Guide to the Human Genome
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Search of human proteins with 239746270

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239746270 PREDICTED: hypothetical protein XP_002343719 [Homo
sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757272 PREDICTED: hypothetical protein [Homo sapiens]           655   0.0  
gi|239751775 PREDICTED: hypothetical protein [Homo sapiens]           655   0.0  
gi|239746270 PREDICTED: hypothetical protein XP_002343719 [Homo ...   655   0.0  
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          52   7e-07
gi|119395750 keratin 1 [Homo sapiens]                                  50   3e-06
gi|55956899 keratin 9 [Homo sapiens]                                   49   8e-06
gi|195972866 keratin 10 [Homo sapiens]                                 48   1e-05
gi|47132620 keratin 2 [Homo sapiens]                                   47   2e-05
gi|109255251 loricrin [Homo sapiens]                                   47   3e-05
gi|115511036 alpha-kinase 3 [Homo sapiens]                             45   1e-04
gi|109452587 family with sequence similarity 98, member B isofor...    44   2e-04
gi|153792074 proline rich 12 [Homo sapiens]                            44   2e-04
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 41   0.002
gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo ...    41   0.002
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]               41   0.002
gi|192807292 keratin 24 [Homo sapiens]                                 40   0.002
gi|169204521 PREDICTED: hypothetical protein [Homo sapiens]            40   0.002
gi|169205149 PREDICTED: hypothetical protein [Homo sapiens]            40   0.002
gi|169204400 PREDICTED: hypothetical protein [Homo sapiens]            40   0.002
gi|119395754 keratin 5 [Homo sapiens]                                  40   0.004
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    40   0.004
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    40   0.004
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    40   0.004
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    40   0.004
gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo ...    39   0.005
gi|153791670 keratin 76 [Homo sapiens]                                 39   0.006
gi|7657575 sirtuin 1 isoform a [Homo sapiens]                          39   0.006
gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]            39   0.006
gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]            39   0.006
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]        39   0.006

>gi|239757272 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 314

 Score =  655 bits (1691), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA
Sbjct: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60

Query: 61  WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN 120
           WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN
Sbjct: 61  WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN 120

Query: 121 WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR 180
           WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR
Sbjct: 121 WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR 180

Query: 181 VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV 240
           VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV
Sbjct: 181 VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV 240

Query: 241 RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR 300
           RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR
Sbjct: 241 RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR 300

Query: 301 RPGPGAGQGTAVSP 314
           RPGPGAGQGTAVSP
Sbjct: 301 RPGPGAGQGTAVSP 314


>gi|239751775 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 314

 Score =  655 bits (1691), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA
Sbjct: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60

Query: 61  WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN 120
           WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN
Sbjct: 61  WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN 120

Query: 121 WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR 180
           WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR
Sbjct: 121 WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR 180

Query: 181 VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV 240
           VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV
Sbjct: 181 VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV 240

Query: 241 RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR 300
           RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR
Sbjct: 241 RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR 300

Query: 301 RPGPGAGQGTAVSP 314
           RPGPGAGQGTAVSP
Sbjct: 301 RPGPGAGQGTAVSP 314


>gi|239746270 PREDICTED: hypothetical protein XP_002343719 [Homo
           sapiens]
          Length = 314

 Score =  655 bits (1691), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA
Sbjct: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60

Query: 61  WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN 120
           WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN
Sbjct: 61  WGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGN 120

Query: 121 WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR 180
           WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR
Sbjct: 121 WDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSR 180

Query: 181 VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV 240
           VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV
Sbjct: 181 VPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRV 240

Query: 241 RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR 300
           RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR
Sbjct: 241 RRMAWEVISGSTRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARRLSSSRAEFRPR 300

Query: 301 RPGPGAGQGTAVSP 314
           RPGPGAGQGTAVSP
Sbjct: 301 RPGPGAGQGTAVSP 314


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 65/234 (27%), Positives = 89/234 (38%), Gaps = 27/234 (11%)

Query: 10  PPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPAWGGAPPRAL 69
           PP   P+ A  A+ +  A G +  L L  +      P        +SP P  GGAP  + 
Sbjct: 90  PPALSPAPASPARPVSPAPGRR--LSLWAV------PPGPPLSGGLSPDPKPGGAPTSSR 141

Query: 70  PAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVS 129
               P L  P+W   GG     RAG  +  +     G G    +V+           TV+
Sbjct: 142 R---PLLSSPSW---GGPEPEGRAGGGIPGSSSPHPGTGSRRLKVAPPPPA-PKPCKTVT 194

Query: 130 FTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGA 189
            T   + GGG  +G RL    WP   +  + R++G+   AG        +   A AGGG 
Sbjct: 195 -TSGAKAGGGKGAGSRLS---WPE--SEGKPRVKGSKSSAG-TGASVSAAATAAAAGGGG 247

Query: 190 ETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVA-----LPGNQTPSP 238
            TA+ S G G     R K+  R           + PG  A     L    TPSP
Sbjct: 248 STASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSP 301


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 45/146 (30%), Positives = 58/146 (39%), Gaps = 29/146 (19%)

Query: 82  LSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGF 141
           +S GG  G    G     +G  S G+GGG +    GGG   G+ G+     S  G GGG 
Sbjct: 512 ISGGGSRGGGGGGY---GSGGSSYGSGGGSYGSGGGGGGGRGSYGS---GGSSYGSGGGS 565

Query: 142 SGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGIT 201
            G   GG     +         G+G  +G       G R  +G GGG  +    SGGG +
Sbjct: 566 YGSGGGGGGHGSY---------GSGSSSG-------GYRGGSGGGGGGSSGGRGSGGGSS 609

Query: 202 GEGRSKVRGRVEGEAWGSRGTMSPGG 227
           G       G + G    S G  S GG
Sbjct: 610 G-------GSIGGRGSSSGGVKSSGG 628



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 49/153 (32%), Positives = 55/153 (35%), Gaps = 30/153 (19%)

Query: 86  GEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR- 144
           G AG+        S+  R  G GGG F    GGG         SF     G GGGF  R 
Sbjct: 20  GSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGG--------SF-----GAGGGFGSRS 66

Query: 145 --RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITG 202
              LGGS      + S    RG G  +GF    G G     G GGG        GGG  G
Sbjct: 67  LVNLGGSK-----SISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGG 121

Query: 203 EGRSKVRGRVEGEAWGSRG-------TMSPGGV 228
            G     G   G  +G  G          PGG+
Sbjct: 122 FGSG--GGGFGGGGFGGGGYGGGYGPVCPPGGI 152



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 37/122 (30%), Positives = 47/122 (38%), Gaps = 34/122 (27%)

Query: 85  GGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR 144
           GG  G  R       +G  S G+GGG +  S GGG   G+ G+ S +   RGG GG  G 
Sbjct: 542 GGGGGGGRGSY---GSGGSSYGSGGGSYG-SGGGGGGHGSYGSGSSSGGYRGGSGGGGGG 597

Query: 145 RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
             GG              RG+G                 G+ GG+     SS GG+   G
Sbjct: 598 SSGG--------------RGSG----------------GGSSGGSIGGRGSSSGGVKSSG 627

Query: 205 RS 206
            S
Sbjct: 628 GS 629



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 29/101 (28%), Positives = 36/101 (35%), Gaps = 26/101 (25%)

Query: 127 TVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAG 186
           T+S   S  GGGGG+     GGS +            G+G           G    +G G
Sbjct: 511 TISGGGSRGGGGGGYGS---GGSSY------------GSG-----------GGSYGSGGG 544

Query: 187 GGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGG 227
           GG    +  SGG   G G         G   GS G+ S  G
Sbjct: 545 GGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSG 585



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 25/71 (35%), Positives = 28/71 (39%), Gaps = 18/71 (25%)

Query: 78  GPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGG 137
           G ++ S GG  G    G    S G R    GGGG   S GG                RG 
Sbjct: 563 GGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGG--GSSGG----------------RGS 604

Query: 138 GGGFSGRRLGG 148
           GGG SG  +GG
Sbjct: 605 GGGSSGGSIGG 615


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 19/145 (13%)

Query: 83  SVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDS-CRGGGGGF 141
           S GG  G   +G  +RS+  R   +GGGG     GGG +  + G    +   C  GGGG 
Sbjct: 14  SGGGGGGGLGSGGSIRSSYSRFSSSGGGG-----GGGRFSSSSGYGGGSSRVCGRGGGGS 68

Query: 142 SGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGIT 201
            G   GG     + ASS        +  GF    G GSR   GA GG  +++   GGG  
Sbjct: 69  FGYSYGGGSGGGFSASS--------LGGGF----GGGSRGFGGASGGGYSSSGGFGGGF- 115

Query: 202 GEGRSKVRGRVEGEAWGSRGTMSPG 226
           G G     G   G  +G  G    G
Sbjct: 116 GGGSGGGFGGGYGSGFGGFGGFGGG 140



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 46/158 (29%), Positives = 57/158 (36%), Gaps = 21/158 (13%)

Query: 83  SVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFS 142
           S  G+ G+   G    S G  S G  GG +     GG + G  G+   +    GGG G S
Sbjct: 468 SGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG-S 526

Query: 143 GRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAG---GGAETAAASSGGG 199
           G   GG               G G  +G  H  G G     G+G   GG   +   SGGG
Sbjct: 527 GGGSGG---------------GYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571

Query: 200 ITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPS 237
             G   S  RG   G   G  G     G +  G +  S
Sbjct: 572 YGGGSGS--RGGSGGSHGGGSGFGGESGGSYGGGEEAS 607



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 46/153 (30%), Positives = 51/153 (33%), Gaps = 14/153 (9%)

Query: 85  GGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR 144
           GG  G    G    S G    G G GG   SRGG       G+ S   S  G GGG  G 
Sbjct: 482 GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG 541

Query: 145 RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
             GGS              G G   G     G GS    G+GGG    + S GG     G
Sbjct: 542 HSGGS--------------GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHG 587

Query: 205 RSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPS 237
                G   G ++G     S  G    G    S
Sbjct: 588 GGSGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 26/114 (22%)

Query: 99  SAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGG---GGGFSGRRLGGSPWPRWL 155
           S G    G  GGGF  S  GG + G  G+  F  +  GG    GGF G   GGS      
Sbjct: 68  SFGYSYGGGSGGGFSASSLGGGFGG--GSRGFGGASGGGYSSSGGFGGGFGGGS------ 119

Query: 156 ASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVR 209
                   G G   G+    G G     G GGG   A    GG +T   +S ++
Sbjct: 120 --------GGGFGGGY----GSGFGGFGGFGGG---AGGGDGGILTANEKSTMQ 158



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 33/103 (32%), Positives = 39/103 (37%), Gaps = 11/103 (10%)

Query: 135 RGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLD-----GPGSRVPAGAGGGA 189
           R GGGG  G   GGS     + SS  R   +G   G          G GS    G GGG 
Sbjct: 13  RSGGGGGGGLGSGGS-----IRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67

Query: 190 ETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPG 232
               +  GG   G   S + G   G + G  G  S GG +  G
Sbjct: 68  SFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGA-SGGGYSSSG 109


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 45/138 (32%), Positives = 54/138 (39%), Gaps = 17/138 (12%)

Query: 105 EGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGG-----GGFSGRRLGGSPWPRWLASSR 159
           EG+ GGG    RGGG++ G  G  S      GGG     GG SG   GG        SS 
Sbjct: 456 EGSSGGG---GRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGG-------GSSG 505

Query: 160 RRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASS-GGGITGEGRSKVRGRVEGEAWG 218
               G G   G     G G     G GGG+        GGG +G G S   G   G + G
Sbjct: 506 GGSSGGGYGGG-SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564

Query: 219 SRGTMSPGGVALPGNQTP 236
              + S G V    ++ P
Sbjct: 565 GHKSSSSGSVGESSSKGP 582



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 41/110 (37%), Positives = 45/110 (40%), Gaps = 8/110 (7%)

Query: 99  SAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASS 158
           S G  S G  GGG   S GGG   G+ G  S   S  G GGG S    GGS    +   S
Sbjct: 478 SGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS---SGGGYGGGSSSGGHGGSSSGGYGGGS 534

Query: 159 RRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAA-ASSGGGITGEGRSK 207
                G G   G     G GS    G GGG+ +    SS  G  GE  SK
Sbjct: 535 SGG-GGGGYGGG---SSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 130 FTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGA 189
           ++ S  GGGGG  G   GG      ++SS+  + G     GF      GS     +GGG 
Sbjct: 11  YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGF----SGGSFSRGSSGGGC 66

Query: 190 ETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPG 232
              ++   GG+ G G    RG     ++G     S GG +  G
Sbjct: 67  FGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG 109



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 101 GCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRG--GGGGFSGRRLGG 148
           GC    +GG G     GGG++ G+ G+ SF  S  G  GGG F G   GG
Sbjct: 65  GCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGG 114



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 8/51 (15%)

Query: 106 GNGGGGFQVSRG----GGNWDGALGTVSFTDSCRG----GGGGFSGRRLGG 148
           G GGG F+ S G    GG++ G+ G  SF     G    GGGGF G   GG
Sbjct: 79  GFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGG 129



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 33/118 (27%), Positives = 44/118 (37%), Gaps = 4/118 (3%)

Query: 104 SEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIR 163
           S  +GGGG     GGG   G + ++  + S    GGGFS     G  + R  +       
Sbjct: 13  SSRSGGGGGGGGCGGG---GGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGG 69

Query: 164 GTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRG 221
            +G   G     G   R   G+     +   S GGG  G G S   G   G  +G  G
Sbjct: 70  SSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFG-GGSFGGGSFGGGGFGGGG 126



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 5/59 (8%)

Query: 174 LDGPGSRVPAGAGGGA---ETAAASSGGGITGEGRSKVRGRVEGEAW--GSRGTMSPGG 227
           L+G GS    G GGG+        SSGGG +G G     G   G  +  GS G  S GG
Sbjct: 453 LEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGG 511



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 4/67 (5%)

Query: 83  SVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFS 142
           S GG  G + +G      G  S G  GGG     GGG   G+ G  S +    GGG    
Sbjct: 509 SGGGYGGGSSSG----GHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564

Query: 143 GRRLGGS 149
           G +   S
Sbjct: 565 GHKSSSS 571


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 7/136 (5%)

Query: 93  AGVILRSAGCRSEGNGGGGFQVSRGGGNWDGA--LGTVSFTDSCRGGGGGFSGRRLGGSP 150
           +  I  +   ++   G GG   S GGG   G+   G+       RGG GG  G  + G  
Sbjct: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGG--GGSISGGG 562

Query: 151 WPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGI--TGEGRSKV 208
           +     S  R   G G   G     G GS     + GG     +SSGGG    G G S V
Sbjct: 563 YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSV 622

Query: 209 RGRVEGEAWGSRGTMS 224
           +G   GEA+GS  T S
Sbjct: 623 KGS-SGEAFGSSVTFS 637



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 104 SEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIR 163
           S   GGGGF  + G G   G  G      S  GGG GFSG   GG  +         R  
Sbjct: 75  SVAGGGGGFGAAGGFGGRGGGFGG----GSSFGGGSGFSGGGFGGGGF------GGGRFG 124

Query: 164 GTGVPAGFCHLDGPGSRVPAGAGGG 188
           G G P G   L GPG   P G  GG
Sbjct: 125 GFGGPGGVGGLGGPGGFGPGGYPGG 149



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 46/136 (33%), Positives = 51/136 (37%), Gaps = 8/136 (5%)

Query: 99  SAGCRSEGNGGGGFQVSRGGG---NWDGALGTVSFTDSCR--GGGGGFSGRRLGGSPWPR 153
           S   R  G GGGGF+    G    +      T SF+   R  GGGGGF G   G      
Sbjct: 6   SCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVG 65

Query: 154 WLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAAS--SGGGITGEGRSKVRGR 211
              +    I   G   GF    G G R   G GGG+     S  SGGG  G G    R  
Sbjct: 66  LGGTKSISISVAGGGGGFGAAGGFGGR-GGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFG 124

Query: 212 VEGEAWGSRGTMSPGG 227
             G   G  G   PGG
Sbjct: 125 GFGGPGGVGGLGGPGG 140



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 8/79 (10%)

Query: 76  LRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCR 135
           + G  + S GG  G   +G   +       G G GG + S GGG+  G+     +     
Sbjct: 558 ISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGS--- 614

Query: 136 GGGG-----GFSGRRLGGS 149
           GGGG     G SG   G S
Sbjct: 615 GGGGSSSVKGSSGEAFGSS 633


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 61/229 (26%), Positives = 75/229 (32%), Gaps = 24/229 (10%)

Query: 85  GGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR 144
           GG  G    G      G    G+ G G   S GGG   G  G      S  GGGGG  G 
Sbjct: 24  GGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGG----GSSGGGGGGGIGG 79

Query: 145 RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
             GGS        S +   G G   G     G G      +GGG     +S GGG +G G
Sbjct: 80  CGGGS------GGSVKYSGGGGSSGG-----GSGC---FSSGGGGSGCFSSGGGGSSGGG 125

Query: 205 RSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRMAWEVISGSTRDVRRESGARSE 264
                    G + G  G  S GG    G          ++    SG         G    
Sbjct: 126 SGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGS 185

Query: 265 GCTFREPPPADGSDCKFPIS--DGARRLSSSRAEFRPRRPGPGAGQGTA 311
            C +       GS C    S   G+  +SS +       P P  G G++
Sbjct: 186 VCGY----SGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSS 230



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 14/137 (10%)

Query: 100 AGCRSEGNGGGGFQVSRGGGNWDGALGTVSF---------TDSCRGGGGGFSGRRLGGSP 150
           +GC S G GG G   S GGG+  G  G  S          +     GGGGFSG+ +    
Sbjct: 101 SGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQS 160

Query: 151 WPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRG 210
           +    +        +G  +G     G G  V   +GGG+     SSGG  +G   S+   
Sbjct: 161 YGGVSSGG-----SSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVT 215

Query: 211 RVEGEAWGSRGTMSPGG 227
           +       S G  S GG
Sbjct: 216 QTSCAPQPSYGGGSSGG 232



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 46/157 (29%), Positives = 56/157 (35%), Gaps = 15/157 (9%)

Query: 78  GPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGG 137
           G  +   GG  G +       S G    G G GG     GGG   G  G  S       G
Sbjct: 33  GCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSG 92

Query: 138 GGGFSGRRLG----GSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAA 193
           GGG SG   G    G       +S      G G     C   G G     G+ GG     
Sbjct: 93  GGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG---SGCFSSGGG-----GSSGGGSGCF 144

Query: 194 ASSGGGITGEG-RSKVRGRVE--GEAWGSRGTMSPGG 227
           +S GGG +G+  + +  G V   G + G  G  S GG
Sbjct: 145 SSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGG 181



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 42/142 (29%), Positives = 51/142 (35%), Gaps = 19/142 (13%)

Query: 89  GVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGG 148
           GV+  G     +GC S G GGG      GGG+             C GG  G SG     
Sbjct: 163 GVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGS------------GCGGGSSGGSGSGYVS 210

Query: 149 SPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSG---GGITGEGR 205
           S      + + +   G G  +G     G G     G GG +     SSG   G I   G 
Sbjct: 211 SQQVTQTSCAPQPSYGGG-SSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGG 269

Query: 206 SKVRGRVEGEAWGSRGTMSPGG 227
           S   G   G + G  G  S GG
Sbjct: 270 SVCGG---GSSGGGGGGSSVGG 288



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 37/124 (29%), Positives = 54/124 (43%), Gaps = 34/124 (27%)

Query: 85  GGEAGVARAGVI----LRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGG 140
           GG +G + +G +    +    C  + + GGG   S GGG   G+ G+  F+    GGGGG
Sbjct: 198 GGSSGGSGSGYVSSQQVTQTSCAPQPSYGGG---SSGGG---GSGGSGCFSS---GGGGG 248

Query: 141 FSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGA----GGGAETAAASS 196
            SG   G S                G+ +G C + G GS    G+    GGG+    + S
Sbjct: 249 SSGCGGGSS----------------GIGSG-CIISGGGSVCGGGSSGGGGGGSSVGGSGS 291

Query: 197 GGGI 200
           G G+
Sbjct: 292 GKGV 295


>gi|115511036 alpha-kinase 3 [Homo sapiens]
          Length = 1907

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 48/171 (28%), Positives = 60/171 (35%), Gaps = 16/171 (9%)

Query: 102 CRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRR 161
           CR +G  G G     G G W  A   VS    C G      G++   +  P  +    R+
Sbjct: 109 CRHQGRQGSGLGAGPGAGTWAPAPPGVS-KPRCPGRARPGEGQQQVTTARPPAINRGARQ 167

Query: 162 IRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRG 221
            R     AG     GPG      AG      AA+S G   GEG +    R     WG+ G
Sbjct: 168 PRAGAAAAG----RGPG------AGAWRTGEAAASAGPAVGEGGAMGSRRAPSRGWGAGG 217

Query: 222 TMSPGGVALPGNQT--PSPRVRRMAWEV---ISGSTRDVRRESGARSEGCT 267
               GG          PSP  R     V    S S+  +   S  RS  C+
Sbjct: 218 RSGAGGDGEDDGPVWIPSPASRSYLLSVRPETSLSSNRLSHPSSGRSTFCS 268


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 34/102 (33%), Positives = 37/102 (36%), Gaps = 3/102 (2%)

Query: 103 RSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRI 162
           R EG GG G     GGG   G  G         GGGGG+ G   GG  W       R   
Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGF 387

Query: 163 RGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
           +G G   G     G G R   G  G  +      GGG  G G
Sbjct: 388 QGRGDYGG---RGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 44/134 (32%), Positives = 46/134 (34%), Gaps = 22/134 (16%)

Query: 65  PPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGA 124
           PP  +P   PW +       GG  G    G      G R  G GGGG    RGG  W G 
Sbjct: 318 PPPEMP---PWQKRQE--GGGGRGGWGGGG----GGGGRGGGGGGGG----RGG--WGGG 362

Query: 125 LGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAG 184
            G         GGGGG  G   GG    R     R    G G   G     G G   P G
Sbjct: 363 GG------GWGGGGGGGGGWG-GGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG 415

Query: 185 AGGGAETAAASSGG 198
            GGG        GG
Sbjct: 416 GGGGGGGGGGGGGG 429



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 6/54 (11%)

Query: 106 GNGGGGFQV-----SRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRW 154
           G G GGFQ       RGG    G  G   + D   GGGGG  G   GG  + R+
Sbjct: 381 GGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG-GGGGGGGGGYRRY 433



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 24/78 (30%), Positives = 28/78 (35%), Gaps = 8/78 (10%)

Query: 150 PWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVR 209
           P P  +   ++R  G G   G+    G G R   G GGG        GGG  G G     
Sbjct: 317 PPPPEMPPWQKRQEGGGGRGGWGGGGGGGGR-GGGGGGGGRGGWGGGGGGWGGGGGG--- 372

Query: 210 GRVEGEAWGSRGTMSPGG 227
               G  WG  G    GG
Sbjct: 373 ----GGGWGGGGGGGRGG 386


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 63/258 (24%), Positives = 100/258 (38%), Gaps = 48/258 (18%)

Query: 5   AAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPAWGGA 64
           A+ +PPPPPPP+ AL  +   + GG+   +  +  L               + SP  GG 
Sbjct: 296 ASAQPPPPPPPAHAL--QHYLSCGGSYPSMGHRANL---------------ACSPLGGGE 338

Query: 65  PPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQ-------VSRG 117
           P     A  P   GP+    G  AG +       +AG    G GGGG++          G
Sbjct: 339 PSPG--AGEPSKAGPS----GATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTG 392

Query: 118 GGNWDGALGTV--------SFTDSCRGGGG---GFSGRRLGGSPWPRWLASSRRRIRGTG 166
            G +  A G          + T  C+  GG    ++  +  G+      A S  + +G  
Sbjct: 393 KGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLL 452

Query: 167 VPAGFCHLDGPG-----SRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRG 221
            P  +    G G     S+ P+ +GG  +  +     G+    +S    +++G+ +G +G
Sbjct: 453 GPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGL-ATCQSYSPDQLQGQLYGVQG 511

Query: 222 TMSPGGVA-LPGNQTPSP 238
              PG  A   G  T SP
Sbjct: 512 EPYPGPAAHSQGLPTASP 529



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 3    PEAAKRPPPPPPPSEA-LAAKELEAAGGAKEGLDL 36
            P A   PPPPPPP+ A LAA   E A  + E  +L
Sbjct: 1506 PPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 66/278 (23%), Positives = 93/278 (33%), Gaps = 67/278 (24%)

Query: 9   PPPPPPPSEALAAK-----ELEAAGGAKEGLDLKVILHSRLRPDSESAGWAI-------- 55
           PP PPPP   L  +        AA  A E    ++   S   P       A+        
Sbjct: 231 PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIK 290

Query: 56  ---SPSPAWGGAPPRALPAVWPWLR-GPAWLSVGGEAGVARAGVILRSAGCRSEGNG--- 108
               P+ A    PP    A+  +L  G ++ S+G  A +A          C   G G   
Sbjct: 291 HYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLA----------CSPLGGGEPS 340

Query: 109 GGGFQVSRGG--GNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTG 166
            G  + S+ G  G   GA G  +  ++  GGG G      GG    R +  S     G G
Sbjct: 341 PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAG------GGGGGYRPIIQSPGYKTGKG 394

Query: 167 VPAGFCHLDGPGSRVP-------------AGAGGGAETAAASSGGGITGEGRS--KVRGR 211
              G+    G  +R P              G      T  AS  GG  G+  S  + +G 
Sbjct: 395 ---GYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGL 451

Query: 212 VEGEAWG-----------SRGTMSPGGVALPGNQTPSP 238
           +  +A+G           S+     GG   P +  P P
Sbjct: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPP 489


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 53/211 (25%), Positives = 72/211 (34%), Gaps = 38/211 (18%)

Query: 1   MAPEAAK-RPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSP 59
           +AP  A+ R P   P + A  + E+  +G    G +     + + + D E +G    P  
Sbjct: 436 LAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEG----NPQGKEDQEGSGGDYMPMN 491

Query: 60  AWGGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAG---CRSEGNGGGGFQVSR 116
            WG    R                 GG  G    G    S+G   C  EG G  G Q S 
Sbjct: 492 NWGSGNGRGS---------------GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSN 536

Query: 117 GGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDG 176
           G G+  G            GG G   G+R GG               G+G   G     G
Sbjct: 537 GQGS--GGNQCSRDGQGTAGGHGSGGGQRPGGG-------------HGSGGGQGPGDGHG 581

Query: 177 PGSRVPAGAGGGAETAAASSGGGITGEGRSK 207
            G    +G G G+ +   S G G  G+   K
Sbjct: 582 SGGGKNSGGGKGSGSGKGSDGDGERGKSLKK 612



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 35/122 (28%), Positives = 44/122 (36%), Gaps = 29/122 (23%)

Query: 106 GNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGT 165
           G G GG Q S G G+   + G     + C G G G  G +  GS              G 
Sbjct: 498 GRGSGGGQGSNGQGSSSHSSGG----NQCSGEGQGSRGGQ--GS-------------NGQ 538

Query: 166 GVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSP 225
           G     C  DG G+    G+GGG         GG          G+  G+  GS G  + 
Sbjct: 539 GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG----------GQGPGDGHGSGGGKNS 588

Query: 226 GG 227
           GG
Sbjct: 589 GG 590



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 18/60 (30%), Positives = 22/60 (36%), Gaps = 3/60 (5%)

Query: 178 GSRVPAGAGGGAETAAASSGGGITGEGRSKVRG---RVEGEAWGSRGTMSPGGVALPGNQ 234
           G  +P    G      +  G G  G+G S       +  GE  GSRG     G    GNQ
Sbjct: 485 GDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQ 544


>gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo
           sapiens]
          Length = 321

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 46/183 (25%), Positives = 67/183 (36%), Gaps = 27/183 (14%)

Query: 143 GRRLGGSPWPRWLASSRRRIR----------GTGVPAGFCHLDGPGSRVPAGAGGGAETA 192
           GR   G   P+W +S+R   R          G+ V        G G + P      A   
Sbjct: 103 GRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGGGGKKPRRGQKAATAG 162

Query: 193 AASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRMAWEVISGST 252
           A S GGG+   G  K+R R  G+   + G  S GG      +  +   RR  W+ +    
Sbjct: 163 AKSRGGGVRSRGGKKIRRR--GQKAAAAGAKSCGGGGKKPQKARAVGARRRGWKKLRRRG 220

Query: 253 RDVRRESG------ARSEGCTFREPP--------PADGSDCKFPISDGARRLSSSRAEFR 298
           +      G       R +G   R+ P         A G  CK P    A  + S+++  +
Sbjct: 221 KKAAAAGGEKAGKKLRQQGEKGRKKPRRRGQKAAAAGGERCKKPRRQKAAAV-SAKSPKK 279

Query: 299 PRR 301
           PRR
Sbjct: 280 PRR 282


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 48/167 (28%), Positives = 61/167 (36%), Gaps = 33/167 (19%)

Query: 65  PPRALPAVWPWLR---GPAWLSVGGEAGVARAGVILRSAGCRS-------EGNGGGGFQV 114
           PP  +P   PW +   GP     GG  G  R G    S G R         G  GG    
Sbjct: 315 PPPEMP---PWQKRQDGPQQ-QTGGRGG-GRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369

Query: 115 SRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHL 174
            RGGG  +   G   +TD   GGGGG+     GG              R +G   G  H 
Sbjct: 370 GRGGGRGNKHQG--GWTDGGSGGGGGYQD---GG-------------YRDSGFQPGGYHG 411

Query: 175 DGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRG 221
                    G  GG +T+++ +G G  G G  +     +G   G RG
Sbjct: 412 GHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRG 458


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 19/119 (15%)

Query: 86  GEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRR 145
           G  G +  G    ++ C   G   G F     GG++ G  G+ S        GGGF G  
Sbjct: 34  GLGGSSAQGFRGGASSCSLSGGSSGAF-----GGSFGGGFGSCSV-------GGGFGGAS 81

Query: 146 LGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
             G+ +     SS   + G G  +GFC      SR  +GA GG  +     GGG+ G+G
Sbjct: 82  GSGTGFGG--GSSFGGVSGFGRGSGFCG----SSRFSSGATGGFYSYGGGMGGGV-GDG 133



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 31/107 (28%), Positives = 39/107 (36%), Gaps = 10/107 (9%)

Query: 99  SAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASS 158
           S    S   G    +VS GG ++           S +G  GG S   L G     +  S 
Sbjct: 5   SRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSF 64

Query: 159 RRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGR 205
                   V  GF    G G+    G GGG      SS GG++G GR
Sbjct: 65  GGGFGSCSVGGGFGGASGSGT----GFGGG------SSFGGVSGFGR 101


>gi|169204521 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 430

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 52/181 (28%), Positives = 67/181 (37%), Gaps = 25/181 (13%)

Query: 135 RGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAA 194
           R G  G +  R+   P    L++ + + RGTG P G           PA AG G E AAA
Sbjct: 250 RRGLQGTAAGRVRADPDDASLSTDKPQ-RGTGGPLG-----------PAAAGAGTEAAAA 297

Query: 195 SSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRM----AWEVISG 250
              G   G+  ++ RG        S G   PGG      ++   R R      A    + 
Sbjct: 298 HEEGSKAGDSGAEPRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRARGRHRVEADAADAA 357

Query: 251 STRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARR-------LSSSRAEFRPRRPG 303
            T   RR   AR  G   RE      SD +   + G RR        SSS  + RP    
Sbjct: 358 PTAAARRAGRARPRGRRHRE--HGTRSDARAVAAPGQRRGDTEDYLPSSSPHQLRPHSQL 415

Query: 304 P 304
           P
Sbjct: 416 P 416



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 40/142 (28%), Positives = 45/142 (31%), Gaps = 30/142 (21%)

Query: 85  GGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR 144
           GG  G A AG    +A    EG+  G        G     L       SC        G 
Sbjct: 280 GGPLGPAAAGAGTEAAAAHEEGSKAG------DSGAEPRGLAPHGPHPSC--------GE 325

Query: 145 RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
           R  G  W +   S   R RG               RV A A   A TAAA   G     G
Sbjct: 326 RRPGGRWQQRRRSHEGRARGR-------------HRVEADAADAAPTAAARRAGRARPRG 372

Query: 205 RSKVRGRVEGEAWGSRGTMSPG 226
           R   R R  G    +R   +PG
Sbjct: 373 R---RHREHGTRSDARAVAAPG 391


>gi|169205149 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 430

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 52/181 (28%), Positives = 67/181 (37%), Gaps = 25/181 (13%)

Query: 135 RGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAA 194
           R G  G +  R+   P    L++ + + RGTG P G           PA AG G E AAA
Sbjct: 250 RRGLQGTAAGRVRADPDDASLSTDKPQ-RGTGGPLG-----------PAAAGAGTEAAAA 297

Query: 195 SSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRM----AWEVISG 250
              G   G+  ++ RG        S G   PGG      ++   R R      A    + 
Sbjct: 298 HEEGSKAGDSGAEPRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRARGRHRVEADAADAA 357

Query: 251 STRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARR-------LSSSRAEFRPRRPG 303
            T   RR   AR  G   RE      SD +   + G RR        SSS  + RP    
Sbjct: 358 PTAAARRAGRARPRGRRHRE--HGTRSDARAVAAPGQRRGDTEDYLPSSSPHQLRPHSQL 415

Query: 304 P 304
           P
Sbjct: 416 P 416



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 40/142 (28%), Positives = 45/142 (31%), Gaps = 30/142 (21%)

Query: 85  GGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR 144
           GG  G A AG    +A    EG+  G        G     L       SC        G 
Sbjct: 280 GGPLGPAAAGAGTEAAAAHEEGSKAG------DSGAEPRGLAPHGPHPSC--------GE 325

Query: 145 RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
           R  G  W +   S   R RG               RV A A   A TAAA   G     G
Sbjct: 326 RRPGGRWQQRRRSHEGRARGR-------------HRVEADAADAAPTAAARRAGRARPRG 372

Query: 205 RSKVRGRVEGEAWGSRGTMSPG 226
           R   R R  G    +R   +PG
Sbjct: 373 R---RHREHGTRSDARAVAAPG 391


>gi|169204400 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 430

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 52/181 (28%), Positives = 67/181 (37%), Gaps = 25/181 (13%)

Query: 135 RGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAA 194
           R G  G +  R+   P    L++ + + RGTG P G           PA AG G E AAA
Sbjct: 250 RRGLQGTAAGRVRADPDDASLSTDKPQ-RGTGGPLG-----------PAAAGAGTEAAAA 297

Query: 195 SSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRM----AWEVISG 250
              G   G+  ++ RG        S G   PGG      ++   R R      A    + 
Sbjct: 298 HEEGSKAGDSGAEPRGLAPHGPHPSCGERRPGGRWQQRRRSHEGRARGRHRVEADAADAA 357

Query: 251 STRDVRRESGARSEGCTFREPPPADGSDCKFPISDGARR-------LSSSRAEFRPRRPG 303
            T   RR   AR  G   RE      SD +   + G RR        SSS  + RP    
Sbjct: 358 PTAAARRAGRARPRGRRHRE--HGTRSDARAVAAPGQRRGDTEDYLPSSSPHQLRPHSQL 415

Query: 304 P 304
           P
Sbjct: 416 P 416



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 40/142 (28%), Positives = 45/142 (31%), Gaps = 30/142 (21%)

Query: 85  GGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGR 144
           GG  G A AG    +A    EG+  G        G     L       SC        G 
Sbjct: 280 GGPLGPAAAGAGTEAAAAHEEGSKAG------DSGAEPRGLAPHGPHPSC--------GE 325

Query: 145 RLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG 204
           R  G  W +   S   R RG               RV A A   A TAAA   G     G
Sbjct: 326 RRPGGRWQQRRRSHEGRARGR-------------HRVEADAADAAPTAAARRAGRARPRG 372

Query: 205 RSKVRGRVEGEAWGSRGTMSPG 226
           R   R R  G    +R   +PG
Sbjct: 373 R---RHREHGTRSDARAVAAPG 391


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 38/97 (39%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 114 VSRGGGNWDGALGTVSFTDSCR-GGGGGFSGRRLGGSPWPRWLAS--SRRRIRGTGVPAG 170
           VSR GG   G  G VS   +C  GG G  S   LGGS       S  S R   G G   G
Sbjct: 35  VSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGG 94

Query: 171 FCHLDGPGS--RVPAGAGGG-AETAAASSGGGITGEG 204
           +    G GS      GAGGG      A  GGG  G G
Sbjct: 95  YGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPG 131



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 5/102 (4%)

Query: 96  ILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGG--GGFSGRRLGGSPWPR 153
           +L    CR  G G G   +S    +     G+ S      GGG  GG  G   GGS    
Sbjct: 473 LLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSY 532

Query: 154 WLASSRRRIRGTGVP---AGFCHLDGPGSRVPAGAGGGAETA 192
           + +SS     G G+    +GF    G G  V  G+GGG+ ++
Sbjct: 533 YSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSS 574



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 32/114 (28%), Positives = 40/114 (35%), Gaps = 25/114 (21%)

Query: 124 ALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPA 183
           ++   SFT   R GGGG  G                    G    AG C + G GSR   
Sbjct: 26  SVSRTSFTSVSRSGGGGGGG-------------------FGRVSLAGACGVGGYGSRSLY 66

Query: 184 GAGGGAETAAASSGGGI-----TGEGRSKVRGRVEGEAWGSRGTMSPGGVALPG 232
             GG    + ++SGG        G G     G   G  +G  G  + GG  L G
Sbjct: 67  NLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGG-AGGGFGLGG 119



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 7/72 (9%)

Query: 161 RIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSR 220
           R+ G GV  G  ++    S V +G G G+       GGG+ G     + G + G + GS 
Sbjct: 480 RLSGEGV--GPVNISVVTSSVSSGYGSGS-----GYGGGLGGGLGGGLGGGLAGGSSGSY 532

Query: 221 GTMSPGGVALPG 232
            + S GGV L G
Sbjct: 533 YSSSSGGVGLGG 544


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/132 (25%), Positives = 43/132 (32%), Gaps = 36/132 (27%)

Query: 106 GNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGT 165
           G GGGG + SRGG    G  G        +GGGGG++                       
Sbjct: 182 GGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSY--------------------- 220

Query: 166 GVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEG------------RSKVRGRVE 213
               G+    G G     G GGG+    +  G G  G G            +S   G   
Sbjct: 221 ---GGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGG 277

Query: 214 GEAWGSRGTMSP 225
           G +WG R    P
Sbjct: 278 GSSWGGRSNSGP 289



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 28/75 (37%), Positives = 29/75 (38%), Gaps = 8/75 (10%)

Query: 82  LSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVSRGG---GNWDGALGTVSFTDSC---- 134
           LS GG  G    G      G      GGGG   S GG   GN  G  G+ S   S     
Sbjct: 209 LSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPM 268

Query: 135 -RGGGGGFSGRRLGG 148
             GGGGG  G   GG
Sbjct: 269 KSGGGGGGGGSSWGG 283



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 17/45 (37%), Positives = 21/45 (46%), Gaps = 6/45 (13%)

Query: 99  SAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSG 143
           S G    G GGGG     GG +W G   +  +     GGGGG+ G
Sbjct: 264 SYGPMKSGGGGGG-----GGSSWGGRSNSGPYRGG-YGGGGGYGG 302


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 46/177 (25%), Positives = 65/177 (36%), Gaps = 44/177 (24%)

Query: 106 GNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGT 165
           G GGGG     GGG   G+           GGGGG  G   GG+              G 
Sbjct: 249 GGGGGG-----GGGGGGGS-----------GGGGGGGGAGAGGA--------------GA 278

Query: 166 GVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMS- 224
           G  A         +   AG GGG     +S+G G+    R +  G + G   G   ++S 
Sbjct: 279 GAVAAAA----AAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 225 -PGGVALPG-------NQTPSPRVRRMAWEVISGSTRDVRRESGARSEGCTFREPPP 273
              G A  G       NQ PS     +  ++++  +  +R   G+  E  +   PPP
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLN-QLLTSPSPMMRSYGGSYPEYSSPSAPPP 390



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 3   PEAAKRPPPPPPPSE--ALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           PE +    PPPPPS+  + AA    AAGG +    + +          +      + SPA
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL--------GKDMGAQYAAASPA 431

Query: 61  WGGAPPRALPAVWPWLRGP 79
           W  A  R+ PA+ P   GP
Sbjct: 432 WAAAQQRSHPAMSPGTPGP 450



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 101 GCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRR 160
           G    G GGGG     GG    GA+   +   +   GGGG  G   GGS     + SS R
Sbjct: 258 GGGGSGGGGGGGGAGAGGAG-AGAVAAAAAAAAAAAGGGGGGG--YGGSSAGYGVLSSPR 314

Query: 161 RIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGG 199
           + +G G+      + GPG     GA   ++ AA S+ GG
Sbjct: 315 Q-QGGGM------MMGPGG---GGAASLSKAAAGSAAGG 343



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 49/195 (25%), Positives = 66/195 (33%), Gaps = 47/195 (24%)

Query: 85  GGEAGVARAGVILRSAGCRSE---GNGGGGFQVS------------RGGGNW--DGALGT 127
           G  AG A AG +  +A   +    G GGGG+  S            +GGG     G  G 
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA 329

Query: 128 VSFTDSCRGGGGGFSGRRLGGSPWP--------RWLASSRRRIRGTGVPAGFCHLDGPGS 179
            S + +  G   G   R  G +  P        + L S    +R  G    +     P +
Sbjct: 330 ASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSA 387

Query: 180 RVPAGAGGGAETAAASSGGG----ITGEGRSKVRG---RVEGEAWG-----SRGTMSPGG 227
             P  +   ++ AAA +  G      G G  K  G        AW      S   MSPG 
Sbjct: 388 PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG- 446

Query: 228 VALPGNQTPSPRVRR 242
                  TP P + R
Sbjct: 447 -------TPGPTMGR 454


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 46/177 (25%), Positives = 65/177 (36%), Gaps = 44/177 (24%)

Query: 106 GNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGT 165
           G GGGG     GGG   G+           GGGGG  G   GG+              G 
Sbjct: 249 GGGGGG-----GGGGGGGS-----------GGGGGGGGAGAGGA--------------GA 278

Query: 166 GVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMS- 224
           G  A         +   AG GGG     +S+G G+    R +  G + G   G   ++S 
Sbjct: 279 GAVAAAA----AAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 225 -PGGVALPG-------NQTPSPRVRRMAWEVISGSTRDVRRESGARSEGCTFREPPP 273
              G A  G       NQ PS     +  ++++  +  +R   G+  E  +   PPP
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLN-QLLTSPSPMMRSYGGSYPEYSSPSAPPP 390



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 3   PEAAKRPPPPPPPSE--ALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           PE +    PPPPPS+  + AA    AAGG +    + +          +      + SPA
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL--------GKDMGAQYAAASPA 431

Query: 61  WGGAPPRALPAVWPWLRGP 79
           W  A  R+ PA+ P   GP
Sbjct: 432 WAAAQQRSHPAMSPGTPGP 450



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 101 GCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRR 160
           G    G GGGG     GG    GA+   +   +   GGGG  G   GGS     + SS R
Sbjct: 258 GGGGSGGGGGGGGAGAGGAG-AGAVAAAAAAAAAAAGGGGGGG--YGGSSAGYGVLSSPR 314

Query: 161 RIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGG 199
           + +G G+      + GPG     GA   ++ AA S+ GG
Sbjct: 315 Q-QGGGM------MMGPGG---GGAASLSKAAAGSAAGG 343



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 49/195 (25%), Positives = 66/195 (33%), Gaps = 47/195 (24%)

Query: 85  GGEAGVARAGVILRSAGCRSE---GNGGGGFQVS------------RGGGNW--DGALGT 127
           G  AG A AG +  +A   +    G GGGG+  S            +GGG     G  G 
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA 329

Query: 128 VSFTDSCRGGGGGFSGRRLGGSPWP--------RWLASSRRRIRGTGVPAGFCHLDGPGS 179
            S + +  G   G   R  G +  P        + L S    +R  G    +     P +
Sbjct: 330 ASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSA 387

Query: 180 RVPAGAGGGAETAAASSGGG----ITGEGRSKVRG---RVEGEAWG-----SRGTMSPGG 227
             P  +   ++ AAA +  G      G G  K  G        AW      S   MSPG 
Sbjct: 388 PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG- 446

Query: 228 VALPGNQTPSPRVRR 242
                  TP P + R
Sbjct: 447 -------TPGPTMGR 454


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 46/177 (25%), Positives = 65/177 (36%), Gaps = 44/177 (24%)

Query: 106 GNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGT 165
           G GGGG     GGG   G+           GGGGG  G   GG+              G 
Sbjct: 249 GGGGGG-----GGGGGGGS-----------GGGGGGGGAGAGGA--------------GA 278

Query: 166 GVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMS- 224
           G  A         +   AG GGG     +S+G G+    R +  G + G   G   ++S 
Sbjct: 279 GAVAAAA----AAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 225 -PGGVALPG-------NQTPSPRVRRMAWEVISGSTRDVRRESGARSEGCTFREPPP 273
              G A  G       NQ PS     +  ++++  +  +R   G+  E  +   PPP
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLN-QLLTSPSPMMRSYGGSYPEYSSPSAPPP 390



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 3   PEAAKRPPPPPPPSE--ALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           PE +    PPPPPS+  + AA    AAGG +    + +          +      + SPA
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL--------GKDMGAQYAAASPA 431

Query: 61  WGGAPPRALPAVWPWLRGP 79
           W  A  R+ PA+ P   GP
Sbjct: 432 WAAAQQRSHPAMSPGTPGP 450



 Score = 36.2 bits (82), Expect = 0.039
 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 101 GCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRR 160
           G    G GGGG     GG    GA+   +   +   GGGG  G   GGS     + SS R
Sbjct: 258 GGGGSGGGGGGGGAGAGGAG-AGAVAAAAAAAAAAAGGGGGGG--YGGSSAGYGVLSSPR 314

Query: 161 RIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAASSGGG 199
           + +G G+      + GPG     GA   ++ AA S+ GG
Sbjct: 315 Q-QGGGM------MMGPGG---GGAASLSKAAAGSAAGG 343



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 49/195 (25%), Positives = 66/195 (33%), Gaps = 47/195 (24%)

Query: 85  GGEAGVARAGVILRSAGCRSE---GNGGGGFQVS------------RGGGNW--DGALGT 127
           G  AG A AG +  +A   +    G GGGG+  S            +GGG     G  G 
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGA 329

Query: 128 VSFTDSCRGGGGGFSGRRLGGSPWP--------RWLASSRRRIRGTGVPAGFCHLDGPGS 179
            S + +  G   G   R  G +  P        + L S    +R  G    +     P +
Sbjct: 330 ASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSA 387

Query: 180 RVPAGAGGGAETAAASSGGG----ITGEGRSKVRG---RVEGEAWG-----SRGTMSPGG 227
             P  +   ++ AAA +  G      G G  K  G        AW      S   MSPG 
Sbjct: 388 PPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG- 446

Query: 228 VALPGNQTPSPRVRR 242
                  TP P + R
Sbjct: 447 -------TPGPTMGR 454


>gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo
           sapiens]
          Length = 286

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 24/50 (48%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 174 LDGPGSRVPAGA---GGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSR 220
           LDGPG+   A A   GGG  +A    GGG  G GR   RGR  GE  G R
Sbjct: 154 LDGPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGGERGGPR 203



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 40/125 (32%), Positives = 46/125 (36%), Gaps = 8/125 (6%)

Query: 3   PEAAKRPPPPPP-PSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPAW 61
           P+   RPP P P P E      L    G    L  +  LH+ L           + + A 
Sbjct: 81  PDRHPRPPAPAPAPRERARGLRLRTVVGVAGVLVERDDLHALLAIQV-IVQLLCAAAEAR 139

Query: 62  GGAPPRALPAVWPWLRGPAWLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQVS---RGG 118
           G A   A  A    L GP     GG A     G    SAG    G GGGG + S   RGG
Sbjct: 140 GAATLPAAAATTTALDGPG---AGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGG 196

Query: 119 GNWDG 123
           G   G
Sbjct: 197 GERGG 201


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 36/110 (32%), Positives = 43/110 (39%), Gaps = 21/110 (19%)

Query: 82  LSVGGEAGVARAGVILRS-AGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGG 140
           +S+   AG +RAG      + C   G  GGGF     GG++ G  G      S  GG GG
Sbjct: 67  ISISVAAGSSRAGGFGGGRSSCGFAGGYGGGF-----GGSYGGGFGGGRGVGSGFGGAGG 121

Query: 141 FSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAE 190
           F G   GG               G GV  G     GPG   P G  GG +
Sbjct: 122 FGG--AGG-------------FGGPGVFGGPGSFGGPGGFGPGGFPGGIQ 156



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 38/116 (32%), Positives = 48/116 (41%), Gaps = 21/116 (18%)

Query: 83  SVGGEAGVARAGVILRSAGCRSEGNGGG-------GFQVSRGGGNWDGALGTVSFTDSCR 135
           S  G +G +R GV    +G  S G  GG       G+ VS G G+  G  G  S +   R
Sbjct: 514 STSGSSGSSR-GVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYG--GVSSGSTGGR 570

Query: 136 GGGGGF----SGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGG 187
           G  G +    SG RLGG+       S      G G  +G     G GS   +G GG
Sbjct: 571 GSSGSYQSSSSGSRLGGA------GSISVSHSGMGSSSGSIQTSG-GSGYKSGGGG 619



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 5/114 (4%)

Query: 127 TVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGF-CHLDGPGSRVPAGA 185
           T   + S RG  GG SG   GG        SS     G GV  G      G  S    G 
Sbjct: 515 TSGSSGSSRGVFGGVSGSGSGGYKG----GSSSSSSSGYGVSGGSGSGYGGVSSGSTGGR 570

Query: 186 GGGAETAAASSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPR 239
           G      ++SSG  + G G   V     G + GS  T    G    G  + S R
Sbjct: 571 GSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIR 624



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 38/122 (31%), Positives = 43/122 (35%), Gaps = 17/122 (13%)

Query: 114 VSRGGGNWDGALGTVSFTDSCRGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCH 173
           V+R GG   GA G        R G G F  R L       +   S + I    V AG   
Sbjct: 33  VARSGGAGGGACGF-------RSGAGSFGSRSL-------YNLGSNKSI-SISVAAGSSR 77

Query: 174 LDG-PGSRVPAGAGGGAETAAASSGGGITGEGRSKVRG-RVEGEAWGSRGTMSPGGVALP 231
             G  G R   G  GG       S GG  G GR    G    G   G+ G   PG    P
Sbjct: 78  AGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGVFGGP 137

Query: 232 GN 233
           G+
Sbjct: 138 GS 139


>gi|7657575 sirtuin 1 isoform a [Homo sapiens]
          Length = 747

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 38/117 (32%), Positives = 45/117 (38%), Gaps = 13/117 (11%)

Query: 1   MAPEAAKRPPPPPPPSEALAAKELEAAGGAKEGLDLKVILHSRLRPDSESAGWAISPSPA 60
           MA EAA    P   PS A A +E  A+  A E L        R RP  +  G   SP   
Sbjct: 1   MADEAALALQPGGSPSAAGADREA-ASSPAGEPL--------RKRPRRDGPGLERSPGEP 51

Query: 61  WGGAPPRALPAVWPWLRGPA----WLSVGGEAGVARAGVILRSAGCRSEGNGGGGFQ 113
            G AP R +PA      G A    W     EA  A      ++     EG+ G G Q
Sbjct: 52  GGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQ 108


>gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 40/187 (21%)

Query: 135 RGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAA 194
           RG GG          PWP  LA     + G G+    C LDGP + V    G        
Sbjct: 572 RGAGGRLQ------DPWPASLA-----LAGPGIARLGCDLDGPRALVEGLHGRHEGGPLG 620

Query: 195 SSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRMAWEVISGSTRD 254
            +GGG +GEG+   RG                    PG++    R  R      + S   
Sbjct: 621 GAGGGGSGEGQG--RG--------------------PGSRVSVRRSSRAPSSCRAASLAP 658

Query: 255 VRRESGARSEGCTFREPP----PADGSDCKFPISDGAR---RLSSSRAEFRPRRPGPGAG 307
            R  S   +   T   PP      DG    F + D AR   R S+ R   R  RP   A 
Sbjct: 659 PRPASATSAGSPTSPAPPLHMVSTDGCSAAFLVLDSARKGDRRSARRGGPRSWRPSARAS 718

Query: 308 QGTAVSP 314
              + +P
Sbjct: 719 WVRSTTP 725


>gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 40/187 (21%)

Query: 135 RGGGGGFSGRRLGGSPWPRWLASSRRRIRGTGVPAGFCHLDGPGSRVPAGAGGGAETAAA 194
           RG GG          PWP  LA     + G G+    C LDGP + V    G        
Sbjct: 572 RGAGGRLQ------DPWPASLA-----LAGPGIARLGCDLDGPRALVEGLHGRHEGGPLG 620

Query: 195 SSGGGITGEGRSKVRGRVEGEAWGSRGTMSPGGVALPGNQTPSPRVRRMAWEVISGSTRD 254
            +GGG +GEG+   RG                    PG++    R  R      + S   
Sbjct: 621 GAGGGGSGEGQG--RG--------------------PGSRVSVRRSSRAPSSCRAASLAP 658

Query: 255 VRRESGARSEGCTFREPP----PADGSDCKFPISDGAR---RLSSSRAEFRPRRPGPGAG 307
            R  S   +   T   PP      DG    F + D AR   R S+ R   R  RP   A 
Sbjct: 659 PRPASATSAGSPTSPAPPLHMVSTDGCSAAFLVLDSARKGDRRSARRGGPRSWRPSARAS 718

Query: 308 QGTAVSP 314
              + +P
Sbjct: 719 WVRSTTP 725


>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
          Length = 217

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/63 (42%), Positives = 27/63 (42%), Gaps = 14/63 (22%)

Query: 86  GEAGVARAGVILRSAGCRSEGNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGGFSGRR 145
           GE G  R G      G R  G GGGG    RGGG          F     GGGGGF G R
Sbjct: 163 GEKGPPRGG----GRGGRGGGRGGGGRGGGRGGG----------FRGGRGGGGGGFRGGR 208

Query: 146 LGG 148
            GG
Sbjct: 209 GGG 211



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 1/44 (2%)

Query: 106 GNGGGGFQVSRGGGNWDGALGTVSFTDSCRGGGGG-FSGRRLGG 148
           G G GGF    GGG ++    +  F     GGGGG F G   GG
Sbjct: 5   GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGG 48


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.136    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,646,197
Number of Sequences: 37866
Number of extensions: 1119425
Number of successful extensions: 12270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 485
Number of HSP's that attempted gapping in prelim test: 8903
Number of HSP's gapped (non-prelim): 2673
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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