Guide to the Human Genome
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Search of human proteins with 239747524

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747524 PREDICTED: similar to serum response
factor-related protein C4 [Homo sapiens]
         (434 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239747524 PREDICTED: similar to serum response factor-related...   889   0.0  
gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]      380   e-105
gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]      317   2e-86
gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]      315   4e-86
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]      312   3e-85
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...   254   1e-67
gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens]      188   7e-48
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                  172   7e-43
gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]       149   4e-36
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ...   149   4e-36
gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Hom...   147   2e-35
gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Hom...   147   2e-35
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...   138   1e-32
gi|169203146 PREDICTED: similar to heterogeneous nuclear ribonuc...   132   5e-31
gi|89035135 PREDICTED: similar to heterogeneous nuclear ribonucl...   132   6e-31
gi|89034333 PREDICTED: similar to heterogeneous nuclear ribonucl...   132   6e-31
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...   126   4e-29
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...   126   4e-29
gi|55956899 keratin 9 [Homo sapiens]                                   88   1e-17
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    85   1e-16
gi|195972866 keratin 10 [Homo sapiens]                                 83   4e-16
gi|109255251 loricrin [Homo sapiens]                                   79   6e-15
gi|119395750 keratin 1 [Homo sapiens]                                  79   1e-14
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           79   1e-14
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          79   1e-14
gi|47132620 keratin 2 [Homo sapiens]                                   75   2e-13
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    72   1e-12
gi|109452587 family with sequence similarity 98, member B isofor...    72   1e-12
gi|186928827 dermokine isoform 5 precursor [Homo sapiens]              64   3e-10
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]              63   5e-10

>gi|239747524 PREDICTED: similar to serum response factor-related
           protein C4 [Homo sapiens]
          Length = 434

 Score =  889 bits (2298), Expect = 0.0
 Identities = 434/434 (100%), Positives = 434/434 (100%)

Query: 1   MPESQSSNNSLTPNTRSIIKVSLLPAVLSNSESPKEPKQLRKLFLGRGDGYNGFGNDGGY 60
           MPESQSSNNSLTPNTRSIIKVSLLPAVLSNSESPKEPKQLRKLFLGRGDGYNGFGNDGGY
Sbjct: 1   MPESQSSNNSLTPNTRSIIKVSLLPAVLSNSESPKEPKQLRKLFLGRGDGYNGFGNDGGY 60

Query: 61  GGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYN 120
           GGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYN
Sbjct: 61  GGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYN 120

Query: 121 DFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSSRHYQDVLASP 180
           DFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSSRHYQDVLASP
Sbjct: 121 DFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSSRHYQDVLASP 180

Query: 181 KLKEAAPGSAERWRRAQAAAYIVEALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEF 240
           KLKEAAPGSAERWRRAQAAAYIVEALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEF
Sbjct: 181 KLKEAAPGSAERWRRAQAAAYIVEALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEF 240

Query: 241 DNMMQNHNIAPGLPPQNFSMSVTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSP 300
           DNMMQNHNIAPGLPPQNFSMSVTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSP
Sbjct: 241 DNMMQNHNIAPGLPPQNFSMSVTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSP 300

Query: 301 PQTILHRNVSPGAPQRPPSTGNAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGAT 360
           PQTILHRNVSPGAPQRPPSTGNAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGAT
Sbjct: 301 PQTILHRNVSPGAPQRPPSTGNAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGAT 360

Query: 361 GANSLGKVMPTKSPPPPGGSNLGMNSGKPDLRVVIPASSKGMTPPLELKSERKRESSILS 420
           GANSLGKVMPTKSPPPPGGSNLGMNSGKPDLRVVIPASSKGMTPPLELKSERKRESSILS
Sbjct: 361 GANSLGKVMPTKSPPPPGGSNLGMNSGKPDLRVVIPASSKGMTPPLELKSERKRESSILS 420

Query: 421 TNEFIKVYQMLIPQ 434
           TNEFIKVYQMLIPQ
Sbjct: 421 TNEFIKVYQMLIPQ 434


>gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]
          Length = 499

 Score =  380 bits (976), Expect = e-105
 Identities = 188/205 (91%), Positives = 191/205 (93%)

Query: 202 IVEALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQNFSMS 261
           IVEALNKKEHRGCDS DPDTS VLTP+TEEKYKKINEEFDNMM+NH IAPGLPPQNFSMS
Sbjct: 84  IVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMS 143

Query: 262 VTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRNVSPGAPQRPPSTG 321
           VTVPV SPNALSYTNPGSSLVSPSLAASSTLTD + LSPPQT LHRNVSPGAPQRPPSTG
Sbjct: 144 VTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTG 203

Query: 322 NAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGSN 381
           NAGGML TTDLTVPNG GSSPVGN FVNSRASPNLIGATGANSLGKVMPTKSPPPPGG N
Sbjct: 204 NAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGN 263

Query: 382 LGMNSGKPDLRVVIPASSKGMTPPL 406
           LGMNS KPDLRVVIP SSKGM PPL
Sbjct: 264 LGMNSRKPDLRVVIPPSSKGMMPPL 288


>gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]
          Length = 497

 Score =  317 bits (811), Expect = 2e-86
 Identities = 161/205 (78%), Positives = 172/205 (83%), Gaps = 2/205 (0%)

Query: 202 IVEALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQNFSMS 261
           IVE L KK   GC+S D D     +P +E+++ K+NE+ D + +     PGLPPQNFSMS
Sbjct: 84  IVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRG--PPGLPPQNFSMS 141

Query: 262 VTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRNVSPGAPQRPPSTG 321
           VTVPV SPNALSYTNPGSSLVSPSLAASSTLTD + LSPPQT LHRNVSPGAPQRPPSTG
Sbjct: 142 VTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTG 201

Query: 322 NAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGSN 381
           NAGGML TTDLTVPNG GSSPVGN FVNSRASPNLIGATGANSLGKVMPTKSPPPPGG N
Sbjct: 202 NAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGN 261

Query: 382 LGMNSGKPDLRVVIPASSKGMTPPL 406
           LGMNS KPDLRVVIP SSKGM PPL
Sbjct: 262 LGMNSRKPDLRVVIPPSSKGMMPPL 286


>gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]
          Length = 437

 Score =  315 bits (808), Expect = 4e-86
 Identities = 160/220 (72%), Positives = 179/220 (81%), Gaps = 2/220 (0%)

Query: 204 EALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQNFSMSVT 263
           + L KK   GC+S D D     +P +E+++ K+NE+ D + +     PGLPPQNFSMSVT
Sbjct: 18  QTLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRG--PPGLPPQNFSMSVT 75

Query: 264 VPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRNVSPGAPQRPPSTGNA 323
           VPV SPNALSYTNPGSSLVSPSLAASSTLTD + LSPPQT LHRNVSPGAPQRPPSTGNA
Sbjct: 76  VPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNA 135

Query: 324 GGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGSNLG 383
           GGML TTDLTVPNG GSSPVGN FVNSRASPNLIGATGANSLGKVMPTKSPPPPGG NLG
Sbjct: 136 GGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLG 195

Query: 384 MNSGKPDLRVVIPASSKGMTPPLELKSERKRESSILSTNE 423
           MNS KPDLRVVIP SSKGM PPL  + E +  +  +S+++
Sbjct: 196 MNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQ 235


>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
          Length = 429

 Score =  312 bits (800), Expect = 3e-85
 Identities = 158/203 (77%), Positives = 170/203 (83%), Gaps = 2/203 (0%)

Query: 204 EALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQNFSMSVT 263
           + L KK   GC+S D D     +P +E+++ K+NE+ D + +     PGLPPQNFSMSVT
Sbjct: 18  QTLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRG--PPGLPPQNFSMSVT 75

Query: 264 VPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRNVSPGAPQRPPSTGNA 323
           VPV SPNALSYTNPGSSLVSPSLAASSTLTD + LSPPQT LHRNVSPGAPQRPPSTGNA
Sbjct: 76  VPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNA 135

Query: 324 GGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGSNLG 383
           GGML TTDLTVPNG GSSPVGN FVNSRASPNLIGATGANSLGKVMPTKSPPPPGG NLG
Sbjct: 136 GGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLG 195

Query: 384 MNSGKPDLRVVIPASSKGMTPPL 406
           MNS KPDLRVVIP SSKGM PPL
Sbjct: 196 MNSRKPDLRVVIPPSSKGMMPPL 218


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  254 bits (648), Expect = 1e-67
 Identities = 114/128 (89%), Positives = 118/128 (92%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSF 105
           G GDGYNGFGNDGGYGGGGPGYSGGSRGYGS GQGYG+QGSGYGGSGSY+SYNNGGGG F
Sbjct: 239 GSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGF 298

Query: 106 GGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYG 165
           GGGSGS+FGG GSYNDFGNYNNQSSNFGP KGGNFGGRSS P GGGGQYF KP+NQGGYG
Sbjct: 299 GGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYG 358

Query: 166 GSSSSRHY 173
           GSSSS  Y
Sbjct: 359 GSSSSSSY 366



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 13/88 (14%)

Query: 91  SGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGG 150
           S S +     G G+FGGG G  FGG+ ++   GN++ +    G   GG +GG      G 
Sbjct: 188 SASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGF 247

Query: 151 GGQYFVKPQNQGGYGG-----SSSSRHY 173
           G        N GGYGG     S  SR Y
Sbjct: 248 G--------NDGGYGGGGPGYSGGSRGY 267



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 15/19 (78%), Positives = 18/19 (94%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S SESPKEP+QLRKLF+G
Sbjct: 1  MSKSESPKEPEQLRKLFIG 19


>gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens]
          Length = 463

 Score =  188 bits (478), Expect = 7e-48
 Identities = 110/220 (50%), Positives = 144/220 (65%), Gaps = 20/220 (9%)

Query: 202 IVEALNKKEHRGCDSSDPDTSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQNFSMS 261
           IVEALNKKE++GC+S DPD+S  LTP TEEKYKKINEEFDNM+++H I P +PP NF M 
Sbjct: 84  IVEALNKKENKGCESPDPDSSYALTPRTEEKYKKINEEFDNMIKSHKI-PAVPPPNFEMP 142

Query: 262 VTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRNVSPGAPQRPPSTG 321
           V++PV S N+L Y+NP SSL +P+L           L+ P ++   ++SPG   RPPS G
Sbjct: 143 VSIPVSSHNSLVYSNPVSSLGNPNLL---------PLAHP-SLQRNSMSPGVTHRPPSAG 192

Query: 322 NAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGSN 381
           N GG++G  DLT  +G G+S  GN + N R SP L+ + G  +L K M  KSPPP    N
Sbjct: 193 NTGGLMG-GDLT--SGAGTS-AGNGYGNPRNSPGLLVSPG--NLNKNMQAKSPPP---MN 243

Query: 382 LGMNSGKPDLRVVIPASSKGMTPPLELKSERKRESSILST 421
           LGMN+ KPDLRV+IP  SK   P +  +    + +  L+T
Sbjct: 244 LGMNNRKPDLRVLIPPGSKNTMPSVNQRINNSQSAQSLAT 283


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score =  172 bits (435), Expect = 7e-43
 Identities = 103/207 (49%), Positives = 129/207 (62%), Gaps = 11/207 (5%)

Query: 200 AYIVEALNKKEHRGCDSSDPD--TSCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQN 257
           A I+E L KK   GCDS +PD   S   +P  E+KY++ +EE D + + +     +P  N
Sbjct: 82  ADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGST--VPAPN 139

Query: 258 FSMSVTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRN-VSPGAPQR 316
           F+M VTVPV + ++L ++NP  SLV+PSL  SS LTD   LSP Q  L RN VSPG PQR
Sbjct: 140 FAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLLSPQQPALQRNSVSPGLPQR 198

Query: 317 PPSTGNAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPP 376
           P S   AG MLG  DL   NG   SPVGN +V++RASP L+     NSL KV+P KSPPP
Sbjct: 199 PAS---AGAMLGG-DLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPP 254

Query: 377 PGGS-NLGMNSGKPDLRVVIPASSKGM 402
           P  S  LG  S KPDLRV+   + KG+
Sbjct: 255 PTHSTQLGAPSRKPDLRVITSQAGKGL 281


>gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]
          Length = 473

 Score =  149 bits (377), Expect = 4e-36
 Identities = 95/205 (46%), Positives = 124/205 (60%), Gaps = 22/205 (10%)

Query: 202 IVEALNKKEHRGCDSSDPDT--SCVLTPYTEEKYKKINEEFDNMMQNHNIAPGLPPQNFS 259
           IVE L KK   GCDS DPD   S   +P +E+KY+KINE+ D M+    +   +PP NF 
Sbjct: 84  IVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLC-AVPPPNFE 142

Query: 260 MSVTVPVKSPNALSYTNPGSSLVSPSLAASSTLTDLNTLSPPQTILHRNVSPGAPQRPPS 319
           M V++PV S N+L Y+NP SSL +P+L           L+ P ++   ++SPG   RPPS
Sbjct: 143 MPVSIPVSSHNSLVYSNPVSSLGNPNLL---------PLAHP-SLQRNSMSPGVTHRPPS 192

Query: 320 TGNAGGMLGTTDLTVPNGTGSSPVGNEFVNSRASPNLIGATGANSLGKVMPTKSPPPPGG 379
            GN GG++G  DLT  +G G+S  GN + N R SP L+ + G  +L K M  KSPPP   
Sbjct: 193 AGNTGGLMG-GDLT--SGAGTS-AGNGYGNPRNSPGLLVSPG--NLNKNMQAKSPPP--- 243

Query: 380 SNLGMNSGKPDLRVVIPASSKGMTP 404
            NLGMN+ KPDLRV+IP  SK   P
Sbjct: 244 MNLGMNNRKPDLRVLIPPGSKNTMP 268


>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
           [Homo sapiens]
          Length = 320

 Score =  149 bits (377), Expect = 4e-36
 Identities = 80/131 (61%), Positives = 86/131 (65%), Gaps = 24/131 (18%)

Query: 46  GRGDGYNG---FGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGG 102
           GRG G+ G   FG  G + G G G+ GGSRG    G GYG  G GY G G+         
Sbjct: 205 GRGGGFGGNDNFGRGGNFSGRG-GF-GGSRG----GGGYGGSGDGYNGFGN--------- 249

Query: 103 GSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQG 162
                  GS+FGG GSYNDFGNYNNQSSNFGP KGGNFGGRSS P GGGGQYF KP+NQG
Sbjct: 250 ------DGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQG 303

Query: 163 GYGGSSSSRHY 173
           GYGGSSSS  Y
Sbjct: 304 GYGGSSSSSSY 314



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 15/19 (78%), Positives = 18/19 (94%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S SESPKEP+QLRKLF+G
Sbjct: 1  MSKSESPKEPEQLRKLFIG 19


>gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score =  147 bits (371), Expect = 2e-35
 Identities = 80/131 (61%), Positives = 85/131 (64%), Gaps = 24/131 (18%)

Query: 46  GRGDGYNG---FGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGG 102
           GRGDG+ G   FG  G + G G G+ GGS G    G GYG  G GY G G+         
Sbjct: 205 GRGDGFGGNDNFGRGGNFSGRG-GF-GGSCG----GGGYGGSGDGYNGFGN--------- 249

Query: 103 GSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQG 162
                  GS+FGG GSYNDFGNYNNQSSNFGP KGGNFGGRSS P GGGGQYF KPQNQG
Sbjct: 250 ------DGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPQNQG 303

Query: 163 GYGGSSSSRHY 173
           GYG SSSS  Y
Sbjct: 304 GYGVSSSSSSY 314



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 14/19 (73%), Positives = 17/19 (89%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S S SPKEP+QLRKLF+G
Sbjct: 1  MSKSASPKEPEQLRKLFIG 19


>gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score =  147 bits (371), Expect = 2e-35
 Identities = 80/131 (61%), Positives = 85/131 (64%), Gaps = 24/131 (18%)

Query: 46  GRGDGYNG---FGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGG 102
           GRGDG+ G   FG  G + G G G+ GGS G    G GYG  G GY G G+         
Sbjct: 205 GRGDGFGGNDNFGRGGNFSGRG-GF-GGSCG----GGGYGGSGDGYNGFGN--------- 249

Query: 103 GSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQG 162
                  GS+FGG GSYNDFGNYNNQSSNFGP KGGNFGGRSS P GGGGQYF KPQNQG
Sbjct: 250 ------DGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPQNQG 303

Query: 163 GYGGSSSSRHY 173
           GYG SSSS  Y
Sbjct: 304 GYGVSSSSSSY 314



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 14/19 (73%), Positives = 17/19 (89%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S S SPKEP+QLRKLF+G
Sbjct: 1  MSKSASPKEPEQLRKLFIG 19


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score =  138 bits (347), Expect = 1e-32
 Identities = 74/123 (60%), Positives = 84/123 (68%), Gaps = 12/123 (9%)

Query: 46  GRGDG-YNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGS 104
           G GDG YNGFG DGG  GGGPGYS    GYG  G GYG+QG GYGG G Y+ YN GG  +
Sbjct: 261 GGGDGGYNGFGGDGGNYGGGPGYSSRG-GYGGGGPGYGNQGGGYGGGGGYDGYNEGG--N 317

Query: 105 FGGGSGSSFGGSGSYNDFGNYN-NQSSNFGPTKGGNFGGRSS-VPCGGGGQYFVKPQNQG 162
           FGGG+   +GG G+YNDFGNY+  Q SN+GP KGG+FGGRSS  P GGG   +      G
Sbjct: 318 FGGGN---YGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGG---YGSGGGSG 371

Query: 163 GYG 165
           GYG
Sbjct: 372 GYG 374



 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 11/112 (9%)

Query: 68  SGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNN 127
           +G  RG G     +  +G  +GG G     N G GG+FGG  G   GG GS   +G  + 
Sbjct: 210 AGSQRGRGGGSGNFMGRGGNFGGGGG----NFGRGGNFGGRGGYGGGGGGSRGSYGGGDG 265

Query: 128 QSSNFGPTKGGNFGG----RSSVPCGGGGQYFVKPQNQGGYGGSSSSRHYQD 175
             + FG   GGN+GG     S    GGGG  +      GGYGG      Y +
Sbjct: 266 GYNGFG-GDGGNYGGGPGYSSRGGYGGGGPGY--GNQGGGYGGGGGYDGYNE 314


>gi|169203146 PREDICTED: similar to heterogeneous nuclear
           ribonucleoprotein A1-like [Homo sapiens]
          Length = 321

 Score =  132 bits (333), Expect = 5e-31
 Identities = 71/124 (57%), Positives = 78/124 (62%), Gaps = 13/124 (10%)

Query: 52  NGFGNDGGYGGGGPGYSGGSR-GYGSVGQGYGSQGSGYGGSGS-YNSYNNGGGGSFGGGS 109
           +G GN GG  G G G+SG    G+G    G G  G  +GGS   YN + N          
Sbjct: 197 SGSGNFGG--GRGGGFSGNDNFGHGGNFSGCGGLGGSHGGSADGYNGFGN---------D 245

Query: 110 GSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSS 169
           G +FGG  SYNDFGN NNQSSNFGP KGGNFGG+ S   GGGGQYF KPQNQGGYGGSSS
Sbjct: 246 GKNFGGGSSYNDFGNCNNQSSNFGPMKGGNFGGKRSCLYGGGGQYFAKPQNQGGYGGSSS 305

Query: 170 SRHY 173
           S  Y
Sbjct: 306 SSSY 309



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGY------SGGSRGYGSV--GQGYGSQGSGYGGSGSYNSY 97
           G  DGYNGFGNDG   GGG  Y      +  S  +G +  G   G +   YGG G Y + 
Sbjct: 234 GSADGYNGFGNDGKNFGGGSSYNDFGNCNNQSSNFGPMKGGNFGGKRSCLYGGGGQYFAK 293

Query: 98  NNGGGGSFGGGSGSSFGGSGSYNDFGN 124
               GG +GG S SS  GSG     GN
Sbjct: 294 PQNQGG-YGGSSSSSSYGSGRRFQLGN 319



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 16/19 (84%), Positives = 18/19 (94%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S SESPKEPKQLRKLF+G
Sbjct: 1  MSKSESPKEPKQLRKLFIG 19


>gi|89035135 PREDICTED: similar to heterogeneous nuclear
           ribonucleoprotein A1-like [Homo sapiens]
          Length = 321

 Score =  132 bits (332), Expect = 6e-31
 Identities = 71/124 (57%), Positives = 78/124 (62%), Gaps = 13/124 (10%)

Query: 52  NGFGNDGGYGGGGPGYSGGSR-GYGSVGQGYGSQGSGYGGSGS-YNSYNNGGGGSFGGGS 109
           +G GN GG  G G G+SG    G+G    G G  G  +GGS   YN + N          
Sbjct: 197 SGSGNFGG--GRGGGFSGNDNFGHGGNFSGCGGFGGSHGGSADGYNGFGN---------D 245

Query: 110 GSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSS 169
           G +FGG  SYNDFGN NNQSSNFGP KGGNFGG+ S   GGGGQYF KPQNQGGYGGSSS
Sbjct: 246 GKNFGGGSSYNDFGNCNNQSSNFGPMKGGNFGGKRSCLYGGGGQYFAKPQNQGGYGGSSS 305

Query: 170 SRHY 173
           S  Y
Sbjct: 306 SSSY 309



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGY------SGGSRGYGSV--GQGYGSQGSGYGGSGSYNSY 97
           G  DGYNGFGNDG   GGG  Y      +  S  +G +  G   G +   YGG G Y + 
Sbjct: 234 GSADGYNGFGNDGKNFGGGSSYNDFGNCNNQSSNFGPMKGGNFGGKRSCLYGGGGQYFAK 293

Query: 98  NNGGGGSFGGGSGSSFGGSGSYNDFGN 124
               GG +GG S SS  GSG     GN
Sbjct: 294 PQNQGG-YGGSSSSSSYGSGRRFQLGN 319



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 16/19 (84%), Positives = 18/19 (94%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S SESPKEPKQLRKLF+G
Sbjct: 1  MSKSESPKEPKQLRKLFIG 19


>gi|89034333 PREDICTED: similar to heterogeneous nuclear
           ribonucleoprotein A1-like [Homo sapiens]
          Length = 321

 Score =  132 bits (332), Expect = 6e-31
 Identities = 71/124 (57%), Positives = 78/124 (62%), Gaps = 13/124 (10%)

Query: 52  NGFGNDGGYGGGGPGYSGGSR-GYGSVGQGYGSQGSGYGGSGS-YNSYNNGGGGSFGGGS 109
           +G GN GG  G G G+SG    G+G    G G  G  +GGS   YN + N          
Sbjct: 197 SGSGNFGG--GRGGGFSGNDNFGHGGNFSGCGGFGGSHGGSADGYNGFGN---------D 245

Query: 110 GSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSS 169
           G +FGG  SYNDFGN NNQSSNFGP KGGNFGG+ S   GGGGQYF KPQNQGGYGGSSS
Sbjct: 246 GKNFGGGSSYNDFGNCNNQSSNFGPMKGGNFGGKRSCLYGGGGQYFAKPQNQGGYGGSSS 305

Query: 170 SRHY 173
           S  Y
Sbjct: 306 SSSY 309



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGY------SGGSRGYGSV--GQGYGSQGSGYGGSGSYNSY 97
           G  DGYNGFGNDG   GGG  Y      +  S  +G +  G   G +   YGG G Y + 
Sbjct: 234 GSADGYNGFGNDGKNFGGGSSYNDFGNCNNQSSNFGPMKGGNFGGKRSCLYGGGGQYFAK 293

Query: 98  NNGGGGSFGGGSGSSFGGSGSYNDFGN 124
               GG +GG S SS  GSG     GN
Sbjct: 294 PQNQGG-YGGSSSSSSYGSGRRFQLGN 319



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 16/19 (84%), Positives = 18/19 (94%)

Query: 28 LSNSESPKEPKQLRKLFLG 46
          +S SESPKEPKQLRKLF+G
Sbjct: 1  MSKSESPKEPKQLRKLFIG 19


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score =  126 bits (316), Expect = 4e-29
 Identities = 67/127 (52%), Positives = 76/127 (59%), Gaps = 18/127 (14%)

Query: 46  GRGDGYNGFGNDGGYG--GGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGG 103
           G GDGYNG+G   G G  GG PGY GG  GYG  G GYG+QG GYGG      Y+N GGG
Sbjct: 239 GFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGG-----YDNYGGG 293

Query: 104 SFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSV--PCGGGGQYFVKPQNQ 161
           ++G         SG+YNDFGNYN Q SN+GP K GNFGG  ++  P GGG          
Sbjct: 294 NYG---------SGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGS 344

Query: 162 GGYGGSS 168
           GGYGG S
Sbjct: 345 GGYGGRS 351


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score =  126 bits (316), Expect = 4e-29
 Identities = 67/127 (52%), Positives = 76/127 (59%), Gaps = 18/127 (14%)

Query: 46  GRGDGYNGFGNDGGYG--GGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGG 103
           G GDGYNG+G   G G  GG PGY GG  GYG  G GYG+QG GYGG      Y+N GGG
Sbjct: 227 GFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGG-----YDNYGGG 281

Query: 104 SFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSV--PCGGGGQYFVKPQNQ 161
           ++G         SG+YNDFGNYN Q SN+GP K GNFGG  ++  P GGG          
Sbjct: 282 NYG---------SGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGS 332

Query: 162 GGYGGSS 168
           GGYGG S
Sbjct: 333 GGYGGRS 339


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 55/139 (39%), Positives = 63/139 (45%), Gaps = 21/139 (15%)

Query: 46  GRGDGYNGFGNDGGYGGG-------GPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYN 98
           G G  Y G G+ GGYGGG       G  Y GGS   G  G GYG    G    GS   ++
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551

Query: 99  NGGGGSFGGGSGSS-------FGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGG 151
            G GG++GGGSGS         GGSGS    G  +   S FG   GG++GG       GG
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG 611

Query: 152 GQYFVKPQNQGGYGGSSSS 170
           G         GG G SS S
Sbjct: 612 GY-------GGGSGKSSHS 623



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 50/119 (42%), Positives = 56/119 (47%), Gaps = 8/119 (6%)

Query: 50  GYNGFGNDGG-YGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGG 108
           G  G G  GG YG G  G SGGS G G  G GYG      GGSG      +G GG  GGG
Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGG 533

Query: 109 SGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGS 167
            G   GG  S    G ++  S       GGN+GG S    G GG Y     ++GG GGS
Sbjct: 534 YGGGSGGGHSGGSGGGHSGGS-------GGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS 585



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 55/129 (42%), Positives = 61/129 (47%), Gaps = 18/129 (13%)

Query: 48  GDGYNGFGNDGGYGGGGPG--YSGGSRGYGSVGQGYGSQGSGYG-GSGSYNSYNNGGGGS 104
           G G  G G+ G YGGGG G  Y GGS   GS G   GS G G G G GS   Y  G GG 
Sbjct: 486 GRGSRG-GSGGSYGGGGSGGGYGGGS---GSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG 541

Query: 105 FGGGSGSSF-GGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGG 163
             GGSG    GGSG     GNY   S + G   GG +GG S    G GG +        G
Sbjct: 542 HSGGSGGGHSGGSG-----GNYGGGSGS-GGGSGGGYGGGSGSRGGSGGSH----GGGSG 591

Query: 164 YGGSSSSRH 172
           +GG S   +
Sbjct: 592 FGGESGGSY 600



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 43/105 (40%), Positives = 50/105 (47%), Gaps = 27/105 (25%)

Query: 46  GRGDGYN-GFGNDGGYGGG------GPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNS-Y 97
           GRG G + G+   GG GGG      G G+ GGSRG+G      G+ G GY  SG +   +
Sbjct: 62  GRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFG------GASGGGYSSSGGFGGGF 115

Query: 98  NNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGG 142
             G GG FGGG GS FGG G              FG   GG  GG
Sbjct: 116 GGGSGGGFGGGYGSGFGGFG-------------GFGGGAGGGDGG 147



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 54/143 (37%), Positives = 61/143 (42%), Gaps = 17/143 (11%)

Query: 38  KQLRKLFLGRGDGYNGFGNDGGYGGGGP---GYSGGSRGYGSVGQGYGSQGSGYGGSGSY 94
           +Q    +L R  G    G  GG G GG     YS  S   G  G G  S  SGYGG GS 
Sbjct: 4   RQFSSSYLSRSGG----GGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGG-GSS 58

Query: 95  NSYNNGGGGSF----GGGSGSSFGGSGSYNDFGNYN---NQSSNFGPTKGGNFGGRSSVP 147
                GGGGSF    GGGSG  F  S     FG  +     +S  G +  G FGG     
Sbjct: 59  RVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGG 118

Query: 148 CGG--GGQYFVKPQNQGGYGGSS 168
            GG  GG Y       GG+GG +
Sbjct: 119 SGGGFGGGYGSGFGGFGGFGGGA 141



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 48/127 (37%), Positives = 56/127 (44%), Gaps = 26/127 (20%)

Query: 51  YNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYN-SYNNGGGGSFG--- 106
           Y+ F + GG GGGG   S  S GYG    G  S+  G GG GS+  SY  G GG F    
Sbjct: 32  YSRFSSSGGGGGGGRFSS--SSGYG----GGSSRVCGRGGGGSFGYSYGGGSGGGFSASS 85

Query: 107 -----GGSGSSFGGS--GSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQ 159
                GG    FGG+  G Y+  G +      FG   GG FGG      GG G +     
Sbjct: 86  LGGGFGGGSRGFGGASGGGYSSSGGF---GGGFGGGSGGGFGGGYGSGFGGFGGF----- 137

Query: 160 NQGGYGG 166
             GG GG
Sbjct: 138 -GGGAGG 143



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 11/109 (10%)

Query: 69  GGSRGYGSVGQGYGSQGSGYGG----SGSYNSYNNGG-GGSF-GGGSGSSF-GGSGSYND 121
           GG   + S G G      G GG     GSY   + GG GGS+ GGGSG  + GGSGS   
Sbjct: 460 GGQEDFESSGAGK----IGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515

Query: 122 FGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSS 170
            G      S  G   GG +GG S     GG        + G YGG S S
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGS 564



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 21/81 (25%)

Query: 46  GRGDGYNGFG--NDGGY---GGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNG 100
           G G G  GFG  + GGY   GG G G+ GGS G    G GYGS   G+GG          
Sbjct: 89  GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG--GFGGGYGSGFGGFGG---------- 136

Query: 101 GGGSFGGGSGSSFGGSGSYND 121
               FGGG+G   GG  + N+
Sbjct: 137 ----FGGGAGGGDGGILTANE 153



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/87 (41%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 91  SGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNF------GGRS 144
           S SY S + GGGG  G GSG S   S        Y+  SS+ G   GG F      GG S
Sbjct: 7   SSSYLSRSGGGGGG-GLGSGGSIRSS--------YSRFSSSGGGGGGGRFSSSSGYGGGS 57

Query: 145 SVPCG-GGGQYFVKPQNQGGYGGSSSS 170
           S  CG GGG  F      G  GG S+S
Sbjct: 58  SRVCGRGGGGSFGYSYGGGSGGGFSAS 84


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 53/123 (43%), Positives = 60/123 (48%), Gaps = 13/123 (10%)

Query: 59  GYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNN---GGGGSF----GGGSGS 111
           G GGGG   S G RG    G G    G   GG G YNSY     GGGG +    GGG GS
Sbjct: 182 GGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGS 241

Query: 112 SFGGS---GSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGG---GGQYFVKPQNQGGYG 165
           S+GGS     +  FG+Y+   S++GP K G  GG      GG    G Y       GGYG
Sbjct: 242 SYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYG 301

Query: 166 GSS 168
           GSS
Sbjct: 302 GSS 304



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 37/111 (33%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 86  SGYGGSGSYNSYNNGGGGSFGGG---SGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGG 142
           SG GG GS +S    GG   GGG   +G S GG G YN +G Y           GG  GG
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYG----------GGGGGG 230

Query: 143 RSSVPCGGGGQYFVKPQNQGGYGGSSSSRHYQDVLASPKLKEAAPGSAERW 193
            ++   GGGG  +       G+GG  S   +Q      K      G    W
Sbjct: 231 YNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSW 281


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 60/126 (47%), Positives = 69/126 (54%), Gaps = 20/126 (15%)

Query: 48  GDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGS--GSYNSYNNGGGGSF 105
           G+G +G G  GG G  G GY GGS G GS G G+G    G+GGS  G Y   ++GGG S 
Sbjct: 455 GEGSSGGGGRGG-GSFGGGYGGGSSGGGSSGGGHGG---GHGGSSGGGYGGGSSGGGSSG 510

Query: 106 GG-GSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGY 164
           GG G GSS GG G  +  G Y   SS  G   GG +GG SS   GGG        + GGY
Sbjct: 511 GGYGGGSSSGGHGG-SSSGGYGGGSSGGG---GGGYGGGSS---GGGS------SSGGGY 557

Query: 165 GGSSSS 170
           GG SSS
Sbjct: 558 GGGSSS 563



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 16/124 (12%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSF 105
           G G G +G G+ GG  GGG G S G  GYG    G GS G GYGG  S   +   GG S 
Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGSSGG-GYGGGSSGGGSSGGGYGGGSSSGGH---GGSSS 527

Query: 106 GGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYG 165
           GG  G S GG G     G Y   SS  G + GG +GG SS     GG    K  + G  G
Sbjct: 528 GGYGGGSSGGGG-----GGYGGGSSGGGSSSGGGYGGGSS----SGGH---KSSSSGSVG 575

Query: 166 GSSS 169
            SSS
Sbjct: 576 ESSS 579



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 65/216 (30%), Positives = 87/216 (40%), Gaps = 35/216 (16%)

Query: 46  GRGDGYNGFGNDGGYG-----------GGG---PGYSGGSRGYGSVGQG-YGSQGSGYGG 90
           G G G  G G  GG             GGG    G+SGGS   GS G G +G    GYGG
Sbjct: 17  GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76

Query: 91  SGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGG 150
            G +      GGGSF G  GSS  G GSY   G++   S   G   GG+FGG      G 
Sbjct: 77  LGGF------GGGSFRGSYGSSSFG-GSYG--GSFGGGSFGGGSFGGGSFGGGGFGGGGF 127

Query: 151 GGQYFVKPQNQGGYGGSSSSRHYQDVLASPKLKEAAPGSAERWRRAQAAAYIVEALNKKE 210
           GG +       GG+GG        + +    L +      ++ R  + + Y +E   K+ 
Sbjct: 128 GGGF------GGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEW 181

Query: 211 HRGCDSSDPDTSCVLTPYTEEKYKKINEEFDNMMQN 246
           +    +S         P    KY K  ++  N + N
Sbjct: 182 YEKHGNSHQG-----EPRDYSKYYKTIDDLKNQILN 212



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 49/119 (41%), Positives = 60/119 (50%), Gaps = 14/119 (11%)

Query: 52  NGFGNDGGYGGGGPGYSG--GSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGS 109
           +G G  GG  GGG G S    S   GS+G G+ S G     SG   S  + GGG FGG S
Sbjct: 16  SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGF----SGGSFSRGSSGGGCFGGSS 71

Query: 110 G--SSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGG 166
           G     GG G  +  G+Y   SS+FG + GG+FGG S     GGG +       GG+GG
Sbjct: 72  GGYGGLGGFGGGSFRGSYG--SSSFGGSYGGSFGGGSF----GGGSFGGGSFGGGGFGG 124



 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 40/96 (41%), Positives = 46/96 (47%), Gaps = 9/96 (9%)

Query: 74  YGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFG 133
           Y S+ +G GS G G  G GS+     GGG S GG SG   GG    +  G Y   SS  G
Sbjct: 449 YRSLLEGEGSSGGGGRGGGSFGG-GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507

Query: 134 PTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSS 169
            + GG  GG SS   GG         + GGYGG SS
Sbjct: 508 SSGGGYGGGSSSGGHGG--------SSSGGYGGGSS 535



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 34/80 (42%), Positives = 37/80 (46%), Gaps = 12/80 (15%)

Query: 48  GDGYNGFGNDGGYGGGGPG-YSGGSRGYGSVGQGYGSQGSG---YGGSGSYNSYNNGGGG 103
           G GY G  + GG+GG   G Y GGS G G  G G GS G G    GG         GGG 
Sbjct: 510 GGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG--------YGGGS 561

Query: 104 SFGGGSGSSFGGSGSYNDFG 123
           S GG   SS G  G  +  G
Sbjct: 562 SSGGHKSSSSGSVGESSSKG 581



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 46/127 (36%), Positives = 55/127 (43%), Gaps = 30/127 (23%)

Query: 51  YNGFGNDGGYGGGGPGYSGG------SRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGS 104
           Y+   + GG GGGG G  GG      S   GS+G G+ S G   GGS S  S    GGG 
Sbjct: 11  YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS-GGSFSRGS---SGGGC 66

Query: 105 FGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNF-GGRSSVPCGG--GGQYFVKPQNQ 161
           FGG SG  +GG G +                 GG+F G   S   GG  GG +       
Sbjct: 67  FGGSSGG-YGGLGGFG----------------GGSFRGSYGSSSFGGSYGGSFGGGSFGG 109

Query: 162 GGYGGSS 168
           G +GG S
Sbjct: 110 GSFGGGS 116



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 32/81 (39%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 93  SYNSYNNGGGGSFGGG-SGSSFG---GSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPC 148
           +Y S   G G S GGG  G SFG   G GS     +        G + GG +GG SS   
Sbjct: 448 TYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507

Query: 149 GGGGQYFVKPQNQGGYGGSSS 169
             GG Y     + GG+GGSSS
Sbjct: 508 SSGGGY-GGGSSSGGHGGSSS 527



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 14/104 (13%)

Query: 71  SRGYGSVGQGYGSQGSGYGGSGSYNSYN-NGGGGSFGGGSGSSFGGSGSYNDFGNYNNQS 129
           S+ Y S   G G  G G GG G  +S   +   GS GGG  S           G ++  S
Sbjct: 8   SKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSS-----------GGFSGGS 56

Query: 130 SNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSSRHY 173
            + G + GG FGG S    G GG  F     +G YG SS    Y
Sbjct: 57  FSRGSSGGGCFGGSSGGYGGLGG--FGGGSFRGSYGSSSFGGSY 98


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 55/131 (41%), Positives = 64/131 (48%), Gaps = 6/131 (4%)

Query: 44  FLGRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGG 103
           F G G G    G+  GY GGG GYSGG  G GS G G G    G GG    +   +GGGG
Sbjct: 37  FGGGGSGGGSSGSGCGYSGGG-GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGG 95

Query: 104 SFGGGSG---SSFGGSGSYND--FGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKP 158
           S GGGSG   S  GGSG ++    G+    S  F    GG+ GG S     GGG +  + 
Sbjct: 96  SSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQA 155

Query: 159 QNQGGYGGSSS 169
                YGG SS
Sbjct: 156 VQCQSYGGVSS 166



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 53/132 (40%), Positives = 62/132 (46%), Gaps = 9/132 (6%)

Query: 46  GRGDGYNGFGNDGG----YGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGS--GSYNSYNN 99
           G G G  G G   G    Y GGG    GGS  + S G G G   SG GGS  G    +++
Sbjct: 72  GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSS 131

Query: 100 GGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQ 159
           GGGGS GGGSG    G G ++  G      S  G + GG+ GG S     GGG   V   
Sbjct: 132 GGGGSSGGGSGCFSSGGGGFS--GQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGY 189

Query: 160 NQGGYG-GSSSS 170
           + GG G G  SS
Sbjct: 190 SGGGSGCGGGSS 201



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 50/120 (41%), Positives = 56/120 (46%), Gaps = 12/120 (10%)

Query: 53  GFGNDGGYGGGGPGY-SGGSRGYGSVGQGYG-SQGSGYGGSGSYNSYNNGGGGSFGGGSG 110
           G G  GG GGGG G+  GG  G GS G G G S G GY G G     + GGGG   GG G
Sbjct: 22  GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81

Query: 111 SSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSS 170
              GGS  Y+  G  +   S    + GG  G  SS   GGGG       + GG  G  SS
Sbjct: 82  GGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS---GGGG-------SSGGGSGCFSS 131



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 45/113 (39%), Positives = 50/113 (44%), Gaps = 10/113 (8%)

Query: 59  GYGGGGPGYSGGSRG-YGSVGQGYGSQGSGYGGSGSYNSYNNG--GGGSFGGGSGSSFGG 115
           G GGGG G  GG  G +G  G G GS GSG G SG    Y+ G  GGGS GGG G   GG
Sbjct: 21  GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGG-GGYSGGGCGGGSSGGGGGGGIGG 79

Query: 116 SGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSS 168
                  G  +  S  +    G + GG      GGGG         G  GG S
Sbjct: 80  C------GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGS 126



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 50/137 (36%), Positives = 58/137 (42%), Gaps = 22/137 (16%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSG-----------SY 94
           G   G +G  + GG GG   GYSGG  G G  G   G  GSGY  S            SY
Sbjct: 168 GSSGGGSGCFSSGGGGGSVCGYSGGGSGCG--GGSSGGSGSGYVSSQQVTQTSCAPQPSY 225

Query: 95  NSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQY 154
              ++GGGGS G G  SS GG GS    G  +   S    + GG+  G  S   GGGG  
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGG-- 283

Query: 155 FVKPQNQGGYGGSSSSR 171
                     GGS S +
Sbjct: 284 -------SSVGGSGSGK 293



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 47/134 (35%), Positives = 55/134 (41%), Gaps = 20/134 (14%)

Query: 48  GDGYNGFGNDGGYGGGGPGYSGGS---RGYGSVGQGYGSQGSGYG------GSGSYNSYN 98
           G G +  G  G +  GG G+SG +   + YG V  G GS G G G      G GS   Y+
Sbjct: 132 GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSG-GSSGGGSGCFSSGGGGGSVCGYS 190

Query: 99  NGG---GGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYF 155
            GG   GG   GGSGS +  S            S   G + GG  GG      GGGG   
Sbjct: 191 GGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGG--- 247

Query: 156 VKPQNQGGYGGSSS 169
                  G GG SS
Sbjct: 248 ----GSSGCGGGSS 257



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 50/142 (35%), Positives = 61/142 (42%), Gaps = 22/142 (15%)

Query: 44  FLGRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQ-------------GSGYGG 90
           F   G G +G G+     GGG    GGS  + S G G+  Q             GS  GG
Sbjct: 114 FSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG 173

Query: 91  SGSYNSYNNGGGGSF----GGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSV 146
           SG ++S   GGGGS     GGGSG   G SG        + Q +        ++GG SS 
Sbjct: 174 SGCFSS--GGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSS- 230

Query: 147 PCGGGGQYFVKPQNQGGYGGSS 168
             GGGG       + GG GGSS
Sbjct: 231 --GGGGSGGSGCFSSGGGGGSS 250



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 37/90 (41%), Positives = 41/90 (45%), Gaps = 10/90 (11%)

Query: 83  SQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGS---YNDFGNYNNQSSNFGPTKGGN 139
           + G G GG GS      GG G FGGG GS  G SGS   Y+  G Y+      G + GG 
Sbjct: 19  TSGGGGGGGGS----GGGGCGFFGGG-GSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGG 73

Query: 140 FGGRSSVPCGGGGQYFVKPQNQGGYGGSSS 169
            GG     CGGG    VK    GG  G  S
Sbjct: 74  GGGIGG--CGGGSGGSVKYSGGGGSSGGGS 101



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 33/69 (47%), Positives = 34/69 (49%), Gaps = 7/69 (10%)

Query: 53  GFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYG----GSGSY---NSYNNGGGGSF 105
           G G+ GG G GG G      G GS G G GS G G G    G GS     S   GGGGS 
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSS 285

Query: 106 GGGSGSSFG 114
            GGSGS  G
Sbjct: 286 VGGSGSGKG 294



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 19/44 (43%), Positives = 21/44 (47%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYG 89
           G G G +G G+     GGG    GGS G G  G   G  GSG G
Sbjct: 251 GCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 14/160 (8%)

Query: 19  IKVSLLPAVLSNSESPKEPKQLRKLFLGRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVG 78
           ++++    +L   ES    +    + +     +      G  GGGG GY  G   YGS G
Sbjct: 477 LEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGG 536

Query: 79  QGYGSQGSGYGGSGSYNSYNNG------GGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNF 132
              GS GSG GG G   SY +G      GGGS+G G G   GG GSY    +        
Sbjct: 537 ---GSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGG--GGHGSYGSGSSSGGYRGGS 591

Query: 133 GPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGY---GGSSS 169
           G   GG+ GGR S     GG    +  + GG    GGSSS
Sbjct: 592 GGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSS 631



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 48/111 (43%), Positives = 57/111 (51%), Gaps = 12/111 (10%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGY---GGSGSYNSYNNGG- 101
           G G G + +G+ GG  G G G  GG   YGS G  YGS G  Y   GG G + SY +G  
Sbjct: 524 GYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSS 583

Query: 102 -----GGSFGGGSGSSFG-GSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSV 146
                GGS GGG GSS G GSG  +  G+   + S+ G  K    GG SSV
Sbjct: 584 SGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSS--GGSSSV 632



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 51/138 (36%), Positives = 58/138 (42%), Gaps = 28/138 (20%)

Query: 52  NGFGNDGGYGGGGPGY--------------SGGSRG-YGSVGQGYGSQGSGYGGSGSYNS 96
           +G+ + GG+  G  G               SGG  G + S G G GS G+G GG GS + 
Sbjct: 9   SGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAG-GGFGSRSL 67

Query: 97  YNNGGGGSF------GGGSGSSFGGSGSYNDFGNYNNQSSNFGP--TKGGNFGGRSSVPC 148
            N GG  S       GGG GS FGG      FG        FG     GG FGG  S   
Sbjct: 68  VNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGG 127

Query: 149 GGGGQYFVKPQNQGGYGG 166
           G GG  F      GGYGG
Sbjct: 128 GFGGGGF----GGGGYGG 141



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 45/105 (42%), Positives = 52/105 (49%), Gaps = 19/105 (18%)

Query: 69  GGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFG-NYNN 127
           GGSRG G  G GYGS GS YG           GGGS+G G G   GG GSY   G +Y +
Sbjct: 515 GGSRGGG--GGGYGSGGSSYGS----------GGGSYGSGGGGG-GGRGSYGSGGSSYGS 561

Query: 128 QSSNFGPTKGGNFGGRSSVPCG-GGGQYFVKPQNQGGYGGSSSSR 171
              ++G   GG  GG  S   G   G Y  +  + GG GGSS  R
Sbjct: 562 GGGSYG--SGGGGGGHGSYGSGSSSGGY--RGGSGGGGGGSSGGR 602



 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 51/141 (36%), Positives = 60/141 (42%), Gaps = 27/141 (19%)

Query: 44  FLGRGDGYNGFGNDGGYGGGGPGYSGGSRGYG-SVGQGYGSQGSGYGGSGSYNSYNNGGG 102
           F   G G   FG  GG+G       GGS+    SV +G G +GSG+GG   Y     GGG
Sbjct: 46  FSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARG-GGRGSGFGGG--YGGGGFGGG 102

Query: 103 GSFGGG-SGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQ 161
           G  GGG  G   GG G    FG + +    FG   GG FGG      GG G         
Sbjct: 103 GFGGGGFGGGGIGGGG----FGGFGSGGGGFG---GGGFGG------GGYG--------- 140

Query: 162 GGYGGSSSSRHYQDVLASPKL 182
           GGYG        Q+V  +  L
Sbjct: 141 GGYGPVCPPGGIQEVTINQSL 161



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/71 (39%), Positives = 33/71 (46%), Gaps = 9/71 (12%)

Query: 46  GRGDGYNGFGN---DGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGG 102
           G G G+  +G+    GGY GG  G  GGS G      G GS G   GGS      ++GG 
Sbjct: 570 GGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG------GRGSGGGSSGGSIGGRGSSSGGV 623

Query: 103 GSFGGGSGSSF 113
            S GG S   F
Sbjct: 624 KSSGGSSSVKF 634


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 56/132 (42%), Positives = 61/132 (46%), Gaps = 13/132 (9%)

Query: 48  GDGYNGFGNDGGYGG--GGPGYSGGSRGYGSVGQGYGSQGSGYGG--SGSYNSYNNGGGG 103
           G GY+G  + GGYGG   G GY GG RG G  G   G +G GYGG   G Y     G GG
Sbjct: 431 GGGYSGDRSGGGYGGDRSGGGY-GGDRG-GGYG---GDRGGGYGGDRGGGYGGDRGGYGG 485

Query: 104 SFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGG--GGQYFVKPQNQ 161
             GGG G   GG G   D G Y      +G  +GG  G RS    GG  GG         
Sbjct: 486 DRGGGYGGDRGGYG--GDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS 543

Query: 162 GGYGGSSSSRHY 173
           GGYGG  S   Y
Sbjct: 544 GGYGGDRSGGGY 555



 Score = 75.9 bits (185), Expect = 7e-14
 Identities = 54/133 (40%), Positives = 63/133 (47%), Gaps = 16/133 (12%)

Query: 48  GDGYNGFGND--GGYGGG-GPGYSGGSRGYGSV-GQGYGSQGSGYGGS-GSYNSYNNGGG 102
           GD   G+G D  GGYGG  G GY G   GYG   G GYG    GYGG  G Y     G G
Sbjct: 454 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYG 513

Query: 103 GSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGG-RSSVPCGG--GGQYFVKPQ 159
           G  GG     +GG  S   +G      S +G  + G +GG RS    GG  GG Y     
Sbjct: 514 GDRGG-----YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY---GG 565

Query: 160 NQGGYGGSSSSRH 172
           ++GGYGG    R+
Sbjct: 566 DRGGYGGKMGGRN 578



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 52/156 (33%), Positives = 63/156 (40%), Gaps = 16/156 (10%)

Query: 30  NSESPKEPKQLRKLFLGRG-DGYNGFGNDGGYGGGGPGYSGGSRGYG-----SVGQGYGS 83
           N   P++ +     F GRG  G  G+   GG GG   GY G   G G     S G GY  
Sbjct: 377 NEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSG 436

Query: 84  Q--GSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFG 141
              G GYGG  S   Y    GG +GG  G  +GG       G Y      +G  +GG +G
Sbjct: 437 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG----GGYGGDRGGYGGDRGGGYG 492

Query: 142 GRSSVPCGGGGQYFVKPQ----NQGGYGGSSSSRHY 173
           G      G  G Y         ++GGYGG  S   Y
Sbjct: 493 GDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 528



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 39/87 (44%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 46  GRGDGYNGFGND-GGYGGGGPGYSGGSR---GYG---SVGQGYGSQGS-GYGGSGSYNSY 97
           G G    G+G D GGYGG   GY GG R   GYG     G GYG   S GYGG  S   Y
Sbjct: 497 GYGGDRGGYGGDRGGYGGDRGGY-GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY 555

Query: 98  NNGGGGSFGGGSGSSFGGSGSYNDFGN 124
               GG +GG  G   G  G  ND+ N
Sbjct: 556 GGDRGGGYGGDRGGYGGKMGGRNDYRN 582



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 39/102 (38%), Positives = 42/102 (41%), Gaps = 18/102 (17%)

Query: 48  GDGYNGFGND-GGYGGGGPGYSGGSRGYGSVGQGYGSQ------------GSGYGG--SG 92
           GD   G+G D GGYGG   GY G   GYG    GYG              GSGYGG  SG
Sbjct: 485 GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG 544

Query: 93  SYNSYNNGGG---GSFGGGSGSSFGGSGSYNDFGNYNNQSSN 131
            Y    +GGG      GG  G   G  G      +Y N   N
Sbjct: 545 GYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRN 586



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 45/152 (29%), Positives = 59/152 (38%), Gaps = 26/152 (17%)

Query: 46  GRGDGYNGFGNDG--GYGGGGPGYSGGSR-----------GYGSVGQGYGSQGSGYGG-- 90
           G    Y+ +GN G  GYG     YSG  +           GY S GQ Y     GY    
Sbjct: 12  GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQK 71

Query: 91  --SGSYNSYNNGGGGSFGGGSGSSFGGSGSYN--DFGNYNNQSSNFG-PTKGGNFGGRSS 145
             S S   YNN G       SGS  G + SY+  D+G  ++     G     G++  +S+
Sbjct: 72  QSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSN 131

Query: 146 VPCGGGGQYFVKPQNQGGYGG--SSSSRHYQD 175
                  Q+    QNQ  Y     + S H QD
Sbjct: 132 Y----DQQHDSYSQNQQSYHSQRENYSHHTQD 159



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/166 (28%), Positives = 54/166 (32%), Gaps = 61/166 (36%)

Query: 58  GGYGGGGPGYSGGSRGYGSVGQGYGS---------------------------------- 83
           GG  GGG    GG RG G   QG G                                   
Sbjct: 324 GGGSGGGRRGRGGYRGRGGF-QGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 382

Query: 84  ---------QGSGYGGSGSYNSYNNGGG--GSFG--------GGSGSSFGGSGSYNDFGN 124
                    +G GYGG   Y      GG  G +G        GG  SS GG       G 
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442

Query: 125 YNNQSS--NFGPTKGGNFGGRSSVPCGG--GGQYFVKPQNQGGYGG 166
           Y    S   +G  +GG +GG      GG  GG Y     ++GGYGG
Sbjct: 443 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGY---GGDRGGYGG 485



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 12/99 (12%)

Query: 56  NDGGYGGGGPGYSGGSRGYGSVG-QGYGSQGSGYGGSG----SYNSYNNGGGGSFGGGSG 110
           + G YG  G G       YG+ G QGYG     Y G G    S    N  G  S+G    
Sbjct: 3   DSGSYGQSG-GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61

Query: 111 SSFGG-----SGSYNDFGNYNNQSSNFGPTKGGNFGGRS 144
            S+GG       SY+    YNNQ         G+ GGR+
Sbjct: 62  QSYGGYENQKQSSYSQ-QPYNNQGQQQNMESSGSQGGRA 99



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 12/104 (11%)

Query: 82  GSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYND--FGNYNNQSSNFGPTKGGN 139
           GS G   G   SY++Y N G   +G  S  S+ G G   D  +G   +  S++G +   +
Sbjct: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQAS-QSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63

Query: 140 FGG--------RSSVPCGGGGQYFVKPQNQGGYGGSSSSRHYQD 175
           +GG         S  P    GQ     ++ G  GG + S    D
Sbjct: 64  YGGYENQKQSSYSQQPYNNQGQQ-QNMESSGSQGGRAPSYDQPD 106



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 8/54 (14%)

Query: 74  YGSVGQGY-GSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGG---SGSYNDFG 123
           YG   +GY GSQG G G  G    Y+  G G   G SG   GG    G + D+G
Sbjct: 167 YGEDNRGYGGSQGGGRGRGG----YDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 11/79 (13%)

Query: 104 SFGGGSGSSFGGSGSYNDFGNYNNQS--------SNFGPTKGGNFGGRSSVPCGGGGQYF 155
           S  G  G S G   SY+ +GN  +Q         S +G T   ++G   S     G  Y 
Sbjct: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSY- 60

Query: 156 VKPQNQGGYGGSSSSRHYQ 174
              Q+ GGY     S + Q
Sbjct: 61  --SQSYGGYENQKQSSYSQ 77


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 56/132 (42%), Positives = 61/132 (46%), Gaps = 13/132 (9%)

Query: 48  GDGYNGFGNDGGYGG--GGPGYSGGSRGYGSVGQGYGSQGSGYGG--SGSYNSYNNGGGG 103
           G GY+G  + GGYGG   G GY GG RG G  G   G +G GYGG   G Y     G GG
Sbjct: 434 GGGYSGDRSGGGYGGDRSGGGY-GGDRG-GGYG---GDRGGGYGGDRGGGYGGDRGGYGG 488

Query: 104 SFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGG--GGQYFVKPQNQ 161
             GGG G   GG G   D G Y      +G  +GG  G RS    GG  GG         
Sbjct: 489 DRGGGYGGDRGGYG--GDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRS 546

Query: 162 GGYGGSSSSRHY 173
           GGYGG  S   Y
Sbjct: 547 GGYGGDRSGGGY 558



 Score = 75.9 bits (185), Expect = 7e-14
 Identities = 54/133 (40%), Positives = 63/133 (47%), Gaps = 16/133 (12%)

Query: 48  GDGYNGFGND--GGYGGG-GPGYSGGSRGYGSV-GQGYGSQGSGYGGS-GSYNSYNNGGG 102
           GD   G+G D  GGYGG  G GY G   GYG   G GYG    GYGG  G Y     G G
Sbjct: 457 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYG 516

Query: 103 GSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGG-RSSVPCGG--GGQYFVKPQ 159
           G  GG     +GG  S   +G      S +G  + G +GG RS    GG  GG Y     
Sbjct: 517 GDRGG-----YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGY---GG 568

Query: 160 NQGGYGGSSSSRH 172
           ++GGYGG    R+
Sbjct: 569 DRGGYGGKMGGRN 581



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 52/156 (33%), Positives = 63/156 (40%), Gaps = 16/156 (10%)

Query: 30  NSESPKEPKQLRKLFLGRG-DGYNGFGNDGGYGGGGPGYSGGSRGYG-----SVGQGYGS 83
           N   P++ +     F GRG  G  G+   GG GG   GY G   G G     S G GY  
Sbjct: 380 NEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSG 439

Query: 84  Q--GSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFG 141
              G GYGG  S   Y    GG +GG  G  +GG       G Y      +G  +GG +G
Sbjct: 440 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG----GGYGGDRGGYGGDRGGGYG 495

Query: 142 GRSSVPCGGGGQYFVKPQ----NQGGYGGSSSSRHY 173
           G      G  G Y         ++GGYGG  S   Y
Sbjct: 496 GDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 531



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 39/87 (44%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 46  GRGDGYNGFGND-GGYGGGGPGYSGGSR---GYG---SVGQGYGSQGS-GYGGSGSYNSY 97
           G G    G+G D GGYGG   GY GG R   GYG     G GYG   S GYGG  S   Y
Sbjct: 500 GYGGDRGGYGGDRGGYGGDRGGY-GGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY 558

Query: 98  NNGGGGSFGGGSGSSFGGSGSYNDFGN 124
               GG +GG  G   G  G  ND+ N
Sbjct: 559 GGDRGGGYGGDRGGYGGKMGGRNDYRN 585



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 39/102 (38%), Positives = 42/102 (41%), Gaps = 18/102 (17%)

Query: 48  GDGYNGFGND-GGYGGGGPGYSGGSRGYGSVGQGYGSQ------------GSGYGG--SG 92
           GD   G+G D GGYGG   GY G   GYG    GYG              GSGYGG  SG
Sbjct: 488 GDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSG 547

Query: 93  SYNSYNNGGG---GSFGGGSGSSFGGSGSYNDFGNYNNQSSN 131
            Y    +GGG      GG  G   G  G      +Y N   N
Sbjct: 548 GYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRN 589



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 35/102 (34%), Positives = 42/102 (41%), Gaps = 16/102 (15%)

Query: 55  GNDGGYGGGGPGYSG----GSRGYGSVGQ---GYG-----SQGSGYGGSGSYNSYNNGGG 102
           G+ G  GG    YS     GS+GYG   Q   GYG     S G  Y G  SY    +G  
Sbjct: 5   GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64

Query: 103 GSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRS 144
            S+GG          SY+    YNNQ         G+ GGR+
Sbjct: 65  QSYGGYENQK---QSSYSQ-QPYNNQGQQQNMESSGSQGGRA 102



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/166 (28%), Positives = 54/166 (32%), Gaps = 61/166 (36%)

Query: 58  GGYGGGGPGYSGGSRGYGSVGQGYGS---------------------------------- 83
           GG  GGG    GG RG G   QG G                                   
Sbjct: 327 GGGSGGGRRGRGGYRGRGGF-QGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 385

Query: 84  ---------QGSGYGGSGSYNSYNNGGG--GSFG--------GGSGSSFGGSGSYNDFGN 124
                    +G GYGG   Y      GG  G +G        GG  SS GG       G 
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445

Query: 125 YNNQSS--NFGPTKGGNFGGRSSVPCGG--GGQYFVKPQNQGGYGG 166
           Y    S   +G  +GG +GG      GG  GG Y     ++GGYGG
Sbjct: 446 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGY---GGDRGGYGG 488



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 11/132 (8%)

Query: 51  YNGFGN--DGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGG 108
           Y+G+G   D  YG    GYS   +      Q YG   +    S S   YNN G       
Sbjct: 35  YSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMES 94

Query: 109 SGSSFGGSGSYN--DFGNYNNQSSNFG-PTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYG 165
           SGS  G + SY+  D+G  ++     G     G++  +S+       Q+    QNQ  Y 
Sbjct: 95  SGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY----DQQHDSYSQNQQSYH 150

Query: 166 G--SSSSRHYQD 175
               + S H QD
Sbjct: 151 SQRENYSHHTQD 162



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 5/116 (4%)

Query: 56  NDGGYGGGGPGYSGGSRGYGSVG-QGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFG 114
           + G YG  G G       YG+ G QGYG     Y G G   + ++  G ++ G S     
Sbjct: 3   DSGSYGQSG-GEQQSYSTYGNPGSQGYGQASQSYSGYG--QTTDSSYGQNYSGYSSYGQS 59

Query: 115 GSGSYNDFGNYNNQ-SSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSS 169
            SG    +G Y NQ  S++      N G + ++   G         +Q  YG   S
Sbjct: 60  QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 115



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 8/54 (14%)

Query: 74  YGSVGQGY-GSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGG---SGSYNDFG 123
           YG   +GY GSQG G G  G    Y+  G G   G SG   GG    G + D+G
Sbjct: 170 YGEDNRGYGGSQGGGRGRGG----YDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 22/79 (27%), Positives = 30/79 (37%), Gaps = 8/79 (10%)

Query: 104 SFGGGSGSSFGGSGSYNDFGNYNNQS--------SNFGPTKGGNFGGRSSVPCGGGGQYF 155
           S  G  G S G   SY+ +GN  +Q         S +G T   ++G   S     G    
Sbjct: 2   SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61

Query: 156 VKPQNQGGYGGSSSSRHYQ 174
              Q+ GGY     S + Q
Sbjct: 62  GYSQSYGGYENQKQSSYSQ 80


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 51/118 (43%), Positives = 64/118 (54%), Gaps = 6/118 (5%)

Query: 54  FGNDGGYGGG-GPGYSGGSRGYGSVGQGYGSQG-SGYGGSGSYNSYNNGGG--GSFGGGS 109
           FG  GG G   G GYS GS  YGS G+  GS+G SG GGS S   Y +GGG  G +G G 
Sbjct: 518 FGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGG 577

Query: 110 GSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGS 167
           G S GGS S   +G+   + S+ G ++GG+  G      GGGG   VK  +   +G S
Sbjct: 578 G-SKGGSISGGGYGSGGGKHSSGGGSRGGSSSG-GGYGSGGGGSSSVKGSSGEAFGSS 633



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 35/78 (44%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 48  GDGYNGFGNDGGYGGGGPGYSGGS---RGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGS 104
           G GY   G  GG  G G G  GGS    GYGS G  + S G   GGS S   Y +GGGGS
Sbjct: 560 GGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGS 619

Query: 105 FG--GGSGSSFGGSGSYN 120
               G SG +FG S +++
Sbjct: 620 SSVKGSSGEAFGSSVTFS 637



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 43/116 (37%), Positives = 49/116 (42%), Gaps = 19/116 (16%)

Query: 55  GNDGGYGGGGPGYSG--GSRGYGSVGQGYGSQGSGYGGSGSYNSYNN--GGGGSFGGGSG 110
           G  GG+GGGG G     G  G  S+       G G+G +G +       GGG SFGGGSG
Sbjct: 48  GGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSG 107

Query: 111 SSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGG 166
            S GG G              FG  + G FGG   V   GG   F      GGY G
Sbjct: 108 FSGGGFG-----------GGGFGGGRFGGFGGPGGVGGLGGPGGF----GPGGYPG 148



 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 43/111 (38%), Positives = 53/111 (47%), Gaps = 24/111 (21%)

Query: 48  GDGYNGFGNDGGYG-------GGGPGYS----GGSRGYGSVGQGYGSQGSGYGGSGSY-- 94
           G G  GFG  GG+G       GG    S    GG  G+G+ G G+G +G G+GG  S+  
Sbjct: 47  GGGGGGFGG-GGFGSRSLVGLGGTKSISISVAGGGGGFGAAG-GFGGRGGGFGGGSSFGG 104

Query: 95  -NSYNNG--GGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGG 142
            + ++ G  GGG FGGG    FGG G     G        FGP  GG  GG
Sbjct: 105 GSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGG----PGGFGP--GGYPGG 149



 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 38/94 (40%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 48  GDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGG 107
           G G    G+ GG GGGG    GG    G  G  YGS G   GGS S   Y +GGG    G
Sbjct: 540 GSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSG 599

Query: 108 GSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFG 141
             G S GGS S   +G+    SS+   + G  FG
Sbjct: 600 --GGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFG 631



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 28/65 (43%), Positives = 32/65 (49%), Gaps = 9/65 (13%)

Query: 44  FLGRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGG 103
           F GRG G+ G    G   GGG G+SGG  G G  G   G +  G+GG G       GG G
Sbjct: 89  FGGRGGGFGG----GSSFGGGSGFSGGGFGGGGFG---GGRFGGFGGPGGVGGL--GGPG 139

Query: 104 SFGGG 108
            FG G
Sbjct: 140 GFGPG 144



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/93 (37%), Positives = 45/93 (48%), Gaps = 6/93 (6%)

Query: 80  GYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYN--DFGNYNNQSSNFGPTKG 137
           G G +GS  GG  S  S + G GG   G  G S GG GS +   +G+       +G + G
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS-GGGGSISGGGYGSGGGSGGRYG-SGG 577

Query: 138 GNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSS 170
           G+ GG  S+  GG G    K  + GG  G SSS
Sbjct: 578 GSKGG--SISGGGYGSGGGKHSSGGGSRGGSSS 608



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/122 (33%), Positives = 49/122 (40%), Gaps = 26/122 (21%)

Query: 59  GYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGS 118
           G GGGG G+ G S G   V  G     S +    S  S + GGGG F        GG GS
Sbjct: 11  GRGGGGGGFRGFSSGSAVVSGGSRRSTSSF----SCLSRHGGGGGGF------GGGGFGS 60

Query: 119 YNDFGNYNNQS---------SNFGPT-----KGGNFGGRSSVPCGGGGQYFVKPQNQGGY 164
            +  G    +S           FG       +GG FGG SS   GGG  +       GG+
Sbjct: 61  RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSF--GGGSGFSGGGFGGGGF 118

Query: 165 GG 166
           GG
Sbjct: 119 GG 120



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 8/70 (11%)

Query: 102 GGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQ 161
           GGS G GS S  G S   + +G+   QS +    +GG+ GG S      GG Y     + 
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGS----RGGSGGGGSI----SGGGYGSGGGSG 570

Query: 162 GGYGGSSSSR 171
           G YG    S+
Sbjct: 571 GRYGSGGGSK 580



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 10/64 (15%)

Query: 109 SGSSFGGSG--SYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGG 166
           S ++FGGSG    +  G Y++ SS++G   GG   G S    GGGG       + GGYG 
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYG--SGGRQSG-SRGGSGGGGSI-----SGGGYGS 565

Query: 167 SSSS 170
              S
Sbjct: 566 GGGS 569


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 53/125 (42%), Positives = 62/125 (49%), Gaps = 16/125 (12%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGY----SGGSRGYGSVGQGYGSQG-SGYGGSGSYNSYNNG 100
           G+ + YN     GG GGGG  Y    S  S G GS G GYG+Q  SG GGSG Y   + G
Sbjct: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS-GGGYGNQDQSGGGGSGGYGQQDRG 214

Query: 101 GGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPT-KGGNFGGRSSVPCG--GGGQYFVK 157
           G G   GGSG   GG G     G YN  S  + P  +GG  GGR  +     GG   F  
Sbjct: 215 GRGR--GGSGGGGGGGG-----GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267

Query: 158 PQNQG 162
           P++QG
Sbjct: 268 PRDQG 272



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 44/134 (32%), Positives = 53/134 (39%), Gaps = 20/134 (14%)

Query: 53  GFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQ------GSGYGGSGSYNSYNNGGGGSFG 106
           G+G+ GGYG      S  S G  S   GYG Q         YG S   +SY     GS+ 
Sbjct: 74  GYGSTGGYGSSQSSQS--SYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYS 131

Query: 107 -----GGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQ 161
                GG   S+G   SYN    Y  Q+  +  + GG  GG      GGGG Y     + 
Sbjct: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQ-YNSSSGGGGGG------GGGGNYGQDQSSM 184

Query: 162 GGYGGSSSSRHYQD 175
              GGS      QD
Sbjct: 185 SSGGGSGGGYGNQD 198



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 44/142 (30%), Positives = 54/142 (38%), Gaps = 30/142 (21%)

Query: 46  GRGDGYNGFGND-------GGYGGGGPGYSGGSRGYGSVGQ--GYGSQGSGYG------- 89
           G+   Y G+G         G YG      S G    GS  Q   YG Q   YG       
Sbjct: 92  GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151

Query: 90  --GSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVP 147
             G G  N YN+  GG  GGG G ++G   S          S + G   GG +G +    
Sbjct: 152 PQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS----------SMSSGGGSGGGYGNQDQSG 201

Query: 148 CGGGGQYFVKPQNQGGYGGSSS 169
            GG G Y    Q++GG G   S
Sbjct: 202 GGGSGGY--GQQDRGGRGRGGS 221



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 35/91 (38%), Positives = 37/91 (40%), Gaps = 12/91 (13%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSG-GSRGYGSVGQGYGSQGSGYG-GSGSYNSYNNGGG- 102
           G G GY      GG G GG G    G RG G  G G G  G GY   SG Y     GGG 
Sbjct: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248

Query: 103 ---GSFGGGSGSSFGGSGSYNDFGNYNNQSS 130
              G  GG         G +N FG   +Q S
Sbjct: 249 GGRGGMGGSD------RGGFNKFGGPRDQGS 273



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 44/118 (37%), Positives = 53/118 (44%), Gaps = 30/118 (25%)

Query: 65  PGYSGGSRGYG-----SVGQGYGSQ---------GSGYGGSGSYN---SYNNGGGGSFGG 107
           P Y G  + YG     +  QGYG Q         G G GG G+Y    S  + GGGS GG
Sbjct: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGG 193

Query: 108 -GSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGY 164
            G+    GG GS    G Y  Q    G  +GG+ GG      GGGG Y    ++ GGY
Sbjct: 194 YGNQDQSGGGGS----GGYGQQDRG-GRGRGGSGGGGG----GGGGGY---NRSSGGY 239



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/125 (32%), Positives = 48/125 (38%), Gaps = 15/125 (12%)

Query: 54  FGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGSSF 113
           F   GG G GG G  GG  G G    GYG  GSG GG G + S   GGGG    G     
Sbjct: 375 FNRGGGNGRGGRG-RGGPMGRG----GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCP 429

Query: 114 GGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGG-------GGQYFVKPQNQGGYGG 166
             +    +F   N  +    P   G  GG      GG       GG+      ++GGY G
Sbjct: 430 NPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGR---GGYDRGGYRG 486

Query: 167 SSSSR 171
               R
Sbjct: 487 RGGDR 491



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 34/157 (21%)

Query: 53  GFGNDGGYGGGGPGYSGGSRGYGSVGQG------YG-SQGSGYGGSGSYNSYNNGGGGSF 105
           G+        G   YSG S+   + G G      YG SQ +GYG   +   Y + GG   
Sbjct: 24  GYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGS 83

Query: 106 GGGSGSSFGGSGSYNDFGNY------------NNQSSNFGPTKGG------NFGGRS--- 144
              S SS+G   SY  +G              ++QSS++G  + G      ++GG+    
Sbjct: 84  SQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSY 143

Query: 145 ------SVPCGGGGQYFVKPQNQGGYGGSSSSRHYQD 175
                 + P G G Q      + GG GG     + QD
Sbjct: 144 GQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD 180



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/168 (33%), Positives = 66/168 (39%), Gaps = 58/168 (34%)

Query: 47  RGDGYNGFGND-GGYGGGGP----GYSGGSRGYGSVGQGYGSQGSGYGG---SGSYNSYN 98
           R D   G GN  GG G GGP    GY GG  G G  G G+ S G G GG   +G +   N
Sbjct: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRG-GFPSGGGGGGGQQRAGDWKCPN 430

Query: 99  -----------------------NGGGGSFGGGSGSSF-----GGSGSYNDFGNYNNQSS 130
                                    GGG  G   G ++     GG G Y D G Y  +  
Sbjct: 431 PTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGY-DRGGYRGR-- 487

Query: 131 NFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYG-GSSSSR--HYQD 175
             G  +GG  GGR     GGG        ++GG+G G   SR  H QD
Sbjct: 488 --GGDRGGFRGGR-----GGG--------DRGGFGPGKMDSRGEHRQD 520



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 37/107 (34%), Positives = 47/107 (43%), Gaps = 17/107 (15%)

Query: 78  GQGYGSQGSGYGGSGSYNSYNNGGGGS-FGGGSGSSFGGSGSYNDFGNYNNQSS--NFGP 134
           GQGY  Q S   G  SY+ Y+     S +G  S SS+G S +      Y  QS+   +G 
Sbjct: 22  GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQN----TGYGTQSTPQGYGS 77

Query: 135 TKG--------GNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSSRHY 173
           T G         ++G +SS P  G GQ        G YG SS S  Y
Sbjct: 78  TGGYGSSQSSQSSYGQQSSYP--GYGQQPAPSSTSGSYGSSSQSSSY 122



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)

Query: 45  LGRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYG 89
           +G   G +  G  GGY  GG    GG RG    G+G G +G G+G
Sbjct: 464 MGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG-GFG 507


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 48/110 (43%), Positives = 54/110 (49%), Gaps = 14/110 (12%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSF 105
           GRG G+ G G  GG GGGG G  GG  G+G  G G+G  G G GG G       GGGG  
Sbjct: 334 GRG-GWGGGGGGGGRGGGGGG--GGRGGWGGGGGGWGGGGGGGGGWG------GGGGGGR 384

Query: 106 GGGSG-SSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQY 154
           GG  G   +GG G Y   G Y  +   +G   GG  GG      GGGG Y
Sbjct: 385 GGFQGRGDYGGRGGYGGRGGYGGR--GYGDPYGGGGGGGGG--GGGGGGY 430



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 51/128 (39%), Positives = 59/128 (46%), Gaps = 23/128 (17%)

Query: 47  RGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFG 106
           R +G  G G  GG GGGG G  GG  G G    G+G  G G+GG G       GGGG +G
Sbjct: 328 RQEGGGGRGGWGG-GGGGGGRGGGGGGGGR--GGWGGGGGGWGGGG-------GGGGGWG 377

Query: 107 GGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRS-SVPCGGGGQYFVKPQNQGGYG 165
           GG G   GG G +   G+Y  +    G    G +GGR    P GGGG         GG G
Sbjct: 378 GGGG---GGRGGFQGRGDYGGRGGYGG---RGGYGGRGYGDPYGGGG------GGGGGGG 425

Query: 166 GSSSSRHY 173
           G    R Y
Sbjct: 426 GGGGYRRY 433



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 36/78 (46%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQG-YGSQGSGYGGSGSYNSYNNGGGGS 104
           G G G  G+G  GG GGG  G  GG RG G  G+G YG +G GYGG G Y     G    
Sbjct: 358 GWGGGGGGWGGGGGGGGGWGGGGGGGRG-GFQGRGDYGGRG-GYGGRGGYGGRGYGDPYG 415

Query: 105 FGGGSGSSFGGSGSYNDF 122
            GGG G   GG G Y  +
Sbjct: 416 GGGGGGGGGGGGGGYRRY 433



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 27/55 (49%), Positives = 27/55 (49%), Gaps = 9/55 (16%)

Query: 44  FLGRGDGYNGFGNDGGYGG-GGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSY 97
           F GRGD Y G G  GG GG GG       RGYG    G G  G G GG G Y  Y
Sbjct: 387 FQGRGD-YGGRGGYGGRGGYGG-------RGYGDPYGGGGGGGGGGGGGGGYRRY 433


>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
          Length = 398

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 50/142 (35%), Positives = 67/142 (47%), Gaps = 16/142 (11%)

Query: 52  NGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGS 111
           +G G      GGG G   GS G GS G    + GS  GGS S +S     GGS GG SG+
Sbjct: 235 SGSGGGSSNSGGGSGSQSGSSGSGSNGDN--NNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292

Query: 112 SFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQY---FVKPQNQGGYGGSS 168
           S    GS  D G+ ++  S+ G +  GN GG      GGG  +     KP N+    G S
Sbjct: 293 S---GGSRGDSGSESSWGSSTG-SSSGNHGG-----SGGGNGHKPGCEKPGNEARGSGES 343

Query: 169 SSRHY--QDVLASPKLKEAAPG 188
             + +  Q V ++ +  E +PG
Sbjct: 344 GIQGFRGQGVSSNMRNSETSPG 365



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 52/163 (31%), Positives = 65/163 (39%), Gaps = 49/163 (30%)

Query: 50  GYNGFGNDGGYGGGG---------------PGYSGGSRGYGSVGQGYGSQGS-------- 86
           G+  FG+ GG GG G               PG S GS G    G  +G  G+        
Sbjct: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGT 206

Query: 87  ---------GYGGSGSYN----------SYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNN 127
                    GYG   + N          S + GG  + GGGSGS  G SGS ++ G+ NN
Sbjct: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN-GDNNN 265

Query: 128 QSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSS 170
            SS+ G + G + GG S    GG         N GG  G S S
Sbjct: 266 GSSSGGSSSGSSSGGSSGGSSGGSS------GNSGGSRGDSGS 302



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 46/134 (34%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 50  GYNGFGNDGGYGGGGPGYSGGSRGYGSVGQ-GYGS-----QGSGY-----GGSGSYNSYN 98
           G N  G   G GG G   + G+   G+V Q GYGS     Q  G       GSG  +S +
Sbjct: 185 GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNS 244

Query: 99  NGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKP 158
            GG GS  G SGS   G  +       ++  S+ G + GG+ GG SS   GG        
Sbjct: 245 GGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG-SSGNSGGSRGDSGSE 303

Query: 159 QNQGGYGGSSSSRH 172
            + G   GSSS  H
Sbjct: 304 SSWGSSTGSSSGNH 317



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 33/137 (24%), Positives = 47/137 (34%), Gaps = 13/137 (9%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGS-QGSGYGGSGSYNSYNNGGGGS 104
           G  D       +  +  G  G+  G +    +  G  + +GS  G  G   ++   GG  
Sbjct: 90  GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHG 149

Query: 105 FGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGY 164
             G  G   GG G  N  G        +     G+FG     P G        P  QGG 
Sbjct: 150 IFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMN---PQGA-------PWGQGGN 198

Query: 165 GGSSS-SRHYQDVLASP 180
           GG  +   + Q  +A P
Sbjct: 199 GGPPNFGTNTQGAVAQP 215


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 21/158 (13%)

Query: 52  NGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGSQGSGYGGSGSYNSYNNGGGGSFGGGSGS 111
           +G G      GGG G   GS G GS G    + GS  GGS S +S     GGS GG SG+
Sbjct: 235 SGSGGGSSNSGGGSGSQSGSSGSGSNGDN--NNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292

Query: 112 SFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQY---FVKPQNQGGYGGSS 168
           S    GS  D G+ ++  S+ G +  GN GG      GGG  +     KP N+    G S
Sbjct: 293 S---GGSRGDSGSESSWGSSTG-SSSGNHGG-----SGGGNGHKPGCEKPGNEARGSGES 343

Query: 169 SSRHYQDVLASPKLKEAAP-------GSAERWRRAQAA 199
             + ++    S  ++E +        GS + +R ++ +
Sbjct: 344 GIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETS 381



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 52/163 (31%), Positives = 65/163 (39%), Gaps = 49/163 (30%)

Query: 50  GYNGFGNDGGYGGGG---------------PGYSGGSRGYGSVGQGYGSQGS-------- 86
           G+  FG+ GG GG G               PG S GS G    G  +G  G+        
Sbjct: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGT 206

Query: 87  ---------GYGGSGSYN----------SYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNN 127
                    GYG   + N          S + GG  + GGGSGS  G SGS ++ G+ NN
Sbjct: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN-GDNNN 265

Query: 128 QSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGYGGSSSS 170
            SS+ G + G + GG S    GG         N GG  G S S
Sbjct: 266 GSSSGGSSSGSSSGGSSGGSSGGSS------GNSGGSRGDSGS 302



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 46/134 (34%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 50  GYNGFGNDGGYGGGGPGYSGGSRGYGSVGQ-GYGS-----QGSGY-----GGSGSYNSYN 98
           G N  G   G GG G   + G+   G+V Q GYGS     Q  G       GSG  +S +
Sbjct: 185 GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNS 244

Query: 99  NGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKP 158
            GG GS  G SGS   G  +       ++  S+ G + GG+ GG SS   GG        
Sbjct: 245 GGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG-SSGNSGGSRGDSGSE 303

Query: 159 QNQGGYGGSSSSRH 172
            + G   GSSS  H
Sbjct: 304 SSWGSSTGSSSGNH 317



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 33/137 (24%), Positives = 47/137 (34%), Gaps = 13/137 (9%)

Query: 46  GRGDGYNGFGNDGGYGGGGPGYSGGSRGYGSVGQGYGS-QGSGYGGSGSYNSYNNGGGGS 104
           G  D       +  +  G  G+  G +    +  G  + +GS  G  G   ++   GG  
Sbjct: 90  GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHG 149

Query: 105 FGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGGNFGGRSSVPCGGGGQYFVKPQNQGGY 164
             G  G   GG G  N  G        +     G+FG     P G        P  QGG 
Sbjct: 150 IFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMN---PQGA-------PWGQGGN 198

Query: 165 GGSSS-SRHYQDVLASP 180
           GG  +   + Q  +A P
Sbjct: 199 GGPPNFGTNTQGAVAQP 215


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.130    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,773,225
Number of Sequences: 37866
Number of extensions: 1365051
Number of successful extensions: 18295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 381
Number of HSP's that attempted gapping in prelim test: 5399
Number of HSP's gapped (non-prelim): 4707
length of query: 434
length of database: 18,247,518
effective HSP length: 105
effective length of query: 329
effective length of database: 14,271,588
effective search space: 4695352452
effective search space used: 4695352452
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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