Search of human proteins with 239742514

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239742514 PREDICTED: similar to Putative POM121-like protein
1-like [Homo sapiens]
         (896 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239742514 PREDICTED: similar to Putative POM121-like protein ...  1775   0.0  
gi|239742580 PREDICTED: similar to Putative POM121-like protein ...  1659   0.0  
gi|239757688 PREDICTED: similar to POM121-like 1, partial [Homo ...   510   e-144
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]   161   2e-39
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]          161   3e-39
gi|239754624 PREDICTED: similar to hCG1998564 [Homo sapiens]          138   3e-32
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...   112   2e-24
gi|253683544 POM121 membrane glycoprotein-like 2 [Homo sapiens]       107   4e-23
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    77   5e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        77   9e-14
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        75   3e-13
gi|112421134 hypothetical protein LOC23742 [Homo sapiens]              72   2e-12
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        69   1e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    69   1e-11
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    62   2e-09
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    62   2e-09
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    62   2e-09
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    62   3e-09
gi|167736355 mucin 4 isoform a [Homo sapiens]                          61   4e-09
gi|91982772 mucin 17 [Homo sapiens]                                    61   4e-09
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    60   9e-09
gi|151301154 mucin 6, gastric [Homo sapiens]                           59   2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    58   4e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   1e-07
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         56   1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   5e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         52   2e-06
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  52   2e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     52   2e-06
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]               51   5e-06

>gi|239742514 PREDICTED: similar to Putative POM121-like protein
           1-like [Homo sapiens]
          Length = 896

 Score = 1775 bits (4597), Expect = 0.0
 Identities = 896/896 (100%), Positives = 896/896 (100%)

Query: 1   MPEQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSE 60
           MPEQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSE
Sbjct: 1   MPEQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSE 60

Query: 61  IRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP 120
           IRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP
Sbjct: 61  IRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP 120

Query: 121 QAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLEL 180
           QAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLEL
Sbjct: 121 QAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLEL 180

Query: 181 GYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP 240
           GYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP
Sbjct: 181 GYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP 240

Query: 241 TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRD 300
           TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRD
Sbjct: 241 TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRD 300

Query: 301 SAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLA 360
           SAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLA
Sbjct: 301 SAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLA 360

Query: 361 SATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLA 420
           SATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLA
Sbjct: 361 SATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLA 420

Query: 421 HSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKA 480
           HSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKA
Sbjct: 421 HSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKA 480

Query: 481 ISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPST 540
           ISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPST
Sbjct: 481 ISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPST 540

Query: 541 APVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSA 600
           APVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSA
Sbjct: 541 APVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSA 600

Query: 601 PAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSC 660
           PAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSC
Sbjct: 601 PAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSC 660

Query: 661 LKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADT 720
           LKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADT
Sbjct: 661 LKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADT 720

Query: 721 APGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSK 780
           APGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSK
Sbjct: 721 APGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSK 780

Query: 781 APTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHS 840
           APTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHS
Sbjct: 781 APTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHS 840

Query: 841 GDSAQDTSLIPAPFTPASRDAGVRRMFCVRNCLRGLGLFLLVFSLFFLLTWASFSF 896
           GDSAQDTSLIPAPFTPASRDAGVRRMFCVRNCLRGLGLFLLVFSLFFLLTWASFSF
Sbjct: 841 GDSAQDTSLIPAPFTPASRDAGVRRMFCVRNCLRGLGLFLLVFSLFFLLTWASFSF 896


>gi|239742580 PREDICTED: similar to Putative POM121-like protein
           1-like [Homo sapiens]
          Length = 897

 Score = 1659 bits (4296), Expect = 0.0
 Identities = 849/899 (94%), Positives = 863/899 (95%), Gaps = 5/899 (0%)

Query: 1   MPEQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSE 60
           MPEQDKDPRVQENPDD RTVPEVTGDARSAFWPLRDNGG SPFVPRPGPLQTDLHAQSSE
Sbjct: 1   MPEQDKDPRVQENPDDQRTVPEVTGDARSAFWPLRDNGGPSPFVPRPGPLQTDLHAQSSE 60

Query: 61  IRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP 120
           IRYN TSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP
Sbjct: 61  IRYNHTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP 120

Query: 121 QAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLEL 180
           QAVSSGHTRCEK ADTAPGQT+AP GGSPRSQ SRPRRRKIPLLP RRGEPLM+PPPLEL
Sbjct: 121 QAVSSGHTRCEKGADTAPGQTIAPTGGSPRSQDSRPRRRKIPLLPRRRGEPLMLPPPLEL 180

Query: 181 GYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP 240
           GYRVTAEDLHLEK+ AFQRINSALHVEDKAI DCRPSRPSHTLSSLATGASGGPPVSKAP
Sbjct: 181 GYRVTAEDLHLEKETAFQRINSALHVEDKAIPDCRPSRPSHTLSSLATGASGGPPVSKAP 240

Query: 241 TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRD 300
           TMDAQQDRPKSQDCLGLVAPLASAAEV STAPVSGKK RPPGPLFSSSDPLPATS HSRD
Sbjct: 241 TMDAQQDRPKSQDCLGLVAPLASAAEVPSTAPVSGKKHRPPGPLFSSSDPLPATSYHSRD 300

Query: 301 SAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLA 360
           +AQVTS+IPA FTAASRDAGMRRTRSAPAAA AAPPPSTLN TSGSLLNAVDGGPSHFLA
Sbjct: 301 TAQVTSLIPATFTAASRDAGMRRTRSAPAAATAAPPPSTLNNTSGSLLNAVDGGPSHFLA 360

Query: 361 SATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSS--HSSTEGLPELKRRRGPASSHCQ 418
           SATAAARAQRSEVRYNQRSQ SRTRSCLKRNASSSS  HSSTEGL ELKRRRGPASSHCQ
Sbjct: 361 SATAAARAQRSEVRYNQRSQTSRTRSCLKRNASSSSSSHSSTEGLQELKRRRGPASSHCQ 420

Query: 419 LAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVED 478
           LAHSSS TVSEDGPQAVSSGH RCE +A TAPGQTLAPRGGSPRSQASRPHINSAL+VED
Sbjct: 421 LAHSSSNTVSEDGPQAVSSGH-RCENKAGTAPGQTLAPRGGSPRSQASRPHINSALYVED 479

Query: 479 KAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELP 538
           KAISDCRPSRPSHTLSSLATGAS GPPVSKAPTMDAQQDRPKSQDCLGL+APLASAAE+P
Sbjct: 480 KAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVP 539

Query: 539 STAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGT 598
           STAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTS+IPA FTAASRDAGMRRTRPGT
Sbjct: 540 STAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSLIPATFTAASRDAGMRRTRPGT 599

Query: 599 SAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTR 658
           SAPAAAAAA PPSTLNPTSGSLLNAVD GPSHFLASATAAARA+RS+VRYNQRSQTSRTR
Sbjct: 600 SAPAAAAAALPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQTSRTR 659

Query: 659 SCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCE-K 717
           SCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLA SSSNTVSEDGPQAVSS   RCE K
Sbjct: 660 SCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLAHSSSNTVSEDGPQAVSS-GHRCENK 718

Query: 718 ADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP 777
           A TAPGQTLAPRGG PRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP
Sbjct: 719 AGTAPGQTLAPRGGYPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP 778

Query: 778 VSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATS 837
           VSKAPTMDAQQDRPKSQDCLGL+APLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATS
Sbjct: 779 VSKAPTMDAQQDRPKSQDCLGLLAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATS 838

Query: 838 SHSGDSAQDTSLIPAPFTPASRDAGVRRMFCVRNCLRGLGLFLLVFSLFFLLTWASFSF 896
           SHSGDSAQDTSLIPAPFTPASRDAG+RRMF VRNCLRGLGLFLLVFS FFLLTWASFSF
Sbjct: 839 SHSGDSAQDTSLIPAPFTPASRDAGIRRMFRVRNCLRGLGLFLLVFSFFFLLTWASFSF 897


>gi|239757688 PREDICTED: similar to POM121-like 1, partial [Homo
           sapiens]
          Length = 346

 Score =  510 bits (1313), Expect = e-144
 Identities = 261/305 (85%), Positives = 270/305 (88%)

Query: 1   MPEQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSE 60
           MPEQDKDPRVQENP D R VPEVTGDA SAF PLRDNGGLSPFVPRPGPLQTDLHAQ SE
Sbjct: 42  MPEQDKDPRVQENPGDQRRVPEVTGDAPSAFRPLRDNGGLSPFVPRPGPLQTDLHAQRSE 101

Query: 61  IRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRP 120
           IRYNQTSQTSWTSS T RNAISSSYSSTGGLPGLK+RRGPASS CQLTLS SKTVSEDRP
Sbjct: 102 IRYNQTSQTSWTSSCTNRNAISSSYSSTGGLPGLKRRRGPASSHCQLTLSSSKTVSEDRP 161

Query: 121 QAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLEL 180
           QAVSSGHT+CEKAAD APGQTL  R  S  S+ASRP   K PLLP RRGEPLM+PPPLEL
Sbjct: 162 QAVSSGHTQCEKAADIAPGQTLTLRNDSSTSEASRPSTHKFPLLPRRRGEPLMLPPPLEL 221

Query: 181 GYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP 240
           GYRVT EDL  EK+AAFQRINSAL VEDKAISDCRPS PSHTLSSLATGASG P VSKA 
Sbjct: 222 GYRVTVEDLDREKEAAFQRINSALQVEDKAISDCRPSWPSHTLSSLATGASGLPAVSKAS 281

Query: 241 TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRD 300
           +MDAQQ+  KSQDCLGL+APLASAAEV STAPVSGKK RPPGPLFSSSDPLPATSS S+D
Sbjct: 282 SMDAQQETHKSQDCLGLLAPLASAAEVPSTAPVSGKKHRPPGPLFSSSDPLPATSSDSQD 341

Query: 301 SAQVT 305
           SAQVT
Sbjct: 342 SAQVT 346



 Score =  303 bits (775), Expect = 6e-82
 Identities = 170/250 (68%), Positives = 178/250 (71%), Gaps = 42/250 (16%)

Query: 368 AQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTV 427
           AQRSE+RYNQ SQ S T SC  RNA SSS+SST GLP LKRRRGPASSHCQL  SSSKTV
Sbjct: 97  AQRSEIRYNQTSQTSWTSSCTNRNAISSSYSSTGGLPGLKRRRGPASSHCQLTLSSSKTV 156

Query: 428 SEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRP------------------- 468
           SED PQAVSSGHT+CEK AD APGQTL  R  S  S+ASRP                   
Sbjct: 157 SEDRPQAVSSGHTQCEKAADIAPGQTLTLRNDSSTSEASRPSTHKFPLLPRRRGEPLMLP 216

Query: 469 -----------------------HINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPP 505
                                   INSAL VEDKAISDCRPS PSHTLSSLATGAS  P 
Sbjct: 217 PPLELGYRVTVEDLDREKEAAFQRINSALQVEDKAISDCRPSWPSHTLSSLATGASGLPA 276

Query: 506 VSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATS 565
           VSKA +MDAQQ+  KSQDCLGLLAPLASAAE+PSTAPVSGKKHRPPGPLFSSSDPLPATS
Sbjct: 277 VSKASSMDAQQETHKSQDCLGLLAPLASAAEVPSTAPVSGKKHRPPGPLFSSSDPLPATS 336

Query: 566 SHSRDSAQVT 575
           S S+DSAQVT
Sbjct: 337 SDSQDSAQVT 346



 Score =  287 bits (735), Expect = 3e-77
 Identities = 166/250 (66%), Positives = 175/250 (70%), Gaps = 43/250 (17%)

Query: 641 ARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTV 700
           A+RS++RYNQ SQTS T SC  RNA SSS+SST GL  LKRRRGPASSHCQL LSSS TV
Sbjct: 97  AQRSEIRYNQTSQTSWTSSCTNRNAISSSYSSTGGLPGLKRRRGPASSHCQLTLSSSKTV 156

Query: 701 SEDGPQAVSSRDTRCEKA-DTAPGQTLAPRGGSPRSQASRP------------------- 740
           SED PQAVSS  T+CEKA D APGQTL  R  S  S+ASRP                   
Sbjct: 157 SEDRPQAVSSGHTQCEKAADIAPGQTLTLRNDSSTSEASRPSTHKFPLLPRRRGEPLMLP 216

Query: 741 -----------------------RINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP 777
                                  RINSAL VEDKAISDCRPS PSHTLSSLATGASG P 
Sbjct: 217 PPLELGYRVTVEDLDREKEAAFQRINSALQVEDKAISDCRPSWPSHTLSSLATGASGLPA 276

Query: 778 VSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATS 837
           VSKA +MDAQQ+  KSQDCLGL+APLASAAEV STAPVSGKKHRPPGPLFSSSDPLPATS
Sbjct: 277 VSKASSMDAQQETHKSQDCLGLLAPLASAAEVPSTAPVSGKKHRPPGPLFSSSDPLPATS 336

Query: 838 SHSGDSAQDT 847
           S S DSAQ T
Sbjct: 337 SDSQDSAQVT 346


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score =  161 bits (408), Expect = 2e-39
 Identities = 194/669 (28%), Positives = 275/669 (41%), Gaps = 93/669 (13%)

Query: 4   QDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIRY 63
           +++D    +  ++ R   + +G   SAF PL  +G  + FVP+PG L+  L++QSS+   
Sbjct: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120

Query: 64  NQTSQTSWTSS----------STKRNAISSSYSSTGGLPGLKQRRGP--------ASSRC 105
           N+ S++S  SS          S+ RNAI+SSYSST G+  L +R GP        ASSR 
Sbjct: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180

Query: 106 QLTLSYSKTVSEDRPQAVSSGHT--------RCEKAADTAPGQTLAPRGGSPRSQASRPR 157
           Q     +K + E+     SS  T        + EKAADT P +       S    + + R
Sbjct: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQ-R 239

Query: 158 RRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPS 217
           +RK+ LLPSRRGE L +PPP +LGY +TAEDL LEK+A+ Q  N AL  +  A S+    
Sbjct: 240 KRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTE 299

Query: 218 RPSHTLSS----LATGASGGPPVS-KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAP 272
            P  T  S    L   A+  PP S  AP+ +   +  K       + P   +A  ++T  
Sbjct: 300 TPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEA 359

Query: 273 VSGKKQ---RPPGPLFSSSDP--LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSA 327
           +S  K     PP  L  S  P  LP+ S  S+    +  +IPAP    + D     T  A
Sbjct: 360 LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQA 419

Query: 328 PAA----AAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEV-----RYNQR 378
             A    A +AP P+   P    L    +  PS   A A ++A      +     +  + 
Sbjct: 420 ETATKPQATSAPSPA---PKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKE 476

Query: 379 SQISRTRSCLKRNASSSSHSSTEGL------PELKRRRGPASSHCQLAHSSSKTVSEDGP 432
                  S      SSSS  +T         P       PAS           T     P
Sbjct: 477 GPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAP 536

Query: 433 QAVSSGHT-RCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSH 491
              +   T      +  AP  + +P   S    A    INS   V   ++S         
Sbjct: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINS---VSSSSVS--------- 584

Query: 492 TLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPP 551
           T +S AT AS+ P +  AP   A    P     +G +        LP+T  V+       
Sbjct: 585 TTTSTATAASQ-PFLFGAPQASAASFTP----AMGSIFQFGKPPALPTTTTVT------- 632

Query: 552 GPLFSSSDPL---PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAP------A 602
              FS S P     ATSS + D +   S +     A S    +  T   TS P       
Sbjct: 633 --TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTL--TFSNTSTPTFNIPFG 688

Query: 603 AAAAAPPPS 611
           ++A +P PS
Sbjct: 689 SSAKSPLPS 697



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 96/403 (23%), Positives = 142/403 (35%), Gaps = 114/403 (28%)

Query: 353 GGPSHFLASATAAAR---AQRSEVRYNQRSQISRTRSCL----------KRNASSSSHSS 399
           G P+ F+    +  R   +Q S+   N+RS+ S   S             RNA +SS+SS
Sbjct: 95  GVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSS 154

Query: 400 TEGLPELKRRRGP--------ASSHCQLAHSSSKTVSEDGPQAVSSGHT--------RCE 443
           T G+ +L +R GP        ASS  Q     +K + E+     SS  T        + E
Sbjct: 155 TRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGE 214

Query: 444 KRADTAPG---------------------QTLAPRGGSPRSQASRPHINSALHVED---- 478
           K ADT P                      Q L  R G   +    P +  ++  ED    
Sbjct: 215 KAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLE 274

Query: 479 --------------------KAISDCRPS-RPSHTLSSLATGASRGPPVSK-APTMDAQQ 516
                                ++++  P+ +PS T + L   A+  PP S  AP+ +   
Sbjct: 275 KKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFT-LPAAATASPPTSLLAPSTNPLL 333

Query: 517 DRPKSQDCLGLLAPLASAAELPSTAPVSGKKHR---PPGPLFSSSDP--LPATSSHSRDS 571
           +  K       L P   +A   +T  +S  K     PP  L  S  P  LP+ S  S+  
Sbjct: 334 ESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPP 393

Query: 572 AQVTSMIPAPFTAASRDA------------------------------GMRRTRPGTSAP 601
             +  +IPAP    + D                               G + T P  S+P
Sbjct: 394 TTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP--SSP 451

Query: 602 AAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRS 644
           AA AA+       P   +   +  EGP+    S TA A +  S
Sbjct: 452 AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSS 494



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 78/326 (23%), Positives = 122/326 (37%), Gaps = 75/326 (23%)

Query: 597 GTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSR 656
           G SA     A+  P++  P  GSL   ++   S    +     R+R S +     + TS 
Sbjct: 84  GHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNK----RSRSSSMSSLTGAYTSG 139

Query: 657 TRSCLKRNASSSSHSSTEGLQELKRRRGPASSH------------------------CQL 692
             S   RNA +SS+SST G+ +L +R GP+SS                         C  
Sbjct: 140 IPSS-SRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHH 198

Query: 693 ALSSSNTVSEDGPQAVSSRDTRCEK-----ADTAPG---------QTLAPRGGSPRSQAS 738
           + SS+   ++   Q   + DT   K     + + PG         Q L  R G   +   
Sbjct: 199 SSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPP 258

Query: 739 RPRINSALHVED------------------------KAISDCRP-SRPSHTLSSLATGAS 773
            P++  ++  ED                         ++++  P ++PS T  +L   A+
Sbjct: 259 PPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF-TLPAAAT 317

Query: 774 GGPPVS-KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKH---RPPGPLFSS 829
             PP S  AP+ +   +  K       + P   +A  ++T  +S  K     PP  L  S
Sbjct: 318 ASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQS 377

Query: 830 SDP--LPATSSHSGDSAQDTSLIPAP 853
             P  LP+ S  S        LIPAP
Sbjct: 378 GPPGLLPSPSFDSKPPTTLLGLIPAP 403


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score =  161 bits (407), Expect = 3e-39
 Identities = 185/662 (27%), Positives = 277/662 (41%), Gaps = 81/662 (12%)

Query: 4   QDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIRY 63
           +++D    +  ++ R   + +G   SAF PL  NG  + FVP+PG L+  L++QSS+   
Sbjct: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHL 120

Query: 64  NQTSQTSWTSS----------STKRNAISSSYSSTGGLPGLKQRRGP--------ASSRC 105
           N+ S++S  SS          S+ RNAI+SSYSST G+  L +R GP        ASSR 
Sbjct: 121 NKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180

Query: 106 QLTLSYSKTVSEDRPQAVSSGHT--------RCEKAADTAPGQTLAPRGGSPRSQASRPR 157
           Q     +K + E+     SS  T        + EKAADT P +       S    + + R
Sbjct: 181 QTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQNSNSQSTPGSSGQ-R 239

Query: 158 RRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPS 217
           +RK+ LLPSRRGE L +PPP +LGY +TAEDL LEK+A+ Q  N AL  +  A S+    
Sbjct: 240 KRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTE 299

Query: 218 RPSHTLSS----LATGASGGPPVS-KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAP 272
            P  T  S    L   A   PP S  AP+ +   +  K       + P   +A  ++T  
Sbjct: 300 TPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEA 359

Query: 273 VSGKKQ---RPPGPLFSSSDP--LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSA 327
           +S  K     PP  L  S  P  LP+ S  S+    +  +IPAP    + D     T  A
Sbjct: 360 LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQA 419

Query: 328 PAA----AAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISR 383
             A    A +AP P+   P    L    +  PS   A A ++A      + +    +  +
Sbjct: 420 ETATKPQATSAPSPA---PKQSFLFGTQNTSPSSPAAPAASSAPPMFKPI-FTAPPKSEK 475

Query: 384 TRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQA---VSSGHT 440
                   + +++  S+  LP       P         +     S  GP A   + +   
Sbjct: 476 EGPTPPGPSVTATAPSSSSLPTTTSTTAP---------TFQPVFSSMGPPASVPLPAPFF 526

Query: 441 RCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGA 500
           +      TAP  T     G   + ++   I SA    D A      S+P+      +  +
Sbjct: 527 KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSA------SKPAFGFGINSVSS 580

Query: 501 SRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDP 560
           S     +   T  +Q             AP ASAA   S  P  G   +     F     
Sbjct: 581 SSVSTTTSTATAASQP--------FLFGAPQASAA---SFTPAMGSIFQ-----FGKPPA 624

Query: 561 LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSL 620
           LP T++ +  S  + + +P   ++++ D     +   TSAP  A ++ P  T + TS   
Sbjct: 625 LPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAP--ATSSQPTLTFSNTSTPT 682

Query: 621 LN 622
            N
Sbjct: 683 FN 684



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 97/404 (24%), Positives = 143/404 (35%), Gaps = 114/404 (28%)

Query: 352 DGGPSHFLASATAAAR---AQRSEVRYNQRSQISRTRSCL----------KRNASSSSHS 398
           +G P+ F+    +  R   +Q S+   N+RS+ S   S             RNA +SS+S
Sbjct: 94  NGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYS 153

Query: 399 STEGLPELKRRRGP--------ASSHCQLAHSSSKTVSEDGPQAVSSGHT--------RC 442
           ST G+ +L +R GP        ASS  Q     +K + E+     SS  T        + 
Sbjct: 154 STRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQG 213

Query: 443 EKRADTAPG---------------------QTLAPRGGSPRSQASRPHINSALHVED--- 478
           EK ADT P                      Q L  R G   +    P +  ++  ED   
Sbjct: 214 EKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDL 273

Query: 479 ---------------------KAISDCRP-SRPSHTLSSLATGASRGPPVSK-APTMDAQ 515
                                 ++++  P ++PS T + L   A   PP S  AP+ +  
Sbjct: 274 EKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFT-LPAAAPASPPTSLLAPSTNPL 332

Query: 516 QDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHR---PPGPLFSSSDP--LPATSSHSRD 570
            +  K       L P   +A   +T  +S  K     PP  L  S  P  LP+ S  S+ 
Sbjct: 333 LESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKP 392

Query: 571 SAQVTSMIPAPFTAASRDA------------------------------GMRRTRPGTSA 600
              +  +IPAP    + D                               G + T P  S+
Sbjct: 393 PTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP--SS 450

Query: 601 PAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRS 644
           PAA AA+  P    P   +   +  EGP+    S TA A +  S
Sbjct: 451 PAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSS 494



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 73/308 (23%), Positives = 113/308 (36%), Gaps = 83/308 (26%)

Query: 628 PSHFLASATAAARARRSQV---RYNQRSQTSRTRSCL----------KRNASSSSHSSTE 674
           P+ F+    +  R   SQ      N+RS++S   S             RNA +SS+SST 
Sbjct: 97  PASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTR 156

Query: 675 GLQELKRRRGPASSHCQLALSSSNTVSEDGPQAV----------------SSRDTRCEK- 717
           G+ +L +R GP+SS      SS +   E   + +                + R+++ EK 
Sbjct: 157 GISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQGEKA 216

Query: 718 ADTAPG---------------------QTLAPRGGSPRSQASRPRINSALHVED------ 750
           ADT P                      Q L  R G   +    P++  ++  ED      
Sbjct: 217 ADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKK 276

Query: 751 ------------------KAISDCRP-SRPSHTLSSLATGASGGPPVS-KAPTMDAQQDR 790
                              ++++  P ++PS T  +L   A   PP S  AP+ +   + 
Sbjct: 277 ASLQWFNQALEDKSDAASNSVTETPPITQPSFTF-TLPAAAPASPPTSLLAPSTNPLLES 335

Query: 791 PKSQDCLGLVAPLASAAEVSSTAPVSGKKH---RPPGPLFSSSDP--LPATSSHSGDSAQ 845
            K       + P   +A  ++T  +S  K     PP  L  S  P  LP+ S  S     
Sbjct: 336 LKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT 395

Query: 846 DTSLIPAP 853
              LIPAP
Sbjct: 396 LLGLIPAP 403


>gi|239754624 PREDICTED: similar to hCG1998564 [Homo sapiens]
          Length = 526

 Score =  138 bits (347), Expect = 3e-32
 Identities = 108/313 (34%), Positives = 150/313 (47%), Gaps = 34/313 (10%)

Query: 4   QDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIRY 63
           +++D    +  ++ R   + +G   SAF PL  NG  + FVP+PG L+  L++QSS+   
Sbjct: 189 EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHL 248

Query: 64  NQTSQTSWTSS----------STKRNAISSSYSSTGGLPGLKQRRGP--------ASSRC 105
           N+ S++S  SS          S+ RNAI+SSYSST G+  L +R GP        ASSR 
Sbjct: 249 NKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 308

Query: 106 QLTLSYSKTVSEDRPQAVSSGHT--------RCEKAADTAPGQTLAPRGGSPRSQASRPR 157
           Q     +K + E+     SS  T        + EKAADT P +       S    + + R
Sbjct: 309 QTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQNSNSQSTPGSSGQ-R 367

Query: 158 RRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPS 217
           +RK+ LLPSRRGE L +PPP +LGY +TAEDL LEK+A+ Q  N AL  +  A S+    
Sbjct: 368 KRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTE 427

Query: 218 RPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK 277
            P  T  S         P S   ++ A    P       L+  L       S  P  G+ 
Sbjct: 428 TPPITQPSFTFTLPAAAPASPPTSLLAPSTNP-------LLESLKKMQTPPSLPPCPGEL 480

Query: 278 QRPPGPLFSSSDP 290
           +   G    SS P
Sbjct: 481 EWGRGSSLLSSIP 493



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 39/128 (30%), Positives = 56/128 (43%), Gaps = 29/128 (22%)

Query: 352 DGGPSHFLASATAAAR---AQRSEVRYNQRSQISRTRSCL----------KRNASSSSHS 398
           +G P+ F+    +  R   +Q S+   N+RS+ S   S             RNA +SS+S
Sbjct: 222 NGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYS 281

Query: 399 STEGLPELKRRRG--------PASSHCQLAHSSSKTVSEDGPQAVSSGHT--------RC 442
           ST G+ +L +R G        PASS  Q     +K + E+     SS  T        + 
Sbjct: 282 STRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQG 341

Query: 443 EKRADTAP 450
           EK ADT P
Sbjct: 342 EKAADTTP 349



 Score = 37.4 bits (85), Expect = 0.063
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 13/108 (12%)

Query: 628 PSHFLASATAAARARRSQV---RYNQRSQTSRTRSCL----------KRNASSSSHSSTE 674
           P+ F+    +  R   SQ      N+RS++S   S             RNA +SS+SST 
Sbjct: 225 PASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTR 284

Query: 675 GLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAP 722
           G+ +L +R GP+SS      SS +   E   + +   +     + + P
Sbjct: 285 GISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTP 332


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score =  112 bits (279), Expect = 2e-24
 Identities = 154/576 (26%), Positives = 224/576 (38%), Gaps = 74/576 (12%)

Query: 72  TSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHT--- 128
           TS   KRN  SSS  S+           PASSR Q     +K + E+     SS  T   
Sbjct: 7   TSELWKRNGPSSSPFSS-----------PASSRSQTPERPAKKIREEEMCHHSSSSTPLA 55

Query: 129 -----RCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYR 183
                + EKAADT P +       S    + + R+RK+ LLPSRRGE L +PPP +LGY 
Sbjct: 56  ADKESQGEKAADTTPRKKQNSNSQSTPGSSGQ-RKRKVQLLPSRRGEQLTLPPPPQLGYS 114

Query: 184 VTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSS----LATGASGGPPVS-K 238
           +TAEDL LEK+A+ Q  N AL  +  A S+     P  T  S    L   A   PP S  
Sbjct: 115 ITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLL 174

Query: 239 APTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQ---RPPGPLFSSSDP--LPA 293
           AP+ +   +  K       + P   +A  ++T  +S  K     PP  L  S  P  LP+
Sbjct: 175 APSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPS 234

Query: 294 TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAA----AAAAPPPSTLNPTSGSLLN 349
            S  S     +  +IPAP    + D     T  A       A +AP P+   P    L  
Sbjct: 235 PSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPA---PKQSFLFG 291

Query: 350 AVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRR 409
             +  PS   A A ++A      + +    +  +        + S++  S+  LP     
Sbjct: 292 TQNTSPSSPAAPAASSASPMFKPI-FTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTST 350

Query: 410 RGPASSHCQLAHSSSKTVSEDGPQA---VSSGHTRCEKRADTAPGQTLAPRGGSPRSQAS 466
             P         +     S  GP A   + +   +      TAP  T     G   + ++
Sbjct: 351 TAP---------TFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSA 401

Query: 467 RPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLG 526
              I SA    D A      S+P+      +  +S     +   T  +Q           
Sbjct: 402 VAPITSASPSTDSA------SKPAFGFGINSVSSSSVSTTTSTATAASQP--------FL 447

Query: 527 LLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAAS 586
             AP ASAA   S  P  G   +     F     LP T++ +  S  + + +P   ++++
Sbjct: 448 FGAPQASAA---SFTPAMGSIFQ-----FGKPPALPTTTTVTTFSQSLPTAVPTATSSSA 499

Query: 587 RDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLN 622
            D     +   TSAP  A ++ P  T + TS    N
Sbjct: 500 ADFSGFGSTLATSAP--ATSSQPTLTFSNTSTPTFN 533


>gi|253683544 POM121 membrane glycoprotein-like 2 [Homo sapiens]
          Length = 1035

 Score =  107 bits (268), Expect = 4e-23
 Identities = 181/704 (25%), Positives = 262/704 (37%), Gaps = 118/704 (16%)

Query: 6   KDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSE----I 61
           ++P   E+ D  R  PE      SAF PL  NG L+ FVPRPGPL+  LH+  S+     
Sbjct: 174 EEPLFPESLDSKRRSPETRP---SAFKPLMKNGTLTSFVPRPGPLKRSLHSWGSDHSLTK 230

Query: 62  RYNQTSQTSWTS------SSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTV 115
           R N +S +S  S       S+KRNAI SSYSS        +R  P             +V
Sbjct: 231 RPNCSSMSSLASIYRGGTLSSKRNAIGSSYSSCRNFSDPWKRSVP-------------SV 277

Query: 116 SEDRPQAVSSGHTRCEKAADTAP-GQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMM 174
           S + P+        C + +   P        GG   S++S  + +KIP LPS     +  
Sbjct: 278 SFETPEWPIKKEKSCHRPSSPVPLVSDFESLGG---SESSGQQNQKIPQLPSSPENLVSE 334

Query: 175 PPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGP 234
            PP +LGY V+ E+L L K+A  Q  N+A     +  +D  P        SL+       
Sbjct: 335 IPPPQLGYAVSDENLTLGKKAELQVSNNAGEDTTEVNTDPFPETWLAIQPSLSLALPSSE 394

Query: 235 PVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGK-KQRPPGPLFSSSDPLPA 293
                      ++  K Q  LG +A   S  E +S A    K    P  P  S S+ LP 
Sbjct: 395 TDLTQGANPQLENLRKMQKSLGPLASPQSTGEATSVAHSPLKTPSLPTPPGCSQSELLPG 454

Query: 294 TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDG 353
           TS  S+ +A    + P   T    D     + S    +   P P        +LL  V  
Sbjct: 455 TSPDSKPTATFILLTPTSPTLPVTDTTWPPSTSQADRSPMPPDPPAPPTIQSTLLGMVSS 514

Query: 354 GPSHFLASATAAARA------------QRSEVRYNQRSQISRTRSCLKRNASSSSHSSTE 401
             SH  ASA   A +              SE+  +  S+IS T +     +S SS S+ +
Sbjct: 515 PTSHLSASAPPDATSAHLMLKPILGPLHNSEIGSSSYSRISVTAAA----SSISSLSTIQ 570

Query: 402 G--LPELKRRRG---PASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAP 456
           G   P  K   G   P  +   +A  SSK        A +       K        TLA 
Sbjct: 571 GTLTPTFKPIFGSIDPLKTTPMIAPFSSKQTPPPFTHASTHHFHGLVKATSVVMSTTLA- 629

Query: 457 RGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSL-------------ATGASRG 503
              + +    +P ++  +     A+ +   S PS   + L             ATG    
Sbjct: 630 --STSKDSVFKPPLDFGVVNVTSAVGNTY-SVPSTCDTFLLGTAQAFRADFTPATGFIFP 686

Query: 504 P------PVSKAPTMDAQ--------QDRPKSQDCLGLLAPLASAA-----ELPSTAPVS 544
           P      P     TM  Q          R  + +  G+ +PL ++A      L ST  +S
Sbjct: 687 PHHHPTIPTVHTVTMFTQVLSSVVQISPRSSTANFRGMGSPLPASALVSTNWLASTPSIS 746

Query: 545 ----------GKKHRPPGPLFSSSDPLP---ATSSHSRDSAQVTSM-------------- 577
                     G   RPP PL   ++P P   AT+   +  +Q   M              
Sbjct: 747 NLTPAITSPLGSSSRPPFPLSQGANPQPAFGATNGQKQGPSQPALMPSVSSSFLFGSSAV 806

Query: 578 -IPAPFTAASRDAGMRRTRP--GTSAPAAAAAAPPPSTLNPTSG 618
            +P P    ++ A +  T+   G   P+A+ +  P ST +   G
Sbjct: 807 ALPTPMPTPAQPAFISTTQSALGCLTPSASTSQTPASTWSGIGG 850



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 13/163 (7%)

Query: 520 KSQDCLGLLAPLASAAELPSTAPVSGKKHR-PPGPLFSSSDPLPATSSHSRDSAQVTSMI 578
           K Q  LG LA   S  E  S A    K    P  P  S S+ LP TS  S+ +A    + 
Sbjct: 410 KMQKSLGPLASPQSTGEATSVAHSPLKTPSLPTPPGCSQSELLPGTSPDSKPTATFILLT 469

Query: 579 PAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPT-SGSLLNAVDEGPSHFLASATA 637
           P   T    D     T P +++ A  +  PP     PT   +LL  V    SH  ASA  
Sbjct: 470 PTSPTLPVTDT----TWPPSTSQADRSPMPPDPPAPPTIQSTLLGMVSSPTSHLSASAPP 525

Query: 638 AARARRSQVR-------YNQRSQTSRTRSCLKRNASSSSHSST 673
            A +    ++        ++   +S +R  +   ASS S  ST
Sbjct: 526 DATSAHLMLKPILGPLHNSEIGSSSYSRISVTAAASSISSLST 568



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 722 PGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKA 781
           P  + A R   P    + P I S L            S P+  LS+ A   +    +   
Sbjct: 484 PSTSQADRSPMPPDPPAPPTIQSTLLG--------MVSSPTSHLSASAPPDATSAHLMLK 535

Query: 782 PTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSG 841
           P +    +          ++  A+A+ +SS + + G       P+F S DPL  T   + 
Sbjct: 536 PILGPLHNSEIGSSSYSRISVTAAASSISSLSTIQGTLTPTFKPIFGSIDPLKTTPMIAP 595

Query: 842 DSAQDTSLIPAPFTPAS 858
            S++ T   P PFT AS
Sbjct: 596 FSSKQT---PPPFTHAS 609


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 198/863 (22%), Positives = 309/863 (35%), Gaps = 146/863 (16%)

Query: 41   SPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGP 100
            S   P  GP  T   A  ++    Q + T     ++  + I+   +S       +Q    
Sbjct: 244  SSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRAS--STQQEISR 301

Query: 101  ASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPR--SQASRPRR 158
            ASS  Q T   S T  ED P+A SS      +A+ T   Q   PR  SP   +Q   PR 
Sbjct: 302  ASSTQQETSRASST-QEDTPRA-SSTQEDTPRASST---QWNTPRASSPSRSTQLDNPRT 356

Query: 159  RKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSR 218
                    +   P   P           +D   + +A+    N     E+   S  +   
Sbjct: 357  SSTQQDNPQTSFPTCTPQRENPRTPCVQQD---DPRASSP--NRTTQRENSRTSCAQRDN 411

Query: 219  PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQ 278
            P  + +S    A+   P     T  AQ+D P++          +S +  +   P +   Q
Sbjct: 412  PKASRTSSPNRATRDNP----RTSCAQRDNPRA----------SSPSRATRDNPTTSCAQ 457

Query: 279  RPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRD-----AGMRRTRSAPAAAAA 333
            R       +S P  AT  + R S             A RD     +  R TR  P  + A
Sbjct: 458  RDNPRASRTSSPNRATRDNPRTSC------------AQRDNPRASSPSRATRDNPTTSCA 505

Query: 334  APPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISR---TRSCLKR 390
                   + TS          P+         + AQR   R +  ++ +R   T SC +R
Sbjct: 506  QRDNPRASRTSS---------PNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQR 556

Query: 391  NASSSSHSSTEGLPELKRRRGPASSHCQLAH---SSSKTVSEDGPQAVSSGHTRCEKRAD 447
            +   +S +S+   P    R  P +S  Q  +   SS    + D P       T C +R +
Sbjct: 557  DNPRASRTSS---PNRATRDNPRTSCAQRDNPRASSPNRATRDNPT------TSCAQRDN 607

Query: 448  TAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVS 507
                +T +P     R+    P  + A     +A S   P+R +   S   + A R  P +
Sbjct: 608  PRASRTSSPN----RATRDNPRTSCAQRDNPRASS---PNRTTQQDSPRTSCARRDDPRA 660

Query: 508  KAPTMDAQQDRPKSQDCLGLLAPLASA------AELPSTAPVSGKKHRPPGPLFSSSDPL 561
             +P    QQ+ P++  C     P AS+       E P T+       R   P  ++    
Sbjct: 661  SSPNRTIQQENPRT-SCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQEN 719

Query: 562  PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAA--AAAAPPPSTL------ 613
            P TS   RD+ +          A+SR+  ++R  P TS        A+ P  T+      
Sbjct: 720  PRTSCARRDNPR----------ASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLR 769

Query: 614  -------NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYN---QRSQTSRTRSCLKR 663
                   NP + S   A  + P          + A+R  +R +   + +Q    R+C+++
Sbjct: 770  TSCTRQDNPRTSSPNRATRDNP--------RTSCAQRDNLRASSPIRATQQDNPRTCIQQ 821

Query: 664  NASSSSHSSTEGLQELKRRRGPASSHC-QLALSSSNTVSEDGPQAVSSRDTRCEKADTAP 722
            N   SS +  +  +    +R      C Q   + S +   D P   SS   +C       
Sbjct: 822  NIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSS---QC----CTQ 874

Query: 723  GQTLAPRGGSPRSQASRPRINSALHVEDKAISDCR-PSRPSHTLSSLATGASGGPPVSKA 781
             + L P      +Q + PR NS+ H  +K I     P RP+          S GP  S +
Sbjct: 875  KENLRPSSPHRSTQWNNPR-NSSPHRTNKDIPWASFPLRPTQ---------SDGPRTS-S 923

Query: 782  PTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSD---PLPATSS 838
            P+   Q + P +   + L        + SS  P    +H PP   F  +    P  ATSS
Sbjct: 924  PSRSKQSEVPWAS--IALRPTQGDRPQTSS--PSRPAQHDPPQSSFGPTQYNLPSRATSS 979

Query: 839  HSGDSAQDTSLIPAPFTPASRDA 861
                  Q TS   +P  PA+  A
Sbjct: 980  SHNPGHQSTSRTSSPVYPAAYGA 1002



 Score = 37.0 bits (84), Expect = 0.082
 Identities = 172/770 (22%), Positives = 248/770 (32%), Gaps = 99/770 (12%)

Query: 118  DRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPR--SQASRPR----RRKIPLLPSRRGEP 171
            D P+A S   T  ++   T+  Q   PR  SP   +Q   PR    RR  P   SR    
Sbjct: 680  DNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTI 739

Query: 172  LMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSH-TLSSLATGA 230
                P      R         +    + + ++   +D      R S P+  T  +  T  
Sbjct: 740  QRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNP----RTSSPNRATRDNPRTSC 795

Query: 231  SGGPPV-SKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK--------QRPP 281
            +    + + +P    QQD P++  C+    P +S+ +  +      K+        QR  
Sbjct: 796  AQRDNLRASSPIRATQQDNPRT--CIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDR 853

Query: 282  GPLFSSSDPLPATSSHSRDSAQVTSMIPA-PFTAAS----RDAGMRRT-RSAPAAAAAAP 335
               FS     P TSS S+   Q  ++ P+ P  +      R++   RT +  P A+    
Sbjct: 854  TQSFSFQRDNPGTSS-SQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLR 912

Query: 336  PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSS 395
            P  +  P + S        PS    S    A       + ++    S +R        SS
Sbjct: 913  PTQSDGPRTSS--------PSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSS 964

Query: 396  SHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAP---GQ 452
               +   LP     R  +SSH     S+S+T S   P A  +  T  E          G 
Sbjct: 965  FGPTQYNLPS----RATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH 1020

Query: 453  TLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSR-PSHTLSSLATGASRGPPVSKAP- 510
              APR  SP       H       E +A     P   P +   ++  G    P  S  P 
Sbjct: 1021 RDAPRASSPPRYLQ--HDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPR 1078

Query: 511  ------------TMDAQ-QDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSS 557
                        T DA+ Q +    + L L AP+         A    ++   P  LF  
Sbjct: 1079 HTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQD 1138

Query: 558  SDPLPATSSHS----RDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTL 613
               LP  S+ S     DS      IP P     RDA      P  S+P   A  P     
Sbjct: 1139 ---LPRASTESLVPSMDSLHECPHIPTPVCIGHRDA------PSFSSPPRQAPEPSLFFQ 1189

Query: 614  NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSST 673
            +P   S+           LA +T +     S V   Q     R        ASS      
Sbjct: 1190 DPPGTSM---------ESLAPSTDSLHG--SPVLIPQVCIGHRDAP----RASSPPRHPP 1234

Query: 674  EGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSP 733
              L  L     P SS       S  +      +    R+     AD  P + LA R   P
Sbjct: 1235 SDLAFLAPSPSPGSSG-----GSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGP 1289

Query: 734  RSQAS---RPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDR 790
            ++Q S   R        VE     + R S  +    +   G S  P   ++  +  Q   
Sbjct: 1290 QAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSP 1349

Query: 791  PKSQDCLGLVAPLASAAEVSSTAPVS--GKKHRPPGPLFSSSDPLPATSS 838
              S+    L A  A     S   P      + RP G       PLP  +S
Sbjct: 1350 APSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTS 1399



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 90/422 (21%), Positives = 156/422 (36%), Gaps = 52/422 (12%)

Query: 395 SSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGH-----TRCEKRADTA 449
           +S+SS+     ++R+   A S  +LA    +   E GP+A SS       TR     D A
Sbjct: 146 TSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE-GPRADSSQRAPSLLTRSPVGGDAA 204

Query: 450 PGQTLAPRGGSPRSQA---SRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
            GQ     GG  RS     +R    S L +E          R + T +S  T  S GP  
Sbjct: 205 -GQKKEDTGGGGRSAGQHWARLRGESGLSLERH--------RSTLTQASSMTPHS-GPRS 254

Query: 507 SKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSS 566
           + +    AQ+D           A  AS  E+P  +       R      S+   +   SS
Sbjct: 255 TTSQASPAQRDT----------AQAASTREIPRASSPHRITQRDTSRASSTQQEISRASS 304

Query: 567 HSRDSAQVTS-MIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVD 625
             +++++ +S     P  +++++   R +    + P A++ +      NP + S      
Sbjct: 305 TQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSS---TQQ 361

Query: 626 EGPSHFLASATAAAR-----------ARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTE 674
           + P     + T                R S      + + SRT SC +R+   +S +S+ 
Sbjct: 362 DNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRT-SCAQRDNPKASRTSSP 420

Query: 675 GLQELKRRRGPASSHCQLALSSSNTVSEDGPQ-AVSSRDTRCEKADTAPGQTLAPRGGSP 733
                   R   +       SS +  + D P  + + RD       ++P +       + 
Sbjct: 421 NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 480

Query: 734 RSQASRPRINS-ALHVEDKAISDC-RPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRP 791
            +Q   PR +S +    D   + C +   P  + +S    A+   P     T  AQ+D P
Sbjct: 481 CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP----RTSCAQRDNP 536

Query: 792 KS 793
           ++
Sbjct: 537 RA 538



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 74/315 (23%), Positives = 105/315 (33%), Gaps = 69/315 (21%)

Query: 116  SEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASR--------PRRRKIPLLPSR 167
            S+   Q  S  H   +  A    G   APR  SP  QA          PR     L+PS 
Sbjct: 1092 SDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSM 1151

Query: 168  RG--EPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSS 225
                E   +P P+ +G+R         +QA       +L  +D          P  ++ S
Sbjct: 1152 DSLHECPHIPTPVCIGHRDAPSFSSPPRQAP----EPSLFFQDP---------PGTSMES 1198

Query: 226  LA--TGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGP 283
            LA  T +  G PV         +D P++                      S   + PP  
Sbjct: 1199 LAPSTDSLHGSPVLIPQVCIGHRDAPRA----------------------SSPPRHPPSD 1236

Query: 284  L-FSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTL-N 341
            L F +  P P +S  SR SA      P   T  + +      R      A  PPP  L  
Sbjct: 1237 LAFLAPSPSPGSSGGSRGSA------PPGETRHNLE------REEYTVLADLPPPRRLAQ 1284

Query: 342  PTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTE 401
               G       GG +H      +  RA+  E  + Q  + S      +      S   ++
Sbjct: 1285 RQPGPQAQCSSGGRTH------SPGRAE-VERLFGQERRKSEAAGAFQAQDEGRSQQPSQ 1337

Query: 402  GLPELKRRR-GPASS 415
            G  +L RR+  PA S
Sbjct: 1338 GQSQLLRRQSSPAPS 1352


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 76.6 bits (187), Expect = 9e-14
 Identities = 193/883 (21%), Positives = 308/883 (34%), Gaps = 118/883 (13%)

Query: 83   SSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADT-APGQT 141
            S  S +G  PGL+   G  S     +LS S    +D P+  S G + C+ + +  A  QT
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRH---SLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492

Query: 142  LAPRGGSPRS-----QASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAA 196
              PR  SP S     +   P+R +     S   + +   P  +     ++++L ++  A+
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552

Query: 197  FQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGG--PPVSKAPTMDAQQDR----PK 250
             Q         +++ SD  P   + T + L   +  G  P V     +  ++ R    P+
Sbjct: 1553 PQ---------ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603

Query: 251  SQDCLGLVAPLASAAEVSSTAPV--------------SGKKQRPPGPLFSSS-DPLPATS 295
             +D     AP A +   SS  P               S  K R P P  SSS +  P   
Sbjct: 1604 VKD-KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662

Query: 296  SHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAA-------------------PP 336
              SR + + +   P P T +      R +RS+P     A                   PP
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722

Query: 337  PSTLNPTSGSLLNAVDGGPSHFLASA------TAAARAQ------RSEVRYNQRSQISRT 384
                +P+  S   A     S    SA      T + R +      R   R   RS+  +T
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782

Query: 385  RSCLKRNASSSSHSSTEGLPE-------LKRRRGPASSHCQL-AHSSSKTVSEDGPQAVS 436
            R+  +R+ S SS S++             +RRRG +  H +  A   S   S    +  S
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS 1842

Query: 437  SGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSL 496
                   KR+ +        R  S  S A+     S   +  +  S  R S  S   S  
Sbjct: 1843 RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902

Query: 497  ATGASRGPPVSKAPTMDAQQDR----PKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPG 552
             T  +R    S+A  +  ++ R    P ++       P         T PV+ ++ R   
Sbjct: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962

Query: 553  PLF------SSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAA 606
            P        S + P+    S SR S        +  +  +R     RT P T    + + 
Sbjct: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR-RSRSR 2021

Query: 607  APPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNAS 666
             PP       S + L       S    +    +R+R  +    +RS T    +  +R+AS
Sbjct: 2022 TPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS 2081

Query: 667  SSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEK--------A 718
             SS   +        R    S    +AL+SS       P    +   RC          +
Sbjct: 2082 GSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGS 2141

Query: 719  DTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPV 778
               P   L   GGS       PRI    H       +   SR +  L++++ G +  PP 
Sbjct: 2142 SRTPMSVLQQAGGS-MMDGPGPRIPD--HQRTSVPENHAQSRIALALTAISLGTARPPPS 2198

Query: 779  SKAPTMDAQQDR-PKSQDCLGL----VAPLASAAEVSSTAPVSGKKHRPPG---PLFSSS 830
              A  + A+  + P     + L     A LAS    +S A ++    R P     +  + 
Sbjct: 2199 MSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLAD 2258

Query: 831  DPLPATSSHSGDSAQDTSLIPA---------PFTPASRDAGVR 864
               PA ++    ++  T++ P+         P  PA   AG R
Sbjct: 2259 SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGAR 2301



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 194/834 (23%), Positives = 288/834 (34%), Gaps = 158/834 (18%)

Query: 73  SSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEK 132
           S S KR   S +  S       K++R  +++    +    ++ S D   +  +  +R   
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS 281

Query: 133 AADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLE 192
           AA       LA R  SP S               RRGE     P  E G   T+      
Sbjct: 282 AAAKTHTTALAGRSPSPAS--------------GRRGEG--DAPFSEPG--TTSTQRPSS 323

Query: 193 KQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGAS------------GG------- 233
            + A ++ +S    +DK   +   +RPS +    +TG              GG       
Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLAT 383

Query: 234 ---------PPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPL 284
                    PP   +PT D  +  PKS + L    P +S++E S  +P   K  R     
Sbjct: 384 TPLSQEPVNPPSEASPTRD--RSPPKSPEKL----PQSSSSESSPPSPQPTKVSRHASSS 437

Query: 285 FSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTS 344
             S  P PA  SH   S+  TS        A RD     T S     + +P         
Sbjct: 438 PESPKPAPAPGSHREISSSPTSK-NRSHGRAKRDKSHSHTPSRRMGRSRSP--------- 487

Query: 345 GSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLP 404
                              A A+  RS  R   +   SR+RS   R + S+        P
Sbjct: 488 -------------------ATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528

Query: 405 ELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQ 464
           +   RRG + S  +   S S+     G ++ S+   R   R+    G          RS+
Sbjct: 529 Q---RRGRSRSPQRPGWSRSRNTQRRG-RSRSARRGRSHSRSPATRG----------RSR 574

Query: 465 ASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDC 524
           +  P           A    R   P+   S   T A RG   S+ P     + R      
Sbjct: 575 SRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR------ 628

Query: 525 LGLLAPLASAAELPSTAPVSGK-KHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFT 583
               +P+   +   S A  SG+ + R P     S    PA    SR      S  PA   
Sbjct: 629 ----SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR------SRTPA--- 675

Query: 584 AASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARR 643
              R +G  R+R  T A    + +  P      S SL   V  G SH   S T   R R 
Sbjct: 676 ---RRSGRSRSR--TPARRGRSRSRTPRRGRSRSRSL---VRRGRSH---SRTPQRRGRS 724

Query: 644 SQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPAS--SHCQLALSSSNTVS 701
                +   + +++R+  +R+ S+SS    +     +R R  +S  S  +  LS   ++S
Sbjct: 725 G----SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS 780

Query: 702 EDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRP 761
              P       T   ++ +   Q  A     PR    R R +S+   + K+ +   PSR 
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR----RSRSSSSPPPKQKSKT---PSRQ 833

Query: 762 SHTLSSLATGASGGPPVSK----APTMDAQQDRPKSQDCL------GLVAPLASAAEVSS 811
           SH+ SS       G P  +    +P  + Q   P+ + C        L +   S    S 
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893

Query: 812 TAPVSGKKHRPP--GPLFSSSDP-------LPATSSHSGDSAQDTSLIPAPFTP 856
           ++P   K   PP   P  SSS          P   SHSG S+   S + +  TP
Sbjct: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 166/749 (22%), Positives = 276/749 (36%), Gaps = 92/749 (12%)

Query: 64   NQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAV 123
            ++TS  +   S ++ + ++   S +   P +++R     SR +  L   K      P A+
Sbjct: 1996 SRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRR-----SRSRTPLLPRKRSRSRSPLAI 2050

Query: 124  SS-GHTRCEKAADTAPGQTLAPRGGSPRSQA-SRPRRRKIPLLPSRRGEPLMMPPPLELG 181
                 +R  + A      T +P     RS + S   R +    P+ R       PP+ L 
Sbjct: 2051 RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL- 2109

Query: 182  YRVTAEDLHLEKQAAFQRINSALHVEDKAISD--CRPSRPSHTLSSLATGASG------G 233
                    +  + + F R + +    D+  S     P   S T  S+   A G      G
Sbjct: 2110 --------NSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPG 2161

Query: 234  PPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPA 293
            P +         ++  +S+  L L A     A    +   +G   R    +     P+P 
Sbjct: 2162 PRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR----MSQVPAPVPL 2217

Query: 294  TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTR----------SAPAAAAAAPPPSTLNPT 343
             S  +  +A + S IPA   AA   A  R               PAAAAA    S     
Sbjct: 2218 MSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAV 2277

Query: 344  SGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASS-SSHSSTEG 402
            + S +N  D       A   A AR   +       + +S T S     A++  S S T  
Sbjct: 2278 APSAVNLADPRTPTAPAVNLAGARTPAA------LAALSLTGSGTPPTAANYPSSSRTPQ 2331

Query: 403  LPELKRRRGPASSHCQ--LAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTL-APRGG 459
             P      GP S+H    +  + S+T +   P +++S      + A    G  L +PR  
Sbjct: 2332 APASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA-----RMAPALSGANLTSPR-- 2384

Query: 460  SPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPT---MDAQQ 516
             P S   R    ++  + D+A S   PS PS +  +     S    + +AP+   +   Q
Sbjct: 2385 VPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ 2444

Query: 517  DRPKS---------QDCL-GLLAPLASAAELPS----TAPVSGKKHRP----PGPLFSSS 558
            D+P+S           CL     P+A +  L S    T   S   H      P P    S
Sbjct: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504

Query: 559  DP-LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTS 617
            D   P  S+ ++  + + ++ PA    +S  +    +   +S+ ++++++   S+ + + 
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564

Query: 618  GSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQ 677
            GS L    E     + S T A +    + R  + +   R R     ++SSSS SS+    
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624

Query: 678  ELKRRRGPASSHCQLALSSSNTVS----EDGPQAVSSRDTRCEKADTAPGQTLAPRGGSP 733
                    +SS    + SSS++ S    + GPQA+             P     P  G  
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK-----------PASPKKPPPGER 2673

Query: 734  RSQASRPRINSALHVEDKAISDCRPSRPS 762
            RS++ R  I+S       + S     RPS
Sbjct: 2674 RSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 210/1018 (20%), Positives = 330/1018 (32%), Gaps = 173/1018 (16%)

Query: 2    PEQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEI 61
            PE     R        R+ PE+T  AR     L      +   P         H +S  +
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKAR-----LSRRSRSASSSPETRSRTPPRHRRSPSV 1730

Query: 62   RYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLK---QRRGPASSRCQLTLSYSKTVSED 118
               + ++ S   SS +R + SS  + T    G     + RG   SR +     ++T    
Sbjct: 1731 SSPEPAEKS--RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788

Query: 119  RPQAVSSGHTRCEKAADTAPGQTLAPRGGS----------PRSQASRPRRR---KIPLLP 165
                 S   +R  + + +    T   RGGS            S+ S  RRR   + P   
Sbjct: 1789 DRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848

Query: 166  SRRGEPLMMPPPLELGYRVTAEDLHLEKQA-----AFQRINSALHVEDKAISDCRPSRPS 220
             +R      P P +      +   H   ++     + +R  S      +  S  R S   
Sbjct: 1849 RKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTR 1908

Query: 221  HTLSSLATGASGGPPVSKAPTMDAQQDRPKS----QDCLGLVAPLASAAEVSSTAPVSGK 276
                S A+  S     S+ P +  ++ R ++    +       P+      S T PV+ +
Sbjct: 1909 RRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRR 1968

Query: 277  KQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPP 336
            + R      S + P+    S SR S        +  +  +R     RT       + +  
Sbjct: 1969 RSR------SRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2022

Query: 337  PSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRS---CLKRNAS 393
            P  +   S S    +    S    S  A  R  RS      R + S TRS     +R+AS
Sbjct: 2023 PPAIRRRSRSRTPLLPRKRSRS-RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS 2081

Query: 394  SSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAP-GQ 452
             SS   +        R    S    +A +SS+      P    +   RC       P G 
Sbjct: 2082 GSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGS 2141

Query: 453  TLAP-----RGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVS 507
            +  P     + G        P I    H       +   SR +  L++++ G +R PP  
Sbjct: 2142 SRTPMSVLQQAGGSMMDGPGPRIPD--HQRTSVPENHAQSRIALALTAISLGTARPPPSM 2199

Query: 508  KAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSH 567
             A  + A+  +  +   L  L   A AA L S  P +           + + P     + 
Sbjct: 2200 SAAGLAARMSQVPAPVPLMSLRT-APAANLASRIPAASAAAMNLASARTPAIPTAVNLAD 2258

Query: 568  SRDSAQVTSM-IPAPFTAASRDA-----GMRRTRP-----GTSAPAAAAA------APPP 610
            SR  A   +M + +P TA +  A         T P     G   PAA AA        PP
Sbjct: 2259 SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP 2318

Query: 611  STLN----------PTSGSLL---NAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRT 657
            +  N          P S +L+   +A    P +   S TAAA A  S          S  
Sbjct: 2319 TAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378

Query: 658  RSCLKRNASSS----SHSSTEGLQELKRRRGPASSHCQLALSSSNTVS------------ 701
                 R   S+    S  ++  L +  R R P S+  Q  ++S    S            
Sbjct: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS 2438

Query: 702  -----EDGPQA----VSSRDTRCEKADTAP-----------------------GQTLAPR 729
                 +D P++      S  +RC  A T P                       G    P 
Sbjct: 2439 LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498

Query: 730  GGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQD 789
             G P S    P  ++    +  A++  +P++   + SS ++ +S     S + +  +   
Sbjct: 2499 PGVPHSDVGEPPASTGAQ-QPSALAALQPAKERRSSSSSSSSSSSSSS-SSSSSSSSSSS 2556

Query: 790  RPKSQDCLGL---VAPLASAAEVSSTAPV---SGKKHRPPGPL----------------- 826
               S D  G    V P  +   V S  P    + ++ RPP P                  
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616

Query: 827  ----------FSSSDPLPATSSHSGDSAQDTS---------LIPAPFTPASRDAGVRR 865
                       SSS    ++SS S  S+  +S          +P P +P     G RR
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 97/438 (22%), Positives = 171/438 (39%), Gaps = 58/438 (13%)

Query: 116  SEDRPQAVSSGHTRCEKAAD-TAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMM 174
            S   PQA +S +    ++A  TAP      R  +  + AS    R  P L          
Sbjct: 2326 SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALS--------- 2376

Query: 175  PPPLELGYRVTAEDLHLEKQAAFQRINSALH--VEDKAISDCRPSRPSHTLSSLATGASG 232
                  G  +T+  + L   +A++R++      + D+A S   PS PS +  +     S 
Sbjct: 2377 ------GANLTSPRVPL---SAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP 2427

Query: 233  GPPVSKAPT---MDAQQDRPKS---------QDCL-GLVAPLASAAEVSSTAPVS----- 274
               + +AP+   +   QD+P+S           CL     P+A +  +SS A  +     
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487

Query: 275  ----GKKQRP-PGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPA 329
                G    P PG   S     PA++   + SA + ++ PA    +S  +    + S+ +
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA-LAALQPAKERRSSSSSSSSSSSSSSS 2546

Query: 330  AAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLK 389
            +++++   S+ + +S S  +++   P   L    +   A +  VR  +  + +  +   +
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRR 2606

Query: 390  RNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTA 449
             ++SSSS SS+            +SS    + SSS + S   P     G     K     
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK----- 2661

Query: 450  PGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPS-------HTLSSLATGASR 502
            P     P  G  RS++ R  I+S       + S     RPS          SS   G+ R
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721

Query: 503  GP-PVSKAPTMDAQQDRP 519
            G    S++P+   +++ P
Sbjct: 2722 GQRGDSRSPSHKRRRETP 2739



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 163/773 (21%), Positives = 260/773 (33%), Gaps = 160/773 (20%)

Query: 70   SWTSSSTKRNAISSSYSSTGGLPGLKQ--RRGPASSRCQLTLSYSKTVSEDRPQAVSSGH 127
            S T S  +R + S S +   G    +   RRG + SR       S++    R  A  SG 
Sbjct: 625  SRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS----RTPARRSGR 680

Query: 128  TRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAE 187
            +R    A     ++  PR G  RS++   R R     P RRG                  
Sbjct: 681  SRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRG------------------ 722

Query: 188  DLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQD 247
                       R  S+   ++K+ +  R SR            S   P  K   + +++ 
Sbjct: 723  -----------RSGSSSERKNKSRTSQRRSR------------SNSSPEMKKSRISSRRS 759

Query: 248  RPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSM 307
            R  S       + L+    +S ++P   +K + P          P  S       +  S 
Sbjct: 760  RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP----------PRRSRSGSSQPKAKSR 809

Query: 308  IPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAAR 367
             P            RR+RS     +++PPP   + T  S  +     P   + S T   +
Sbjct: 810  TPP-----------RRSRS-----SSSPPPKQKSKTP-SRQSHSSSSPHPKVKSGTPPRQ 852

Query: 368  AQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTV 427
               +  + N++S   + RSC + +            PELK R  P+   C          
Sbjct: 853  GSITSPQANEQSVTPQRRSCFESSPD----------PELKSRT-PSRHSCS--------- 892

Query: 428  SEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPS 487
                P+  SS   R      ++P     P+  +  S   R H  S+     +  S   P 
Sbjct: 893  GSSPPRVKSSTPPRQSPSRSSSP----QPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948

Query: 488  RPSHTLSSLATGASRGPP-----VSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAP 542
            R S ++S  +   SR  P      S +P    + + P  Q   G ++P            
Sbjct: 949  R-SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKV-------- 999

Query: 543  VSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPA 602
               K   PPGP  S S   P     S+D     S++ +   + S  AG++ + P      
Sbjct: 1000 ---KAQTPPGPSLSGSKS-PCPQEKSKD-----SLVQSCPGSLSLCAGVKSSTP------ 1044

Query: 603  AAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLK 662
                 P  S    +S  L       P H   S T++   R+S          S+T     
Sbjct: 1045 -----PGESYFGVSSLQLKGQSQTSPDH--RSDTSSPEVRQSHSESPSLQSKSQTSPKGG 1097

Query: 663  RNASSSSHSSTEGLQELKRRRG-------------PASSHCQLALSSSNTVSEDGPQAVS 709
            R+ SSS  +       +++ RG             P  S  Q   SS  TV  +     S
Sbjct: 1098 RSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQS 1157

Query: 710  SRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLA 769
                R E A++     L P+  +  S   +    S   V+D+  S         T     
Sbjct: 1158 ----RLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER 1213

Query: 770  TGASGGPPV----SKAPTMDAQQDR----PKSQDCLG-LVAPLASAAEVSSTA 813
            +GA   P      S  PT    ++      KS++  G +++ L+S  +  ST+
Sbjct: 1214 SGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTS 1266



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 166/778 (21%), Positives = 257/778 (33%), Gaps = 150/778 (19%)

Query: 18   RTVPEVTGDARSAFWPL---RDNGGLSPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSS 74
            RT P     +RS   P+   R      P + R    +T L  +      +  +    + S
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRS 2056

Query: 75   STKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAA 134
             T R A     S T   P +++R    SS              DR ++ +   TR    +
Sbjct: 2057 RTPRTA-RGKRSLTRSPPAIRRRSASGSS-------------SDRSRSATPPATRNHSGS 2102

Query: 135  DTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQ 194
             T P         S  S  SRP     PL   R   P M+ P   LG   T   + + +Q
Sbjct: 2103 RTPP----VALNSSRMSCFSRPSMSPTPL--DRCRSPGMLEP---LGSSRTP--MSVLQQ 2151

Query: 195  AAFQRINSAL-----HVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDR- 248
            A    ++        H       +   SR +  L++++ G +  PP   A  + A+  + 
Sbjct: 2152 AGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQV 2211

Query: 249  PKSQDCLGL----VAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQV 304
            P     + L     A LAS    +S A ++    R P      + P     + SR  A  
Sbjct: 2212 PAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTP------AIPTAVNLADSRTPAAA 2265

Query: 305  TSM-IPAPFTAASRDA---GMRRTRSAPA---------AAAAA-------PPPSTLN--- 341
             +M + +P TA +  A      RT +APA         AA AA        PP+  N   
Sbjct: 2266 AAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPS 2325

Query: 342  -------PTSGSLL---NAVDGGPSHFLASATAAARAQRSEVRYNQRSQIS--------- 382
                   P S +L+   +A    P +   S TAAA A  S         +S         
Sbjct: 2326 SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRV 2385

Query: 383  ------------------RTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSS- 423
                              R RS    +A S S  ++E  P    R G A S   L  +  
Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445

Query: 424  ------------------SKTVSEDGPQAVSSGHTRCE-KRADTAPGQTLAPRGGSPRSQ 464
                              ++T    G Q++SSG        A    G    P  G P S 
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505

Query: 465  ASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDC 524
               P  ++    +  A++  +P++   + SS ++ +S     S + +  +      S D 
Sbjct: 2506 VGEPPASTGAQ-QPSALAALQPAKERRSSSSSSSSSSSSSS-SSSSSSSSSSSGSSSSDS 2563

Query: 525  LGLLAPLASAAEL-------------------PSTAPVSGKKHRPPGPLFSSSDPLPATS 565
             G   P+     L                   P   P   K+        SSS    ++S
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623

Query: 566  SHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVD 625
            S S  S+  +S   +  +++S  +     +PG  A    A+   P      S S    +D
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPID 2683

Query: 626  EGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRR 683
                    S +   R R S     +  Q+S +    +R     S S +      KRRR
Sbjct: 2684 SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSH-----KRRR 2736



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 103/536 (19%), Positives = 174/536 (32%), Gaps = 105/536 (19%)

Query: 275 GKKQRPPG--PLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAA 332
           G K+  PG  P  + +  L   +    +  +    I   +   S     RR R A   A 
Sbjct: 106 GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP 165

Query: 333 AAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNA 392
             P P +L   S S              S T   + ++ +    +RS+ S  R   K+++
Sbjct: 166 EPPKPYSLVRESSSS------------RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS 213

Query: 393 SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQ 452
               H S                      S SK      P   S   ++ +KR  +    
Sbjct: 214 KKKKHRS---------------------ESESKKRKHRSPTPKSKRKSKDKKRKRS---- 248

Query: 453 TLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTM 512
               R  +P  ++ R H +++   +  + SD   SR     +   T A  G   S A   
Sbjct: 249 ----RSTTPAPKSRRAHRSTS--ADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGR 302

Query: 513 DAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSA 572
             + D P S+                   P +    RP  P  ++  P        +D  
Sbjct: 303 RGEGDAPFSE-------------------PGTTSTQRPSSPETATKQPSSPYEDKDKDKK 343

Query: 573 QVTSMIPAPF---------------TAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPT- 616
           + ++  P+P                  A R  G    +P  + P +     PPS  +PT 
Sbjct: 344 EKSATRPSPSPERSSTGPEPPAPTPLLAERHGG--SPQPLATTPLSQEPVNPPSEASPTR 401

Query: 617 --------------SGSLLNAVDEGPSHFLASATAAARARR-----SQVRYNQRSQTSRT 657
                         S S  +     P+     A+++  + +        R    S TS+ 
Sbjct: 402 DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN 461

Query: 658 RSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEK 717
           RS   R     SHS T   + + R R PA++  +   S S T ++ G     S   R  +
Sbjct: 462 RS-HGRAKRDKSHSHTPS-RRMGRSRSPATA--KRGRSRSRTPTKRGHSRSRSPQWRRSR 517

Query: 718 ADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGAS 773
           +    G++ +P+         RP  + + + + +  S       SH+ S    G S
Sbjct: 518 SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 79/377 (20%), Positives = 119/377 (31%), Gaps = 96/377 (25%)

Query: 545 GKKHRPPG--PLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPA 602
           G K   PG  P  + +  L   +    +  +    I   +   S     RR R    A  
Sbjct: 106 GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAR---EAKQ 162

Query: 603 AAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLK 662
            A   P P +L   S S              S T   + ++ +    +RS++S  R   K
Sbjct: 163 PAPEPPKPYSLVRESSSS------------RSPTPKQKKKKKKKDRGRRSESSSPRRERK 210

Query: 663 RNASSSSHSSTEGLQELKRRR----------------------GPASSHCQLALSSSNTV 700
           +++    H S    ++ K R                        P S     + S+ +  
Sbjct: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270

Query: 701 SED---------------------GPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASR 739
           S D                      P   S R    +   + PG T   R  SP +   +
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ 330

Query: 740 PRINSALHVEDKAISDCRPSRPSHTLSSLATGAS------------GG------------ 775
           P  +S    +DK   +   +RPS +    +TG              GG            
Sbjct: 331 P--SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQ 388

Query: 776 ----PPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSD 831
               PP   +PT D  +  PKS + L    P +S++E S  +P   K  R       S  
Sbjct: 389 EPVNPPSEASPTRD--RSPPKSPEKL----PQSSSSESSPPSPQPTKVSRHASSSPESPK 442

Query: 832 PLPATSSHSGDSAQDTS 848
           P PA  SH   S+  TS
Sbjct: 443 PAPAPGSHREISSSPTS 459



 Score = 33.5 bits (75), Expect = 0.91
 Identities = 81/383 (21%), Positives = 136/383 (35%), Gaps = 54/383 (14%)

Query: 74   SSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQA----VSSGHTR 129
            S T  +A S S  ++   P    R G A S+  L        ++D+P++      S  +R
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLP------PAQDQPRSPVPSAFSDQSR 2460

Query: 130  CEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPL--MMPPPLELGYRVTAE 187
            C  A  T    + +   G+  +  S        L     G P   +  PP   G +  + 
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520

Query: 188  DLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQD 247
               L  Q A +R +S+      + S    S  S + SS ++G+S     S+  ++  Q +
Sbjct: 2521 LAAL--QPAKERRSSS---SSSSSSSSSSSSSSSSSSSSSSGSSSSD--SEGSSLPVQPE 2573

Query: 248  RPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSM 307
                +      AP  +  E     P   K++R      SSS    ++SS S  S+  +S 
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633

Query: 308  IPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAAR 367
              +  +++S  +    + + P   A   P S   P  G                      
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE--------------------- 2672

Query: 368  AQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTV 427
                     +RS+  R      R++ S S+S  E     +RR  P  S      SSS+  
Sbjct: 2673 ---------RRSRSPRKPIDSLRDSRSLSYSPVE-----RRRPSPQPSPRDQQSSSSERG 2718

Query: 428  SEDGPQAVSSGHTRCEKRADTAP 450
            S  G +  S   +   +R   +P
Sbjct: 2719 SRRGQRGDSRSPSHKRRRETPSP 2741


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 150/658 (22%), Positives = 236/658 (35%), Gaps = 101/658 (15%)

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
            S K   P  P  +S+    +T+SH   S+  T+   A  T   R        S+P A A 
Sbjct: 1837 SSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 1896

Query: 334  APPPSTLNPTSGSL--LNAVDGGPS-----HFLASATAAARAQRSEVRYNQR----SQIS 382
             P P+  + TSG +    A    P      HF  S+TA+ R++ S   ++      S   
Sbjct: 1897 TPSPAR-STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP 1955

Query: 383  RTRSCLKRNA----SSSSHSSTEGLPELKRRRGPASSHCQLAHSS--------------- 423
             T S L        SS   ++T   P+     G  S     +HSS               
Sbjct: 1956 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSG-RSEESTASHSSQDATGTIVLPARSTT 2014

Query: 424  SKTVSEDGPQAVSSG--HTRCEKRADTAPG--QTLAPRGGSPRSQASRPHINSALHVEDK 479
            S  + E     +SSG   T     + T PG  +       SPRS A+     S       
Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 2074

Query: 480  AISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPS 539
              S    SRP  T ++    ++  P +S+  T       P S D    L P ++    PS
Sbjct: 2075 EESTTSHSRPGSTHTTAFPDSTTTPGLSRHST--TSHSSPGSTDT--TLLPASTTTSGPS 2130

Query: 540  -------TAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMR 592
                   ++P S      PG   + S    +T+ HS   +  T++ P   T++       
Sbjct: 2131 QESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST 2190

Query: 593  RTRPGTSAP-----AAAAAAP---------------------PPSTLN-PTSGSLLNAVD 625
            R    T +P      A++ +P                     PPST   P   S      
Sbjct: 2191 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 2250

Query: 626  EG---PSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRR 682
             G    +HF AS+T +  + +S + ++    +  T         SS+HS+T G  E    
Sbjct: 2251 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT--------PSSAHSTTSGRGESTTS 2302

Query: 683  R-GPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPR-----GGSPRSQ 736
            R  P S+       S+ T        +S   T    +  +P  TL+P      G    S 
Sbjct: 2303 RISPGSTEITTLPGSTTT------PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 2356

Query: 737  ASRPRINSALHVEDKAISDCRP--SRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQ 794
             SR +  S  H      S   P  S  S T+ S + G++      + PT   + + P + 
Sbjct: 2357 TSRSQPGST-HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTF 2415

Query: 795  DCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPA 852
                         E S+T+ ++ +    PG   S+   LPAT + + D  ++++  P+
Sbjct: 2416 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLT-TADLGEESTTFPS 2472



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 201/919 (21%), Positives = 324/919 (35%), Gaps = 133/919 (14%)

Query: 19   TVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWT--SSST 76
            T P ++ ++ + +   R +   + F   P    T +H +     +++ + T  T  +  +
Sbjct: 1292 TTPGLSEESTTVYSSSRGSTETTVF---PHSTTTSVHGEEPTTFHSRPASTHTTLFTEDS 1348

Query: 77   KRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADT 136
              + ++   ++  G P   Q   PA+    LT +     S   P +  S  T+   A  T
Sbjct: 1349 TTSGLTEESTAFPGSPASTQTGLPAT----LTTADLGEESTTFPSSSGSTGTKLSPARST 1404

Query: 137  APGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAA 196
              G      G S  S+ S P   +   LP     P +            + D  L     
Sbjct: 1405 TSGLV----GESTPSRLS-PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 1459

Query: 197  FQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLG 256
                +S +  E    S    S+P  T ++    ++    +S+ PT  +   +  ++  L 
Sbjct: 1460 ---TSSGVSEE----SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT-SHSSQGSTEATLS 1511

Query: 257  LVAPLASAAEVSST----APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPF 312
              +  AS+    ST    +P   +    P    +S     +T +HS   +  T++ PA  
Sbjct: 1512 PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 1571

Query: 313  TAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPS-----HFLASATAAAR 367
            T+A         +S P+++   P P         +       PS     HF AS+T   R
Sbjct: 1572 TSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR 1631

Query: 368  AQRSEVRYNQR----SQISRTRSCLK-------RNASSSSHSSTEGLPELKRRRG----- 411
            ++ S   ++      + +  TRS           +  SS  + T  LP      G     
Sbjct: 1632 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKS 1691

Query: 412  ------PASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTA-PGQTLAPRGGSPRSQ 464
                  P S    L+ +S  T S    +  ++ H+R      TA PG T  P G S  S 
Sbjct: 1692 TTFYSSPRSPDTTLSPAS--TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQEST 1748

Query: 465  ASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGAS--RGPPVSKAPTMDAQQDRPKSQ 522
            AS     S         +D   S  S T SSL   ++     P S   T+    D   + 
Sbjct: 1749 ASHSSPGS---------TDTTLSPGSTTASSLGPESTTFHSSPGSTETTL--LPDNTTAS 1797

Query: 523  DCLGLLAPLASAAELPST--APVSGKKHRPPGPLF----SSSDPLPA------------T 564
              L    P+ S+   P T  +P      +     F    SS D +PA            T
Sbjct: 1798 GLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELST 1857

Query: 565  SSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSL--LN 622
            +SH   S+  T+   A  T   R           S+P A A  P P+  + TSG +    
Sbjct: 1858 TSHGSPSSTPTTHFSASSTTLGRSEESTTVH---SSPVATATTPSPAR-STTSGLVEEST 1913

Query: 623  AVDEGPS-----HFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQ 677
            A    P      HF  S+TA+ R+  S+  ++  + T            SS  S+T  L 
Sbjct: 1914 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI-----------SSPPSTTSALV 1962

Query: 678  E--LKRRRGPASSHCQLALSSSNTV--SEDGPQAVSSRDT--------RCEKADTAPGQT 725
            E        P S+       SS T   SE+   + SS+D         R   +      T
Sbjct: 1963 EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 2022

Query: 726  LAPRGGSPRSQASRPRINSALHVEDKAIS-DCRPSRPSHTLSSLATGASGGPPVSKAPTM 784
             +P         + P   +   + +K+ +    P  P+ TLS  +T +SG   VS+  T 
Sbjct: 2023 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSG---VSEEST- 2078

Query: 785  DAQQDRPKSQDCLGL-----VAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSH 839
                 RP S              L+  +  S ++P S      P    +S     +T+SH
Sbjct: 2079 -TSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2137

Query: 840  SGDSAQDTSLIPAPFTPAS 858
            S   + DT+L P   T  S
Sbjct: 2138 SSPGSTDTALSPGSTTALS 2156



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 139/622 (22%), Positives = 223/622 (35%), Gaps = 83/622 (13%)

Query: 293  ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSL--LNA 350
            +T+ HS  S+  T+   A  T            S+P A A  PPP+  + TSG +    A
Sbjct: 445  STTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR-SATSGHVEESTA 503

Query: 351  VDGGPS-----HFLASATAAARAQRSEVRYNQRSQI-SRTRSCLKRNASSSSHSSTEGLP 404
                P      HF  S+T +  ++ S   +   +   S T S     A +S HSS  G  
Sbjct: 504  YHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL-GST 562

Query: 405  ELKRRRGPASSHCQLAHSSSKTVSED--GPQAVSSGHTRCEKRADTAPGQTLAPRGGSPR 462
            E    R  ++   +   S +   S D      + +G T      D+ P    +P      
Sbjct: 563  ETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTP----SPISSGSM 618

Query: 463  SQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQ 522
               + P   +   + +K+ +     R   T    A+  S G  VS+  T      RP S 
Sbjct: 619  ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG--VSEEST--TSHSRPGST 674

Query: 523  DCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSS---------HSRDSAQ 573
                       +  +P  +  S   H  PGP  ++  P   T+S         HSR  + 
Sbjct: 675  H----TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 730

Query: 574  VTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLA 633
             T+++P   TA    +G+       S P  ++   P +TL+P +GS     +    H   
Sbjct: 731  ETTLLPDNTTA----SGLLE----ASMPVHSSTRSPHTTLSP-AGSTTRQGESTTFHSWP 781

Query: 634  SATAAARARRSQV-RYNQRSQTSRTRSCLKRNASSSSHSSTEGL-QELKRRRGPASSHCQ 691
            S+     A  +    + + S TS            S+ S+T GL +E         S   
Sbjct: 782  SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 841

Query: 692  LALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDK 751
            +    S+T S  G ++ +S  +      +AP  T A     P S  S P   +  H  D 
Sbjct: 842  MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA-LVEEPTSYHSSPGSTATTHFPDS 900

Query: 752  AISDCRPSR----------------PSHTLSSLATGASGGPPVSK----------APTMD 785
            + +  R                   P+ + +S+  G S   P+S           + T  
Sbjct: 901  STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 960

Query: 786  AQQDR-------PKS-QDCLGLVAPLASAAEVSSTAPVS--GKKHRPPGPLFSSSDPLP- 834
               +R       P+S    L   +  +S     ST   S  G  H    P  +++  L  
Sbjct: 961  GLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSR 1020

Query: 835  -ATSSHSGDSAQDTSLIPAPFT 855
             +T+SHS   + DT+L+PA  T
Sbjct: 1021 HSTTSHSSPGSTDTTLLPASTT 1042



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 146/656 (22%), Positives = 233/656 (35%), Gaps = 97/656 (14%)

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
            + K   P  P  +S+    +T+SH   S+  T+   A  T   R        S+P A A 
Sbjct: 3394 NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 3453

Query: 334  APPPSTLNPTSGSLLNAVDGGPS-------HFLASATAAARAQRSEVRYNQR----SQIS 382
             P P+  + TSG +  +     S       HF  S T + R + S   ++      S   
Sbjct: 3454 TPSPAR-STTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP 3512

Query: 383  RTRSCLKRNA----SSSSHSSTEGLPELKRRRGPASSHCQLAHSS--------------- 423
             T S L        SS   ++T   P+     G  S     +HSS               
Sbjct: 3513 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSG-RSEESTASHSSQDATGTIVLPARSTT 3571

Query: 424  SKTVSEDGPQAVSSG--HTRCEKRADTAPG--QTLAPRGGSPRSQASRPHINSALHVEDK 479
            S  + E     +SSG   T     + T PG  +       SPRS A+     S       
Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 3631

Query: 480  AISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPL---ASAAE 536
              S    SRP  T ++    ++  P +S+  T       P S D   L A      S+ E
Sbjct: 3632 EESTTSHSRPGSTHTTAFPDSTTTPGLSRHST--TSHSSPGSTDTTLLPASTTTSGSSQE 3689

Query: 537  LPSTAPVSGKKHR--PPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRT 594
              ++   SG       PG   + S    +T+ HS   +  T++ P   T++       R 
Sbjct: 3690 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 3749

Query: 595  RPGTSAP-----AAAAAAP---------------------PPSTLN-PTSGSLLNAVDEG 627
               T +P      A++ +P                     PPST   P   S       G
Sbjct: 3750 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 3809

Query: 628  ---PSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRR- 683
                +HF AS+T +  + +S + ++    +  T         SS+HS+T G  E    R 
Sbjct: 3810 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTT--------PSSAHSTTSGRGESTTSRI 3861

Query: 684  GPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPR-----GGSPRSQAS 738
             P S+       S+ T        +S   T    +  +P  TL+P      G    S  S
Sbjct: 3862 SPGSTEITTLPGSTTT------PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 3915

Query: 739  RPRINSALHVEDKAISDCRP--SRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDC 796
            R +  S  H      S   P  S  S T+ S + G++      ++ T   +++ P +   
Sbjct: 3916 RSQPGST-HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHS 3974

Query: 797  LGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPA 852
                       E S+T+ ++ +    PG   S+   LPAT + + D  ++++  P+
Sbjct: 3975 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLT-TADLGEESTTFPS 4029



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 166/730 (22%), Positives = 257/730 (35%), Gaps = 117/730 (16%)

Query: 207  EDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAE 266
            E+ + S  +P     T    +T  SG   +S+ PT  +   +  ++  L   +  AS+  
Sbjct: 3023 EESSTSHSQPGSTHTTAFPDSTTTSG---LSQEPTA-SHSSQGSTEATLSPGSTTASSLG 3078

Query: 267  VSST----APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMR 322
              ST    +P   +    P    +S     +T +HS   +  T++ PA  T+A       
Sbjct: 3079 QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 3138

Query: 323  RTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPS-----HFLASATAAARAQRSEVRYNQ 377
              +S P+++   P P         +       PS     HF AS+T   R++ S   ++ 
Sbjct: 3139 TFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 3198

Query: 378  R----SQISRTRSCLK-------RNASSSSHSSTEGLPELKRRRG-----------PASS 415
                 + +  TRS           +  SS  + T  LP      G           P S 
Sbjct: 3199 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 3258

Query: 416  HCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTA-PGQTLAPRGGSPRSQASRPHINSAL 474
               L+ +S  T S    +  ++ H+R      TA PG T  P G S  S AS     S  
Sbjct: 3259 DTTLSPAS--TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQESTASHSSPGS-- 3313

Query: 475  HVEDKAISDCRPSRPSHTLSSL---ATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPL 531
                   +D   S  S T SSL   +T    GP  ++   +    D   +   L    P+
Sbjct: 3314 -------TDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLP---DNTTASGLLEASTPV 3363

Query: 532  ASAAELPST--APVSGKKHRPPGPLF----SSSDPLPA------------TSSHSRDSAQ 573
             S+   P T  +P      +     F    +S D  PA            T+SH   S+ 
Sbjct: 3364 HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSST 3423

Query: 574  VTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPS---- 629
             T+   A  T   R           S+P A A  P P+  + TSG +  +     S    
Sbjct: 3424 PTTHFSASSTTLGRSEESTTVH---SSPVATATTPSPAR-STTSGLVEESTTYHSSPGST 3479

Query: 630  ---HFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQE--LKRRRG 684
               HF  S T + R   S   ++  + T            SS+ S+T  L E        
Sbjct: 3480 QTMHFPESDTTSGRGEESTTSHSSTTHTI-----------SSAPSTTSALVEEPTSYHSS 3528

Query: 685  PASSHCQLALSSSNTV--SEDGPQAVSSRDT--------RCEKADTAPGQTLAPRGGSPR 734
            P S+       SS T   SE+   + SS+D         R   +      T +P      
Sbjct: 3529 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 3588

Query: 735  SQASRPRINSALHVEDKAIS-DCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKS 793
               + P   +   + +K+ +    P  P+ TLS  +T +SG   VS+  T      RP S
Sbjct: 3589 ETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSG---VSEEST--TSHSRPGS 3643

Query: 794  QDCLGL-----VAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTS 848
                          L+  +  S ++P S      P    +S     +T+SHS   + DT+
Sbjct: 3644 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTA 3703

Query: 849  LIPAPFTPAS 858
            L P   T  S
Sbjct: 3704 LSPGSTTALS 3713



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 153/668 (22%), Positives = 232/668 (34%), Gaps = 143/668 (21%)

Query: 217  SRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGK 276
            SRP  T ++   G++  P VS+  T  A    P S D    ++P ++ A  SS  P S  
Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQEST--ASHSSPGSTDTT--LSPGSTTA--SSLGPESTT 3334

Query: 277  KQRPPGPLFSSSDPLPATSS---------HSRDSAQVTSMIPAPFTAASRDAGMRRTRSA 327
                PG   ++  P   T+S         HS   +  T++ PA  T  +R       +S 
Sbjct: 3335 FHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGST--TRQGESTTFQSW 3392

Query: 328  PAAAAAAPPPSTLNPTSGSLLNAVDGGPS-----HFLASATAAARAQRSEVRYNQRSQIS 382
            P +    P P T       L     G PS     HF AS+T   R++ S   ++     +
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452

Query: 383  RTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAH-SSSKTVSEDGPQAVSSGHTR 441
             T         S + S+T GL E       +    Q  H   S T S  G ++ +S H+ 
Sbjct: 3453 TT--------PSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS-HSS 3503

Query: 442  CEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGAS 501
                  +AP  T A     P S  S P   +  H  D               SS  +G S
Sbjct: 3504 TTHTISSAPSTTSA-LVEEPTSYHSSPGSTATTHFPD---------------SSTTSGRS 3547

Query: 502  RGPPVSKAPTMDAQQDRPKSQDCLG-LLAPLASAAEL----PSTAPVSGKKHRP---PGP 553
                 S +           SQD  G ++ P  S   +     +T+P+S         PG 
Sbjct: 3548 EESTASHS-----------SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 3596

Query: 554  LFSSSDPLPATSSHSRDSAQVTSMIPAPFTAA--SRDAGMRRTRPGTSAPAA---AAAAP 608
              +      +T+ HS   +  T++ PA  T++  S ++    +RPG++   A   +   P
Sbjct: 3597 TTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP 3656

Query: 609  PPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSS 668
              S  + TS S   + D   +   AS T +  ++ S   ++    T    S     A S 
Sbjct: 3657 GLSRHSTTSHSSPGSTDT--TLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSF 3714

Query: 669  SHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAP 728
               ST           P S+H  L   S+ +        +    TR   +  +P  TL+P
Sbjct: 3715 GQESTTF------HSSPGSTHTTLFPDSTTS------SGIVEASTRVHSSTGSPRTTLSP 3762

Query: 729  RGG-SPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQ 787
                SP  Q       S       A +   PS PS                         
Sbjct: 3763 ASSTSPGLQGE-----STAFQTHPASTHTTPSPPS------------------------- 3792

Query: 788  QDRPKSQDCLGLVAPLASAAEVSSTAPV--SGKKHRPPGPLFSSSDPLPATSSHSGDSAQ 845
                                  ++TAPV  S   HR PG   + +   PA+S+ SG S +
Sbjct: 3793 ----------------------TATAPVEESTTYHRSPGS--TPTTHFPASSTTSGHSEK 3828

Query: 846  DTSLIPAP 853
             T    +P
Sbjct: 3829 STIFHSSP 3836



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 132/613 (21%), Positives = 223/613 (36%), Gaps = 46/613 (7%)

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
            S K  RP  P  +S+   P+T+SH   S+  T+ I A  T +          S+P +   
Sbjct: 782  SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 841

Query: 334  AP-PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNA 392
               P S      G          +H ++SA +   A   E   +  S    T +    ++
Sbjct: 842  MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGSTATTHFPDS 900

Query: 393  SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSG--HTRCEKRADTAP 450
            S++S  S E       +    +       ++S  + E     +SSG   T     + T P
Sbjct: 901  STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 960

Query: 451  GQTLAPRG----GSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
            G  L+ R      SPRS A+     S         S    SRP  T ++    ++  P +
Sbjct: 961  G--LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 1018

Query: 507  SKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHR-------PPGPLFSSSD 559
            S+  T       P S D    L P ++    PS    +             PG   + S 
Sbjct: 1019 SRHST--TSHSSPGSTDT--TLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSF 1074

Query: 560  PLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGS 619
               +T+ HS   +  T++ P   T++       R    T +P    +  P S+ +P    
Sbjct: 1075 GQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS--PASSTSPGLQG 1132

Query: 620  LLNAVDEGP--SHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQ 677
               A    P  +H   S  + A A   +     RS  S   +    ++++S HS    + 
Sbjct: 1133 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 1192

Query: 678  ELKRRRG---PASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRG--GS 732
                      P+S+H   +    +T S   P   S+  T    + T PG + A      S
Sbjct: 1193 HSSPDASGTTPSSAHSTTSGRGESTTSRISPG--STEITTLPGSTTTPGLSEASTTFYSS 1250

Query: 733  PRSQAS--RPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDR 790
            PRS  +   P   ++L V ++  S    S+P  T S+++  ++  P +S+  T      R
Sbjct: 1251 PRSPTTTLSPASMTSLGVGEE--STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSR 1308

Query: 791  PKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLI 850
              ++     V P ++   V    P +        P  + +      S+ SG + + T+  
Sbjct: 1309 GSTET---TVFPHSTTTSVHGEEPTTFHSR----PASTHTTLFTEDSTTSGLTEESTAF- 1360

Query: 851  PAPFTPASRDAGV 863
              P +PAS   G+
Sbjct: 1361 --PGSPASTQTGL 1371



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 154/735 (20%), Positives = 252/735 (34%), Gaps = 134/735 (18%)

Query: 224  SSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGP 283
            SS A+G S     S + T       P +   L +  P +  +   STA         P  
Sbjct: 1930 SSTASGRSEESRTSHSSTTHTISSPPSTTSAL-VEEPTSYHSSPGSTATTHF-----PDS 1983

Query: 284  LFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA----APPPST 339
              +S     +T+SHS   A  T ++PA  T +     +  + ++P ++ +    A P ST
Sbjct: 1984 STTSGRSEESTASHSSQDATGTIVLPARSTTSVL---LGESTTSPISSGSMETTALPGST 2040

Query: 340  LNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSS 399
              P            P    + AT  + A  +    ++ S  S +R       +    ++
Sbjct: 2041 TTPGLSEKSTTFHSSPR---SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 2097

Query: 400  TEGLPE--LKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTA--PGQTLA 455
            T GL          P S+   L  +S+ T    GP   S+         DTA  PG T A
Sbjct: 2098 TPGLSRHSTTSHSSPGSTDTTLLPASTTT---SGPSQESTTSHSSPGSTDTALSPGSTTA 2154

Query: 456  PRGGSPRSQA-SRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASR---GPPVSKAPT 511
               G   +   S P         D   S       +   SS  TG+ R    P  S +P 
Sbjct: 2155 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS--TGSPRTTLSPASSTSPG 2212

Query: 512  MDAQQDRPKSQDCLGLLAPLASAAELPSTAPV--SGKKHRPPGPLFSSSDPLPATSSHSR 569
            +  +    ++        P   +    +TAPV  S   HR PG   + +   PA+S+ S 
Sbjct: 2213 LQGESTAFQTHPASTHTTPSPPST---ATAPVEESTTYHRSPGS--TPTTHFPASSTTSG 2267

Query: 570  DSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLN-AVDEGP 628
             S + T    +P  + +  +    T  G      +  +P  + +    GS     + E  
Sbjct: 2268 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS 2327

Query: 629  SHFLAS----ATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELK---- 680
            + F +S     T  + A  + +   + S TSR++     +  S + ++T GL E      
Sbjct: 2328 TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY 2387

Query: 681  --------------------RRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADT 720
                                R   P + H + A + +   +ED     S+     E++  
Sbjct: 2388 SSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED-----STTSGLTEESTA 2442

Query: 721  APGQTLAPRGGSPR-----------------SQASRPRINSALHVEDKAISDCRPSR--P 761
             PG   + + G P                  S ++   ++ A       + +  PSR  P
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSP 2502

Query: 762  SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSS-TAPVSGKKH 820
            S T ++   G+   P +S+  T       P+S D     A L+ A   SS  +  S   H
Sbjct: 2503 SSTETTTLPGSPTTPSLSEKST--TFYTSPRSPD-----ATLSPATTTSSGVSEESSTSH 2555

Query: 821  RPPGPLFSSSDP--------------------------LPA-----------TSSHSGDS 843
              PG   +++ P                          LPA           T+SHS   
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPG 2615

Query: 844  AQDTSLIPAPFTPAS 858
            + DT+L P   T  S
Sbjct: 2616 STDTALSPGSTTALS 2630



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 152/713 (21%), Positives = 239/713 (33%), Gaps = 111/713 (15%)

Query: 216  PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGL-----VAPLASAAEVSST 270
            P  P+ TLS  +T +SG   VS+  T      RP S              L+  +  S +
Sbjct: 3613 PRSPATTLSPASTTSSG---VSEEST--TSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 3667

Query: 271  APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAA 330
            +P S      P    +S     +T+SHS   +  T++ P   TA S         S+P +
Sbjct: 3668 SPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGS 3727

Query: 331  -----------------------AAAAPPPSTLNPTSG--------SLLNAVDGGPSHFL 359
                                   ++   P +TL+P S         S         +H  
Sbjct: 3728 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT 3787

Query: 360  ASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQL 419
             S  + A A   E     RS  S   +    ++++S HS    +         + +    
Sbjct: 3788 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI--FHSSPDASGTTPSS 3845

Query: 420  AHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPR--------GGSPRSQAS--RPH 469
            AHS++    E     +S G T       T PG T  P           SPRS  +   P 
Sbjct: 3846 AHSTTSGRGESTTSRISPGST----EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPA 3901

Query: 470  INSALHV-EDKAISDCRP-----------------SRPSHTLSSLATGASRGPPVSKAPT 511
              ++L V E+   S  +P                 S  S T+ S + G++      ++ T
Sbjct: 3902 SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTT 3961

Query: 512  MDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDS 571
               +++ P +              E  +T+ ++ +    PG   S+   LPAT + +   
Sbjct: 3962 TSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG 4021

Query: 572  AQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNP--TSGSLLNAVDEGPS 629
             + T+     F ++S   G + + P  S  +       PS L+P  T  + L      PS
Sbjct: 4022 EESTT-----FPSSSGSTGTKLS-PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 4075

Query: 630  HFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSH 689
                S T     R      +  + TS   S      SS+SHS             P S+H
Sbjct: 4076 LSEKSTTFYTSPRSPDATLSPATTTSSGVS----EESSTSHSQ------------PGSTH 4119

Query: 690  CQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPR-GGSPRSQASRPRINSALHV 748
                  S+ T         S       +A  +PG T A   G    +  S P       +
Sbjct: 4120 TTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLL 4179

Query: 749  EDKAISD--CRPSRPSH-TLSSLATGASGGPPVSKAPTMDAQ--QDRPKSQDCLGLVAPL 803
             D  I+      S P+H +  SL T  +     S     ++   Q  P S D      P 
Sbjct: 4180 PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTP-SPPS 4238

Query: 804  ASAAEVSSTAPVSGKKHRPPGPLFSSSDPL-----PATSSHSGDSAQDTSLIP 851
             +A  V  +     +    P   FS+S         +T+ HS   A  T+L P
Sbjct: 4239 TTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 4291



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 134/598 (22%), Positives = 202/598 (33%), Gaps = 137/598 (22%)

Query: 281  PGPLFSSSDPLP-ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAA--PPP 337
            P P  +++ P+  +T+ HSR S+  T+   A  T   R        S+P A   A  P  
Sbjct: 4234 PSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 4293

Query: 338  STLNPTSGS-LLNAVDGGPSHFLA---SATAAARAQRSEVRYNQRSQISRTRSCLKRNAS 393
            S  +   G    + +  G +   A   S T A  +++S   Y+       T S     +S
Sbjct: 4294 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 4353

Query: 394  SSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQT 453
              S  ST             +SH +                  S HT     + T PG +
Sbjct: 4354 GVSEEST-------------TSHSR----------------PGSMHTTAFPSSTTMPGVS 4384

Query: 454  LAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMD 513
                                   ++   S   P     TLS  +T AS     S  P   
Sbjct: 4385 -----------------------QESTASHSSPGSTDTTLSPGSTTAS-----SLGPEST 4416

Query: 514  AQQDRPKSQDCLGLLAPLASAAELPSTAPV---SGKKHRPPGPLFSSSDPLPATSSHSRD 570
                 P S +   L     ++  L ++ PV   +G  H    P  S++    +T+  S  
Sbjct: 4417 TFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 4476

Query: 571  SAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSH 630
            +++ T+  PAP T  S    +  T  G+          P ST  PT            +H
Sbjct: 4477 NSKDTT--PAPPTTTSAFVELSTTSHGS----------PSST--PT------------TH 4510

Query: 631  FLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGL-QELKRRRGPASSH 689
            F AS+T   R+  S   ++    T+ T         S + S+T GL +E         S 
Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATT--------PSPARSTTSGLVEESTTYHSSPGST 4562

Query: 690  CQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVE 749
              +    SNT S  G ++ +S  +      +AP  T A     P S  S P   +  H  
Sbjct: 4563 QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSA-LVEEPTSYHSSPGSTATTHFP 4621

Query: 750  DKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLG-LVAPLASAAE 808
            D               SS  +G S     S +           SQD  G +V P  S   
Sbjct: 4622 D---------------SSTTSGRSEESTASHS-----------SQDATGTIVLPARSTTS 4655

Query: 809  V----SSTAPVSGKKHRP---PGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPASR 859
            V    S+T+P+S         PG   +      +T+ HS  S+  T+   A  T   R
Sbjct: 4656 VLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGR 4713



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 142/673 (21%), Positives = 235/673 (34%), Gaps = 93/673 (13%)

Query: 219  PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSST---APVSG 275
            P+ + +S+  G     P+S   T       P S    GL       +E S+T   +P S 
Sbjct: 4291 PTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTAGL-------SEKSTTFYSSPRSP 4341

Query: 276  KKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPA---------PFTAASRDAGMRRTRS 326
                 P    SS     +T+SHSR  +  T+  P+           TA+    G   T  
Sbjct: 4342 DTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTL 4401

Query: 327  APAAAAAA---PPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISR 383
            +P +  A+   P  +T + + GS    +   P +  AS    A         +  + +S 
Sbjct: 4402 SPGSTTASSLGPESTTFHSSPGSTETTL--LPDNTTASGLLEASTPVHSSTGSPHTTLSP 4459

Query: 384  TRSCLKRNASSSSHS-------------STEGLPELKRRRGPASSHCQLAHSSSKTVSED 430
              S  ++  S++  S             +T    EL      + S     H S+ + +  
Sbjct: 4460 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 4519

Query: 431  GPQAVSSGHTRCEKRADTAPGQTLAPRGG---SPRSQASRPHINSALHVEDKAISDCRPS 487
              +  ++ H+     A T P    +   G      +  S P     +H  +   +  R  
Sbjct: 4520 RSEESTTVHSSPVATA-TTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGE 4578

Query: 488  RPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASA-AELPSTAPVSGK 546
              + + SS     S  P      T  A  + P S       +P ++A    P ++  SG+
Sbjct: 4579 ESTTSHSSTTHTISSAP-----STTSALVEEPTSYHS----SPGSTATTHFPDSSTTSGR 4629

Query: 547  KHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAA 606
                            +T+SHS   A  T ++PA  T  S   G   T P  S+ +    
Sbjct: 4630 SEE-------------STASHSSQDATGTIVLPARST-TSVLLGESTTSP-ISSGSMETT 4674

Query: 607  APPPSTLNPTSGSLLNAVDEGPS-----HFLASATAAARARRSQVRYNQRSQTSRTRSCL 661
            A P ST  P            PS     HF AS+T   R+  S   ++    T+ T    
Sbjct: 4675 ALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT---- 4730

Query: 662  KRNASSSSHSSTEGL-QELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADT 720
                 S + S+T GL +E         S   +    S+T S    ++ +S  +      +
Sbjct: 4731 ----PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 4786

Query: 721  APGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSK 780
             P  T A     P S  S P   +  H  + + +  R    + + SS  T  +G  P+  
Sbjct: 4787 PPSTTSA-LVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDT--NGITPLPA 4843

Query: 781  APTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDP----LPAT 836
              T   +     ++     ++P +    ++STA   G   +      SS  P     PA+
Sbjct: 4844 HFTTSGR----IAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPAS 4899

Query: 837  SSHSGDSAQDTSL 849
             + S  S + TSL
Sbjct: 4900 MTSSSISGEPTSL 4912



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 143/661 (21%), Positives = 225/661 (34%), Gaps = 99/661 (14%)

Query: 268  SSTAPV--SGKKQRPPGPLFSSSDPLPATSS---------HSRDSAQVTSMIPAPFTAAS 316
            ++TAPV  S    R PG   ++  P  +T+S         HS   A  T+   A  T + 
Sbjct: 2710 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 2769

Query: 317  RDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYN 376
            R        S  +      P ST  P            P    +  T  + A  + +   
Sbjct: 2770 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR---SPTTTLSPASMTSLGVG 2826

Query: 377  QRSQISRTRSCLKRNASSSSHSSTEGLPELKRR----------------------RG--- 411
            + S  SR++     +  S + ++T GL E                          RG   
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886

Query: 412  ------PASSHCQLAHSSSKT--VSEDG------PQAVSSGHTRCEKRADTAPGQTLAPR 457
                  PAS+H  L    S T  ++E+       P +  +G       AD     T  P 
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 2946

Query: 458  GGSPRSQASRPHINSALHVEDKAISDCRPSR--PSHTLSSLATGASRGPPVSKAPTMDAQ 515
                      P    A       + +  PSR  PS T ++   G+   P +S+  T    
Sbjct: 2947 SSGSTGTTLSP----ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST--TF 3000

Query: 516  QDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDP---------LPATSS 566
               P+S D    L+P  + +     +  S   H  PG   +++ P            T+S
Sbjct: 3001 YTSPRSPDAT--LSPATTTSS--GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTAS 3056

Query: 567  HSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSG----SLLN 622
            HS   +   ++ P   TA+S   G + T   +S         P  T+  TSG    S   
Sbjct: 3057 HSSQGSTEATLSPGSTTASS--LGQQSTTFHSSPGDTETTLLPDDTI--TSGLVEASTPT 3112

Query: 623  AVDEGPSHFL---ASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQEL 679
                G  H     AS+T+A     S    +  S +  T S     A+    S+T   +  
Sbjct: 3113 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPS 3172

Query: 680  KRRRGPAS-SHCQLALSSSNTVSEDGPQAVSSR--DTRCEKADTAPGQTLAPRGGSPRSQ 736
                   S S   L  S  +T     P A  +    TR   +      T +P        
Sbjct: 3173 STPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET 3232

Query: 737  ASRPRINSALHVEDKAISD-CRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQD 795
             + P   +   + +K+ +    P  P  TLS  +T +SG   VS+  T      RP S  
Sbjct: 3233 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG---VSEEST--TSHSRPGSTH 3287

Query: 796  CLGL-----VAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLI 850
                     +  ++  +  S ++P S      PG   +SS    +T+ HSG  + +T+L+
Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLL 3347

Query: 851  P 851
            P
Sbjct: 3348 P 3348



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 181/908 (19%), Positives = 305/908 (33%), Gaps = 155/908 (17%)

Query: 5    DKDPRVQENPDDHRTVPEV---TGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEI 61
            +K      +PD   T P     T   R      R + G +     PG   T   +++S  
Sbjct: 2270 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2329

Query: 62   RYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKT--VSEDR 119
             Y+     + T S     ++     ST        R  P S+   ++ + + T  +SE+ 
Sbjct: 2330 FYSSPRSPTTTLSPASMTSLGVGEEST------TSRSQPGSTHSTVSPASTTTPGLSEES 2383

Query: 120  PQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMM----- 174
                SS     E         T + RG  P +  SRP      L         +      
Sbjct: 2384 TTVYSSSPGSTETTVFPRT-PTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 2442

Query: 175  ----PPPLELGYRVTAEDLHL-EKQAAFQR--------INSALHVEDKAISDCRPSR--P 219
                P   + G   T     L E+   F          ++ A       + +  PSR  P
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSP 2502

Query: 220  SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSS-TAPVSGKKQ 278
            S T ++   G+   P +S+  T       P+S D     A L+ A   SS  +  S    
Sbjct: 2503 SSTETTTLPGSPTTPSLSEKST--TFYTSPRSPD-----ATLSPATTTSSGVSEESSTSH 2555

Query: 279  RPPGPLFSSSDP---------LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPA 329
              PG   +++ P           +T+SHS   +  T+++PA  T +        + S+P 
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPG 2615

Query: 330  AAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLK 389
            +   A  P                       S TA +  Q S   +   S    T + L 
Sbjct: 2616 STDTALSP----------------------GSTTALSFGQESTTFH---SSPGSTHTTLF 2650

Query: 390  RNASSSSHSSTEGLPELKRR--RGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRAD 447
             ++++SS     G+ E   R      S    L+ +SS +    G       H        
Sbjct: 2651 PDSTTSS-----GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTP 2705

Query: 448  TAPGQTLAPRGGSP---RSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGP 504
            + P    AP   S    RS  S P  +        A S         T+   +  AS   
Sbjct: 2706 SPPSTATAPVEESTTYHRSPGSTPTTHF------PASSTTSGHSEKSTIFHSSPDASGTT 2759

Query: 505  PVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPAT 564
            P S   T   + +   S+                  +P S +    PG   +      +T
Sbjct: 2760 PSSAHSTTSGRGESTTSR-----------------ISPGSTEITTLPGSTTTPGLSEAST 2802

Query: 565  SSHSRDSAQVTSMIPAPFTA--ASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLN 622
            + +S   +  T++ PA  T+     ++   R++PG++    + A+     L+  S ++ +
Sbjct: 2803 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 2862

Query: 623  AVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRR 682
            +     S      T   R+  + VR  +   T  +R         +  S+T GL E    
Sbjct: 2863 S-----SPGSTETTVFPRSTTTSVR-GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 2916

Query: 683  RGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRI 742
               + +  Q  L ++ T ++ G ++     T    +  + G TL+P              
Sbjct: 2917 FPGSPASTQTGLPATLTTADLGEES-----TTFPSSSGSTGTTLSP-------------- 2957

Query: 743  NSALHVEDKAISDCRPSR--PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 800
              A       + +  PSR  PS T ++   G+   P +S+  T       P+S D     
Sbjct: 2958 --ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST--TFYTSPRSPD----- 3008

Query: 801  APLASAAEVSS-TAPVSGKKHRPPGPLFSSSDP---------LPATSSHSGDSAQDTSLI 850
            A L+ A   SS  +  S   H  PG   +++ P            T+SHS   + + +L 
Sbjct: 3009 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLS 3068

Query: 851  PAPFTPAS 858
            P   T +S
Sbjct: 3069 PGSTTASS 3076



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 148/678 (21%), Positives = 220/678 (32%), Gaps = 103/678 (15%)

Query: 205 HVEDKAISDCRPSR------PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 258
           H E+  +S   P        PSH+ +S+  G     P++ A +M+     P S    GL 
Sbjct: 220 HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA-SMETTA-LPGSTTTAGL- 276

Query: 259 APLASAAEVSST---APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAA 315
                 +E S+T   +P S  +   P    SS     +T+SHSR     T   P   T  
Sbjct: 277 ------SEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMP 330

Query: 316 SRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRY 375
                   + S P +      P T  P+S              L   +    +     + 
Sbjct: 331 GVSQESTASHSIPGSTDTTLSPGTTTPSS--------------LGPESTTFHSSPGYTKT 376

Query: 376 NQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAV 435
            +    + T   L+  AS+  HSST             S H  L+ SSS T  E  P   
Sbjct: 377 TRLPDNTTTSGLLE--ASTPVHSST------------GSPHTTLSPSSS-TTHEGEPTTF 421

Query: 436 SSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALH--VEDKAISDCRPSRPSHTL 493
            S  +   K    AP  T +       +  S P      H       +     S P H  
Sbjct: 422 QSWPS--SKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVH-- 477

Query: 494 SSLATGASRGPPVSKAPTMDAQQD-----RPKSQDCLGLLAPLASAAELPSTAPVSGKKH 548
           SS    A+  PP   A +   ++       P S   +       ++     +A   G   
Sbjct: 478 SSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTT 537

Query: 549 RPPGPLFSSSDPLPATSSHS----------RDSAQVTSMI-PAPFTAASRDAGMRRTRPG 597
                  S++  L  TS HS          RDS+ ++     +  + +S DA      P 
Sbjct: 538 HTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPA 597

Query: 598 TSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRT 657
            S P+       PS +  +SGS+      G      S T    + +S   Y+       T
Sbjct: 598 GSTPSVLVGDSTPSPI--SSGSMETTALPG------STTKPGLSEKSTTFYSSPRSPDTT 649

Query: 658 RSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEK 717
                  +S  S  ST           P S+H   A   S T+       +S   T    
Sbjct: 650 HLPASMTSSGVSEESTTS------HSRPGSTH-TTAFPGSTTM-----PGLSQESTASHS 697

Query: 718 ADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP 777
           +      TL+P  GS  + +  P   +            RP     TL    T ASG   
Sbjct: 698 SPGPTDTTLSP--GSTTASSLGPEYTT---------FHSRPGSTETTLLPDNTTASGLLE 746

Query: 778 VSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATS 837
            S  P   + +    +    G       +    S    S K  RP  P  +S+   P+T+
Sbjct: 747 AS-MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWP--SSKDTRPAPPTTTSAFVEPSTT 803

Query: 838 SHSGDSAQDTSLIPAPFT 855
           SH   S+  T+ I A  T
Sbjct: 804 SHGSPSSIPTTHISARST 821



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 125/619 (20%), Positives = 221/619 (35%), Gaps = 134/619 (21%)

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
            + K   P  P  +S+    +T+SH   S+  T+   A  T   R        S+P A A 
Sbjct: 4477 NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 4536

Query: 334  APPPSTLNPTSGSLLNAVDGGPS-------HFLASATAAARAQRSEVRYNQRSQISRTRS 386
             P P+  + TSG +  +     S       HF  S T + R + S   ++  +       
Sbjct: 4537 TPSPAR-STTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTT------- 4588

Query: 387  CLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRA 446
                +  SS+ S+T  L E      P S H                              
Sbjct: 4589 ----HTISSAPSTTSALVE-----EPTSYH------------------------------ 4609

Query: 447  DTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
             ++PG T         + + R   ++A H    A        P+ + +S+  G S   P+
Sbjct: 4610 -SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI--VLPARSTTSVLLGESTTSPI 4666

Query: 507  SKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVS---------GKKHRP----PGP 553
            S   +M+     P S    GL     +    PS+ P +         G+          P
Sbjct: 4667 SSG-SMETTA-LPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSP 4724

Query: 554  LFSSSDPLPA-----------TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGT---- 598
            + +++ P PA           T+ HS   +  T   P   TA+ R    R +   T    
Sbjct: 4725 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI 4784

Query: 599  SAPAAAAAA--PPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSR 656
            S+P +  +A    P++ + + GS+        +HF  S+T + R+  S   ++       
Sbjct: 4785 SSPPSTTSALVEEPTSYHSSPGSI------ATTHFPESSTTSGRSEESTASHSSPDTNGI 4838

Query: 657  TRSCLKRNASSSSHSSTEG--LQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTR 714
            T           +H +T G   +       P S    LA +++          +S++ T 
Sbjct: 4839 T--------PLPAHFTTSGRIAESTTFYISPGSMETTLASTATT-------PGLSAKSTI 4883

Query: 715  CEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASG 774
               +  +P QTL+P   +  S +  P   ++L+ +         +  +HT +  A+  + 
Sbjct: 4884 LYSSSRSPDQTLSPASMTSSSISGEP---TSLYSQ---------AESTHTTAFPASTTTS 4931

Query: 775  GPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLP 834
            G  +S+  T      +P S +    ++P   +   SS A      H  PG   S+    P
Sbjct: 4932 G--LSQEST--TFHSKPGSTET--TLSP--GSITTSSFAQEFTTPHSQPGSALSTVS--P 4981

Query: 835  ATSSHSGDSAQDTSLIPAP 853
            A+++  G S + T+   +P
Sbjct: 4982 ASTTVPGLSEESTTFYSSP 5000



 Score = 34.7 bits (78), Expect = 0.41
 Identities = 71/347 (20%), Positives = 126/347 (36%), Gaps = 89/347 (25%)

Query: 281  PGPLFSSSDPL--PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPP-- 336
            P P  S++  L   +T+ HS   +  T   P   TA+ R    R + S+     ++PP  
Sbjct: 4731 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 4790

Query: 337  -------PSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLK 389
                   P++ + + GS+        +HF  S+T + R++                    
Sbjct: 4791 TSALVEEPTSYHSSPGSI------ATTHFPESSTTSGRSEE------------------- 4825

Query: 390  RNASSSSHSS--TEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRAD 447
               S++SHSS  T G+        P  +H     ++S  ++E     +S G         
Sbjct: 4826 ---STASHSSPDTNGIT-------PLPAH----FTTSGRIAESTTFYISPGSME------ 4865

Query: 448  TAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVS 507
                 TLA    +P   A    + S+    D+ +S           +S+ + +  G P S
Sbjct: 4866 ----TTLASTATTPGLSAKSTILYSSSRSPDQTLSP----------ASMTSSSISGEPTS 4911

Query: 508  KAPTMDAQQDR--PKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATS 565
                 ++      P S    G    L+  +    + P S +    PG + +SS     T+
Sbjct: 4912 LYSQAESTHTTAFPASTTTSG----LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTT 4967

Query: 566  SHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPST 612
             HS+  + ++++ PA  T            PG S  +    + P ST
Sbjct: 4968 PHSQPGSALSTVSPASTTV-----------PGLSEESTTFYSSPGST 5003



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 32/142 (22%)

Query: 747 HVEDKAISDCRPSR------PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 800
           H E+  +S   P        PSH+ +S+  G     P++ A +M+     P S    GL 
Sbjct: 220 HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA-SMETTA-LPGSTTTAGLS 277

Query: 801 AP--------------LASAAEVSS-TAPVSGKKHRPPGPL----FSSSDPLP-----AT 836
                           L+ A   SS  +  S   H  PGP     F  S  +P     +T
Sbjct: 278 EKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQEST 337

Query: 837 SSHSGDSAQDTSLIPAPFTPAS 858
           +SHS   + DT+L P   TP+S
Sbjct: 338 ASHSIPGSTDTTLSPGTTTPSS 359


>gi|112421134 hypothetical protein LOC23742 [Homo sapiens]
          Length = 1156

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 146/687 (21%), Positives = 254/687 (36%), Gaps = 77/687 (11%)

Query: 3   EQDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIR 62
           ++D+DP   E  DD +  P  +G+A S        G ++ F   PGPL+ +++ + SE  
Sbjct: 161 KKDEDPVQIEGEDDEKRTPLSSGEASSTSRSQGTQGDVASFRCSPGPLEGNVYHKFSENS 220

Query: 63  YNQTSQTSWTSSSTKRNAISSSYSSTG-----GLPGLKQRRGPASS-RCQLTLS--YSKT 114
            ++ +Q S  SS  +  A+ S++S  G     G P       P  +  C L      ++ 
Sbjct: 221 MSEKAQASPASSCLEGPAMPSTHSQAGCARHLGKPDPDATAPPEPAVGCSLLQQKLAAEV 280

Query: 115 VSEDRPQA-------VSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIP---LL 164
           ++E+ P +       + SG    ++     P ++ AP    PR+  +RP +RK+    LL
Sbjct: 281 LNEEPPPSSLGLPIPLMSGKRMPDEKPFCIPPRSAAP----PRAARNRPCKRKMSIPLLL 336

Query: 165 PSRRGEPLM-----MPPPLELGYRVTAEDLH-LEKQAAFQRINSALHVEDKAISDCRPSR 218
           P     PL+     +PPP +L       DLH LEK   ++R +  L  + + +++   ++
Sbjct: 337 PLPPSLPLLWDRGELPPPAKLPCLSVEGDLHTLEKSPEYKRNSRILEDKTETMTNSSITQ 396

Query: 219 PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK- 277
           P+ + S         P  +    + A    P   D      PL       ST P   +K 
Sbjct: 397 PAPSFSQPVQTTDSLPLTTYTSQVSAPLPIPDLADL--ATGPLILPIPPLSTTPKMDEKI 454

Query: 278 --QRPPGPLFSSSDPLPATSSHSRD----------SAQVTSMIPAPFTAASRDAGMRRTR 325
               P  PL   +D +P     S +          +A +TS  P P  +++       TR
Sbjct: 455 AFTIPNSPLALPADLVPILGDQSNEKGGSYNSVVGAAPLTSDPPTP-PSSTPSFKPPVTR 513

Query: 326 SAPAAAAAAPPPS----TLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQI 381
            +P +     PP     TL P   +  + +   P +  +++  +     +      ++ +
Sbjct: 514 ESPISMCVDSPPPLSFLTLLPVPSTGTSVITSKPMN--STSVISTVTTNASAHLTSQTAV 571

Query: 382 SRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQL-AHSSSKTVSEDGPQAVSSGHT 440
                 +   A S     T  L         +  HC        KT     P      +T
Sbjct: 572 DPEVVNMDTTAPSQVVIFTSSLSSRVSSLPNSQIHCSAEQRHPGKTSVYTSPLPFIFHNT 631

Query: 441 RCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGA 500
                       T  P+  +P  Q  +  + SA       I    P   S  ++S +T +
Sbjct: 632 TPSFNQLFGKEATPQPKFEAPDGQPQKASLPSACVFLSLPI--IPPPDTSTLVNSASTAS 689

Query: 501 SRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDP 560
           S  PP+      +A    P S+  + L +   S   LP    + G  +  P         
Sbjct: 690 SSKPPIE----TNAMHTTPPSKAVI-LQSASVSKKYLPFYLGLPGSGNTQP--------- 735

Query: 561 LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPA--AAAAAPPPSTLNPTSG 618
                S +  S Q ++ +PA    A   A      PG +      A   P   T  P++ 
Sbjct: 736 -----SGNTASVQGSTSLPAQSVRAPATASNHPLNPGATPQPKFGAPDGPQQKTSLPSAH 790

Query: 619 SLLN---AVDEGPSHFLASATAAARAR 642
             L+    V    S  ++SA+AA+ ++
Sbjct: 791 DFLSLPIMVPPDTSTLVSSASAASLSK 817


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 140/624 (22%), Positives = 224/624 (35%), Gaps = 87/624 (13%)

Query: 293 ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSL--LNA 350
           +T+ HS  S+  T+   A  T            S+P A A  PPP+  + TSG +    A
Sbjct: 366 STTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR-SATSGHVEESTA 424

Query: 351 VDGGPS-----HFLASATAAARAQRSEVRYNQRSQI-SRTRSCLKRNASSSSHSSTEGLP 404
               P      HF  S+T +  ++ S   +   +   S T S     A +S HSS  G  
Sbjct: 425 YHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL-GST 483

Query: 405 ELKRRRGPASSHCQLAHSSSKTVSED--GPQAVSSGHTRCEKRADTAPGQTLAPRGGSPR 462
           E    R  ++   +   S +   S D      + +G T      D+ P    +P      
Sbjct: 484 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTP----SPISSGSM 539

Query: 463 SQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQ 522
              + P   +   + +K+ +     R   T    A+  S G  VS+  T      RP S 
Sbjct: 540 ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG--VSEEST--TSHSRPGST 595

Query: 523 DCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSS---------HSRDSAQ 573
                      +  +P  +  S   H  PGP  ++  P   T+S         HSR  + 
Sbjct: 596 H----TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 651

Query: 574 VTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLA 633
            T+++P   TA    +G+       S P  ++   P +TL+P +GS     +    H   
Sbjct: 652 ETTLLPDNTTA----SGLLE----ASMPVHSSTRSPHTTLSP-AGSTTRQGESTTFHSWP 702

Query: 634 SATAAARARRSQV-RYNQRSQTSRTRSCLKRNASSSSHSSTEGL-QELKRRRGPASSHCQ 691
           S+     A  +    + + S TS            S+ S+T GL +E         S   
Sbjct: 703 SSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 762

Query: 692 LALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDK 751
           +    S+T S  G ++ +S  +      +AP  T A     P S  S P   +  H  D 
Sbjct: 763 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA-LVEEPTSYHSSPGSTATTHFPDS 821

Query: 752 AISDCRPSR----------------PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQD 795
           + +  R                   P+ + +S+  G S   P+S   +M+     P S  
Sbjct: 822 STTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSG-SMETTA-LPGSTT 879

Query: 796 CLGL--------------VAPLASAAEVSS-TAPVSGKKHRPPGPLFSSSDP-------- 832
             GL                 L+ A+  SS  +  S   H  PG   +++ P        
Sbjct: 880 TPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 939

Query: 833 -LPATSSHSGDSAQDTSLIPAPFT 855
              +T+SHS   + DT+L+PA  T
Sbjct: 940 SRHSTTSHSSPGSTDTTLLPASTT 963



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 132/652 (20%), Positives = 217/652 (33%), Gaps = 92/652 (14%)

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
            S    RP  P  +S+   P+T+SH   S+  T+ I A  T +          S+P +   
Sbjct: 703  SSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 762

Query: 334  AP-PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNA 392
               P S      G          +H ++SA +   A   E   +  S    T +    ++
Sbjct: 763  MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGSTATTHFPDS 821

Query: 393  SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSG--HTRCEKRADTAP 450
            S++S  S E +     +    +       ++S  + E     +SSG   T     + T P
Sbjct: 822  STTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTP 881

Query: 451  GQTLAPRG----GSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
            G  L+ R      SPRS A+     S         S    SRP  T ++    ++  P +
Sbjct: 882  G--LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 939

Query: 507  SKAPTMDAQQDRPKSQDCLGLLAPLASAAEL---PSTAPVSGKKHRP------------- 550
            S+  T       P S D    L P ++   L   P+T+P+S                   
Sbjct: 940  SRHST--TSHSSPGSTDTT--LLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLS 995

Query: 551  ------------------PGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFT--AASRDAG 590
                              P    SS     +T+SHSR  +  T+  P   T    S+++ 
Sbjct: 996  EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1055

Query: 591  MRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQ 650
               + PG++    +  +   S+L P S +  +      +  L   T A+    +    + 
Sbjct: 1056 ASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 1115

Query: 651  RSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAV-- 708
             + + RT      + +    S+T       +   PA      A    +T S   P ++  
Sbjct: 1116 STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPT 1175

Query: 709  ------------SSRDTRCEKADTAPGQTLAPRGGSPRSQA-------SRPRINSALHVE 749
                        S   T    +  AP  T +P   +            S P     +H  
Sbjct: 1176 THFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 1235

Query: 750  DKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEV 809
            + + +  R S  S T  S  T     PP     T  A  + P S          +S   +
Sbjct: 1236 ESSTASGR-SEESRTSHSSTTHTISSPP----STTSALVEEPTSYH--------SSPGSI 1282

Query: 810  SSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPASRDA 861
            ++T       H P     S      +T+SHS       + +PA FT + R A
Sbjct: 1283 ATT-------HFPESSTTSGRSE-ESTASHSSPDTNGITPLPAHFTTSGRIA 1326



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 151/661 (22%), Positives = 241/661 (36%), Gaps = 131/661 (19%)

Query: 267 VSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRS 326
           +S  A  +G +++    + SS D    T++   +    T +  + F+  S+  G     S
Sbjct: 38  LSEQARAAGAREKERQEVSSSPDVSELTATKHEE----TVINHSTFSGFSQITGSTVNTS 93

Query: 327 APAAAAAAPPPSTLNPTS-----GSLLNAVDGGPS--HFLASATAAARAQRSEVRYN--- 376
                 +A  PS+ +P +     G  +  + G  +  HFL S+T +  ++ S V ++   
Sbjct: 94  IGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPG 153

Query: 377 --------QRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRG---PASSHCQLAHSSSK 425
                     S  S      K +  +S+   T  LP      G    +++      S  +
Sbjct: 154 ATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 213

Query: 426 TVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCR 485
           T+S    +  SSG +     + + PG T       P S  + P ++     ++   S   
Sbjct: 214 TLSP--ARTTSSGVSEKSTTSHSRPGPTHTI--AFPDS-TTMPGVS-----QESTASHSI 263

Query: 486 PSRPSHTLS-SLATGASRGPPVS---KAPTMDAQQDRPKSQDCLGLL---APLASAAELP 538
           P     TLS    T +S GP  +    +P        P +    GLL    P+ S+   P
Sbjct: 264 PGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSP 323

Query: 539 ST--APVSGKKHRPPGPLF----SSSDPLPA------------TSSHSRDSAQVTSMIPA 580
            T  +P S   H      F    SS D  PA            T+ HS  S+  T+    
Sbjct: 324 HTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTH--- 380

Query: 581 PFTAASRDAG-MRRTRPGTSAPAAAAAAPPPSTLNPTSGSL--LNAVDEGPS-----HFL 632
            F+A+S   G    + P  S+P A A  PPP+  + TSG +    A    P      HF 
Sbjct: 381 -FSASSTTLGHSEESTPVHSSPVATATTPPPAR-SATSGHVEESTAYHRSPGSTQTMHFP 438

Query: 633 ASATAAARARRSQVRYNQRSQT-SRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQ 691
            S+T +  +  S   +   + T S T S     A +S HSS                   
Sbjct: 439 ESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSS------------------- 479

Query: 692 LALSSSNTVSEDGPQAVSSRDTRCEKADTAP---GQTLAPRGGSPRSQASRPRINSALHV 748
             L S+ T        +S R    + + ++P     T+ P G +P               
Sbjct: 480 --LGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP--------------- 522

Query: 749 EDKAISDCRPSR-PSHTLSSLAT-GASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASA 806
               + D  PS   S ++ + A  G++  P +S+  T       P+S D   L A + S 
Sbjct: 523 -SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKST--TFYSSPRSPDTTHLPASMTS- 578

Query: 807 AEVSSTAPVSGKKHRPPGPL----FSSSDPLP-----ATSSHSGDSAQDTSLIPAPFTPA 857
              S  +  S   H  PG      F  S  +P     +T+SHS     DT+L P   T +
Sbjct: 579 ---SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS 635

Query: 858 S 858
           S
Sbjct: 636 S 636



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 146/645 (22%), Positives = 226/645 (35%), Gaps = 84/645 (13%)

Query: 251  SQDCLG-LVAPLASAAEV----SSTAPVSGKKQRP---PGPLFSSSDPLPATSSHSRDSA 302
            SQD  G +V P  S   V    S+T+P+S         PG   +      +T+ HS   +
Sbjct: 837  SQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRS 896

Query: 303  QVTSMIPAPFTAASRDAGMRRTRSAPAAA-AAAPPPSTLNPTSGSLLNAVDGGPSHFLAS 361
              T++ PA  T++        + S P +    A P ST  P            P    ++
Sbjct: 897  PATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG---ST 953

Query: 362  ATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAH 421
             T    A  +     + +    +    +  A   S ++T GL E       +        
Sbjct: 954  DTTLLPASTTTXLVGEPTTSPISSGSTETTALPGS-TTTAGLSEKSTTFYSSPRSPDTTL 1012

Query: 422  SSSKTVSEDGPQAVSSGHTRCEKRADTA-PGQTLAPRGGSPRSQASRPHINSALHVEDKA 480
            S + T S    +  ++ H+R      TA PG T  P G S  S AS     S        
Sbjct: 1013 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQESTASHSSPGS-------- 1063

Query: 481  ISDCRPSRPSHTLSSL---ATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAEL 537
             +D   S  S T SSL   +T    GP  ++   +    D   +   L    P+ S+   
Sbjct: 1064 -TDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLP---DNTTASGLLEASTPVHSSTGS 1119

Query: 538  PST--APVSGKKHRPPGPLF----SSSDPLPA------------TSSHSRDSAQVTSMIP 579
            P T  +P      +     F    SS D +PA            T+SH   S+  T+   
Sbjct: 1120 PRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFS 1179

Query: 580  APFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAA 639
            A  T   R      +    S+P A A  P P+  + TSG     V+E  ++  +  +   
Sbjct: 1180 ASSTTFGRS---EESTTVHSSPVAPATTPSPAR-STTSG----LVEESTAYHSSPGSTQT 1231

Query: 640  RARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNT 699
                     + RS+ SRT      +  SS  S+T  L E      P S H     SS  +
Sbjct: 1232 MHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE-----EPTSYH-----SSPGS 1281

Query: 700  VSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPS 759
            ++       S+   R E++ TA   +    G +P          ++  + +       P 
Sbjct: 1282 IATTHFPESSTTSGRSEES-TASHSSPDTNGITPLP----AHFTTSGRIAESTTFYISPG 1336

Query: 760  RPSHTLSSLAT--GASGGPPV----SKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTA 813
                TL+S AT  G S    +    S++P          S    G    L S AE + T 
Sbjct: 1337 SMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTT 1396

Query: 814  PVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPAS 858
                     P    +S     +T+ HS   + +T+L P   T +S
Sbjct: 1397 AF-------PASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSS 1434



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 84/361 (23%), Positives = 133/361 (36%), Gaps = 49/361 (13%)

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
            S K   P  P  +S+    +T+SH   S+  T+   A  T   R        S+P A A 
Sbjct: 1144 SSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPAT 1203

Query: 334  APPPSTLNPTSGSL--LNAVDGGPS-----HFLASATAAARAQRSEVRYNQR----SQIS 382
             P P+  + TSG +    A    P      HF  S+TA+ R++ S   ++      S   
Sbjct: 1204 TPSPAR-STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP 1262

Query: 383  RTRSCLKRNASSSSHS----STEGLPELKRRRGPASSHCQLAHSSSKT--VSEDGPQAVS 436
             T S L    +S   S    +T   PE     G  S     +HSS  T  ++       +
Sbjct: 1263 STTSALVEEPTSYHSSPGSIATTHFPESSTTSG-RSEESTASHSSPDTNGITPLPAHFTT 1321

Query: 437  SGHTRCEKRADTAPGQ---TLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTL 493
            SG          +PG    TLA    +P   A    + S+    D+ +S           
Sbjct: 1322 SGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSP---------- 1371

Query: 494  SSLATGASRGPPVSKAPTMDAQQDR--PKSQDCLGLLAPLASAAELPSTAPVSGKKHRPP 551
            +S+ + +  G P S     ++      P S    G    L+  +    + P S +    P
Sbjct: 1372 ASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG----LSQESTTFHSKPGSTETTLSP 1427

Query: 552  GPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPS 611
            G + +SS     T+ HS+  + ++++ PA  T            PG S  +    + P S
Sbjct: 1428 GSITTSSFAQEFTTPHSQPGSALSTVSPASTTV-----------PGLSEESTTFYSSPGS 1476

Query: 612  T 612
            T
Sbjct: 1477 T 1477



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 155/679 (22%), Positives = 231/679 (34%), Gaps = 128/679 (18%)

Query: 205 HVEDKAISDCRPSR------PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 258
           H E+  +S   P        PSH+ +S+  G     P++ A +M+     P S    GL 
Sbjct: 141 HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA-SMETTA-LPGSTTTAGL- 197

Query: 259 APLASAAEVSST---APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAA 315
                 +E S+T   +P S  +   P    SS     +T+SHSR     T   P   T  
Sbjct: 198 ------SEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMP 251

Query: 316 SRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRY 375
                   + S P +      P T  P+S              L   +    +     + 
Sbjct: 252 GVSQESTASHSIPGSTDTTLSPGTTTPSS--------------LGPESTTFHSSPGYTKT 297

Query: 376 NQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAV 435
            +    + T   L+  AS+  HSST             S H  L+ +SS T  E  P   
Sbjct: 298 TRLPDNTTTSGLLE--ASTPVHSST------------GSPHTTLSPASS-TTHEGEPTTF 342

Query: 436 SSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSS 495
            S         DT+P    AP G    + ++   +++  H    +      S  S TL  
Sbjct: 343 QS----WPSSKDTSP----APSG----TTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGH 390

Query: 496 LATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLF 555
               +    PV  +P   A    P      G +          STA      HR PG   
Sbjct: 391 ----SEESTPVHSSPVATATTPPPARSATSGHVE--------ESTA-----YHRSPGSTQ 433

Query: 556 SSSDPLPATSS-HSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLN 614
           +   P  +T+S HS +SA          T        + + P T+  AA A     S+L 
Sbjct: 434 TMHFPESSTTSGHSEESA----------TFHGSTTHTKSSTPSTT--AALAHTSYHSSLG 481

Query: 615 PTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRS-------QTSRTRSCLKRNASS 667
            T            +HF  S+T + R+  S+  ++              T S L  +++ 
Sbjct: 482 STE----------TTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTP 531

Query: 668 SSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPG---- 723
           S  SS  G  E     G   S  +  LS  +T     P+  S   T    + T+ G    
Sbjct: 532 SPISS--GSMETTALPG---STTKPGLSEKSTTFYSSPR--SPDTTHLPASMTSSGVSEE 584

Query: 724 -QTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP 782
             T   R GS  + A           ++   S   P     TLS  +T AS     S  P
Sbjct: 585 STTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS-----SLGP 639

Query: 783 TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPP---GPLFSSSDPLPATSSH 839
                  RP S +   L     ++  + ++ PV      P     P  S++    +T+ H
Sbjct: 640 EYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFH 699

Query: 840 SGDSAQDTSLIPAPFTPAS 858
           S  S+ DT   PAP T  S
Sbjct: 700 SWPSSNDTR--PAPPTTTS 716


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 184/751 (24%), Positives = 251/751 (33%), Gaps = 128/751 (17%)

Query: 143 APRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINS 202
           A  G + R+ A+R      P  P   G P   PP      RV      + ++   +R   
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPP---GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 203 ALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLA 262
              +    I +  P R   T S+   G S   P S+ P     +  P +++         
Sbjct: 65  ---IGGATIPESAP-RAGPTRSA---GTSSRNPASRPPASGRGERAPPAKN--------T 109

Query: 263 SAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMR 322
           S   VSS    SG  +  PGPL      + A  + +R  A       AP  +A   AG R
Sbjct: 110 SPGPVSSPGRASGTTR--PGPLGQKGLRISAEETVARGKAT-----EAPKRSAL-SAGAR 161

Query: 323 RTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAAR---AQRSEVRYNQRS 379
           R  S P     +P  +  +  +G+ +      PS      T   R   +  SE    + S
Sbjct: 162 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221

Query: 380 QISRTRSC----LKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAV 435
             +R R      L+R AS S  SS   L     R GP++     A +        G QA+
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSARGTPRAPAHPSQPKPKGLQAL 280

Query: 436 SSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVE--DKAISDCRPSRPSHTL 493
                    R D AP   L P   SP +  S P    A  V   D A +    + P    
Sbjct: 281 RPPQVT-PPRKDAAPA--LGPLSSSPLATPS-PSGTKARPVPPPDNAATPLPATLPPSP- 335

Query: 494 SSLATGASRGPPVSKAP----TMDAQQDRPKSQDCLGLLAPLASAAELPSTAP------- 542
             LAT     PP   AP    T+ +    P SQ    +  P   A     T P       
Sbjct: 336 -PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394

Query: 543 -VSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVT----SMIP----APFTAASRDAGMRR 593
             S     PP PL  SS  L AT+S    + Q T    +M P    A  T+ SR A    
Sbjct: 395 LTSPSLQAPPSPLALSS--LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452

Query: 594 TRPGTSAPAAAAAAPPPST-LNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRS 652
             P   AP +  A+PP  T L+P    L + +   P   L+S                  
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL----------------- 495

Query: 653 QTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRD 712
                          +SHS           + P SS     L + +++      A  S  
Sbjct: 496 ---------------ASHSP----------QAPLSSLIMPPLETQSSL------APPSLQ 524

Query: 713 TRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVED-------KAISDCRPSRPSHTL 765
           T      T P + L      P   AS P     L           +A      + P  T 
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584

Query: 766 SSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGP 825
           SS+AT     PP   +P +      P S     L  P   A    +  P+      P  P
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSP----LATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 826 LFSSSDPLPATSSHSGDSAQDTSLIPAPFTP 856
             S   PL AT S    +A    L+ APF+P
Sbjct: 641 PLS---PL-ATPSPQAPNALAVHLLQAPFSP 667



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 201/859 (23%), Positives = 292/859 (33%), Gaps = 101/859 (11%)

Query: 35  RDNGGLSPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTK--RNAISSSYSSTGGLP 92
           RD  G +P  P P   +    A  +E+   + + ++     T+  R ++SS+   +   P
Sbjct: 162 RDTSGPTPGTPSPAMARRS-RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220

Query: 93  GLKQRRGPASS---RCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRG--G 147
               RR P++    +   + S S + +     A S    R    A   P Q   P+G   
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQA 279

Query: 148 SPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYR-VTAEDLHLEKQAAFQRINSALHV 206
               Q + PR+   P L      PL  P P     R V   D            N+A  +
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD------------NAATPL 327

Query: 207 EDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAE 266
                +   PS P  T   LA  +   PP     T+ +    P SQ    +  P   A  
Sbjct: 328 P----ATLPPSPPLATPLPLAPPSPSAPP--SLQTLPSPPATPPSQAPPSMTTPPMQAPP 381

Query: 267 VSSTAP--------VSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVT----SMIP----A 310
              T P         S   Q PP PL  SS  L AT+S    + Q T    +M P    A
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSS--LQATTSLGSPTLQATHSFLTMSPRQTQA 439

Query: 311 PFTAASRDAGMRRTR---SAPAAAAAAPPPST-LNPTSGSLLNAVDGGPSHFLAS-ATAA 365
             T+ SR A          AP +  A+PP  T L+P    L + +   P   L+S A+ +
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499

Query: 366 ARAQRSE-VRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSS 424
            +A  S  +     +Q S     L+   +S +    E LP L      A    Q A +  
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL------APPPLQTASAPL 553

Query: 425 KTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDC 484
            T   + P   +     C  +A  +P  T  P   +P S A+ P             S  
Sbjct: 554 TTPHLETPPCPAP----CPLQAPPSPLTTPPPE--TPSSIATPPP-----QAPPALASPP 602

Query: 485 RPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVS 544
               PS  LS LAT   + PP    P + A    P S     L  P   A    +   + 
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662

Query: 545 GKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAA 604
                PP P   +    PA+   S  SA   S  P    A           P  S P + 
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQV---PPSPPASPPMSP 718

Query: 605 AAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARAR------RSQVRYNQRSQTSRTR 658
           +A PPP    P +   L      P+    S +A    R         ++       S   
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778

Query: 659 SCLKRNASSSSHS-STEGLQELKR------RRGPASSHCQLALSSSNTVSEDGPQAVSSR 711
           S L +    +  + +T  LQ L         + P S    L +S   T     P  +++ 
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 838

Query: 712 DTRCEKADTAPGQTLAPR---GGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSL 768
             +   +  A     APR      P +  S PR+  AL       +   P  PS + SS 
Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-------APGPPPPPSRSPSST 891

Query: 769 ATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFS 828
            +G       S A +   +     S    G  A     AE+++  P +  +   P   F 
Sbjct: 892 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 951

Query: 829 SSD--PL---PATSSHSGD 842
            +   PL   PAT   S D
Sbjct: 952 GAPGAPLPWPPATGPGSAD 970



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 164/747 (21%), Positives = 248/747 (33%), Gaps = 89/747 (11%)

Query: 101 ASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRK 160
           A  R  L+    +  S   P   S    R  +AA T  G         PR     PR+  
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS- 208

Query: 161 IPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPS 220
              + S        P P     R  +    L++ A+    +SA  +   A      S PS
Sbjct: 209 ---VSSASEHSTTEPSP--AARRRPSAGGGLQRPASRSLSSSATPLSSPA-----RSGPS 258

Query: 221 HTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRP 280
              +  A      P       +   Q  P  +D    + PL+S+    +T   SG K RP
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP--LATPSPSGTKARP 316

Query: 281 PGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTL 340
             P  +++ PLPAT      S  + + +P    + S    ++   S PA   +  PPS  
Sbjct: 317 VPPPDNAATPLPATLP---PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT 373

Query: 341 NP---TSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSH 397
            P      SL         H L S +  A      +                   SS   
Sbjct: 374 TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL-------------------SSLQA 414

Query: 398 SSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPR 457
           +++ G P L+      ++H  L  S         P+   +  T   + A T P    +P 
Sbjct: 415 TTSLGSPTLQ------ATHSFLTMS---------PRQTQASLTSPSRPASTPPD---SPP 456

Query: 458 GGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSK-APTMDAQQ 516
             +P S  + P + ++L      +S      P   LSSLA+ + + P  S   P ++ Q 
Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516

Query: 517 D-RPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPL--PATSSHSRDSAQ 573
              P S     L  P AS     +T P+       P PL ++S PL  P   +    +  
Sbjct: 517 SLAPPS-----LQTPPASL----TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC 567

Query: 574 VTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHF-L 632
                P+P T    +       P   AP A A+ P     +P    L     + P    L
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627

Query: 633 ASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQL 692
               A      S       + + +  + L  +   +  S           + P S     
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS----PPVQAPFSPPASP 683

Query: 693 ALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKA 752
            +S S T     P ++++   +   +  A    ++P   +P  QA  P     L V    
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSP-SATPPPQAPPPLAAPPLQVP--- 738

Query: 753 ISDCRPSRP-SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSS 811
                PS P S  +S  AT     PP+  AP +      P S     L  P   A    +
Sbjct: 739 -----PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793

Query: 812 TAPVSGKKHRP---PGPL-FSSSDPLP 834
           T P+      P   PG   FS S  LP
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLP 820


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 135/560 (24%), Positives = 203/560 (36%), Gaps = 58/560 (10%)

Query: 310 APFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQ 369
           AP T     A   RT   P+ A+    PS  + T      ++ G PS    + T   RA 
Sbjct: 2   APPTRTPSRASPTRT---PSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPP-RAS 57

Query: 370 RSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSE 429
                      +S +R+ L R  SSS  + T  +  LKR    AS    L  +S      
Sbjct: 58  LKGTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMR--- 114

Query: 430 DGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRP 489
              +  ++  TR   RA      T  P   S  S +  P   +AL +  +A     P R 
Sbjct: 115 ---RPSTASLTRSPSRASL----TTTP---SRASLSMTPSTAAALTMPSRASLTRTPPRA 164

Query: 490 SHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHR 549
           S T++      +R PP   +PT    +  P        L  + S A +  T   +     
Sbjct: 165 SLTMTPSTASLTRTPP-RASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGT 223

Query: 550 PP------GPLFSSSDPLPATSSHSR--DSAQVTSMIP-APFTAASRDAGMRRT--RPGT 598
           PP       P  +S   +P+T+   R    A  T M+     T     A + RT  RP T
Sbjct: 224 PPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPST 283

Query: 599 SAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAAR--ARRSQVRYNQRSQTSR 656
           ++P    +    S + P++ SL+  +       + S T+  +  +  S  R   R+  +R
Sbjct: 284 ASPTGTPSRASLS-MTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITR 342

Query: 657 TRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSS-SNTVSEDG-PQAVSSRDTR 714
           T S     AS +   ST        R  P  S    +L+  S+T S  G P   S   T 
Sbjct: 343 TPS----RASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTP 398

Query: 715 CEKADTAPGQTLAPRG----------GSPRSQASRPRINSALHVEDKAISDCRPSRPSHT 764
              + T      +P G           S  S    P   S      +A     PSR S T
Sbjct: 399 STASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPT 458

Query: 765 LSSLATGASGGPPVSKAPTMDAQQDRP---KSQDCLGLVAPLASAAEVSSTAPVSGKKHR 821
             + +T +  G P + +PT       P    S+  L      AS  ++ STA ++    R
Sbjct: 459 -GTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSR 517

Query: 822 PPGPLFSSSDPLPATSSHSG 841
                 +S    P+T+S +G
Sbjct: 518 ------ASPTWTPSTASPTG 531



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 143/601 (23%), Positives = 211/601 (35%), Gaps = 80/601 (13%)

Query: 248 RPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPP-GPLFSSSDPLPATSSHSRDSAQVTS 306
           R  S   L  + P AS      T P +   +RP    L  S      T++ SR S  +T 
Sbjct: 87  RTPSMASLKRMPPRASRTR---TLPRASLMRRPSTASLTRSPSRASLTTTPSRASLSMTP 143

Query: 307 MIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAA 366
              A  T  SR A + RT   P  A+    PST + T      +  G PS    ++    
Sbjct: 144 STAAALTMPSR-ASLTRT---PPRASLTMTPSTASLTRTPPRASPTGMPSR---TSPTGM 196

Query: 367 RAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPE----------LKRRRGPASSH 416
            +  S  + +  + I+RT S      +    S T   P           L  R  P +S 
Sbjct: 197 PSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASP 256

Query: 417 CQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASR-PHINSALH 475
             +   +S T  +      ++  TR   R  TA     +P G   R+  S  P   S + 
Sbjct: 257 TGMLSRTSLTKMDS-----TASITRTPSRPSTA-----SPTGTPSRASLSMTPSTASLMR 306

Query: 476 VEDKAISDCRPSRPSHTLSSLATGASRGPP---VSKAPTMDAQQDRPKSQDCLGLLAPLA 532
           +  +A      SR S T        SR PP   +++ P+  +   +P +    G  +  A
Sbjct: 307 MLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSR-A 365

Query: 533 SAAELPSTAPVSGKKHR--PPG-PLFSSSDPLPATSSHSRDS--AQVTSMIP-APFTAAS 586
           S    PSTA ++G      P G P  +S    P+T+S +R    A  T M+     T   
Sbjct: 366 SPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMD 425

Query: 587 RDAGMRRTRPG---TSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARR 643
             A   RT P    T  P  A+    PS  +PT      +    PS   AS T +     
Sbjct: 426 STASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPS--TASPTGSP---- 479

Query: 644 SQVRYNQRSQT-SRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSE 702
                +  S T S +R+ L R  S +S +  E    + R                     
Sbjct: 480 -----STASPTGSPSRASLTRTPSRASLTKMESTASITRT-------------------- 514

Query: 703 DGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPS 762
             P   S   T    + T    T    G   R+  +R    ++L       S   PSR S
Sbjct: 515 --PSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRAS 572

Query: 763 HTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRP 822
            T +      +  PP S +PT    +  P       L+  + S A ++ T P +     P
Sbjct: 573 LTRTPSTVLLTRMPP-SASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETP 631

Query: 823 P 823
           P
Sbjct: 632 P 632



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 153/693 (22%), Positives = 231/693 (33%), Gaps = 125/693 (18%)

Query: 56  AQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTV 115
           +++S  R   +S  + T S      +    S T  LP     R P+++   LT S S+  
Sbjct: 72  SRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTA--SLTRSPSRAS 129

Query: 116 SEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMP 175
               P   S   T    AA T P         S  S    P R  + + PS     L   
Sbjct: 130 LTTTPSRASLSMTPSTAAALTMP---------SRASLTRTPPRASLTMTPSTAS--LTRT 178

Query: 176 PPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP 235
           PP                               +A     PSR S T         G P 
Sbjct: 179 PP-------------------------------RASPTGMPSRTSPT---------GMPS 198

Query: 236 VSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATS 295
            +    MD+             +    S A  + T P +     PP    S   P  A  
Sbjct: 199 TASLTKMDSTAS----------ITRTLSRASPTGTPPRASPTGSPPRASLSMM-PSTALL 247

Query: 296 SHSRDSAQVTSMIP-APFTAASRDAGMRRTRSAPAAAAAAPPPS----TLNPTSGSLLNA 350
             +   A  T M+     T     A + RT S P+ A+    PS    ++ P++ SL+  
Sbjct: 248 IRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRM 307

Query: 351 VDGGPSHFLASATAAAR--AQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKR 408
           +       + S T+  +  +  S  R   R+ I+RT S        S+ S T G P    
Sbjct: 308 LPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPT-GTPSRAS 366

Query: 409 RRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRP 468
             G  S+      SS+ + +   P+A  +G         +    T  P   SP    SR 
Sbjct: 367 PTGSPSTASLTGLSSTASPTGTPPRASPTG-------TPSTASLTRKPPRASPTGMLSRT 419

Query: 469 HINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLL 528
            I     ++  A     P R S T          G P   +PT    +  P         
Sbjct: 420 SITK---MDSTASPTRTPPRASPT----------GTPPRASPTGTPSRASPTGTQ----- 461

Query: 529 APLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRD 588
              AS    PSTA  +G     P     +  P  A+ + +   A +T             
Sbjct: 462 -STASPTGSPSTASPTGS----PSTASPTGSPSRASLTRTPSRASLTK------------ 504

Query: 589 AGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRY 648
             M  T   T  P+ A+    PST +PT GS   A+  G     A     +RA  ++   
Sbjct: 505 --MESTASITRTPSRASPTWTPSTASPT-GSPSTALAMGSPSRAALTRTPSRASLTRTP- 560

Query: 649 NQRSQTSRTRSCLKRNASS------SSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSE 702
           ++ S T+ +R+ L R  S+         +S  G+       G  SS     + S+ +++ 
Sbjct: 561 SRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITR 620

Query: 703 DGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRS 735
             P+A S  +T    + T      +P G  PR+
Sbjct: 621 TPPRA-SPTETPPRASPTGTPPRASPTGTPPRA 652


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 135/592 (22%), Positives = 209/592 (35%), Gaps = 79/592 (13%)

Query: 293 ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSL--LNA 350
           +T+ HS  S+  T+   A  T            S+P A A  PPP+  + TSG +    A
Sbjct: 301 STTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR-SATSGHVEESTA 359

Query: 351 VDGGPS-----HFLASATAAARAQRSEVRYNQRSQI-SRTRSCLKRNASSSSHSSTEGLP 404
               P      HF  S+T +  ++ S   +   +   S T S     A +S HSS  G  
Sbjct: 360 YHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL-GST 418

Query: 405 ELKRRRGPASSHCQLAHSSSKTVSED--GPQAVSSGHTRCEKRADTAPGQTLAPRGGSPR 462
           E    R  ++   +   S +   S D      + +G T      D+ P    +P      
Sbjct: 419 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTP----SPISSGSM 474

Query: 463 SQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQ 522
              + P   +   + +K+ +     R   T    A   S G  VS+  T      RP S 
Sbjct: 475 ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPARMTSSG--VSEEST--TSHSRPGST 530

Query: 523 DCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSS---------HSRDSAQ 573
                      +  +P  +  S   H  PGP  ++  P   T+S         HS   + 
Sbjct: 531 H----TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPGST 586

Query: 574 VTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLA 633
            T+++P   TA    +G+       S P  ++   P +TL+P +GS     +    H   
Sbjct: 587 ETTLLPDNTTA----SGLLE----ASTPVHSSTRSPHTTLSP-AGSTTRQGESTTFHSWP 637

Query: 634 SATAAARARRSQV-RYNQRSQTSRTRSCLKRNASSSSHSSTEGL-QELKRRRGPASSHCQ 691
           S+     A  +    + + S TS            S+ S+T GL +E         S   
Sbjct: 638 SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 697

Query: 692 LALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDK 751
           +    S+T S  G ++ +S  +      +AP  T A     P S  S P   +  H  D 
Sbjct: 698 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA-LVEEPTSYHSSPGSTATTHFPD- 755

Query: 752 AISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLG-LVAPLASAAEV- 809
                         SS  +G S     S +           SQD  G +V P  S   V 
Sbjct: 756 --------------SSTTSGRSEESTASHS-----------SQDATGTIVLPARSTNSVL 790

Query: 810 ---SSTAPVSGKKHRP---PGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFT 855
              S+T+P+S         PG   +      +T+ HS   +  T+L PA  T
Sbjct: 791 LGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 842



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 139/601 (23%), Positives = 207/601 (34%), Gaps = 144/601 (23%)

Query: 293 ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVD 352
           +T SHS   A  T++ P                S  A +     P T   TS S+     
Sbjct: 80  STVSHSGPGATGTTLFP----------------SHSATSVFVGEPKTSPITSASMETTAL 123

Query: 353 GGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGP 412
            G      S T A  +++S   Y+      RT S  +  +S  S  ST        R GP
Sbjct: 124 PG------STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTS----HSRPGP 173

Query: 413 ASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQA--SRPHI 470
             +   +A   S T+     ++ +S           +PG T  P    P S    S P  
Sbjct: 174 THT---IAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTT-TPSSLGPESTTFHSSPGY 229

Query: 471 NSALHVEDKAISD--CRPSRPSH--------TLSSLATGASRGPPVSKAPTMDAQQDRPK 520
                + D   +      S P H        TLS  ++    G P +        Q  P 
Sbjct: 230 TKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTF-------QSWPS 282

Query: 521 SQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPA 580
           S+D                T+P       P G   +S+    +T+ HS  S+  T+    
Sbjct: 283 SKD----------------TSPA------PSGT--TSAFVKLSTTYHSSPSSTPTTH--- 315

Query: 581 PFTAASRDAG-MRRTRPGTSAPAAAAAAPPPSTLNPTSGSL--LNAVDEGPS-----HFL 632
            F+A+S   G    + P  S+P A A  PPP+  + TSG +    A    P      HF 
Sbjct: 316 -FSASSTTLGHSEESTPVHSSPVATATTPPPAR-SATSGHVEESTAYHRSPGSTQTMHFP 373

Query: 633 ASATAAARARRSQVRYNQRSQT-SRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQ 691
            S+T +  +  S   +   + T S T S     A +S HSS                   
Sbjct: 374 ESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSS------------------- 414

Query: 692 LALSSSNTVSEDGPQAVSSRDTRCEKADTAP---GQTLAPRGGSPRSQASRPRINSALHV 748
             L S+ T        +S R    + + ++P     T+ P G +P               
Sbjct: 415 --LGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP--------------- 457

Query: 749 EDKAISDCRPSR-PSHTLSSLAT-GASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASA 806
               + D  PS   S ++ + A  G++  P +S+  T       P+S D   L A + S 
Sbjct: 458 -SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKST--TFYSSPRSPDTTHLPARMTS- 513

Query: 807 AEVSSTAPVSGKKHRPPGPL----FSSSDPLP-----ATSSHSGDSAQDTSLIPAPFTPA 857
              S  +  S   H  PG      F  S  +P     +T+SHS     DT+L P   T +
Sbjct: 514 ---SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS 570

Query: 858 S 858
           S
Sbjct: 571 S 571



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 130/686 (18%), Positives = 223/686 (32%), Gaps = 88/686 (12%)

Query: 216 PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTA---P 272
           P  P  TLS   T +SG   VS+  T    +  P           +   ++ S+ +   P
Sbjct: 143 PRSPDRTLSPARTTSSG---VSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIP 199

Query: 273 VSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAA 332
            S      PG    SS    +T+ HS      T+ +P   T +    G+    S P  ++
Sbjct: 200 GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTS----GLLEA-STPVHSS 254

Query: 333 AAPPPSTLNPTSGSLLNAVDGGPSHFLA-----------SATAAARAQRSEVRYNQRSQI 381
              P +TL+P+S +     +G P+ F +           S T +A  + S   ++  S  
Sbjct: 255 TGSPHTTLSPSSST---THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSST 311

Query: 382 SRTRSCLKRNASSSSHSST--EGLPELKRRRGPASSHCQLAHSSSKTVSEDGP------- 432
             T           S  ST     P       P +      H    T     P       
Sbjct: 312 PTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMH 371

Query: 433 ---QAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHIN--------SALHVEDKAI 481
               + +SGH+   + + T  G T   +  +P + A+  H +           H  D + 
Sbjct: 372 FPESSTTSGHS---EESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSST 428

Query: 482 SDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPK-----SQDCLGLLAP-----L 531
              R      + SS    A+   P    P++      P      S +   L        L
Sbjct: 429 ISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGL 488

Query: 532 ASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFT--AASRDA 589
           +  +    ++P S      P  + SS     +T+SHSR  +  T+  P   T    S+++
Sbjct: 489 SEKSTTFYSSPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQES 548

Query: 590 GMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYN 649
               + PG +    +  +   S+L P   +  ++     +  L   T A+    +    +
Sbjct: 549 TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 608

Query: 650 QRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVS 709
             +++  T      + +    S+T       +   PA      A    +T S   P ++ 
Sbjct: 609 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 668

Query: 710 SRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLA 769
           +  T      T  G           +  S P     +H  +   +  R    + + SS  
Sbjct: 669 T--THISARSTTSGLV-----EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTT 721

Query: 770 TGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSS 829
              S  P  + A   +                P +  +   STA      H P     S 
Sbjct: 722 HTISSAPSTTSALVEE----------------PTSYHSSPGSTATT----HFPDSSTTSG 761

Query: 830 SDPLPATSSHSGDSAQDTSLIPAPFT 855
                +T+SHS   A  T ++PA  T
Sbjct: 762 RSE-ESTASHSSQDATGTIVLPARST 786



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 81/398 (20%), Positives = 140/398 (35%), Gaps = 30/398 (7%)

Query: 475 HVEDKAISDCRPSR------PSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLL 528
           H E+  +S   P        PSH+ +S+  G  +  P++ A +M+     P S    GL 
Sbjct: 76  HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA-SMETTA-LPGSTTTAGL- 132

Query: 529 APLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFT--AAS 586
              +  +    ++P S  +   P    SS     +T+SHSR     T   P   T    S
Sbjct: 133 ---SEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 189

Query: 587 RDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQV 646
           +++    + PG++    +     PS+L P S +  ++     +  L   T  +    +  
Sbjct: 190 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 249

Query: 647 RYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQ 706
             +  + +  T      + +     +T       +   PA S    A    +T     P 
Sbjct: 250 PVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPS 309

Query: 707 AVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRP---RINSALHVEDKAISDCRPSRPSH 763
           +  +             +   P   SP + A+ P   R  ++ HVE+       P   + 
Sbjct: 310 STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGS-TQ 368

Query: 764 TL----SSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK 819
           T+    SS  +G S         T   +   P +       A LA  +  SS        
Sbjct: 369 TMHFPESSTTSGHSEESATFHGSTTHTKSSTPST------TAALAHTSYHSSLGSTETTH 422

Query: 820 HRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPA 857
            R    +   S+   A  SHS   A  T+++PA  TP+
Sbjct: 423 FRDSSTISGRSEESKA--SHSSPDAMATTVLPAGSTPS 458



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 145/678 (21%), Positives = 224/678 (33%), Gaps = 103/678 (15%)

Query: 205 HVEDKAISDCRPSR------PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 258
           H E+  +S   P        PSH+ +S+  G     P++ A +M+     P S    GL 
Sbjct: 76  HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA-SMETTA-LPGSTTTAGL- 132

Query: 259 APLASAAEVSST---APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAA 315
                 +E S+T   +P S  +   P    SS     +T+SHSR     T   P   T  
Sbjct: 133 ------SEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMP 186

Query: 316 SRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRY 375
                   + S P +      P T  P+S              L   +    +     + 
Sbjct: 187 GVSQESTASHSIPGSTDTTLSPGTTTPSS--------------LGPESTTFHSSPGYTKT 232

Query: 376 NQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAV 435
            +    + T   L+  AS+  HSST             S H  L+ SSS T  E  P   
Sbjct: 233 TRLPDNTTTSGLLE--ASTPVHSST------------GSPHTTLSPSSS-TTHEGEPTTF 277

Query: 436 SSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALH--VEDKAISDCRPSRPSHTL 493
            S  +   K    AP  T +       +  S P      H       +     S P H+ 
Sbjct: 278 QSWPS--SKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHS- 334

Query: 494 SSLATGASRGPPVSKAPTMDAQQDR-----PKSQDCLGLLAPLASAAELPSTAPVSGKKH 548
           S +AT A+  PP   A +   ++       P S   +       ++     +A   G   
Sbjct: 335 SPVAT-ATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTT 393

Query: 549 RPPGPLFSSSDPLPATSSHS----------RDSAQVTSMIP-APFTAASRDAGMRRTRPG 597
                  S++  L  TS HS          RDS+ ++     +  + +S DA      P 
Sbjct: 394 HTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPA 453

Query: 598 TSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRT 657
            S P+       PS ++  SGS+      G      S T    + +S   Y+       T
Sbjct: 454 GSTPSVLVGDSTPSPIS--SGSMETTALPG------STTKPGLSEKSTTFYSSPRSPDTT 505

Query: 658 RSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEK 717
               +  +S  S  ST           P S+H   A   S T+       +S   T    
Sbjct: 506 HLPARMTSSGVSEESTTSHSR------PGSTHTT-AFPGSTTMP-----GLSQESTASHS 553

Query: 718 ADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP 777
           +      TL+P  GS  + +  P   +  H           S P  T ++L    +    
Sbjct: 554 SPGPTDTTLSP--GSTTASSLGPEYTT-FH-----------SSPGSTETTLLPDNTTASG 599

Query: 778 VSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATS 837
           + +A T      R          +        +  +  S K  RP  P  +S+   P+T+
Sbjct: 600 LLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTT 659

Query: 838 SHSGDSAQDTSLIPAPFT 855
           SH   S+  T+ I A  T
Sbjct: 660 SHGSPSSIPTTHISARST 677



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 44/191 (23%), Positives = 69/191 (36%), Gaps = 7/191 (3%)

Query: 274 SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
           S K  RP  P  +S+   P+T+SH   S+  T+ I A  T +          S+P +   
Sbjct: 638 SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 697

Query: 334 AP-PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNA 392
              P S      G          +H ++SA +   A   E   +  S    T +    ++
Sbjct: 698 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGSTATTHFPDS 756

Query: 393 SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQ 452
           S++S  S E       +    +       ++S  + E     +SSG           PG 
Sbjct: 757 STTSGRSEESTASHSSQDATGTIVLPARSTNSVLLGESTTSPISSG----SMETTALPGS 812

Query: 453 TLAPRGGSPRS 463
           T  P G S RS
Sbjct: 813 TTTP-GLSERS 822



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 32/142 (22%)

Query: 747 HVEDKAISDCRPSR------PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 800
           H E+  +S   P        PSH+ +S+  G     P++ A +M+     P S    GL 
Sbjct: 76  HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA-SMETTA-LPGSTTTAGLS 133

Query: 801 AP--------------LASAAEVSS-TAPVSGKKHRPPGPL----FSSSDPLP-----AT 836
                           L+ A   SS  +  S   H  PGP     F  S  +P     +T
Sbjct: 134 EKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQEST 193

Query: 837 SSHSGDSAQDTSLIPAPFTPAS 858
           +SHS   + DT+L P   TP+S
Sbjct: 194 ASHSIPGSTDTTLSPGTTTPSS 215


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 132/613 (21%), Positives = 223/613 (36%), Gaps = 46/613 (7%)

Query: 274 SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAA 333
           S K  RP  P  +S+   P+T+SH   S+  T+ I A  T +          S+P +   
Sbjct: 269 SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 328

Query: 334 AP-PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNA 392
              P S      G          +H ++SA +   A   E   +  S    T +    ++
Sbjct: 329 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGSTATTHFPDS 387

Query: 393 SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSG--HTRCEKRADTAP 450
           S++S  S E       +    +       ++S  + E     +SSG   T     + T P
Sbjct: 388 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 447

Query: 451 GQTLAPRG----GSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
           G  L+ R      SPRS A+     S         S    SRP  T ++    ++  P +
Sbjct: 448 G--LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 505

Query: 507 SKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHR-------PPGPLFSSSD 559
           S+  T       P S D    L P ++    PS    +             PG   + S 
Sbjct: 506 SRHST--TSHSSPGSTDT--TLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSF 561

Query: 560 PLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGS 619
              +T+ HS   +  T++ P   T++       R    T +P    +  P S+ +P    
Sbjct: 562 GQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS--PASSTSPGLQG 619

Query: 620 LLNAVDEGP--SHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQ 677
              A    P  +H   S  + A A   +     RS  S   +    ++++S HS    + 
Sbjct: 620 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 679

Query: 678 ELKRRRG---PASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRG--GS 732
                     P+S+H   +    +T S   P   S+  T    + T PG + A      S
Sbjct: 680 HSSPDASGTTPSSAHSTTSGRGESTTSRISPG--STEITTLPGSTTTPGLSEASTTFYSS 737

Query: 733 PRSQAS--RPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDR 790
           PRS  +   P   ++L V ++  S    S+P  T S+++  ++  P +S+  T      R
Sbjct: 738 PRSPTTTLSPASMTSLGVGEE--STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSR 795

Query: 791 PKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLI 850
             ++     V P ++   V    P +        P  + +      S+ SG + + T+  
Sbjct: 796 GSTET---TVFPHSTTTSVHGEEPTTFHSR----PASTHTTLFTEDSTTSGLTEESTAF- 847

Query: 851 PAPFTPASRDAGV 863
             P +PAS   G+
Sbjct: 848 --PGSPASTQTGL 858



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 136/628 (21%), Positives = 222/628 (35%), Gaps = 89/628 (14%)

Query: 261 LASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAG 320
           L+  +  S ++P        PG   +SS     T+ HSR  +  T+++P   TA    +G
Sbjct: 175 LSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTA----SG 230

Query: 321 MRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASA---------TAAARAQRS 371
           +    S P  ++   P +TL+P +GS     +    H   S+         T +A  + S
Sbjct: 231 LLEA-SMPVHSSTRSPHTTLSP-AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS 288

Query: 372 EVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAH-SSSKTVSED 430
              +   S I  T          S+ S+T GL E       +    Q  H   S T S  
Sbjct: 289 TTSHGSPSSIPTTH--------ISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGR 340

Query: 431 GPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCR--PSR 488
           G ++ +S H+       +AP  T A     P S  S P   +  H  D + +  R   S 
Sbjct: 341 GEESTTS-HSSTTHTISSAPSTTSA-LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 398

Query: 489 PSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAA----ELPSTAPVS 544
            SH+ S  ATG    P  S    +  +             +P++S +     LP +    
Sbjct: 399 ASHS-SQDATGTIVLPARSTTSVLLGE----------STTSPISSGSMETTALPGSTTTP 447

Query: 545 GKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAA--SRDAGMRRTRPG---TS 599
           G   R             +T+ HS   +  T++ PA  T++  S ++   R+RPG   T+
Sbjct: 448 GLSER-------------STTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTT 494

Query: 600 APAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRS 659
           A   +   P  S  + TS S   + D   +   AS T +  ++ S   ++    T    S
Sbjct: 495 AFPDSTTTPGLSRHSTTSHSSPGSTD--TTLLPASTTTSGPSQESTTSHSSSGSTDTALS 552

Query: 660 CLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKAD 719
                A S    ST           P S+H  L   S+ +        +    TR   + 
Sbjct: 553 PGSTTALSFGQEST------TFHSNPGSTHTTLFPDSTTS------SGIVEASTRVHSST 600

Query: 720 TAPGQTLAPRGG-SPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGAS----- 773
            +P  TL+P    SP  Q       S       A +   PS PS   + +    +     
Sbjct: 601 GSPRTTLSPASSTSPGLQG-----ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 655

Query: 774 GGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSS--- 830
           G  P +  P         +           +     S+ +  SG+       +   S   
Sbjct: 656 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 715

Query: 831 DPLPATSSHSGDSAQDTSLIPAPFTPAS 858
             LP +++  G S   T+   +P +P +
Sbjct: 716 TTLPGSTTTPGLSEASTTFYSSPRSPTT 743



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 183/879 (20%), Positives = 307/879 (34%), Gaps = 119/879 (13%)

Query: 19   TVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWT--SSST 76
            T P ++ ++ + +   R +   + F   P    T +H +     +++ + T  T  +  +
Sbjct: 779  TTPGLSEESTTVYSSSRGSTETTVF---PHSTTTSVHGEEPTTFHSRPASTHTTLFTEDS 835

Query: 77   KRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADT 136
              + ++   ++  G P   Q   PA+    LT +     S   P +  S  T+   A  T
Sbjct: 836  TTSGLTEESTAFPGSPASTQTGLPAT----LTTADLGEESTTFPSSSGSTGTKLSPARST 891

Query: 137  APGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAA 196
              G      G S  S+ S P   +   LP     P +            + D  L     
Sbjct: 892  TSGLV----GESTPSRLS-PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 946

Query: 197  FQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLG 256
                +S +  E    S    S+P  T ++    ++    +S+ PT  +   +  ++  L 
Sbjct: 947  ---TSSGVSEE----SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT-SHSSQGSTEATLS 998

Query: 257  LVAPLASAAEVSST----APVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPF 312
              +  AS+    ST    +P   +    P    +S     +T +HS   +  T++ PA  
Sbjct: 999  PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 1058

Query: 313  TAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPS-----HFLASATAAAR 367
            T+A         +S P+++   P P         +       PS     HF AS+T   R
Sbjct: 1059 TSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR 1118

Query: 368  AQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKT- 426
            ++                       S++ HSS            P ++   L  + S T 
Sbjct: 1119 SEE----------------------STTVHSS------------PGATGTALFPTRSATS 1144

Query: 427  --VSEDGPQAVSSGHTRCEKRADTAPGQTLAPRG----GSPRSQASRPHINSALHVEDKA 480
              V E     +SSG T       +     L+ +      SPRS  +     S        
Sbjct: 1145 VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE 1204

Query: 481  ISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPST 540
             S    SRP  T ++   G++  P VS+  T  A    P S D    L+P ++ A   S 
Sbjct: 1205 ESTTSHSRPGSTHTTAFPGSTTMPGVSQEST--ASHSSPGSTDT--TLSPGSTTAS--SL 1258

Query: 541  APVSGKKHRPPGPLFSSSDPLPATSSHSRD-SAQVTSMIPAPFTAASRDAGMRRTRPGT- 598
             P S   H  PG   ++  P   T+S   + S  V S   +P T  S      R    T 
Sbjct: 1259 GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318

Query: 599  --SAPAAAAAAPPPSTLNPTSGSLLNAVDEGPS-----HFLASATAAARARRSQVRYNQR 651
              S P++    P P T       L       PS     HF AS+T   R+  S   ++  
Sbjct: 1319 FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1378

Query: 652  SQTSRTRSCLKRNASSSSHSSTEGL-QELKRRRGPASSHCQLALSSSNTVSEDGPQAVSS 710
              T+ T         S + S+T GL +E         S   +    S+T S    ++ +S
Sbjct: 1379 VATATT--------PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTS 1430

Query: 711  RDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLAT 770
              +      + P  T A     P S  S P   +  H  + + +  R    + + SS  T
Sbjct: 1431 HSSTTHTISSPPSTTSA-LVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDT 1489

Query: 771  GASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHR--------- 821
              +G  P+    T   +     ++     ++P +    ++STA   G   +         
Sbjct: 1490 --NGITPLPAHFTTSGR----IAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDL 1543

Query: 822  --PPGPLFSSSDP-----LPATSSHSGDSAQDTSLIPAP 853
               P   + S  P      PA+SS SG + + T+   +P
Sbjct: 1544 VGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSP 1582



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 144/654 (22%), Positives = 229/654 (35%), Gaps = 107/654 (16%)

Query: 281  PGPLFSSSDPLP-ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPP-- 337
            P P  +++ P+  +T+ H    +  T+  PA  T +          S+P A+   P    
Sbjct: 635  PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 694

Query: 338  STLNPTSGSLLNAVDGGPSHFLA---SATAAARAQRSEVRYNQRSQISRTRSCLKRNASS 394
            ST +    S  + +  G +       S T    ++ S   Y+     + T S     +  
Sbjct: 695  STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 754

Query: 395  SSHSSTEGLPELKRRRGPASSHCQLAHSSSKT--VSEDGPQAVSSGHTRCEKRADTAPGQ 452
                ST        R  P S+H  ++ +S+ T  +SE+     SS     E         
Sbjct: 755  VGEESTTS------RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-FPHST 807

Query: 453  TLAPRGGSPRSQASRP-HINSALHVEDKAISDCR------PSRPSHTLSSLA---TGASR 502
            T +  G  P +  SRP   ++ L  ED   S         P  P+ T + L    T A  
Sbjct: 808  TTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL 867

Query: 503  GPPVSKAPTMDAQQDR---PKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSD 559
            G   +  P+          P      GL+     +   PS+   +     P  P  S   
Sbjct: 868  GEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS 927

Query: 560  PLPATSSHSRDSAQVTSMIPAPFTAA--SRDAGMRRTRPGTSAPAA-------AAAAPPP 610
                TS  S D+    ++ PA  T++  S ++    ++PG++   A       +  +  P
Sbjct: 928  TTFYTSPRSPDA----TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEP 983

Query: 611  STLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTR------SCLKRN 664
            +T + + GS    +  G      S TA++  ++S   ++    T  T       +     
Sbjct: 984  TTSHSSQGSTEATLSPG------STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVE 1037

Query: 665  ASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQ 724
            AS+ +HSST  L        PASS     L   +T  +  P   SS DT      + PG 
Sbjct: 1038 ASTPTHSSTGSLHTTLT---PASS-TSAGLQEESTTFQSWP---SSSDT----TPSPPGT 1086

Query: 725  TLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSR----------------PSHTLSSL 768
            T AP   S  +  SRP      H    + +  R                   P+ + +S+
Sbjct: 1087 TAAPVEVST-TYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSV 1145

Query: 769  ATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV--------------APLASAAEVSS-TA 813
              G     P+S   T       P S    GL                 L+ A+  SS  +
Sbjct: 1146 LVGEPTTSPISSGSTETTAL--PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVS 1203

Query: 814  PVSGKKHRPPGPL----FSSSDPLP-----ATSSHSGDSAQDTSLIPAPFTPAS 858
              S   H  PG      F  S  +P     +T+SHS   + DT+L P   T +S
Sbjct: 1204 EESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASS 1257



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 129/604 (21%), Positives = 209/604 (34%), Gaps = 68/604 (11%)

Query: 270 TAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAP- 328
           ++P S      P  + SS     +T+SHSR  +  T+  P   T          + S+P 
Sbjct: 128 SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPG 187

Query: 329 -----------AAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQ 377
                       A++  P  +T +   GS    +   P +  AS    A         + 
Sbjct: 188 PTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTL--LPDNTTASGLLEASMPVHSSTRSP 245

Query: 378 RSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSS 437
            + +S   S  ++  S++ HS     P  K  R PA      A     T S   P ++ +
Sbjct: 246 HTTLSPAGSTTRQGESTTFHS----WPSSKDTR-PAPPTTTSAFVEPSTTSHGSPSSIPT 300

Query: 438 GHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLA 497
            H             T +       +  S P     +H  +   SD    R   + +S  
Sbjct: 301 THISAR--------STTSGLVEESTTYHSSPGSTQTMHFPE---SDTTSGRGEESTTS-- 347

Query: 498 TGASRGPPVSKAP-TMDAQQDRPKSQDCLGLLAPLASA-AELPSTAPVSGKKHRPPGPLF 555
             +S    +S AP T  A  + P S       +P ++A    P ++  SG+         
Sbjct: 348 -HSSTTHTISSAPSTTSALVEEPTSYHS----SPGSTATTHFPDSSTTSGRSEE------ 396

Query: 556 SSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNP 615
                  +T+SHS   A  T ++PA  T  S   G   T P  S+ +    A P ST  P
Sbjct: 397 -------STASHSSQDATGTIVLPARST-TSVLLGESTTSP-ISSGSMETTALPGSTTTP 447

Query: 616 TSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEG 675
                       P    + AT  + A  +    ++ S TSR+R       +    ++T G
Sbjct: 448 GLSERSTTFHSSPR---SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPG 504

Query: 676 LQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTA--PGQTLAPRGGSP 733
           L         +       L  ++T +    Q  ++  +     DTA  PG T A   G  
Sbjct: 505 LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQE 564

Query: 734 RSQ-ASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASG-GPPVSKAPTMDAQQDRP 791
            +   S P         D   S       +   SS  +  +   P  S +P +  +    
Sbjct: 565 STTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAF 624

Query: 792 KSQDCLGLVAPLASAAEVSSTAPV--SGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSL 849
           ++        P   +   ++TAPV  S   HR PG   + +   PA+S+ SG S + T  
Sbjct: 625 QTHPASTHTTP---SPPSTATAPVEESTTYHRSPGS--TPTTHFPASSTTSGHSEKSTIF 679

Query: 850 IPAP 853
             +P
Sbjct: 680 HSSP 683



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 185/881 (20%), Positives = 298/881 (33%), Gaps = 88/881 (9%)

Query: 39   GLSPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGL-PGLKQR 97
            G +P    P    T  H++ S I ++    +  T SS          S+T  + PG  + 
Sbjct: 656  GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 715

Query: 98   RGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPR 157
                 S     LS + T     P++ +   T    A+ T+ G      G    +  S+P 
Sbjct: 716  TTLPGSTTTPGLSEASTTFYSSPRSPT---TTLSPASMTSLGV-----GEESTTSRSQPG 767

Query: 158  RRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQR-INSALHVEDKAISDCRP 216
                 + P+    P +     E    V +      +   F     +++H E+      RP
Sbjct: 768  STHSTVSPASTTTPGLS----EESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRP 823

Query: 217  SRPSHTLSSLATGASGGPPVSKA-PTMDAQQDRPKSQDCLGLVAPLASA--AEVSSTAPV 273
            +    TL +  +  SG    S A P   A           GL A L +A   E S+T P 
Sbjct: 824  ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT-------GLPATLTTADLGEESTTFPS 876

Query: 274  S-GKKQRPPGPLFSSSDPLPATSSHSR--DSAQVTSMIPAPFTAASRDAGMRRTRSAPAA 330
            S G       P  S++  L   S+ SR   S+  T+ +P   T  S         ++P +
Sbjct: 877  SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 936

Query: 331  AAAAPPPSTLNPTSGSLLNAVDG---GPSHFLASATAAARAQRSEVRYNQRSQISRTRSC 387
              A   P+T   +  S  ++      G +H  A   +   +  S+      S    T + 
Sbjct: 937  PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 996

Query: 388  LKRNASSSS---------HSS--------------TEGLPELKR--RRGPASSHCQLAHS 422
            L   ++++S         HSS              T GL E          S H  L  +
Sbjct: 997  LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 1056

Query: 423  SSKTVSEDGPQAVSSGHTRCEKRADTAP---GQTLAPRGGSPRSQASRPHINSALHVEDK 479
            SS +    G Q  S+        +DT P   G T AP   S  +  SRP      H    
Sbjct: 1057 SSTSA---GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVST-TYHSRPSSTPTTHFSAS 1112

Query: 480  AISDCRPSRPSHTLSSL-ATGASRGPPVSKA------PTMDAQQDRPKSQDCLGLLAPLA 532
            + +  R    +   SS  ATG +  P  S        PT             L      A
Sbjct: 1113 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTA 1172

Query: 533  SAAELPST---APVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFT--AASR 587
              +E  +T   +P S      P    SS     +T+SHSR  +  T+  P   T    S+
Sbjct: 1173 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1232

Query: 588  DAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVR 647
            ++    + PG++    +  +   S+L P S +  ++     +  L   T A+    +   
Sbjct: 1233 ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 1292

Query: 648  YNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQA 707
             +  + +  T      + +    S+T       +   PA      A    +T S   P +
Sbjct: 1293 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS 1352

Query: 708  VSSRDTRCEKADTAPGQTLAPRGGSPRSQASRP---RINSALHVEDKAISDCRPSRPSHT 764
              +             +       SP + A+ P   R  ++  VE+       P   + T
Sbjct: 1353 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGS-TQT 1411

Query: 765  L----SSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKH 820
            +    SS A+G S     S + T       P +   L +  P +  +   S A      H
Sbjct: 1412 MHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL-VEEPTSYHSSPGSIATT----H 1466

Query: 821  RPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPASRDA 861
             P     S      +T+SHS       + +PA FT + R A
Sbjct: 1467 FPESSTTSGRSE-ESTASHSSPDTNGITPLPAHFTTSGRIA 1506



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 131/597 (21%), Positives = 207/597 (34%), Gaps = 92/597 (15%)

Query: 286 SSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPT-- 343
           S++  L  TS HS   +  T+      T + R    + + S+P A A    P+   P+  
Sbjct: 32  STTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVL 91

Query: 344 -SGSLLNAVDGGPSHFLA---SATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSS 399
              S  + +  G     A   S T    +++S   Y+       T       +S  S  S
Sbjct: 92  VGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEES 151

Query: 400 TEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPR-G 458
           T           P S+H   A   S T+     ++ +S  +        +PG T A   G
Sbjct: 152 TTS------HSRPGSTH-TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG 204

Query: 459 GSPRSQASRPHINSALHVEDKAISD--CRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQ 516
               +  SRP       + D   +      S P H+       ++R P  + +P      
Sbjct: 205 PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS-------STRSPHTTLSPA----- 252

Query: 517 DRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTS 576
                    G       +    S    S K  RP  P  +S+   P+T+SH   S+  T+
Sbjct: 253 ---------GSTTRQGESTTFHSWP--SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT 301

Query: 577 MIPAPFTAAS--RDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLAS 634
            I A  T +    ++    + PG++         P S      G          +H ++S
Sbjct: 302 HISARSTTSGLVEESTTYHSSPGSTQTMHF----PESDTTSGRGEESTTSHSSTTHTISS 357

Query: 635 A--TAAARARRSQVRYNQRSQTSRTR------SCLKRNASSSSHSSTEGLQELKRRRGPA 686
           A  T +A        ++    T+ T       +  +   S++SHSS +    +     PA
Sbjct: 358 APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL---PA 414

Query: 687 SSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSAL 746
            S   + L  S T     P +  S +T        PG T  P G S RS        +  
Sbjct: 415 RSTTSVLLGESTT----SPISSGSMET-----TALPGSTTTP-GLSERS--------TTF 456

Query: 747 HVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGL-----VA 801
           H          P  P+ TLS  +T +SG   VS+  T    + RP S             
Sbjct: 457 H--------SSPRSPATTLSPASTTSSG---VSEEST--TSRSRPGSTHTTAFPDSTTTP 503

Query: 802 PLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPAS 858
            L+  +  S ++P S      P    +S     +T+SHS   + DT+L P   T  S
Sbjct: 504 GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALS 560


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 138/637 (21%), Positives = 218/637 (34%), Gaps = 97/637 (15%)

Query: 231 SGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAP--------VSGKKQRPPG 282
           +G PP   A T    +  P+         P   +A V  T P         +  KQ P  
Sbjct: 11  AGAPPAVVARTPPEPRPSPEGDPS---PPPPPMSALVPDTPPDTPPAMKNATSSKQLPLE 67

Query: 283 PLFSSSD--PLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTL 340
           P   S    P PA       S++  S  P P     RDA   R  S P+  A   P S  
Sbjct: 68  PESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAV--PASDS 125

Query: 341 NPTSGSLLNAVDGGPSHFLASATAAARA--------------QRSEVRYNQRSQISRTRS 386
            PT   +  A   G  H LA      RA              ++++    ++ Q  R R 
Sbjct: 126 PPTKQEVKKA---GERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRL 182

Query: 387 CLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRA 446
             +R  +    ++ E     K  +        +  S  KT +E           R ++ +
Sbjct: 183 EEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAE----------IRQQRWS 232

Query: 447 DTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
                   +P   +  S+ S   +N   HV+  +I + R S+ S TL +     SR   +
Sbjct: 233 WAGALHHSSPGHKTSGSRCSVSAVNLPKHVD--SIINKRLSKSSATLWN---SPSRNRSL 287

Query: 507 SKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRP-PGPLFSSSDPLPATS 565
             +    +  DR  +   L  LA   SA  LP      G+   P  GP +  +       
Sbjct: 288 QLSAWESSIVDRLMT-PTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAG------ 340

Query: 566 SHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAP----AAAAAAPPPSTLNPTSGSLL 621
                             + +R     RT P  + P    +A+A+   P ++  +     
Sbjct: 341 -----------------ASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCA 383

Query: 622 NAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKR 681
            A + G      +  + A  RR      + S   +     K   +    S+    + LK+
Sbjct: 384 PAGERGERRKPNAGGSPAPVRRRP----EASPVQKKEKKDKERENEKEKSALARERSLKK 439

Query: 682 RRG-PASSHCQLALSSSNTVSEDGPQAVSSRDTRCEK-----ADTAPGQTLAPRGGSPRS 735
           R+  PAS   +L+ S+++ +S       SS  T   +         PG TL P+  SPR 
Sbjct: 440 RQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRG 499

Query: 736 QASRPR-----------INSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTM 784
             + P+             SA   EDK+ S  R S    + +  +   S  P  + AP  
Sbjct: 500 TTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQ 559

Query: 785 DAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHR 821
             Q       D   L +P A A  V+ + P++G   R
Sbjct: 560 KEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDR 596



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 62/246 (25%), Positives = 87/246 (35%), Gaps = 43/246 (17%)

Query: 94  LKQRRG-PASSRCQLTLSYSKTVS---EDRPQAVS-SGHTRCEKAADTAPGQTLAPRGGS 148
           LK+R+  PAS R +L+ S +  +S   + RP + S S H          PG TL P+  S
Sbjct: 437 LKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPS 496

Query: 149 PRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVED 208
           PR   + P+ R       RR E     P                         SA   ED
Sbjct: 497 PRGTTASPKGR------VRRKEEAKESP-------------------------SAAGPED 525

Query: 209 KAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVS 268
           K+ S  R S    + +  +   S  P  + AP    Q       D   L +P A A  V+
Sbjct: 526 KSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVT 585

Query: 269 STAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAP 328
            + P++G   R       +     A     R+  +           A RD  MR  + A 
Sbjct: 586 PSKPMAGTTDREEATRLLAEKRRQAREQREREEQERR-------LQAERDKRMREEQLAR 638

Query: 329 AAAAAA 334
            A A A
Sbjct: 639 EAEARA 644


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 156/713 (21%), Positives = 249/713 (34%), Gaps = 99/713 (13%)

Query: 204  LHVEDKAISDCRPSRPSH--TLSSLATGASGGPPVSKAPTMDAQQDRP-----KSQDCLG 256
            LHV D + +    + P    +LSS++TG +   PV+   +       P      S    G
Sbjct: 1153 LHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTG 1212

Query: 257  LVAPL--ASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTA 314
               PL    A+ VS+    S     P       + PLP T + S  + Q TS++    ++
Sbjct: 1213 HATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSS 1272

Query: 315  ASR--DAGMRRTRSAPAAAAAAPPPSTLNPTSGSL----------LNAVDGGPSHFL--A 360
             S      +  T ++ A+     P    +P+S S           L++   G +  L   
Sbjct: 1273 VSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVT 1332

Query: 361  SATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLA 420
            S ++A+    + +     S +S   +       +SS S+ +  P       P +S   ++
Sbjct: 1333 SPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPL------PVTSLSSVS 1386

Query: 421  HSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQT--LAPRGGSPRSQASRPHINS-ALHVE 477
               +  +    P + S+GH       DT+   T    P   +  S  S  H  S  + + 
Sbjct: 1387 TGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIP 1446

Query: 478  DKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRP-----KSQDCLGLLAPLA 532
              A +      P    SS +TG +    V+   ++      P      S    G + PL 
Sbjct: 1447 SAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLH 1506

Query: 533  SAAELPSTAPVSGKKHRPPGPLFSSSD-------PLPATSSHSRDSAQVTSMIPAPFT-A 584
              +  PS+A      H  P P+ S S        PLP TS  S  +   T   P P T A
Sbjct: 1507 VTS--PSSASTG---HATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTT---PLPVTDA 1558

Query: 585  ASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRS 644
            +S   G     P TS  +A+     P  +  TS +  +  D  P    + ++A+      
Sbjct: 1559 SSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSA--SKGDTTPLPVTSPSSAS------ 1610

Query: 645  QVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDG 704
                     T  T      + SS+S   T  L        P ++   L+   +  +    
Sbjct: 1611 ---------TGHTTPLPVTDTSSASTGDTTPL--------PVTNASSLSTGHATPLHVTS 1653

Query: 705  PQAVSSRD------TRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRP 758
            P + S+        T    A T     L   G S  +     R+     V   +     P
Sbjct: 1654 PSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRL-PVTDVSSASTGQATP 1712

Query: 759  SRPSHTLSSLATGASGGPPVSKAPTMDAQQDRP-KSQDCLGLVAPLASAAEVSSTAPVSG 817
              P  +LSS++TG +   PV+   +       P    D        A+   V+ T+ VS 
Sbjct: 1713 -LPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVS- 1770

Query: 818  KKHRPPGPLFSSSDP-------LPATSSHSGDSAQDTSLIPAPFT-PASRDAG 862
              H  P P+   S         LP T   S  + Q    IP P T P+S   G
Sbjct: 1771 TAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQ---AIPLPVTSPSSASTG 1820



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 171/859 (19%), Positives = 284/859 (33%), Gaps = 116/859 (13%)

Query: 51   QTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLS 110
            QT+ H  S      +T  T+  S++T      +S +STG    L       +    ++  
Sbjct: 951  QTETHTLSPS-GSGKTFTTALISNATPLPVTYASSASTGHTTPLH-----VTDASSVSTG 1004

Query: 111  YSKTVSEDRPQAVSSGHTRCEKAADTAPGQT--LAPRGGSPRSQASRPRRRKIPLLPSRR 168
            ++  +    P +VS+GHT      DT+   T  + P   +  S AS      +P+  +  
Sbjct: 1005 HATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSS 1064

Query: 169  GEP--LMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHT---- 222
                 +   P   L    T +   L          S  H     ++D       HT    
Sbjct: 1065 ASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSA--STGHATSLPVTDTSSVSTGHTTPLP 1122

Query: 223  ---LSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQR 279
                SS +TG +   PV+   ++      P     L +    +++   ++  PV+     
Sbjct: 1123 VTDTSSASTGHATSLPVTDTSSVSTGHTTP-----LHVTDASSASTGQATPLPVTSLSSV 1177

Query: 280  PPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPST 339
              G     + PLP TS  S  +   T ++    ++AS         + P     A   ST
Sbjct: 1178 STG----DTTPLPVTSPSSASTGHATPLLVTDTSSASTG------HATPLPVTDASSVST 1227

Query: 340  LNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSS 399
             + TS  +           + SA +        V     +   +  S L  + SS S   
Sbjct: 1228 DHATSLPVT----------IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGD 1277

Query: 400  TEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHT--------RCEKRADTAPG 451
            T  LP +      ++ H    H +S       P + S+GH               DT P 
Sbjct: 1278 TTPLP-VTSTSSASTGHVTPLHVTS-------PSSASTGHATPLPVTSLSSASTGDTMPL 1329

Query: 452  QTLAPRGGSPRSQASRPHINSA---------LHVEDKAISDCRPSR--PSHTLSSLATGA 500
               +P   S       P  +++         LHV D + +    +   P  +LSS++TG 
Sbjct: 1330 PVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGD 1389

Query: 501  SRGPPVSKAPTMDAQQDRP-----KSQDCLGLLAPL--ASAAELPSTAPVSGKKHRPPGP 553
            +   PV+   +       P      S    G   PL    A+ + +    S     P   
Sbjct: 1390 TTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAA 1449

Query: 554  LFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTL 613
                + PLP T + S  + Q TS++    ++ S   G     P TS  +A+     P  +
Sbjct: 1450 STGHTTPLPVTDTSSASTGQATSLLVTDTSSVS--TGDTTPLPVTSTSSASTGHVTPLHV 1507

Query: 614  NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSST 673
               S +        P   L+SA+                 T  T      + SS+S   T
Sbjct: 1508 TSPSSASTGHATPLPVTSLSSAS-----------------TGDTMPLPVTSPSSASTGDT 1550

Query: 674  EGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDT-RCEKADTAPGQTLAPRGGS 732
              L               L ++S ++ S      +   DT    K DT P    +P   S
Sbjct: 1551 TPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSAS 1610

Query: 733  PRSQASRPRINSA---------LHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPT 783
                   P  +++         L V + +      + P H  S  +       P+    T
Sbjct: 1611 TGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTST 1670

Query: 784  MDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDS 843
              A           GL    ++  + ++  PV+       G     + PLP TS  S  S
Sbjct: 1671 SSASTGHATPLPVTGL---SSATTDDTTRLPVTDVSSASTG----QATPLPVTSL-SSVS 1722

Query: 844  AQDTSLIPAPFTPASRDAG 862
              DT+ +P   +P+S   G
Sbjct: 1723 TGDTTPLPVT-SPSSASTG 1740



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 175/880 (19%), Positives = 297/880 (33%), Gaps = 119/880 (13%)

Query: 72   TSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCE 131
            T  +T      +  +STG    L     P ++   L+  ++ ++    P + S+GH    
Sbjct: 2507 TGHTTPLPVTDTPSASTGDTTPL-----PVTNASSLSTRHATSLHVTSPSSASTGHATSL 2561

Query: 132  KAADTAPGQT--LAPRGGSPRSQASRPRRRKIPL-----LPSRRGEPLMMPPPLELGYRV 184
               DT+   T    P   +  S AS      +P+       + +  PL +          
Sbjct: 2562 PVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGD 2621

Query: 185  TAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTL--SSLATGASGGPPVSKA--- 239
            T      +  +A     + L V + +      + P H    SS +TG +   PV+ A   
Sbjct: 2622 TTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSV 2681

Query: 240  --------PTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPG-----PLFS 286
                    P  DA          L +  P ++++  ++  PV+       G     P+  
Sbjct: 2682 STGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTD 2741

Query: 287  SSD-------PLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPST 339
            +S        PLP T + S  +   T   P P T+ S       T   P    ++     
Sbjct: 2742 ASSVSTGHATPLPVTDASSVSTGHAT---PLPLTSLS-SVSTGDTTPLPVTDTSSASTGQ 2797

Query: 340  LNPTSGSLLNAVDGGPSHFL----ASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSS 395
              P   + L++V  G +  L     S+ +   A    V     +           + SS+
Sbjct: 2798 ATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSA 2857

Query: 396  SHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSE--------------DGPQAVSSGHTR 441
            S      LP         +S   + H++S  V++                P + S+GH  
Sbjct: 2858 STGHATLLPVTD------TSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHAT 2911

Query: 442  CEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSH-------TLS 494
                 DT+   T    G +     + P   S  H     ++D   +   H       +LS
Sbjct: 2912 PLPVTDTSSAST----GHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLS 2967

Query: 495  SLATGASRGPPVSKAPTMDAQQDRP-KSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGP 553
            S++TG +   PV+   +       P    D        A+A  + ST+  S     P   
Sbjct: 2968 SVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPV 3027

Query: 554  LFSSS------DPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAA 607
              +SS       PLP TS  S  +   T   P P T+ S  A      P     A++A+ 
Sbjct: 3028 TDTSSASTGQATPLPVTSLSSVSTGDTT---PLPVTSPS-SASTGHATPLLVTDASSAST 3083

Query: 608  PPPSTLNPTSGSLLNAVDEGPSHFLA-SATAAARARRSQVRYNQRSQTSRTRSCLKRNAS 666
               + L  TS S ++  D  P    + S+ +   A    V     + T  T S    + S
Sbjct: 3084 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTS 3143

Query: 667  SSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRD-TRCEKADTAPGQT 725
            S+    T  L               L ++ +++VS      +   D +        P   
Sbjct: 3144 SAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHV 3203

Query: 726  LAPRGGS-------PRSQASRPRINSALHVEDKAISDCRPS----RPSHTLSSLATGASG 774
             +P   S       P +  S      A  +    +S          P   +SS +TG + 
Sbjct: 3204 TSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQAT 3263

Query: 775  GPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK-----HRPPGPLFSS 829
              PV+   ++      P     L + +P +++   ++  PV+        H  P P+ S+
Sbjct: 3264 PLPVTNTSSVSTGDTMP-----LPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTST 3318

Query: 830  SD-------PLPATSSHSGDSAQDTSLIPAPFTPASRDAG 862
            S        PLP T + S  S  DT+ +P   +P+S   G
Sbjct: 3319 SSASTGHTTPLPVTDTSSA-STGDTTPLPVT-SPSSASTG 3356



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 145/670 (21%), Positives = 234/670 (34%), Gaps = 115/670 (17%)

Query: 237  SKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPAT-- 294
            SK  T  +Q + P +    G    L +    + TA   G   R P  + +  +P   T  
Sbjct: 494  SKGHTTWSQTELPSTST--GAATRLVTGNPSTGTA---GTIPRVPSKVSAIGEPGEPTTY 548

Query: 295  SSHSRDSAQVTSM-IPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNA--- 350
            SSHS    + T       +T  +   G     S+P+ +      +  +P+S  +L+    
Sbjct: 549  SSHSTTLPKTTGAGAQTQWTQETGTTG-EALLSSPSYSVTQMIKTATSPSSSPMLDRHTS 607

Query: 351  --VDGGPS--HFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPEL 406
              +   PS  H    +T+ +  +   V     +Q  +T         S +  S   + + 
Sbjct: 608  QQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQ------ESQTTRSVSPMTDT 661

Query: 407  KRRRGPASSHCQLAHSSSKTVSED----------GPQAVSSGH-----TRCEKRADTAPG 451
            K    P SS     HS S+ V +D           P     GH     T   + A ++  
Sbjct: 662  KTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHD 721

Query: 452  QTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPT 511
             TL P GG+  S+        AL + +  +S   P  P    +S    AS  P  + A T
Sbjct: 722  ATLGPSGGTSLSK------TGALTLANSVVS--TPGGPEGQWTS--ASASTSPDTAAAMT 771

Query: 512  MDAQQDRPKSQDCLGLLAPLASAAE-------LPSTAPVSGKKHRPPGPLFSSSDPLPAT 564
               Q +  ++        P +S +         PS++  SG        + +S +    +
Sbjct: 772  HTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFS 831

Query: 565  SSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAV 624
            S+ SRDS    S       +AS  A               A++  P T +PT   L  A 
Sbjct: 832  SNPSRDSHTTQSTTELLSASASHGA--------IPVSTGMASSIVPGTFHPT---LSEAS 880

Query: 625  DEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRG 684
              G     +S T+ + + +     ++ +QT RTR+                       RG
Sbjct: 881  TAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRT----------------------SRG 918

Query: 685  PASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINS 744
              S    LA  +++T S   P   S   T      T    TL+P G       +     +
Sbjct: 919  --SDTISLASQATDTFSTVPPTPPSITSTGLTSPQTET-HTLSPSGSGKTFTTALISNAT 975

Query: 745  ALHVEDKAISDCRPSRPSHT--LSSLATGASGGPPVSKAPTMDAQQDRP-----KSQDCL 797
             L V   + +    + P H    SS++TG +   PV+   ++      P      S +  
Sbjct: 976  PLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSEST 1035

Query: 798  GLVAPLA----SAAEVSSTAPV-------SGKKHRPPGPLFSSSD-------PLPATSSH 839
            G V PL     S+A    + P+       +   H  P P+ S S        PLP T + 
Sbjct: 1036 GHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTS 1095

Query: 840  SGDSAQDTSL 849
            S  +   TSL
Sbjct: 1096 SASTGHATSL 1105



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 152/692 (21%), Positives = 236/692 (34%), Gaps = 110/692 (15%)

Query: 217  SRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGK 276
            S P    SS +TG +   PV+   +    Q  P     L + +P +++   +    V+  
Sbjct: 2176 SLPVTDTSSASTGHATPLPVTDTSSASTGQATP-----LPVTSPSSASTGHAIPLLVTDT 2230

Query: 277  KQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPP 336
                 G     + PLP TS  S  +   T   P P T AS  +    T S P  + ++  
Sbjct: 2231 SSASTG----QATPLPVTSLSSASTGDTT---PLPVTDASSVSTGHAT-SLPVTSLSSVS 2282

Query: 337  PSTLNP---TSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNAS 393
                 P   TS S  +     P H +  A++A+    + +     S  S   +      S
Sbjct: 2283 TGDTTPLPVTSPSSASTGHATPLH-VTDASSASTGHATPLPVTSLSSASTGDTTPLPVTS 2341

Query: 394  SSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAV------SSGHTRCEKRAD 447
             SS S+    P              +  +SS +  +  P  V      SSGHT      D
Sbjct: 2342 PSSASTGHATP------------LHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTD 2389

Query: 448  TAPGQT--LAPRGGSPRSQASRPHINSALHVEDKAISDCRPSR----PSHTLSSLATGAS 501
             +   T    P   +  S AS  H   A H+    +S          P   +SS +TG +
Sbjct: 2390 ASSASTGDTTPLPVTDTSSASTGH---ATHLPVTGLSSASTGDTTRLPVTNVSSASTGHA 2446

Query: 502  RGPPVSKAPTMDAQQDRP-----KSQDCLGLLAPL----------ASAAELPSTAPVSGK 546
               PV+   +       P      S    G   PL               LP T+P S  
Sbjct: 2447 TPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSAS 2506

Query: 547  K-HRPPGPLFSS-------SDPLPATSSHSRDSAQVTSM-IPAPFTAASRDAGMRRTRPG 597
              H  P P+  +       + PLP T++ S  +   TS+ + +P +A++   G   + P 
Sbjct: 2507 TGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSAST---GHATSLPV 2563

Query: 598  TSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRT 657
            T   AA+     P  +  TS +        P     SA +  +A    V     + T  T
Sbjct: 2564 TDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSA-STGQATPLPVTDTSSASTGDT 2622

Query: 658  RSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEK 717
                  + SS+S      L        P ++   ++   +  +    P + S+  T    
Sbjct: 2623 TPLPVTDTSSASTGHATPL--------PVTNTSSVSTGHATPLHVTSPSSASTGHTTPLP 2674

Query: 718  ADTAPGQTLAPRGGSPRSQASRPRINSA----LHVEDKAISDCRPSRPSHTLSSLATGAS 773
               A   +       P + AS      A    + +   A S      P    SS++TG +
Sbjct: 2675 VTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHA 2734

Query: 774  GGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSD-- 831
               PV+ A ++      P          P+  A+ VS+        H  P PL S S   
Sbjct: 2735 TSLPVTDASSVSTGHATP---------LPVTDASSVST-------GHATPLPLTSLSSVS 2778

Query: 832  -----PLPATSSHSGDSAQDTSLIPAPFTPAS 858
                 PLP T + S  + Q T   P P T  S
Sbjct: 2779 TGDTTPLPVTDTSSASTGQAT---PLPVTSLS 2807



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 168/837 (20%), Positives = 283/837 (33%), Gaps = 78/837 (9%)

Query: 57   QSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVS 116
            Q++ +    TS  S T  +T      +S +STG    L     P +S   ++   +  + 
Sbjct: 3005 QATALPVTSTSSAS-TGDTTPLPVTDTSSASTGQATPL-----PVTSLSSVSTGDTTPLP 3058

Query: 117  EDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPP 176
               P + S+GH       D +   T         S +S       PL       P+  P 
Sbjct: 3059 VTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPL-------PVTSPS 3111

Query: 177  PLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPV 236
                G+  +         +     +  +     A +    S P    SS +TG +    V
Sbjct: 3112 SASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLV 3171

Query: 237  SKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSS 296
            ++  ++      P       L+   AS+A      P+      P       + P+P T +
Sbjct: 3172 TETSSVSTGHATP-------LLVTDASSASTGHATPLHVTS--PSSASTGDTTPVPVTDT 3222

Query: 297  HSRDSAQVTSMIPAPFTAASRDAGMRRTRS--APAAAAAAPPPSTLNPTSGSLLNAVDGG 354
             S  +   T   P P T  S  +    TR      ++A+    + L  T+ S ++  D  
Sbjct: 3223 SSVSTGHAT---PLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTM 3279

Query: 355  PSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPAS 414
            P   + S ++A+    + +     S  S   +      S+SS S+    P       P +
Sbjct: 3280 PLP-VTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPL------PVT 3332

Query: 415  SHCQLAHSSSKTVSEDGPQAVSSGHTR-----CEKRADTAPGQTLAPRGGSPRSQASRPH 469
                 +   +  +    P + S+GHT          A T    TL   G S    AS  H
Sbjct: 3333 DTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGAS---SASTGH 3389

Query: 470  INSALHVEDKAISDCRPSR-PSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLL 528
                   +  ++S    +  P  +LSS++TG +   PV+ A +    Q  P     L  +
Sbjct: 3390 ATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSV 3449

Query: 529  APLASAAELPSTAPVSGKKHRPPGPLFSSSDP-------LPATSSHSRDSAQVTSMIPAP 581
            +   +   L + A      H  P P+  +S         LP T + S  + Q T   P P
Sbjct: 3450 STGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQAT---PLP 3506

Query: 582  FTA-ASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAAR 640
             T+ +S   G       T A + +     P  +  TS +        P    +SA +  +
Sbjct: 3507 VTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSA-STGQ 3565

Query: 641  ARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTV 700
            A    V     S +  T      + SS S      L               L ++S+++ 
Sbjct: 3566 ATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSA 3625

Query: 701  SEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSR 760
            S     A     T      T     L     S  S        + L V D + +    + 
Sbjct: 3626 STG--HATPLLVTDASSVSTGHATPLPVTDASSASTGD----TTPLPVTDTSSASTGQAT 3679

Query: 761  --PSHTLSSLATGASGGPPVSKAPTMDAQQDRP---------KSQDCLGL--VAPLASAA 807
              P  +LSS++TG +   PV+ A +       P          + D + L   +P +++ 
Sbjct: 3680 PLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAST 3739

Query: 808  EVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPASRDAGVR 864
              ++  PV+G      G     + PLP T + S  +   T L     + AS D   R
Sbjct: 3740 GHATPLPVTGLSSASTG----DTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTR 3792



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 149/675 (22%), Positives = 226/675 (33%), Gaps = 116/675 (17%)

Query: 202  SALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPL 261
            S+ H     ++D       H  S L T AS        P      +   + D   L    
Sbjct: 1850 SSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTD 1909

Query: 262  ASAAEV--SSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDA 319
            AS+     +++ PV+       G     + PLP TS  S  S   T   P P T AS   
Sbjct: 1910 ASSVSTGHATSLPVTSLSSASTG----DTTPLPVTSPSSASSGHTT---PLPVTDASSVP 1962

Query: 320  GMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRS 379
                T S P   A++       P   +  ++V  G       AT       S V   Q +
Sbjct: 1963 TGHAT-SLPVTDASSVSTGHATPLPVTDASSVSTG------HATPLPVTDTSSVSTGQAT 2015

Query: 380  QISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGH 439
             +  T      + SS+S   T  LP              +  +SS +  +D P  V+S  
Sbjct: 2016 PLPVT------SLSSASTGDTTPLP--------------VTDTSSASTGQDTPLPVTS-- 2053

Query: 440  TRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHT-LSSLAT 498
                   DT P    +P      S AS  H    L  +  ++S    +    T  SS++T
Sbjct: 2054 LSSVSTGDTTPLPVTSP------SSASTGHATPLLVTDASSVSTGHATSLLVTDASSVST 2107

Query: 499  GASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSS 558
            G +    V+ A ++      P                 LP T+P S             +
Sbjct: 2108 GHATALHVTDASSLSTGDTTP-----------------LPVTSPSSAST--------GDT 2142

Query: 559  DPLPATSSHSRDSAQVTSMIPAPFT-AASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTS 617
             PLP T + S  +   TS+   P T  +S   G   + P T   +A+     P  +  TS
Sbjct: 2143 TPLPVTDTSSVSTGHATSL---PVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTS 2199

Query: 618  GSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQ 677
             +        P   + S ++A+      +     S  S T        +S S +ST    
Sbjct: 2200 SASTGQATPLP---VTSPSSASTGHAIPLLVTDTSSAS-TGQATPLPVTSLSSASTGDTT 2255

Query: 678  ELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQA 737
             L     P +    ++   + ++      +VS+        DT P    +P   S     
Sbjct: 2256 PL-----PVTDASSVSTGHATSLPVTSLSSVST-------GDTTPLPVTSPSSASTGHA- 2302

Query: 738  SRPRINSALHVED--KAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRP---- 791
                  + LHV D   A +      P  +LSS +TG +   PV+   +       P    
Sbjct: 2303 ------TPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVT 2356

Query: 792  -KSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSD-------PLPATSSHSGDS 843
              S    G   PL      SS++  SG  H  P P+  +S        PLP T + S  +
Sbjct: 2357 DASSVSTGDTTPL---PVTSSSSASSG--HTTPLPVTDASSASTGDTTPLPVTDTSSAST 2411

Query: 844  AQDTSLIPAPFTPAS 858
               T L     + AS
Sbjct: 2412 GHATHLPVTGLSSAS 2426



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 137/681 (20%), Positives = 236/681 (34%), Gaps = 67/681 (9%)

Query: 219  PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQ 278
            P    SS++TG +        P +        + D   L     S+A    T P+     
Sbjct: 2466 PGTDTSSVSTGHT-------TPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDT 2518

Query: 279  RPPGPLFSSSDPLPATSSHSRDSAQVTSM-IPAPFTAASRDAGMRRTRSAPAAAAAAPPP 337
              P      + PLP T++ S  +   TS+ + +P +A++  A         AA+     P
Sbjct: 2519 --PSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATP 2576

Query: 338  STLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISR--TRSCLKRNASSS 395
              +  TS +        P   +    +A+  Q + +     S  S   T      + SS+
Sbjct: 2577 LPVTSTSSASTGDTTPLP---VTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSA 2633

Query: 396  SHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLA 455
            S      LP +      ++ H    H +S       P + S+GHT      D +   T  
Sbjct: 2634 STGHATPLP-VTNTSSVSTGHATPLHVTS-------PSSASTGHTTPLPVTDASSVST-G 2684

Query: 456  PRGGSPRSQASRPHINSA----LHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPT 511
                 P + AS      A    + +   A S      P    SS++TG +   PV+ A +
Sbjct: 2685 HATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASS 2744

Query: 512  MDAQQDRPKS-QDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSS------DPLPAT 564
            +      P    D   +    A+   L S + VS     P     +SS       PLP T
Sbjct: 2745 VSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVT 2804

Query: 565  SSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPP-----------STL 613
            S  S  +   T +     ++AS           TS+ +   A P P           +TL
Sbjct: 2805 SLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATL 2864

Query: 614  NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRS----CLKRNASSSS 669
             P + +   ++    S  +   ++ +    + +     S  S   +        +++S+ 
Sbjct: 2865 LPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTG 2924

Query: 670  HSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPR 729
            H++   +          ++   +  +SS +     P  V+S  +     DT P    +P 
Sbjct: 2925 HANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSS-VSTGDTTPLPVTSPS 2983

Query: 730  GGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQD 789
              S       P  +++      A +    + P  + SS +TG +   PV+   +    Q 
Sbjct: 2984 SASTGHTTPLPVTDTS-----SASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQA 3038

Query: 790  RPKSQDCLGLVAPLASAAEVSSTAPVSGKK-HRPPGPLFSSSD-------PLPATSSHSG 841
             P     L  V+       +  T+P S    H  P  +  +S        PLP TS  S 
Sbjct: 3039 TPLPVTSLSSVS-TGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSL-SS 3096

Query: 842  DSAQDTSLIPAPFTPASRDAG 862
             S  DT+ +P   +P+S   G
Sbjct: 3097 VSTGDTTPLPVT-SPSSASTG 3116



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 138/655 (21%), Positives = 231/655 (35%), Gaps = 85/655 (12%)

Query: 219  PSHTLSSLATGASGGPPVSKAPTMDAQQDRP---------KSQDCLGL--VAPLASAAEV 267
            P  +LSS++TG +   PV+ A +       P          + D + L   +P +++   
Sbjct: 3682 PVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGH 3741

Query: 268  SSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSA 327
            ++  PV+G      G     + PLP T + S  +   T +     ++AS D    R    
Sbjct: 3742 ATPLPVTGLSSASTG----DTTPLPVTDTSSASTRHATPLPVTDTSSASTD-DTTRLPVT 3796

Query: 328  PAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSC 387
              ++A+    + L  TS S  +  D  P   +   ++ +    + +    RS  S   + 
Sbjct: 3797 DVSSASTGHATPLPVTSTSSASTGDTTPLP-VTDTSSVSTGHATSLPVTSRSSASTGHAT 3855

Query: 388  LKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRAD 447
                  +SS S+    P       P +S   ++   +  +    P + S+GH        
Sbjct: 3856 PLPVTDTSSVSTGHATPL------PVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTS 3909

Query: 448  TAPGQT--LAPRGGSPRSQASRPHINSALHVED--KAISDCRPSRPSHTLSSLATGASRG 503
            T+   T    P   +  S  S  H  + LHV     A      + P    SS +TG +  
Sbjct: 3910 TSSASTGDTTPLPVTNASSLSTGHA-TPLHVTSPSSASRGDTSTLPVTDASSASTGHATP 3968

Query: 504  PPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPA 563
             P++   ++      P     L +    +++    +  PV+       G     + PLP 
Sbjct: 3969 LPLTSLSSVSTGDTTP-----LPVTDTSSASTGQATPLPVTSLSSVSTG----DTTPLPV 4019

Query: 564  TSSHSRDSAQVTSMIPAPFT-AASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLN 622
            T   S  S   TS+   P T A+S   G     P TS  +A+     P  +  TS     
Sbjct: 4020 TIPSSASSGHTTSL---PVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS----- 4071

Query: 623  AVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRR 682
                          +A+    + +     S  S   +      S SS S+          
Sbjct: 4072 --------------SASTGHATPLPVTDTSSASTGHATPLPVTSLSSVST---------- 4107

Query: 683  RGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRI 742
             G A+     + +S++TVS D P  + +         T  G+  A       SQ     I
Sbjct: 4108 -GHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTI 4166

Query: 743  -NSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVA 801
             ++A+H    A     P  P   +S    GA  G       T+D     P  +   G   
Sbjct: 4167 PSTAMHTRSTAAP--IPILPERGVSLFPYGAGAGDLEFVRRTVDFTS--PLFKPATGF-- 4220

Query: 802  PLASAAEVSSTAPVSGKKHRPPG--PLFSSSDPLPATSSHSGDSAQDTSLIPAPF 854
            PL S+   S     +G+   P     +FS  +PLP     +G + +D   + APF
Sbjct: 4221 PLGSSLRDSLYFTDNGQIIFPESDYQIFSYPNPLP-----TGFTGRDPVALVAPF 4270


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 164/822 (19%), Positives = 276/822 (33%), Gaps = 114/822 (13%)

Query: 110 SYSKTVSEDRPQAVSSGHTRCEK---AADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPS 166
           S   +V+ D P   S+  T  E    +  T+   TL P      S  + P    +P    
Sbjct: 93  SIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVP---- 148

Query: 167 RRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAI-------SDCRPSRP 219
                  M  P E     T   +      +F+   S  +  D +        +   P+ P
Sbjct: 149 -------MSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTP 201

Query: 220 SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQR 279
             T    +T + G  P++  P    +     S+    L  P+  +  V+ +A  S     
Sbjct: 202 ESTTIPKSTNSEGSTPLTSMPASTMKV--ASSEAITLLTTPVEISTPVTISAQASSSPTT 259

Query: 280 PPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPA------AAAA 333
             GP  S+S P       S  S  +T M  +     S +A    T  A        +  A
Sbjct: 260 AEGPSLSNSAP-------SGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEA 312

Query: 334 APPPSTLNPTSGSLLNAVDGG------PSHFLASATAA-ARAQRSEVRYNQRSQISRTRS 386
           +  P+T   TS       +G       P+  +  AT+  +    + V  +     S   S
Sbjct: 313 SSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPS 372

Query: 387 CLKRNASSSS---HSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCE 443
            L   A ++S    + +EG   L               S++ T+  D    V++  +   
Sbjct: 373 SLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTA-SEAS 431

Query: 444 KRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCR--PSRP--SHTLSSLATG 499
               TA   ++A    S  S+ S P  +  +     A S+     + P  S T  + +T 
Sbjct: 432 SSPTTAEDTSIAT---STPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTE 488

Query: 500 ASRGPPVSKAPTMD----AQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLF 555
           AS  PP ++  +M     ++   P +   +  +   +S A   ST PV            
Sbjct: 489 ASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEA 548

Query: 556 SSSDPLPA-----TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPG-------TSAPAA 603
           SSS   P      TS+ S  S  +T+M  +     S +A    T P        TS+ A+
Sbjct: 549 SSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS 608

Query: 604 AAAAPPPSTLNPTS-----GSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTR 658
           +++     T  PTS     G+ + ++    +  L +++ A+    + V  N    TS   
Sbjct: 609 SSSTTAEGTSMPTSTYSERGTTITSMSVSTT--LVASSEASTLSTTPVDSNTPVTTSTEA 666

Query: 659 SCLKRNASSSSHSS---TEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRC 715
           +     A  +S  +   TEG   L       +       S+ +T   D    V++     
Sbjct: 667 TSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726

Query: 716 EKADTAPGQTL---APRGGSP----------------RSQASRPRINSALHVEDKAISDC 756
               TA G ++    P  GS                  S  S   ++++ H+     + C
Sbjct: 727 SSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASC 786

Query: 757 RPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVS 816
            P+    T   ++T + G P ++  P        P+        A   S   V S +PV+
Sbjct: 787 SPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE--------ASTLSTTPVDSNSPVT 838

Query: 817 GKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPAS 858
                       SS P PA  +    S       P    P S
Sbjct: 839 TSTE-------VSSSPTPAEGTSMPTSTYSEGRTPLTSMPVS 873



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 127/645 (19%), Positives = 216/645 (33%), Gaps = 51/645 (7%)

Query: 220  SHTLSSLATGASGGPPVSK----APTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSG 275
            S T  + A+ AS  P  ++    A +  ++   P +   +      +S A   ST PV  
Sbjct: 420  SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDS 479

Query: 276  KKQRPPGPLFSSSDPLP-----ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRT----RS 326
            K Q       SSS P        TS+ S  S  +TSM  +    AS +A    T     S
Sbjct: 480  KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS 539

Query: 327  APAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAAR-AQRSEVRYNQRSQISRTR 385
             P   ++    S+  P   S+  +     S  L +   + R    SE      +      
Sbjct: 540  TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNT 599

Query: 386  SCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKR 445
                 + +SSS ++ EG         P S++ +   + +         A S   T     
Sbjct: 600  FVTTSSEASSSSTTAEGTSM------PTSTYSERGTTITSMSVSTTLVASSEASTLSTTP 653

Query: 446  ADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPP 505
             D+    T +    S  + A    + ++ + E        P   +   SS A+  S  P 
Sbjct: 654  VDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV 713

Query: 506  VSKAP--TMDAQQDRPKSQDCLGLLAPLASAAELPSTA-PVSGKKHRPPGPLFSSSDPLP 562
             +  P  T       P + D   +     S    P T+ PVS            S+ PL 
Sbjct: 714  DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLD 773

Query: 563  -----ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRT-----RPGTSAPAAAAAAPPPST 612
                  TS+ +  S   T     P +  S  + +  +      P TS  A+  +  P  +
Sbjct: 774  TSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDS 833

Query: 613  LNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSS 672
             +P + S   +    P+   +  T+     R+ +     S T    S +   +++   +S
Sbjct: 834  NSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTS 893

Query: 673  TEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGS 732
            T      + R             SS T SE      S+         + P  T       
Sbjct: 894  TPVTNSTEAR-------------SSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSE 940

Query: 733  PRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAP---TMDAQQD 789
             R+ ++ P ++++  V     +   P+    T    +T + G  P++  P   T+ A  +
Sbjct: 941  ARTLSATP-VDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSE 999

Query: 790  RPK-SQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPL 833
                S   +    PL ++ E SS  P +     P       S PL
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPL 1044



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 155/830 (18%), Positives = 274/830 (33%), Gaps = 106/830 (12%)

Query: 50   LQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTL 109
            + T L A S     + T   S T  +T   A SSS ++ G          P S+  + + 
Sbjct: 636  VSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG-------TSMPTSTYTEGST 688

Query: 110  SYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRG 169
              +         A S   T      DT+   T +    S  + A       +P      G
Sbjct: 689  PLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA---SMPTSTPSEG 745

Query: 170  EPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATG 229
               +   P+      ++E   L        ++++ H+     + C P+    T   ++T 
Sbjct: 746  STPLTSMPVSKTLLTSSEASTLSTTP----LDTSTHITTSTEASCSPTTTEGTSMPISTP 801

Query: 230  ASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSD 289
            + G P ++  P        P+        A   S   V S +PV+   +    P  +   
Sbjct: 802  SEGSPLLTSIPVSITPVTSPE--------ASTLSTTPVDSNSPVTTSTEVSSSPTPAEGT 853

Query: 290  PLPATSSHSRDSAQVTSM-IPAPFTAASRDAGMRRT---RSAPAAAAAAPPPSTLNPTSG 345
             +P TS++S     +TSM +     A S  + +  T    S P   +     S       
Sbjct: 854  SMP-TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT 912

Query: 346  SLLNAVDG-GPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEG-- 402
            S+  +  G G +   +   +      SE R    + +  +        ++SS ++ EG  
Sbjct: 913  SMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTS 972

Query: 403  LPELKRRRGPAS------SHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAP 456
            +P      G         SH  +A+S + T+S                   T P  +  P
Sbjct: 973  IPTSTPSEGTTPLTSTPVSHTLVANSEASTLS-------------------TTPVDSNTP 1013

Query: 457  RGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQ 516
               S  + +  P                  S P+ T S  +T  +R P    + TM A  
Sbjct: 1014 LTTSTEASSPPPTAEGT-------------SMPTSTPSEGSTPLTRMP---VSTTMVASS 1057

Query: 517  DRPK-SQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSR----DS 571
            +    S        P+ + ++  S++  +     P       S PL +    +R      
Sbjct: 1058 ETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSE 1117

Query: 572  AQVTSMIPA----PFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEG 627
            A   S  P     P T ++  +    T  GTS P     +PP     P +   ++     
Sbjct: 1118 ASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP----TSPPSEGTTPLASMPVSTTLVV 1173

Query: 628  PSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPAS 687
             S     +T    ++       + S    T        S+    ST  L  +  R  P +
Sbjct: 1174 SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP-LTSMPVRHTPVA 1232

Query: 688  SHCQLALSSS--------NTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASR 739
            S     LS+S         T +E      ++  T    + T+ G TL        +  + 
Sbjct: 1233 SSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTS 1292

Query: 740  PRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDR-PKSQDCLG 798
            P  ++ L      +    P   S+ +SS  T A G    +  PT    + R P +   + 
Sbjct: 1293 PEASTLL---TTPVDTKGPVVTSNEVSSSPTPAEG----TSMPTSTYSEGRTPLTSIPVN 1345

Query: 799  LVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTS 848
                 +SA  + ST PV         P+ +S++   + ++  G S  +++
Sbjct: 1346 TTLVASSAISILSTTPVDNST-----PVTTSTEACSSPTTSEGTSMPNSN 1390



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 146/710 (20%), Positives = 246/710 (34%), Gaps = 58/710 (8%)

Query: 202  SALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPL 261
            +++ V    +     S  S T    +T  +     S +PT       P S    G   PL
Sbjct: 2400 TSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG-TTPL 2458

Query: 262  ASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGM 321
            AS   VS+T  VS +          +S P+  TS+ +  S      I  P + AS  + +
Sbjct: 2459 ASMP-VSTTPVVSSEAGTLSTTPVDTSTPM-TTSTEASSSPTTAEDIVVPISTASEGSTL 2516

Query: 322  RRTRSAPAAAAAAPPPSTLNPT----SGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQ 377
              +        A+P  STL+ T    +  ++ + +   S   A  T+   +  SE     
Sbjct: 2517 LTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPL 2576

Query: 378  RSQISRTRSCLKRNAS-------------SSSHSSTEGLPELKRRRGPASSHCQLAHSSS 424
            RS    T+      AS             ++S  ++      K    P S+  +++ S +
Sbjct: 2577 RSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLT 2636

Query: 425  KTVSEDGPQAVSSGHTRCEKRAD----------TAPGQTLAPRGGSPRS---QASRPHIN 471
              +    P A S   T      D          T+   T A     P S   + S P  N
Sbjct: 2637 SILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTN 2696

Query: 472  SALHVEDKAISDCR--PSRPSHTLSSLATG--ASRGPPVSKAPTMDAQQDRPKSQDCLGL 527
              +     A S+     + P  T + + T   AS  P  ++  +M        S     +
Sbjct: 2697 ILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSI 2756

Query: 528  LA---PLAS--AAELPSTA-----PVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSM 577
            L    P+AS  A+ + +TA     PV+        P  +    +P TS+ S  S  +TSM
Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMP-TSTPSETSTPLTSM 2815

Query: 578  IPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSL--LNAVDEGPSHFLASA 635
                   AS +AG   T P  ++     +    S+     G +  ++   EG +   +  
Sbjct: 2816 PVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIP 2875

Query: 636  TAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALS 695
             +      S+      +    +         SSS ++ EG           S+     L 
Sbjct: 2876 VSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILV 2935

Query: 696  SSNTV--SEDGPQAVSSRDTR---CEKADTAPGQTLAPRGGSPRSQASRPRIN-SALHVE 749
            S+  V  SE    + +  DTR      A+ +   T A     P S     R   +++ V 
Sbjct: 2936 STVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVS 2995

Query: 750  DKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEV 809
               ++    S  S T +  +T  +     S +PT       P S    G   PL S    
Sbjct: 2996 TMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEG-STPLTSIPVS 3054

Query: 810  SSTAPVSGKKHRPPGPLFSSSDPLPATS-SHSGDSAQDTSLIPAPFTPAS 858
            ++   +         P+ S+S  + +T  S S   A+ TS+  + ++  S
Sbjct: 3055 TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS 3104



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 184/886 (20%), Positives = 292/886 (32%), Gaps = 135/886 (15%)

Query: 49   PLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLT 108
            P+ T L A S+    + T   + T  +T   A SS  +S G          P S+  + T
Sbjct: 1343 PVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEG-------TSMPNSNPSEGT 1395

Query: 109  LSYSKTVSEDRPQAVSSGHTRCEKAADTA-PGQTLAPRGGSPRSQ------ASRPRRRKI 161
               +       P   S   T      DT+ PG T A    SP +        S P   K 
Sbjct: 1396 TPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKT 1455

Query: 162  PLLPSRRGEPLMMPPPLELG---YRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSR 218
            PL    +  P+   P           T  D +     +    +S    E  +I+   PS 
Sbjct: 1456 PL----KSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSE 1511

Query: 219  PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQ 278
             S  L+S+        PVS      ++            +  L++   V+ST PV+   Q
Sbjct: 1512 GSTALTSI--------PVSTTTVASSE------------INSLSTTPAVTST-PVTTYSQ 1550

Query: 279  RPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRT-----RSAPAAAAA 333
                P  +    +  TS++S  S  +TS+  +     S +A    T     ++   A+  
Sbjct: 1551 ASSSPTTADGTSMQ-TSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTE 1609

Query: 334  APPPSTLNPTSGSLLNAVDGGP--SHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRN 391
            A   +T   +S ++    +G P  +    S T  A  + S +     + +      +   
Sbjct: 1610 ASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTL---STTPVDSNSPVITST 1666

Query: 392  ASSSSHSSTEG--------------LPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSS 437
              SSS +  EG              L  +  R  P +S    A S+  T   D    V++
Sbjct: 1667 EVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASS---AISTLSTTPVDNSTPVTT 1723

Query: 438  GHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLA 497
              T       T+ G ++     S  S+ + P   +++ V    +     S  S T    +
Sbjct: 1724 S-TEARSSPTTSEGTSMP---NSTPSEGTTPL--TSIPVSTTPVLSSEASTLSATPIDTS 1777

Query: 498  TGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASA-----------AELPSTAPVSGK 546
            T  +     + +PT       P S    G+  PL S            A   ST PV   
Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTLSEGM-TPLTSTPVSHTLVANSEASTLSTTPVDSN 1836

Query: 547  KHRPPGPLFSSSDPLPA------TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPG-TS 599
                     SSS P PA      TS+ S  S  +TS+  +  T AS +     T P  TS
Sbjct: 1837 SPVVTSTAVSSS-PTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTS 1895

Query: 600  APAA--AAAAPPPSTLN--------------PTSGSLLNAVDEGPSHFLASATAAARARR 643
             P    A  +  P+T +              P +   ++      S     +T  A  R 
Sbjct: 1896 TPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRT 1955

Query: 644  SQVRYNQRSQTSRTRSCLKRNASSSSHSSTE------GLQELKRRRGPASSHCQLALSSS 697
                Y+Q S +  T         + S  ST           +        S   +  S+ 
Sbjct: 1956 PVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTP 2015

Query: 698  NTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCR 757
             T S +G  + ++      +  T P +   P  G P S  +   ++S  +       D +
Sbjct: 2016 ATTSTEGSSSPTTAGGTSIQTST-PSERTTPLAGMPVS--TTLVVSSEGNTLSTTPVDSK 2072

Query: 758  PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLAS-AAEVSSTAPVS 816
                + T +S +  A G      AP+    +  P          P+AS  A   ST PV 
Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPS----EGSPLLTSIPLSTTPVASPEASTLSTTPVD 2128

Query: 817  GKKHRPPGPLFS----SSDPLPATSSHSGDSAQDTSLIPAPFTPAS 858
                    P+ +    SS P+P   +    S       P    P S
Sbjct: 2129 SN-----SPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVS 2169



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 163/862 (18%), Positives = 273/862 (31%), Gaps = 111/862 (12%)

Query: 81   ISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQ 140
            +++S  ++      K    P S+  +++ S +  +    P A S   T      DT   +
Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDT---R 2661

Query: 141  TLAPRGGSPRSQASRPRRRKIPL-LPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQR 199
            TL        S  +      +P   P  R  PL           V+   L   + +    
Sbjct: 2662 TLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLT-------NILVSTTLLANSEASTLST 2714

Query: 200  --INSALHVEDKAISDCRPSRPSHTLSSLATGASGGPP-----VSKAPTMDAQQDRPKSQ 252
              ++++  V   A +   P+    T   ++T + G  P     VS  P   ++     S 
Sbjct: 2715 TPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTV-ST 2773

Query: 253  DCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPL--------------------- 291
              +    P+ ++ E SS+   +     P      +S PL                     
Sbjct: 2774 TAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTT 2833

Query: 292  ------PATSSHSRDSAQVTSM-IPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPT- 343
                  P T+S    S+  T+  I  P + AS  + +  +        A+   STL+ T 
Sbjct: 2834 PVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893

Query: 344  ---SGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSST 400
               S  +  + +G  S   A  T+   +  SEV     S +  T       AS+ S +  
Sbjct: 2894 VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV 2953

Query: 401  EGLPELKRRRGPASSHCQLAHSSSKTVSEDG--------------PQAVSSGHTRCEKRA 446
            +    +      ASS    A  +S  +S  G              P A S   T     A
Sbjct: 2954 DTRTPVTTS-AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPA 3012

Query: 447  DTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506
            DT+   T +    S  + A    I  +   E        P   +      A+  S  P  
Sbjct: 3013 DTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD 3072

Query: 507  SKAPTMDAQQDRPKSQDCLGLLAPLASAAE---------------------------LPS 539
            S +P + + +         G   P+++ +E                           + +
Sbjct: 3073 SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT 3132

Query: 540  TAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSM-IPAPFTAASRDAGMRRTRPGT 598
            + PV+        P  S    +P TS+ S  S  +T M +      +S D+ +  T   T
Sbjct: 3133 STPVTTSTEAHSSPTTSEGTSMP-TSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDT 3191

Query: 599  SAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTR 658
            S P   +     ST    +    +   EG +   +   +      S+      +      
Sbjct: 3192 STPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNT 3251

Query: 659  SCLKRNASSSSHSSTEGLQELKRRRGPAS--------SHCQLALSSSNTVSEDGPQAVSS 710
                   +SSS  + EG           S        S   +A S ++T+S       + 
Sbjct: 3252 PLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTP 3311

Query: 711  RDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLAT 770
              T  + + + P         S  S+ S P  N +        S+   S  S T    +T
Sbjct: 3312 VTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEA--STLSTTPVDTST 3369

Query: 771  GASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSS 830
              +     S +PT       P S    G   PLAS     ST PV   +          S
Sbjct: 3370 PVTTSTEASLSPTTAEGTSIPTSSPSEG-TTPLASMP--VSTTPVVSSEVNTLSTTPVDS 3426

Query: 831  DPLPATSSHSGDS---AQDTSL 849
            + L  TS+ +  S   A+ TSL
Sbjct: 3427 NTLVTTSTEASSSPTIAEGTSL 3448



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 165/829 (19%), Positives = 287/829 (34%), Gaps = 124/829 (14%)

Query: 10   VQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPG--PLQTDLHAQSSEIRYNQTS 67
            +   P D  T P  T    S+     +  G+    P  G  PL T +   ++ +   + S
Sbjct: 3007 LSRTPADTST-PVTTSTEASSSPTTAEGTGIPISTPSEGSTPL-TSIPVSTTPVAIPEAS 3064

Query: 68   QTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSYSKTVSEDRPQAVSSGH 127
              S T   +    ++S+  S+   P         +S    T S   T     P + +   
Sbjct: 3065 TLSTTPVDSNSPVVTSTEVSSSPTPA------EGTSMPISTYSEGSTPLTGVPVSTTPVT 3118

Query: 128  TRCEKAADTAPGQTLAPRGGSPRSQASRPRRR--KIPLLPSRRGEPLMMPPPLELGYRVT 185
            +       T P  T  P   S  + +S        +P      G   +   P+     V+
Sbjct: 3119 SSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVS 3178

Query: 186  AEDLHLEKQ--------AAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVS 237
            +ED  L                  S+   E  +I    PS     L+S+        PVS
Sbjct: 3179 SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSV--------PVS 3230

Query: 238  KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSH 297
              P   ++             A + S   V S  P++   +    P  +    +P TS+ 
Sbjct: 3231 NTPVASSE-------------ASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMP-TSTP 3276

Query: 298  SRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSH 357
            S  S  +TSM  +  T AS +     T  A  +     P +T +  S S        P  
Sbjct: 3277 SEGSTPLTSMPVSTTTVASSETSTLSTTPADTST----PVTTYSQASSS--------PP- 3323

Query: 358  FLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHC 417
             +A  T+   +  SE      +    T   +   AS+ S +             P  +  
Sbjct: 3324 -IADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT-------------PVDTST 3369

Query: 418  QLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVE 477
             +  S+  ++S    +  S           ++P +   P    P S  + P ++S ++  
Sbjct: 3370 PVTTSTEASLSPTTAEGTSI--------PTSSPSEGTTPLASMPVS--TTPVVSSEVNTL 3419

Query: 478  DKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMD----AQQDRPKSQDCLGLLAPLAS 533
                 D      S+TL + +T AS  P +++  ++     ++   P S   L      +S
Sbjct: 3420 STTPVD------SNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASS 3473

Query: 534  AAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRR 593
             A   ST PV         P+ +SS   P  SS +  +A+VTSM   P + A   +    
Sbjct: 3474 EASTLSTTPVDTST-----PVTTSS---PTNSSPT--TAEVTSM---PTSTAGEGSTPLT 3520

Query: 594  TRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQ 653
              P ++ P A++ A   ST    S + + +  +      +S+ A  +    ++       
Sbjct: 3521 NMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQA-----SSSPATLQVTTMRMSTPSEGS 3575

Query: 654  TSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSN----TVSEDGPQAVS 709
            +S T   L     +SS +ST     + R   P ++  Q   + +     T+    P  VS
Sbjct: 3576 SSLTTMLLSSTYVTSSEASTPSTPSVDRST-PVTTSTQSNSTPTPPEVITLPMSTPSEVS 3634

Query: 710  SRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLA 769
            +  T    + T+   T++  G      AS   ++++  V         P  P  T   + 
Sbjct: 3635 TPLTIMPVSTTS--VTISEAG-----TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIW 3687

Query: 770  TGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAP--LASAAEVSSTAPVS 816
            T + G  P++   TM     R  S +   L  P  + S    +ST  +S
Sbjct: 3688 TPSEGSTPLT---TMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAIS 3733



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 101/466 (21%), Positives = 172/466 (36%), Gaps = 40/466 (8%)

Query: 260  PLASAAEVSSTAPVSGKKQRPPG---PLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAAS 316
            P+ ++  V ++  VS     P G   P+++ S+     ++    + +VTS   +  +  S
Sbjct: 3659 PVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPS 3718

Query: 317  RDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYN 376
                   T S  A +++A   ST    S  +  +  G  +  L S T   R   S     
Sbjct: 3719 VVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLG--TTILVSTTPVTRFPESSTP-- 3774

Query: 377  QRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVS 436
                +  + S    +  SSS ++ EG   +     P S+  +   S+  T     P +V 
Sbjct: 3775 SIPSVYTSMSMTTASEGSSSPTTLEGTTTM-----PMSTTSE--RSTLLTTVLISPISVM 3827

Query: 437  SGHTRCEKRADTAPGQTLAPRGGSPRSQA-SRPHINSALHVEDKAISDCRPSRPSHTL-- 493
            S          T PG T  P   S ++ + S P   + + +   +I+  R S P  TL  
Sbjct: 3828 SPSEA--STLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRI---SITSER-STPLTTLLV 3881

Query: 494  SSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGL----LAPLASAAELPSTAPVSGKKHR 549
            S+    +  G  ++  P +D       S D        +A   S + +   +        
Sbjct: 3882 STTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFI 3941

Query: 550  PPGPLFSSS-DPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAP 608
            P  P+ SS+ D  PAT+         ++ +  P T++S       T    + PA   AAP
Sbjct: 3942 PSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAP 4001

Query: 609  PPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSS 668
                   T+ S       G        T+A+    +   +   S T+R  +     +S S
Sbjct: 4002 LTYVTMSTAPSTPRTTSRG------CTTSASTLSATSTPHTSTSVTTRPVT----PSSES 4051

Query: 669  SHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTR 714
            S  ST     +     PA S      S+S+T     P+AV++  TR
Sbjct: 4052 SRPSTITSHTIPPTFPPAHSSTPPTTSASSTTV--NPEAVTTMTTR 4095


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 160/694 (23%), Positives = 233/694 (33%), Gaps = 107/694 (15%)

Query: 116  SEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRS---QASRPRRRKIPLLPSRRGEPL 172
            S++  +AV S H    K A   P   L+P   SP S     S       P  P+RR    
Sbjct: 647  SDEDERAVGSLHP---KGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARR---- 699

Query: 173  MMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASG 232
                        T      E+ ++     S L       S   P++P H  S L+ G   
Sbjct: 700  ------------TPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQP-HLSSPLSKGGKD 746

Query: 233  GPPV----SKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSS 288
            G       S AP+         S         L+S  +VS  A  S  +    G      
Sbjct: 747  GEDAPATNSNAPSRSTMSSSVSSH--------LSSRTQVSEGAEASDGESHGDGDREDGG 798

Query: 289  DPLPATSSHSRD---SAQVTSMIPAPFTAASRDAGM----RRTRSAPAAAAAAPPPSTLN 341
                AT+   R    S     +   PF A  R        R  R  P+++  +  PS  +
Sbjct: 799  RQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAH 858

Query: 342  PTSGS-------LLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNAS- 393
            P   S       L + + G            A      V  + R  ISR    L+R+   
Sbjct: 859  PRVPSHSDSHPKLSSGIHGDEED---EKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQR 915

Query: 394  SSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQT 453
             +S    E +PE  +  G A +H Q  +SS  + ++D  Q+           ADT     
Sbjct: 916  GASLHRKEPIPENPKSTG-ADTHPQGKYSSLASKAQDVQQSTD---------ADT----- 960

Query: 454  LAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMD 513
                G SP++Q      +++      A S   PS P       A      PPV+ +    
Sbjct: 961  ---EGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHP 1017

Query: 514  AQQDRPKSQDCLGLLAPLASAAELPSTAPVS-GKKHRPPGPLFSSSDPLPATSSHSRDSA 572
              Q R   +       P  S  +     P S G+ H    P  +SS  +  T+  ++D  
Sbjct: 1018 GPQSRDAGRSPS---QPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDED 1074

Query: 573  QVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFL 632
               S         ++D  +R       A  AAA+ P    +   +G+       G  H  
Sbjct: 1075 AQGSYDDDSTEVEAQD--VRAPAHAARAKEAAASLPKHQQVESPTGA-----GAGGDHRS 1127

Query: 633  ASATAAARAR-------RSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGP 685
                AA+ AR       +S+ R   R+   ++    KR  SS S  S     + +   G 
Sbjct: 1128 QRGHAASPARPSRPGGPQSRARVPSRAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGF 1187

Query: 686  ASSHCQLALSSS--NTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGS--------PRS 735
                 +  LSSS     S   P+     D    K +  P   LAPRGGS        P  
Sbjct: 1188 FKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLPPP 1247

Query: 736  QASRPRINSALHVEDKAISDCRPSRPSHTLSSLA 769
              S PR   A HV  +      P R + T+S +A
Sbjct: 1248 PGSSPR---ASHVPSRL-----PPRSAATVSPVA 1273



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 166/767 (21%), Positives = 260/767 (33%), Gaps = 132/767 (17%)

Query: 140  QTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQR 199
            + L  R  SP S +    +++    PSR G  ++ P    +  R+ A    L ++    +
Sbjct: 544  EELGSREDSPMSPSDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPA----LPRREGVDK 599

Query: 200  INSALHVEDK-AISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLV 258
               +L  + +        + P+H  S+   G S  P +  +   +   D  + +  +G +
Sbjct: 600  PGFSLATQPRPGAPPSASASPAHHAST--QGTSHRPSLPASLNDNDLVDSDEDERAVGSL 657

Query: 259  APLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRD 318
             P  + A+              P P  S S   P++    R S    +   +P       
Sbjct: 658  HPKGAFAQ--------------PRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHS 703

Query: 319  AGMRRTRSAPAAAAAAPPP----STLNPTSGSLLNAVD-GGPSHFLASATAAARAQRSEV 373
                   SA A  +   PP    S L PT   L + +  GG     A AT +    RS +
Sbjct: 704  GAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTM 763

Query: 374  RYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRG----------PASSHCQLAHSS 423
              +  S +S      +   +S   S  +G  E   R+           PAS H  L    
Sbjct: 764  SSSVSSHLSSRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHK 823

Query: 424  SKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQA---SRPHINSALHVEDK- 479
                +   P   S G  R  +   ++  Q+  P    PR  +   S P ++S +H +++ 
Sbjct: 824  PFAANGRSPSRFSIG--RGPRLQPSSSPQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEED 881

Query: 480  -------AISDCRPSRPSHTLS--------SLATGAS--RGPPVSKAPTMDAQQDRPKSQ 522
                    ++D  PS     +S        S   GAS  R  P+ + P        P+  
Sbjct: 882  EKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPQ-- 939

Query: 523  DCLGLLAPLASAAE-LPSTAPVSGKKHRP---PGPLFSSSDPLPATSSHSRDSAQVTSMI 578
               G  + LAS A+ +  +     + H P   PG     + P    ++ S+    V    
Sbjct: 940  ---GKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVP--- 993

Query: 579  PAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAA 638
                         RR  PG +        PP +T     G         PS    S T A
Sbjct: 994  -------------RRMTPGRAPQQQPP--PPVATSQHHPGPQSRDAGRSPSQPRLSLTQA 1038

Query: 639  ARAR-RSQVRYNQRSQ--TSRTR----SCLKRNASSSSHSSTEGLQELKRRRGPASSHCQ 691
             R R  SQ R +  S   T+ +R    + L+     +  S  +   E++ +   A +H  
Sbjct: 1039 GRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQDVRAPAHAA 1098

Query: 692  LALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDK 751
             A  ++ ++ +   Q V S              T A  GG  RSQ               
Sbjct: 1099 RAKEAAASLPKH--QQVES-------------PTGAGAGGDHRSQRGH------------ 1131

Query: 752  AISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSS 811
            A S  RPSRP    S     +   P  S+ P+      RP S      V+  A   E   
Sbjct: 1132 AASPARPSRPGGPQSRARVPSRAAPGKSEPPS-----KRPLSSKSQQSVS--AEDDEEED 1184

Query: 812  TAPVSGKKHRPPGPLFSSSDP-LPATSSHSGDSAQDTSLIPAPFTPA 857
                 G K      L SSS P  P++S+  G    D SL      PA
Sbjct: 1185 AGFFKGGKE----DLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPA 1227



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 152/689 (22%), Positives = 237/689 (34%), Gaps = 155/689 (22%)

Query: 219 PSHTLSSLATGASGGPP-VSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK 277
           P  T S+L  G   G   + K    + +   P S+  + +  P  S A+V      +GK 
Sbjct: 414 PGDTTSALVDGLQPGERYLFKIRATNRRGLGPHSKAFI-VAMPTTSKADVEQNTEDNGKP 472

Query: 278 QRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPP 337
           ++P     S S   PA+S H                            S PA+       
Sbjct: 473 EKPEPS--SPSPRAPASSQHP---------------------------SVPASPQGRNAK 503

Query: 338 STLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSH 397
             L      +L   +GG     A      RA+++E    Q ++I+       R  S  S 
Sbjct: 504 DLLLDLKNKIL--ANGG-----APRKPQLRAKKAEELDLQSTEITGEEELGSREDSPMSP 556

Query: 398 SSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADT-APGQTLA- 455
           S T+   + KR   P S H    HS    V   G  AV +      +R     PG +LA 
Sbjct: 557 SDTQ---DQKRTLRPPSRH---GHS----VVAPGRTAVRARMPALPRREGVDKPGFSLAT 606

Query: 456 -PRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDA 514
            PR G+P S ++ P    A H   +  S  RPS P+               ++    +D+
Sbjct: 607 QPRPGAPPSASASP----AHHASTQGTSH-RPSLPAS--------------LNDNDLVDS 647

Query: 515 QQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQV 574
            +D    +  +G L P  + A+              P P  S S   P++    R S   
Sbjct: 648 DED----ERAVGSLHPKGAFAQ--------------PRPALSPSRQSPSSVLRDRSSVHP 689

Query: 575 TSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFL-- 632
            +   +P          RRT    +A   ++A+ PPS L+P  G     +   P H    
Sbjct: 690 GAKPASP---------ARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQP-HLSSP 739

Query: 633 ----------ASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRR 682
                     A AT +    RS +  +  S  S      +   +S   S  +G +E   R
Sbjct: 740 LSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGESHGDGDREDGGR 799

Query: 683 RG----------PASSHCQLALSSSNTVSEDGPQAVS-SRDTRCEKADTAPGQTLAPRGG 731
           +           PAS H  L        +   P   S  R  R + + ++P  T+  R  
Sbjct: 800 QAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPS-SSPQSTVPSRAH 858

Query: 732 S--PRSQASRPRINSALHVEDK--------AISDCRPSRPSHTLS--------SLATGAS 773
              P    S P+++S +H +++         ++D  PS     +S        S   GAS
Sbjct: 859 PRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGAS 918

Query: 774 --GGPPVSKAPTMDAQQDRPKSQDCLGLVAPLAS-AAEVSSTAPVSGKKHRP---PGPLF 827
                P+ + P        P+     G  + LAS A +V  +     + H P   PG   
Sbjct: 919 LHRKEPIPENPKSTGADTHPQ-----GKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTD 973

Query: 828 SSSDPLPATSSHSGDSAQDTSLIPAPFTP 856
             + P    ++ S    Q    +P   TP
Sbjct: 974 RHASPARPPAARS----QQHPSVPRRMTP 998


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 182/902 (20%), Positives = 291/902 (32%), Gaps = 166/902 (18%)

Query: 52   TDLHAQSSEIRYNQTSQTSWTS------SSTKRNAISSSYSSTGGLPGLKQRRGPASSRC 105
            T LH+ +S   + + + TS T+      S+  R  ++ + S+T   P       P     
Sbjct: 1523 TSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRP-------PPPFTT 1575

Query: 106  QLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQAS---------RP 156
                + S   S   P   +S  T       + P QT  P    P S +           P
Sbjct: 1576 HSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHP-QTTLPTHVPPFSTSLVTPSTHTVITP 1634

Query: 157  RRRKIPLLPSRRGEPL-MMPPPLEL---GYRVTAEDLHLEKQAAFQRINSALHVEDKAIS 212
               ++    S    P   +PPP  L   G   TA  + L      Q ++S    +     
Sbjct: 1635 THAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTST-- 1692

Query: 213  DCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAP 272
                S  SHT S+    A+     +  P   +    P +    G     +S +   ++  
Sbjct: 1693 ----SLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTS 1748

Query: 273  VSGKKQRPPGPLFSSSDPLPATSSHS---------RDSAQVTSMIPAPFTAASRDAGMRR 323
            +         P  +S+     T +H+           ++  +S +P PFT  S   G   
Sbjct: 1749 LHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTP 1808

Query: 324  TRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISR 383
              S     A +   +T  PT       +   P+H  + +T+        V     +Q++ 
Sbjct: 1809 ISSTGPVTATSFQTTTTYPTPSHPHTTL---PTHVPSFSTSLVTPSTHTVIIPTHTQMA- 1864

Query: 384  TRSCLKRNASSSSHSSTEG-LPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRC 442
                     S+S HS   G +P     +   S+H     + + + +   P + S+  T  
Sbjct: 1865 --------TSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT-- 1914

Query: 443  EKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASR 502
                                   S P+  S+ H  +   +      P HT +   T  + 
Sbjct: 1915 ---------------------STSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAH 1953

Query: 503  GPPVSKA--PTMDAQQDRPKSQDCLGLLAPLASAA-------ELPSTAPVSGKKHRPPGP 553
                S +  PT       P          P+ + +         PS    +   H PP  
Sbjct: 1954 TTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPP-- 2011

Query: 554  LFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTL 613
             FS+S   P+T +          +I    T  +  A +  T  GT         PPP+TL
Sbjct: 2012 -FSTSLVTPSTHT----------VIITTHTQMATSASIHSTPTGT--------VPPPTTL 2052

Query: 614  NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSS- 672
              T GS   A    P     S T+   +  S    +  S    + S L +N+SS   SS 
Sbjct: 2053 KAT-GSTHTAP---PMTVTTSGTSQTHSSFSTATAS--SSFISSSSWLPQNSSSRPPSSP 2106

Query: 673  -TEGLQELKRRRGPASSHCQLALSSS------NTVSEDGPQAVSSRDTRCEKADTAPGQT 725
             T  L  L     P S+  QL+ S S      +TVS   P + SS  T      T+    
Sbjct: 2107 ITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFV 2166

Query: 726  LAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPS----------HTLSS-------- 767
             AP   +  S  S   +++       + S   PS P+          HT+SS        
Sbjct: 2167 SAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALL 2226

Query: 768  --------------LATGASGGPPVSK-------APTMDAQQDRPKSQDCLGLV-----A 801
                          LA+     P   +       AP   +Q    +S      V      
Sbjct: 2227 PISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286

Query: 802  PLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPASRDA 861
             L S      T+PV+    R PGP  S +     +S  +  S   ++ + +  TP     
Sbjct: 2287 SLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSP 2346

Query: 862  GV 863
            GV
Sbjct: 2347 GV 2348



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 140/666 (21%), Positives = 234/666 (35%), Gaps = 111/666 (16%)

Query: 216  PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSG 275
            P  P+   SS  T +SG PP    PT       P++   L   A L S A   +    + 
Sbjct: 1253 PLLPATLTSSKPTASSGEPP---RPTTAVT---PQATSGLPPTATLRSTATKPTVTQATT 1306

Query: 276  KKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAP 335
            +         ++S   PAT+S ++ + + T  +P P T+ +       + + P +     
Sbjct: 1307 RA--------TASTASPATTSTAQSTTRTTMTLPTPATSGT-------SPTLPKSTNQEL 1351

Query: 336  PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSS 395
            P +T   T+         GP    AS T     Q  +      ++ ++TR+  +     +
Sbjct: 1352 PGTTATQTT---------GPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQT 1402

Query: 396  SHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTL- 454
             H +T   P                 ++   V   GP   +S H        + P  TL 
Sbjct: 1403 PH-TTHSPP-----------------TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444

Query: 455  --APRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTL----SSLATGASR-GPPVS 507
               P   +     S   + +  H +  A S    S P+ T+    +  ATG++   PP++
Sbjct: 1445 THVPPFSTSLVTPSTHTVITPTHAQ-MATSASNHSAPTGTIPPPTTLKATGSTHTAPPIT 1503

Query: 508  KAPTMDAQQDRPKSQDCLGL-LAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSS 566
               +  +Q     S +     L    S+   P   P S     P      +  P+  T+S
Sbjct: 1504 PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNS 1563

Query: 567  HSRDSAQVTSMIPAPFTAASRDAG---MRRTRPGTSAPAAAAAAPP----PSTLNPTSGS 619
                    +S  P PFT  S   G      T P T+         P    P T  PT   
Sbjct: 1564 ------ATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVP 1617

Query: 620  LLNAVDEGPS-HFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHS------S 672
              +     PS H + + T A  A  + + ++  + T    + LK  A+ S+H+      +
Sbjct: 1618 PFSTSLVTPSTHTVITPTHAQMATSASI-HSMPTGTIPPPTTLK--ATGSTHTAPTMTLT 1674

Query: 673  TEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGS 732
            T G  +       A +   L   +S+T   +     ++  T    +   P  T+   G S
Sbjct: 1675 TSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTS 1734

Query: 733  -PRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRP 791
              RS  S  + +++LH              SHT S      +  P V+   T     +  
Sbjct: 1735 QSRSSFSTAKTSTSLH--------------SHTSS------THHPEVTSTSTTSITPNHT 1774

Query: 792  KSQDCLGLVAPLA-SAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLI 850
             +    G   P+A + +  SS  P     H PP    + + P+ +T   +  S Q T+  
Sbjct: 1775 ST----GTRTPVAHTTSATSSRLPTPFTTHSPP----TGTTPISSTGPVTATSFQTTTTY 1826

Query: 851  PAPFTP 856
            P P  P
Sbjct: 1827 PTPSHP 1832



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 85/394 (21%), Positives = 127/394 (32%), Gaps = 46/394 (11%)

Query: 482  SDCRPSRPSHTLSSLATGASRGPPVSKA-PTMDAQQDRPKSQDCLGLLAPLASAAELPST 540
            S+  P+ P+ T    AT  S  P  S   P        P++   L   A L S A  P+ 
Sbjct: 1242 SNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTV 1301

Query: 541  APVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTR---PG 597
               + +         ++S   PAT+S ++ + + T  +P P T+ +     + T    PG
Sbjct: 1302 TQATTRA--------TASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPG 1353

Query: 598  TSAPAAAAAAP-PPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSR 656
            T+A       P P ST  PT+          P              R+   Y        
Sbjct: 1354 TTATQTTGPRPTPASTTGPTTPQ--------PGQPTRPTATETTQTRTTTEYTTPQTPHT 1405

Query: 657  TRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLAL--------------SSSNTVSE 702
            T S     +   S               P  SH +  L              S+   ++ 
Sbjct: 1406 THSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITP 1465

Query: 703  DGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPS 762
               Q  +S         T P  T     GS     + P I        +A S    ++  
Sbjct: 1466 THAQMATSASNHSAPTGTIPPPTTLKATGSTH---TAPPITPTTSGTSQAHSSFSTNKTP 1522

Query: 763  HTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRP 822
             +L S  T ++  P V+   T     + P S      VA   SA   SS  P     H P
Sbjct: 1523 TSLHS-HTSSTHHPEVTPTSTTTITPN-PTSTRTRTPVAHTNSA--TSSRPPPPFTTHSP 1578

Query: 823  PGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTP 856
            P    + S P  +T   +  S + T+  P P  P
Sbjct: 1579 P----TGSSPFSSTGPMTATSFKTTTTYPTPSHP 1608



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 139/639 (21%), Positives = 216/639 (33%), Gaps = 128/639 (20%)

Query: 52   TDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPASSRCQLTLSY 111
            T LH+ +S   + + + TS TS       I+ +++STG    +       SSR     + 
Sbjct: 1747 TSLHSHTSSTHHPEVTSTSTTS-------ITPNHTSTGTRTPVAHTTSATSSRLPTPFTT 1799

Query: 112  ------SKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLP 165
                  +  +S   P   +S  T       + P  TL     S  +    P    + ++P
Sbjct: 1800 HSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV-IIP 1858

Query: 166  SRRGEPLM----------MPPPLEL---GYRVTAEDLHLEKQAAFQRINSALHVEDKAIS 212
            +                 +PPP  +   G   TA  +        Q  +S       + +
Sbjct: 1859 THTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSF------STA 1912

Query: 213  DCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTA- 271
                S P HT S+        P V+   T +       +    G   P+A     SS+  
Sbjct: 1913 KTSTSLPYHTSST------HHPEVTPTSTTNITPKHTST----GTRTPVAHTTSASSSRL 1962

Query: 272  PVSGKKQRPP--GPLFSSSDPLPATS--------SHSRDSAQVTSMIPAPFTAA----SR 317
            P       PP     FSS+ P+ ATS        + S     + + +P PF+ +    S 
Sbjct: 1963 PTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVP-PFSTSLVTPST 2021

Query: 318  DAGMRRTRSAPAAAAA--------APPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQ 369
               +  T +  A +A+         PPP+TL  T GS   A    P     S T+   + 
Sbjct: 2022 HTVIITTHTQMATSASIHSTPTGTVPPPTTLKAT-GSTHTAP---PMTVTTSGTSQTHSS 2077

Query: 370  RSEVRYNQRSQISRTRSCLKRNASSSSHSS--TEGLPELKRRRGPASSHCQLAHSSS--- 424
             S    +  S    + S L +N+SS   SS  T  LP L     P S+  QL+ S S   
Sbjct: 2078 FSTATAS--SSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSP 2135

Query: 425  ---KTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAI 481
                TVS   P + SS  T       T+     AP   +  S  S   +++       + 
Sbjct: 2136 SAPSTVSSYVPSSHSSPQTSSPS-VGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA 2194

Query: 482  SDCRPSRPS----------HTLSS----------------------LATGASRGPPVSK- 508
            S   PS P+          HT+SS                      LA+     P   + 
Sbjct: 2195 SPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRT 2254

Query: 509  ------APTMDAQQDRPKSQDCLGLLAPLASAAELPS------TAPVSGKKHRPPGPLFS 556
                  AP   +Q    +S   L    P +    L S      T+PV+    R PGP  S
Sbjct: 2255 TASTHTAPAFSSQSTTSRSTS-LTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLS 2313

Query: 557  SSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTR 595
             +     +S  +  S   ++ + +  T      G+   R
Sbjct: 2314 PTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVR 2352



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 52/225 (23%), Positives = 81/225 (36%), Gaps = 26/225 (11%)

Query: 554  LFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGM-RRTRPGTS-APAAAAAAPPPS 611
            L SS+ P P+ S+H+  S   T ++PA  T++   A      RP T+  P A +  PP +
Sbjct: 1232 LLSSTGPSPS-SNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTA 1290

Query: 612  TLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHS 671
            TL  T+      V +  +   AS  + A    +Q        T+RT   L   A+S +  
Sbjct: 1291 TLRSTATK--PTVTQATTRATASTASPATTSTAQ-------STTRTTMTLPTPATSGTSP 1341

Query: 672  S-----------TEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADT 720
            +           T   Q    R  PAS+                 +   +R T       
Sbjct: 1342 TLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQ 1401

Query: 721  APGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTL 765
             P  T +P        ++ P   ++ H      +   PS P  TL
Sbjct: 1402 TPHTTHSPPTAGSPVPSTGPVTATSFHA---TTTYPTPSHPETTL 1443



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 72/322 (22%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 44   VPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGG------------- 90
            VP P  L+      ++      TS TS T SS      SSS+ S+               
Sbjct: 2046 VPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSS 2105

Query: 91   -----LPGLKQRRGPASSRCQLTLSYS------KTVSEDRPQAVSSGHTRCEKAADT--- 136
                 LP L     P S+  QL+ S+S       TVS   P + SS  T       +   
Sbjct: 2106 PITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSF 2165

Query: 137  --APGQTLAPRGGSPRSQASRPRRRKI---PLLPSRRGEPLMMPPPLELGYRVTAEDLHL 191
              AP  +     GS  S ++ P    +   PL PS         P      R T   L  
Sbjct: 2166 VSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSS--------PAASTTIRAT---LPH 2214

Query: 192  EKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKS 251
               + F  +++ L +    +S   P+  SH  SS     S     +   T  A   +  +
Sbjct: 2215 TISSPFT-LSALLPISTVTVS---PTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTT 2270

Query: 252  QDCLGLVAPLASAAEVS--------STAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQ 303
                 L   + ++  VS         T+PV+    R PGP  S +     +S  +  S  
Sbjct: 2271 SRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTP 2330

Query: 304  VTSMIPAPFTAASRDAGMRRTR 325
             ++ + +  T      G+   R
Sbjct: 2331 ASAPVSSLGTPTPTSPGVCSVR 2352


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 123/533 (23%), Positives = 173/533 (32%), Gaps = 76/533 (14%)

Query: 114 TVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLM 173
           T+ E  P+A   G TR    +   P       G   R+  ++      P+    R     
Sbjct: 69  TIPESAPRA---GPTRSAGTSSRNPASRPPASGRGERAPPAK-NTSPGPVSSPGRASGTT 124

Query: 174 MPPPL-ELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASG 232
            P PL + G R++AE+     +A      SAL                   +      SG
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALS------------------AGARRDTSG 166

Query: 233 GPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLP 292
             P + +P M A++ R             A+  EV    P    + RPP     +  P  
Sbjct: 167 PTPGTPSPAM-ARRSR-------------AAGTEVGLPRPAPSARPRPP-----TEGPRK 207

Query: 293 ATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVD 352
           + SS S  S   T   PA     S   G++R  S   +++A P  S     SG       
Sbjct: 208 SVSSASEHST--TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR--SGPSARGTP 263

Query: 353 GGPSHFLASATAAARAQR----SEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKR 408
             P+H         +A R    +  R +    +    S      S S+   ++  P L  
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323

Query: 409 RRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRP 468
               +S  CQLA  +   ++   P A  S  T     A T P Q     G SP  QA+  
Sbjct: 324 TPHSSSLTCQLA--TPLPLAPPSPSAPPSLQTLPSPPA-TPPSQATTSLG-SPTLQATHS 379

Query: 469 HINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLL 528
            +                  PS  LS LAT   + PP    P + A    P S     L 
Sbjct: 380 FL------------------PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421

Query: 529 APLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRD 588
            P   A    +   +      PP P   +    PA+   S  SA   S  P    A    
Sbjct: 422 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQ 480

Query: 589 AGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARA 641
                  P  S P + +A PPP    P +   L      P    A AT   +A
Sbjct: 481 VP---PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 104/463 (22%), Positives = 157/463 (33%), Gaps = 64/463 (13%)

Query: 403 LPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPR 462
           +PE   R GP  S    A +SS+  +   P   S    R     +T+PG   +P   S  
Sbjct: 70  IPESAPRAGPTRS----AGTSSRNPASRPP--ASGRGERAPPAKNTSPGPVSSPGRASGT 123

Query: 463 SQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASR---GP-PVSKAPTMDAQQDR 518
           ++   P     L +  +       +  +   S+L+ GA R   GP P + +P M A++ R
Sbjct: 124 TRPG-PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM-ARRSR 181

Query: 519 PKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMI 578
                        A+  E+    P    + RPP     +  P  + SS S  S       
Sbjct: 182 -------------AAGTEVGLPRPAPSARPRPP-----TEGPRKSVSSASEHSTTE---- 219

Query: 579 PAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAA 638
           P+P       AG    RP + + +++A    P +    SG         P+H        
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSAT---PLSSPARSGPSARGTPRAPAHPSQPKPKG 276

Query: 639 ARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSH-----CQLA 693
            +A R       R   +     L  ++  ++ S +  LQ       PA+ H     CQLA
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLS-SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335

Query: 694 LSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAI 753
             +   ++   P A  S  T      T P Q     G SP  QA+   +           
Sbjct: 336 --TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG-SPTLQATHSFL----------- 381

Query: 754 SDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTA 813
                  PS  LS LAT     PP    P + A    P S     L  P   A    +  
Sbjct: 382 -------PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434

Query: 814 PVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTP 856
            +      PP P   +    PA+   S  +   +   P+   P
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 111/531 (20%), Positives = 173/531 (32%), Gaps = 73/531 (13%)

Query: 101 ASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRK 160
           A  R  L+    +  S   P   S    R  +AA T  G         PR     PR+  
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS- 208

Query: 161 IPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPS 220
              + S        P P     R  +    L++ A+    +SA  +   A      S PS
Sbjct: 209 ---VSSASEHSTTEPSP--AARRRPSAGGGLQRPASRSLSSSATPLSSPA-----RSGPS 258

Query: 221 HTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRP 280
              +  A      P       +   Q  P  +D    + PL+S+   + +   + + Q P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318

Query: 281 PGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTL 340
           P         LPAT   S  + Q+ + +P    + S    ++   S PA   +    S  
Sbjct: 319 P--------TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370

Query: 341 NPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSST 400
           +PT  +  + +   P   LA+    A                                  
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQA-------------------------------PPA 399

Query: 401 EGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAP--GQTLAPRG 458
             LP L   + P S       S   T S   P A++    +       +P      +P  
Sbjct: 400 LALPPL---QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456

Query: 459 GSPRSQASRPHINSALHVEDKAISDCRPSRP-SHTLSSLATGASRGPPVSKAPTMDAQQD 517
             P S ++ P   +   +    +    PS P S  +S  AT   + PP   AP +   + 
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPL-QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515

Query: 518 RPKSQDCLG---LLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQV 574
            P++   L    L A  +  A  P  AP S     P  PL +     P        +A +
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL-----AAPL 570

Query: 575 TSMIPAPFTAASRDAGMRRTRPG----TSAP----AAAAAAPPPSTLNPTS 617
             + P+P  + +  A  R   PG     S P    A A   PPP + +P+S
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 135/590 (22%), Positives = 199/590 (33%), Gaps = 80/590 (13%)

Query: 46  RPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSY--SSTGGLPGLKQRRGPASS 103
           RPGPL      +   I   +T      + + KR+A+S+     ++G  PG         S
Sbjct: 125 RPGPLGQ----KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180

Query: 104 RCQLT-LSYSKTVSEDRPQAVSSGHTRCEKAAD---TAPGQTLAPRGGSPRSQASRPRRR 159
           R   T +   +     RP+  + G  +   +A    T      A R  S      RP  R
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 160 KIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRP 219
            +    +    P    P      R  A      K    Q +        +   D  P+  
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPR--KDAAPALG 297

Query: 220 SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQR 279
             + S LAT +      S+AP          S  C  L  PL  A    S  P       
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ-LATPLPLAPPSPSAPPSLQTLPS 356

Query: 280 PPGPLFSSSDPLPATSSHSRDSAQVT-SMIPAPFTAA-------SRDAGMRRTRSAPAAA 331
           PP     ++ P  AT+S    + Q T S +P+P  +        +  A       AP + 
Sbjct: 357 PP-----ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 411

Query: 332 AAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRN 391
            A+PP S L   S    NA+     H L +  +   +   +  ++  +    + S    +
Sbjct: 412 PASPPLSPLATPSPQAPNAL---AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468

Query: 392 ASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPG 451
            +  S ++    P L+    P +S      S S T     P  +++            P 
Sbjct: 469 QAPPSLAA----PPLQVPPSPPASPPM---SPSATPPPQAPPPLAA-----------PPL 510

Query: 452 QTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTL--SSLATGASRGPPVSKA 509
           Q   P   +P + A+ P    AL     +     P  PS +L  S LAT   + PPV  A
Sbjct: 511 QLAKPPPQAPPALATPPL--QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568

Query: 510 PTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKK-------HRPPGPLFSSSDPL- 561
           P +      P S     L AP       P T+ VSG +         PP P  S S  L 
Sbjct: 569 PLLQVPPSPPASPT---LQAPRRPPTPGPDTS-VSGPRLTLALAPGPPPPPSRSPSSTLS 624

Query: 562 -PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPP 610
            P  + HS      +S    P      D+G             AAA+PPP
Sbjct: 625 GPDLAGHS------SSATSTPEELRGYDSG---------PEGGAAASPPP 659



 Score = 37.7 bits (86), Expect = 0.048
 Identities = 96/416 (23%), Positives = 128/416 (30%), Gaps = 55/416 (13%)

Query: 42  PFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGPA 101
           P  P+P  LQ     Q +  R +        SSS       S+   +   P L      +
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSS 328

Query: 102 SSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKI 161
           S  CQL       ++   P A  S  T     A T P Q     G SP  QA+       
Sbjct: 329 SLTCQLATPLP--LAPPSPSAPPSLQTLPSPPA-TPPSQATTSLG-SPTLQATHSFLPSP 384

Query: 162 PLLPSRRGEPLMMP----PPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPS 217
           PL P     P   P    PPL+      A            +  +AL V         P 
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444

Query: 218 RP----------SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEV 267
            P          S  +S  AT  S  PP   AP +      P S        P   A   
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504

Query: 268 SSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSA 327
            +  P+   K  P  P   ++ PL A              +P+P  +    A    + S 
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQA--------------LPSPPASFPGQAPFSPSASL 550

Query: 328 PAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSC 387
           P +  A PPP      +  LL      P      A+   +A R        + +S  R  
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPP------ASPTLQAPRRPPTPGPDTSVSGPRLT 604

Query: 388 LKRNAS-----SSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSG 438
           L          S S SST   P+L              HSSS T + +  +   SG
Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDL------------AGHSSSATSTPEELRGYDSG 648


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 160/779 (20%), Positives = 246/779 (31%), Gaps = 99/779 (12%)

Query: 120  PQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPL--MMPPP 177
            P+  S+       +   +P  T  P+G      A+ P  +  P  PS +G P      PP
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 178  LELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVS 237
               G   T          A    +    +         P+ P+ T  S   G +  PP  
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA-PTTPAATPPSPKGGLATPPPKG 1147

Query: 238  KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDP----LPA 293
               T  A    PK     GL  P    A  +  A        PP P    + P     P 
Sbjct: 1148 APTTPAATPPSPKG----GLATPPPKGAPTTPAA-------TPPSPKGGLATPSPKGAPT 1196

Query: 294  TSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDG 353
            T + +  S +     P+P             + AP   AA PP    +P  G    +  G
Sbjct: 1197 TPAATPPSPKGGLATPSP-------------KGAPTTPAATPP----SPKGGLATPSPKG 1239

Query: 354  GPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEG---LPELKRRR 410
             P+   A+  +      +       +  + T   LK   ++  H        +     + 
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299

Query: 411  GPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHI 470
            GPA+S  + A +         P    S  T   K A T P  T     G+P   A+ P  
Sbjct: 1300 GPATSPPKGAPTPPAATP---PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP-- 1354

Query: 471  NSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAP 530
             S+        S   P+ P+ T S     A   P   + P + + +  P S         
Sbjct: 1355 -SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS--------- 1404

Query: 531  LASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAG 590
                   P+  P+S KK  P  P+       P+    +  +    S+  AP T+A +   
Sbjct: 1405 -------PAVIPLSPKK-APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG- 1455

Query: 591  MRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQ 650
                 P +       A  PPS   P +   + A    P    A+           V  + 
Sbjct: 1456 --PATPSSKGDPTLPAVTPPSPKEPPAPKQV-ATSSSPKKAPATPAPMGAPTLPAVIPSS 1512

Query: 651  RSQTSRT----RSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQ 706
              +   T    R  +   A+  S  +   L   +    PA +      + +    ++ P 
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572

Query: 707  AVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLS 766
              SS++     A T      AP   SP+     P + S    E        P  P     
Sbjct: 1573 TPSSKEASSPPAVTPSTYKGAP---SPKELLIPPAVTSPSPKEAPTPPAVTPPSPE---K 1626

Query: 767  SLATGASGGPPVSKAPTMDAQQDRPKSQDC----LGLVAPLAS----------------- 805
              AT A  G P S   T  + +D P S       +G   P AS                 
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV 1686

Query: 806  AAEVSSTAPVSGKKHRPPGPLFSS--SDPL-PATSSHSGDSAQDTSLIPAPFTPASRDA 861
            A    ST  ++    + P    SS  S P+ P  S+ +G     +++ PAP  P  +D+
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 113/535 (21%), Positives = 178/535 (33%), Gaps = 60/535 (11%)

Query: 114  TVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLM 173
            T+    P +     T   K   T P  T + +GG P      P+R   P +PS +G+P  
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG-PAMTPPSPKRG--PAIPSPKGDP-T 1403

Query: 174  MPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSHTLSSLATGASGG 233
             P  + L  +         + AA              +S  +    S      AT +S G
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 234  PPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDPLPA 293
             P   A T  + ++ P  +     VA  +S  +  +T    G     P  + SS   +PA
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQ----VATSSSPKKAPATPAPMGAPTL-PAVIPSSPKEVPA 1518

Query: 294  TSSHSRDSAQVTSMI---PAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNA 350
            T S  RD    T+ +     P T A ++A +      PA    +P  +   PT       
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALI-----PPAMTVPSPKKTPAIPT------- 1566

Query: 351  VDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRR 410
                P    A+ ++   +    V  +        +  L   A +S        P      
Sbjct: 1567 ----PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622

Query: 411  GPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGS-PRSQASRPH 469
             P       A   + T     P ++        K + T+P       G + P++    P 
Sbjct: 1623 SPEKGPATPAPKGTPTSPPVTPSSL--------KDSPTSPASVTCKMGATVPQASKGLPA 1674

Query: 470  INSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLA 529
                  +++  ++    S P      + T  +R  P +K  +  +    P      G   
Sbjct: 1675 KKGPTALKEVLVAPAPESTP------IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728

Query: 530  PLASAAELP---------STAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPA 580
            PL++ A  P          TA      H P GPL     P  + +S    +A    ++P 
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL----APPESKASTPLTAAAFEKVLPK 1784

Query: 581  PFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASA 635
            P  +AS  A          AP+     PP     P+S  L   V E PS  LA A
Sbjct: 1785 P-ESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL---VLESPSKPLAPA 1835



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 98/438 (22%), Positives = 146/438 (33%), Gaps = 79/438 (18%)

Query: 220  SHTLSSLATGASGGPPVSKAPTMDAQQDRP-KSQDCLGLVAPLASAAEVSSTAPVSGKKQ 278
            SHT S+LA  AS      + PT D+       S+  L  +A   S   VS    VS + +
Sbjct: 755  SHT-SALAPVASSP---KECPTEDSGASATASSKGTLTYLADSPSPLGVS----VSPQTK 806

Query: 279  RPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTA--ASRDAGMRRTRSAPAAAAAAPP 336
            RPP    S+    P  +  S  S    S +P    +   S+D+        P +   AP 
Sbjct: 807  RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866

Query: 337  PSTLNPTSGSLLN---------AVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSC 387
            PS + P S   +          +V   P      AT A +         Q   +S T S 
Sbjct: 867  PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK---------QAPALSMTSSS 917

Query: 388  LKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRAD 447
             K+  ++ +    +G+P       P+        +++    + GP   S       K A 
Sbjct: 918  PKKARATPA---PKGIPA-----SPSPKGAPTPPAATPPSPKGGPATPSP------KWAP 963

Query: 448  TAPGQTL-APRGG----SPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASR 502
            T P  T  +P+GG    SP+   + P                  + P       AT + +
Sbjct: 964  TPPAATPPSPKGGPATPSPKGAPTPP-----------------AATPPSPKGGPATPSPK 1006

Query: 503  GPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPG-PLFSSSDPL 561
            G P   A T  + +  P +        P    A  P  A     K  P   PL   +   
Sbjct: 1007 GAPTPPAVTPPSPKGSPAA-------TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059

Query: 562  PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLL 621
            PA +  S      T  +    T  +      +  P T +P  A   P  +  +P  G   
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119

Query: 622  NAVDEGPSHFLASATAAA 639
                  P H  A  T AA
Sbjct: 1120 ------PPHKGAPTTPAA 1131


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 134/576 (23%), Positives = 190/576 (32%), Gaps = 81/576 (14%)

Query: 99  GPASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPR---GGSPRSQASR 155
           GPAS      L   +  +        S  T C   + ++PG+  +P+     SP   ++R
Sbjct: 90  GPASEEDMTKLCNHRRKAVAMATLYRSMETTC---SHSSPGEGASPQMFHTVSPGPPSAR 146

Query: 156 PRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCR 215
           P  R  P  P   G   + P P  +               AF  +     +    ++D  
Sbjct: 147 PPCRVPPTTPLNGGPGSLPPEPPSVSQ-------------AFPTLAGPGGLFPPRLADPV 193

Query: 216 PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSG 275
           PS           G S  P     P  +A    P     + L AP  +      ++ V  
Sbjct: 194 PS-----------GGSSSPRF--LPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240

Query: 276 KKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASR-DAGMRRTRSAPAAAAAA 334
               PP P  SSS P      H  D     ++ P P   ++   A        P ++A  
Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSD-----ALTPPPLPPSNNLPAHPGPASQPPVSSATM 295

Query: 335 PPPSTLNPTSGSLLNAVDGGPSHFLASA--TAAARAQRSEVRYNQRSQISRTRSCLKRNA 392
             P  L P  G+      G P  FLAS+  +AAA+AQ   +      Q  R R+     A
Sbjct: 296 HLPLVLGPLGGAPTVEGPGAPP-FLASSLLSAAAKAQHPPLPPPSTLQGRRPRA----QA 350

Query: 393 SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQA---VSSGHTRCEKRADTA 449
            S+SHSS+   P  +R R P +    L     +T     P+A   V    +  E      
Sbjct: 351 PSASHSSSL-RPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPIL 409

Query: 450 PGQTL---APRGGSPRSQASRPHINSALHV-EDKAISDCRPSRPSHTLS----------- 494
           P        P  G   S  S   + S  H+     +S   P +P H +            
Sbjct: 410 PSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSL 469

Query: 495 SLATGASRGPPVSKAPTMDAQQDRPKSQDCLGL-------LAPLASAAELPSTAPVSGKK 547
           S   GA   P  SKAP + +   +  S+  LG+       L PLA     P  +P  G  
Sbjct: 470 SSVPGAPAPPAASKAPVVPSPVLQSPSEG-LGMGAGPACPLPPLAGGEAFPFPSPEQGLA 528

Query: 548 HRPPG-PLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAA 606
               G P    + PLP +      S  +   +    T            P    P    A
Sbjct: 529 LSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLA 588

Query: 607 APPP--------STLNPTSGSLLNAVDEGPSHFLAS 634
              P        S L P    LL      PS+ LAS
Sbjct: 589 PGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLAS 624



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 43/195 (22%), Positives = 67/195 (34%), Gaps = 25/195 (12%)

Query: 684 GPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPR---GGSPRSQASRP 740
           GPAS      L +    +        S +T C  + ++PG+  +P+     SP   ++RP
Sbjct: 90  GPASEEDMTKLCNHRRKAVAMATLYRSMETTC--SHSSPGEGASPQMFHTVSPGPPSARP 147

Query: 741 RIN-----------SALHVEDKAISDCRPSR-------PSHTLSSLATGASGGPPVSKAP 782
                          +L  E  ++S   P+        P      + +G S  P     P
Sbjct: 148 PCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRF--LP 205

Query: 783 TMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSGD 842
             +A    P     + L AP  +      ++ V      PP P  SSS P      H  D
Sbjct: 206 RGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSD 265

Query: 843 SAQDTSLIPAPFTPA 857
           +     L P+   PA
Sbjct: 266 ALTPPPLPPSNNLPA 280


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 109/450 (24%), Positives = 144/450 (32%), Gaps = 47/450 (10%)

Query: 223 LSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLA---SAAEVSSTAPVSGKKQR 279
           L+  A G  G      AP     +         G  AP A   S   VSS    SG  + 
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR- 116

Query: 280 PPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPST 339
            PGPL      + A  + +R  A       AP  +A   AG RR  S P     +P  + 
Sbjct: 117 -PGPLGQKGLRISAEETVARGKAT-----EAPKRSAL-SAGARRDTSGPTPGTPSPAMAR 169

Query: 340 LNPTSGSLLNAVDGGPSHFLASATAAAR---AQRSEVRYNQRSQISRTRSC----LKRNA 392
            +  +G+ +      PS      T   R   +  SE    + S  +R R      L+R A
Sbjct: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 229

Query: 393 SSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQ 452
           S S  SS   L     R GP++     A +        G QA+         R D AP  
Sbjct: 230 SRSLSSSATPLSS-PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT-PPRKDAAPA- 286

Query: 453 TLAPRGGSPRSQAS---------------------RPHINSALHVEDKAISDCRPSRPSH 491
            L P   SP +  S                      P   +   +    +       PS 
Sbjct: 287 -LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345

Query: 492 TLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPP 551
            LS LAT   + PP    P + A    P S     L  P   A    +   +      PP
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405

Query: 552 GPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPS 611
            P   +    PA+   S  SA   S  P    A           P  S P + +A PPP 
Sbjct: 406 SPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATPPPQ 461

Query: 612 TLNPTSGSLLNAVDEGPSHFLASATAAARA 641
              P +   L      P    A AT   +A
Sbjct: 462 APPPLAAPPLQLAKPPPQAPPALATPPLQA 491



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 78/342 (22%), Positives = 112/342 (32%), Gaps = 11/342 (3%)

Query: 35  RDNGGLSPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTK--RNAISSSYSSTGGLP 92
           RD  G +P  P P   +    A  +E+   + + ++     T+  R ++SS+   +   P
Sbjct: 153 RDTSGPTPGTPSPAMARRS-RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211

Query: 93  GLKQRRGPASS---RCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRG--G 147
               RR P++    +   + S S + +     A S    R    A   P Q   P+G   
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQA 270

Query: 148 SPRSQASRPRRRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLH-LEKQAAFQRINSALHV 206
               Q + PR+   P L      PL  P P           L  L    A     +   +
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330

Query: 207 EDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAE 266
               +       PS  LS LAT     PP    P + A    P S     L  P   A  
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390

Query: 267 VSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRS 326
             +   +      PP P   +    PA+   S  SA   S  P    A           S
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQVPPSPPAS 449

Query: 327 APAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARA 368
            P + +A PPP    P +   L      P    A AT   +A
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 97/441 (21%), Positives = 141/441 (31%), Gaps = 50/441 (11%)

Query: 446 ADTAPGQTLAPRGGSPR-----SQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGA 500
           A  APG       GSPR     + A+   + +A  V  K +++        T+   A  A
Sbjct: 18  AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77

Query: 501 SRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDP 560
             GP  +  P    + +R           P  + +  P ++P        PGPL      
Sbjct: 78  --GPTRTSRPPASGRGERAP---------PAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126

Query: 561 LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAA----AAAPPPSTLNPT 616
           + A  + +R  A       A    A RD       PGT +PA A    AA        P 
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTS--GPTPGTPSPAMARRSRAAGTEVGLPRPA 184

Query: 617 SGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGL 676
             +      EGP   ++SA+  +    S     + S        L+R AS S  SS   L
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG----LQRPASRSLSSSATPL 240

Query: 677 QELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPRSQ 736
                R GP++     A +  +     G QA+        + D AP   L P   SP + 
Sbjct: 241 SS-PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA--LGPLSSSPLAT 297

Query: 737 AS---------------------RPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGG 775
            S                      P   +   +    +       PS  LS LAT     
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 776 PPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPA 835
           PP    P + A    P S     L  P   A    +   +      PP P   +    PA
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 836 TSSHSGDSAQDTSLIPAPFTP 856
           +   S  +   +   P+   P
Sbjct: 418 SPPVSPSATPPSQAPPSLAAP 438



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 122/532 (22%), Positives = 180/532 (33%), Gaps = 76/532 (14%)

Query: 114 TVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPLLPSRRGEPLM 173
           T+ E  P+A   G TR  +   +  G+   P   +     S P R      P   G+   
Sbjct: 69  TIPESAPRA---GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK-- 123

Query: 174 MPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKA-ISDCRPSRPSHTLS--SLATGA 230
                  G R++AE+     +A      SAL    +   S   P  PS  ++  S A G 
Sbjct: 124 -------GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176

Query: 231 SGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFSSSDP 290
             G P   AP+    + RP ++   G    ++SA+E S+T P    ++RP     S+   
Sbjct: 177 EVGLP-RPAPSA---RPRPPTE---GPRKSVSSASEHSTTEPSPAARRRP-----SAGGG 224

Query: 291 LPATSSHSRDSAQVTSMIPA---PFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSL 347
           L   +S S  S+      PA   P    +  A    ++  P    A  PP    P   + 
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA- 283

Query: 348 LNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTE-GLPEL 406
             A   GP      AT +  A  S       S     ++     A+  S ++T  G P L
Sbjct: 284 --APALGPLSSSPLATPSPSAPPSP------SAPPSLQTLPSPPATPPSQATTSLGSPTL 335

Query: 407 KRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQAS 466
           +      ++H  L       ++   PQA  +      +   + P         +P  QA 
Sbjct: 336 Q------ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389

Query: 467 RPHINSALHVEDKAISDCRPSRP---------SHTLSSLATGASRGPPVSKAPTMDAQQD 517
                 A+H+     S   PS P         S  +S  AT  S+ PP   AP +     
Sbjct: 390 NA---LAVHLLQAPFSP-PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 518 RPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSM 577
            P S        P   A    +  P+   K  P  P   ++ PL A  S           
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---------- 495

Query: 578 IPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPS 629
            PA F       G     P  S P +  A PPP      +  LL      P+
Sbjct: 496 -PASFP------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 137/609 (22%), Positives = 212/609 (34%), Gaps = 106/609 (17%)

Query: 45  PRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGL-PGLKQRRGPASS 103
           PR GP +T     S         + +  + +T    +SS   ++G   PG   ++G   S
Sbjct: 75  PRAGPTRTSRPPASGR------GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128

Query: 104 RCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPRSQASRPRRRKIPL 163
             + T++  K     +  A+S+G  R           T  P  G+P    +R  R     
Sbjct: 129 -AEETVARGKATEAPKRSALSAGARR----------DTSGPTPGTPSPAMARRSRAAGTE 177

Query: 164 LPSRRGEPLMMPPPLELGYRVT----AEDLHLEKQAAFQRINSALHVEDKAISDCRPSRP 219
           +   R  P   P P   G R +    +E    E   A +R  SA     +  S    S  
Sbjct: 178 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS-- 235

Query: 220 SHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQ---------------DCLGLVAPLASA 264
             + + L++ A  GP     P   A   +PK +               D    + PL+S+
Sbjct: 236 --SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293

Query: 265 AEVSSTAPVSGKKQRPPG----PLFSSSDPLPATSSHSRDSAQVT-SMIPAPFTAA---- 315
              + +         PP     P   ++ P  AT+S    + Q T S +P+P  +     
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353

Query: 316 ---SRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSE 372
              +  A       AP +  A+PP S L   S    NA+     H L +  +   +   +
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL---AVHLLQAPFSPPPSPPVQ 410

Query: 373 VRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGP 432
             ++  +    + S    + +  S ++    P L+    P +S      S S T     P
Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAA----PPLQVPPSPPASPPM---SPSATPPPQAP 463

Query: 433 QAVSSGHTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHT 492
             +++            P Q   P   +P + A+ P    AL     +     P  PS +
Sbjct: 464 PPLAA-----------PPLQLAKPPPQAPPALATPPL--QALPSPPASFPGQAPFSPSAS 510

Query: 493 L--SSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKK--- 547
           L  S LAT   + PPV  AP +      P S     L AP       P T+ VSG +   
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT---LQAPRRPPTPGPDTS-VSGPRLTL 566

Query: 548 ----HRPPGPLFSSSDPL--PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAP 601
                 PP P  S S  L  P  + HS      +S    P      D+G           
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHS------SSATSTPEELRGYDSG---------PE 611

Query: 602 AAAAAAPPP 610
             AAA+PPP
Sbjct: 612 GGAAASPPP 620


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 139/684 (20%), Positives = 229/684 (33%), Gaps = 116/684 (16%)

Query: 218  RPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPL----ASAAEVSSTAPV 273
            RP    +     AS  P     P   A +  P+  D L L A      A   ++   AP 
Sbjct: 411  RPGGRAARPTPAASATPTAQPLPQPPAPR-APEGDDFLSLHAESDGEGALQVDLGEPAPA 469

Query: 274  SGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAAS----RDAGMRRTRSAPA 329
                    G L      L       R  +   +  PAP  AA     + +   R RS  A
Sbjct: 470  PPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEA 529

Query: 330  AAAAAP-------PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQIS 382
              AA+        PP+  +P       + D  P    + A+++AR +RS  R   RS   
Sbjct: 530  KEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPG---SHASSSAR-RRSRSRSRSRSTRR 585

Query: 383  RTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRC 442
            R+RS  +R   S    S E     +RRR  +      + SSS+     G      G  + 
Sbjct: 586  RSRSTDRRRGGSRRSRSRE--KRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKK 643

Query: 443  EKRA------------DTAPGQTLAPRGG-SPRSQASRPHINSALHVEDKAISDCRPSRP 489
            +KR+            + AP     P G  S   + SR        ++D    D    + 
Sbjct: 644  KKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKR 703

Query: 490  SHTLSSLATGASRGPPVSKAPT-------------------MDAQQDRPKSQDCLGLLAP 530
            + T+  L     RGP  + A +                     +Q+DR +S    G  + 
Sbjct: 704  TITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRS----GAASS 759

Query: 531  LASAAELPSTAPV------------------SGKKHRPPGPLFSSSDP--LPATSSHSRD 570
             +S+ E  S                      S KK RPP     SS P   P  SS S  
Sbjct: 760  SSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGS 819

Query: 571  SAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLN-------PTSGSLLNA 623
            S+  +S         S+ A + R    ++ PA  AA+    ++         +    L  
Sbjct: 820  SSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKP 879

Query: 624  VDEGPSHFLASATAAARARRSQVRYNQ----------RSQTSRTRSCLKRNASSSSHSST 673
             +  P+    +A  + + ++++V+             +++ S+TR   K+  S      +
Sbjct: 880  DERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTR---KKVRSGGGSGGS 936

Query: 674  EGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSP 733
             G   LK+ +  + S       +  T      +A     T   KA   P   L P   + 
Sbjct: 937  GGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKA-APPPPALTPDSQTV 995

Query: 734  RSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKS 793
             S    P ++    + ++A  +               G  GG    +    + +++  + 
Sbjct: 996  DSSCKTPEVS---FLPEEATEEA--------------GVRGGAEEEEEEEEEEEEEEEEE 1038

Query: 794  QDCLGLVAPLASAAEVSSTAPVSG 817
            +         ++AA   STAP +G
Sbjct: 1039 EQQPATTTATSTAAAAPSTAPSAG 1062



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 65/296 (21%), Positives = 110/296 (37%), Gaps = 22/296 (7%)

Query: 579 PAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAA 638
           PAP  A S  +      P +S+P+     PPP+   P +          P+    S   A
Sbjct: 184 PAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPA 243

Query: 639 ARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLA----- 693
              +         + +S   +              E  ++ +   G + S  +++     
Sbjct: 244 PEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAG 303

Query: 694 LSSSNTVSEDGPQAVSSR-DTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKA 752
           +   N++S+D P   S R D +  +   APG    P+  S R+  +  R    +  E +A
Sbjct: 304 IYDDNSLSQDFPGDESPRPDAQPTQPTPAPG--TPPQVDSTRADGAMRRRVFVVGTEAEA 361

Query: 753 ISDCRPSRPSHTLSSLATGASGGPPV-----SKAPTMDAQQDRPKSQDCLGLVAPLASAA 807
              CR  + S  + + A GA+  PP+     S+    +  Q   + +  L L  P   AA
Sbjct: 362 ---CREGKVSVEVVT-AGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAA 417

Query: 808 E---VSSTAPVSGKKHRPPGPLFSSSDPLPATSSHS-GDSAQDTSL-IPAPFTPAS 858
                +S  P +    +PP P     D   +  + S G+ A    L  PAP  PA+
Sbjct: 418 RPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAA 473


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 109/541 (20%), Positives = 203/541 (37%), Gaps = 66/541 (12%)

Query: 269  STAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMR-RTRSA 327
            S  P +  K +   P    +D    + SHS  +   T   P   T  S+  G   R+++ 
Sbjct: 996  SRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFT---PPTSTGGSKSPGSAGRSQTP 1052

Query: 328  PAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSC 387
            P  A    P  T+    G+++       S + +S + ++   +S   ++           
Sbjct: 1053 PGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHS----------- 1101

Query: 388  LKRNASSSSHSSTEGLPELKRRRGPASSHCQLA---------HSSSKTVSEDGPQAVSSG 438
                +SSSS +ST G  +  +  G +SS    +          S SK  S+ G +  SS 
Sbjct: 1102 ----SSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSP 1157

Query: 439  HTRCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLAT 498
             T+      +    T     G P S      +N +L   + + S  RP   S  L+S   
Sbjct: 1158 ITK--HGLSSGSSSTKMKPQGKPSSL-----MNPSLSKPNISPSHSRPPGGSDKLASPMK 1210

Query: 499  GASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSS 558
                 PP SKA +  +              + + S++ L S+  +S K   PP     SS
Sbjct: 1211 PVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQK--TPP-----SS 1263

Query: 559  DPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAP----AAAAAAPPPSTLN 614
            +   A+SS    S    S       ++   +  R  +P  +A             P   +
Sbjct: 1264 NSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGED 1323

Query: 615  PTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTE 674
            P  G +      G S   +S   +++   S   +    Q  R +S   ++  S+S SS +
Sbjct: 1324 PLDGQM------GVSTNSSSHPMSSKHNMSGGEF----QGKREKSDKDKSKVSTSGSSVD 1373

Query: 675  GLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSPR 734
              ++    +   S+     + S +   + G  ++ ++ T  +K   + G+ L P+  S +
Sbjct: 1374 SSKKTSESKNVGSTGVAKIIISKH---DGGSPSIKAKVT-LQKPGESSGEGLRPQMASSK 1429

Query: 735  SQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQ 794
            +  S P I+ +    ++  S      P++T  +L + +  G  +++     + Q+ P S 
Sbjct: 1430 NYGS-PLISGSTPKHERG-SPSHSKSPAYTPQNLDSESESGSSIAE----KSYQNSPSSD 1483

Query: 795  D 795
            D
Sbjct: 1484 D 1484



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 70/325 (21%), Positives = 121/325 (37%), Gaps = 41/325 (12%)

Query: 539  STAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGT 598
            S  P +  K +   P    +D    + SHS  +   T       + +   AG  +T PG 
Sbjct: 996  SRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGV 1055

Query: 599  SAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTR 658
            + P       P  T+    G+++       S + +S + ++               S ++
Sbjct: 1056 ATPPI-----PKITIQIPKGTVMVGKPSSHSQYTSSGSVSS---------------SGSK 1095

Query: 659  SCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLAL---------SSSNTVSEDGPQAVS 709
            S    ++SSSS +ST G  +  +  G +SS    ++         S S   S+ G +  S
Sbjct: 1096 SHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGS 1155

Query: 710  SRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLA 769
            S  T+   +  +    + P+ G P S      +N +L   + + S  RP   S  L+S  
Sbjct: 1156 SPITKHGLSSGSSSTKMKPQ-GKPSS-----LMNPSLSKPNISPSHSRPPGGSDKLASPM 1209

Query: 770  TGASGGPPVSKAPTM------DAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPP 823
                G PP SKA +        +      S   +   + L S+  +S   P S       
Sbjct: 1210 KPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTAS 1269

Query: 824  GPLFSSSDPLPATSSHSGDSAQDTS 848
               FSSS    ++S +   S++  S
Sbjct: 1270 SSSFSSSGSSMSSSQNQHGSSKGKS 1294


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/306 (24%), Positives = 107/306 (34%), Gaps = 36/306 (11%)

Query: 355 PSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRR-GPA 413
           P    A+AT AA A  S    + +  I  T   L+   S  +    E +  + RRR GP 
Sbjct: 9   PPETAAAATTAAAASSSAASPHYQEWILDTIDSLR---SRKARPDLERICRMVRRRHGPE 65

Query: 414 SSHCQ------LAHSSSKTVSEDGPQAV-SSGHTRCEKRADTAPGQTLAPRGGSPRSQAS 466
               +      +   +   VS  G  +  ++   +  +R  T P    APRG    + A+
Sbjct: 66  PERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAA 125

Query: 467 RPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLG 526
            P    A       ++   P+R     ++ AT      P S  P     Q  P++Q    
Sbjct: 126 APPPTPAPPPPPAPVAAAAPARAPRAAAAAATA-----PPSPGPA----QPGPRAQRAAP 176

Query: 527 LLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAAS 586
           L AP  + A  P+ AP +G +  PP  + +   PLP          Q     P P     
Sbjct: 177 LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQP----- 231

Query: 587 RDAGMRRTRPGTSAPAAAAAAPPPSTLNPT-----SGSLLNAVDEGPSHFLASATAAARA 641
                 +  P   A  A  AA P S          SG     +  G    L    AAAR 
Sbjct: 232 ------QPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARG 285

Query: 642 RRSQVR 647
           R  + R
Sbjct: 286 RLERTR 291



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 61/280 (21%), Positives = 96/280 (34%), Gaps = 26/280 (9%)

Query: 602 AAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCL 661
           A   A PPP T    + +   +      H+         + RS+     R    R    +
Sbjct: 2   AGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSR---KARPDLERICRMV 58

Query: 662 KRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTA 721
           +R        +   L++L ++R       + ++S  N      P+          +  T 
Sbjct: 59  RRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPR----------RGATP 108

Query: 722 PGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKA 781
           P    APRG    + A+ P    A       ++   P+R     ++ AT      P S  
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATA-----PPSPG 163

Query: 782 PTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSDPLPATSSHSG 841
           P     Q  P++Q    L AP  + A   + AP +G +  PP  + +   PLP       
Sbjct: 164 PA----QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219

Query: 842 DSAQDTSLIPAPFTP----ASRDAGVRRMFCVRNCLRGLG 877
              Q     P P  P    A R  G  R   +R  +R LG
Sbjct: 220 PPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLG 259



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 4/66 (6%)

Query: 227 ATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQRPPGPLFS 286
           A  A+   P S  P     Q  P++Q    L AP  + A   + AP +G ++ PP  + +
Sbjct: 151 AAAAAATAPPSPGPA----QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA 206

Query: 287 SSDPLP 292
              PLP
Sbjct: 207 REPPLP 212



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 1/64 (1%)

Query: 308 IPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAAR 367
           +  P   A+  A  R  R APAAAAAA PP T  P       A    P+    +A AAA 
Sbjct: 99  VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAA-AAPARAPRAAAAAAT 157

Query: 368 AQRS 371
           A  S
Sbjct: 158 APPS 161


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 108/519 (20%), Positives = 184/519 (35%), Gaps = 55/519 (10%)

Query: 355  PSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPAS 414
            PS    +       +  + + +++ ++S   S +KR+ S +  SS +      ++  P+S
Sbjct: 990  PSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE----SKKPLPSS 1045

Query: 415  SHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAPGQTLA--PRGGS--PRSQASRPHI 470
            S    A+++S    +    A             T+   TL   P+  +   RS   +  +
Sbjct: 1046 SRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSM 1105

Query: 471  NSALHVEDKAIS-DCRPSRPSHTLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLA 529
            + A + +D  ++   R +    +L   +   SR    +++ T     D   S    GL  
Sbjct: 1106 DGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI--DSNISSKSAGL-- 1161

Query: 530  PLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRDA 589
            P+    E   TA  S      PG L + +D     SS +   A   S+   P        
Sbjct: 1162 PVPKLREPSKTALGSSL----PG-LVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 1216

Query: 590  GMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYN 649
                 +PG   P  A+    P+      G     V    +  + ++   +    +  +  
Sbjct: 1217 AQTSLQPGAKYPDVAS----PTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 1272

Query: 650  QRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLA--------LSSSNTVS 701
                 S +   L   +SS  +S    L +      P+S+H   +         SSS+ VS
Sbjct: 1273 NLDSPSGS-GVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVS 1331

Query: 702  EDGP--QAVSSRDTRCEKADTAPGQTLAPRGGSPRSQASRPRINSALHVEDKAISDCRPS 759
            +DG   Q+VSS  T CE  D +        GG P   +S   I S+   +D      R +
Sbjct: 1332 KDGLGFQSVSSLHTSCESIDISLSS-----GGVPSHNSSTGLIASSK--DDSLTPFVRTN 1384

Query: 760  RPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK 819
                TLS     +    P     T+  +QD     D               +T P  G +
Sbjct: 1385 SVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLD--------------RNTLPKKGLR 1430

Query: 820  HRPPGPLFSSSDPLPATSSHSGDSAQDTSLIPAPFTPAS 858
            + P   L +  D      SHS    QDT+   +PF+  S
Sbjct: 1431 YTPTSQLRTQEDAKEWLRSHSAGGLQDTA-ANSPFSSGS 1468



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 88/416 (21%), Positives = 143/416 (34%), Gaps = 86/416 (20%)

Query: 515 QQDRPKSQDCLGLLAPLAS-AAELPSTAPVSGKKHRPPGPLFSSSDP-LPATSSHSRDSA 572
           QQ +P+ Q     L P  S  A  PS       + + P    +   P  PA    S+  A
Sbjct: 129 QQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQA 188

Query: 573 QVTSMIPAPFTAASRDAGMRRTRPGTSA-------------------------------P 601
           ++ S +P P    S      +TR G++                                P
Sbjct: 189 EMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEP 248

Query: 602 AAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASAT-----AAARARRSQVRYNQRSQTSR 656
            A++A+  P   +    SL +     P++   S+      AA +  RS+    + S T  
Sbjct: 249 LASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVS 308

Query: 657 TRSCLKRNASSSSHSSTEGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCE 716
             S +K     +   + E ++     +       +L  S   + + +GP    SRDT CE
Sbjct: 309 MLS-VKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP---GSRDTSCE 364

Query: 717 KADTAPG--------------QTLAPRGGSPR--------SQASRPRIN--SALHVEDKA 752
           + +T P                T+ P   SP+           SR   N  S+L   +K 
Sbjct: 365 RLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKE 424

Query: 753 ISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAP--LASAAEVS 810
               +  +       LA  A      S    +D +++ PK +D  G   P     +++++
Sbjct: 425 KEKQQREKDKEKSKDLAKRA------SVTERLDLKEE-PK-EDPSGAAVPEMPKKSSKIA 476

Query: 811 STAPVSGKKHRPPGPLFSSSDPLPATSSHSGDSAQDTSLIP--APFTPASRDAGVR 864
           S  P  GK         +S+   P   SHSG        +P  +P  PA    G R
Sbjct: 477 SFIPKGGK--------LNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGER 524



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 43/192 (22%), Positives = 66/192 (34%), Gaps = 3/192 (1%)

Query: 245 QQDRPKSQDCLGLVAPLAS--AAEVSSTAPVSGKKQRPPGPLFSSSDPLPATSSHSRDSA 302
           QQ +P+ Q     + P  S  A   S     + ++Q P  P        PA    S+  A
Sbjct: 129 QQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQA 188

Query: 303 QVTSMIPAPFTAASRDAGMRRTRSAPAAAAAAPPPSTLNPTSGSLLNAVDGGPSHFLASA 362
           ++ S +P P    S      +TR     A      S  N      + +    PS      
Sbjct: 189 EMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEP 248

Query: 363 TAAARAQRSEVRYNQRSQISRTRSCLKRNASSSSHSSTEGLPELKRRRGPASSHCQLAHS 422
            A++ +    +  N  + +    S    N S+SS     G    K  R  + S    A  
Sbjct: 249 LASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPG-AATKPWRSKSLSVKHSATV 307

Query: 423 SSKTVSEDGPQA 434
           S  +V   GP+A
Sbjct: 308 SMLSVKPPGPEA 319


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.123    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,362,977
Number of Sequences: 37866
Number of extensions: 2253069
Number of successful extensions: 15364
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 777
Number of HSP's that attempted gapping in prelim test: 11629
Number of HSP's gapped (non-prelim): 3597
length of query: 896
length of database: 18,247,518
effective HSP length: 111
effective length of query: 785
effective length of database: 14,044,392
effective search space: 11024847720
effective search space used: 11024847720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.