SGEF 11115

Name: SGEF	Sequence: fasta or formatted (871aa)		NCBI GI: 194473700
Description: Src homology 3 domain-containing guanine nucleotide exchange factor		Referenced in: Rho and Rac
Composition: Amino acid Percentage Count Longest homopolymer A alanine 5.4 47 2 C cysteine 1.1 10 1 D aspartate 4.5 39 2 E glutamate 7.9 69 2 F phenylalanine 2.9 25 2 G glycine 5.1 44 2 H histidine 1.7 15 2 I isoleucine 4.0 35 2 K lysine 7.3 64 3 L leucine 9.8 85 3 M methionine 2.0 17 2 N asparagine 4.2 37 2 P proline 7.2 63 5 Q glutamine 4.6 40 2 R arginine 6.8 59 3 S serine 11.0 96 3 T threonine 5.4 47 1 V valine 6.3 55 2 W tryptophan 0.7 6 1 Y tyrosine 2.1 18 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 Src homology 3 domain-containing guanine nucleotide... ARHGEF16 0.286 Rho guanine exchange factor 16 NGEF 0.172 neuronal guanine nucleotide exchange factor isoform... NGEF 0.172 neuronal guanine nucleotide exchange factor isoform... ARHGEF5 0.155 rho guanine nucleotide exchange factor 5 ARHGEF19 0.142 Rho guanine nucleotide exchange factor (GEF) 19 [Hom... ARHGEF15 0.128 Rho guanine exchange factor 15 ITSN1 0.053 intersectin 1 isoform ITSN-l ITSN2 0.051 intersectin 2 isoform 3 ITSN2 0.051 intersectin 2 isoform 1 PLEKHG5 0.044 pleckstrin homology domain containing family G membe... PLEKHG5 0.044 pleckstrin homology domain containing family G memb... PLEKHG5 0.044 pleckstrin homology domain containing family G memb... PLEKHG5 0.044 pleckstrin homology domain containing family G memb... PLEKHG5 0.044 pleckstrin homology domain containing family G memb... FGD4 0.036 FYVE, RhoGEF and PH domain containing 4 FGD2 0.036 FYVE, RhoGEF and PH domain containing 2 ARHGEF12 0.035 Rho guanine nucleotide exchange factor (GEF) 12 [Homo... NET1 0.034 neuroepithelial cell transforming gene 1 isoform 1 ... NET1 0.032 neuroepithelial cell transforming gene 1 isoform 2 [... ARHGEF11 0.032 Rho guanine nucleotide exchange factor (GEF) 11 isof... ARHGEF11 0.032 Rho guanine nucleotide exchange factor (GEF) 11 isofo... FGD1 0.032 faciogenital dysplasia protein ARHGEF4 0.031 Rho guanine nucleotide exchange factor 4 isoform b [... ECT2 0.029 epithelial cell transforming sequence 2 oncogene pro... ARHGEF4 0.029 Rho guanine nucleotide exchange factor 4 isoform a [... PREX1 0.029 phosphatidylinositol-3,4,5-trisphosphate-dependent R... PLEKHG6 0.029 pleckstrin homology domain-containing family G memb... PLEKHG6 0.029 pleckstrin homology domain-containing family G memb... PLEKHG6 0.029 pleckstrin homology domain-containing family G memb... Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.