V+ + S+ ++ + ++ T +
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 116 PASKATSDKTDSALNIAT--------EIKDGLQCGTVSSQK----------QPALKATTD 157
+S+ SD + A +A +I+ L S +K P+
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 158 EEDSVSNIATEIKDGEKSGTVSSQK--QPALKATTDEEDSVLNIAT--EIKDGEKSETVS 213
++DS S+ DGE V+S + +P L AT + +
Sbjct: 929 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 988
Query: 214 SQKQPALKATTDEEDSVSIIATE-IKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
+ + A ++++ ED I AT+ + G ++ V+ P K S + + K+
Sbjct: 989 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT---MPTAHPRIAPKASMAGASSSKE 1045
Query: 273 DGEISRTVTSEKPA--------GLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKA 324
IS E PA L ATS + SV K K V K A ++
Sbjct: 1046 SSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK-APES 1104
Query: 325 TSDEKDSFSNITREKKDGE---TSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRT 381
+ D +DS + + ++DGE +++ + P + + E++ + ++
Sbjct: 1105 SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSL 1164
Query: 382 VSSEQPPGL 390
+S PGL
Sbjct: 1165 LSGYMTPGL 1173
Score = 44.7 bits (104), Expect = 2e-04
Identities = 76/365 (20%), Positives = 132/365 (36%), Gaps = 45/365 (12%)
Query: 12 KQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPA---------EKATSDEKDSVSN 62
K P S+D S+ + E EGP + P E A +D V
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVA 1159
Query: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
+ + G + ++P A K K S +T G ++ Q A+ S
Sbjct: 1160 PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1219
Query: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
KT K+ GT + + K + + S + + I + Q
Sbjct: 1220 PKTGG--------KEAAS-GTTPQKSRKPKKGAGNPQASTLALQSNITQ-----CLLGQP 1265
Query: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
P +A + SV+ + TE+ + E+ + V + K+ + K + +S D
Sbjct: 1266 WPLNEAQV--QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS------GDQPA 1317
Query: 243 SGTVSSRKKPALKA-------TSDEKDSFSNITREKKD---GEISRTVTSEKPAGLKATS 292
+ T S+KK L A S EK S ++ + K+D G++ + + G +
Sbjct: 1318 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGAK 1376
Query: 293 DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQK 352
DE + L G +G S+K+ K SD++ +KK + + T S+
Sbjct: 1377 DEPEEELQKGMGTVEGGDQSNPKSKKE---KKKSDKRKKDKEKKEKKKKAKKASTKDSES 1433
Query: 353 PPALK 357
P K
Sbjct: 1434 PSQKK 1438
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/321 (22%), Positives = 124/321 (38%), Gaps = 55/321 (17%)
Query: 79 QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIA-TEIKD 137
++QS K + V+LL+I T + G +K+ A + D+AL T + D
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELG----RKRKAEE------DAALQAKKTRVSD 80
Query: 138 GLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVL 197
+ S +++ A T +++ + + + SS K+ A KA T++
Sbjct: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLP---SSMKEKA-KAETEKAGKTG 136
Query: 198 NIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV---SSRKKPAL 254
N G+ + S K P A S T + + E+ G+V + KP +
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEP------SANTTLVSETEEEGSVPAFGAAAKPGM 190
Query: 255 KATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRV 314
++ + DS S T D S KPA +KA+S V
Sbjct: 191 -VSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASS---------------------V 228
Query: 315 SSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEK 374
S+++ PA KA + ++T + K G PPA +A EE+S S E
Sbjct: 229 STKESPARKA-APAPGKVGDVTPQVKGGAL--------PPAKRAKKPEEESESSEEGSES 279
Query: 375 DGEKSRTVSSEQPPGLKVMKL 395
+ E S+ K++++
Sbjct: 280 EEEAPAGTRSQVKASEKILQV 300
Score = 38.5 bits (88), Expect = 0.011
Identities = 72/352 (20%), Positives = 129/352 (36%), Gaps = 37/352 (10%)
Query: 34 KEGPISGTVSSQKQPAEKATSDEKD------SVSNIATEIKEGQQSGTVSPQKQSAWKVI 87
K GP V ++KQ +++ +E D S + + T +K+ Q + + + K
Sbjct: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK-- 803
Query: 88 FKKKVSLLNIATRITGGGKSGTVSSQ-KQPASKATSDKTDSALNIATEIKDGLQCGTVSS 146
I+ GK T ++Q KQ + + N + +V
Sbjct: 804 -----------GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 147 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 206
A +A T E+ S + E D E+ +Q +P+ K T + + L A E
Sbjct: 853 AVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK--THQIRAALAPAKESPRK 909
Query: 207 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRK--KPALKATSDEKDSF 264
+ T + P+ ++DS S DGE V+S + KP L +
Sbjct: 910 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
Query: 265 SNITREKKDGEIS---RTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSS----- 316
+ S + SE A ++ E++ V+ + G +T V+
Sbjct: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP 1029
Query: 317 --RKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
K ++ S K+S +K++G ++ S+ L ATS + SV
Sbjct: 1030 RIAPKASMAGASSSKESSRISDGKKQEGPATQVDSA--VGTLPATSPQSTSV 1079
>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
Length = 1318
Score = 50.1 bits (118), Expect = 4e-06
Identities = 66/290 (22%), Positives = 117/290 (40%), Gaps = 48/290 (16%)
Query: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
K V+S + S+ +K + + L+ SS+ + +DEEDS
Sbjct: 492 KEKAVASPEATVSQTDENKARAEKKVTLSYSKNLK---PSSETKTQKGLFSDEEDSEDLF 548
Query: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
+++ K ++ K P + D+ED N+ K +T+S Q Q KA
Sbjct: 549 SSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFG--GTAAKKQTLSLQAQREEKA--- 603
Query: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDE-------KDSFSNITREKKDGEISR 278
K+ +S +K AL +SDE + ++ +R K + S
Sbjct: 604 ----------------KASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSG 647
Query: 279 TVTSEKPAGLKATS----DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS--- 331
T+ S++ +K TS D+ED + IA K+ +KT+RVS D+ DS
Sbjct: 648 TLQSQEAKAVKKTSLFEEDKEDDLFAIA--KDSQKKTQRVS-------LLFEDDVDSGGS 698
Query: 332 -FSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSR 380
F + + S+ PP L + +E+++ L + +K E ++
Sbjct: 699 LFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 748
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/406 (20%), Positives = 161/406 (39%), Gaps = 57/406 (14%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
SS+ + + SD++DS +++ ++ K P + D++D N+
Sbjct: 528 SSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTA 587
Query: 69 EGQQSGTVSPQKQSAWKV--IFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
+Q+ ++ Q++ K + KKK S L SS ++ A+
Sbjct: 588 AKKQTLSLQAQREEKAKASELSKKKASAL-------------LFSSDEEWNIPASQTHLA 634
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATT----DEEDSVSNIATEIK------------ 170
S E +D GT+ SQ+ A+K T+ D+ED + IA + +
Sbjct: 635 SDSRSKGEPRDS---GTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFED 691
Query: 171 DGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV 230
D + G++ ++ T ++++V + E+ + + K ++S+
Sbjct: 692 DVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESL 751
Query: 231 SIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKA 290
T++ + EK G ++ + +K D FS+ + K G RT T L
Sbjct: 752 KFGRTDVAESEKEGLLTRSAQETVK----HSDLFSSSSPWDK-GTKPRTKTV-----LSL 801
Query: 291 TSDEEDSV--LNI--ARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSR 346
+EED + NI A KE G+ + K + DE+ FS+ ++ D +
Sbjct: 802 FDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGV--FQDEELLFSHKLQKDNDPDVDL 859
Query: 347 TVSSQKPPALKAT------SDEEDSVLSIAREEK-DGEKSRTVSSE 385
++K L+ + DE+D + S A+ + EK R V +
Sbjct: 860 FAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKD 905
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 49.7 bits (117), Expect = 5e-06
Identities = 78/378 (20%), Positives = 149/378 (39%), Gaps = 34/378 (8%)
Query: 18 ATSDDKD-SVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTV 76
+T+D K + S++++E P +G+ ++ T+ S T G ++ T
Sbjct: 10 STADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTP 69
Query: 77 SPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIA---- 132
SP V +S I T T G ++ TVSS + A+ ++S ++ A
Sbjct: 70 SPTGSQTTIV----SISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSET 125
Query: 133 -TEIKDGLQCGTVSSQ-KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATT 190
T G + VS+ + +TT E +V++ A G ++ TVS+ A T
Sbjct: 126 TTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA-----GSETTTVSTVGSETTTAYT 180
Query: 191 DEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRK 250
+ ++ T G + TV + + +T ++ ++ G ++ TVS+
Sbjct: 181 ADSETTAASTT----GSEMTTVFTAGSETITPSTAGSETTTVSTA----GSETTTVSTTG 232
Query: 251 KPALKATSDEKDSFSNITREKKDGEISR--TVTSEKPAGLKAT-SDEEDSVLNIARGKED 307
A++ ++ + T + ++S + T+ AG + T + EDS N A ++
Sbjct: 233 SETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDS 292
Query: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
T + + A T E S + E T++S P S V
Sbjct: 293 KTTTASTTGFETTAASTTGSEPTMASTMGSE-------TTMASTIGPETTKVSTASSEVT 345
Query: 368 SIAREEKDGEKSRTVSSE 385
++ + ++ TV SE
Sbjct: 346 TVFAAGSETIRASTVGSE 363
Score = 42.0 bits (97), Expect = 0.001
Identities = 70/375 (18%), Positives = 137/375 (36%), Gaps = 39/375 (10%)
Query: 25 SVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAW 84
+VS +E I G+ +S T+ S T EG ++ TVS
Sbjct: 366 TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETT 425
Query: 85 KVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD------SALNIATEIKDG 138
V ++ T T G + VS+ + A+++ ++ S T +G
Sbjct: 426 TV----SITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEG 481
Query: 139 LQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLN 198
+ TV++ A T + S T G ++ TV + A+T+ ++
Sbjct: 482 SETTTVTTAGSETKTAYT----TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV 537
Query: 199 IATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIK------DGEKSGTVSSRKKP 252
AT G + TVS++ +T ++ ++ T ++ +G + TVS+
Sbjct: 538 SAT----GSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST---T 590
Query: 253 ALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTR 312
+ T+D + E + T++ +T+D E + G +T
Sbjct: 591 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT-----SASTTGSETT 645
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIARE 372
S+ A+++ ++ T D ET+ ++ + +T E + +S
Sbjct: 646 TASTTSSETTTASTEGSET---TTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 702
Query: 373 E----KDGEKSRTVS 383
E +G + TVS
Sbjct: 703 ETTVSTEGSGTTTVS 717
Score = 40.4 bits (93), Expect = 0.003
Identities = 70/372 (18%), Positives = 143/372 (38%), Gaps = 36/372 (9%)
Query: 15 AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSG 74
+E T S + ++TE G + +++ + T E + S +EI +G
Sbjct: 692 SETTTVSATGSETTVSTE-GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITG 750
Query: 75 TVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATE 134
+ + + + T G ++ T S+ TS +T A + +E
Sbjct: 751 SETTTASTEGSETTTASTEGSETTSASTTGSETTTAST--------TSSETTMASIMGSE 802
Query: 135 IKDGLQCGTVSSQKQPALK--ATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDE 192
G+ +++ A T E+S + IA+ ++ TVS+ + A+T
Sbjct: 803 TTMASTIGSETTKVSTASSKMTTVFTENSETTIAS--TTASETTTVSTAGSETIPASTAG 860
Query: 193 EDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKP 252
++ +T E SET ++ + + T E S + AT I G ++ T S+
Sbjct: 861 SETTTTTST-----EGSETTTASTEGSETTTASTESSETTTATTI--GSETTTASTE--- 910
Query: 253 ALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTR 312
+ T+ + T + EI+ T+ +T E + +G +
Sbjct: 911 GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTT-----ASTEGSELT 965
Query: 313 RVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIARE 372
VS+ + +++ ++ + +T + T+ T S+ +T+ E + SI
Sbjct: 966 TVSTTGSETITVSAEGSET-TTVTTMGSETTTASTAGSETTTV--STAGSETTTASI--- 1019
Query: 373 EKDGEKSRTVSS 384
+G ++ TVSS
Sbjct: 1020 --EGSETTTVSS 1029
Score = 35.8 bits (81), Expect = 0.070
Identities = 50/245 (20%), Positives = 89/245 (36%), Gaps = 16/245 (6%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
S+ + +T + +VS TE G+ ++ A T+ + S T
Sbjct: 1018 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1077
Query: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
EG ++ TVS S ++ T SGT ++ + T T
Sbjct: 1078 STEGSETTTVSTTGSET------TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITG 1131
Query: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
S A+ +G + TVS+ A+T + ++ + T + + T+ S+ +
Sbjct: 1132 SKTTTAS--TEGSEATTVSTTSSETTTASTTGSE-MTTVFTTVSETTTVSTIGSEATTSS 1188
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKA---TTDEEDSVSIIATEIKDGEKS 243
A ++ +TE + + T S+ A A TT S S T G ++
Sbjct: 1189 AAGSE----ATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1244
Query: 244 GTVSS 248
T SS
Sbjct: 1245 STPSS 1249
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 49.3 bits (116), Expect = 6e-06
Identities = 66/304 (21%), Positives = 124/304 (40%), Gaps = 29/304 (9%)
Query: 105 GKSGTVSSQKQPASKATSDKTDS---ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 161
G T ++P + + + + N+A + L+ T +Q+ A +A+T+ ++
Sbjct: 168 GSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEASAARASTETSNA 227
Query: 162 -VSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATE-IKDGEKSETVSSQKQPA 219
S A++ + + S+ K+ + D+E S + E ++ KSE S P
Sbjct: 228 KTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPV 287
Query: 220 --LKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEIS 277
+K T E +++ ++ +++ S K K S+EK +EK + +
Sbjct: 288 EEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFD 347
Query: 278 RTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITR 337
+ SE +K DE+ + +++ E + S + K K+ FS I
Sbjct: 348 HSKKSEDTQKVK---DEKQAK------EKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDS 398
Query: 338 EKKDGETSRTVSSQKPPALKA----------TSD--EEDSVLSIAREEKDGEKSRTVSSE 385
+ DG T TVSS L + TSD EE + S E+ K++T +S+
Sbjct: 399 DV-DGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSD 457
Query: 386 QPPG 389
G
Sbjct: 458 SSEG 461
Score = 43.5 bits (101), Expect = 3e-04
Identities = 82/381 (21%), Positives = 146/381 (38%), Gaps = 41/381 (10%)
Query: 27 SNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQ----SGTVSPQKQS 82
+ + TE E P+ VS + S+EKD + I+T I E + S T +S
Sbjct: 2108 TRVTTEEFEAPMPSAVSGDDSQLTASRSEEKDECAMISTSIGEEFELPISSATTIKCAES 2167
Query: 83 AWKV---IFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL 139
V + ++ + I+T G + P + + ++ D I+T I +
Sbjct: 2168 LQPVAAAVEERATGPVLISTADFEGPMPSAPPEAESPLASTSKEEKDECALISTSIAEEC 2227
Query: 140 QC---GTVSSQKQPALKATTDEEDSVSNIAT-EIKDGEKSGTVSSQKQPALKATTDEEDS 195
+ G V + +E+D I+T ++D E G VSS +E D
Sbjct: 2228 EASVSGVVVESENERAGTVMEEKDGSGIISTSSVEDCE--GPVSS------AVPQEEGDP 2279
Query: 196 VLNIATEIKDGEKSETVSSQKQPA--LKATTDEEDSVSIIATE-IKDGEKSGTVSSRKKP 252
+ A E+ D T +S+ A + A +ED ++I E + D T ++ P
Sbjct: 2280 SVTPAEEMGDTAMISTSTSEGCEAVMIGAVLQDEDRLTITRVEDLSDAAIISTSTAECMP 2339
Query: 253 ALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVL--NIARGKEDG-- 308
+ +++ + +G++S T S+ + + E + + GKE G
Sbjct: 2340 ISASIDRHEENQLTADNPEGNGDLSATEVSKHKVPMPSLIAENNCRCPGPVRGGKEPGPV 2399
Query: 309 -----EKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVS-----SQKPPALKA 358
E+ S KP + S +E+K G+ + QK L
Sbjct: 2400 LAVSTEEGHNGPSVHKP---SAGQGHPSAVCAEKEEKHGKECPEIGPFAGRGQKESTLHL 2456
Query: 359 TSDEEDSVL--SIAREEKDGE 377
+ EE +VL S+ +E+K E
Sbjct: 2457 INAEEKNVLLNSLQKEDKSPE 2477
Score = 42.4 bits (98), Expect = 7e-04
Identities = 81/400 (20%), Positives = 149/400 (37%), Gaps = 58/400 (14%)
Query: 18 ATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVS 77
A ++ DS+S K+ I + + + + KD V+ + EG + S
Sbjct: 1926 ANENNVDSMSGTEKGSKDTDICSSAKGIVESSVTSAVSGKDEVTPVPGGC-EGPMTSAAS 1984
Query: 78 PQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQK---QPASKATSDKTDSAL--NIA 132
Q S + KV I+T + GG VS + + A + S+K D + ++
Sbjct: 1985 DQSDSQLE-----KVEDTTISTGLVGGSYDVLVSGEVPECEVAHTSPSEKEDEDIITSVE 2039
Query: 133 TEIKDGLQCGTVS-------------SQKQPALKATTDEEDSVSNIA--TEIKDGEKSGT 177
E DGL T S +Q + + +T+ D ++ T+++ G
Sbjct: 2040 NEECDGLMATTASGDITNQNSLAGGKNQGKVLIISTSTTNDYTPQVSAITDVEGGLSDAL 2099
Query: 178 VSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD--EEDSVSI-IA 234
+ + + TT+E ++ + A D + + + S +K +T EE + I A
Sbjct: 2100 RTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTASRSEEKDECAMISTSIGEEFELPISSA 2159
Query: 235 TEIKDGEKSGTVSSRKK-----PALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLK 289
T IK E V++ + P L +T+D + + E + S + + L
Sbjct: 2160 TTIKCAESLQPVAAAVEERATGPVLISTADFEGPMPSAPPEAESPLASTSKEEKDECALI 2219
Query: 290 ATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDG----ETS 345
+TS E+ +++ + E R + E+KDG TS
Sbjct: 2220 STSIAEECEASVSGVVVESENER--------------------AGTVMEEKDGSGIISTS 2259
Query: 346 RTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSE 385
+ P + +E D ++ A E D T +SE
Sbjct: 2260 SVEDCEGPVSSAVPQEEGDPSVTPAEEMGDTAMISTSTSE 2299
Score = 38.1 bits (87), Expect = 0.014
Identities = 49/214 (22%), Positives = 84/214 (39%), Gaps = 16/214 (7%)
Query: 13 QPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK---E 69
QP A + I+T EGP+ + P + +EKD + I+T I E
Sbjct: 2169 QPVAAAVEERATGPVLISTADFEGPMPSAPPEAESPLASTSKEEKDECALISTSIAEECE 2228
Query: 70 GQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKAT-SDKTDSA 128
SG V + + ++K I+T +V + P S A ++ D +
Sbjct: 2229 ASVSGVVVESENERAGTVMEEKDGSGIIST--------SSVEDCEGPVSSAVPQEEGDPS 2280
Query: 129 LNIATEIKDGLQCGTVSSQKQPA--LKATTDEEDSVSNIATE-IKDGEKSGTVSSQKQPA 185
+ A E+ D T +S+ A + A +ED ++ E + D T +++ P
Sbjct: 2281 VTPAEEMGDTAMISTSTSEGCEAVMIGAVLQDEDRLTITRVEDLSDAAIISTSTAECMPI 2340
Query: 186 LKATTDEEDSVLNIATEIKDGEKSET-VSSQKQP 218
+ E++ L +G+ S T VS K P
Sbjct: 2341 SASIDRHEENQLTADNPEGNGDLSATEVSKHKVP 2374
Score = 37.7 bits (86), Expect = 0.018
Identities = 81/362 (22%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 9 SSQKQPAEKATSDDKDSVSNIATEI---KEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 65
S +K EK S+DK SV + K G + SS+K + ++ + +++
Sbjct: 724 SKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSS 783
Query: 66 EIKEGQQSGTVSPQKQSAWKVIFK--KKVSLLNIAT----RITGGGKSGTVSSQKQPASK 119
+ K ++S + +K S V+ K K VS I T R K +S++K A
Sbjct: 784 DDKTERKSKHRNERKLS---VLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEH 840
Query: 120 ATSDKTDSALNIATEIKDGL---QCGTVSSQKQPAL---KATTDEEDSVSNIATEI---K 170
+ +DS + KD L Q G ++ + K D + SN+ E K
Sbjct: 841 KSRRSSDSKIQ-----KDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHK 895
Query: 171 DGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV 230
+ ++ ++ +K + + V + TE+++G + + + P + T+E DS
Sbjct: 896 EKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPK--PDKEKNTEENDSE 953
Query: 231 SIIATEIKDG--EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKP-AG 287
++++D E++G + + A S +KDS ++ P A
Sbjct: 954 KQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHR---------------AKLPLAK 998
Query: 288 LKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKA---TSDEKDSFS-NITREKKDGE 343
K SD++ + + R DG K+R + K K SD+KD + + EK G
Sbjct: 999 EKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGN 1058
Query: 344 TS 345
+S
Sbjct: 1059 SS 1060
Score = 37.7 bits (86), Expect = 0.018
Identities = 55/281 (19%), Positives = 113/281 (40%), Gaps = 35/281 (12%)
Query: 110 VSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEI 169
+ Q Q ++ DKT+ E K + +P + +++V
Sbjct: 772 IQKQSQQTKLSSDDKTERKSKHRNERK----LSVLGKDGKPVSEYIIKTDENVRK----- 822
Query: 170 KDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKD--GEKSETVSSQKQPALKATTDEE 227
++ +K +S++K A + DS + KD G K ++ Q+ ++ + E
Sbjct: 823 ENNKKERRLSAEKTKAEHKSRRSSDSKIQ-----KDSLGSKQHGITLQR----RSESYSE 873
Query: 228 DSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAG 287
D + +T + K V ++K K+ +EK + + K G+ + V +E G
Sbjct: 874 DKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKS--KSKTQGKQVKVVETELQEG 931
Query: 288 L--KATSDEEDSVLNIARGKEDGEKTRRVSSRKKP----ALKATSDEKDSFSNITREKKD 341
+AT+ + D N + D EK R+ KP ++ + S ++ T++
Sbjct: 932 ATKQATTPKPDKEKNTE--ENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSS 989
Query: 342 GETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTV 382
++ +K SD++ + + R+ DG KSR++
Sbjct: 990 HRAKLPLAKEK-----YKSDKDSTSTRLERKLSDGHKSRSL 1025
Score = 34.7 bits (78), Expect = 0.16
Identities = 88/401 (21%), Positives = 156/401 (38%), Gaps = 69/401 (17%)
Query: 37 PISGTVSSQK-QPAEKATSDEKDSVSNIATEIKEGQQSG-----TVSPQKQSAWKVIFKK 90
P+ GTV+ PAE+ S+ D++ T+ GQ+S T+ P + ++ K
Sbjct: 2541 PVQGTVAEHSFLPAEQQGSE--DNLKTSTTKCITGQESKIAPSHTMIPPATYSVALLAPK 2598
Query: 91 KVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 150
L I +G Q +++ T D + + E G TVSS++
Sbjct: 2599 CEQDLTIKNDYSGKWTD-------QASAEKTGDDNSTRKSFPEE---GDIMVTVSSEENV 2648
Query: 151 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDS-VLNIATEIKDGEKS 209
E+S N+ +K ++ K A + +E++ +L + G+ S
Sbjct: 2649 C---DIGNEESPLNVLGGLK------LKANLKMEAYVPSEEEKNGEILAPPESLCGGKPS 2699
Query: 210 ETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITR 269
Q++P L +S+++ + + E+ + S K D ++ S +
Sbjct: 2700 GIAELQREPLLV-----NESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSV 2754
Query: 270 EKKDGEIS---RTVTSEKPAGLKATSDEE--------DSVLNIARGK---EDGEKTRRVS 315
E E+ R + K +S++E DS + A+ + + T+ +
Sbjct: 2755 EADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEEN 2814
Query: 316 SRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPAL---KATSDEEDSVLSIARE 372
SR L TS E +S ++ E+KD +S + +KP S EED + I R+
Sbjct: 2815 SRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRK 2874
Query: 373 E--------------KDGEKSRT--VSSEQPPG---LKVMK 394
KD K+ T V+ EQ P LKVM+
Sbjct: 2875 RGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQ 2915
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 48.5 bits (114), Expect = 1e-05
Identities = 81/357 (22%), Positives = 133/357 (37%), Gaps = 58/357 (16%)
Query: 33 IKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKV 92
I EGP + + +K PAE S E +N E+K V Q+++ K + ++
Sbjct: 60 INEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVK-------VESQREAGGKEDAEAEL 112
Query: 93 SLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPAL 152
+ G + TV SQ+ K ++T S A E + T++S+KQ
Sbjct: 113 K------KEDGEKEETTVGSQEMTGRK---EETKSEPKEAEEKE-----STLASEKQ--- 155
Query: 153 KATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETV 212
KA E S + D +K P KAT +EED+ A++ + G++ E
Sbjct: 156 KAEEKEAKPESGQKADANDRDK---------PEPKATVEEEDA--KTASQEETGQRKECS 204
Query: 213 SSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK 272
+ K+ A E +++ E K K K K +D K+ E +
Sbjct: 205 TEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKE-------EAE 257
Query: 273 DGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSF 332
D E E G + E+D + + E G S + P S
Sbjct: 258 DAE-------EAEPGSPSEEQEQD----VEKEPEGGAGVIPSSPEEWPESPTGEGHNLST 306
Query: 333 SNITRE-KKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPP 388
+ + G+TS + S P + + E S + E+K+ R VS+ P
Sbjct: 307 DGLGPDCVASGQTSPSASESSPSDVPQSPPESPS----SGEKKEKAPERRVSAPARP 359
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/233 (21%), Positives = 87/233 (37%), Gaps = 19/233 (8%)
Query: 159 EDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQP 218
E++ I +G + + +K PA + E N E+K + E +
Sbjct: 50 EETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAE 109
Query: 219 ALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKAT--SDEKDSFSNITREKKDGEI 276
A D E + + ++ G K T S K+ K + + EK + + G+
Sbjct: 110 AELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQK 169
Query: 277 SRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNIT 336
+ +KP KAT +EED A+ E +R +P KAT +E +
Sbjct: 170 ADANDRDKPEP-KATVEEED-----AKTASQEETGQRKECSTEPKEKATDEEAKA----- 218
Query: 337 REKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPG 389
E+ + V + A D ++ A+EE D ++ + E PG
Sbjct: 219 ------ESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPG 265
Score = 42.4 bits (98), Expect = 7e-04
Identities = 61/316 (19%), Positives = 118/316 (37%), Gaps = 26/316 (8%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
S +K PAE S + +N E+K + AE D + + + ++
Sbjct: 68 SGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQ 127
Query: 67 IKEGQQSGTVSPQKQSAWK--VIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
G++ T S K++ K + +K + G K+ + + +P KAT ++
Sbjct: 128 EMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKA-DANDRDKPEPKATVEE 186
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
D+ E +C T +P KAT +E + S A + + K+
Sbjct: 187 EDAKTASQEETGQRKECST-----EPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEE 241
Query: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
A +E D+ E +D E++E S ++ + E +I + ++ +S
Sbjct: 242 AKHGAKEEADA----KEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESP 297
Query: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
T L D ++ G+ S + + P+ + + E S +
Sbjct: 298 TGEGHN---LSTDGLGPDCVAS-------GQTSPSASESSPSDVPQSPPESPS----SGE 343
Query: 305 KEDGEKTRRVSSRKKP 320
K++ RRVS+ +P
Sbjct: 344 KKEKAPERRVSAPARP 359
>gi|109637761 calpastatin isoform g [Homo sapiens]
Length = 772
Score = 48.1 bits (113), Expect = 1e-05
Identities = 92/411 (22%), Positives = 149/411 (36%), Gaps = 49/411 (11%)
Query: 13 QPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQ 72
QP +K + + + A E T S +P EK SDEK + S +++
Sbjct: 3 QPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYA 62
Query: 73 SGTVSPQKQSAWKVIFKKKVSL-------LNIATRITGGGKSGTVSSQKQ-----PASKA 120
GT S K SA K S+ + ++ ++ G +KQ P K+
Sbjct: 63 GGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKS 122
Query: 121 TSDKTDS----ALNIATEIKDGLQCGTVSSQKQPALKAT---TDEEDSVS----NIATEI 169
S K S A + + + + S+++QP+ K+T T +D +S ++A
Sbjct: 123 QSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGIT 182
Query: 170 KDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDS 229
K G +K+ A E D + + + P EE++
Sbjct: 183 AISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGP----EETEEEN 238
Query: 230 VSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLK 289
+ E+ D S + K + ++ + KK+G S KP G
Sbjct: 239 TTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLA-----KKEGITGPPADSSKPIGPD 293
Query: 290 ATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVS 349
D S G+KT + S + LKA S + +EKK T+S
Sbjct: 294 DAIDALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMS 351
Query: 350 SQKPPALKAT-----SDEEDSVLSI-------ARE---EKDGEKSRTVSSE 385
Q AL A+ ++ E + SI A+E EK GE T+ SE
Sbjct: 352 DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSE 402
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 47.4 bits (111), Expect = 2e-05
Identities = 94/401 (23%), Positives = 161/401 (40%), Gaps = 48/401 (11%)
Query: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGP-ISGTVSSQKQPA-EKATSDEKDSVSNIA 64
SV +K E S K S++ T KE + +++ +K+P+ E+A
Sbjct: 331 SVLQEKHTTEHEMSILKKSLALQKTNFKEDSLVKESLAFKKKPSTEEAIMMPVILKEQCM 390
Query: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
TE K + V + S K + K +S+ + + S ++P++
Sbjct: 391 TEGKRSRLKPLVLQEITSGEKSLIMKPLSIKEKPS-------TEKESFSQEPSALQKKHT 443
Query: 125 TDSALNIATEIKDGLQCGTVSSQKQPAL----KATTDEEDSVSNIATEIKDGEKSGTVSS 180
T ++I E L+ T S AL K T +E + GT+S
Sbjct: 444 TQEEVSILKEPSSLLKSPTEESPFDEALAFTKKCTIEEAPPTKKPLILKRKHATQGTMSH 503
Query: 181 QKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKD- 239
K+P + TT E S++ K+ E VS +K K TT E S+ + +D
Sbjct: 504 LKKPLILQTTSGEKSLIKEPLPFKE----EKVSLKK----KCTTQEMMSICPELLDFQDM 555
Query: 240 -GEKSGT-----VSSRKKPALKATSDEKDSFSNITREKKDGEIS--------RTVTSEK- 284
GE + +S RK P + T K S S ++ G++S + +TSE+
Sbjct: 556 IGEDKNSFFMEPMSFRKNPTTEETVLTKTSLSLQEKKITQGKMSHLKKPLVLQKITSEEE 615
Query: 285 -------PAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPAL---KATSDEKDSFSN 334
P +K+T++E+ + KE + VS K+ KAT++E+ S
Sbjct: 616 SFYKKLLPFKMKSTTEEKFLSQEPSALKEKHTTLQEVSLSKESLAIQEKATTEEEFSQEL 675
Query: 335 ITREKKDGETSRTVSSQKPPALKATSDEEDSVLS-IAREEK 374
+ K S ++ + + T EEDS+ + +A +EK
Sbjct: 676 FSLHVKHTNKSGSLFQEALVLQEKTDAEEDSLKNLLALQEK 716
Score = 40.0 bits (92), Expect = 0.004
Identities = 77/377 (20%), Positives = 155/377 (41%), Gaps = 44/377 (11%)
Query: 42 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSP---QKQSAWKVIFKKKVSLLNIA 98
+S +K P + T K S+S +I +G+ S P QK ++ + F KK LL
Sbjct: 568 MSFRKNPTTEETVLTKTSLSLQEKKITQGKMSHLKKPLVLQKITSEEESFYKK--LLPFK 625
Query: 99 TRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 158
+ T K ++P++ T ++++ E +++ Q+ KATT+E
Sbjct: 626 MKSTTEEKF----LSQEPSALKEKHTTLQEVSLSKE--------SLAIQE----KATTEE 669
Query: 159 EDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQP 218
E S + +K KSG++ + + T EEDS+ N+ + E K
Sbjct: 670 EFSQELFSLHVKHTNKSGSLFQEALVLQEKTDAEEDSLKNLLALQEKSTMEEESLINKLL 729
Query: 219 ALKATTDEEDSVSI---IATEIKDGEKSGTVSSRKKPALKATSDEKDSFS---------- 265
ALK E + +I ++ + K +K+ AL T +E++ +
Sbjct: 730 ALKEELSAEAATNIQTQLSLKKKSTSHGKVFFLKKQLALNETINEEEFLNKQPLALEGYP 789
Query: 266 ----NITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPA 321
T KK + + EK A LK + + ++ ++ T + + K+P+
Sbjct: 790 SIAEGETLFKKLLAMQEEPSIEKEAVLKEPTIDTEAHFKEPLALQEEPSTEKEAVLKEPS 849
Query: 322 LKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL--SIAREEKDGEKS 379
+ + K++ + ++K + + + S E++++ S+ +EK K
Sbjct: 850 VDTEAHFKET---LALQEKPSIEQEALFKRHSALWEKPSTEKETIFKESLDLQEKPSIKK 906
Query: 380 RTVSSEQPPGLKVMKLS 396
T+ ++P LK+ ++
Sbjct: 907 ETL-LKKPLALKMSTIN 922
Score = 37.0 bits (84), Expect = 0.031
Identities = 79/364 (21%), Positives = 149/364 (40%), Gaps = 56/364 (15%)
Query: 16 EKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGT 75
EKAT++++ S + +K SG++ + ++ T E+DS+ N+ Q+ T
Sbjct: 663 EKATTEEEFSQELFSLHVKHTNKSGSLFQEALVLQEKTDAEEDSLKNLLAL----QEKST 718
Query: 76 VSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEI 135
+ + SL+N + ++ A AT+ +T +L
Sbjct: 719 MEEE-------------SLINKLLAL----------KEELSAEAATNIQTQLSLK----- 750
Query: 136 KDGLQCGTV-SSQKQPALKATTDEEDSVSN--IATE----IKDGEK--SGTVSSQKQPAL 186
K G V +KQ AL T +EE+ ++ +A E I +GE ++ Q++P++
Sbjct: 751 KKSTSHGKVFFLKKQLALNETINEEEFLNKQPLALEGYPSIAEGETLFKKLLAMQEEPSI 810
Query: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPAL-KATTDEEDSV-------SIIATEIK 238
E+++VL T + E ++ Q++P+ K +E SV +A + K
Sbjct: 811 -----EKEAVLKEPTIDTEAHFKEPLALQEEPSTEKEAVLKEPSVDTEAHFKETLALQEK 865
Query: 239 DGEKSGTVSSRKKPALKATSDEKDS-FSNITREKKDGEISRTVTSEKPAGLKATSDEEDS 297
+ + R + S EK++ F ++ I + +KP LK ++ E
Sbjct: 866 PSIEQEALFKRHSALWEKPSTEKETIFKESLDLQEKPSIKKETLLKKPLALKMSTINEAV 925
Query: 298 VLNIARGKEDGEKTRRVSSRKKP-ALKATSDEKDSFSNITREKKDGETSRTVSSQKPPAL 356
+ + T + S K+P AL+ + K+ T TS VSS P ++
Sbjct: 926 LFEDMIALNEKPTTGKELSFKEPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESI 985
Query: 357 KATS 360
+ S
Sbjct: 986 TSKS 989
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.298 0.116 0.294
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,227,700
Number of Sequences: 37866
Number of extensions: 622613
Number of successful extensions: 3779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 387
Number of HSP's that attempted gapping in prelim test: 2488
Number of HSP's gapped (non-prelim): 1145
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.