BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116292168 KRAB A domain containing 1 [Homo sapiens] (1030 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116292168 KRAB A domain containing 1 [Homo sapiens] 2167 0.0 gi|163965366 nascent polypeptide-associated complex alpha subuni... 91 6e-18 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 81 6e-15 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 78 4e-14 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 9e-13 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 72 2e-12 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 70 1e-11 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 70 1e-11 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 68 4e-11 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 3e-10 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 65 4e-10 gi|150170670 piccolo isoform 2 [Homo sapiens] 65 4e-10 gi|150378539 piccolo isoform 1 [Homo sapiens] 65 4e-10 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 64 6e-10 gi|55750053 atrophin-1 [Homo sapiens] 64 7e-10 gi|55750041 atrophin-1 [Homo sapiens] 64 7e-10 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 63 2e-09 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 62 4e-09 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 62 4e-09 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 62 4e-09 gi|188536004 zinc finger protein 469 [Homo sapiens] 62 4e-09 gi|95147555 microtubule-associated protein 1A [Homo sapiens] 58 5e-08 gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 57 7e-08 gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 57 7e-08 gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 57 7e-08 gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 57 7e-08 gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 57 7e-08 gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 57 7e-08 gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 57 7e-08 gi|48762934 alpha 2 type I collagen [Homo sapiens] 56 2e-07 >gi|116292168 KRAB A domain containing 1 [Homo sapiens] Length = 1030 Score = 2167 bits (5615), Expect = 0.0 Identities = 1030/1030 (100%), Positives = 1030/1030 (100%) Query: 1 MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLH 60 MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLH Sbjct: 1 MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLH 60 Query: 61 LTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCL 120 LTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCL Sbjct: 61 LTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCL 120 Query: 121 PDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPT 180 PDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPT Sbjct: 121 PDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPT 180 Query: 181 HSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLG 240 HSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLG Sbjct: 181 HSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLG 240 Query: 241 TSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQEN 300 TSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQEN Sbjct: 241 TSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQEN 300 Query: 301 PGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATG 360 PGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATG Sbjct: 301 PGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATG 360 Query: 361 DTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRS 420 DTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRS Sbjct: 361 DTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRS 420 Query: 421 QKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGS 480 QKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGS Sbjct: 421 QKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGS 480 Query: 481 PVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTAD 540 PVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTAD Sbjct: 481 PVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTAD 540 Query: 541 KEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRW 600 KEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRW Sbjct: 541 KEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRW 600 Query: 601 LPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEP 660 LPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEP Sbjct: 601 LPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEP 660 Query: 661 DLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQD 720 DLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQD Sbjct: 661 DLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQD 720 Query: 721 PCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAA 780 PCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAA Sbjct: 721 PCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAA 780 Query: 781 PPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGR 840 PPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGR Sbjct: 781 PPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGR 840 Query: 841 RPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDL 900 RPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDL Sbjct: 841 RPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDL 900 Query: 901 QGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSP 960 QGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSP Sbjct: 901 QGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSP 960 Query: 961 LPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGG 1020 LPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGG Sbjct: 961 LPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGG 1020 Query: 1021 EHRDPRWGAH 1030 EHRDPRWGAH Sbjct: 1021 EHRDPRWGAH 1030 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 90.9 bits (224), Expect = 6e-18 Identities = 225/997 (22%), Positives = 316/997 (31%), Gaps = 162/997 (16%) Query: 85 SPESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPT 144 +P S G + + +P AA P P G + P G + P A TP S GP Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP--AATP--PSPKGGPA 1001 Query: 145 GDGVQGSPLPIKTADKPWPTRKEGPGAL---GGEPSPPTHSPSRRKSHRGQERGTSEAGI 201 +G+P P P+ K P A G +PP +P K Sbjct: 1002 TPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKG------------- 1045 Query: 202 SPGNSPLQGLINCLKEILVPGPRHPETSPSFL-PPLPSLGTSRLTRADLGPGSPPWAVKT 260 SP +PL +P P+ +PS P P T + SP A Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105 Query: 261 EAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGP----GYLLT 316 A + P GL + PS G GA + P G L T Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165 Query: 317 PPPH---------PDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVP- 366 PPP P GGL + + +P PA+ P P AT +G P Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKG----APTTPAATPP--SPKGGLATPSPKGAPT 1219 Query: 367 QPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPEL- 425 P+ P + ++ + PP+ PP + P S K L Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279 Query: 426 -QPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGN 484 PH+ A P P G GP+ P+G PT +++ SP G+ Sbjct: 1280 TPPHKGAPNPAVVTPPSPKG-------GPATS-PPKGAPTPPAATPP--------SPKGS 1323 Query: 485 QGQHPGKG--SPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRG----PRRAE---PR 535 G P KG +PP +P P P P P ++ + +G P E P Sbjct: 1324 PGTPPPKGAPTPPAVTP-----------PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372 Query: 536 NWTADKEGLRAEACESARLGQG----RGEAPTRSLHLVSPQVFTSSCV----PACHQRGF 587 T +G A S + G +G+ + ++ +SP+ ++ V A +G Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432 Query: 588 KDPGATRPGVWRWLPEGSAPK---PSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGS 644 P A P + P SAPK +P + L + P P P+P S Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE-----PPAPKQVATS 1487 Query: 645 SSSFSGSEGEDPRPEPDLWKPLPQERDRLP-----------------SCKPPVPLSPCPG 687 SS P P L +P +P S K P L+P Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547 Query: 688 GTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPV---SQLEKRPRVSEASRGLELGH 744 P + SP + P P+ + P S + P E + Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607 Query: 745 GRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPP-------CHCGK 797 P+ A T + P P + P+ P P +PPV P+S P C G Sbjct: 1608 PSPK-EAPTPPAVTPPSPEKGPATPAPKGTP---TSPPVTPSSLKDSPTSPASVTCKMGA 1663 Query: 798 PLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQ-------------- 843 + Q S G + L L A E + T R G + + Sbjct: 1664 TVPQA--SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721 Query: 844 ----GPGPMGQASWMWTLP---RGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCR 896 GP+ + LP + A G H P KGP P + Sbjct: 1722 AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP----KGPLAPPESKASTPLTAAA 1777 Query: 897 AGDLQGLSRGTARRARPLPPDAPPAEP-PGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTG 955 + + A P PP + P P P QQ L S+P P+ PL Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837 Query: 956 GHQSPLPPLVP--AALPLQGA---SPPAASADADVPT 987 PL P P +P Q P SA VPT Sbjct: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPT 1874 Score = 83.2 bits (204), Expect = 1e-15 Identities = 212/959 (22%), Positives = 290/959 (30%), Gaps = 180/959 (18%) Query: 102 PEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPL--PIKTAD 159 P A + + C L P+ P S P + P + + DG+ + P+ ++ Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV-DGISHTSALAPVASSP 767 Query: 160 KPWPTRKEG-----------------PGALGGEPSPPTHSPSRRKSHRGQERGTS----- 197 K PT G P LG SP T P +K G + Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827 Query: 198 ----EAGISPGNS-PLQGLINCLKEILVPGPRHPE--TSPSFLPPLPSLGTSRLTRADLG 250 EA P NS QG + P P P+ +PS + PL G + + Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887 Query: 251 PGSPPWAVKTEAVSGDCPLQG-LLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSG 309 P E + P Q L P+ P+P G+ A G Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP---------ASPSPKG 938 Query: 310 GPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPS 369 P PP P GPA+ P P P+AT P P Sbjct: 939 APTPPAATPPSPK-------------------GGPATPSPKWAPTPPAATP-----PSPK 974 Query: 370 WGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHR 429 GP + + +P A KG P SP P P P S + P + Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPAT-PSPKGAPTPPAVTPPSPKGSPAATPF---PK 1030 Query: 430 SHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHP 489 S P P G P+ P+G PT+ +++ SP G Sbjct: 1031 GASTPPAATPPSPKG-------SPAATPLPKGAPTTPAAT--------LPSPKGGPATPS 1075 Query: 490 GKGSP--PGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAE 547 KG+P P ++P P P PA P A P P + K GL Sbjct: 1076 LKGAPTPPAATP-----------PSPKGGPATPSPKGAPMPPAATPP----SPKGGLATP 1120 Query: 548 ACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDP----GATRPGVWRWLPE 603 + A PT T + P + G P T P P+ Sbjct: 1121 PHKGA---------PT-----------TPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160 Query: 604 GSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLW 663 G P P + A P + PSP +P + ++ P P+ L Sbjct: 1161 GGLATPPP----KGAPTTPAATPPSPKGGLATPSPKGAPTTPAA------TPPSPKGGLA 1210 Query: 664 KPLPQERDRLPSCKPPVP----LSPCPGGTPA--GSSGGSPGEDPRRTEPRYCSGLGAGT 717 P P+ P+ PP P +P P G P ++ SP P P+ GA T Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK-----GAPT 1265 Query: 718 AQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPP 777 P S + G P A T P P P+ SPP P P Sbjct: 1266 PPAATPPSL--------KGGLATPPHKGAPNPAVVT-----PPSPKGGPATSPPKGAPTP 1312 Query: 778 EAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNR 837 AA P P S P G P A T A T ++ Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPP------AVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366 Query: 838 LGRRPQGPGPMGQASWMWTLP---RGPRWAHGPGHRHLPYWRQKGPTR-PKPKILRGQGE 893 G P P + T P RGP G P P + P + R Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426 Query: 894 SCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAH 953 + GDL + + AP P L + TP PPA +A Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486 Query: 954 TGGHQ----SPLP---PLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSL 1005 + + +P P P +PA +P PA + P +AP K P++L Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP---IAPTATLLSKKTPATL 1542 Score = 74.7 bits (182), Expect = 4e-13 Identities = 164/719 (22%), Positives = 230/719 (31%), Gaps = 133/719 (18%) Query: 85 SPESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPT 144 +P S G + + +P A P P G + P G + P AT P+ P Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP-AATPPSPKGSPGTPP 1328 Query: 145 GDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHS-----PSRRKSHRGQERGTSEA 199 G P + K PT + G P+ P+ P+ SH+G G + Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG---GPAMT 1385 Query: 200 GISPGNSPLQGLINCLKEILVPGPRHPETSPSFLP---------PLPSLGTSRLTRADLG 250 SP P +P P+ TSP+ +P P+ G + ++ DL Sbjct: 1386 PPSPKRGPA-----------IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434 Query: 251 P--------------GSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRR 296 P +P T + GD L + P + P+P V Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT------PPSPKEPPAPKQVATSS 1488 Query: 297 LQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVK---MENSWVQSPPGPASCQPGRQP 353 + A G P P P S + + + S PA+ P Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548 Query: 354 LSPSAT----GDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQL--PPT 407 + P+ T T +P P P ++ +SSP + KG P SP +L PP Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP----SPKELLIPPA 1604 Query: 408 SCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTS-- 465 S +P+ P P GP+ P AP+GTPTS Sbjct: 1605 VTSPSPKEA----------------------PTPPAVTPPSPEKGPATP-APKGTPTSPP 1641 Query: 466 FSSSSSTDWDLDFGSPVGNQGQ---HPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCS 522 + SS D S G KG P P LKE+ ++ PA P S Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP-----TALKEV---LVAPA-PES 1692 Query: 523 SAADRGPRRAEPRNWTADKEGLRAEACESARLGQG-RGEAPTRSLHLVSPQVFTSSCVPA 581 + P R P+ T C G +G T + + P SS Sbjct: 1693 TPIITAPTRKGPQ--TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750 Query: 582 CHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLE-------SALRGILPVRPLRFACVG 634 G P PE A P E SA P P+ Sbjct: 1751 GKDASHSPKGPLAP------PESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA- 1803 Query: 635 GPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPL-PQERDRLPSCKPPVPLSPCPGGTPAGS 693 PSP P+ F S P KPL P + D L PP P+S GG P S Sbjct: 1804 -PSPVPTLPPKQQFLPSSPGLVLESPS--KPLAPADEDELLPLIPPEPIS---GGVPFQS 1857 Query: 694 ---------SGGSPGEDPRRTEPRYCSGLGAGTAQDPC-PVSQLEKRPRVSEASRGLEL 742 S G P P +P + G+GT D V +LE++ ++ +L Sbjct: 1858 VLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQL 1916 Score = 62.4 bits (150), Expect = 2e-09 Identities = 171/706 (24%), Positives = 221/706 (31%), Gaps = 135/706 (19%) Query: 343 GPASCQPGRQPLSPSATGDTRGVPQPSWG-PEAQAASASSSPLEALEACLKGIPPNGSSP 401 G S P P+ VP S P A + + +PL L + IP + SP Sbjct: 679 GTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE-IPKSVPSP 737 Query: 402 SQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRG 461 S LPP + D S L P S +E E G S + +G Sbjct: 738 S-LPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED-----------SGASATASSKG 785 Query: 462 TPTSFSSSSSTDWDLDFGSPVGNQGQHPG--KGSPPGSSPLQGL-------------ENC 506 T T + S S G V Q + P KGS +P+ L EN Sbjct: 786 TLTYLADSPSP-----LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840 Query: 507 L-----KEIPVPVLRPAWPCSSAADRG-------------PRRAEPR----NWTADKEGL 544 L K+ P P P A P + P N KEG Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900 Query: 545 RAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEG 604 A + A +P ++ +P+ +S P +G P A P P+G Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP----KGAPTPPAATPPS----PKG 952 Query: 605 SAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWK 664 PSP P P PSP P + S P P P Sbjct: 953 GPATPSPKWA---------PTPP----AATPPSPKGGPATPSPKGA-----PTP-PAATP 993 Query: 665 PLPQERDRLPSCK----PPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQD 720 P P+ PS K PP P P G+PA + P P G A T Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053 Query: 721 ---PCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPP 777 P + P+ A+ L+ G P A T P+G P PS P P P Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLK---GAPTPPAATPPS--PKGGPATPS---PKGAPMP 1105 Query: 778 EAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNR 837 AA P P L P H G P + A LAT A + Sbjct: 1106 PAATPPSPKGGLATPPHKGAPT-----TPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160 Query: 838 LGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRA 897 G P P G + P P+ G P PK + Sbjct: 1161 GGLAT--PPPKGAPTTPAATPPSPK---------------GGLATPSPKGAPTTPAATPP 1203 Query: 898 GDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGH 957 GL+ + + A P PP+ GL S + P+ AA P P GG Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK----GAPTTPAATPPSP----KGGP 1255 Query: 958 QSPLP---PLVPAALP--LQG--ASPPAASADADVPTSGVAPDGIP 996 +P P P PAA P L+G A+PP A + +P G P Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 80.9 bits (198), Expect = 6e-15 Identities = 238/1005 (23%), Positives = 333/1005 (33%), Gaps = 183/1005 (18%) Query: 95 LDGERASPEA-AAAREPCPLR-GLLSCLPDG-PTSQPHLATTPTDSSCSSGPTG------ 145 +D +R +A AAAR P GLL+ P G P P + ++G G Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 146 --DGVQGSPLPIKTADKPWPTRKEG----------PGALGGEPSPPTHSPSRRK-SHRGQ 192 G+ G+ +P ++A + PTR G P + GE +PP + S S G+ Sbjct: 61 RAGGIGGATIP-ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119 Query: 193 ERGTSEAG--------ISPGNSPLQGLINCL--KEILVPGPRHPETSPSFLPPLPSLGT- 241 GT+ G IS + +G + L G R + P+ P P++ Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179 Query: 242 SRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENP 301 SR ++G P + + P +G + E PSP+ RR Sbjct: 180 SRAAGTEVGLPRPAPSARPRP-----PTEGPRKSVSSASEHSTTEPSPAA--RRRPSAGG 232 Query: 302 GAWKRGS---------------GGPGYLLTP--PPHPDL----GAGGLLSVKMENSWVQS 340 G + S GP TP P HP G L ++ + Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292 Query: 341 PP--GPASCQPGRQPLSPSATG-------DTRGVPQPSWGPEAQAASAS---SSPLEALE 388 P GP S P P SPS T D P P+ P + + + P + Sbjct: 293 APALGPLSSSPLATP-SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351 Query: 389 ACLKGIP-PNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQS 447 L+ +P P + PSQ PP+ + Q S P +Q S + + + P PL L S Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411 Query: 448 CVRDGPSRPLAPRGTPT-----SFSSSSSTDWDLDFGSPVGNQGQHPGKG------SPPG 496 + G+PT SF + S SP P S P Sbjct: 412 L------QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465 Query: 497 SSPLQ-GLENCLKEIPVPV-LRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARL 554 S PLQ L + + P+ + P SS A P+ E + A S + Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525 Query: 555 GQGRGEAP--------------TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRW 600 P T S L +P + T C C + P T P Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP----- 580 Query: 601 LPE-----GSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGED 655 PE + P +P L+G LP PL + + P P P + + Sbjct: 581 -PETPSSIATPPPQAPPALASPPLQG-LPSPPL--SPLATPPPQAPPXLALPPLQAPPSP 636 Query: 656 PRPEP--DLWKPLPQERDRL-------PSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTE 706 P P L P PQ + L P PP P P PA SP P T Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA-----SPPVSPSATP 691 Query: 707 PRYCS-GLGAGTAQ-DPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHE--RLLPQGP 762 P L A Q P P + P + + P +AA + P P Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA------PPPLAAPPLQVPPSPPASP 745 Query: 763 PELPSESPPPELPPPEAAPPV----LPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLA 818 P PS +PPP +PP AAPP+ P +SL P KP Q +L + L Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASL-PMSPLAKPPPQAPPALATPPLQALPSPP 804 Query: 819 TALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLP--------RGPRWAHGPGHR 870 + G A + ++ L P P+ A + P + PR PG Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-- 862 Query: 871 HLPYWRQKGP-------TRPKPKILRGQGESCRAGDLQGLSRGTARRARPL------PPD 917 P GP P P R + DL G S L P Sbjct: 863 --PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920 Query: 918 APPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLP 962 A PP +L + P+ + PA P LA G +PLP Sbjct: 921 GAAASPP-----PDAELAACHPAAWSRGPAPP-LAFRGAPGAPLP 959 Score = 63.5 bits (153), Expect = 1e-09 Identities = 151/606 (24%), Positives = 192/606 (31%), Gaps = 127/606 (20%) Query: 110 PCPLRGLLSCLPDGPTSQPHLATTPTDSS--CSSGPTGDGVQGSPL-PIKTADKPWPTRK 166 PCPL+ S L P P TP + + P G+ PL P+ T P Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 167 EGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHP 226 P L PSPP P +SP +P N L L+ P P Sbjct: 626 ALP-PLQAPPSPPASPP-----------------LSPLATPSPQAPNALAVHLLQAPFSP 667 Query: 227 ETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRH 286 SP P P SPP + P A Sbjct: 668 PPSPPVQAPFSP------------PASPPVS----------------------PSATPPS 693 Query: 287 PSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPH--PDLGAGGLLSVKMENSWVQSPPGP 344 +P + LQ P P TPPP P L A L Q PP P Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPS--ATPPPQAPPPLAAPPL----------QVPPSP 741 Query: 345 ASCQPGRQPLSPSATGDTRGVPQPSWGP-EAQAASASSSPLEALEACLKGIPPNGSSP-- 401 P P+SPSAT R P + P + + +S P+ L PP ++P Sbjct: 742 ----PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPL 797 Query: 402 SQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPL--AP 459 LP S Q S S + P + +A PVL L P+ P AP Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPSPPASPTLQAP 855 Query: 460 RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAW 519 R PT +S + P PG PP SP L P L Sbjct: 856 RRPPTPGPDTSVS-------GPRLTLALAPGPPPPPSRSPSSTLSG-------PDLAGH- 900 Query: 520 PCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCV 579 SS+A P E R + + EG G +P P ++C Sbjct: 901 --SSSATSTPE--ELRGYDSGPEG-------------GAAASPP-------PDAELAACH 936 Query: 580 PACHQRGFKDPGATR--PGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPS 637 PA RG P A R PG P + P + C G P A GPS Sbjct: 937 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 996 Query: 638 PSPSPGSSSSFSGSEGEDPRPEPDLWKPLP----QERDRLPSCKPPVPLSPCPGGTPAGS 693 P S G +++ +G+ P+ LP Q + L+ G AG Sbjct: 997 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA--AGG 1054 Query: 694 SGGSPG 699 SGG PG Sbjct: 1055 SGGGPG 1060 Score = 55.1 bits (131), Expect = 3e-07 Identities = 204/834 (24%), Positives = 273/834 (32%), Gaps = 154/834 (18%) Query: 221 PGPRHPETSPSFLPPLPSLGTS-RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKEL 279 PG P S PP P + R+ A G P A + + G + Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG-----------ATI 70 Query: 280 PEAQDRH-PSPS-GVGNRRLQENPGAWKRGSGGPGYLLTPP--------------PHPDL 323 PE+ R P+ S G +R P A RG P T P P P L Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP-L 129 Query: 324 GAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSP 383 G GL + E + + G A+ P R LS A DT G P P A A + ++ Sbjct: 130 GQKGL-RISAEETVAR---GKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAG 184 Query: 384 LEALEACLKGIPPNGSSPSQLPPT--------SCSQNP--QPGDSRSQKPE----LQPHR 429 E G+P S PPT S S++ +P + ++P LQ Sbjct: 185 TEV------GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238 Query: 430 SHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHP 489 S S ++ P L S R GPS RGTP + + S P G Q P Sbjct: 239 SRSLSSSATP-----LSSPARSGPSA----RGTPRAPAHPSQP-------KPKGLQALRP 282 Query: 490 GKGSPP--GSSPLQG-LENCLKEIPVPV---LRPAWPCSSAADRGPRRAEPRNWTADKEG 543 + +PP ++P G L + P P RP P +AA P P A Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342 Query: 544 LRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPE 603 L + AP L SP S P P P + +P Sbjct: 343 LAPPS----------PSAPPSLQTLPSPPATPPSQAPP----SMTTPPMQAPPSLQTIPP 388 Query: 604 GSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLW 663 P L++ P PL + + + SP ++ S + + L Sbjct: 389 IQVPHSLTSPSLQA------PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442 Query: 664 KPLPQERDRLPSCKPPVPLSPCPGGTPAG-------SSGGSPGEDPRRTEP-RYCSGLGA 715 P R S P P P PA S SP P P + S L + Sbjct: 443 SP-----SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497 Query: 716 GTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPE-LPSESPPPEL 774 + Q P+S L P +++S + +T L P E LPS +PPP Sbjct: 498 HSPQ--APLSSLIMPPLETQSSLAPP--------SLQTPPASLTTPPLENLPSLAPPPL- 546 Query: 775 PPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQ 834 A+ P+ PPC PLQ L E +AT +A+ Q Sbjct: 547 --QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604 Query: 835 VNRLGRRPQGP--GPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQG 892 L P P P QA LP P L P P + Sbjct: 605 --GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH--- 659 Query: 893 ESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPP--AHPL 950 +A PP +PP + P +S S+TP A P A PL Sbjct: 660 ---------------LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704 Query: 951 LAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSS 1004 SP P+ P+A P A PP A+ VP S P P P PS+ Sbjct: 705 QVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQVPPS---PPASP--PMSPSA 751 Score = 54.3 bits (129), Expect = 6e-07 Identities = 106/442 (23%), Positives = 146/442 (33%), Gaps = 83/442 (18%) Query: 588 KDPGATRPGVWRWLPEGSAPKPSPLHCLESALR-----GILPVRPL--RFACVGG---PS 637 + P A PG+ P GS P P+ +ALR G + +PL R +GG P Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPV--TPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 638 PSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSG-- 695 +P G + S +G+ +P P P +R P K SP P +P +SG Sbjct: 73 SAPRAGPTRS-AGTSSRNPASRP----PASGRGERAPPAKNT---SPGPVSSPGRASGTT 124 Query: 696 --GSPGEDPRR------------TEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLE 741 G G+ R TE S L AG +D + P ++ SR Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 742 LGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQ 801 G PR A R +GP + S + P PA+ +P G Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS------PAARRRPSAGGG----- 233 Query: 802 ELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGP 861 L + L AT L+ A+ GP G PR P Sbjct: 234 ----LQRPASRSLSSSATPLSSPARS----------------GPSARGT-------PRAP 266 Query: 862 RWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPA 921 P + L R T P+ G + GT +ARP+PP A Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT--KARPVPPPDNAA 324 Query: 922 EPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASA 981 P S L + P +P A P L P PP P + + P A Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSL-----QTLPSPPATPPSQAPPSMTTPPMQA 379 Query: 982 DADVPTSGVAPDGIPERPKEPS 1003 + T + P +P PS Sbjct: 380 PPSLQT--IPPIQVPHSLTSPS 399 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 78.2 bits (191), Expect = 4e-14 Identities = 202/802 (25%), Positives = 265/802 (33%), Gaps = 123/802 (15%) Query: 226 PETSPSFLPP--LPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQ 283 PE SP PP P+ +R P P + EA+ PL+ L PE Sbjct: 444 PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEE--SPLSPPPEES 501 Query: 284 DRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTP-PPHPDLGAGGLLSVKMENSWVQSPP 342 P P L+E+P + S L TP P P+ LS E S + PP Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP---LSPPFEESPLSPPP 558 Query: 343 G--PASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 P S P LSP P P P + AS E+ L PP S Sbjct: 559 EELPTSPPPEASRLSPPPEESPMS-PPPEESPMSPPPEASRLFPPFEESPLS--PPPEES 615 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPL--GLQSCVRDGPSRPLA 458 P PP + +P P DS P + S E +R LP+ L + P P Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP-P 674 Query: 459 PRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKE---IPVPVL 515 P +PTS +S SP + SPP L L L+E +P+P Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPT-SPPPEDSPASPPPEDSLMSLP--LEESPLLPLPEE 731 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFT 575 P S PR EP +E + E L SPQ Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL---------------SPQP-E 775 Query: 576 SSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGG 635 C+ A + P A P + +P+P LH L P Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHL--------SPQPEELHLSPQTEEPHLSPVPEE------ 821 Query: 636 PSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSG 695 P SP P S P+ E P P+E P + P PLSP P P Sbjct: 822 PCLSPQPEESHL-------SPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKPPE---- 869 Query: 696 GSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHE 755 PG+ P E G + +S L P +SE G P ++ E Sbjct: 870 -EPGQCPAPEELPLFPPPGEPS------LSPLLGEPALSEP--------GEPPLSPLPEE 914 Query: 756 -RLLPQGPPEL-PSESPPPELPPP------EAAPPVL-PASSLQPPCHCGKPLQQELHSL 806 L P G P L P PP LPPP AAPP L P L+ P E Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE---- 970 Query: 807 GAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHG 866 + LA + L T ++ + T V + P P+G AS + P P+ + Sbjct: 971 -SPLAAPI--LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPL 1027 Query: 867 PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGL 926 H +P P L G + G+S + L Sbjct: 1028 LQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVS-----------------DEAEL 1070 Query: 927 HCSSSQQLLSSTPSCHAAPPA--HPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADAD 984 H ++++ S P C A P+ PL + G P P PA G A Sbjct: 1071 HEMETEKV--SEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTA----- 1123 Query: 985 VPTSGV-APDGIPERPKEPSSL 1005 P G+ AP PE + P SL Sbjct: 1124 -PLDGIDAPGSQPEPGQTPGSL 1144 Score = 69.7 bits (169), Expect = 1e-11 Identities = 186/764 (24%), Positives = 239/764 (31%), Gaps = 147/764 (19%) Query: 87 ESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGD 146 + E++ G + P+ A PL + LP P + L+ P +S S P Sbjct: 413 QCEAKPLGKAGVQLEPQLEA-----PLNEEMPLLP--PPEESPLSPPPEESPTSPPPEAS 465 Query: 147 GVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNS 206 + P + + P P PP SP P +S Sbjct: 466 RLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESP---------------LSPPPESS 510 Query: 207 PLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGD 266 P P P + P PP P+L T + P SPP+ Sbjct: 511 PFS-----------PLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP------ 553 Query: 267 CPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAG 326 L PE P P RL P ++PPP Sbjct: 554 ---------LSPPPEELPTSPPPEA---SRLSPPPEESPMSPPPEESPMSPPPE-----A 596 Query: 327 GLLSVKMENSWVQSPP--GPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPL 384 L E S + PP P S P LSP D+ P P P + S L Sbjct: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE-DSPMSPPPEESPMSPPPEVSR--L 653 Query: 385 EALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSR-SQKPELQPHRSHSEEATREPVLPL 443 L + PP SP PP +P P SR S PE P E++ P Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713 Query: 444 GLQSC-VRDGPSRPL--APRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPL 500 L S + + P PL P+ P S S + SP + + P SP Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP- 772 Query: 501 QGLENCLKEIP-VPVLRP------AWPCSSAADRGPRRAEPRNWTADKEGLRAEACESAR 553 Q E CL +P P L P P P+ EP +E + E + Sbjct: 773 QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH 832 Query: 554 LGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLH 613 L +P +SP+ S P K P + RP P G P P L Sbjct: 833 L------SPQSEEPCLSPRPEESHLSPELE----KPPLSPRPEKPPEEP-GQCPAPEEL- 880 Query: 614 CLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRL 673 PL F G PS SP G + GE P PLP+E Sbjct: 881 -------------PL-FPPPGEPSLSPLLGEPA--LSEPGEPP------LSPLPEELPLS 918 Query: 674 PSCKP------------PVPLSP----------CPGGT---PAGSSGGSPGEDPRRTE-- 706 PS +P P PLSP P G P G+ G S E P Sbjct: 919 PSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPIL 978 Query: 707 PRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELP 766 S DP PV P + S G +G P + E L PQ P L Sbjct: 979 ETPISPPPEANCTDPEPVP-----PMILPPSPGSPVGPASPILM----EPLPPQCSPLLQ 1029 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPL----QQELHSL 806 P PP + +PP LP S P GK + + ELH + Sbjct: 1030 HSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEM 1073 Score = 68.2 bits (165), Expect = 4e-11 Identities = 160/671 (23%), Positives = 215/671 (32%), Gaps = 132/671 (19%) Query: 342 PGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSP 401 PGP C+ +PL + P+ +A PL +PP SP Sbjct: 409 PGPLQCEA--KPLGKAGV---------QLEPQLEAPLNEEMPL---------LPPPEESP 448 Query: 402 SQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRG 461 PP +P P SR P + S EA L L + + P P P Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEA-------LHLSRPLEESPLSP-PPEE 500 Query: 462 TPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS-------PPGSSPLQGLENCLKEIPVPV 514 +P S SS L+ SP+ + P + PP +SPL P P Sbjct: 501 SPLSPPPESSPFSPLE-ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE 559 Query: 515 LRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVF 574 P P A+ P E +E + E++RL E+P +SP Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP------LSPPPE 613 Query: 575 TSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVG 634 S P P PE S P P S + + PL Sbjct: 614 ESPLSPPPEASRLSPP-----------PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662 Query: 635 GPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSS 694 P P SP S P PE P P E RL P SP P +PA Sbjct: 663 SPPPEESPLS-----------PPPEESPTSP-PPEASRLSPPPEDSPTSPPPEDSPASP- 709 Query: 695 GGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTH 754 P ED + P + P+ L + P++ S G L PR Sbjct: 710 ---PPEDSLMSLPL-----------EESPLLPLPEEPQLCPRSEGPHLS---PR------ 746 Query: 755 ERLLPQGPPELPSESPPPELP--PPEAAPPVLPASSLQPPCHCGKPLQQEL--HSLGAAL 810 PE P SP PE P P+A P L + PC C P + L + G L Sbjct: 747 --------PEEPHLSPRPEEPHLSPQAEEPHLSPQP-EEPCLCAVPEEPHLSPQAEGPHL 797 Query: 811 AEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGP--GPMGQASWMWTLPRGPRWAHGPG 868 + + + L + +T+ L P+ P P + S + P + P Sbjct: 798 SPQPEELHLS----------PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847 Query: 869 HRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHC 928 HL +K P P+P+ + C A + LP PP EP Sbjct: 848 ESHLSPELEKPPLSPRPEKPPEEPGQCPAPE-------------ELPLFPPPGEP----- 889 Query: 929 SSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTS 988 S S L S PP PL S P L P +P PP + Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP 949 Query: 989 GVAPDGIPERP 999 ++P G E P Sbjct: 950 ALSPLGELEYP 960 Score = 47.8 bits (112), Expect = 5e-05 Identities = 74/303 (24%), Positives = 101/303 (33%), Gaps = 45/303 (14%) Query: 734 SEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPAS-SLQPP 792 SEA+ G G P T E + + PS S +L + P P+S LQPP Sbjct: 4035 SEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPP 4094 Query: 793 CHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVN-RLGRRPQGPGPMGQA 851 QQ++ L A +L + + A V + Q + LG +P G Sbjct: 4095 LRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQP------GSM 4148 Query: 852 SWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARR- 910 + P+ P + P + GP + L G G G L+ +G + Sbjct: 4149 TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN 4208 Query: 911 --ARPLPPD----------------------APPAEPPGLHCSSSQQLLSSTPSC--HAA 944 R L P PP + PG S Q LL P Sbjct: 4209 PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPG 4268 Query: 945 PPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADV--PTSGVAPDGIPERPKEP 1002 P PL G + PP +PA PP A + V P P P+ PK P Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPA--------PPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320 Query: 1003 SSL 1005 S L Sbjct: 4321 SQL 4323 Score = 39.7 bits (91), Expect = 0.015 Identities = 145/619 (23%), Positives = 199/619 (32%), Gaps = 140/619 (22%) Query: 375 QAASASSSPLEALEACLKGIP--PNGSSPSQ----LPPTSCSQNPQ-PGDSRSQKPELQP 427 Q + S P A G P P G S S PP P PG+ + P P Sbjct: 2109 QPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVP 2168 Query: 428 HRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQ 487 + S++ P GL P P AP P S + + G+ Sbjct: 2169 AQVPSQD-------PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221 Query: 488 HPGK--GSPPGSSPLQGLENCLKEIPVPVLRPAWPC-------SSAADRGPRRAEP---- 534 PG+ +PPG+ Q P P L+P P S G + +EP Sbjct: 2222 QPGEFHTTPPGTPRHQ------PSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP 2275 Query: 535 -------RNWTADKEGLRAEACESARLGQGRGEAPTRSLHL-----VSPQVFTSSCVPAC 582 + KE L A + G ++P+ HL +P VF + P Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335 Query: 583 HQRGFKDPG-ATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPS 641 Q + PG RP + P A PSP P P F Sbjct: 2336 SQVEPQSPGLGLRP---QEPPPAQALAPSP------------PSHPDIFR---------- 2370 Query: 642 PGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCK-PPVPLSPCPGGTPAGSSGGSPGE 700 PGS + PRP+P P P+ LP P P S P + SS SP Sbjct: 2371 PGSYTDPYAQPPLTPRPQP----PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426 Query: 701 DPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQ 760 + +C Q P P S+ RP+ + L H PR PQ Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL---HKPPR----------PQ 2473 Query: 761 GPPELPSESP------------PPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGA 808 PPE+ ++ P LP A S QPP P GA Sbjct: 2474 -PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP------GTGA 2526 Query: 809 ALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQ-------GPGP-MGQASWMWTLPRG 860 + T + + +++ V + G P GPGP +G+ P+ Sbjct: 2527 FVGTPSPMRFTFPQAVGE--PSLKPPVPQPGLPPPHGINSHFGPGPTLGK-------PQS 2577 Query: 861 PRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPP 920 + G+ H P GP+ S G+ GLS R LPP AP Sbjct: 2578 TNYTVATGNFH-PSGSPLGPS------------SGSTGESYGLS--PLRPPSVLPPPAPD 2622 Query: 921 AEPPGLHCSSSQQLLSSTP 939 P L +SQ+ ++P Sbjct: 2623 GSLPYLSHGASQRSGITSP 2641 Score = 38.5 bits (88), Expect = 0.033 Identities = 116/442 (26%), Positives = 148/442 (33%), Gaps = 89/442 (20%) Query: 85 SPESESRGASLDGERA--SPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSG 142 SPE E S E+ P A E PL P G S L P S Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP-----PPGEPSLSPLLGEPALSEPGEP 906 Query: 143 PTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSP------SRRKSHRGQ-ERG 195 P SPLP + P P + +P PP SP S G+ E Sbjct: 907 PL------SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960 Query: 196 TSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPL---PSLGTSRLTRADLGPG 252 G S SPL I L+ + P P T P +PP+ PS G+ +GP Sbjct: 961 FGAKGDSDPESPLAAPI--LETPISPPPEANCTDPEPVPPMILPPSPGSP------VGPA 1012 Query: 253 SPPWAVKTEAVSGDC-PLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGP 311 SP + E + C PL L H L Q+ PS P Sbjct: 1013 SP---ILMEPLPPQCSPL--LQHSLVP----QNSPPSQCS-------------------P 1044 Query: 312 GYLLTPPPHPDLGAGGLLSV-------KMENSWVQSPPGPASCQPGRQPLSPSATGDTRG 364 L P P G ++ V +ME V P PA PL PS GD Sbjct: 1045 PALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL-PSPMGDL-S 1102 Query: 365 VPQPSWGPEAQAASA---SSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQ 421 P PS P S ++PL+ ++A P + P Q P + S+ G Sbjct: 1103 CPAPSPAPALDDFSGLGEDTAPLDGIDA-----PGSQPEPGQTPGSLASE--LKGSPVLL 1155 Query: 422 KPE-LQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGS 480 PE L P + G ++ P P+AP TP + S D + Sbjct: 1156 DPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP--TPPTLIKS-------DIVN 1206 Query: 481 PVGNQGQHPGKGSPPGSSPLQG 502 + N Q S PGS PL G Sbjct: 1207 EISNLSQGDASASFPGSEPLLG 1228 Score = 37.7 bits (86), Expect = 0.056 Identities = 102/427 (23%), Positives = 138/427 (32%), Gaps = 89/427 (20%) Query: 167 EGPGALGGEPSPPTHSPSR-RKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRH 225 E PG GG+ S P SP +S + E E G S Sbjct: 2259 ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGAS----------------------- 2295 Query: 226 PETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDR 285 SPS+ PP S + LG +KT V PL P A Sbjct: 2296 ---SPSYGPPNLGFVDSPSSGTHLG----GLELKTPDVF-KAPL---------TPRASQV 2338 Query: 286 HPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWV---QSPP 342 P G+G R QE P A +PP HPD+ G + + PP Sbjct: 2339 EPQSPGLG-LRPQEPPPA-------QALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390 Query: 343 GPASC---QPGRQPLSPSATGDTRGVPQPSWGPEAQAASAS---SSPLEALEACLKGIPP 396 P SC P P P + VP P++Q++S S PL A C + P Sbjct: 2391 PPESCCALPPRSLPSDPFSR-----VPA---SPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442 Query: 397 NGSSPSQLP-PTSCSQNPQPGDSRSQKPELQPHR--SHSEEATREPVLPLGLQSCVRDGP 453 SP P S Q+ P + P QP + + G + + GP Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502 Query: 454 SRPL---APRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEI 510 + L P G P +F S T G+P + P P P + Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGT--GAFVGTPSPMRFTFPQAVGEPSLKP---------PV 2551 Query: 511 PVPVLRPAWPCSSAADRGPRRAEPR--NWTADKEGLRAEAC----ESARLGQGRGEAPTR 564 P P L P +S GP +P+ N+T S G+ G +P R Sbjct: 2552 PQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLR 2611 Query: 565 SLHLVSP 571 ++ P Sbjct: 2612 PPSVLPP 2618 Score = 37.7 bits (86), Expect = 0.056 Identities = 79/326 (24%), Positives = 110/326 (33%), Gaps = 56/326 (17%) Query: 221 PGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELP 280 PGP PE P PP RL A + P P + C ++ P Sbjct: 3091 PGPLGPEERP---PPAADASEPRL--ASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAP 3145 Query: 281 EAQDR----HPSPSGVGNRRLQENPGAWKRGS------------GGPGYLLTPPPHPDLG 324 A P S +G+R + G + G P +LLTP P G Sbjct: 3146 AANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPG 3205 Query: 325 AGGLL-SVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSP 383 LL ++E+ + P GPA A+GD + S AS P Sbjct: 3206 GSSLLEKFELESGALTLPGGPA------------ASGDELDKMESS-------LVASELP 3246 Query: 384 L---EALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKP-----ELQPHRSHSEE- 434 L + LE K + +QL P Q Q S P PH S Sbjct: 3247 LLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSL 3306 Query: 435 ATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGN--QGQHPGKG 492 A + L LGL + G +PL P P + + + S G+ GQH G+ Sbjct: 3307 AGSQQQLSLGLAGARQPGLPQPLMPT-QPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQA 3365 Query: 493 SPPGSSPLQGLENCLKEIPVPVLRPA 518 G P Q + L + P+ + P+ Sbjct: 3366 ---GLVPQQSSQPVLSQKPMGTMPPS 3388 Score = 36.6 bits (83), Expect = 0.13 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 18/93 (19%) Query: 719 QDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSE-SPPPE---- 773 ++P P+ Q E +P G++L P++ A +E + P PP S SPPPE Sbjct: 407 KEPGPL-QCEAKPL---GKAGVQL---EPQLEAPLNEEM-PLLPPPEESPLSPPPEESPT 458 Query: 774 LPPPEAA-----PPVLPASSLQPPCHCGKPLQQ 801 PPPEA+ P LPAS L H +PL++ Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEE 491 Score = 36.6 bits (83), Expect = 0.13 Identities = 66/253 (26%), Positives = 87/253 (34%), Gaps = 70/253 (27%) Query: 176 PSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPP 235 P PP P + +G GI P L+ L+ +L P+ SP Sbjct: 4170 PQPPKPGPVLQSG-----QGLPGVGIMPTVGQLRAQ---LQGVLAKNPQLRHLSPQQQQQ 4221 Query: 236 LPSLGTSR-LTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGN 294 L +L R L ++ +PP+ E + PLQGLL C +L P Sbjct: 4222 LQALLMQRQLQQSQAVRQTPPYQ---EPGTQTSPLQGLLGCQPQLGGFPGPQTGP----- 4273 Query: 295 RRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPL 354 LQE GA R G PP P +PPG S P P+ Sbjct: 4274 --LQEL-GAGPRPQG-------PPRLP------------------APPGALSTGPVLGPV 4305 Query: 355 SPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQ 414 P+ P PS E + S SP L + +QLPPT Sbjct: 4306 HPT--------PPPSSPQEPKRPSQLPSPSSQLP-----------TEAQLPPT------H 4340 Query: 415 PGDSRSQKPELQP 427 PG + Q P L+P Sbjct: 4341 PGTPKPQGPTLEP 4353 Score = 35.8 bits (81), Expect = 0.21 Identities = 178/803 (22%), Positives = 248/803 (30%), Gaps = 140/803 (17%) Query: 28 PGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGAMDSPE 87 PG GG + +P G P G L + +L K + L K + S Sbjct: 1844 PGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSER 1903 Query: 88 SESRGAS---LDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPT 144 + G L+G R + + PL L S P S P L +P S G Sbjct: 1904 EQHLGCGTPGLEGSRTPLQRPFLQGGLPLGNLPSSSP--MDSYPGLCQSPFLDSRERGGF 1961 Query: 145 GDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPG 204 G P D PW G+ G PS PT + + G+S Sbjct: 1962 FSPEPGEP------DSPWT------GSGGTTPSTPTTPTTEGEGD----------GLSYN 1999 Query: 205 NSPLQ--------GLINCLKEILVPGPRHPETSPSFLPPLPSLGTS--RLTRADLGPGSP 254 LQ G ++ + +L P + P S +L R Sbjct: 2000 QRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDY-PDWSSRCKQIMKLWRKVPAADKA 2058 Query: 255 PWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYL 314 P+ K + D ++ +++ E+Q + G R+ + P R PG L Sbjct: 2059 PYLQKAK----DNRAAHRINKVQKQAESQINKQTKVGDIARKT-DRPALHLRIPPQPGAL 2113 Query: 315 LTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPS----- 369 +PPP ++ SP PA G G P Sbjct: 2114 GSPPP-----------AAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLK 2162 Query: 370 WGPEAQAASASSSPLEA-----LEACLKGIPPN-------GSSPSQLPPTSCSQNP---Q 414 P+ A S P LE PP +P+Q P S P Q Sbjct: 2163 LPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQ 2222 Query: 415 PGDSRSQKPELQPHRSHSEEATREPVLP----LGLQSCVRDGPSRPLAPRGTPTSFSSSS 470 PG+ + P H+ + + +P P L + G + P +P F S Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESR 2282 Query: 471 ST----DWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAAD 526 +L SP SP + L GLE + P P P +S Sbjct: 2283 KALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE---LKTPDVFKAPLTPRAS--- 2336 Query: 527 RGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRG 586 + EP++ GLR + A+ AP+ H P +F Sbjct: 2337 ----QVEPQS---PGLGLRPQEPPPAQ-----ALAPSPPSH---PDIFRPG--------S 2373 Query: 587 FKDPGATRPGVWRWLPEGSAPKPS-----PLHCLESALRGILPVRPLRFACVGGPSPSPS 641 + DP A P P P P P L S +P P + P +P Sbjct: 2374 YTDPYAQPP----LTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPL-TPR 2428 Query: 642 PGSSSSFSGSEGEDPRPEPDLWK---PLPQERDRL-PSCKPPVPLSP---CPGGTPAGSS 694 P S+ +F S PD + PQ RD P KPP P P G+ A +S Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS 2488 Query: 695 GGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTH 754 G+ G P AG P Q P S G G P T Sbjct: 2489 LGAGGF------PAALPAGPAGELHAKVPSGQ----PPNFVRSPGTGAFVGTPSPMRFTF 2538 Query: 755 ERLLPQGPPELPSESPPPELPPP 777 + + G P L P P LPPP Sbjct: 2539 PQAV--GEPSLKPPVPQPGLPPP 2559 Score = 35.4 bits (80), Expect = 0.28 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 27/89 (30%) Query: 759 PQGPPELPSE---------------SPPPELPPPEAAPPVLPASSLQ-------PPCHCG 796 PQGPP LP+ +PPP P P LP+ S Q PP H G Sbjct: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPG 4342 Query: 797 KPLQQELHSLGAALAEKLDRLATALAGLA 825 P Q G L R++ A A LA Sbjct: 4343 TPKPQ-----GPTLEPPPGRVSPAAAQLA 4366 Score = 33.5 bits (75), Expect = 1.1 Identities = 66/293 (22%), Positives = 93/293 (31%), Gaps = 71/293 (24%) Query: 169 PGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPET 228 PG+ G EPS P +S G +P G ++ Sbjct: 2717 PGSWGAEPSSPAFEQ-----------------LSRGQTPFAGT-------------QDKS 2746 Query: 229 SPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPS 288 S LPP S+L+ LGPGS P S D + P A PS Sbjct: 2747 SLVGLPP------SKLSGPILGPGSFP--------SDD-------RLSRPPPPAT---PS 2782 Query: 289 PSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQ 348 V +R+L A+ + + PG L L + + S P++ Sbjct: 2783 SMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG 2842 Query: 349 P--GRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPP 406 P GRQ L G + +P P G + + +E KG+ P G+ Sbjct: 2843 PELGRQALGSPLAGISTRLPGP--GEPVPGPAGPAQFIELRHNVQKGLGPGGT------- 2893 Query: 407 TSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP 459 P PG Q+P P E + L + PS P AP Sbjct: 2894 ------PFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAP 2940 Score = 32.7 bits (73), Expect = 1.8 Identities = 45/153 (29%), Positives = 56/153 (36%), Gaps = 32/153 (20%) Query: 644 SSSSFSGSEGEDPRPEPDLWK-----PLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSP 698 +S F+ S P P+L + PL RLP P P PG PAG + Sbjct: 2827 TSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPG-----PGEPVPG--PAGPA---- 2875 Query: 699 GEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLL 758 + E R+ G G P P +RPR S R+A + L Sbjct: 2876 ----QFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPH------RLAPEGLRGLA 2925 Query: 759 PQG-PPELPSESPPPEL-----PPPEAAPPVLP 785 G PP+ PS P PEL P P P LP Sbjct: 2926 VSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958 Score = 30.8 bits (68), Expect = 6.9 Identities = 37/146 (25%), Positives = 53/146 (36%), Gaps = 11/146 (7%) Query: 660 PDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQ 719 P+ ++ L E +P + PGG G G SP P + ++ + L T + Sbjct: 4812 PNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLK-QFDAVLPGYTLK 4870 Query: 720 DPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEA 779 + L K+ + H + R L PPE PS P P P P A Sbjct: 4871 SQLDILSLLKQESPAPEP---PTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP-A 4926 Query: 780 APPVLPASSL------QPPCHCGKPL 799 +PP P L +PP PL Sbjct: 4927 SPPTEPLVELPTEPLAEPPVPSPLPL 4952 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 73.6 bits (179), Expect = 9e-13 Identities = 174/724 (24%), Positives = 236/724 (32%), Gaps = 91/724 (12%) Query: 1 MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLH 60 +R + E V+ G A P + LS G G P G P R S Sbjct: 134 LRISAEETVARGKATEAPKRSALS--------AGARRDTSGPTP---GTPSPAMARRSRA 182 Query: 61 LTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCL 120 V L + P + + P AS + P AA R P GL Sbjct: 183 AGTEVGLPRPAPS---ARPRPPTEGPRKSVSSAS-EHSTTEPSPAARRRPSAGGGL---- 234 Query: 121 PDGPTSQP-HLATTPTDSSCSSGPTGDGVQGSP----------LPIKTADKPWPTRKEGP 169 P S+ + TP S SGP+ G +P L + P RK+ Sbjct: 235 -QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 170 GALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVP-GPRHPET 228 ALG S P +PS + + Q T A +P + C +P P P Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPA------TPHSSSLTCQLATPLPLAPPSPSA 347 Query: 229 SPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPS 288 PS L LPS + ++A GSP T + PL L + P A P Sbjct: 348 PPS-LQTLPSPPATPPSQATTSLGSPTLQA-THSFLPSPPLSPLATPPPQAPPALALPP- 404 Query: 289 PSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGP---- 344 LQ P P L TP P A L+V + + PP P Sbjct: 405 --------LQAPPSPPASPPLSP--LATPSPQ----APNALAVHLLQAPFSPPPSPPVQA 450 Query: 345 ASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQL 404 P P+SPSAT ++ P + P S +SP + A PP P Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT---PPPQAPPPLAA 507 Query: 405 PPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPT 464 PP ++ P P LQ A P Q+ S P++P TP Sbjct: 508 PPLQLAKPPPQAPPALATPPLQ--------ALPSPPASFPGQAPFSPSASLPMSPLATPP 559 Query: 465 SFSSS--SSTDWDLDFGSPVGNQGQHPGKGSPPG-SSPLQGLENCLKEIPVPVLRPAWPC 521 + ++ + P Q P + PG + + G L P P P+ Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619 Query: 522 SSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPA 581 SS + T+ E LR +S G P P ++C PA Sbjct: 620 SSTLSGPDLAGHSSSATSTPEELR--GYDSGPEGGAAASPP--------PDAELAACHPA 669 Query: 582 CHQRGFKDPGATR--PGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPS 639 RG P A R PG P + P + C G P A GPSP Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729 Query: 640 PSPGSSSSFSGSEGEDPRPEPDLWKPLP----QERDRLPSCKPPVPLSPCPGGTPAGSSG 695 S G +++ +G+ P+ LP Q + L+ G AG SG Sbjct: 730 TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA--AGGSG 787 Query: 696 GSPG 699 G PG Sbjct: 788 GGPG 791 Score = 63.2 bits (152), Expect = 1e-09 Identities = 198/803 (24%), Positives = 252/803 (31%), Gaps = 195/803 (24%) Query: 221 PGPRHPETSPSFLPPLPSLGTS-RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKEL 279 PG P S PP P + R+ A G P A + + G + Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG-----------ATI 70 Query: 280 PEAQDRH-PSPS-GVGNRRLQENPGAWKRGSGGPGYLLTPP--------------PHPDL 323 PE+ R P+ S G +R P A RG P T P P P L Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP-L 129 Query: 324 GAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSP 383 G GL + E + + G A+ P R LS A DT G P P A A + ++ Sbjct: 130 GQKGL-RISAEETVAR---GKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAG 184 Query: 384 LEALEACLKGIPPNGSSPSQLPPT--------SCSQNP--QPGDSRSQKPE----LQPHR 429 E G+P S PPT S S++ +P + ++P LQ Sbjct: 185 TEV------GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238 Query: 430 SHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHP 489 S S ++ P L S R GPS RGTP + + S P G Q P Sbjct: 239 SRSLSSSATP-----LSSPARSGPSA----RGTPRAPAHPSQP-------KPKGLQALRP 282 Query: 490 GKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEAC 549 + +PP L P+ P+ P ++ + P T L + Sbjct: 283 PQVTPPRKDAAPALGPLSSS---PLATPS-PSAALQSQAPPTLPA---TPHSSSLTCQLA 335 Query: 550 ESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKP 609 L AP L SP S Q T +LP +P Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPS------QATTSLGSPTLQATHSFLP---SPPL 386 Query: 610 SPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQE 669 SPL L + PL+ PSP SP S + P P L Sbjct: 387 SPLATPPPQAPPALALPPLQ----APPSPPASPPLSPLAT--------PSPQAPNALAVH 434 Query: 670 RDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEK 729 + P PP P P PA SP P T P A P Q+ Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPA-----SPPVSPSATPPSQAPPSLAA------PPLQVPP 483 Query: 730 RPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPAS-- 787 P P PP PS +PPP+ PPP AAPP+ A Sbjct: 484 SP---------------------------PASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516 Query: 788 SLQPPCHCGKPLQ-----------QELHSLGAALAEKLDRLATALAGLAQEVATMRTQVN 836 PP PLQ Q S A+L + LAT +A QV Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPLLQVP 574 Query: 837 ---------RLGRRPQGPGPMGQASWMWTLPRGPR--WAHGPGHRHLPYWRQKGPTRPKP 885 + RRP PGP S GPR A PG P P Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVS-------GPRLTLALAPG--------------PPP 613 Query: 886 KILRGQGESCRAGDLQGLSRGTARRARPL------PPDAPPAEPPGLHCSSSQQLLSSTP 939 R + DL G S L P A PP +L + P Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP-----PDAELAACHP 668 Query: 940 SCHAAPPAHPLLAHTGGHQSPLP 962 + + PA P LA G +PLP Sbjct: 669 AAWSRGPAPP-LAFRGAPGAPLP 690 Score = 54.3 bits (129), Expect = 6e-07 Identities = 187/719 (26%), Positives = 243/719 (33%), Gaps = 141/719 (19%) Query: 321 PDLGAGGLLSVKMENSWVQSPP-GPASCQP-------GRQPLSPSATG-DTRGVPQ--PS 369 P A GLL+ + S PP PA+ + GR+PL+ A G +P+ P Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 370 WGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHR 429 GP A ++S +P PP + PP ++N PG P P R Sbjct: 77 AGPTRSAGTSSRNPASR--------PPASGRGERAPP---AKNTSPG------PVSSPGR 119 Query: 430 SHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHP 489 + T P PLG Q +R +A RG T S+ L G+ G P Sbjct: 120 A---SGTTRPG-PLG-QKGLRISAEETVA-RGKATEAPKRSA----LSAGARRDTSGPTP 169 Query: 490 GKGSPPGS--SPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAE 547 G SP + S G E L P P RP P GPR++ ++ E E Sbjct: 170 GTPSPAMARRSRAAGTEVGLPR-PAPSARPRPPTE-----GPRKSV----SSASEHSTTE 219 Query: 548 ACESAR----LGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPE 603 +AR G G +RSL +SS P G + G R Sbjct: 220 PSPAARRRPSAGGGLQRPASRSL--------SSSATPLSSPAR---SGPSARGTPRAPAH 268 Query: 604 GSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLW 663 S PKP L ALR P + A +P+ P SSS + P P L Sbjct: 269 PSQPKPKGLQ----ALRPPQVTPPRKDA-----APALGPLSSSPLA-----TPSPSAALQ 314 Query: 664 KPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCP 723 P P +P +P + P P + P L + A P Sbjct: 315 SQAP----------PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP-- 362 Query: 724 VSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPV 783 S+A+ L G P + A TH L PP P +PPP+ PP A PP+ Sbjct: 363 ----------SQATTSL----GSPTLQA-THSFL--PSPPLSPLATPPPQAPPALALPPL 405 Query: 784 LPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQ 843 PP P L L + + LA L A + + P Sbjct: 406 QA-----PP---SPPASPPLSPLATPSPQAPNALAVHLLQ-----APFSPPPSPPVQAPF 452 Query: 844 GPGPMGQASWMWTLP-RGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQ- 901 P S T P + P P + P P P A LQ Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 902 GLSRGTARRARPLPP----DAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGH 957 A A PP +PPA PG S L +P P A P+LA Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA----- 567 Query: 958 QSPL---PPLVPAALPLQG-ASPPAASADADVP----TSGVAPDGIPERPKEPSSLLGG 1008 +PL PP PA+ LQ PP D V T +AP P + PSS L G Sbjct: 568 -APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625 Score = 37.4 bits (85), Expect = 0.073 Identities = 87/347 (25%), Positives = 111/347 (31%), Gaps = 47/347 (13%) Query: 672 RLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRP 731 R P+ + P L+P P G+P P P LGA A P+++ Sbjct: 15 RTPAARAPGLLTPRPPGSP---------RPPPPVTPAALRVLGAAGAVGRKPLAER---- 61 Query: 732 RVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP 791 + G + PR + P P S E PP P SS P Sbjct: 62 --AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS--P 117 Query: 792 PCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRR-PQGPGPMGQ 850 G L G ++ + T G A E A R+ ++ RR GP P Sbjct: 118 GRASGTTRPGPLGQKGLRISAE----ETVARGKATE-APKRSALSAGARRDTSGPTPGTP 172 Query: 851 ASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARR 910 + M R G LP R RP+P + A + A R Sbjct: 173 SPAMARRSRAAGTEVG-----LP--RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225 Query: 911 ARPLPPDAPPAEPPGLHCSSSQQLLSST----PSCHAAP--PAHPLLAHTGGHQSPLPPL 964 RP P SSS LSS PS P PAHP G Q+ PP Sbjct: 226 RRP-SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284 Query: 965 V--------PAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 V PA PL +S P A+ AP +P P S Sbjct: 285 VTPPRKDAAPALGPL--SSSPLATPSPSAALQSQAPPTLPATPHSSS 329 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 72.4 bits (176), Expect = 2e-12 Identities = 216/932 (23%), Positives = 292/932 (31%), Gaps = 182/932 (19%) Query: 121 PDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPT 180 P G + +P + D+ P GVQG P P K + GP L G P Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP---- 484 Query: 181 HSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLG 240 G+ G G PG + G E PGP P+ SP G Sbjct: 485 ----------GERGGPGSRGF-PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533 Query: 241 TSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQEN 300 PGSP KT P QD P P G R Q Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPG---------------PAGQDGRPGPPGPPGARGQAG 578 Query: 301 ----PGAWKRGSGGPGYL---LTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQP 353 PG K +G PG P P +G G K + Q PPGPA R Sbjct: 579 VMGFPGP-KGAAGEPGKAGERGVPGPPGAVGPAG----KDGEAGAQGPPGPAGPAGERGE 633 Query: 354 LSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNP 413 P+ + +G+P P+ GP +A +G+P + +P P + + Sbjct: 634 QGPAGSPGFQGLPGPA-GPPGEAGKPGE----------QGVPGDLGAPG--PSGARGERG 680 Query: 414 QPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTD 473 PG+ Q GP P PRG Sbjct: 681 FPGERGVQ------------------------------GPPGPAGPRGAN---------- 700 Query: 474 WDLDFGSPVGNQGQHPGKGSP--PGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRR 531 G+P GN G G+P PGS GL+ E L P D GP+ Sbjct: 701 -----GAP-GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL--PGPKGDRGDAGPKG 752 Query: 532 AEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPG 591 A+ + K+G+R G G + S + A RG +PG Sbjct: 753 AD---GSPGKDGVRGLTGPIGPPGPA-GAPGDKGESGPSGPAGPTGARGAPGDRG--EPG 806 Query: 592 ATRPGVWRWLPEGSAPKPSPLHCLESALRGIL-PVRPLRFACVGGPSPSPSPGSSSSFSG 650 P + P + ++ +G P P GP+ P P + G Sbjct: 807 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP------AGPAGPPGPIGNVGAPG 860 Query: 651 SEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPR-RTEPRY 709 ++G P P R+ PP P P G +G G+ PR T P Sbjct: 861 AKGARGSAGPPGATGFPGAAGRV---GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG 917 Query: 710 CSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-----QGPPE 764 G G P P EK ++ G G +A + LP +G P Sbjct: 918 RPG-EVGPPGPPGPAG--EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974 Query: 765 LPSESPPPELPPPEAAP-------PVLPASSLQPPCHCGK---PLQQELHSLGAALAEKL 814 LP S P P A P+ P PP G+ P + + K Sbjct: 975 LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034 Query: 815 DRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMW----TLPRGPRWAHGPGHR 870 DR T AG P PGP+G A T P GP GP Sbjct: 1035 DRGETGPAGPPGAPGA-----------PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083 Query: 871 HLPYWRQKGPTRPKPKILRGQGESCRAGD--LQGLSRGTARRARPLPPDAPPAEPPGLHC 928 P GP P+ +GE+ GD ++G + + P PP +P + P Sbjct: 1084 RGP----AGPQGPR----GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS--- 1132 Query: 929 SSSQQLLSSTPSCHAAPPAH---PLLAHTGGHQSPLPPLVPA-----ALPLQGASPPAAS 980 +S P+ PP P G P+ P P A P+ PP Sbjct: 1133 ------GASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186 Query: 981 ADADVPTSGVAPDGIPERPKEPSSLLGGVQRA 1012 P++G +P+ P+E + G RA Sbjct: 1187 GPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRA 1218 Score = 31.2 bits (69), Expect = 5.3 Identities = 43/158 (27%), Positives = 50/158 (31%), Gaps = 23/158 (14%) Query: 24 SPSEPGRAVGGGSHADEGQE-PAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGA 82 +P PG G D G+ PAG P G + A + P GE Sbjct: 1050 APGAPGPVGPAGKSGDRGETGPAGPAGPVGP-------VGARGPAGPQGPRGDKGETGEQ 1102 Query: 83 MDSPESESRGAS-LDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSS 141 D RG S L G P + + P G P GP P A Sbjct: 1103 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG-----PAGPRGPPGSA---------G 1148 Query: 142 GPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP 179 P DG+ G P PI T GP G P PP Sbjct: 1149 APGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 70.1 bits (170), Expect = 1e-11 Identities = 220/964 (22%), Positives = 332/964 (34%), Gaps = 212/964 (21%) Query: 149 QGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPL 208 +G P P+K A +P + P AL G SP ++ RG + + G+ PG PL Sbjct: 192 RGGP-PVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKR-RRGCN--SEQTGLPPG-LPL 246 Query: 209 QGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS---RLTRADLGPG--SPPWAVKTEAV 263 P P P P PPLP L TS +LT+ L W + + Sbjct: 247 PP---------PPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERK-- 295 Query: 264 SGDCPLQ------GLLHCLKELPEAQDRHPSPSGVGNRRLQE---NPGAWKRGSGGPGYL 314 G P + L H A HP G+R + PG G+ G L Sbjct: 296 -GSAPPERQEQRHSLPHPYPYPAPAYTAHPP----GHRLVPAAPPGPGPRPPGAESHGCL 350 Query: 315 -LTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDT----------- 362 T PP DL + +M++S SP +C P P G T Sbjct: 351 PATRPPGSDLRESRVQRSRMDSS--VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNT 408 Query: 363 --RGV-PQPS----------------WGPEAQAASASSSPLEALEACLK--GIPPNGSSP 401 RGV P P G +A +S P A +PP SSP Sbjct: 409 GLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSP 468 Query: 402 SQLPPTSCSQ--NPQPGDSRSQKPELQPHRSHSEE------ATREPVLPLGLQSCVRDGP 453 PP C + P P + + P + R E T P P R+G Sbjct: 469 ---PPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGF 525 Query: 454 SRPLAPR---GT---------PTSFSSSSSTDWDLDFGSPVGNQGQHP----GKGSPPGS 497 P A R GT PT +SSS+++ SP G P + P Sbjct: 526 LGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLP 585 Query: 498 SPLQGLENCLKEIPVPV---LRPAWPCS-----SAADRGPRRAEPR-NWTADKE------ 542 P +N VP+ L PA P S S + R P PR ++ E Sbjct: 586 RPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPP 645 Query: 543 -GLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWL 601 G ++A + + G GE P R P++F P Q F++P ++ L Sbjct: 646 PGPLSKAPQP--VPPGVGELPARG-----PRLFDFPPTPLEDQ--FEEPAE-----FKIL 691 Query: 602 PEGSAPKPSPLHCLESALR----------GILPVRPLR--FACVGGPSPSPSPGSSSS-- 647 P+G A + + L+ ++R G+ P PL+ FA + P P+ + ++++ Sbjct: 692 PDGLA---NIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPA 748 Query: 648 ------------FSGSEGEDPRPEPDLWKPLPQERDRLPSC-KPPVPLSPCPGGTPAGSS 694 + ++ E+ +P P L P P + PS +PP P P P + Sbjct: 749 VAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLA 808 Query: 695 GGSPGEDPRRTEPRYC-SGLGAGTAQDPCPVSQLEKRPRVSEASRGLE------LGHGRP 747 G+ +YC G GA + P P+ + P + L G P Sbjct: 809 SVLEGQ-------KYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSP 861 Query: 748 RVAAKTHERLLPQGPP----ELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQEL 803 + +A + + G P E P P P PP L PP + +E+ Sbjct: 862 QPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSL----PPARSESEVLEEI 917 Query: 804 HSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRW 863 L E++ R AT A + RL Q G + + + + Sbjct: 918 SRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQK 977 Query: 864 AHGPGHRH--------LPYWRQKGPTRPKPKILRGQGE------SCRAGDLQGLSR---- 905 H HR + ++G + K K+ + + ++ ++QG + Sbjct: 978 EHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPD 1037 Query: 906 -GTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPL 964 G A +A+P APP+ P PS PP+ + ++P PP Sbjct: 1038 LGGASKAKPPTAPAPPSAP--------------APSAQPTPPSASVPGKKAREEAPGPPG 1083 Query: 965 VPAA 968 V A Sbjct: 1084 VSRA 1087 Score = 59.3 bits (142), Expect = 2e-08 Identities = 238/1009 (23%), Positives = 314/1009 (31%), Gaps = 237/1009 (23%) Query: 102 PEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKP 161 P A AARE L GL SC + PH P + G + PLP P Sbjct: 8 PGARAAREAFALGGL-SCAGAWSSCPPH--PPPRSAWLPGGRCSASIGQPPLPA-----P 59 Query: 162 WPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVP 221 P G+ G PS P ++P P + L+ L C++ +L Sbjct: 60 LPPSH---GSSSGHPSKPYYAPGAPTPR-------------PLHGKLESLHGCVQALL-- 101 Query: 222 GPRHPETSPSFLPPLPSLGTSR-----LTR------------ADLGP--GSPPWAVKTEA 262 R P P L L S TR A+LGP G A Sbjct: 102 --REP-AQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNF 158 Query: 263 VSGDC--------PLQ---GLLHC--------------LKELPEAQDRHPSP----SGVG 293 +G C PL+ LLH +K E P P SG Sbjct: 159 HTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPS 218 Query: 294 NRRLQENPGAWKRGSGG------PGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASC 347 G +RG PG L PPP PP P Sbjct: 219 GEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPP--------------------LPPPPPPP 258 Query: 348 QPGRQPLSPSATGDTRGVPQP---------SWGPEAQAASASSS-------------PLE 385 P PL AT + +P +WGPE + ++ P Sbjct: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAP 318 Query: 386 ALEACLKG---IPPNGSSPSQLPPTS----CSQNPQPGDSRSQKPELQPHRSHSEEATRE 438 A A G +P P PP + C +P S ++ +Q R S Sbjct: 319 AYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS----- 373 Query: 439 PVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDL-----DFGSPVGNQGQ------ 487 V P +CV PSRP GT TS SSSSS++ L + G P + Q Sbjct: 374 -VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEV 432 Query: 488 -HPGKGSPPGSS---PLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEG 543 H G+ P S P G + +P P+ P R R P W Sbjct: 433 SHHGRLGPSAHSSRKPFLGAPAATPHLSLPP-GPSSPPPPPCPRLLRPPPPPAW------ 485 Query: 544 LRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPE 603 L+ AC +AR GE L + + P H+ GF P A+R V Sbjct: 486 LKGPACRAAR---EDGEI-LEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSH 541 Query: 604 GSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLW 663 P+P ++ G P GP P P + DP P P Sbjct: 542 TPPTPPTPTTSSSNSNSGSHSSSP------AGPVSFPPPPYL-----ARSIDPLPRPPSP 590 Query: 664 KPLPQERDRLP--SCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDP 721 PQ+ +P PP P S C T +GS PR + P+ +G G P Sbjct: 591 AQNPQDPPLVPLTLALPPAPPSSCHQNT-SGSFRRPESPRPRVSFPK-TPEVGPGPPPGP 648 Query: 722 CPVSQLEKRPRVSE-ASRGLELGHGRPRVAAKTHE-----RLLPQGPP---ELPSESPPP 772 + P V E +RG L P E ++LP G ++ ES Sbjct: 649 LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRK 708 Query: 773 ELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMR 832 E + V P QP PL++ SL + TA A T Sbjct: 709 EEEQQQHEAGVAP----QP------PLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTT 758 Query: 833 TQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKP------- 885 T + P P LP P A P P + + P P P Sbjct: 759 TTTTATQEEEKKPPP--------ALPPPPPLAKFP-----PPSQPQPPPPPPPSPASLLK 805 Query: 886 ---KILRGQGESCRAGDLQGLSRGTARRARPL--------PPDAPPAEPPGLHCSSSQ-- 932 +L GQ R G + R PL PP A PP S+Q Sbjct: 806 SLASVLEGQKYCYR-----GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGS 860 Query: 933 QLLSSTPSCHAAPPAHPLLAHTGGHQSPLP-PLVPAALPLQGASPPAAS 980 S++ S + P + P+P P+ P P + PPA S Sbjct: 861 PQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARS 909 Score = 42.4 bits (98), Expect = 0.002 Identities = 110/440 (25%), Positives = 139/440 (31%), Gaps = 100/440 (22%) Query: 625 VRPLRFACVGGPSPSP--SPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPL 682 V+P+ A + GPS SPG G E P L PLP P PP P Sbjct: 206 VQPVPPAALSGPSGEEGLSPGGKRR-RGCNSEQTGLPPGL--PLP------PPPLPPPPP 256 Query: 683 SPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLEL 742 P P P SP + T+P S L G A P + P E L Sbjct: 257 PPPPPPPPLPGLATSPPF--QLTKPGLWSTLH-GDAWGP--ERKGSAPPERQEQRHSLPH 311 Query: 743 GHGRPRVAAKTH---ERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPL 799 + P A H RL+P PP P P PP + LPA+ +PP G L Sbjct: 312 PYPYPAPAYTAHPPGHRLVPAAPP-----GPGPR-PPGAESHGCLPAT--RPP---GSDL 360 Query: 800 QQELHSLGAALAEKLDRLATALAGLAQE---------VATMRTQVNRLGRRPQGPGPMGQ 850 ++ + TA A ++ + + G R P P Sbjct: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420 Query: 851 ASWMWTLPRGPRWAHG-------------------PGHRHLPYWRQKGPTRPKPKILRG- 890 + + P HG H LP P P P++LR Sbjct: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 480 Query: 891 ------QGESCRAGD-----LQGLSRGTARRARPLPPDAP-------------------- 919 +G +CRA L+ L GT RP PP P Sbjct: 481 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 540 Query: 920 --PAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLP--------PLVPAAL 969 P PP SSS S S A P + P + PLP P P + Sbjct: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 600 Query: 970 PLQGASPPAASADADVPTSG 989 PL A PPA + TSG Sbjct: 601 PLTLALPPAPPSSCHQNTSG 620 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 69.7 bits (169), Expect = 1e-11 Identities = 198/832 (23%), Positives = 261/832 (31%), Gaps = 154/832 (18%) Query: 90 SRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQ 149 SR S+ G P P P P P+S L +P GP G Sbjct: 909 SRSLSVPGSEDIPPPPTTSPPEPPYST----PPVPSSSGRLTPSPR-----GGPFNPG-S 958 Query: 150 GSPLPIKTA---DKPWP--TR---KEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGI 201 G PLP + D P P TR +E G P H P H Sbjct: 959 GGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHA 1018 Query: 202 SPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTE 261 P + P E+ G L P PSL R PG+P + Sbjct: 1019 HPPHPP---------EMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGS 1069 Query: 262 AVSGDCPLQGLLHCLKELP----EAQDRHPSPSGVGNR----RLQENPGAWKRGSGGPGY 313 A G QG +LP A P+ SG G + + + G ++G G P Sbjct: 1070 AGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLP-- 1127 Query: 314 LLTPPPHPDLGAGG----LLSVKMENSWVQSPP----GPASCQPGRQPLSPSATGDTRGV 365 P P P A ++ E + + P P++ GR S + Sbjct: 1128 ---PAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQ 1184 Query: 366 PQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPEL 425 P+P+ G +S S +P + +PP SPS +P + P D SQ Sbjct: 1185 PEPTGGGGGGGSSPSPAP------AMSPVPP---SPSPVPTPASPSGPATLDFTSQFGAA 1235 Query: 426 QPHRSHSE-----EATREPVLPLGLQSCVRDGPSRPLAPRGTP-TSFSSSSSTDWDL--- 476 + E EA R L L + DG L P S S D + Sbjct: 1236 LVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSA 1295 Query: 477 -------DFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPV------PVLRPAWPCSS 523 GS G G G + G + L P+ L PA P Sbjct: 1296 EPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGL 1355 Query: 524 AADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACH 583 A A R EG A R R EAP + H SP P Sbjct: 1356 AL-----AARERALKESSEGGGAPQ-PPPRPPSPRYEAPPPTPHHHSPHAHHE---PVLR 1406 Query: 584 QRGFKDPGATRPGVWRWLPEGSAPKPSP----------LHCLESALRGILPVRPLRFACV 633 G P R + GS K P LH L G+ P+ + Sbjct: 1407 LWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPL----LLQL 1462 Query: 634 GGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGS 693 G P+P PG S + + E+P + LP L +C+P P++ G P+ Sbjct: 1463 GTEPPAPHPGVSKPWRSAAPEEP-------ERLPLHVRFLENCQPRAPVTS-GRGPPSED 1514 Query: 694 SGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRG--LELGHGRPRVAA 751 G P PRR+ P P P S PR SE + L L P V Sbjct: 1515 GPGVPPPSPRRSVP-------------PSPTS-----PRASEENGLPLLVLPPPAPSVDV 1556 Query: 752 KTHERLL--PQGPP-------ELPSE--SPPPELPPPEAAPPVLPASSLQPPCHCGKPLQ 800 + E L P PP E P +P P P P+ P P + PP P Sbjct: 1557 EDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAP-- 1614 Query: 801 QELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQAS 852 LD A++L EVAT+ + P PGP A+ Sbjct: 1615 -----------PTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAA 1655 Score = 53.9 bits (128), Expect = 8e-07 Identities = 221/926 (23%), Positives = 287/926 (30%), Gaps = 189/926 (20%) Query: 128 PHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRK 187 PH P+ S P G G+ I A+ P +PP SR Sbjct: 864 PHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYL-----------APPAMKFSRSL 912 Query: 188 SHRGQERGTSEAGISPGNSPLQGL-INCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTR 246 S G E SP P + L P PR +P PLP+ + Sbjct: 913 SVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFD- 971 Query: 247 ADLGPGSPPWAV--KTEAVSGDCPLQGLLHCLKELPEAQDRH-PSPSGVGNRRLQENPGA 303 GP P V + +++ PL H P H P P + +P Sbjct: 972 ---GPSPPDTRVGSREKSLYHSGPLPPAHH---HPPHHHHHHAPPPQPHHHHAHPPHPPE 1025 Query: 304 WKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTR 363 + G G P PPP LG L W P P P SPS G Sbjct: 1026 METG-GSPD---DPPPRLALGPQPSL-----RGWRGGGPSPTPGAP-----SPSHHGSAG 1071 Query: 364 GVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLP---PTSCSQNPQPGDSRS 420 G S GP A P A A + +P + P T PQ G Sbjct: 1072 GGGGSSQGP---ALRYFQLPPRAASAAMY-VPARSGRGRKGPLVKQTKVEGEPQKGGG-- 1125 Query: 421 QKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGS 480 L P S + A+ +P + S P + + TS S SS + Sbjct: 1126 ----LPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEP 1181 Query: 481 PVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTAD 540 P Q + G G GSSP P P + P P S + P Sbjct: 1182 PT--QPEPTGGGGGGGSSPS----------PAPAMSPVPPSPSPVPTPASPSGPATLDFT 1229 Query: 541 KEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRW 600 + A + R G + EA RS +S G +D G G Sbjct: 1230 SQFGAALVGAARREGGWQNEARRRSTLFLSTDA------------GDEDGGDGGLGT--- 1274 Query: 601 LPEGSAPKPSPLHCLESALRGILPVRP-LRFACVGGPSPSPSPGSSSSFSGSEGED---- 655 G+AP P H +S G+ P LR G + G+ S G G Sbjct: 1275 ---GAAPGPRLRHS-KSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFT 1330 Query: 656 ----PRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTP-----AGSSGGSPGEDPRRTE 706 PRP L PL + + P PL + GG+P PR Sbjct: 1331 SFLPPRP---LVHPLTGK-----ALDPASPLGLALAARERALKESSEGGGAPQPPPRPPS 1382 Query: 707 PRYCSGLGAGTAQDPC----PVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGP 762 PRY + P PV +L A R ELG+ R + E+ LP P Sbjct: 1383 PRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARR--ELGY---RAGLGSQEKSLPASP 1437 Query: 763 PELPSESPPPELPP--PEAAPPVLPASSLQPPCHCG--KPLQQELHSLGAALAEKLDRLA 818 P S LPP P P +L + P H G KP + +A E+ +RL Sbjct: 1438 PAA-RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWR-------SAAPEEPERLP 1489 Query: 819 TALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQK 878 + L +P+ P G RGP GPG +P + Sbjct: 1490 LHVRFLEN-------------CQPRAPVTSG---------RGPPSEDGPG---VPPPSPR 1524 Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAE------------PPGL 926 P P S RA + GL LPP AP + PP L Sbjct: 1525 RSVPPSPT-------SPRASEENGLP------LLVLPPPAPSVDVEDGEFLFVEPLPPPL 1571 Query: 927 HCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVP 986 S+S + P PL T G PLP A PL PPA +A P Sbjct: 1572 EFSNSFE-----------KPESPL---TPGPPHPLPDTPAPATPLPPVPPPAVAAAP--P 1615 Query: 987 TSGVAPDGIPERPKEPSSLLGGVQRA 1012 T + E ++L G A Sbjct: 1616 TLDSTASSLTSYDSEVATLTQGASAA 1641 Score = 42.7 bits (99), Expect = 0.002 Identities = 200/860 (23%), Positives = 275/860 (31%), Gaps = 202/860 (23%) Query: 151 SPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQG 210 SPL + A + ++ G GG P PP PS R +P +P Sbjct: 1351 SPLGLALAARERALKESSEG--GGAPQPPPRPPSPRYE-------------APPPTPHHH 1395 Query: 211 LINCLKEILVP--GPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCP 268 + E ++ G P+ + L LG+ + P SPP A ++ Sbjct: 1396 SPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSL----PASPPAARRS-------- 1443 Query: 269 LQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGL 328 LLH L P+ GVG LQ L T PP P G Sbjct: 1444 ---LLHRLP---------PTAPGVGPLLLQ---------------LGTEPPAPHPG---- 1472 Query: 329 LSVKMENSWVQSPPGPASCQP-------GRQPLSPSATG------DTRGVPQPSWGPEAQ 375 + W + P P QP +P +G D GVP PS P Sbjct: 1473 ----VSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPS--PRRS 1526 Query: 376 AASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHR-SHSEE 434 + +SP + E NG LPP + S + + G+ +P P S+S E Sbjct: 1527 VPPSPTSPRASEE--------NGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFE 1578 Query: 435 ATREPVLPLGLQSCVRD--GPSRPLAP-------RGTPTSFSSSSS-TDWDLDFGSPVGN 484 P+ P G + D P+ PL P PT S++SS T +D + + Sbjct: 1579 KPESPLTP-GPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQG 1637 Query: 485 QGQHPGKGSPPGS---------------SPLQGLENCLKEIPVPVL--RPAWPCSSAADR 527 PG PPG P G ++ ++E+ P SSA+ Sbjct: 1638 ASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTL 1697 Query: 528 GPRRAEPRNWTADKEGLRAEACESARL---------GQGRGEAPTRSLHLVSPQVFTSSC 578 AE G A L GQ G + T PQ+ T S Sbjct: 1698 SSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPY-PPQLMTPSK 1756 Query: 579 VPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVR----PLRFACVG 634 + R G RPG L + P + + G+L +R P G Sbjct: 1757 LRG---RALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAG 1813 Query: 635 GP-------SPSPSPGSSSS----FSGSEGEDPRPEPDLWKPLPQ-ERDRLPSCKPPVPL 682 GP P P P +SS EG P P P L PL Q + L + K + Sbjct: 1814 GPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGP-PPPPLPGPLAQPQASALATVKASIIS 1872 Query: 683 SPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLEL 742 G S + G P + G G+G D S V E + L+ Sbjct: 1873 ELSSKLQQFGGSSAAGGALP------WARG-GSGGGGD----SHHGGASYVPERTSSLQ- 1920 Query: 743 GHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQE 802 R R++ + LL + L P P LPP V P ++ P Sbjct: 1921 ---RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAP----------- 1966 Query: 803 LHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRP-------QGPGPMGQASWMW 855 A + +T+ L MR + R P P + S + Sbjct: 1967 -----GATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLP 2021 Query: 856 TLPRGPRW----------AHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSR 905 LP GP + G G P+ P P P I G G G L G SR Sbjct: 2022 ILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVP--PHPGISGGLG-----GALSGASR 2074 Query: 906 G-TARRARPLPPDAPPAEPP 924 + R LPPD P P Sbjct: 2075 SLSPTRLLSLPPDKPFGAKP 2094 Score = 41.2 bits (95), Expect = 0.005 Identities = 100/417 (23%), Positives = 131/417 (31%), Gaps = 102/417 (24%) Query: 640 PSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVP-----LSPCPGGTP--AG 692 P+ S S S ED P P P P P PPVP L+P P G P G Sbjct: 904 PAMKFSRSLSVPGSEDIPPPPTTSPPEP------PYSTPPVPSSSGRLTPSPRGGPFNPG 957 Query: 693 SSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAK 752 S G P P + P P P SR L H P Sbjct: 958 SGGPLPASSP-------------ASFDGPSP-------PDTRVGSREKSLYHSGP----- 992 Query: 753 THERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAE 812 LP P+ PP A PP QP H P G + + Sbjct: 993 -----LP------PAHHHPPHHHHHHAPPP-------QPHHHHAHPPHPPEMETGGSPDD 1034 Query: 813 KLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQA---SWMWTLPRGPRWAHGPGH 869 RLA + Q + G R GP P A S + G + GP Sbjct: 1035 PPPRLA------------LGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082 Query: 870 RH-------------LPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRA-RPLP 915 R+ +P +G P K + +GE + G L T+ + +P P Sbjct: 1083 RYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPP 1142 Query: 916 PDAPPAEPPGLHC---------SSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVP 966 A P+E + +SS S S A PP P GG P P Sbjct: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP 1202 Query: 967 AALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGGEHR 1023 A P+ P + + P S P + + ++L+G +R E W E R Sbjct: 1203 AMSPV-----PPSPSPVPTPASPSGPATLDFTSQFGAALVGAARR---EGGWQNEAR 1251 Score = 33.9 bits (76), Expect = 0.81 Identities = 39/133 (29%), Positives = 56/133 (42%), Gaps = 15/133 (11%) Query: 298 QENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPAS---------CQ 348 QE+P R G PG LT PP L A S+ + + V S PG AS Q Sbjct: 411 QESPKYAARRRGPPGTGLTVPP-ALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQ 469 Query: 349 PGRQPLSPS---ATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLP 405 QP +P+ ++G R P G A++ S P +A + +G P + +P + P Sbjct: 470 GQSQPSAPTTKLSSGTLRSASSPR-GARARSPSRGRHPEDA-KRQPRGRPSSSGTPREGP 527 Query: 406 PTSCSQNPQPGDS 418 + PG S Sbjct: 528 AGGTGGSGGPGGS 540 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 68.2 bits (165), Expect = 4e-11 Identities = 213/898 (23%), Positives = 292/898 (32%), Gaps = 168/898 (18%) Query: 176 PSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQ--GLINCLKEILVPGPRHPETSPSFL 233 P PP+ P R T+ PG+ P + + + PG P P Sbjct: 140 PGPPSARPPCRVPP------TTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFP---PRLA 190 Query: 234 PPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVG 293 P+PS G+S G P A+S + P L+ D P+ Sbjct: 191 DPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHA 250 Query: 294 NRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQP 353 + +P + LTPPP P ++ + + PGPAS P Sbjct: 251 SSSPPSDPPLFHCSDA-----LTPPPLPP------------SNNLPAHPGPASQPPVSSA 293 Query: 354 LS--PSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPP----NGSSP-SQLPP 406 P G G P GP A ASS A +A +PP G P +Q P Sbjct: 294 TMHLPLVLGPLGGAPTVE-GPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS 352 Query: 407 TSCSQNPQPGDSRSQKP----ELQPHRSHSEEATREPVLPLGL-QSCVRDGPSRPLAPR- 460 S S + +P R ++P L R P P + Q PS+P+ P Sbjct: 353 ASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSV 412 Query: 461 ----GTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLR 516 G PT S S ++L +G+ P + SP Q P ++ Sbjct: 413 LSLLGLPTPGPSHSDGSFNL-----LGSDAHLPPPPTLSSGSPPQ---------PRHPIQ 458 Query: 517 PAWPCSSAADRGPRRAEPRNWTADKEGL-RAEACESARLGQGRGEAPTRSLHLVSPQVFT 575 P+ P +++ P A K + + +S G G G P L P + Sbjct: 459 PSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPL----PPLAG 514 Query: 576 SSCVP-ACHQRGFKDPGATRPGVWRWLP---EGSAPKPSPLHCLESALRGIL-------P 624 P ++G GA PG+ LP P PSPL L +L G+L P Sbjct: 515 GEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL--LNHSLFGVLTGGGGQPP 572 Query: 625 VRPLRFACVGGPSPSPSPGSSS--SFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPL 682 PL GGP P +PG S + P P L P + L S P + L Sbjct: 573 PEPL-LPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLAL 631 Query: 683 SPCPG-GTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLE 741 P G G + G P +P SGLG P L P + + L Sbjct: 632 GPTAGDGEGSAEGAGGPSGEP-------FSGLGD---LSPLLFPPLSAPPTLIALNSALL 681 Query: 742 LGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLP----ASSL-QPPCHCG 796 P P G P P P+ PP ++ ASSL + P + G Sbjct: 682 AATLDP-----------PSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSG 730 Query: 797 KPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWT 856 +P Q LGA+L L L ++ L + +P GP GQ Sbjct: 731 RPPQLLSPLLGASLLGDLSSLTSSPGALPSLL------------QPPGPLLSGQL----- 773 Query: 857 LPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 G + LP G P P +C LQ +PP Sbjct: 774 -----------GLQLLP-----GGGAPPPLSEASSPLACLLQSLQ------------IPP 805 Query: 917 DAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASP 976 + P E P L S L P A PP L G P+P L L G Sbjct: 806 EQP--EAPCLPPESPASALEPEP---ARPPLSALAPPHGSPDPPVPEL------LTGRGS 854 Query: 977 PAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGG----EHRDPRWGAH 1030 G+ + P R ++P S + AL+ GG R PR H Sbjct: 855 GKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHH 912 Score = 35.8 bits (81), Expect = 0.21 Identities = 66/250 (26%), Positives = 87/250 (34%), Gaps = 45/250 (18%) Query: 767 SESPPPELPPPEAAPPVLPAS-SLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLA 825 S S P E P+ V P S +PPC P L+ +L + ++ A LA Sbjct: 122 SHSSPGEGASPQMFHTVSPGPPSARPPCRV--PPTTPLNGGPGSLPPEPPSVSQAFPTLA 179 Query: 826 QEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKP 885 GPG + +P G R LP P P P Sbjct: 180 ------------------GPGGLFPPRLADPVPSGG----SSSPRFLPRGNAPSPAPPPP 217 Query: 886 KILRGQGESCRAGDLQGLSRGTARRARPLPPDA---PPAEPPGLHCSSSQQLLSSTPSCH 942 + S G S + P P A PP++PP HCS + L+ P Sbjct: 218 PAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDA---LTPPP--- 271 Query: 943 AAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEP 1002 PP++ L AH G + PP+ A + L P A PT V G P P Sbjct: 272 -LPPSNNLPAHPG--PASQPPVSSATMHLPLVLGPLGGA----PT--VEGPGAP--PFLA 320 Query: 1003 SSLLGGVQRA 1012 SSLL +A Sbjct: 321 SSLLSAAAKA 330 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 65.5 bits (158), Expect = 3e-10 Identities = 168/715 (23%), Positives = 231/715 (32%), Gaps = 103/715 (14%) Query: 1 MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLH 60 +R + E V+ G A P + LS G G P G P R S Sbjct: 125 LRISAEETVARGKATEAPKRSALS--------AGARRDTSGPTP---GTPSPAMARRSRA 173 Query: 61 LTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCL 120 V L + P + + P AS + P AA R P GL Sbjct: 174 AGTEVGLPRPAPS---ARPRPPTEGPRKSVSSAS-EHSTTEPSPAARRRPSAGGGL---- 225 Query: 121 PDGPTSQP-HLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP 179 P S+ + TP S SGP+ G +P P + +G AL PP Sbjct: 226 -QRPASRSLSSSATPLSSPARSGPSARGTPRAPA------HPSQPKPKGLQAL----RPP 274 Query: 180 THSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPET--SPSFLPPLP 237 +P R+ + +P PL + P P P + +P L LP Sbjct: 275 QVTPPRKDA-------------APALGPLSS-----SPLATPSPSAPPSPSAPPSLQTLP 316 Query: 238 SLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRL 297 S + ++A GSP T + PL L + P A P L Sbjct: 317 SPPATPPSQATTSLGSPTLQA-THSFLPSPPLSPLATPPPQAPPALALPP---------L 366 Query: 298 QENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPAS----CQPGRQP 353 Q P P L TP P A L+V + + PP P P P Sbjct: 367 QAPPSPPASPPLSP--LATPSPQ----APNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420 Query: 354 LSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNP 413 +SPSAT ++ P + P S +SP + A PP P PP ++ P Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP---PPQAPPPLAAPPLQLAKPP 477 Query: 414 QPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSS--SS 471 P LQ A P Q+ S P++P TP + ++ Sbjct: 478 PQAPPALATPPLQ--------ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 Query: 472 TDWDLDFGSPVGNQGQHPGKGSPPG-SSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPR 530 + P Q P + PG + + G L P P P+ SS Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 589 Query: 531 RAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDP 590 + T+ E LR +S G P P ++C PA RG P Sbjct: 590 AGHSSSATSTPEELRGY--DSGPEGGAAASPP--------PDAELAACHPAAWSRGPAPP 639 Query: 591 GATR--PGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSF 648 A R PG P + P + C G P A GPSP S G +++ Sbjct: 640 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAG 699 Query: 649 SGSEGEDPRPEPDLWKPLP----QERDRLPSCKPPVPLSPCPGGTPAGSSGGSPG 699 +G+ P+ LP Q + L+ G AG SGG PG Sbjct: 700 AGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA--AGGSGGGPG 752 Score = 59.7 bits (143), Expect = 1e-08 Identities = 181/703 (25%), Positives = 229/703 (32%), Gaps = 152/703 (21%) Query: 344 PASCQPGRQPLSPSATGDTRGVPQPSWGPEA-----QAASASSSPLEALEACLKGIPPNG 398 PA+ PG L+P G R P P P A A + PL + G Sbjct: 17 PAARAPGL--LTPRPPGSPR--PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 399 SSP-------SQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRD 451 S+P S+ P + + P + S P P R+ T P PLG Q +R Sbjct: 73 SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRA---SGTTRPG-PLG-QKGLRI 127 Query: 452 GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGS--SPLQGLENCLKE 509 +A RG T S+ L G+ G PG SP + S G E L Sbjct: 128 SAEETVA-RGKATEAPKRSA----LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182 Query: 510 IPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESAR----LGQGRGEAPTRS 565 P P RP P GPR++ ++ E E +AR G G +RS Sbjct: 183 -PAPSARPRPPTE-----GPRKSV----SSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232 Query: 566 LHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPV 625 L +SS P G + G R S PKP L L + P Sbjct: 233 L--------SSSATPLSSPAR---SGPSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPP 279 Query: 626 R--------PLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEP------DLWKP-LPQER 670 R PL + + PSPS P S+ S P P L P L Sbjct: 280 RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339 Query: 671 DRLPS-----------------CKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGL 713 LPS PP+ P P +P S +P P+ L Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS--PQAPNALAVHLL 397 Query: 714 GAGTAQDPCPVSQLEKRPRVSE--ASRGLELGHGRPRVAAKTHE--RLLPQGPPELPSES 769 A + P P Q P S + P +AA + P PP PS + Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457 Query: 770 PPPELPPPEAAPPVLPAS--SLQPPCHCGKPLQ-----------QELHSLGAALAEKLDR 816 PPP+ PPP AAPP+ A PP PLQ Q S A+L + Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSP 515 Query: 817 LATALAGLAQEVATMRTQVN---------RLGRRPQGPGPMGQASWMWTLPRGPR--WAH 865 LAT +A QV + RRP PGP S GPR A Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-------GPRLTLAL 568 Query: 866 GPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPL------PPDAP 919 PG P P R + DL G S L P Sbjct: 569 APG--------------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 614 Query: 920 PAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLP 962 A PP +L + P+ + PA P LA G +PLP Sbjct: 615 AASPP-----PDAELAACHPAAWSRGPAPP-LAFRGAPGAPLP 651 Score = 52.4 bits (124), Expect = 2e-06 Identities = 137/554 (24%), Positives = 182/554 (32%), Gaps = 100/554 (18%) Query: 99 RASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTA 158 R +P A A +GL + P P + D++ + GP S P+ T Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRP------PQVTPPRKDAAPALGPL------SSSPLATP 298 Query: 159 DKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQE--RGTSEAGISPGNSPLQGLINCLK 216 P P +L PSPP PS+ + G + T SP SPL Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358 Query: 217 EILVPGPRHPETSPSFLPPLPSLGTS----------RLTRADLGPGSPPWAVKTEAVSGD 266 L P SP PPL L T L +A P P + Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418 Query: 267 CPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPH--PDLG 324 P+ P A +P + LQ P P TPPP P L Sbjct: 419 PPVS---------PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS--ATPPPQAPPPLA 467 Query: 325 AGGLLSVK--------MENSWVQSPPGPASCQPGRQPLSPSATGDTRGVP-QPSWGPEAQ 375 A L K + +Q+ P P + PG+ P SPSA+ +P P P Q Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-----LPMSPLATPPPQ 522 Query: 376 AASASSSPLEALEACLKGIPPNGSSPS----QLPPT--------------SCSQNPQPGD 417 A ++PL L+ P +SP+ + PPT + + P P Sbjct: 523 APPVLAAPL------LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576 Query: 418 SRSQKPELQ--PHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTP-TSFSSSSSTDW 474 SRS L HS AT P G S GP A P ++ W Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDAELAACHPAAW 632 Query: 475 DLDFGSPVGNQGQHPGKGS--PPGSSPLQGLENC-LKEIPVPVLRPAWPCSSAADRGPRR 531 P+ +G PG PP + P C + E P A P A D GP Sbjct: 633 SRGPAPPLAFRGA-PGAPLPWPPATGPGSADGLCTIYETEGP--ESATPAPGALDPGPSP 689 Query: 532 AEPRNWTADKEGLRA--EACESARLGQGRGEAPTRSL------HLVSPQVFTSSCVPACH 583 A G A + + ARL GE P +L HL+S + ++ A Sbjct: 690 GTSGGKAAAGAGAGASSRSPKQARL----GELPLGALQASVVQHLLSRTLLLAAAEGAAG 745 Query: 584 QRGFKDPGATRPGV 597 G GA GV Sbjct: 746 GSGGGPGGAEGGGV 759 Score = 50.8 bits (120), Expect = 6e-06 Identities = 161/662 (24%), Positives = 213/662 (32%), Gaps = 108/662 (16%) Query: 373 EAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHS 432 +A+A +A+ +P L PP SP PP + + G + + + R+ Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPG--SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 433 EEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKG 492 P +S R GP+R P P S + PV + G+ G Sbjct: 65 IGGATIP------ESAPRAGPTRTSRP---PASGRGERAPPAKNTSPGPVSSPGRASGT- 114 Query: 493 SPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRR--AEPRNWTADKEGLRAEACE 550 + PG +GL +E P SA G RR + P T R Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174 Query: 551 SARLGQGRG----------EAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRW 600 +G R E P +S+ S T PA +R G RP R Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS-PAARRRPSAGGGLQRPAS-RS 232 Query: 601 LPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEP 660 L + P SP SA G +P+ S G + P Sbjct: 233 LSSSATPLSSPARSGPSAR---------------GTPRAPAHPSQPKPKGLQALRPP--- 274 Query: 661 DLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQD 720 + P +D P+ P LS P TP SP P + P L + A Sbjct: 275 ---QVTPPRKDAAPALGP---LSSSPLATP------SPSAPPSPSAPPSLQTLPSPPATP 322 Query: 721 PCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAA 780 P S+A+ L G P + A TH L PP P +PPP+ PP A Sbjct: 323 P------------SQATTSL----GSPTLQA-THSFL--PSPPLSPLATPPPQAPPALAL 363 Query: 781 PPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGR 840 PP+ PP P L L + + LA L A + + Sbjct: 364 PPLQA-----PP---SPPASPPLSPLATPSPQAPNALAVHLLQ-----APFSPPPSPPVQ 410 Query: 841 RPQGPGPMGQASWMWTLP-RGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGD 899 P P S T P + P P + P P P A Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470 Query: 900 LQ-GLSRGTARRARPLPP----DAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHT 954 LQ A A PP +PPA PG S L +P P A P+LA Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA-- 528 Query: 955 GGHQSPL---PPLVPAALPLQG-ASPPAASADADVP----TSGVAPDGIPERPKEPSSLL 1006 +PL PP PA+ LQ PP D V T +AP P + PSS L Sbjct: 529 ----APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584 Query: 1007 GG 1008 G Sbjct: 585 SG 586 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 64.7 bits (156), Expect = 4e-10 Identities = 163/668 (24%), Positives = 211/668 (31%), Gaps = 71/668 (10%) Query: 123 GPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPW-PTRKEGPGALGGEPSPPTH 181 GP P AT + P DG GSP P P K PG G P Sbjct: 1284 GPQGPPGSATAKGERGF---PGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGER 1340 Query: 182 SPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGT 241 P K G G G PG L G PGPR P P P GT Sbjct: 1341 GPRGPKGEPGAP-GQVIGGEGPG---LPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396 Query: 242 S-RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSG-VGNRRLQE 299 + + + D G PP + G+ L GL P P G VG + Sbjct: 1397 AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGL-----------PGSPGPQGPVGPPGKKG 1445 Query: 300 NPGAWKRGSGG-PGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 G + G+ G PG +P G G + K + + PGP + P Sbjct: 1446 EKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF----PGPLGEAGEKGERGPPG 1501 Query: 359 TGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDS 418 +RG+P + P A+ P KG P P+ + P + GD Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGE--KGEPGRPGDPAVVGPAVAGPKGEKGD- 1558 Query: 419 RSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDF 478 + P + P GL GP RG P + + D Sbjct: 1559 ------VGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG-PIGLTGRAGPPGD--- 1608 Query: 479 GSPVGNQGQHPGKGSPPGSSPLQGLENCLKEI--PVPVLRPAWPCSSAADRGPRRAEPRN 536 P G +G PG+ PPG +G + + E P P P A +RG R A Sbjct: 1609 SGPPGEKGD-PGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP-GKAGERGLRGAPGVR 1666 Query: 537 WTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCV---PACHQRGFKDPGAT 593 ++G + + E R G P P V P ++G +PG Sbjct: 1667 GPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKG--EPGDR 1724 Query: 594 RPGVWRWLPEGSAPKP-SPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSE 652 R P+G P +P RG P P V GP+ G Sbjct: 1725 GQEGPRG-PKGDPGLPGAPGERGIEGFRG--PPGPQGDPGVRGPAGEKGDRGPPGLDGRS 1781 Query: 653 GEDPRP--------EPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRR 704 G D +P K RD LP + L P P G P G PGED + Sbjct: 1782 GLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGL-PGPSGPPG--LPGKPGEDGK- 1837 Query: 705 TEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPE 764 GL + P K + + G E G P+ L PQGPP Sbjct: 1838 ------PGLNGKNGEPGDPGEDGRKGEKGDSGASGRE-GRDGPKGERGAPGILGPQGPPG 1890 Query: 765 LPSESPPP 772 LP PP Sbjct: 1891 LPGPVGPP 1898 Score = 55.5 bits (132), Expect = 3e-07 Identities = 265/1101 (24%), Positives = 346/1101 (31%), Gaps = 196/1101 (17%) Query: 25 PSEPGRAVGG------GSHADEGQEPAGCGDPQG--GQPRHSLHLTALVQLVKEIPEFLF 76 P PG+ +GG G D G P+G P+G G P Sbjct: 1349 PGAPGQVIGGEGPGLPGRKGDPG--PSGPPGPRGPLGDPGP------------------- 1387 Query: 77 GEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTD 136 +G P + +G D P P L LP P Q P Sbjct: 1388 ---RGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQG-----PVG 1439 Query: 137 SSCSSGPTGDGVQGSP-LPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERG 195 G GD G+P LP + + PGA+G + P +G ERG Sbjct: 1440 PPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKG-ERG 1498 Query: 196 TSEAGISPGNSPLQGLINCLKEILVPGP--RHPETSPSFLP--PL---PSLGTSRLTRAD 248 S G + G PGP R E P P P++ + + D Sbjct: 1499 PPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGD 1558 Query: 249 LGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGS 308 +GP P A V G+ GL+ P+ P G+ R Sbjct: 1559 VGPAGPRGAT---GVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEK 1615 Query: 309 GGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDT--RGVP 366 G PG P P G G + K + + PPG P P G+ RG P Sbjct: 1616 GDPGRPGPPGPVGPRGRDGEVGEKGD----EGPPG--------DPGLPGKAGERGLRGAP 1663 Query: 367 QPSWGPEAQAASA--------SSSPLEALEACLKGIPPNGSSPSQLPPTS--CSQNPQPG 416 GP + + SP + +G P P +L T + +PG Sbjct: 1664 GVR-GPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722 Query: 417 DSRSQKPELQPHRS---------HSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFS 467 D R Q+ P E R P P G VR GP+ RG P Sbjct: 1723 D-RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG-DPGVR-GPAGEKGDRGPP-GLD 1778 Query: 468 SSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADR 527 S D P G G GK PG L GL + +P P P P D Sbjct: 1779 GRSGLDGKPGAAGPSGPNGA-AGKAGDPGRDGLPGLRG-EQGLPGPSGPPGLPGKPGEDG 1836 Query: 528 GP----RRAEPRNWTAD-KEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPAC 582 P + EP + D ++G + ++ S R G+ + + ++ PQ P Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPV- 1895 Query: 583 HQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSP 642 PG PGV P G+ PK +G+ R LR G P P+ Sbjct: 1896 -----GPPGQGFPGV----PGGTGPKGDRGETGSKGEQGLPGERGLR----GEPGSVPNV 1942 Query: 643 GSSSSFSGSEGEDPRPEPDLWK-------PLPQERDRLPSCK-----PPVPLSPC--PGG 688 +G + R + W P+P ER R P PP P PG Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPVP-ERRRGPKGDSGEQGPPGKEGPIGFPGE 2001 Query: 689 TPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPR-------------VSE 735 G PG P+ GL G P P S L P V E Sbjct: 2002 RGLKGDRGDPG-------PQGPPGLALGERGPPGP-SGLAGEPGKPGIPGLPGRAGGVGE 2053 Query: 736 ASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPP-------------EAAPP 782 A R E G + R GPP LP PP P P E PP Sbjct: 2054 AGRPGERGERGEKGERGEQGR---DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPP 2110 Query: 783 VLPASSLQPPCH--CGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGR 840 L + +P + G + + + E R GL E R G Sbjct: 2111 GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGE----RGMAGPEG- 2165 Query: 841 RPQGPGPMGQASWMWTLPRGPRWAHG-PGHRHLPYWRQKGPTRPK-PKILRGQ-GESCRA 897 +P GP G P GP HG PG P GP P+ P L+G+ GE+ Sbjct: 2166 KPGLQGPRG--------PPGPVGGHGDPGPPGAP--GLAGPAGPQGPSGLKGEPGETGPP 2215 Query: 898 GDLQGLSRGTARRARPLPPD----APPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAH 953 G +GL+ T P PP P PGL + P A Sbjct: 2216 G--RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGS 2273 Query: 954 TGGHQSP-LP-PLVPAALPLQGASP-------PAASADADVPTSGVAPDGIPERPKEPSS 1004 G SP LP P+ P P +P P A + P G+A D + E + Sbjct: 2274 PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAP-GGLAGDLVGEPGAKGDR 2332 Query: 1005 LLGGVQRALQEELWGGEHRDP 1025 L G + E GE DP Sbjct: 2333 GLPGPRGEKGEAGRAGEPGDP 2353 Score = 43.1 bits (100), Expect = 0.001 Identities = 99/432 (22%), Positives = 134/432 (31%), Gaps = 109/432 (25%) Query: 142 GPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGI 201 G G GV GSP P P P +G L G P P GQ E G Sbjct: 2369 GDPGVGVPGSPGP------PGPPGVKGDLGLPGLPGAPGVV-----GFPGQTGPRGEMG- 2416 Query: 202 SPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTE 261 PG S +GL +PGP P P + P P + + D G G P Sbjct: 2417 QPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGP-PGASGLKGDKGDPGVGLPG------ 2469 Query: 262 AVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRG-SGGPGYLLTPPPH 320 P + P G R QE P RG +G PG Sbjct: 2470 ------------------PRGERGEPGIRGEDGRPGQEGP----RGLTGPPGSRGERGEK 2507 Query: 321 PDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGP-----EAQ 375 D+G+ GL K +++ + PPGP + P +G + P + + Sbjct: 2508 GDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGE 2567 Query: 376 AASASSSPLEALEACL--------KGIPPNGSSPSQ---------------LPPT----- 407 S+ L L L GIP + SP + + P Sbjct: 2568 PGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGE 2627 Query: 408 -----SCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGT 462 +C + + GD P +P + + EP +P + ++G P RG Sbjct: 2628 RGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRG- 2686 Query: 463 PTSFSSSSSTDWDLDFGSPVGNQGQH-----PGKGSPPGSSPLQGLENCLKEIPVPVLRP 517 F P G+QG+ PG G PG S G P Sbjct: 2687 ---FDGQP---------GPKGDQGEKGERGTPGIGGFPGPSGNDGSAG-----------P 2723 Query: 518 AWPCSSAADRGP 529 P S RGP Sbjct: 2724 PGPPGSVGPRGP 2735 Score = 38.1 bits (87), Expect = 0.043 Identities = 109/446 (24%), Positives = 131/446 (29%), Gaps = 92/446 (20%) Query: 80 KGAMDSP----ESESRGASLDGERASPEAAAAREPCPLRGLLSCLPD----GPTSQPHLA 131 K ++D P E L G + P + + P RG+ D GP Q Sbjct: 2093 KVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNP 2152 Query: 132 TTPTDSSCSSGPTG----DGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRK 187 P + + GP G G +G P P+ P P PGA G PS K Sbjct: 2153 GLPGERGMA-GPEGKPGLQGPRGPPGPVGGHGDPGP-----PGAPGLAGPAGPQGPSGLK 2206 Query: 188 SHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPE--TSPSFLPPLPSL------ 239 G+ P +GL + +PGP P P P LP Sbjct: 2207 GEPGET-----------GPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGK 2255 Query: 240 ----GTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNR 295 G + D GSP V G L G P P P+G + Sbjct: 2256 PGAPGRDGASGKDGDRGSP-------GVPGSPGLPG--------PVGPKGEPGPTGAPGQ 2300 Query: 296 RLQENPGAWKRGSGGPGYLL-----TPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPG 350 + PGA K G PG L P D G G K E P P Sbjct: 2301 AVVGLPGA-KGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQK 2359 Query: 351 RQPLSPSATGDTR-GVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC 409 P GD GVP S GP L L G P P Q P Sbjct: 2360 GAPGPKGFKGDPGVGVPG-SPGPPGPPGVKGDLGLPGLP----GAPGVVGFPGQTGPRGE 2414 Query: 410 SQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSS 469 P P R P G R+G PL P G P S Sbjct: 2415 MGQPGPSGERGLAG------------------PPG-----REGIPGPLGPPGPPGSVGPP 2451 Query: 470 SSTDWDLDFGSP-VGNQGQHPGKGSP 494 ++ D G P VG G +G P Sbjct: 2452 GASGLKGDKGDPGVGLPGPRGERGEP 2477 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 64.7 bits (156), Expect = 4e-10 Identities = 166/746 (22%), Positives = 236/746 (31%), Gaps = 143/746 (19%) Query: 121 PDGPTSQPHLATTPTDSSCSSGPTGDGVQ--GSPLPIKTADKPWPTRKEGPGALGGEP-S 177 P+G P P GP D +Q G+P I ++ +P + + PG G+P Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI-SSQQPEKIKSQPPGT--GKPIQ 259 Query: 178 PPTHSPSRRKSHRGQERG-----TSEAGISPGNSPLQGLINCLK---------------- 216 PT +P + +R T +A I G S L + K Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP 319 Query: 217 --EILVPGPRHPETSPSFL------------PPLPSLGTSRLTRADLGPGSPPWAVKTEA 262 E PGP P PS L PP+ GT++ LGP PP Sbjct: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP------- 372 Query: 263 VSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTP----- 317 + PS G + L + PG K + PG P Sbjct: 373 ----------------AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416 Query: 318 PPHPDLGAGGLLSVKMENSWVQSP---PGPASC---QPGRQPLSPSATGDTR---GVPQP 368 P P GL S ++P PGP Q G S TG T+ +P P Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Query: 369 SWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNP-QPGDSRSQKPELQP 427 + P Q A P + A P + P P +P QPG ++ P QP Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK--PPSQQP 534 Query: 428 HRSHSEEATREPVLPLGLQS---CVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGN 484 + P P QS + G +PL P PT S+ Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP---PTVSPSAK-------------- 577 Query: 485 QGQHPGKGSPPGSSPLQGLENCLKEIPVPV-LRPAWPCSSAA------DRGPRRAEPRNW 537 Q P +G P PL L +P C + + P E + W Sbjct: 578 --QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635 Query: 538 TADKEGLRAEACESAR-LGQGRGEAPTR-SLHLVSPQVFTSSCV----PACHQRGFKDPG 591 C+ R LG P+ L + V T+S V P Q K Sbjct: 636 LCLN-------CQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA 688 Query: 592 ATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVR---PLRFACVGGPSPSPSPGSSSSF 648 A + L + PK P + L G + P + P+P P S Sbjct: 689 APKQD----LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744 Query: 649 SGSEGEDPRP-EPDLWKPLPQ-ERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTE 706 + D +P +P + KP + KP +P S S P +T+ Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS------KVQSQAEEKTTPPLKTD 798 Query: 707 PRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELP 766 S T + VS + + AS + H P +K +++ P E P Sbjct: 799 SAKPSQSFPPTGE---KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855 Query: 767 SESPPPELPPPEAAPPVLPASSLQPP 792 ++ P P+A P +P S PP Sbjct: 856 KKAQTKMSPKPDAKP--MPKGSPTPP 879 Score = 53.9 bits (128), Expect = 8e-07 Identities = 185/790 (23%), Positives = 260/790 (32%), Gaps = 135/790 (17%) Query: 91 RGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQG 150 RG S+ SP ++P P + P SQP A P S + P Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQ---- 344 Query: 151 SPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPG--NSPL 208 P +K +P T K LG P + S + S ++ G PG +P Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS--SEQPGPKALAQPPGVGKTPA 402 Query: 209 QGLINCLKEILVPGPRHPETS-----------PSFLPPLPSLGTSRLTRADLGPGSPPWA 257 Q PGP P T P P + G ++ GPG P Sbjct: 403 QQ----------PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP-- 450 Query: 258 VKTEAVSGDCPLQ--GLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLL 315 +A G Q G +LP P G Q+ PG+ K S PG Sbjct: 451 -AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ-PGSAKPPSQQPGSTK 508 Query: 316 TPPPHPDLGAGGLLSVKMENSWVQSPPG--PASCQPGRQ---PLSPSATGDTRGVPQPSW 370 PP P G + PP P S +P Q P PSA T+ V Q Sbjct: 509 PPPQQP-----GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563 Query: 371 GPEAQAASASSS--------------PLEALEACLKGIPP--NGSSPSQLPPTSCSQ--- 411 G Q + S S PL L +P N ++ ++ T CS Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF 623 Query: 412 NPQPGDSRSQK---PELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSS 468 NP P + ++ Q R+ + P P P AP T ++ S Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ---------PKLKTAPVTTTSAVSK 674 Query: 469 SSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAW---PCSSA- 524 SS Q P K + P + E K+ P V +P P + A Sbjct: 675 SSPQP-----------QQTSPKKDAAPKQDLSKAPEP--KKPPPLVKQPTLHGSPSAKAK 721 Query: 525 ----ADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVP 580 AD + A P+ + E +A + + Q + PT L + S T +P Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADD-KPKQPKMVKPTTDL-VSSSSATTKPDIP 779 Query: 581 ACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSP 640 + + + T P L SA KPS +S V P + P+ Sbjct: 780 SSKVQSQAEEKTTPP-----LKTDSA-KPS-----QSFPPTGEKVSPFDSKAIPRPASDS 828 Query: 641 S----PGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGG--TPAGSS 694 PG SS G + DP + + K + P KP SP P G AG + Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888 Query: 695 GGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTH 754 +P + P+ E L G+ D P SQ E G G G + ++ Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITD-APKSQ---PTTPQETVTGKLFGFG-ASIFSQAS 943 Query: 755 ERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGK---------PLQQELHS 805 + G P P P P +A P P +S PP G+ P+++E Sbjct: 944 NLISTAGQPG-PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK- 1001 Query: 806 LGAALAEKLD 815 A AEKL+ Sbjct: 1002 --APAAEKLE 1009 Score = 50.1 bits (118), Expect = 1e-05 Identities = 89/383 (23%), Positives = 128/383 (33%), Gaps = 49/383 (12%) Query: 654 EDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPG-------GTPAGSSGGSPGEDPRRTE 706 E +PE + PL Q+ + P+P PG GTP S P + +++ Sbjct: 199 EQGKPEGIIKPPLQQQPPK------PIPKQQGPGRDPLQQDGTPKSISSQQP--EKIKSQ 250 Query: 707 PRYCSGLGAGTAQDP------CPVSQLEKRPRVSEAS--RGLELGHGRPRVAAKTHERLL 758 P G Q P P+ + RP+ +A RG + P + ++ Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310 Query: 759 PQGPP--------ELPSESPPPELP----------PPEAAPPVLPASSLQPPCHCGKPLQ 800 P PP P + PP P P PPV P + +PP P + Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370 Query: 801 QELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRG 860 G+ EK LAQ +T + G +G + P Sbjct: 371 PPAQQTGS---EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL 427 Query: 861 PRWAHGPGHRHLPYWRQKGPTR-PKPKILRGQGESCRAGDLQGLSR--GTARRARPLP-P 916 A PG P +Q GP + P + G+ + + G + S+ G A+ P P Sbjct: 428 QSPAKAPGPTKTPV-QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486 Query: 917 DAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASP 976 PP + PG SQQ S+ P PA P G + P A Q SP Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546 Query: 977 PAASADADVPTSGVAPDGIPERP 999 SA G P +P Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQP 569 Score = 38.9 bits (89), Expect = 0.025 Identities = 61/231 (26%), Positives = 85/231 (36%), Gaps = 46/231 (19%) Query: 760 QGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLAT 819 Q PP P PPP PPP PP+ P +S +P P ++ + A L T Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI---LPKKKLTVASPVTTATPLFDAVT 2460 Query: 820 ALAGLAQEVATMRTQ---VNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWR 876 L + A +R+ V R+ P P +S +P G + H P Sbjct: 2461 TL----ETTAVLRSNGLPVTRICTTAPPPVPPKPSS----IPSGLVFTHRPE-------P 2505 Query: 877 QKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLS 936 K P PKP I + L T + P D P +P GL +SS L Sbjct: 2506 SKPPIAPKPVIPQ-------------LPTTTQK-----PTDIHP-KPTGLSLTSSMTLNL 2546 Query: 937 STPSCHAAP-PAHPLLAHTGG-----HQSPLPPLVPAALPLQGASPPAASA 981 T + + P P PL H+ +S V LP + +P +SA Sbjct: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597 Score = 35.4 bits (80), Expect = 0.28 Identities = 70/305 (22%), Positives = 107/305 (35%), Gaps = 62/305 (20%) Query: 733 VSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPA------ 786 +S++ E + +V K E+ P+G + P + PP+ P + P P Sbjct: 179 ISDSEASQEETTKKQKVVQK--EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236 Query: 787 ---SSLQP------PCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNR 837 SS QP P GKP+Q G + D L A T + + R Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQ------GPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290 Query: 838 -LGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCR 896 +P P P T + P A PGH Q GP +P + Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPP--AQQPGHEK----SQPGPAKPPAQP--------- 335 Query: 897 AGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGG 956 GL++ A++ + P P +PPG ++ P PA P TG Sbjct: 336 ----SGLTKPLAQQPGTVKP---PVQPPG----------TTKPPAQPLGPAKPPAQQTGS 378 Query: 957 HQSPLPPLVPAAL---PLQGASPPAASADADVPTSGV-APDGIPERP--KEPSSLLGGVQ 1010 + P AL P G +P A PT V P + ++P + P+ G + Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438 Query: 1011 RALQE 1015 +Q+ Sbjct: 439 TPVQQ 443 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 64.7 bits (156), Expect = 4e-10 Identities = 166/746 (22%), Positives = 236/746 (31%), Gaps = 143/746 (19%) Query: 121 PDGPTSQPHLATTPTDSSCSSGPTGDGVQ--GSPLPIKTADKPWPTRKEGPGALGGEP-S 177 P+G P P GP D +Q G+P I ++ +P + + PG G+P Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI-SSQQPEKIKSQPPGT--GKPIQ 259 Query: 178 PPTHSPSRRKSHRGQERG-----TSEAGISPGNSPLQGLINCLK---------------- 216 PT +P + +R T +A I G S L + K Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP 319 Query: 217 --EILVPGPRHPETSPSFL------------PPLPSLGTSRLTRADLGPGSPPWAVKTEA 262 E PGP P PS L PP+ GT++ LGP PP Sbjct: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP------- 372 Query: 263 VSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTP----- 317 + PS G + L + PG K + PG P Sbjct: 373 ----------------AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416 Query: 318 PPHPDLGAGGLLSVKMENSWVQSP---PGPASC---QPGRQPLSPSATGDTR---GVPQP 368 P P GL S ++P PGP Q G S TG T+ +P P Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Query: 369 SWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNP-QPGDSRSQKPELQP 427 + P Q A P + A P + P P +P QPG ++ P QP Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK--PPSQQP 534 Query: 428 HRSHSEEATREPVLPLGLQS---CVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGN 484 + P P QS + G +PL P PT S+ Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP---PTVSPSAK-------------- 577 Query: 485 QGQHPGKGSPPGSSPLQGLENCLKEIPVPV-LRPAWPCSSAA------DRGPRRAEPRNW 537 Q P +G P PL L +P C + + P E + W Sbjct: 578 --QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635 Query: 538 TADKEGLRAEACESAR-LGQGRGEAPTR-SLHLVSPQVFTSSCV----PACHQRGFKDPG 591 C+ R LG P+ L + V T+S V P Q K Sbjct: 636 LCLN-------CQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA 688 Query: 592 ATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVR---PLRFACVGGPSPSPSPGSSSSF 648 A + L + PK P + L G + P + P+P P S Sbjct: 689 APKQD----LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744 Query: 649 SGSEGEDPRP-EPDLWKPLPQ-ERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTE 706 + D +P +P + KP + KP +P S S P +T+ Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS------KVQSQAEEKTTPPLKTD 798 Query: 707 PRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELP 766 S T + VS + + AS + H P +K +++ P E P Sbjct: 799 SAKPSQSFPPTGE---KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855 Query: 767 SESPPPELPPPEAAPPVLPASSLQPP 792 ++ P P+A P +P S PP Sbjct: 856 KKAQTKMSPKPDAKP--MPKGSPTPP 879 Score = 53.9 bits (128), Expect = 8e-07 Identities = 185/790 (23%), Positives = 260/790 (32%), Gaps = 135/790 (17%) Query: 91 RGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQG 150 RG S+ SP ++P P + P SQP A P S + P Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQ---- 344 Query: 151 SPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPG--NSPL 208 P +K +P T K LG P + S + S ++ G PG +P Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS--SEQPGPKALAQPPGVGKTPA 402 Query: 209 QGLINCLKEILVPGPRHPETS-----------PSFLPPLPSLGTSRLTRADLGPGSPPWA 257 Q PGP P T P P + G ++ GPG P Sbjct: 403 QQ----------PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP-- 450 Query: 258 VKTEAVSGDCPLQ--GLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLL 315 +A G Q G +LP P G Q+ PG+ K S PG Sbjct: 451 -AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ-PGSAKPPSQQPGSTK 508 Query: 316 TPPPHPDLGAGGLLSVKMENSWVQSPPG--PASCQPGRQ---PLSPSATGDTRGVPQPSW 370 PP P G + PP P S +P Q P PSA T+ V Q Sbjct: 509 PPPQQP-----GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563 Query: 371 GPEAQAASASSS--------------PLEALEACLKGIPP--NGSSPSQLPPTSCSQ--- 411 G Q + S S PL L +P N ++ ++ T CS Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF 623 Query: 412 NPQPGDSRSQK---PELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSS 468 NP P + ++ Q R+ + P P P AP T ++ S Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ---------PKLKTAPVTTTSAVSK 674 Query: 469 SSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAW---PCSSA- 524 SS Q P K + P + E K+ P V +P P + A Sbjct: 675 SSPQP-----------QQTSPKKDAAPKQDLSKAPEP--KKPPPLVKQPTLHGSPSAKAK 721 Query: 525 ----ADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVP 580 AD + A P+ + E +A + + Q + PT L + S T +P Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADD-KPKQPKMVKPTTDL-VSSSSATTKPDIP 779 Query: 581 ACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSP 640 + + + T P L SA KPS +S V P + P+ Sbjct: 780 SSKVQSQAEEKTTPP-----LKTDSA-KPS-----QSFPPTGEKVSPFDSKAIPRPASDS 828 Query: 641 S----PGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGG--TPAGSS 694 PG SS G + DP + + K + P KP SP P G AG + Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888 Query: 695 GGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTH 754 +P + P+ E L G+ D P SQ E G G G + ++ Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITD-APKSQ---PTTPQETVTGKLFGFG-ASIFSQAS 943 Query: 755 ERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGK---------PLQQELHS 805 + G P P P P +A P P +S PP G+ P+++E Sbjct: 944 NLISTAGQPG-PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK- 1001 Query: 806 LGAALAEKLD 815 A AEKL+ Sbjct: 1002 --APAAEKLE 1009 Score = 50.1 bits (118), Expect = 1e-05 Identities = 89/383 (23%), Positives = 128/383 (33%), Gaps = 49/383 (12%) Query: 654 EDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPG-------GTPAGSSGGSPGEDPRRTE 706 E +PE + PL Q+ + P+P PG GTP S P + +++ Sbjct: 199 EQGKPEGIIKPPLQQQPPK------PIPKQQGPGRDPLQQDGTPKSISSQQP--EKIKSQ 250 Query: 707 PRYCSGLGAGTAQDP------CPVSQLEKRPRVSEAS--RGLELGHGRPRVAAKTHERLL 758 P G Q P P+ + RP+ +A RG + P + ++ Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310 Query: 759 PQGPP--------ELPSESPPPELP----------PPEAAPPVLPASSLQPPCHCGKPLQ 800 P PP P + PP P P PPV P + +PP P + Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370 Query: 801 QELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRG 860 G+ EK LAQ +T + G +G + P Sbjct: 371 PPAQQTGS---EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL 427 Query: 861 PRWAHGPGHRHLPYWRQKGPTR-PKPKILRGQGESCRAGDLQGLSR--GTARRARPLP-P 916 A PG P +Q GP + P + G+ + + G + S+ G A+ P P Sbjct: 428 QSPAKAPGPTKTPV-QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486 Query: 917 DAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASP 976 PP + PG SQQ S+ P PA P G + P A Q SP Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546 Query: 977 PAASADADVPTSGVAPDGIPERP 999 SA G P +P Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQP 569 Score = 38.9 bits (89), Expect = 0.025 Identities = 61/231 (26%), Positives = 85/231 (36%), Gaps = 46/231 (19%) Query: 760 QGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLAT 819 Q PP P PPP PPP PP+ P +S +P P ++ + A L T Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI---LPKKKLTVASPVTTATPLFDAVT 2460 Query: 820 ALAGLAQEVATMRTQ---VNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWR 876 L + A +R+ V R+ P P +S +P G + H P Sbjct: 2461 TL----ETTAVLRSNGLPVTRICTTAPPPVPPKPSS----IPSGLVFTHRPE-------P 2505 Query: 877 QKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLS 936 K P PKP I + L T + P D P +P GL +SS L Sbjct: 2506 SKPPIAPKPVIPQ-------------LPTTTQK-----PTDIHP-KPTGLSLTSSMTLNL 2546 Query: 937 STPSCHAAP-PAHPLLAHTGG-----HQSPLPPLVPAALPLQGASPPAASA 981 T + + P P PL H+ +S V LP + +P +SA Sbjct: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597 Score = 35.4 bits (80), Expect = 0.28 Identities = 70/305 (22%), Positives = 107/305 (35%), Gaps = 62/305 (20%) Query: 733 VSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPA------ 786 +S++ E + +V K E+ P+G + P + PP+ P + P P Sbjct: 179 ISDSEASQEETTKKQKVVQK--EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236 Query: 787 ---SSLQP------PCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNR 837 SS QP P GKP+Q G + D L A T + + R Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQ------GPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290 Query: 838 -LGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCR 896 +P P P T + P A PGH Q GP +P + Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPP--AQQPGHEK----SQPGPAKPPAQP--------- 335 Query: 897 AGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGG 956 GL++ A++ + P P +PPG ++ P PA P TG Sbjct: 336 ----SGLTKPLAQQPGTVKP---PVQPPG----------TTKPPAQPLGPAKPPAQQTGS 378 Query: 957 HQSPLPPLVPAAL---PLQGASPPAASADADVPTSGV-APDGIPERP--KEPSSLLGGVQ 1010 + P AL P G +P A PT V P + ++P + P+ G + Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438 Query: 1011 RALQE 1015 +Q+ Sbjct: 439 TPVQQ 443 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 64.3 bits (155), Expect = 6e-10 Identities = 198/773 (25%), Positives = 259/773 (33%), Gaps = 196/773 (25%) Query: 137 SSCSSGPTGDGVQGSPLPIKTADKPWPTRK-------EGPGALGGEPSPPTHSPSRRKSH 189 S SSG G G G P + + WP+ K E P L P PP+ S R Sbjct: 1408 SGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLD- 1466 Query: 190 RGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADL 249 Q ++ AGI L L + + PG HP P L +A Sbjct: 1467 --QVIHSNPAGIQQA---LAQLSSRQGSVTAPGG-HPRHKPG------------LPQAPQ 1508 Query: 250 GPGS-PPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQEN------PG 302 GP PP + + V+ L P ++ P GVG P Sbjct: 1509 GPSPRPPTRYEPQRVNSG---------LSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPK 1559 Query: 303 AWKRGSGGPGYLLT---PPPHPDLGAGGLLSVKMENSWVQSPPG---------------- 343 +R P L PPPH + G L K E Q+ Sbjct: 1560 RRERPPRKPELLQEESLPPPH----SSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLH 1615 Query: 344 ---------PASCQPGRQPLSP-----------SATG-DTRGVPQPSWGPEAQAASASSS 382 P+S +P +PLSP S +G D G Q S GP S SS Sbjct: 1616 TATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGP----CSQRSS 1671 Query: 383 PLEALEACLKGIP--PNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPV 440 P L+ +G P P GSSP P + P PG ++P PH +E RE Sbjct: 1672 PDGGLKGAAEGPPKRPGGSSPLNAVPC---EGP-PGSEPPRRPPPAPHDGDRKELPREQP 1727 Query: 441 LPLGLQSCVRD---------GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGK 491 LP G R GP RP G P F +S D D D VG+ + Sbjct: 1728 LPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTS---DKDSDLRLVVGDSLK---- 1780 Query: 492 GSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACES 551 + + + + IPV P ++A+ AEP++ D E Sbjct: 1781 ------AEKELTASVTEAIPVSRDWELLPSAAAS------AEPQSKNLDSGHCVPE---- 1824 Query: 552 ARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQ--------RGFKDPGATRPGV-----W 598 P+ S + P+VF S P+ Q + + G RPG + Sbjct: 1825 ----------PSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPY 1874 Query: 599 RWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSS-----SSFSGSEG 653 R P P P+P L S L L + L F+ + P SF S Sbjct: 1875 RSQPLYLPPGPAPPSALLSGL--ALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPA 1932 Query: 654 EDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGL 713 P P PD L Q R LPS P P P G SG P SG Sbjct: 1933 FCPSPLPD--TSLLQVRQDLPS---PSDFYSTP-LQPGGQSGFLP------------SGA 1974 Query: 714 GAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPE 773 A P SQL P V+ S P ++ LLP GP PP Sbjct: 1975 PAQQMLLPMVDSQL---PVVNFGSLPPAPPPAPPPLS------LLPVGP-----ALQPPS 2020 Query: 774 L---PPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAG 823 L PPP A VLP+ + P G+ ELH + + +L++ L G Sbjct: 2021 LAVRPPPAPATRVLPSPARPFPASLGR---AELHPVELKPFQDYQKLSSNLGG 2070 Score = 55.1 bits (131), Expect = 3e-07 Identities = 105/426 (24%), Positives = 133/426 (31%), Gaps = 111/426 (26%) Query: 650 GSEGEDPRPEPDLWKPLPQERDRLPSCKP----PVPLSPCPGGTPAGSSGGSPGEDPRRT 705 G +G P EP K E R P +P P P P P PAG + G PG+ P R Sbjct: 375 GKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAG-NWGPPGDYPDR- 432 Query: 706 EPRYCSGLGAGTAQDPCPVSQLEK-RPRVSEASRGLELGHGRPRVAAKTHERLL------ 758 G + P P + E R R ++S + L R R + ER + Sbjct: 433 --------GGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRA 484 Query: 759 -----------------------PQGPPELPSESPPP-----ELPPPEAAPPV-LPASSL 789 P PP PS PP ELP P A PP P Sbjct: 485 ACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPET 544 Query: 790 QPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMG 849 +P P Q + G A A T ++G +T PQ P G Sbjct: 545 EPEEPAQAPPAQSTPTPGVAAA------PTLVSGGGSTSSTSSGSFEASPVEPQLPSKEG 598 Query: 850 QASWMWTLPRGPRWAHGPGHRHLPYWRQK----GPTR---------PK------PKILRG 890 P P P +P K GPTR PK P+ R Sbjct: 599 --------PEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQ 650 Query: 891 QGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPL 950 Q E Q + + PP P PP Q + APP P Sbjct: 651 QQEQLLKQQQQ--HQWQQHQQGSAPPTPVPPSPP-------QPVTLGAVPAPQAPPPPPK 701 Query: 951 LAHTG--GHQSPLPP--------LVPAALP---LQGASPPAASADADVPTSGVAPDGIPE 997 + G G P+PP ++P + LQG P D GV P G+ Sbjct: 702 ALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPP------LDFYPPGVHPSGLVP 755 Query: 998 RPKEPS 1003 R + S Sbjct: 756 RERSDS 761 Score = 52.8 bits (125), Expect = 2e-06 Identities = 215/918 (23%), Positives = 280/918 (30%), Gaps = 188/918 (20%) Query: 187 KSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTR 246 +S G+ER EA GNSP K R PET P PP P R Sbjct: 362 QSASGEER-PPEADGKKGNSP-NSEPPTPKTAWAETSRPPETEPG--PPAPKPPLPPPHR 417 Query: 247 ADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQD------RHPSPSGVG------- 293 G PP GD P +G C PE +D R S S + Sbjct: 418 GPAGNWGPP---------GDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERAR 468 Query: 294 ------NRRLQENPGA--------WKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQ 339 RR+QE A G P L P A Sbjct: 469 RRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAA-------------P 515 Query: 340 SPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGS 399 S P P P P P+ + P+ AQA A S+P + A + GS Sbjct: 516 STPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGS 575 Query: 400 SPS-------------QLPPTSCSQNPQ--PGDSRSQKPELQPHRSHSEEATREPVLPLG 444 + S QLP + P+ P + P+++P + P LG Sbjct: 576 TSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLG 635 Query: 445 LQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLE 504 + P R + W QG P PP SP Q + Sbjct: 636 YPKYQKSLPPR-FQRQQQEQLLKQQQQHQWQQH------QQGSAPPTPVPP--SPPQPV- 685 Query: 505 NCLKEIPVPVLRPAWPCS--SAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAP 562 L +P P P P + A P P N+ D + RL QGR Sbjct: 686 -TLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNF--DPRWMMIPPYVDPRLLQGR---- 738 Query: 563 TRSLHLVSPQVFTSSCVPACHQRGFKDPGAT--------RPGVWR------------WLP 602 L P V S VP R D G + P + R W+ Sbjct: 739 -PPLDFYPPGVHPSGLVP----RERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793 Query: 603 EGSAPKPSPLHCLESALRGILPV--RPLRFACVGGPSPSPSPGSSSSF--SGSEG----- 653 + P+ L S LR + +R P P P S F +G+ G Sbjct: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853 Query: 654 ---EDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYC 710 E+P P P W P D + + P P P A +G G P R Sbjct: 854 FPLEEPGPRPLPW---PPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPAR------ 904 Query: 711 SGLGAGTAQDPCP--VSQLEKR--PRVSEASRGL--ELGHGRPRVAA-------KTHERL 757 G+G+G P P S+ E R PR + RG+ E PR A T Sbjct: 905 -GVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEE 963 Query: 758 LPQGPPELPSESPPPELPPP-EAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDR 816 LP P E E+P P P P + L PP P + E++ Sbjct: 964 LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYS---YERVGP 1020 Query: 817 LATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPR--WAHGPGHRHLPY 874 + G + A R G R +G S+ R GP H P Sbjct: 1021 TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR 1080 Query: 875 WRQKGPTR---------PKPKILRGQ--GESCRAGDLQGLSR-------GTARRA--RPL 914 R TR PK + RG G DL + GT + P Sbjct: 1081 GRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP 1140 Query: 915 PPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGA 974 PP APP+ P + ++ + P P GG + P P + P G Sbjct: 1141 PPGAPPSPAPARFTARGGRVFT--------PRGVPSRRGRGGGRPP-PQVCP------GW 1185 Query: 975 SPPAASADADVPTSGVAP 992 SPPA S P +G P Sbjct: 1186 SPPAKSLAPKKPPTGPLP 1203 Score = 48.1 bits (113), Expect = 4e-05 Identities = 197/861 (22%), Positives = 283/861 (32%), Gaps = 162/861 (18%) Query: 114 RGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPL---PIKTADK---PWPTRKE 167 +G+ S P P P+LA+ P G +G G P+ P++ PWP + Sbjct: 819 KGMRSETPPVPPPPPYLASYP-------GFPENGAPGPPISRFPLEEPGPRPLPWPPGSD 871 Query: 168 GPGALGGEPSPPTHSPSRRKSHR--GQERGTSEA-GISPGNSPLQGLINCLKEILVPGPR 224 + + PP P + ++ + G E G A G+ G QG P PR Sbjct: 872 EVAKI--QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGG---QG---------PPPPR 917 Query: 225 HPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELP---- 280 + + P P G+SR PG+PP +G ++ELP Sbjct: 918 RESRTETRWGPRP--GSSRRGIPPEEPGAPPRR------AGPIKKPPPPTKVEELPPKPL 969 Query: 281 EAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQS 340 E D P P P K G G PP+ +L + ++ + Sbjct: 970 EQGDETPKPP---------KPDPLKITKGKLGGPKETPPNGNLSP----APRLRRDYSYE 1016 Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACL-----KGIP 395 GP SC+ GR A G RG G A S G P Sbjct: 1017 RVGPTSCR-GRGRGEYFARG--RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGP 1073 Query: 396 -----PNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 P G + S+ P R + E S+ A + P + + Sbjct: 1074 NHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLT 1133 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHP-GKGSPPGSSPLQGLENCLKE 509 P P P G P S + + T +P G + G G PP Sbjct: 1134 QVPLAP-PPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPP-------------- 1178 Query: 510 IPVPVLRPAW--PCSSAADRGPRRAE-PRNWTADKEGL---------RAEACESARLGQG 557 P + P W P S A + P P + KE L R + + +G Sbjct: 1179 ---PQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGME 1235 Query: 558 RGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLES 617 GE P R H + Q P + + A R GS KPS L + Sbjct: 1236 DGERPRRRRHGRAQQ---QDKPPRFRRLKQERENAAR---------GSEGKPSLT--LPA 1281 Query: 618 ALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQ------ERD 671 + G P L V P+P + S S + E W+ + ER Sbjct: 1282 SAPG--PEEALTTVTVA-PAPRRAAAKSPDLSNQNSDQANEE---WETASESSDFTSERR 1335 Query: 672 RLPSCKPPVPLSPCPGGTPAGSSGGS-PGEDP--RRTEPRYCSGLGAGTAQDPCPVSQLE 728 PPV L+P GTP G GG+ PG R + L + P + + Sbjct: 1336 GDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQ 1395 Query: 729 KR---PRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLP 785 R P S G G G +T P + SP PPE PP LP Sbjct: 1396 NRRPGPGGKAGSSGSSSGGGGGGPGGRTG----PGRGDKRSWPSPKNRSRPPEERPPGLP 1451 Query: 786 ASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGP 845 P L Q +HS A + + L +L++ + R + L + PQGP Sbjct: 1452 LPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPG-LPQAPQGP 1510 Query: 846 GPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSR 905 P + P+ + G P++ + GP ++RG G + R D G+S Sbjct: 1511 SPRPPTRY------EPQRVNS-GLSSDPHFEEPGP------MVRGVGGTPR--DSAGVS- 1554 Query: 906 GTARRARPLPP---DAPPAEP 923 P PP + PP +P Sbjct: 1555 -------PFPPKRRERPPRKP 1568 Score = 40.0 bits (92), Expect = 0.011 Identities = 114/488 (23%), Positives = 156/488 (31%), Gaps = 136/488 (27%) Query: 52 GGQPRHSLHLTALVQLVKEIPEFLFGEVK---GAMDSPESESRGASLDGERASPEAAAAR 108 GG PRH L Q P + + G P E G + G +P +A Sbjct: 1494 GGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGV 1553 Query: 109 EPCPLRGLLSCLPDGPTSQPHL----ATTPTDSS--CSSGPTGDGVQGSPLPIKTADKPW 162 P P + + P +P L + P SS S P G G Q Sbjct: 1554 SPFPPKRR-----ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAE----------- 1597 Query: 163 PTRKEGPGALGGEPSPPTHSPSRRKSHR------------------GQERGTSEAGIS-P 203 +R G AL H+ + RKS+R G E S++G+ Sbjct: 1598 -SRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLS 1656 Query: 204 GNSPLQGLINCLKEILVPGPRHPETSP-------SFLPPLPSLGTSRLTRADLG--PGS- 253 G+S + GP +SP + PP G+S L PGS Sbjct: 1657 GDSQVSS-----------GPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSE 1705 Query: 254 PPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGY 313 PP GD KELP Q P P +G R Q + G P + Sbjct: 1706 PPRRPPPAPHDGD---------RKELPREQPLPPGP--IGTERSQRTDRGTEPGPIRPSH 1754 Query: 314 LLTPP---------------------PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQ 352 PP +L A ++ + W P AS +P + Sbjct: 1755 RPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSK 1814 Query: 353 PLS-------PSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLP 405 L PS++G R P+ +G +A SSS + G+ SQL Sbjct: 1815 NLDSGHCVPEPSSSGQ-RLYPEVFYG----SAGPSSSQISG-----------GAMDSQLH 1858 Query: 406 PTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTS 465 P S G R P L P+RS P P L S LA +G Sbjct: 1859 PNS-------GGFRPGTPSLHPYRSQPLYLPPGPAPPSALLS--------GLALKGQFLD 1903 Query: 466 FSSSSSTD 473 FS+ +T+ Sbjct: 1904 FSTMQATE 1911 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 63.9 bits (154), Expect = 7e-10 Identities = 138/594 (23%), Positives = 184/594 (30%), Gaps = 103/594 (17%) Query: 280 PEAQ-DRHPSPSGVG---------NRRLQENPGAW----KRGSGGPGYLLTPPPHPDLGA 325 PEA + HPS + G +R Q PGA + GG G +L+ PP G Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238 Query: 326 GGLLSVKMENSWVQSPP----------GPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQ 375 G SV N Q PP G + P + P +P G+ P P+ P Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH-- 296 Query: 376 AASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEA 435 + + P AL P N +S S P P PG S Q Sbjct: 297 -VTPNLPPPPALR------PLNNASAS---PPGLGAQPLPGHLPSPHAMGQGMGGLPPGP 346 Query: 436 TREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS-- 493 + P L S S P P P S SSSSS S + P + Sbjct: 347 EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406 Query: 494 --PPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACES 551 P P L + P +P+ P + +GP P Sbjct: 407 SYPHSFPPPTSLS--VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464 Query: 552 ARLGQGRGEAPTRSLH----LVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAP 607 + Q P + H Q Q+ + G PG + EG + Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS 524 Query: 608 KPSPLHCLESALRGILPVRP-----------LRFACVGGPSPSPSPGSSSSFSGSEG--- 653 + + + +L + P P + ++ G P S S+SS S S+G Sbjct: 525 HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584 Query: 654 -------EDPRPEPDLWKPLP---QERDRLPSCKPPVPLSPC-------PGGTPAGSSGG 696 + P+ P + P+P L + V SP PG P G Sbjct: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644 Query: 697 SPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHER 756 SPG T P Y G P + P S G +P Sbjct: 645 SPGAYKTATPPGYKPG--------SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696 Query: 757 LLPQGPPELPSESPPPELP---PPEAA---------------PPVLPASSLQPP 792 L P GP LPS PPP P PP +A PV PA S PP Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750 Score = 55.1 bits (131), Expect = 3e-07 Identities = 165/657 (25%), Positives = 215/657 (32%), Gaps = 141/657 (21%) Query: 405 PPTSCSQNPQPGDSRSQKPE--LQPHRSHSE---EATREPVLPLGLQSCVRDGPSRP-LA 458 PP +PQP DS ++PE +PH S + A EP Q+ P P L Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220 Query: 459 PRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPA 518 P GT S S VG G + GK PP ++P+ + P P P Sbjct: 221 PGGTGGVLSGPPMGPKGGGAASSVG--GPNGGKQHPPPTTPISVSSSGASGAP-PTKPPT 277 Query: 519 WPCSSAADRGPRRAEPRNWTADKEGLRAEAC-----ESARLGQGRGEAPTRSLHLVSPQV 573 P P P N+ L ++ G G P HL SP Sbjct: 278 TPVGGG--NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-HLPSP-- 332 Query: 574 FTSSCVPACHQRGFKDPGATRPGVWRWLPE-GSAPKPSPLHCLESALRGILPVRPLRFAC 632 H G + G PG PE G PSP H L A P P+RF Sbjct: 333 ---------HAMG-QGMGGLPPG-----PEKGPTLAPSP-HSLPPA-SSSAPAPPMRFP- 374 Query: 633 VGGPSPSPSPGSSSSFSGSEGEDPRPE----PDLWKPLPQERDRLPSCKPPV-------- 680 S S + SSSS S S P P P P S +PP Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434 Query: 681 -------PLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVS-------- 725 P P P G +S PG P T GA + P PVS Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPST--------GAQSTAHP-PVSTHHHHHQQ 485 Query: 726 QLEKRPRVSEASRGLELGHG-----------RPRVAAKTHERLLPQGPPELPSESP---- 770 Q +++ + + + + HG P +H P L S P Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPG 545 Query: 771 PPELPPPEA----------APPVLPASSLQPPCHCGK-PLQQELHSLGAALA----EKLD 815 P LPPP + PPV +S+ G P S G A + Sbjct: 546 PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVP 605 Query: 816 RLATALAGLAQEVATMRTQ-VNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPY 874 + T+ A L+ +AT+ + P GP P G+ + P + A PG++ Sbjct: 606 TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA---PSPGAYKTATPPGYK---- 658 Query: 875 WRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPL--PPDAPPAEPPGLHCSSSQ 932 P P P G R G GT + P P PPA P G Sbjct: 659 -----PGSP-PSFRTGTPPGYR-GTSPPAGPGTFKPGSPTVGPGPLPPAGPSG------- 704 Query: 933 QLLSSTPSCHAAPPAHPLLAHT-------GGHQSPLPPLVPAALPLQGASPPAASAD 982 L S P AAP + P L+ T +++P P+ PA P SPP D Sbjct: 705 --LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSP----SPPPKVVD 755 Score = 50.4 bits (119), Expect = 8e-06 Identities = 98/395 (24%), Positives = 119/395 (30%), Gaps = 104/395 (26%) Query: 637 SPSPSPGSSSSFSGSEGEDPRP--EPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSS 694 SP S S SG RP P L+ P PQ D P +P P P TP G Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR-QPEASFEPHPSVTPTGYH 195 Query: 695 G-----------GSPGEDPRRTE--PRYCSGLGAGTAQDPC----------PVSQLEKRP 731 PG P + P G+ +G P P + P Sbjct: 196 APMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP 255 Query: 732 RVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPP-------PELPPPEAAPPVL 784 + S G P T P G LPS PP P LPPP A P+ Sbjct: 256 PTTPISVSSSGASGAPPTKPPT----TPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311 Query: 785 PASSLQPPCHCGKPLQQEL---HSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRR 841 AS+ PP +PL L H++G +G Sbjct: 312 NASA-SPPGLGAQPLPGHLPSPHAMGQG----------------------------MGGL 342 Query: 842 PQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQ 901 P GP +GP A P LP P P S A Sbjct: 343 PPGP------------EKGPTLA--PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA--S 386 Query: 902 GLSRGTARRARPLP-----PDAPPAEPPGLHCSSSQQ--------LLSSTPSCHAAPPAH 948 S ++ A P P P P + PP S S Q L S PP Sbjct: 387 SSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446 Query: 949 P---LLAHTGGHQSPLPPLVPAALPLQGASPPAAS 980 P LLA++ H P PP A A PP ++ Sbjct: 447 PYGRLLANSNAHPGPFPPSTGAQ---STAHPPVST 478 Score = 43.5 bits (101), Expect = 0.001 Identities = 103/474 (21%), Positives = 141/474 (29%), Gaps = 81/474 (17%) Query: 86 PESESRGASLDGERASPEAAAAREPCP--LRGLLSCLPDGPTSQPHLATTPTDSSCSSGP 143 P + G + G PE P P L S P P P+ +++ + ++ SS Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389 Query: 144 TGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISP 203 + SP P A +P P +L PP ++ S +G P Sbjct: 390 SSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQG-------P 442 Query: 204 GNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAV 263 P G +L HP P PS G PP V T Sbjct: 443 PPPPPYG------RLLANSNAHPGPFP------PSTGAQ-------STAHPP--VSTHHH 481 Query: 264 SGDCPLQGLLHCLKELPEAQDRH----PSPSGV------GNRRLQENPGAWKRGSGG--- 310 Q ++ + Q H P P G G +P A G Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRP 541 Query: 311 --PGYLLTPPPHPDL-----GAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTR 363 PG PPPH + G G NS + G C PS + + Sbjct: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS------HPSPSQGPQ 595 Query: 364 GVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQL-PPTSCSQNPQPGDSRSQK 422 G P P P + SS+ L + A + P + S PP + P PG ++ Sbjct: 596 GAPYPF--PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT 653 Query: 423 PELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSST--DWDLDFGS 480 P +P P ++ G R +P P +F S T L Sbjct: 654 P-----------PGYKPGSPPSFRTGTPPG-YRGTSPPAGPGTFKPGSPTVGPGPLPPAG 701 Query: 481 PVGNQGQHPGKGSPPGSSPLQGL--------ENCLKEIPVPVLRPAWPCSSAAD 526 P G P +P PL E E PVP R P D Sbjct: 702 PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755 Score = 39.7 bits (91), Expect = 0.015 Identities = 168/750 (22%), Positives = 229/750 (30%), Gaps = 157/750 (20%) Query: 127 QPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRR 186 +PH + TPT P + +P P P + PG GG S P P Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAP-----PGAPPPHPQLYPGGTGGVLSGPPMGP--- 235 Query: 187 KSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTR 246 + G + + + N G +HP PP + S Sbjct: 236 ------KGGGAASSVGGPNG---------------GKQHP-------PPTTPISVS---- 263 Query: 247 ADLGPGSPPWAVKTEAVSGDC-----PLQGLLHCLKELPEAQDRHP------SPSGVGNR 295 + G+PP T V G P H LP P SP G+G + Sbjct: 264 SSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQ 323 Query: 296 RLQ---ENPGAWKRGSGG------PGYLLTPPPH---PDLGAGGLLSVKMENSWVQSPPG 343 L +P A +G GG G L P PH P + ++ S S Sbjct: 324 PLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383 Query: 344 PASCQPGRQPLSPSATGDTRGVPQ-PSWGPEAQAASASSSPLEALEACL-------KGIP 395 AS S S ++ +P P P + S S+ P + + L +G P Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443 Query: 396 PNGSSPSQLPPTSCSQNPQPGDSRSQK---PELQPHRSHSEEATREPVLPLGLQSCVRD- 451 P L ++ P P + +Q P + H H ++ ++ Q + Sbjct: 444 PPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH 503 Query: 452 -GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS----PPGSSPLQGLENC 506 G S P P P SS P GS PPG + L Sbjct: 504 HGNSGPPPPGAFPHPLEGGSSHH--------AHPYAMSPSLGSLRPYPPGPAHL------ 549 Query: 507 LKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAP---- 562 P P + ++ S A GP + N ++ + C QG AP Sbjct: 550 ----PPPHSQVSY--SQAGPNGPPVSSSSN-SSSSTSQGSYPCSHPSPSQGPQGAPYPFP 602 Query: 563 -----TRSLHLVSPQVFTSSCVPACHQRGFKDPG-------ATRPGVWRWL-PEGSAP-- 607 T S +S + T + PA ++ PG A PG ++ P G P Sbjct: 603 PVPTVTTSSATLSTVIATVASSPAGYKTA-SPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 608 KPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPE-PDLWKPL 666 PS RG P G P+ P P + SG P P P PL Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721 Query: 667 --------PQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTA 718 P E P + PVP + P P S R G + Sbjct: 722 SATQIKQEPAEEYETP--ESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCAR 779 Query: 719 QD----PCPVSQL--------EKRPRVSEASRGLELGHGRPRVAAKTHER---------- 756 D P S+L EK R +E E R R K ER Sbjct: 780 SDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSV 839 Query: 757 -LLPQG--PPELPSESPPPELPPPEAAPPV 783 L +G P E PS P P PP E V Sbjct: 840 KLAQEGRAPVECPSLGPVPHRPPFEPGSAV 869 Score = 32.3 bits (72), Expect = 2.4 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 15/109 (13%) Query: 902 GLSRGTARRARP--------LPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAP---PAHPL 950 GLS+G AR P PPD+ P +P +S + S TP+ + AP P + Sbjct: 150 GLSQGPARPYHPPPLFPPSPQPPDSTPRQPE----ASFEPHPSVTPTGYHAPMEPPTSRM 205 Query: 951 LAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERP 999 G P P L P + PP +S P+G + P Sbjct: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254 Score = 31.2 bits (69), Expect = 5.3 Identities = 28/88 (31%), Positives = 36/88 (40%), Gaps = 10/88 (11%) Query: 915 PPDAPPAEPPGLHCSSSQQLLSSTP-SCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQG 973 PP APP P L+ + +LS P A + GG Q P PP P ++ G Sbjct: 209 PPGAPPPHPQ-LYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP-PPTTPISVSSSG 266 Query: 974 AS--PPAASADADVPTSGVAPDGIPERP 999 AS PP PT+ V +P P Sbjct: 267 ASGAPPTKP-----PTTPVGGGNLPSAP 289 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 63.9 bits (154), Expect = 7e-10 Identities = 138/594 (23%), Positives = 184/594 (30%), Gaps = 103/594 (17%) Query: 280 PEAQ-DRHPSPSGVG---------NRRLQENPGAW----KRGSGGPGYLLTPPPHPDLGA 325 PEA + HPS + G +R Q PGA + GG G +L+ PP G Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238 Query: 326 GGLLSVKMENSWVQSPP----------GPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQ 375 G SV N Q PP G + P + P +P G+ P P+ P Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH-- 296 Query: 376 AASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEA 435 + + P AL P N +S S P P PG S Q Sbjct: 297 -VTPNLPPPPALR------PLNNASAS---PPGLGAQPLPGHLPSPHAMGQGMGGLPPGP 346 Query: 436 TREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS-- 493 + P L S S P P P S SSSSS S + P + Sbjct: 347 EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406 Query: 494 --PPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACES 551 P P L + P +P+ P + +GP P Sbjct: 407 SYPHSFPPPTSLS--VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464 Query: 552 ARLGQGRGEAPTRSLH----LVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAP 607 + Q P + H Q Q+ + G PG + EG + Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS 524 Query: 608 KPSPLHCLESALRGILPVRP-----------LRFACVGGPSPSPSPGSSSSFSGSEG--- 653 + + + +L + P P + ++ G P S S+SS S S+G Sbjct: 525 HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584 Query: 654 -------EDPRPEPDLWKPLP---QERDRLPSCKPPVPLSPC-------PGGTPAGSSGG 696 + P+ P + P+P L + V SP PG P G Sbjct: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644 Query: 697 SPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHER 756 SPG T P Y G P + P S G +P Sbjct: 645 SPGAYKTATPPGYKPG--------SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696 Query: 757 LLPQGPPELPSESPPPELP---PPEAA---------------PPVLPASSLQPP 792 L P GP LPS PPP P PP +A PV PA S PP Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750 Score = 55.1 bits (131), Expect = 3e-07 Identities = 165/657 (25%), Positives = 215/657 (32%), Gaps = 141/657 (21%) Query: 405 PPTSCSQNPQPGDSRSQKPE--LQPHRSHSE---EATREPVLPLGLQSCVRDGPSRP-LA 458 PP +PQP DS ++PE +PH S + A EP Q+ P P L Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220 Query: 459 PRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPA 518 P GT S S VG G + GK PP ++P+ + P P P Sbjct: 221 PGGTGGVLSGPPMGPKGGGAASSVG--GPNGGKQHPPPTTPISVSSSGASGAP-PTKPPT 277 Query: 519 WPCSSAADRGPRRAEPRNWTADKEGLRAEAC-----ESARLGQGRGEAPTRSLHLVSPQV 573 P P P N+ L ++ G G P HL SP Sbjct: 278 TPVGGG--NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-HLPSP-- 332 Query: 574 FTSSCVPACHQRGFKDPGATRPGVWRWLPE-GSAPKPSPLHCLESALRGILPVRPLRFAC 632 H G + G PG PE G PSP H L A P P+RF Sbjct: 333 ---------HAMG-QGMGGLPPG-----PEKGPTLAPSP-HSLPPA-SSSAPAPPMRFP- 374 Query: 633 VGGPSPSPSPGSSSSFSGSEGEDPRPE----PDLWKPLPQERDRLPSCKPPV-------- 680 S S + SSSS S S P P P P S +PP Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434 Query: 681 -------PLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVS-------- 725 P P P G +S PG P T GA + P PVS Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPST--------GAQSTAHP-PVSTHHHHHQQ 485 Query: 726 QLEKRPRVSEASRGLELGHG-----------RPRVAAKTHERLLPQGPPELPSESP---- 770 Q +++ + + + + HG P +H P L S P Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPG 545 Query: 771 PPELPPPEA----------APPVLPASSLQPPCHCGK-PLQQELHSLGAALA----EKLD 815 P LPPP + PPV +S+ G P S G A + Sbjct: 546 PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVP 605 Query: 816 RLATALAGLAQEVATMRTQ-VNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPY 874 + T+ A L+ +AT+ + P GP P G+ + P + A PG++ Sbjct: 606 TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA---PSPGAYKTATPPGYK---- 658 Query: 875 WRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPL--PPDAPPAEPPGLHCSSSQ 932 P P P G R G GT + P P PPA P G Sbjct: 659 -----PGSP-PSFRTGTPPGYR-GTSPPAGPGTFKPGSPTVGPGPLPPAGPSG------- 704 Query: 933 QLLSSTPSCHAAPPAHPLLAHT-------GGHQSPLPPLVPAALPLQGASPPAASAD 982 L S P AAP + P L+ T +++P P+ PA P SPP D Sbjct: 705 --LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSP----SPPPKVVD 755 Score = 50.4 bits (119), Expect = 8e-06 Identities = 98/395 (24%), Positives = 119/395 (30%), Gaps = 104/395 (26%) Query: 637 SPSPSPGSSSSFSGSEGEDPRP--EPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSS 694 SP S S SG RP P L+ P PQ D P +P P P TP G Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR-QPEASFEPHPSVTPTGYH 195 Query: 695 G-----------GSPGEDPRRTE--PRYCSGLGAGTAQDPC----------PVSQLEKRP 731 PG P + P G+ +G P P + P Sbjct: 196 APMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP 255 Query: 732 RVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPP-------PELPPPEAAPPVL 784 + S G P T P G LPS PP P LPPP A P+ Sbjct: 256 PTTPISVSSSGASGAPPTKPPT----TPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311 Query: 785 PASSLQPPCHCGKPLQQEL---HSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRR 841 AS+ PP +PL L H++G +G Sbjct: 312 NASA-SPPGLGAQPLPGHLPSPHAMGQG----------------------------MGGL 342 Query: 842 PQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQ 901 P GP +GP A P LP P P S A Sbjct: 343 PPGP------------EKGPTLA--PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA--S 386 Query: 902 GLSRGTARRARPLP-----PDAPPAEPPGLHCSSSQQ--------LLSSTPSCHAAPPAH 948 S ++ A P P P P + PP S S Q L S PP Sbjct: 387 SSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446 Query: 949 P---LLAHTGGHQSPLPPLVPAALPLQGASPPAAS 980 P LLA++ H P PP A A PP ++ Sbjct: 447 PYGRLLANSNAHPGPFPPSTGAQ---STAHPPVST 478 Score = 43.5 bits (101), Expect = 0.001 Identities = 103/474 (21%), Positives = 141/474 (29%), Gaps = 81/474 (17%) Query: 86 PESESRGASLDGERASPEAAAAREPCP--LRGLLSCLPDGPTSQPHLATTPTDSSCSSGP 143 P + G + G PE P P L S P P P+ +++ + ++ SS Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389 Query: 144 TGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISP 203 + SP P A +P P +L PP ++ S +G P Sbjct: 390 SSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQG-------P 442 Query: 204 GNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAV 263 P G +L HP P PS G PP V T Sbjct: 443 PPPPPYG------RLLANSNAHPGPFP------PSTGAQ-------STAHPP--VSTHHH 481 Query: 264 SGDCPLQGLLHCLKELPEAQDRH----PSPSGV------GNRRLQENPGAWKRGSGG--- 310 Q ++ + Q H P P G G +P A G Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRP 541 Query: 311 --PGYLLTPPPHPDL-----GAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTR 363 PG PPPH + G G NS + G C PS + + Sbjct: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS------HPSPSQGPQ 595 Query: 364 GVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQL-PPTSCSQNPQPGDSRSQK 422 G P P P + SS+ L + A + P + S PP + P PG ++ Sbjct: 596 GAPYPF--PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT 653 Query: 423 PELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSST--DWDLDFGS 480 P +P P ++ G R +P P +F S T L Sbjct: 654 P-----------PGYKPGSPPSFRTGTPPG-YRGTSPPAGPGTFKPGSPTVGPGPLPPAG 701 Query: 481 PVGNQGQHPGKGSPPGSSPLQGL--------ENCLKEIPVPVLRPAWPCSSAAD 526 P G P +P PL E E PVP R P D Sbjct: 702 PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755 Score = 39.7 bits (91), Expect = 0.015 Identities = 168/750 (22%), Positives = 229/750 (30%), Gaps = 157/750 (20%) Query: 127 QPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRR 186 +PH + TPT P + +P P P + PG GG S P P Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAP-----PGAPPPHPQLYPGGTGGVLSGPPMGP--- 235 Query: 187 KSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTR 246 + G + + + N G +HP PP + S Sbjct: 236 ------KGGGAASSVGGPNG---------------GKQHP-------PPTTPISVS---- 263 Query: 247 ADLGPGSPPWAVKTEAVSGDC-----PLQGLLHCLKELPEAQDRHP------SPSGVGNR 295 + G+PP T V G P H LP P SP G+G + Sbjct: 264 SSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQ 323 Query: 296 RLQ---ENPGAWKRGSGG------PGYLLTPPPH---PDLGAGGLLSVKMENSWVQSPPG 343 L +P A +G GG G L P PH P + ++ S S Sbjct: 324 PLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383 Query: 344 PASCQPGRQPLSPSATGDTRGVPQ-PSWGPEAQAASASSSPLEALEACL-------KGIP 395 AS S S ++ +P P P + S S+ P + + L +G P Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443 Query: 396 PNGSSPSQLPPTSCSQNPQPGDSRSQK---PELQPHRSHSEEATREPVLPLGLQSCVRD- 451 P L ++ P P + +Q P + H H ++ ++ Q + Sbjct: 444 PPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH 503 Query: 452 -GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS----PPGSSPLQGLENC 506 G S P P P SS P GS PPG + L Sbjct: 504 HGNSGPPPPGAFPHPLEGGSSHH--------AHPYAMSPSLGSLRPYPPGPAHL------ 549 Query: 507 LKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAP---- 562 P P + ++ S A GP + N ++ + C QG AP Sbjct: 550 ----PPPHSQVSY--SQAGPNGPPVSSSSN-SSSSTSQGSYPCSHPSPSQGPQGAPYPFP 602 Query: 563 -----TRSLHLVSPQVFTSSCVPACHQRGFKDPG-------ATRPGVWRWL-PEGSAP-- 607 T S +S + T + PA ++ PG A PG ++ P G P Sbjct: 603 PVPTVTTSSATLSTVIATVASSPAGYKTA-SPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 608 KPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPE-PDLWKPL 666 PS RG P G P+ P P + SG P P P PL Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721 Query: 667 --------PQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTA 718 P E P + PVP + P P S R G + Sbjct: 722 SATQIKQEPAEEYETP--ESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCAR 779 Query: 719 QD----PCPVSQL--------EKRPRVSEASRGLELGHGRPRVAAKTHER---------- 756 D P S+L EK R +E E R R K ER Sbjct: 780 SDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSV 839 Query: 757 -LLPQG--PPELPSESPPPELPPPEAAPPV 783 L +G P E PS P P PP E V Sbjct: 840 KLAQEGRAPVECPSLGPVPHRPPFEPGSAV 869 Score = 32.3 bits (72), Expect = 2.4 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 15/109 (13%) Query: 902 GLSRGTARRARP--------LPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAP---PAHPL 950 GLS+G AR P PPD+ P +P +S + S TP+ + AP P + Sbjct: 150 GLSQGPARPYHPPPLFPPSPQPPDSTPRQPE----ASFEPHPSVTPTGYHAPMEPPTSRM 205 Query: 951 LAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERP 999 G P P L P + PP +S P+G + P Sbjct: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254 Score = 31.2 bits (69), Expect = 5.3 Identities = 28/88 (31%), Positives = 36/88 (40%), Gaps = 10/88 (11%) Query: 915 PPDAPPAEPPGLHCSSSQQLLSSTP-SCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQG 973 PP APP P L+ + +LS P A + GG Q P PP P ++ G Sbjct: 209 PPGAPPPHPQ-LYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP-PPTTPISVSSSG 266 Query: 974 AS--PPAASADADVPTSGVAPDGIPERP 999 AS PP PT+ V +P P Sbjct: 267 ASGAPPTKP-----PTTPVGGGNLPSAP 289 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 62.8 bits (151), Expect = 2e-09 Identities = 192/809 (23%), Positives = 243/809 (30%), Gaps = 167/809 (20%) Query: 145 GDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPG 204 G G G P P P + GP + G+P P +S + ERG Sbjct: 899 GRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP-------- 950 Query: 205 NSPLQGLINCLKEILVPGPRHPETSPSF--LPPLPSLGTSRLTRADLGPGSPPWAVKTEA 262 N P QG PGP+ P P LP P + GP PP V + Sbjct: 951 NGP-QGPTG------FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQG 1003 Query: 263 VSGDC-PLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHP 321 +G+ P+ H P + P +G + P G PG P Sbjct: 1004 PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRG 1063 Query: 322 DLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASS 381 G G L +K N PPGPA R P + G P P GP A + Sbjct: 1064 LPGPVGALGLK-GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQ-GPPGPAGEKGA 1121 Query: 382 SPLEALEACLKGIPPNGSSPSQLP---PTSCSQNPQPGDSRSQKPELQPHRSHSEEATRE 438 + + P G Q P P PG+ + +P + S+ E Sbjct: 1122 PGEKGPQG------PAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGE 1175 Query: 439 PVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS----- 493 P GP+ P P G P S D + P G QG KG Sbjct: 1176 QGPP---------GPTGPQGPIGQP----GPSGADGE---PGPRGQQGLFGQKGDEGPRG 1219 Query: 494 ---PPGSSPLQGLENCLKEI-------------PVPVLRPAWPCSSAADRGPRRAEPRNW 537 PPG LQGL E P P+ + +GP Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279 Query: 538 TADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDP-GATRPG 596 ++G EA E G+G P ++G P GA P Sbjct: 1280 AVGEKGEPGEAGEPGLPGEGGPPGPKGERG----------------EKGESGPSGAAGPP 1323 Query: 597 VWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDP 656 + P PK SP P+ F GP P P G +G+D Sbjct: 1324 GPKGPPGDDGPKGSP--------------GPVGFPGDPGPPGEPGPAGQDGPPGDKGDDG 1369 Query: 657 RPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSG--GSPGEDPRRTEPRYCSGLG 714 P P P PS P P P G P G G G+ GE P +G Sbjct: 1370 EP-GQTGSPGPTGEPG-PSGPPGKRGPPGPAG-PEGRQGEKGAKGEAGLEGPPGKTGPIG 1426 Query: 715 AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPEL 774 P+ + G + G P P G LP SP P+ Sbjct: 1427 ----------------PQGAPGKPGPDGLRGIPG----------PVGEQGLPG-SPGPDG 1459 Query: 775 PPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQ 834 PP PP LP L K ++ L GL + Sbjct: 1460 PPGPMGPPGLP-------------------GLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500 Query: 835 VNRLGRRPQG-PGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGE 893 +R PQG GP G+ T P GP PG LP GP PK +G Sbjct: 1501 GDRGLPGPQGSSGPKGEQG--ITGPSGP--IGPPGPPGLP-----GPPGPK----GAKGS 1547 Query: 894 SCRAGDLQGLSRGTARRARPLPPDAPPAE 922 S G +G A P P PP E Sbjct: 1548 SGPTG-----PKGEAGHPGPPGPPGPPGE 1571 Score = 47.0 bits (110), Expect = 9e-05 Identities = 66/275 (24%), Positives = 87/275 (31%), Gaps = 61/275 (22%) Query: 122 DGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP-- 179 DGP P P D P G G P +P T GP G PP Sbjct: 1332 DGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391 Query: 180 --THSPSRRKSHRGQERGTSEAGI-----------------SPGNSPLQGLINCLKEILV 220 P+ + +G++ EAG+ PG L+G+ + E + Sbjct: 1392 RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGL 1451 Query: 221 PGPRHPETSPSFL--PPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKE 278 PG P+ P + P LP L + D GP + G L GL+ E Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGL------KGDSGP---------KGEKGHPGLIGLIGPPGE 1496 Query: 279 LPEAQDRH-PSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSW 337 E DR P P G + ++G GP + PP P L Sbjct: 1497 QGEKGDRGLPGPQGSSGPK-------GEQGITGPSGPIGPPGPPGL-------------- 1535 Query: 338 VQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGP 372 PPGP + P P G P P P Sbjct: 1536 -PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569 Score = 44.3 bits (103), Expect = 6e-04 Identities = 97/417 (23%), Positives = 132/417 (31%), Gaps = 68/417 (16%) Query: 142 GPTGD----GVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP-THSPSRRKSHRGQERGT 196 GP G G G+ PI +P P GP G P P+ R +G Sbjct: 1084 GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLP 1143 Query: 197 SEAGI--SPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPG-- 252 AG PG +G I + G + + P P +G + AD PG Sbjct: 1144 GPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPR 1203 Query: 253 ------------------SPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGN 294 PP V + + G +G + ++ P P G Sbjct: 1204 GQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM--GPPGPPGPRGPSG 1261 Query: 295 RRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPL 354 + P G G PG + + G GL PPGP + + Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGL-------PGEGGPPGPKGERGEKGES 1314 Query: 355 SPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQ 414 PS G P P P S P+ G P + P + P Q+ Sbjct: 1315 GPSGAA---GPPGPKGPPGDDGPKGSPGPV--------GFPGDPGPPGE--PGPAGQDGP 1361 Query: 415 PGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDW 474 PGD + + +P ++ S T EP P G + GP P P G + Sbjct: 1362 PGD---KGDDGEPGQTGSPGPTGEPG-PSGPPG--KRGPPGPAGPEGRQGEKGAKGEAGL 1415 Query: 475 DLDFG--SPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGP 529 + G P+G QG PGK P G L+ IP PV P S D P Sbjct: 1416 EGPPGKTGPIGPQGA-PGKPGPDG----------LRGIPGPVGEQGLPGSPGPDGPP 1461 Score = 41.2 bits (95), Expect = 0.005 Identities = 99/406 (24%), Positives = 128/406 (31%), Gaps = 77/406 (18%) Query: 97 GERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIK 156 GE+ A EP G+L P GP L P + GPTG G P Sbjct: 450 GEKGQKGEPAIIEP----GMLIEGPPGPEGPAGLPGPPG----TMGPTGQ--VGDP---- 495 Query: 157 TADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLK 216 ++ P R PGA G P T + G + G+ +S S Q ++ + Sbjct: 496 -GERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQAR 554 Query: 217 EILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCL 276 + + GP P L P GP PP + + GD QG Sbjct: 555 -LALRGP----AGPMGLTGRP------------GPVGPPGSGGLKGEPGDVGPQG----- 592 Query: 277 KELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENS 336 P P P+G RR + + G G P D G GL + E Sbjct: 593 ---PRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTG------PKGDRGFDGLAGLPGEKG 643 Query: 337 WVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPP 396 + PGP+ P P GD V GP L + P Sbjct: 644 H-RGDPGPSG--PPGPPGDDGERGDDGEV-----GPRGLPGEPGPRGL---------LGP 686 Query: 397 NGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRP 456 G PP + QPG + P+ +P + LP G Q + GP Sbjct: 687 KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLP-GPQGAI--GPPGE 743 Query: 457 LAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQG 502 P G P D P G HPGK PPG QG Sbjct: 744 KGPLGKP-GLPGMPGAD------GPPG----HPGKEGPPGEKGGQG 778 Score = 31.6 bits (70), Expect = 4.0 Identities = 49/184 (26%), Positives = 55/184 (29%), Gaps = 55/184 (29%) Query: 842 PQGP----GPMGQASWMWTLPRGPRWAHG-PGHR----HLPYWRQKGPTRPKPKILRGQG 892 PQGP GP G P GP G PGH + + GP P P ++ QG Sbjct: 953 PQGPTGFPGPKG--------PPGPPGKDGLPGHPGQRGETGFQGKTGPPGP-PGVVGPQG 1003 Query: 893 ESCRAGDLQGLSRGTARRARPLPPDAPPAE-----------------PPGLHCSSSQQLL 935 + G + R P PP PP E P GL L Sbjct: 1004 PTGETGPM-------GERGHPGPP-GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGL 1055 Query: 936 SSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGI 995 P P L G P PP PA S P P GI Sbjct: 1056 RGFPGDRGLPGPVGALGLKGNEGPPGPP------------GPAGSPGERGPAGAAGPIGI 1103 Query: 996 PERP 999 P RP Sbjct: 1104 PGRP 1107 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 61.6 bits (148), Expect = 4e-09 Identities = 176/758 (23%), Positives = 234/758 (30%), Gaps = 155/758 (20%) Query: 122 DGPTSQPHLATTPTDSSCSSGPTGD----GVQGSP-LPIKTADK--------PWPTRKEG 168 DGP P PT SG G+ GV G P P + K P ++G Sbjct: 822 DGPEG-PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 880 Query: 169 PGALGGEPSPP-THSPSRRKSHRGQE--------RGTSEAGISPGNSPLQGLINCLKEIL 219 + G+P P P+ + RG +GTS PG +G + Sbjct: 881 ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 940 Query: 220 VPGPRHPETSPSF--LPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLK 277 PGP+ P P LP P + GP P V + +G+ Sbjct: 941 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--------- 991 Query: 278 ELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSW 337 P + HP P G Q PGA +G G P P G G ++ Sbjct: 992 --PIGERGHPGPPGPPGE--QGLPGA----AGKEGAKGDPGPQGISGKDGPAGLR----- 1038 Query: 338 VQSPPGPASCQPGRQPLSPSATGD-TRGVPQPSWGPEAQAASASSSPLEALEACLKGIPP 396 PG PG Q G+ +G P P P + ++ ++ P+ G+P Sbjct: 1039 --GFPGERGL-PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI--------GLP- 1086 Query: 397 NGSSPSQLPPTSCSQNPQPGDSRSQKPELQ--------------PHRSHSEEATREPVLP 442 G Q PP + PG+ Q P + P S E+ + + Sbjct: 1087 -GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145 Query: 443 LGLQSCVRD-GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS-------- 493 G + D G + P P G + D + G P G QG KG Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG-PRGQQGMFGQKGDEGARGFPG 1204 Query: 494 PPGSSPLQGLENCLKEI----PVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEAC 549 PPG LQGL E V + P P +GP A+ G Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264 Query: 550 ESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKD----PGATRPGVWRWLPEGS 605 E G+ P + P+ +RG K PGA P + P Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPK----------GERGEKGEAGPPGAAGPPGAKGPPGDD 1314 Query: 606 APKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGED--------PR 657 PK +P P+ F GP P P G +GED P Sbjct: 1315 GPKGNP--------------GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360 Query: 658 PEPDLWKPLP------------QERDRLPSCKPPVPLSPCPGGT-PAGSSG--GSPGEDP 702 P + P P + R K PG T P G G G PG + Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1420 Query: 703 RRTEPRYC--SGLGAGTAQD--PCPVSQLEKRPRVSEASRGLELGH-------GRPRVAA 751 R P GL QD P P+ + E GH G P Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1480 Query: 752 KTHERLLP--QGPPELPSES--PPPELPPPEAAPPVLP 785 + +R LP QG P + P P P PP LP Sbjct: 1481 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1518 Score = 47.0 bits (110), Expect = 9e-05 Identities = 173/708 (24%), Positives = 213/708 (30%), Gaps = 146/708 (20%) Query: 28 PGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGAMDSPE 87 PG G GS +G+ GDP PR V+ P G P Sbjct: 552 PGPVGGPGSSGAKGES----GDPGPQGPRG----------VQGPP--------GPTGKPG 589 Query: 88 SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGD- 146 R + DG R P A+ GL P P + H GP GD Sbjct: 590 KRGRPGA-DGGRGMPGEPGAKGDRGFDGL----PGLPGDKGHRGERGPQGP--PGPPGDD 642 Query: 147 ---GVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP----THSPSRRKSHRGQERGTSEA 199 G G P + P GP G P P P K + G + Sbjct: 643 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 702 Query: 200 GISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVK 259 G GN QGL PGP+ P P P G + L AD PG P Sbjct: 703 G-QQGNPGPQGL---------PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP----G 748 Query: 260 TEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGV----GNRRLQENPGAWKRGSGGPGYLL 315 E SG+ G P+ +P P GV G R L+ + G K G PG+ Sbjct: 749 KEGQSGEKGALG-----PPGPQGPIGYPGPRGVKGADGVRGLKGSKGE-KGEDGFPGFKG 802 Query: 316 TPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQ 375 D G G + + E+ + P G A P + GVP P Q Sbjct: 803 DMGLKGDRGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 861 Query: 376 AASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEA 435 S+ G P + + + P P R Q+ P S Sbjct: 862 GPKGST-----------GFPGFPGANGEKGARGVAGKPGP---RGQRGPTGPRGSRGARG 907 Query: 436 TREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPP 495 P G DGP P RG + F P G G PGK P Sbjct: 908 PTGKPGPKGTSG--GDGPPGPPGERG-------PQGPQGPVGFPGPKGPPGP-PGKDGLP 957 Query: 496 GSSPLQGLENCLKEIPVP----VLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACES 551 G +G + P V+ P P G R ++GL A + Sbjct: 958 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1017 Query: 552 ARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKD----PGAT-RPGVWRWLPEGSA 606 G PQ + PA RGF PGA PG L G Sbjct: 1018 GAKGD------------PGPQGISGKDGPA-GLRGFPGERGLPGAQGAPG----LKGGEG 1060 Query: 607 PKPSPLHCLESALRGI--------LPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRP 658 P+ P RG LP RP GP P P G +G Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRP-------GPQGPPGPAGEKGAPGEKG----- 1108 Query: 659 EPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTE 706 PQ + PV L PG PAG + GSPGED + E Sbjct: 1109 --------PQGPAGRDGVQGPVGL---PG--PAGPA-GSPGEDGDKGE 1142 Score = 34.7 bits (78), Expect = 0.48 Identities = 69/284 (24%), Positives = 95/284 (33%), Gaps = 93/284 (32%) Query: 140 SSGPTGD-GVQGSPLPIKTADKPWPTRKEGPGALG------------GEPSPPTHS---- 182 + GP GD G +G+P P+ P P + GP G+P PP S Sbjct: 1307 AKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1366 Query: 183 ----PSRR--------KSHRGQERGTSEAGI-----------------SPGNSPLQGLIN 213 P +R + +G++ EAG PG L+G+ Sbjct: 1367 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1426 Query: 214 CLKEILVPGPRHPETSPSFL--PPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQG 271 + E +PG + P + P LP L + D PGS + G L G Sbjct: 1427 PVGEQGLPGAAGQDGPPGPMGPPGLPGL------KGD--PGS-------KGEKGHPGLIG 1471 Query: 272 LLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSG---GPGYLLTPPPHPDLGAGGL 328 L+ E E DR G Q +PGA +G G GP L PP P L Sbjct: 1472 LIGPPGEQGEKGDR-------GLPGTQGSPGA--KGDGGIPGPAGPLGPPGPPGL----- 1517 Query: 329 LSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGP 372 PGP + + P+ G+P P P Sbjct: 1518 -------------PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1548 Score = 32.3 bits (72), Expect = 2.4 Identities = 60/239 (25%), Positives = 73/239 (30%), Gaps = 43/239 (17%) Query: 122 DGPTSQPHLATTPTDSSCSS--GPTG-DGVQGS------------PLPIKTADKPWPTRK 166 DGP P P D GP G DGV G P P A P P K Sbjct: 1314 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1373 Query: 167 EGP-GALGGEPSPPTHSPSRRKSHRGQERGTSEAGIS-----PGNSPLQGLINCLKEILV 220 GP GA G E G T G PG L+G+ + E + Sbjct: 1374 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1433 Query: 221 PGPRHPETSPSFLPP--LPSLGTSRLTRADLG----------PGSP--------PWAVKT 260 PG + P + P LP L ++ + G PG P + Sbjct: 1434 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1493 Query: 261 EAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPP 319 GD + G L P P P G + P K SG PG +P P Sbjct: 1494 PGAKGDGGIPGPAGPLG--PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1550 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 61.6 bits (148), Expect = 4e-09 Identities = 176/758 (23%), Positives = 234/758 (30%), Gaps = 155/758 (20%) Query: 122 DGPTSQPHLATTPTDSSCSSGPTGD----GVQGSP-LPIKTADK--------PWPTRKEG 168 DGP P PT SG G+ GV G P P + K P ++G Sbjct: 771 DGPEG-PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 829 Query: 169 PGALGGEPSPP-THSPSRRKSHRGQE--------RGTSEAGISPGNSPLQGLINCLKEIL 219 + G+P P P+ + RG +GTS PG +G + Sbjct: 830 ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 889 Query: 220 VPGPRHPETSPSF--LPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLK 277 PGP+ P P LP P + GP P V + +G+ Sbjct: 890 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--------- 940 Query: 278 ELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSW 337 P + HP P G Q PGA +G G P P G G ++ Sbjct: 941 --PIGERGHPGPPGPPGE--QGLPGA----AGKEGAKGDPGPQGISGKDGPAGLR----- 987 Query: 338 VQSPPGPASCQPGRQPLSPSATGD-TRGVPQPSWGPEAQAASASSSPLEALEACLKGIPP 396 PG PG Q G+ +G P P P + ++ ++ P+ G+P Sbjct: 988 --GFPGERGL-PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI--------GLP- 1035 Query: 397 NGSSPSQLPPTSCSQNPQPGDSRSQKPELQ--------------PHRSHSEEATREPVLP 442 G Q PP + PG+ Q P + P S E+ + + Sbjct: 1036 -GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094 Query: 443 LGLQSCVRD-GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS-------- 493 G + D G + P P G + D + G P G QG KG Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG-PRGQQGMFGQKGDEGARGFPG 1153 Query: 494 PPGSSPLQGLENCLKEI----PVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEAC 549 PPG LQGL E V + P P +GP A+ G Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213 Query: 550 ESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKD----PGATRPGVWRWLPEGS 605 E G+ P + P+ +RG K PGA P + P Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPK----------GERGEKGEAGPPGAAGPPGAKGPPGDD 1263 Query: 606 APKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGED--------PR 657 PK +P P+ F GP P P G +GED P Sbjct: 1264 GPKGNP--------------GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309 Query: 658 PEPDLWKPLP------------QERDRLPSCKPPVPLSPCPGGT-PAGSSG--GSPGEDP 702 P + P P + R K PG T P G G G PG + Sbjct: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1369 Query: 703 RRTEPRYC--SGLGAGTAQD--PCPVSQLEKRPRVSEASRGLELGH-------GRPRVAA 751 R P GL QD P P+ + E GH G P Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429 Query: 752 KTHERLLP--QGPPELPSES--PPPELPPPEAAPPVLP 785 + +R LP QG P + P P P PP LP Sbjct: 1430 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1467 Score = 47.0 bits (110), Expect = 9e-05 Identities = 173/708 (24%), Positives = 213/708 (30%), Gaps = 146/708 (20%) Query: 28 PGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGAMDSPE 87 PG G GS +G+ GDP PR V+ P G P Sbjct: 501 PGPVGGPGSSGAKGES----GDPGPQGPRG----------VQGPP--------GPTGKPG 538 Query: 88 SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGD- 146 R + DG R P A+ GL P P + H GP GD Sbjct: 539 KRGRPGA-DGGRGMPGEPGAKGDRGFDGL----PGLPGDKGHRGERGPQGP--PGPPGDD 591 Query: 147 ---GVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP----THSPSRRKSHRGQERGTSEA 199 G G P + P GP G P P P K + G + Sbjct: 592 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 651 Query: 200 GISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVK 259 G GN QGL PGP+ P P P G + L AD PG P Sbjct: 652 G-QQGNPGPQGL---------PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP----G 697 Query: 260 TEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGV----GNRRLQENPGAWKRGSGGPGYLL 315 E SG+ G P+ +P P GV G R L+ + G K G PG+ Sbjct: 698 KEGQSGEKGALG-----PPGPQGPIGYPGPRGVKGADGVRGLKGSKGE-KGEDGFPGFKG 751 Query: 316 TPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQ 375 D G G + + E+ + P G A P + GVP P Q Sbjct: 752 DMGLKGDRGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 810 Query: 376 AASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEA 435 S+ G P + + + P P R Q+ P S Sbjct: 811 GPKGST-----------GFPGFPGANGEKGARGVAGKPGP---RGQRGPTGPRGSRGARG 856 Query: 436 TREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPP 495 P G DGP P RG + F P G G PGK P Sbjct: 857 PTGKPGPKGTSG--GDGPPGPPGERG-------PQGPQGPVGFPGPKGPPGP-PGKDGLP 906 Query: 496 GSSPLQGLENCLKEIPVP----VLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACES 551 G +G + P V+ P P G R ++GL A + Sbjct: 907 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 966 Query: 552 ARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKD----PGAT-RPGVWRWLPEGSA 606 G PQ + PA RGF PGA PG L G Sbjct: 967 GAKGD------------PGPQGISGKDGPA-GLRGFPGERGLPGAQGAPG----LKGGEG 1009 Query: 607 PKPSPLHCLESALRGI--------LPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRP 658 P+ P RG LP RP GP P P G +G Sbjct: 1010 PQGPPGPVGSPGERGSAGTAGPIGLPGRP-------GPQGPPGPAGEKGAPGEKG----- 1057 Query: 659 EPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTE 706 PQ + PV L PG PAG + GSPGED + E Sbjct: 1058 --------PQGPAGRDGVQGPVGL---PG--PAGPA-GSPGEDGDKGE 1091 Score = 34.7 bits (78), Expect = 0.48 Identities = 69/284 (24%), Positives = 95/284 (33%), Gaps = 93/284 (32%) Query: 140 SSGPTGD-GVQGSPLPIKTADKPWPTRKEGPGALG------------GEPSPPTHS---- 182 + GP GD G +G+P P+ P P + GP G+P PP S Sbjct: 1256 AKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1315 Query: 183 ----PSRR--------KSHRGQERGTSEAGI-----------------SPGNSPLQGLIN 213 P +R + +G++ EAG PG L+G+ Sbjct: 1316 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1375 Query: 214 CLKEILVPGPRHPETSPSFL--PPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQG 271 + E +PG + P + P LP L + D PGS + G L G Sbjct: 1376 PVGEQGLPGAAGQDGPPGPMGPPGLPGL------KGD--PGS-------KGEKGHPGLIG 1420 Query: 272 LLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSG---GPGYLLTPPPHPDLGAGGL 328 L+ E E DR G Q +PGA +G G GP L PP P L Sbjct: 1421 LIGPPGEQGEKGDR-------GLPGTQGSPGA--KGDGGIPGPAGPLGPPGPPGL----- 1466 Query: 329 LSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGP 372 PGP + + P+ G+P P P Sbjct: 1467 -------------PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497 Score = 32.3 bits (72), Expect = 2.4 Identities = 60/239 (25%), Positives = 73/239 (30%), Gaps = 43/239 (17%) Query: 122 DGPTSQPHLATTPTDSSCSS--GPTG-DGVQGS------------PLPIKTADKPWPTRK 166 DGP P P D GP G DGV G P P A P P K Sbjct: 1263 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1322 Query: 167 EGP-GALGGEPSPPTHSPSRRKSHRGQERGTSEAGIS-----PGNSPLQGLINCLKEILV 220 GP GA G E G T G PG L+G+ + E + Sbjct: 1323 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1382 Query: 221 PGPRHPETSPSFLPP--LPSLGTSRLTRADLG----------PGSP--------PWAVKT 260 PG + P + P LP L ++ + G PG P + Sbjct: 1383 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1442 Query: 261 EAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPP 319 GD + G L P P P G + P K SG PG +P P Sbjct: 1443 PGAKGDGGIPGPAGPLG--PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 61.6 bits (148), Expect = 4e-09 Identities = 176/758 (23%), Positives = 234/758 (30%), Gaps = 155/758 (20%) Query: 122 DGPTSQPHLATTPTDSSCSSGPTGD----GVQGSP-LPIKTADK--------PWPTRKEG 168 DGP P PT SG G+ GV G P P + K P ++G Sbjct: 810 DGPEG-PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 868 Query: 169 PGALGGEPSPP-THSPSRRKSHRGQE--------RGTSEAGISPGNSPLQGLINCLKEIL 219 + G+P P P+ + RG +GTS PG +G + Sbjct: 869 ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 928 Query: 220 VPGPRHPETSPSF--LPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLK 277 PGP+ P P LP P + GP P V + +G+ Sbjct: 929 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--------- 979 Query: 278 ELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSW 337 P + HP P G Q PGA +G G P P G G ++ Sbjct: 980 --PIGERGHPGPPGPPGE--QGLPGA----AGKEGAKGDPGPQGISGKDGPAGLR----- 1026 Query: 338 VQSPPGPASCQPGRQPLSPSATGD-TRGVPQPSWGPEAQAASASSSPLEALEACLKGIPP 396 PG PG Q G+ +G P P P + ++ ++ P+ G+P Sbjct: 1027 --GFPGERGL-PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI--------GLP- 1074 Query: 397 NGSSPSQLPPTSCSQNPQPGDSRSQKPELQ--------------PHRSHSEEATREPVLP 442 G Q PP + PG+ Q P + P S E+ + + Sbjct: 1075 -GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133 Query: 443 LGLQSCVRD-GPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGS-------- 493 G + D G + P P G + D + G P G QG KG Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG-PRGQQGMFGQKGDEGARGFPG 1192 Query: 494 PPGSSPLQGLENCLKEI----PVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEAC 549 PPG LQGL E V + P P +GP A+ G Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1252 Query: 550 ESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKD----PGATRPGVWRWLPEGS 605 E G+ P + P+ +RG K PGA P + P Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPK----------GERGEKGEAGPPGAAGPPGAKGPPGDD 1302 Query: 606 APKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGED--------PR 657 PK +P P+ F GP P P G +GED P Sbjct: 1303 GPKGNP--------------GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348 Query: 658 PEPDLWKPLP------------QERDRLPSCKPPVPLSPCPGGT-PAGSSG--GSPGEDP 702 P + P P + R K PG T P G G G PG + Sbjct: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1408 Query: 703 RRTEPRYC--SGLGAGTAQD--PCPVSQLEKRPRVSEASRGLELGH-------GRPRVAA 751 R P GL QD P P+ + E GH G P Sbjct: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468 Query: 752 KTHERLLP--QGPPELPSES--PPPELPPPEAAPPVLP 785 + +R LP QG P + P P P PP LP Sbjct: 1469 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1506 Score = 47.0 bits (110), Expect = 9e-05 Identities = 173/708 (24%), Positives = 213/708 (30%), Gaps = 146/708 (20%) Query: 28 PGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGAMDSPE 87 PG G GS +G+ GDP PR V+ P G P Sbjct: 540 PGPVGGPGSSGAKGES----GDPGPQGPRG----------VQGPP--------GPTGKPG 577 Query: 88 SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGD- 146 R + DG R P A+ GL P P + H GP GD Sbjct: 578 KRGRPGA-DGGRGMPGEPGAKGDRGFDGL----PGLPGDKGHRGERGPQGP--PGPPGDD 630 Query: 147 ---GVQGSPLPIKTADKPWPTRKEGPGALGGEPSPP----THSPSRRKSHRGQERGTSEA 199 G G P + P GP G P P P K + G + Sbjct: 631 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 690 Query: 200 GISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVK 259 G GN QGL PGP+ P P P G + L AD PG P Sbjct: 691 G-QQGNPGPQGL---------PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP----G 736 Query: 260 TEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGV----GNRRLQENPGAWKRGSGGPGYLL 315 E SG+ G P+ +P P GV G R L+ + G K G PG+ Sbjct: 737 KEGQSGEKGALG-----PPGPQGPIGYPGPRGVKGADGVRGLKGSKGE-KGEDGFPGFKG 790 Query: 316 TPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQ 375 D G G + + E+ + P G A P + GVP P Q Sbjct: 791 DMGLKGDRGEVGQIGPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 849 Query: 376 AASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEA 435 S+ G P + + + P P R Q+ P S Sbjct: 850 GPKGST-----------GFPGFPGANGEKGARGVAGKPGP---RGQRGPTGPRGSRGARG 895 Query: 436 TREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPP 495 P G DGP P RG + F P G G PGK P Sbjct: 896 PTGKPGPKGTSG--GDGPPGPPGERG-------PQGPQGPVGFPGPKGPPGP-PGKDGLP 945 Query: 496 GSSPLQGLENCLKEIPVP----VLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACES 551 G +G + P V+ P P G R ++GL A + Sbjct: 946 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1005 Query: 552 ARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKD----PGAT-RPGVWRWLPEGSA 606 G PQ + PA RGF PGA PG L G Sbjct: 1006 GAKGD------------PGPQGISGKDGPA-GLRGFPGERGLPGAQGAPG----LKGGEG 1048 Query: 607 PKPSPLHCLESALRGI--------LPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRP 658 P+ P RG LP RP GP P P G +G Sbjct: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRP-------GPQGPPGPAGEKGAPGEKG----- 1096 Query: 659 EPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTE 706 PQ + PV L PG PAG + GSPGED + E Sbjct: 1097 --------PQGPAGRDGVQGPVGL---PG--PAGPA-GSPGEDGDKGE 1130 Score = 34.7 bits (78), Expect = 0.48 Identities = 69/284 (24%), Positives = 95/284 (33%), Gaps = 93/284 (32%) Query: 140 SSGPTGD-GVQGSPLPIKTADKPWPTRKEGPGALG------------GEPSPPTHS---- 182 + GP GD G +G+P P+ P P + GP G+P PP S Sbjct: 1295 AKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1354 Query: 183 ----PSRR--------KSHRGQERGTSEAGI-----------------SPGNSPLQGLIN 213 P +R + +G++ EAG PG L+G+ Sbjct: 1355 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1414 Query: 214 CLKEILVPGPRHPETSPSFL--PPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQG 271 + E +PG + P + P LP L + D PGS + G L G Sbjct: 1415 PVGEQGLPGAAGQDGPPGPMGPPGLPGL------KGD--PGS-------KGEKGHPGLIG 1459 Query: 272 LLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSG---GPGYLLTPPPHPDLGAGGL 328 L+ E E DR G Q +PGA +G G GP L PP P L Sbjct: 1460 LIGPPGEQGEKGDR-------GLPGTQGSPGA--KGDGGIPGPAGPLGPPGPPGL----- 1505 Query: 329 LSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGP 372 PGP + + P+ G+P P P Sbjct: 1506 -------------PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536 Score = 32.3 bits (72), Expect = 2.4 Identities = 60/239 (25%), Positives = 73/239 (30%), Gaps = 43/239 (17%) Query: 122 DGPTSQPHLATTPTDSSCSS--GPTG-DGVQGS------------PLPIKTADKPWPTRK 166 DGP P P D GP G DGV G P P A P P K Sbjct: 1302 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1361 Query: 167 EGP-GALGGEPSPPTHSPSRRKSHRGQERGTSEAGIS-----PGNSPLQGLINCLKEILV 220 GP GA G E G T G PG L+G+ + E + Sbjct: 1362 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1421 Query: 221 PGPRHPETSPSFLPP--LPSLGTSRLTRADLG----------PGSP--------PWAVKT 260 PG + P + P LP L ++ + G PG P + Sbjct: 1422 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1481 Query: 261 EAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPP 319 GD + G L P P P G + P K SG PG +P P Sbjct: 1482 PGAKGDGGIPGPAGPLG--PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538 >gi|188536004 zinc finger protein 469 [Homo sapiens] Length = 3925 Score = 61.6 bits (148), Expect = 4e-09 Identities = 247/1111 (22%), Positives = 350/1111 (31%), Gaps = 202/1111 (18%) Query: 28 PGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEI-PEFLFG-EVKGAMDS 85 P R++ G+ A EG C D P+ L + + +E P F E K + Sbjct: 1146 PSRSLETGAAAREGGPK--CADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETA 1203 Query: 86 PESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSS--CSSGP 143 ES SP AA A E GLL +P+ P H TP S ++ P Sbjct: 1204 EESAPDSTEFTEALRSPPAACAGEMGASPGLL--IPEQPPPSRHDTGTPKPSGSLANTAP 1261 Query: 144 TGD-----------GVQGSPLPIKTADKPWPTRKEGP----------------------- 169 G G G+ P+ K P R+ G Sbjct: 1262 HGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKI 1321 Query: 170 GALGGEPS----PPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRH 225 + G +P+ P P +K + SE + P + L C E L P P Sbjct: 1322 SSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP-----KDLAGCFLEELHPKPSA 1376 Query: 226 PETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTE-AVSGDCPLQGLLHCLKELPEAQD 284 + P+ L G + P SPP +TE + P +LP + Sbjct: 1377 RDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRF 1436 Query: 285 RHPSPSGVGNRRLQENPGAW-----KRGSGGPGYL----------LTPPPHPDLGAGGLL 329 P + R P A K P Y + P PDL G +L Sbjct: 1437 DPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVL 1496 Query: 330 SVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEA 389 S ++ P + PG +PS G G ++ + LE+ Sbjct: 1497 S--------KTCPPERTVVPGA---APSLPGKGSGCSVALMSHLSEDELEIQKLVTELES 1545 Query: 390 CLKGIPPNGSSPSQLPPTSCSQNPQPG---DSRSQKPELQPHRSHSEEATREPVLPLGLQ 446 L+ +P +L + G + SQ+ Q H + + + +G Sbjct: 1546 QLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGES 1605 Query: 447 SCVRDGPSRPLA--------PRGT---PTSFSSSSST-----DWDLDFGSPVGNQGQH-- 488 + R+G +A P GT P SF + DL G+P +G + Sbjct: 1606 TAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFH 1665 Query: 489 -----PGKGSPPGSSPLQG-----LENCLKEI---PVPVLRPAWPCSSAADRG---PRRA 532 S G +G + CL E P P L + D+ P+ Sbjct: 1666 FQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNK 1725 Query: 533 EPRNWTADKEGLRAEACESARLG----QGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFK 588 E + ++ LR CE R G G + P R +P+ F S V F+ Sbjct: 1726 EAASSQESEDSLRLLPCEQ-RGGFLPEPGTADQPHRGAP--APEAFGSPAVHLAPDLAFQ 1782 Query: 589 DPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSF 648 GA P + P G++P + G L R G +P +SS Sbjct: 1783 GDGA--PPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEF---APAGASSL 1837 Query: 649 SGSEGED----PRPEPD-LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPG---- 699 + G + P P P + P R + P+ PP+ PG A S G G Sbjct: 1838 TAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQEL 1897 Query: 700 ----EDPRRTEPRYCSG-------LGAGTAQDPCPVSQLEKRPRVSEASRGLEL-GH-GR 746 + P R P G + G AQ Q+ P V+ GLE GH G Sbjct: 1898 TPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGL 1957 Query: 747 PRVAAKTHERLLPQGPPEL--PSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELH 804 A KT QG P P A+ P ++L P Sbjct: 1958 LGQAEKTQG----QGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTE---------- 2003 Query: 805 SLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWA 864 GA L EK A++ + T P P P ++ L A Sbjct: 2004 --GAVLLEKCKGSRAAMSLQEEAEPT-----------PSPPSPNRES-----LALALTAA 2045 Query: 865 HG-PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR------PLPPD 917 H G R P KP + G + GDL + A PLP + Sbjct: 2046 HSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPRE 2105 Query: 918 APPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPP 977 P P QL +S PSC P LLA + PA PL+ A Sbjct: 2106 DPLTSPSRAQGGLGGQLPAS-PSCRDPPGPQQLLACS-----------PAWAPLEEADGV 2153 Query: 978 AASADADVPTSGVAPDGIPERPKEPSSLLGG 1008 A+ D S VAP + P +P L G Sbjct: 2154 QATTDTGAEDSPVAPPSLTTSPCDPKEALAG 2184 Score = 58.5 bits (140), Expect = 3e-08 Identities = 175/745 (23%), Positives = 234/745 (31%), Gaps = 175/745 (23%) Query: 338 VQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASA-SSSPLEALEACLKGIPP 396 V S PG S QP + +P AT T+G + G +AQA + P +A + LK Sbjct: 23 VASSPGHPS-QPPLEDNTP-ATRTTKGAREA--GGQAQAMELPEAQPRQARDGELKPPSL 78 Query: 397 NGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRP 456 G +PS P S PG S Q P R+ R LG+ S R P+ Sbjct: 79 RGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQR---YILGIASS-RTKPTLD 134 Query: 457 LAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLR 516 P + D G+ + P + P + L G C +E P Sbjct: 135 ETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEEL-GFHRCFQEPPSSFTS 193 Query: 517 PAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTS 576 + SA R P P Q RG +P + Q + Sbjct: 194 TNYTSPSATPRPPAPGPP---------------------QSRGTSPLQPGSYPEYQASGA 232 Query: 577 SCVPACHQRGFKDPGA---TRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACV 633 P + F PGA P +P+GS P SP RG+ P F + Sbjct: 233 DSWPPAAENSF--PGANFGVPPAEPEPIPKGSRPGGSP--------RGVSFQFP--FPAL 280 Query: 634 GGPSPSPSPGSSS-----------SFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPL 682 G S P P + +F +G P P LP+ P PL Sbjct: 281 HGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-----LPTQPAPSPL 335 Query: 683 SPCPGGTPAG-----------SSGGSPGEDPR---------------RTEPRYCSGLGAG 716 PC G P G SS G+ PR P GLG+ Sbjct: 336 -PCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGST 394 Query: 717 TAQDPCPVSQLEKRPRVSEASR--GLELGHGRPRVAAKTHERLLPQGPP--ELPSESPPP 772 P S L +R +A R G++ G P L GPP LP P Sbjct: 395 RG----PPSSLPQRHFPGQAYRASGVDTSPGPP------DTELAAPGPPPARLPQLWDPT 444 Query: 773 ELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMR 832 P P PP P ++ + G+P + ++L +A Q + T R Sbjct: 445 AAPYP--TPPGGPLAATRSMFFNGQP----------SPGQRLCLPQSAPLPWPQVLPTAR 492 Query: 833 TQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQG 892 + + + P P G GP W G + GP P + QG Sbjct: 493 PSPHGMEMLSRLPFPAG----------GPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG 542 Query: 893 ESCRAGDLQGLS------------------RGTARRARPLPPDAPPAEPP---------G 925 S G++ GT P A P+E P G Sbjct: 543 GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAG 602 Query: 926 LHCSSSQQLLSST---------------PSCHAAPPAHPLLAHTGGHQSPLP-PLVPAAL 969 CSS + SS PS PP HP TG SP P P P +L Sbjct: 603 STCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHP--QETG---SPFPSPEPPHSL 657 Query: 970 PLQGASPPAASADADVPTSGVAPDG 994 P PA + P G+ +G Sbjct: 658 PTHYQPEPAKA--FPFPADGLGAEG 680 Score = 56.2 bits (134), Expect = 2e-07 Identities = 226/959 (23%), Positives = 311/959 (32%), Gaps = 207/959 (21%) Query: 82 AMDSPESESRGASLDGERAS------PEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPT 135 A+ + S S ERAS P A P P G L+ PTS H+ Sbjct: 2041 ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMP---- 2096 Query: 136 DSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGE--PSPPTHSPSRRKSHRGQE 193 CS GP LP + P + G LGG+ SP P Sbjct: 2097 ---CSLGP---------LP---REDPLTSPSRAQGGLGGQLPASPSCRDP---------- 2131 Query: 194 RGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGS 253 PG Q L+ C SP++ P + G T D G Sbjct: 2132 ---------PGP---QQLLAC--------------SPAWAPLEEADGVQATT--DTGAED 2163 Query: 254 PPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGY 313 P A + S P + L CL + G E+P +W GS Sbjct: 2164 SPVAPPSLTTSPCDPKEALAGCLLQ--------------GEGSPLEDPSSWPPGSVSA-- 2207 Query: 314 LLTPPPHPDLGAGGLLSV----KMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPS 369 +T D L + + E W PG A+ P +SPS G+ Sbjct: 2208 -VTCTHSGDTPKDSTLRIPEDSRKEKLW--ESPGRATSPPLAGAVSPSVAVRATGLSSTP 2264 Query: 370 WGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHR 429 G EAQA P + +G PP+ ++P ++P S +P S L HR Sbjct: 2265 TGDEAQAGRGLPGP----DPQSRGAPPH-TNPDRMPRGHSSYSP------SNTARL-GHR 2312 Query: 430 SHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHP 489 + T P P LQ GP P G +S+ D G+P G+ Sbjct: 2313 -EGQAVTAVPTEPPTLQGA---GPDSPACLEG-----EMGTSSKEPEDPGTP--ETGRSG 2361 Query: 490 GKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEA- 548 P + P GL P S + R P+ + L+ + Sbjct: 2362 ATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSR 2421 Query: 549 -----CESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPE 603 S GQ +G+AP + T A + G PG +R + P Sbjct: 2422 GYKKKPASTENGQWKGQAPHGPV--------TCEVCAASFRSG---PGLSRHKARKHRPH 2470 Query: 604 GSAP-KPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGED-PRPEPD 661 AP +PSP +AL P+ PL C P S SG E + R +P Sbjct: 2471 PGAPAEPSP-----AALPAQQPLEPLAQKC------QPPRKKSHRVSGKERPNHSRGDPS 2519 Query: 662 -LWKPLP----QERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAG 716 + +P P +E R P L P P T +P PR + R Sbjct: 2520 HVTQPPPAQGSKEVLRAPGSPHSQQLHP-PSPTEHEVDVKTPASKPRPDQAR-------- 2570 Query: 717 TAQDPCPVSQLEKR--------PRVSEASRG---LELGHGRPRVAAKTHERLLPQGPPEL 765 +D Q EKR P V S G+ R E +LP + Sbjct: 2571 --EDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVI 2628 Query: 766 PSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLA 825 + P AS P HC + A E+ RLAT G+ Sbjct: 2629 SDGR--------GSRPSPAMASYAASPSHC-----LSVEGGPEADGEQPPRLATLGPGVM 2675 Query: 826 QEVATMRTQVNRLG----RRPQG-----PGPMGQASWMWTLPRGPRWAHGPGHRHLPYWR 876 + A + G ++P G PG M A+ + P G + A G +W Sbjct: 2676 EGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAA-LGEQPTGQKGASARG-----FW- 2728 Query: 877 QKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPL-PPDAPPAEPPGLHCSSSQQLL 935 GP K + + S A D SR +R + + PP P G +SS Sbjct: 2729 --GPRETKALGVCKESGSEPAED---SSRAHSRSEEGVWEENTPPLGPLGFPETSSSPAD 2783 Query: 936 SSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDG 994 S+T SC P +P GG Q P P A+ A P + D +V S + P G Sbjct: 2784 STTSSCLQGLPDNP--DTQGGVQGPEGPTPDAS--GSSAKDPPSLFDDEVSFSQLFPPG 2838 Score = 48.9 bits (115), Expect = 2e-05 Identities = 223/1003 (22%), Positives = 308/1003 (30%), Gaps = 218/1003 (21%) Query: 123 GPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTAD---------KPWPTRKEGPGALG 173 G SQP L + + G G Q + + A KP R + P + Sbjct: 28 GHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTP 87 Query: 174 GEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINC-LKEILVPGPRHPETSPSF 232 G+ P +P R + R A SP + G+ + K L P +P+ + Sbjct: 88 GKRGSP-QTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146 Query: 233 LPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEA--QDRHPSPS 290 LP + + T A L PG P +TEA L G C +E P + + SPS Sbjct: 147 LPEVDT-PQGPGTGAPLRPGLP----RTEAQPAAEEL-GFHRCFQEPPSSFTSTNYTSPS 200 Query: 291 GVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPG 350 TP P PGP + G Sbjct: 201 A------------------------TPRP--------------------PAPGPPQSR-G 215 Query: 351 RQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPP-------NGSSPSQ 403 PL P + + + SW P A+ + ++ G+PP GS P Sbjct: 216 TSPLQPGSYPEYQASGADSWPPAAENSFPGAN---------FGVPPAEPEPIPKGSRPGG 266 Query: 404 LPPTSCSQNPQPG-DSRSQKPELQPHRSHSEEATREPVL-----PLGL--QSCVRDGPSR 455 P Q P P S KP H+ T P++ P G + V GP+ Sbjct: 267 SPRGVSFQFPFPALHGASTKPFPADVAGHA--FTNGPLVFAFHQPQGAWPEEAVGTGPAY 324 Query: 456 PLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 PL + P+ L+ S + PG L L +I +P Sbjct: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKI-LPER 383 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----GEAPTRSLHLVS 570 P+ + RGP + P+ + RA +++ G P R L Sbjct: 384 PPSAQDGLGSTRGPPSSLPQRHFPG-QAYRASGVDTSPGPPDTELAAPGPPPARLPQLWD 442 Query: 571 PQVF---TSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSP--LHCLESALRGILPV 625 P T P R G PG LP+ SAP P P L + G+ + Sbjct: 443 PTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQ-SAPLPWPQVLPTARPSPHGMEML 501 Query: 626 RPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPC 685 L F GGP G S G+ G+ P P R++LP+ + SP Sbjct: 502 SRLPFPA-GGPEWQ---GGSQGALGTAGKTPGP-----------REKLPAVRSSQGGSPA 546 Query: 686 -------------------------PGGTPAGSS----GGSPGEDPRRTEPRYCSGLGAG 716 P GTP+ G SP E P P + Sbjct: 547 LFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPL---PSPATNTAGS 603 Query: 717 TAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQ--GPPELPSESPPPEL 774 T P+S P E+ LG +A H PQ G P PS PP L Sbjct: 604 TCSSLSPMSSSPANPSSEESQLPGPLGP-----SAFFHPPTHPQETGSP-FPSPEPPHSL 657 Query: 775 P------PPEAAP------------------------PVLPASSLQPPCHCGKPLQQELH 804 P P +A P P + LQ P Sbjct: 658 PTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHF 717 Query: 805 SLGAALAEKLDRLATA------LAGLAQEVATMRTQVNRLGRRPQG----PGPMGQASWM 854 SL +A ++LD L T + LA +A + L R G PGP G S Sbjct: 718 SLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPP 777 Query: 855 WTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPL 914 PR P AH H + G + + G+ + R G L L A PL Sbjct: 778 -AAPRVPADAHAGLLSHAKTFLLAGDAQAE-----GKDDPLRTGFLPSL----AATPFPL 827 Query: 915 PPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAA------ 968 P E S + L+ P + P P P++ Sbjct: 828 PASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKS 887 Query: 969 ----LPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLG 1007 P A PP +A D T G P R + + LG Sbjct: 888 KAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLG 930 Score = 40.8 bits (94), Expect = 0.007 Identities = 177/799 (22%), Positives = 239/799 (29%), Gaps = 177/799 (22%) Query: 82 AMDSPESESRGA----------------SLDGERASPEAAAAREPCPLRGLLSCLPDGPT 125 AM+ PE++ R A S G+R SP+ R P L+ +G Sbjct: 57 AMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSP 116 Query: 126 SQPHL---ATTPTDSSCSSGPTGDGVQGSPLP-IKTADKPWPTRKEGPGALGGEPSPPTH 181 Q ++ A++ T + P ++ + LP + T P PG E P Sbjct: 117 PQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176 Query: 182 S----------PSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPS 231 PS S + +PG +G L PG +PE S Sbjct: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGT-----SPLQPGS-YPEYQAS 230 Query: 232 FLPPLPSLGTSRLTRADLG-PGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPS 290 P + A+ G P + P + + G P P P+ Sbjct: 231 GADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPA 290 Query: 291 GVGNRRLQENP---------GAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSP 341 V P GAW + G G P P Sbjct: 291 DVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQP-------------------A 331 Query: 342 PGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPN---G 398 P P C G QP + D G + S S ++L L PP+ G Sbjct: 332 PSPLPCYQG-QPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDG 390 Query: 399 SSPSQLPPTSCSQNPQPGDS-RSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPL 457 ++ PP+S Q PG + R+ + P +E A P P + D + P Sbjct: 391 LGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP--PPARLPQLWDPTAAPY 448 Query: 458 -APRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSP-------PGSSPLQGLENCLKE 509 P G P + + S + G P Q + +P P + P L Sbjct: 449 PTPPGGPLAATRSMFFN-----GQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 Query: 510 IPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLV 569 +P P P W S G TA K E + R QG Sbjct: 504 LPFPAGGPEWQGGSQGALG---------TAGKTPGPREKLPAVRSSQGG----------- 543 Query: 570 SPQVFTSSCVPACHQRGFKDPGA-------TRPGVWRWLPEGSAPKPSPLHCLESALRGI 622 SP +FT + G DPGA +P V P G+ P P S Sbjct: 544 SPALFTYN--------GMTDPGAQPLFFGVAQPQV---SPHGTPSLPPPRVVGASPSESP 592 Query: 623 LPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPL 682 LP A G S SP SSS + S E P P L P P Sbjct: 593 LPSPATNTA--GSTCSSLSPMSSSPANPSSEESQLPGP-----LGPSAFFHPPTHPQETG 645 Query: 683 SPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTA-----QDPCPVSQ-------LEKR 730 SP P P S +P + P GLGA A + P P L+ Sbjct: 646 SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705 Query: 731 PRV---------SEASRGLE---------------------LGH----GRPRVAAKTHER 756 PR S +S L+ L H G AK + Sbjct: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765 Query: 757 LLPQGPPELPSESPPPELP 775 P GPP LPS P +P Sbjct: 766 RSP-GPPGLPSPPAAPRVP 783 Score = 40.8 bits (94), Expect = 0.007 Identities = 160/696 (22%), Positives = 222/696 (31%), Gaps = 134/696 (19%) Query: 84 DSPESESRGASL--DGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSS 141 D+PE +S + D E + P ++ P L+ P+ P A TP + Sbjct: 856 DNPEIDSSFIDVFADEEPSGPRGPSSGHP--LKSKAGVTPESKAPPPLPAATPDPQTPRP 913 Query: 142 GPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQE-------- 193 G G +G P KT +LG P+ R+ RG++ Sbjct: 914 GDRGCPARGRP---KTR------------SLGLAPTEADAPSQGRQQRRGKQLKLFRKDL 958 Query: 194 --RGTSEAGISPGNSPLQGL----INCLKEILVPGPRHPETSP--SFLPPLPSL------ 239 G +E S G GL + L E P PR P T S P P + Sbjct: 959 DSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAAL 1018 Query: 240 --GTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKE----------LPEAQDRHP 287 T R L P P K +A G + +L +++ +D P Sbjct: 1019 PEETRSSRRRRLPPRKDP--RKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQP 1076 Query: 288 SPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSP-----P 342 P G G R G RG LT P D + + E +P P Sbjct: 1077 PPRGPGFR------GRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEP 1130 Query: 343 GPASCQPGRQPLSPSATGDTR----GVPQPSWGPEAQAASASSSPLEALEACLKGIPPNG 398 G + PGR SP A G +R G GP+ A S +P + L+ +P N Sbjct: 1131 GGSRPGPGR---SPQARGPSRSLETGAAAREGGPKC-ADRPSVAPKDPLQ-----VPTNT 1181 Query: 399 SSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDG---PSR 455 + + P+ PQ E P + EA R P + G P + Sbjct: 1182 ETSEETRPS--LDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQ 1239 Query: 456 PLAPR---GTP---------TSFSSSSSTDWDLDFGSPVGNQG--QHPGKGSP---PGSS 498 P R GTP SS + G P G Q H K P PG Sbjct: 1240 PPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEF 1299 Query: 499 PLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR 558 P P + + S D +P K+G + + + L G Sbjct: 1300 LAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP 1359 Query: 559 GEAPTRSLHLVSPQVFTSSCVPA---CHQRGFKDPGATRPGVWRWLPEGSAPKP----SP 611 + L + P+ PA C + +D G+ P + R P + +P SP Sbjct: 1360 KDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASP 1419 Query: 612 LHCLESALRGILPV----------------RPLRFACVGGPSPS-PSPGSSSSFSGSEGE 654 S+L LPV L FAC P + PS SF E Sbjct: 1420 PTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEV 1479 Query: 655 DPRPE---PD------LWKPLPQERDRLPSCKPPVP 681 P PD L K P ER +P P +P Sbjct: 1480 SPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLP 1515 Score = 39.7 bits (91), Expect = 0.015 Identities = 104/412 (25%), Positives = 143/412 (34%), Gaps = 94/412 (22%) Query: 109 EPCPLRGLLSCL--PDGPTSQPHLATTPTDSSC-----SSGPTGDGVQGSPLPIKTADKP 161 +P P +G L P P SQ +PT+ +S P D + L K A+K Sbjct: 2523 QPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEK- 2581 Query: 162 WPTRKEGPGALGGEPS--PPTHSPSRRKSHRGQERGTS--EAGISPGNSPL--QGLINCL 215 +EG EP+ P+HS + RG+ RG E I P ++ + G + Sbjct: 2582 ----REGR-RWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRP 2636 Query: 216 KEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEA---VSGDCPLQGL 272 + P S + G A LGPG A +T+ +G+ Q Sbjct: 2637 SPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQ-- 2694 Query: 273 LHCLKELPEAQDRHPSPSGVGNRRLQENP----GAWKRGSGGP------GYLLTPPPHPD 322 DR P + L E P GA RG GP G P Sbjct: 2695 -------KPPGDRMLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPA 2747 Query: 323 LGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSS 382 + S E W ++ P PL P G P+ S P A S +SS Sbjct: 2748 EDSSRAHSRSEEGVWEENTP----------PLGPL------GFPETSSSP---ADSTTSS 2788 Query: 383 PLEALEACLKGIP-----------PNGSSP------SQLPPT------SCSQNPQPGDSR 419 CL+G+P P G +P ++ PP+ S SQ PG Sbjct: 2789 -------CLQGLPDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRL 2841 Query: 420 SQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSS 471 ++K + E+ PVLPL Q +G L P PT S SSS Sbjct: 2842 TRKRNPHVYGKRCEK----PVLPLPTQPSFEEGGDPTLGPARLPTDLSDSSS 2889 Score = 36.2 bits (82), Expect = 0.16 Identities = 142/633 (22%), Positives = 197/633 (31%), Gaps = 182/633 (28%) Query: 411 QNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSS 470 + P P R ++P Q S ++ A R P L R R L PR P + Sbjct: 988 ERPPP---RPRRPRTQAPGSRADPAPRVP-RAAALPEETRSSRRRRLPPRKDPRKRKARG 1043 Query: 471 STDW----------------DLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPV 514 W + DF S Q P +G PG +G KE+ + Sbjct: 1044 GA-WGKELILKIVQQKNRLREYDFASESEEDEQPPPRG--PGFRGRRGRGEKRKEVELT- 1099 Query: 515 LRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVF 574 +GPR EP+ ++ R EA G AP Sbjct: 1100 ------------QGPREDEPQK---PRKAARQEA--------GGDGAPANP--------- 1127 Query: 575 TSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVG 634 ++PG +RPG P S P LE+ R C Sbjct: 1128 -------------EEPGGSRPG-----PGRSPQARGPSRSLETGAAA----REGGPKCAD 1165 Query: 635 GPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP-------CPG 687 PS +P + E+ RP D PQE + + P S P Sbjct: 1166 RPSVAPKDPLQVPTNTETSEETRPSLDF----PQEAKEPETAEESAPDSTEFTEALRSPP 1221 Query: 688 GTPAGSSGGSPGE-DPRRTEPRYCSGLGAGTAQDPCPVSQLEKR-PRVSEASRGLELGHG 745 AG G SPG P + P S GT P P L P S + G+ G Sbjct: 1222 AACAGEMGASPGLLIPEQPPP---SRHDTGT---PKPSGSLANTAPHGSSPTPGVGSLLG 1275 Query: 746 RPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHS 805 P Q P S+ PP P AP P+S+ C KP Sbjct: 1276 GPGGT---------QAPVSHNSKDPPARQPGEFLAPVANPSSTA-----CPKP------- 1314 Query: 806 LGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAH 865 + L+ K+ AG ++ P+G + +GP+ Sbjct: 1315 --SVLSSKISSFGCDPAGFNRD-------------------PLG----VPVAKKGPQ--- 1346 Query: 866 GPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPG 925 PY PK L G C +L +P DAPPA Sbjct: 1347 -------PYSSPHSELFLGPKDLAG----CFLEEL---------HPKPSARDAPPASSSC 1386 Query: 926 LHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAA-----LPLQGASPP--- 977 L C + S P +PP A T ++ PP + ++ LP+ PP Sbjct: 1387 L-CQDGEDAGSLEPQLPRSPPG---TAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYG 1442 Query: 978 --AASADADVPTSGVAP--DGIPERPKEPSSLL 1006 +A+ D+ +P + P +P P PS LL Sbjct: 1443 SLSANRDSGLPFACADPPQKTVPSDPPYPSFLL 1475 Score = 35.8 bits (81), Expect = 0.21 Identities = 201/859 (23%), Positives = 270/859 (31%), Gaps = 174/859 (20%) Query: 140 SSGPTGDGVQGSPLP---IKTADKPWPTRKEGPGALG---GEPSPPTHSPSRRKSHRGQE 193 S G G++GS + + +P P G + G G P P K E Sbjct: 3182 SLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGE 3241 Query: 194 RGTSEAGISPGN-----SPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRAD 248 R A +P N +P L + PGP SPS P P G L +A Sbjct: 3242 RAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPS---PDPWAGGEPLLQAT 3298 Query: 249 LGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEA--QDRH---PSPSGV----GNRRLQE 299 P + S DC HC K P+ RH SP V R+ Sbjct: 3299 ------PVHEACKDPSRDCH-----HCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYP 3347 Query: 300 NPGAWKRGSGGPGYLLTPPP--HPDLGAGGLLSVKMENSWVQSPPGPASCQ---PGRQPL 354 G GG LL P H L A L + M ++ +SC ++ Sbjct: 3348 EHGELLAHLGGAHGLLERPELQHTPLYACELCATVMRI--IKKSFACSSCNYTFAKKEQF 3405 Query: 355 SPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQ 414 RG QP + A ALE L P+ +P ++ P Sbjct: 3406 DRHMNKHLRGGRQPFAFRGVRRPGAPGQKARALEGTL----PSKRRRVAMPGSA----PG 3457 Query: 415 PGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDW 474 PG+ R P S E LP L C PS ++ W Sbjct: 3458 PGEDR-------PPPRGSSPILSEGSLPALLHLCSEVAPS---------------TTKGW 3495 Query: 475 DLDFGSPVGNQGQHPGKGSPPGSSPLQGLE--NCLKEIPVPVLRPAWPCSSAADRGPRRA 532 PV P + P++G E + +E P P L P +P + A RG Sbjct: 3496 PETLERPVD-----------PVTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG---- 3539 Query: 533 EPRNWTADKEGLRAEACESARLGQGRGEA-PTRSLHLVSPQVFTSSCVPACHQRGFKDPG 591 + L + EA P L+ + + +P RG G Sbjct: 3540 --------------DCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEG 3585 Query: 592 ATRPGVW---RWLPEGSAPKPSPLHCLES-ALRGILPVRPLRFACVGGPSPSPSPGSSSS 647 P V+ R P G+ + +P H E L+ V GGP + GS++ Sbjct: 3586 KRAPLVFSGKRRAP-GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATK 3644 Query: 648 FSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLS-PCPGGTPAGSSGGSPGEDPRRTE 706 +G + +DR + P L P GS +PGE R TE Sbjct: 3645 PAGCQSSS--------------KDRSAASTPSKALKFPVHPRKAVGSL--APGELARGTE 3688 Query: 707 PRYCSGLGAGTAQ-DPCPVSQLEKRPRVSEASRGLELGHG---RPRVAAKTHERLLPQGP 762 +G+ T + P P SQ PR G + G G +P E Sbjct: 3689 ----NGMKPATPKAKPGPSSQGSGSPRP-----GTKTGGGSQPQPASGQLQSETATTPAK 3739 Query: 763 PELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALA 822 P PS SP PE P A S + P G+ Q SLG EK + Sbjct: 3740 PSFPSRSPAPERLPARAQ----AKSCTKGPREAGE--QGPHGSLGP--KEKGESSTKRKK 3791 Query: 823 GLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTR 882 G A + V GR P P PR PR P R LP + K ++ Sbjct: 3792 GQVPGPARSES-VGSFGRAPSAPDKP---------PRTPRKQATPS-RVLP-TKPKPNSQ 3839 Query: 883 PKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCH 942 KP+ + G Q R + P P PP + H Sbjct: 3840 NKPRPPPSEQRKAEPGHTQRKD----RLGKAFPQGRPLLRPP-----------KRGTAVH 3884 Query: 943 AAPPAHPLLAHTGGHQSPL 961 A PA P T QS L Sbjct: 3885 GAEPAEPHTHRTAEAQSDL 3903 >gi|95147555 microtubule-associated protein 1A [Homo sapiens] Length = 2803 Score = 57.8 bits (138), Expect = 5e-08 Identities = 184/756 (24%), Positives = 251/756 (33%), Gaps = 143/756 (18%) Query: 97 GERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLAT----TPTDSSCSSGPTGDGVQGSP 152 G+R P A P P L+ + + PT+ LA P D P G P Sbjct: 1807 GQRV-PSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPA-PGPP 1864 Query: 153 LPIKTADKP----WPTRK---------EGPGALGGEPSPPTHSPSRRKSHRGQERGTSEA 199 P + P W T + EG L G P P R+ +E G +EA Sbjct: 1865 TPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEA 1924 Query: 200 GISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRAD---------LG 250 +S + K P +T P P P AD LG Sbjct: 1925 PDKSSHS--SKVPEASKSHATTEPE--QTEPEQREPTPYPDERSFQYADIYEQMMLTGLG 1980 Query: 251 PGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSP-----SGVGNRRLQENPGAWK 305 P P A +GD P CL A R+ S S + + LQ + + Sbjct: 1981 PACPTREPPLGA-AGDWP-----PCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFS 2034 Query: 306 RGS-GGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSP-----PGPA------SCQPGRQP 353 + GP T PP P+ G S+ ++P P P SC P R+ Sbjct: 2035 YAALAGP----TVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRS 2090 Query: 354 LSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGI--PPNGSSPSQLPPTSCSQ 411 SP +G + W S S S LE KG P + S PP Sbjct: 2091 PSPKESGRSH------WDD-----STSDSELE------KGAREQPEKEAQSPSPP----- 2128 Query: 412 NPQPGDSRSQKPELQPHRSHSEEATREPVLP-LGLQSCVRDGPSRPLAPRGTPTSFSSSS 470 +P P S + PE + H S ++ P P L + S AP P+ S Sbjct: 2129 HPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRS 2188 Query: 471 STDWDLDFGSPVGNQGQHPGKGSPPGS--------SPLQGLENCLKEIPVP--------- 513 + L F G++ G P + + L++ L ++P P Sbjct: 2189 APCGSLAFS---GDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLS 2245 Query: 514 -VLRPAWPCSSAADRGPRRAEPRNWTADK--EGLRAEACESARLGQGRGEAPTRSLHLVS 570 + RPA P S + A++ L A ES L G E SL ++ Sbjct: 2246 NLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGM-EPAAHSLWDLT 2304 Query: 571 PQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVR-PLR 629 P S PA P + PG G P L C E+A P + P Sbjct: 2305 P---LSPAPPASLDLALA-PAPSLPG-----DMGDGILPCHLECSEAATEKPSPFQVPSE 2355 Query: 630 FACVGGPSPS----PSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPC 685 GP+ + P P + + + P E W P+ +R S +P LSP Sbjct: 2356 DCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAW---PEGAER--SSRPDTLLSPE 2410 Query: 686 PGGTPAGSSGGSP---------GEDPRRTEPRYCSG-LGAGTAQDPCPVSQLEKRPRVSE 735 PAG SGG P G TEPR G L P P S ++ R +E Sbjct: 2411 QPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPS-IDDRDLSTE 2469 Query: 736 ASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPP 771 R + G GR RV GP + E+PP Sbjct: 2470 EVRLVGRG-GRRRVGGPG----TTGGPCPVTDETPP 2500 Score = 38.1 bits (87), Expect = 0.043 Identities = 110/469 (23%), Positives = 155/469 (33%), Gaps = 90/469 (19%) Query: 550 ESARLGQGRGEAPTRSLHLVSPQVFTSSCVP-ACHQRGFKDPGATRPGVWRWLPEGSAPK 608 E R +GR EAP +S H SS VP A +P T P E P Sbjct: 1913 EGEREEEGRAEAPDKSSH--------SSKVPEASKSHATTEPEQTEP-------EQREPT 1957 Query: 609 PSPLHCL--------ESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEP 660 P P + L G+ P P R +G P S+ + G + E Sbjct: 1958 PYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPP--CLSTKEAAAGRNTSAEK 2015 Query: 661 DLWKPLPQE--RDRLPSCK------PPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSG 712 +L P+ + + P+ P VP P PG P+ +P P R P G Sbjct: 2016 ELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPG--PSMEPSLTPPAVPPRA-PILSKG 2072 Query: 713 LGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGP---PELPSES 769 + S + P E+ GR T + L +G PE ++S Sbjct: 2073 PSPPLNGNILSCSPDRRSPSPKES--------GRSHWDDSTSDSELEKGAREQPEKEAQS 2124 Query: 770 PPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVA 829 P P P P +P + P + H PL L LD A+A + + A Sbjct: 2125 PSPPHPIPMGSPTLWP----ETEAHVSPPLDSHL----GPARPSLDFPASAFGFSSLQPA 2176 Query: 830 TMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKP---- 885 + P P S ++ R A GP PTR + Sbjct: 2177 PPQLP------SPAEPRSAPCGSLAFSGDRALALAPGP------------PTRTRHDEYL 2218 Query: 886 KILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSS-----TPS 940 ++ + L S A LP A PA G ++ ++SS +PS Sbjct: 2219 EVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPS 2278 Query: 941 CHAA-------PPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASAD 982 AA P AH+ +PL P PA+L L A P+ D Sbjct: 2279 LEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGD 2327 >gi|192807323 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform A [Homo sapiens] Length = 1679 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|192807320 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform F [Homo sapiens] Length = 1613 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|192807318 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform E [Homo sapiens] Length = 1614 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|192807316 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform D [Homo sapiens] Length = 1616 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|192807314 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform C [Homo sapiens] Length = 1617 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|192807312 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|21071056 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 57.4 bits (137), Expect = 7e-08 Identities = 98/380 (25%), Positives = 126/380 (33%), Gaps = 74/380 (19%) Query: 77 GEVKGAMDSPE-SESRGASLDGERASPEAAAAREPCPLRGLLSCLPDG-PTSQPHLATTP 134 G GAM P S G++ SP +A P P +G P G P H P Sbjct: 21 GPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-----PGGYPQDNMHQMHKP 75 Query: 135 TDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSP-PTHSPSRRKSHRGQE 193 +S G + D P K R G +G PSP HS G E Sbjct: 76 MESMHEKGMSDD-------PRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSE 128 Query: 194 RGTSEAGIS-----------PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTS 242 +S S PG +PL G + G ++ +P L L Sbjct: 129 HASSPVPASGPSSGPQMSSGPGGAPLDGA-----DPQALGQQNRGPTPFNQNQLHQLRAQ 183 Query: 243 RLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPG 302 + L G P AV G P+ G+ + LP PS S G PG Sbjct: 184 IMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPP-----PSVSATG-------PG 231 Query: 303 AWKRGSGGPGYLLTPP----PHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSA 358 GPG PP PH G GG PPGP+ PG Sbjct: 232 PGPGPGPGPGPGPAPPNYSRPH---GMGGPN---------MPPPGPSGVPPGMP------ 273 Query: 359 TGDTRGVPQPSW--GPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSC----SQN 412 G G P W GP A AA+ +S+P + + G P +P +PP + Q Sbjct: 274 -GQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRP--SPAPPAVPPAASPVMPPQT 330 Query: 413 PQPGDSRSQKPELQPHRSHS 432 PG P + H+ S Sbjct: 331 QSPGQPAQPAPMVPLHQKQS 350 Score = 54.7 bits (130), Expect = 4e-07 Identities = 109/489 (22%), Positives = 154/489 (31%), Gaps = 128/489 (26%) Query: 391 LKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVR 450 L G P G SP P P PG S + S + P+ G + Sbjct: 8 LGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMM-GPSPGPPSAGHPIPTQGPGGYPQ 66 Query: 451 DGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPG---------SSPLQ 501 D + P + S ++ G + G H G G PP SPL Sbjct: 67 DNMHQMHKPMESMHEKGMSDDPRYNQMKGMGM-RSGGHAGMGPPPSPMDQHSQGYPSPLG 125 Query: 502 GLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLG-QGRGE 560 G E+ +P +S GP+ ++ G + + LG Q RG Sbjct: 126 GSEHASSPVP----------ASGPSSGPQ------MSSGPGGAPLDGADPQALGQQNRGP 169 Query: 561 AP--TRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESA 618 P LH + Q+ + G P + +G P P Sbjct: 170 TPFNQNQLHQLRAQIMAYKMLAR---------GQPLPDHLQMAVQGKRPMP--------G 212 Query: 619 LRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKP 678 ++ +P P GP P P PG P P P P P R Sbjct: 213 MQQQMPTLPPPSVSATGPGPGPGPG------------PGPGPG---PAPPNYSRPHGMGG 257 Query: 679 PVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASR 738 P P P G P G G PG P+ P P + P + A+ Sbjct: 258 PNMPPPGPSGVPPGMPGQPPGGPPK-----------------PWP-----EGPMANAAA- 294 Query: 739 GLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQP------- 791 T ++L+P P PS +PP P AA PV+P + P Sbjct: 295 -----------PTSTPQKLIPPQPTGRPSPAPP---AVPPAASPVMPPQTQSPGQPAQPA 340 Query: 792 ---PCH--------CGKP--------LQQELHSLGAALA---EKLDRLATALAGLAQEVA 829 P H KP LQ+ + L A +A ++L+ L +LAG + A Sbjct: 341 PMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKA 400 Query: 830 TMRTQVNRL 838 T+ + RL Sbjct: 401 TIELKALRL 409 Score = 47.8 bits (112), Expect = 5e-05 Identities = 95/420 (22%), Positives = 138/420 (32%), Gaps = 82/420 (19%) Query: 341 PPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSS 400 PP + +PG P + G G PS GP +A + P + IP G Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLG---PSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG-- 60 Query: 401 PSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAP- 459 P P + Q +P +S +K S++ + +G++S G P +P Sbjct: 61 PGGYPQDNMHQMHKPMESMHEK-------GMSDDPRYNQMKGMGMRSGGHAGMGPPPSPM 113 Query: 460 ----RGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVL 515 +G P+ S + P P S PG +PL G + Sbjct: 114 DQHSQGYPSPLGGSEHASSPV----PASGPSSGPQMSSGPGGAPLDGADP---------- 159 Query: 516 RPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGR-----------GEAPTR 564 +RGP P N + LRA+ L +G+ G+ P Sbjct: 160 ----QALGQQNRGPT---PFNQNQLHQ-LRAQIMAYKMLARGQPLPDHLQMAVQGKRPMP 211 Query: 565 SLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILP 624 + P + S AT PG G P P P G P Sbjct: 212 GMQQQMPTLPPPSV------------SATGPGPG----PGPGPGPGP---------GPAP 246 Query: 625 VRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSP 684 R +GGP+ P PG S G G+ P P W P P+ P + P Sbjct: 247 PNYSRPHGMGGPN-MPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305 Query: 685 CPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQL-EKRPRVS--EASRGLE 741 P G P S P P + G P P+ L +K+ R++ + RGL+ Sbjct: 306 QPTGRP---SPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362 Score = 47.0 bits (110), Expect = 9e-05 Identities = 96/368 (26%), Positives = 128/368 (34%), Gaps = 95/368 (25%) Query: 602 PEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPD 661 P G P+P P S G P L GPSP PSPGS+ S G P P P Sbjct: 7 PLGGTPRPGP-----SPGPGPSPGAML------GPSPGPSPGSAHSMMG-----PSPGP- 49 Query: 662 LWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGG------SPGEDPRRTEPRY--CSGL 713 PS P+P PGG P + S E +PRY G+ Sbjct: 50 ------------PSAGHPIPTQG-PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGM 96 Query: 714 G------AGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLP-QGPPELP 766 G AG P P+ Q + G+ P ++ +P GP P Sbjct: 97 GMRSGGHAGMGPPPSPMDQHSQ-------------GYPSPLGGSEHASSPVPASGPSSGP 143 Query: 767 SESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAAL-AEKL--------DRL 817 S P P + A P + P Q +LH L A + A K+ D L Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFN---QNQLHQLRAQIMAYKMLARGQPLPDHL 200 Query: 818 ATA------LAGLAQEVATMRT-QVNRLGRRP-----QGPGPMGQASWMWTLPRG----- 860 A + G+ Q++ T+ V+ G P GPGP G A ++ P G Sbjct: 201 QMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGP-GPAPPNYSRPHGMGGPN 259 Query: 861 --PRWAHG--PGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPP 916 P G PG +P GP +P P+ + + + + R P PP Sbjct: 260 MPPPGPSGVPPG---MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPP 316 Query: 917 DAPPAEPP 924 PPA P Sbjct: 317 AVPPAASP 324 Score = 32.0 bits (71), Expect = 3.1 Identities = 39/163 (23%), Positives = 52/163 (31%), Gaps = 40/163 (24%) Query: 879 GPTRPKPKILRGQGESCRAGDLQGLSRGTARRAR---PLPPDA----PPAEPPGLHCSSS 931 G RP P G G G S G+A P PP A P P G + Sbjct: 10 GTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNM 69 Query: 932 QQLLSSTPSCHA-------------------------APPAHPLLAHTGGHQSPL----- 961 Q+ S H PP P+ H+ G+ SPL Sbjct: 70 HQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPLGGSEH 129 Query: 962 -PPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPS 1003 VPA+ P G P +S P G P + ++ + P+ Sbjct: 130 ASSPVPASGPSSG--PQMSSGPGGAPLDGADPQALGQQNRGPT 170 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 56.2 bits (134), Expect = 2e-07 Identities = 195/784 (24%), Positives = 250/784 (31%), Gaps = 136/784 (17%) Query: 80 KGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSC 139 KGA P + L G R P A RGL+ +P A + +S Sbjct: 309 KGAAGLP-GVAGAPGLPGPRGIPGPVGAAGATGARGLVG--------EPGPAGSKGESGN 359 Query: 140 SSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEA 199 P G QG P P K P + G G P PP S RG A Sbjct: 360 KGEPGSAGPQGPPGPSGEEGKRGPNGEAGSA---GPPGPPGLRGS--PGSRGLPGADGRA 414 Query: 200 GIS--PGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWA 257 G+ PG+ G V GP P P L +G L PGSP Sbjct: 415 GVMGPPGSRGASGPAG------VRGPNGDAGRPGE-PGL--MGPRGL------PGSPG-N 458 Query: 258 VKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGP-GYLLT 316 + G L G+ D P P G R + PG G GP G Sbjct: 459 IGPAGKEGPVGLPGI-----------DGRPGPIGPAGARGE--PG--NIGFPGPKGPTGD 503 Query: 317 PPPHPDLGAGGLLSVKME-----NSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWG 371 P + D G GL + N+ Q PPGP Q G+ P +G+P PS G Sbjct: 504 PGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS-G 562 Query: 372 PEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSH 431 P + L E L G P G + PP G S+ P P Sbjct: 563 PAGEVGKPGERGLHG-EFGLPG--PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDG 619 Query: 432 SEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSP-----VGNQG 486 ++ EP G+ V G + P P G P ++ + G P +GN G Sbjct: 620 NK---GEP----GVVGAV--GTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG 670 Query: 487 QHPGKGSP-----PGSSPLQGLENCLKEIPVPVLRPAWPCSSAADR------GPRRAEPR 535 + +G+P PG + G + PA P S +R GP Sbjct: 671 RDGARGAPGAVGAPGPAGATGDRG--EAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGP 728 Query: 536 NWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATR- 594 A + G + E G+ PT + P PA + PG T Sbjct: 729 AGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGF 788 Query: 595 PG-VWRWLPEG----SAPKPSPLHCLESALRG-------------ILPVRPLRFACVGGP 636 PG R P G S P P + LRG + V P FA GP Sbjct: 789 PGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGP 848 Query: 637 S-------PSPSPGSSS--------SFSGSEGED--PRPEPDLWKPLPQERDRLPSCKPP 679 S P +PG GS GE P + +P P P + P Sbjct: 849 SGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGP 908 Query: 680 VPLSPCPG--GTP--AGSSG-----GSPGEDPR---RTEPRYCSGLG-AGTAQDPCPVSQ 726 PG G P AG G G PG D + + E Y +G G A P P Sbjct: 909 PGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGP 968 Query: 727 LEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPA 786 + P +RG E G P A P GP + + P P P + Sbjct: 969 V--GPAGKHGNRG-ETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGH 1025 Query: 787 SSLQ 790 + LQ Sbjct: 1026 NGLQ 1029 Score = 43.9 bits (102), Expect = 8e-04 Identities = 174/715 (24%), Positives = 227/715 (31%), Gaps = 129/715 (18%) Query: 121 PDGPTSQPHL----ATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEP 176 P GP P L A GP G+ G P A P P +GP GEP Sbjct: 64 PPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEP 123 Query: 177 SPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPL 236 + +R + + G PG +G++ GP+ P P L Sbjct: 124 GQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV---------GPQGARGFPG-TPGL 173 Query: 237 PSL----GTSRLTRADLGPGSP-----PWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHP 287 P G + L PG+P P A G +G LP + R Sbjct: 174 PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG-------LPGERGRVG 226 Query: 288 SPSGVGNRRLQENPG----AWKRGSGG-PGYLLTPPPHPDLGAGGLLSVKMENSWVQSPP 342 +P G R + G A GS G PG+ P P ++GA G N+ P Sbjct: 227 APGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG-------NAGPAGPA 279 Query: 343 GPAS-------CQPGRQPLSPSATGDT-----RGVPQPSWGPEAQAASASSSPLEALEAC 390 GP P P +P A G T G+P + P P+ A A Sbjct: 280 GPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGAT 339 Query: 391 ----LKGIP----PNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLP 442 L G P G S ++ P S PG S E + E + P P Sbjct: 340 GARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS----GEEGKRGPNGEAGSAGPPGP 395 Query: 443 LGLQSCV-------RDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSP- 494 GL+ DG + + P G+ + + + D G P G G +G P Sbjct: 396 PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRP-GEPGLMGPRGLPG 454 Query: 495 -PGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRR----AEPRNWTADKEGLRAEAC 549 PG+ G E + +P RP P A RG P+ T D G + Sbjct: 455 SPGNIGPAGKEGPV-GLPGIDGRPG-PIGPAGARGEPGNIGFPGPKGPTGD-PGKNGDKG 511 Query: 550 ESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAP-- 607 + G P + P P Q G + G P ++ LP S P Sbjct: 512 HAGLAGARGAPGPDGNNGAQGPP------GPQGVQGGKGEQGPPGPPGFQGLPGPSGPAG 565 Query: 608 ---KPSP--LHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDL 662 KP LH E L G R R G P S + G + GS G P PD Sbjct: 566 EVGKPGERGLHG-EFGLPGPAGPRGER----GPPGESGAAGPTGPI-GSRGPSGPPGPDG 619 Query: 663 WKPLPQERDRLPSCKPPVPLSPCPG-----GTPAGSSG----------GSPGEDPRRTEP 707 K P + + P P S PG G P G G+PG D R P Sbjct: 620 NKGEPGVVGAVGTAGPSGP-SGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAP 678 Query: 708 RYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGP 762 G P P R EA G PR + + P GP Sbjct: 679 --------GAVGAPGPAGATGDR---GEAGAAGPAGPAGPRGSPGERGEVGPAGP 722 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.133 0.425 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,139,325 Number of Sequences: 37866 Number of extensions: 4712538 Number of successful extensions: 37440 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 228 Number of HSP's successfully gapped in prelim test: 1681 Number of HSP's that attempted gapping in prelim test: 22035 Number of HSP's gapped (non-prelim): 12785 length of query: 1030 length of database: 18,247,518 effective HSP length: 112 effective length of query: 918 effective length of database: 14,006,526 effective search space: 12857990868 effective search space used: 12857990868 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.