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Search of human proteins with 239744011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744011 PREDICTED: chromosome 10 open reading frame 112
[Homo sapiens]
(1817 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho... 3825 0.0
gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho... 3815 0.0
gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho... 3212 0.0
gi|119220585 apical early endosomal glycoprotein precursor [Homo... 193 1e-48
gi|223278413 MAM domain containing 2 [Homo sapiens] 141 5e-33
gi|24111244 MAM domain containing glycosylphosphatidylinositol a... 125 5e-28
gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens] 116 2e-25
gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens] 116 2e-25
gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 100 2e-20
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 100 2e-20
gi|223942069 enterokinase precursor [Homo sapiens] 99 3e-20
gi|65301164 very low density lipoprotein receptor isoform b [Hom... 99 5e-20
gi|65301167 very low density lipoprotein receptor isoform a [Hom... 99 5e-20
gi|93102379 low density lipoprotein-related protein 1B precursor... 96 3e-19
gi|4507157 sortilin-related receptor containing LDLR class A rep... 93 2e-18
gi|119709832 low density lipoprotein receptor-related protein 5 ... 92 4e-18
gi|66082554 low density lipoprotein receptor-related protein 8 i... 92 6e-18
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 91 8e-18
gi|61744471 low density lipoprotein receptor-related protein 8 i... 90 2e-17
gi|61744467 low density lipoprotein receptor-related protein 8 i... 90 2e-17
gi|65301119 low density lipoprotein receptor-related protein 8 i... 90 2e-17
gi|157384998 low density lipoprotein receptor-related protein 4 ... 90 2e-17
gi|148727288 low density lipoprotein receptor-related protein 6 ... 87 1e-16
gi|4504975 low density lipoprotein receptor precursor [Homo sapi... 85 7e-16
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 83 3e-15
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 83 3e-15
gi|134031945 SCO-spondin [Homo sapiens] 82 4e-15
gi|29244926 corin [Homo sapiens] 81 1e-14
gi|7706111 8D6 antigen [Homo sapiens] 79 3e-14
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 75 6e-13
>gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo
sapiens]
Length = 1817
Score = 3825 bits (9918), Expect = 0.0
Identities = 1817/1817 (100%), Positives = 1817/1817 (100%)
Query: 1 MSDVFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHL 60
MSDVFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHL
Sbjct: 1 MSDVFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHL 60
Query: 61 WVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES 120
WVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES
Sbjct: 61 WVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES 120
Query: 121 GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPV 180
GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPV
Sbjct: 121 GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPV 180
Query: 181 LTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA 240
LTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA
Sbjct: 181 LTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA 240
Query: 241 EAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANS 300
EAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANS
Sbjct: 241 EAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANS 300
Query: 301 CDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKL 360
CDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKL
Sbjct: 301 CDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKL 360
Query: 361 QSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQ 420
QSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQ
Sbjct: 361 QSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQ 420
Query: 421 LGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEK 480
LGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEK
Sbjct: 421 LGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEK 480
Query: 481 LRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMK 540
LRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMK
Sbjct: 481 LRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMK 540
Query: 541 DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY 600
DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY
Sbjct: 541 DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY 600
Query: 601 QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM 660
QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM
Sbjct: 601 QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM 660
Query: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS 720
DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS
Sbjct: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS 720
Query: 721 DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQ 780
DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQ
Sbjct: 721 DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQ 780
Query: 781 NTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV 840
NTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV
Sbjct: 781 NTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV 840
Query: 841 TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP 900
TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP
Sbjct: 841 TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP 900
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960
ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK
Sbjct: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960
Query: 961 DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK 1020
DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK
Sbjct: 961 DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK 1020
Query: 1021 NCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKF 1080
NCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKF
Sbjct: 1021 NCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKF 1080
Query: 1081 EGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQ 1140
EGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQ
Sbjct: 1081 EGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQ 1140
Query: 1141 SCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGN 1200
SCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGN
Sbjct: 1141 SCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGN 1200
Query: 1201 ENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDH 1260
ENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDH
Sbjct: 1201 ENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDH 1260
Query: 1261 TNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKRGRRR 1320
TNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKRGRRR
Sbjct: 1261 TNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKRGRRR 1320
Query: 1321 RRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQEKPNR 1380
RRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQEKPNR
Sbjct: 1321 RRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQEKPNR 1380
Query: 1381 RSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN 1440
RSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN
Sbjct: 1381 RSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN 1440
Query: 1441 FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEG 1500
FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEG
Sbjct: 1441 FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEG 1500
Query: 1501 SVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGW 1560
SVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGW
Sbjct: 1501 SVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGW 1560
Query: 1561 TYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSC 1620
TYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSC
Sbjct: 1561 TYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSC 1620
Query: 1621 IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVP 1680
IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVP
Sbjct: 1621 IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVP 1680
Query: 1681 DCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG 1740
DCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG
Sbjct: 1681 DCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG 1740
Query: 1741 IGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNP 1800
IGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNP
Sbjct: 1741 IGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNP 1800
Query: 1801 LYGTTSGSLETLSHHLK 1817
LYGTTSGSLETLSHHLK
Sbjct: 1801 LYGTTSGSLETLSHHLK 1817
>gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo
sapiens]
Length = 1817
Score = 3815 bits (9894), Expect = 0.0
Identities = 1811/1817 (99%), Positives = 1815/1817 (99%)
Query: 1 MSDVFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHL 60
MSDVFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHL
Sbjct: 1 MSDVFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHL 60
Query: 61 WVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES 120
WVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES
Sbjct: 61 WVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES 120
Query: 121 GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPV 180
GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPV
Sbjct: 121 GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPV 180
Query: 181 LTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA 240
LTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA
Sbjct: 181 LTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA 240
Query: 241 EAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANS 300
EAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANS
Sbjct: 241 EAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANS 300
Query: 301 CDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKL 360
CDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKL
Sbjct: 301 CDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKL 360
Query: 361 QSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQ 420
QSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQ
Sbjct: 361 QSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQ 420
Query: 421 LGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEK 480
LGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEK
Sbjct: 421 LGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEK 480
Query: 481 LRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMK 540
LRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTR+QGPTPTLNTGPMK
Sbjct: 481 LRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRNQGPTPTLNTGPMK 540
Query: 541 DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY 600
DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY
Sbjct: 541 DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY 600
Query: 601 QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM 660
QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM
Sbjct: 601 QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM 660
Query: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS 720
DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS
Sbjct: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS 720
Query: 721 DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQ 780
DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQ
Sbjct: 721 DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQ 780
Query: 781 NTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV 840
NTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV
Sbjct: 781 NTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV 840
Query: 841 TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP 900
TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP
Sbjct: 841 TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP 900
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960
ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK
Sbjct: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960
Query: 961 DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK 1020
DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK
Sbjct: 961 DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK 1020
Query: 1021 NCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKF 1080
NCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKF
Sbjct: 1021 NCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKF 1080
Query: 1081 EGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQ 1140
EGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQ
Sbjct: 1081 EGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQ 1140
Query: 1141 SCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGN 1200
SCNFVDNCGDNT EN+CGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGN
Sbjct: 1141 SCNFVDNCGDNTGENKCGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGN 1200
Query: 1201 ENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDH 1260
ENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDH
Sbjct: 1201 ENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDH 1260
Query: 1261 TNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKRGRRR 1320
NWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYF+SAKATGSIQILIKRGRRR
Sbjct: 1261 MNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFISAKATGSIQILIKRGRRR 1320
Query: 1321 RRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQEKPNR 1380
RRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQEKPNR
Sbjct: 1321 RRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQEKPNR 1380
Query: 1381 RSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN 1440
RSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN
Sbjct: 1381 RSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN 1440
Query: 1441 FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEG 1500
FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEG
Sbjct: 1441 FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEG 1500
Query: 1501 SVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGW 1560
SVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGW
Sbjct: 1501 SVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGW 1560
Query: 1561 TYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSC 1620
TYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSC
Sbjct: 1561 TYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSC 1620
Query: 1621 IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVP 1680
IYTLQCVPLSGKCDGHEDCIDGSDEMDCPL+PTPPLCSNMEFPCSTDECIPSLLLCDGVP
Sbjct: 1621 IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLNPTPPLCSNMEFPCSTDECIPSLLLCDGVP 1680
Query: 1681 DCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG 1740
DCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG
Sbjct: 1681 DCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG 1740
Query: 1741 IGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNP 1800
IGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNP
Sbjct: 1741 IGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNP 1800
Query: 1801 LYGTTSGSLETLSHHLK 1817
LYGTTSGSLETLSHHLK
Sbjct: 1801 LYGTTSGSLETLSHHLK 1817
>gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo
sapiens]
Length = 1542
Score = 3212 bits (8329), Expect = 0.0
Identities = 1517/1526 (99%), Positives = 1522/1526 (99%)
Query: 292 SKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKS 351
SKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKS
Sbjct: 17 SKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKS 76
Query: 352 SSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQG 411
SSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQG
Sbjct: 77 SSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQG 136
Query: 412 KQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWC 471
KQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWC
Sbjct: 137 KQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWC 196
Query: 472 RHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPT 531
RHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTR+QGPT
Sbjct: 197 RHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRNQGPT 256
Query: 532 PTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFG 591
PTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFG
Sbjct: 257 PTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFG 316
Query: 592 KRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGD 651
KRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGD
Sbjct: 317 KRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGD 376
Query: 652 IAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCD 711
IAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCD
Sbjct: 377 IAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCD 436
Query: 712 FKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEEN 771
FKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEEN
Sbjct: 437 FKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEEN 496
Query: 772 HRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSL 831
HRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSL
Sbjct: 497 HRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSL 556
Query: 832 QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF 891
QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF
Sbjct: 557 QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF 616
Query: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 951
QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF
Sbjct: 617 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 676
Query: 952 DLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARIS 1011
DLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFI SLFPQQPMRAARIS
Sbjct: 677 DLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPMRAARIS 736
Query: 1012 SPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLF 1071
SPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLF
Sbjct: 737 SPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLF 796
Query: 1072 GDEDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECH 1131
GDEDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECH
Sbjct: 797 GDEDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECH 856
Query: 1132 NGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLR 1191
NGKCYRLEQSCNFVDNCGDNT EN+CGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLR
Sbjct: 857 NGKCYRLEQSCNFVDNCGDNTGENKCGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLR 916
Query: 1192 PPKDHTLGNENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPN 1251
PPKDHTLGNENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPN
Sbjct: 917 PPKDHTLGNENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPN 976
Query: 1252 ENTFGSSDHTNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQ 1311
ENTFGSSDH NWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYF+SAKATGSIQ
Sbjct: 977 ENTFGSSDHMNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFISAKATGSIQ 1036
Query: 1312 ILIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLK 1371
ILIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLK
Sbjct: 1037 ILIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLK 1096
Query: 1372 GPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAH 1431
GPPQE+PNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCS RSDEAHCAH
Sbjct: 1097 GPPQEEPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSGRSDEAHCAH 1156
Query: 1432 YTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLY 1491
YTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLY
Sbjct: 1157 YTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLY 1216
Query: 1492 VNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWS 1551
VNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWS
Sbjct: 1217 VNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWS 1276
Query: 1552 VIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPS 1611
VIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPS
Sbjct: 1277 VIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPS 1336
Query: 1612 PCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
PCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPL+PTPPLCSNMEFPCSTDECIP
Sbjct: 1337 PCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLNPTPPLCSNMEFPCSTDECIP 1396
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS
Sbjct: 1397 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1456
Query: 1732 CSDTWTLLGIGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTE 1791
CSDTWTLLGIGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTE
Sbjct: 1457 CSDTWTLLGIGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTE 1516
Query: 1792 SSVYSFSNPLYGTTSGSLETLSHHLK 1817
SSVYSFSNPLYGTTSGSLETLSHHLK
Sbjct: 1517 SSVYSFSNPLYGTTSGSLETLSHHLK 1542
Score = 338 bits (867), Expect = 3e-92
Identities = 285/1010 (28%), Positives = 437/1010 (43%), Gaps = 168/1010 (16%)
Query: 116 CDFESGFCGWEPFLTEDSHWKLMKGLNNG-----EHHFPAADHTANINHGSFIYLEAQRS 170
CDFE+ C W ++ D H+ ++ + EH P DH+ N + G F+++ + S
Sbjct: 19 CDFEANSCDWFEAISGD-HFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSS 77
Query: 171 P--GVAKLGSPVLTKLLTASTPCQVQFW---YHLS-QHSNLSVFTRTSLDGN-----LQK 219
VAKL SP ++ C + FW Y LS + L + S D L
Sbjct: 78 SLWQVAKLQSPTFSQ---TGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYN 134
Query: 220 QGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLS-SNATVALDDISVSQECEIS 278
QGK QW A I L G + PF L L+ L + A+DDI + C +
Sbjct: 135 QGK-------QWLEATIQL----GRLSQPFHLSLDKVSLGIYDGVSAIDDIRF-ENCTL- 181
Query: 279 YKSLPRTS-----------TQSKFSK------------------------CDFEANSCDW 303
LP S T++ K C+FE C+W
Sbjct: 182 --PLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNW 239
Query: 304 FEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQ-VAKLQS 362
E + D FDW R+ + + P +D++L ++GH+++I +Q A L S
Sbjct: 240 -EQDAKDDFDWTRNQGPTPTL---NTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLS 295
Query: 363 PTFSQTG-PGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQL 421
P + T GC F+++ +G + + + + ++W++ NQG +W+ + +
Sbjct: 296 PILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNI 355
Query: 422 GRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTL-------------------PLPAES 462
QPF + ++ + G AIDD+ F +CTL LP +
Sbjct: 356 SS-RQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHN 414
Query: 463 CEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFE-TGICNWEQ----- 516
C + F CR CIEK++ CD DC D++DE +C E+ C+FE +C W Q
Sbjct: 415 CTD-NEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEV-CSFEKRSLCKWYQPIPVH 472
Query: 517 --DAKDDFDWTRSQGPT---PTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSP 571
+ F W G + N P D+T T G YLY +SS + F D+A +L+P
Sbjct: 473 LLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGK-FGDTADILTP 531
Query: 572 ILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNIS 631
I++ T K CT F+ HM G + L + I D+ LW G QG +W R + +
Sbjct: 532 IISLTGPK-CTLVFWTHMNGATVGSLQVL--IKKDNVTSKLWAQTGQQGAQWKRAEVFLG 588
Query: 632 SRQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCT 691
R QI+ A G + GD+A+DD+SF DC+ P+ P CT
Sbjct: 589 IRSHTQIVFRAKRGISYIGDVAVDDISFQDCS------------------PLLSPERKCT 630
Query: 692 DNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEV----CSFEKRSLCKWYQPIPVH 747
D+EF+C ++ HCI K + CDF DC D SDE + + C FE LC W Q
Sbjct: 631 DHEFMC-ANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE-FDLCSWKQ----- 683
Query: 748 LLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFG-DTADILTP 806
+ F W L G E P+ DHT + G Y++ +S + A I +P
Sbjct: 684 --EKDEDFDWNLKASSIPAAGTE---PAADHTLGNSSGHYIFINSLFPQQPMRAARISSP 738
Query: 807 IISLTGPKCTLVFWTHMNGATVGSLQVL-IKKDNVTSKLWAQTGQQGAQWKRAEVFLGIR 865
+IS C ++F HM G +G+L ++ + N T L T +QG W+R E+ L
Sbjct: 739 VISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGD 798
Query: 866 SHTQIVFRAKRGISYIGDVAVDDI-----------SFQDCSPLLSPERKCTDHEFMCANK 914
Q+ F + G GD+A+DDI S Q+ + P C C N
Sbjct: 799 EDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNG 858
Query: 915 HCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIP 974
C ++ C+FV++C DN+ E C +S C FE C W+ + ++FDW L S
Sbjct: 859 KCYRLEQSCNFVDNCGDNTGENK--CGSS---CTFEKGWCGWQNSQADNFDWVLGVGS-- 911
Query: 975 AAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKI 1024
P DHTLGN + + + +P + + + + ++ NC +
Sbjct: 912 HQSLRPPKDHTLGNENAILLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSV 961
Score = 297 bits (760), Expect = 7e-80
Identities = 229/839 (27%), Positives = 367/839 (43%), Gaps = 106/839 (12%)
Query: 9 SKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFI-ALDHLWVYACGQ 67
S + + W + QW++A + + + F + + L + A+D + C
Sbjct: 122 SHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTL 181
Query: 68 TQSRKLCSA-DEFPCTSGQ-CIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGW 125
+ C D F C + CI K +CD DC D +DE C+ L C+FE+G C W
Sbjct: 182 PLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDE--VNCAPELQCNFETGICNW 239
Query: 126 EPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEA---QRSPGVAKLGSPVLT 182
E +D W +G + P D+T G ++Y+E+ Q A L SP+L
Sbjct: 240 EQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILN 299
Query: 183 KLLTASTPCQVQFWYHL--SQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA 240
T + C +F+YH+ + L+++ R D Q +I ++W +++
Sbjct: 300 --ATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNI-- 355
Query: 241 EAGESTLPFQLILEATVLSS-NATVALDDISVSQECEISYKSL-------PRTSTQ---- 288
S PFQ+++EA+V +A+DD+S +C + +L P TS
Sbjct: 356 ---SSRQPFQILVEASVGDGFTGDIAIDDLSF-MDCTLYPGNLPADLPTPPETSVPVTLP 411
Query: 289 ------------------SKFSKCDF---------------------EANSCDWFEAI-- 307
K KCDF + + C W++ I
Sbjct: 412 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV 471
Query: 308 ----SGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKLQSP 363
+ F W + + E+ P DH+ N + G +++ + A + +P
Sbjct: 472 HLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTP 531
Query: 364 TFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGR 423
S TGP C L FW + G +VG+ LQ+ ++ + ++ +W QG QW A + LG
Sbjct: 532 IISLTGPKCTLVFWTHMNGATVGS--LQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGI 589
Query: 424 LSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRL 483
S + K + Y G A+DDI F++C+ PL + + DH + + CI K +L
Sbjct: 590 RSHTQIVFRAKRGIS-YIGDVAVDDISFQDCS-PLLSPERKCTDHEFMCANKHCIAKDKL 647
Query: 484 CDLVDDCGDRTDEVN--CAPEL-QCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMK 540
CD V+DC D +DE C +C+FE +C+W+Q+ +DFDW P T P
Sbjct: 648 CDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAA 707
Query: 541 DNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIY 600
D+TLG + GHY++I S PQ +A + SP+++ +K C F+YHM+G I L +
Sbjct: 708 DHTLGNSSGHYIFINSLFPQQPMRAARISSPVISKR-SKNCKIIFHYHMYGNGIGALTLM 766
Query: 601 QRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFM 660
Q + ++ ++L + QGN W R+ L++ + FQ+ E VG G GDIA+DD+
Sbjct: 767 Q-VSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLT 825
Query: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKS 720
+ L L + + V LP C C +G C Q C+F +C D +
Sbjct: 826 ENCL-------SLHDSVQEELAVPLPTGFCPLGYRECH-NGKCYRLEQSCNFVDNCGDNT 877
Query: 721 DEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHT 779
E C C+FEK C W ++ F W LG G ++ RP DHT
Sbjct: 878 GENKCGSS-CTFEK-GWCGWQN-------SQADNFDWVLGVG-----SHQSLRPPKDHT 922
Score = 167 bits (422), Expect = 1e-40
Identities = 155/538 (28%), Positives = 232/538 (43%), Gaps = 94/538 (17%)
Query: 74 CSADEFPCTS-GQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFES-GFCGW-EPF-- 128
C+ +EF C S G CI K CD + DC D+SDE A+C + C FE C W +P
Sbjct: 415 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE--ASCVMEV-CSFEKRSLCKWYQPIPV 471
Query: 129 -LTEDSH---WKLMKGL---NNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPVL 181
L +DS+ W L G+ + E+H P+ DHT N G ++Y A S G + +L
Sbjct: 472 HLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY--ADSSNGKFGDTADIL 529
Query: 182 TKLLTASTP-CQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIA 240
T +++ + P C + FW H++ + S+ D K +QW A++ L
Sbjct: 530 TPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGI 589
Query: 241 EAGESTLPFQLILEA-TVLSSNATVALDDISVSQECEISYKSLPRTSTQSKF-------- 291
+ Q++ A +S VA+DDIS Q+C S R T +F
Sbjct: 590 RSHT-----QIVFRAKRGISYIGDVAVDDISF-QDCS-PLLSPERKCTDHEFMCANKHCI 642
Query: 292 ---------------------------SKCDFEANSCDWFEAISGDHFDWIRSSQSELSA 324
+CDFE + C W + D FDW + S +A
Sbjct: 643 AKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDED-FDWNLKASSIPAA 701
Query: 325 DFEHQAPPRDHSLNASQGHFMFILKKSSSLW-----QVAKLQSPTFSQTGPGCILSFWFY 379
E P DH+L S GH++FI +SL+ + A++ SP S+ C + F ++
Sbjct: 702 GTE---PAADHTLGNSSGHYIFI----NSLFPQQPMRAARISSPVISKRSKNCKIIFHYH 754
Query: 380 NYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLD-KVSLG 438
YG +GA L + + ++ + V+ + QG W + L + F L + +V G
Sbjct: 755 MYGNGIGALTL-MQVSVTNQTKVLLNLTVEQGNFWRREELSLFG-DEDFQLKFEGRVGKG 812
Query: 439 IYDGVSAIDDIRFENC-----------TLPLPAESCEGLDHFWCRHTRACIEKLRLCDLV 487
++ D + ENC +PLP C L + C H C + C+ V
Sbjct: 813 QRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCP-LGYREC-HNGKCYRLEQSCNFV 870
Query: 488 DDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLG 545
D+CGD T E C C FE G C W+ D+FDW G +L P KD+TLG
Sbjct: 871 DNCGDNTGENKCGS--SCTFEKGWCGWQNSQADNFDWVLGVGSHQSLR--PPKDHTLG 924
Score = 108 bits (269), Expect = 6e-23
Identities = 103/388 (26%), Positives = 152/388 (39%), Gaps = 76/388 (19%)
Query: 4 VFLFKSKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTL-LSQRSFIALDHLWV 62
V + K W +QW +A+V + T +I+F +S +A+D +
Sbjct: 558 VLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHT-QIVFRAKRGISYIGDVAVDDISF 616
Query: 63 YACGQTQS-RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATC-SKHLTCDFES 120
C S + C+ EF C + CIAK+ +CD DC+D SDE C + CDFE
Sbjct: 617 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 676
Query: 121 GFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEA---QRSPGVAKLG 177
C W+ ED W L PAADHT + G +I++ + Q+ A++
Sbjct: 677 DLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPMRAARIS 736
Query: 178 SPVLTKLLTASTPCQVQFWYHLSQHS-------NLSVFTRTSLDGNLQ-KQGKIIRFSES 229
SPV++K S C++ F YH+ + +SV +T + NL +QG
Sbjct: 737 SPVISK---RSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNF------ 787
Query: 230 QWSHAKIDLIAEAGESTLPFQLILEATV-LSSNATVALDDI-----------SVSQE--- 274
W ++ L + FQL E V +ALDDI SV +E
Sbjct: 788 -WRREELSLFGDE-----DFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAV 841
Query: 275 ------CEISYKSL-------------------PRTSTQSKFSKCDFEANSCDWFEAISG 309
C + Y+ T S C FE C W +
Sbjct: 842 PLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTGENKCGSSCTFEKGWCGW-QNSQA 900
Query: 310 DHFDWIRSSQSELSADFEHQAPPRDHSL 337
D+FDW+ S S PP+DH+L
Sbjct: 901 DNFDWVLGVGSHQSL-----RPPKDHTL 923
Score = 62.4 bits (150), Expect = 4e-09
Identities = 55/212 (25%), Positives = 98/212 (46%), Gaps = 24/212 (11%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL----TCDFESGFCGWEP--FLTE 131
+F C +CIA +CD + DCS SDE A C+ + +C+FE+ W LT+
Sbjct: 1124 DFLCRDKKCIASHLLCDYKPDCSGRSDE--AHCAHYTSTTGSCNFETSSGNWTTACSLTQ 1181
Query: 132 DSHWKLMKGLNN---GEHHFPAADHT-ANINHGSFIYLEAQRSPGVAKLGSPVLTKLLTA 187
DS L + + + P +DHT + H ++ + VA++ +K A
Sbjct: 1182 DSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARI---TTSKSFPA 1238
Query: 188 ST-PCQVQFWYHLSQHSNLSVFTRTSLD--GNLQKQGKIIRFSESQWSHAKIDLIAEAGE 244
S C V+FW+++ ++ + +++ G +I + W++ + L
Sbjct: 1239 SLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPL-----S 1293
Query: 245 STLPFQLILEATV-LSSNATVALDDISVSQEC 275
S PF++ EA + + + +ALDDIS + EC
Sbjct: 1294 SNSPFKVAFEADLDGNEDIFIALDDISFTPEC 1325
Score = 38.5 bits (88), Expect = 0.060
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 8/99 (8%)
Query: 14 IFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRS-FIALDHL-----WVYACGQ 67
+ W+ + + W V + + FK+ FE L FIALD + V
Sbjct: 1273 LVWSVIGNKRTGWTYGSVPLSSN-SPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPV 1331
Query: 68 TQSRKLCSADEFPCT-SGQCIAKESVCDSRQDCSDESDE 105
C AD+F C + QC+ CD +DC D SDE
Sbjct: 1332 PVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE 1370
Score = 37.4 bits (85), Expect = 0.13
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 65 CGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C + LCS EFPC++ +CI +CD DC DE
Sbjct: 1373 CPLNPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDE 1413
>gi|119220585 apical early endosomal glycoprotein precursor [Homo
sapiens]
Length = 1137
Score = 193 bits (491), Expect = 1e-48
Identities = 148/543 (27%), Positives = 230/543 (42%), Gaps = 65/543 (11%)
Query: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
CDFE + C W + IS + W+R A E P DH+L G +M +
Sbjct: 66 CDFEQDPCGWRD-ISTSGYSWLRD---RAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGK 121
Query: 354 LWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQ 413
A L+SPT + C L W++ S AEL++ + + ++ +W+ G
Sbjct: 122 EASTAALRSPTLREAASSCKLRLWYH--AASGDVAELRVELTHGAETLTLWQSTGPWGPG 179
Query: 414 WLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRH 473
W E + GR+ F ++ + G A+DD+ F +C LP P +C H C++
Sbjct: 180 WQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPP-GHHHCQN 238
Query: 474 TRACIEKLRLCDLVDDCGDRTDE--VNCAPELQCNFETGICNWEQDAKDDFDWTRS-QGP 530
+ C+E +LCD D+CGD +DE + C + +FETG+ W + W+R+ +
Sbjct: 239 -KVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSE----GWSRNHRAG 293
Query: 531 TPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMF 590
P + P +D++ +A+G +L + +EP A L SP A+ T C+ FY ++
Sbjct: 294 GPERPSWPRRDHSRNSAQGSFL-VSVAEPGT---PAILSSPEFQASGTSNCSLVFYQYLS 349
Query: 591 GKRIYRLAIYQRIWSDSRGQ---LLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDG 647
G L ++ + + LL + G G W+R ++I S PFQIL+ G G
Sbjct: 350 GSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG 409
Query: 648 FTGDIAIDDLSFMD--------CTLYPGNLPADLPTPPETSVPVTLPP-----HNCTDNE 694
G + +DDL D TL P LP P P LPP +C
Sbjct: 410 --GVVGLDDLILSDHCRPVSEVSTLQP------LPPGPRAPAPQPLPPSSRLQDSCKQGH 461
Query: 695 FICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNT 754
C C+ Q CDF+ C DE +C FE W + V LQ
Sbjct: 462 LAC--GDLCVPPEQLCDFEEQCAGGEDEQAC--GTTDFESPEAGGW-EDASVGRLQ---- 512
Query: 755 FRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPK 814
W +S + + + H + W G+ G A +LTP++ +GP
Sbjct: 513 --W---RRVSAQESQGSSAAAAGHFLSLQRAW--------GQLGAEARVLTPLLGPSGPS 559
Query: 815 CTL 817
C L
Sbjct: 560 CEL 562
Score = 191 bits (484), Expect = 7e-48
Identities = 176/672 (26%), Positives = 268/672 (39%), Gaps = 85/672 (12%)
Query: 697 CRSDGHCIEKMQKCDFKYDCPDKSDEASCVME----------VCSFEKRSLCKWYQPIPV 746
CRS G + C+F DC D SDEA C C FE+ C W
Sbjct: 28 CRSPGQAV-----CNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDP-CGW------ 75
Query: 747 HLLQDSNT--FRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADIL 804
+D +T + W + G H DHT T GWY+ + GK TA +
Sbjct: 76 ---RDISTSGYSWLRDRAGAALEGPGPHS---DHTLGTDLGWYMAVGTHRGKEASTAALR 129
Query: 805 TPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLG- 863
+P + C L W H V L+V + T LW TG G W+ V G
Sbjct: 130 SPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGR 189
Query: 864 IRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLC 923
IR ++ F A R ++ G VA+DD+ F DC L +P+ C C NK C+ +LC
Sbjct: 190 IRGDFRVTFSATRNATHRGAVALDDLEFWDCG-LPTPQANCPPGHHHCQNKVCVEPQQLC 248
Query: 924 DFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAAD 983
D ++C D SDE C DFE L W + E + N +A P + P D
Sbjct: 249 DGEDNCGDLSDENPLTCGRHIA-TDFETGLGPW--NRSEGWSRNHRAGG-PERPSWPRRD 304
Query: 984 HTLGNSSGHYIFIKSLFPQQPMRAARISSPVI-SKRSKNCKIIFHYHMYGNGIGALTLMQ 1042
H+ ++ G ++ + +P A +SSP + + NC ++F+ ++ G+ G L L
Sbjct: 305 HSRNSAQGSFL----VSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFL 360
Query: 1043 VSV---TNQTKVLL-NLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIV 1098
++ + VLL E G W R+ + + FQ+ G+ G G G + LDD++
Sbjct: 361 QTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG--GVVGLDDLI 418
Query: 1099 LTENCLSLHDSVQEELAVPLPTG-----------------FCPLGYRECHNGKCYRLEQS 1141
L+++C + + PLP G C G+ C C EQ
Sbjct: 419 LSDHCRPVS---EVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC-GDLCVPPEQL 474
Query: 1142 CNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDW--VLGVGSHQSLRPPKDHTLG 1199
C+F + C DE CG++ GW+++ W V S S H L
Sbjct: 475 CDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLS 534
Query: 1200 NENA---ILLMRRHKYPI-----RSVNLHTVKHVLKAQTVGNCSVSK-----LEARLLDF 1246
+ A + R P+ S LH ++ +C+ + L D
Sbjct: 535 LQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHLSDT 594
Query: 1247 LSVPNENTFGSSDHT--NWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSA 1304
E+ DHT HF+ L+ T G AH S ++ +SFWY +
Sbjct: 595 HWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHG 654
Query: 1305 KATGSIQILIKR 1316
G++++ ++R
Sbjct: 655 PQIGTLRLAMRR 666
Score = 140 bits (354), Expect = 9e-33
Identities = 148/603 (24%), Positives = 235/603 (38%), Gaps = 124/603 (20%)
Query: 483 LCDLVDDCGDRTDEVNC-----APEL----QCNFETGICNWEQDAKDDFDWTRSQGPTPT 533
+C+ V DC D +DE C +P L C+FE C W + + W R +
Sbjct: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAAL 94
Query: 534 LNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKR 593
GP D+TLGT G Y+ + + + +AAL SP L C R +YH
Sbjct: 95 EGPGPHSDHTLGTDLGWYMAVGTHRGKE-ASTAALRSPTLREA-ASSCKLRLWYHAASGD 152
Query: 594 IYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISS---RQPFQILVEASVGDGFTG 650
+ L + + + LWQ G G W + L +++ R F++ A+ G
Sbjct: 153 VAELRV--ELTHGAETLTLWQSTGPWGPGW--QELAVTTGRIRGDFRVTFSATRNATHRG 208
Query: 651 DIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKC 710
+A+DDL F DC LPTP NC C++ C+E Q C
Sbjct: 209 AVALDDLEFWDC---------GLPTPQA----------NCPPGHHHCQNK-VCVEPQQLC 248
Query: 711 DFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV--HLLQDSNTFRWGLGNGISIHHG 768
D + +C D SDE P+ H+ D F GLG
Sbjct: 249 DGEDNCGDLSDE-------------------NPLTCGRHIATD---FETGLGPWNRSEGW 286
Query: 769 EENHR---------PSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG-PKCTLV 818
NHR P DH++N+ G +L S + G A + +P +G C+LV
Sbjct: 287 SRNHRAGGPERPSWPRRDHSRNSAQGSFLV---SVAEPGTPAILSSPEFQASGTSNCSLV 343
Query: 819 FWTHMNGATVGSLQVLIK-----KDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFR 873
F+ +++G+ G LQ+ ++ L + G+ G W R V + QI+
Sbjct: 344 FYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLA 403
Query: 874 AKRGISYIGDVAVDDISFQD-CSPL-----LSP-------------------ERKCTDHE 908
+ G G V +DD+ D C P+ L P + C
Sbjct: 404 GQTGPG--GVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGH 461
Query: 909 FMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF-DLCSWKQEKDEDFDWN 967
C + C+ ++LCDF CA DE + G DFE + W+ W
Sbjct: 462 LACGDL-CVPPEQLCDFEEQCAGGEDE------QACGTTDFESPEAGGWEDASVGRLQWR 514
Query: 968 LKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFH 1027
+ S+ + G+ AA +GH++ ++ + Q AR+ +P++ +C++
Sbjct: 515 -RVSAQESQGSSAAA-------AGHFLSLQRAWGQLGAE-ARVLTPLLGPSGPSCELHLA 565
Query: 1028 YHM 1030
Y++
Sbjct: 566 YYL 568
Score = 135 bits (339), Expect = 5e-31
Identities = 142/591 (24%), Positives = 238/591 (40%), Gaps = 105/591 (17%)
Query: 112 KHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSP 171
+ ++C+FE C W P D+HW+ + E P DHT H F+ L+ P
Sbjct: 573 REVSCNFERDTCSWYPGHLSDTHWRWV------ESRGPDHDHTTGQGH--FVLLDPT-DP 623
Query: 172 GVAKLGSPVLTKLLTASTPCQ-VQFWYHLS--QHSNLSVFTR-----TSLDGNLQKQGKI 223
+ +L++ + P + + FWYHL Q L + R T L QG
Sbjct: 624 LAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQG-- 681
Query: 224 IRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLP 283
++W A L + G S +QL+ E + T+ALDD++V
Sbjct: 682 -----NRWHEAWATLSHQPG-SHAQYQLLFEGLRDGYHGTMALDDVAV------------ 723
Query: 284 RTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGH 343
R + C FE + C + G W R + + A + PP DH+ +QGH
Sbjct: 724 RPGPCWAPNYCSFEDSDCGFSPGGQGL---WRRQANASGHAAW---GPPTDHTTETAQGH 777
Query: 344 FMFILKKSSSL--WQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDST 401
+M + +L Q A L S L+FW++ S G + L H
Sbjct: 778 YMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQ-- 835
Query: 402 VIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAE 461
+ + + G W ++ + + + + + + V+ G+ A+DD+ ++ P P
Sbjct: 836 -VLSLSAHGGLAWRLGSMDV-QAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS 893
Query: 462 SCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDA--- 518
C+FE+G+C W A
Sbjct: 894 -------------------------------------------CDFESGLCGWSHLAWPG 910
Query: 519 KDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDT 578
+ W G TP+ P D+TLGT GH+ + E+ +A L S L AT
Sbjct: 911 LGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPA 970
Query: 579 KGCTFRFYYHM-FGKRIYRLAIYQRIWSDSRGQL-LWQIFGNQGNRWIRKHLNISSRQPF 636
RF+YHM F + Y+ + + S ++GQL +W G++ ++W+ + ++S + F
Sbjct: 971 S--CLRFWYHMGFPEHFYKGELKVLLHS-AQGQLAVWGAGGHRRHQWLEAQVEVASAKEF 1027
Query: 637 QILVEASV-GDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLP 686
QI+ EA++ G G IA+DD+ + L + P+P T+ P ++P
Sbjct: 1028 QIVFEATLGGQPALGPIALDDVEY----LAGQHCQQPAPSPGNTAAPGSVP 1074
Score = 103 bits (256), Expect = 2e-21
Identities = 154/667 (23%), Positives = 235/667 (35%), Gaps = 159/667 (23%)
Query: 250 QLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEA-IS 308
QL EA VL T L S E ++Y +Q + C+FE ++C W+ +S
Sbjct: 541 QLGAEARVL----TPLLGPSGPSCELHLAYY----LQSQPREVSCNFERDTCSWYPGHLS 592
Query: 309 GDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLW-QVAKLQSPTFSQ 367
H+ W+ E + P DH+ QGHF+ + W A L S
Sbjct: 593 DTHWRWV-----------ESRGPDHDHT--TGQGHFVLLDPTDPLAWGHSAHLLSRPQVP 639
Query: 368 TGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQP 427
P LSFW++ +G +G L+L M + T +W QG +W EA L QP
Sbjct: 640 AAPTECLSFWYHLHGPQIGT--LRLAMRREGEETHLWSRSGTQGNRWHEAWATLSH--QP 695
Query: 428 -FHLSLDKVSLGI---YDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRL 483
H + G+ Y G A+DD+ P P
Sbjct: 696 GSHAQYQLLFEGLRDGYHGTMALDDV----AVRPGP------------------------ 727
Query: 484 CDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNT 543
C C+FE C + + W R + GP D+T
Sbjct: 728 ---------------CWAPNYCSFEDSDCGFSPGGQG--LWRRQANASGHAAWGPPTDHT 770
Query: 544 LGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRI 603
TA+GHY+ +++S + A L+ + + F+YH + L +Y +
Sbjct: 771 TETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVY--L 828
Query: 604 WSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCT 663
R Q+L + + G W +++ + + ++++ EA +A+DDL
Sbjct: 829 EERGRHQVL-SLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDL------ 881
Query: 664 LYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA 723
L D P P S CDF
Sbjct: 882 -----LLQDGPCPQPGS-----------------------------CDF----------- 896
Query: 724 SCVMEVCSFEKRSLCKWYQPIPVHLLQDS-NTFRWGLGNGISIHHGEENHRPSVDHTQNT 782
+ LC W HL + W G G + +P VDHT T
Sbjct: 897 ----------ESGLCGW-----SHLAWPGLGGYSWDWGGGAT---PSRYPQPPVDHTLGT 938
Query: 783 TDGWYLYADSS-NGKFGDTADILTPIISLTGPKCTLVFWTHMNGAT---VGSLQVLIKKD 838
G + + ++ G G A + + + T C L FW HM G L+VL+
Sbjct: 939 EAGHFAFFETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSA 997
Query: 839 NVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAK-RGISYIGDVAVDDISF---QDC 894
+W G + QW A+V + QIVF A G +G +A+DD+ + Q C
Sbjct: 998 QGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHC 1057
Query: 895 -SPLLSP 900
P SP
Sbjct: 1058 QQPAPSP 1064
Score = 95.9 bits (237), Expect = 3e-19
Identities = 105/429 (24%), Positives = 166/429 (38%), Gaps = 76/429 (17%)
Query: 40 FKIIFEGTL-LSQRSFIALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQD 98
F++ F T + R +ALD L + CG + C C + C+ + +CD +
Sbjct: 194 FRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDN 253
Query: 99 CSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEH-HFPAADHTANI 157
C D SDE+P TC +H+ DFE+G W W E +P DH+ N
Sbjct: 254 CGDLSDENPLTCGRHIATDFETGLGPW----NRSEGWSRNHRAGGPERPSWPRRDHSRNS 309
Query: 158 NHGSFIYLEAQRSPGV-AKLGSPVLTKLLTASTPCQVQFWYHL--SQHSNLSVFTRTSLD 214
GSF+ A+ PG A L SP + ++ C + F+ +L S+ L +F +T L
Sbjct: 310 AQGSFLVSVAE--PGTPAILSSPEFQ--ASGTSNCSLVFYQYLSGSEAGCLQLFLQT-LG 364
Query: 215 GNLQKQGKIIRFSESQ----WSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDIS 270
+ ++R + W ++D+ +S PFQ++L A V LDD+
Sbjct: 365 PGAPRAPVLLRRRRGELGTAWVRDRVDI-----QSAYPFQILL-AGQTGPGGVVGLDDLI 418
Query: 271 VSQEC----EISY-------------KSLPRTSTQSKFSK----------------CDFE 297
+S C E+S + LP +S K CDFE
Sbjct: 419 LSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFE 478
Query: 298 --------ANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILK 349
+C + S + W +S L A S A+ GHF+ + +
Sbjct: 479 EQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWR-RVSAQESQGSSAAAAGHFLSLQR 537
Query: 350 KSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMEN-------SHDSTV 402
L A++ +P +GP C L +Y L E+ + E H S
Sbjct: 538 AWGQLGAEARVLTPLLGPSGPSCELHLAYY---LQSQPREVSCNFERDTCSWYPGHLSDT 594
Query: 403 IWRVLYNQG 411
WR + ++G
Sbjct: 595 HWRWVESRG 603
Score = 91.3 bits (225), Expect = 8e-18
Identities = 109/483 (22%), Positives = 178/483 (36%), Gaps = 131/483 (27%)
Query: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY 789
C+FE R C WY P HL +RW E+ P DHT T G ++
Sbjct: 577 CNFE-RDTCSWY---PGHL--SDTHWRW-----------VESRGPDHDHT--TGQGHFVL 617
Query: 790 ADSSNG-KFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQT 848
D ++ +G +A +L+ P L FW H++G +G+L++ ++++ + LW+++
Sbjct: 618 LDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRS 677
Query: 849 GQQGAQWKRAEVFL----GIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKC 904
G QG +W A L G + Q++F R Y G +A+DD++ + P +P
Sbjct: 678 GTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRD-GYHGTMALDDVAVRP-GPCWAP---- 731
Query: 905 TDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDF 964
+C +D C F S G
Sbjct: 732 ---------NYCSFEDSDCGF-----------------SPGGQGL--------------- 750
Query: 965 DWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPM-RAARISSPVISKRSKNCK 1023
W +A++ A P DHT + GHY+ + + P + A ++S ++
Sbjct: 751 -WRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC 809
Query: 1024 IIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGR 1083
+ F YH G+ TL +L+L+ G WR + + + +++ FE
Sbjct: 810 LTFWYH--GSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAV 867
Query: 1084 VGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCN 1143
+ALDD++L + G CP
Sbjct: 868 AAGVAHSYVALDDLLLQD-------------------GPCPQ------------------ 890
Query: 1144 FVDNCGDNTDENECGSSCTFEKGWCGWQNSQ-----ADNFDWVLGVGSHQSLRPPKDHTL 1198
SC FE G CGW + ++DW G + +PP DHTL
Sbjct: 891 --------------PGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTL 936
Query: 1199 GNE 1201
G E
Sbjct: 937 GTE 939
Score = 80.9 bits (198), Expect = 1e-14
Identities = 136/569 (23%), Positives = 210/569 (36%), Gaps = 102/569 (17%)
Query: 90 ESVCDSRQDCSDESDEDPATCSKH---------LTCDFESGFCGWEPFLTEDSHWKLMKG 140
++VC+ DC D SDE A C H CDFE CGW T W +
Sbjct: 33 QAVCNFVCDCRDCSDE--AQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRA 90
Query: 141 LNNGEHHFPAADHTANINHGSFIYLEAQR--SPGVAKLGSPVLTKLLTASTPCQVQFWYH 198
E P +DHT + G ++ + R A L SP L + A++ C+++ WYH
Sbjct: 91 GAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLRE---AASSCKLRLWYH 147
Query: 199 LSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVL 258
+ + R L + + S W +L G F++ AT
Sbjct: 148 AASGDVAEL--RVELTHGAET--LTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRN 203
Query: 259 SSN-ATVALDDI--------SVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFE---A 306
+++ VALDD+ + C + CD E N D +
Sbjct: 204 ATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPL 263
Query: 307 ISGDHF---------DWIRS---SQSELSADFEHQA-PPRDHSLNASQGHFMFILKKSSS 353
G H W RS S++ + E + P RDHS N++QG F+ + + +
Sbjct: 264 TCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGT 323
Query: 354 LWQVAKLQSPTFSQTG-PGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQ-- 410
A L SP F +G C L F+ Y G G LQL ++ VL +
Sbjct: 324 ---PAILSSPEFQASGTSNCSLVFYQYLSGSEAGC--LQLFLQTLGPGAPRAPVLLRRRR 378
Query: 411 ---GKQWLEATIQLGRLSQPFHLSL-DKVSLGIYDGVSAIDD-IRFENC-------TL-P 457
G W+ + + + + PF + L + G GV +DD I ++C TL P
Sbjct: 379 GELGTAWVRDRVDI-QSAYPFQILLAGQTGPG---GVVGLDDLILSDHCRPVSEVSTLQP 434
Query: 458 LP-----------------AESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA 500
LP +SC+ H C C+ +LCD + C DE C
Sbjct: 435 LPPGPRAPAPQPLPPSSRLQDSCK-QGHLACGD--LCVPPEQLCDFEEQCAGGEDEQACG 491
Query: 501 PELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQ 560
+ E G WE + W R + + A GH+L ++ + Q
Sbjct: 492 TTDFESPEAG--GWEDASVGRLQWRRV--------SAQESQGSSAAAAGHFLSLQRAWGQ 541
Query: 561 AFQDSAALLSPILNATDTKGCTFRFYYHM 589
+ A +L+P+L + C Y++
Sbjct: 542 LGAE-ARVLTPLLGPSG-PSCELHLAYYL 568
Score = 75.9 bits (185), Expect = 3e-13
Identities = 86/384 (22%), Positives = 150/384 (39%), Gaps = 75/384 (19%)
Query: 107 PATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLE 166
P C C FE CG+ P W+ + P DHT G ++ ++
Sbjct: 725 PGPCWAPNYCSFEDSDCGFSP--GGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVD 782
Query: 167 AQRSPGVAKLGSPVLTKLLTA------STPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQ 220
SP G T LT+ + P + FWYH G+L+
Sbjct: 783 T--SPDALPRGQ---TASLTSKEHRPLAQPACLTFWYH----------------GSLRSP 821
Query: 221 GKIIRFSESQWSHAKIDLIAEAG----------ESTLPFQLILEATVLS-SNATVALDDI 269
G + + E + H + L A G ++ ++++ EA +++ VALDD+
Sbjct: 822 GTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDL 881
Query: 270 SVSQECEISYKSLPRTSTQSKFSKCDFEANSCDW----FEAISGDHFDWIRSSQSELSAD 325
L + + CDFE+ C W + + G +DW +
Sbjct: 882 ------------LLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPS---- 925
Query: 326 FEHQAPPRDHSLNASQGHFMFILKKSSSLW---QVAKLQSPTFSQTGPGCILSFWFY-NY 381
+ PP DH+L GHF F ++ L + A L+S T C L FW++ +
Sbjct: 926 -RYPQPPVDHTLGTEAGHFAFF--ETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGF 981
Query: 382 GLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYD 441
EL++ + ++ +W ++ QWLEA +++ ++ F + + +LG
Sbjct: 982 PEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVAS-AKEFQIVFE-ATLGGQP 1039
Query: 442 --GVSAIDDIRF---ENCTLPLPA 460
G A+DD+ + ++C P P+
Sbjct: 1040 ALGPIALDDVEYLAGQHCQQPAPS 1063
Score = 73.9 bits (180), Expect = 1e-12
Identities = 78/336 (23%), Positives = 126/336 (37%), Gaps = 63/336 (18%)
Query: 774 PSVDHTQNTTDGWYLYADSSNGKF--GDTADILTPIISLTGPKCTLVFWTHMNGATVGSL 831
P DHT T G Y+ D+S G TA + + L FW H + + G+L
Sbjct: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
Query: 832 QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF 891
+V +++ ++ + + G W+ + + ++VF A VA+DD+
Sbjct: 825 RVYLEERG-RHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLL 883
Query: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 951
QD P P G CDFE
Sbjct: 884 QD-GPCPQP--------------------------------------------GSCDFES 898
Query: 952 DLCSWKQEKDED---FDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAA 1008
LC W + W+ + P+ +P DHTLG +GH+ F ++ RAA
Sbjct: 899 GLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAA 958
Query: 1009 RISSPVISKRSKNCKIIFHYHMYGNGI------GALTLMQVSVTNQTKVLLNLTVEQGNF 1062
+ S + +C + F YHM G G L ++ S Q V + +
Sbjct: 959 WLRSEPLPATPASC-LRFWYHM---GFPEHFYKGELKVLLHSAQGQLAV-WGAGGHRRHQ 1013
Query: 1063 WRREELSLFGDEDFQLKFEGRV-GKGQRGDIALDDI 1097
W ++ + ++FQ+ FE + G+ G IALDD+
Sbjct: 1014 WLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDV 1049
Score = 65.5 bits (158), Expect = 5e-10
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 10/177 (5%)
Query: 1437 GSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGS-GQHFLYVNSS 1495
GSC+FE+ W+ DW G P++ P DHT G+ HF + +
Sbjct: 892 GSCDFESGLCGWSHLAWPGLGGYS-WDWG-GGATPSRYPQPPVDHTLGTEAGHFAFFETG 949
Query: 1496 GSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSM--GILKVYTIEESGLNILVWSVI 1553
G A S+ PA+ C +RFW++M P G LKV G + VW
Sbjct: 950 VLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSAQG-QLAVWGAG 1007
Query: 1554 GNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIF-IALDDISFT--PECVTGGPVP 1607
G++R W V ++S F++ FEA L G + IALDD+ + C P P
Sbjct: 1008 GHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSP 1064
Score = 64.3 bits (155), Expect = 1e-09
Identities = 62/240 (25%), Positives = 99/240 (41%), Gaps = 21/240 (8%)
Query: 1413 LCDYKPDCSDRSDEAHCAHY--TSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIG 1467
+C++ DC D SDEA C ++ + T G +C+FE W ++ L G
Sbjct: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWR---DISTSGYSWLRDRAG 91
Query: 1468 SRIPAKALIPDSDHTPGSG-QHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYM 1526
+ + P SDHT G+ ++ V + KE S A + S + + C +R W++
Sbjct: 92 AALEGPG--PHSDHTLGTDLGWYMAVGTHRGKEASTAAL-RSPTLREAASSCKLRLWYHA 148
Query: 1527 IDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSS-NSPFKVAFEADLDGNE 1585
+ L+V + + +W G GW +V F+V F A +
Sbjct: 149 AS-GDVAELRV-ELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATH 206
Query: 1586 DIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE 1645
+ALDD+ F +C +P + C C CV CDG ++C D SDE
Sbjct: 207 RGAVALDDLEFW-DC----GLPTPQANCPPGHHHC-QNKVCVEPQQLCDGEDNCGDLSDE 260
Score = 62.8 bits (151), Expect = 3e-09
Identities = 101/435 (23%), Positives = 153/435 (35%), Gaps = 89/435 (20%)
Query: 1258 SDHT-----NWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQI 1312
SDHT W+ T G A RS RE++++C + WY ++ +++
Sbjct: 101 SDHTLGTDLGWYMAV--GTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRV 158
Query: 1313 LIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLK- 1371
+ G A L S G Q+L G F R A+
Sbjct: 159 ELTHG-----AETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALD 213
Query: 1372 -------GPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRS 1424
G P + N CP C++K C+ LCD + +C D S
Sbjct: 214 DLEFWDCGLPTPQAN--------------CPP-GHHHCQNKVCVEPQQLCDGEDNCGDLS 258
Query: 1425 DE--AHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRI--PAKALIPDSD 1480
DE C + +T +FET G W + W+ R P + P D
Sbjct: 259 DENPLTCGRHIAT----DFETGLGPWNRS----------EGWSRNHRAGGPERPSWPRRD 304
Query: 1481 HTPGSGQHFLYVNSSGSKEGSVARITTSKSFPAS-LGMCTVRFWFYMIDPRSMGILKVYT 1539
H+ S Q V+ + E I +S F AS C++ F+ Y+ + G L+++
Sbjct: 305 HSRNSAQGSFLVSVA---EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEA-GCLQLF- 359
Query: 1540 IEESG-----LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDI 1594
++ G +L+ G T W V + S PF++ A G + + LDD+
Sbjct: 360 LQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILL-AGQTGPGGV-VGLDDL 417
Query: 1595 SFTPEC-----------VTGGPVPVQPSP----------CEADQFSCIYTLQCVPLSGKC 1633
+ C + GP P P C+ +C CVP C
Sbjct: 418 ILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC--GDLCVPPEQLC 475
Query: 1634 DGHEDCIDGSDEMDC 1648
D E C G DE C
Sbjct: 476 DFEEQCAGGEDEQAC 490
Score = 57.8 bits (138), Expect = 1e-07
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 13/147 (8%)
Query: 1477 PDSDHTPGSGQ-HFLYVNSSGSK--EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMG 1533
P +DHT + Q H++ V++S G A +T+ + P + C + FW++ RS G
Sbjct: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC-LTFWYHG-SLRSPG 822
Query: 1534 ILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDD 1593
L+VY E +L S G W GS+ + + ++V FEA G ++ALDD
Sbjct: 823 TLRVYLEERGRHQVLSLSAHGG--LAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDD 880
Query: 1594 ISFTPECVTGGPVPVQPSPCEADQFSC 1620
+ + GP P QP C+ + C
Sbjct: 881 L-----LLQDGPCP-QPGSCDFESGLC 901
Score = 53.5 bits (127), Expect = 2e-06
Identities = 55/213 (25%), Positives = 85/213 (39%), Gaps = 34/213 (15%)
Query: 1421 SDRSDEAHCAHYTSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIP 1477
S S E H A+Y + SCNFE + CS D W ++ P
Sbjct: 556 SGPSCELHLAYYLQSQPREVSCNFERDT------CSWYPGHLSDTHWRW-----VESRGP 604
Query: 1478 DSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKV 1537
D DHT G G L + G A + + PA+ C + FW+++ P+ +G L++
Sbjct: 605 DHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTEC-LSFWYHLHGPQ-IGTLRL 662
Query: 1538 YTIEESGLNILVWSVIGNKRTGWTYGSVPLS----SNSPFKVAFEADLDGNEDIFIALDD 1593
+ G +WS G + W LS S++ +++ FE DG +ALDD
Sbjct: 663 -AMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGT-MALDD 720
Query: 1594 ISFTPECVTGGPVPVQPSPCEADQFSCIYTLQC 1626
++ V+P PC A + C
Sbjct: 721 VA------------VRPGPCWAPNYCSFEDSDC 741
Score = 31.2 bits (69), Expect = 9.6
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
Query: 1258 SDHTN----WHFMYLEATAVGL-RGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQI 1312
+DHT H+M ++ + L RG A S R + ++FWY S ++ G++++
Sbjct: 767 TDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRV 826
Query: 1313 -LIKRGRRR 1320
L +RGR +
Sbjct: 827 YLEERGRHQ 835
>gi|223278413 MAM domain containing 2 [Homo sapiens]
Length = 686
Score = 141 bits (356), Expect = 5e-33
Identities = 174/678 (25%), Positives = 269/678 (39%), Gaps = 136/678 (20%)
Query: 2 SDVFLFKSKEEEIF----WTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIAL 57
S + L+ E+E F W+ + S W+ A + + K FKI+ EG L
Sbjct: 98 SQLNLYMRFEDESFDRLLWSAKEPSDS-WLIASLDLQNSSKKFKILIEGVL--------- 147
Query: 58 DHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCD 117
G T S L E T+G CI CD
Sbjct: 148 ------GQGNTASIALF---EIKMTTGYCIE---------------------------CD 171
Query: 118 FESG-FCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEA---QRSPGV 173
FE CG+ + +W + G H DHT G ++Y+++ + V
Sbjct: 172 FEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELGHYMYVDSVYVKHFQEV 231
Query: 174 AKLGSPVLTKLLTASTPCQVQFWYHLSQHSN--LSVFTRTSLDGNLQKQGKIIRFSESQW 231
A+L SP L TA + F+Y + Q ++ S++TR + G ++ K R + W
Sbjct: 232 AQLISP----LTTAPMAGCLSFYYQIQQGNDNVFSLYTR-DVAGLYEEIWKADRPGNAAW 286
Query: 232 SHAKIDLIAEAGESTLPFQLILEATVLS-SNATVALDDISVSQ-ECEISYKSLPRTSTQS 289
+ A+++ A P ++I E VALDDIS S C+ T+
Sbjct: 287 NLAEVEFSAP-----YPMEVIFEVAFNGPKGGYVALDDISFSPVHCQ--------NQTEL 333
Query: 290 KFS----KCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFM 345
FS C+FE + C++++ G + ++ + A DH+ G+++
Sbjct: 334 LFSAVEASCNFEQDLCNFYQDKEGPGWTRVKVKPNMYRAG--------DHTTGL--GYYL 383
Query: 346 FILKK-SSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHM--ENSHDSTV 402
K +S + +L P+ C L F + YG + L +++ EN
Sbjct: 384 LANTKFTSQPGYIGRLYGPSLPGNLQYC-LRFHYAIYGFLKMSDTLAVYIFEENHVVQEK 442
Query: 403 IWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYD-GVSAIDDIRFENCTLPLPAE 461
IW VL + W++A I + P + + +D G+ A+DDI +
Sbjct: 443 IWSVLESPRGVWMQAEITFKK-PMPTKVVFMSLCKSFWDCGLVALDDITIQ-------LG 494
Query: 462 SCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDD 521
SC EKL P +C FE C + Q+ ++
Sbjct: 495 SCSSS------------EKLP-----------------PPPGECTFEQDECTFTQEKRNR 525
Query: 522 FDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGC 581
W R +G TPT TGP D+T G G+Y+YIE+S + A LLS L K C
Sbjct: 526 SSWHRRRGETPTSYTGPKGDHTTGV--GYYMYIEASH-MVYGQKARLLSRPLRGVSGKHC 582
Query: 582 TFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVE 641
F+YHM+G L++Y + DS LLW+ G Q W+R + S + QI+ E
Sbjct: 583 -LTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEYSCERQHQIIFE 641
Query: 642 ASVGDGFTGDIAIDDLSF 659
A G DIAIDD+ F
Sbjct: 642 AIRGVSIRSDIAIDDVKF 659
Score = 124 bits (311), Expect = 8e-28
Identities = 173/785 (22%), Positives = 294/785 (37%), Gaps = 156/785 (19%)
Query: 115 TCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVA 174
+C FE CG++ L + + N E H+ D + + L SP +
Sbjct: 25 SCAFEESTCGFDSVLAS------LPWILNEEGHYIYVDTSFGKQGEKAVLL----SPDLQ 74
Query: 175 KLGSPVLTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHA 234
L + +T + LS S L+++ R D + + + W A
Sbjct: 75 AEEWSCLRLVYQITTSSE-----SLSDPSQLNLYMRFE-DESFDRLLWSAKEPSDSWLIA 128
Query: 235 KIDLIAEAGESTLPFQLILEATVLSSN-ATVALDDISVSQECEISYKSLPRTSTQSKFSK 293
+DL S+ F++++E + N A++AL +I + T +
Sbjct: 129 SLDL----QNSSKKFKILIEGVLGQGNTASIALFEIKM---------------TTGYCIE 169
Query: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
CDFE N F + +W S + H P+DH+ + GH+M++
Sbjct: 170 CDFEENHLCGFVNRWNPNVNWFVGGGSIRNV---HSILPQDHTFKSELGHYMYVDSVYVK 226
Query: 354 LWQ-VAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGK 412
+Q VA+L SP + GC+ ++ G + + ++ IW+
Sbjct: 227 HFQEVAQLISPLTTAPMAGCLSFYYQIQQGNDNVFSLYTRDVAGLYEE--IWKADRPGNA 284
Query: 413 QWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCR 472
W A ++ P + + G G A+DDI F
Sbjct: 285 AWNLAEVEFSA-PYPMEVIFEVAFNGPKGGYVALDDISFSPV------------------ 325
Query: 473 HTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTP 532
C ++T+ + A E CNFE +CN+ QD K+ WTR +
Sbjct: 326 ----------------HCQNQTELLFSAVEASCNFEQDLCNFYQD-KEGPGWTRVKVKPN 368
Query: 533 TLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFG- 591
G D+T G G+YL + L P L + + C RF+Y ++G
Sbjct: 369 MYRAG---DHTTGL--GYYLLANTKFTSQPGYIGRLYGPSLPG-NLQYC-LRFHYAIYGF 421
Query: 592 -KRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTG 650
K LA+Y + + +W + + W++ + P +++ +
Sbjct: 422 LKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEITFKKPMPTKVVFMSLC------ 475
Query: 651 DIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKC 710
SF DC L + +T+ +C+ +E + G C + +C
Sbjct: 476 ------KSFWDCGLVALD-------------DITIQLGSCSSSEKLPPPPGECTFEQDEC 516
Query: 711 DFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEE 770
F + EKR+ W++ G + + G
Sbjct: 517 TF------------------TQEKRNRSSWHR---------------RRGETPTSYTG-- 541
Query: 771 NHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILT-PIISLTGPKCTLVFWTHMNGATVG 829
P DHT T G+Y+Y ++S+ +G A +L+ P+ ++G C L F+ HM G G
Sbjct: 542 ---PKGDHT--TGVGYYMYIEASHMVYGQKARLLSRPLRGVSGKHC-LTFFYHMYGGGTG 595
Query: 830 SLQVLIKK--DNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVD 887
L V +KK D+ S LW + G+Q W RA + QI+F A RG+S D+A+D
Sbjct: 596 LLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEYSCERQHQIIFEAIRGVSIRSDIAID 655
Query: 888 DISFQ 892
D+ FQ
Sbjct: 656 DVKFQ 660
Score = 120 bits (301), Expect = 1e-26
Identities = 143/629 (22%), Positives = 238/629 (37%), Gaps = 142/629 (22%)
Query: 503 LQCNFETG-ICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQA 561
++C+FE +C + + +W G +++ +D+T + GHY+Y++S +
Sbjct: 168 IECDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELGHYMYVDSVYVKH 227
Query: 562 FQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRL------AIYQRIW-SDSRGQLLWQ 614
FQ+ A L+SP+ A +F + ++ L +Y+ IW +D G W
Sbjct: 228 FQEVAQLISPLTTAPMAGCLSFYYQIQQGNDNVFSLYTRDVAGLYEEIWKADRPGNAAWN 287
Query: 615 IFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLP 674
+ + S+ P +++ E + G +A+DD+SF
Sbjct: 288 L----------AEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFS-------------- 323
Query: 675 TPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEK 734
P H E + S V C+FE+
Sbjct: 324 -----------PVHCQNQTELLF--------------------------SAVEASCNFEQ 346
Query: 735 RSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSN 794
LC +YQ G G + + N + DHT T G+YL A N
Sbjct: 347 -DLCNFYQDKE--------------GPGWTRVKVKPNMYRAGDHT--TGLGYYLLA---N 386
Query: 795 GKFGDTADILTPIISLTGPKCTLVFWTHMNGATVG------SLQVLIKKDN--VTSKLWA 846
KF + + + P L + + A G +L V I ++N V K+W+
Sbjct: 387 TKFTSQPGYIGRLYGPSLPG-NLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWS 445
Query: 847 QTGQQGAQWKRAEVFLGIRSHTQIVFRAK-RGISYIGDVAVDDISFQDCSPLLSPERKCT 905
W +AE+ T++VF + + G VA+DDI+ Q S
Sbjct: 446 VLESPRGVWMQAEITFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGS---------- 495
Query: 906 DHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFD 965
C + +KL G C FE D C++ QEK
Sbjct: 496 ----------CSSSEKL------------------PPPPGECTFEQDECTFTQEKRNRSS 527
Query: 966 WNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKII 1025
W+ + P + T P DHT G G+Y++I++ +A +S P+ K+C +
Sbjct: 528 WHRRRGETPTSYTGPKGDHTTG--VGYYMYIEASHMVYGQKARLLSRPLRGVSGKHC-LT 584
Query: 1026 FHYHMYGNGIGALTL-MQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGRV 1084
F YHMYG G G L++ ++ ++ +L EQ W R + + Q+ FE
Sbjct: 585 FFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEYSCERQHQIIFEAIR 644
Query: 1085 GKGQRGDIALDDIVLTEN-CLSLHDSVQE 1112
G R DIA+DD+ C + D+ Q+
Sbjct: 645 GVSIRSDIAIDDVKFQAGPCGEMEDTTQQ 673
Score = 83.6 bits (205), Expect = 2e-15
Identities = 132/595 (22%), Positives = 222/595 (37%), Gaps = 139/595 (23%)
Query: 548 KGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIY---RLAIYQRIW 604
+GHY+Y+++S + + A LLSP L A + + + + +L +Y R
Sbjct: 49 EGHYIYVDTSFGKQ-GEKAVLLSPDLQAEEWSCLRLVYQITTSSESLSDPSQLNLYMRFE 107
Query: 605 SDSRGQLLWQIFGNQGNRWIRKHLNI-SSRQPFQILVEASVGDGFTGDIAIDDLSFMDCT 663
+S +LLW + W+ L++ +S + F+IL+E +G G T IA+ ++
Sbjct: 108 DESFDRLLWSA-KEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKM---- 162
Query: 664 LYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA 723
+ G+CIE CDF+ +
Sbjct: 163 -----------------------------------TTGYCIE----CDFEEN-------- 175
Query: 724 SCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTT 783
+C F R W + W +G G SI + + P DHT +
Sbjct: 176 ----HLCGFVNR----WNPNV-----------NWFVGGG-SIRN-VHSILPQ-DHTFKSE 213
Query: 784 DGWYLYADSSNGK-FGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKD--NV 840
G Y+Y DS K F + A +++P+ + C ++ G ++ L +D +
Sbjct: 214 LGHYMYVDSVYVKHFQEVAQLISPLTTAPMAGCLSFYYQIQQGND--NVFSLYTRDVAGL 271
Query: 841 TSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSP 900
++W A W AEV +++F G VA+DDISF SP+
Sbjct: 272 YEEIWKADRPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISF---SPV--- 325
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEK 960
HC ++T + C+FE DLC++ Q+K
Sbjct: 326 --------------HC----------------QNQTELLFSAVEASCNFEQDLCNFYQDK 355
Query: 961 DEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSK 1020
+ +K A DHT G G+Y+ + F QP R+ P + +
Sbjct: 356 EGPGWTRVKVK----PNMYRAGDHTTG--LGYYLLANTKFTSQPGYIGRLYGPSLPGNLQ 409
Query: 1021 NCKIIFHYHMYG----NGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDF 1076
C + FHY +YG + A+ + + + Q K+ L +G W + E++
Sbjct: 410 YC-LRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRG-VWMQAEITFKKPMPT 467
Query: 1077 QLKFEGRVGK-GQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYREC 1130
++ F G +ALDDI + S + +P P G C EC
Sbjct: 468 KVVFMSLCKSFWDCGLVALDDITIQLGSCSSSEK------LPPPPGECTFEQDEC 516
Score = 56.6 bits (135), Expect = 2e-07
Identities = 46/170 (27%), Positives = 74/170 (43%), Gaps = 14/170 (8%)
Query: 1435 TTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIG--SRIPAKALIPDSDHTPGSGQ-H 1488
TTG C+FE + C +++W +G S +++P DHT S H
Sbjct: 163 TTGYCIECDFEENH-----LCGFVNRWNPNVNWFVGGGSIRNVHSILPQ-DHTFKSELGH 216
Query: 1489 FLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNIL 1548
++YV+S K S A + C ++Y I + + +YT + +GL
Sbjct: 217 YMYVDSVYVKHFQEVAQLISPLTTAPMAGCLS--FYYQIQQGNDNVFSLYTRDVAGLYEE 274
Query: 1549 VWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTP 1598
+W W V S+ P +V FE +G + ++ALDDISF+P
Sbjct: 275 IWKADRPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSP 324
Score = 51.6 bits (122), Expect = 7e-06
Identities = 43/162 (26%), Positives = 64/162 (39%), Gaps = 11/162 (6%)
Query: 1437 GSCNFETSSGNWTTACSLTQDSEDDLDW-AIGSRIPAKALIPDSDHTPGSGQHFLYVNSS 1495
G C FE C+ TQ+ + W P P DHT G G +++Y+ +S
Sbjct: 507 GECTFEQDE------CTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGVG-YYMYIEAS 559
Query: 1496 GSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTI-EESGLNILVWSVIG 1554
G AR+ + S C +FY + G+L VY EE L+W G
Sbjct: 560 HMVYGQKARLLSRPLRGVSGKHCLT--FFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRG 617
Query: 1555 NKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISF 1596
+ W + S ++ FEA + IA+DD+ F
Sbjct: 618 EQSISWLRALIEYSCERQHQIIFEAIRGVSIRSDIAIDDVKF 659
Score = 38.9 bits (89), Expect = 0.046
Identities = 48/230 (20%), Positives = 88/230 (38%), Gaps = 79/230 (34%)
Query: 988 NSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTN 1047
N GHYI++ + F +Q +A +S + ++ ++++ +T S+++
Sbjct: 47 NEEGHYIYVDTSFGKQGEKAVLLSPDLQAEEWSCLRLVYQ----------ITTSSESLSD 96
Query: 1048 QTKVLLNLTVEQGNF----WRREELS---LFGDED-------FQLKFEGRVGKGQRGDIA 1093
+++ L + E +F W +E S L D F++ EG +G+G IA
Sbjct: 97 PSQLNLYMRFEDESFDRLLWSAKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIA 156
Query: 1094 LDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTD 1153
L +I +T TG+C C+F +N
Sbjct: 157 LFEIKMT-------------------TGYC----------------IECDFEEN------ 175
Query: 1154 ENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRP--PKDHTLGNE 1201
CG+ N N +W +G GS +++ P+DHT +E
Sbjct: 176 ------------HLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSE 213
Score = 37.7 bits (86), Expect = 0.10
Identities = 62/278 (22%), Positives = 105/278 (37%), Gaps = 53/278 (19%)
Query: 1 MSD---VFLFKSKE--EEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFI 55
MSD V++F+ +E W+ S W++A++ + + T K++F S
Sbjct: 424 MSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEITFKKPMPT-KVVFMSLCKS----- 477
Query: 56 ALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT 115
+ CG L + D+ G C + E + +C+ E DE T K
Sbjct: 478 ------FWDCG------LVALDDITIQLGSCSSSEKLPPPPGECTFEQDECTFTQEKR-- 523
Query: 116 CDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAK 175
S W +G + P DHT + G ++Y+EA S V
Sbjct: 524 ---------------NRSSWHRRRGETPTSYTGPKGDHTTGV--GYYMYIEA--SHMVYG 564
Query: 176 LGSPVLTK-LLTASTPCQVQFWYHLSQHSN--LSVFTRTSLDGNLQKQGKIIRFSESQWS 232
+ +L++ L S + F+YH+ LSV+ + D + W
Sbjct: 565 QKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWL 624
Query: 233 HAKIDLIAEAGESTLPFQLILEA-TVLSSNATVALDDI 269
A I+ E Q+I EA +S + +A+DD+
Sbjct: 625 RALIEYSCER-----QHQIIFEAIRGVSIRSDIAIDDV 657
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 1250 PNENTFGSSDHTNW--HFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKAT 1307
P T DHT ++MY+EA+ + + G KA S R S ++F+Y + T
Sbjct: 536 PTSYTGPKGDHTTGVGYYMYIEASHM-VYGQKARLLSRPLRGVSGKHCLTFFYHMYGGGT 594
Query: 1308 GSIQILIKR 1316
G + + +K+
Sbjct: 595 GLLSVYLKK 603
>gi|24111244 MAM domain containing glycosylphosphatidylinositol
anchor 1 [Homo sapiens]
Length = 955
Score = 125 bits (313), Expect = 5e-28
Identities = 81/199 (40%), Positives = 112/199 (56%), Gaps = 21/199 (10%)
Query: 494 TDEVNCAPELQ---CNFETG-ICNWEQDAKDDFDWTR----SQGPTPTLNTGPMKDNTLG 545
T+ +N +P L C+FE IC + QD D+FDWTR +Q P + NTGP D + G
Sbjct: 740 TEPIN-SPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDIS-G 797
Query: 546 TAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWS 605
T +G+Y++IE+S P+ D A L+SP+ NA+ C F+YHM+GK I L + R S
Sbjct: 798 TPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCV-SFFYHMYGKHIGSLNLLVR--S 854
Query: 606 DSRGQL---LWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDC 662
++G L W + GN+GN W + H+ IS PFQI+ E G G+ GDIAIDD+
Sbjct: 855 RNKGALDTHAWSLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDV----- 909
Query: 663 TLYPGNLPADLPTPPETSV 681
TL G P P + V
Sbjct: 910 TLKKGECPRKQTDPNKVVV 928
Score = 85.5 bits (210), Expect = 4e-16
Identities = 55/167 (32%), Positives = 89/167 (53%), Gaps = 14/167 (8%)
Query: 943 SSGRCDFEFD-LCSWKQEKDEDFDWN----LKASSIPAAGTEPAADHTLGNSSGHYIFIK 997
S C FE + +C + Q+ ++FDW L + + T P D + G G+Y+FI+
Sbjct: 749 SDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDIS-GTPEGYYMFIE 807
Query: 998 SLFPQQPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLL---- 1053
+ P++ AR+ SP+ + +K + F YHMYG IG+L L+ V ++ K L
Sbjct: 808 TSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLL---VRSRNKGALDTHA 864
Query: 1054 -NLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVL 1099
+L+ +GN W++ + + FQ+ FEG G G GDIA+DD+ L
Sbjct: 865 WSLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDVTL 911
Score = 79.7 bits (195), Expect = 2e-14
Identities = 42/167 (25%), Positives = 85/167 (50%), Gaps = 11/167 (6%)
Query: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY 789
C FE +C + Q + ++ F W N ++ + + T +G+Y++
Sbjct: 753 CHFEDEKICGYTQDL-------TDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMF 805
Query: 790 ADSSNGK-FGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDN---VTSKLW 845
++S + GD A +++P+ + + + F+ HM G +GSL +L++ N + + W
Sbjct: 806 IETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAW 865
Query: 846 AQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQ 892
+ +G +G W++A V + QI+F RG Y+GD+A+DD++ +
Sbjct: 866 SLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDVTLK 912
Score = 59.3 bits (142), Expect = 3e-08
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 5/178 (2%)
Query: 283 PRTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQ-SELSADFEHQAPPRDHSLNASQ 341
P S + C FE + D+FDW R + ++ + PP D S +
Sbjct: 742 PINSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDIS-GTPE 800
Query: 342 GHFMFI-LKKSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHD- 399
G++MFI + L A+L SP ++ + +SF+++ YG +G+ L + N
Sbjct: 801 GYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGAL 860
Query: 400 STVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLP 457
T W + N+G W +A + + S PF + + V Y G AIDD+ + P
Sbjct: 861 DTHAWSLSGNKGNVWQQAHVPISP-SGPFQIIFEGVRGPGYLGDIAIDDVTLKKGECP 917
Score = 58.5 bits (140), Expect = 6e-08
Identities = 54/209 (25%), Positives = 87/209 (41%), Gaps = 33/209 (15%)
Query: 1431 HYTSTTGSCNFETSSGNWTTA--CSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQ- 1487
HYT S N ++ ++ C TQD D+ DW AL + +P +G
Sbjct: 738 HYTEPINSPNLSDNTCHFEDEKICGYTQDLTDNFDWT-----RQNALTQNPKRSPNTGPP 792
Query: 1488 ---------HFLYVNSSGSKE-GSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGI-LK 1536
+++++ +S +E G AR+ S + AS V F+++M + L
Sbjct: 793 TDISGTPEGYYMFIETSRPRELGDRARLV-SPLYNASAKFYCVSFFYHMYGKHIGSLNLL 851
Query: 1537 VYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISF 1596
V + + L+ WS+ GNK W VP+S + PF++ FE IA+DD++
Sbjct: 852 VRSRNKGALDTHAWSLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDVTL 911
Query: 1597 TP-EC------------VTGGPVPVQPSP 1612
EC + G P Q SP
Sbjct: 912 KKGECPRKQTDPNKVVVMPGSGAPCQSSP 940
Score = 32.7 bits (73), Expect = 3.3
Identities = 14/52 (26%), Positives = 30/52 (57%)
Query: 1264 HFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIK 1315
++M++E + GD+A S ++ S+ +SF+Y + K GS+ +L++
Sbjct: 802 YYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVR 853
>gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]
Length = 956
Score = 116 bits (291), Expect = 2e-25
Identities = 72/178 (40%), Positives = 97/178 (54%), Gaps = 24/178 (13%)
Query: 502 ELQCNFETG-ICNWEQDAKDDFDWTRSQGPTP----TLNTGPMKDNTLGTAKGHYLYIES 556
E C FE G IC + QD D+FDWT+ T T NTGP D + G+ +G Y+YIE+
Sbjct: 745 EFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIET 803
Query: 557 SEPQAFQDSAALLSPILNA--------TDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSR 608
S P+ + A LLSP+ + T+T C F F+YHM+G+ I L +Y R+ +
Sbjct: 804 SRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYC-FSFFYHMYGQHIGVLNVYLRL----K 858
Query: 609 GQL-----LWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMD 661
GQ LW GN+G RW H+NI FQ++ E G G GDIAIDD+S +
Sbjct: 859 GQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAE 916
Score = 78.6 bits (192), Expect = 5e-14
Identities = 55/172 (31%), Positives = 87/172 (50%), Gaps = 20/172 (11%)
Query: 947 CDFEF-DLCSWKQEKDEDFDWNLKASSIP----AAGTEPAADHTLGNSSGHYIFIKSLFP 1001
C FE ++C + Q+ ++FDW ++++ T P AD + G+ G Y++I++ P
Sbjct: 748 CGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIETSRP 806
Query: 1002 QQPMRAARISSPVISKRSKN---------CKIIFHYHMYGNGIGALTLMQVSVTNQTKV- 1051
+ AR+ SPV S KN C F YHMYG IG L + + + QT +
Sbjct: 807 RLEGEKARLLSPVFSIAPKNPYGPTNTAYC-FSFFYHMYGQHIGVLNVY-LRLKGQTTIE 864
Query: 1052 --LLNLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLTE 1101
L + + +G W ++++ FQL FEG G G GDIA+DD+ + E
Sbjct: 865 NPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAE 916
Score = 69.3 bits (168), Expect = 3e-11
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 21/177 (11%)
Query: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHG-EENHRPSVDHTQNTTDGWYL 788
C FE ++C + Q D++ F W + + + N P+ D + + +G+Y+
Sbjct: 748 CGFEDGNICLFTQ-------DDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYM 799
Query: 789 YADSSNGKF-GDTADILTPIISLT-----GPKCTLV---FWTHMNGATVGSLQVLIK--- 836
Y ++S + G+ A +L+P+ S+ GP T F+ HM G +G L V ++
Sbjct: 800 YIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKG 859
Query: 837 KDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQD 893
+ + + LW+ +G +G +W A V + + Q++F RG GD+A+DD+S +
Sbjct: 860 QTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAE 916
Score = 55.1 bits (131), Expect = 6e-07
Identities = 40/166 (24%), Positives = 71/166 (42%), Gaps = 11/166 (6%)
Query: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
C FE + F D+FDW + S + + + P + +G +M+I
Sbjct: 748 CGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPR 807
Query: 354 L-WQVAKLQSPTFS--------QTGPGCILSFWFYNYGLSVGAAELQLHMENSHD-STVI 403
L + A+L SP FS T SF+++ YG +G + L ++ +
Sbjct: 808 LEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPL 867
Query: 404 WRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDI 449
W N+G++W EA + + ++ F L + + +G AIDD+
Sbjct: 868 WSSSGNKGQRWNEAHVNIYPITS-FQLIFEGIRGPGIEGDIAIDDV 912
Score = 47.0 bits (110), Expect = 2e-04
Identities = 47/179 (26%), Positives = 74/179 (41%), Gaps = 24/179 (13%)
Query: 1439 CNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALI-----PDSDHTPGSGQHFLYVN 1493
C FE GN C TQD D+ DW S P++D + ++Y+
Sbjct: 748 CGFE--DGN---ICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIE 802
Query: 1494 SSGSK-EGSVARITT--------SKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESG 1544
+S + EG AR+ + + P + C +FY + + +G+L VY +
Sbjct: 803 TSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFS--FFYHMYGQHIGVLNVYLRLKGQ 860
Query: 1545 LNIL--VWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTP-EC 1600
I +WS GNK W V + + F++ FE + IA+DD+S EC
Sbjct: 861 TTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 919
>gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens]
Length = 727
Score = 116 bits (291), Expect = 2e-25
Identities = 72/178 (40%), Positives = 97/178 (54%), Gaps = 24/178 (13%)
Query: 502 ELQCNFETG-ICNWEQDAKDDFDWTRSQGPTP----TLNTGPMKDNTLGTAKGHYLYIES 556
E C FE G IC + QD D+FDWT+ T T NTGP D + G+ +G Y+YIE+
Sbjct: 516 EFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIET 574
Query: 557 SEPQAFQDSAALLSPILNA--------TDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSR 608
S P+ + A LLSP+ + T+T C F F+YHM+G+ I L +Y R+ +
Sbjct: 575 SRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYC-FSFFYHMYGQHIGVLNVYLRL----K 629
Query: 609 GQL-----LWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMD 661
GQ LW GN+G RW H+NI FQ++ E G G GDIAIDD+S +
Sbjct: 630 GQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAE 687
Score = 78.6 bits (192), Expect = 5e-14
Identities = 55/172 (31%), Positives = 87/172 (50%), Gaps = 20/172 (11%)
Query: 947 CDFEF-DLCSWKQEKDEDFDWNLKASSIP----AAGTEPAADHTLGNSSGHYIFIKSLFP 1001
C FE ++C + Q+ ++FDW ++++ T P AD + G+ G Y++I++ P
Sbjct: 519 CGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIETSRP 577
Query: 1002 QQPMRAARISSPVISKRSKN---------CKIIFHYHMYGNGIGALTLMQVSVTNQTKV- 1051
+ AR+ SPV S KN C F YHMYG IG L + + + QT +
Sbjct: 578 RLEGEKARLLSPVFSIAPKNPYGPTNTAYC-FSFFYHMYGQHIGVLNVY-LRLKGQTTIE 635
Query: 1052 --LLNLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLTE 1101
L + + +G W ++++ FQL FEG G G GDIA+DD+ + E
Sbjct: 636 NPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAE 687
Score = 69.3 bits (168), Expect = 3e-11
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 21/177 (11%)
Query: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHG-EENHRPSVDHTQNTTDGWYL 788
C FE ++C + Q D++ F W + + + N P+ D + + +G+Y+
Sbjct: 519 CGFEDGNICLFTQ-------DDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYM 570
Query: 789 YADSSNGKF-GDTADILTPIISLT-----GPKCTLV---FWTHMNGATVGSLQVLIK--- 836
Y ++S + G+ A +L+P+ S+ GP T F+ HM G +G L V ++
Sbjct: 571 YIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKG 630
Query: 837 KDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQD 893
+ + + LW+ +G +G +W A V + + Q++F RG GD+A+DD+S +
Sbjct: 631 QTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAE 687
Score = 55.1 bits (131), Expect = 6e-07
Identities = 40/166 (24%), Positives = 71/166 (42%), Gaps = 11/166 (6%)
Query: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
C FE + F D+FDW + S + + + P + +G +M+I
Sbjct: 519 CGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPR 578
Query: 354 L-WQVAKLQSPTFS--------QTGPGCILSFWFYNYGLSVGAAELQLHMENSHD-STVI 403
L + A+L SP FS T SF+++ YG +G + L ++ +
Sbjct: 579 LEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPL 638
Query: 404 WRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDI 449
W N+G++W EA + + ++ F L + + +G AIDD+
Sbjct: 639 WSSSGNKGQRWNEAHVNIYPITS-FQLIFEGIRGPGIEGDIAIDDV 683
Score = 47.0 bits (110), Expect = 2e-04
Identities = 47/179 (26%), Positives = 74/179 (41%), Gaps = 24/179 (13%)
Query: 1439 CNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALI-----PDSDHTPGSGQHFLYVN 1493
C FE GN C TQD D+ DW S P++D + ++Y+
Sbjct: 519 CGFE--DGN---ICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIE 573
Query: 1494 SSGSK-EGSVARITT--------SKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESG 1544
+S + EG AR+ + + P + C +FY + + +G+L VY +
Sbjct: 574 TSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFS--FFYHMYGQHIGVLNVYLRLKGQ 631
Query: 1545 LNIL--VWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTP-EC 1600
I +WS GNK W V + + F++ FE + IA+DD+S EC
Sbjct: 632 TTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 690
>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
Length = 4655
Score = 100 bits (248), Expect = 2e-20
Identities = 99/349 (28%), Positives = 136/349 (38%), Gaps = 45/349 (12%)
Query: 1398 TDFLC-RDKKCIASHLLCDYKPDCSDRSDE-AHCAHYTSTTGSCNFETSSGNWTTACSLT 1455
T FLC ++KCI CD + DCSD SDE A C G F+ S GN T+ +L
Sbjct: 3515 TQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQ--FQCSDGNCTSPQTLC 3572
Query: 1456 QDSEDDLDWAIGSRIPAKALIPDSDH--------TPGSGQHFLYV----NSSGSKEGSVA 1503
++ D + R+ + DS+ P S Q + NS +
Sbjct: 3573 NAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCAS 3632
Query: 1504 RITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYG 1563
R F + G C + W +D G IEE + + Y
Sbjct: 3633 RTCRPGQFRCANGRCIPQAWKCDVD-NDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 1564 SVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYT 1623
+P A +G +D D S C PV C+
Sbjct: 3692 CIPKW----------AVCNGVDDC----RDNSDEQGCEERTCHPVGDFRCKNHH------ 3731
Query: 1624 LQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCH 1683
C+PL +CDG DC D SDE +C P C+ EF C +CIPS +CD DC
Sbjct: 3732 --CIPLRWQCDGQNDCGDNSDEENC----APRECTESEFRCVNQQCIPSRWICDHYNDCG 3785
Query: 1684 FNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
N DE C ++C C S + C+ + +CDG ADC+D DE+ C
Sbjct: 3786 DNSDERDCEMRTCHPEYFQCTSGH-CVHSELKCDGSADCLDAS-DEADC 3832
Score = 92.8 bits (229), Expect = 3e-18
Identities = 62/178 (34%), Positives = 81/178 (45%), Gaps = 22/178 (12%)
Query: 1593 DISFT----PECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDC 1648
D+SF +CV G C A QF C +C+ ++ +CDG DC D SDE C
Sbjct: 1163 DLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGC 1222
Query: 1649 PLSPTPPLCSNMEFPCSTDE-CIPSLLLCDGVPDCHFNEDE-LICSNKSCSNGALVCASS 1706
P P P +C + EF C D CIP+ CDG PDC + DE C K+C + C +
Sbjct: 1223 PTRP-PGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTCPSSYFHCDNG 1281
Query: 1707 NSCIPAHQRCDGFADCMDFQLDESSC--------SDTWTLLGIGLAFLMTHITVAVLC 1756
N CI CD DC D DE C S W LG + + ++V+C
Sbjct: 1282 N-CIHRAWLCDRDNDCGDMS-DEKDCPTQPFRCPSWQWQCLGHNIC-----VNLSVVC 1332
Score = 88.2 bits (217), Expect = 7e-17
Identities = 47/124 (37%), Positives = 64/124 (51%), Gaps = 10/124 (8%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPC-STDECIP 1671
C+ QF+C +C+ LS CDG +DC+DGSDE+ C L+ C+ +F C S D+CI
Sbjct: 1149 CQPSQFNCP-NHRCIDLSFVCDGDKDCVDGSDEVGCVLN-----CTASQFKCASGDKCIG 1202
Query: 1672 SLLLCDGVPDCHFNEDELICSNK---SCSNGALVCASSNSCIPAHQRCDGFADCMDFQLD 1728
CDGV DC N DE C + C + C CIP CDG DC+ +
Sbjct: 1203 VTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDE 1262
Query: 1729 ESSC 1732
++C
Sbjct: 1263 HNAC 1266
Score = 86.7 bits (213), Expect = 2e-16
Identities = 46/122 (37%), Positives = 62/122 (50%), Gaps = 8/122 (6%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMD-CPLSPTPPLCSNMEFPCSTDECIP 1671
C + QF C +C+P+ KCDG +DC DGSDE+ CP C +F CS C
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCP----QRFCRLGQFQCSDGNCTS 3567
Query: 1672 SLLLCDGVPDC--HFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDE 1729
LC+ +C +ED L+C N C + CA+ CIP +CD F DC D ++
Sbjct: 3568 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKR-CIPESWQCDTFNDCEDNSDED 3626
Query: 1730 SS 1731
SS
Sbjct: 3627 SS 3628
Score = 85.9 bits (211), Expect = 3e-16
Identities = 45/114 (39%), Positives = 59/114 (51%), Gaps = 6/114 (5%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C F+C +CV S +CD + DC DGSDE C + EF C+ CIP
Sbjct: 2741 CSPTAFTCANG-RCVQYSYRCDYYNDCGDGSDEAGCLFRDCN---ATTEFMCNNRRCIPR 2796
Query: 1673 LLLCDGVPDCHFNE--DELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
+C+GV +CH N DE C +++C +G C +SN CIP CDG DC D
Sbjct: 2797 EFICNGVDNCHDNNTSDEKNCPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGD 2850
Score = 84.0 bits (206), Expect = 1e-15
Identities = 43/96 (44%), Positives = 52/96 (54%), Gaps = 8/96 (8%)
Query: 1643 SDEMDCPLSPT--PPL--CSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICS--NKSC 1696
S+ + C PT PP C FPC C+P+ LCDGV DCH N DE +C N +C
Sbjct: 1008 SNHLTCEGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTC 1067
Query: 1697 SNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
S+ A C CIPAH RCD DC+D DE +C
Sbjct: 1068 SSSAFTC-GHGECIPAHWRCDKRNDCVDGS-DEHNC 1101
Score = 83.6 bits (205), Expect = 2e-15
Identities = 48/123 (39%), Positives = 61/123 (49%), Gaps = 9/123 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE-MDCPLSPTPPLCSNMEFPCSTDECIP 1671
C+ F C QC+P S CD +DC DGSDE DC S CS+ + CS +CIP
Sbjct: 67 CQQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDERQDCSQST----CSSHQITCSNGQCIP 122
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
S CD V DC DE C +C L C + +C Q+CD DC D DE +
Sbjct: 123 SEYRCDHVRDCPDGADENDCQYPTCEQ--LTC-DNGACYNTSQKCDWKVDCRD-SSDEIN 178
Query: 1732 CSD 1734
C++
Sbjct: 179 CTE 181
Score = 83.6 bits (205), Expect = 2e-15
Identities = 47/123 (38%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNM-EFPCSTD-ECI 1670
C QF C +C+P + KCD DC D SDE + LC N EF C T+ CI
Sbjct: 3635 CRPGQFRCANG-RCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCI 3693
Query: 1671 PSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDES 1730
P +C+GV DC N DE C ++C ++ CIP +CDG DC D DE
Sbjct: 3694 PKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGD-NSDEE 3752
Query: 1731 SCS 1733
+C+
Sbjct: 3753 NCA 3755
Score = 82.4 bits (202), Expect = 4e-15
Identities = 45/128 (35%), Positives = 65/128 (50%), Gaps = 9/128 (7%)
Query: 1607 PVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCST 1666
P C++ F C + C+P +CDG +DC D +DE+ C + C F C +
Sbjct: 22 PASGQECDSAHFRC-GSGHCIPADWRCDGTKDCSDDADEIGCAVVT----CQQGYFKCQS 76
Query: 1667 D-ECIPSLLLCDGVPDCHFNEDELI-CSNKSCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
+ +CIP+ +CD DC DE CS +CS+ + C S+ CIP+ RCD DC D
Sbjct: 77 EGQCIPNSWVCDQDQDCDDGSDERQDCSQSTCSSHQITC-SNGQCIPSEYRCDHVRDCPD 135
Query: 1725 FQLDESSC 1732
DE+ C
Sbjct: 136 -GADENDC 142
Score = 80.9 bits (198), Expect = 1e-14
Identities = 43/115 (37%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLS-PTPPLCSNMEFPCSTDECIP 1671
C + F C + CV KCDG DC+D SDE DCP P C F C CIP
Sbjct: 3798 CHPEYFQCT-SGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIP 3856
Query: 1672 SLLLCDGVPDCHFNEDE--LICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
CDG DC DE +C + C++ +N CI +H+ C+G DC D
Sbjct: 3857 PYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGD 3911
Score = 79.3 bits (194), Expect = 3e-14
Identities = 42/121 (34%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C + F+C + +C+P +CD DC+DGSDE +CP + P C + ++ C +CI
Sbjct: 1067 CSSSAFTCGHG-ECIPAHWRCDKRNDCVDGSDEHNCP-THAPASCLDTQYTCDNHQCISK 1124
Query: 1673 LLLCDGVPDCHFNEDELIC-SNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
+CD DC DE C S ++C C + + CI CDG DC+D DE
Sbjct: 1125 NWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPN-HRCIDLSFVCDGDKDCVDGS-DEVG 1182
Query: 1732 C 1732
C
Sbjct: 1183 C 1183
Score = 76.6 bits (187), Expect = 2e-13
Identities = 43/128 (33%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C + +F C + +C+P CD DC D SDE + C EF C CIPS
Sbjct: 2864 CSSSEFQCA-SGRCIPQHWYCDQETDCFDASDE-PASCGHSERTCLADEFKCDGGRCIPS 2921
Query: 1673 LLLCDGVPDCHFNEDE---LICSNKSCSNGALVCASSNS----CIPAHQRCDGFADCMDF 1725
+CDG DC DE C N++CS+ +C + CIP CDG DC D
Sbjct: 2922 EWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDG 2981
Query: 1726 QLDESSCS 1733
+ +C+
Sbjct: 2982 YDENQNCT 2989
Score = 76.3 bits (186), Expect = 3e-13
Identities = 47/134 (35%), Positives = 57/134 (42%), Gaps = 16/134 (11%)
Query: 1608 VQPSPCEADQFSCIYTL---------QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCS 1658
V+ P AD+ C Y C S KCD DC D SDE++C +C
Sbjct: 130 VRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCT-----EICL 184
Query: 1659 NMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDG 1718
+ EF C ECIP +CD DC DE C+ +C C S CI + CDG
Sbjct: 185 HNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFTCPSGR-CIYQNWVCDG 243
Query: 1719 FADCMDFQLDESSC 1732
DC D DE C
Sbjct: 244 EDDCKD-NGDEDGC 256
Score = 76.3 bits (186), Expect = 3e-13
Identities = 42/120 (35%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDEC 1669
P C +F C+ QC+P CD + DC D SDE DC + C F C++ C
Sbjct: 3756 PRECTESEFRCV-NQQCIPSRWICDHYNDCGDNSDERDCEMR----TCHPEYFQCTSGHC 3810
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNK-----SCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
+ S L CDG DC DE C + C C ++ CIP + +CDG DC D
Sbjct: 3811 VHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFEC-KNHVCIPPYWKCDGDDDCGD 3869
Score = 75.9 bits (185), Expect = 3e-13
Identities = 42/115 (36%), Positives = 53/115 (46%), Gaps = 10/115 (8%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C ++FSC +C+P + CD DC DGSDE C P C +F C + CI
Sbjct: 183 CLHNEFSC-GNGECIPRAYVCDHDNDCQDGSDEHACNY----PTCGGYQFTCPSGRCIYQ 237
Query: 1673 LLLCDGVPDCHFNEDELICSN-----KSCSNGALVCASSNSCIPAHQRCDGFADC 1722
+CDG DC N DE C + CS C S CI ++ CDG DC
Sbjct: 238 NWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDC 292
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/126 (38%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE---- 1668
C AD+F C +C+P CDG DC D SDE D CS+ EF C D
Sbjct: 2906 CLADEFKCDGG-RCIPSEWICDGDNDCGDMSDE-DKRHQCQNQNCSDSEFLCVNDRPPDR 2963
Query: 1669 -CIPSLLLCDGVPDCHFNEDE-LICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQ 1726
CIP +CDG DC DE C+ ++CS C CIP RCD DC D+
Sbjct: 2964 RCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGYG-LCIPKIFRCDRHNDCGDYS 3022
Query: 1727 LDESSC 1732
DE C
Sbjct: 3023 -DERGC 3027
Score = 73.2 bits (178), Expect = 2e-12
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 16/161 (9%)
Query: 1578 EADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHE 1637
E DG+ D A D+ +C T P + C+A F C + C+P KCDG +
Sbjct: 3814 ELKCDGSADCLDASDEA----DCPTRFP---DGAYCQATMFECKNHV-CIPPYWKCDGDD 3865
Query: 1638 DCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDEL--IC---S 1692
DC DGSDE + L P S F C + CI S +C+GV DC DE C +
Sbjct: 3866 DCGDGSDE-ELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPT 3924
Query: 1693 NKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCS 1733
K C+ C + + CIP CD DC D+ DE C+
Sbjct: 3925 PKPCTEYEYKCGNGH-CIPHDNVCDDADDCGDWS-DELGCN 3963
Score = 72.0 bits (175), Expect = 5e-12
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 13/133 (9%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C++ C + C+P CDG DC D SDE P T CS+ EF C++ CIP
Sbjct: 2822 CQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDEN--PTYCTTHTCSSSEFQCASGRCIPQ 2879
Query: 1673 LLLCDGVPDCHFNEDELIC---SNKSCSNGALVCASSNSCIPAHQRCDGFADCMDF---- 1725
CD DC DE S ++C C CIP+ CDG DC D
Sbjct: 2880 HWYCDQETDCFDASDEPASCGHSERTCLADEFKC-DGGRCIPSEWICDGDNDCGDMSDED 2938
Query: 1726 ---QLDESSCSDT 1735
Q +CSD+
Sbjct: 2939 KRHQCQNQNCSDS 2951
Score = 70.9 bits (172), Expect = 1e-11
Identities = 42/125 (33%), Positives = 55/125 (44%), Gaps = 8/125 (6%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMD--CPLSPTPPLCSNMEFPCSTDECI 1670
C A F+C +C+ KCD DC DGSDEM+ C L CS F C+ C+
Sbjct: 2700 CGASSFTCSNG-RCISEEWKCDNDNDCGDGSDEMESVCALHT----CSPTAFTCANGRCV 2754
Query: 1671 PSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQL-DE 1729
CD DC DE C + C+ ++ CIP C+G +C D DE
Sbjct: 2755 QYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDE 2814
Query: 1730 SSCSD 1734
+C D
Sbjct: 2815 KNCPD 2819
Score = 68.6 bits (166), Expect = 5e-11
Identities = 42/121 (34%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 1609 QPSPCEADQFSCIYTL----QCVPLSGKCDGHEDCIDGSDE-MDCPLSPTPPLCSNMEFP 1663
Q C +F C+ +C+P S CDG DC DG DE +C T CS EF
Sbjct: 2944 QNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNC----TRRTCSENEFT 2999
Query: 1664 CSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCM 1723
C CIP + CD DC DE C ++C C + CI CD DC
Sbjct: 3000 CGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTC-QNGRCISKTFVCDEDNDCG 3058
Query: 1724 D 1724
D
Sbjct: 3059 D 3059
Score = 67.0 bits (162), Expect = 2e-10
Identities = 51/140 (36%), Positives = 64/140 (45%), Gaps = 11/140 (7%)
Query: 1603 GGPVPVQPSP-CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDC-PLSPTPPLCSNM 1660
G P P+ C F C +CVP CDG +DC D SDE C L+ T CS+
Sbjct: 1015 GDPTNEPPTEQCGLFSFPC-KNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNT---CSSS 1070
Query: 1661 EFPCSTDECIPSLLLCDGVPDCHFNEDELIC---SNKSCSNGALVCASSNSCIPAHQRCD 1717
F C ECIP+ CD DC DE C + SC + C ++ CI + CD
Sbjct: 1071 AFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTC-DNHQCISKNWVCD 1129
Query: 1718 GFADCMDFQLDESSCSDTWT 1737
DC D DE +C+ T T
Sbjct: 1130 TDNDCGDGS-DEKNCNSTET 1148
Score = 63.2 bits (152), Expect = 2e-09
Identities = 28/79 (35%), Positives = 37/79 (46%)
Query: 1657 CSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRC 1716
C + F C + CIP+ CDG DC + DE+ C+ +C G C S CIP C
Sbjct: 28 CDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSEGQCIPNSWVC 87
Query: 1717 DGFADCMDFQLDESSCSDT 1735
D DC D + CS +
Sbjct: 88 DQDQDCDDGSDERQDCSQS 106
Score = 63.2 bits (152), Expect = 2e-09
Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 11/122 (9%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C+ +QF+C +C+ + CD DC DGSDE+ P C EF C CI
Sbjct: 3032 CQQNQFTC-QNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEM 3090
Query: 1673 LLLCDGVPDCHFNEDELICSNKSCSNGALVCASSN----------SCIPAHQRCDGFADC 1722
+ LC+ + DC N DE C C + ++ N SC P ++ C
Sbjct: 3091 MKLCNHLDDCLDNSDEKGCGINECHDPSISGCDHNCTDTLTSFYCSCRPGYKLMSDKRTC 3150
Query: 1723 MD 1724
+D
Sbjct: 3151 VD 3152
Score = 57.0 bits (136), Expect = 2e-07
Identities = 70/285 (24%), Positives = 98/285 (34%), Gaps = 42/285 (14%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSL-CKWYQPI 744
P C +F C SDG+C C+ +CPD SDE + E + C + I
Sbjct: 3549 PQRFCRLGQFQC-SDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCI 3607
Query: 745 PVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQN---TTDGWYLYADSSNGKFGDT- 800
P D+ + S H RP N W D+ G D
Sbjct: 3608 PESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEP 3667
Query: 801 ----------ADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQ 850
D T T +C + W NG V +DN + +
Sbjct: 3668 IEECMSSAHLCDNFTEFSCKTNYRC-IPKWAVCNG-------VDDCRDN--------SDE 3711
Query: 851 QGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFM 910
QG + + R + D D+ ++C+P R+CT+ EF
Sbjct: 3712 QGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCG-DNSDEENCAP-----RECTESEFR 3765
Query: 911 CANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCS 955
C N+ CI +CD NDC DNSDE RT C E+ C+
Sbjct: 3766 CVNQQCIPSRWICDHYNDCGDNSDERDCEMRT----CHPEYFQCT 3806
Score = 53.9 bits (128), Expect = 1e-06
Identities = 68/275 (24%), Positives = 97/275 (35%), Gaps = 28/275 (10%)
Query: 688 HNCTD-NEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV 746
H C + EF C+++ CI K C+ DC D SDE C C CK + IP+
Sbjct: 3676 HLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPL 3735
Query: 747 HLLQDSNTFRWGLGNGISIHHGEENHRPS--------VDHTQNTTDGWYLYADSSNGKFG 798
D N + EEN P + Q W + G
Sbjct: 3736 RWQCDGQ-------NDCGDNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNS 3788
Query: 799 DTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRA 858
D D +CT H GS L D T + +A
Sbjct: 3789 DERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEAD----CPTRFPDGAYCQA 3844
Query: 859 EVFLGIRSHTQIVFRAK-RGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCI 917
+F ++H I K G GD + +++ P SP R F C N CI
Sbjct: 3845 TMF-ECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNR------FRCDNNRCI 3897
Query: 918 AKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFD 952
++C+ V+DC D +DET CR + + E++
Sbjct: 3898 YSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYE 3932
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPP-LCSNMEFPC-STDECI 1670
C QF+C + +C+ + CDG +DC D DE C P CS E+ C + CI
Sbjct: 222 CGGYQFTCP-SGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCI 280
Query: 1671 PSLLLCDGVPDCHFNEDELICS-NKSCSNGALVCASSNSCIPAHQ 1714
+CDG+ DC EDE S K CS +C++ N H+
Sbjct: 281 SIYKVCDGILDCPGREDENNTSTGKYCS--MTLCSALNCQYQCHE 323
Score = 53.1 bits (126), Expect = 2e-06
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 18/127 (14%)
Query: 1607 PVQPSPCEADQFSCIYTLQCVPLSGK---CDGHED--CIDGSDEMDCPLSPTPPLCSNME 1661
P+ +PC + C + P GK C+ +D + S C P+CS+ +
Sbjct: 3463 PIVSNPCGTNNGGCSHLCLIKP-GGKGFTCECPDDFRTLQLSGSTYCM-----PMCSSTQ 3516
Query: 1662 FPCSTDE-CIPSLLLCDGVPDCHFNEDEL-ICSNKSCSNGALVCASSNSCIP-----AHQ 1714
F C+ +E CIP CDG DC DEL +C + C G C+ N P AHQ
Sbjct: 3517 FLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNAHQ 3576
Query: 1715 RCDGFAD 1721
C +D
Sbjct: 3577 NCPDGSD 3583
Score = 53.1 bits (126), Expect = 2e-06
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 14/77 (18%)
Query: 897 LLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC----------RTSSGR 946
LL C +E+ CANK CI + CD NDC DNSDE + C R ++GR
Sbjct: 3587 LLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGR 3646
Query: 947 CDFEFDLCSWKQEKDED 963
C + +WK + D D
Sbjct: 3647 CIPQ----AWKCDVDND 3659
Score = 52.4 bits (124), Expect = 4e-06
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 64 ACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
+CG S + C ADEF C G+CI E +CD DC D SDED ++ C C
Sbjct: 2898 SCGH--SERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLC 2955
Score = 48.9 bits (115), Expect = 4e-05
Identities = 20/37 (54%), Positives = 24/37 (64%)
Query: 899 SPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
+PE C HEF C N CI KLC+ ++DC DNSDE
Sbjct: 3070 TPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDE 3106
Score = 48.5 bits (114), Expect = 6e-05
Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
C A F C++G+CI++E CD+ DC D SDE + C+ H TC
Sbjct: 2700 CGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALH-TC 2741
Score = 48.1 bits (113), Expect = 8e-05
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 688 HNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIP 745
H C+ F C ++G C++ +CD+ DC D SDEA C+ C+ +C + IP
Sbjct: 2739 HTCSPTAFTC-ANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNRRCIP 2795
Score = 48.1 bits (113), Expect = 8e-05
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRC 947
C ++F C N CI+K +CD NDC D SDE +C T C
Sbjct: 3032 CQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTC 3075
Score = 47.0 bits (110), Expect = 2e-04
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
++ C +F C+ G C + +++C++ Q+C D SDED C H CD C
Sbjct: 3550 QRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENH-HCDSNEWQC 3601
Score = 47.0 bits (110), Expect = 2e-04
Identities = 17/34 (50%), Positives = 23/34 (67%)
Query: 902 RKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
+ CT++E+ C N HCI D +CD +DC D SDE
Sbjct: 3926 KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDE 3959
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 11/80 (13%)
Query: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE------TTFICRTSSG 945
QDCS + C+ H+ C+N CI + CD V DC D +DE T +G
Sbjct: 101 QDCS-----QSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNG 155
Query: 946 RCDFEFDLCSWKQEKDEDFD 965
C C WK + + D
Sbjct: 156 ACYNTSQKCDWKVDCRDSSD 175
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 6/60 (10%)
Query: 67 QTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCSKHLTCDFESGFC 123
Q S+ CS+ + C++GQCI E CD +DC D +DE+ TC + LTCD +G C
Sbjct: 101 QDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTC-EQLTCD--NGAC 157
Score = 46.6 bits (109), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATC 110
CS+ EF C SG+CI + CD DC D SDE PA+C
Sbjct: 2864 CSSSEFQCASGRCIPQHWYCDQETDCFDASDE-PASC 2899
Score = 45.4 bits (106), Expect = 5e-04
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 16/89 (17%)
Query: 889 ISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT----------F 938
+ +D S ++ C +EF C N CI + +CD NDC D SDE F
Sbjct: 168 VDCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQF 227
Query: 939 ICRTSSGRCDFEFDLC----SWKQEKDED 963
C SGRC ++ +C K DED
Sbjct: 228 TC--PSGRCIYQNWVCDGEDDCKDNGDED 254
Score = 45.1 bits (105), Expect = 6e-04
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 63 YACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCSKH-LTCDF 118
Y Q +R+ CS +EF C G CI K CD DC D SDE TC ++ TC
Sbjct: 2982 YDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTC-- 3039
Query: 119 ESGFCGWEPFLTEDSH 134
++G C + F+ ++ +
Sbjct: 3040 QNGRCISKTFVCDEDN 3055
Score = 45.1 bits (105), Expect = 6e-04
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 1102 NCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECG 1158
+C D + P PT CP +C NG+C + + CN +D+C DN+DE CG
Sbjct: 3056 DCGDGSDELMHLCHTPEPT--CPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGCG 3110
Score = 44.7 bits (104), Expect = 8e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----TTFICRTSSGRC 947
C D ++ C N CI+K+ +CD NDC D SDE +T C+ S C
Sbjct: 1109 CLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNC 1156
Score = 44.7 bits (104), Expect = 8e-04
Identities = 18/37 (48%), Positives = 22/37 (59%)
Query: 689 NCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
NCT ++F C S CI +CD +DC D SDEA C
Sbjct: 1186 NCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGC 1222
Score = 44.3 bits (103), Expect = 0.001
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%)
Query: 902 RKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---TTFICRTSSGRCDFEFDLC--SW 956
++C F C + HCI D CD DC+D++DE C+ +C E SW
Sbjct: 26 QECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSEGQCIPNSW 85
Query: 957 KQEKDEDFD 965
++D+D D
Sbjct: 86 VCDQDQDCD 94
Score = 43.9 bits (102), Expect = 0.001
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 10/72 (13%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCS---- 955
P +C F C N C+ LCD V+DC DNSDE +C T + C C
Sbjct: 1022 PTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQ--LCGTLNNTCSSSAFTCGHGEC 1079
Query: 956 ----WKQEKDED 963
W+ +K D
Sbjct: 1080 IPAHWRCDKRND 1091
Score = 43.9 bits (102), Expect = 0.001
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C++NEF C G CI K+ +CD DC D SDE C+ + C
Sbjct: 2993 CSENEFTC-GYGLCIPKIFRCDRHNDCGDYSDERGCLYQTC 3032
Score = 43.9 bits (102), Expect = 0.001
Identities = 19/45 (42%), Positives = 24/45 (53%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
K C+ E+ C +G CI ++VCD DC D SDE K TC
Sbjct: 3926 KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTC 3970
Score = 43.5 bits (101), Expect = 0.002
Identities = 24/49 (48%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Query: 74 CSADEFPCTS-GQCIAKESVCDSRQDCSDESDE----DPATCSKH-LTC 116
C F C S GQCI VCD QDC D SDE +TCS H +TC
Sbjct: 67 CQQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDERQDCSQSTCSSHQITC 115
Score = 43.5 bits (101), Expect = 0.002
Identities = 17/40 (42%), Positives = 20/40 (50%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKH 113
C +F C SG+CI + VCD DC D DED H
Sbjct: 222 CGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPH 261
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 8/52 (15%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE-------DPATCSKH-LTCD 117
C ++F C +G+CI+K VCD DC D SDE TC H CD
Sbjct: 3032 CQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCD 3083
Score = 42.7 bits (99), Expect = 0.003
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 6/64 (9%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCSKH-LTCDFESGFCGWEP 127
++C +EF C +G+CI + VCD DC D SDE TC + TC SG C ++
Sbjct: 181 EICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFTC--PSGRCIYQN 238
Query: 128 FLTE 131
++ +
Sbjct: 239 WVCD 242
Score = 42.7 bits (99), Expect = 0.003
Identities = 24/59 (40%), Positives = 28/59 (47%), Gaps = 11/59 (18%)
Query: 900 PERKCTDHEFMCANKH-CIAKDKLCDFVNDCADNSDETTFICRT----------SSGRC 947
P+R C C N + CI + LCD NDC DNSDE C T +SGRC
Sbjct: 2818 PDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRC 2876
Score = 42.4 bits (98), Expect = 0.004
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 16/94 (17%)
Query: 1373 PPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHY 1432
P E P + L S F C++ +C+ ++ LCD DC D SDE C
Sbjct: 1017 PTNEPPTEQCGLFS-------------FPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTL 1063
Query: 1433 TSTTGSCNFETSSGNWTTA---CSLTQDSEDDLD 1463
+T S F G A C D D D
Sbjct: 1064 NNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSD 1097
Score = 42.4 bits (98), Expect = 0.004
Identities = 22/51 (43%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDED------PATC-SKHLTCD 117
CS+ F C G+CI CD R DC D SDE PA+C TCD
Sbjct: 1067 CSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCD 1117
Score = 42.4 bits (98), Expect = 0.004
Identities = 17/46 (36%), Positives = 23/46 (50%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDF 949
C+ F CAN C+ CD+ NDC D SDE + R + +F
Sbjct: 2741 CSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEF 2786
Score = 42.4 bits (98), Expect = 0.004
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
C ++E+ C + +CI + CD+ DC D SDED + C+ TC
Sbjct: 3594 CDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASR-TC 3635
Score = 42.0 bits (97), Expect = 0.005
Identities = 19/46 (41%), Positives = 26/46 (56%)
Query: 60 LWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
L + AC S + C + F C SG CI + CD +DCSD++DE
Sbjct: 14 LALVACLAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE 59
Score = 42.0 bits (97), Expect = 0.005
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDS 133
C FPC +G+C+ +CD DC D SDE + TC + CG + +
Sbjct: 1026 CGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNN-TCSSSAFTCGHGECI--PA 1082
Query: 134 HWKLMK 139
HW+ K
Sbjct: 1083 HWRCDK 1088
Score = 42.0 bits (97), Expect = 0.005
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 684 TLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVC 730
T PP C +EF C+ DG CI +CD DC SDE +CV + C
Sbjct: 1224 TRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTC 1271
Score = 41.6 bits (96), Expect = 0.007
Identities = 16/38 (42%), Positives = 22/38 (57%)
Query: 903 KCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
+C F C+N CI+++ CD NDC D SDE +C
Sbjct: 2699 RCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVC 2736
Score = 41.6 bits (96), Expect = 0.007
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLC 738
P C +EF C +G CIE M+ C+ DC D SDE C + C S C
Sbjct: 3071 PEPTCPPHEFKC-DNGRCIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGC 3122
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 12/91 (13%)
Query: 444 SAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP-- 501
+ +DD R + +C + F C++ CI CD +DCGD +DE NCAP
Sbjct: 3700 NGVDDCRDNSDEQGCEERTCHPVGDFRCKNHH-CIPLRWQCDGQNDCGDNSDEENCAPRE 3758
Query: 502 ---------ELQCNFETGICNWEQDAKDDFD 523
QC IC+ D D+ D
Sbjct: 3759 CTESEFRCVNQQCIPSRWICDHYNDCGDNSD 3789
Score = 41.2 bits (95), Expect = 0.009
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 1119 PTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECG---SSCTFEKGWCG 1169
PT C L C NG+C C+ VD+C DN+DE CG ++C+ CG
Sbjct: 1022 PTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCG 1075
Score = 41.2 bits (95), Expect = 0.009
Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATC--SKHLTCDFESGFC 123
+ C +F C +G+CI + CD DC D SDE C S HL +F C
Sbjct: 3633 RTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSC 3686
Score = 41.2 bits (95), Expect = 0.009
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-------AHYTSTTGSCNFETSSG 1446
C E ++F C +++CI S +CD+ DC D SDE C ++ T+G C
Sbjct: 3759 CTE-SEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCTSGHCVHSELKC 3817
Query: 1447 NWTTACSLTQDSED 1460
+ + C D D
Sbjct: 3818 DGSADCLDASDEAD 3831
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 1388 GEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSC-------- 1439
G ++ C + F C +CI +H CD + DC D SDE +C T SC
Sbjct: 1061 GTLNNTCSS-SAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCP--THAPASCLDTQYTCD 1117
Query: 1440 NFETSSGNWTTACSLTQDSEDDLD 1463
N + S NW C D D D
Sbjct: 1118 NHQCISKNW--VCDTDNDCGDGSD 1139
Score = 40.8 bits (94), Expect = 0.012
Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 22/109 (20%)
Query: 427 PFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDL 486
P H DK + D V D+ NC PA SC LD + CI K +CD
Sbjct: 1081 PAHWRCDKRN----DCVDGSDE---HNCPTHAPA-SC--LDTQYTCDNHQCISKNWVCDT 1130
Query: 487 VDDCGDRTDEVNC------------APELQCNFETGICNWEQDAKDDFD 523
+DCGD +DE NC P +C + +C+ ++D D D
Sbjct: 1131 DNDCGDGSDEKNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSD 1179
Score = 40.8 bits (94), Expect = 0.012
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
T + C ++ C + QCI+K VCD+ DC D SDE C+ TC
Sbjct: 1103 THAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDE--KNCNSTETC 1149
Score = 40.8 bits (94), Expect = 0.012
Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 902 RKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRT--------SSGRCDFEFDL 953
R C+++EF C CI K CD NDC D SDE + +T +GRC + +
Sbjct: 2991 RTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFV 3050
Query: 954 CSWKQEKDEDFD 965
C DED D
Sbjct: 3051 C------DEDND 3056
Score = 40.8 bits (94), Expect = 0.012
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
+ C + F CTSG C+ E CD DC D SDE
Sbjct: 3796 RTCHPEYFQCTSGHCVHSELKCDGSADCLDASDE 3829
Score = 40.4 bits (93), Expect = 0.016
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 1398 TDFLCRDKKCIASHLLCDYKPDCSDRSDE-AHCAHYTSTTGSCNFETSSG 1446
++F C +CI H CD + DC D SDE A C H T + F+ G
Sbjct: 2867 SEFQCASGRCIPQHWYCDQETDCFDASDEPASCGHSERTCLADEFKCDGG 2916
Score = 40.4 bits (93), Expect = 0.016
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
Query: 892 QDCSP-----LLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGR 946
+DCS L P+R C +F C++ +C + LC+ +C D SDE +C +
Sbjct: 3536 KDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLC--ENHH 3593
Query: 947 CDFEFDLCSWKQ 958
CD C+ K+
Sbjct: 3594 CDSNEWQCANKR 3605
Score = 40.4 bits (93), Expect = 0.016
Identities = 16/37 (43%), Positives = 21/37 (56%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
C + DF C++ CI CD + DC D SDE +CA
Sbjct: 3719 CHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCA 3755
Score = 40.0 bits (92), Expect = 0.021
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 12/78 (15%)
Query: 1394 CPEI---TDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSG---- 1446
C EI +F C + +CI +CD+ DC D SDE C + T G F SG
Sbjct: 179 CTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNY--PTCGGYQFTCPSGRCIY 236
Query: 1447 -NWTTACSLTQDSEDDLD 1463
NW C D +D+ D
Sbjct: 237 QNW--VCDGEDDCKDNGD 252
Score = 40.0 bits (92), Expect = 0.021
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C NEF C +G CI + CD DC D SDE +C C
Sbjct: 183 CLHNEFSC-GNGECIPRAYVCDHDNDCQDGSDEHACNYPTC 222
Score = 40.0 bits (92), Expect = 0.021
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 8/89 (8%)
Query: 72 KLCSADEFPC-TSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLT 130
+ C + C S CI + +CD DC D SDE+P C+ H TC C +
Sbjct: 2820 RTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTH-TCSSSEFQCASGRCIP 2878
Query: 131 EDSHWKLMKGLNNGEHHFPAADHTANINH 159
+ HW + F A+D A+ H
Sbjct: 2879 Q--HWY----CDQETDCFDASDEPASCGH 2901
Score = 40.0 bits (92), Expect = 0.021
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE---DPATC-SKHLTCDFESGFC 123
C+ EF C + QCI +CD DC D SDE + TC ++ C SG C
Sbjct: 3759 CTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQC--TSGHC 3810
Score = 39.7 bits (91), Expect = 0.027
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C+ ++ C S+G CI +CD DCPD +DE C C
Sbjct: 108 CSSHQITC-SNGQCIPSEYRCDHVRDCPDGADENDCQYPTC 147
Score = 39.7 bits (91), Expect = 0.027
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1402 CRDKKCIASHLLCDYKPDCSDRSDEAHCAH-----YTSTTGSCNFETSSGNWTTACSLTQ 1456
C + +CI S CD+ DC D +DE C + T G+C + +W C +
Sbjct: 115 CSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDC---R 171
Query: 1457 DSEDDLD 1463
DS D+++
Sbjct: 172 DSSDEIN 178
Score = 39.7 bits (91), Expect = 0.027
Identities = 15/40 (37%), Positives = 21/40 (52%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCG 1169
C NG CY Q C++ +C D++DE C C + CG
Sbjct: 152 CDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCG 191
Score = 39.7 bits (91), Expect = 0.027
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 6/50 (12%)
Query: 688 HNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEAS------CVMEVCS 731
H C+ E+ C G CI + CD DCP + DE + C M +CS
Sbjct: 264 HKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLCS 313
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
Query: 1607 PVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCST 1666
P QP C + Q+ C+ CV LS CDG DC +G+DE PL CS+ C T
Sbjct: 1306 PTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE--SPLC-NGNSCSDFNGGC-T 1361
Query: 1667 DECI 1670
EC+
Sbjct: 1362 HECV 1365
Score = 39.7 bits (91), Expect = 0.027
Identities = 17/35 (48%), Positives = 19/35 (54%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
ER C EF C CI + +CD NDC D SDE
Sbjct: 2903 ERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDE 2937
Score = 39.3 bits (90), Expect = 0.035
Identities = 24/58 (41%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Query: 74 CSADEFPCTSG-QCIAKESVCDSRQDCSDESDE------DPATC-SKHLTCDFESGFC 123
C+A +F C SG +CI + CD DCSD SDE P C S C E G C
Sbjct: 1187 CTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQ-EDGIC 1243
Score = 39.3 bits (90), Expect = 0.035
Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 902 RKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRC 947
+ C F C N +CI + LCD NDC D SDE C T RC
Sbjct: 1269 KTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKD--CPTQPFRC 1312
Score = 39.3 bits (90), Expect = 0.035
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 16/83 (19%)
Query: 1112 EELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN--------------EC 1157
+ELA+ P FC LG +C +G C + CN NC D +DE+ +C
Sbjct: 3543 DELAL-CPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQC 3601
Query: 1158 GSSCTFEKGW-CGWQNSQADNFD 1179
+ + W C N DN D
Sbjct: 3602 ANKRCIPESWQCDTFNDCEDNSD 3624
Score = 39.3 bits (90), Expect = 0.035
Identities = 16/40 (40%), Positives = 21/40 (52%)
Query: 460 AESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
A C+ F C+ CI K +C+ VDDC D +DE C
Sbjct: 3675 AHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGC 3714
Score = 38.9 bits (89), Expect = 0.046
Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 700 DGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
+G C QKCD+K DC D SDE +C E+C
Sbjct: 154 NGACYNTSQKCDWKVDCRDSSDEINCT-EIC 183
Score = 38.9 bits (89), Expect = 0.046
Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 12/75 (16%)
Query: 65 CGQTQSRKLCSADEFPCTSGQ--------CIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
CG K C F C S Q C+ VCD DC + +DE P C+ +
Sbjct: 1296 CGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDESP-LCNGNSCS 1354
Query: 117 DFESGF---CGWEPF 128
DF G C EPF
Sbjct: 1355 DFNGGCTHECVQEPF 1369
Score = 38.9 bits (89), Expect = 0.046
Identities = 21/45 (46%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 682 PVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASC 725
P H C+ +EF C S G CI + CD + DC D SDE ASC
Sbjct: 2856 PTYCTTHTCSSSEFQCAS-GRCIPQHWYCDQETDCFDASDEPASC 2899
Score = 38.9 bits (89), Expect = 0.046
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 11/65 (16%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE---------DPAT--CSKHLTCDFESGF 122
C EF C +G+CI +C+ DC D SDE DP+ C + T S +
Sbjct: 3075 CPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGINECHDPSISGCDHNCTDTLTSFY 3134
Query: 123 CGWEP 127
C P
Sbjct: 3135 CSCRP 3139
Score = 38.5 bits (88), Expect = 0.060
Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 14/82 (17%)
Query: 454 CTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA------------P 501
C P + C+ HF C CI CD DC D DE+ CA
Sbjct: 19 CLAPASGQECDSA-HFRCGSGH-CIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQS 76
Query: 502 ELQCNFETGICNWEQDAKDDFD 523
E QC + +C+ +QD D D
Sbjct: 77 EGQCIPNSWVCDQDQDCDDGSD 98
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 1/43 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVCS 731
C F C+S+G CI CD DC D SDE C CS
Sbjct: 67 CQQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDERQDCSQSTCS 109
Score = 38.5 bits (88), Expect = 0.060
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
P E C GL F C++ R C+ LCD VDDC D +DE C
Sbjct: 1022 PTEQC-GLFSFPCKNGR-CVPNYYLCDGVDDCHDNSDEQLC 1060
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Query: 1106 LHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
L+ S + VP CP Y C NG C C+ ++CGD +DE +C
Sbjct: 1257 LYGSDEHNACVPKT---CPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDC 1305
Score = 38.5 bits (88), Expect = 0.060
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 689 NCTDNEFICRS----DGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVCSFEKRSLCKWYQP 743
NC+D+EF+C + D CI + CD DC D DE +C CS E C +
Sbjct: 2947 NCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRTCS-ENEFTCGYGLC 3005
Query: 744 IP 745
IP
Sbjct: 3006 IP 3007
Score = 38.5 bits (88), Expect = 0.060
Identities = 27/113 (23%), Positives = 41/113 (36%), Gaps = 13/113 (11%)
Query: 893 DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC-----------R 941
DC C F C N CI CD +DC D SDE +C R
Sbjct: 3831 DCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFR 3890
Query: 942 TSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYI 994
+ RC + ++C+ + + D + P +P ++ +GH I
Sbjct: 3891 CDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPT--PKPCTEYEYKCGNGHCI 3941
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
P CT+ E+ C +GHCI CD DC D SDE C
Sbjct: 3925 PKPCTEYEYKC-GNGHCIPHDNVCDDADDCGDWSDELGC 3962
Score = 38.1 bits (87), Expect = 0.079
Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTG--SCNFETSSGNWTTACSLTQD 1457
F C CI + CD DCSD +DE CA T G C E + C QD
Sbjct: 33 FRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSEGQCIPNSWVCDQDQD 92
Query: 1458 SEDDLD 1463
+D D
Sbjct: 93 CDDGSD 98
Score = 38.1 bits (87), Expect = 0.079
Identities = 16/45 (35%), Positives = 24/45 (53%)
Query: 1696 CSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSDTWTLLG 1740
CS+ +CA++ CIP +CDG DC D + + C + LG
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLG 3556
Score = 38.1 bits (87), Expect = 0.079
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVC 730
C+ +F+C ++ CI KCD + DC D SDE A C C
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFC 3553
Score = 38.1 bits (87), Expect = 0.079
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEA--HCAHYT-STTGSCNFETSSGNWTT 1450
C F C + +CI SH +C+ DC D +DE HC T ++ +G+
Sbjct: 3883 CNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIP 3942
Query: 1451 ACSLTQDSEDDLDWA 1465
++ D++D DW+
Sbjct: 3943 HDNVCDDADDCGDWS 3957
Score = 37.7 bits (86), Expect = 0.10
Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C F C S GHCI +CD DC D +DE C + C
Sbjct: 28 CDSAHFRCGS-GHCIPADWRCDGTKDCSDDADEIGCAVVTC 67
Score = 37.7 bits (86), Expect = 0.10
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 684 TLPPHNCTDNEFICRSDGH-CIEKMQKCDFKYDCPDKSDEASC 725
T P +C D ++ C D H CI K CD DC D SDE +C
Sbjct: 1103 THAPASCLDTQYTC--DNHQCISKNWVCDTDNDCGDGSDEKNC 1143
Score = 37.7 bits (86), Expect = 0.10
Identities = 37/118 (31%), Positives = 44/118 (37%), Gaps = 24/118 (20%)
Query: 418 TIQLGRLSQPFHLSLDK--VSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTR 475
T Q + + P H +D V G D V D++ C L A F C
Sbjct: 1148 TCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEV---GCVLNCTASQ------FKCASGD 1198
Query: 476 ACIEKLRLCDLVDDCGDRTDEVNC---------APELQCNFETGIC---NWEQDAKDD 521
CI CD V DC D +DE C + E QC E GIC WE D D
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQ-EDGICIPNFWECDGHPD 1255
Score = 37.7 bits (86), Expect = 0.10
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
K C + F C +G CI + +CD DC D SDE
Sbjct: 1269 KTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDE 1302
Score = 37.7 bits (86), Expect = 0.10
Identities = 17/43 (39%), Positives = 21/43 (48%)
Query: 893 DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
D +P C+ EF CA+ CI + CD DC D SDE
Sbjct: 2853 DENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDE 2895
Score = 37.7 bits (86), Expect = 0.10
Identities = 19/49 (38%), Positives = 23/49 (46%)
Query: 1108 DSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENE 1156
D EEL + L C N +C + CN VD+CGD TDE E
Sbjct: 3869 DGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETE 3917
Score = 37.4 bits (85), Expect = 0.13
Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSD--EASCVMEVCS 731
C + F C S+G CI + KCD DC D SD E+ C + CS
Sbjct: 2700 CGASSFTC-SNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCS 2742
Score = 37.4 bits (85), Expect = 0.13
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 1398 TDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
T F C + +C+ CDY DC D SDEA C
Sbjct: 2744 TAFTCANGRCVQYSYRCDYYNDCGDGSDEAGC 2775
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 1124 PLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECG-SSCTFEKGWCGWQNSQADNFDWV 1181
P+G C N C L C+ ++CGDN+DE C CT + C N Q W+
Sbjct: 3721 PVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPRECTESEFRC--VNQQCIPSRWI 3777
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 10/85 (11%)
Query: 66 GQTQSRKLCSADEFPCTSGQ-CIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
G T +CS+ +F C + + CI CD ++DCSD SDE A C + FC
Sbjct: 3504 GSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDE-LALCPQR--------FCR 3554
Query: 125 WEPFLTEDSHWKLMKGLNNGEHHFP 149
F D + + L N + P
Sbjct: 3555 LGQFQCSDGNCTSPQTLCNAHQNCP 3579
Score = 36.6 bits (83), Expect = 0.23
Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 11/58 (18%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNC-----------APELQCNFETGICNWEQDAKDDFD 523
CI + +CD +DC D +DE C P +C ++ +C+ E D KD+ D
Sbjct: 195 CIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFTCPSGRCIYQNWVCDGEDDCKDNGD 252
Score = 36.6 bits (83), Expect = 0.23
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI--CRTSSGRC 947
C +F C N CI +CD DC D SDE + C S +C
Sbjct: 1149 CQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKC 1194
Score = 36.6 bits (83), Expect = 0.23
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDR--SDEAHCAHYTSTTG 1437
C T+F+C +++CI +C+ +C D SDE +C T +G
Sbjct: 2780 CNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQSG 2825
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/78 (30%), Positives = 28/78 (35%), Gaps = 3/78 (3%)
Query: 679 TSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE--ASCVMEVCSFEKRS 736
TS P C C + CI ++ CD DC D SDE C CS
Sbjct: 2811 TSDEKNCPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCS-SSEF 2869
Query: 737 LCKWYQPIPVHLLQDSNT 754
C + IP H D T
Sbjct: 2870 QCASGRCIPQHWYCDQET 2887
Score = 36.2 bits (82), Expect = 0.30
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 11/61 (18%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC-----------GSSCTFEKGWCGWQNSQADNF 1178
C NG+C E C+ V +C D DEN+C +C C W+ D+
Sbjct: 115 CSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSS 174
Query: 1179 D 1179
D
Sbjct: 175 D 175
Score = 36.2 bits (82), Expect = 0.30
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 1398 TDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
T + C + +CI+ + +CD DC D SDE +C
Sbjct: 1112 TQYTCDNHQCISKNWVCDTDNDCGDGSDEKNC 1143
Score = 36.2 bits (82), Expect = 0.30
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 70 SRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
S + C +F C + +CI VCD +DC D SDE
Sbjct: 1145 STETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDE 1180
Score = 36.2 bits (82), Expect = 0.30
Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Query: 904 CTDHEFMCAN-KHCIAKDKLCDFVNDCADNSDE 935
CT +F CA+ CI CD V DC+DNSDE
Sbjct: 1187 CTASQFKCASGDKCIGVTNRCDGVFDCSDNSDE 1219
Score = 36.2 bits (82), Expect = 0.30
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 1119 PTGFCPLGYRECHNGK-CYRLEQSCNFVDNCGDNTDEN 1155
P C GY +CHN C C+ ++CGDN+DEN
Sbjct: 2818 PDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDEN 2855
Score = 35.8 bits (81), Expect = 0.39
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
P C + F C +G+CI + CD DC D SDE C
Sbjct: 1268 PKTCPSSYFHC-DNGNCIHRAWLCDRDNDCGDMSDEKDC 1305
Score = 35.8 bits (81), Expect = 0.39
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
CS F C +G+C+ CD DC D SDE
Sbjct: 2741 CSPTAFTCANGRCVQYSYRCDYYNDCGDGSDE 2772
Score = 35.8 bits (81), Expect = 0.39
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Query: 908 EFMCANKHCIAKDKLCDFVNDCADN--SDETTFICRT 942
EFMC N+ CI ++ +C+ V++C DN SDE RT
Sbjct: 2785 EFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCPDRT 2821
Score = 35.8 bits (81), Expect = 0.39
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 7/60 (11%)
Query: 902 RKCTDHEFMCAN-----KHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE--FDLC 954
+ C+D EF+C N + CI + +CD DC D DE R + +F + LC
Sbjct: 2946 QNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGYGLC 3005
Score = 35.8 bits (81), Expect = 0.39
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Query: 1388 GEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDE-AHCAHYTS-TTGSCNFETSS 1445
G + + C + F C++ +CI+ +CD DC D SDE H H T F+ +
Sbjct: 3026 GCLYQTCQQ-NQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDN 3084
Query: 1446 GNWTTACSLTQDSEDDLD 1463
G L +D LD
Sbjct: 3085 GRCIEMMKLCNHLDDCLD 3102
Score = 35.8 bits (81), Expect = 0.39
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C N+F C++ G CI K CD DC D SDE +M +C
Sbjct: 3032 CQQNQFTCQN-GRCISKTFVCDEDNDCGDGSDE---LMHLC 3068
Score = 35.8 bits (81), Expect = 0.39
Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 14/74 (18%)
Query: 904 CTDHEFMCANKH-CIAKDKLCDFVNDCADNSDETTF----ICR-----TSSGRCDFEFDL 953
C+ +F+CAN CI CD DC+D SDE CR S G C L
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTL 3571
Query: 954 CSWKQE----KDED 963
C+ Q DED
Sbjct: 3572 CNAHQNCPDGSDED 3585
Score = 35.8 bits (81), Expect = 0.39
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1391 SELCPEITDFLCRDK-KCIASHLLCDYKPDCSDRSDEAHCAHYT 1433
+ LC T+F C+ +CI +C+ DC D SDE C T
Sbjct: 3675 AHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERT 3718
Score = 35.4 bits (80), Expect = 0.51
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 463 CEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEV--NC-------APELQCNFETGIC- 512
C + F C + R CI +C+ VDDCGD TDE +C E + G C
Sbjct: 3883 CNSPNRFRCDNNR-CIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCI 3941
Query: 513 ---NWEQDAKDDFDWTRSQG 529
N DA D DW+ G
Sbjct: 3942 PHDNVCDDADDCGDWSDELG 3961
Score = 35.4 bits (80), Expect = 0.51
Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 15/104 (14%)
Query: 75 SADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL--TCDFESGFCGWEPFLTED 132
S + F C + +CI VC+ DC D +DE C K C CG + D
Sbjct: 3885 SPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHD 3944
Query: 133 S---------HWKLMKGLNNGEHHFPAAD----HTANINHGSFI 163
+ W G N G+ A + + +N G FI
Sbjct: 3945 NVCDDADDCGDWSDELGCNKGKERTCAENICEQNCTQLNEGGFI 3988
Score = 35.0 bits (79), Expect = 0.67
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 688 HNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
+ C+ + F C G CI +CD + DC D SDE +C
Sbjct: 1065 NTCSSSAFTC-GHGECIPAHWRCDKRNDCVDGSDEHNC 1101
Score = 35.0 bits (79), Expect = 0.67
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 1391 SELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA-HYTSTTGSCNFETSSGNWT 1449
+E C + + F C + +CI +CD DC D SDE C + T++ C T
Sbjct: 1146 TETC-QPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKCIGVT 1204
Query: 1450 TACSLTQDSEDDLDWA 1465
C D D+ D A
Sbjct: 1205 NRCDGVFDCSDNSDEA 1220
Score = 35.0 bits (79), Expect = 0.67
Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 6/56 (10%)
Query: 68 TQSRKLCSADEFPCTS-GQCIAKESVCDSRQDCSDESDED----PATC-SKHLTCD 117
T+ +C +DEF C G CI CD DC SDE P TC S + CD
Sbjct: 1224 TRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTCPSSYFHCD 1279
Score = 35.0 bits (79), Expect = 0.67
Identities = 11/28 (39%), Positives = 18/28 (64%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C NG+C + C++ ++CGD +DE C
Sbjct: 2748 CANGRCVQYSYRCDYYNDCGDGSDEAGC 2775
Score = 35.0 bits (79), Expect = 0.67
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 17/83 (20%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-------- 503
+NCT +E+ F C + CI K+ CD +DCGD +DE C +
Sbjct: 2986 QNCTRRTCSEN-----EFTCGYG-LCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQFTC 3039
Query: 504 ---QCNFETGICNWEQDAKDDFD 523
+C +T +C+ + D D D
Sbjct: 3040 QNGRCISKTFVCDEDNDCGDGSD 3062
Score = 35.0 bits (79), Expect = 0.67
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 6/47 (12%)
Query: 1389 EISELC--PEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
E+ LC PE T +F C + +CI LC++ DC D SDE C
Sbjct: 3063 ELMHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGC 3109
Score = 35.0 bits (79), Expect = 0.67
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
Query: 1101 ENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
++C D +E P P Y+ C NG C + C+ D+CGD +DE C
Sbjct: 3907 DDCGDGTDETEEHCRKPTPKPCTEYEYK-CGNGHCIPHDNVCDDADDCGDWSDELGC 3962
Score = 34.7 bits (78), Expect = 0.87
Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 1379 NRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGS 1438
NR+ ++ GE + F C + +CI+ CD DC D SDE T
Sbjct: 2688 NRKHCIVDNGERCGA----SSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSP 2743
Query: 1439 CNFETSSG---NWTTACSLTQDSEDDLDWA 1465
F ++G ++ C D D D A
Sbjct: 2744 TAFTCANGRCVQYSYRCDYYNDCGDGSDEA 2773
Score = 34.7 bits (78), Expect = 0.87
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 3/46 (6%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDN--TDENECGSSCTFEKGWCGWQNS 1173
C+N +C E CN VDNC DN +DE C T + G+ NS
Sbjct: 2788 CNNRRCIPREFICNGVDNCHDNNTSDEKNCPDR-TCQSGYTKCHNS 2832
Score = 34.7 bits (78), Expect = 0.87
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 7/57 (12%)
Query: 74 CSADEFPCTSGQ-----CIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGW 125
CS EF C + + CI + VCD DC+D DE+ C++ TC CG+
Sbjct: 2948 CSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDEN-QNCTRR-TCSENEFTCGY 3002
Score = 34.3 bits (77), Expect = 1.1
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C+ F C + CI CD NDC D SDE
Sbjct: 1067 CSSSAFTCGHGECIPAHWRCDKRNDCVDGSDE 1098
Score = 34.3 bits (77), Expect = 1.1
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDE 496
+NC P +C+ + C ++ CI ++ LCD +DCGD +DE
Sbjct: 2815 KNC----PDRTCQS-GYTKCHNSNICIPRVYLCDGDNDCGDNSDE 2854
Score = 34.3 bits (77), Expect = 1.1
Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 1/31 (3%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
F C + R CIE ++LC+ +DDC D +DE C
Sbjct: 3080 FKCDNGR-CIEMMKLCNHLDDCLDNSDEKGC 3109
Score = 34.3 bits (77), Expect = 1.1
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Query: 434 KVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDR 493
+V G+ D D+ E+C P P E + C + CI +CD DDCGD
Sbjct: 3901 EVCNGVDDCGDGTDETE-EHCRKPTPKPCTEY--EYKCGNGH-CIPHDNVCDDADDCGDW 3956
Query: 494 TDEVNCAPELQCNFETGIC 512
+DE+ C + IC
Sbjct: 3957 SDELGCNKGKERTCAENIC 3975
Score = 33.9 bits (76), Expect = 1.5
Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 74 CSAD-EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGF 122
C+A EF C + +CI +E +C+ +C D + D C TC +SG+
Sbjct: 2780 CNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCPDR-TC--QSGY 2826
Score = 33.9 bits (76), Expect = 1.5
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDE--NECGSS 1160
C G C NG+C C+ ++CGD++DE EC SS
Sbjct: 3635 CRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSS 3674
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 18/72 (25%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTD-----------------EVNCAPELQCNFETGI 511
F C + R CI + CD+ +DCGD +D E +C +C + +
Sbjct: 3640 FRCANGR-CIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAV 3698
Query: 512 CNWEQDAKDDFD 523
CN D +D+ D
Sbjct: 3699 CNGVDDCRDNSD 3710
Score = 33.9 bits (76), Expect = 1.5
Identities = 15/37 (40%), Positives = 17/37 (45%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATC 110
C A F C + CI CD DC D SDE+ C
Sbjct: 3842 CQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLC 3878
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 6/66 (9%)
Query: 1120 TGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC------GSSCTFEKGWCGWQNS 1173
T C C NG+C C+ ++C D +DE+ C G T G C +QN
Sbjct: 180 TEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFTCPSGRCIYQNW 239
Query: 1174 QADNFD 1179
D D
Sbjct: 240 VCDGED 245
Score = 33.5 bits (75), Expect = 1.9
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 74 CSADEFPCT-SGQCIAKESVCDSRQDCSDESDEDPATCSKH 113
CS E+ C SG+CI+ VCD DC DE+ + K+
Sbjct: 266 CSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Score = 33.5 bits (75), Expect = 1.9
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 1390 ISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
+ + CP + F C + CI LCD DC D SDE C
Sbjct: 1267 VPKTCPS-SYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDC 1305
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 13/84 (15%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNC-------APELQCNF-----ETGICNWEQ 516
F C + R C++ CD +DCGD +DE C E CN ICN
Sbjct: 2746 FTCANGR-CVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVD 2804
Query: 517 DAKDDFDWTRSQGPTPTLNTGPMK 540
+ D+ P T +G K
Sbjct: 2805 NCHDNNTSDEKNCPDRTCQSGYTK 2828
Score = 33.1 bits (74), Expect = 2.5
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 20/76 (26%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDE--------VNCA-----------PELQCNF 507
D F C R CI +CD +DCGD +DE NC+ P+ +C
Sbjct: 2909 DEFKCDGGR-CIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIP 2967
Query: 508 ETGICNWEQDAKDDFD 523
++ +C+ + D D +D
Sbjct: 2968 QSWVCDGDVDCTDGYD 2983
Score = 33.1 bits (74), Expect = 2.5
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 11/80 (13%)
Query: 1393 LCPE----ITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA----HYTSTTGSC-NFET 1443
LCP+ + F C D C + LC+ +C D SDE H S C N
Sbjct: 3547 LCPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRC 3606
Query: 1444 SSGNWTTACSLTQDSEDDLD 1463
+W C D ED+ D
Sbjct: 3607 IPESW--QCDTFNDCEDNSD 3624
Score = 33.1 bits (74), Expect = 2.5
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 7/54 (12%)
Query: 70 SRKLC-SADEFPC-TSGQCIAKESVCDSRQDCSDESDE---DPATCSKHLTCDF 118
S LC + EF C T+ +CI K +VC+ DC D SDE + TC H DF
Sbjct: 3674 SAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTC--HPVGDF 3725
Score = 33.1 bits (74), Expect = 2.5
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDED---PATCSK 112
+F C + CI CD + DC D SDE+ P C++
Sbjct: 3724 DFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPRECTE 3761
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/35 (37%), Positives = 17/35 (48%)
Query: 1395 PEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
P C + C + CD+K DC D SDE +C
Sbjct: 145 PTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINC 179
Score = 32.7 bits (73), Expect = 3.3
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 1/54 (1%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQP 743
C +F C S G CI + CD + DC D DE C K S +W P
Sbjct: 222 CGGYQFTCPS-GRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCP 274
Score = 32.7 bits (73), Expect = 3.3
Identities = 17/40 (42%), Positives = 19/40 (47%)
Query: 1407 CIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSG 1446
CI LCD DC D SDE T T S F+ +SG
Sbjct: 2835 CIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASG 2874
Score = 32.7 bits (73), Expect = 3.3
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 16/72 (22%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEV---------NCAP-ELQCNFETGI----- 511
+ F C++ R CI K +CD +DCGD +DE+ C P E +C+ I
Sbjct: 3035 NQFTCQNGR-CISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEMMKL 3093
Query: 512 CNWEQDAKDDFD 523
CN D D+ D
Sbjct: 3094 CNHLDDCLDNSD 3105
Score = 32.7 bits (73), Expect = 3.3
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 3/50 (6%)
Query: 1108 DSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
D+ EE P C C N +C C+ ++CGDN+DE +C
Sbjct: 3747 DNSDEENCAPRE---CTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDC 3793
Score = 32.3 bits (72), Expect = 4.3
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
F C +CI + +CD + DC D DE C
Sbjct: 227 FTCPSGRCIYQNWVCDGEDDCKDNGDEDGC 256
Score = 32.3 bits (72), Expect = 4.3
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 4/64 (6%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC--VMEVCSFEKRSLCKWYQP 743
P C F C++ G C+ CD DC D SDE C + CS C +
Sbjct: 1022 PTEQCGLFSFPCKN-GRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCS-SSAFTCGHGEC 1079
Query: 744 IPVH 747
IP H
Sbjct: 1080 IPAH 1083
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 1107 HDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC----GSSCT 1162
HD+ E+L L C C +G+C C+ ++C D +DE+ C +SC
Sbjct: 1052 HDNSDEQLCGTL-NNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPASCL 1110
Query: 1163 FEKGWCGWQNSQADNFDWV 1181
+ C N Q + +WV
Sbjct: 1111 DTQYTC--DNHQCISKNWV 1127
Score = 32.3 bits (72), Expect = 4.3
Identities = 12/23 (52%), Positives = 16/23 (69%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNC 499
CI + LCD +DCGD +DE +C
Sbjct: 1283 CIHRAWLCDRDNDCGDMSDEKDC 1305
Score = 32.3 bits (72), Expect = 4.3
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDE 1426
+F C +CI S +CD DC D SDE
Sbjct: 2910 EFKCDGGRCIPSEWICDGDNDCGDMSDE 2937
Score = 32.3 bits (72), Expect = 4.3
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 6/48 (12%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
ENC P E E F C + + CI +CD +DCGD +DE +C
Sbjct: 3752 ENCA---PRECTES--EFRCVNQQ-CIPSRWICDHYNDCGDNSDERDC 3793
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 15/79 (18%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTD-EVNCAPELQCN-------------FETGICNW 514
F C++ CI CD DDCGD +D E++ ++ CN + +CN
Sbjct: 3847 FECKN-HVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNG 3905
Query: 515 EQDAKDDFDWTRSQGPTPT 533
D D D T PT
Sbjct: 3906 VDDCGDGTDETEEHCRKPT 3924
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 476 ACIEKLRLCDLVDDCGDRTDEVNCAPE-LQCNFETG---------ICNWEQDAKDDFDWT 525
AC + CD DC D +DE+NC L F G +C+ + D +D D
Sbjct: 156 ACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEH 215
Query: 526 RSQGPT 531
PT
Sbjct: 216 ACNYPT 221
Score = 32.0 bits (71), Expect = 5.6
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVM 727
C ++F C + CI+ CD DC D SDE CV+
Sbjct: 1149 CQPSQFNCPNH-RCIDLSFVCDGDKDCVDGSDEVGCVL 1185
Score = 32.0 bits (71), Expect = 5.6
Identities = 12/27 (44%), Positives = 17/27 (62%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENE 1156
C NG+C E C+ ++CGD +DE E
Sbjct: 2707 CSNGRCISEEWKCDNDNDCGDGSDEME 2733
Score = 31.6 bits (70), Expect = 7.4
Identities = 14/52 (26%), Positives = 24/52 (46%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWV 1181
C N +C C+ ++CGD +DE C S+ T + N + + +V
Sbjct: 1116 CDNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPNHRCIDLSFV 1167
Score = 31.6 bits (70), Expect = 7.4
Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 1/40 (2%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYT 1433
C E +F C CI CD DC D SDE C + T
Sbjct: 2993 CSE-NEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQT 3031
Score = 31.2 bits (69), Expect = 9.6
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNC----APELQCN----FETG-ICNWEQDAKDDFD 523
CI CD V DC D DE +C +L C+ + T C+W+ D +D D
Sbjct: 120 CIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSD 175
Score = 31.2 bits (69), Expect = 9.6
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1406 KCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCN 1440
KCI CD DCSD SDEA C T G C+
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCP--TRPPGMCH 1231
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 99.8 bits (247), Expect = 2e-20
Identities = 56/132 (42%), Positives = 64/132 (48%), Gaps = 9/132 (6%)
Query: 1605 PVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPC 1664
P V+P PC + +C C+P CDG EDC DGSDE+DC P PP C EFPC
Sbjct: 277 PGSVRPLPCGPQEAAC-RNGHCIPRDYLCDGQEDCEDGSDELDC--GPPPP-CEPNEFPC 332
Query: 1665 STDECIPSLLLCDGVPDCHFNEDELICSNKS----CSNGALVCASSNSCIPAHQRCDGFA 1720
C L CDG DC DE C K C C S+N CIPA CD +
Sbjct: 333 GNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEES 392
Query: 1721 DCMDFQLDESSC 1732
DC D + DE C
Sbjct: 393 DCPD-RSDEFGC 403
Score = 73.2 bits (178), Expect = 2e-12
Identities = 53/172 (30%), Positives = 66/172 (38%), Gaps = 45/172 (26%)
Query: 1604 GPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCP-----LSPT----- 1653
G VP P C +F+C +CV L +CD DC D SDE++C +SPT
Sbjct: 190 GTVPQFPRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLV 249
Query: 1654 ----------------PPL----------------CSNMEFPCSTDECIPSLLLCDGVPD 1681
PP+ C E C CIP LCDG D
Sbjct: 250 ETTSLPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQED 309
Query: 1682 CHFNEDELICS-NKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
C DEL C C C + + C RCDG DC D + DE++C
Sbjct: 310 CEDGSDELDCGPPPPCEPNEFPCGNGH-CALKLWRCDGDFDCED-RTDEANC 359
Score = 49.7 bits (117), Expect = 3e-05
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
PP C NEF C +GHC K+ +CD +DC D++DEA+C
Sbjct: 321 PPPPCEPNEFPC-GNGHCALKLWRCDGDFDCEDRTDEANC 359
Score = 45.4 bits (106), Expect = 5e-04
Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 1592 DDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDC--P 1649
+D + C T P V C QF C+ T C+P S CD DC D SDE C P
Sbjct: 351 EDRTDEANCPTKRPEEV----CGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPP 406
Query: 1650 LSPTPP 1655
TPP
Sbjct: 407 QVVTPP 412
Score = 43.1 bits (100), Expect = 0.002
Identities = 17/39 (43%), Positives = 22/39 (56%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
P CT+ EF C S C+ +CD + DC D SDE +C
Sbjct: 196 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNC 234
Score = 43.1 bits (100), Expect = 0.002
Identities = 19/49 (38%), Positives = 24/49 (48%)
Query: 678 ETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
E + P P C +F C S CI CD + DCPD+SDE C+
Sbjct: 356 EANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCM 404
Score = 42.4 bits (98), Expect = 0.004
Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 677 PETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
P+ +P ++ P C E CR+ GHCI + CD + DC D SDE C
Sbjct: 272 PQPLLPGSVRPLPCGPQEAACRN-GHCIPRDYLCDGQEDCEDGSDELDC 319
Score = 41.2 bits (95), Expect = 0.009
Identities = 17/32 (53%), Positives = 18/32 (56%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C E C N HCI +D LCD DC D SDE
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE 316
Score = 40.8 bits (94), Expect = 0.012
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
C E C +G CI ++ +CD ++DC D SDE C C+ CG
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE--LDCGPPPPCEPNEFPCG 333
Score = 40.4 bits (93), Expect = 0.016
Identities = 21/49 (42%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 453 NCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP 501
NC P E C G F C T CI CD DC DR+DE C P
Sbjct: 358 NCPTKRPEEVC-GPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMP 405
Score = 38.9 bits (89), Expect = 0.046
Identities = 38/142 (26%), Positives = 47/142 (33%), Gaps = 22/142 (15%)
Query: 1323 APNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLKGPPQE-KPNRR 1381
AP P+L GS G Q+ G + +C G L GPP +PN
Sbjct: 271 APQPLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELDCGPPPPCEPN-- 328
Query: 1382 SALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC--AHYTSTTGSC 1439
+F C + C CD DC DR+DEA+C G
Sbjct: 329 -----------------EFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPT 371
Query: 1440 NFETSSGNWTTACSLTQDSEDD 1461
F S N S D E D
Sbjct: 372 QFRCVSTNMCIPASFHCDEESD 393
Score = 38.1 bits (87), Expect = 0.079
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C +EFPC +G C K CD DC D +DE
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDE 356
Score = 37.7 bits (86), Expect = 0.10
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 1386 SVGEISELCPEITDFLCRD-KKCIASHLLCDYKPDCSDRSDEAHCAHYT---STTGSCNF 1441
+V + C E +F C +C+A CD +PDC D SDE +C S T S
Sbjct: 191 TVPQFPRACTE-AEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLV 249
Query: 1442 ETSS 1445
ET+S
Sbjct: 250 ETTS 253
Score = 37.4 bits (85), Expect = 0.13
Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 69 QSRKLCSADEFPCTS-GQCIAKESVCDSRQDCSDESDE 105
Q + C+ EF C S +C+A E CD R DC D SDE
Sbjct: 194 QFPRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE 231
Score = 36.6 bits (83), Expect = 0.23
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 1363 PRGRSALLKGPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSD 1422
PR + +++ PP + L G + L + CR+ CI LCD + DC D
Sbjct: 256 PRPETTIMRQPPVTHAPQP---LLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDCED 312
Query: 1423 RSDEAHC 1429
SDE C
Sbjct: 313 GSDELDC 319
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 7/55 (12%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTF-------ICRTSSGRC 947
P C +EF C N HC K CD DC D +DE +C + RC
Sbjct: 321 PPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRC 375
Score = 35.4 bits (80), Expect = 0.51
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 882 GDVAVDDISFQDCSPLLSPERKCTDHEFMCANKH-CIAKDKLCDFVNDCADNSDE 935
GD +D + + P PE C +F C + + CI CD +DC D SDE
Sbjct: 346 GDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDE 400
Score = 34.3 bits (77), Expect = 1.1
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 65 CGQTQSRKLCSADEFPCTS-GQCIAKESVCDSRQDCSDESDE 105
C + ++C +F C S CI CD DC D SDE
Sbjct: 359 CPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDE 400
Score = 33.9 bits (76), Expect = 1.5
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 902 RKCTDHEFMCAN-KHCIAKDKLCDFVNDCADNSDE 935
R CT+ EF C + C+A + CD DC D SDE
Sbjct: 197 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE 231
Score = 33.9 bits (76), Expect = 1.5
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 457 PLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQC 505
PLP E CR+ CI + LCD +DC D +DE++C P C
Sbjct: 282 PLPCGPQEAA----CRNGH-CIPRDYLCDGQEDCEDGSDELDCGPPPPC 325
Score = 32.7 bits (73), Expect = 3.3
Identities = 24/56 (42%), Positives = 26/56 (46%), Gaps = 8/56 (14%)
Query: 453 NCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC---APELQC 505
+C P P E E F C + C KL CD DC DRTDE NC PE C
Sbjct: 318 DCGPPPPCEPNE----FPCGNGH-CALKLWRCDGDFDCEDRTDEANCPTKRPEEVC 368
Score = 32.3 bits (72), Expect = 4.3
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 1124 PLGYRE--CHNGKCYRLEQSCNFVDNCGDNTDENECG 1158
P G +E C NG C + C+ ++C D +DE +CG
Sbjct: 284 PCGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELDCG 320
Score = 31.6 bits (70), Expect = 7.4
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 1398 TDFLC-RDKKCIASHLLCDYKPDCSDRSDEAHC 1429
T F C CI + CD + DC DRSDE C
Sbjct: 371 TQFRCVSTNMCIPASFHCDEESDCPDRSDEFGC 403
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 99.4 bits (246), Expect = 3e-20
Identities = 65/189 (34%), Positives = 100/189 (52%), Gaps = 12/189 (6%)
Query: 494 TDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLY 553
+ E+N ++ CNFE G C W QD DD +W R QG T + TGP D+T G A G Y+
Sbjct: 336 SSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYIS 395
Query: 554 IESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSD-SRGQLL 612
+ P Q+ LLS L+ T C F+YHM+G+ +++L+I I +D + + +
Sbjct: 396 TPTG-PGGRQERVGLLSLPLDPTLEPAC-LSFWYHMYGENVHKLSI--NISNDQNMEKTV 451
Query: 613 WQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLS----FMDCTLYPGN 668
+Q GN G+ W + ++ F++ A + DIA+DD+S + +LYP
Sbjct: 452 FQKEGNYGDNWNYGQVTLNETVKFKVAFNA-FKNKILSDIALDDISLTYGICNGSLYPE- 509
Query: 669 LPADLPTPP 677
P +PTPP
Sbjct: 510 -PTLVPTPP 517
Score = 72.0 bits (175), Expect = 5e-12
Identities = 48/154 (31%), Positives = 71/154 (46%), Gaps = 2/154 (1%)
Query: 947 CDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMR 1006
C+FE C W Q+ ++D +W S + T P DHT GN+SG YI + + R
Sbjct: 347 CNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQER 406
Query: 1007 AARISSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRRE 1066
+S P+ C + F YHMYG + L++ + N K + G+ W
Sbjct: 407 VGLLSLPLDPTLEPAC-LSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYG 465
Query: 1067 ELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLT 1100
+++L F++ F K DIALDDI LT
Sbjct: 466 QVTLNETVKFKVAFNAFKNK-ILSDIALDDISLT 498
Score = 60.8 bits (146), Expect = 1e-08
Identities = 51/176 (28%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY 789
C+FE C W Q L D N + G+ S G P+ DHT G+Y+
Sbjct: 347 CNFED-GFCFWVQD-----LNDDNEWERIQGSTFSPFTG-----PNFDHTFGNASGFYIS 395
Query: 790 ADSSNGKFGDTADILT-PIISLTGPKCTLVFWTHMNGATVGSLQVLIKKD-NVTSKLWAQ 847
+ G + +L+ P+ P C L FW HM G V L + I D N+ ++ +
Sbjct: 396 TPTGPGGRQERVGLLSLPLDPTLEPAC-LSFWYHMYGENVHKLSINISNDQNMEKTVFQK 454
Query: 848 TGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDIS--FQDCSPLLSPE 901
G G W +V L ++ F A + + D+A+DDIS + C+ L PE
Sbjct: 455 EGNYGDNWNYGQVTLNETVKFKVAFNAFKN-KILSDIALDDISLTYGICNGSLYPE 509
Score = 58.9 bits (141), Expect = 4e-08
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 17/165 (10%)
Query: 114 LTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGV 173
+ C+FE GFC W L +D+ W+ ++G P DHT + S Y+ PG
Sbjct: 345 INCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHT--FGNASGFYISTPTGPGG 402
Query: 174 AKLGSPVLTKLLTAS-TPCQVQFWYHLSQHSNLSVFTRTSLDGNL-----QKQGKIIRFS 227
+ +L+ L + P + FWYH+ + + S D N+ QK+G
Sbjct: 403 RQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNY---- 458
Query: 228 ESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVS 272
W++ ++ L T+ F++ A + +ALDDIS++
Sbjct: 459 GDNWNYGQVTL-----NETVKFKVAFNAFKNKILSDIALDDISLT 498
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/175 (29%), Positives = 70/175 (40%), Gaps = 17/175 (9%)
Query: 1438 SCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIP----DSDHTPGSGQHFLYVN 1493
+CNFE W QD DD +W RI P + DHT G+ F Y++
Sbjct: 346 NCNFEDGFCFWV------QDLNDDNEW---ERIQGSTFSPFTGPNFDHTFGNASGF-YIS 395
Query: 1494 SSGSKEGSVARI-TTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSV 1552
+ G R+ S +L + FW++M ++ L + + + V+
Sbjct: 396 TPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYG-ENVHKLSINISNDQNMEKTVFQK 454
Query: 1553 IGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVP 1607
GN W YG V L+ FKVAF A IALDDIS T G P
Sbjct: 455 EGNYGDNWNYGQVTLNETVKFKVAFNA-FKNKILSDIALDDISLTYGICNGSLYP 508
Score = 52.8 bits (125), Expect = 3e-06
Identities = 23/39 (58%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDC 1648
P PC+AD F C +CVPL CDGH C DGSDE DC
Sbjct: 640 PEPCKADHFQC-KNGECVPLVNLCDGHLHCEDGSDEADC 677
Score = 41.6 bits (96), Expect = 0.007
Identities = 38/157 (24%), Positives = 65/157 (41%), Gaps = 9/157 (5%)
Query: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
C+FE C W + ++ D+ +W R S S P DH+ + G ++
Sbjct: 347 CNFEDGFCFWVQDLNDDN-EWERIQGSTFSP---FTGPNFDHTFGNASGFYISTPTGPGG 402
Query: 354 LWQ-VAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGK 412
+ V L P P C LSFW++ YG +V + + + + + TV + N G
Sbjct: 403 RQERVGLLSLPLDPTLEPAC-LSFWYHMYGENVHKLSINISNDQNMEKTVFQKE-GNYGD 460
Query: 413 QWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDI 449
W + L + F ++ + I + A+DDI
Sbjct: 461 NWNYGQVTLNE-TVKFKVAFNAFKNKILSDI-ALDDI 495
Score = 39.3 bits (90), Expect = 0.035
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C AD F C +G+C+ ++CD C D SDE
Sbjct: 643 CKADHFQCKNGECVPLVNLCDGHLHCEDGSDE 674
Score = 39.3 bits (90), Expect = 0.035
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 8/68 (11%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHY----TSTTGSCNFETSSGNWTTACS-- 1453
F C++ +C+ LCD C D SDEA C + T+ G F S W TAC+
Sbjct: 648 FQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQS-IWHTACAEN 706
Query: 1454 -LTQDSED 1460
TQ S D
Sbjct: 707 WTTQISND 714
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 1654 PPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELIC---SNKSCSNGALV 1702
P C F C EC+P + LCDG C DE C N + +N LV
Sbjct: 640 PEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLV 691
Score = 36.2 bits (82), Expect = 0.30
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 1575 VAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCD 1634
V F DL+ + LD ++ T T G V ++ C C L C+ CD
Sbjct: 153 VTFHIDLNSVD----ILDKLTTTSHLATPGNVSIE---CLPGSSPCTDALTCIKADLFCD 205
Query: 1635 GHEDCIDGSDE 1645
G +C DGSDE
Sbjct: 206 GEVNCPDGSDE 216
Score = 36.2 bits (82), Expect = 0.30
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
P C + F C++ G C+ + CD C D SDEA CV
Sbjct: 640 PEPCKADHFQCKN-GECVPLVNLCDGHLHCEDGSDEADCV 678
Score = 33.5 bits (75), Expect = 1.9
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 3/45 (6%)
Query: 74 CSADEFPCTSG-QCIAKESVCDSRQDCSDESDEDPATCSKHLTCD 117
C PCT CI + CD +C D SDED C+ CD
Sbjct: 184 CLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCA--TVCD 226
Score = 32.7 bits (73), Expect = 3.3
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Query: 1114 LAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
L +P P C + +C NG+C L C+ +C D +DE +C
Sbjct: 637 LGIPEP---CKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADC 677
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
Query: 1160 SCTFEKGWCGWQNSQADNFDWVLGVGSHQS--LRPPKDHTLGNENAILL 1206
+C FE G+C W D+ +W GS S P DHT GN + +
Sbjct: 346 NCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYI 394
>gi|65301164 very low density lipoprotein receptor isoform b [Homo
sapiens]
Length = 845
Score = 98.6 bits (244), Expect = 5e-20
Identities = 52/125 (41%), Positives = 66/125 (52%), Gaps = 9/125 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
CE QF C +C+ L KCDG EDC+DGSDE +C C+ +F C+ +C+PS
Sbjct: 33 CEPSQFQCTNG-RCITLLWKCDGDEDCVDGSDEKNC----VKKTCAESDFVCNNGQCVPS 87
Query: 1673 LLLCDGVPDCHFNEDEL--ICSNKSCSNGALVC-ASSNSCIPAHQRCDGFADCMDFQLDE 1729
CDG PDC DE C ++C + C A S CIP RCDG DC D DE
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDC-DSGEDE 146
Query: 1730 SSCSD 1734
+C +
Sbjct: 147 ENCGN 151
Score = 92.4 bits (228), Expect = 4e-18
Identities = 53/137 (38%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 1598 PECVTGG---PVPVQPSPCEADQFSC-IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPT 1653
P+C G P C + SC ++ QC+P+S +CDG DC G DE +C
Sbjct: 95 PDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNIT- 153
Query: 1654 PPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAH 1713
CS EF CS+ CI +C+G DC DEL C+ +C C S++SCIP
Sbjct: 154 ---CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQC-STSSCIPIS 209
Query: 1714 QRCDGFADCMDFQLDES 1730
CD ADC D Q DES
Sbjct: 210 WVCDDDADCSD-QSDES 225
Score = 87.8 bits (216), Expect = 9e-17
Identities = 50/136 (36%), Positives = 64/136 (47%), Gaps = 6/136 (4%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEM--DCPLSPT-PPLCSNMEFPCST 1666
P C A +F C T C+P+S CD DC D SDE C P C E C +
Sbjct: 190 PPTCGAHEFQCS-TSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGS 248
Query: 1667 DECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQ 1726
ECI CDG PDC DE+ C +++C C SCI ++C+G DC+D
Sbjct: 249 GECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFEC-EDGSCIHGSRQCNGIRDCVDGS 307
Query: 1727 LDESSCSDTWTLLGIG 1742
DE +C + LG G
Sbjct: 308 -DEVNCKNVNQCLGPG 322
Score = 80.1 bits (196), Expect = 2e-14
Identities = 88/355 (24%), Positives = 123/355 (34%), Gaps = 66/355 (18%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTA---C 1452
E + F C + +CI CD DC D SDE +C T +F ++G + C
Sbjct: 34 EPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV--KKTCAESDFVCNNGQCVPSRWKC 91
Query: 1453 SLTQDSEDDLDWA-------------IGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKE 1499
D ED D + I + IP S G SG E
Sbjct: 92 DGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGEND-----CDSGEDE 146
Query: 1500 GSVARITTS-KSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRT 1558
+ IT S F S G C R + + N +
Sbjct: 147 ENCGNITCSPDEFTCSSGRCISR-----------------------------NFVCNGQD 177
Query: 1559 GWTYGSVPLSSNSPFKVAFEADLDGNEDI---FIALDDISFTPECVTG----GPVPVQPS 1611
+ GS L P A E + I ++ DD + + G PV +
Sbjct: 178 DCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHT 237
Query: 1612 PCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C A + C + +C+ +CDG DC DGSDE++CP C +F C CI
Sbjct: 238 KCPASEIQC-GSGECIHKKWRCDGDPDCKDGSDEVNCP----SRTCRPDQFECEDGSCIH 292
Query: 1672 SLLLCDGVPDCHFNEDELICSN-KSCSNGALVCASSNSCIPAHQRCDGFADCMDF 1725
C+G+ DC DE+ C N C S CI + C+ DC D+
Sbjct: 293 GSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDW 347
Score = 71.2 bits (173), Expect = 8e-12
Identities = 94/364 (25%), Positives = 134/364 (36%), Gaps = 54/364 (14%)
Query: 1390 ISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNF-ETSSGNW 1448
+ + C E +DF+C + +C+ S CD PDC D SDE+ + T C E S G
Sbjct: 68 VKKTCAE-SDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRT---CRIHEISCGAH 123
Query: 1449 TTAC---SLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQ----HFLYVN----SSGS 1497
+T C S D E+D D + T SG+ +F+ S GS
Sbjct: 124 STQCIPVSWRCDGENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGS 183
Query: 1498 KEGSVARITT-SKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNK 1556
E A T + F S C W D ++E+ G ++
Sbjct: 184 DELDCAPPTCGAHEFQCSTSSCIPISWV-CDDDADCSDQSDESLEQCGRQPVI------- 235
Query: 1557 RTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPS-PCEA 1615
T + S + D D P+C G PS C
Sbjct: 236 HTKCPASEIQCGSGECIHKKWRCDGD---------------PDCKDGSDEVNCPSRTCRP 280
Query: 1616 DQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLL 1675
DQF C C+ S +C+G DC+DGSDE++C +F C + ECI +
Sbjct: 281 DQFEC-EDGSCIHGSRQCNGIRDCVDGSDEVNC--KNVNQCLGPGKFKCRSGECIDISKV 337
Query: 1676 CDGVPDCHFNEDELI--CSNKSC--SNGALVCASSNSCIPAHQRCDGFADCMDFQL-DES 1730
C+ DC DE + C C +NG C+ + CD A F+L D
Sbjct: 338 CNQEQDCRDWSDEPLKECHINECLVNNGG--CSHICKDLVIGYECDCAA---GFELIDRK 392
Query: 1731 SCSD 1734
+C D
Sbjct: 393 TCGD 396
Score = 53.5 bits (127), Expect = 2e-06
Identities = 23/43 (53%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE---DPATCSKH 113
CS DEF C+SG+CI++ VC+ + DCSD SDE P TC H
Sbjct: 154 CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAH 196
Score = 48.9 bits (115), Expect = 4e-05
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+K C+ +F C +GQC+ CD DC D SDE P C TC CG
Sbjct: 69 KKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMR-TCRIHEISCG 121
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 12/110 (10%)
Query: 1388 GEISELCPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFET 1443
GE E C IT +F C +CI+ + +C+ + DCSD SDE CA T G+ F+
Sbjct: 143 GEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCA--PPTCGAHEFQC 200
Query: 1444 SSGNW---TTACSLTQDSEDDLDWAI---GSRIPAKALIPDSDHTPGSGQ 1487
S+ + + C D D D ++ G + P S+ GSG+
Sbjct: 201 STSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGE 250
Score = 46.2 bits (108), Expect = 3e-04
Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK----HLTCDFESGFCG 124
C A EF C++ CI VCD DCSD+SDE C + H C CG
Sbjct: 193 CGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCG 247
Score = 44.7 bits (104), Expect = 8e-04
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 676 PPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKR 735
P E+ T C ++F C ++G CI + KCD DC D SDE +CV + C+ E
Sbjct: 19 PRESGATGTGRKAKCEPSQFQC-TNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCA-ESD 76
Query: 736 SLCKWYQPIP 745
+C Q +P
Sbjct: 77 FVCNNGQCVP 86
Score = 42.4 bits (98), Expect = 0.004
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP------ELQCNFE-----TGICNWE 515
D F C R CI + +C+ DDC D +DE++CAP E QC+ + +C+ +
Sbjct: 157 DEFTCSSGR-CISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDD 215
Query: 516 QDAKDDFDWTRSQ-GPTPTLNT 536
D D D + Q G P ++T
Sbjct: 216 ADCSDQSDESLEQCGRQPVIHT 237
Score = 40.0 bits (92), Expect = 0.021
Identities = 17/32 (53%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C A E C SG+CI K+ CD DC D SDE
Sbjct: 239 CPASEIQCGSGECIHKKWRCDGDPDCKDGSDE 270
Score = 39.7 bits (91), Expect = 0.027
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA--SCVMEVCSFEKRS 736
C +++F+C ++G C+ KCD DC D SDE+ C M C + S
Sbjct: 72 CAESDFVC-NNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEIS 119
Score = 39.7 bits (91), Expect = 0.027
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 5/48 (10%)
Query: 893 DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
DC+P C HEF C+ CI +CD DC+D SDE+ C
Sbjct: 187 DCAP-----PTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQC 229
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 14/86 (16%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT------------FICRTSSGRC 947
P R C +F C + CI + C+ + DC D SDE F CR SG C
Sbjct: 274 PSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCR--SGEC 331
Query: 948 DFEFDLCSWKQEKDEDFDWNLKASSI 973
+C+ +Q+ + D LK I
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHI 357
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 15/75 (20%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQC----NFE------ 508
P+ +C D F C +CI R C+ + DC D +DEVNC QC F+
Sbjct: 274 PSRTCRP-DQFECEDG-SCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGEC 331
Query: 509 ---TGICNWEQDAKD 520
+ +CN EQD +D
Sbjct: 332 IDISKVCNQEQDCRD 346
Score = 39.3 bits (90), Expect = 0.035
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFC 123
+F C SG+CI VC+ QDC D SDE C H+ C +G C
Sbjct: 323 KFKCRSGECIDISKVCNQEQDCRDWSDEPLKEC--HINECLVNNGGC 367
Score = 38.9 bits (89), Expect = 0.046
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLL 749
C+ +EF C S G CI + C+ + DC D SDE C C + C IP+ +
Sbjct: 154 CSPDEFTC-SSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQ-CSTSSCIPISWV 211
Query: 750 QDSN 753
D +
Sbjct: 212 CDDD 215
Score = 38.5 bits (88), Expect = 0.060
Identities = 16/38 (42%), Positives = 21/38 (55%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
T + C +F CT+G+CI CD +DC D SDE
Sbjct: 27 TGRKAKCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDE 64
Score = 38.5 bits (88), Expect = 0.060
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 8/73 (10%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGR-----CDFEFDLC- 954
++ C + +F+C N C+ CD DC D SDE+ C + R C C
Sbjct: 69 KKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCI 128
Query: 955 --SWKQEKDEDFD 965
SW+ + + D D
Sbjct: 129 PVSWRCDGENDCD 141
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C +E C S G CI K +CD DC D SDE +C C
Sbjct: 239 CPASEIQCGS-GECIHKKWRCDGDPDCKDGSDEVNCPSRTC 278
Score = 38.5 bits (88), Expect = 0.060
Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 674 PTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
P + S V P C ++F C DG CI ++C+ DC D SDE +C
Sbjct: 262 PDCKDGSDEVNCPSRTCRPDQFECE-DGSCIHGSRQCNGIRDCVDGSDEVNC 312
Score = 37.7 bits (86), Expect = 0.10
Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 10/51 (19%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDET----------TFICRTSS 944
C+ EF C++ CI+++ +C+ +DC+D SDE F C TSS
Sbjct: 154 CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSS 204
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 5/70 (7%)
Query: 878 ISYIGDVAVD-----DISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADN 932
IS++ D D D S + C KC E C + CI K CD DC D
Sbjct: 208 ISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDG 267
Query: 933 SDETTFICRT 942
SDE RT
Sbjct: 268 SDEVNCPSRT 277
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 12/69 (17%)
Query: 903 KCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCS------- 955
KC +F C N CI CD DC D SDE + +T + DF +C+
Sbjct: 32 KCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCA-ESDF---VCNNGQCVPS 87
Query: 956 -WKQEKDED 963
WK + D D
Sbjct: 88 RWKCDGDPD 96
Score = 35.8 bits (81), Expect = 0.39
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
+ C D+F C G CI C+ +DC D SDE
Sbjct: 276 RTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE 309
Score = 34.3 bits (77), Expect = 1.1
Identities = 30/96 (31%), Positives = 37/96 (38%), Gaps = 16/96 (16%)
Query: 882 GDVAVDDISFQDCSPLLSPERKCTDHEFMCA--NKHCIAKDKLCDFVNDCADNSDETT-- 937
GD +D S D SP R C HE C + CI CD NDC DE
Sbjct: 93 GDPDCEDGS--DESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCG 150
Query: 938 --------FICRTSSGRCDFEFDLCSWKQEKDEDFD 965
F C SSGRC +C+ + + + D
Sbjct: 151 NITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSD 184
Score = 33.1 bits (74), Expect = 2.5
Identities = 14/42 (33%), Positives = 20/42 (47%)
Query: 1116 VPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
V P+ C EC +G C + CN + +C D +DE C
Sbjct: 271 VNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC 312
Score = 32.0 bits (71), Expect = 5.6
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 10/70 (14%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICN--------WEQDAKD 520
F C + R CI L CD +DC D +DE NC + C +CN W+ D
Sbjct: 38 FQCTNGR-CITLLWKCDGDEDCVDGSDEKNCVKK-TCAESDFVCNNGQCVPSRWKCDGDP 95
Query: 521 DFDWTRSQGP 530
D + + P
Sbjct: 96 DCEDGSDESP 105
Score = 32.0 bits (71), Expect = 5.6
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 11/75 (14%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI-----CNWEQDAKDDFDWT 525
CI K CD DC D +DEVNC + +C + I CN +D D D
Sbjct: 251 CIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEV 310
Query: 526 RSQGPTPTLNTGPMK 540
+ L G K
Sbjct: 311 NCKNVNQCLGPGKFK 325
Score = 32.0 bits (71), Expect = 5.6
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 438 GIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEV 497
GI D V D++ +N C G F CR + CI+ ++C+ DC D +DE
Sbjct: 299 GIRDCVDGSDEVNCKN------VNQCLGPGKFKCR-SGECIDISKVCNQEQDCRDWSDE- 350
Query: 498 NCAPELQCNFETGICN 513
P +C+ + N
Sbjct: 351 ---PLKECHINECLVN 363
Score = 31.6 bits (70), Expect = 7.4
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C +C NG+C L C+ ++C D +DE C
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNC 67
Score = 31.2 bits (69), Expect = 9.6
Identities = 11/28 (39%), Positives = 16/28 (57%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C +G+C CN D+C D +DE +C
Sbjct: 161 CSSGRCISRNFVCNGQDDCSDGSDELDC 188
>gi|65301167 very low density lipoprotein receptor isoform a [Homo
sapiens]
Length = 873
Score = 98.6 bits (244), Expect = 5e-20
Identities = 52/125 (41%), Positives = 66/125 (52%), Gaps = 9/125 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
CE QF C +C+ L KCDG EDC+DGSDE +C C+ +F C+ +C+PS
Sbjct: 33 CEPSQFQCTNG-RCITLLWKCDGDEDCVDGSDEKNC----VKKTCAESDFVCNNGQCVPS 87
Query: 1673 LLLCDGVPDCHFNEDEL--ICSNKSCSNGALVC-ASSNSCIPAHQRCDGFADCMDFQLDE 1729
CDG PDC DE C ++C + C A S CIP RCDG DC D DE
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDC-DSGEDE 146
Query: 1730 SSCSD 1734
+C +
Sbjct: 147 ENCGN 151
Score = 92.4 bits (228), Expect = 4e-18
Identities = 53/137 (38%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 1598 PECVTGG---PVPVQPSPCEADQFSC-IYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPT 1653
P+C G P C + SC ++ QC+P+S +CDG DC G DE +C
Sbjct: 95 PDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNIT- 153
Query: 1654 PPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAH 1713
CS EF CS+ CI +C+G DC DEL C+ +C C S++SCIP
Sbjct: 154 ---CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQC-STSSCIPIS 209
Query: 1714 QRCDGFADCMDFQLDES 1730
CD ADC D Q DES
Sbjct: 210 WVCDDDADCSD-QSDES 225
Score = 87.8 bits (216), Expect = 9e-17
Identities = 50/136 (36%), Positives = 64/136 (47%), Gaps = 6/136 (4%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEM--DCPLSPT-PPLCSNMEFPCST 1666
P C A +F C T C+P+S CD DC D SDE C P C E C +
Sbjct: 190 PPTCGAHEFQCS-TSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGS 248
Query: 1667 DECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQ 1726
ECI CDG PDC DE+ C +++C C SCI ++C+G DC+D
Sbjct: 249 GECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFEC-EDGSCIHGSRQCNGIRDCVDGS 307
Query: 1727 LDESSCSDTWTLLGIG 1742
DE +C + LG G
Sbjct: 308 -DEVNCKNVNQCLGPG 322
Score = 80.1 bits (196), Expect = 2e-14
Identities = 88/355 (24%), Positives = 123/355 (34%), Gaps = 66/355 (18%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTA---C 1452
E + F C + +CI CD DC D SDE +C T +F ++G + C
Sbjct: 34 EPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV--KKTCAESDFVCNNGQCVPSRWKC 91
Query: 1453 SLTQDSEDDLDWA-------------IGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKE 1499
D ED D + I + IP S G SG E
Sbjct: 92 DGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGEND-----CDSGEDE 146
Query: 1500 GSVARITTS-KSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRT 1558
+ IT S F S G C R + + N +
Sbjct: 147 ENCGNITCSPDEFTCSSGRCISR-----------------------------NFVCNGQD 177
Query: 1559 GWTYGSVPLSSNSPFKVAFEADLDGNEDI---FIALDDISFTPECVTG----GPVPVQPS 1611
+ GS L P A E + I ++ DD + + G PV +
Sbjct: 178 DCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHT 237
Query: 1612 PCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C A + C + +C+ +CDG DC DGSDE++CP C +F C CI
Sbjct: 238 KCPASEIQC-GSGECIHKKWRCDGDPDCKDGSDEVNCP----SRTCRPDQFECEDGSCIH 292
Query: 1672 SLLLCDGVPDCHFNEDELICSN-KSCSNGALVCASSNSCIPAHQRCDGFADCMDF 1725
C+G+ DC DE+ C N C S CI + C+ DC D+
Sbjct: 293 GSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDW 347
Score = 71.2 bits (173), Expect = 8e-12
Identities = 94/364 (25%), Positives = 134/364 (36%), Gaps = 54/364 (14%)
Query: 1390 ISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNF-ETSSGNW 1448
+ + C E +DF+C + +C+ S CD PDC D SDE+ + T C E S G
Sbjct: 68 VKKTCAE-SDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRT---CRIHEISCGAH 123
Query: 1449 TTAC---SLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQ----HFLYVN----SSGS 1497
+T C S D E+D D + T SG+ +F+ S GS
Sbjct: 124 STQCIPVSWRCDGENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGS 183
Query: 1498 KEGSVARITT-SKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNK 1556
E A T + F S C W D ++E+ G ++
Sbjct: 184 DELDCAPPTCGAHEFQCSTSSCIPISWV-CDDDADCSDQSDESLEQCGRQPVI------- 235
Query: 1557 RTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPS-PCEA 1615
T + S + D D P+C G PS C
Sbjct: 236 HTKCPASEIQCGSGECIHKKWRCDGD---------------PDCKDGSDEVNCPSRTCRP 280
Query: 1616 DQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLL 1675
DQF C C+ S +C+G DC+DGSDE++C +F C + ECI +
Sbjct: 281 DQFEC-EDGSCIHGSRQCNGIRDCVDGSDEVNC--KNVNQCLGPGKFKCRSGECIDISKV 337
Query: 1676 CDGVPDCHFNEDELI--CSNKSC--SNGALVCASSNSCIPAHQRCDGFADCMDFQL-DES 1730
C+ DC DE + C C +NG C+ + CD A F+L D
Sbjct: 338 CNQEQDCRDWSDEPLKECHINECLVNNGG--CSHICKDLVIGYECDCAA---GFELIDRK 392
Query: 1731 SCSD 1734
+C D
Sbjct: 393 TCGD 396
Score = 53.5 bits (127), Expect = 2e-06
Identities = 23/43 (53%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE---DPATCSKH 113
CS DEF C+SG+CI++ VC+ + DCSD SDE P TC H
Sbjct: 154 CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAH 196
Score = 48.9 bits (115), Expect = 4e-05
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+K C+ +F C +GQC+ CD DC D SDE P C TC CG
Sbjct: 69 KKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMR-TCRIHEISCG 121
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 12/110 (10%)
Query: 1388 GEISELCPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFET 1443
GE E C IT +F C +CI+ + +C+ + DCSD SDE CA T G+ F+
Sbjct: 143 GEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCA--PPTCGAHEFQC 200
Query: 1444 SSGNW---TTACSLTQDSEDDLDWAI---GSRIPAKALIPDSDHTPGSGQ 1487
S+ + + C D D D ++ G + P S+ GSG+
Sbjct: 201 STSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGE 250
Score = 46.2 bits (108), Expect = 3e-04
Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK----HLTCDFESGFCG 124
C A EF C++ CI VCD DCSD+SDE C + H C CG
Sbjct: 193 CGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCG 247
Score = 44.7 bits (104), Expect = 8e-04
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 676 PPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKR 735
P E+ T C ++F C ++G CI + KCD DC D SDE +CV + C+ E
Sbjct: 19 PRESGATGTGRKAKCEPSQFQC-TNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCA-ESD 76
Query: 736 SLCKWYQPIP 745
+C Q +P
Sbjct: 77 FVCNNGQCVP 86
Score = 42.4 bits (98), Expect = 0.004
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP------ELQCNFE-----TGICNWE 515
D F C R CI + +C+ DDC D +DE++CAP E QC+ + +C+ +
Sbjct: 157 DEFTCSSGR-CISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDD 215
Query: 516 QDAKDDFDWTRSQ-GPTPTLNT 536
D D D + Q G P ++T
Sbjct: 216 ADCSDQSDESLEQCGRQPVIHT 237
Score = 40.0 bits (92), Expect = 0.021
Identities = 17/32 (53%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C A E C SG+CI K+ CD DC D SDE
Sbjct: 239 CPASEIQCGSGECIHKKWRCDGDPDCKDGSDE 270
Score = 39.7 bits (91), Expect = 0.027
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA--SCVMEVCSFEKRS 736
C +++F+C ++G C+ KCD DC D SDE+ C M C + S
Sbjct: 72 CAESDFVC-NNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEIS 119
Score = 39.7 bits (91), Expect = 0.027
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 5/48 (10%)
Query: 893 DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
DC+P C HEF C+ CI +CD DC+D SDE+ C
Sbjct: 187 DCAP-----PTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQC 229
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 14/86 (16%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT------------FICRTSSGRC 947
P R C +F C + CI + C+ + DC D SDE F CR SG C
Sbjct: 274 PSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCR--SGEC 331
Query: 948 DFEFDLCSWKQEKDEDFDWNLKASSI 973
+C+ +Q+ + D LK I
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHI 357
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 15/75 (20%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQC----NFE------ 508
P+ +C D F C +CI R C+ + DC D +DEVNC QC F+
Sbjct: 274 PSRTCRP-DQFECEDG-SCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGEC 331
Query: 509 ---TGICNWEQDAKD 520
+ +CN EQD +D
Sbjct: 332 IDISKVCNQEQDCRD 346
Score = 39.3 bits (90), Expect = 0.035
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFC 123
+F C SG+CI VC+ QDC D SDE C H+ C +G C
Sbjct: 323 KFKCRSGECIDISKVCNQEQDCRDWSDEPLKEC--HINECLVNNGGC 367
Score = 38.9 bits (89), Expect = 0.046
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLL 749
C+ +EF C S G CI + C+ + DC D SDE C C + C IP+ +
Sbjct: 154 CSPDEFTC-SSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQ-CSTSSCIPISWV 211
Query: 750 QDSN 753
D +
Sbjct: 212 CDDD 215
Score = 38.5 bits (88), Expect = 0.060
Identities = 16/38 (42%), Positives = 21/38 (55%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
T + C +F CT+G+CI CD +DC D SDE
Sbjct: 27 TGRKAKCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDE 64
Score = 38.5 bits (88), Expect = 0.060
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 8/73 (10%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGR-----CDFEFDLC- 954
++ C + +F+C N C+ CD DC D SDE+ C + R C C
Sbjct: 69 KKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCI 128
Query: 955 --SWKQEKDEDFD 965
SW+ + + D D
Sbjct: 129 PVSWRCDGENDCD 141
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C +E C S G CI K +CD DC D SDE +C C
Sbjct: 239 CPASEIQCGS-GECIHKKWRCDGDPDCKDGSDEVNCPSRTC 278
Score = 38.5 bits (88), Expect = 0.060
Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 674 PTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
P + S V P C ++F C DG CI ++C+ DC D SDE +C
Sbjct: 262 PDCKDGSDEVNCPSRTCRPDQFECE-DGSCIHGSRQCNGIRDCVDGSDEVNC 312
Score = 37.7 bits (86), Expect = 0.10
Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 10/51 (19%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDET----------TFICRTSS 944
C+ EF C++ CI+++ +C+ +DC+D SDE F C TSS
Sbjct: 154 CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSS 204
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 5/70 (7%)
Query: 878 ISYIGDVAVD-----DISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADN 932
IS++ D D D S + C KC E C + CI K CD DC D
Sbjct: 208 ISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDG 267
Query: 933 SDETTFICRT 942
SDE RT
Sbjct: 268 SDEVNCPSRT 277
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 12/69 (17%)
Query: 903 KCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCS------- 955
KC +F C N CI CD DC D SDE + +T + DF +C+
Sbjct: 32 KCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCA-ESDF---VCNNGQCVPS 87
Query: 956 -WKQEKDED 963
WK + D D
Sbjct: 88 RWKCDGDPD 96
Score = 35.8 bits (81), Expect = 0.39
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
+ C D+F C G CI C+ +DC D SDE
Sbjct: 276 RTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE 309
Score = 34.3 bits (77), Expect = 1.1
Identities = 30/96 (31%), Positives = 37/96 (38%), Gaps = 16/96 (16%)
Query: 882 GDVAVDDISFQDCSPLLSPERKCTDHEFMCA--NKHCIAKDKLCDFVNDCADNSDETT-- 937
GD +D S D SP R C HE C + CI CD NDC DE
Sbjct: 93 GDPDCEDGS--DESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCG 150
Query: 938 --------FICRTSSGRCDFEFDLCSWKQEKDEDFD 965
F C SSGRC +C+ + + + D
Sbjct: 151 NITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSD 184
Score = 33.1 bits (74), Expect = 2.5
Identities = 14/42 (33%), Positives = 20/42 (47%)
Query: 1116 VPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
V P+ C EC +G C + CN + +C D +DE C
Sbjct: 271 VNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC 312
Score = 32.0 bits (71), Expect = 5.6
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 10/70 (14%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICN--------WEQDAKD 520
F C + R CI L CD +DC D +DE NC + C +CN W+ D
Sbjct: 38 FQCTNGR-CITLLWKCDGDEDCVDGSDEKNCVKK-TCAESDFVCNNGQCVPSRWKCDGDP 95
Query: 521 DFDWTRSQGP 530
D + + P
Sbjct: 96 DCEDGSDESP 105
Score = 32.0 bits (71), Expect = 5.6
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 11/75 (14%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI-----CNWEQDAKDDFDWT 525
CI K CD DC D +DEVNC + +C + I CN +D D D
Sbjct: 251 CIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEV 310
Query: 526 RSQGPTPTLNTGPMK 540
+ L G K
Sbjct: 311 NCKNVNQCLGPGKFK 325
Score = 32.0 bits (71), Expect = 5.6
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 438 GIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEV 497
GI D V D++ +N C G F CR + CI+ ++C+ DC D +DE
Sbjct: 299 GIRDCVDGSDEVNCKN------VNQCLGPGKFKCR-SGECIDISKVCNQEQDCRDWSDE- 350
Query: 498 NCAPELQCNFETGICN 513
P +C+ + N
Sbjct: 351 ---PLKECHINECLVN 363
Score = 31.6 bits (70), Expect = 7.4
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C +C NG+C L C+ ++C D +DE C
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNC 67
Score = 31.2 bits (69), Expect = 9.6
Identities = 11/28 (39%), Positives = 16/28 (57%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C +G+C CN D+C D +DE +C
Sbjct: 161 CSSGRCISRNFVCNGQDDCSDGSDELDC 188
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 95.9 bits (237), Expect = 3e-19
Identities = 50/127 (39%), Positives = 66/127 (51%), Gaps = 6/127 (4%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE-CIP 1671
C + QF C +C+P++ +C+G +DC D DE DCP + CS F C T + CI
Sbjct: 3396 CLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENS----CSPDYFQCKTTKHCIS 3451
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
L +CD PDC DE C K+C C +N+CIP H RCD DC D +E+
Sbjct: 3452 KLWVCDEDPDCADASDEANCDKKTCGPHEFQC-KNNNCIPDHWRCDSQNDCSDNSDEENC 3510
Query: 1732 CSDTWTL 1738
T TL
Sbjct: 3511 KPQTCTL 3517
Score = 94.0 bits (232), Expect = 1e-18
Identities = 52/125 (41%), Positives = 62/125 (49%), Gaps = 7/125 (5%)
Query: 1611 SPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMD-CPLSPTPPLCSNMEFPCSTDEC 1669
S C A QF C T +C+P KCD +DC DGSDE D CP C F C T C
Sbjct: 3315 SNCTASQFRC-KTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFR----CQPGRFQCGTGLC 3369
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDE 1729
+CDG DC N DEL C C +G C + CIP + RC+G DC D + DE
Sbjct: 3370 ALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGD-EEDE 3428
Query: 1730 SSCSD 1734
C +
Sbjct: 3429 RDCPE 3433
Score = 90.5 bits (223), Expect = 1e-17
Identities = 51/126 (40%), Positives = 65/126 (51%), Gaps = 10/126 (7%)
Query: 1609 QPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE 1668
+P C F C CV CDG DC DGSDE +C S CS +F CS +
Sbjct: 3511 KPQTCTLKDFLCANG-DCVSSRFWCDGDFDCADGSDERNCETS-----CSKDQFRCSNGQ 3564
Query: 1669 CIPSLLLCDGVPDCHFNEDELIC--SNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQ 1726
CIP+ CDG DC + EDE C ++ +CS+ +CA S+ CI A +C+G DC D
Sbjct: 3565 CIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICA-SDGCISASLKCNGEYDCADGS 3623
Query: 1727 LDESSC 1732
DE C
Sbjct: 3624 -DEMDC 3628
Score = 85.1 bits (209), Expect = 6e-16
Identities = 93/385 (24%), Positives = 135/385 (35%), Gaps = 76/385 (19%)
Query: 1400 FLC-RDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACS----L 1454
F C +++KCI +L C+ + DC D DE C SC+ + T C +
Sbjct: 3401 FKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPE-----NSCSPDYFQCKTTKHCISKLWV 3455
Query: 1455 TQDSEDDLDWAIGSRIPAKALIPDS----------DHTPGSGQHFLYVNSSGSKEGSVAR 1504
+ D D + + K P DH Q+ NS +E +
Sbjct: 3456 CDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSD--EENCKPQ 3513
Query: 1505 ITTSKSFPASLGMC-TVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYG 1563
T K F + G C + RFW + + S N T +
Sbjct: 3514 TCTLKDFLCANGDCVSSRFWC-----------------DGDFDCADGSDERNCETSCSKD 3556
Query: 1564 SVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTP------------------------- 1598
S+ ++ D G+ED D+ S P
Sbjct: 3557 QFRCSNGQCIPAKWKCD--GHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCN 3614
Query: 1599 ---ECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPP 1655
+C G + C+ DQF C C+P+ CDG DC+DGSDE +C
Sbjct: 3615 GEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGN-- 3672
Query: 1656 LCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDEL--ICSNKSC-SNGALVCASSNSCIPA 1712
+C EF C+ C +CDG DC N DE +C C S C ++ C+ +
Sbjct: 3673 ICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQS 3732
Query: 1713 HQRCDGFADCMDFQLDESSCSDTWT 1737
Q C+G +C D DE C T
Sbjct: 3733 EQMCNGIDECGD-NSDEDHCGGKLT 3756
Score = 84.3 bits (207), Expect = 1e-15
Identities = 48/133 (36%), Positives = 64/133 (48%), Gaps = 6/133 (4%)
Query: 1602 TGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNME 1661
T P P C+A +F C C+ KCDG +DC+DGSDE ++ C + +
Sbjct: 834 TFNPGEALPHICKAGEFRC-KNRHCIQARWKCDGDDDCLDGSDEDS--VNCFNHSCPDDQ 890
Query: 1662 FPCSTDECIPSLLLCDGVPDCHFNEDE--LICSNKSCSNGALVCASSNSCIPAHQRCDGF 1719
F C + CIP LCDG DC NEDE C+ ++C C + CIP CD
Sbjct: 891 FKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGR-CIPRAWLCDRE 949
Query: 1720 ADCMDFQLDESSC 1732
DC D + +SC
Sbjct: 950 DDCGDQTDEMASC 962
Score = 84.3 bits (207), Expect = 1e-15
Identities = 94/344 (27%), Positives = 128/344 (37%), Gaps = 86/344 (25%)
Query: 1394 CPEITD----FLCRDKK-CIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNW 1448
CPE + F C+ K CI+ +CD PDC+D SDEA+C T G F+ + N
Sbjct: 3431 CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCD--KKTCGPHEFQCKNNN- 3487
Query: 1449 TTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARITTS 1508
IP DH Q+ NS +E + T
Sbjct: 3488 --------------------------CIP--DHWRCDSQNDCSDNS--DEENCKPQTCTL 3517
Query: 1509 KSFPASLGMC-TVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPL 1567
K F + G C + RFW + + S N T +
Sbjct: 3518 KDFLCANGDCVSSRFWC-----------------DGDFDCADGSDERNCETSCSKDQFRC 3560
Query: 1568 SSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCV 1627
S+ ++ DG+ED D+ S P T C + ++ C + C+
Sbjct: 3561 SNGQCIPAKWKC--DGHEDCKYGEDEKSCEPASPT----------CSSREYICA-SDGCI 3607
Query: 1628 PLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTD-ECIPSLLLCDGVPDCHFNE 1686
S KC+G DC DGSDEMDC C +F C CIP LCDG+ DC
Sbjct: 3608 SASLKCNGEYDCADGSDEMDCVTE-----CKEDQFRCKNKAHCIPIRWLCDGIHDCVDGS 3662
Query: 1687 DELICSNKSCSNGALVCAS-----SNSCIPAH-QRCDGFADCMD 1724
DE ++C G +C + +NS H CDG DC D
Sbjct: 3663 DE-----ENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGD 3701
Score = 81.6 bits (200), Expect = 6e-15
Identities = 50/124 (40%), Positives = 63/124 (50%), Gaps = 8/124 (6%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEM-DCPLSPTPPLCSNMEFPCSTDECIP 1671
C+ DQFSC +C+P + CD +DC D +DEM C PL +F C + CI
Sbjct: 927 CQVDQFSC-GNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPL---TQFVCKSGRCIS 982
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
S CD DC DE+ C + SC + C SS CIP H CDG DC DF DE+
Sbjct: 983 SKWHCDSDDDCGDGSDEVGCVH-SCFDNQFRC-SSGRCIPGHWACDGDNDCGDFS-DEAQ 1039
Query: 1732 CSDT 1735
+ T
Sbjct: 1040 INCT 1043
Score = 81.6 bits (200), Expect = 6e-15
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 14/124 (11%)
Query: 1618 FSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCD 1677
F Y +C+P CDG DC D SDE+DC +S C+ +EF C+ CIP C+
Sbjct: 2556 FKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVST----CATVEFRCADGTCIPRSARCN 2611
Query: 1678 GVPDCHFNEDELICSNKSCSN---------GALVCASSNSCIPAHQRCDGFADCMDFQLD 1728
DC DE C+N C++ G + C S++ C+ CDG DC D+ D
Sbjct: 2612 QNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYS-D 2670
Query: 1729 ESSC 1732
E C
Sbjct: 2671 ELKC 2674
Score = 80.5 bits (197), Expect = 1e-14
Identities = 47/144 (32%), Positives = 56/144 (38%), Gaps = 11/144 (7%)
Query: 1582 DGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCID 1641
DG +D LD+ +T C AD FSC + CVP CDG DC D
Sbjct: 2740 DGEDDCGDGLDESDSICGAIT----------CAADMFSCQGSRACVPRHWLCDGERDCPD 2789
Query: 1642 GSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDEL-ICSNKSCSNGA 1700
GSDE+ C F C CIP +CD DC DE C + C
Sbjct: 2790 GSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEE 2849
Query: 1701 LVCASSNSCIPAHQRCDGFADCMD 1724
CA + +CDG DC D
Sbjct: 2850 FSCADGRCLLNTQWQCDGDFDCPD 2873
Score = 78.2 bits (191), Expect = 7e-14
Identities = 45/118 (38%), Positives = 59/118 (50%), Gaps = 5/118 (4%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSN-MEFPC-STD 1667
P+ C ++F C CVP +CDG +DC DGSDE C + T LC + +F C ST
Sbjct: 1050 PAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGC--NGTIRLCDHKTKFSCWSTG 1107
Query: 1668 ECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNS-CIPAHQRCDGFADCMD 1724
CI +CDG DC DE C + C CA+ S C+ + C+G DC D
Sbjct: 1108 RCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPD 1165
Score = 77.4 bits (189), Expect = 1e-13
Identities = 46/111 (41%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 1620 CIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGV 1679
C T CV + CDG DC D SDE+ CP+ C F C + CI + +CDG
Sbjct: 2646 CNSTSLCVLPTWICDGSNDCGDYSDELKCPVQ-NKHKCEENYFSCPSGRCILNTWICDGQ 2704
Query: 1680 PDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDES 1730
DC DE C + SCS C S+ CI H CDG DC D LDES
Sbjct: 2705 KDCEDGRDEFHC-DSSCSWNQFAC-SAQKCISKHWICDGEDDCGD-GLDES 2752
Score = 76.6 bits (187), Expect = 2e-13
Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 7/121 (5%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE-CIP 1671
C+ +F C L +P + CDG DC D SDE++C +C + +F C+ ++ CIP
Sbjct: 3357 CQPGRFQCGTGLCALP-AFICDGENDCGDNSDELNCDTH----VCLSGQFKCTKNQKCIP 3411
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
L C+G DC EDE C SCS C ++ CI CD DC D DE++
Sbjct: 3412 VNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADAS-DEAN 3470
Query: 1732 C 1732
C
Sbjct: 3471 C 3471
Score = 76.3 bits (186), Expect = 3e-13
Identities = 46/127 (36%), Positives = 58/127 (45%), Gaps = 15/127 (11%)
Query: 1617 QFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLC 1676
QF C + +C+ CD +DC DGSDE+ C S C + +F CS+ CIP C
Sbjct: 972 QFVC-KSGRCISSKWHCDSDDDCGDGSDEVGCVHS-----CFDNQFRCSSGRCIPGHWAC 1025
Query: 1677 DGVPDCHFNEDEL--------ICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLD 1728
DG DC DE I S C+ C +C+P RCDG DC D D
Sbjct: 1026 DGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGS-D 1084
Query: 1729 ESSCSDT 1735
E C+ T
Sbjct: 1085 EKGCNGT 1091
Score = 73.6 bits (179), Expect = 2e-12
Identities = 87/345 (25%), Positives = 123/345 (35%), Gaps = 73/345 (21%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDE--AHCAHYTSTTGSCNFETSSGNWTTACSLTQ 1456
+F C+++ CI + CD DC D SDE +C ++ SC
Sbjct: 849 EFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNH-----SC----------------- 886
Query: 1457 DSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLG 1516
DD +R K + D + GS N S + AR F G
Sbjct: 887 --PDDQFKCQNNRCIPKRWLCDGANDCGS-------NEDESNQTCTARTCQVDQFSCGNG 937
Query: 1517 MCTVRFWFY-MIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKV 1575
C R W D ++ + E L V + R +
Sbjct: 938 RCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRC----------------I 981
Query: 1576 AFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDG 1635
+ + D ++D D++ C +QF C + +C+P CDG
Sbjct: 982 SSKWHCDSDDDCGDGSDEVGCVHSCFD-------------NQFRC-SSGRCIPGHWACDG 1027
Query: 1636 HEDCIDGSDE--MDCPLSP--TPPLCSNMEFPCSTD-ECIPSLLLCDGVPDCHFNEDELI 1690
DC D SDE ++C +P C+ EF C D C+P L CDG DC DE
Sbjct: 1028 DNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKG 1087
Query: 1691 CSN--KSCSNGA-LVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
C+ + C + C S+ CI CDG DC D Q DE C
Sbjct: 1088 CNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCED-QSDEDDC 1131
Score = 73.6 bits (179), Expect = 2e-12
Identities = 89/365 (24%), Positives = 132/365 (36%), Gaps = 60/365 (16%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEA--HCAHYTSTTGS------------- 1438
C ++F C + +CI L CD P C D+SDE +C + + G
Sbjct: 2510 CNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGK 2569
Query: 1439 -CNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGS 1497
C+ E G D+ D+LD + + + D P S + ++ + +
Sbjct: 2570 LCDGENDCG----------DNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADA 2619
Query: 1498 KEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESG-----LNILVWSV 1552
+ T F LG+ T F + S+ +L + + S + L V
Sbjct: 2620 SDEKNCNNTDCTHF-YKLGVKTTGF--IRCNSTSLCVLPTWICDGSNDCGDYSDELKCPV 2676
Query: 1553 IGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSP 1612
+ Y S P S + DG +D D+ C S
Sbjct: 2677 QNKHKCEENYFSCP----SGRCILNTWICDGQKDCEDGRDEF----HC---------DSS 2719
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPC-STDECIP 1671
C +QF+C +C+ CDG +DC DG DE D C+ F C + C+P
Sbjct: 2720 CSWNQFACS-AQKCISKHWICDGEDDCGDGLDESDSICGAI--TCAADMFSCQGSRACVP 2776
Query: 1672 SLLLCDGVPDCHFNEDEL----ICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQL 1727
LCDG DC DEL N +C A +C + CIP CD DC D
Sbjct: 2777 RHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMC-HNKVCIPKQFVCDHDDDCGDGSD 2835
Query: 1728 DESSC 1732
+ C
Sbjct: 2836 ESPQC 2840
Score = 70.1 bits (170), Expect = 2e-11
Identities = 47/126 (37%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 1611 SPCEA-DQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDEC 1669
S C A +F C +C+ CDG C D SDE L C PC C
Sbjct: 2508 SSCNAYSEFEC-GNGECIDYQLTCDGIPHCKDKSDEK--LLYCENRSCRRGFKPCYNRRC 2564
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDE 1729
IP LCDG DC N DEL C +C+ CA +CIP RC+ DC D DE
Sbjct: 2565 IPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCA-DGTCIPRSARCNQNIDCADAS-DE 2622
Query: 1730 SSCSDT 1735
+C++T
Sbjct: 2623 KNCNNT 2628
Score = 64.3 bits (155), Expect = 1e-09
Identities = 70/274 (25%), Positives = 98/274 (35%), Gaps = 78/274 (28%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIP 745
P ++C+ + F C++ HCI K+ CD DC D SDEA+C + C CK IP
Sbjct: 3432 PENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCG-PHEFQCKNNNCIP 3490
Query: 746 VHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILT 805
H DS N S + EEN +P
Sbjct: 3491 DHWRCDSQ-------NDCSDNSDEENCKPQT----------------------------- 3514
Query: 806 PIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTG---QQGAQWKRAEVFL 862
CTL + NG D V+S+ W G+ + E
Sbjct: 3515 ---------CTLKDFLCANG------------DCVSSRFWCDGDFDCADGSDERNCET-- 3551
Query: 863 GIRSHTQIVFRAKRGISYIGDVAVD---DISF----QDCSPLLSPERKCTDHEFMCANKH 915
S ++ FR G D D + + C P SP C+ E++CA+
Sbjct: 3552 ---SCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEP-ASP--TCSSREYICASDG 3605
Query: 916 CIAKDKLCDFVNDCADNSDETTFI--CRTSSGRC 947
CI+ C+ DCAD SDE + C+ RC
Sbjct: 3606 CISASLKCNGEYDCADGSDEMDCVTECKEDQFRC 3639
Score = 60.1 bits (144), Expect = 2e-08
Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 21/140 (15%)
Query: 1603 GGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEF 1662
GG + + PC+ D+F+C +C+P+ +CD +DC DGSDE C ++PT C +
Sbjct: 3752 GGKLTYKARPCKKDEFACS-NKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVN 3810
Query: 1663 PCSTD---ECIPSLLLCDGVPDCHFNEDELICSN-------KSCSNGALVCASSNSCIPA 1712
PC D I + + C P N C + +CS+ + S C+
Sbjct: 3811 PCGDDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCV-- 3868
Query: 1713 HQRCDGFADCMDFQLDESSC 1732
CD +FQ ++C
Sbjct: 3869 ---CD-----QNFQERNNTC 3880
Score = 59.7 bits (143), Expect = 3e-08
Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 9/119 (7%)
Query: 1617 QFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE--CIPSLL 1674
+FSC T +C+ + CDG DC D SDE DC LC + PC+ D C+
Sbjct: 1100 KFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSF----LCGPPKHPCANDTSVCLQPEK 1155
Query: 1675 LCDGVPDCHFNEDE-LICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
LC+G DC DE +C S +NG C++ S +P + + D +C
Sbjct: 1156 LCNGKKDCPDGSDEGYLCDECSLNNGG--CSNHCSVVPGRGIVCSCPEGLQLNKDNKTC 1212
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSP----TPPLCSNMEFPCSTDE 1668
C ++FSC + +CDG DC D SDE PL+P C++ F C
Sbjct: 2845 CGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDE--APLNPKCKSAEQSCNSSFFMCKNGR 2902
Query: 1669 CIPSLLLCDGVPDCHFNEDELICSNKSC-SNGALVCASSNSCIPAHQRCDGFADCMDFQL 1727
CIPS LCD DC DE C C S C+ +P +C + FQL
Sbjct: 2903 CIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWP---GFQL 2959
Query: 1728 --DESSCSD 1734
D +C D
Sbjct: 2960 KDDGKTCVD 2968
Score = 51.2 bits (121), Expect = 9e-06
Identities = 41/128 (32%), Positives = 54/128 (42%), Gaps = 10/128 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE-MDCPLSPTPPLCSNMEFPC-STDECI 1670
C+ +F C + CV S CDG DC D SDE +D C C T++C+
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCV 91
Query: 1671 PSLLLCDGVPDCHFNEDELICSNKSCSN-GALVCASSNSCIPAHQRC---DGFADCMDFQ 1726
LC+GV DC DE + + SN L C + + RC DGF +
Sbjct: 92 HLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGF----EIT 147
Query: 1727 LDESSCSD 1734
D SC D
Sbjct: 148 EDGRSCKD 155
Score = 51.2 bits (121), Expect = 9e-06
Identities = 64/256 (25%), Positives = 89/256 (34%), Gaps = 57/256 (22%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEAS--CVMEVCSFEKRSLCKWYQPI 744
PH C EF C++ HCI+ KCD DC D SDE S C C + + C+ + I
Sbjct: 842 PHICKAGEFRCKNR-HCIQARWKCDGDDDCLDGSDEDSVNCFNHSCP-DDQFKCQNNRCI 899
Query: 745 PVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADIL 804
P L D N + E N
Sbjct: 900 PKRWLCDG-------ANDCGSNEDESNQ-------------------------------- 920
Query: 805 TPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGI 864
+ T C + ++ NG + + ++D+ G Q + E F
Sbjct: 921 ----TCTARTCQVDQFSCGNGRCIPRAWLCDREDDC--------GDQTDEMASCE-FPTC 967
Query: 865 RSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCD 924
TQ V ++ R IS DD D S + C D++F C++ CI CD
Sbjct: 968 EPLTQFVCKSGRCISSKWHCDSDD-DCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACD 1026
Query: 925 FVNDCADNSDETTFIC 940
NDC D SDE C
Sbjct: 1027 GDNDCGDFSDEAQINC 1042
Score = 50.8 bits (120), Expect = 1e-05
Identities = 34/99 (34%), Positives = 43/99 (43%), Gaps = 12/99 (12%)
Query: 447 DDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC------A 500
DD E P SC D+F C+ T+ CI KL +CD DC D +DE NC
Sbjct: 3420 DDCGDEEDERDCPENSCSP-DYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGP 3478
Query: 501 PELQCNFETGI-----CNWEQDAKDDFDWTRSQGPTPTL 534
E QC I C+ + D D+ D + T TL
Sbjct: 3479 HEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTL 3517
Score = 49.7 bits (117), Expect = 3e-05
Identities = 69/282 (24%), Positives = 105/282 (37%), Gaps = 37/282 (13%)
Query: 684 TLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVCSFEKRSLCKWYQ 742
T C ++F C +G CI + CD + DC D++DE ASC C + +CK +
Sbjct: 921 TCTARTCQVDQFSC-GNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGR 979
Query: 743 PIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTAD 802
I DS+ + + H +++ + W D+ G F D A
Sbjct: 980 CISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQ 1039
Query: 803 ILTPIISLTGPK-CT-LVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQ----GAQWK 856
I + P C F H +G N LW G++ G+ K
Sbjct: 1040 INCTKEEIHSPAGCNGNEFQCHPDG-------------NCVPDLWRCDGEKDCEDGSDEK 1086
Query: 857 RAEVFLGIRSHTQ--IVFRAKRGISYI----GDVAVDDISFQ-DCSPLLSPERKCTDHEF 909
+ + H + R I+ GD+ +D S + DC L C +
Sbjct: 1087 GCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFL-----CGPPKH 1141
Query: 910 MCAN--KHCIAKDKLCDFVNDCADNSDETTFI--CRTSSGRC 947
CAN C+ +KLC+ DC D SDE C ++G C
Sbjct: 1142 PCANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECSLNNGGC 1183
Score = 49.7 bits (117), Expect = 3e-05
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 887 DDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI----CRT 942
D++S C+P C ++ FMC NK CI K +CD +DC D SDE+ C T
Sbjct: 2792 DELSTAGCAP----NNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGT 2847
Query: 943 SSGRCDFEFDLCSWKQEKDEDFD 965
C L + + + D DFD
Sbjct: 2848 EEFSCADGRCLLNTQWQCDGDFD 2870
Score = 48.9 bits (115), Expect = 4e-05
Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 884 VAVDDISFQDCSPLLSPERK-CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT----- 937
V +D D S + ++K C HEF C N +CI CD NDC+DNSDE
Sbjct: 3455 VCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQT 3514
Query: 938 -----FICR-----TSSGRCDFEFDLCSWKQEKD 961
F+C +S CD +FD E++
Sbjct: 3515 CTLKDFLCANGDCVSSRFWCDGDFDCADGSDERN 3548
Score = 48.1 bits (113), Expect = 8e-05
Identities = 74/298 (24%), Positives = 112/298 (37%), Gaps = 65/298 (21%)
Query: 447 DDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEV------NCA 500
+D + CT A +C+ +D F C + R CI + LCD DDCGD+TDE+ C
Sbjct: 915 EDESNQTCT----ARTCQ-VDQFSCGNGR-CIPRAWLCDREDDCGDQTDEMASCEFPTCE 968
Query: 501 PELQCNFETGIC---NWEQDAKDDF-DWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIES 556
P Q ++G C W D+ DD D + G + + ++ GH+
Sbjct: 969 PLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGD 1028
Query: 557 SEPQAFQDSAALLSPILNATDTKGCT-FRFYYHMFGKRIYRLAIYQRIW----------- 604
++ F D A + GC F H G + +W
Sbjct: 1029 NDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCV------PDLWRCDGEKDCEDG 1082
Query: 605 SDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCTL 664
SD +G N R S + + +A V D GDI +D S D
Sbjct: 1083 SDEKG-------CNGTIRLCDHKTKFSCWSTGRCINKAWVCD---GDIDCEDQSDED--- 1129
Query: 665 YPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE 722
+ + L PP+ H C ++ + C++ + C+ K DCPD SDE
Sbjct: 1130 ---DCDSFLCGPPK---------HPCANDTSV------CLQPEKLCNGKKDCPDGSDE 1169
Score = 48.1 bits (113), Expect = 8e-05
Identities = 61/259 (23%), Positives = 106/259 (40%), Gaps = 32/259 (12%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV 746
P CT +F+C ++G C+ CD +DC D SDE +C E + + C Q IP
Sbjct: 3512 PQTCTLKDFLC-ANGDCVSSRFWCDGDFDCADGSDERNC--ETSCSKDQFRCSNGQCIPA 3568
Query: 747 HLLQDSNTFRWGLGNGISIHHGEENHR-----PSVDHTQN--TTDGWYLYADSSNGKFGD 799
+W +GE+ P+ + +DG + NG++ D
Sbjct: 3569 ---------KWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCNGEY-D 3618
Query: 800 TADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKK-DNVTSKLWAQTGQQGAQWKRA 858
AD + +T +C + N A ++ L + + ++G RA
Sbjct: 3619 CADGSDEMDCVT--ECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNICRA 3676
Query: 859 EVFLGIRSHTQIVFRAKRGISYIGDVAVD--DISFQDCSPLLSPERKCTDHEFMCANKHC 916
+ FL S ++ F G GD + + D+ + P P R C + N+ C
Sbjct: 3677 DEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRPHR-CRN------NRIC 3729
Query: 917 IAKDKLCDFVNDCADNSDE 935
+ +++C+ +++C DNSDE
Sbjct: 3730 LQSEQMCNGIDECGDNSDE 3748
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAH------YTSTTGSCNFETSSGN 1447
C +T F+C+ +CI+S CD DC D SDE C H + ++G C G+
Sbjct: 967 CEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRC----IPGH 1022
Query: 1448 WTTACSLTQDSEDDLDWA 1465
W AC D D D A
Sbjct: 1023 W--ACDGDNDCGDFSDEA 1038
Score = 46.2 bits (108), Expect = 3e-04
Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
C D+F C + +CI K +CD DC DE TC+ TC + CG
Sbjct: 886 CPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTAR-TCQVDQFSCG 935
Score = 46.2 bits (108), Expect = 3e-04
Identities = 19/45 (42%), Positives = 23/45 (51%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCD 948
C D +F C N CI K LCD NDC N DE+ C + + D
Sbjct: 886 CPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVD 930
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 12/120 (10%)
Query: 1582 DGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCID 1641
DG+ D D+ P+C + C + F C +C+P G CD +DC D
Sbjct: 2866 DGDFDCPDHSDEAPLNPKCKSA------EQSCNSSFFMC-KNGRCIPSGGLCDNKDDCGD 2918
Query: 1642 GSDEMDCPLSPTPPLCSNMEFPCSTD-ECIPSLLLCDGVPDCHFNEDELICSN-KSCSNG 1699
GSDE +C ++ S CS D + +P C P +D C + CS+G
Sbjct: 2919 GSDERNCHIN---ECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSG 2975
Score = 45.8 bits (107), Expect = 4e-04
Identities = 74/320 (23%), Positives = 107/320 (33%), Gaps = 48/320 (15%)
Query: 682 PVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWY 741
P P C F C + G C CD + DC D SDE +C VC + K
Sbjct: 3349 PDDCPEFRCQPGRFQCGT-GLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQ 3407
Query: 742 QPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTA 801
+ IPV+L NG EE+ R D +N+ Y + T
Sbjct: 3408 KCIPVNL----------RCNGQDDCGDEEDER---DCPENSCSPDYFQCKT-------TK 3447
Query: 802 DILTPI-ISLTGPKCT-LVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAE 859
++ + + P C + + T G + K +N W Q E
Sbjct: 3448 HCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDE 3507
Query: 860 VFLGIRSHTQIVFRAKRGISYIGDVAVD-DISFQDCSPLLSPERKCTDHEFMCANKHCIA 918
++ T F G D D D S + E C+ +F C+N CI
Sbjct: 3508 ENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIP 3567
Query: 919 KDKLCDFVNDCADNSDETT------------FICR-----TSSGRCDFEFDLCSWKQE-- 959
CD DC DE + +IC ++S +C+ E+D E
Sbjct: 3568 AKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMD 3627
Query: 960 -----KDEDFDWNLKASSIP 974
K++ F KA IP
Sbjct: 3628 CVTECKEDQFRCKNKAHCIP 3647
Score = 45.8 bits (107), Expect = 4e-04
Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 1130 CHNGK-CYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWC 1168
C N + C + EQ CN +D CGDN+DE+ CG T++ C
Sbjct: 3723 CRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYKARPC 3762
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 12/79 (15%)
Query: 877 GISYIGDVAVDDISFQDCSPLLSPE-RKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
GI GD + +D C L+ + R C EF C+NK CI D CD ++DC D SDE
Sbjct: 3738 GIDECGDNSDED----HCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDE 3793
Query: 936 -------TTFICRTSSGRC 947
T + C + C
Sbjct: 3794 QGCRIAPTEYTCEDNVNPC 3812
Score = 45.4 bits (106), Expect = 5e-04
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Query: 67 QTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCD 117
QT + + C D+F C +G+CI + +CD DC D++DE A+C + TC+
Sbjct: 920 QTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDE-MASC-EFPTCE 968
Score = 45.4 bits (106), Expect = 5e-04
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 3/44 (6%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDED---PATCS 111
+K C EF C + CI CDS+ DCSD SDE+ P TC+
Sbjct: 3473 KKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCT 3516
Score = 45.4 bits (106), Expect = 5e-04
Identities = 20/42 (47%), Positives = 22/42 (52%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL 114
+C ADEF C + C VCD DC D SDE P C K L
Sbjct: 3673 ICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFL 3714
Score = 45.1 bits (105), Expect = 6e-04
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 880 YIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---- 935
++ D A D S +D S R C +F C N CI + LCD +DC D +DE
Sbjct: 903 WLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASC 962
Query: 936 --------TTFICRTSSGRCDFEFDLCSWKQEKDED 963
T F+C+ SGRC W + D+D
Sbjct: 963 EFPTCEPLTQFVCK--SGRCISS----KWHCDSDDD 992
Score = 43.9 bits (102), Expect = 0.001
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
CS ++F C++ +CI+K +CD DC D DE + C +TC + C
Sbjct: 2720 CSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGA-ITCAADMFSC 2768
Score = 43.5 bits (101), Expect = 0.002
Identities = 18/41 (43%), Positives = 20/41 (48%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKH 113
+C A EF C + CI CD DC D SDED C H
Sbjct: 844 ICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNH 884
Score = 43.1 bits (100), Expect = 0.002
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Query: 74 CSADEFPCTSGQ-CIAKESVCDSRQDCSDESDE-DPATCSKHLTCDFESGFC 123
C+AD F C + C+ + +CD +DC D SDE A C+ + TCD + C
Sbjct: 2761 CAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMC 2812
Score = 43.1 bits (100), Expect = 0.002
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 3/65 (4%)
Query: 886 VDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---TTFICRT 942
VDD P PE +C F C C +CD NDC DNSDE T +C +
Sbjct: 3339 VDDCGDGSDEPDDCPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLS 3398
Query: 943 SSGRC 947
+C
Sbjct: 3399 GQFKC 3403
Score = 42.7 bits (99), Expect = 0.003
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 11/74 (14%)
Query: 903 KCTDHEFMCANK-HCIAKDKLCDFVNDCADNSDETTF-----ICRT-----SSGRCDFEF 951
+C + +F C NK HCI LCD ++DC D SDE ICR ++ C F
Sbjct: 3631 ECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNICRADEFLCNNSLCKLHF 3690
Query: 952 DLCSWKQEKDEDFD 965
+C + + ++ D
Sbjct: 3691 WVCDGEDDCGDNSD 3704
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/54 (42%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 897 LLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---TTFICRTSSGRC 947
L R C C N+ CI KLCD NDC DNSDE C T RC
Sbjct: 2545 LYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRC 2598
Score = 42.4 bits (98), Expect = 0.004
Identities = 22/44 (50%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 74 CSADEFPC-TSGQCIAKESVCDSRQDCSDESDE---DPATCSKH 113
CS D F C T+ CI+K VCD DC+D SDE D TC H
Sbjct: 3436 CSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPH 3479
Score = 42.0 bits (97), Expect = 0.005
Identities = 17/39 (43%), Positives = 22/39 (56%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK 112
C ++F C+SG+CI CD DC D SDE C+K
Sbjct: 1006 CFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTK 1044
Score = 42.0 bits (97), Expect = 0.005
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 16/72 (22%)
Query: 69 QSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPF 128
Q++ C + F C SG+CI +CD ++DC D DE CD C W F
Sbjct: 2677 QNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDE--------FHCD---SSCSWNQF 2725
Query: 129 LTE-----DSHW 135
HW
Sbjct: 2726 ACSAQKCISKHW 2737
Score = 42.0 bits (97), Expect = 0.005
Identities = 18/37 (48%), Positives = 20/37 (54%)
Query: 899 SPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
S E+ C FMC N CI LCD +DC D SDE
Sbjct: 2886 SAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE 2922
Score = 42.0 bits (97), Expect = 0.005
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCS-KHLTCDFESGFCGWE 126
T + C DEF C++ +CI + CD DC D SDE + TC+ CG +
Sbjct: 3756 TYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDD 3815
Query: 127 PFLTE 131
+ +
Sbjct: 3816 AYCNQ 3820
Score = 41.6 bits (96), Expect = 0.007
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 13/67 (19%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQC---NFETG---------ICNWEQ 516
F C+ T CI CD VDDCGD +DE + PE +C F+ G IC+ E
Sbjct: 3322 FRCK-TDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQCGTGLCALPAFICDGEN 3380
Query: 517 DAKDDFD 523
D D+ D
Sbjct: 3381 DCGDNSD 3387
Score = 41.6 bits (96), Expect = 0.007
Identities = 20/43 (46%), Positives = 26/43 (60%), Gaps = 5/43 (11%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDC---SDESDEDPA--TCS 111
CS D+F C++GQCI + CD +DC DE +PA TCS
Sbjct: 3553 CSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCS 3595
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 689 NCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKW-YQPIPV 746
+C + F+C++ G CI CD K DC D SDE +C + C +K S C Q +PV
Sbjct: 2890 SCNSSFFMCKN-GRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPV 2947
Score = 40.8 bits (94), Expect = 0.012
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 9/59 (15%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTED 132
C + F C + CI K+ VCD DC D SDE P C + CG E F D
Sbjct: 2805 CDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESP-------QCGYRQ--CGTEEFSCAD 2854
Score = 40.8 bits (94), Expect = 0.012
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
F+C++ +CI S LCD K DC D SDE +C
Sbjct: 2896 FMCKNGRCIPSGGLCDNKDDCGDGSDERNC 2925
Score = 40.0 bits (92), Expect = 0.021
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 14/67 (20%)
Query: 471 CRHTRACIEKLRLCDLVDDCGDRTDEVNC--------------APELQCNFETGICNWEQ 516
C T C+ +CD +DCGD +DE+ C P +C T IC+ ++
Sbjct: 2646 CNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQK 2705
Query: 517 DAKDDFD 523
D +D D
Sbjct: 2706 DCEDGRD 2712
Score = 40.0 bits (92), Expect = 0.021
Identities = 15/40 (37%), Positives = 25/40 (62%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
+ C+ ++F C+ + CI+K +CD +DC D DE+ IC
Sbjct: 2717 DSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSIC 2756
Score = 40.0 bits (92), Expect = 0.021
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 13/70 (18%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC--------APELQCN-----FETGICN 513
D F C++ CI LCD + DC D +DE NC A E CN +C+
Sbjct: 3635 DQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNICRADEFLCNNSLCKLHFWVCD 3694
Query: 514 WEQDAKDDFD 523
E D D+ D
Sbjct: 3695 GEDDCGDNSD 3704
Score = 40.0 bits (92), Expect = 0.021
Identities = 13/33 (39%), Positives = 24/33 (72%)
Query: 471 CRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL 503
CR+ R C++ ++C+ +D+CGD +DE +C +L
Sbjct: 3723 CRNNRICLQSEQMCNGIDECGDNSDEDHCGGKL 3755
Score = 39.7 bits (91), Expect = 0.027
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 62 VYACGQTQSRKLCSADEFPCTSG-QCIAKESVCDSRQDCSDESDEDPATCSKHL 114
V G + ++LC EF C C+++ +CD DC D+SDE TC + +
Sbjct: 20 VLTVGADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEV 73
Score = 39.7 bits (91), Expect = 0.027
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 3/50 (6%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVN---CAPELQCNFETGICN 513
D F C+ +RAC+ + LCD DC D +DE++ CAP C+ +C+
Sbjct: 2764 DMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCH 2813
Score = 39.7 bits (91), Expect = 0.027
Identities = 14/32 (43%), Positives = 21/32 (65%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C++ F C +G+CI +CD++ DC D SDE
Sbjct: 2891 CNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE 2922
Score = 38.9 bits (89), Expect = 0.046
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 12/84 (14%)
Query: 447 DDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCN 506
D++ C P +C+ + F C H + CI K +CD DDCGD +DE QC
Sbjct: 2792 DELSTAGCA---PNNTCDE-NAFMC-HNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCG 2846
Query: 507 FETGIC-------NWEQDAKDDFD 523
E C N + DFD
Sbjct: 2847 TEEFSCADGRCLLNTQWQCDGDFD 2870
Score = 38.5 bits (88), Expect = 0.060
Identities = 16/31 (51%), Positives = 18/31 (58%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
+F C +KKCI L CD DC D SDE C
Sbjct: 3766 EFACSNKKCIPMDLQCDRLDDCGDGSDEQGC 3796
Score = 38.1 bits (87), Expect = 0.079
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 9/73 (12%)
Query: 74 CSA-DEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTED 132
C+A EF C +G+CI + CD C D+SDE K L C+ S G++P
Sbjct: 2510 CNAYSEFECGNGECIDYQLTCDGIPHCKDKSDE------KLLYCENRSCRRGFKPCYNRR 2563
Query: 133 --SHWKLMKGLNN 143
H KL G N+
Sbjct: 2564 CIPHGKLCDGEND 2576
Score = 38.1 bits (87), Expect = 0.079
Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 12/58 (20%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQ 958
+ KC ++ F C + CI +CD DC D DE F C +S CSW Q
Sbjct: 2679 KHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDE--FHCDSS----------CSWNQ 2724
Score = 38.1 bits (87), Expect = 0.079
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 902 RKCTDHEFMCANKHCIAKDKL-CDFVNDCADNSDETTF--ICRTSSGRCDFEFDLC 954
R+C EF CA+ C+ + CD DC D+SDE C+++ C+ F +C
Sbjct: 2843 RQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFMC 2898
Score = 37.7 bits (86), Expect = 0.10
Identities = 13/35 (37%), Positives = 23/35 (65%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C G++ C+N +C + C+ ++CGDN+DE +C
Sbjct: 2552 CRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 2586
Score = 37.7 bits (86), Expect = 0.10
Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 690 CTDNEFICRSDGHCIEKMQ-KCDFKYDCPDKSDEA 723
C EF C +DG C+ Q +CD +DCPD SDEA
Sbjct: 2845 CGTEEFSC-ADGRCLLNTQWQCDGDFDCPDHSDEA 2878
Score = 37.7 bits (86), Expect = 0.10
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
C EF+C N C +CD +DC DNSDE +C
Sbjct: 3674 CRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMC 3710
Score = 37.4 bits (85), Expect = 0.13
Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLC 738
C EF+C C+ + CD DCPD SDE+ ++ C E C
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDES---LDTCPEEVEIKC 77
Score = 37.4 bits (85), Expect = 0.13
Identities = 15/28 (53%), Positives = 19/28 (67%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDE 105
+F C SG+CI+ + CDS DC D SDE
Sbjct: 972 QFVCKSGRCISSKWHCDSDDDCGDGSDE 999
Score = 37.4 bits (85), Expect = 0.13
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 74 CSADEFPC-TSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGW 125
C+ +EF C G C+ CD +DC D SDE + L CD ++ F W
Sbjct: 1053 CNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRL-CDHKTKFSCW 1104
Score = 37.4 bits (85), Expect = 0.13
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
C EF C +DG CI + +C+ DC D SDE +C C+
Sbjct: 2591 CATVEFRC-ADGTCIPRSARCNQNIDCADASDEKNCNNTDCT 2631
Score = 37.4 bits (85), Expect = 0.13
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C+ EF C G CI + + C+ DC+D SDE
Sbjct: 2591 CATVEFRCADGTCIPRSARCNQNIDCADASDE 2622
Score = 37.4 bits (85), Expect = 0.13
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSG 1446
F+C +K CI +CD+ DC D SDE+ Y G+ F + G
Sbjct: 2810 FMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQ-CGTEEFSCADG 2855
Score = 37.4 bits (85), Expect = 0.13
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 65 CGQTQSRKLCSADEFPCTSGQCIAKES-VCDSRQDCSDESDEDP 107
CG Q C +EF C G+C+ CD DC D SDE P
Sbjct: 2840 CGYRQ----CGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAP 2879
Score = 37.4 bits (85), Expect = 0.13
Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 461 ESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
+SC F C++ R CI LCD DDCGD +DE NC
Sbjct: 2889 QSCNS-SFFMCKNGR-CIPSGGLCDNKDDCGDGSDERNC 2925
Score = 37.4 bits (85), Expect = 0.13
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDED--PATCSK 112
C+ +F C +G C++ CD DC+D SDE +CSK
Sbjct: 3515 CTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCSK 3555
Score = 37.0 bits (84), Expect = 0.18
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
Query: 1108 DSVQEELAVPLPTGFC-PLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSC 1161
D E + PT C PL C +G+C + C+ D+CGD +DE C SC
Sbjct: 954 DQTDEMASCEFPT--CEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSC 1006
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/55 (41%), Positives = 28/55 (50%), Gaps = 12/55 (21%)
Query: 72 KLCS-ADEFPCTS-GQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+LC +F C S G+CI K VCD DC D+SDED D +S CG
Sbjct: 1093 RLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDED----------DCDSFLCG 1137
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 678 ETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA-SCVMEVCSFEKRS 736
E S P + C +N F+C + CI K CD DC D SDE+ C C E+ S
Sbjct: 2793 ELSTAGCAPNNTCDENAFMCHNKV-CIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEEFS 2851
Score = 37.0 bits (84), Expect = 0.18
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL 114
C F C +G C +CD DC D SDE C H+
Sbjct: 3357 CQPGRFQCGTGLCALPAFICDGENDCGDNSDE--LNCDTHV 3395
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLT 1455
++ F C + +CI LCD + DC D++DE + + F SG ++
Sbjct: 928 QVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISS-KWH 986
Query: 1456 QDSEDD 1461
DS+DD
Sbjct: 987 CDSDDD 992
Score = 36.6 bits (83), Expect = 0.23
Identities = 17/43 (39%), Positives = 19/43 (44%)
Query: 908 EFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE 950
EF C N CI CD + C D SDE C S R F+
Sbjct: 2515 EFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFK 2557
Score = 36.6 bits (83), Expect = 0.23
Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 10/55 (18%)
Query: 688 HNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQ 742
H C +N F C S G CI CD + DC D DE C S C W Q
Sbjct: 2680 HKCEENYFSCPS-GRCILNTWICDGQKDCEDGRDEFHC---------DSSCSWNQ 2724
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 9/73 (12%)
Query: 74 CSADEFPCTS-GQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTED 132
C D+F C + CI +CD DC D SDE+ C+ C + FL +
Sbjct: 3632 CKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEE--------NCERGGNICRADEFLCNN 3683
Query: 133 SHWKLMKGLNNGE 145
S KL + +GE
Sbjct: 3684 SLCKLHFWVCDGE 3696
Score = 36.6 bits (83), Expect = 0.23
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 1393 LCPEITDFLCRDKK-CIASHLLCDYKPDCSDRSDEAHC 1429
LCP CR+ + C+ S +C+ +C D SDE HC
Sbjct: 3714 LCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHC 3751
Score = 36.2 bits (82), Expect = 0.30
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 1112 EELAVPLPTGF-CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGW 1170
+EL P+ C Y C +G+C C+ +C D DE C SSC++ + C
Sbjct: 2670 DELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCDSSCSWNQFACSA 2729
Query: 1171 Q 1171
Q
Sbjct: 2730 Q 2730
Score = 36.2 bits (82), Expect = 0.30
Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 25/97 (25%)
Query: 461 ESCE-GLDHFWCRHT----------RACIEKLRLCDLVDDCGDRTDE-------VNCAPE 502
+ CE G D F C + + CI K +CD DDCGD DE + CA +
Sbjct: 2705 KDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAAD 2764
Query: 503 L-------QCNFETGICNWEQDAKDDFDWTRSQGPTP 532
+ C +C+ E+D D D + G P
Sbjct: 2765 MFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAP 2801
Score = 35.8 bits (81), Expect = 0.39
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
Query: 1386 SVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFET-S 1444
SV + CP+ F C++ +CI LCD DC DE ++ T T +C + S
Sbjct: 878 SVNCFNHSCPD-DQFKCQNNRCIPKRWLCDGANDCGSNEDE---SNQTCTARTCQVDQFS 933
Query: 1445 SGN 1447
GN
Sbjct: 934 CGN 936
Score = 35.8 bits (81), Expect = 0.39
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 11/62 (17%)
Query: 473 HTRACIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI-----CNWEQDAKDD 521
+ R CI +LCD +DCGD +DE++C E +C T I CN D D
Sbjct: 2560 YNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADA 2619
Query: 522 FD 523
D
Sbjct: 2620 SD 2621
Score = 35.4 bits (80), Expect = 0.51
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Query: 1378 PNRRSALLSVGEISELCPEITDFLCRDK-KCIASHLLCDYKPDCSDRSDEA 1427
P R + +LC + +FLC D C++ LCD PDC D SDE+
Sbjct: 16 PIARVLTVGADRDQQLC-DPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDES 65
Score = 35.4 bits (80), Expect = 0.51
Identities = 17/34 (50%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 689 NCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE 722
NCT ++F C++D CI KCD DC D SDE
Sbjct: 3316 NCTASQFRCKTD-KCIPFWWKCDTVDDCGDGSDE 3348
Score = 35.4 bits (80), Expect = 0.51
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
CS+ E+ C S CI+ C+ DC+D SDE
Sbjct: 3594 CSSREYICASDGCISASLKCNGEYDCADGSDE 3625
Score = 35.4 bits (80), Expect = 0.51
Identities = 12/28 (42%), Positives = 18/28 (64%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C N KC ++ C+ +D+CGD +DE C
Sbjct: 3769 CSNKKCIPMDLQCDRLDDCGDGSDEQGC 3796
Score = 35.0 bits (79), Expect = 0.67
Identities = 15/39 (38%), Positives = 19/39 (48%)
Query: 80 PCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDF 118
PC + +CI +CD DC D SDE S T +F
Sbjct: 2558 PCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEF 2596
Score = 35.0 bits (79), Expect = 0.67
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----TTFICRTSSGRC 947
CT +F C CI CD V+DC D SDE F C+ +C
Sbjct: 3317 CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQC 3364
Score = 34.7 bits (78), Expect = 0.87
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEAS 724
C + F C+ C+ + CD + DCPD SDE S
Sbjct: 2761 CAADMFSCQGSRACVPRHWLCDGERDCPDGSDELS 2795
Score = 34.7 bits (78), Expect = 0.87
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATC 110
C+A +F C + +CI CD+ DC D SDE P C
Sbjct: 3317 CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE-PDDC 3352
Score = 34.7 bits (78), Expect = 0.87
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 1120 TGFCPLGYREC-HNGKCYRLEQSCNFVDNCGDNTDENEC-GSSCT 1162
T C G +C N KC + CN D+CGD DE +C +SC+
Sbjct: 3393 THVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCS 3437
Score = 34.3 bits (77), Expect = 1.1
Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 14/70 (20%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVN--CAPEL-----------QCNFETGICN 513
D F C++ R CI K LCD +DCG DE N C +C +C+
Sbjct: 889 DQFKCQNNR-CIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCD 947
Query: 514 WEQDAKDDFD 523
E D D D
Sbjct: 948 REDDCGDQTD 957
Score = 34.3 bits (77), Expect = 1.1
Identities = 13/35 (37%), Positives = 18/35 (51%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C + C NG+C C+ D+CGD +DE C
Sbjct: 2891 CNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNC 2925
Score = 34.3 bits (77), Expect = 1.1
Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 6/72 (8%)
Query: 1394 CPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWT 1449
CPE F C C +CD + DC D SDE +C + +G F+ +
Sbjct: 3352 CPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSG--QFKCTKNQKC 3409
Query: 1450 TACSLTQDSEDD 1461
+L + +DD
Sbjct: 3410 IPVNLRCNGQDD 3421
Score = 33.9 bits (76), Expect = 1.5
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTF 1163
C + C NG+C C+ D+CGD TDE +SC F
Sbjct: 927 CQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEM---ASCEF 964
Score = 33.9 bits (76), Expect = 1.5
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
Query: 73 LCSADEFPCTSGQ--CIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
LC + PC + C+ E +C+ ++DC D SDE C + C +G C
Sbjct: 1135 LCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEG-YLCDE---CSLNNGGC 1183
Score = 33.9 bits (76), Expect = 1.5
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 1119 PTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN-ECG-SSCTFEKGWC 1168
P C CHN C + C+ D+CGD +DE+ +CG C E+ C
Sbjct: 2801 PNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEEFSC 2852
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/71 (28%), Positives = 26/71 (36%), Gaps = 14/71 (19%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN-------------ECGSS-CTFEKGWC 1168
C C KC C+ VD+CGD +DE +CG+ C C
Sbjct: 3317 CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQCGTGLCALPAFIC 3376
Query: 1169 GWQNSQADNFD 1179
+N DN D
Sbjct: 3377 DGENDCGDNSD 3387
Score = 33.5 bits (75), Expect = 1.9
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 901 ERKCTDHEFMCANK-HCIAKDKLCDFVNDCADNSDETTFIC 940
++ C EF+C + C+++ LCD DC D+SDE+ C
Sbjct: 29 QQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTC 69
Score = 33.5 bits (75), Expect = 1.9
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C EF CA+ CI + C+ DCAD SDE
Sbjct: 2591 CATVEFRCADGTCIPRSARCNQNIDCADASDE 2622
Score = 33.5 bits (75), Expect = 1.9
Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 73 LCSADEFPCTSGQ-CIAKESVCDSRQDCSDESDE 105
+C + +F CT Q CI C+ + DC DE DE
Sbjct: 3395 VCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDE 3428
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC--AP-ELQCNFETGIC 512
D F C + + CI CD +DDCGD +DE C AP E C C
Sbjct: 3765 DEFACSNKK-CIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPC 3812
Score = 33.1 bits (74), Expect = 2.5
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCN 506
F C + CI C+ DDCGD DE +C PE C+
Sbjct: 3401 FKCTKNQKCIPVNLRCNGQDDCGDEEDERDC-PENSCS 3437
Score = 33.1 bits (74), Expect = 2.5
Identities = 13/29 (44%), Positives = 17/29 (58%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEA 1427
+FLC + C +CD + DC D SDEA
Sbjct: 3678 EFLCNNSLCKLHFWVCDGEDDCGDNSDEA 3706
Score = 32.7 bits (73), Expect = 3.3
Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 904 CTDHEFMC-ANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLC 954
C F C ++ C+ + LCD DC D SDE + + CD +C
Sbjct: 2761 CAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMC 2812
Score = 32.7 bits (73), Expect = 3.3
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 2/58 (3%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDW 1180
C L C NG C C+ +C D +DE C +SC+ ++ C N Q W
Sbjct: 3515 CTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCSKDQFRC--SNGQCIPAKW 3570
Score = 32.7 bits (73), Expect = 3.3
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 438 GIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEV 497
GI+D V D+ ENC C D F C ++ C +CD DDCGD +DE
Sbjct: 3654 GIHDCVDGSDE---ENCERG--GNICRA-DEFLCNNS-LCKLHFWVCDGEDDCGDNSDE- 3705
Query: 498 NCAPELQCNF 507
AP++ F
Sbjct: 3706 --APDMCVKF 3713
Score = 32.3 bits (72), Expect = 4.3
Identities = 16/64 (25%), Positives = 22/64 (34%), Gaps = 13/64 (20%)
Query: 1129 ECHNGKCYRLEQSCNFVDNCGDNTDENEC-------------GSSCTFEKGWCGWQNSQA 1175
+C N C C+ ++C DN+DE C C + WC A
Sbjct: 3482 QCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCA 3541
Query: 1176 DNFD 1179
D D
Sbjct: 3542 DGSD 3545
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 683 VTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
+T C +EF C S+ CI +CD DC D SDE C
Sbjct: 3755 LTYKARPCKKDEFAC-SNKKCIPMDLQCDRLDDCGDGSDEQGC 3796
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/61 (32%), Positives = 27/61 (44%)
Query: 455 TLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNW 514
T P E L+H C T C+ +LC+ V DC D DE EL N + C +
Sbjct: 68 TCPEEVEIKCPLNHIACLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQY 127
Query: 515 E 515
+
Sbjct: 128 K 128
Score = 32.0 bits (71), Expect = 5.6
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 1393 LCPEITDFLCRDK-KCIASHLLCDYKPDCSDRSDEAHC 1429
LC T F C +CI +CD DC D+SDE C
Sbjct: 1094 LCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDC 1131
Score = 31.6 bits (70), Expect = 7.4
Identities = 15/51 (29%), Positives = 22/51 (43%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKW 740
C N C C+ Q C+ DCPD DE E+ S ++ C++
Sbjct: 77 CPLNHIACLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQY 127
Score = 31.6 bits (70), Expect = 7.4
Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 3/50 (6%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENE---CGSSCTFEKGWCG 1169
CP +C N +C C+ ++CG N DE+ +C ++ CG
Sbjct: 886 CPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCG 935
Score = 31.6 bits (70), Expect = 7.4
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 5/47 (10%)
Query: 1389 EISELCPEITD----FLCRDKK-CIASHLLCDYKPDCSDRSDEAHCA 1430
E +C IT F C+ + C+ H LCD + DC D SDE A
Sbjct: 2751 ESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTA 2797
Score = 31.2 bits (69), Expect = 9.6
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 6/48 (12%)
Query: 1108 DSVQEELAVPLPTGFCPLGYREC-HNGKCYRLEQSCNFVDNCGDNTDE 1154
D+ EE+ + CPL + C KC L Q CN V +C D DE
Sbjct: 67 DTCPEEVEIK-----CPLNHIACLGTNKCVHLSQLCNGVLDCPDGYDE 109
Score = 31.2 bits (69), Expect = 9.6
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 703 CIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
CI + CD + DC D SDE C + C+
Sbjct: 2564 CIPHGKLCDGENDCGDNSDELDCKVSTCA 2592
Score = 31.2 bits (69), Expect = 9.6
Identities = 12/26 (46%), Positives = 16/26 (61%)
Query: 474 TRACIEKLRLCDLVDDCGDRTDEVNC 499
T C +CD +DCGD +DE+NC
Sbjct: 3366 TGLCALPAFICDGENDCGDNSDELNC 3391
>gi|4507157 sortilin-related receptor containing LDLR class A repeats
preproprotein [Homo sapiens]
Length = 2214
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/142 (38%), Positives = 70/142 (49%), Gaps = 15/142 (10%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPL------SPTPP---LCSNM 1660
PS C + + C + CV + CDG+ DC DGSDE CPL + TP C
Sbjct: 1416 PSTCLPNYYRCS-SGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRF 1474
Query: 1661 EFPCSTDE-CIPSLLLCDGVPDCHFNEDELIC---SNKSCSNGALVCASSNSCIPAHQRC 1716
EF C + CIP+ CDG DC DE C S +C + C +CI +RC
Sbjct: 1475 EFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERC 1534
Query: 1717 DGFADCMDFQLDESSCSDTWTL 1738
DGF DC D + DE +CSD T+
Sbjct: 1535 DGFLDCSD-ESDEKACSDELTV 1555
Score = 80.1 bits (196), Expect = 2e-14
Identities = 48/122 (39%), Positives = 57/122 (46%), Gaps = 22/122 (18%)
Query: 1613 CEAD-QFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C+ D QF C + C+PLS KCD +DC D SDE C + C + E+ CS+ CI
Sbjct: 1117 CDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQ----CRSDEYNCSSGMCIR 1172
Query: 1672 SLLLCDGVPDCHFNEDELIC---------SNKSCSNGALVCASSNSCIPAHQRCDGFADC 1722
S +CDG DC DE C SN C NG CIP CDG DC
Sbjct: 1173 SSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNG--------HCIPQRWACDGDTDC 1224
Query: 1723 MD 1724
D
Sbjct: 1225 QD 1226
Score = 74.7 bits (182), Expect = 8e-13
Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
Query: 1601 VTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNM 1660
VT P Q C+ +F C C+P +CDGH+DC DG DE +CP T C +
Sbjct: 1459 VTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHST-LTCMSR 1517
Query: 1661 EFPCSTDE-CIPSLLLCDGVPDCHFNEDELICSNK 1694
EF C E CI CDG DC DE CS++
Sbjct: 1518 EFQCEDGEACIVLSERCDGFLDCSDESDEKACSDE 1552
Score = 70.1 bits (170), Expect = 2e-11
Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 13/131 (9%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSN-MEFPCSTDECIP 1671
C+ F C + C+ L KCDG +DC D SDE +C P CS +F C CIP
Sbjct: 1325 CDEFGFQCQNGV-CISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIP 1383
Query: 1672 SLLLCDGVPDCHFNEDELICSNKS----CSNGALVC------ASSNSCIPAHQRCDGFAD 1721
+ CD DC DE C + + G C SS +C+ CDG+ D
Sbjct: 1384 NRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRD 1443
Query: 1722 CMDFQLDESSC 1732
C D DE +C
Sbjct: 1444 CADGS-DEEAC 1453
Score = 68.9 bits (167), Expect = 4e-11
Identities = 41/114 (35%), Positives = 45/114 (39%), Gaps = 10/114 (8%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNM--EFPCSTDECI 1670
CEA F C C+P CDG DC DGSDE P C F C CI
Sbjct: 1199 CEASNFQC-RNGHCIPQRWACDGDTDCQDGSDE-------DPVNCEKKCNGFRCPNGTCI 1250
Query: 1671 PSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
PS CDG+ DC DE C VC + C+ CDG C D
Sbjct: 1251 PSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRD 1304
Score = 68.6 bits (166), Expect = 5e-11
Identities = 45/130 (34%), Positives = 54/130 (41%), Gaps = 10/130 (7%)
Query: 1618 FSCIYTLQCVPLSGKCDGHEDCIDGSDE----MDCPLSPT-PPLCSNMEFPCSTDECIPS 1672
F C QC+ S CDG C DGSDE C P +C F C CI
Sbjct: 1281 FVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISL 1340
Query: 1673 LLLCDGVPDCHFNEDELICSN----KSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLD 1728
+ CDG+ DC DE C N +CS + CIP +CD DC D+ D
Sbjct: 1341 IWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWS-D 1399
Query: 1729 ESSCSDTWTL 1738
E C D+ L
Sbjct: 1400 EKDCGDSHIL 1409
Score = 65.5 bits (158), Expect = 5e-10
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 1609 QPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCS-NMEFPC-ST 1666
+ + C +Q+ C C+ CD DC D SDE +CP + +C + +F C +
Sbjct: 1074 EENTCLRNQYRCSNG-NCINSIWWCDFDNDCGDMSDERNCPTT----ICDLDTQFRCQES 1128
Query: 1667 DECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQ 1726
CIP CD DC N DE C C + C SS CI + CDG DC D+
Sbjct: 1129 GTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNC-SSGMCIRSSWVCDGDNDCRDWS 1187
Query: 1727 LDESSCS 1733
DE++C+
Sbjct: 1188 -DEANCT 1193
Score = 51.2 bits (121), Expect = 9e-06
Identities = 65/284 (22%), Positives = 105/284 (36%), Gaps = 44/284 (15%)
Query: 667 GNLPADLPTPPETSVPVTLPPHN-CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
G+L D P + + N C N++ C S+G+CI + CDF DC D SDE +C
Sbjct: 1054 GDLMCDCPQGYQLKNNTCVKEENTCLRNQYRC-SNGNCINSIWWCDFDNDCGDMSDERNC 1112
Query: 726 VMEVCSFEKRSLCKWYQP-IPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNT-- 782
+C + + C+ IP+ D G+ H E + S ++ ++
Sbjct: 1113 PTTICDLDTQFRCQESGTCIPLSYKCDLED---DCGDNSDESHCEMHQCRSDEYNCSSGM 1169
Query: 783 --TDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNV 840
W D+ + D A+ CT ++ T + Q + +
Sbjct: 1170 CIRSSWVCDGDNDCRDWSDEAN------------CTAIYHT----CEASNFQ--CRNGHC 1211
Query: 841 TSKLWAQTGQQGAQWKRAEVFL-------GIRSHTQIVFRAKRGISYIGDVAVDDISFQD 893
+ WA G Q E + G R + + + D + D Q
Sbjct: 1212 IPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLRDCS-DGSDEQH 1270
Query: 894 CSPLLSPERKCTDH-EFMCANK-HCIAKDKLCDFVNDCADNSDE 935
C PL CT +F+C N+ C+ +CD + C D SDE
Sbjct: 1271 CEPL------CTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDE 1308
Score = 49.3 bits (116), Expect = 3e-05
Identities = 19/39 (48%), Positives = 21/39 (53%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK 112
C A F C +G CI + CD DC D SDEDP C K
Sbjct: 1199 CEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEK 1237
Score = 47.0 bits (110), Expect = 2e-04
Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
C +DE+ C+SG CI VCD DC D SDE T H TC+ + C
Sbjct: 1158 CRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYH-TCEASNFQC 1206
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/283 (24%), Positives = 96/283 (33%), Gaps = 76/283 (26%)
Query: 1389 EISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSC---NFETSS 1445
E ++C E F C++ CI+ CD DC D SDEA+C + T F +
Sbjct: 1320 EFHKVCDEF-GFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCEN 1378
Query: 1446 GNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGS-------- 1497
G+ D DW+ ++P S P + Y SSG+
Sbjct: 1379 GHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVC 1438
Query: 1498 ------KEGS------VARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGL 1545
+GS + T+ S P LG C RF F P++
Sbjct: 1439 DGYRDCADGSDEEACPLLANVTAASTPTQLGRCD-RFEFECHQPKTC------------- 1484
Query: 1546 NILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGP 1605
I W KR DG++D D+ + C T
Sbjct: 1485 -IPNW-----KR-----------------------CDGHQDCQDGRDEAN----CPTHST 1511
Query: 1606 VPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDC 1648
+ C + +F C C+ LS +CDG DC D SDE C
Sbjct: 1512 L-----TCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKAC 1549
Score = 46.2 bits (108), Expect = 3e-04
Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 15/99 (15%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGN-----WTTACS 1453
++ C CI S +CD DC D SDEA+C T + NF+ +G+ W AC
Sbjct: 1162 EYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNGHCIPQRW--ACD 1219
Query: 1454 LTQDSEDDLD--------WAIGSRIPAKALIPDSDHTPG 1484
D +D D G R P IP S H G
Sbjct: 1220 GDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDG 1258
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQC-----NFETGIC- 512
P C+ F C+ + CI CDL DDCGD +DE +C QC N +G+C
Sbjct: 1113 PTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMH-QCRSDEYNCSSGMCI 1171
Query: 513 --NWEQDAKDDF-DWTRSQGPTPTLNT 536
+W D +D DW+ T +T
Sbjct: 1172 RSSWVCDGDNDCRDWSDEANCTAIYHT 1198
Score = 45.8 bits (107), Expect = 4e-04
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 20/105 (19%)
Query: 877 GISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDET 936
GI D + +D +F CS + C + F C N CI+ CD ++DC D SDE
Sbjct: 1298 GIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEA 1357
Query: 937 T-------------FICRTSSG-------RCDFEFDLCSWKQEKD 961
F R +G +CD E D W EKD
Sbjct: 1358 NCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKD 1402
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 17/69 (24%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE-----------TTFICRTS------ 943
E C +++ C+N +CI CDF NDC D SDE T F C+ S
Sbjct: 1075 ENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPL 1134
Query: 944 SGRCDFEFD 952
S +CD E D
Sbjct: 1135 SYKCDLEDD 1143
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/49 (46%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 68 TQSRKLCSADEFPCTSGQ-CIAKESVCDSRQDCSDESDEDPATCSKHLT 115
T S C + EF C G+ CI CD DCSDESDE CS LT
Sbjct: 1508 THSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDE--KACSDELT 1554
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 1393 LCPEITDFLCRDK-KCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTA 1451
+C T F C++ CI CD + DC D SDE+HC + S + SSG +
Sbjct: 1116 ICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCR--SDEYNCSSGMCIRS 1173
Query: 1452 CSLTQDSEDDLDWA 1465
+ D DW+
Sbjct: 1174 SWVCDGDNDCRDWS 1187
Score = 40.0 bits (92), Expect = 0.021
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 8/67 (11%)
Query: 65 CGQT-QSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE-------DPATCSKHLTC 116
C Q + K+C F C +G CI+ CD DC D SDE + CS++
Sbjct: 1315 CSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQF 1374
Query: 117 DFESGFC 123
E+G C
Sbjct: 1375 RCENGHC 1381
Score = 40.0 bits (92), Expect = 0.021
Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
Query: 686 PPHN---CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSL 737
P H+ C EF C CI ++CD DC D+SDE +C E+ ++ ++L
Sbjct: 1507 PTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNL 1561
Score = 39.3 bits (90), Expect = 0.035
Identities = 36/114 (31%), Positives = 48/114 (42%), Gaps = 15/114 (13%)
Query: 893 DCSPLLSPERKCT------DHEFMCANKH-CIAKDKLCDFVNDCADNSDET---TFICRT 942
DC + S ER C D +F C CI CD +DC DNSDE+ CR+
Sbjct: 1102 DCGDM-SDERNCPTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRS 1160
Query: 943 SSGRCDFEFDL-CSWKQEKDEDF-DWNLKASSIPAAGTEPAADHTLGNSSGHYI 994
C + SW + D D DW+ +A+ T A++ N GH I
Sbjct: 1161 DEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRN--GHCI 1212
Score = 38.9 bits (89), Expect = 0.046
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 16/83 (19%)
Query: 882 GDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE------ 935
GD D S +D ++ E+KC F C N CI K CD + DC+D SDE
Sbjct: 1220 GDTDCQDGSDEDP---VNCEKKCNG--FRCPNGTCIPSSKHCDGLRDCSDGSDEQHCEPL 1274
Query: 936 ----TTFICRTSSGRCDFEFDLC 954
F+C+ +C F +C
Sbjct: 1275 CTHFMDFVCKNRQ-QCLFHSMVC 1296
Score = 38.9 bits (89), Expect = 0.046
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 14/70 (20%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNC-----APE----LQCNFETGIC---NWEQ 516
F C++ CI + CD +DDCGD +DE NC AP Q E G C W+
Sbjct: 1330 FQCQNG-VCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIPNRWKC 1388
Query: 517 DAKDDF-DWT 525
D ++D DW+
Sbjct: 1389 DRENDCGDWS 1398
Score = 38.5 bits (88), Expect = 0.060
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 1119 PTGFCPLG--YRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
PT C L +R +G C L C+ D+CGDN+DE+ C
Sbjct: 1113 PTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHC 1153
Score = 38.5 bits (88), Expect = 0.060
Identities = 16/48 (33%), Positives = 25/48 (52%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT 115
T C + + C+SG C+ VCD +DC+D SDE+ ++T
Sbjct: 1413 TPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVT 1460
Score = 38.1 bits (87), Expect = 0.079
Identities = 24/70 (34%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 441 DGVSAIDDIRFE-NCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
DG+ D E NC P A +C F C + CI CD +DCGD +DE +C
Sbjct: 1345 DGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGH-CIPNRWKCDRENDCGDWSDEKDC 1403
Query: 500 APELQCNFET 509
F T
Sbjct: 1404 GDSHILPFST 1413
Score = 38.1 bits (87), Expect = 0.079
Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 10/59 (16%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---------TTFICRTSSGRCD-FEFD 952
C + + C++ C+ +CD DCAD SDE T T GRCD FEF+
Sbjct: 1419 CLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFE 1477
Score = 37.4 bits (85), Expect = 0.13
Identities = 16/37 (43%), Positives = 17/37 (45%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
C F C N HCI + CD DC D SDE C
Sbjct: 1199 CEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNC 1235
Score = 36.2 bits (82), Expect = 0.30
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 10/55 (18%)
Query: 79 FPCTSGQCIAKESVCDSRQDCSDESDEDPA----------TCSKHLTCDFESGFC 123
F C +G CI CD +DCSD SDE C C F S C
Sbjct: 1242 FRCPNGTCIPSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVC 1296
Score = 35.8 bits (81), Expect = 0.39
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 11/55 (20%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNCAPELQCNFET-------GIC---NWEQDAKDD 521
CI + CD +DCGD +DE NC P C+ +T G C +++ D +DD
Sbjct: 1090 CINSIWWCDFDNDCGDMSDERNC-PTTICDLDTQFRCQESGTCIPLSYKCDLEDD 1143
Score = 35.8 bits (81), Expect = 0.39
Identities = 70/314 (22%), Positives = 107/314 (34%), Gaps = 44/314 (14%)
Query: 687 PHNCTD--NEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPI 744
P NC N F C +G CI + CD DC D SDE C +C+ +CK Q
Sbjct: 1232 PVNCEKKCNGFRC-PNGTCIPSSKHCDGLRDCSDGSDEQHCE-PLCTHFMDFVCKNRQQC 1289
Query: 745 PVHLLQDSNTFRWGLGNG-----ISIHHGEENHRPSVDHTQNTTDG------WYLYADSS 793
H + + G+ E H+ + +G W
Sbjct: 1290 LFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDD 1349
Query: 794 NGKFGDTADILTPIISLTGPKCTLVFWTHM-NGATVGSLQVLIKKDNVTSKLWAQTGQQG 852
G + D A+ P P C+ F NG + + ++++ W+ G
Sbjct: 1350 CGDYSDEANCENPT---EAPNCSRYFQFRCENGHCIPNRWKCDRENDCGD--WSDEKDCG 1404
Query: 853 AQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVD------DISFQDCSPLLS------- 899
G + +R G + D D S ++ PLL+
Sbjct: 1405 DSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAAST 1464
Query: 900 PER--KCTDHEFMCAN-KHCIAKDKLCDFVNDCADNSDE------TTFICRTSSGRCDFE 950
P + +C EF C K CI K CD DC D DE +T C + +C+ +
Sbjct: 1465 PTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCE-D 1523
Query: 951 FDLCSWKQEKDEDF 964
+ C E+ + F
Sbjct: 1524 GEACIVLSERCDGF 1537
Score = 35.8 bits (81), Expect = 0.39
Identities = 16/30 (53%), Positives = 17/30 (56%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
F C + CI S CD DCSD SDE HC
Sbjct: 1242 FRCPNGTCIPSSKHCDGLRDCSDGSDEQHC 1271
Score = 35.4 bits (80), Expect = 0.51
Identities = 13/29 (44%), Positives = 18/29 (62%)
Query: 1129 ECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
+C NG C L C+ +D+CGD +DE C
Sbjct: 1331 QCQNGVCISLIWKCDGMDDCGDYSDEANC 1359
Score = 34.7 bits (78), Expect = 0.87
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 13/72 (18%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFET-----SSGN---WTTA 1451
+ C + CI S CD+ DC D SDE +C T C+ +T SG +
Sbjct: 1083 YRCSNGNCINSIWWCDFDNDCGDMSDERNC-----PTTICDLDTQFRCQESGTCIPLSYK 1137
Query: 1452 CSLTQDSEDDLD 1463
C L D D+ D
Sbjct: 1138 CDLEDDCGDNSD 1149
Score = 34.7 bits (78), Expect = 0.87
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENECGSS 1160
C NG C C+ ++CGD +DE +CG S
Sbjct: 1376 CENGHCIPNRWKCDRENDCGDWSDEKDCGDS 1406
Score = 34.7 bits (78), Expect = 0.87
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 681 VPVTLP-PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
+P + P P C N + C S G C+ CD DC D SDE +C
Sbjct: 1409 LPFSTPGPSTCLPNYYRC-SSGTCVMDTWVCDGYRDCADGSDEEAC 1453
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGF 122
C +++ C++G CI CD DC D SDE C + CD ++ F
Sbjct: 1078 CLRNQYRCSNGNCINSIWWCDFDNDCGDMSDE--RNCPTTI-CDLDTQF 1123
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 6/50 (12%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSD------EAHCAHYTSTTGSC 1439
E ++F CR+ CI CD DC D SD E C + G+C
Sbjct: 1200 EASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTC 1249
Score = 33.9 bits (76), Expect = 1.5
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 1126 GYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCT 1162
G+R C NG C + C+ + +C D +DE C CT
Sbjct: 1241 GFR-CPNGTCIPSSKHCDGLRDCSDGSDEQHCEPLCT 1276
Score = 33.5 bits (75), Expect = 1.9
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDE 105
+F C +G CI CD DC D SDE
Sbjct: 1373 QFRCENGHCIPNRWKCDRENDCGDWSDE 1400
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/46 (43%), Positives = 21/46 (45%), Gaps = 5/46 (10%)
Query: 74 CSADEFPCTSGQ-CIAKESVCDSRQDCSDESDEDPATCSKH--LTC 116
C EF C + CI CD QDC D DE A C H LTC
Sbjct: 1471 CDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDE--ANCPTHSTLTC 1514
Score = 33.5 bits (75), Expect = 1.9
Identities = 19/57 (33%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWT 525
F C ACI CD DC D +DE C+ EL ++ W D D T
Sbjct: 1519 FQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTV-YKVQNLQWTADFSGDVTLT 1574
Score = 33.1 bits (74), Expect = 2.5
Identities = 13/35 (37%), Positives = 17/35 (48%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C C NG C C+F ++CGD +DE C
Sbjct: 1078 CLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNC 1112
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/31 (41%), Positives = 15/31 (48%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
F C + CI + CD DC D DE NC
Sbjct: 1476 FECHQPKTCIPNWKRCDGHQDCQDGRDEANC 1506
Score = 32.3 bits (72), Expect = 4.3
Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 4/43 (9%)
Query: 73 LCSAD-EFPCT-SGQCIAKESVCDSRQDCSDESDEDPATCSKH 113
+C D +F C SG CI CD DC D SDE + C H
Sbjct: 1116 ICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDE--SHCEMH 1156
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 9/66 (13%)
Query: 904 CTDHEFMCAN-KHCIAKDKLCDFVNDCADNSDE-------TTFICRTSSGRCDFEFDL-C 954
C EF C + + CI + CD DC+D SDE T + + DF D+
Sbjct: 1514 CMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTL 1573
Query: 955 SWKQEK 960
+W + K
Sbjct: 1574 TWMRPK 1579
Score = 31.6 bits (70), Expect = 7.4
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 12/59 (20%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNCAP------------ELQCNFETGICNWEQDAKDDFD 523
CI + CD + DC D +DE +C P QC F + +C+ +D D
Sbjct: 1249 CIPSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSD 1307
Score = 31.6 bits (70), Expect = 7.4
Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 1393 LCPEITDFLCRDKK-CIASHLLCDYKPDCSDRSDE 1426
LC DF+C++++ C+ ++CD C D SDE
Sbjct: 1274 LCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDE 1308
Score = 31.6 bits (70), Expect = 7.4
Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 8/52 (15%)
Query: 78 EFPCTSGQ-CIAKESVCDSRQDCSDESDEDP--ATCSK----HLTCDFESGF 122
+F C + Q C+ VCD C D SDED A CS+ H CD E GF
Sbjct: 1280 DFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCD-EFGF 1330
Score = 31.2 bits (69), Expect = 9.6
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 1399 DFLCRD-KKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQD 1457
+F C D + CI CD DCSD SDE C+ + ++ + WT S
Sbjct: 1518 EFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTV-----YKVQNLQWTADFS---- 1568
Query: 1458 SEDDLDWAIGSRIPAKALI 1476
+ L W ++P+ + +
Sbjct: 1569 GDVTLTWMRPKKMPSASCV 1587
>gi|119709832 low density lipoprotein receptor-related protein 5 [Homo
sapiens]
Length = 1615
Score = 92.4 bits (228), Expect = 4e-18
Identities = 49/128 (38%), Positives = 65/128 (50%), Gaps = 10/128 (7%)
Query: 1609 QPSPCEADQFSCIY-TLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTD 1667
+P C DQF+C + C+P + +CDG +C D SDE CP+ CS +FPC+
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPV------CSAAQFPCARG 1308
Query: 1668 ECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQL 1727
+C+ L CDG DC DE C + C CA S C+ Q+CD F DC+D
Sbjct: 1309 QCVDLRLRCDGEADCQDRSDEADC-DAICLPNQFRCA-SGQCVLIKQQCDSFPDCIDGS- 1365
Query: 1728 DESSCSDT 1735
DE C T
Sbjct: 1366 DELMCEIT 1373
Score = 44.3 bits (103), Expect = 0.001
Identities = 17/33 (51%), Positives = 20/33 (60%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
+CSA +FPC GQC+ CD DC D SDE
Sbjct: 1297 VCSAAQFPCARGQCVDLRLRCDGEADCQDRSDE 1329
Score = 43.1 bits (100), Expect = 0.002
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTP----PLCSNMEFPCSTDE 1668
C +QF C + QCV + +CD DCIDGSDE+ C ++ P P S+ P
Sbjct: 1336 CLPNQFRCA-SGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSPAHSSAIGP--VIG 1392
Query: 1669 CIPSLLLCDGVPDCHFNEDELICSNKSCSNG 1699
I SL + GV +F ++C + +NG
Sbjct: 1393 IILSLFVMGGV---YFVCQRVVCQRYAGANG 1420
Score = 40.4 bits (93), Expect = 0.016
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
+C ++F C SGQC+ + CDS DC D SDE
Sbjct: 1335 ICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDE 1367
Score = 38.1 bits (87), Expect = 0.079
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 17/87 (19%)
Query: 1392 ELCP--EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC------AHYTSTTGSCNF-- 1441
E CP F C +C+ L CD + DC DRSDEA C + +G C
Sbjct: 1293 EGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQFRCASGQCVLIK 1352
Query: 1442 -------ETSSGNWTTACSLTQDSEDD 1461
+ G+ C +T+ DD
Sbjct: 1353 QQCDSFPDCIDGSDELMCEITKPPSDD 1379
Score = 37.4 bits (85), Expect = 0.13
Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
C+ +F C + G C++ +CD + DC D+SDEA C
Sbjct: 1298 CSAAQFPC-ARGQCVDLRLRCDGEADCQDRSDEADC 1332
Score = 36.2 bits (82), Expect = 0.30
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 5/44 (11%)
Query: 65 CGQTQSRKLCSADEFPCTSGQ--CIAKESVCDSRQDCSDESDED 106
CG+ + CS D+F C +G+ CI CD +C D+SDE+
Sbjct: 1253 CGEPPT---CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEE 1293
Score = 35.4 bits (80), Expect = 0.51
Identities = 16/44 (36%), Positives = 22/44 (50%)
Query: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
QD S + C ++F CA+ C+ + CD DC D SDE
Sbjct: 1324 QDRSDEADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDE 1367
Score = 35.4 bits (80), Expect = 0.51
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
C N+F C S G C+ Q+CD DC D SDE C
Sbjct: 1336 CLPNQFRCAS-GQCVLIKQQCDSFPDCIDGSDELMC 1370
Score = 35.0 bits (79), Expect = 0.67
Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSC-----TFEKGWCGWQNSQADN 1177
C C G+C L C+ +C D +DE +C + C G C Q D+
Sbjct: 1298 CSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQFRCASGQCVLIKQQCDS 1357
Query: 1178 FDWVLGVGSHQSL----RPPKDHTLGNENAI 1204
F + GS + + +PP D + + +AI
Sbjct: 1358 FPDCID-GSDELMCEITKPPSDDSPAHSSAI 1387
Score = 34.7 bits (78), Expect = 0.87
Identities = 34/121 (28%), Positives = 48/121 (39%), Gaps = 16/121 (13%)
Query: 887 DDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDET--TFIC---- 940
DD S ++ P+ C+ +F CA C+ CD DC D SDE IC
Sbjct: 1287 DDQSDEEGCPV------CSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQ 1340
Query: 941 -RTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSL 999
R +SG+C C + + D + + P + PA +G G I SL
Sbjct: 1341 FRCASGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSPAHSSAIGPVIG---IILSL 1397
Query: 1000 F 1000
F
Sbjct: 1398 F 1398
Score = 34.3 bits (77), Expect = 1.1
Identities = 35/154 (22%), Positives = 60/154 (38%), Gaps = 27/154 (17%)
Query: 589 MFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGF 648
+ GK +Y W D + Q++ ++ G++ R ++ + E S+ +
Sbjct: 1162 ILGKHLY--------WIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAVEEVSLEEFS 1213
Query: 649 TGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTL----------PPHNCTDNEFICR 698
A D+ + G+ P S PV L P C+ ++F C
Sbjct: 1214 AHPCARDNGGCSHICIAKGD------GTPRCSCPVHLVLLQNLLTCGEPPTCSPDQFACA 1267
Query: 699 S-DGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
+ + CI +CD +C D+SDE C VCS
Sbjct: 1268 TGEIDCIPGAWRCDGFPECDDQSDEEGC--PVCS 1299
Score = 31.6 bits (70), Expect = 7.4
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Query: 1384 LLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-----AHYTSTTGS 1438
LL+ GE P+ + CI CD P+C D+SDE C A + G
Sbjct: 1250 LLTCGEPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQ 1309
Query: 1439 C 1439
C
Sbjct: 1310 C 1310
>gi|66082554 low density lipoprotein receptor-related protein 8
isoform 2 precursor [Homo sapiens]
Length = 793
Score = 91.7 bits (226), Expect = 6e-18
Identities = 52/137 (37%), Positives = 71/137 (51%), Gaps = 12/137 (8%)
Query: 1603 GGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEF 1662
GG P + CE DQF C +C+P +CD +DC+D SDE DCP C++ +F
Sbjct: 39 GGQGPAKD--CEKDQFQC-RNERCIPSVWRCDEDDDCLDHSDEDDCP----KKTCADSDF 91
Query: 1663 PCSTDECIPSLLLCDGVPDC--HFNEDELICSNKSCSNGALVCA-SSNSCIPAHQRCDGF 1719
C CI CDG +C +E E C+ + C L C +S+ C+PA RCDG
Sbjct: 92 TCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGE 151
Query: 1720 ADCMDFQLDESSCSDTW 1736
DC + DE+ C+ TW
Sbjct: 152 KDC-EGGADEAGCA-TW 166
Score = 53.9 bits (128), Expect = 1e-06
Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSD--EASCVMEVCSFEKRS 736
P C D++F C +GHCI + KCD + +CPD SD EA+C +VC EK S
Sbjct: 82 PKKTCADSDFTC-DNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLS 133
Score = 51.2 bits (121), Expect = 9e-06
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+K C+ +F C +G CI + CD ++C D SDE ATC+K + C E CG
Sbjct: 83 KKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCG 135
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 883 DVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC-- 940
D +D DC P++ C D +F C N HCI + CD +C D SDE+ C
Sbjct: 70 DDCLDHSDEDDC-----PKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTK 124
Query: 941 ------RTSSGRCDFEFDLCSWKQEKDED 963
+ S G + SW+ + ++D
Sbjct: 125 QVCPAEKLSCGPTSHKCVPASWRCDGEKD 153
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-----------QCNF 507
PA+ CE D F CR+ R CI + CD DDC D +DE +C + C
Sbjct: 43 PAKDCEK-DQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIH 100
Query: 508 ETGICNWEQDAKDDFD-----WTRSQGPTPTLNTGP 538
E C+ E++ D D T+ P L+ GP
Sbjct: 101 ERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGP 136
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCS-KHLTCDFESGFC 123
K C D+F C + +CI CD DC D SDED TC+ TCD +G C
Sbjct: 45 KDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCD--NGHC 98
Score = 40.0 bits (92), Expect = 0.021
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
P +C ++F CR++ CI + +CD DC D SDE C + C+
Sbjct: 43 PAKDCEKDQFQCRNE-RCIPSVWRCDEDDDCLDHSDEDDCPKKTCA 87
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Query: 896 PLLS---PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----------TTFICRT 942
PLL P + C +F C N+ CI CD +DC D+SDE + F C
Sbjct: 36 PLLGGQGPAKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-- 93
Query: 943 SSGRCDFEFDLCSWKQEKDEDFD 965
+G C E C ++E + D
Sbjct: 94 DNGHCIHERWKCDGEEECPDGSD 116
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-------AHYTSTTGSCNFE 1442
E F CR+++CI S CD DC D SDE C + +T G C E
Sbjct: 48 EKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHE 101
Score = 33.1 bits (74), Expect = 2.5
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 68 TQSRKLCSADEFPC--TSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFC 123
T ++++C A++ C TS +C+ CD +DC +DE A C+ L C +G C
Sbjct: 121 TCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADE--AGCATWLNECLHNNGGC 177
Score = 31.6 bits (70), Expect = 7.4
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query: 1394 CPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSS 1445
CP+ T DF C + CI CD + +C D SDE+ T T C E S
Sbjct: 81 CPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEA---TCTKQVCPAEKLS 133
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 91.3 bits (225), Expect = 8e-18
Identities = 50/139 (35%), Positives = 66/139 (47%), Gaps = 10/139 (7%)
Query: 1599 ECVTGGPVPVQPSP--CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE--MDCPLSPTP 1654
+CV G P + C D+F C + +C+P KCDG +DC DGSDE +C
Sbjct: 3478 DCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEEC----DE 3533
Query: 1655 PLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQ 1714
C +F C + C+P CD DC N DE C+ + CS CA+ CI
Sbjct: 3534 RTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGR-CIAGRW 3592
Query: 1715 RCDGFADCMDFQLDESSCS 1733
+CDG DC D DE C+
Sbjct: 3593 KCDGDHDCADGS-DEKDCT 3610
Score = 86.3 bits (212), Expect = 3e-16
Identities = 48/131 (36%), Positives = 65/131 (49%), Gaps = 4/131 (3%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPC-STDE 1668
P C D+F C C+PL +CDG DC+D SDE C T +++F C +
Sbjct: 1059 PGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCE-GVTHVCDPSVKFGCKDSAR 1117
Query: 1669 CIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNS-CIPAHQRCDGFADCMDFQL 1727
CI +CDG DC N DE C + +C + CA++ S C+P + CDG DC D
Sbjct: 1118 CISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGS- 1176
Query: 1728 DESSCSDTWTL 1738
DE D +L
Sbjct: 1177 DEGELCDQCSL 1187
Score = 84.7 bits (208), Expect = 7e-16
Identities = 49/125 (39%), Positives = 60/125 (48%), Gaps = 7/125 (5%)
Query: 1611 SPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEM-DCPLSPTPPLCSNMEFPCSTDEC 1669
S C A QF C +C+P KCD +DC D SDE DCP C +F CST C
Sbjct: 3332 SNCTASQFVCKND-KCIPFWWKCDTEDDCGDHSDEPPDCPEFK----CRPGQFQCSTGIC 3386
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDE 1729
+CDG DC N DE C C C ++N CIP RC+G +C D + DE
Sbjct: 3387 TNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGE-DE 3445
Query: 1730 SSCSD 1734
C +
Sbjct: 3446 RDCPE 3450
Score = 82.8 bits (203), Expect = 3e-15
Identities = 40/113 (35%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C + F+C + +C+P+S CD +DC G DE C CS +F C CI
Sbjct: 2696 CPLNYFACP-SGRCIPMSWTCDKEDDCEHGEDETHCN-----KFCSEAQFECQNHRCISK 2749
Query: 1673 LLLCDGVPDCHFNEDELI-CSNKSCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
LCDG DC DE C K+C + C ++ C+P CDG DC D
Sbjct: 2750 QWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCAD 2802
Score = 82.4 bits (202), Expect = 4e-15
Identities = 46/124 (37%), Positives = 61/124 (49%), Gaps = 15/124 (12%)
Query: 1617 QFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLC 1676
QF+C +C+ ++ +CD DC D SDE C S CS+ +F C++ CIP C
Sbjct: 981 QFTC-NNGRCININWRCDNDNDCGDNSDEAGCSHS-----CSSTQFKCNSGRCIPEHWTC 1034
Query: 1677 DGVPDC--HFNEDELICSNKS------CSNGALVCASSNSCIPAHQRCDGFADCMDFQLD 1728
DG DC + +E C+N++ C C CIP RCDG DCMD D
Sbjct: 1035 DGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMD-SSD 1093
Query: 1729 ESSC 1732
E SC
Sbjct: 1094 EKSC 1097
Score = 79.0 bits (193), Expect = 4e-14
Identities = 50/124 (40%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE-MDCPLSPTPPLCSNMEFPCSTDECIP 1671
C +QFSC + +C+P+S CD +DC D SDE C PL +F C+ CI
Sbjct: 936 CPPNQFSCA-SGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPL---TQFTCNNGRCIN 991
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
CD DC N DE CS+ SCS+ C +S CIP H CDG DC D+ DE+
Sbjct: 992 INWRCDNDNDCGDNSDEAGCSH-SCSSTQFKC-NSGRCIPEHWTCDGDNDCGDYS-DETH 1048
Query: 1732 CSDT 1735
+ T
Sbjct: 1049 ANCT 1052
Score = 77.8 bits (190), Expect = 9e-14
Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 19/164 (11%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCS-TDECIP 1671
C QF C + C + CDG DC D SDE +C + +C +F C+ T+ CIP
Sbjct: 3374 CRPGQFQCSTGI-CTNPAFICDGDNDCQDNSDEANCDIH----VCLPSQFKCTNTNRCIP 3428
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
+ C+G +C EDE C +C+ C+ + CIP CD DC+D + ++
Sbjct: 3429 GIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPAN 3488
Query: 1732 CSDTWTLLGIGLAFLMTHITVAVLCFLANRKVPIR-KTEGSGNC 1774
C+ MT C + R +P R K +G +C
Sbjct: 3489 CTQ------------MTCGVDEFRCKDSGRCIPARWKCDGEDDC 3520
Score = 77.4 bits (189), Expect = 1e-13
Identities = 45/113 (39%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 1620 CIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGV 1679
C T C S CDG DC D SDE DCP P C F C + CIP CD
Sbjct: 2660 CERTSLCYAPSWVCDGANDCGDYSDERDCP-GVKRPRCPLNYFACPSGRCIPMSWTCDKE 2718
Query: 1680 PDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
DC EDE C NK CS C ++ CI CDG DC D + + C
Sbjct: 2719 DDCEHGEDETHC-NKFCSEAQFEC-QNHRCISKQWLCDGSDDCGDGSDEAAHC 2769
Score = 75.1 bits (183), Expect = 6e-13
Identities = 47/137 (34%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
Query: 1599 ECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCS 1658
+C G C+ DQF C + C+PL +CD DC+DGSDE C C
Sbjct: 3599 DCADGSDEKDCTPRCDMDQFQC-KSGHCIPLRWRCDADADCMDGSDEEACGTGVR--TCP 3655
Query: 1659 NMEFPCSTDECIPSLLLCDGVPDCHFNEDE--LICSNKSC-SNGALVCASSNSCIPAHQR 1715
EF C+ C P CDG DC N DE C+ C N C + C+ ++
Sbjct: 3656 LDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQ 3715
Query: 1716 CDGFADCMDFQLDESSC 1732
CDG +C D DE C
Sbjct: 3716 CDGTDNCGD-GTDEEDC 3731
Score = 74.7 bits (182), Expect = 8e-13
Identities = 43/119 (36%), Positives = 51/119 (42%), Gaps = 2/119 (1%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C FSC T CVP CDG +DC DG+DE C + EF C +CIP
Sbjct: 2774 CGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPK 2833
Query: 1673 LLLCDGVPDCHFNEDEL-ICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDES 1730
+CD DC DE C +C CA+ CDG DC D Q DE+
Sbjct: 2834 HFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHD-QSDEA 2891
Score = 74.3 bits (181), Expect = 1e-12
Identities = 45/126 (35%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 1611 SPCEA-DQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDEC 1669
S C A D+F C +C+ S CDG C D SDE P C CS C
Sbjct: 2522 SSCRAQDEFECANG-ECINFSLTCDGVPHCKDKSDEK--PSYCNSRRCKKTFRQCSNGRC 2578
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDE 1729
+ ++L C+G DC DE+ C+ +C G C +CI RC+ F DC D DE
Sbjct: 2579 VSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRC-RDGTCIGNSSRCNQFVDCEDAS-DE 2636
Query: 1730 SSCSDT 1735
+CS T
Sbjct: 2637 MNCSAT 2642
Score = 71.6 bits (174), Expect = 6e-12
Identities = 44/125 (35%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPC-STDECIP 1671
C QF C +C+ CDG +DC DGSDE T C F C T C+P
Sbjct: 2734 CSEAQFEC-QNHRCISKQWLCDGSDDCGDGSDEAAHCEGKT---CGPSSFSCPGTHVCVP 2789
Query: 1672 SLLLCDGVPDCHFNEDELICS----NKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQL 1727
LCDG DC DE I + N +C + +C + CIP H CD DC D
Sbjct: 2790 ERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMC-QNRQCIPKHFVCDHDRDCADGSD 2848
Query: 1728 DESSC 1732
+ C
Sbjct: 2849 ESPEC 2853
Score = 70.9 bits (172), Expect = 1e-11
Identities = 93/402 (23%), Positives = 136/402 (33%), Gaps = 85/402 (21%)
Query: 1397 ITDFLCRDK-KCIASHLLCDYKPDCSDRSDEA--------------HCAHYTSTTG--SC 1439
+ +F C+D +CI + CD + DC D SDE C + G C
Sbjct: 3496 VDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQC 3555
Query: 1440 NFETSSGNWTT--ACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGS 1497
+++ G+ + +C+ SE + A G I + D DH + GS
Sbjct: 3556 DYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKC-DGDHDC----------ADGS 3604
Query: 1498 KEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKR 1557
E F G C W D M + EE+
Sbjct: 3605 DEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMD----GSDEEA-------------- 3646
Query: 1558 TGWTYGSVPLSS---NSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCE 1614
G + PL N+ DG +D D+ EC P +P C+
Sbjct: 3647 CGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENP--EECARFVCPPNRPFRCK 3704
Query: 1615 ADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDC--PLSPTPPLCSNMEFPCSTDECIPS 1672
D+ C+ + +CDG ++C DG+DE DC P + T EF C C+ S
Sbjct: 3705 NDRV-------CLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSS 3757
Query: 1673 LLLCDGVPDCHFNEDELICS----NKSCSNGALVCASSNSC-----------------IP 1711
L C+ DC DE CS SC+ A +C C +P
Sbjct: 3758 SLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVP 3817
Query: 1712 AHQRCDGFADCMDFQLDESSCSDT--WTLLGIGLAFLMTHIT 1751
C +C+ F C++T L F+ TH T
Sbjct: 3818 GQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNT 3859
Score = 67.8 bits (164), Expect = 9e-11
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 1608 VQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPT---PPLCSNMEFPC 1664
V + C + C P S +C ED + +D + C +P+ PP C EF C
Sbjct: 802 VGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFAC 861
Query: 1665 STDECIPSLLLCDGVPDCHFNEDE--LICSNKSCSNGALVCASSNSCIPAHQRCDGFADC 1722
+ CI CDG DC N DE +C +C + C +N CIP CDG DC
Sbjct: 862 ANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKC-ENNRCIPNRWLCDGDNDC 920
Query: 1723 MDFQLDESSCS 1733
+ + DES+ +
Sbjct: 921 GNSE-DESNAT 930
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C +D+F C +C+P CDG DC + DE + S C +F C++ CIP
Sbjct: 895 CPSDRFKCENN-RCIPNRWLCDGDNDCGNSEDESNATCSART--CPPNQFSCASGRCIPI 951
Query: 1673 LLLCDGVPDCHFNEDE-LICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
CD DC DE C+ +C ++ CI + RCD DC D DE+
Sbjct: 952 SWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGD-NSDEAG 1010
Query: 1732 CS 1733
CS
Sbjct: 1011 CS 1012
Score = 65.9 bits (159), Expect = 4e-10
Identities = 42/144 (29%), Positives = 57/144 (39%), Gaps = 18/144 (12%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMD--CPLSPTPPLCSNMEFPCSTD 1667
P C QF+C + C+ +CDG DC DGSDE CP S N T+
Sbjct: 24 PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTE 83
Query: 1668 ECIPSLLLCDGVPDC--------HFNEDELICSNKSCSNGAL--------VCASSNSCIP 1711
C+P LC+GV DC H E + CS C + + C SS
Sbjct: 84 LCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQA 143
Query: 1712 AHQRCDGFADCMDFQLDESSCSDT 1735
+ C F +C + C++T
Sbjct: 144 DGKTCKDFDECSVYGTCSQLCTNT 167
Score = 63.5 bits (153), Expect = 2e-09
Identities = 97/380 (25%), Positives = 137/380 (36%), Gaps = 55/380 (14%)
Query: 1358 PEPECPRGRSALLKGPP-QEK---PNRRSALLSVGEISELCPEIT----DFLCRDKKCIA 1409
P P+C G A QE+ L + E LC + T F C + +CI
Sbjct: 850 PPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIP 909
Query: 1410 SHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSG-----NWTTACSLTQDSEDDLDW 1464
+ LCD DC + DE++ T F +SG +WT C L D D D
Sbjct: 910 NRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWT--CDLDDDCGDRSDE 967
Query: 1465 AIGSRIPAKALIPDSDHTPGSGQHFLYVN---------SSGSKEGSVARITTSKSFPASL 1515
+ P P + T +G+ + +N S E + +S F +
Sbjct: 968 SASCAYP--TCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNS 1024
Query: 1516 GMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKV 1575
G C W D G +E+ N + + G + +
Sbjct: 1025 GRCIPEHWTCDGD-NDCGDYS----DETHANC---TNQATRPPGGCHTDEFQCRLDGLCI 1076
Query: 1576 AFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDG 1635
DG+ D + D+ S E VT P C+ D CI + CDG
Sbjct: 1077 PLRWRCDGDTDCMDSSDEKSC--EGVTHVCDPSVKFGCK-DSARCI------SKAWVCDG 1127
Query: 1636 HEDCIDGSDEMDC-PLSPTPPLCSNMEFPC--STDECIPSLLLCDGVPDCHFNEDE-LIC 1691
DC D SDE +C L+ PP PC +T C+P LCDG DC DE +C
Sbjct: 1128 DNDCEDNSDEENCESLACRPP-----SHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELC 1182
Query: 1692 SNKSCSNGALVCASSNSCIP 1711
S +NG C+ + S P
Sbjct: 1183 DQCSLNNGG--CSHNCSVAP 1200
Score = 62.0 bits (149), Expect = 5e-09
Identities = 40/117 (34%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 1625 QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHF 1684
+CV C+G +DC DGSDE+ C C EF C CI + C+ DC
Sbjct: 2577 RCVSNMLWCNGADDCGDGSDEIPC----NKTACGVGEFRCRDGTCIGNSSRCNQFVDCED 2632
Query: 1685 NEDELICSNKSCSN-------GALV--CASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
DE+ CS CS+ G L C ++ C CDG DC D+ DE C
Sbjct: 2633 ASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYS-DERDC 2688
Score = 54.3 bits (129), Expect = 1e-06
Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 23/130 (17%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCS----TDE 1668
C+ ++ +C+ T CVP+S C+G +DC+DGSDE P C ++ CS
Sbjct: 72 CQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDE--------GPHCRELQGNCSRLGCQHH 123
Query: 1669 CIPSLLLCDGVPDCHFNED-ELICSNKSCSNGALVCASSNSCIPAHQRCDG--FADCMD- 1724
C+P+L DG P C+ N +L K+C + C+ +C DG C++
Sbjct: 124 CVPTL---DG-PTCYCNSSFQLQADGKTCKDFD-ECSVYGTCSQLCTNTDGSFICGCVEG 178
Query: 1725 --FQLDESSC 1732
Q D SC
Sbjct: 179 YLLQPDNRSC 188
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/142 (29%), Positives = 56/142 (39%), Gaps = 27/142 (19%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNME--------FPC 1664
C +F C +CDG DC D SDE +P P C++ E F C
Sbjct: 2858 CGPSEFRCANGRCLSSRQWECDGENDCHDQSDE-----APKNPHCTSQEHKCNASSQFLC 2912
Query: 1665 STDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSN----------SCIPAHQ 1714
S+ C+ LLC+G DC + DE C C + L S + C P +
Sbjct: 2913 SSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGFKCRCRPGFR 2972
Query: 1715 RCDGFADCMDFQLDESSCSDTW 1736
D C D +DE CS T+
Sbjct: 2973 LKDDGRTCAD--VDE--CSTTF 2990
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/58 (46%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 684 TLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC--VMEVCSFEKRSLCK 739
T PP C +EF CR DG CI +CD DC D SDE SC V VC + CK
Sbjct: 1056 TRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCK 1113
Score = 50.4 bits (119), Expect = 2e-05
Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTF----ICRTSSGRCDFEFDLCSWKQE 959
C D EFMC N+ CI K +CD DCAD SDE+ C S RC L S + E
Sbjct: 2818 CDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLSSRQWE 2877
Query: 960 KDEDFDWNLKASSIPAAGTEPAADHTLGNSS 990
D + D + ++ P + +H SS
Sbjct: 2878 CDGENDCHDQSDEAPKNPHCTSQEHKCNASS 2908
Score = 50.1 bits (118), Expect = 2e-05
Identities = 67/277 (24%), Positives = 91/277 (32%), Gaps = 27/277 (9%)
Query: 684 TLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVCSFEKRSLCKWYQ 742
T C N+F C S G CI CD DC D+SDE ASC C + C +
Sbjct: 930 TCSARTCPPNQFSCAS-GRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGR 988
Query: 743 PIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTAD 802
I ++ D++ + H + + + + + W D+ G + D
Sbjct: 989 CININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDE-- 1046
Query: 803 ILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKL-WAQTGQQGAQWKRAEVF 861
T CT G Q + D + L W G E
Sbjct: 1047 --------THANCTNQATRPPGGCHTDEFQCRL--DGLCIPLRWRCDGDTDCMDSSDEKS 1096
Query: 862 LGIRSHT---QIVFRAKRGISYIGDVAVDDISFQDCSPLLSPER----KCTDHEFMCANK 914
+H + F K I V D DC E C CAN
Sbjct: 1097 CEGVTHVCDPSVKFGCKDSARCISKAWVCD-GDNDCEDNSDEENCESLACRPPSHPCANN 1155
Query: 915 H--CIAKDKLCDFVNDCADNSDETTFI--CRTSSGRC 947
C+ DKLCD +DC D SDE C ++G C
Sbjct: 1156 TSVCLPPDKLCDGNDDCGDGSDEGELCDQCSLNNGGC 1192
Score = 48.9 bits (115), Expect = 4e-05
Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 15/76 (19%)
Query: 901 ERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSD----------ETTFIC---RTSSGR- 946
ER C ++F C N C+ CD+ NDC DNSD E+ F C R +GR
Sbjct: 3533 ERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRW 3592
Query: 947 -CDFEFDLCSWKQEKD 961
CD + D EKD
Sbjct: 3593 KCDGDHDCADGSDEKD 3608
Score = 47.8 bits (112), Expect = 1e-04
Identities = 21/46 (45%), Positives = 25/46 (54%)
Query: 895 SPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
+P P +C EF CAN CI + CD NDC DNSDE +C
Sbjct: 845 NPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALC 890
Score = 47.8 bits (112), Expect = 1e-04
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 1108 DSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTF---- 1163
D E + PT F PL C+NG+C + C+ ++CGDN+DE C SC+
Sbjct: 963 DRSDESASCAYPTCF-PLTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQFK 1021
Query: 1164 --------EKGWCGWQNSQADNFDWVLGVGSHQSLRPP 1193
E C N D D ++Q+ RPP
Sbjct: 1022 CNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPP 1059
Score = 47.8 bits (112), Expect = 1e-04
Identities = 19/42 (45%), Positives = 24/42 (57%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT 115
CS+ +F C SG+CI + CD DC D SDE A C+ T
Sbjct: 1015 CSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQAT 1056
Score = 47.8 bits (112), Expect = 1e-04
Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQDS 1458
+F+C++++CI H +CD+ DC+D SDE+ Y T G F ++G ++ D
Sbjct: 2822 EFMCQNRQCIPKHFVCDHDRDCADGSDESPECEY-PTCGPSEFRCANGRCLSSRQWECDG 2880
Query: 1459 EDD 1461
E+D
Sbjct: 2881 END 2883
Score = 47.4 bits (111), Expect = 1e-04
Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCK 739
P C+ +F CR CI K +CD + DCPD SDEA E+C K C+
Sbjct: 24 PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAP---EICPQSKAQRCQ 73
Score = 47.4 bits (111), Expect = 1e-04
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
C EF C + +CI + CD DC D SDE PA C +H TC + C
Sbjct: 854 CQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQH-TCPSDRFKC 902
Score = 46.2 bits (108), Expect = 3e-04
Identities = 64/272 (23%), Positives = 95/272 (34%), Gaps = 50/272 (18%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLL 749
C EF CR DG CI +C+ DC D SDE +C C
Sbjct: 2605 CGVGEFRCR-DGTCIGNSSRCNQFVDCEDASDEMNCSATDC------------------- 2644
Query: 750 QDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIIS 809
S+ FR G+ G+ E R S+ + + W + G + D D
Sbjct: 2645 --SSYFRLGV-KGVLFQPCE---RTSLCYAPS----WVCDGANDCGDYSDERD----CPG 2690
Query: 810 LTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQ 869
+ P+C L ++ +G + K+D+ + G F S Q
Sbjct: 2691 VKRPRCPLNYFACPSGRCIPMSWTCDKEDDC---------EHGEDETHCNKFC---SEAQ 2738
Query: 870 IVFRAKRGIS--YIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKH-CIAKDKLCDFV 926
+ R IS ++ D DD + C F C H C+ + LCD
Sbjct: 2739 FECQNHRCISKQWLCD-GSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGD 2797
Query: 927 NDCADNSDETTFICRTSSGRCDFEFDLCSWKQ 958
DCAD +DE+ + CD +C +Q
Sbjct: 2798 KDCADGADESIAAGCLYNSTCDDREFMCQNRQ 2829
Score = 45.8 bits (107), Expect = 4e-04
Identities = 79/334 (23%), Positives = 116/334 (34%), Gaps = 47/334 (14%)
Query: 682 PVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEAS--CVMEVCSFEKRSLCK 739
P +PP C EF C ++ CI++ KCD DC D SDEA C C + R C+
Sbjct: 846 PSYVPPPQCQPGEFAC-ANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSD-RFKCE 903
Query: 740 WYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGD 799
+ IP L D + GN + + R + + G + + D
Sbjct: 904 NNRCIPNRWLCDGDN---DCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDD 960
Query: 800 TADILTPIISLTGPKC-TLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRA 858
D S P C L +T NG + ++ DN + G +
Sbjct: 961 CGDRSDESASCAYPTCFPLTQFTCNNGRCI-NINWRCDNDNDCGDNSDEAGCSHS----- 1014
Query: 859 EVFLGIRSHTQIVFRAKR---------GISYIGDVAVDDISFQDCSPLLSPERKCTDHEF 909
S TQ + R G + GD + D+ + P C EF
Sbjct: 1015 ------CSSTQFKCNSGRCIPEHWTCDGDNDCGDYS-DETHANCTNQATRPPGGCHTDEF 1067
Query: 910 MC-ANKHCIAKDKLCDFVNDCADNSDE-----TTFICRTS-------SGRCDFEFDLCSW 956
C + CI CD DC D+SDE T +C S S RC + +W
Sbjct: 1068 QCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISK----AW 1123
Query: 957 KQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSS 990
+ D D + N + + P + N+S
Sbjct: 1124 VCDGDNDCEDNSDEENCESLACRPPSHPCANNTS 1157
Score = 44.7 bits (104), Expect = 8e-04
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 67 QTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
+T K CS +F C + +CI+K+ +CD DC D SDE A + TC S C
Sbjct: 2727 ETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE--AAHCEGKTCGPSSFSC 2781
Score = 44.3 bits (103), Expect = 0.001
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 9/99 (9%)
Query: 425 SQPFHLSLDKVSLGI---YDGVSAIDDIRFENCTLPLPAES--CEGLDHFWCRHTRACIE 479
++PF D+V L I DG D E P A + C+ F CR+ R
Sbjct: 3698 NRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSS 3757
Query: 480 KLRLCDLVDDCGDRTDEVNCA--PEL-QCNFETGICNWE 515
LR C++ DDCGD +DE +C+ P+L C IC E
Sbjct: 3758 SLR-CNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDE 3795
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 13/65 (20%)
Query: 461 ESCEGLDH-------FWCRHTRACIEKLRLCDLVDDCGDRTDEVNC------APELQCNF 507
+SCEG+ H F C+ + CI K +CD +DC D +DE NC P C
Sbjct: 1095 KSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCAN 1154
Query: 508 ETGIC 512
T +C
Sbjct: 1155 NTSVC 1159
Score = 43.5 bits (101), Expect = 0.002
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
C +D F C + +CI +CD DC + DE ATCS TC
Sbjct: 895 CPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSAR-TC 936
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
CS EF C +G+CIA CD DC+D SDE T CD + C
Sbjct: 3575 CSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCT----PRCDMDQFQC 3620
Score = 43.5 bits (101), Expect = 0.002
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 12/86 (13%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN--ECGS---------SCTFEKGWCGWQ 1171
CPL +C+N C L C+ D+CGDN+DEN EC C ++ C W
Sbjct: 3654 CPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDR-VCLWI 3712
Query: 1172 NSQADNFDWVLGVGSHQSLRPPKDHT 1197
Q D D + PP HT
Sbjct: 3713 GRQCDGTDNCGDGTDEEDCEPPTAHT 3738
Score = 43.1 bits (100), Expect = 0.002
Identities = 18/34 (52%), Positives = 21/34 (61%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDP 107
C EF C + QCI K VCD +DC+D SDE P
Sbjct: 2818 CDDREFMCQNRQCIPKHFVCDHDRDCADGSDESP 2851
Score = 43.1 bits (100), Expect = 0.002
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 29/170 (17%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-----C-----D 117
+Q K ++ +F C+SG+C+A+ +C+ + DC D SDE ++ L+ C D
Sbjct: 2899 SQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCED 2958
Query: 118 FESGF-CGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSF--IYLEAQRSPGVA 174
+ GF C P + ++ FP + N HGS+ + +E G
Sbjct: 2959 LKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCIN-THGSYKCLCVEGYAPRG-- 3015
Query: 175 KLGSPVLTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGN---LQKQG 221
G P K +T P + +N + +LDG+ L KQG
Sbjct: 3016 --GDPHSCKAVTDEEPFLI--------FANRYYLRKLNLDGSNYTLLKQG 3055
Score = 43.1 bits (100), Expect = 0.002
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 887 DDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT---FICRTS 943
DD P PE KC +F C+ C +CD NDC DNSDE +C S
Sbjct: 3357 DDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPS 3416
Query: 944 SGRC 947
+C
Sbjct: 3417 QFKC 3420
Score = 43.1 bits (100), Expect = 0.002
Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 887 DDISFQDCSPLLSPERKCTDH-EFMCANKHCIAKDKLCDFVNDCADNSDE 935
D +DC P + C D EF+C N+ C++ C+ +DC D SDE
Sbjct: 3724 DGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDE 3773
Score = 43.1 bits (100), Expect = 0.002
Identities = 16/37 (43%), Positives = 25/37 (67%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
C + +FLCR+++C++S L C+ DC D SDE C+
Sbjct: 3741 CKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCS 3777
Score = 42.7 bits (99), Expect = 0.003
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 687 PHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV 746
P C+++EF C ++G CI KCD +DC D SDE C C ++ CK IP+
Sbjct: 3572 PRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCTPR-CDMDQFQ-CKSGHCIPL 3628
Query: 747 HLLQDSN 753
D++
Sbjct: 3629 RWRCDAD 3635
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 68 TQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC 116
T S + C ++F C SG+CI CD DC D SDE A+C+ + TC
Sbjct: 930 TCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDES-ASCA-YPTC 976
Score = 42.4 bits (98), Expect = 0.004
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 2/49 (4%)
Query: 64 ACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK 112
ACG + C DEF C + C CD DC D SDE+P C++
Sbjct: 3646 ACGT--GVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECAR 3692
Score = 41.6 bits (96), Expect = 0.007
Identities = 16/35 (45%), Positives = 21/35 (60%)
Query: 77 DEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCS 111
DEF C +G+CI CD C D+SDE P+ C+
Sbjct: 2528 DEFECANGECINFSLTCDGVPHCKDKSDEKPSYCN 2562
Score = 41.6 bits (96), Expect = 0.007
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWV 1181
CPL Y C +G+C + +C+ D+C DE C C+ + C QN + + W+
Sbjct: 2696 CPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFEC--QNHRCISKQWL 2752
Score = 41.6 bits (96), Expect = 0.007
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 74 CSADEFPCT-SGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCD 117
C DEF C SG+CI CD DC D SDE C + TC+
Sbjct: 3494 CGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDER-TCE 3537
Score = 41.2 bits (95), Expect = 0.009
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 9/72 (12%)
Query: 900 PERKCTDHEFMCA-NKHCIAKDKLCDFVNDCADNSDE----TTFICRTSSGRCDFEFDLC 954
PE C ++F C+ K CI + +CD NDC D SDE T C RC + C
Sbjct: 3449 PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCK-DSGRC 3507
Query: 955 ---SWKQEKDED 963
WK + ++D
Sbjct: 3508 IPARWKCDGEDD 3519
Score = 41.2 bits (95), Expect = 0.009
Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 17/86 (19%)
Query: 1389 EISELCPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-------AHYTSTTG 1437
E E C E T F C++ +C+ CDY DC D SDE C + ++ G
Sbjct: 3526 EPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANG 3585
Query: 1438 SCNFETSSGNWTTACSLTQDSEDDLD 1463
C +G W C D D D
Sbjct: 3586 RC----IAGRW--KCDGDHDCADGSD 3605
Score = 40.4 bits (93), Expect = 0.016
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
C + FLC +C+A LLC+ + DC D SDE C
Sbjct: 2904 CNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGC 2939
Score = 40.0 bits (92), Expect = 0.021
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 4/53 (7%)
Query: 74 CSADEFPCTSGQCIA-KESVCDSRQDCSDESDE---DPATCSKHLTCDFESGF 122
C EF C +G+C++ ++ CD DC D+SDE +P S+ C+ S F
Sbjct: 2858 CGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQF 2910
Score = 40.0 bits (92), Expect = 0.021
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 682 PVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
P P C +F C S G C CD DC D SDEA+C + VC
Sbjct: 3366 PPDCPEFKCRPGQFQC-STGICTNPAFICDGDNDCQDNSDEANCDIHVC 3413
Score = 39.7 bits (91), Expect = 0.027
Identities = 22/48 (45%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 908 EFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCS 955
EF CAN CI CD V C D SDE C +S RC F CS
Sbjct: 2529 EFECANGECINFSLTCDGVPHCKDKSDEKPSYC--NSRRCKKTFRQCS 2574
Score = 39.7 bits (91), Expect = 0.027
Identities = 15/38 (39%), Positives = 21/38 (55%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSS 1160
C +R+C NG+C CN D+CGD +DE C +
Sbjct: 2566 CKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKT 2603
Score = 39.7 bits (91), Expect = 0.027
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 684 TLPPHNCT-DNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLC 738
T H C ++F+C S G C+ + C+ + DC D SDE C + C K S C
Sbjct: 2898 TSQEHKCNASSQFLC-SSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGC 2952
Score = 39.7 bits (91), Expect = 0.027
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 16/80 (20%)
Query: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 951
+DC+P +C +F C + HCI CD DC D SDE C T C +
Sbjct: 3607 KDCTP------RCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEA--CGTGVRTCPLDE 3658
Query: 952 DLC--------SWKQEKDED 963
C +WK + ++D
Sbjct: 3659 FQCNNTLCKPLAWKCDGEDD 3678
Score = 39.7 bits (91), Expect = 0.027
Identities = 16/33 (48%), Positives = 19/33 (57%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDED 106
C D+F C SG CI CD+ DC D SDE+
Sbjct: 3613 CDMDQFQCKSGHCIPLRWRCDADADCMDGSDEE 3645
Score = 39.3 bits (90), Expect = 0.035
Identities = 17/34 (50%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 689 NCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE 722
NCT ++F+C++D CI KCD + DC D SDE
Sbjct: 3333 NCTASQFVCKND-KCIPFWWKCDTEDDCGDHSDE 3365
Score = 39.3 bits (90), Expect = 0.035
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 5/41 (12%)
Query: 687 PHNCTD-----NEFICRSDGHCIEKMQKCDFKYDCPDKSDE 722
P NCT +EF C+ G CI KCD + DC D SDE
Sbjct: 3486 PANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDE 3526
Score = 38.9 bits (89), Expect = 0.046
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 1398 TDFLCRDKKCIASHLLCDYKPDCSDRSDE-AHCAHYTSTTGSCNFETSSG---NWTTACS 1453
+ F+C++ KCI CD + DC D SDE C + G F+ S+G N C
Sbjct: 3337 SQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPG--QFQCSTGICTNPAFICD 3394
Query: 1454 LTQDSEDDLDWA 1465
D +D+ D A
Sbjct: 3395 GDNDCQDNSDEA 3406
Score = 38.9 bits (89), Expect = 0.046
Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Query: 74 CSADEFPCT-SGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
C+ ++F C+ + +CI + VCD DC D SDE PA C++ +TC + C
Sbjct: 3453 CAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE-PANCTQ-MTCGVDEFRC 3501
Score = 38.9 bits (89), Expect = 0.046
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 5/45 (11%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENECG-----SSCTFEKGWCG 1169
C N +C CN D+CGD +DE +C +SC CG
Sbjct: 3749 CRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICG 3793
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 1391 SELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDE-AHC 1429
++ C E F C++ +CI+ LCD DC D SDE AHC
Sbjct: 2731 NKFCSE-AQFECQNHRCISKQWLCDGSDDCGDGSDEAAHC 2769
Score = 38.5 bits (88), Expect = 0.060
Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 14/136 (10%)
Query: 1580 DLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEAD-QFSCIYTLQCVPLSGKCDGHED 1638
+ DG D D+ P C + Q C A QF C + +CV + C+G +D
Sbjct: 2877 ECDGENDCHDQSDEAPKNPHCTS------QEHKCNASSQFLCS-SGRCVAEALLCNGQDD 2929
Query: 1639 CIDGSDEMDCPLSPTPPLCSNMEFPCSTD-ECIPSLLLCDGVPDCHFNEDELICSNKSCS 1697
C D SDE C ++ S CS D E + C P +D C++
Sbjct: 2930 CGDSSDERGCHIN---ECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDEC 2986
Query: 1698 NGALVCASSNSCIPAH 1713
+ C S CI H
Sbjct: 2987 STTFPC--SQRCINTH 3000
Score = 38.5 bits (88), Expect = 0.060
Identities = 16/38 (42%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 899 SPERKCT-DHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
S E KC +F+C++ C+A+ LC+ +DC D+SDE
Sbjct: 2899 SQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDE 2936
Score = 38.5 bits (88), Expect = 0.060
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDP 107
C+A +F C + +CI CD+ DC D SDE P
Sbjct: 3334 CTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPP 3367
Score = 38.5 bits (88), Expect = 0.060
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE-ASCVMEVCSFEK 734
P C N+F C CI ++ CD DC D SDE A+C C ++
Sbjct: 3449 PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDE 3498
Score = 38.5 bits (88), Expect = 0.060
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
C +F C+++ C+ +CD+ DC D SDE SC CS
Sbjct: 3536 CEPYQFRCKNN-RCVPGRWQCDYDNDCGDNSDEESCTPRPCS 3576
Score = 38.5 bits (88), Expect = 0.060
Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
C ++F C+S GHCI +CD DC D SDE +C
Sbjct: 3613 CDMDQFQCKS-GHCIPLRWRCDADADCMDGSDEEAC 3647
Score = 38.1 bits (87), Expect = 0.079
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 72 KLCSADEFPCTSG-QCIAKESVCDSRQDCSDESDEDPATC 110
K CS +F C CI+K CD +DC D SDE P C
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEIC 64
Score = 38.1 bits (87), Expect = 0.079
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN-ECGSSCTFEKGWCGWQNSQADNFDW 1180
CP C +G+C + +C+ D+CGD +DE+ C F N + N +W
Sbjct: 936 CPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININW 994
Score = 38.1 bits (87), Expect = 0.079
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----TTFICRTSSGRC 947
CT +F+C N CI CD +DC D+SDE F CR +C
Sbjct: 3334 CTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQC 3381
Score = 38.1 bits (87), Expect = 0.079
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL 114
C +F C++G C +CD DC D SDE A C H+
Sbjct: 3374 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDE--ANCDIHV 3412
Score = 37.7 bits (86), Expect = 0.10
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 7/58 (12%)
Query: 461 ESCEGL-----DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICN 513
E+CE L H +T C+ +LCD DDCGD +DE QC+ G C+
Sbjct: 1138 ENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELCD--QCSLNNGGCS 1193
Score = 37.7 bits (86), Expect = 0.10
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 7/94 (7%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTG-SC-NFETSSGNWTTA 1451
CP + F C +CI CD + DC DE HC + S C N S W
Sbjct: 2696 CP-LNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQW--L 2752
Query: 1452 CSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGS 1485
C + D D D A + K P S PG+
Sbjct: 2753 CDGSDDCGDGSDEA--AHCEGKTCGPSSFSCPGT 2784
Score = 37.7 bits (86), Expect = 0.10
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1108 DSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGW 1167
D+ EE P P C C NG+C C+ +C D +DE +C C ++
Sbjct: 3563 DNSDEESCTPRP---CSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQ 3619
Query: 1168 C 1168
C
Sbjct: 3620 C 3620
Score = 37.4 bits (85), Expect = 0.13
Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 10/64 (15%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDE------VNCAPELQCNFETGIC---NWEQD 517
+ F C R CI CDL DDCGDR+DE C P Q G C NW D
Sbjct: 939 NQFSCASGR-CIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCD 997
Query: 518 AKDD 521
+D
Sbjct: 998 NDND 1001
Score = 37.4 bits (85), Expect = 0.13
Identities = 15/36 (41%), Positives = 18/36 (50%)
Query: 70 SRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
++ C EF C G CI S C+ DC D SDE
Sbjct: 2601 NKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDE 2636
Score = 37.4 bits (85), Expect = 0.13
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 13/67 (19%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQC-----NFETG-------ICNWEQ 516
F C++ + CI CD DDCGD +DE PE +C TG IC+ +
Sbjct: 3339 FVCKNDK-CIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDN 3397
Query: 517 DAKDDFD 523
D +D+ D
Sbjct: 3398 DCQDNSD 3404
Score = 37.4 bits (85), Expect = 0.13
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 11/65 (16%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDE-VNC------APELQCNFETGIC---NWEQ 516
+ F C T+ CI ++ +CD +DC D +DE NC E +C ++G C W+
Sbjct: 3456 NQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCK-DSGRCIPARWKC 3514
Query: 517 DAKDD 521
D +DD
Sbjct: 3515 DGEDD 3519
Score = 37.0 bits (84), Expect = 0.18
Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 893 DCSPLLSPERK---CTDHEFMCANKH-CIAKDKLCDFVNDCADNSDETTFICRTSSGRC 947
D +P + P+ K C +E C C+ +LC+ V DC D SDE CR G C
Sbjct: 58 DEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGPH-CRELQGNC 115
Score = 37.0 bits (84), Expect = 0.18
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
Query: 465 GLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFET 509
G+D F C+ + CI CD DDCGD +DE P+ +C+ T
Sbjct: 3495 GVDEFRCKDSGRCIPARWKCDGEDDCGDGSDE----PKEECDERT 3535
Score = 36.6 bits (83), Expect = 0.23
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK 112
R C + F C SG+CI CD DC E ED C+K
Sbjct: 2693 RPRCPLNYFACPSGRCIPMSWTCDKEDDC--EHGEDETHCNK 2732
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 15/79 (18%)
Query: 1122 FCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDE------NECGSS---------CTFEKG 1166
FC EC N +C + C+ D+CGD +DE CG S C E+
Sbjct: 2733 FCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERW 2792
Query: 1167 WCGWQNSQADNFDWVLGVG 1185
C AD D + G
Sbjct: 2793 LCDGDKDCADGADESIAAG 2811
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTDEV-------------NCAPELQCNFETGICNWE 515
F C++ R CI K LCD DDCGD +DE +C C E +C+ +
Sbjct: 2739 FECQNHR-CISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGD 2797
Query: 516 QDAKDDFDWTRSQG 529
+D D D + + G
Sbjct: 2798 KDCADGADESIAAG 2811
Score = 36.6 bits (83), Expect = 0.23
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 72 KLCSADEFPCTSGQ-CIAKESVCDSRQDCSDESDED-PATCSKHLTCDFESGFC 123
K C F C C+ + +CD +DC+D +DE A C + TCD C
Sbjct: 2772 KTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMC 2825
Score = 36.2 bits (82), Expect = 0.30
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 902 RKCTDHEFMCANK-HCIAKDKLCDFVNDCADNSDETTFIC-RTSSGRC 947
+ C+ +F C ++ CI+K CD DC D SDE IC ++ + RC
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRC 72
Score = 36.2 bits (82), Expect = 0.30
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 15/77 (19%)
Query: 453 NCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC-----APELQCNF 507
+C P +C L F C + R CI CD +DCGD +DE C + + +CN
Sbjct: 970 SCAYP----TCFPLTQFTCNNGR-CININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCN- 1023
Query: 508 ETGIC---NWEQDAKDD 521
+G C +W D +D
Sbjct: 1024 -SGRCIPEHWTCDGDND 1039
Score = 36.2 bits (82), Expect = 0.30
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 1402 CRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGS--CNFETSSGNWTTACSLTQDSE 1459
C + +C+++ L C+ DC D SDE C G C T GN ++ C+ D E
Sbjct: 2573 CSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRCRDGTCIGN-SSRCNQFVDCE 2631
Query: 1460 DDLD 1463
D D
Sbjct: 2632 DASD 2635
Score = 36.2 bits (82), Expect = 0.30
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 1397 ITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
+ +F CRD CI + C+ DC D SDE +C+
Sbjct: 2607 VGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCS 2640
Score = 36.2 bits (82), Expect = 0.30
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 1398 TDFLCRDKKCIASHLL-CDYKPDCSDRSDEA-HCAHYTSTTGSCN----FETSSGNWTTA 1451
++F C + +C++S CD + DC D+SDEA H TS CN F SSG
Sbjct: 2861 SEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAE 2920
Query: 1452 CSLTQDSED 1460
L +D
Sbjct: 2921 ALLCNGQDD 2929
Score = 36.2 bits (82), Expect = 0.30
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 12/67 (17%)
Query: 469 FWCRHTRACIEKLRLCDLVDDCGDRTD-----EVNCAP-ELQCNF------ETGICNWEQ 516
F C +T CI + C+ D+CGD D EV CAP + QC+ +C+ +
Sbjct: 3418 FKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDN 3477
Query: 517 DAKDDFD 523
D D D
Sbjct: 3478 DCVDGSD 3484
Score = 36.2 bits (82), Expect = 0.30
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGN 1447
C E ++F C + +CIA CD DC+D SDE C T F+ SG+
Sbjct: 3575 CSE-SEFSCANGRCIAGRWKCDGDHDCADGSDEKDC---TPRCDMDQFQCKSGH 3624
Score = 36.2 bits (82), Expect = 0.30
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
Query: 675 TPPETSVPVTLPPHNCTDN-EFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVME 728
T E P T +C D EF+CR+ C+ +C+ DC D SDE C ++
Sbjct: 3726 TDEEDCEPPTAHTTHCKDKKEFLCRNQ-RCLSSSLRCNMFDDCGDGSDEEDCSID 3779
Score = 35.8 bits (81), Expect = 0.39
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE---ASCVMEVCSFEKRSLCKWYQPIPV 746
C + F C C+ + CD DC D +DE A C+ ++ +C+ Q IP
Sbjct: 2774 CGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPK 2833
Query: 747 HLLQD 751
H + D
Sbjct: 2834 HFVCD 2838
Score = 35.8 bits (81), Expect = 0.39
Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 8/80 (10%)
Query: 1388 GEISELCPEIT----DFLCR-DKKCIASHLLCDYKPDCSDRSDE-AHCAHYTSTTGSCNF 1441
GE CPE+T F C K+CI +CD DC D SDE A+C T G F
Sbjct: 3442 GEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQ--MTCGVDEF 3499
Query: 1442 ETSSGNWTTACSLTQDSEDD 1461
D EDD
Sbjct: 3500 RCKDSGRCIPARWKCDGEDD 3519
Score = 35.8 bits (81), Expect = 0.39
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 459 PAESCEGLD----HFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP----ELQCNFETG 510
P E C+ F C++ R C+ CD +DCGD +DE +C P E + + G
Sbjct: 3527 PKEECDERTCEPYQFRCKNNR-CVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANG 3585
Query: 511 IC---NWEQDAKDD 521
C W+ D D
Sbjct: 3586 RCIAGRWKCDGDHD 3599
Score = 35.8 bits (81), Expect = 0.39
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFCGWE 126
EF C + +C++ C+ DC D SDE+ + LT C + CG E
Sbjct: 3746 EFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDE 3795
Score = 35.4 bits (80), Expect = 0.51
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA-SCVMEVC 730
C D EF+C++ CI K CD DC D SDE+ C C
Sbjct: 2818 CDDREFMCQNR-QCIPKHFVCDHDRDCADGSDESPECEYPTC 2858
Score = 35.4 bits (80), Expect = 0.51
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 3/44 (6%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDED---PATCSK 112
+ C +F C + +C+ CD DC D SDE+ P CS+
Sbjct: 3534 RTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSE 3577
Score = 35.0 bits (79), Expect = 0.67
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 20/64 (31%)
Query: 78 EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCS-----------------KHLTCDFES 120
+F C +G+CI CD+ DC D SDE A CS +H TCD ++
Sbjct: 981 QFTCNNGRCININWRCDNDNDCGDNSDE--AGCSHSCSSTQFKCNSGRCIPEHWTCDGDN 1038
Query: 121 GFCG 124
CG
Sbjct: 1039 D-CG 1041
Score = 34.7 bits (78), Expect = 0.87
Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
Query: 74 CSADEFPCT-SGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCD 117
C DEF C G CI CD DC D SDE H+ CD
Sbjct: 1062 CHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHV-CD 1105
Score = 34.7 bits (78), Expect = 0.87
Identities = 17/39 (43%), Positives = 18/39 (46%)
Query: 902 RKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC 940
R C EF C N C CD +DC DNSDE C
Sbjct: 3652 RTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC 3690
Score = 34.3 bits (77), Expect = 1.1
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 460 AESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCN 506
A+ C+ +H C T C+ RLC+ V DC D +DE ELQ N
Sbjct: 69 AQRCQPNEHN-CLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGN 114
Score = 34.3 bits (77), Expect = 1.1
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 10/64 (15%)
Query: 467 DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGIC---NWEQD 517
D F C + R CI LCD +DCG+ DE N P Q + +G C +W D
Sbjct: 898 DRFKCENNR-CIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCD 956
Query: 518 AKDD 521
DD
Sbjct: 957 LDDD 960
Score = 34.3 bits (77), Expect = 1.1
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 1385 LSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDE 1426
L+ ++ C +F C + +CI L CD P C D+SDE
Sbjct: 2515 LTCRAVNSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDE 2556
Score = 34.3 bits (77), Expect = 1.1
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 10/61 (16%)
Query: 471 CRHTRACIEKLRLCDLVDDCGDRTDEVNC----APELQCNF---ETGIC---NWEQDAKD 520
C T C +CD +DCGD +DE +C P N+ +G C +W D +D
Sbjct: 2660 CERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKED 2719
Query: 521 D 521
D
Sbjct: 2720 D 2720
Score = 33.9 bits (76), Expect = 1.5
Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 78 EFPCT-SGQCIAKESVCDSRQDCSDESDED 106
+F C S +CI+K VCD DC D SDE+
Sbjct: 1109 KFGCKDSARCISKAWVCDGDNDCEDNSDEE 1138
Score = 33.9 bits (76), Expect = 1.5
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 463 CEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
C F C R C+ + LC+ DDCGD +DE C
Sbjct: 2904 CNASSQFLCSSGR-CVAEALLCNGQDDCGDSSDERGC 2939
Score = 33.9 bits (76), Expect = 1.5
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 7/49 (14%)
Query: 1388 GEISELCPEITDFLCRDKK-------CIASHLLCDYKPDCSDRSDEAHC 1429
G+ S+ P+ +F CR + C +CD DC D SDEA+C
Sbjct: 3360 GDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC 3408
Score = 33.9 bits (76), Expect = 1.5
Identities = 13/44 (29%), Positives = 22/44 (50%)
Query: 688 HNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
H C ++F C + CI + +C+ + +C D DE C C+
Sbjct: 3411 HVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCA 3454
Score = 33.9 bits (76), Expect = 1.5
Identities = 11/28 (39%), Positives = 17/28 (60%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C N +C C++ ++CGDN+DE C
Sbjct: 3543 CKNNRCVPGRWQCDYDNDCGDNSDEESC 3570
Score = 33.9 bits (76), Expect = 1.5
Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 16/78 (20%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP-----ELQCN 506
E+CT P P E F C + R CI CD DC D +DE +C P + QC
Sbjct: 3568 ESCT-PRPCSESE----FSCANGR-CIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQC- 3620
Query: 507 FETGIC---NWEQDAKDD 521
++G C W DA D
Sbjct: 3621 -KSGHCIPLRWRCDADAD 3637
Score = 33.5 bits (75), Expect = 1.9
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 13/86 (15%)
Query: 1090 GDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCG 1149
GD +D ENC E LA P+ C + C ++ C+ D+CG
Sbjct: 1127 GDNDCEDNSDEENC--------ESLACRPPSHPCAN-----NTSVCLPPDKLCDGNDDCG 1173
Query: 1150 DNTDENECGSSCTFEKGWCGWQNSQA 1175
D +DE E C+ G C S A
Sbjct: 1174 DGSDEGELCDQCSLNNGGCSHNCSVA 1199
Score = 33.1 bits (74), Expect = 2.5
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 65 CGQTQSRKLCSADEFPCTSGQ-CIAKESVCDSRQDCSDESDEDP 107
C Q+++++ C +E C + C+ +C+ QDC D SDE P
Sbjct: 64 CPQSKAQR-CQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGP 106
Score = 33.1 bits (74), Expect = 2.5
Identities = 27/108 (25%), Positives = 38/108 (35%), Gaps = 18/108 (16%)
Query: 453 NCT--LPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDE-------------- 496
NCT P C D F CR CI CD DC D +DE
Sbjct: 1050 NCTNQATRPPGGCH-TDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSV 1108
Query: 497 -VNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNT 543
C +C + +C+ + D +D+ D + + P +NT
Sbjct: 1109 KFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNT 1156
Score = 33.1 bits (74), Expect = 2.5
Identities = 16/35 (45%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Query: 690 CTDNEFICRSDGHCIEKMQ-KCDFKYDCPDKSDEA 723
C +EF C ++G C+ Q +CD + DC D+SDEA
Sbjct: 2858 CGPSEFRC-ANGRCLSSRQWECDGENDCHDQSDEA 2891
Score = 33.1 bits (74), Expect = 2.5
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
C +G+C CN D+CGD++DE C
Sbjct: 2912 CSSGRCVAEALLCNGQDDCGDSSDERGC 2939
Score = 32.7 bits (73), Expect = 3.3
Identities = 14/43 (32%), Positives = 20/43 (46%)
Query: 893 DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
D P R+C C+N C++ C+ +DC D SDE
Sbjct: 2555 DEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDE 2597
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/32 (40%), Positives = 20/32 (62%), Gaps = 2/32 (6%)
Query: 81 CTSGQCIAKESVCDSRQDCSDESDEDPATCSK 112
C++G+C++ C+ DC D SDE P C+K
Sbjct: 2573 CSNGRCVSNMLWCNGADDCGDGSDEIP--CNK 2602
Score = 32.7 bits (73), Expect = 3.3
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 11/58 (18%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI-----CNWEQDAKDDFD 523
C+ + C+ DDCGD +DE+ C E +C T I CN D +D D
Sbjct: 2578 CVSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASD 2635
Score = 32.7 bits (73), Expect = 3.3
Identities = 19/61 (31%), Positives = 22/61 (36%)
Query: 1403 RDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDL 1462
R C A +CD DC D SDE C N+ S T D EDD
Sbjct: 2662 RTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDC 2721
Query: 1463 D 1463
+
Sbjct: 2722 E 2722
Score = 32.7 bits (73), Expect = 3.3
Identities = 14/49 (28%), Positives = 24/49 (48%), Gaps = 3/49 (6%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGS---SCTFEKGWC 1168
C + +C +G C L C+ +C D +DE CG+ +C ++ C
Sbjct: 3613 CDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQC 3661
Score = 32.3 bits (72), Expect = 4.3
Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 6/52 (11%)
Query: 74 CSADEFPCTSGQ--CIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
C PC + C+ + +CD DC D SDE C + C +G C
Sbjct: 1145 CRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEG-ELCDQ---CSLNNGGC 1192
Score = 32.3 bits (72), Expect = 4.3
Identities = 27/100 (27%), Positives = 39/100 (39%), Gaps = 10/100 (10%)
Query: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 951
+DC + P +C + F C + CI CD +DC DET S + + +
Sbjct: 2686 RDCPGVKRP--RCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQN 2743
Query: 952 DLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSG 991
C KQ W S G++ AA H G + G
Sbjct: 2744 HRCISKQ-------WLCDGSDDCGDGSDEAA-HCEGKTCG 2775
Score = 32.3 bits (72), Expect = 4.3
Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 7/69 (10%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTAC--- 1452
++ F C+ CI CD DC D SDE C T F+ ++ T C
Sbjct: 3614 DMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNN----TLCKPL 3669
Query: 1453 SLTQDSEDD 1461
+ D EDD
Sbjct: 3670 AWKCDGEDD 3678
Score = 32.3 bits (72), Expect = 4.3
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 1393 LCPEITDFLCR-DKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSC 1439
+CP F C+ D+ C+ CD +C D +DE C T+ T C
Sbjct: 3694 VCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHC 3741
Score = 32.0 bits (71), Expect = 5.6
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 7/57 (12%)
Query: 1102 NCLSLHDSVQEELAVPLPTGFCPLGYRECHN-GKCYRLEQSCNFVDNCGDNTDENEC 1157
+C D ++ V LP+ F +C N +C CN DNCGD DE +C
Sbjct: 3398 DCQDNSDEANCDIHVCLPSQF------KCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3448
Score = 31.6 bits (70), Expect = 7.4
Identities = 17/66 (25%), Positives = 25/66 (37%), Gaps = 15/66 (22%)
Query: 1129 ECHNGKCYRLEQSCNFVDNCGDNTDE--------------NECGSS-CTFEKGWCGWQNS 1173
EC NG+C +C+ V +C D +DE +C + C WC +
Sbjct: 2531 ECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADD 2590
Query: 1174 QADNFD 1179
D D
Sbjct: 2591 CGDGSD 2596
Score = 31.6 bits (70), Expect = 7.4
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 447 DDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC-APELQC 505
DD + +P +C G+ F CR CI C+ DC D +DE+NC A +
Sbjct: 2589 DDCGDGSDEIPCNKTAC-GVGEFRCRDG-TCIGNSSRCNQFVDCEDASDEMNCSATDCSS 2646
Query: 506 NFETGI 511
F G+
Sbjct: 2647 YFRLGV 2652
Score = 31.2 bits (69), Expect = 9.6
Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 1400 FLCRDK-KCIASHLLCDYKPDCSDRSDEA 1427
F CRD+ CI+ CD + DC D SDEA
Sbjct: 32 FACRDQITCISKGWRCDGERDCPDGSDEA 60
Score = 31.2 bits (69), Expect = 9.6
Identities = 13/45 (28%), Positives = 20/45 (44%)
Query: 1116 VPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSS 1160
+P C +G C +G C CN +C D +DE C ++
Sbjct: 2598 IPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSAT 2642
Score = 31.2 bits (69), Expect = 9.6
Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 14/76 (18%)
Query: 466 LDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA--------PELQCNFETGICN---W 514
+D F C+ CI CD DC D +DE C E QCN +C W
Sbjct: 3615 MDQFQCKSGH-CIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCN--NTLCKPLAW 3671
Query: 515 EQDAKDDFDWTRSQGP 530
+ D +DD + P
Sbjct: 3672 KCDGEDDCGDNSDENP 3687
Score = 31.2 bits (69), Expect = 9.6
Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 9/68 (13%)
Query: 677 PETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEV-----CS 731
PE PP+ F C++D C+ ++CD +C D +DE C C
Sbjct: 3687 PEECARFVCPPNR----PFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCK 3742
Query: 732 FEKRSLCK 739
+K LC+
Sbjct: 3743 DKKEFLCR 3750
>gi|61744471 low density lipoprotein receptor-related protein 8
isoform 1 precursor [Homo sapiens]
Length = 963
Score = 90.1 bits (222), Expect = 2e-17
Identities = 50/134 (37%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 1603 GGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEF 1662
GG P + CE DQF C +C+P +CD +DC+D SDE DCP C++ +F
Sbjct: 39 GGQGPAKD--CEKDQFQC-RNERCIPSVWRCDEDDDCLDHSDEDDCP----KKTCADSDF 91
Query: 1663 PCSTDECIPSLLLCDGVPDC--HFNEDELICSNKSCSNGALVCA-SSNSCIPAHQRCDGF 1719
C CI CDG +C +E E C+ + C L C +S+ C+PA RCDG
Sbjct: 92 TCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGE 151
Query: 1720 ADCMDFQLDESSCS 1733
DC + DE+ C+
Sbjct: 152 KDC-EGGADEAGCA 164
Score = 80.9 bits (198), Expect = 1e-14
Identities = 42/115 (36%), Positives = 57/115 (49%), Gaps = 8/115 (6%)
Query: 1613 CEADQFSCIYTL-QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C A++ SC T +CVP S +CDG +DC G+DE C LC+ EF C C+
Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCAT-----LCAPHEFQCGNRSCLA 181
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCA--SSNSCIPAHQRCDGFADCMD 1724
++ +CDG DC DE C++ +C C +CIP CD DC D
Sbjct: 182 AVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCED 236
Score = 60.8 bits (146), Expect = 1e-08
Identities = 33/83 (39%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 1610 PSPCE-ADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE 1668
P+ C A QF+C + +CV L +CDG DC D SDE DCPL C EF C
Sbjct: 256 PAACATASQFAC-RSGECVHLGWRCDGDRDCKDKSDEADCPLG----TCRGDEFQCGDGT 310
Query: 1669 CIPSLLLCDGVPDCHFNEDELIC 1691
C+ ++ C+ DC DE C
Sbjct: 311 CVLAIKHCNQEQDCPDGSDEAGC 333
Score = 55.5 bits (132), Expect = 5e-07
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 1657 CSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRC 1716
C +F C + CIPS+ CD DC + DE C K+C++ C + CI +C
Sbjct: 47 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-DNGHCIHERWKC 105
Query: 1717 DGFADCMDFQLDESSCSDT 1735
DG +C D DES + T
Sbjct: 106 DGEEECPDGS-DESEATCT 123
Score = 53.9 bits (128), Expect = 1e-06
Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSD--EASCVMEVCSFEKRS 736
P C D++F C +GHCI + KCD + +CPD SD EA+C +VC EK S
Sbjct: 82 PKKTCADSDFTC-DNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLS 133
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/115 (31%), Positives = 48/115 (41%), Gaps = 10/115 (8%)
Query: 1626 CVPLSGKCDGHEDCIDGSDEMD--CP-----LSPTPPLCSNM-EFPCSTDECIPSLLLCD 1677
C+P CD DC D SDE C + P C+ +F C + EC+ CD
Sbjct: 221 CIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLGWRCD 280
Query: 1678 GVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
G DC DE C +C C +C+ A + C+ DC D DE+ C
Sbjct: 281 GDRDCKDKSDEADCPLGTCRGDEFQC-GDGTCVLAIKHCNQEQDCPDGS-DEAGC 333
Score = 51.2 bits (121), Expect = 9e-06
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+K C+ +F C +G CI + CD ++C D SDE ATC+K + C E CG
Sbjct: 83 KKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCG 135
Score = 46.2 bits (108), Expect = 3e-04
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 674 PTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
P P TS P T ++F CRS G C+ +CD DC DKSDEA C + C
Sbjct: 248 PGPGATSAPAAC----ATASQFACRS-GECVHLGWRCDGDRDCKDKSDEADCPLGTC 299
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 883 DVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC-- 940
D +D DC P++ C D +F C N HCI + CD +C D SDE+ C
Sbjct: 70 DDCLDHSDEDDC-----PKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTK 124
Query: 941 ------RTSSGRCDFEFDLCSWKQEKDED 963
+ S G + SW+ + ++D
Sbjct: 125 QVCPAEKLSCGPTSHKCVPASWRCDGEKD 153
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDE----DPATCSKHLTCDFESG 121
LC+ EF C + C+A VCD DC D SDE DPA + C + G
Sbjct: 166 LCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGG 218
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-----------QCNF 507
PA+ CE D F CR+ R CI + CD DDC D +DE +C + C
Sbjct: 43 PAKDCEK-DQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIH 100
Query: 508 ETGICNWEQDAKDDFD-----WTRSQGPTPTLNTGP 538
E C+ E++ D D T+ P L+ GP
Sbjct: 101 ERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGP 136
Score = 42.4 bits (98), Expect = 0.004
Identities = 16/32 (50%), Positives = 20/32 (62%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C HEF C N+ C+A +CD +DC D SDE
Sbjct: 167 CAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDE 198
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCS-KHLTCDFESGFC 123
K C D+F C + +CI CD DC D SDED TC+ TCD +G C
Sbjct: 45 KDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCD--NGHC 98
Score = 41.6 bits (96), Expect = 0.007
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 5/75 (6%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTA-- 1451
C + F CR +C+ CD DC D+SDEA C T F+ G A
Sbjct: 259 CATASQFACRSGECVHLGWRCDGDRDCKDKSDEADCP--LGTCRGDEFQCGDGTCVLAIK 316
Query: 1452 -CSLTQDSEDDLDWA 1465
C+ QD D D A
Sbjct: 317 HCNQEQDCPDGSDEA 331
Score = 41.6 bits (96), Expect = 0.007
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
P C +EF C DG C+ ++ C+ + DCPD SDEA C+
Sbjct: 295 PLGTCRGDEFQC-GDGTCVLAIKHCNQEQDCPDGSDEAGCL 334
Score = 40.0 bits (92), Expect = 0.021
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
P +C ++F CR++ CI + +CD DC D SDE C + C+
Sbjct: 43 PAKDCEKDQFQCRNE-RCIPSVWRCDEDDDCLDHSDEDDCPKKTCA 87
Score = 40.0 bits (92), Expect = 0.021
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFC 123
C DEF C G C+ C+ QDC D SDE A C + L C +G C
Sbjct: 299 CRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDE--AGCLQGLNECLHNNGGC 347
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Query: 896 PLLS---PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----------TTFICRT 942
PLL P + C +F C N+ CI CD +DC D+SDE + F C
Sbjct: 36 PLLGGQGPAKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-- 93
Query: 943 SSGRCDFEFDLCSWKQEKDEDFD 965
+G C E C ++E + D
Sbjct: 94 DNGHCIHERWKCDGEEECPDGSD 116
Score = 38.9 bits (89), Expect = 0.046
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 66 GQTQSRKLCS-ADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
G T + C+ A +F C SG+C+ CD +DC D+SDE A C TC + CG
Sbjct: 251 GATSAPAACATASQFACRSGECVHLGWRCDGDRDCKDKSDE--ADCPLG-TCRGDEFQCG 307
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-------AHYTSTTGSCNFE 1442
E F CR+++CI S CD DC D SDE C + +T G C E
Sbjct: 48 EKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHE 101
Score = 37.4 bits (85), Expect = 0.13
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 5/43 (11%)
Query: 690 CTDNEFICRSDGH--CIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C EF C DG CI + CD ++DC D+SDEA+ E+C
Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAA---ELC 245
Score = 37.0 bits (84), Expect = 0.18
Identities = 14/32 (43%), Positives = 20/32 (62%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
+F C ++ C+A+ +CD DC D SDE CA
Sbjct: 171 EFQCGNRSCLAAVFVCDGDDDCGDGSDERGCA 202
Score = 35.8 bits (81), Expect = 0.39
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 74 CSADEFPCTS---GQCIAKESVCDSRQDCSDESDEDPATCSK 112
C EF C G CI + VCD + DC D SDE C +
Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAAELCGR 247
Score = 35.8 bits (81), Expect = 0.39
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 12/73 (16%)
Query: 462 SCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI---- 511
+C F CR + C+ CD DC D++DE +C E QC T +
Sbjct: 258 ACATASQFACR-SGECVHLGWRCDGDRDCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIK 316
Query: 512 -CNWEQDAKDDFD 523
CN EQD D D
Sbjct: 317 HCNQEQDCPDGSD 329
Score = 35.4 bits (80), Expect = 0.51
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 14/63 (22%)
Query: 475 RACIEKLRLCDLVDDCGDRTDEVNCAP------ELQCNFETG--------ICNWEQDAKD 520
R+C+ + +CD DDCGD +DE CA E +C + G +C+ + D +D
Sbjct: 177 RSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCED 236
Query: 521 DFD 523
D
Sbjct: 237 RSD 239
Score = 33.5 bits (75), Expect = 1.9
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 5/53 (9%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI-----CRTSSGRC 947
P C EF C + C+ K C+ DC D SDE + C ++G C
Sbjct: 295 PLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGC 347
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
+F C D C+ + C+ + DC D SDEA C
Sbjct: 303 EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Score = 32.0 bits (71), Expect = 5.6
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 8/50 (16%)
Query: 899 SPERKCTD-----HEFMCANKH---CIAKDKLCDFVNDCADNSDETTFIC 940
S ER C D EF C CI + +CD DC D SDE +C
Sbjct: 196 SDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAAELC 245
Score = 31.6 bits (70), Expect = 7.4
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query: 1394 CPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSS 1445
CP+ T DF C + CI CD + +C D SDE+ T T C E S
Sbjct: 81 CPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEA---TCTKQVCPAEKLS 133
Score = 31.6 bits (70), Expect = 7.4
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 68 TQSRKLCSADEFPC--TSGQCIAKESVCDSRQDCSDESDED--PATCSKHLTCDFESG 121
T ++++C A++ C TS +C+ CD +DC +DE C+ H +F+ G
Sbjct: 121 TCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATLCAPH---EFQCG 175
Score = 31.6 bits (70), Expect = 7.4
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C +EF C + C+ + CD DC D SDE C C
Sbjct: 167 CAPHEFQC-GNRSCLAAVFVCDGDDDCGDGSDERGCADPAC 206
Score = 31.6 bits (70), Expect = 7.4
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-QCNFETGICN 513
P +C G D F C C+ ++ C+ DC D +DE C L +C G C+
Sbjct: 295 PLGTCRG-DEFQCGDG-TCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGCS 348
>gi|61744467 low density lipoprotein receptor-related protein 8
isoform 3 precursor [Homo sapiens]
Length = 700
Score = 90.1 bits (222), Expect = 2e-17
Identities = 50/134 (37%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 1603 GGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEF 1662
GG P + CE DQF C +C+P +CD +DC+D SDE DCP C++ +F
Sbjct: 39 GGQGPAKD--CEKDQFQC-RNERCIPSVWRCDEDDDCLDHSDEDDCP----KKTCADSDF 91
Query: 1663 PCSTDECIPSLLLCDGVPDC--HFNEDELICSNKSCSNGALVCA-SSNSCIPAHQRCDGF 1719
C CI CDG +C +E E C+ + C L C +S+ C+PA RCDG
Sbjct: 92 TCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGE 151
Query: 1720 ADCMDFQLDESSCS 1733
DC + DE+ C+
Sbjct: 152 KDC-EGGADEAGCA 164
Score = 56.6 bits (135), Expect = 2e-07
Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Query: 1613 CEADQFSCIYTL-QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C A++ SC T +CVP S +CDG +DC G+DE C S C EF C C+
Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATS--LGTCRGDEFQCGDGTCVL 184
Query: 1672 SLLLCDGVPDCHFNEDELIC 1691
++ C+ DC DE C
Sbjct: 185 AIKHCNQEQDCPDGSDEAGC 204
Score = 55.5 bits (132), Expect = 5e-07
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 1657 CSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRC 1716
C +F C + CIPS+ CD DC + DE C K+C++ C + CI +C
Sbjct: 47 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-DNGHCIHERWKC 105
Query: 1717 DGFADCMDFQLDESSCSDT 1735
DG +C D DES + T
Sbjct: 106 DGEEECPDGS-DESEATCT 123
Score = 53.9 bits (128), Expect = 1e-06
Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSD--EASCVMEVCSFEKRS 736
P C D++F C +GHCI + KCD + +CPD SD EA+C +VC EK S
Sbjct: 82 PKKTCADSDFTC-DNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLS 133
Score = 51.2 bits (121), Expect = 9e-06
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+K C+ +F C +G CI + CD ++C D SDE ATC+K + C E CG
Sbjct: 83 KKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCG 135
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 883 DVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC-- 940
D +D DC P++ C D +F C N HCI + CD +C D SDE+ C
Sbjct: 70 DDCLDHSDEDDC-----PKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTK 124
Query: 941 ------RTSSGRCDFEFDLCSWKQEKDED 963
+ S G + SW+ + ++D
Sbjct: 125 QVCPAEKLSCGPTSHKCVPASWRCDGEKD 153
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-----------QCNF 507
PA+ CE D F CR+ R CI + CD DDC D +DE +C + C
Sbjct: 43 PAKDCEK-DQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIH 100
Query: 508 ETGICNWEQDAKDDFD-----WTRSQGPTPTLNTGP 538
E C+ E++ D D T+ P L+ GP
Sbjct: 101 ERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGP 136
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCS-KHLTCDFESGFC 123
K C D+F C + +CI CD DC D SDED TC+ TCD +G C
Sbjct: 45 KDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCD--NGHC 98
Score = 40.8 bits (94), Expect = 0.012
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
C +EF C DG C+ ++ C+ + DCPD SDEA C+
Sbjct: 170 CRGDEFQC-GDGTCVLAIKHCNQEQDCPDGSDEAGCL 205
Score = 40.4 bits (93), Expect = 0.016
Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 66 GQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFC 123
G S C DEF C G C+ C+ QDC D SDE A C + L C +G C
Sbjct: 162 GCATSLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDE--AGCLQGLNECLHNNGGC 218
Score = 40.0 bits (92), Expect = 0.021
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
P +C ++F CR++ CI + +CD DC D SDE C + C+
Sbjct: 43 PAKDCEKDQFQCRNE-RCIPSVWRCDEDDDCLDHSDEDDCPKKTCA 87
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Query: 896 PLLS---PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----------TTFICRT 942
PLL P + C +F C N+ CI CD +DC D+SDE + F C
Sbjct: 36 PLLGGQGPAKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-- 93
Query: 943 SSGRCDFEFDLCSWKQEKDEDFD 965
+G C E C ++E + D
Sbjct: 94 DNGHCIHERWKCDGEEECPDGSD 116
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-------AHYTSTTGSCNFE 1442
E F CR+++CI S CD DC D SDE C + +T G C E
Sbjct: 48 EKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHE 101
Score = 36.6 bits (83), Expect = 0.23
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Query: 1406 KCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTA---CSLTQDSEDDL 1462
KC+ + CD + DC +DEA CA T F+ G A C+ QD D
Sbjct: 140 KCVPASWRCDGEKDCEGGADEAGCATSLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGS 199
Query: 1463 DWA 1465
D A
Sbjct: 200 DEA 202
Score = 34.7 bits (78), Expect = 0.87
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
Query: 68 TQSRKLCSADEFPC--TSGQCIAKESVCDSRQDCSDESDEDPATCSKHL-TCDFESGFCG 124
T ++++C A++ C TS +C+ CD +DC +DE A C+ L TC + CG
Sbjct: 121 TCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADE--AGCATSLGTCRGDEFQCG 178
Score = 33.1 bits (74), Expect = 2.5
Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 5/49 (10%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI-----CRTSSGRC 947
C EF C + C+ K C+ DC D SDE + C ++G C
Sbjct: 170 CRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGC 218
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
+F C D C+ + C+ + DC D SDEA C
Sbjct: 174 EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 204
Score = 31.6 bits (70), Expect = 7.4
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query: 1394 CPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSS 1445
CP+ T DF C + CI CD + +C D SDE+ T T C E S
Sbjct: 81 CPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEA---TCTKQVCPAEKLS 133
>gi|65301119 low density lipoprotein receptor-related protein 8
isoform 4 precursor [Homo sapiens]
Length = 904
Score = 90.1 bits (222), Expect = 2e-17
Identities = 50/134 (37%), Positives = 69/134 (51%), Gaps = 11/134 (8%)
Query: 1603 GGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEF 1662
GG P + CE DQF C +C+P +CD +DC+D SDE DCP C++ +F
Sbjct: 39 GGQGPAKD--CEKDQFQC-RNERCIPSVWRCDEDDDCLDHSDEDDCP----KKTCADSDF 91
Query: 1663 PCSTDECIPSLLLCDGVPDC--HFNEDELICSNKSCSNGALVCA-SSNSCIPAHQRCDGF 1719
C CI CDG +C +E E C+ + C L C +S+ C+PA RCDG
Sbjct: 92 TCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGE 151
Query: 1720 ADCMDFQLDESSCS 1733
DC + DE+ C+
Sbjct: 152 KDC-EGGADEAGCA 164
Score = 80.9 bits (198), Expect = 1e-14
Identities = 42/115 (36%), Positives = 57/115 (49%), Gaps = 8/115 (6%)
Query: 1613 CEADQFSCIYTL-QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C A++ SC T +CVP S +CDG +DC G+DE C LC+ EF C C+
Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCAT-----LCAPHEFQCGNRSCLA 181
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCA--SSNSCIPAHQRCDGFADCMD 1724
++ +CDG DC DE C++ +C C +CIP CD DC D
Sbjct: 182 AVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCED 236
Score = 60.8 bits (146), Expect = 1e-08
Identities = 33/83 (39%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 1610 PSPCE-ADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDE 1668
P+ C A QF+C + +CV L +CDG DC D SDE DCPL C EF C
Sbjct: 256 PAACATASQFAC-RSGECVHLGWRCDGDRDCKDKSDEADCPLG----TCRGDEFQCGDGT 310
Query: 1669 CIPSLLLCDGVPDCHFNEDELIC 1691
C+ ++ C+ DC DE C
Sbjct: 311 CVLAIKHCNQEQDCPDGSDEAGC 333
Score = 55.5 bits (132), Expect = 5e-07
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Query: 1657 CSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRC 1716
C +F C + CIPS+ CD DC + DE C K+C++ C + CI +C
Sbjct: 47 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-DNGHCIHERWKC 105
Query: 1717 DGFADCMDFQLDESSCSDT 1735
DG +C D DES + T
Sbjct: 106 DGEEECPDGS-DESEATCT 123
Score = 53.9 bits (128), Expect = 1e-06
Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSD--EASCVMEVCSFEKRS 736
P C D++F C +GHCI + KCD + +CPD SD EA+C +VC EK S
Sbjct: 82 PKKTCADSDFTC-DNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLS 133
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/115 (31%), Positives = 48/115 (41%), Gaps = 10/115 (8%)
Query: 1626 CVPLSGKCDGHEDCIDGSDEMD--CP-----LSPTPPLCSNM-EFPCSTDECIPSLLLCD 1677
C+P CD DC D SDE C + P C+ +F C + EC+ CD
Sbjct: 221 CIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLGWRCD 280
Query: 1678 GVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
G DC DE C +C C +C+ A + C+ DC D DE+ C
Sbjct: 281 GDRDCKDKSDEADCPLGTCRGDEFQC-GDGTCVLAIKHCNQEQDCPDGS-DEAGC 333
Score = 51.2 bits (121), Expect = 9e-06
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 71 RKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
+K C+ +F C +G CI + CD ++C D SDE ATC+K + C E CG
Sbjct: 83 KKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCG 135
Score = 46.2 bits (108), Expect = 3e-04
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 674 PTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
P P TS P T ++F CRS G C+ +CD DC DKSDEA C + C
Sbjct: 248 PGPGATSAPAAC----ATASQFACRS-GECVHLGWRCDGDRDCKDKSDEADCPLGTC 299
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 883 DVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC-- 940
D +D DC P++ C D +F C N HCI + CD +C D SDE+ C
Sbjct: 70 DDCLDHSDEDDC-----PKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTK 124
Query: 941 ------RTSSGRCDFEFDLCSWKQEKDED 963
+ S G + SW+ + ++D
Sbjct: 125 QVCPAEKLSCGPTSHKCVPASWRCDGEKD 153
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDE----DPATCSKHLTCDFESG 121
LC+ EF C + C+A VCD DC D SDE DPA + C + G
Sbjct: 166 LCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGG 218
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-----------QCNF 507
PA+ CE D F CR+ R CI + CD DDC D +DE +C + C
Sbjct: 43 PAKDCEK-DQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIH 100
Query: 508 ETGICNWEQDAKDDFD-----WTRSQGPTPTLNTGP 538
E C+ E++ D D T+ P L+ GP
Sbjct: 101 ERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGP 136
Score = 42.4 bits (98), Expect = 0.004
Identities = 16/32 (50%), Positives = 20/32 (62%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C HEF C N+ C+A +CD +DC D SDE
Sbjct: 167 CAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDE 198
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPA---TCS-KHLTCDFESGFC 123
K C D+F C + +CI CD DC D SDED TC+ TCD +G C
Sbjct: 45 KDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCD--NGHC 98
Score = 41.6 bits (96), Expect = 0.007
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 5/75 (6%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTA-- 1451
C + F CR +C+ CD DC D+SDEA C T F+ G A
Sbjct: 259 CATASQFACRSGECVHLGWRCDGDRDCKDKSDEADCP--LGTCRGDEFQCGDGTCVLAIK 316
Query: 1452 -CSLTQDSEDDLDWA 1465
C+ QD D D A
Sbjct: 317 HCNQEQDCPDGSDEA 331
Score = 41.6 bits (96), Expect = 0.007
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
P C +EF C DG C+ ++ C+ + DCPD SDEA C+
Sbjct: 295 PLGTCRGDEFQC-GDGTCVLAIKHCNQEQDCPDGSDEAGCL 334
Score = 40.0 bits (92), Expect = 0.021
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
P +C ++F CR++ CI + +CD DC D SDE C + C+
Sbjct: 43 PAKDCEKDQFQCRNE-RCIPSVWRCDEDDDCLDHSDEDDCPKKTCA 87
Score = 40.0 bits (92), Expect = 0.021
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT-CDFESGFC 123
C DEF C G C+ C+ QDC D SDE A C + L C +G C
Sbjct: 299 CRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDE--AGCLQGLNECLHNNGGC 347
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Query: 896 PLLS---PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE----------TTFICRT 942
PLL P + C +F C N+ CI CD +DC D+SDE + F C
Sbjct: 36 PLLGGQGPAKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTC-- 93
Query: 943 SSGRCDFEFDLCSWKQEKDEDFD 965
+G C E C ++E + D
Sbjct: 94 DNGHCIHERWKCDGEEECPDGSD 116
Score = 38.9 bits (89), Expect = 0.046
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 66 GQTQSRKLCS-ADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
G T + C+ A +F C SG+C+ CD +DC D+SDE A C TC + CG
Sbjct: 251 GATSAPAACATASQFACRSGECVHLGWRCDGDRDCKDKSDE--ADCPLG-TCRGDEFQCG 307
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 7/54 (12%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-------AHYTSTTGSCNFE 1442
E F CR+++CI S CD DC D SDE C + +T G C E
Sbjct: 48 EKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHE 101
Score = 37.4 bits (85), Expect = 0.13
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 5/43 (11%)
Query: 690 CTDNEFICRSDGH--CIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C EF C DG CI + CD ++DC D+SDEA+ E+C
Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAA---ELC 245
Score = 37.0 bits (84), Expect = 0.18
Identities = 14/32 (43%), Positives = 20/32 (62%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
+F C ++ C+A+ +CD DC D SDE CA
Sbjct: 171 EFQCGNRSCLAAVFVCDGDDDCGDGSDERGCA 202
Score = 35.8 bits (81), Expect = 0.39
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 74 CSADEFPCTS---GQCIAKESVCDSRQDCSDESDEDPATCSK 112
C EF C G CI + VCD + DC D SDE C +
Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAAELCGR 247
Score = 35.8 bits (81), Expect = 0.39
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 12/73 (16%)
Query: 462 SCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI---- 511
+C F CR + C+ CD DC D++DE +C E QC T +
Sbjct: 258 ACATASQFACR-SGECVHLGWRCDGDRDCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIK 316
Query: 512 -CNWEQDAKDDFD 523
CN EQD D D
Sbjct: 317 HCNQEQDCPDGSD 329
Score = 35.4 bits (80), Expect = 0.51
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 14/63 (22%)
Query: 475 RACIEKLRLCDLVDDCGDRTDEVNCAP------ELQCNFETG--------ICNWEQDAKD 520
R+C+ + +CD DDCGD +DE CA E +C + G +C+ + D +D
Sbjct: 177 RSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCED 236
Query: 521 DFD 523
D
Sbjct: 237 RSD 239
Score = 33.5 bits (75), Expect = 1.9
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 5/53 (9%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI-----CRTSSGRC 947
P C EF C + C+ K C+ DC D SDE + C ++G C
Sbjct: 295 PLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGC 347
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
+F C D C+ + C+ + DC D SDEA C
Sbjct: 303 EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Score = 32.0 bits (71), Expect = 5.6
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 8/50 (16%)
Query: 899 SPERKCTD-----HEFMCANKH---CIAKDKLCDFVNDCADNSDETTFIC 940
S ER C D EF C CI + +CD DC D SDE +C
Sbjct: 196 SDERGCADPACGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAAELC 245
Score = 31.6 bits (70), Expect = 7.4
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query: 1394 CPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSS 1445
CP+ T DF C + CI CD + +C D SDE+ T T C E S
Sbjct: 81 CPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEA---TCTKQVCPAEKLS 133
Score = 31.6 bits (70), Expect = 7.4
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 68 TQSRKLCSADEFPC--TSGQCIAKESVCDSRQDCSDESDED--PATCSKHLTCDFESG 121
T ++++C A++ C TS +C+ CD +DC +DE C+ H +F+ G
Sbjct: 121 TCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCATLCAPH---EFQCG 175
Score = 31.6 bits (70), Expect = 7.4
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C +EF C + C+ + CD DC D SDE C C
Sbjct: 167 CAPHEFQC-GNRSCLAAVFVCDGDDDCGDGSDERGCADPAC 206
Score = 31.6 bits (70), Expect = 7.4
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPEL-QCNFETGICN 513
P +C G D F C C+ ++ C+ DC D +DE C L +C G C+
Sbjct: 295 PLGTCRG-DEFQCGDG-TCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHNNGGCS 348
>gi|157384998 low density lipoprotein receptor-related protein 4 [Homo
sapiens]
Length = 1905
Score = 89.7 bits (221), Expect = 2e-17
Identities = 51/122 (41%), Positives = 64/122 (52%), Gaps = 4/122 (3%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C +F C C+ CDG DC DGSDE +CP + P C+ EF C+ CI
Sbjct: 148 CSDKEFRCSDG-SCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILD 206
Query: 1673 LLLCDGVPDCHFNEDELIC-SNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESS 1731
+ CDG DC DE C S++ C +G +C S CI A RCDG ADC D Q DE +
Sbjct: 207 IYHCDGDDDCGDWSDESDCSSHQPCRSGEFMC-DSGLCINAGWRCDGDADC-DDQSDERN 264
Query: 1732 CS 1733
C+
Sbjct: 265 CT 266
Score = 85.1 bits (209), Expect = 6e-16
Identities = 56/154 (36%), Positives = 71/154 (46%), Gaps = 14/154 (9%)
Query: 1582 DGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCID 1641
DG+ D D S C + P P PC ++F C Y +C+ CDG +DC D
Sbjct: 168 DGDTDC----KDGSDEENCPSAVPAP----PCNLEEFQCAYG-RCILDIYHCDGDDDCGD 218
Query: 1642 GSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGAL 1701
SDE DC S P C + EF C + CI + CDG DC DE C+ C+
Sbjct: 219 WSDESDCS-SHQP--CRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQF 275
Query: 1702 VCASSNSCIPAHQRCDGFADCMDFQLDESSCSDT 1735
C S C+ RCDG DC D DE +C +T
Sbjct: 276 RC-HSGRCVRLSWRCDGEDDCAD-NSDEENCENT 307
Score = 81.6 bits (200), Expect = 6e-15
Identities = 49/148 (33%), Positives = 64/148 (43%), Gaps = 23/148 (15%)
Query: 1594 ISFTPECVTGGPVPVQPSPCEADQFSCIYTL----QCVPLSGKCDGHEDCIDGSDEMDCP 1649
++ +PEC C F+C + C+P +CDG DC D SDE C
Sbjct: 19 LASSPECA-----------CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCI 67
Query: 1650 LSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSC 1709
L P CS ++F C +CI +CDG DC + DE C + C C + C
Sbjct: 68 L----PTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPC-QNGYC 122
Query: 1710 IPAHQRCDGFADC---MDFQLDESSCSD 1734
I + CDG DC D Q D CSD
Sbjct: 123 IRSLWHCDGDNDCGDNSDEQCDMRKCSD 150
Score = 79.3 bits (194), Expect = 3e-14
Identities = 96/354 (27%), Positives = 127/354 (35%), Gaps = 57/354 (16%)
Query: 1407 CIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNW---TTACSLTQDSEDDLD 1463
CI + CD DC D SDE C T +F +G + C D EDD D
Sbjct: 44 CIPAQWQCDGDNDCGDHSDEDGC--ILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSD 101
Query: 1464 WAIGSRIPAKALIPD-----SDHTPGSGQHFLYVNSSG--SKEGSVARITTSKSFPASLG 1516
P + D + + S H N G S E R + K F S G
Sbjct: 102 ---EQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDG 158
Query: 1517 MCTVRFWFYMID----------------PRSMGILKVYTIEESGLNILVWSVIGNKRTGW 1560
C W+ D P L+ + + ++ G+ G
Sbjct: 159 SCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGD 218
Query: 1561 TYGSVPLSSNSPFKVA-FEAD----------LDGNEDIFIALDDISFTPECVTGGPVPVQ 1609
SS+ P + F D DG+ D DD S C T
Sbjct: 219 WSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDAD----CDDQSDERNCTT------- 267
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDEC 1669
S C A+QF C ++ +CV LS +CDG +DC D SDE +C + +P C+ +F C C
Sbjct: 268 -SMCTAEQFRC-HSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQ-CALDQFLCWNGRC 324
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSN-SCIPAHQRCDGFADC 1722
I LC+GV DC N DE N G C +N C Q G C
Sbjct: 325 IGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQC 378
Score = 52.0 bits (123), Expect = 5e-06
Identities = 34/96 (35%), Positives = 42/96 (43%), Gaps = 12/96 (12%)
Query: 887 DDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI------- 939
DD QDC P R+C + EF C N +CI CD NDC DNSDE +
Sbjct: 98 DDSDEQDCPP-----RECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKE 152
Query: 940 CRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPA 975
R S G C E C + + D S++PA
Sbjct: 153 FRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPA 188
Score = 49.3 bits (116), Expect = 3e-05
Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Query: 883 DVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDET-TFICR 941
D D+ ++C SP+ C +F+C N CI + KLC+ VNDC DNSDE+ CR
Sbjct: 293 DDCADNSDEENCENTGSPQ--CALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCR 350
Query: 942 TSSG--RCDFEFDLCSWK 957
+G C+ C+ K
Sbjct: 351 PRTGEENCNVNNGGCAQK 368
Score = 48.1 bits (113), Expect = 8e-05
Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 10/80 (12%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCN----- 506
ENC +PA C L+ F C + R CI + CD DDCGD +DE +C+ C
Sbjct: 180 ENCPSAVPAPPCN-LEEFQCAYGR-CILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFM 237
Query: 507 FETGIC---NWEQDAKDDFD 523
++G+C W D D D
Sbjct: 238 CDSGLCINAGWRCDGDADCD 257
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIP 745
PP C ++EF C++ G+CI + CD DC D SDE C M CS +K C I
Sbjct: 106 PPRECEEDEFPCQN-GYCIRSLWHCDGDNDCGDNSDE-QCDMRKCS-DKEFRCSDGSCIA 162
Query: 746 VHLLQDSNT 754
H D +T
Sbjct: 163 EHWYCDGDT 171
Score = 46.6 bits (109), Expect = 2e-04
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Query: 882 GDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICR 941
GD D S + C RKC+D EF C++ CIA+ CD DC D SDE
Sbjct: 131 GDNDCGDNSDEQCDM-----RKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSA 185
Query: 942 TSSGRCDFEFDLCSW 956
+ C+ E C++
Sbjct: 186 VPAPPCNLEEFQCAY 200
Score = 45.1 bits (105), Expect = 6e-04
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 65 CGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLT----CDFES 120
C T S + C+ D+F C +G+CI + +C+ DC D SDE P + T C+ +
Sbjct: 304 CENTGSPQ-CALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNN 362
Query: 121 GFC 123
G C
Sbjct: 363 GGC 365
Score = 44.3 bits (103), Expect = 0.001
Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 10/60 (16%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC---DF--ESGFC---GW 125
C+ +EF C G+CI CD DC D SDE + CS H C +F +SG C GW
Sbjct: 191 CNLEEFQCAYGRCILDIYHCDGDDDCGDWSDE--SDCSSHQPCRSGEFMCDSGLCINAGW 248
Score = 43.9 bits (102), Expect = 0.001
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 16/76 (21%)
Query: 1120 TGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSS----------------CTF 1163
T C CH+G+C RL C+ D+C DN+DE C ++ C
Sbjct: 267 TSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIG 326
Query: 1164 EKGWCGWQNSQADNFD 1179
++ C N DN D
Sbjct: 327 QRKLCNGVNDCGDNSD 342
Score = 43.9 bits (102), Expect = 0.001
Identities = 17/51 (33%), Positives = 27/51 (52%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
+C+A++F C SG+C+ CD DC+D SDE+ + C + C
Sbjct: 269 MCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLC 319
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDED---PATCSK-HLTCDFESGFC 123
CS +F C +G+CI + VCD DC D+SDE P C + C ++G+C
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPC--QNGYC 122
Score = 43.5 bits (101), Expect = 0.002
Identities = 22/46 (47%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE--DPATCS-KHLTC 116
C DEFPC +G CI CD DC D SDE D CS K C
Sbjct: 110 CEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRC 155
Score = 43.5 bits (101), Expect = 0.002
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 5/89 (5%)
Query: 882 GDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFI-- 939
GD D S ++ P P C EF CA CI CD +DC D SDE+
Sbjct: 169 GDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSH 228
Query: 940 --CRTSSGRCDFEFDL-CSWKQEKDEDFD 965
CR+ CD + W+ + D D D
Sbjct: 229 QPCRSGEFMCDSGLCINAGWRCDGDADCD 257
Score = 43.5 bits (101), Expect = 0.002
Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 21/112 (18%)
Query: 882 GDVAVDDISFQ-DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT--- 937
GD DD S + +C+ + CT +F C + C+ CD +DCADNSDE
Sbjct: 252 GDADCDDQSDERNCTTSM-----CTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCEN 306
Query: 938 ----------FICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTE 979
F+C +GRC + LC+ + ++ D + + + P G E
Sbjct: 307 TGSPQCALDQFLC--WNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEE 356
Score = 42.7 bits (99), Expect = 0.003
Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEK 734
C EF+C S G CI +CD DC D+SDE +C +C+ E+
Sbjct: 231 CRSGEFMCDS-GLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQ 274
Score = 42.4 bits (98), Expect = 0.004
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 67 QTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDED 106
Q RK CS EF C+ G CIA+ CD DC D SDE+
Sbjct: 142 QCDMRK-CSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEE 180
Score = 41.2 bits (95), Expect = 0.009
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEV----CSFEK 734
C+D EF C SDG CI + CD DC D SDE +C V C+ E+
Sbjct: 148 CSDKEFRC-SDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEE 195
Score = 40.8 bits (94), Expect = 0.012
Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFE 1442
+F C D CIA H CD DC D SDE +C CN E
Sbjct: 152 EFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAP-PCNLE 194
Score = 39.7 bits (91), Expect = 0.027
Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 12/73 (16%)
Query: 899 SPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---TTFIC-----RTSSGRCDFE 950
S + C EFMC + CI CD DC D SDE TT +C R SGRC
Sbjct: 226 SSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRC--- 282
Query: 951 FDLCSWKQEKDED 963
SW+ + ++D
Sbjct: 283 -VRLSWRCDGEDD 294
Score = 39.7 bits (91), Expect = 0.027
Identities = 19/42 (45%), Positives = 22/42 (52%)
Query: 70 SRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCS 111
S + C + EF C SG CI CD DC D+SDE T S
Sbjct: 227 SHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTS 268
Score = 39.3 bits (90), Expect = 0.035
Identities = 18/60 (30%), Positives = 28/60 (46%)
Query: 1397 ITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQ 1456
+ FLC + +CI LC+ DC D SDE+ + TG N ++G C + +
Sbjct: 314 LDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVR 373
Score = 38.1 bits (87), Expect = 0.079
Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 21/123 (17%)
Query: 441 DGVSAIDDIRFE-NCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC 499
DG + DD E NCT + C + F C H+ C+ CD DDC D +DE NC
Sbjct: 251 DGDADCDDQSDERNCTTSM----CTA-EQFRC-HSGRCVRLSWRCDGEDDCADNSDEENC 304
Query: 500 ----APEL----------QCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLG 545
+P+ +C + +CN D D+ D + Q P N G
Sbjct: 305 ENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGG 364
Query: 546 TAK 548
A+
Sbjct: 365 CAQ 367
Score = 38.1 bits (87), Expect = 0.079
Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
CT +F C S G C+ +CD + DC D SDE +C
Sbjct: 270 CTAEQFRCHS-GRCVRLSWRCDGEDDCADNSDEENC 304
Score = 38.1 bits (87), Expect = 0.079
Identities = 18/48 (37%), Positives = 26/48 (54%)
Query: 1108 DSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDEN 1155
D+ EE + C L C NG+C + CN V++CGDN+DE+
Sbjct: 297 DNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDES 344
Score = 37.4 bits (85), Expect = 0.13
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C+ +F C N CI + +CD NDC D+SDE
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDE 102
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 1399 DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQDS 1458
+F+C CI + CD DC D+SDE +C TS + F SG S D
Sbjct: 235 EFMCDSGLCINAGWRCDGDADCDDQSDERNCT--TSMCTAEQFRCHSGR-CVRLSWRCDG 291
Query: 1459 EDD 1461
EDD
Sbjct: 292 EDD 294
Score = 36.6 bits (83), Expect = 0.23
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 678 ETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
E + P +P C EF C + G CI + CD DC D SDE+ C
Sbjct: 179 EENCPSAVPAPPCNLEEFQC-AYGRCILDIYHCDGDDDCGDWSDESDC 225
Score = 36.2 bits (82), Expect = 0.30
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 11/70 (15%)
Query: 1090 GDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCG 1149
GD D ENC S AVP P C L +C G+C C+ D+CG
Sbjct: 169 GDTDCKDGSDEENCPS---------AVPAPP--CNLEEFQCAYGRCILDIYHCDGDDDCG 217
Query: 1150 DNTDENECGS 1159
D +DE++C S
Sbjct: 218 DWSDESDCSS 227
Score = 35.8 bits (81), Expect = 0.39
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
Query: 899 SPERKCTDHEFMCANKH-----CIAKDKLCDFVNDCADNSDETTFICRTSS--------G 945
SPE C F CA CI CD NDC D+SDE I T S G
Sbjct: 22 SPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNG 81
Query: 946 RCDFEFDLCSWKQEKDEDFD 965
+C +C + ++D D
Sbjct: 82 KCIRRSWVCDGDNDCEDDSD 101
Score = 34.7 bits (78), Expect = 0.87
Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%)
Query: 686 PPHNCTDNEFICR----SDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
P C + F C + CI +CD DC D SDE C++ CS
Sbjct: 23 PECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCS 72
Score = 34.7 bits (78), Expect = 0.87
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C+ +F C +G CI + CD DC D SDE C C
Sbjct: 71 CSPLDFHC-DNGKCIRRSWVCDGDNDCEDDSDEQDCPPREC 110
Score = 34.7 bits (78), Expect = 0.87
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 18/101 (17%)
Query: 447 DDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEV----NCA-P 501
DD ++C P CE D F C++ CI L CD +DCGD +DE C+
Sbjct: 98 DDSDEQDC----PPRECEE-DEFPCQNGY-CIRSLWHCDGDNDCGDNSDEQCDMRKCSDK 151
Query: 502 ELQCN-----FETGICNWEQDAKDDFDWTR--SQGPTPTLN 535
E +C+ E C+ + D KD D S P P N
Sbjct: 152 EFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCN 192
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 17/79 (21%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP------ELQC 505
+ C LP +C LD F C + + CI + +CD +DC D +DE +C P E C
Sbjct: 64 DGCILP----TCSPLD-FHCDNGK-CIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPC 117
Query: 506 NFETGIC---NWEQDAKDD 521
+ G C W D +D
Sbjct: 118 --QNGYCIRSLWHCDGDND 134
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 1118 LPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
LPT PL + C NGKC R C+ ++C D++DE +C
Sbjct: 68 LPT-CSPLDFH-CDNGKCIRRSWVCDGDNDCEDDSDEQDC 105
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 15/74 (20%)
Query: 465 GLDHFWCRHTR----ACIEKLRLCDLVDDCGDRTDEVNC-----------APELQCNFET 509
G HF C + CI CD +DCGD +DE C +C +
Sbjct: 28 GRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGKCIRRS 87
Query: 510 GICNWEQDAKDDFD 523
+C+ + D +DD D
Sbjct: 88 WVCDGDNDCEDDSD 101
Score = 33.5 bits (75), Expect = 1.9
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 12/87 (13%)
Query: 1388 GEISELCPE--------ITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSC 1439
G E CP + +F C +CI CD DC D SDE+ C+ + S
Sbjct: 176 GSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSH-QPCRSG 234
Query: 1440 NFETSSG---NWTTACSLTQDSEDDLD 1463
F SG N C D +D D
Sbjct: 235 EFMCDSGLCINAGWRCDGDADCDDQSD 261
Score = 32.7 bits (73), Expect = 3.3
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 10/77 (12%)
Query: 1394 CP----EITDFLCRDKKCIASHLLCDYKPDCSDRSDE----AHCA--HYTSTTGSCNFET 1443
CP E +F C++ CI S CD DC D SDE C+ + + GSC E
Sbjct: 105 CPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEH 164
Query: 1444 SSGNWTTACSLTQDSED 1460
+ T C D E+
Sbjct: 165 WYCDGDTDCKDGSDEEN 181
Score = 32.3 bits (72), Expect = 4.3
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 15/106 (14%)
Query: 426 QPFHLSLDKVSLGIY--DGVSAIDDIRFEN-CTLPLPAESCEGLDHFWCRHTRACIEKLR 482
+ F + + L IY DG D E+ C+ P S E F C + CI
Sbjct: 194 EEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGE----FMC-DSGLCINAGW 248
Query: 483 LCDLVDDCGDRTDEVNCAPEL----QCNFETGIC---NWEQDAKDD 521
CD DC D++DE NC + Q +G C +W D +DD
Sbjct: 249 RCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDD 294
Score = 32.0 bits (71), Expect = 5.6
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 12/62 (19%)
Query: 1130 CHNGKCYRLEQSCNFVDNCGDNTDE----NECG--------SSCTFEKGWCGWQNSQADN 1177
C NG C R C+ ++CGDN+DE +C SC E +C D
Sbjct: 117 CQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDG 176
Query: 1178 FD 1179
D
Sbjct: 177 SD 178
Score = 31.2 bits (69), Expect = 9.6
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSS-CTFEKGWC 1168
C G C +G C C+ +C D +DE C +S CT E+ C
Sbjct: 231 CRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRC 277
>gi|148727288 low density lipoprotein receptor-related protein 6 [Homo
sapiens]
Length = 1613
Score = 87.0 bits (214), Expect = 1e-16
Identities = 45/128 (35%), Positives = 66/128 (51%), Gaps = 10/128 (7%)
Query: 1609 QPSPCEADQFSCIY-TLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTD 1667
+P C QF+C + C+P++ +CDG +C D SDE++C P+CS +F C++
Sbjct: 1245 EPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNC------PVCSESQFQCASG 1298
Query: 1668 ECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQL 1727
+CI L C+G +C DE C C CA + CI H++CD DC D +
Sbjct: 1299 QCIDGALRCNGDANCQDKSDEKNC-EVLCLIDQFRCA-NGQCIGKHKKCDHNVDCSD-KS 1355
Query: 1728 DESSCSDT 1735
DE C T
Sbjct: 1356 DELDCYPT 1363
Score = 47.8 bits (112), Expect = 1e-04
Identities = 19/33 (57%), Positives = 22/33 (66%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
LC D+F C +GQCI K CD DCSD+SDE
Sbjct: 1325 LCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDE 1357
Score = 43.5 bits (101), Expect = 0.002
Identities = 22/48 (45%), Positives = 26/48 (54%)
Query: 888 DISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
D + QD S + E C +F CAN CI K K CD DC+D SDE
Sbjct: 1310 DANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDE 1357
Score = 42.0 bits (97), Expect = 0.005
Identities = 18/36 (50%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
C ++F C ++G CI K +KCD DC DKSDE C
Sbjct: 1326 CLIDQFRC-ANGQCIGKHKKCDHNVDCSDKSDELDC 1360
Score = 41.6 bits (96), Expect = 0.007
Identities = 16/33 (48%), Positives = 20/33 (60%)
Query: 1397 ITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
I F C + +CI H CD+ DCSD+SDE C
Sbjct: 1328 IDQFRCANGQCIGKHKKCDHNVDCSDKSDELDC 1360
Score = 37.7 bits (86), Expect = 0.10
Identities = 15/33 (45%), Positives = 20/33 (60%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
+CS +F C SGQCI C+ +C D+SDE
Sbjct: 1287 VCSESQFQCASGQCIDGALRCNGDANCQDKSDE 1319
Score = 37.7 bits (86), Expect = 0.10
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 8/99 (8%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT--FICRTSSGRCDFEFDLCSWKQEK- 960
C++ +F CA+ CI C+ +C D SDE +C RC C K +K
Sbjct: 1288 CSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRC--ANGQCIGKHKKC 1345
Query: 961 DEDFDWNLKASSIPAAGTE---PAADHTLGNSSGHYIFI 996
D + D + K+ + TE P A +T+G+ G + I
Sbjct: 1346 DHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGVIVTI 1384
Score = 37.7 bits (86), Expect = 0.10
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLL 749
C++++F C S G CI+ +C+ +C DKSDE +C EV + C Q I H
Sbjct: 1288 CSESQFQCAS-GQCIDGALRCNGDANCQDKSDEKNC--EVLCLIDQFRCANGQCIGKHKK 1344
Query: 750 QDSN 753
D N
Sbjct: 1345 CDHN 1348
Score = 37.4 bits (85), Expect = 0.13
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 16/100 (16%)
Query: 1394 CPEITD--FLCRDKKCIASHLLCDYKPDCSDRSDEAHCA------HYTSTTGSCNFETSS 1445
CP ++ F C +CI L C+ +C D+SDE +C + G C +
Sbjct: 1285 CPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKK 1344
Query: 1446 GNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGS 1485
+ CS D D+LD P + P + +T GS
Sbjct: 1345 CDHNVDCS---DKSDELDC-----YPTEEPAPQATNTVGS 1376
Score = 36.6 bits (83), Expect = 0.23
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 4/52 (7%)
Query: 453 NCTLPLPAESCEGL---DHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAP 501
NC ++CE L D F C + + CI K + CD DC D++DE++C P
Sbjct: 1312 NCQDKSDEKNCEVLCLIDQFRCANGQ-CIGKHKKCDHNVDCSDKSDELDCYP 1362
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 687 PHNCTDNEFIC-RSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
P C+ +F C + CI +CD +C D SDE +C VCS
Sbjct: 1246 PPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNC--PVCS 1289
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 1112 EELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWC 1168
+EL P+ C +C +G+C CN NC D +DE C C ++ C
Sbjct: 1281 DELNCPV----CSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRC 1333
Score = 32.0 bits (71), Expect = 5.6
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 64 ACGQTQSRKLCSADEFPCTSGQ--CIAKESVCDSRQDCSDESDE 105
+CG+ + CS +F C +G+ CI CD +C D SDE
Sbjct: 1242 SCGEPPT---CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDE 1282
>gi|4504975 low density lipoprotein receptor precursor [Homo sapiens]
Length = 860
Score = 84.7 bits (208), Expect = 7e-16
Identities = 49/136 (36%), Positives = 63/136 (46%), Gaps = 20/136 (14%)
Query: 1613 CEADQFSCIYTL-QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIP 1671
C++ FSC + +C+P +CDG DC +GSDE CP P CS EF C +CI
Sbjct: 68 CKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCP----PKTCSQDEFRCHDGKCIS 123
Query: 1672 SLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMD------- 1724
+CD DC DE C +C + C +S++CIP CD DC D
Sbjct: 124 RQFVCDSDRDCLDGSDEASCPVLTCGPASFQC-NSSTCIPQLWACDNDPDCEDGSDEWPQ 182
Query: 1725 -------FQLDESSCS 1733
FQ D S CS
Sbjct: 183 RCRGLYVFQGDSSPCS 198
Score = 75.9 bits (185), Expect = 3e-13
Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 48/168 (28%)
Query: 1610 PSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPL------------- 1656
P C D+F C + +C+ CD DC+DGSDE CP+ P
Sbjct: 106 PKTCSQDEFRC-HDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQL 164
Query: 1657 --------------------------------CSNMEFPCSTDECIPSLLLCDGVPDCHF 1684
CS EF C + ECI S CDG PDC
Sbjct: 165 WACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKD 224
Query: 1685 NEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
DE C+ +C C+ N CI ++CD DC D DE C
Sbjct: 225 KSDEENCAVATCRPDEFQCSDGN-CIHGSRQCDREYDCKDMS-DEVGC 270
Score = 74.7 bits (182), Expect = 8e-13
Identities = 46/123 (37%), Positives = 58/123 (47%), Gaps = 9/123 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE-MDCPLSPTPPLCSNMEFPCS--TDEC 1669
CE ++F C +C+ CDG +C DGSDE + LS T C + +F C + C
Sbjct: 27 CERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVT---CKSGDFSCGGRVNRC 82
Query: 1670 IPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDE 1729
IP CDG DC DE C K+CS C CI CD DC+D DE
Sbjct: 83 IPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRC-HDGKCISRQFVCDSDRDCLDGS-DE 140
Query: 1730 SSC 1732
+SC
Sbjct: 141 ASC 143
Score = 69.7 bits (169), Expect = 2e-11
Identities = 41/116 (35%), Positives = 55/116 (47%), Gaps = 6/116 (5%)
Query: 1611 SPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECI 1670
SPC A +F C+ + +C+ S +CDG DC D SDE +C ++ C EF CS CI
Sbjct: 195 SPCSAFEFHCL-SGECIHSSWRCDGGPDCKDKSDEENCAVAT----CRPDEFQCSDGNCI 249
Query: 1671 PSLLLCDGVPDCHFNEDELICSNKS-CSNGALVCASSNSCIPAHQRCDGFADCMDF 1725
CD DC DE+ C N + C S CI + C+ DC D+
Sbjct: 250 HGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW 305
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/367 (24%), Positives = 126/367 (34%), Gaps = 72/367 (19%)
Query: 1396 EITDFLCRDKKCIASHLLCDYKPDCSDRSDEAH--CAHYTSTTG--SCN----------- 1440
E +F C+D KCI+ +CD +C D SDE+ C T +G SC
Sbjct: 28 ERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFW 87
Query: 1441 -----FETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSS 1495
+ +G+ C S+D+ G I ++ + DSD
Sbjct: 88 RCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCI-SRQFVCDSDRDC----------LD 136
Query: 1496 GSKEGSVARITTSK-SFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIG 1554
GS E S +T SF + C + W DP + GL + G
Sbjct: 137 GSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQ----G 192
Query: 1555 NKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCE 1614
+ + LS + DG D D S C + C
Sbjct: 193 DSSPCSAFEFHCLSGEC---IHSSWRCDGGPDC----KDKSDEENCAV--------ATCR 237
Query: 1615 ADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNM-EFPCSTDECIPSL 1673
D+F C C+ S +CD DC D SDE+ C LC +F C + ECI
Sbjct: 238 PDEFQCSDG-NCIHGSRQCDREYDCKDMSDEVGCV---NVTLCEGPNKFKCHSGECITLD 293
Query: 1674 LLCDGVPDCHFNEDELI--CSNKSC--SNGAL--VC----------ASSNSCIPAHQRCD 1717
+C+ DC DE I C C +NG VC + A +RC+
Sbjct: 294 KVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCE 353
Query: 1718 GFADCMD 1724
+C D
Sbjct: 354 DIDECQD 360
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/52 (51%), Positives = 33/52 (63%), Gaps = 3/52 (5%)
Query: 72 KLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFC 123
K CS DEF C G+CI+++ VCDS +DC D SDE A+C LTC S C
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE--ASCPV-LTCGPASFQC 155
Score = 48.1 bits (113), Expect = 8e-05
Identities = 22/45 (48%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
PP C+ +EF C DG CI + CD DC D SDEASC + C
Sbjct: 105 PPKTCSQDEFRCH-DGKCISRQFVCDSDRDCLDGSDEASCPVLTC 148
Score = 47.0 bits (110), Expect = 2e-04
Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 13/85 (15%)
Query: 1388 GEISELCPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFET 1443
G + CP T +F C D KCI+ +CD DC D SDEA C T G +F+
Sbjct: 98 GSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCP--VLTCGPASFQC 155
Query: 1444 SSGN-----WTTACSLTQDSEDDLD 1463
+S W AC D ED D
Sbjct: 156 NSSTCIPQLW--ACDNDPDCEDGSD 178
Score = 47.0 bits (110), Expect = 2e-04
Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV-MEVCSFEKRSLC 738
C +EF C SDG+CI ++CD +YDC D SDE CV + +C + C
Sbjct: 236 CRPDEFQC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKC 284
Score = 46.6 bits (109), Expect = 2e-04
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCG 124
C +EF C G+CI+ + VCD +C D SDE TC +TC CG
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS-VTCKSGDFSCG 76
Score = 43.5 bits (101), Expect = 0.002
Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 14/108 (12%)
Query: 1359 EPECPRGRSALLKGPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKP 1418
+P+C G E P R L S C +F C +CI S CD P
Sbjct: 170 DPDCEDGSD--------EWPQRCRGLYVFQGDSSPCSAF-EFHCLSGECIHSSWRCDGGP 220
Query: 1419 DCSDRSDEAHCAHYTSTTGSCNFETSSGN---WTTACSLTQDSEDDLD 1463
DC D+SDE +CA +T F+ S GN + C D +D D
Sbjct: 221 DCKDKSDEENCA--VATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSD 266
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/40 (52%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDED---PATC 110
CSA EF C SG+CI CD DC D+SDE+ ATC
Sbjct: 197 CSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATC 236
Score = 41.2 bits (95), Expect = 0.009
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETT---FICRTSSGRCD 948
P + C+ EF C + CI++ +CD DC D SDE + C +S +C+
Sbjct: 105 PPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCN 156
Score = 41.2 bits (95), Expect = 0.009
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVC 730
C+ EF C S G CI +CD DC DKSDE +C + C
Sbjct: 197 CSAFEFHCLS-GECIHSSWRCDGGPDCKDKSDEENCAVATC 236
Score = 40.0 bits (92), Expect = 0.021
Identities = 16/32 (50%), Positives = 17/32 (53%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C DEF C+ G CI CD DC D SDE
Sbjct: 236 CRPDEFQCSDGNCIHGSRQCDREYDCKDMSDE 267
Score = 40.0 bits (92), Expect = 0.021
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 73 LCSA-DEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESG 121
LC ++F C SG+CI + VC+ +DC D SDE C + D G
Sbjct: 275 LCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGG 324
Score = 38.5 bits (88), Expect = 0.060
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Query: 1129 ECHNGKCYRLEQSCNFVDNCGDNTDE--NECGSS-CTFEKGWC 1168
+CH+G+C L++ CN +C D +DE ECG++ C G C
Sbjct: 283 KCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGC 325
Score = 38.1 bits (87), Expect = 0.079
Identities = 16/37 (43%), Positives = 18/37 (48%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATC 110
C F C S CI + CD+ DC D SDE P C
Sbjct: 148 CGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRC 184
Score = 36.2 bits (82), Expect = 0.30
Identities = 15/37 (40%), Positives = 21/37 (56%)
Query: 907 HEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTS 943
++F C + CI DK+C+ DC D SDE C T+
Sbjct: 280 NKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTN 316
Score = 35.8 bits (81), Expect = 0.39
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 13/76 (17%)
Query: 459 PAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC------APELQCNFETGI- 511
P ++C D F C H CI + +CD DC D +DE +C QCN T I
Sbjct: 105 PPKTCSQ-DEFRC-HDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIP 162
Query: 512 ----CNWEQDAKDDFD 523
C+ + D +D D
Sbjct: 163 QLWACDNDPDCEDGSD 178
Score = 35.4 bits (80), Expect = 0.51
Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 903 KCTDHEFMCANKHCIAKDKLCDFVNDCADNSDET-----TFICRTSSGRCDFEFDLC--- 954
+C +EF C + CI+ +CD +C D SDE+ + C++ C + C
Sbjct: 26 RCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQ 85
Query: 955 SWKQEKDEDFD 965
W+ + D D
Sbjct: 86 FWRCDGQVDCD 96
Score = 35.4 bits (80), Expect = 0.51
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 6/55 (10%)
Query: 678 ETSVPVTLPPHNCTDNEFICRSD-GHCIEKMQKCDFKYDCPDKSDEASCVMEVCS 731
ET + VT C +F C CI + +CD + DC + SDE C + CS
Sbjct: 61 ETCLSVT-----CKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCS 110
Score = 35.0 bits (79), Expect = 0.67
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA--SCVMEVC 730
C NEF C+ DG CI CD +C D SDE+ +C+ C
Sbjct: 27 CERNEFQCQ-DGKCISYKWVCDGSAECQDGSDESQETCLSVTC 68
Score = 34.3 bits (77), Expect = 1.1
Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 4/37 (10%)
Query: 1394 CPEIT----DFLCRDKKCIASHLLCDYKPDCSDRSDE 1426
CP +T F C CI CD PDC D SDE
Sbjct: 143 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDE 179
Score = 34.3 bits (77), Expect = 1.1
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C EF C++ +CI + CD DC D SDE
Sbjct: 236 CRPDEFQCSDGNCIHGSRQCDREYDCKDMSDE 267
Score = 33.1 bits (74), Expect = 2.5
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 3/47 (6%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE---TTFICRTSSGRC 947
C+ EF C + CI CD DC D SDE CR +C
Sbjct: 197 CSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQC 243
Score = 33.1 bits (74), Expect = 2.5
Identities = 22/58 (37%), Positives = 26/58 (44%), Gaps = 11/58 (18%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNCA------PELQCNFETGI-----CNWEQDAKDDFD 523
CI CD DC D++DE NCA E QC+ I C+ E D KD D
Sbjct: 209 CIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSD 266
Score = 33.1 bits (74), Expect = 2.5
Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 24/107 (22%)
Query: 452 ENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFET-- 509
ENC + +C D F C CI R CD DC D +DEV C C
Sbjct: 229 ENCAVA----TCRP-DEFQCSDGN-CIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKF 282
Query: 510 -----------GICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLG 545
+CN +D + DW S P T DN G
Sbjct: 283 KCHSGECITLDKVCNMARDCR---DW--SDEPIKECGTNECLDNNGG 324
Score = 32.3 bits (72), Expect = 4.3
Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 8/97 (8%)
Query: 1389 EISELCPEIT----DFLC--RDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFE 1442
E E C +T DF C R +CI CD + DC + SDE C T F
Sbjct: 58 ESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCP--PKTCSQDEFR 115
Query: 1443 TSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDS 1479
G + + D LD + + P P S
Sbjct: 116 CHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPAS 152
Score = 31.6 bits (70), Expect = 7.4
Identities = 16/42 (38%), Positives = 18/42 (42%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICR 941
P C F C + CI + CD DC D SDE CR
Sbjct: 144 PVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCR 185
Score = 31.2 bits (69), Expect = 9.6
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 74 CSADEFPCTS--GQCIAKESVCDSRQDCSDESDED---PATCSK 112
C + +F C +CI + CD + DC + SDE P TCS+
Sbjct: 68 CKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQ 111
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 82.8 bits (203), Expect = 3e-15
Identities = 139/612 (22%), Positives = 217/612 (35%), Gaps = 138/612 (22%)
Query: 504 QCNFETG---ICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQ 560
QC+FE +C+W Q + DD DW R+ GP+PT +TG G +G YL++ES+
Sbjct: 40 QCDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGSTGAPGGYPNG--EGSYLHMESNSFH 97
Query: 561 AFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQ---LLWQIFG 617
A LLSP L + F +HMFG + + + S G+ +LW+ +
Sbjct: 98 R-GGVARLLSPDL--WEQGPLCVHFAHHMFGLS-WGAQLRLLLLSGEEGRRPDVLWKHWN 153
Query: 618 NQGNRWIRKHLNISS--RQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPT 675
Q W+ + + + P +++ E + G DIA+D LS
Sbjct: 154 TQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALS----------------- 196
Query: 676 PPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKR 735
I R + + MQ C F D P+
Sbjct: 197 --------------------IRRGSCNRVCMMQTCSF--DIPN----------------- 217
Query: 736 SLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNG 795
LC W + ++ +W G S G+ P D + + G Y+ D N
Sbjct: 218 DLCDW------TWIPTASGAKWTQKKGSS---GKPGVGPDGDFS-SPGSGCYMLLDPKNA 267
Query: 796 KFGDTADILTPIISLTGPKCTLVFWTHMNGATVG-SLQVLIKKDNVTSKLWAQTGQQGAQ 854
+ G A +L+P +SL+ + F + G + G +L + K +GQ G
Sbjct: 268 RPGQKAVLLSP-VSLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPN 326
Query: 855 WKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANK 914
W+ V Q G + VAVD S C
Sbjct: 327 WQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDATSIAPCG------------------- 367
Query: 915 HCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE---FDLCSWKQEKDEDFDWNLKAS 971
+CDFE C W Q + W L
Sbjct: 368 ---------------------------EGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHK 400
Query: 972 SIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFHYHMY 1031
+ P G PA N+ GHYI++++ Q ++ R+ S C + F YHMY
Sbjct: 401 NGPVHGMGPAGG--FPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGDIC-VEFAYHMY 457
Query: 1032 GNGIGA-LTLMQVSVTNQTKVLLNLTV-EQGNFWRREELSLFG--DEDFQLKFEGRVGKG 1087
G G G L L+ S + L V Q +W+ +++ + QL F+G G
Sbjct: 458 GLGEGTMLELLLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSN 517
Query: 1088 QRGDIALDDIVL 1099
+A+ I++
Sbjct: 518 TASVVAMGFILI 529
Score = 63.2 bits (152), Expect = 2e-09
Identities = 133/595 (22%), Positives = 215/595 (36%), Gaps = 106/595 (17%)
Query: 116 CDFESG---FCGWEPFLTEDSHWKLMKGLN-NGEHHFPAADHTANINHGSFIYLEAQ--R 169
CDFE C W +D W G + G P GS++++E+
Sbjct: 41 CDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGSTGAPGGYPNGE---GSYLHMESNSFH 97
Query: 170 SPGVAKLGSPVLTKLLTASTPCQVQFWYH---LSQHSNLSVFTRTSLDGNLQKQGKIIRF 226
GVA+L SP L + P V F +H LS + L + + +G ++ + +
Sbjct: 98 RGGVARLLSPDLWE----QGPLCVHFAHHMFGLSWGAQLRLLLLSGEEG--RRPDVLWKH 151
Query: 227 SESQWSHAKIDLIAEAGESTLPFQLILEATVLSSN-ATVALDDISVSQECEISYKSLPRT 285
+Q + + TLP +L+ E T S+ +ALD +S+ + S R
Sbjct: 152 WNTQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRG------SCNRV 205
Query: 286 STQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFM 345
S D + CDW + W +Q + S+ P D S S G +M
Sbjct: 206 CMMQTCS-FDIPNDLCDWTWIPTASGAKW---TQKKGSSGKPGVGPDGDFSSPGS-GCYM 260
Query: 346 FILKKSSSLWQVAKLQSPTFSQTGPGCI-LSFWFYNYGLSVGAAELQLHMENSHDSTVIW 404
+ K++ Q A L SP GC+ SF + G S GAA LH+ S ++
Sbjct: 261 LLDPKNARPGQKAVLLSPV--SLSSGCLSFSFHYILRGQSPGAA---LHIYASVLGSIRK 315
Query: 405 RVLYN--QGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAES 462
L++ G W ++ + + + +G++ P PA +
Sbjct: 316 HTLFSGQPGPNWQAVSVNYTAVGR-----IQFAVVGVFGKT-------------PEPAVA 357
Query: 463 CEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETG---ICNWEQDAK 519
+ + CG+ QC+FE C+W Q +
Sbjct: 358 VDATS-------------------IAPCGEGFP--------QCDFEDNAHPFCDWVQTSG 390
Query: 520 DDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSE-PQAFQDSAALLSPILNATDT 578
D W P GP A GHY+Y+E+ E QA Q + P D
Sbjct: 391 DGGHWALGHKNGPVHGMGPA--GGFPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGD- 447
Query: 579 KGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQ---LLWQIFGNQGNRWIRKHLNISS--R 633
F YHM+G + + + + G LW+ G+Q W + + S +
Sbjct: 448 --ICVEFAYHMYG--LGEGTMLELLLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQ 503
Query: 634 QPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADL--PTPPETSVPVTLP 686
QP Q++ + G +A+ + + PG P + PP + V T P
Sbjct: 504 QPMQLIFKGIQGSNTASVVAMGFI-----LINPGTCPVKVLPELPPVSPVSSTGP 553
Score = 51.6 bits (122), Expect = 7e-06
Identities = 87/385 (22%), Positives = 141/385 (36%), Gaps = 63/385 (16%)
Query: 719 KSDEASCVMEVCSFEK--RSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSV 776
+S + V+ C FE + LC W Q + D + G + G P+
Sbjct: 30 RSSRDNYVLTQCDFEDDAKPLCDWSQ-----VSADDEDWVRASGPSPTGSTGAPGGYPN- 83
Query: 777 DHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGS-LQVLI 835
+G YL+ +S++ G A +L+P + GP C + F HM G + G+ L++L+
Sbjct: 84 ------GEGSYLHMESNSFHRGGVARLLSPDLWEQGPLC-VHFAHHMFGLSWGAQLRLLL 136
Query: 836 ---KKDNVTSKLWAQTGQQGAQWKRAEVFL--GIRSHTQIVFRAKRGISYIGDVAVDDIS 890
++ LW Q W V + G T+++F RG + D+A+D +S
Sbjct: 137 LSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALS 196
Query: 891 FQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE 950
+ S N+ C+ + D ND D T+I S +
Sbjct: 197 IRRGS----------------CNRVCMMQTCSFDIPNDLCD----WTWIPTASGAK---- 232
Query: 951 FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARI 1010
W K S G P D + SG Y+ + +P + A +
Sbjct: 233 ---------------WTQKKGSSGKPGVGPDGDFS-SPGSGCYMLLDPK-NARPGQKAVL 275
Query: 1011 SSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSL 1070
SPV S S FHY + G GA + SV + + + G W+ ++
Sbjct: 276 LSPV-SLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNY 334
Query: 1071 FGDEDFQLKFEGRVGKGQRGDIALD 1095
Q G GK +A+D
Sbjct: 335 TAVGRIQFAVVGVFGKTPEPAVAVD 359
Score = 47.8 bits (112), Expect = 1e-04
Identities = 54/224 (24%), Positives = 89/224 (39%), Gaps = 13/224 (5%)
Query: 946 RCDFEFD---LCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQ 1002
+CDFE D LC W Q +D DW + P T A N G Y+ ++S
Sbjct: 40 QCDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGST--GAPGGYPNGEGSYLHMESNSFH 97
Query: 1003 QPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGA---LTLMQVSVTNQTKVLLNLTVEQ 1059
+ AR+ SP + ++ C + F +HM+G GA L L+ + VL Q
Sbjct: 98 RG-GVARLLSPDLWEQGPLC-VHFAHHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQ 155
Query: 1060 GNFWRREELSLFGDEDF--QLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVP 1117
W +++ +L FEG G DIALD + + + + + +
Sbjct: 156 RPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRGSCN-RVCMMQTCSFD 214
Query: 1118 LPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSC 1161
+P C + +G + ++ + G + D + GS C
Sbjct: 215 IPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFSSPGSGC 258
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 82.8 bits (203), Expect = 3e-15
Identities = 139/612 (22%), Positives = 217/612 (35%), Gaps = 138/612 (22%)
Query: 504 QCNFETG---ICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQ 560
QC+FE +C+W Q + DD DW R+ GP+PT +TG G +G YL++ES+
Sbjct: 40 QCDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGSTGAPGGYPNG--EGSYLHMESNSFH 97
Query: 561 AFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQ---LLWQIFG 617
A LLSP L + F +HMFG + + + S G+ +LW+ +
Sbjct: 98 R-GGVARLLSPDL--WEQGPLCVHFAHHMFGLS-WGAQLRLLLLSGEEGRRPDVLWKHWN 153
Query: 618 NQGNRWIRKHLNISS--RQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPT 675
Q W+ + + + P +++ E + G DIA+D LS
Sbjct: 154 TQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALS----------------- 196
Query: 676 PPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKR 735
I R + + MQ C F D P+
Sbjct: 197 --------------------IRRGSCNRVCMMQTCSF--DIPN----------------- 217
Query: 736 SLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNG 795
LC W + ++ +W G S G+ P D + + G Y+ D N
Sbjct: 218 DLCDW------TWIPTASGAKWTQKKGSS---GKPGVGPDGDFS-SPGSGCYMLLDPKNA 267
Query: 796 KFGDTADILTPIISLTGPKCTLVFWTHMNGATVG-SLQVLIKKDNVTSKLWAQTGQQGAQ 854
+ G A +L+P +SL+ + F + G + G +L + K +GQ G
Sbjct: 268 RPGQKAVLLSP-VSLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPN 326
Query: 855 WKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANK 914
W+ V Q G + VAVD S C
Sbjct: 327 WQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDATSIAPCG------------------- 367
Query: 915 HCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE---FDLCSWKQEKDEDFDWNLKAS 971
+CDFE C W Q + W L
Sbjct: 368 ---------------------------EGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHK 400
Query: 972 SIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFHYHMY 1031
+ P G PA N+ GHYI++++ Q ++ R+ S C + F YHMY
Sbjct: 401 NGPVHGMGPAGG--FPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGDIC-VEFAYHMY 457
Query: 1032 GNGIGA-LTLMQVSVTNQTKVLLNLTV-EQGNFWRREELSLFG--DEDFQLKFEGRVGKG 1087
G G G L L+ S + L V Q +W+ +++ + QL F+G G
Sbjct: 458 GLGEGTMLELLLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSN 517
Query: 1088 QRGDIALDDIVL 1099
+A+ I++
Sbjct: 518 TASVVAMGFILI 529
Score = 63.2 bits (152), Expect = 2e-09
Identities = 133/595 (22%), Positives = 215/595 (36%), Gaps = 106/595 (17%)
Query: 116 CDFESG---FCGWEPFLTEDSHWKLMKGLN-NGEHHFPAADHTANINHGSFIYLEAQ--R 169
CDFE C W +D W G + G P GS++++E+
Sbjct: 41 CDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGSTGAPGGYPNGE---GSYLHMESNSFH 97
Query: 170 SPGVAKLGSPVLTKLLTASTPCQVQFWYH---LSQHSNLSVFTRTSLDGNLQKQGKIIRF 226
GVA+L SP L + P V F +H LS + L + + +G ++ + +
Sbjct: 98 RGGVARLLSPDLWE----QGPLCVHFAHHMFGLSWGAQLRLLLLSGEEG--RRPDVLWKH 151
Query: 227 SESQWSHAKIDLIAEAGESTLPFQLILEATVLSSN-ATVALDDISVSQECEISYKSLPRT 285
+Q + + TLP +L+ E T S+ +ALD +S+ + S R
Sbjct: 152 WNTQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRG------SCNRV 205
Query: 286 STQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFM 345
S D + CDW + W +Q + S+ P D S S G +M
Sbjct: 206 CMMQTCS-FDIPNDLCDWTWIPTASGAKW---TQKKGSSGKPGVGPDGDFSSPGS-GCYM 260
Query: 346 FILKKSSSLWQVAKLQSPTFSQTGPGCI-LSFWFYNYGLSVGAAELQLHMENSHDSTVIW 404
+ K++ Q A L SP GC+ SF + G S GAA LH+ S ++
Sbjct: 261 LLDPKNARPGQKAVLLSPV--SLSSGCLSFSFHYILRGQSPGAA---LHIYASVLGSIRK 315
Query: 405 RVLYN--QGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAES 462
L++ G W ++ + + + +G++ P PA +
Sbjct: 316 HTLFSGQPGPNWQAVSVNYTAVGR-----IQFAVVGVFGKT-------------PEPAVA 357
Query: 463 CEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETG---ICNWEQDAK 519
+ + CG+ QC+FE C+W Q +
Sbjct: 358 VDATS-------------------IAPCGEGFP--------QCDFEDNAHPFCDWVQTSG 390
Query: 520 DDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSE-PQAFQDSAALLSPILNATDT 578
D W P GP A GHY+Y+E+ E QA Q + P D
Sbjct: 391 DGGHWALGHKNGPVHGMGPA--GGFPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGD- 447
Query: 579 KGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQ---LLWQIFGNQGNRWIRKHLNISS--R 633
F YHM+G + + + + G LW+ G+Q W + + S +
Sbjct: 448 --ICVEFAYHMYG--LGEGTMLELLLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQ 503
Query: 634 QPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADL--PTPPETSVPVTLP 686
QP Q++ + G +A+ + + PG P + PP + V T P
Sbjct: 504 QPMQLIFKGIQGSNTASVVAMGFI-----LINPGTCPVKVLPELPPVSPVSSTGP 553
Score = 51.6 bits (122), Expect = 7e-06
Identities = 87/385 (22%), Positives = 141/385 (36%), Gaps = 63/385 (16%)
Query: 719 KSDEASCVMEVCSFEK--RSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSV 776
+S + V+ C FE + LC W Q + D + G + G P+
Sbjct: 30 RSSRDNYVLTQCDFEDDAKPLCDWSQ-----VSADDEDWVRASGPSPTGSTGAPGGYPN- 83
Query: 777 DHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGS-LQVLI 835
+G YL+ +S++ G A +L+P + GP C + F HM G + G+ L++L+
Sbjct: 84 ------GEGSYLHMESNSFHRGGVARLLSPDLWEQGPLC-VHFAHHMFGLSWGAQLRLLL 136
Query: 836 ---KKDNVTSKLWAQTGQQGAQWKRAEVFL--GIRSHTQIVFRAKRGISYIGDVAVDDIS 890
++ LW Q W V + G T+++F RG + D+A+D +S
Sbjct: 137 LSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALS 196
Query: 891 FQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFE 950
+ S N+ C+ + D ND D T+I S +
Sbjct: 197 IRRGS----------------CNRVCMMQTCSFDIPNDLCD----WTWIPTASGAK---- 232
Query: 951 FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARI 1010
W K S G P D + SG Y+ + +P + A +
Sbjct: 233 ---------------WTQKKGSSGKPGVGPDGDFS-SPGSGCYMLLDPK-NARPGQKAVL 275
Query: 1011 SSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSL 1070
SPV S S FHY + G GA + SV + + + G W+ ++
Sbjct: 276 LSPV-SLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNY 334
Query: 1071 FGDEDFQLKFEGRVGKGQRGDIALD 1095
Q G GK +A+D
Sbjct: 335 TAVGRIQFAVVGVFGKTPEPAVAVD 359
Score = 47.8 bits (112), Expect = 1e-04
Identities = 54/224 (24%), Positives = 89/224 (39%), Gaps = 13/224 (5%)
Query: 946 RCDFEFD---LCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQ 1002
+CDFE D LC W Q +D DW + P T A N G Y+ ++S
Sbjct: 40 QCDFEDDAKPLCDWSQVSADDEDWVRASGPSPTGST--GAPGGYPNGEGSYLHMESNSFH 97
Query: 1003 QPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGA---LTLMQVSVTNQTKVLLNLTVEQ 1059
+ AR+ SP + ++ C + F +HM+G GA L L+ + VL Q
Sbjct: 98 RG-GVARLLSPDLWEQGPLC-VHFAHHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQ 155
Query: 1060 GNFWRREELSLFGDEDF--QLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVP 1117
W +++ +L FEG G DIALD + + + + + +
Sbjct: 156 RPSWMLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRGSCN-RVCMMQTCSFD 214
Query: 1118 LPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSC 1161
+P C + +G + ++ + G + D + GS C
Sbjct: 215 IPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFSSPGSGC 258
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 82.4 bits (202), Expect = 4e-15
Identities = 46/120 (38%), Positives = 54/120 (45%), Gaps = 9/120 (7%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C + C CVP CD +DC DGSDE C P C + CS+ C+P
Sbjct: 1376 CAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGC----AAPGCGEGQMTCSSGHCLPL 1431
Query: 1673 LLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
LLCD DC DE + C G L CA C+P CDG DC+D DE SC
Sbjct: 1432 ALLCDRQDDCGDGTDE---PSYPCPQGLLACADGR-CLPPALLCDGHPDCLD-AADEESC 1486
Score = 72.8 bits (177), Expect = 3e-12
Identities = 42/113 (37%), Positives = 55/113 (48%), Gaps = 10/113 (8%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C Q +C + C+PL+ CD +DC DG+DE P C C+ C+P
Sbjct: 1416 CGEGQMTCS-SGHCLPLALLCDRQDDCGDGTDEPSYP-------CPQGLLACADGRCLPP 1467
Query: 1673 LLLCDGVPDCHFNEDELICSNK-SCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
LLCDG PDC DE C + +C G + C +C+ A Q CDG DC D
Sbjct: 1468 ALLCDGHPDCLDAADEESCLGQVTCVPGEVSCV-DGTCLGAIQLCDGVWDCPD 1519
Score = 63.2 bits (152), Expect = 2e-09
Identities = 48/152 (31%), Positives = 56/152 (36%), Gaps = 43/152 (28%)
Query: 1615 ADQFSCIYTLQCVP-----LSGKC-------DGHEDCIDGSDEMD--CPLS--PTPPL-- 1656
AD+ SC+ + CVP + G C DG DC DG+DE CPL PTPP
Sbjct: 1481 ADEESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPAST 1540
Query: 1657 ------------------------CSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICS 1692
C EF C + EC P CD DC DE C
Sbjct: 1541 LPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCG 1600
Query: 1693 NKSCSNGALVCASSNSCIPAHQRCDGFADCMD 1724
C+ CA C+ Q CDG C D
Sbjct: 1601 G-PCAPHHAPCARGPHCVSPEQLCDGVRQCPD 1631
Score = 61.6 bits (148), Expect = 7e-09
Identities = 54/166 (32%), Positives = 67/166 (40%), Gaps = 35/166 (21%)
Query: 1597 TPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCP------L 1650
TP + P P P C Q C L CV + CDG EDC+DGSDE C L
Sbjct: 2375 TPAGQSVAPGPFPPVQCGPGQTPC-EVLGCVEQAQVCDGREDCLDGSDERHCARNLLMWL 2433
Query: 1651 SPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCI 1710
P L + P +P++ L G+P S CS L C S C+
Sbjct: 2434 PSLPALWAASTVPFM----MPTMAL-PGLP----------ASRALCSPSQLSCGSGE-CL 2477
Query: 1711 PAHQRCDGFADCMDFQLDESSCSD----TWTL-------LGIGLAF 1745
A +RCD DC D DE C D W++ G+GL F
Sbjct: 2478 SAERRCDLRPDCQDGS-DEDGCVDCVLAPWSVWSSCSRSCGLGLTF 2522
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/130 (32%), Positives = 51/130 (39%), Gaps = 33/130 (25%)
Query: 1612 PCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCST-DECI 1670
PC +F C + +C P +CD EDC DGSDE C P C+ PC+ C+
Sbjct: 1564 PCGPFEFRC-GSGECTPRGWRCDQEEDCADGSDERGCG-GP----CAPHHAPCARGPHCV 1617
Query: 1671 PSLLLCDGVPDCHFNEDE------------------LICSNKSCSNGALVCASSNSCIPA 1712
LCDGV C DE L C +C NG +CI
Sbjct: 1618 SPEQLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNG--------TCIGF 1669
Query: 1713 HQRCDGFADC 1722
CDG DC
Sbjct: 1670 QLVCDGQPDC 1679
Score = 49.3 bits (116), Expect = 3e-05
Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 1655 PLCSNMEFPCSTD-ECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAH 1713
P C+ E C + C+P LCD DC DE C+ C G + C SS C+P
Sbjct: 1374 PACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTC-SSGHCLPLA 1432
Query: 1714 QRCDGFADCMD 1724
CD DC D
Sbjct: 1433 LLCDRQDDCGD 1443
Score = 48.9 bits (115), Expect = 4e-05
Identities = 21/41 (51%), Positives = 25/41 (60%)
Query: 66 GQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDED 106
G SR LCS + C SG+C++ E CD R DC D SDED
Sbjct: 2456 GLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDED 2496
Score = 46.6 bits (109), Expect = 2e-04
Identities = 29/91 (31%), Positives = 32/91 (35%), Gaps = 7/91 (7%)
Query: 1599 ECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPL-- 1656
+C G PC C CV CDG C DGSDE P L
Sbjct: 1589 DCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGG 1648
Query: 1657 -----CSNMEFPCSTDECIPSLLLCDGVPDC 1682
E+ C CI L+CDG PDC
Sbjct: 1649 PNRTGLPCPEYTCPNGTCIGFQLVCDGQPDC 1679
Score = 45.8 bits (107), Expect = 4e-04
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLL 749
C + E +C+ +GHC+ CD + DC D SDE C C E + C +P+ LL
Sbjct: 1376 CAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG-EGQMTCSSGHCLPLALL 1434
Query: 750 QD 751
D
Sbjct: 1435 CD 1436
Score = 44.3 bits (103), Expect = 0.001
Identities = 43/138 (31%), Positives = 48/138 (34%), Gaps = 5/138 (3%)
Query: 1389 EISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC-AHYTSTTG--SCNFETSS 1445
E S CP+ C D +C+ LLCD PDC D +DE C T G SC T
Sbjct: 1447 EPSYPCPQGL-LACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCVDGTCL 1505
Query: 1446 GNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARI 1505
G C D D D G P + PG L SS S A
Sbjct: 1506 GA-IQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPP 1564
Query: 1506 TTSKSFPASLGMCTVRFW 1523
F G CT R W
Sbjct: 1565 CGPFEFRCGSGECTPRGW 1582
Score = 42.0 bits (97), Expect = 0.005
Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 19/96 (19%)
Query: 660 MDCTLYPGNLPADLPTPPETSVPVT----------LPPHNCTDNEFICRSDGHCIEKMQK 709
M+ P + A PP P T PP C + C G C+E+ Q
Sbjct: 2351 MEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG-CVEQAQV 2409
Query: 710 CDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIP 745
CD + DC D SDE C R+L W +P
Sbjct: 2410 CDGREDCLDGSDERHCA--------RNLLMWLPSLP 2437
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 45 EGTLLSQRSFIALDHLWVYA----CGQTQSRKLCSAD-----EFPCTSGQCIAKESVCDS 95
EG L Q + + H W+ CG + C+A + C+SG C+ +CD
Sbjct: 1378 EGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDR 1437
Query: 96 RQDCSDESDEDPATCSKHL 114
+ DC D +DE C + L
Sbjct: 1438 QDDCGDGTDEPSYPCPQGL 1456
Score = 40.0 bits (92), Expect = 0.021
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 17/76 (22%)
Query: 666 PGNLPA-DLPTPPETSVP---------------VTLPPHNCTDNEFICRSDGHCIEKMQK 709
PG+ P LPTPP +++P P C EF C S G C + +
Sbjct: 1525 PGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPPCGPFEFRCGS-GECTPRGWR 1583
Query: 710 CDFKYDCPDKSDEASC 725
CD + DC D SDE C
Sbjct: 1584 CDQEEDCADGSDERGC 1599
Score = 38.9 bits (89), Expect = 0.046
Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFIC-----RTSSGRC 947
C + + C++ HC+ LCD +DC D +DE ++ C + GRC
Sbjct: 1416 CGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRC 1464
Score = 38.1 bits (87), Expect = 0.079
Identities = 18/43 (41%), Positives = 22/43 (51%)
Query: 1649 PLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELIC 1691
P SP PLC + C++ EC+ CDGV DC DE C
Sbjct: 2226 PGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGC 2268
Score = 37.7 bits (86), Expect = 0.10
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C EF C SG+C + CD +DC+D SDE
Sbjct: 1565 CGPFEFRCGSGECTPRGWRCDQEEDCADGSDE 1596
Score = 37.7 bits (86), Expect = 0.10
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 74 CSADEFPCTSG-QCIAKESVCDSRQDCSDESDEDPATC 110
C+ PC G C++ E +CD + C D SDE P C
Sbjct: 1603 CAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDAC 1640
Score = 37.7 bits (86), Expect = 0.10
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 904 CTDHEFMCAN-KHCIAKDKLCDFVNDCADNSDETTFIC 940
C H CA HC++ ++LCD V C D SDE C
Sbjct: 1603 CAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDAC 1640
Score = 37.0 bits (84), Expect = 0.18
Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 23/122 (18%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTC-----DFESGFCGWEPF 128
C C G+C+ +CD DC D +DE+ +C +TC G C
Sbjct: 1452 CPQGLLACADGRCLPPALLCDGHPDCLDAADEE--SCLGQVTCVPGEVSCVDGTCLGAIQ 1509
Query: 129 LTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPVLTKLLTAS 188
L D W G + G H P L + +P + L P L TAS
Sbjct: 1510 LC-DGVWDCPDGADEGPGHCP---------------LPSLPTPPASTLPGPSPGSLDTAS 1553
Query: 189 TP 190
+P
Sbjct: 1554 SP 1555
Score = 37.0 bits (84), Expect = 0.18
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 895 SPLLS--PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
SPL S P C EF C + C + CD DCAD SDE
Sbjct: 1554 SPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDE 1596
Score = 37.0 bits (84), Expect = 0.18
Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 6/54 (11%)
Query: 1600 CVTGGPVPVQPSP-CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSP 1652
C G P P+P C C + +CV G CDG DC DGSDE C L P
Sbjct: 2224 CEPGSP----PAPLCPGVGLRCA-SGECVLRGGPCDGVLDCEDGSDEEGCVLLP 2272
Score = 37.0 bits (84), Expect = 0.18
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL 114
C + PC C+ + VCD R+DC D SDE C+++L
Sbjct: 2391 CGPGQTPCEVLGCVEQAQVCDGREDCLDGSDE--RHCARNL 2429
Score = 37.0 bits (84), Expect = 0.18
Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
C+ ++ C S G C+ ++CD + DC D SDE CV
Sbjct: 2464 CSPSQLSCGS-GECLSAERRCDLRPDCQDGSDEDGCV 2499
Score = 37.0 bits (84), Expect = 0.18
Identities = 35/126 (27%), Positives = 48/126 (38%), Gaps = 27/126 (21%)
Query: 1599 ECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCS 1658
E GGP P CEA ++TL C + +C C D D + C P P C
Sbjct: 4657 ESCNGGPCP----ECEAQD--TVFTLDC---ANQCP--HSCADLWDRVQCLQGPCRPGCR 4705
Query: 1659 NMEFPCSTD-ECIPSLLLCDGVPDCHFNED-------ELICSNKSCSNGALVCASSNSCI 1710
D C+P G+P + + + +L C N +C N +LVC
Sbjct: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVC------- 4758
Query: 1711 PAHQRC 1716
HQ C
Sbjct: 4759 -PHQEC 4763
Score = 35.8 bits (81), Expect = 0.39
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1358 PEPECPRGRSALLKGPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYK 1417
P P P ++ L GP + S+ L+ + C +F C +C CD +
Sbjct: 1529 PLPSLPTPPASTLPGPSPGSLDTASSPLASASPAPPCGPF-EFRCGSGECTPRGWRCDQE 1587
Query: 1418 PDCSDRSDEAHC 1429
DC+D SDE C
Sbjct: 1588 EDCADGSDERGC 1599
Score = 35.8 bits (81), Expect = 0.39
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 883 DVAVDDISFQ----DCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
DV D+ Q C P P C CA+ C+ + CD V DC D SDE
Sbjct: 2209 DVHHSDVPLQVELLGCEPGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDE 2265
Score = 35.8 bits (81), Expect = 0.39
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 73 LCSADEFPCTSGQCIAKESVCDSRQDCSDESDED 106
LC C SG+C+ + CD DC D SDE+
Sbjct: 2233 LCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEE 2266
Score = 35.0 bits (79), Expect = 0.67
Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
Query: 904 CTDHEFMCA-NKHCIAKDKLCDFVNDCADNSDE 935
C + E +C N HC+ LCD +DC D SDE
Sbjct: 1376 CAEGEALCQENGHCVPHGWLCDNQDDCGDGSDE 1408
Score = 34.7 bits (78), Expect = 0.87
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 1388 GEISELCPEITD--FLCRDK-KCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETS 1444
G EL P + LC++ C+ LCD + DC D SDE CA G S
Sbjct: 1367 GHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCA--APGCGEGQMTCS 1424
Query: 1445 SGNWTTACSLTQDSEDD 1461
SG+ +L D +DD
Sbjct: 1425 SGH-CLPLALLCDRQDD 1440
Score = 34.3 bits (77), Expect = 1.1
Identities = 14/30 (46%), Positives = 17/30 (56%)
Query: 471 CRHTRACIEKLRLCDLVDDCGDRTDEVNCA 500
C+ C+ LCD DDCGD +DE CA
Sbjct: 1383 CQENGHCVPHGWLCDNQDDCGDGSDEEGCA 1412
Score = 34.3 bits (77), Expect = 1.1
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 686 PPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEV 729
P + C C +DG C+ CD DC D +DE SC+ +V
Sbjct: 1448 PSYPCPQGLLAC-ADGRCLPPALLCDGHPDCLDAADEESCLGQV 1490
Score = 34.3 bits (77), Expect = 1.1
Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE 722
C E C DG C+ +Q CD +DCPD +DE
Sbjct: 1492 CVPGEVSC-VDGTCLGAIQLCDGVWDCPDGADE 1523
Score = 34.3 bits (77), Expect = 1.1
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 1108 DSVQEELAVPLPTGFC-PLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSC 1161
D+ LA P C P +R C +G+C C+ ++C D +DE CG C
Sbjct: 1550 DTASSPLASASPAPPCGPFEFR-CGSGECTPRGWRCDQEEDCADGSDERGCGGPC 1603
Score = 34.3 bits (77), Expect = 1.1
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 1402 CRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
C +C+++ CD +PDC D SDE C
Sbjct: 2471 CGSGECLSAERRCDLRPDCQDGSDEDGC 2498
Score = 33.5 bits (75), Expect = 1.9
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDE 1154
C G C +G C L C+ D+CGD TDE
Sbjct: 1416 CGEGQMTCSSGHCLPLALLCDRQDDCGDGTDE 1447
Score = 33.5 bits (75), Expect = 1.9
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 1402 CRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
C C+ +CD + DC D SDE HCA
Sbjct: 2398 CEVLGCVEQAQVCDGREDCLDGSDERHCA 2426
Score = 33.5 bits (75), Expect = 1.9
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Query: 1116 VPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQA 1175
+P C C +G+C E+ C+ +C D +DE+ C C W W +S +
Sbjct: 2457 LPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGC-VDCVLAP-WSVW-SSCS 2513
Query: 1176 DNFDWVLGVGSHQSLRPP 1193
+ L + LRPP
Sbjct: 2514 RSCGLGLTFQRQELLRPP 2531
Score = 33.5 bits (75), Expect = 1.9
Identities = 11/32 (34%), Positives = 18/32 (56%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C+ + C + C++ ++ CD DC D SDE
Sbjct: 2464 CSPSQLSCGSGECLSAERRCDLRPDCQDGSDE 2495
Score = 32.0 bits (71), Expect = 5.6
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
C E C + C+ +LCD V DC D +DE
Sbjct: 1492 CVPGEVSCVDGTCLGAIQLCDGVWDCPDGADE 1523
Score = 32.0 bits (71), Expect = 5.6
Identities = 13/33 (39%), Positives = 15/33 (45%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDE 722
C + C HC+ Q CD CPD SDE
Sbjct: 1603 CAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDE 1635
Score = 31.6 bits (70), Expect = 7.4
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEAS 724
C + + C S GHC+ CD + DC D +DE S
Sbjct: 1416 CGEGQMTC-SSGHCLPLALLCDRQDDCGDGTDEPS 1449
Score = 31.6 bits (70), Expect = 7.4
Identities = 22/92 (23%), Positives = 34/92 (36%), Gaps = 9/92 (9%)
Query: 900 PERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTS---------SGRCDFE 950
P C CA+ C+ LCD DC D +DE + + + + G C
Sbjct: 1448 PSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCVDGTCLGA 1507
Query: 951 FDLCSWKQEKDEDFDWNLKASSIPAAGTEPAA 982
LC + + D +P+ T PA+
Sbjct: 1508 IQLCDGVWDCPDGADEGPGHCPLPSLPTPPAS 1539
Score = 31.2 bits (69), Expect = 9.6
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 682 PVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVM 727
P + P C C S G C+ + CD DC D SDE CV+
Sbjct: 2226 PGSPPAPLCPGVGLRCAS-GECVLRGGPCDGVLDCEDGSDEEGCVL 2270
Score = 31.2 bits (69), Expect = 9.6
Identities = 12/27 (44%), Positives = 19/27 (70%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNCAPEL 503
C+E+ ++CD +DC D +DE +CA L
Sbjct: 2403 CVEQAQVCDGREDCLDGSDERHCARNL 2429
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 80.9 bits (198), Expect = 1e-14
Identities = 47/121 (38%), Positives = 62/121 (51%), Gaps = 11/121 (9%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C + F C +T +C+ S CDG++DC D SDE +C +PT E C CI
Sbjct: 306 CSENLFHC-HTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPT------TEHRCGDGRCIAM 358
Query: 1673 LLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
+CDG DC DE+ C SC + LV + CIP+ +CDG DC D DE +C
Sbjct: 359 EWVCDGDHDCVDKSDEVNC---SCHSQGLVECRNGQCIPSTFQCDGDEDCKDGS-DEENC 414
Query: 1733 S 1733
S
Sbjct: 415 S 415
Score = 74.7 bits (182), Expect = 8e-13
Identities = 50/144 (34%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNME-FPC-STDECI 1670
C F C + QCV S +CDG DC D SDE +C C + + C S +C+
Sbjct: 580 CSPSHFKC-RSGQCVLASRRCDGQADCDDDSDEENCG-------CKERDLWECPSNKQCL 631
Query: 1671 PSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDES 1730
++CDG PDC DE CS C + L CA +++C+ CDG ADC D
Sbjct: 632 KHTVICDGFPDCPDYMDEKNCS--FCQDDELECA-NHACVSRDLWCDGEADCSD------ 682
Query: 1731 SCSDTWTLLGIGL-----AFLMTH 1749
SD W + + + +FLM H
Sbjct: 683 -SSDEWDCVTLSINVNSSSFLMVH 705
Score = 51.2 bits (121), Expect = 9e-06
Identities = 46/150 (30%), Positives = 62/150 (41%), Gaps = 21/150 (14%)
Query: 1598 PECVTGGP-----VPVQPSPCEADQFSCIYTLQCVPLSG----KCDGHEDCIDGSDEMDC 1648
PEC+ G +P + S CEA + C L V S +C + + S+
Sbjct: 197 PECIIDGDDSHGLLPCR-SFCEAAKEGCESVLGMVNYSWPDFLRCSQFRNQTESSNVSRI 255
Query: 1649 PLSPTPP-----LCSNME-FPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALV 1702
SP LC E F C++ CIP L C+G DC DE C +CS
Sbjct: 256 CFSPQQENGKQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHC---NCSENLFH 312
Query: 1703 CASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
C + C+ CDG+ DC D DE +C
Sbjct: 313 C-HTGKCLNYSLVCDGYDDCGDLS-DEQNC 340
Score = 47.0 bits (110), Expect = 2e-04
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 1625 QCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHF 1684
QC+P + +CDG EDC DGSDE +C + T C + C + C+ S C G C
Sbjct: 391 QCIPSTFQCDGDEDCKDGSDEENCSVIQTS--CQEGDQRCLYNPCLDS---CGGSSLCDP 445
Query: 1685 NEDELICS 1692
N CS
Sbjct: 446 NNSLNNCS 453
Score = 45.8 bits (107), Expect = 4e-04
Identities = 17/39 (43%), Positives = 22/39 (56%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSK 112
CS F C SGQC+ CD + DC D+SDE+ C +
Sbjct: 580 CSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKE 618
Score = 45.1 bits (105), Expect = 6e-04
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 65 CGQTQSRKLCSAD---EFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESG 121
CG + C + E C G+CIA E VCD DC D+SDE +C + +G
Sbjct: 331 CGDLSDEQNCDCNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLVECRNG 390
Query: 122 FC 123
C
Sbjct: 391 QC 392
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 1374 PQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYT 1433
P+E + ++ L+ + E P + F CR +C+ + CD + DC D SDE +C
Sbjct: 561 PEENSDNQTCLMPDEYVEECSP--SHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKE 618
Query: 1434 STTGSCNFETSSGNWTTACSLTQDSEDDLD 1463
C T C D D +D
Sbjct: 619 RDLWECPSNKQCLKHTVICDGFPDCPDYMD 648
Score = 42.4 bits (98), Expect = 0.004
Identities = 67/273 (24%), Positives = 100/273 (36%), Gaps = 37/273 (13%)
Query: 477 CIEKLRLCDLVDDCGDRTDEVNCAPEL---------QCNFETGICNWEQDAKDDFDWTRS 527
CI +CD DC D++DEVNC+ QC T C+ ++D KD D
Sbjct: 355 CIAMEWVCDGDHDCVDKSDEVNCSCHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENC 414
Query: 528 QGPTPTLNTGPMK---DNTLGTAKGHYLYIESSEPQAFQDSAALLSPI-LNATDTKGCTF 583
+ G + + L + G L +P ++ + PI L
Sbjct: 415 SVIQTSCQEGDQRCLYNPCLDSCGGSSL----CDPNNSLNNCSQCEPITLELCMNLPYNS 470
Query: 584 RFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQ-------IFGNQGNRWIRKHLNISSR-QP 635
Y + FG R + A W S L Q +F + + +N P
Sbjct: 471 TSYPNYFGHRTQKEASIS--WESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPP 528
Query: 636 FQILVEASVG--DGFTGDIAIDDLSFMDCTLYP-GNLPADLPTPPETSVPVTLPPHNCTD 692
+ L E S + G + + DC+ +P N P+ V P H
Sbjct: 529 CRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSH---- 584
Query: 693 NEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
F CRS G C+ ++CD + DC D SDE +C
Sbjct: 585 --FKCRS-GQCVLASRRCDGQADCDDDSDEENC 614
Score = 42.4 bits (98), Expect = 0.004
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 891 FQDCSPLLSPERK--CTDHEFMCANKHCIAKDKLCDFVNDCADNSDE 935
F DC + + C D E CAN C+++D CD DC+D+SDE
Sbjct: 640 FPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDE 686
Score = 42.0 bits (97), Expect = 0.005
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Query: 1394 CPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACS 1453
C T+ C D +CIA +CD DC D+SDE +C+ ++ C + T C
Sbjct: 342 CNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLVECRNGQCIPS-TFQCD 400
Query: 1454 LTQDSEDDLD 1463
+D +D D
Sbjct: 401 GDEDCKDGSD 410
Score = 39.7 bits (91), Expect = 0.027
Identities = 16/38 (42%), Positives = 21/38 (55%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCS 111
CS + F C +G+C+ VCD DC D SDE C+
Sbjct: 306 CSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCN 343
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 16/86 (18%)
Query: 447 DDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA----PE 502
DD ENC C+ D + C + C++ +CD DC D DE NC+ E
Sbjct: 607 DDSDEENC-------GCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCSFCQDDE 659
Query: 503 LQCNFETGI-----CNWEQDAKDDFD 523
L+C + C+ E D D D
Sbjct: 660 LECANHACVSRDLWCDGEADCSDSSD 685
Score = 39.3 bits (90), Expect = 0.035
Identities = 18/37 (48%), Positives = 20/37 (54%)
Query: 1393 LCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHC 1429
LC +FLC CI L C+ DC D SDEAHC
Sbjct: 268 LCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHC 304
Score = 39.3 bits (90), Expect = 0.035
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 74 CSADEFPCTSGQCIAKESVCDSRQDCSDESDE 105
C DE C + C++++ CD DCSD SDE
Sbjct: 655 CQDDELECANHACVSRDLWCDGEADCSDSSDE 686
Score = 38.9 bits (89), Expect = 0.046
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWV 1181
C CH GKC C+ D+CGD +DE C + T E CG + + +WV
Sbjct: 306 CSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPTTEHR-CG--DGRCIAMEWV 361
Score = 38.9 bits (89), Expect = 0.046
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
Query: 891 FQDCSPLLSPERKCTDH---EFMCANKHCIAKDKLCDFVNDCADNSDETTFICRT 942
+ DC L S E+ C + E C + CIA + +CD +DC D SDE C +
Sbjct: 328 YDDCGDL-SDEQNCDCNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHS 381
Score = 37.7 bits (86), Expect = 0.10
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 73 LCSADE-FPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHL 114
LC E F C SG CI + C+ DC D SDE CS++L
Sbjct: 268 LCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENL 310
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 9/70 (12%)
Query: 463 CEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNC---------APELQCNFETGICN 513
C ++ + HT C+ +CD DDCGD +DE NC + +C +C+
Sbjct: 304 CNCSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPTTEHRCGDGRCIAMEWVCD 363
Query: 514 WEQDAKDDFD 523
+ D D D
Sbjct: 364 GDHDCVDKSD 373
Score = 36.2 bits (82), Expect = 0.30
Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 452 ENCTLPLPAESCEGLD--HFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA--------- 500
+N T +P E E HF CR + C+ R CD DC D +DE NC
Sbjct: 566 DNQTCLMPDEYVEECSPSHFKCRSGQ-CVLASRRCDGQADCDDDSDEENCGCKERDLWEC 624
Query: 501 -PELQCNFETGICNWEQDAKDDFD 523
QC T IC+ D D D
Sbjct: 625 PSNKQCLKHTVICDGFPDCPDYMD 648
Score = 36.2 bits (82), Expect = 0.30
Identities = 15/40 (37%), Positives = 21/40 (52%)
Query: 1402 CRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNF 1441
C + C++ L CD + DCSD SDE C + S +F
Sbjct: 662 CANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSF 701
Score = 35.4 bits (80), Expect = 0.51
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 904 CTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICR-TSSGRC-DFEFDLCSWKQEKD 961
C+++ F C C+ +CD +DC D SDE C T+ RC D W + D
Sbjct: 306 CSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPTTEHRCGDGRCIAMEWVCDGD 365
Query: 962 ED 963
D
Sbjct: 366 HD 367
Score = 35.4 bits (80), Expect = 0.51
Identities = 16/40 (40%), Positives = 20/40 (50%)
Query: 1400 FLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSC 1439
F C KC+ L+CD DC D SDE +C +T C
Sbjct: 311 FHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPTTEHRC 350
Score = 35.4 bits (80), Expect = 0.51
Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 689 NCTDN---EFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
NC N E C DG CI CD +DC DKSDE +C
Sbjct: 339 NCDCNPTTEHRC-GDGRCIAMEWVCDGDHDCVDKSDEVNC 377
Score = 35.4 bits (80), Expect = 0.51
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 1402 CRDKKCIASHLLCDYKPDCSDRSDEAHCA 1430
CR+ +CI S CD DC D SDE +C+
Sbjct: 387 CRNGQCIPSTFQCDGDEDCKDGSDEENCS 415
Score = 35.0 bits (79), Expect = 0.67
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 689 NCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASC 725
NC++N F C + G C+ CD DC D SDE +C
Sbjct: 305 NCSENLFHCHT-GKCLNYSLVCDGYDDCGDLSDEQNC 340
Score = 35.0 bits (79), Expect = 0.67
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 81 CTSGQCIAKESVCDSRQDCSDESDEDPATCSK-HLTCDFESGFCGWEPFL 129
C +GQCI CD +DC D SDE+ CS +C C + P L
Sbjct: 387 CRNGQCIPSTFQCDGDEDCKDGSDEE--NCSVIQTSCQEGDQRCLYNPCL 434
Score = 34.7 bits (78), Expect = 0.87
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 903 KCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICR 941
+C+ F C + C+ + CD DC D+SDE C+
Sbjct: 579 ECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCK 617
Score = 33.5 bits (75), Expect = 1.9
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 690 CTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCV 726
C D+E C + C+ + CD + DC D SDE CV
Sbjct: 655 CQDDELECANHA-CVSRDLWCDGEADCSDSSDEWDCV 690
Score = 33.1 bits (74), Expect = 2.5
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 1404 DKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSC--NFETSSGNWTTACSLTQDSEDD 1461
+K+C+ ++CD PDC D DE +C+ C + S W + DS D+
Sbjct: 627 NKQCLKHTVICDGFPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDE 686
Query: 1462 LD 1463
D
Sbjct: 687 WD 688
Score = 32.7 bits (73), Expect = 3.3
Identities = 11/36 (30%), Positives = 20/36 (55%)
Query: 1123 CPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECG 1158
C + +C +G+C + C+ +C D++DE CG
Sbjct: 580 CSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCG 615
Score = 31.6 bits (70), Expect = 7.4
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 11/71 (15%)
Query: 430 LSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDD 489
++++ V G +D V D++ NC SC CR+ + CI CD +D
Sbjct: 356 IAMEWVCDGDHDCVDKSDEV---NC-------SCHSQGLVECRNGQ-CIPSTFQCDGDED 404
Query: 490 CGDRTDEVNCA 500
C D +DE NC+
Sbjct: 405 CKDGSDEENCS 415
Score = 31.6 bits (70), Expect = 7.4
Identities = 12/32 (37%), Positives = 17/32 (53%)
Query: 1126 GYRECHNGKCYRLEQSCNFVDNCGDNTDENEC 1157
G EC NG+C C+ ++C D +DE C
Sbjct: 383 GLVECRNGQCIPSTFQCDGDEDCKDGSDEENC 414
Score = 31.2 bits (69), Expect = 9.6
Identities = 15/39 (38%), Positives = 19/39 (48%)
Query: 909 FMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRC 947
F+CA+ CI C+ NDC D SDE C + C
Sbjct: 275 FLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHC 313
Score = 31.2 bits (69), Expect = 9.6
Identities = 40/166 (24%), Positives = 60/166 (36%), Gaps = 22/166 (13%)
Query: 65 CGQTQSRKLCSADE---FPCTSG-QCIAKESVCDSRQDCSDESDE--------DPATCSK 112
C + C E + C S QC+ +CD DC D DE D C+
Sbjct: 605 CDDDSDEENCGCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCSFCQDDELECAN 664
Query: 113 HLTCDFESGFCGWEPFLTEDS-HWKLMK-GLNNGEHHFPAADHTANINH---GSFIYLEA 167
H C +C E ++ S W + +N F A +H + + +
Sbjct: 665 H-ACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILS 723
Query: 168 QRSPGVAKLGSPVLTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSL 213
Q + LG P +TKL+ + W L+ HSN T+L
Sbjct: 724 QLACKQMGLGEPSVTKLIQEQE--KEPRW--LTLHSNWESLNGTTL 765
>gi|7706111 8D6 antigen [Homo sapiens]
Length = 282
Score = 79.3 bits (194), Expect = 3e-14
Identities = 46/122 (37%), Positives = 58/122 (47%), Gaps = 10/122 (8%)
Query: 1613 CEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPS 1672
C +F C + CVPL+ +CD DC DGSDE +C + P + C +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEP-----CTQKGQCPPPPGLP- 107
Query: 1673 LLLCDGVPDCHFNEDELI--CSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDES 1730
C GV DC D+ + CS +C G L C S+ CIP RCDG DC D DE
Sbjct: 108 -CPCTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPD-SSDEL 165
Query: 1731 SC 1732
C
Sbjct: 166 GC 167
Score = 45.1 bits (105), Expect = 6e-04
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Query: 670 PADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEV 729
P PT + + P + +C +F CR+ G C+ +CD DC D SDE C +E
Sbjct: 37 PLSTPTSAQAAGPSS---GSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEP 93
Query: 730 CS 731
C+
Sbjct: 94 CT 95
Score = 35.8 bits (81), Expect = 0.39
Identities = 22/80 (27%), Positives = 25/80 (31%), Gaps = 15/80 (18%)
Query: 661 DCTLYPGNLPADLPTPPETSVPVT---------------LPPHNCTDNEFICRSDGHCIE 705
+C + P P PP P T C E C CI
Sbjct: 88 ECRIEPCTQKGQCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIP 147
Query: 706 KMQKCDFKYDCPDKSDEASC 725
+CD DCPD SDE C
Sbjct: 148 LTWRCDGHPDCPDSSDELGC 167
Score = 33.9 bits (76), Expect = 1.5
Identities = 18/37 (48%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 70 SRKLCSADEFPCT-SGQCIAKESVCDSRQDCSDESDE 105
SR C A E CT S CI CD DC D SDE
Sbjct: 128 SRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Score = 33.1 bits (74), Expect = 2.5
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 74 CSADEFPC-TSGQCIAKESVCDSRQDCSDESDED 106
C +F C TSG C+ CD DCSD SDE+
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEE 87
Score = 32.7 bits (73), Expect = 3.3
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 1120 TGFCPLGYRECH-NGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWC 1168
+G CP +C +G C L C+ +C D +DE EC +KG C
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPCTQKGQC 100
Score = 32.3 bits (72), Expect = 4.3
Identities = 19/45 (42%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 1386 SVGEISELCPEITDFLCRDKK-CIASHLLCDYKPDCSDRSDEAHC 1429
+ G S CP T F CR C+ CD DCSD SDE C
Sbjct: 46 AAGPSSGSCPP-TKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC 89
Score = 32.3 bits (72), Expect = 4.3
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 1692 SNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSC 1732
S+ SC C +S C+P RCD DC D DE C
Sbjct: 50 SSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGS-DEEEC 89
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 75.1 bits (183), Expect = 6e-13
Identities = 48/160 (30%), Positives = 81/160 (50%), Gaps = 16/160 (10%)
Query: 505 CNFETG----ICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQ 560
C F G C+WE D W+ T TGP++D+T G+++Y ++ E Q
Sbjct: 650 CEFGWGSHKTFCHWEHDNHVQLKWS-----VLTSKTGPIQDHT---GDGNFIYSQADENQ 701
Query: 561 AFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWS-DSRGQLLWQIFGNQ 619
+ A L+SP++ + ++ C F+YHM G + L + R + QL+W G+Q
Sbjct: 702 KGK-VARLVSPVVYSQNSAHC-MTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQ 759
Query: 620 GNRWIRKHLNI-SSRQPFQILVEASVGDGFTGDIAIDDLS 658
G+ W + + S + +Q++ E +G G G IA+DD+S
Sbjct: 760 GDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDIS 799
Score = 68.6 bits (166), Expect = 5e-11
Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 15/141 (10%)
Query: 774 PSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQV 833
P DHT DG ++Y+ + + G A +++P++ + FW HM+G+ VG+L+V
Sbjct: 682 PIQDHTG---DGNFIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRV 738
Query: 834 LI---KKDNVTSKLWAQTGQQGAQWKRAEVFL--GIRSHTQIVFRAKRGISYIGDVAVDD 888
+ K + +W G QG WK V L ++ + Q++F + G +G +AVDD
Sbjct: 739 KLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLY-QVIFEGEIGKGNLGGIAVDD 797
Query: 889 ISF------QDCSPLLSPERK 903
IS +DC+ ++K
Sbjct: 798 ISINNHISQEDCAKPADLDKK 818
Score = 63.2 bits (152), Expect = 2e-09
Identities = 45/153 (29%), Positives = 79/153 (51%), Gaps = 14/153 (9%)
Query: 954 CSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSP 1013
C W+ + W++ S T P DHT G++I+ ++ Q + AR+ SP
Sbjct: 661 CHWEHDNHVQLKWSVLTSK-----TGPIQDHT---GDGNFIYSQA-DENQKGKVARLVSP 711
Query: 1014 VI-SKRSKNCKIIFHYHMYGNGIGALTL-MQVSVTNQTKVLLNLTV-EQGNFWRREELSL 1070
V+ S+ S +C + F YHM G+ +G L + ++ + L+ + + QG+ W+ + L
Sbjct: 712 VVYSQNSAHC-MTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLL 770
Query: 1071 FGD-EDFQLKFEGRVGKGQRGDIALDDIVLTEN 1102
+ +Q+ FEG +GKG G IA+DDI + +
Sbjct: 771 HKSLKLYQVIFEGEIGKGNLGGIAVDDISINNH 803
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 1440 NFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKE 1499
N E G+ T C D+ L W++ + P DHT G G +F+Y + +++
Sbjct: 649 NCEFGWGSHKTFCHWEHDNHVQLKWSVLTSKTG----PIQDHT-GDG-NFIYSQADENQK 702
Query: 1500 GSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKV---YTIEESGLNILVWSVIGNK 1556
G VAR+ + + + C + FW++M +G L+V Y E + LVW IG++
Sbjct: 703 GKVARLVSPVVYSQNSAHC-MTFWYHMSGSH-VGTLRVKLRYQKPEE-YDQLVWMAIGHQ 759
Query: 1557 RTGWTYGSVPL-SSNSPFKVAFEADLDGNEDIFIALDDIS 1595
W G V L S ++V FE ++ IA+DDIS
Sbjct: 760 GDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDIS 799
Score = 50.4 bits (119), Expect = 2e-05
Identities = 47/208 (22%), Positives = 88/208 (42%), Gaps = 26/208 (12%)
Query: 249 FQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEAIS 308
FQL TVL++ +D ++ QS+F F W +
Sbjct: 618 FQLTGGTTVLATEKPTVID-----------------STIQSEFPTYGFNCEF-GWGSHKT 659
Query: 309 GDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKLQSPT-FSQ 367
H++ Q + S P +DH+ G+F++ + +VA+L SP +SQ
Sbjct: 660 FCHWEHDNHVQLKWSVLTSKTGPIQDHT---GDGNFIYSQADENQKGKVARLVSPVVYSQ 716
Query: 368 TGPGCILSFWFYNYGLSVGAAELQLHMENSHD-STVIWRVLYNQGKQWLEATIQLGRLSQ 426
C ++FW++ G VG ++L + + ++W + +QG W E + L + +
Sbjct: 717 NSAHC-MTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLK 775
Query: 427 PFHLSLD-KVSLGIYDGVSAIDDIRFEN 453
+ + + ++ G G+ A+DDI N
Sbjct: 776 LYQVIFEGEIGKGNLGGI-AVDDISINN 802
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,035,623
Number of Sequences: 37866
Number of extensions: 3886053
Number of successful extensions: 12288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 8936
Number of HSP's gapped (non-prelim): 2253
length of query: 1817
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1700
effective length of database: 13,817,196
effective search space: 23489233200
effective search space used: 23489233200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.