BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo sapiens] (398 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ... 815 0.0 gi|239757987 PREDICTED: hypothetical protein [Homo sapiens] 722 0.0 gi|239755710 PREDICTED: hypothetical protein [Homo sapiens] 397 e-111 gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo ... 96 4e-20 gi|163965366 nascent polypeptide-associated complex alpha subuni... 68 1e-11 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 66 5e-11 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 66 5e-11 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 66 5e-11 gi|110832843 TBP-associated factor 4 [Homo sapiens] 65 8e-11 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 7e-10 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 62 1e-09 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 62 1e-09 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 62 1e-09 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 62 1e-09 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 60 3e-09 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 60 3e-09 gi|7706469 Kruppel-like factor [Homo sapiens] 59 1e-08 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 58 1e-08 gi|58530845 zyxin [Homo sapiens] 58 2e-08 gi|4508047 zyxin [Homo sapiens] 58 2e-08 gi|18959210 WIRE protein [Homo sapiens] 58 2e-08 gi|18079216 CASK interacting protein 1 [Homo sapiens] 57 3e-08 gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ... 57 3e-08 gi|60460889 Myb protein P42POP [Homo sapiens] 57 3e-08 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 57 3e-08 gi|117938768 GNAS complex locus alex [Homo sapiens] 57 4e-08 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 57 4e-08 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 55 9e-08 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 55 9e-08 gi|55750053 atrophin-1 [Homo sapiens] 55 1e-07 >gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo sapiens] Length = 398 Score = 815 bits (2105), Expect = 0.0 Identities = 398/398 (100%), Positives = 398/398 (100%) Query: 1 MVPVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRC 60 MVPVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRC Sbjct: 1 MVPVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRC 60 Query: 61 QRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPAR 120 QRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPAR Sbjct: 61 QRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPAR 120 Query: 121 AGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPP 180 AGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPP Sbjct: 121 AGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPP 180 Query: 181 ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPR 240 ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPR Sbjct: 181 ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPR 240 Query: 241 LRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQ 300 LRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQ Sbjct: 241 LRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQ 300 Query: 301 AAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPA 360 AAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPA Sbjct: 301 AAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPA 360 Query: 361 PALQPYALTRFPASLSLPDLVFTSVGSSLVICLVPTPL 398 PALQPYALTRFPASLSLPDLVFTSVGSSLVICLVPTPL Sbjct: 361 PALQPYALTRFPASLSLPDLVFTSVGSSLVICLVPTPL 398 >gi|239757987 PREDICTED: hypothetical protein [Homo sapiens] Length = 445 Score = 722 bits (1864), Expect = 0.0 Identities = 358/389 (92%), Positives = 361/389 (92%) Query: 10 ENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEG 69 ENADTARLFGT VYTFEVLGALPPDRSPTPRSRVSPGVT LAVGPGNP RCQRSGVPYEG Sbjct: 57 ENADTARLFGTTVYTFEVLGALPPDRSPTPRSRVSPGVTGLAVGPGNPKRCQRSGVPYEG 116 Query: 70 PGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGA 129 PGAPGGQQLRKSRARLPRTR GREDA V RNRDPAEPGSLRPTSLGFPARAGQG+VQGA Sbjct: 117 PGAPGGQQLRKSRARLPRTRPGREDAAVRGRNRDPAEPGSLRPTSLGFPARAGQGQVQGA 176 Query: 130 APGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPG 189 APGR+LRGEPKTPPGRSGPSGGVRSGAGHRAA AEHQLGAGFSVRNGPGPPARLPPAPPG Sbjct: 177 APGRRLRGEPKTPPGRSGPSGGVRSGAGHRAATAEHQLGAGFSVRNGPGPPARLPPAPPG 236 Query: 190 PLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLA 249 P LRPARP P P TCEPPSRKLPPPLPLCRSRWVLAPPP VRPRLRVLTPP Sbjct: 237 PPLRPARPHNPTSRGPGRLLTCEPPSRKLPPPLPLCRSRWVLAPPPTVRPRLRVLTPPFT 296 Query: 250 LRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCS 309 L CALPERGSRTPSTRSAVL RVAGLGTELTLTPSSRRAHGSH LSSERQAAPTRAFCS Sbjct: 297 LLCALPERGSRTPSTRSAVLVDRVAGLGTELTLTPSSRRAHGSHPLSSERQAAPTRAFCS 356 Query: 310 ADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALT 369 ADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALA GAPRGRTPSP PGPAPALQPY+LT Sbjct: 357 ADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALALGAPRGRTPSPGPGPAPALQPYSLT 416 Query: 370 RFPASLSLPDLVFTSVGSSLVICLVPTPL 398 RFPASLSLPDLVFTSVGSSLVICLVPTPL Sbjct: 417 RFPASLSLPDLVFTSVGSSLVICLVPTPL 445 >gi|239755710 PREDICTED: hypothetical protein [Homo sapiens] Length = 402 Score = 397 bits (1021), Expect = e-111 Identities = 227/355 (63%), Positives = 242/355 (68%), Gaps = 20/355 (5%) Query: 54 PGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPT 113 PG + G P G ++ P +G + G P PG P Sbjct: 58 PGTQRGVREVGSPTRDQELRAGSSCGRAARGFPEPGRGGKTQKWGGGTGTPQSPGPCAPQ 117 Query: 114 SLGF---PARAG-QGRVQGAAPGRKLRGEPKTPPGRSGPSGG--VRSGAGHRAAAAEHQL 167 +L P +AG + R+QG + G P+ PG GP+ V G G R Sbjct: 118 ALASLLGPGKAGCRTRLQGGSSG----ASPRRLPGGRGPAAAFAVEPGTGQRP----RNT 169 Query: 168 GAGFSVRNGPGPPARLPPAPPGPLLRP-ARPPRPYFPRPRTPP---TCEPPSRKLPPPLP 223 + R+G P LPPA PL P PP P+ P R P TCEPPSRKLPPPLP Sbjct: 170 SLAQASRSGTVPG--LPPASLQPLRLPYLAPPGPHDPTSRGPGRLLTCEPPSRKLPPPLP 227 Query: 224 LCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLT 283 CRSRWVLAPPP VRPRLRVLTPPLALR ALPERGSRTPSTRSAVLSGRVAGLGTELTLT Sbjct: 228 PCRSRWVLAPPPTVRPRLRVLTPPLALRRALPERGSRTPSTRSAVLSGRVAGLGTELTLT 287 Query: 284 PSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAAL 343 PSSRRAHGSH LSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAAL Sbjct: 288 PSSRRAHGSHPLSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAAL 347 Query: 344 ARGAPRGRTPSPRPGPAPALQPYALTRFPASLSLPDLVFTSVGSSLVICLVPTPL 398 A GAPRGRTPSP PGPAPALQPY LTRFPASLSLPDLVFTSVGSSLVICLVPTPL Sbjct: 348 ALGAPRGRTPSPGPGPAPALQPYTLTRFPASLSLPDLVFTSVGSSLVICLVPTPL 402 >gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo sapiens] Length = 316 Score = 96.3 bits (238), Expect = 4e-20 Identities = 72/196 (36%), Positives = 87/196 (44%), Gaps = 20/196 (10%) Query: 54 PGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPT 113 PG + G P G ++ P +G + G P PG P Sbjct: 58 PGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQ 117 Query: 114 SLGF---PARAG-QGRVQGAAPGRKLRGEPKTPPGRSGPSGG--VRSGAGHRAAAAEHQL 167 +L P +AG + R+QG + G P+ PG GP+ V G G R Sbjct: 118 ALASLLGPGKAGCRARLQGGSSG----ASPRRLPGGRGPAAAFAVEPGTGQRP----RNT 169 Query: 168 GAGFSVRNGPGPPARLPPAPPGPLLRPA-RPPRPYFPRPRTPP---TCEPPSRKLPPPLP 223 + R+G P LPPA PL P PP P+ P R P T EPPSRKLPPPLP Sbjct: 170 SLAQASRSGTVPG--LPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLP 227 Query: 224 LCRSRWVLAPPPPVRP 239 LCRSRWVLAPPPP P Sbjct: 228 LCRSRWVLAPPPPPAP 243 Score = 39.3 bits (90), Expect = 0.006 Identities = 54/196 (27%), Positives = 67/196 (34%), Gaps = 30/196 (15%) Query: 29 GALPPDRSPTPRSRVSPGVTSLAVGPGNP---TRCQRSGVPYEGPGAPGGQQLRKSRARL 85 G +SP P +P + +GPG R Q PGG+ + A Sbjct: 103 GGTGTPQSPGP---CAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVE 159 Query: 86 PRTRQGREDAGVGRRNRDPAEPG----SLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKT 141 P T Q + + + +R PG SL+P + + A G PGR L EP Sbjct: 160 PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREP-- 217 Query: 142 PPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPY 201 P R P L V P PPA PP P P RPPR Sbjct: 218 -PSRKLPP--------------PLPLCRSRWVLAPPPPPA--PPGPNAAAHPPLRPPRAR 260 Query: 202 FPRPRTPPTCE-PPSR 216 P P C PSR Sbjct: 261 LQDPVDPERCPGGPSR 276 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 68.2 bits (165), Expect = 1e-11 Identities = 93/357 (26%), Positives = 117/357 (32%), Gaps = 42/357 (11%) Query: 33 PDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGR 92 P +PTP + P GP P+ P P +P G S P Sbjct: 959 PKWAPTPPAATPPSPKG---GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015 Query: 93 EDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGV 152 + G P G+ P + P+ G G P + GP+ Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075 Query: 153 RSGAGHRAAAAEHQLGAGF---SVRNGPGPPARLPPAPPGPLLRP----------ARPPR 199 GA AA G S + P PPA PP+P G L P A PP Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135 Query: 200 PYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPL---ALRCALPE 256 P PP P + PP P + PPP P TPP L P+ Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSP---KGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192 Query: 257 RGSRTPSTRSAVLSGRVA-----GLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSAD 311 TP+ G +A G T TP S + G A S + A T A Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK--GGLATPSPKGAPTTPA----- 1245 Query: 312 PLPRPPSFVPSLPSPQ-AQGQAVRQPRLLRAALA----RGAPRGRT---PSPRPGPA 360 P P P+ P P+ A P L+ LA +GAP PSP+ GPA Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302 Score = 64.7 bits (156), Expect = 1e-10 Identities = 71/232 (30%), Positives = 91/232 (39%), Gaps = 60/232 (25%) Query: 139 PKTPPGRSGPSGGVRSGAGHRAAAAEHQLG--AGFSVRNGPGPPARLPPAPPGPLLRPAR 196 P TP + P+ + S + +A A G A S + P PPA PP+P G PA Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG---GPAT 956 Query: 197 PPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPE 256 P + P TPP PPS K P P + AP PP TPP P+ Sbjct: 957 PSPKWAP---TPPAATPPSPKGGPATPSPKG----APTPP------AATPP------SPK 997 Query: 257 RGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRP 316 G TPS + G T +TP S + GS A A P P+ Sbjct: 998 GGPATPSPK---------GAPTPPAVTPPSPK--GSPA---------------ATPFPKG 1031 Query: 317 PSFVPSLPSPQAQGQAVRQPRLLRAALARGA---PRGRTPSPRPGPA-PALQ 364 S P+ P +G P L +GA P PSP+ GPA P+L+ Sbjct: 1032 ASTPPAATPPSPKGSPAATP------LPKGAPTTPAATLPSPKGGPATPSLK 1077 Score = 58.5 bits (140), Expect = 1e-08 Identities = 91/361 (25%), Positives = 118/361 (32%), Gaps = 65/361 (18%) Query: 28 LGALPPDRSPTPRSRVSPGVTS-LAVGP--GNPTRCQRSGVPYEGPGAPGGQQLRKSRAR 84 L PP +PT + P LA P G PT P P +P G S Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT------TPAATPPSPKGGLATPSPKG 1193 Query: 85 LPRTRQGREDAGVG-----RRNRDPAEPGSLRPT---SLGFPARAGQGRVQGAAPGRKLR 136 P T + G P P + P+ L P+ G A P + Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP-K 1252 Query: 137 GEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPAR 196 G P TPP + P+ AA L G + G P PP P PA Sbjct: 1253 GGPATPPPKGAPTP---------PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303 Query: 197 PPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPE 256 P P TPP PPS K P PPP P +TPP P Sbjct: 1304 SPPKGAP---TPPAATPPSPKGSPG----------TPPPKGAPTPPAVTPPSPK--GTPT 1348 Query: 257 RGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRP 316 + TPS++ TPSS+ A + + P P Sbjct: 1349 LPATTPSSKGG-------------PTTPSSKEGPTPPAATPSHKGGPAMT-------PPS 1388 Query: 317 PSFVPSLPSPQAQGQAVRQ-PRLLRAALARGAPR--GRTPSPRPGPAPALQPYALTRFPA 373 P P++PSP+ + P + A A R TPS PA+ P +L + PA Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448 Query: 374 S 374 + Sbjct: 1449 T 1449 Score = 57.8 bits (138), Expect = 2e-08 Identities = 96/390 (24%), Positives = 140/390 (35%), Gaps = 65/390 (16%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 PP +PTP + P SL G P P +P G P Sbjct: 1259 PPKGAPTPPAATPP---SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGG 151 + G P + G+ P ++ P+ G + P K G P TP + GP+ Sbjct: 1316 TPPSPKGSPGTPPPK-GAPTPPAVTPPSPKGTPTLPATTPSSK--GGPTTPSSKEGPTPP 1372 Query: 152 VRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLP--PAPPGPLLRPARPPRPYFPRPRTPP 209 AA H+ G + P P R P P+P G PA P P TP Sbjct: 1373 --------AATPSHKGGPAMT----PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420 Query: 210 TCE----PPSRKLPPP----LPLCRSRWVLAPP-----PPVR--PRLRVLTPPLALRCAL 254 T E P L PP + L ++ AP P + P L +TPP Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA 1480 Query: 255 PERGSRTPSTRSAVLSGRVAGLGT----------ELTLTPSSRR---AHGSHALSSERQA 301 P++ + + S + A + G T E+ TPSSRR A + LS + A Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540 Query: 302 --APTRAFCSADPLPRPPSFVPSLPSPQ-----AQGQAVRQPRLLRAALARGAPRGR--- 351 AP A P P++P+P+ + P + + +GAP + Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600 Query: 352 ------TPSPRPGPA-PALQPYALTRFPAS 374 +PSP+ P PA+ P + + PA+ Sbjct: 1601 IPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630 Score = 34.3 bits (77), Expect = 0.20 Identities = 55/276 (19%), Positives = 94/276 (34%), Gaps = 31/276 (11%) Query: 56 NPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSL 115 +P + P E P P ++ A P T +G P+ L P ++ Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA-----------PSPKELLIPPAV 1605 Query: 116 GFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHR-----AAAAEHQLGAG 170 P+ P +G P TP + P+ + + + A+ ++GA Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGAT 1664 Query: 171 FSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWV 230 + P + P A L+ PA P + P P+RK P + Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPA---------PESTPIITAPTRKGPQTKKSSATSPP 1715 Query: 231 LAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAH 290 + P P + + PL+ P + S+++A G+ A + L P +A Sbjct: 1716 ICPDPSAKNGSK---GPLSTVAPAPLLPVQKDSSKTA--KGKDASHSPKGPLAPPESKAS 1770 Query: 291 GSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSP 326 ++ + P S P PP +P PSP Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806 Score = 30.0 bits (66), Expect = 3.8 Identities = 54/245 (22%), Positives = 76/245 (31%), Gaps = 61/245 (24%) Query: 139 PKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVR-NGPGPPARL----PPAPPGPLLR 193 PK P + S G A+ G SV PP + P P G L Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826 Query: 194 PARPPRPYFPRPRT---------PPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVL 244 P P F + P T P+ P P + L+P P Sbjct: 827 PVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP 886 Query: 245 TPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPT 304 TP + + P+ G TP+ + A L++T SS + + +A P Sbjct: 887 TPSV-VNLPFPKEGPATPAPKQA----------PALSMTSSSPK---------KARATPA 926 Query: 305 RAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQ 364 P +P+ PSP+ A P PSP+ GPA Sbjct: 927 ------------PKGIPASPSPKG---------------APTPPAATPPSPKGGPATPSP 959 Query: 365 PYALT 369 +A T Sbjct: 960 KWAPT 964 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 66.2 bits (160), Expect = 5e-11 Identities = 103/358 (28%), Positives = 125/358 (34%), Gaps = 68/358 (18%) Query: 31 LPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQ 90 +P RS R S G + PG + S P+ P PG R P Sbjct: 108 MPKLRSTANRDNDSGGSRPPLLPPGGRST---SAKPFSPPSGPG---------RFPVPSP 155 Query: 91 G-REDAGVGRRNRDPA---EPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRS 146 G R +RNR P + GS +P S+ P + +Q + R G P P G Sbjct: 156 GHRSGPPEPQRNRMPPPRPDVGS-KPDSIPPPVPSTPRPIQSSPHNR---GSPPVPGGPR 211 Query: 147 GPSGGVRSGA--GHRAAAAEHQLGAGFSVRNGP----GPPARLPPAPPGPLL----RPAR 196 PS G G+R A LG G S+R P P + PP PP P +P Sbjct: 212 QPSPGPTPPPFPGNRGTA----LGGG-SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266 Query: 197 PP-----RPYFPRPRTPPTCEPPSRKLPP----PLPLCRSRWVLAPPPPVRPRLRVLTPP 247 PP RP R PP PP PP P P S+ PPPP RP PP Sbjct: 267 PPPPVGNRPSIHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG----PPP 320 Query: 248 LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAF 307 L + + R P R L + PS R+ SER P R Sbjct: 321 LPPSSSGNDETPRLPQ--------RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD- 371 Query: 308 CSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365 PP LP P + R L A + R SPR GP P L P Sbjct: 372 --------PPGRSGPLPPPPPVSRNGSTSRALPAT-PQLPSRSGVDSPRSGPRPPLPP 420 Score = 51.6 bits (122), Expect = 1e-06 Identities = 74/260 (28%), Positives = 93/260 (35%), Gaps = 47/260 (18%) Query: 122 GQGRVQGAAP----GRKLRGEPK--TPPGRSGPSGGVRSGA---GHRAAAAEHQLGAGFS 172 G G G P G G PK + R SGG R G R+ +A+ FS Sbjct: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKP-----FS 142 Query: 173 VRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLA 232 +GPG R P PG P P R P PR +P S +PPP+P + Sbjct: 143 PPSGPG---RFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS--IPPPVP--------S 189 Query: 233 PPPPVR--PRLRVLTPPLALRCALPERGSRT---PSTRSAVLSGRVAGLGTELTLTPSSR 287 P P++ P R +PP+ P G P R L G + +P S Sbjct: 190 TPRPIQSSPHNRG-SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248 Query: 288 RAHGSHALSSERQAAPTRAFCSADPLPRPP-SFVPSL-----PSPQAQGQAVRQPRLLRA 341 R P+RA P P PP PS+ P P Q P R Sbjct: 249 R--------PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300 Query: 342 ALARGAPRGRTPSPRPGPAP 361 + + AP P RPGP P Sbjct: 301 SASSQAPPPPPPPSRPGPPP 320 Score = 47.8 bits (112), Expect = 2e-05 Identities = 86/332 (25%), Positives = 111/332 (33%), Gaps = 96/332 (28%) Query: 64 GVPYEGPGAPG-GQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAG 122 G + G G PG G + +L T D+G R P PG ++ F +G Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLP--PGGRSTSAKPFSPPSG 146 Query: 123 QGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRA--------------AAAEHQLG 168 GR +PG + G P+ R P R G + ++ H G Sbjct: 147 PGRFPVPSPGHR-SGPPEPQRNRMPPP---RPDVGSKPDSIPPPVPSTPRPIQSSPHNRG 202 Query: 169 AGFSVRNGPGPPARLPPAPPGPLLR------------PARPPRPYFPRPRTPPTCEPPSR 216 + V GP P+ P PP P R P P+ RP PPT PSR Sbjct: 203 SP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT---PSR 258 Query: 217 KL---PPPLPLCRSRWVLAPPPPV--RPRL-RVLTPPLALRCALPERGSRTPSTRSAVLS 270 L PPP PPPPV RP + R PP P + ++ P Sbjct: 259 ALDDKPPP-----------PPPPVGNRPSIHREAVPPP------PPQNNKPP-------- 293 Query: 271 GRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQG 330 PS+ R S A P P PPS P P + Sbjct: 294 ------------VPSTPRPSASS---------------QAPPPPPPPSRPGPPPLPPSSS 326 Query: 331 QAVRQPRLLRAALARGAPRGRTPSP-RPGPAP 361 PRL + L+ + PSP R GP P Sbjct: 327 GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358 Score = 44.7 bits (104), Expect = 2e-04 Identities = 72/266 (27%), Positives = 86/266 (32%), Gaps = 62/266 (23%) Query: 30 ALPPDRSPTPRS-RVSPGVTSLAVGPGNPTRCQRSGVPYEGPG----APGGQQLRKS--- 81 ++PP TPR + SP PG P + P PG A GG +R+S Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLS 241 Query: 82 -------RARLPRTRQGRED-------AGVGRR---NRDPAEPGSLRPTSLGFPARAGQG 124 R LP T D VG R +R+ P + P+ Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301 Query: 125 RVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGP-PARL 183 A P P PP R GP S +G+ Q S P P P R Sbjct: 302 ASSQAPP-------PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354 Query: 184 PPAPPGPLLRPARPPRPYFPRPRTPPTCEPP--------SRKLP---------------- 219 P PP P RP P R P R+ P PP SR LP Sbjct: 355 GPLPPPPSERPPPPVRD--PPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412 Query: 220 ---PPLPLCRSRWVLAPPPPVRPRLR 242 PPLP R PPPP +R Sbjct: 413 GPRPPLPPDRPSAGAPPPPPPSTSIR 438 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 66.2 bits (160), Expect = 5e-11 Identities = 103/358 (28%), Positives = 125/358 (34%), Gaps = 68/358 (18%) Query: 31 LPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQ 90 +P RS R S G + PG + S P+ P PG R P Sbjct: 108 MPKLRSTANRDNDSGGSRPPLLPPGGRST---SAKPFSPPSGPG---------RFPVPSP 155 Query: 91 G-REDAGVGRRNRDPA---EPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRS 146 G R +RNR P + GS +P S+ P + +Q + R G P P G Sbjct: 156 GHRSGPPEPQRNRMPPPRPDVGS-KPDSIPPPVPSTPRPIQSSPHNR---GSPPVPGGPR 211 Query: 147 GPSGGVRSGA--GHRAAAAEHQLGAGFSVRNGP----GPPARLPPAPPGPLL----RPAR 196 PS G G+R A LG G S+R P P + PP PP P +P Sbjct: 212 QPSPGPTPPPFPGNRGTA----LGGG-SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266 Query: 197 PP-----RPYFPRPRTPPTCEPPSRKLPP----PLPLCRSRWVLAPPPPVRPRLRVLTPP 247 PP RP R PP PP PP P P S+ PPPP RP PP Sbjct: 267 PPPPVGNRPSIHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG----PPP 320 Query: 248 LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAF 307 L + + R P R L + PS R+ SER P R Sbjct: 321 LPPSSSGNDETPRLPQ--------RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD- 371 Query: 308 CSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365 PP LP P + R L A + R SPR GP P L P Sbjct: 372 --------PPGRSGPLPPPPPVSRNGSTSRALPAT-PQLPSRSGVDSPRSGPRPPLPP 420 Score = 51.6 bits (122), Expect = 1e-06 Identities = 74/260 (28%), Positives = 93/260 (35%), Gaps = 47/260 (18%) Query: 122 GQGRVQGAAP----GRKLRGEPK--TPPGRSGPSGGVRSGA---GHRAAAAEHQLGAGFS 172 G G G P G G PK + R SGG R G R+ +A+ FS Sbjct: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKP-----FS 142 Query: 173 VRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLA 232 +GPG R P PG P P R P PR +P S +PPP+P + Sbjct: 143 PPSGPG---RFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS--IPPPVP--------S 189 Query: 233 PPPPVR--PRLRVLTPPLALRCALPERGSRT---PSTRSAVLSGRVAGLGTELTLTPSSR 287 P P++ P R +PP+ P G P R L G + +P S Sbjct: 190 TPRPIQSSPHNRG-SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248 Query: 288 RAHGSHALSSERQAAPTRAFCSADPLPRPP-SFVPSL-----PSPQAQGQAVRQPRLLRA 341 R P+RA P P PP PS+ P P Q P R Sbjct: 249 R--------PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300 Query: 342 ALARGAPRGRTPSPRPGPAP 361 + + AP P RPGP P Sbjct: 301 SASSQAPPPPPPPSRPGPPP 320 Score = 47.8 bits (112), Expect = 2e-05 Identities = 86/332 (25%), Positives = 111/332 (33%), Gaps = 96/332 (28%) Query: 64 GVPYEGPGAPG-GQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAG 122 G + G G PG G + +L T D+G R P PG ++ F +G Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLP--PGGRSTSAKPFSPPSG 146 Query: 123 QGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRA--------------AAAEHQLG 168 GR +PG + G P+ R P R G + ++ H G Sbjct: 147 PGRFPVPSPGHR-SGPPEPQRNRMPPP---RPDVGSKPDSIPPPVPSTPRPIQSSPHNRG 202 Query: 169 AGFSVRNGPGPPARLPPAPPGPLLR------------PARPPRPYFPRPRTPPTCEPPSR 216 + V GP P+ P PP P R P P+ RP PPT PSR Sbjct: 203 SP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT---PSR 258 Query: 217 KL---PPPLPLCRSRWVLAPPPPV--RPRL-RVLTPPLALRCALPERGSRTPSTRSAVLS 270 L PPP PPPPV RP + R PP P + ++ P Sbjct: 259 ALDDKPPP-----------PPPPVGNRPSIHREAVPPP------PPQNNKPP-------- 293 Query: 271 GRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQG 330 PS+ R S A P P PPS P P + Sbjct: 294 ------------VPSTPRPSASS---------------QAPPPPPPPSRPGPPPLPPSSS 326 Query: 331 QAVRQPRLLRAALARGAPRGRTPSP-RPGPAP 361 PRL + L+ + PSP R GP P Sbjct: 327 GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358 Score = 44.7 bits (104), Expect = 2e-04 Identities = 72/266 (27%), Positives = 86/266 (32%), Gaps = 62/266 (23%) Query: 30 ALPPDRSPTPRS-RVSPGVTSLAVGPGNPTRCQRSGVPYEGPG----APGGQQLRKS--- 81 ++PP TPR + SP PG P + P PG A GG +R+S Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLS 241 Query: 82 -------RARLPRTRQGRED-------AGVGRR---NRDPAEPGSLRPTSLGFPARAGQG 124 R LP T D VG R +R+ P + P+ Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301 Query: 125 RVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGP-PARL 183 A P P PP R GP S +G+ Q S P P P R Sbjct: 302 ASSQAPP-------PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354 Query: 184 PPAPPGPLLRPARPPRPYFPRPRTPPTCEPP--------SRKLP---------------- 219 P PP P RP P R P R+ P PP SR LP Sbjct: 355 GPLPPPPSERPPPPVRD--PPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412 Query: 220 ---PPLPLCRSRWVLAPPPPVRPRLR 242 PPLP R PPPP +R Sbjct: 413 GPRPPLPPDRPSAGAPPPPPPSTSIR 438 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 66.2 bits (160), Expect = 5e-11 Identities = 116/473 (24%), Positives = 152/473 (32%), Gaps = 101/473 (21%) Query: 5 GRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSG 64 GR A R AV E +P P P V S G Sbjct: 221 GRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEG--------- 271 Query: 65 VPYEGPGAP--GGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAG 122 P GPG P GGQ R R R R G + +R A+ + SLG + G Sbjct: 272 -PGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSR--AKKVKMGQLSLGLESGQG 328 Query: 123 QGRVQGA---APGRKLR----GEP--KTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSV 173 QG+ + + P R++ G P K + + + E + + Sbjct: 329 QGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAE 388 Query: 174 RNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRT---PPTCEPPSRKL-PPPLPLCRSRW 229 P PP PL PA P P P P T PP C PP + PPPLP Sbjct: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLP------ 442 Query: 230 VLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTL--TPSSR 287 +PPPP + +PP + + R P T S A G E T TP+ Sbjct: 443 --SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPS 500 Query: 288 RAHGSH--------------------------ALSSERQAAPTRAFCSADP--------- 312 A G + S R R F DP Sbjct: 501 TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVS 560 Query: 313 ------------LPRPPSFVPS-----------LPSPQAQGQAVRQPRLLRAALARGAPR 349 +P+ P+ VPS +P P+ + +R+P +L R P Sbjct: 561 PVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620 Query: 350 GR-TPSPRPGPAPALQPYALTRFPASLSLPDLVFTSVGSSLVI---CLVPTPL 398 P P P P+P P +R P L P FT + L I L P PL Sbjct: 621 PPPAPPPPPAPSPPPAPATSSRRPLLLRAPQ--FTPSEAHLKIYESVLTPPPL 671 Score = 44.3 bits (103), Expect = 2e-04 Identities = 66/248 (26%), Positives = 87/248 (35%), Gaps = 61/248 (24%) Query: 139 PKTPPGRSGPSGGVRSGAGHRAAAAEHQL------GAGFSVRNGPGPPARLP-------- 184 P P S P RS +G R + G F PG P+ L Sbjct: 1844 PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGD 1903 Query: 185 ---PAPPGPLLRPARPPRPYFPRP-----RTPPTCEPPSRKLPPP----LPLCRSRWVLA 232 PAPP R +R P P PRP +PP P ++PPP L + LA Sbjct: 1904 PDFPAPP----RRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA 1959 Query: 233 PPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAV-LSGRVAGLGT-----ELTLTPSS 286 PP P +PP S SA L + LGT E+ + Sbjct: 1960 PPGPAP------SPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAM 2013 Query: 287 RRAHGSHALSSERQAAPTRAF-------CSADPLPRPPSFVPSLP----------SPQAQ 329 +HG SSE +++PT + SA L PS P P ++ Sbjct: 2014 GSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGL--APSATPGAPRIEQLDGVDDGTDSE 2071 Query: 330 GQAVRQPR 337 +AV+QPR Sbjct: 2072 AEAVQQPR 2079 Score = 41.2 bits (95), Expect = 0.002 Identities = 65/216 (30%), Positives = 75/216 (34%), Gaps = 75/216 (34%) Query: 184 PPAPP----GPLLRP---ARPPRPYFPRP-------RTPPTCEPP--------------- 214 PP PP P+LRP PP P P P TPP+ P Sbjct: 551 PPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFR 610 Query: 215 ----SRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLS 270 +R+LPPP P APPPP P +PP A P SR P A Sbjct: 611 WTSLTRELPPPPP--------APPPPPAP-----SPPPA-----PATSSRRPLLLRAP-- 650 Query: 271 GRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQG 330 TPS AH S P A + +P P P P+ P P+A G Sbjct: 651 ----------QFTPS--EAH-LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697 Query: 331 QAVRQPRLLRAALARGAPRGRTP---SPRPGPAPAL 363 R +L R AP TP P APAL Sbjct: 698 ------RTNHLSLPRFAPVVTTPVKAEVSPHGAPAL 727 Score = 38.9 bits (89), Expect = 0.008 Identities = 63/206 (30%), Positives = 73/206 (35%), Gaps = 46/206 (22%) Query: 177 PGPP-ARLPPAPPGPLLRPARP--PRPYF-------PRPRTPPTCEPPSRKLPPPLPLCR 226 P PP A PP+ P PL R P F P PP PP PPP P Sbjct: 581 PSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS 640 Query: 227 SRWVL---APP-PPVRPRLR----VLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGT 278 SR L AP P L+ VLTPP PE A R G Sbjct: 641 SRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTN 700 Query: 279 ELTL--------TPSSRRA--HGSHALSS----------ERQAAPTRAFCSADPLPRPPS 318 L+L TP HG+ ALS+ QA T+ A P P+P Sbjct: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760 Query: 319 FVPSLPSPQAQGQAVRQPRLLRAALA 344 P PSPQ + P L +A +A Sbjct: 761 QPP--PSPQ------QMPPLEKARIA 778 Score = 36.6 bits (83), Expect = 0.041 Identities = 59/222 (26%), Positives = 73/222 (32%), Gaps = 50/222 (22%) Query: 151 GVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPL----LRPARPPRPYFPRPR 206 G R H AA E+Q ++ + P P + P PL L P P R + P Sbjct: 1787 GPREEPAHLEAAEENQ-----TIVHSPAPSSEPPGGEDPPLDTDVLVPGAPER-HSPIQN 1840 Query: 207 TPPTCEPPSRKLPPPLPLCRSRWVLAPP---PPVRPRLRVLTPPLALRCALPERGSRTPS 263 P P S PPP P S + P P RP V P LP GS Sbjct: 1841 LDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGP------LPSPGS---- 1890 Query: 264 TRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPP----SF 319 PSS H + A P R+ + PRPP + Sbjct: 1891 --------------------PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWAS 1930 Query: 320 VPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAP 361 P SPQ + V P + AL + P P P P P Sbjct: 1931 PPLKTSPQLR---VPPPTSVVTALTPTSGELAPPGPAPSPPP 1969 Score = 34.3 bits (77), Expect = 0.20 Identities = 76/289 (26%), Positives = 90/289 (31%), Gaps = 58/289 (20%) Query: 3 PVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQR 62 P S E++ T+R V G P PR GV + R Sbjct: 2020 PGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPR 2079 Query: 63 S-GVPYEGPGAPGGQQLRKS--RARLP------------RTRQGREDAGVGRRNRD--PA 105 G P GPG L + RAR P + G D G G R PA Sbjct: 2080 GQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPA 2139 Query: 106 EPGSLRPTSLGFPARAGQGRVQGAA-PGRKLRGEPKTPPGRS---GPSGGVRSGAGHRAA 161 P L ++ QG A P R P P R GP+ A + Sbjct: 2140 PP-------LANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKII 2192 Query: 162 AAEHQLGAGFSVRNGPG----PPARLPPAPP--------------GPLLRP---ARPPRP 200 ++LG F G G PP + PP PP GPLL RP Sbjct: 2193 LV-NKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRP 2251 Query: 201 YFPRPRTPPTCEPPSRKLPPPLPLCRSRWVL--------APPPPVRPRL 241 P P P T S PP R + V APPP PRL Sbjct: 2252 APPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRL 2300 Score = 31.6 bits (70), Expect = 1.3 Identities = 67/254 (26%), Positives = 82/254 (32%), Gaps = 74/254 (29%) Query: 53 GPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSL-- 110 GPG+ R + G P G G GG+ R + A R R G +P E +L Sbjct: 12 GPGS-ARGRFPGRP-RGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLR 69 Query: 111 ---------RPTSLGFPARA----GQGRVQGAAPGRKLRGEPKTPPGRSGPS-------- 149 R L R G+GR +G P R E ++ G S Sbjct: 70 LLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSD 129 Query: 150 -----GGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPA--------- 195 +RS + A G G + P PP RL P P PA Sbjct: 130 EDVAPSSLRSALRSQRGRAPR--GRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTE 187 Query: 196 -----------RPPRPYFPRPRTPPTCEPP----SRKLPPPLPL--CRSRW---VLA--- 232 R P PR R CEP SR PP P CR + V+A Sbjct: 188 RMVQALTELLRRAQAPQAPRSR---ACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAA 244 Query: 233 -------PPPPVRP 239 PPPPV P Sbjct: 245 VTIPKPEPPPPVVP 258 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 65.5 bits (158), Expect = 8e-11 Identities = 76/256 (29%), Positives = 96/256 (37%), Gaps = 33/256 (12%) Query: 139 PKTPPGRSGPSGGVRSG--AGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPA- 195 P+TP R+ +G + + +G A AA GAG G P P PP RP Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAA----GAG-PAAPAEGAPGAAPEPPPAGRARPGG 99 Query: 196 ----RPPRPYFPRPRTPPTCEPPSRKLPPP--------LPLCRSRWVLAPPPPVRPRLRV 243 RP P RP P PP+ KL PP P+ + V A P P Sbjct: 100 GGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK 159 Query: 244 LTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAP 303 P AL P G+ AG G TL S+ + HA AAP Sbjct: 160 PAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA------AAP 213 Query: 304 TRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGP-APA 362 + + P P LP P A G ++ P + AA A AP +P P P APA Sbjct: 214 AVSLVNNGPAALLP-----LPKPAAPGTVIQTPPFVGAA-APPAPAAPSPPAAPAPAAPA 267 Query: 363 LQPYALTRFPASLSLP 378 P PA+L+ P Sbjct: 268 AAPPPPPPAPATLARP 283 Score = 48.9 bits (115), Expect = 8e-06 Identities = 82/333 (24%), Positives = 99/333 (29%), Gaps = 76/333 (22%) Query: 98 GRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGR--------------------KLRG 137 G PA P P + P AG+ R G P R KLR Sbjct: 69 GAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP 128 Query: 138 EPKTPPGRSGP---SGGVRSGAGHRAAAAEHQLG-AGFSVRNGPGPPARLPPAPPGPLLR 193 P+ G P + V +G A G A + R GPGP P PGP Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG---PGPGPGPGPG 185 Query: 194 PARPPRP----------------YFPRPRTPPTCEPPSRKLPPPLPLCRSRWV------- 230 P +P P + P P+ LP P P + Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245 Query: 231 -LAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLS---GRVAGLGTELTLTPSS 286 APP P P +PP A A P P A L+ G AG T P Sbjct: 246 AAAPPAPAAP-----SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300 Query: 287 RRAHGSHALSSERQAAPTR---AFCSADPLP-------------RPPSFVPSLPSPQAQG 330 A + + AP A S P P P V P AQ Sbjct: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360 Query: 331 QAVRQPRLLRAALARG-APRGRTPSPRPGPAPA 362 A P A++ G +G PSP P PA Sbjct: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPA 393 Score = 40.0 bits (92), Expect = 0.004 Identities = 94/389 (24%), Positives = 111/389 (28%), Gaps = 87/389 (22%) Query: 29 GALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPY-EGPGAPGGQQLRKSRARLPR 87 GA P P P R PG G P QR G P P P G ++ R P Sbjct: 84 GAAP---EPPPAGRARPG-------GGGP---QRPGPPSPRRPLVPAGPAPPAAKLRPPP 130 Query: 88 TRQGREDAGVGRR-----NRDPAEPGSLRPTS-LGFPARAGQGRVQGAAPGRKLRGEPKT 141 A V +PA G +P ARAG G G PG P Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG------PGP 184 Query: 142 PPGRSGPSGGVRSGAGHRAAAAEHQLGAGFS--VRNGPGP-------------------- 179 PG+ G ++ G A H A V NGP Sbjct: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244 Query: 180 ---------------------PARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKL 218 PA PP PP ARPP P PPT P + Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP----GHPAGPPTAAP---AV 297 Query: 219 PPPLPLCRSRWVLAPPPPV----RPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVA 274 PPP A P P P P A P G + S + V + A Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357 Query: 275 GLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVR 334 T P+S A S + Q A P P P+ +P + R Sbjct: 358 A-QTLAASGPASTAA--SMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414 Query: 335 QPRL----LRAALARGAPRGRTPSPRPGP 359 P +RA L R P P P Sbjct: 415 TPTATTSGIRATLTPTVLAPRLPQPPQNP 443 Score = 38.5 bits (88), Expect = 0.011 Identities = 85/370 (22%), Positives = 120/370 (32%), Gaps = 32/370 (8%) Query: 19 GTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQL 78 GT + T +GA P P +P + A P P + PG P G Sbjct: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA--RPPGHPAGPPT 292 Query: 79 RKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGA-APGRKLRG 137 P Q AG PA P G + G G A APG K Sbjct: 293 AAPAVPPPAAAQNGGSAGAA-----PA-PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE- 345 Query: 138 EPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRP--- 194 PK + P+ + +G + AA +G P P A PPAP P P Sbjct: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL-PSPAAVPPPAPGTPTGLPKGA 404 Query: 195 --------ARPPRPYFP--RPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVL 244 +R P R PT P PP P + L PP V R Sbjct: 405 AGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQL-PPGMVLVRSENG 463 Query: 245 TPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPT 304 + + AL + ++ + ++ R A + + S+ +A G+ ++ RQ PT Sbjct: 464 QLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIA--RQVTPT 521 Query: 305 RAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQ 364 PS Q QP+L+ A+ A G + + G Sbjct: 522 TIIKQVSQAQTTVQ-----PSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTV 576 Query: 365 PYALTRFPAS 374 P A T A+ Sbjct: 577 PGATTTSSAA 586 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 62.4 bits (150), Expect = 7e-10 Identities = 99/362 (27%), Positives = 126/362 (34%), Gaps = 41/362 (11%) Query: 28 LGALPPDRSPTPRSRVSPGVTSLAVGP---GNPTRCQRSGVPYEGPGAPGGQQLRKSRAR 84 L AL P + PR +P + L+ P +P+ +S P P P L A Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336 Query: 85 -LPRTRQGRE-DAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKT- 141 LP + PA P S TSLG P + P L P Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396 Query: 142 ------PPGRSGPSGGVRSGAGHRA--------AAAEHQLGAGFSVRNGPGPPARLPPAP 187 PP ++ PS A A A H L A FS P PP + P +P Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSP 454 Query: 188 PG--PLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLT 245 P P+ A PP P PP PPS PP+ + APPP P L++ Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514 Query: 246 PPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTR 305 PP AL TP ++ L A + +PS+ S + QA P Sbjct: 515 PPPQAPPAL-----ATPPLQA--LPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPPVL 566 Query: 306 AFCSADPLPRPPSF----VPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAP 361 A P PP+ P P +V PR L ALA G P P P P+ Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR-LTLALAPGPP----PPPSRSPSS 621 Query: 362 AL 363 L Sbjct: 622 TL 623 Score = 54.7 bits (130), Expect = 1e-07 Identities = 90/374 (24%), Positives = 124/374 (33%), Gaps = 54/374 (14%) Query: 21 AVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRK 80 A ++F L P +P P++ + + L P P S + P AP + Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435 Query: 81 SRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPK 140 +A A P P + P+ A +V + P Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495 Query: 141 TPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLP------PAPPGPLLRP 194 TPP ++ P + A ++ P PPA P P+ P+ Sbjct: 496 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555 Query: 195 ARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCA- 253 A PP P+ PP P ++PP P + PP P V P L L A Sbjct: 556 ATPP------PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609 Query: 254 -LPERGSRTPSTRSAVLSG-RVAGLGTELTLTPSSRRAHGS------------------- 292 P SR+P S+ LSG +AG + T TP R + S Sbjct: 610 GPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 666 Query: 293 HALSSERQAAPTRAFCSAD--PLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRG 350 H + R AP AF A PLP PP+ P A G L P Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG----SADG--------LCTIYETEGPES 714 Query: 351 RTPSP---RPGPAP 361 TP+P PGP+P Sbjct: 715 ATPAPGALDPGPSP 728 Score = 54.3 bits (129), Expect = 2e-07 Identities = 102/358 (28%), Positives = 122/358 (34%), Gaps = 61/358 (17%) Query: 34 DRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSR----ARLPRTR 89 +R+P P SPG S PG + R PG G + LR S AR T Sbjct: 101 ERAP-PAKNTSPGPVS---SPGRASGTTR-------PGPLGQKGLRISAEETVARGKATE 149 Query: 90 QGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTP-PGRSGP 148 + A RD + P P+ PA A + R G G P P GP Sbjct: 150 APKRSALSAGARRDTSGPTPGTPS----PAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205 Query: 149 SGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTP 208 V S + H P P AR P+ G L RPA P + Sbjct: 206 RKSVSSASEHSTTE--------------PSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251 Query: 209 PTCEPPSRKLPPPLPLCRSR------WVLAPP---PPVRPRLRVLTP----PLALRCALP 255 P PS + P P S+ L PP PP + L P PLA Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311 Query: 256 ERGSRTPSTRSAV--LSGRVAGLGTELTLTPSSRRAHGS-HALSSERQAAPTRAFCS--A 310 S+ P T A S L T L L P S A S L S P++A S + Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371 Query: 311 DPLPRPPSFVPSLP-SPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYA 367 L SF+PS P SP A P L L AP P P +P L P A Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ--AP------PSPPASPPLSPLA 421 Score = 50.1 bits (118), Expect = 4e-06 Identities = 98/381 (25%), Positives = 128/381 (33%), Gaps = 64/381 (16%) Query: 33 PDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGR 92 P SP P V+P + G R + E G GG + +S R TR Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLA----ERAGGIGGATIPESAPRAGPTRS-- 82 Query: 93 EDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGV 152 AG RN P S P S GR + A P + P + PGR+ SG Sbjct: 83 --AGTSSRN-----PASRPPAS---------GRGERAPPAKNTSPGPVSSPGRA--SGTT 124 Query: 153 RSGA----GHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTP 208 R G G R +A E +V G A A R P P P P Sbjct: 125 RPGPLGQKGLRISAEE-------TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177 Query: 209 PTCEPPSRK--LPPPLPLCRSRWVLAPPPPVRPRLRVLTP---------PLALRCALPER 257 + LP P P R R PP PR V + P A R Sbjct: 178 RRSRAAGTEVGLPRPAPSARPR-----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232 Query: 258 GSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPP 317 G + P++RS LS L + PS+R + A S+ + +A P Sbjct: 233 GLQRPASRS--LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290 Query: 318 SFVPSL----------PSPQAQGQAVRQPRLLRAALARGAP-RGRTPSPRPGPAPALQPY 366 P+L PSP A Q+ P L + + TP P P+P+ P Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS 350 Query: 367 ALTRFPASLSLPDLVFTSVGS 387 T + P TS+GS Sbjct: 351 LQTLPSPPATPPSQATTSLGS 371 Score = 48.5 bits (114), Expect = 1e-05 Identities = 101/411 (24%), Positives = 126/411 (30%), Gaps = 90/411 (21%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 P +P+P VG P R P EGP S + Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAG-QGRVQGAAPGRKLRGEPK---------- 140 R AG G + R + S T L PAR+G R AP + +PK Sbjct: 227 RPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285 Query: 141 TPPGRSG----------------PSGGVRSGAGHRAAAAEHQ--LGAGFSVRNGPGPPAR 182 TPP + PS ++S A A H L + PP+ Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS- 344 Query: 183 LPPAPPGPLLRPARPPRP------------------YFPRP-----RTPPTCEPPSRKLP 219 P APP P+ P P + P P TPP PP+ LP Sbjct: 345 -PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403 Query: 220 PPLPLCRSRWVLAPP-PPVRPRLRVLTPP-------LALRCALPERGSRTPSTRSAVLSG 271 P + APP PP P L L P LA+ L S PS Sbjct: 404 P---------LQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQAPFS 453 Query: 272 RVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVP----SLPSPQ 327 A + TP S QA P+ A P PP+ P + P PQ Sbjct: 454 PPASPPVSPSATPPS-------------QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 328 AQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALTRFPASLSLP 378 A P L + P TP + P+P F S SLP Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551 Score = 37.7 bits (86), Expect = 0.018 Identities = 51/165 (30%), Positives = 68/165 (41%), Gaps = 29/165 (17%) Query: 223 PLCRSRWVLAPPPPVRPR---------LRVL-------TPPLALR------CALPERGSR 260 P R+ +L P PP PR LRVL PLA R +PE R Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 261 TPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFV 320 TRSA S R + + RA + S ++P RA + P P + Sbjct: 77 AGPTRSAGTSSR--NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 321 P-SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPG-PAPAL 363 S A+G+A P+ R+AL+ GA R T P PG P+PA+ Sbjct: 135 RISAEETVARGKATEAPK--RSALSAGARRD-TSGPTPGTPSPAM 176 Score = 32.0 bits (71), Expect = 1.0 Identities = 52/182 (28%), Positives = 62/182 (34%), Gaps = 29/182 (15%) Query: 33 PDRSPTPR--SRVSPGVTSLAVGPGNPTRCQRS-GVPYEGPGAPGGQQLRKSRARLPRTR 89 P R PTP + VS +LA+ PG P RS GP G S R Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645 Query: 90 QGREDAGVGRR---------------NRDPAEPGSLRPTS---LGFPARAGQGRVQGAAP 131 + G +R PA P + R L +P G G G Sbjct: 646 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 705 Query: 132 GRKLRG-EPKTP-PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPG 189 + G E TP PG P + G AA A GAG S R+ ARL P G Sbjct: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGA----GAGASSRSPK--QARLGELPLG 759 Query: 190 PL 191 L Sbjct: 760 AL 761 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 61.6 bits (148), Expect = 1e-09 Identities = 88/345 (25%), Positives = 115/345 (33%), Gaps = 85/345 (24%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 PP P P P + L G P+ + P G G PG L+ Sbjct: 257 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ------------ 304 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQ-GAAPGRKLRGEPKTPPGRSGPSG 150 AG ++ P +P G P +A QG+ G +P Sbjct: 305 ---AGPLLQHPGPPQP-------FGLPPQASQGQAPLGTSP------------------- 335 Query: 151 GVRSGAGHRAAAAEH---QLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRT 207 AAA H QL A S PP R P PP PL P P P P P+ Sbjct: 336 ---------AAAYPHTSLQLPASQSALQSQQPP-REQPLPPAPLAMPHIKPPPTTPIPQL 385 Query: 208 PPTCEPPSRKLPP----PLPLCRSRWVLAPPPPVRPRLRVLT--------PPLAL---RC 252 P P + K PP P P + L PPP ++P + T PPL L Sbjct: 386 P---APQAHKHPPHLSGPSPFSMNA-NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441 Query: 253 ALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADP 312 LP ++ P + L P+S G H ++ + A F P Sbjct: 442 PLPSSPAQPPGLTQS----------QNLPPPPASHPPTGLHQVAPQPPFA-QHPFVPGGP 490 Query: 313 LPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRP 357 P P PS +P A QP AA + G+ G + P P Sbjct: 491 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 535 Score = 44.7 bits (104), Expect = 2e-04 Identities = 71/263 (26%), Positives = 93/263 (35%), Gaps = 36/263 (13%) Query: 130 APGRKLRGEPKTP-PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPP 188 AP G P+ P PG + + V A+ A +Q A P P + AP Sbjct: 196 APSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP----TAPVPHTHIQQAPA 251 Query: 189 GPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPP- 247 L P RPP P+ P P P PP PL S + P +P L PP Sbjct: 252 ---LHPQRPPSPH-PPPHPSPH--------PPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 299 Query: 248 ---LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPT 304 L L G P S A LGT +P++ H S L + + A + Sbjct: 300 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT----SPAAAYPHTSLQLPASQSALQS 355 Query: 305 RAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSP-----RPGP 359 + PLP P +P + P P+L + P PSP P Sbjct: 356 QQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 411 Query: 360 APALQPYA--LTRFPASLSLPDL 380 PAL+P + T P S P L Sbjct: 412 PPALKPLSSLSTHHPPSAHPPPL 434 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 61.6 bits (148), Expect = 1e-09 Identities = 88/345 (25%), Positives = 115/345 (33%), Gaps = 85/345 (24%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 PP P P P + L G P+ + P G G PG L+ Sbjct: 811 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ------------ 858 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQ-GAAPGRKLRGEPKTPPGRSGPSG 150 AG ++ P +P G P +A QG+ G +P Sbjct: 859 ---AGPLLQHPGPPQP-------FGLPPQASQGQAPLGTSP------------------- 889 Query: 151 GVRSGAGHRAAAAEH---QLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRT 207 AAA H QL A S PP R P PP PL P P P P P+ Sbjct: 890 ---------AAAYPHTSLQLPASQSALQSQQPP-REQPLPPAPLAMPHIKPPPTTPIPQL 939 Query: 208 PPTCEPPSRKLPP----PLPLCRSRWVLAPPPPVRPRLRVLT--------PPLAL---RC 252 P P + K PP P P + L PPP ++P + T PPL L Sbjct: 940 P---APQAHKHPPHLSGPSPFSMNA-NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995 Query: 253 ALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADP 312 LP ++ P + L P+S G H ++ + A F P Sbjct: 996 PLPSSPAQPPGLTQS----------QNLPPPPASHPPTGLHQVAPQPPFA-QHPFVPGGP 1044 Query: 313 LPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRP 357 P P PS +P A QP AA + G+ G + P P Sbjct: 1045 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 1089 Score = 44.7 bits (104), Expect = 2e-04 Identities = 71/263 (26%), Positives = 93/263 (35%), Gaps = 36/263 (13%) Query: 130 APGRKLRGEPKTP-PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPP 188 AP G P+ P PG + + V A+ A +Q A P P + AP Sbjct: 750 APSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP----TAPVPHTHIQQAPA 805 Query: 189 GPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPP- 247 L P RPP P+ P P P PP PL S + P +P L PP Sbjct: 806 ---LHPQRPPSPH-PPPHPSPH--------PPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853 Query: 248 ---LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPT 304 L L G P S A LGT +P++ H S L + + A + Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT----SPAAAYPHTSLQLPASQSALQS 909 Query: 305 RAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSP-----RPGP 359 + PLP P +P + P P+L + P PSP P Sbjct: 910 QQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 965 Query: 360 APALQPYA--LTRFPASLSLPDL 380 PAL+P + T P S P L Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPL 988 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 61.6 bits (148), Expect = 1e-09 Identities = 88/345 (25%), Positives = 115/345 (33%), Gaps = 85/345 (24%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 PP P P P + L G P+ + P G G PG L+ Sbjct: 811 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ------------ 858 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQ-GAAPGRKLRGEPKTPPGRSGPSG 150 AG ++ P +P G P +A QG+ G +P Sbjct: 859 ---AGPLLQHPGPPQP-------FGLPPQASQGQAPLGTSP------------------- 889 Query: 151 GVRSGAGHRAAAAEH---QLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRT 207 AAA H QL A S PP R P PP PL P P P P P+ Sbjct: 890 ---------AAAYPHTSLQLPASQSALQSQQPP-REQPLPPAPLAMPHIKPPPTTPIPQL 939 Query: 208 PPTCEPPSRKLPP----PLPLCRSRWVLAPPPPVRPRLRVLT--------PPLAL---RC 252 P P + K PP P P + L PPP ++P + T PPL L Sbjct: 940 P---APQAHKHPPHLSGPSPFSMNA-NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995 Query: 253 ALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADP 312 LP ++ P + L P+S G H ++ + A F P Sbjct: 996 PLPSSPAQPPGLTQS----------QNLPPPPASHPPTGLHQVAPQPPFA-QHPFVPGGP 1044 Query: 313 LPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRP 357 P P PS +P A QP AA + G+ G + P P Sbjct: 1045 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 1089 Score = 44.7 bits (104), Expect = 2e-04 Identities = 71/263 (26%), Positives = 93/263 (35%), Gaps = 36/263 (13%) Query: 130 APGRKLRGEPKTP-PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPP 188 AP G P+ P PG + + V A+ A +Q A P P + AP Sbjct: 750 APSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP----TAPVPHTHIQQAPA 805 Query: 189 GPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPP- 247 L P RPP P+ P P P PP PL S + P +P L PP Sbjct: 806 ---LHPQRPPSPH-PPPHPSPH--------PPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853 Query: 248 ---LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPT 304 L L G P S A LGT +P++ H S L + + A + Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT----SPAAAYPHTSLQLPASQSALQS 909 Query: 305 RAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSP-----RPGP 359 + PLP P +P + P P+L + P PSP P Sbjct: 910 QQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 965 Query: 360 APALQPYA--LTRFPASLSLPDL 380 PAL+P + T P S P L Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPL 988 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 61.6 bits (148), Expect = 1e-09 Identities = 109/399 (27%), Positives = 147/399 (36%), Gaps = 65/399 (16%) Query: 3 PVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQR 62 P R RS + AR + T A RS TP R S T G R Sbjct: 567 PATRGRSRSRTPARRGRSRSRT----PARRRSRSRTPTRRRSRSRTPARRGRS------R 616 Query: 63 SGVPYEGPGAPGGQQLRKSRARLPRTRQGRE----DAGVGR-RNRDPAEPGSLRPTSLGF 117 S P R+SR+R P R GR A GR R+R PA G R + Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRT--- 673 Query: 118 PARAGQGRVQGAAPGRKLRGEPKTPP-GRSGPSGGVRSGAGH-RAAAAEHQLGAGFSVRN 175 PAR GR + P R+ R +TP GRS VR G H R + G+ +N Sbjct: 674 PARRS-GRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKN 732 Query: 176 GPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAP-- 233 R + P ++ +R R + P K L L RS +P Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISS------RRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786 Query: 234 -----PPPVR-------PRLRVLTPPLALRCAL---PERGSRTPSTRS--------AVLS 270 PP R P+ + TPP R + P++ S+TPS +S V S Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846 Query: 271 GRVAGLGT-------ELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSL 323 G G+ E ++TP R S + P+R CS PR S P Sbjct: 847 GTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPR 906 Query: 324 PSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPA 362 SP QP+ ++A + +PR R+ S P+P+ Sbjct: 907 QSPSRSSSP--QPK-VKAII---SPRQRSHSGSSSPSPS 939 Score = 43.5 bits (101), Expect = 3e-04 Identities = 104/437 (23%), Positives = 150/437 (34%), Gaps = 93/437 (21%) Query: 32 PPDRSPTP-RSRVSPGVTS--------------LAVGPGNPTRCQRSGVPYEGPGAPGGQ 76 P RS TP R R SP V+S A P T +R P P G Sbjct: 1714 PETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP---KPRGL 1770 Query: 77 QLRKSRARLPRTRQGREDAGVG---------RRNRDPAEPGSLRPTSLGFPARAGQGRVQ 127 Q +SR+R +TR R G +R+R + R G+ +R+ + Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES 1830 Query: 128 GAAPGRKLRGEPKTPP-------GRSGPSGGVRSG-----AGHRAAAAEHQLGAGFSVRN 175 R+ RG +TPP R+ P+ RS A HR + + L + R+ Sbjct: 1831 SRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRS 1890 Query: 176 GPGPPARL----------------------------PPAPPGPLLRPARPPRPYFPRPRT 207 P +R P R P R RT Sbjct: 1891 RTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRT 1950 Query: 208 PPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSA 267 PP SR PP+ RSR P R R R T P+ R + R S RS Sbjct: 1951 PPVTRRRSRSRTPPVTRRRSR--SRTSPITRRRSRSRTSPVTRRRS-RSRTSPVTRRRSR 2007 Query: 268 VLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLP-RPPSFVPSLPSP 326 + V + P+ RR S R+ + +R+ PL R S + + Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS-----PLAIRRRSRSRTPRTA 2062 Query: 327 QAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALTRFPASLSLPDLVFTSVG 386 + + R P +R A G+ R+ S P PA + ++ +R P ++ Sbjct: 2063 RGKRSLTRSPPAIRRRSASGSSSDRSRSATP---PATRNHSGSRTPP---------VALN 2110 Query: 387 SSLVIC-----LVPTPL 398 SS + C + PTPL Sbjct: 2111 SSRMSCFSRPSMSPTPL 2127 Score = 39.7 bits (91), Expect = 0.005 Identities = 88/373 (23%), Positives = 123/373 (32%), Gaps = 72/373 (19%) Query: 26 EVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSG----------VPYEG------ 69 E+ LP S RS SPG+ G G P+R SG P G Sbjct: 1426 EMKDGLPRTPSRRSRSGSSPGLRD---GSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDS 1482 Query: 70 -PGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPG----SLRPTSLGFPARAGQG 124 P Q + R+R P + + +R R +E ++ T LG +R+G Sbjct: 1483 SPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSS 1542 Query: 125 RVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPP---- 180 + P +P RS S A R + R+G P Sbjct: 1543 QELDVKPSA-------SPQERSESDSSPDSKAKTRTPLRQRS-------RSGSSPEVDSK 1588 Query: 181 ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPR 240 +RL P R P +PR P + S P P AP P PR Sbjct: 1589 SRLSPRRS----RSGSSPEVK-DKPRAAPRAQSGSDSSPEPK---------APAPRALPR 1634 Query: 241 LRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSS------RRAHGSHA 294 R PE S T S+ R A G+ + P + RR + Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694 Query: 295 LSSERQAAPTRAFCSADPLPRPPSFVP---------SLPSPQAQGQAVRQPRLLRAALAR 345 R+A +R SA P S P S P P + ++ R+ R + + Sbjct: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTK 1754 Query: 346 GAPR-GRTPSPRP 357 R GR+PSP+P Sbjct: 1755 TTSRRGRSPSPKP 1767 Score = 38.9 bits (89), Expect = 0.008 Identities = 73/320 (22%), Positives = 103/320 (32%), Gaps = 17/320 (5%) Query: 37 PTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAG 96 P +SR P S P + + S +P + R R + E A Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737 Query: 97 VGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGA 156 R +R S R + R+ + +G R KT R G Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST 1797 Query: 157 GHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSR 216 R + + R G G +R P R R RTPPT SR Sbjct: 1798 SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG----RSRTPPTSRKRSR 1853 Query: 217 KLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGL 276 P P RSR +P R R R PL R R +R++ +S R + Sbjct: 1854 SRTSPAPWKRSRSRASPATHRRSRSRT---PLISR--------RRSRSRTSPVSRRRSRS 1902 Query: 277 GTELTLTPSSRRAHGSHALSSERQAAPT--RAFCSADPLPRPPSFVPSLPSPQAQGQAVR 334 T +T S RA S + P R S P R S + P + + ++ Sbjct: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962 Query: 335 QPRLLRAALARGAPRGRTPS 354 P R + +R +P R S Sbjct: 1963 PPVTRRRSRSRTSPITRRRS 1982 Score = 36.2 bits (82), Expect = 0.053 Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 9/144 (6%) Query: 220 PPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTE 279 P P + V +P P + +R PP +R R+ S+ S+ S + + Sbjct: 2569 PVQPEVALKRVPSPTPAPKEAVREGRPP---EPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625 Query: 280 LTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSP-QAQGQAVRQP-R 337 + + SS + S + SS ++P+ A LP+P S P P P + + ++ R+P Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS--PKKPPPGERRSRSPRKPID 2683 Query: 338 LLR--AALARGAPRGRTPSPRPGP 359 LR +L+ R PSP+P P Sbjct: 2684 SLRDSRSLSYSPVERRRPSPQPSP 2707 Score = 33.1 bits (74), Expect = 0.45 Identities = 83/369 (22%), Positives = 114/369 (30%), Gaps = 49/369 (13%) Query: 35 RSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGRED 94 RSPTP+S+ + T +S + A SR+R Sbjct: 230 RSPTPKSK-RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288 Query: 95 AGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPP-GRSGPSGGVR 153 + R+ PA R G+G + PG P +P PS Sbjct: 289 TALAGRSPSPAS------------GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336 Query: 154 S-GAGHRAAAAEHQLGAGFSVRNGPGPPARLP------PAPPGPLLRPARPPRPYFPRPR 206 + +A + GP PPA P P PL P P Sbjct: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396 Query: 207 TPPTCEPPSRKLPPPLPLCRSRWVLAP-PPPVRPRLRVLTPPLALRCALPERGSRTPSTR 265 PT + K P LP S P P P + + P + + A P GS + Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA-PAPGSHREISS 455 Query: 266 SAVLSGRVAGLG---TELTLTPSSR----RAHGSHALSSERQAAPTRAFCSADPLP---- 314 S R G + TPS R R+ + R PT+ S P Sbjct: 456 SPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRR 515 Query: 315 ----------RPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQ 364 R P SPQ G + R R +R A RGR+ S +PA + Sbjct: 516 SRSAQRWGRSRSPQRRGRSRSPQRPGWS-RSRNTQRRGRSRSARRGRSHS----RSPATR 570 Query: 365 PYALTRFPA 373 + +R PA Sbjct: 571 GRSRSRTPA 579 Score = 32.0 bits (71), Expect = 1.0 Identities = 90/343 (26%), Positives = 121/343 (35%), Gaps = 47/343 (13%) Query: 79 RKSRARLP----RTRQGREDAGVGRRNRDPAEPGSLRPT-SLGFPARAGQGRVQGAAPGR 133 R+SR+R P R + R RR+R P + R + S P + R + +P Sbjct: 1956 RRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR-TSPVT 2014 Query: 134 KLRGEPKTPPG-----RSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPA--RLPPA 186 + R +TPP RS R + R+ A + + R G + R PPA Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA 2074 Query: 187 --------PPGPLLRPARPPRPY-FPRPRTPPTCEPPSRKL--------PPPLPLCRSRW 229 R A PP RTPP SR P PL CRS Sbjct: 2075 IRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPG 2134 Query: 230 VLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRA 289 +L P R + VL A + G R P + + A L LT S Sbjct: 2135 MLEPLGSSRTPMSVLQQ--AGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISL-- 2190 Query: 290 HGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPR 349 G+ AA A S P P P + SL + A A R P +A A Sbjct: 2191 -GTARPPPSMSAAGLAARMSQVPAPVP---LMSLRTAPAANLASRIP--AASAAAMNLAS 2244 Query: 350 GRTPSPRPGPAPALQPYALTRFPASLSLPDLVF--TSVGSSLV 390 RTP+ P A +R PA+ + +L T+V S V Sbjct: 2245 ARTPA-----IPTAVNLADSRTPAAAAAMNLASPRTAVAPSAV 2282 Score = 31.6 bits (70), Expect = 1.3 Identities = 33/141 (23%), Positives = 51/141 (36%), Gaps = 15/141 (10%) Query: 123 QGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPAR 182 +GR P ++ R + S S S + ++++ + S + P+ Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS- 2650 Query: 183 LPPAPPGPLLRPARPPRPYFPRPRTP---PTCEPPSRKLPPPLPLCRSRWVLAPPPPVRP 239 PA PGP P+P +P P E SR P+ R L+ P R Sbjct: 2651 --PAKPGPQA---------LPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 2699 Query: 240 RLRVLTPPLALRCALPERGSR 260 R P + + ERGSR Sbjct: 2700 RPSPQPSPRDQQSSSSERGSR 2720 Score = 30.4 bits (67), Expect = 2.9 Identities = 52/191 (27%), Positives = 68/191 (35%), Gaps = 26/191 (13%) Query: 204 RPRTPPTCEPPSRKLPPPLPLCRS--RWVLAPPPPVRPRLRVLTPPLALRCALPERG--- 258 R RTP T SR P RS RW + P R R R P R +R Sbjct: 496 RSRTP-TKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS 554 Query: 259 ---------SRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHG-SHALSSERQAAPTRAFC 308 SR+P+TR S A G + TP+ RR+ + R P R Sbjct: 555 RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARR-- 612 Query: 309 SADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPR---PGPAPALQP 365 R S P+ + + R+ R A G R RTP+ R PA + Sbjct: 613 -----GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRG 667 Query: 366 YALTRFPASLS 376 + +R PA S Sbjct: 668 RSRSRTPARRS 678 Score = 28.9 bits (63), Expect = 8.5 Identities = 72/305 (23%), Positives = 102/305 (33%), Gaps = 43/305 (14%) Query: 102 RDPAEP-----GSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRS--GPSGGVRS 154 R P P G+ P +L + G G AA P+ P + GP + Sbjct: 2288 RTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT 2347 Query: 155 G----AGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPAR------PPRPYFPR 204 AG R AAA S R P +P PL R PP R Sbjct: 2348 APVNIAGSRTAAALAPASLT-SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRAR 2406 Query: 205 PRTPPTCEPPSRKLPPPLPLCRSRWVLAPP----PPVRPRLRVLTPPL---ALRCAL--- 254 RTPP+ SR P SR AP PP + + R P RC + Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQT 2466 Query: 255 -PERGSRTPSTRSAVLSGRVAG-------------LGTELTLTPSSRRAHGSHALSSERQ 300 P GS++ S+ + + AG +++ P+S A AL++ + Sbjct: 2467 TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQP 2526 Query: 301 AAPTR-AFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGP 359 A R + S+ S S S + G + + R PSP P P Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586 Query: 360 APALQ 364 A++ Sbjct: 2587 KEAVR 2591 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 60.5 bits (145), Expect = 3e-09 Identities = 96/357 (26%), Positives = 120/357 (33%), Gaps = 61/357 (17%) Query: 28 LGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPR 87 L AL P + PR +P + L+ P + P AP S LP Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSP----------LATPSPSAPPSPSAPPSLQTLPS 317 Query: 88 TRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKT------ 141 PA P S TSLG P + P L P Sbjct: 318 P---------------PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362 Query: 142 -PPGRSGPSGGVRSGAGHRA--------AAAEHQLGAGFSVRNGPGPPARLPPAPPG--P 190 PP ++ PS A A A H L A FS P PP + P +PP P Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSPPASPP 420 Query: 191 LLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLAL 250 + A PP P PP PPS PP+ + APPP P L++ PP Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480 Query: 251 RCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSA 310 AL TP ++ L A + +PS+ S + QA P A Sbjct: 481 PPAL-----ATPPLQA--LPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPPVLAAPLL 532 Query: 311 DPLPRPPSF----VPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPAL 363 P PP+ P P +V PR L ALA G P P P P+ L Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPR-LTLALAPGPP----PPPSRSPSSTL 584 Score = 54.7 bits (130), Expect = 1e-07 Identities = 90/374 (24%), Positives = 124/374 (33%), Gaps = 54/374 (14%) Query: 21 AVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRK 80 A ++F L P +P P++ + + L P P S + P AP + Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396 Query: 81 SRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPK 140 +A A P P + P+ A +V + P Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456 Query: 141 TPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLP------PAPPGPLLRP 194 TPP ++ P + A ++ P PPA P P+ P+ Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516 Query: 195 ARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCA- 253 A PP P+ PP P ++PP P + PP P V P L L A Sbjct: 517 ATPP------PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570 Query: 254 -LPERGSRTPSTRSAVLSG-RVAGLGTELTLTPSSRRAHGS------------------- 292 P SR+P S+ LSG +AG + T TP R + S Sbjct: 571 GPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627 Query: 293 HALSSERQAAPTRAFCSAD--PLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRG 350 H + R AP AF A PLP PP+ P A G L P Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG----SADG--------LCTIYETEGPES 675 Query: 351 RTPSP---RPGPAP 361 TP+P PGP+P Sbjct: 676 ATPAPGALDPGPSP 689 Score = 53.9 bits (128), Expect = 2e-07 Identities = 98/379 (25%), Positives = 126/379 (33%), Gaps = 56/379 (14%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 P +P+P VG P R P EGP S + Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAG-QGRVQGAAPGRKLRGEPK---------- 140 R AG G + R + S T L PAR+G R AP + +PK Sbjct: 218 RPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 276 Query: 141 TPPGR-SGPSGGVRSGA--GHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPA-R 196 TPP + + P+ G S + + +A A S++ P PPA P L P + Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336 Query: 197 PPRPYFPRP-----RTPPTCEPPSRKLPPPLPLCRSRWVLAPP-PPVRPRLRVLTPP--- 247 + P P TPP PP+ LPP + APP PP P L L P Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPP---------LQAPPSPPASPPLSPLATPSPQ 387 Query: 248 ----LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAP 303 LA+ L S PS A + TP S QA P Sbjct: 388 APNALAVHL-LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-------------QAPP 433 Query: 304 TRAFCSADPLPRPPSFVP----SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGP 359 + A P PP+ P + P PQA P L + P TP + P Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493 Query: 360 APALQPYALTRFPASLSLP 378 +P F S SLP Sbjct: 494 SPPASFPGQAPFSPSASLP 512 Score = 53.5 bits (127), Expect = 3e-07 Identities = 106/392 (27%), Positives = 130/392 (33%), Gaps = 93/392 (23%) Query: 34 DRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSR----ARLPRTR 89 +R+P P SPG S PG + R PG G + LR S AR T Sbjct: 92 ERAP-PAKNTSPGPVS---SPGRASGTTR-------PGPLGQKGLRISAEETVARGKATE 140 Query: 90 QGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTP-PGRSGP 148 + A RD + P P+ PA A + R G G P P GP Sbjct: 141 APKRSALSAGARRDTSGPTPGTPS----PAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196 Query: 149 SGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPA------------- 195 V S + H P P AR P+ G L RPA Sbjct: 197 RKSVSSASEHSTTE--------------PSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 Query: 196 -------------RPPRPYFPRPR-----TPPTCEPPSRKLPPPL-PLCRSRWVLAPPPP 236 P P P+P+ PP PP + P L PL S LA P P Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSP 300 Query: 237 VRPRLRVLTPPLALRCALPERGSRTPSTRSAVL-SGRVAGLGTELTLTPSSRRAHGSHAL 295 P P L LP + PS + L S + + L P S A Sbjct: 301 SAPPSPSAPPSLQ---TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA------ 351 Query: 296 SSERQAAPTRAFCSADPLPRPPSFVP----SLPSPQAQGQAVRQPRLLRAALARGAPRGR 351 + QA P A P PP+ P + PSPQA P L L + AP Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA-------PNALAVHLLQ-APFSP 403 Query: 352 TPSP---RPGPAPALQPYALTRFPASLSLPDL 380 PSP P PA P + + P S + P L Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435 Score = 50.4 bits (119), Expect = 3e-06 Identities = 86/331 (25%), Positives = 119/331 (35%), Gaps = 49/331 (14%) Query: 70 PGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGA 129 P P ++ + + R G+G + P + PT P +G+G + A Sbjct: 38 PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA-GPTRTSRPPASGRG--ERA 94 Query: 130 APGRKLRGEPKTPPGRSGPSGGVRSGA----GHRAAAAEHQLGAGFSVRNGPGPPARLPP 185 P + P + PGR+ SG R G G R +A E +V G A Sbjct: 95 PPAKNTSPGPVSSPGRA--SGTTRPGPLGQKGLRISAEE-------TVARGKATEAPKRS 145 Query: 186 APPGPLLRPARPPRPYFPRPRTPPTCEPPSRK--LPPPLPLCRSRWVLAPPPPVRPRLRV 243 A R P P P P + LP P P R R PP PR V Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-----PPTEGPRKSV 200 Query: 244 LTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAP 303 + E + PS + GL R A S + S+ ++P Sbjct: 201 --------SSASEHSTTEPSPAARRRPSAGGGL---------QRPASRSLSSSATPLSSP 243 Query: 304 TRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLR----AALARGAPRGR---TPSPR 356 R+ SA PR P+ PS P P+ QA+R P++ AA A G TPSP Sbjct: 244 ARSGPSARGTPRAPAH-PSQPKPKGL-QALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 Query: 357 PGPAPALQPYALTRFPASLSLPDLVFTSVGS 387 P+P+ P T + P TS+GS Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGS 332 Score = 34.3 bits (77), Expect = 0.20 Identities = 47/159 (29%), Positives = 66/159 (41%), Gaps = 26/159 (16%) Query: 223 PLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLG----- 277 P R+ +L P PP PR PP AL G+ R L+ R G+G Sbjct: 17 PAARAPGLLTPRPPGSPR----PPPPVTPAALRVLGAAGAVGRKP-LAERAGGIGGATIP 71 Query: 278 --------TELTLTPSS---RRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVP-SLPS 325 T + P+S RA + S ++P RA + P P + S Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 131 Query: 326 PQAQGQAVRQPRLLRAALARGAPRGRTPSPRPG-PAPAL 363 A+G+A P+ R+AL+ GA R T P PG P+PA+ Sbjct: 132 TVARGKATEAPK--RSALSAGARRD-TSGPTPGTPSPAM 167 Score = 32.0 bits (71), Expect = 1.0 Identities = 52/182 (28%), Positives = 62/182 (34%), Gaps = 29/182 (15%) Query: 33 PDRSPTPR--SRVSPGVTSLAVGPGNPTRCQRS-GVPYEGPGAPGGQQLRKSRARLPRTR 89 P R PTP + VS +LA+ PG P RS GP G S R Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606 Query: 90 QGREDAGVGRR---------------NRDPAEPGSLRPTS---LGFPARAGQGRVQGAAP 131 + G +R PA P + R L +P G G G Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 666 Query: 132 GRKLRG-EPKTP-PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPG 189 + G E TP PG P + G AA A GAG S R+ ARL P G Sbjct: 667 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGA----GAGASSRSPK--QARLGELPLG 720 Query: 190 PL 191 L Sbjct: 721 AL 722 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 60.1 bits (144), Expect = 3e-09 Identities = 70/235 (29%), Positives = 84/235 (35%), Gaps = 62/235 (26%) Query: 169 AGFSVRNGPGPPARLPPAP----PGPLLRPARP----------------PRPYFPRPRTP 208 AG GPG A P P GPL+ PA P PRP P P P Sbjct: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAP-PP 176 Query: 209 PTCEPPSRKLPPPLPLC---RSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTR 265 PT PP LPPPLP ++ V P P + L V+ PP+ CA P P T Sbjct: 177 PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP--CAPPPPPPPPPPTP 234 Query: 266 SAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPS 325 L P+S + S++ P A P+P P +P Sbjct: 235 PP--------------LPPAS--------VLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY 272 Query: 326 PQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALTRFPASLSLPDL 380 P L+A A A + P P P P L PYA ASL P L Sbjct: 273 PG-----------LKAEPASPAQDAQEP---PAPPPPLPPYASCSPRASLPAPPL 313 Score = 40.0 bits (92), Expect = 0.004 Identities = 58/194 (29%), Positives = 68/194 (35%), Gaps = 20/194 (10%) Query: 177 PGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPS--RKLPPPLPLCRSRWVLAPP 234 P PP PP PP P A PP P P PP S R+ P + R L Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPP----PPPSAPPVSTDTSSLRRADP-----KGRSALLAD 52 Query: 235 PPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHA 294 RLR +T + R A P+ S + + S G T TL A G Sbjct: 53 IQQGTRLRKVT-QINDRSA-PQIESSKGTNKEGGGSANTRGASTPPTL--GDLFAGGFPV 108 Query: 295 LSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAV--RQPRLLRAALARGAPRGRT 352 L Q P R PS P LP+ G + PRL + A GA R Sbjct: 109 LRPAGQRDVAGGKTGQGPGSRAPS--PRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166 Query: 353 PSPR-PGPAPALQP 365 P P P P P P Sbjct: 167 PRPNVPAPPPPTPP 180 >gi|7706469 Kruppel-like factor [Homo sapiens] Length = 355 Score = 58.5 bits (140), Expect = 1e-08 Identities = 60/184 (32%), Positives = 71/184 (38%), Gaps = 18/184 (9%) Query: 124 GRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPG----P 179 GR A PGR ++ EP G G G R E G S GPG P Sbjct: 110 GRFLLAPPGRLVKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPP 169 Query: 180 PARLPP-APPGPLLRPARPPRPYFPRPRTPPTCEPPSRKL--PPPLP---------LCRS 227 P PP +P GP PA PR FP P P P L PP P + Sbjct: 170 PPDTPPLSPDGPARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDAAAAA 229 Query: 228 RWVLAPPPPVRPRLRVLTPPLALRCALPERGSRT-PSTRSAVLSGRVAGLGTELTLTPSS 286 + PP R L PL L A P+RG R+ P R+A + AG G T + S Sbjct: 230 AALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKS-SH 288 Query: 287 RRAH 290 +AH Sbjct: 289 LKAH 292 Score = 35.8 bits (81), Expect = 0.070 Identities = 56/195 (28%), Positives = 61/195 (31%), Gaps = 58/195 (29%) Query: 175 NGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPP-----SRKLPPPL-----PL 224 +G G A P PP P PP Y+P P PP P S L P L P Sbjct: 54 DGLGAEAAPEPPPPPP------PPAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPA 107 Query: 225 CRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTP 284 R++LAPP RL PP A + G G G LT Sbjct: 108 LHGRFLLAPP----GRLVKAEPPEA------DGG---------------GGYGCAPGLT- 141 Query: 285 SSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALA 344 G L E P A C P RPP P P G A L Sbjct: 142 -----RGPRGLKREGAPGPA-ASCMRGPGGRPPP-PPDTPPLSPDGP---------ARLP 185 Query: 345 RGAPRGRTPSPRPGP 359 PR P P GP Sbjct: 186 APGPRASFPPPFGGP 200 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 58.2 bits (139), Expect = 1e-08 Identities = 101/405 (24%), Positives = 143/405 (35%), Gaps = 58/405 (14%) Query: 30 ALPPDRSPTPRSRVSPGVTSLAVGPG---NPTRCQRSGVPYEGPGAPGGQQLRKSRARLP 86 A P ++PTP++ P T+ PG +P + P P A Q + LP Sbjct: 644 AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQD--SLQMFLP 701 Query: 87 RTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTP-PGR 145 + R + + G PA P PA A +GA G + +P P Sbjct: 702 QERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGLGPQAPDSQASPAPAP 760 Query: 146 SGPSGGVRSGAGHRAAAA-EHQLGAGFSVR----NGPGPPARLPPAPPGPLLRPARPPRP 200 P+ G G ++ + HQ G S + PP+R P P P+ PP Sbjct: 761 QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH 820 Query: 201 YFPRPRTPPTCE-----PPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALP 255 P P+ PPT +PPP P PP+RP+ + PL LP Sbjct: 821 PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLP 880 Query: 256 ERGSRTPSTRSAVLSGRV-AGLGTELTLT-PSSRRAHGSHALSSERQAAPTRAFCSADPL 313 + + S+ S R+ A ++ L P S+ H S P A A P Sbjct: 881 PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPA---APPP 937 Query: 314 PRPPSF------VPSLPSPQA--------------QGQAVRQPRLLRAALARG------- 346 P P +F P+LP P+A Q +A P + + + G Sbjct: 938 PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAA 997 Query: 347 -------APRGRTPSPRPGPAPALQPYALTRFPASLSLPDLVFTS 384 AP G +P PAPA P A T P L + F S Sbjct: 998 SVLVSGQAPSGTPTAPSHAPAPA--PMAATGLPPLLPAENKAFAS 1040 Score = 50.1 bits (118), Expect = 4e-06 Identities = 64/228 (28%), Positives = 89/228 (39%), Gaps = 36/228 (15%) Query: 161 AAAEHQLGAGFSVRNGP-GPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLP 219 AAA + +V+ P PPA P P G A+ P P+ TP PP P Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP----PQAPTPQAAAPPQATTP 664 Query: 220 PPLPLCRS---RWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTP--------STRSAV 268 P P S + VL PP P +LT +L+ LP+ S+ P S ++V Sbjct: 665 QPSPGLASSPEKIVLGQPPSATP-TAILTQD-SLQMFLPQERSQQPLSAEGPHLSVPASV 722 Query: 269 LSGRVAGLGTELTLTPSSRRAH-GSHALSSERQAAPTRAFCSADPLPRP-PSFVPSLPSP 326 + TP ++ A G A S+ AP +A PL P PS PSLP Sbjct: 723 IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQ 782 Query: 327 QAQGQAVRQPRLLRAALARGAPRGRTPSP-RPGPAPALQPYALTRFPA 373 G + P +P P RP P +P +++R P+ Sbjct: 783 APLGDSPHLP---------------SPHPTRPPSRPPSRPQSVSRPPS 815 Score = 40.4 bits (93), Expect = 0.003 Identities = 53/209 (25%), Positives = 66/209 (31%), Gaps = 51/209 (24%) Query: 114 SLGFPARA--------GQGRVQGAAPGRKLRGEPKTPPG---RSGPSGGVRSGAGHRAAA 162 SLG P A G G + +APG + P P R G +GG S RA++ Sbjct: 1207 SLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASS 1266 Query: 163 AEHQLGAGFSV-------RNGPGPPARLPPAPP------------------------GPL 191 + + S +GP P PP Sbjct: 1267 SLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTA 1326 Query: 192 LRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVL-----TP 246 L P P P P T EPP R PPP P + + PPP P + L P Sbjct: 1327 LDPVHQPPP---PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP 1383 Query: 247 PLALRCALPERGSRTPSTRSAVLSGRVAG 275 L LR E P +GR G Sbjct: 1384 RLPLRKTYRENVG-GPGAPEGTPAGRARG 1411 Score = 36.2 bits (82), Expect = 0.053 Identities = 70/281 (24%), Positives = 101/281 (35%), Gaps = 30/281 (10%) Query: 116 GFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVR--SGAGHRAAAAEHQLGAGFSV 173 GFPA A Q V P P PPG V + A+H L G + Sbjct: 413 GFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHML-PGQNQ 471 Query: 174 RNGPGPPA-RLP------PAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPL-- 224 PG PA +LP PA G + A P P ++ L PL L Sbjct: 472 FLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILT---NQNLAGPLSLGP 528 Query: 225 -------CRSRWVLAPPPPVRPRLRVLTPPLALRC-ALPERGSRTPSTRSA--VLSGRVA 274 S +L+ P + + P++L +LP + P+ +A VL G Sbjct: 529 VLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL 588 Query: 275 GLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPR-PPSFVPSLPSPQAQGQAV 333 L + ++ +AAP + P P+ PP+ LP Q QA Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPV---LTVQPAPQAPPAVSTPLPLGLQQPQA- 644 Query: 334 RQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALTRFPAS 374 +QP A P+ TP P PG A + + L + P++ Sbjct: 645 QQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685 >gi|58530845 zyxin [Homo sapiens] Length = 572 Score = 57.8 bits (138), Expect = 2e-08 Identities = 74/273 (27%), Positives = 98/273 (35%), Gaps = 51/273 (18%) Query: 103 DPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAA 162 +P PG P RA GRV G P P PP +G Sbjct: 37 NPFRPGDSEPPPAPGAQRAQMGRV-GEIPPPPPEDFPLPPPPLAGDGDD----------- 84 Query: 163 AEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPL 222 AE LG F P PP PP PL FP P PP E P Sbjct: 85 AEGALGGAFP----PPPPPIEESFPPAPL------EEEIFPSPPPPPEEEG-----GPEA 129 Query: 223 PLCRSRWVLAPPPPVRPRLRVLTPPLAL--RCALPERGSRTPSTRSAVLSGRVAGLGTEL 280 P+ PPP +PR +V + L + +L + ++ ++ V SG V Sbjct: 130 PI---------PPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYV----PPP 176 Query: 281 TLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPS--------FVPSLPSPQAQGQA 332 TP S ++ A P ++ S+ PLP+ P+ V P P+ Q Q Sbjct: 177 VATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQL 236 Query: 333 VRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365 Q + +LA PRG P+ P PAP P Sbjct: 237 HVQSQTQPVSLANTQPRG-PPASSPAPAPKFSP 268 >gi|4508047 zyxin [Homo sapiens] Length = 572 Score = 57.8 bits (138), Expect = 2e-08 Identities = 74/273 (27%), Positives = 98/273 (35%), Gaps = 51/273 (18%) Query: 103 DPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAA 162 +P PG P RA GRV G P P PP +G Sbjct: 37 NPFRPGDSEPPPAPGAQRAQMGRV-GEIPPPPPEDFPLPPPPLAGDGDD----------- 84 Query: 163 AEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPL 222 AE LG F P PP PP PL FP P PP E P Sbjct: 85 AEGALGGAFP----PPPPPIEESFPPAPL------EEEIFPSPPPPPEEEG-----GPEA 129 Query: 223 PLCRSRWVLAPPPPVRPRLRVLTPPLAL--RCALPERGSRTPSTRSAVLSGRVAGLGTEL 280 P+ PPP +PR +V + L + +L + ++ ++ V SG V Sbjct: 130 PI---------PPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYV----PPP 176 Query: 281 TLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPS--------FVPSLPSPQAQGQA 332 TP S ++ A P ++ S+ PLP+ P+ V P P+ Q Q Sbjct: 177 VATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQL 236 Query: 333 VRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365 Q + +LA PRG P+ P PAP P Sbjct: 237 HVQSQTQPVSLANTQPRG-PPASSPAPAPKFSP 268 >gi|18959210 WIRE protein [Homo sapiens] Length = 440 Score = 57.8 bits (138), Expect = 2e-08 Identities = 68/236 (28%), Positives = 84/236 (35%), Gaps = 39/236 (16%) Query: 33 PDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRAR-LPRTRQG 91 PD S P + S G+ + P P +R+ P + +R + LP T Sbjct: 157 PDLS-RPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQ 215 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPS-- 149 R G P P ++P R G A P R P P G S P+ Sbjct: 216 RLHPG----REGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNE 271 Query: 150 -----------------GGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPA------ 186 G VR A +A L + N P PPAR PP+ Sbjct: 272 SAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSL-----LSNRPPPPARDPPSRGAAPP 326 Query: 187 PPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLR 242 PP P++R P P P EPPSR PPP P SR PPPP P LR Sbjct: 327 PPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPP---SRTPAGPPPPPPPPLR 379 Score = 52.0 bits (123), Expect = 9e-07 Identities = 71/307 (23%), Positives = 104/307 (33%), Gaps = 65/307 (21%) Query: 31 LPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQ 90 +P R+ PR P V++ + P + T R+ +P + R R LP + Sbjct: 115 IPSSRAAAPR----PPVSAASGRPQDDTDSSRASLP---------ELPRMQRPSLPDLSR 161 Query: 91 GREDAGVGRRNRDPAEP-------GSLRPTSLGFPARAGQG----RVQGAAPGRKLR--- 136 + G ++ A P + PT L + + PG++L Sbjct: 162 PNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGR 221 Query: 137 -GEPKTPPGRSGPSG-GVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRP 194 G P PP + PS +R+G ++ A P PP R PP P P Sbjct: 222 EGPPAPPPVKPPPSPVNIRTGPSGQSLAP-------------PPPPYRQPPGVPNGPSSP 268 Query: 195 ARPPRPYFPRPRTPPTCEPPS--RKLPPPLPLCRSRWVLA--PPPPVRPRLRVLTPPLAL 250 P P+ + P R L PP P S +L+ PPPP R Sbjct: 269 TNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDP---------- 318 Query: 251 RCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSA 310 P RG+ P + +G + P R HGS S + P + Sbjct: 319 ----PSRGAAPPPPPPVIRNG-----ARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAG 369 Query: 311 DPLPRPP 317 P P PP Sbjct: 370 PPPPPPP 376 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 57.0 bits (136), Expect = 3e-08 Identities = 95/379 (25%), Positives = 131/379 (34%), Gaps = 99/379 (26%) Query: 32 PPDRSPTPR-SRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQ 90 PP+ PTPR + PG + + + V ++ PGG+ + + R T Sbjct: 1023 PPEGHPTPRPASPEPGRVATVL----------ASVKHKEAIGPGGEVVNRRR-----TLS 1067 Query: 91 GREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSG 150 G + R P E P G GR + P + G P + S Sbjct: 1068 GPVTGLLATARRGPGESADPGPF-----VEDGTGRQRPRGPSKGEAGVEGPPLAKVEASA 1122 Query: 151 GVRSGAGHRAAAAEHQ-------LGAGFSVRNGPGPPAR-LPPAPPGPLL---------- 192 ++ R A ++Q L +V+ P R P PP PL Sbjct: 1123 TLK----RRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVR 1178 Query: 193 -RPARPPRPYFPRPRTPPTCEPPSRKLP--PPLPLCRSRWVLAPPPPVRPRLRVLTPPLA 249 RPA P PP EPP L PPLP PPV P+ VLT P+ Sbjct: 1179 RRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPK-PVLTQPVP 1237 Query: 250 LRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCS 309 +GS TP+++ L G + P +RAHG+ S + P A Sbjct: 1238 KL-----QGSPTPTSKKVPLPGPGS---------PEVKRAHGTPPPVSPKPPPPPTA--- 1280 Query: 310 ADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALT 369 P+P V LPS A P P P+PA QP Sbjct: 1281 ----PKPVKAVAGLPSGSA-------------------------GPSPAPSPARQP---- 1307 Query: 370 RFPASLSLPDLVFTSVGSS 388 PA+L+ P S+G+S Sbjct: 1308 --PAALAKPPGTPPSLGAS 1324 Score = 40.4 bits (93), Expect = 0.003 Identities = 70/246 (28%), Positives = 91/246 (36%), Gaps = 64/246 (26%) Query: 139 PKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPAR---------LPPAPP- 188 P+ PP S G +G R A+E AG P PPA LPP PP Sbjct: 1161 PEPPPPLSVYHNG--TGTVRRRPASEQ---AGPPELPPPPPPA-EPPPTDLAHLPPLPPP 1214 Query: 189 -GPLLRPARP---PRPYF--PRPRTPPTCEPPSRKLPPPLP-LCRSRWVLAPPPPVRPRL 241 G +PA+P P+P P P+ + P S+K+P P P + PPPV P+ Sbjct: 1215 EGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPK- 1273 Query: 242 RVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQA 301 PP P + VAGL PS S+ Sbjct: 1274 ----PPPPPTAPKPVKA--------------VAGL-------PSG---------SAGPSP 1299 Query: 302 APTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRL------LRAALARGAPRGRTPSP 355 AP+ A L +PP PSL + A+ + P L RAA A A P+P Sbjct: 1300 APSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359 Query: 356 RPGPAP 361 G +P Sbjct: 1360 PEGASP 1365 Score = 37.7 bits (86), Expect = 0.018 Identities = 61/261 (23%), Positives = 81/261 (31%), Gaps = 69/261 (26%) Query: 139 PKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPP 198 P TP + + A H +++ E LG G PP P P+ R Sbjct: 683 PPTPRATTRQDSSLGGRARHMSSSQE-LLGDG-------------PPGPSSPMSRSQEYL 728 Query: 199 RPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERG 258 P P TPP P R A PPV + R + PP P+ Sbjct: 729 LDEGPAPGTPPREARPGRH--------GHSIKRASVPPVPGKPRQVLPPGTSHFTPPQ-- 778 Query: 259 SRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPS 318 TP+ R AL AP A P PP+ Sbjct: 779 ------------------------TPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPT 814 Query: 319 FVPSLP-----SPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPAL---------- 363 P P SP +G A P+ + + AP G P P P P L Sbjct: 815 ERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAP-GPAPPPVPTAVPTLCLPPEADAEP 873 Query: 364 -----QPYALTRFPASLSLPD 379 + ++L R+ AS S P+ Sbjct: 874 GRPKKRAHSLNRYAASDSEPE 894 Score = 35.4 bits (80), Expect = 0.091 Identities = 36/134 (26%), Positives = 46/134 (34%), Gaps = 15/134 (11%) Query: 104 PAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAA 163 P GS PTS P A G PK PP + P V++ AG + +A Sbjct: 1237 PKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP-VKAVAGLPSGSA 1295 Query: 164 EHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLP--PP 221 GP P PP L +P P P PP+ P+ +P PP Sbjct: 1296 ------------GPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPP 1343 Query: 222 LPLCRSRWVLAPPP 235 + A PP Sbjct: 1344 RAAAAAAAAAAAPP 1357 Score = 31.2 bits (69), Expect = 1.7 Identities = 85/367 (23%), Positives = 119/367 (32%), Gaps = 92/367 (25%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 PP PTP SP +T+ + GP A G K + LP T + Sbjct: 634 PPPPEPTPADCQSPKMTTFQ----DSELSDELQAAMTGP-AEVGPTTEKPSSHLPPTPRA 688 Query: 92 --REDAGVGRRNRDPAEPGSLR---PTSLGFPARAGQGRV--QGAAPGRKLRGEPKTPPG 144 R+D+ +G R R + L P P Q + +G APG TPP Sbjct: 689 TTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPG--------TPPR 740 Query: 145 RSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPP-RPYFP 203 + P H G S++ A +PP P P R PP +F Sbjct: 741 EARPG--------------RH----GHSIKR-----ASVPPVPGKP--RQVLPPGTSHFT 775 Query: 204 RPRTPPTCEP--------------------PSRKLPPPLPLCRSRWVLAPPPPVRPRLRV 243 P+TP P P+ +L PP S L P R V Sbjct: 776 PPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYV 835 Query: 244 LTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAP 303 L P+ G P +AV L L P + G +++A Sbjct: 836 LPQPVEGEVGPAAPGPAPPPVPTAV---------PTLCLPPEADAEPG----RPKKRAHS 882 Query: 304 TRAFCSADPLP-RPPSFVPSLPSPQA-------QGQAVRQP-----RLLRAALARGAPRG 350 + ++D P R VP+ P A + +VR P + R+ PR Sbjct: 883 LNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRK 942 Query: 351 RTPSPRP 357 + P P P Sbjct: 943 KGPPPPP 949 >gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo sapiens] Length = 538 Score = 57.0 bits (136), Expect = 3e-08 Identities = 107/362 (29%), Positives = 136/362 (37%), Gaps = 87/362 (24%) Query: 72 APGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGF---PARAGQGRVQG 128 AP ++ R S A++ R AG GR PGS R LG PARA R Sbjct: 97 APAPRRQRASSAQVRAARPAGMAAGTGRSG-----PGSAR-LGLGSGWDPARAVAPRAAR 150 Query: 129 AAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAA------EHQLGAGFS-VRNGPGPP- 180 A G L G SGP +R GA AAA Q G + + GPGP Sbjct: 151 AL-GAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRR 209 Query: 181 -ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRP 239 L APPG L P P P++ PR PP PP L P R R + +RP Sbjct: 210 GGGLTSAPPG--LPPLASPPPFWELPRPPPPPPPPGPALLPR----RLRELRGKEVGLRP 263 Query: 240 RLR-----VLTPPLALRCALPERGSRTPSTR--------SAVLSGR--------VAGLGT 278 R R V++P L RGSR SA+L+ AGLG Sbjct: 264 RTRGWTTCVVSPNL-------RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 316 Query: 279 E--LTLTPSSRRAHGSH-----ALSSERQAAPTRAFCSADPL--PRPPSFVPSLPSPQAQ 329 + + TP +GS LS ER + AF + L P P S+P+P + Sbjct: 317 QGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGR 376 Query: 330 ------------------------GQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365 G+ R+ AAL +GAPR + P+ P +P P Sbjct: 377 GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA-SPAASPCQAP 435 Query: 366 YA 367 A Sbjct: 436 RA 437 >gi|60460889 Myb protein P42POP [Homo sapiens] Length = 399 Score = 57.0 bits (136), Expect = 3e-08 Identities = 88/363 (24%), Positives = 131/363 (36%), Gaps = 55/363 (15%) Query: 26 EVLGALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARL 85 ++ GA S R RV G+ + G T +R+G + ++ ++ AR+ Sbjct: 38 QLYGAQSRRVSVAERRRVWDGIAAKINGI---TSWKRTGQEVQKRWNDFKRRTKEKLARV 94 Query: 86 PRTRQGREDAGVGRRNRDP-----------AEPGSLRPTSLGFPARAGQGRVQGAAPGRK 134 P + QG A + + A PG+ A + Q A P R Sbjct: 95 PHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRY 154 Query: 135 LRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRP 194 + E + R+ S ++G+ ++ E + + G P + +PP L+P Sbjct: 155 VLSEDRREDRRADTSAHSKAGS----SSPEPWARPSCTPQEGGCPRPKERESPPPSALQP 210 Query: 195 ARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCR-SRWVLAPPPPVRPRLRVLTPPLALRCA 253 + PR P PP+ LPPP PL + + +PPPP RP Sbjct: 211 VQLPRLALSPP-------PPAPPLPPPPPLAQVAPSPPSPPPPPRPP------------- 250 Query: 254 LPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPL 313 P + PS A EL T A S ALS+ P S P Sbjct: 251 -PTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPP 309 Query: 314 -----PRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGA----------PRGRTPSPRPG 358 P PP P LP P + + +P + AA+ GA PR +PRP Sbjct: 310 LPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPP 369 Query: 359 PAP 361 PAP Sbjct: 370 PAP 372 Score = 29.6 bits (65), Expect = 5.0 Identities = 43/158 (27%), Positives = 52/158 (32%), Gaps = 45/158 (28%) Query: 212 EPPSR--KLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVL 269 EPP+ PPP C R+VL+ R A A + GS +P Sbjct: 135 EPPAAPSSQPPPPSACPQRYVLSEDRREDRR--------ADTSAHSKAGSSSP------- 179 Query: 270 SGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPR----PPSFVPSLPS 325 E PS G ER++ P A LPR PP P LP Sbjct: 180 ---------EPWARPSCTPQEGGCPRPKERESPPPSALQPVQ-LPRLALSPPPPAPPLPP 229 Query: 326 PQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPAL 363 P LA+ AP +P P P P P L Sbjct: 230 PPP--------------LAQVAPSPPSPPPPPRPPPTL 253 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 57.0 bits (136), Expect = 3e-08 Identities = 70/233 (30%), Positives = 86/233 (36%), Gaps = 53/233 (22%) Query: 145 RSGPSGGV--RSGAGHRAAAAEHQL---GAGFSVRNGP-----GPPARLPPAPPGPLLRP 194 R G GG R G G R + + G G + GP G PP PP P + Sbjct: 9 RGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQ 68 Query: 195 ARPPRPYFPRPRTPPTCEPP------SRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPL 248 + P P P P+ PP +PP ++ PPP P S+ V+A P P Sbjct: 69 QQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP--------- 119 Query: 249 ALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFC 308 + A P S P+T SG G G T TP A T A Sbjct: 120 GVGSAPPASSSAPPATPPT--SGAPPGSGPGPTPTP---------------PPAVTSAPP 162 Query: 309 SADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAP 361 A P P S VP+ P PQA G P AA+ G P P+ GP P Sbjct: 163 GAPPPTPPSSGVPTTP-PQAGG-----PPPPPAAVP-----GPGPGPKQGPGP 204 Score = 33.1 bits (74), Expect = 0.45 Identities = 51/198 (25%), Positives = 62/198 (31%), Gaps = 48/198 (24%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPG-APGGQQLRKSRARLPRTRQ 90 PP + P P P P + V +GPG APG + + P Sbjct: 77 PPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP---- 132 Query: 91 GREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQG-------RVQGAAPGRKLRGEPKTPP 143 PA P PTS G P +G G V A PG P TPP Sbjct: 133 -------------PATP----PTS-GAPPGSGPGPTPTPPPAVTSAPPG----APPPTPP 170 Query: 144 GRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFP 203 P+ ++G AA GPGP + P P G P P P Sbjct: 171 SSGVPTTPPQAGGPPPPPAAV----------PGPGPGPKQGPGPGG----PKGGKMPGGP 216 Query: 204 RPRTPPTCEPPSRKLPPP 221 +P P P PP Sbjct: 217 KPGGGPGLSTPGGHPKPP 234 Score = 32.0 bits (71), Expect = 1.0 Identities = 53/216 (24%), Positives = 61/216 (28%), Gaps = 69/216 (31%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 PP P P P VTS G PT SGVP P A G Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTP-PSSGVPTTPPQAGG----------------- 183 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGG 151 P P + V G PG PK PG GP GG Sbjct: 184 -----------PPPPPAA----------------VPGPGPG------PKQGPGPGGPKGG 210 Query: 152 VRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTC 211 G + G GP P P P R PR R PP Sbjct: 211 KMPG----------------GPKPGGGPGLSTPGGHPKPPHRGGGEPRG--GRQHHPPYH 252 Query: 212 EPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPP 247 + + PP P RS ++ + L +L P Sbjct: 253 QQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRP 288 >gi|117938768 GNAS complex locus alex [Homo sapiens] Length = 626 Score = 56.6 bits (135), Expect = 4e-08 Identities = 93/366 (25%), Positives = 126/366 (34%), Gaps = 71/366 (19%) Query: 30 ALPPDRSPTPRSRVSPGVTSLAVGPGNPT--------RCQRSGVPYEGPGAPGGQQLRKS 81 A P RSP PRSR++ P T R RS P QLR+ Sbjct: 236 AAPGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRK 295 Query: 82 RARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKT 141 + R R + R DP PG + L PG+ L+ +P Sbjct: 296 QQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPL---------------PGQPLQPQPIL 340 Query: 142 PPGRSG--PSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLP--PAPPGPLLRPARP 197 PG+ P+ G +HQ + G P P P PP P+ P RP Sbjct: 341 TPGQPQKIPTPG------------QHQP----ILTPGHSQPIPTPGQPLPPQPIPTPGRP 384 Query: 198 ----PRPYFPRPRTPPTCEPPSR--KLPPPLPLCRSRWVLAP----------PPPVRPRL 241 P P RP TP + P R +LPPPL L R ++P P P+ P Sbjct: 385 LTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQPLLPPG 444 Query: 242 RVLTPPLALRCALPERGSRT----PSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSS 297 + + L+ P +R+ P+ RS + + GL L S R A + + Sbjct: 445 QPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRGLLARLPGGASPRAAAAAACTTM 504 Query: 298 ERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRG------R 351 + A T P PP S + A P +A P G R Sbjct: 505 KGWPAATMTPAETSPTMGPPD--ASAGFSIGEIAAAESPSATYSATFSCKPSGAASVDLR 562 Query: 352 TPSPRP 357 PSP+P Sbjct: 563 VPSPKP 568 Score = 38.5 bits (88), Expect = 0.011 Identities = 48/163 (29%), Positives = 62/163 (38%), Gaps = 14/163 (8%) Query: 224 LCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLT 283 L + VL P + PR P L+ PE + P R LS LGT Sbjct: 122 LLQEAQVLQGSPELLPRS---PKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPR 178 Query: 284 PSSRRAHGSHALSSERQAAPTRAFCSADPLPRPP--SFVPSLPSPQAQGQAVRQPRLLRA 341 +H S A +S RQ+ P S P R P S PS P+ R LL Sbjct: 179 GFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPK------RLSDLLLT 232 Query: 342 ALARGAPRGRTPSPRPGPAPALQPYALTRFPASLSLPDLVFTS 384 + A AP R+P PR A P T P++ + P T+ Sbjct: 233 SRA-AAPGWRSPDPR--SRLAAPPLGSTTLPSTWTAPQSRLTA 272 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 56.6 bits (135), Expect = 4e-08 Identities = 80/272 (29%), Positives = 97/272 (35%), Gaps = 37/272 (13%) Query: 139 PKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPG--PLLRPAR 196 P +PP S A A H L A FS P PP + P +PP P+ A Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSPPASPPVSPSAT 690 Query: 197 PPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPE 256 PP P PP PPS PP+ + APPP P L+V P A + P Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA---SPPM 747 Query: 257 RGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSS-ERQAAPTRAFCSADPLPR 315 S TP R L L + PS + L+ QA P A LP Sbjct: 748 SPSATPPPRVPPLLA-----APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Query: 316 PPSFVP---------SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPY 366 PP+ P SLP + P +L A L + P P +P LQ Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ-------VPPSPPASPTLQAP 855 Query: 367 ALTRFPASLSLPDLVFTSV-GSSLVICLVPTP 397 P PD TSV G L + L P P Sbjct: 856 RRPPTPG----PD---TSVSGPRLTLALAPGP 880 Score = 52.0 bits (123), Expect = 9e-07 Identities = 97/401 (24%), Positives = 128/401 (31%), Gaps = 82/401 (20%) Query: 33 PDRSPTPRSRVSPG---VTSLAVGPGNPTRCQRSG----------VPYEGPGAPGGQQLR 79 P SP P V+P V A G +R+G P GP G R Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88 Query: 80 KSRARLPRTRQGREDAGVGRRNRDP---AEPGSLRPTSLGFPARAGQGRVQGAAPGRKLR 136 +R P + GR + +N P + PG T+ P GQ ++ +A R Sbjct: 89 NPASRPPAS--GRGERAPPAKNTSPGPVSSPGRASGTTR--PGPLGQKGLRISAEETVAR 144 Query: 137 GEPKTPPGRSGPSGGVR------------SGAGHRAAAAEHQLG---------------- 168 G+ P RS S G R R+ AA ++G Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204 Query: 169 -------AGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPP 221 A P P AR P+ G L RPA P + P PS + P Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264 Query: 222 LPLCRSRWVLAPPPPVRPR-LRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTEL 280 P A P +P+ L+ L PP P R P+ + L + Sbjct: 265 AP--------AHPSQPKPKGLQALRPPQ----VTPPRKDAAPA---------LGPLSSSP 303 Query: 281 TLTPSSRRAHGSHALSSERQAAPTRA-FCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLL 339 TPS + A P A + PL P P PS Q + P Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP--- 360 Query: 340 RAALARGAPRGRTPSPRPGPAPALQPYALTRFPASLSLPDL 380 A AP T P P P+LQ + P SL+ P L Sbjct: 361 PATPPSQAPPSMTTPPMQAP-PSLQTIPPIQVPHSLTSPSL 400 Score = 50.8 bits (120), Expect = 2e-06 Identities = 64/218 (29%), Positives = 79/218 (36%), Gaps = 54/218 (24%) Query: 177 PGPPARLP------PAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWV 230 P PPA P P+ P+ A PP P+ PP P ++PP P + Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVPPSPPASPTLQA 854 Query: 231 LAPPPPVRPRLRVLTPPLALRCA--LPERGSRTPSTRSAVLSG-RVAGLGTELTLTPSSR 287 PP P V P L L A P SR+P S+ LSG +AG + T TP Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEEL 911 Query: 288 RAHGS-------------------HALSSERQAAPTRAFCSAD--PLPRPPSFVPSLPSP 326 R + S H + R AP AF A PLP PP+ P Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG---- 967 Query: 327 QAQGQAVRQPRLLRAALARGAPRGRTPSP---RPGPAP 361 A G L P TP+P PGP+P Sbjct: 968 SADG--------LCTIYETEGPESATPAPGALDPGPSP 997 Score = 48.9 bits (115), Expect = 8e-06 Identities = 86/330 (26%), Positives = 108/330 (32%), Gaps = 25/330 (7%) Query: 70 PGAPGGQQLRKSRAR-----LPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPAR---- 120 PG P R+SRA LPR R S T+ PA Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228 Query: 121 -AGQGRVQGAAPGRKLRGEPKTPPGRSGPSG-GVRSGAGHRAAAAEHQLGAGFSVRNGPG 178 AG G + A+ P + P RSGPS G H + L A +R Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA---LRPPQV 285 Query: 179 PPARLPPAPP-GPLLR-PARPPRPYFP--RPRTPP--TCEPPSRKLPPPLPLCRSRWVLA 232 P R AP GPL P P P RP PP P LPP PL + Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345 Query: 233 PPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGS 292 P P P L+ L P A + TP ++ + + +LT S +A S Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405 Query: 293 HALSSERQA-----APTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGA 347 S QA +PT + P SL SP L+A L+ A Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465 Query: 348 PRGRTPSPRPGPAPALQPYALTRFPASLSL 377 S P +P P + A SL Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495 Score = 44.7 bits (104), Expect = 2e-04 Identities = 62/209 (29%), Positives = 75/209 (35%), Gaps = 42/209 (20%) Query: 179 PPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVR 238 PPA L P L A PP P T P E P P P PL L PPP Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP--PCPAPCPLQAPPSPLTTPPPET 583 Query: 239 PRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSE 298 P + TPP P A+ S + GL + L+P + + Sbjct: 584 PS-SIATPP--------------PQAPPALASPPLQGLPSP-PLSPLA---------TPP 618 Query: 299 RQAAPTRAFCSADPLPRPPSFVP----SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPS 354 QA P A P PP+ P + PSPQA P L L + AP PS Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-------PNALAVHLLQ-APFSPPPS 670 Query: 355 P---RPGPAPALQPYALTRFPASLSLPDL 380 P P PA P + + P S + P L Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSL 699 Score = 44.7 bits (104), Expect = 2e-04 Identities = 66/218 (30%), Positives = 80/218 (36%), Gaps = 26/218 (11%) Query: 177 PGPPARLP-PAPPGPLLRPA--RPPRPYFPRPRTPPT-CEPPSRKLPPPLPLCRSRWVLA 232 P PA P APP PL P P P P+ PP PP + LP P PL LA Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLS----PLA 615 Query: 233 PPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVA-GLGTELTLTPSSRRAHG 291 PPP P L PPL A P + P + A S + L L P S Sbjct: 616 TPPPQAPPXLAL-PPLQ---APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671 Query: 292 SHALSSERQAAPTRAFCSADPLPRPPSFV-------PSLPSPQAQGQAVRQPRLLRAALA 344 A+P + + P PPS PS P+ + P LA Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731 Query: 345 RGAPRGRTPSPRPGPAPALQPYAL--TRFPASLSLPDL 380 AP + P P P +P + P A R P L+ P L Sbjct: 732 --APPLQVP-PSPPASPPMSPSATPPPRVPPLLAAPPL 766 Score = 39.3 bits (90), Expect = 0.006 Identities = 64/229 (27%), Positives = 74/229 (32%), Gaps = 51/229 (22%) Query: 177 PGPPARLPPAPPGPLLRP--------ARPPRPYFPRP-----RTPPTCEPPSRKLPPPLP 223 P P PP P + P A PP P P TPP PP LPP Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP--- 629 Query: 224 LCRSRWVLAPP-PPVRPRLRVLTPP-------LALRCALPERGSRTPSTRSAVLSGRVAG 275 + APP PP P L L P LA+ L S PS A Sbjct: 630 ------LQAPPSPPASPPLSPLATPSPQAPNALAVH-LLQAPFSPPPSPPVQAPFSPPAS 682 Query: 276 LGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPS----PQAQGQ 331 + TP S QA P+ A P PP+ P PS PQA Sbjct: 683 PPVSPSATPPS-------------QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729 Query: 332 AVRQPRLLRAALARGAPR--GRTPSPRPGPAPALQPYALTRFPASLSLP 378 P + + P TP PR P A P + P + SLP Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA-SLP 777 Score = 38.1 bits (87), Expect = 0.014 Identities = 70/245 (28%), Positives = 81/245 (33%), Gaps = 48/245 (19%) Query: 177 PGPPARLPPAPP---GPLLRPARPPRPYFPRPRTPPTCEP------------PSRKLPPP 221 P PA PP P PL PA PP P P P S P Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503 Query: 222 L-----PLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGL 276 L P ++ LAPP P + TPPL PS L A L Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPL----------ENLPSLAPPPLQTASAPL 553 Query: 277 GTELTLTPSSRRAHGSHALSSERQAAPTRAFCS-ADPLPRPPSFVPSLPSPQAQGQAVRQ 335 T TP A S P S A P P+ P P+L SP QG + Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP---PALASPPLQG--LPS 608 Query: 336 PRLLRAALARGAPRGRTPSPRPGPAPALQP-YALTRFPASLSLPDLVFTS--VGSSLVIC 392 P L A TP P+ P AL P A PAS L L S ++L + Sbjct: 609 PPLSPLA---------TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659 Query: 393 LVPTP 397 L+ P Sbjct: 660 LLQAP 664 Score = 37.7 bits (86), Expect = 0.018 Identities = 51/165 (30%), Positives = 68/165 (41%), Gaps = 29/165 (17%) Query: 223 PLCRSRWVLAPPPPVRPR---------LRVL-------TPPLALR------CALPERGSR 260 P R+ +L P PP PR LRVL PLA R +PE R Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 261 TPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFV 320 TRSA S R + + RA + S ++P RA + P P + Sbjct: 77 AGPTRSAGTSSR--NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 321 P-SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPG-PAPAL 363 S A+G+A P+ R+AL+ GA R T P PG P+PA+ Sbjct: 135 RISAEETVARGKATEAPK--RSALSAGARRD-TSGPTPGTPSPAM 176 Score = 32.0 bits (71), Expect = 1.0 Identities = 52/182 (28%), Positives = 62/182 (34%), Gaps = 29/182 (15%) Query: 33 PDRSPTPR--SRVSPGVTSLAVGPGNPTRCQRS-GVPYEGPGAPGGQQLRKSRARLPRTR 89 P R PTP + VS +LA+ PG P RS GP G S R Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914 Query: 90 QGREDAGVGRR---------------NRDPAEPGSLR---PTSLGFPARAGQGRVQGAAP 131 + G +R PA P + R L +P G G G Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 974 Query: 132 GRKLRG-EPKTP-PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPG 189 + G E TP PG P + G AA A GAG S R+ ARL P G Sbjct: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGA----GAGASSRS--PKQARLGELPLG 1028 Query: 190 PL 191 L Sbjct: 1029 AL 1030 Score = 29.3 bits (64), Expect = 6.5 Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 10/130 (7%) Query: 65 VPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQG 124 VP P +P Q R+ P T + P P ++L P AG Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901 Query: 125 RVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLP 184 + P +LRG SGP GG + A A A GP PP Sbjct: 902 SSATSTP-EELRGYD------SGPEGGAAASPPPDAELAACHPAAW---SRGPAPPLAFR 951 Query: 185 PAPPGPLLRP 194 AP PL P Sbjct: 952 GAPGAPLPWP 961 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 55.5 bits (132), Expect = 9e-08 Identities = 111/418 (26%), Positives = 138/418 (33%), Gaps = 121/418 (28%) Query: 29 GALPPDRS------PTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPG-------- 74 G+ PP+R P P +P T A PG+ R + P GP PG Sbjct: 296 GSAPPERQEQRHSLPHPYPYPAPAYT--AHPPGH--RLVPAAPPGPGPRPPGAESHGCLP 351 Query: 75 -----GQQLRKSRARLPRTRQGREDAGVGR-----RNRDPAEPGSLRPTSLGFPARAGQG 124 G LR+SR + R A +R P PG+ +S + G Sbjct: 352 ATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG-- 409 Query: 125 RVQGAAPGRKLRGEP--KTPP------GRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNG 176 ++G P + G +TP GR GPS A AA L Sbjct: 410 -LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLP------ 462 Query: 177 PGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTC-----------------EPPSRKLP 219 PGP + PP PP P L RPP P P P C E P R P Sbjct: 463 PGPSS--PPPPPCPRL--LRPPPP--PAWLKGPACRAAREDGEILEELFFGTEGPPRPAP 516 Query: 220 PPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTE 279 PPLP L PP A R ++ + S TP T Sbjct: 517 PPLP--HREGFLGPP--------------ASRFSVGTQDSHTPPTPPT------------ 548 Query: 280 LTLTPSSRRAHGSHALSSERQAA---PTRAFCSADPLPRPPS----------------FV 320 T SS GSH+ S + P S DPLPRPPS Sbjct: 549 -PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP 607 Query: 321 PSLPSP--QAQGQAVRQPRLLRAALARGAPRGRTPSPRPGP---APALQPYALTRFPA 373 P+ PS Q + R+P R ++ P P PGP AP P + PA Sbjct: 608 PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPA 665 Score = 44.3 bits (103), Expect = 2e-04 Identities = 74/290 (25%), Positives = 92/290 (31%), Gaps = 45/290 (15%) Query: 58 TRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGF 117 TRC S + Y G A G ++ RL + + G + P L Sbjct: 127 TRCYHSALRYGGSFAELGPRI----GRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHL 182 Query: 118 PARAGQGRVQGAAPGRKLRG----EPKTPPGRSGPSG--GVRSGAGHRAAAAEHQLGAGF 171 + G +G P ++ +P P SGPSG G+ G R Q G Sbjct: 183 EHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPP 242 Query: 172 SVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCE---------------PPSR 216 + P PP LPP PP P PP P P T P + P R Sbjct: 243 GL---PLPPPPLPPPPP-----PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPER 294 Query: 217 KLPPPLPLCRSRWVLAPPPPVRPRLRVLTPP--LALRCALPERGSRTPSTRSAVLSGRVA 274 K P R L P P PP + A P G R P S Sbjct: 295 KGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATR 354 Query: 275 GLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLP 324 G++L R S SS AA T +P PS P LP Sbjct: 355 PPGSDL----RESRVQRSRMDSSVSPAATTAC------VPYAPSRPPGLP 394 Score = 38.1 bits (87), Expect = 0.014 Identities = 74/333 (22%), Positives = 108/333 (32%), Gaps = 64/333 (19%) Query: 86 PRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTP--- 142 P ++ G + PA P S P + AR+ + +P + + P P Sbjct: 547 PTPTTSSSNSNSGSHSSSPAGPVSFPPPP--YLARSIDPLPRPPSPAQNPQDPPLVPLTL 604 Query: 143 ---PGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPP----ARLP-PAPPGPLLRP 194 P SG+ R + ++ + GPGPP ++ P P PPG P Sbjct: 605 ALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664 Query: 195 ARPPRPY-FPRPRTPPTCEPPSRKLPPPLPLCRSRWVL-----------------APPPP 236 AR PR + FP E P+ P L +L AP PP Sbjct: 665 ARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724 Query: 237 VRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALS 296 ++ L P P+ + + + T T T ++ + Sbjct: 725 LKEPFASLQSPF-------------PTDTAPTTTAPAVAVTTTTTTTTTT-------TAT 764 Query: 297 SERQAAPTRAFCSADPLPR-PPSFVPSLPSPQAQGQAVRQPRLLRAALARGAP-----RG 350 E + P A PL + PP P P P A L A++ G G Sbjct: 765 QEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSL--ASVLEGQKYCYRGTG 822 Query: 351 RTPSPRPGPAPALQ-----PYALTRFPASLSLP 378 S RPGP P Q P T P + + P Sbjct: 823 AAVSTRPGPLPTTQYSPGPPSGATALPPTSAAP 855 Score = 35.0 bits (79), Expect = 0.12 Identities = 86/392 (21%), Positives = 120/392 (30%), Gaps = 98/392 (25%) Query: 23 YTFEVLGALPPDRSPTPRSRVSPGVT-SLAVGPGNPTRC-QRSGVPYEGPGAPGGQQLRK 80 Y + LP SP + P V +LA+ P P+ C Q + + P +P + Sbjct: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP------R 629 Query: 81 SRARLPRTRQGREDAGVGRRNR--DPAEPG-----SLRPTSLGFPARAGQGRVQGAAPGR 133 R P+T + G ++ P PG + P FP + + + A + Sbjct: 630 PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFK 689 Query: 134 KLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLR 193 L P G + + +H+ G AP PL Sbjct: 690 IL------PDGLANIMKMLDESIRKEEEQQQHEAGV----------------APQPPLKE 727 Query: 194 PARPPRPYFPRPRTPPTCEP-----------------------PSRKLPPPLPLCRSRWV 230 P + FP P T P P LPPP PL + Sbjct: 728 PFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF--- 784 Query: 231 LAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAH 290 PPP +P+ P P S S S + + GT Sbjct: 785 ---PPPSQPQPPPPPP--------PSPASLLKSLASVLEGQKYCYRGT------------ 821 Query: 291 GSHALSSERQAAPTRAFCSADPLPRPPSFVPSLP----SPQAQGQAVRQPRLLRAALARG 346 A+S+ PT + P PPS +LP +P AQG G Sbjct: 822 -GAAVSTRPGPLPTTQYS-----PGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG 875 Query: 347 APRGRTPSPRPGPAPALQPYALTRFPASLSLP 378 P R R G P P T+ P LSLP Sbjct: 876 GPWAR--ERRAGEEPVPGPMTPTQPPPPLSLP 905 Score = 34.3 bits (77), Expect = 0.20 Identities = 68/259 (26%), Positives = 91/259 (35%), Gaps = 58/259 (22%) Query: 168 GAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPR--TPPTCEPPSRKLPPPLPLC 225 GA S R GP P + P PP A PP P + P+ S+ P Sbjct: 822 GAAVSTRPGPLPTTQYSPGPPSG--ATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWA 879 Query: 226 RSRW-----VLAPPPPVRPRLRVLTPPLALRCALPERGSRTPST------RSA------V 268 R R V P P +P + PP + E SR T RSA V Sbjct: 880 RERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPV 939 Query: 269 LSGRVAGLGTELTLTPSSRR--AHGSHALSS---------ERQAAPTRAFCSADPLPRP- 316 + A GTE L P+ + A G A+S +++ R C RP Sbjct: 940 DTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPR 999 Query: 317 ------PSFVP-----------SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGP 359 + VP L S + QG+ +P L A+ A+ P+P P Sbjct: 1000 EGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPP---TAPAPPSAP 1056 Query: 360 APALQPYALTRFPASLSLP 378 AP+ QP P S S+P Sbjct: 1057 APSAQP-----TPPSASVP 1070 Score = 30.8 bits (68), Expect = 2.2 Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 22/133 (16%) Query: 249 ALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFC 308 A R P + + P V ++G E L+P +R G + SE+ P Sbjct: 190 AKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCN---SEQTGLPPGLPL 246 Query: 309 SADPLPRPPSFVPSLPSP-------------------QAQGQAVRQPRLLRAALARGAPR 349 PLP PP P P P G A R A R R Sbjct: 247 PPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQR 306 Query: 350 GRTPSPRPGPAPA 362 P P P PAPA Sbjct: 307 HSLPHPYPYPAPA 319 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 55.5 bits (132), Expect = 9e-08 Identities = 64/220 (29%), Positives = 79/220 (35%), Gaps = 48/220 (21%) Query: 174 RNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCR--SRWVL 231 + G PP +PP+PP P+ A P P P P P P + PPP+P RW++ Sbjct: 668 QQGSAPPTPVPPSPPQPVTLGA-VPAPQAP-PPPPKALYPGALGRPPPMPPMNFDPRWMM 725 Query: 232 APPPPVRPRLRVLTPPLALRCALPERGSRTPSTRS---------------AVLSGR---- 272 PP V PRL PPL P RS A+L R Sbjct: 726 I-PPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPP 784 Query: 273 ----VAGLGTELTLTPSSRRAHGSHALSSERQAA---PTRAFCSADPLPRPPSFVPSLPS 325 +A +G T TP+ R S RQAA P+P PP ++ S P Sbjct: 785 VDPKLAWVGDVFTATPAEPRP----LTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840 Query: 326 PQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365 G A G P R P PGP P P Sbjct: 841 FPENG-------------APGPPISRFPLEEPGPRPLPWP 867 Score = 44.7 bits (104), Expect = 2e-04 Identities = 97/407 (23%), Positives = 123/407 (30%), Gaps = 111/407 (27%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGA------PGGQQLRKSRARL 85 PP P P PG PG P S P E PG PG ++ K + Sbjct: 826 PPVPPPPPYLASYPGFPENGA-PGPPI----SRFPLEEPGPRPLPWPPGSDEVAKIQTPP 880 Query: 86 PRTRQGREDA--------------GVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAP 131 P+ +E+ GVG + P P T + R G R +G P Sbjct: 881 PKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSR-RGIPP 939 Query: 132 GRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPL 191 EP PP R+GP P PP ++ PP PL Sbjct: 940 E-----EPGAPPRRAGPI-------------------------KKPPPPTKVEELPPKPL 969 Query: 192 LRPARPPRPYFPRPRT-------PPTCEPPSRKLPPPLPLCRS-RWVLAPPPPVRPRLR- 242 + P+P P P P PP+ L P L R + P R R R Sbjct: 970 EQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRG 1029 Query: 243 -VLTPPLALRCALPERG---------------------------SRTPSTRSAVLSGRVA 274 R RG + P+ R S Sbjct: 1030 EYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTAS-ETR 1088 Query: 275 GLGTELTLTPSSRRAHGSH----------ALSSERQAAPTRAFCSADPLPRPPSFVPSLP 324 G+E P RR GS A S + P + PL PP P P Sbjct: 1089 SEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSP 1148 Query: 325 SP---QAQGQAVRQPRLLRAALARGAPRGRTPSPRPG---PAPALQP 365 +P A+G V PR + + RG R P PG PA +L P Sbjct: 1149 APARFTARGGRVFTPRGVPSRRGRGGGR-PPPQVCPGWSPPAKSLAP 1194 Score = 39.3 bits (90), Expect = 0.006 Identities = 86/369 (23%), Positives = 123/369 (33%), Gaps = 77/369 (20%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPG--GQQLRKSRARLPRT- 88 PP+ + +P R+ + VGP + R G G G G + R +R+R R+ Sbjct: 998 PPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSY 1057 Query: 89 RQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGP 148 R+ R D G G P P PA G+ + + G + PK R Sbjct: 1058 REFRGDDGRGGGTGGPNHP----------PAPRGRTASETRSEGSEYEEIPKRRRQRGSE 1107 Query: 149 SGGVRSGAGHRAAAAEHQLGAGFSVRNGP-GPPARLPPAPPGPLLRPARPPRPYFPR--- 204 +G + + E ++ P PP P P P AR R + PR Sbjct: 1108 TGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVP 1167 Query: 205 -----------PRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCA 253 P+ P PP++ L P P P PP + L+ P Sbjct: 1168 SRRGRGGGRPPPQVCPGWSPPAKSLAPKKP------PTGPLPPSKEPLKEKLIP------ 1215 Query: 254 LPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPL 313 G +P R G + +G E P RR HG A Sbjct: 1216 ----GPLSPVARGGSNGG--SNVGMEDGERP-RRRRHG-----------------RAQQQ 1251 Query: 314 PRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQPYALTRFP- 372 +PP F + ++Q R A + G P P+ PGP AL + P Sbjct: 1252 DKPPRF-----------RRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPR 1300 Query: 373 -ASLSLPDL 380 A+ PDL Sbjct: 1301 RAAAKSPDL 1309 Score = 35.8 bits (81), Expect = 0.070 Identities = 38/151 (25%), Positives = 51/151 (33%), Gaps = 54/151 (35%) Query: 99 RRNRDPAEPGSLRPTSLGFPARAGQGRVQGAA-----------------------PGRKL 135 R +++ P L P ++G P G G V G + PG + Sbjct: 1335 RGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMER 1394 Query: 136 RGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPA 195 + P G++G SG SG G G G R GPG Sbjct: 1395 QNRRPGPGGKAGSSGS-SSGGG----------GGGPGGRTGPG----------------- 1426 Query: 196 RPPRPYFPRPRT---PPTCEPPSRKLPPPLP 223 R + +P P+ PP PP LPPP P Sbjct: 1427 RGDKRSWPSPKNRSRPPEERPPGLPLPPPPP 1457 Score = 34.3 bits (77), Expect = 0.20 Identities = 90/382 (23%), Positives = 119/382 (31%), Gaps = 85/382 (22%) Query: 29 GALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGP----GAPGGQQLRKSRAR 84 G P PTP++ + PG P P+ GP G PG R Sbjct: 378 GNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPC 437 Query: 85 LPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQG---------------- 128 P + ++A RR + +E SL + R+Q Sbjct: 438 KPPAPEDEDEAWRQRRKQSSSEI-SLAVERARRRREEEERRMQEERRAACAEKLKRLDEK 496 Query: 129 -AAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAP 187 AP ++L+ EP PP + PS A + P PPA P + Sbjct: 497 FGAPDKRLKAEPAAPP--AAPSTPAPPPAVPKEL---------------PAPPAPPPASA 539 Query: 188 PGPLLRPARPPR-PYFPRPRTPPTCEPP---------------SRKLPPPLPLCRSRWVL 231 P P P P + P TP P S + P P S+ Sbjct: 540 PTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGP 599 Query: 232 APPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHG 291 PP V P TPP+ + +G TR G + + +L P +R Sbjct: 600 EPPEEVPP---PTTPPVP---KVEPKGDGIGPTRQPPSQG-LGYPKYQKSLPPRFQRQQQ 652 Query: 292 SHALSSERQAA-PTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRG 350 L ++Q SA P P PPS QP L A A AP Sbjct: 653 EQLLKQQQQHQWQQHQQGSAPPTPVPPS--------------PPQPVTLGAVPAPQAP-- 696 Query: 351 RTPSPRPGPAPALQPYALTRFP 372 P P AL P AL R P Sbjct: 697 ------PPPPKALYPGALGRPP 712 Score = 33.9 bits (76), Expect = 0.27 Identities = 64/268 (23%), Positives = 83/268 (30%), Gaps = 38/268 (14%) Query: 96 GVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGR---------KLRGEP--KTPPG 144 G+ R+NR P PG +S G G PGR K R P + PPG Sbjct: 1391 GMERQNRRPG-PGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPG 1449 Query: 145 RSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPG--PLLRPARPPRPYF 202 P S A R H AG + PG P +P P P Sbjct: 1450 LPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQG 1509 Query: 203 PRPRTPPTCEP----------PSRKLPPPL-----PLCRSRWVLAPPPPVRPRLRVLTPP 247 P PR P EP P + P P+ R ++P PP R P Sbjct: 1510 PSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPE 1569 Query: 248 LALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAF 307 L +LP P S L + G G + + A H + A +++ Sbjct: 1570 LLQEESLP------PPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSY 1623 Query: 308 CSADPLPRPPSFVPSLPSPQAQGQAVRQ 335 P P P P G + Q Sbjct: 1624 ---RPSSMEPWMEPLSPFEDVAGTEMSQ 1648 Score = 33.5 bits (75), Expect = 0.35 Identities = 94/375 (25%), Positives = 120/375 (32%), Gaps = 89/375 (23%) Query: 28 LGALP-PDRSPTPRSRVSPGVTSLA--VGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRAR 84 LGA+P P P P + PG + P N PY P +L + R Sbjct: 687 LGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDP------RLLQGRPP 740 Query: 85 LPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAP--------GRKLR 136 L G +G+ R R + S P PA R +G P G Sbjct: 741 LDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAML---RERGTPPVDPKLAWVGDVFT 797 Query: 137 GEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARL------------- 183 P P + P R AA E G P PP L Sbjct: 798 ATPAEPRPLTSPL---------RQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPG 848 Query: 184 PPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPRLRV 243 PP PL P P P+ P + P K PP + + P +P V Sbjct: 849 PPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKE--ETAQLTGPEAGRKPARGV 906 Query: 244 LT-----PPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSE 298 + PP P R SRT TR G SSRR + E Sbjct: 907 GSGGQGPPP-------PRRESRT-ETRWGPRPG-------------SSRR-----GIPPE 940 Query: 299 RQAAPTRAFCSADPL--PRPPSFVPSL-PSPQAQGQAVRQP------RLLRAALARGAPR 349 AP R A P+ P PP+ V L P P QG +P ++ + L G P+ Sbjct: 941 EPGAPPR---RAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKL--GGPK 995 Query: 350 GRTPSPRPGPAPALQ 364 P+ PAP L+ Sbjct: 996 ETPPNGNLSPAPRLR 1010 Score = 32.3 bits (72), Expect = 0.77 Identities = 61/218 (27%), Positives = 72/218 (33%), Gaps = 47/218 (21%) Query: 30 ALPPDRSPTPRSRVSPGVTSLAVGPGNP--TRCQRSGVPY-------EGPGAPGGQQL-- 78 A PP+ P P S+ +P P P T SGV G GG+ Sbjct: 103 AQPPESQPLPASQ-TPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSL 161 Query: 79 --RKSRARLPRTRQGREDAGVGRRNRDPAE----PG-SLRP-TSLGFPARAGQGRVQGAA 130 R SR P T Q D + R+ AE PG SLRP S + G+G + Sbjct: 162 LSRFSREEFP-TLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEG 220 Query: 131 PGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPP----- 185 P KL P G PSG + F G PP PP Sbjct: 221 PDSKLH-HGHDPRGGLQPSGPPQ-----------------FPPYRGMMPPFMYPPYLPFP 262 Query: 186 ---APPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPP 220 P GP P FPR P PP R + P Sbjct: 263 PPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEP 300 Score = 32.3 bits (72), Expect = 0.77 Identities = 47/205 (22%), Positives = 66/205 (32%), Gaps = 32/205 (15%) Query: 180 PARLPPAPPGPLLRPARPPR----PYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPP 235 P PP P +RPP P P+P PP P+ PP + P Sbjct: 381 PNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPP-----GDYPDRGGP 435 Query: 236 PVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHAL 295 P +P P A +R ++ S S + E RRA + L Sbjct: 436 PCKP-----PAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKL 490 Query: 296 S--SERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTP 353 E+ AP + + P P PS P+P A+ + P P Sbjct: 491 KRLDEKFGAPDKRLKAE---PAAPPAAPSTPAPPP-------------AVPKELPAPPAP 534 Query: 354 SPRPGPAPALQPYALTRFPASLSLP 378 P P P +P + P + S P Sbjct: 535 PPASAPTPETEPEEPAQAPPAQSTP 559 Score = 31.6 bits (70), Expect = 1.3 Identities = 79/347 (22%), Positives = 107/347 (30%), Gaps = 59/347 (17%) Query: 36 SPTPRSRVSPGVTSLAVGPGN--PTRCQ----RSGVPYEGPGAPGGQQLRKSRARLPRTR 89 +P R PG+ GP PTR + SG+ + G +R PR Sbjct: 1492 APGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVR-GVGGTPRDS 1550 Query: 90 QGREDAGVGRRNRDPAEPGSLRPTSLGFPARAG--QGRVQGAAPGRKLRG---------- 137 G RR R P +P L+ SL P +G + +G P + R Sbjct: 1551 AGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHI 1610 Query: 138 -------------EPKTPPGRSGPSGGVRSGAGHRAAAAEH--QLGAGFSVRNGP----- 177 P + P AG + ++ L V +GP Sbjct: 1611 WNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRS 1670 Query: 178 GPPARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPV 237 P L A GP RP PP EPP R PPP P R L P+ Sbjct: 1671 SPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRR--PPPAPHDGDRKELPREQPL 1728 Query: 238 RPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGT-----ELTLTPSSRRAHGS 292 P P R +RG+ R + G GT +L L Sbjct: 1729 PP-----GPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEK 1783 Query: 293 HALSSERQAAPT--------RAFCSADPLPRPPSFVPSLPSPQAQGQ 331 +S +A P A SA+P + +P P + GQ Sbjct: 1784 ELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQ 1830 Score = 29.6 bits (65), Expect = 5.0 Identities = 48/153 (31%), Positives = 58/153 (37%), Gaps = 22/153 (14%) Query: 141 TPPGRSGPSGGVRSGAGHRAAA---AEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARP 197 TP G SG + SGA + + QL V G PPA P PP LL Sbjct: 1959 TPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPV---VNFGSLPPAPPPAPPPLSLLPVGPA 2015 Query: 198 PRPYFPRPRTPPTCEPPSRKLPP---PLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCAL 254 +P R PP P +R LP P P R L P L+ L L Sbjct: 2016 LQPPSLAVRPPPA--PATRVLPSPARPFPASLGRAELHP-----VELKPFQDYQKLSSNL 2068 Query: 255 PERG-SRTPSTRSAVLSGRVAGLGTELTLTPSS 286 G SRTP T + +GL + L TPS+ Sbjct: 2069 GGPGSSRTPPTGRS-----FSGLNSRLKATPST 2096 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 55.1 bits (131), Expect = 1e-07 Identities = 93/397 (23%), Positives = 134/397 (33%), Gaps = 84/397 (21%) Query: 40 RSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRT-RQGREDAGVG 98 R R SPG S + G + +++ ++ R A P+ +QGR + Sbjct: 30 RGRASPGGVSTSSSDGKAEKSRQTA-----------KKARVEEASTPKVNKQGRSEEISE 78 Query: 99 RRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGH 158 + + P + T P + + GR L + + P S + + Sbjct: 79 SESEETNAPKKTK-TEQELPRPQSPSDLD-SLDGRSLNDDGSSDPRDIDQDNRSTSPSIY 136 Query: 159 RAAAAEHQLGAGFSVRNGPG----PPARLPPAPPGPLLRPARPPRPYFPRPRTPPT---- 210 + E+ + + GP PP PP+P P P +P + P P PT Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196 Query: 211 -CEPPSRKLPPPLPLCRSRWVLAPP--PPVRPRL------RVLT-PPL-------ALRCA 253 EPP+ SR APP PP P+L VL+ PP+ A Sbjct: 197 PMEPPT-----------SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG 245 Query: 254 LPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADP- 312 P G + P + + G T P++ G+ A P F P Sbjct: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLP-----SAPPPANFPHVTPN 300 Query: 313 LPRPPSFVP------------------SLPSPQAQGQAVRQPRLLRAALARGAPRGRTPS 354 LP PP+ P LPSP A GQ + L G +G T + Sbjct: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGM-------GGLPPGPEKGPTLA 353 Query: 355 PRP---GPAPALQPYALTRFPASLSLPDLVFTSVGSS 388 P P PA + P RFP S S S SS Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390 Score = 46.2 bits (108), Expect = 5e-05 Identities = 89/344 (25%), Positives = 120/344 (34%), Gaps = 48/344 (13%) Query: 32 PPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQG 91 P SP S + L+ GP P + P P Q S R P Sbjct: 133 PSIYSPGSVENDSDSSSGLSQGPARPY--------HPPPLFPPSPQPPDSTPRQPEASFE 184 Query: 92 REDAGVGRRNRDPAEPGSLRPTSLGFPARAG----QGRVQGAAPGRKLRGEPKTPPGRSG 147 + P EP PTS F A G ++ G L G P P G Sbjct: 185 PHPSVTPTGYHAPMEP----PTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA 240 Query: 148 PS--GGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRP 205 S GG G H + S +G PP + P P G P+ PP FP Sbjct: 241 ASSVGGPNGGKQHPPPTTP--ISVSSSGASG-APPTKPPTTPVGGGNLPSAPPPANFPHV 297 Query: 206 RTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPV--RPRLRVLTPPLALRCAL------PER 257 TP LPPP L A PP + +P L P A+ + PE+ Sbjct: 298 -TP--------NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348 Query: 258 G-SRTPSTRS---AVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPL 313 G + PS S A S + + + SS A S + SS A+P F ++ L Sbjct: 349 GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP---FPASQAL 405 Query: 314 PRPPSFVPSLPSPQAQGQAVRQPRLLRAALARGAPRGRTPSPRP 357 P S+ S P P + + + P+ + +L A + P P P Sbjct: 406 P---SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446 Score = 39.3 bits (90), Expect = 0.006 Identities = 43/159 (27%), Positives = 53/159 (33%), Gaps = 38/159 (23%) Query: 30 ALPPDRSPTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTR 89 A PP P + SPG A PG PG+P P R Sbjct: 631 ASPPGPPPYGKRAPSPGAYKTATPPGYK------------PGSP------------PSFR 666 Query: 90 QGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPS 149 G G PA PG+ +P S G G + A P G P PP + P+ Sbjct: 667 TGTPPGYRG--TSPPAGPGTFKPGS----PTVGPGPLPPAGPS----GLPSLPPPPAAPA 716 Query: 150 GGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPP 188 SG A + + + P PPAR P PP Sbjct: 717 ----SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751 Score = 33.1 bits (74), Expect = 0.45 Identities = 62/215 (28%), Positives = 76/215 (35%), Gaps = 34/215 (15%) Query: 33 PDRSPTPRSRVSPGVTSLAVGP-GNPTRCQR-SGVPYEGPGAPGGQQLRKSRARLPRTRQ 90 P+ P S S TS P +P+ Q G PY P P + S A L Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVP---TVTTSSATLSTVIA 619 Query: 91 GREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPG-RSGPS 149 + G + P PG P G A + PG K P +PP R+G Sbjct: 620 TVASSPAGYKTASP--PG---PPPYGKRAPSPGAYKTATPPGYK----PGSPPSFRTGTP 670 Query: 150 GGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPP 209 G R G A + G S GPGP P GP P+ PP P P P Sbjct: 671 PGYR-GTSPPAGPGTFKPG---SPTVGPGPLP-----PAGPSGLPSLPPPPAAPASGPPL 721 Query: 210 TC-----EPPSRKLPP--PLPLCRSRWVLAPPPPV 237 + EP P P+P RS +PPP V Sbjct: 722 SATQIKQEPAEEYETPESPVPPARSP---SPPPKV 753 Score = 30.4 bits (67), Expect = 2.9 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 20/99 (20%) Query: 169 AGFSVRNGPGPPARLPPAPPGPLLRPARPP--RPYFP---RPRTPP------------TC 211 AG+ + PGPP AP + A PP +P P R TPP T Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTF 685 Query: 212 EPPSRKL-PPPLPLCRSRWVLAPPPPVRPRLRVLTPPLA 249 +P S + P PLP + + PPP P PPL+ Sbjct: 686 KPGSPTVGPGPLPPAGPSGLPSLPPP--PAAPASGPPLS 722 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.136 0.427 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,544,289 Number of Sequences: 37866 Number of extensions: 1981867 Number of successful extensions: 28594 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 408 Number of HSP's successfully gapped in prelim test: 2043 Number of HSP's that attempted gapping in prelim test: 12721 Number of HSP's gapped (non-prelim): 10309 length of query: 398 length of database: 18,247,518 effective HSP length: 104 effective length of query: 294 effective length of database: 14,309,454 effective search space: 4206979476 effective search space used: 4206979476 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.