Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116235456
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116235456 ring finger protein 214 [Homo sapiens]
(703 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116235456 ring finger protein 214 [Homo sapiens] 1392 0.0
gi|116235451 ring finger protein 214 [Homo sapiens] 1392 0.0
gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] 122 9e-28
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 102 9e-22
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens] 102 9e-22
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 66 1e-10
gi|55770834 centromere protein F [Homo sapiens] 62 2e-09
gi|41281808 harmonin isoform b3 [Homo sapiens] 58 3e-08
gi|146134388 YLP motif containing 1 [Homo sapiens] 58 3e-08
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 56 1e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 2e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 2e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 2e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 55 2e-07
gi|157168329 formin 1 [Homo sapiens] 55 3e-07
gi|45439370 TAO kinase 1 [Homo sapiens] 54 4e-07
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 54 4e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 54 4e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 54 6e-07
gi|71061468 centromere protein E [Homo sapiens] 54 6e-07
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 54 6e-07
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 53 8e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 53 8e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 53 1e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 53 1e-06
gi|148746195 trichohyalin [Homo sapiens] 53 1e-06
gi|221219024 pleckstrin homology-like domain, family B, member 1... 52 1e-06
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 52 1e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 52 1e-06
gi|203096856 kinesin family member 7 [Homo sapiens] 52 1e-06
>gi|116235456 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 1392 bits (3603), Expect = 0.0
Identities = 703/703 (100%), Positives = 703/703 (100%)
Query: 1 MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKE 60
MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKE
Sbjct: 1 MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKE 60
Query: 61 NNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEG 120
NNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEG
Sbjct: 61 NNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEG 120
Query: 121 DTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG 180
DTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG
Sbjct: 121 DTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG 180
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY
Sbjct: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
Query: 241 QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF 300
QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF
Sbjct: 241 QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF 300
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK
Sbjct: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
Query: 361 ELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ 420
ELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ
Sbjct: 361 ELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ 420
Query: 421 LVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSAD 480
LVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSAD
Sbjct: 421 LVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSAD 480
Query: 481 PRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGV 540
PRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGV
Sbjct: 481 PRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGV 540
Query: 541 KASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLV 600
KASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLV
Sbjct: 541 KASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLV 600
Query: 601 AARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLM 660
AARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLM
Sbjct: 601 AARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLM 660
Query: 661 CQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK 703
CQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK
Sbjct: 661 CQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK 703
>gi|116235451 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 1392 bits (3603), Expect = 0.0
Identities = 703/703 (100%), Positives = 703/703 (100%)
Query: 1 MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKE 60
MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKE
Sbjct: 1 MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKE 60
Query: 61 NNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEG 120
NNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEG
Sbjct: 61 NNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEG 120
Query: 121 DTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG 180
DTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG
Sbjct: 121 DTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG 180
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY
Sbjct: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
Query: 241 QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF 300
QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF
Sbjct: 241 QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF 300
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK
Sbjct: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
Query: 361 ELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ 420
ELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ
Sbjct: 361 ELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ 420
Query: 421 LVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSAD 480
LVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSAD
Sbjct: 421 LVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSAD 480
Query: 481 PRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGV 540
PRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGV
Sbjct: 481 PRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGV 540
Query: 541 KASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLV 600
KASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLV
Sbjct: 541 KASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLV 600
Query: 601 AARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLM 660
AARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLM
Sbjct: 601 AARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLM 660
Query: 661 CQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK 703
CQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK
Sbjct: 661 CQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK 703
>gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]
Length = 1208
Score = 122 bits (307), Expect = 9e-28
Identities = 143/615 (23%), Positives = 260/615 (42%), Gaps = 87/615 (14%)
Query: 110 KDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSL 169
KD S E SL++ L V + TK +++ E++ P +E R
Sbjct: 635 KDGTSIPSESSTESLKD-LQEVKSKQRKKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQ- 692
Query: 170 DFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKM 229
AN R+ +DD D + ++ A++ F + D D + + K+
Sbjct: 693 --------ANPHSVSRLIKDDASD-----VQEDSAMEDKFYSLDELHILDMIEQGSAGKV 739
Query: 230 MTERTLLKERYQEVLDKQRQVEN---QLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKR 286
T+ E +E L +QRQ+ Q + +QL+ +N +I K + +
Sbjct: 740 TTD---YGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQENQMQIKKKDKIIASLN 796
Query: 287 EETK---KKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIME 343
++ K+ K +++ K+ ++K E+L K R WEME L++ +
Sbjct: 797 QQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMK--RSQWEMEKHNLESTMKTYVSKLNA 854
Query: 344 ETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYL----KSTPPTLETVRSKQEWET 399
ET RA AE+ L+ R++ +L LE+ EKE L + S +L+ + W
Sbjct: 855 ETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWNA 914
Query: 400 RLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSL 459
+ VR +R Q+N I V+ G LS+LP + LPPPP + ++Q F P +
Sbjct: 915 IVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPV---QLPPPPPSPEILMQQFLGRPLV 971
Query: 460 APRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLG-SLV 518
+ F +T+P MP+ P +S QP +PL G+ +L
Sbjct: 972 --KESFFRPILTVPQ-MPAVCP---------GVVSATGQPRAPL-------MTGIAWALP 1012
Query: 519 SPHGPHMPPAASIPPPPGLGGVKASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNIL 578
+P G +PP+A + P + E+I ++L T FPQ + ++T+ L
Sbjct: 1013 APVGDAVPPSAGLRSDPS---------------IMNWERITDRLKTAFPQQTRKELTDFL 1057
Query: 579 QQIKTA-RTTMAGLTMEELIQLVAARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFL 637
+++K A +++ LT +E++ + ++ + ++ + + + + + +P S P
Sbjct: 1058 RKLKDAYGKSLSELTFDEIVCKI-SQFIDPKKSQSQGKSVSNVNCV--SPSHSPSQPDAA 1114
Query: 638 PSAQVSYPGRSSHAPATC-------------KLCLMCQKLVQPSELHPMACTHVLHKECI 684
+ ++ +S PAT + C++C + + P L + C H H +CI
Sbjct: 1115 QPPKPAWRPLTSQGPATWEGASNPDEEEEEEEPCVICHENLSPENLSVLPCAHKFHAQCI 1174
Query: 685 KFWAQTNTNDTCPFC 699
+ W TCP C
Sbjct: 1175 RPWLM--QQGTCPTC 1187
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 102 bits (255), Expect = 9e-22
Identities = 120/556 (21%), Positives = 224/556 (40%), Gaps = 78/556 (14%)
Query: 201 QNIAVQTDFKTADSEVNTD-----QDIEKNLDKMMTERTLLKERYQEV-----------L 244
Q +A+Q + EVNT+ ++ + + ++ E +L+++ QEV L
Sbjct: 1462 QMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGL 1521
Query: 245 DKQRQVENQLQVQLKQLQ----------QRREEEMKNHQEILKAIQDVTIKREETKKKIE 294
++ R +E +L+ L++ + Q E E+K Q+ K IQ+ ++ KK+
Sbjct: 1522 EETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVS 1581
Query: 295 KEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQD--GEINRNIMEETERAWKAE 352
+ + QK + E E ++ + +++K ++ + + E +RA AE
Sbjct: 1582 NASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAE 1641
Query: 353 ILSLESRKELLVLKLEEAEKEAELHLTYL---KSTPPTLETVRSK-QEWETRLNGVRIMK 408
+ LE+ KE V KL+ E +AE L L P + S + WE L+ V
Sbjct: 1642 VSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEI 1701
Query: 409 KNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIG 468
+ + QF I+ ++NG++LS L ++ L P T + + S + S
Sbjct: 1702 EKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSAS 1761
Query: 469 QVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPA 528
VT DP + + S PS+ LPG PG GP
Sbjct: 1762 DVTGNHAALHRDP-----SVFSAGDSPGEAPSALLPGP----PPGQPEATQLTGPKRAGQ 1812
Query: 529 ASI-----------PPPPGLGGVKASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNI 577
A++ P PPG A P I+E L FP N ++
Sbjct: 1813 AALSERSPVADRKQPVPPG------RAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGF 1866
Query: 578 LQQIKTA-RTTMAGLTMEELIQLVAARLAEHER-------------VAASTQPLGRIRAL 623
++++++ + +++GL+++E++Q V + + ++ +S P+ R
Sbjct: 1867 IKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQG 1926
Query: 624 FPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLMCQKLVQPSELHPMACTHVLHKEC 683
P+ + S P P R + ++C++ C ++ + + + C H HK C
Sbjct: 1927 SPSVVVAPS-PKTKGQKAEDVPVRIALGASSCEI---CHEVFKSKNVRVLKCGHKYHKGC 1982
Query: 684 IKFWAQTNTNDTCPFC 699
K W + + CP C
Sbjct: 1983 FKQWLKGQS--ACPAC 1996
>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 102 bits (255), Expect = 9e-22
Identities = 120/556 (21%), Positives = 224/556 (40%), Gaps = 78/556 (14%)
Query: 201 QNIAVQTDFKTADSEVNTD-----QDIEKNLDKMMTERTLLKERYQEV-----------L 244
Q +A+Q + EVNT+ ++ + + ++ E +L+++ QEV L
Sbjct: 1462 QMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGL 1521
Query: 245 DKQRQVENQLQVQLKQLQ----------QRREEEMKNHQEILKAIQDVTIKREETKKKIE 294
++ R +E +L+ L++ + Q E E+K Q+ K IQ+ ++ KK+
Sbjct: 1522 EETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVS 1581
Query: 295 KEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQD--GEINRNIMEETERAWKAE 352
+ + QK + E E ++ + +++K ++ + + E +RA AE
Sbjct: 1582 NASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAE 1641
Query: 353 ILSLESRKELLVLKLEEAEKEAELHLTYL---KSTPPTLETVRSK-QEWETRLNGVRIMK 408
+ LE+ KE V KL+ E +AE L L P + S + WE L+ V
Sbjct: 1642 VSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEI 1701
Query: 409 KNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIG 468
+ + QF I+ ++NG++LS L ++ L P T + + S + S
Sbjct: 1702 EKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSAS 1761
Query: 469 QVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPA 528
VT DP + + S PS+ LPG PG GP
Sbjct: 1762 DVTGNHAALHRDP-----SVFSAGDSPGEAPSALLPGP----PPGQPEATQLTGPKRAGQ 1812
Query: 529 ASI-----------PPPPGLGGVKASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNI 577
A++ P PPG A P I+E L FP N ++
Sbjct: 1813 AALSERSPVADRKQPVPPG------RAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGF 1866
Query: 578 LQQIKTA-RTTMAGLTMEELIQLVAARLAEHER-------------VAASTQPLGRIRAL 623
++++++ + +++GL+++E++Q V + + ++ +S P+ R
Sbjct: 1867 IKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQG 1926
Query: 624 FPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLMCQKLVQPSELHPMACTHVLHKEC 683
P+ + S P P R + ++C++ C ++ + + + C H HK C
Sbjct: 1927 SPSVVVAPS-PKTKGQKAEDVPVRIALGASSCEI---CHEVFKSKNVRVLKCGHKYHKGC 1982
Query: 684 IKFWAQTNTNDTCPFC 699
K W + + CP C
Sbjct: 1983 FKQWLKGQS--ACPAC 1996
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.9 bits (159), Expect = 1e-10
Identities = 80/338 (23%), Positives = 143/338 (42%), Gaps = 58/338 (17%)
Query: 242 EVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKR--------------- 286
E+ ++R+ ++++ +++ ++RREEE + +E KA +KR
Sbjct: 443 EIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502
Query: 287 --EETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEE 344
E +++ E+E+++ L+KEQ+ + E E+ ++ R++ E EL++ + + E+ + +E
Sbjct: 503 EIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE 562
Query: 345 TERAWKAEILSLESRKELLVLKLEEAEKEAELHL------TYLKSTPPTLETVRSKQEWE 398
E+ L + KE + K++E EKE EL ++ P LE + KQE E
Sbjct: 563 KEKE-----LERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESE 617
Query: 399 TRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQI----PTPTLPPPPSETDFMLQVFQ 454
N +++ + N ++ + P + P P P+ + FQ
Sbjct: 618 NSCN---------KEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQ 668
Query: 455 PSPSLAPRMPFSIGQV------------TMPMVMPSADPRSLSFPILNPALSQPSQPSSP 502
SL PR Q+ +P +PS S P + L QP QP
Sbjct: 669 --KSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQ 726
Query: 503 LPGSHGRNSPGL--GSLVSPHGPHMPPAASIPP-PPGL 537
S G + L S + P PA IPP PG+
Sbjct: 727 HLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGM 764
Score = 53.9 bits (128), Expect = 5e-07
Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 64/305 (20%)
Query: 213 DSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNH 272
+ E +++ EK L+K E+ KER + D++RQ E + +++ K+ +++RE E +
Sbjct: 506 EREREKEREREKELEKEQ-EQEREKEREK---DRERQQEKEKELE-KEQEKQREMEKERK 560
Query: 273 QEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELD---R 329
QE K +E +++ EKEK+ KEQ+ + E+EK EK ++ E +
Sbjct: 561 QE----------KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM 610
Query: 330 LKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYL-------- 381
++ Q+ E + N +E E + + + ++ V+ E E ++ L
Sbjct: 611 VEKQESENSCN--KEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQ 668
Query: 382 KSTPPTLETVR---SKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIP-TP 437
KS PP + + +Q+W+ Q + G ++P P +
Sbjct: 669 KSLPPRFQRQQEQMKQQQWQ---------------------QQQQQGVLPQTVPSQPSSS 707
Query: 438 TLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLS------FPILNP 491
T+PPPP + Q QP P M F + M M DPR +S P ++P
Sbjct: 708 TVPPPPHRP--LYQPMQPHPQHLASMGFDPRWLMMQSYM---DPRMMSGRPAMDIPPIHP 762
Query: 492 ALSQP 496
+ P
Sbjct: 763 GMIPP 767
Score = 40.0 bits (92), Expect = 0.007
Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 18/128 (14%)
Query: 435 PTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPS----ADPRSL------ 484
P P P P + P+ + A + S + P P + P S+
Sbjct: 1800 PVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASA 1859
Query: 485 SFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASA 544
S PIL AL+ S P+ P P + +SP + +P P P AS+P P ASA
Sbjct: 1860 SIPILASALASTSAPT-PAPAA---SSPAAPVITAPTIPASAPTASVPLAP----ASASA 1911
Query: 545 ETPRPQPV 552
P P PV
Sbjct: 1912 PAPAPTPV 1919
Score = 31.2 bits (69), Expect = 3.4
Identities = 58/246 (23%), Positives = 89/246 (36%), Gaps = 34/246 (13%)
Query: 436 TPTLPPPPSETDFM-LQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALS 494
T LPP ++ +Q Q S S+ P + +P ++ P S S P+
Sbjct: 1722 TSKLPPRFAKKQATGIQQAQSSASVPP-----LASAPLPPSTSASVPASTSAPLPATLTP 1776
Query: 495 QPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAETPRPQPVDK 554
P+ S+P+P S +P L S +P +P P L V ASA P
Sbjct: 1777 VPASTSAPVPAS--TLAPVLASTSAP----------VPASP-LAPVSASASVSASVPA-- 1821
Query: 555 LEKILEKLLTRFPQCNKAQMTNILQQIKT--ARTTMAGLTMEELIQLVAARLAEHERVAA 612
+ + + T IL + T + T +A ++ L +A+ A AA
Sbjct: 1822 -STSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAA 1880
Query: 613 STQPLGRIRALFPAPLAQIST-PMFLPSAQVSYPGRSSHAPATCKLCLMCQKLVQPSELH 671
S+ AP+ T P P+A V S+ APA + P+
Sbjct: 1881 SSP---------AAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQ 1931
Query: 672 PMACTH 677
A TH
Sbjct: 1932 TQAQTH 1937
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 61.6 bits (148), Expect = 2e-09
Identities = 109/485 (22%), Positives = 195/485 (40%), Gaps = 82/485 (16%)
Query: 7 AGVVANAPSPPESSSLCASKSDEGLP---------DGLSTKDSAQKQKNSPLLSVSSQTI 57
A ++ S P S C ++D+ D L +QKQ NS L + +
Sbjct: 798 ANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELV 857
Query: 58 TKENNRNVHLEHSEQNPGSSAGDTS----------AAHQVVLGENLIATALCLSGSGSQS 107
+ +L +EQ S +TS +AHQ V+ E L A L +
Sbjct: 858 QIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSA----LENKEKEL 913
Query: 108 DLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSI-------- 159
L + + L++S H + SLK QL S S EK +SI
Sbjct: 914 QLLNDKVETEQAEIQELKKSNHLLEDSLKE----LQLLSETLSLEKKEMSSIISLNKREI 969
Query: 160 ---------LKEGNRDTSLDFRPVVSPANGVEGVRVDQDDD--QDSSSLKLSQNIAVQTD 208
LKE N + + ++ + +++ + S K + I +Q
Sbjct: 970 EELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRC 1029
Query: 209 FKTADSEVNTDQDI----EKN--LDKMMTERTLLKER---------------YQEVLDKQ 247
+T ++ + Q EKN L+ ++ E T L E +QE L K
Sbjct: 1030 EETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKL 1089
Query: 248 RQVENQ---LQVQLKQLQQRREEEMKNHQEILKA----IQDVTIKREETKKKIEKEKKEF 300
E + L ++L+ +QQ EM ++Q K+ ++ + +E + K++KE +
Sbjct: 1090 AFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDL 1149
Query: 301 LQKEQDL------KAEIEKL-CEKGRREVWEMELDRLK-NQDGEINRNIMEETERAWKAE 352
LQ+ + L K E + L E R V E E +R + N +++ + E + ++ A+
Sbjct: 1150 LQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQ 1209
Query: 353 ILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVR 412
++ LE+ LKL+E+EKE E L++ LET + ++G++ + +
Sbjct: 1210 LVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAE 1269
Query: 413 DQFNS 417
+++ S
Sbjct: 1270 EKYIS 1274
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/157 (23%), Positives = 77/157 (49%), Gaps = 13/157 (8%)
Query: 228 KMMTERTLLKERYQEVLD-KQRQVENQ---LQVQLKQLQQRREEEMKNHQEILKAIQDVT 283
K + ER QE K++ + +Q L+++ QL Q +E N+ + ++ +
Sbjct: 2448 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLI 2507
Query: 284 IKREETKKKIEKEKKEFLQKE---QDLKAEIEKLCE-KGRREVWEMELDRLKNQDGEINR 339
+ E+ K+K+EK+ +E + + QD + + KL + +G ++W+ + L+N E+ +
Sbjct: 2508 QEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQ 2567
Query: 340 NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAEL 376
I + +++ SL+ E+L + E E EL
Sbjct: 2568 KI-----QVLQSKNASLQDTLEVLQSSYKNLENELEL 2599
Score = 41.2 bits (95), Expect = 0.003
Identities = 61/288 (21%), Positives = 123/288 (42%), Gaps = 68/288 (23%)
Query: 151 EEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRV---DQDDDQDSSSLKLSQNIAV-- 205
E+K + S LK +D +VS + VEG +Q+ + + +++L Q I V
Sbjct: 2518 EKKDEEISRLKNQIQDQE----QLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 2573
Query: 206 -------------QTDFKTADSEVN-TDQD----IEKNLDKMMTERTLLKERYQEVLDKQ 247
Q+ +K ++E+ T D +EK ++KM + T L+ E+ K
Sbjct: 2574 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VNKMTAKETELQREMHEMAQKT 2632
Query: 248 RQVENQLQVQLKQLQQRRE---EEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKE 304
+++ +L + +L + EE+K+ ++ LK ++T++ E KK ++ K+ ++KE
Sbjct: 2633 AELQEELSGEKNRLAGELQLLLEEIKSSKDQLK---ELTLENSELKKSLDCMHKDQVEKE 2689
Query: 305 QDLKAEI---------------------------------EKLCEKGR-REVWEMELDRL 330
++ EI EKL K ++E+D L
Sbjct: 2690 GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLL 2749
Query: 331 KNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHL 378
K+ E+N ++ T+ + + +++ K + LK E + ++ L
Sbjct: 2750 KSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKL 2797
Score = 39.7 bits (91), Expect = 0.010
Identities = 51/212 (24%), Positives = 94/212 (44%), Gaps = 31/212 (14%)
Query: 192 QDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVE 251
Q++ S + S ++ K E++ Q + LD+ E +K R + L + + +
Sbjct: 376 QNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQ---ECIQMKARLTQELQQAKNMH 432
Query: 252 NQLQVQLKQLQQRREEEMKNHQEILK-------AIQDVTIKREETKKKIEKEKKE--FLQ 302
N LQ +L +L +++ N +E + A Q IK E ++ +E+ KKE L+
Sbjct: 433 NVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLK 492
Query: 303 KEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKEL 362
+ KA REV +E + LKN +N++ + + E+ + + +E
Sbjct: 493 SHSEQKA----------REVCHLEAE-LKNIKQCLNQS------QNFAEEMKAKNTSQET 535
Query: 363 LVLKLEEA--EKEAELHLTYLKSTPPTLETVR 392
++ L+E ++E L L LK LE R
Sbjct: 536 MLRDLQEKINQQENSLTLEKLKLAVADLEKQR 567
Score = 37.7 bits (86), Expect = 0.037
Identities = 50/241 (20%), Positives = 98/241 (40%), Gaps = 21/241 (8%)
Query: 142 KQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQ 201
++ + C E++ Q S +KE S+ E ++ + + + S K +
Sbjct: 454 EEFKQKLCRAEQAFQASQIKENELRRSM------------EEMKKENNLLKSHSEQKARE 501
Query: 202 NIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQ-LKQ 260
++ + K +N Q+ + + T + + QE +++Q EN L ++ LK
Sbjct: 502 VCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ---ENSLTLEKLKL 558
Query: 261 LQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLC-EKGR 319
E++ Q++LK + + + K EKE K L + K E E+L EK
Sbjct: 559 AVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTL 618
Query: 320 REVWEMELDRLKNQDGEINRNI---MEETERAWKA-EILSLESRKELLVLKLEEAEKEAE 375
W+ E ++L Q N+ + E K +I S E + + L+++ E
Sbjct: 619 FSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVE 678
Query: 376 L 376
+
Sbjct: 679 I 679
Score = 34.7 bits (78), Expect = 0.31
Identities = 58/306 (18%), Positives = 125/306 (40%), Gaps = 44/306 (14%)
Query: 151 EEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFK 210
+E +P S L+ G RD + F S + ++ ++ + ++ + + +Q K
Sbjct: 250 QEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKIN---ELELRLQGHEK 306
Query: 211 TADSEVNTDQDIEKNLDKMMTE----------------RTLLK-----ERYQEVLDKQRQ 249
+VN Q+++ L+K E RT + +Y + K ++
Sbjct: 307 EMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKK 366
Query: 250 VENQLQVQLKQ-------LQQRREEEMKNHQEIL----KAIQDVTIKREETKKKIEKEKK 298
+ L Q + L+Q+ +E+ K QE L ++ Q + + + K ++ +E +
Sbjct: 367 LTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQ 426
Query: 299 EFLQKEQDLKAEIEKLCE-----KGRREVWEMELDRLKN--QDGEINRNIMEETERAWKA 351
+ L+AE++KL + E ++ +L R + Q +I N + + K
Sbjct: 427 QAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKK 486
Query: 352 EILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNV 411
E L+S E ++ E E + L + E +++K + + +R +++ +
Sbjct: 487 ENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETM--LRDLQEKI 544
Query: 412 RDQFNS 417
Q NS
Sbjct: 545 NQQENS 550
Score = 32.0 bits (71), Expect = 2.0
Identities = 75/374 (20%), Positives = 152/374 (40%), Gaps = 46/374 (12%)
Query: 18 ESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKENNRNVH-LEHSEQNPGS 76
+ SS C S+ P+ L D Q++ L + + + EN R +H +E ++ S
Sbjct: 1740 QGSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVES 1799
Query: 77 SAGDTSAA-HQVVLGENLIATAL--CLSGSGSQSDLKDVASTAGEEGD---TSLRESLHP 130
+ ++ L E + T + C+ +LK S E+ + +E L
Sbjct: 1800 LLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQR 1859
Query: 131 VTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDD 190
V S + A ++ E+ + + + ++ LD N + +R ++
Sbjct: 1860 VETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVE------NELSRIRSEKAS 1913
Query: 191 DQDSSSLKLSQNIAVQTDFKTADSEVNTDQDI----EKNLDKMMTERTLLKERYQEVLDK 246
+ + + VQT+ + + Q + E+ L + +ER L+ + K
Sbjct: 1914 IEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKK 1973
Query: 247 QRQVENQLQVQLKQLQQRREEEMKNHQ-EILKAIQDVTIKREETKKKIE------KEKKE 299
++ QL + + + +E+++HQ E L IQ + E K+K E + E
Sbjct: 1974 TTALD-----QLSEKMKEKTQELESHQSECLHCIQ---VAEAEVKEKTELLQTLSSDVSE 2025
Query: 300 FLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESR 359
L+ + L+ +++ L EK + + + L+NQ ++N+ + E+L ES
Sbjct: 2026 LLKDKTHLQEKLQSL-EKDSQAL-SLTKCELENQIAQLNK----------EKELLVKES- 2072
Query: 360 KELLVLKLEEAEKE 373
E L +L E++ E
Sbjct: 2073 -ESLQARLSESDYE 2085
Score = 31.6 bits (70), Expect = 2.6
Identities = 56/282 (19%), Positives = 126/282 (44%), Gaps = 38/282 (13%)
Query: 123 SLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVE 182
+L+ + +T+SL+ G + R SE+++ + KE R + L+ +++ + E
Sbjct: 2368 TLKAKIEGMTQSLR-GLELDVVTIR--SEKENLTNELQKEQERISELE---IIN--SSFE 2419
Query: 183 GVRVDQDDDQDSSSLKLSQNIAV---QTDFKTADSEV---NTDQDI----EKNLDKMMTE 232
+ Q+ +Q+ +K + A+ QT K + V + DQ+ E+NL +
Sbjct: 2420 NIL--QEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEC 2477
Query: 233 RTLLKERYQEVLDKQRQ----VENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREE 288
L K + + LD+ + +++ + +++++ +++ K +EI + + + +
Sbjct: 2478 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2537
Query: 289 TKKKIEKEKKEFLQKEQ---------DLKAEIEKLCEKGR--REVWEMELDRLKNQDGEI 337
K + E + L KEQ +L+ +I+ L K ++ E+ KN + E+
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEL 2597
Query: 338 NRNIMEE---TERAWKAEILSLESRKELLVLKLEEAEKEAEL 376
M++ E+ K E ++E+ + + AE + EL
Sbjct: 2598 ELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEEL 2639
Score = 30.8 bits (68), Expect = 4.5
Identities = 31/149 (20%), Positives = 73/149 (48%), Gaps = 7/149 (4%)
Query: 238 ERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK 297
+ Y+E L + + + ++++ L+ +EE + + + ++++ + + K + + K
Sbjct: 2726 QTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLK 2785
Query: 298 KEFLQKEQDLKAEIEKLCE--KGRREVWEMELDRLK-NQDGEINRNIMEETERAWKAEIL 354
KE + + +K I K C+ + +E+ + EL +L+ Q+ + +M+ EI
Sbjct: 2786 KENERAQGKMKLLI-KSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIK 2844
Query: 355 SLESRKELLVLKLEEAEKEAELHLTYLKS 383
L KE L K +EA++ + + + L S
Sbjct: 2845 EL---KETLEEKTKEADEYLDKYCSLLIS 2870
Score = 30.4 bits (67), Expect = 5.9
Identities = 48/216 (22%), Positives = 97/216 (44%), Gaps = 27/216 (12%)
Query: 203 IAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQ 262
+ ++ + SE N + LD M + T L + +++ +K +++E+ Q +
Sbjct: 1947 VCLEEELSVVTSERN---QLRGELDTMSKKTTALDQLSEKMKEKTQELESH-QSECLHCI 2002
Query: 263 QRREEEMKNHQEILKAI-QDVT------IKREETKKKIEKEKKEFLQKEQDLKAEIEKLC 315
Q E E+K E+L+ + DV+ +E + +EK+ + + +L+ +I +L
Sbjct: 2003 QVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Query: 316 EKGRREVWEME--LDRLKNQDGE-------INRNIMEETERAWK-----AEILSLESRKE 361
++ V E E RL D E + ++E+ E A + E+ L E
Sbjct: 2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIE 2122
Query: 362 LLVLKLEEAEKEAELHLT-YLKSTPPTLETVRSKQE 396
L +++E EK+ +LH+ LK ++++ K E
Sbjct: 2123 KLRVRIEADEKK-QLHIAEKLKERERENDSLKDKVE 2157
>gi|41281808 harmonin isoform b3 [Homo sapiens]
Length = 899
Score = 58.2 bits (139), Expect = 3e-08
Identities = 100/441 (22%), Positives = 166/441 (37%), Gaps = 94/441 (21%)
Query: 166 DTSLDFRPVVSPANGVEGVRVDQDDD----QDSSSLKLSQNIAVQTDFKTADSEVNTD-Q 220
+ L+ + NGV+ +D + + S SL +S A + D E + +
Sbjct: 249 EVGLEIGDQIVEVNGVDFSNLDHKEAVNVLKSSRSLTISIVAAAGRELFMTDRERLAEAR 308
Query: 221 DIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQ 280
E +++ ++ L E ++L +Q+++E Q + K++ Q+ EE + ++ K ++
Sbjct: 309 QRELQRQELLMQKRLAMES-NKILQEQQEMERQRR---KEIAQKAAEENERYR---KEME 361
Query: 281 DVTIKREETKKKIEKE--KKEFLQKEQDLKAEIEKL-CEKGRREVWEMELD------RLK 331
+ + E+ KK+ E++ KE L + + AE+ + K + W D R K
Sbjct: 362 QIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPKSFGWFYRYDGKFPTIRKK 421
Query: 332 NQD------GEI-----NRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTY 380
+D G + N+ +E ++ +K + LE K+L + +L + E E
Sbjct: 422 GKDKKKAKYGSLQDLRKNKKELEFEQKLYKEKEEMLEKEKQLKINRLAQEVSETERE--- 478
Query: 381 LKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLP 440
LE Q W RL R+ + + D + + ++ T P
Sbjct: 479 ------DLEESEKIQYWVERLCQTRLEQISSAD---------------NEISEMTTGPPP 517
Query: 441 PPPSETDFMLQVFQPSPSLAPRMPFSIG--------------QVTMPMVMPSADPRSLSF 486
PPPS SP P F+ G P PSA P
Sbjct: 518 PPPSV----------SPLAPPLRRFAGGLHLHTTDLDDIPLDMFYYPPKTPSALPVMPHP 567
Query: 487 PILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAET 546
P NP P+ P PL G +S SP PP IPPPP S T
Sbjct: 568 PPSNPPHKVPAPPVLPLSGHVSASS-------SPWVQRTPPPIPIPPPP-------SVPT 613
Query: 547 PRPQPVDKLEKILEKLLTRFP 567
P L LE+ L+ P
Sbjct: 614 QDLTPTRPLPSALEEALSNHP 634
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 58.2 bits (139), Expect = 3e-08
Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 13/182 (7%)
Query: 368 EEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRN--- 424
+E E+E +L L S P + +++W+T ++ + ++++ NS Q ++N
Sbjct: 453 QEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNS-FQNMKNQYM 511
Query: 425 GAKLSSLPQIPTPTLPPP-PSETDFMLQVFQPSPSLAPRMPFSIGQVTM-PMVMPSADPR 482
G P +P +PPP P+ +L P P + P +P ++ M P VMP + P
Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571
Query: 483 SLSFPILNPALSQPSQPSSPLPGSHGRNS-------PGLGSLVSPHGPHMPPAASIPPPP 535
S+ P + P+LS P P S P L S P +PP +S PPP
Sbjct: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP 631
Query: 536 GL 537
G+
Sbjct: 632 GI 633
Score = 34.3 bits (77), Expect = 0.41
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 7/115 (6%)
Query: 442 PPSETDFMLQVFQPSPSLAPR--MPFSIGQVTMPMVMPSADPRSLSFPILNPAL-----S 494
PP L+ SP + P MP S + P PS P + S P L PA S
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194
Query: 495 QPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAETPRP 549
PSQ S+ +S S +S ++P + + P P G K+ P P
Sbjct: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPP 249
Score = 33.5 bits (75), Expect = 0.69
Identities = 38/142 (26%), Positives = 51/142 (35%), Gaps = 37/142 (26%)
Query: 442 PPSETDFMLQVFQPSPSLAP-----RMPFSIGQVTMPMVMPSADPRSLSFPILNPALS-Q 495
PP E+ LQ P + P R P +G+ +V PSA P S P+ P +
Sbjct: 1490 PPQES--RLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP 1547
Query: 496 PSQPSSPLP---------------------GSHG----RNSPGLGSLVSPHGPHMPPAAS 530
P P PLP +G + GL S +P A
Sbjct: 1548 PPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPV 1607
Query: 531 IPPPPGLGGVKASAETPRPQPV 552
+PPPP V +S P P P+
Sbjct: 1608 LPPPP----VHSSIPPPGPVPM 1625
Score = 31.6 bits (70), Expect = 2.6
Identities = 30/102 (29%), Positives = 37/102 (36%), Gaps = 14/102 (13%)
Query: 434 IPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPAL 493
+P P LPPPP +QP P P MP G + L P
Sbjct: 81 LPPPPLPPPPVMPGGGYGDWQPPP---PPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137
Query: 494 SQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPP 535
P + SP SP + P G +MPP+ S PPP
Sbjct: 138 LVPMELESP------PESPPV-----PPGSYMPPSQSYMPPP 168
Score = 30.8 bits (68), Expect = 4.5
Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 434 IPTPTLPP---PPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILN 490
+P P PP PP+ + L QPSPS +P + P S+ S + +
Sbjct: 165 MPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLA----PTPSYSSSSSSSQSYLSH 220
Query: 491 PALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPA--ASIPPPPGLGGVKASA---- 544
PS +SP S G + L++P P PP ++ P G K +
Sbjct: 221 SQSYLPSSQASPSRPSQGHSK---SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQ 277
Query: 545 -ETPRPQP 551
P P P
Sbjct: 278 QAAPEPDP 285
Score = 30.0 bits (66), Expect = 7.6
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 20/105 (19%)
Query: 432 PQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNP 491
P P P LPPPP V +P S + + + + + + D + L+ +
Sbjct: 1548 PPPPPPPLPPPP-------PVIKPQTSAVEQERWD--EDSFYGLWDTNDEQGLNSEFKSE 1598
Query: 492 ALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGP---HMPPAASIPP 533
+ PS P P P H S + P GP MPP + PP
Sbjct: 1599 TAAIPSAPVLPPPPVH--------SSIPPPGPVPMGMPPMSKPPP 1635
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 56.2 bits (134), Expect = 1e-07
Identities = 72/332 (21%), Positives = 148/332 (44%), Gaps = 43/332 (12%)
Query: 127 SLHPVTRSLKAGCHTKQLASR--NCSEEKSPQTSILKEGNRDTSLDFRPVVSPANG-VEG 183
SL LK Q+++ N + + +T+ L DT+ R + ++ ++
Sbjct: 535 SLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQ 594
Query: 184 VRVDQDDDQDSSSLKLSQNIAVQTDF-------------KTADSEVNTD---------QD 221
+ + D QD + L + + ++ +F +T SE+ D +D
Sbjct: 595 LESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEED 654
Query: 222 IEKN---LDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKA 278
++ L K+ E+ L+ER+ ++ ++ +E + QLK +QQ E+E H+
Sbjct: 655 LKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKAR 714
Query: 279 IQD---VTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG 335
+ D + EE K + KE ++ L +E+ LK ++E L + + ++ D LK
Sbjct: 715 LADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCD-LKQSQQ 773
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVR-SK 394
+IN + ++ ++L+ + R L LK+E+ ++ L LK + T++ S+
Sbjct: 774 KINELLKQK-------DVLNEDVRN--LTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSE 824
Query: 395 QEWETRLNGVRIMKKNVRDQFNSHIQLVRNGA 426
++ + N + MK N+ Q N+ ++ R A
Sbjct: 825 KQLKQENNHLMEMKMNLEKQ-NAELRKERQDA 855
Score = 47.0 bits (110), Expect = 6e-05
Identities = 59/238 (24%), Positives = 103/238 (43%), Gaps = 26/238 (10%)
Query: 189 DDDQDSSSLKLSQNIA----VQTDFKTADSEVNTDQDIEKNL---DKMMTERTLLKERYQ 241
++D + +LK+ Q Q D K +VNT + EK L + + E + E+
Sbjct: 786 NEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQN 845
Query: 242 EVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFL 301
L K+RQ Q+K+LQ + E E ++++ +EE ++K K KE
Sbjct: 846 AELRKERQ---DADGQMKELQDQLEAEQYFSTLYKTQVREL---KEECEEK-TKLGKELQ 898
Query: 302 QKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAE--ILSLESR 359
QK+Q+L+ E + L ++E+ K ++ R+I EE + E + LE +
Sbjct: 899 QKKQELQDERDSLAA-------QLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIK 951
Query: 360 KELLVLKLEEAEKE---AELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQ 414
+ + K E EK+ A L T T K+E +L V+ ++D+
Sbjct: 952 EMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDE 1009
Score = 42.0 bits (97), Expect = 0.002
Identities = 55/257 (21%), Positives = 120/257 (46%), Gaps = 36/257 (14%)
Query: 210 KTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEM 269
K +S + K ++K + E LK++ + +L + + + L LKQ QQ+ E +
Sbjct: 720 KIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELL 779
Query: 270 KNHQEILKAIQDVTIK-REETKKK--IEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEME 326
K + + ++++T+K +ET+K+ + + K Q+ LK EK ++ + EM+
Sbjct: 780 KQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMS-EKQLKQENNHLMEMK 838
Query: 327 LDRLKNQDGEINRNIME------------ETER----AWKAEILSLE---SRKELLVLKL 367
++ L+ Q+ E+ + + E E+ +K ++ L+ K L +L
Sbjct: 839 MN-LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKEL 897
Query: 368 EEAEKE---------AELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKK-NVRDQFNS 417
++ ++E A+L +T K+ L +++++ + L +IMK+ +++
Sbjct: 898 QQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQY-SDLEKEKIMKELEIKEMMAR 956
Query: 418 HIQ-LVRNGAKLSSLPQ 433
H Q L A ++SL +
Sbjct: 957 HKQELTEKDATIASLEE 973
Score = 35.0 bits (79), Expect = 0.24
Identities = 33/174 (18%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Query: 243 VLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQ 302
+ ++ + ++Q +L L++ EM+ +E+ + + V + E+T K++E+E
Sbjct: 434 IQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKS 493
Query: 303 KEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESR--- 359
E L+ ++E+ EK + E R + + + RN +E + K ++ L+ R
Sbjct: 494 VESALR-QLER--EKALLQHKNAEYQRKADHEADKKRN-LENDVNSLKDQLEDLKKRNQN 549
Query: 360 KELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRD 413
++ K+ + +++ + L++ T +R Q ++ ++ ++ N RD
Sbjct: 550 SQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSK--QIQQLESNNRD 601
Score = 30.8 bits (68), Expect = 4.5
Identities = 41/231 (17%), Positives = 101/231 (43%), Gaps = 30/231 (12%)
Query: 105 SQSDLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSE--EKSPQTSILKE 162
+++D + +A + EE + L + + K++ +R+ E EK + L+E
Sbjct: 920 TKADSEQLARSIAEEQYSDLEKE------KIMKELEIKEMMARHKQELTEKDATIASLEE 973
Query: 163 GNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDI 222
NR + D V + AN E + D Q+ S + D E++
Sbjct: 974 TNRTLTSD---VANLANEKEELNNKLKDVQEQLS-------------RLKDEEISAAAIK 1017
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDV 282
+ +++TERTL + ++ + + E + ++++ +E K H E+ + +
Sbjct: 1018 AQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKL 1077
Query: 283 TIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQ 333
T + + +K++ E + + +E ++ E++ + + ++++L++Q
Sbjct: 1078 TQQMIKYQKEL-NEMQAQIAEESQIRIELQMTLDSK-----DSDIEQLRSQ 1122
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/219 (23%), Positives = 112/219 (51%), Gaps = 13/219 (5%)
Query: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Q E L ++ + + L E + +L +Q Q E +L + ++++ R + + +EIL +
Sbjct: 869 QKAENELKELEQKHSQLTEE-KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 280 QDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL----DRLKNQDG 335
+ + E+ ++++ E+K+ Q+ DL+ ++E+ E+ R+ ++E ++K +
Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIKKLED 985
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLET---VR 392
EI +M++ E LE R L L E E++A+ +LT LK+ ++ + VR
Sbjct: 986 EI--LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKNKHESMISELEVR 1042
Query: 393 SKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSL 431
K+E ++R ++ +K D + H Q+ A+++ L
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Score = 49.7 bits (117), Expect = 9e-06
Identities = 63/289 (21%), Positives = 129/289 (44%), Gaps = 51/289 (17%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+EG D +D DS + ++N A + + ++E LD T++ L +R
Sbjct: 1116 LEGHISDLQEDLDSE--RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1173
Query: 241 QEVLDKQRQVENQL---QVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE- 296
QEV ++ ++ + + Q+++++Q+ + ++ E L+ + ++ K+ +EKE
Sbjct: 1174 QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1233
Query: 297 -------------KKEFLQKEQDLKAEIEKL---CEKGRREVWEM--ELDRLKNQDGEIN 338
K+E K++ L+A++++L C G R E+ ++ +L+N+ +
Sbjct: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 339 RNIMEETERAWK---------------AEILSLESRKELLV-LKLEEAEKEAELHLTYLK 382
+ E +A K E+L E+R++L V KL + E+E L
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 383 STPPTLETVRSKQEWETRLNGVRIM----KKNVRDQFNSHIQLVRNGAK 427
E + +KQ E ++ + I KK ++D F S ++ + G K
Sbjct: 1354 ------EEMEAKQNLERHISTLNIQLSDSKKKLQD-FASTVEALEEGKK 1395
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/250 (21%), Positives = 119/250 (47%), Gaps = 34/250 (13%)
Query: 187 DQDDDQDSSSLKLS-QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVL- 244
+Q ++++++ KL + + + K + E+ D L K ER LL+ER ++
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK---ERKLLEERISDLTT 1013
Query: 245 ----------------DKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREE 288
+K + ++L+V+LK+ ++ R+E K +++ D + +
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
Query: 289 TKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERA 348
+ +I + K + +KE++L+A + +L ++ ++ L +++ +G I+ ++E +
Sbjct: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRELEGHISD--LQEDLDS 1129
Query: 349 WKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMK 408
+A E +K L +LE + E E L + T + +R+K+E E V ++K
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQE-----VTVLK 1180
Query: 409 KNVRDQFNSH 418
K + ++ SH
Sbjct: 1181 KALDEETRSH 1190
Score = 43.5 bits (101), Expect = 7e-04
Identities = 43/165 (26%), Positives = 77/165 (46%), Gaps = 8/165 (4%)
Query: 198 KLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQ 257
+LS +A T+ TA + Q +E+ ++ R+ L E V K + L+ +
Sbjct: 1768 QLSNELA--TERSTAQKNESARQQLERQNKEL---RSKLHEMEGAVKSKFKSTIAALEAK 1822
Query: 258 LKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQ-KEQDLKAEIEKLCE 316
+ QL+++ E+E + Q K+++ K +E ++E E+K Q KEQ K
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 317 KGRREVWEMELDRLKNQDGEINRNIMEETE--RAWKAEILSLESR 359
K + E E E R+ ++ R + E TE A E+ +L+S+
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/428 (19%), Positives = 180/428 (42%), Gaps = 64/428 (14%)
Query: 40 SAQKQKNSPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALC 99
S+Q Q LL ++ + + LE + + A Q + E I+T L
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL--ERHIST-LN 1370
Query: 100 LSGSGSQSDLKDVAST--AGEEGDTSLRESLHPVTRSL--KAGCHTKQLASRNCSEEKSP 155
+ S S+ L+D AST A EEG ++ + +T+ KA + K ++N +++
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 156 QTSILKEGNRD--TSLD-----FRPVVSPANGVEGVRVDQDD-------DQDSSSLKLSQ 201
+ + R ++L+ F +++ + D+ D ++++ +L L++
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 202 NIAVQTDFKT----------ADSE--VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQ 249
+ + K A+ E V++ D+ KN+ ++ + L+ + +E+ + +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 250 VENQLQVQ------------------LKQLQQRREEEMKNHQEILKAIQDVTIKREETKK 291
+E++LQ + LQ R E+ + +++ + + + + E+ +K
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Query: 292 K-----IEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETE 346
+ K+K E K+ +L+A+ KGR E + +L +L+ Q + R + E
Sbjct: 1611 QRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIK-QLRKLQAQMKDFQREL--EDA 1664
Query: 347 RAWKAEILSL--ESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGV 404
RA + EI + E+ K+ L+ + + + +L LE +E + L+G
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
Query: 405 RIMKKNVR 412
++ R
Sbjct: 1725 NALQDEKR 1732
Score = 39.3 bits (90), Expect = 0.013
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 49/252 (19%)
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQ------VENQLQVQLKQLQQRREEEMKNHQEIL 276
E+N +K + L E E+ D+++Q + +L+ LK L+ + + +K +E +
Sbjct: 1585 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 1644
Query: 277 KAI--------------QDVTIKREE---TKKKIEKEKK----EFLQKEQDLKAEIEKLC 315
K + +D R+E T K+ EK+ K + +Q ++DL A
Sbjct: 1645 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA-----A 1699
Query: 316 EKGRREVWEMELDRLKNQ--DGEINRNIMEETERAWKAEILSLE-------SRKELLVLK 366
E+ R++ ++E + L + RN +++ +R +A I LE E + +
Sbjct: 1700 ERARKQA-DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
Query: 367 LEEAEKEAEL---HLTYLKSTPPTLETVRSKQEWETR--LNGVRIMKKNVRDQFNSHIQL 421
+ +A ++AE L +ST E+ R + E + + + + M+ V+ +F S I
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
Query: 422 VRNGAKLSSLPQ 433
+ AK++ L +
Sbjct: 1819 LE--AKIAQLEE 1828
Score = 37.7 bits (86), Expect = 0.037
Identities = 39/224 (17%), Positives = 96/224 (42%), Gaps = 23/224 (10%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+E R +D+ ++ + +++ D ++ + K D E+ L E
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD---LEKEELAEEL 1717
Query: 241 QEVLDKQRQVENQ---LQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK 297
L + ++++ L+ ++ QL++ EEE N + + ++ T + E+ ++ E+
Sbjct: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
Query: 298 KEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLE 357
QK + + ++E+ ++ R ++ EME + +K+ I +LE
Sbjct: 1778 ST-AQKNESARQQLERQNKELRSKLHEME----------------GAVKSKFKSTIAALE 1820
Query: 358 SRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRL 401
++ L ++E+ +E + LK L+ + + E E ++
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
Score = 34.7 bits (78), Expect = 0.31
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 17/134 (12%)
Query: 253 QLQVQLKQLQQ--RREEEMKNHQEILKAIQDVTIKREETKKKIEKEK----------KEF 300
+L ++K L Q R+EEEM+ ++ L+ ++ K E K++E++ +E
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
LQ E +L AE E++ + R + EL+ + + E+ + EE +R + + + +
Sbjct: 896 LQAETELYAEAEEM--RVRLAAKKQELEEILH---EMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 361 ELLVLKLEEAEKEA 374
++L L+ + E+EA
Sbjct: 951 QMLDLEEQLEEEEA 964
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/219 (23%), Positives = 112/219 (51%), Gaps = 13/219 (5%)
Query: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Q E L ++ + + L E + +L +Q Q E +L + ++++ R + + +EIL +
Sbjct: 876 QKAENELKELEQKHSQLTEE-KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 934
Query: 280 QDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL----DRLKNQDG 335
+ + E+ ++++ E+K+ Q+ DL+ ++E+ E+ R+ ++E ++K +
Sbjct: 935 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIKKLED 992
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLET---VR 392
EI +M++ E LE R L L E E++A+ +LT LK+ ++ + VR
Sbjct: 993 EI--LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKNKHESMISELEVR 1049
Query: 393 SKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSL 431
K+E ++R ++ +K D + H Q+ A+++ L
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088
Score = 49.7 bits (117), Expect = 9e-06
Identities = 63/289 (21%), Positives = 129/289 (44%), Gaps = 51/289 (17%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+EG D +D DS + ++N A + + ++E LD T++ L +R
Sbjct: 1123 LEGHISDLQEDLDSE--RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1180
Query: 241 QEVLDKQRQVENQL---QVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE- 296
QEV ++ ++ + + Q+++++Q+ + ++ E L+ + ++ K+ +EKE
Sbjct: 1181 QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1240
Query: 297 -------------KKEFLQKEQDLKAEIEKL---CEKGRREVWEM--ELDRLKNQDGEIN 338
K+E K++ L+A++++L C G R E+ ++ +L+N+ +
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 339 RNIMEETERAWK---------------AEILSLESRKELLV-LKLEEAEKEAELHLTYLK 382
+ E +A K E+L E+R++L V KL + E+E L
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 383 STPPTLETVRSKQEWETRLNGVRIM----KKNVRDQFNSHIQLVRNGAK 427
E + +KQ E ++ + I KK ++D F S ++ + G K
Sbjct: 1361 ------EEMEAKQNLERHISTLNIQLSDSKKKLQD-FASTVEALEEGKK 1402
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/250 (21%), Positives = 119/250 (47%), Gaps = 34/250 (13%)
Query: 187 DQDDDQDSSSLKLS-QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVL- 244
+Q ++++++ KL + + + K + E+ D L K ER LL+ER ++
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK---ERKLLEERISDLTT 1020
Query: 245 ----------------DKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREE 288
+K + ++L+V+LK+ ++ R+E K +++ D + +
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080
Query: 289 TKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERA 348
+ +I + K + +KE++L+A + +L ++ ++ L +++ +G I+ ++E +
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRELEGHISD--LQEDLDS 1136
Query: 349 WKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMK 408
+A E +K L +LE + E E L + T + +R+K+E E V ++K
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQE-----VTVLK 1187
Query: 409 KNVRDQFNSH 418
K + ++ SH
Sbjct: 1188 KALDEETRSH 1197
Score = 43.5 bits (101), Expect = 7e-04
Identities = 43/165 (26%), Positives = 77/165 (46%), Gaps = 8/165 (4%)
Query: 198 KLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQ 257
+LS +A T+ TA + Q +E+ ++ R+ L E V K + L+ +
Sbjct: 1775 QLSNELA--TERSTAQKNESARQQLERQNKEL---RSKLHEMEGAVKSKFKSTIAALEAK 1829
Query: 258 LKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQ-KEQDLKAEIEKLCE 316
+ QL+++ E+E + Q K+++ K +E ++E E+K Q KEQ K
Sbjct: 1830 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 317 KGRREVWEMELDRLKNQDGEINRNIMEETE--RAWKAEILSLESR 359
K + E E E R+ ++ R + E TE A E+ +L+S+
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/428 (19%), Positives = 180/428 (42%), Gaps = 64/428 (14%)
Query: 40 SAQKQKNSPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALC 99
S+Q Q LL ++ + + LE + + A Q + E I+T L
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL--ERHIST-LN 1377
Query: 100 LSGSGSQSDLKDVAST--AGEEGDTSLRESLHPVTRSL--KAGCHTKQLASRNCSEEKSP 155
+ S S+ L+D AST A EEG ++ + +T+ KA + K ++N +++
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 156 QTSILKEGNRD--TSLD-----FRPVVSPANGVEGVRVDQDD-------DQDSSSLKLSQ 201
+ + R ++L+ F +++ + D+ D ++++ +L L++
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 202 NIAVQTDFKT----------ADSE--VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQ 249
+ + K A+ E V++ D+ KN+ ++ + L+ + +E+ + +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 250 VENQLQVQ------------------LKQLQQRREEEMKNHQEILKAIQDVTIKREETKK 291
+E++LQ + LQ R E+ + +++ + + + + E+ +K
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617
Query: 292 K-----IEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETE 346
+ K+K E K+ +L+A+ KGR E + +L +L+ Q + R + E
Sbjct: 1618 QRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIK-QLRKLQAQMKDFQREL--EDA 1671
Query: 347 RAWKAEILSL--ESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGV 404
RA + EI + E+ K+ L+ + + + +L LE +E + L+G
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1731
Query: 405 RIMKKNVR 412
++ R
Sbjct: 1732 NALQDEKR 1739
Score = 39.3 bits (90), Expect = 0.013
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 49/252 (19%)
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQ------VENQLQVQLKQLQQRREEEMKNHQEIL 276
E+N +K + L E E+ D+++Q + +L+ LK L+ + + +K +E +
Sbjct: 1592 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 1651
Query: 277 KAI--------------QDVTIKREE---TKKKIEKEKK----EFLQKEQDLKAEIEKLC 315
K + +D R+E T K+ EK+ K + +Q ++DL A
Sbjct: 1652 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA-----A 1706
Query: 316 EKGRREVWEMELDRLKNQ--DGEINRNIMEETERAWKAEILSLE-------SRKELLVLK 366
E+ R++ ++E + L + RN +++ +R +A I LE E + +
Sbjct: 1707 ERARKQA-DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 367 LEEAEKEAEL---HLTYLKSTPPTLETVRSKQEWETR--LNGVRIMKKNVRDQFNSHIQL 421
+ +A ++AE L +ST E+ R + E + + + + M+ V+ +F S I
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 422 VRNGAKLSSLPQ 433
+ AK++ L +
Sbjct: 1826 LE--AKIAQLEE 1835
Score = 37.7 bits (86), Expect = 0.037
Identities = 39/224 (17%), Positives = 96/224 (42%), Gaps = 23/224 (10%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+E R +D+ ++ + +++ D ++ + K D E+ L E
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD---LEKEELAEEL 1724
Query: 241 QEVLDKQRQVENQ---LQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK 297
L + ++++ L+ ++ QL++ EEE N + + ++ T + E+ ++ E+
Sbjct: 1725 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
Query: 298 KEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLE 357
QK + + ++E+ ++ R ++ EME + +K+ I +LE
Sbjct: 1785 ST-AQKNESARQQLERQNKELRSKLHEME----------------GAVKSKFKSTIAALE 1827
Query: 358 SRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRL 401
++ L ++E+ +E + LK L+ + + E E ++
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871
Score = 34.7 bits (78), Expect = 0.31
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 17/134 (12%)
Query: 253 QLQVQLKQLQQ--RREEEMKNHQEILKAIQDVTIKREETKKKIEKEK----------KEF 300
+L ++K L Q R+EEEM+ ++ L+ ++ K E K++E++ +E
Sbjct: 843 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
LQ E +L AE E++ + R + EL+ + + E+ + EE +R + + + +
Sbjct: 903 LQAETELYAEAEEM--RVRLAAKKQELEEILH---EMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 361 ELLVLKLEEAEKEA 374
++L L+ + E+EA
Sbjct: 958 QMLDLEEQLEEEEA 971
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/219 (23%), Positives = 112/219 (51%), Gaps = 13/219 (5%)
Query: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Q E L ++ + + L E + +L +Q Q E +L + ++++ R + + +EIL +
Sbjct: 876 QKAENELKELEQKHSQLTEE-KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 934
Query: 280 QDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL----DRLKNQDG 335
+ + E+ ++++ E+K+ Q+ DL+ ++E+ E+ R+ ++E ++K +
Sbjct: 935 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIKKLED 992
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLET---VR 392
EI +M++ E LE R L L E E++A+ +LT LK+ ++ + VR
Sbjct: 993 EI--LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKNKHESMISELEVR 1049
Query: 393 SKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSL 431
K+E ++R ++ +K D + H Q+ A+++ L
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088
Score = 49.7 bits (117), Expect = 9e-06
Identities = 63/289 (21%), Positives = 129/289 (44%), Gaps = 51/289 (17%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+EG D +D DS + ++N A + + ++E LD T++ L +R
Sbjct: 1123 LEGHISDLQEDLDSE--RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1180
Query: 241 QEVLDKQRQVENQL---QVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE- 296
QEV ++ ++ + + Q+++++Q+ + ++ E L+ + ++ K+ +EKE
Sbjct: 1181 QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1240
Query: 297 -------------KKEFLQKEQDLKAEIEKL---CEKGRREVWEM--ELDRLKNQDGEIN 338
K+E K++ L+A++++L C G R E+ ++ +L+N+ +
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 339 RNIMEETERAWK---------------AEILSLESRKELLV-LKLEEAEKEAELHLTYLK 382
+ E +A K E+L E+R++L V KL + E+E L
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 383 STPPTLETVRSKQEWETRLNGVRIM----KKNVRDQFNSHIQLVRNGAK 427
E + +KQ E ++ + I KK ++D F S ++ + G K
Sbjct: 1361 ------EEMEAKQNLERHISTLNIQLSDSKKKLQD-FASTVEALEEGKK 1402
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/250 (21%), Positives = 119/250 (47%), Gaps = 34/250 (13%)
Query: 187 DQDDDQDSSSLKLS-QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVL- 244
+Q ++++++ KL + + + K + E+ D L K ER LL+ER ++
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK---ERKLLEERISDLTT 1020
Query: 245 ----------------DKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREE 288
+K + ++L+V+LK+ ++ R+E K +++ D + +
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080
Query: 289 TKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERA 348
+ +I + K + +KE++L+A + +L ++ ++ L +++ +G I+ ++E +
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRELEGHISD--LQEDLDS 1136
Query: 349 WKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMK 408
+A E +K L +LE + E E L + T + +R+K+E E V ++K
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQE-----VTVLK 1187
Query: 409 KNVRDQFNSH 418
K + ++ SH
Sbjct: 1188 KALDEETRSH 1197
Score = 43.5 bits (101), Expect = 7e-04
Identities = 43/165 (26%), Positives = 77/165 (46%), Gaps = 8/165 (4%)
Query: 198 KLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQ 257
+LS +A T+ TA + Q +E+ ++ R+ L E V K + L+ +
Sbjct: 1775 QLSNELA--TERSTAQKNESARQQLERQNKEL---RSKLHEMEGAVKSKFKSTIAALEAK 1829
Query: 258 LKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQ-KEQDLKAEIEKLCE 316
+ QL+++ E+E + Q K+++ K +E ++E E+K Q KEQ K
Sbjct: 1830 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 317 KGRREVWEMELDRLKNQDGEINRNIMEETE--RAWKAEILSLESR 359
K + E E E R+ ++ R + E TE A E+ +L+S+
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Score = 40.4 bits (93), Expect = 0.006
Identities = 51/282 (18%), Positives = 119/282 (42%), Gaps = 22/282 (7%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+E R +D+ ++ + +++ D ++ + K D E+ L E
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD---LEKEELAEEL 1724
Query: 241 QEVLDKQRQVENQ---LQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK 297
L + ++++ L+ ++ QL++ EEE N + + ++ T + E+ ++ E+
Sbjct: 1725 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
Query: 298 KEFLQKEQDLKAEIEKLCEKGRREVWEME---LDRLKNQDGEINRNI------MEETERA 348
QK + + ++E+ ++ R ++ EME + K+ + I +E+ R
Sbjct: 1785 ST-AQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843
Query: 349 WKAEILSLESRKELL---VLKLEEAEKEAELHLTYL-KSTPPTLETVRSKQEWETRLNGV 404
+A SL+ + + L +L++E+ K AE + K + R +E E +
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903
Query: 405 RIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSET 446
++ ++ + + + N A + + + PPP ET
Sbjct: 1904 NANRRKLQRELDEATE--SNEAMGREVNALKSKLRGPPPQET 1943
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/428 (19%), Positives = 180/428 (42%), Gaps = 64/428 (14%)
Query: 40 SAQKQKNSPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALC 99
S+Q Q LL ++ + + LE + + A Q + E I+T L
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL--ERHIST-LN 1377
Query: 100 LSGSGSQSDLKDVAST--AGEEGDTSLRESLHPVTRSL--KAGCHTKQLASRNCSEEKSP 155
+ S S+ L+D AST A EEG ++ + +T+ KA + K ++N +++
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 156 QTSILKEGNRD--TSLD-----FRPVVSPANGVEGVRVDQDD-------DQDSSSLKLSQ 201
+ + R ++L+ F +++ + D+ D ++++ +L L++
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 202 NIAVQTDFKT----------ADSE--VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQ 249
+ + K A+ E V++ D+ KN+ ++ + L+ + +E+ + +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 250 VENQLQVQ------------------LKQLQQRREEEMKNHQEILKAIQDVTIKREETKK 291
+E++LQ + LQ R E+ + +++ + + + + E+ +K
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617
Query: 292 K-----IEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETE 346
+ K+K E K+ +L+A+ KGR E + +L +L+ Q + R + E
Sbjct: 1618 QRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIK-QLRKLQAQMKDFQREL--EDA 1671
Query: 347 RAWKAEILSL--ESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGV 404
RA + EI + E+ K+ L+ + + + +L LE +E + L+G
Sbjct: 1672 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1731
Query: 405 RIMKKNVR 412
++ R
Sbjct: 1732 NALQDEKR 1739
Score = 39.3 bits (90), Expect = 0.013
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 49/252 (19%)
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQ------VENQLQVQLKQLQQRREEEMKNHQEIL 276
E+N +K + L E E+ D+++Q + +L+ LK L+ + + +K +E +
Sbjct: 1592 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 1651
Query: 277 KAI--------------QDVTIKREE---TKKKIEKEKK----EFLQKEQDLKAEIEKLC 315
K + +D R+E T K+ EK+ K + +Q ++DL A
Sbjct: 1652 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA-----A 1706
Query: 316 EKGRREVWEMELDRLKNQ--DGEINRNIMEETERAWKAEILSLE-------SRKELLVLK 366
E+ R++ ++E + L + RN +++ +R +A I LE E + +
Sbjct: 1707 ERARKQA-DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 367 LEEAEKEAEL---HLTYLKSTPPTLETVRSKQEWETR--LNGVRIMKKNVRDQFNSHIQL 421
+ +A ++AE L +ST E+ R + E + + + + M+ V+ +F S I
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 422 VRNGAKLSSLPQ 433
+ AK++ L +
Sbjct: 1826 LE--AKIAQLEE 1835
Score = 34.7 bits (78), Expect = 0.31
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 17/134 (12%)
Query: 253 QLQVQLKQLQQ--RREEEMKNHQEILKAIQDVTIKREETKKKIEKEK----------KEF 300
+L ++K L Q R+EEEM+ ++ L+ ++ K E K++E++ +E
Sbjct: 843 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
LQ E +L AE E++ + R + EL+ + + E+ + EE +R + + + +
Sbjct: 903 LQAETELYAEAEEM--RVRLAAKKQELEEILH---EMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 361 ELLVLKLEEAEKEA 374
++L L+ + E+EA
Sbjct: 958 QMLDLEEQLEEEEA 971
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/219 (23%), Positives = 112/219 (51%), Gaps = 13/219 (5%)
Query: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Q E L ++ + + L E + +L +Q Q E +L + ++++ R + + +EIL +
Sbjct: 869 QKAENELKELEQKHSQLTEE-KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 280 QDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL----DRLKNQDG 335
+ + E+ ++++ E+K+ Q+ DL+ ++E+ E+ R+ ++E ++K +
Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIKKLED 985
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLET---VR 392
EI +M++ E LE R L L E E++A+ +LT LK+ ++ + VR
Sbjct: 986 EI--LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NLTKLKNKHESMISELEVR 1042
Query: 393 SKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSL 431
K+E ++R ++ +K D + H Q+ A+++ L
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Score = 49.7 bits (117), Expect = 9e-06
Identities = 63/289 (21%), Positives = 129/289 (44%), Gaps = 51/289 (17%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+EG D +D DS + ++N A + + ++E LD T++ L +R
Sbjct: 1116 LEGHISDLQEDLDSE--RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1173
Query: 241 QEVLDKQRQVENQL---QVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE- 296
QEV ++ ++ + + Q+++++Q+ + ++ E L+ + ++ K+ +EKE
Sbjct: 1174 QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1233
Query: 297 -------------KKEFLQKEQDLKAEIEKL---CEKGRREVWEM--ELDRLKNQDGEIN 338
K+E K++ L+A++++L C G R E+ ++ +L+N+ +
Sbjct: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 339 RNIMEETERAWK---------------AEILSLESRKELLV-LKLEEAEKEAELHLTYLK 382
+ E +A K E+L E+R++L V KL + E+E L
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 383 STPPTLETVRSKQEWETRLNGVRIM----KKNVRDQFNSHIQLVRNGAK 427
E + +KQ E ++ + I KK ++D F S ++ + G K
Sbjct: 1354 ------EEMEAKQNLERHISTLNIQLSDSKKKLQD-FASTVEALEEGKK 1395
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/250 (21%), Positives = 119/250 (47%), Gaps = 34/250 (13%)
Query: 187 DQDDDQDSSSLKLS-QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVL- 244
+Q ++++++ KL + + + K + E+ D L K ER LL+ER ++
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK---ERKLLEERISDLTT 1013
Query: 245 ----------------DKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREE 288
+K + ++L+V+LK+ ++ R+E K +++ D + +
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
Query: 289 TKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERA 348
+ +I + K + +KE++L+A + +L ++ ++ L +++ +G I+ ++E +
Sbjct: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRELEGHISD--LQEDLDS 1129
Query: 349 WKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMK 408
+A E +K L +LE + E E L + T + +R+K+E E V ++K
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQE-----VTVLK 1180
Query: 409 KNVRDQFNSH 418
K + ++ SH
Sbjct: 1181 KALDEETRSH 1190
Score = 43.5 bits (101), Expect = 7e-04
Identities = 43/165 (26%), Positives = 77/165 (46%), Gaps = 8/165 (4%)
Query: 198 KLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQ 257
+LS +A T+ TA + Q +E+ ++ R+ L E V K + L+ +
Sbjct: 1768 QLSNELA--TERSTAQKNESARQQLERQNKEL---RSKLHEMEGAVKSKFKSTIAALEAK 1822
Query: 258 LKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQ-KEQDLKAEIEKLCE 316
+ QL+++ E+E + Q K+++ K +E ++E E+K Q KEQ K
Sbjct: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 317 KGRREVWEMELDRLKNQDGEINRNIMEETE--RAWKAEILSLESR 359
K + E E E R+ ++ R + E TE A E+ +L+S+
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Score = 40.4 bits (93), Expect = 0.006
Identities = 51/282 (18%), Positives = 119/282 (42%), Gaps = 22/282 (7%)
Query: 181 VEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY 240
+E R +D+ ++ + +++ D ++ + K D E+ L E
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD---LEKEELAEEL 1717
Query: 241 QEVLDKQRQVENQ---LQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK 297
L + ++++ L+ ++ QL++ EEE N + + ++ T + E+ ++ E+
Sbjct: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
Query: 298 KEFLQKEQDLKAEIEKLCEKGRREVWEME---LDRLKNQDGEINRNI------MEETERA 348
QK + + ++E+ ++ R ++ EME + K+ + I +E+ R
Sbjct: 1778 ST-AQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
Query: 349 WKAEILSLESRKELL---VLKLEEAEKEAELHLTYL-KSTPPTLETVRSKQEWETRLNGV 404
+A SL+ + + L +L++E+ K AE + K + R +E E +
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896
Query: 405 RIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSET 446
++ ++ + + + N A + + + PPP ET
Sbjct: 1897 NANRRKLQRELDEATE--SNEAMGREVNALKSKLRGPPPQET 1936
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/428 (19%), Positives = 180/428 (42%), Gaps = 64/428 (14%)
Query: 40 SAQKQKNSPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALC 99
S+Q Q LL ++ + + LE + + A Q + E I+T L
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL--ERHIST-LN 1370
Query: 100 LSGSGSQSDLKDVAST--AGEEGDTSLRESLHPVTRSL--KAGCHTKQLASRNCSEEKSP 155
+ S S+ L+D AST A EEG ++ + +T+ KA + K ++N +++
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 156 QTSILKEGNRD--TSLD-----FRPVVSPANGVEGVRVDQDD-------DQDSSSLKLSQ 201
+ + R ++L+ F +++ + D+ D ++++ +L L++
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 202 NIAVQTDFKT----------ADSE--VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQ 249
+ + K A+ E V++ D+ KN+ ++ + L+ + +E+ + +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 250 VENQLQVQ------------------LKQLQQRREEEMKNHQEILKAIQDVTIKREETKK 291
+E++LQ + LQ R E+ + +++ + + + + E+ +K
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Query: 292 K-----IEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETE 346
+ K+K E K+ +L+A+ KGR E + +L +L+ Q + R + E
Sbjct: 1611 QRALAAAAKKKLEGDLKDLELQAD---SAIKGREEAIK-QLRKLQAQMKDFQREL--EDA 1664
Query: 347 RAWKAEILSL--ESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGV 404
RA + EI + E+ K+ L+ + + + +L LE +E + L+G
Sbjct: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
Query: 405 RIMKKNVR 412
++ R
Sbjct: 1725 NALQDEKR 1732
Score = 39.3 bits (90), Expect = 0.013
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 49/252 (19%)
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQ------VENQLQVQLKQLQQRREEEMKNHQEIL 276
E+N +K + L E E+ D+++Q + +L+ LK L+ + + +K +E +
Sbjct: 1585 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 1644
Query: 277 KAI--------------QDVTIKREE---TKKKIEKEKK----EFLQKEQDLKAEIEKLC 315
K + +D R+E T K+ EK+ K + +Q ++DL A
Sbjct: 1645 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA-----A 1699
Query: 316 EKGRREVWEMELDRLKNQ--DGEINRNIMEETERAWKAEILSLE-------SRKELLVLK 366
E+ R++ ++E + L + RN +++ +R +A I LE E + +
Sbjct: 1700 ERARKQA-DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
Query: 367 LEEAEKEAEL---HLTYLKSTPPTLETVRSKQEWETR--LNGVRIMKKNVRDQFNSHIQL 421
+ +A ++AE L +ST E+ R + E + + + + M+ V+ +F S I
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
Query: 422 VRNGAKLSSLPQ 433
+ AK++ L +
Sbjct: 1819 LE--AKIAQLEE 1828
Score = 34.7 bits (78), Expect = 0.31
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 17/134 (12%)
Query: 253 QLQVQLKQLQQ--RREEEMKNHQEILKAIQDVTIKREETKKKIEKEK----------KEF 300
+L ++K L Q R+EEEM+ ++ L+ ++ K E K++E++ +E
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
LQ E +L AE E++ + R + EL+ + + E+ + EE +R + + + +
Sbjct: 896 LQAETELYAEAEEM--RVRLAAKKQELEEILH---EMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 361 ELLVLKLEEAEKEA 374
++L L+ + E+EA
Sbjct: 951 QMLDLEEQLEEEEA 964
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 54.7 bits (130), Expect = 3e-07
Identities = 69/269 (25%), Positives = 106/269 (39%), Gaps = 33/269 (12%)
Query: 297 KKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSL 356
K+E ++ ++L+A+ E R E M RL+ E N+ E E W+
Sbjct: 507 KREHKEEIENLQAQFELRAFHIRGE-HAMITARLE----ETIENLKHELEHRWRG---GC 558
Query: 357 ESRKELLVLKLEEAEKEAELHL-------TYLKSTPPTLETVRSKQEWETRLNGVRIMK- 408
E RK++ + ++ + ++ T+LK +T RS Q +LN + +
Sbjct: 559 EERKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQL 618
Query: 409 --KNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFS 466
N ++ +Q + A P P PPP L P+P P P S
Sbjct: 619 SPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAP---PMPPVS 675
Query: 467 IGQVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMP 526
G P+ P P L P + A P P PLP S +PG P P
Sbjct: 676 AGP---PLPPPPPPPPPLPPP--SSAGPPPPPPPPPLPNSPAPPNPG-----GPPPAPPP 725
Query: 527 PAASIPPPPGL--GGVKASAETPRPQPVD 553
P + PPPPGL G +S++ PR ++
Sbjct: 726 PGLAPPPPPGLFFGLGSSSSQCPRKPAIE 754
>gi|45439370 TAO kinase 1 [Homo sapiens]
Length = 1001
Score = 54.3 bits (129), Expect = 4e-07
Identities = 89/434 (20%), Positives = 173/434 (39%), Gaps = 58/434 (13%)
Query: 33 DGLSTKDSAQKQKNSPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSAAHQVVLGEN 92
D + D+ Q +K LL + N V + E+ G T + V G N
Sbjct: 299 DAVRELDNLQYRKMKKLLFQEAH-----NGPAVEAQEEEEEQDHGVGRTGTVNSV--GSN 351
Query: 93 LIATALCLSGSGSQSDLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEE 152
++ +S S S + + + ++ + + E H V S + H K N EE
Sbjct: 352 QSIPSMSISASSQSSSVNSLPDVSDDKSELDMMEGDHTVM-SNSSVIHLKP-EEENYREE 409
Query: 153 KSPQT---------SILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKL---- 199
P+T + + + + + + A+ V R Q+ +QDS +
Sbjct: 410 GDPRTRASDPQSPPQVSRHKSHYRNREHFATIRTASLV--TRQMQEHEQDSELREQMSGY 467
Query: 200 --------SQNIAVQTDFKTADSE--VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQ 249
Q + ++ K E + D+D+E + E L +++Q ++K+ +
Sbjct: 468 KRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAK 527
Query: 250 V--------ENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFL 301
V + +Q Q K+ E K ++ K + + + E + +KEK+E+L
Sbjct: 528 VMSNEEKKFQQHIQAQQKKELNSFLESQKREYKLRK--EQLKEELNENQSTPKKEKQEWL 585
Query: 302 QKE----QDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLE 357
K+ Q +AE E + +R+ E+E R K + N+ ++ R E+ +
Sbjct: 586 SKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVR---EELNKRQ 642
Query: 358 SRKEL---LVLKLEEAEKEAEL-HLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRD 413
++K+L ++L+ E+ +E E HL ++ E +R + + E N + K+ R+
Sbjct: 643 TQKDLEHAMLLRQHESMQELEFRHLNTIQKM--RCELIRLQHQTEL-TNQLEYNKRRERE 699
Query: 414 QFNSHIQLVRNGAK 427
H+ VR K
Sbjct: 700 LRRKHVMEVRQQPK 713
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 54.3 bits (129), Expect = 4e-07
Identities = 45/136 (33%), Positives = 72/136 (52%), Gaps = 15/136 (11%)
Query: 222 IEKNLDKMMTERTLLK-ERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQ 280
I K K TE+ L+ +R QE L KQ + L+ REE+ K +E +A +
Sbjct: 321 ITKKFVKGSTEKNKLRLQRDQERLGKQLK-----------LRAEREEKEKLKEEAKRAKE 369
Query: 281 DVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCE---KGRREVWEMELDRLKNQDGEI 337
+ K+EE K+ EKE++E +K++ KAE ++L E K R+E E +L+ + ++ E
Sbjct: 370 EAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429
Query: 338 NRNIMEETERAWKAEI 353
E+ +A KAEI
Sbjct: 430 RLREEEKRIKAEKAEI 445
Score = 39.7 bits (91), Expect = 0.010
Identities = 35/135 (25%), Positives = 66/135 (48%), Gaps = 19/135 (14%)
Query: 184 VRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEV 243
+R+ +D ++ LKL +E + +++ + E KE +E+
Sbjct: 335 LRLQRDQERLGKQLKLR-------------AEREEKEKLKEEAKRAKEEAKKKKEEEKEL 381
Query: 244 LDKQRQVENQLQVQLKQLQQR-REEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQ 302
+K+R+ + + + K +QR +EE K QE L+A + K+EE K+ E+EK+ ++
Sbjct: 382 KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR--IK 439
Query: 303 KEQDLKAEIEKLCEK 317
E KAEI + +K
Sbjct: 440 AE---KAEITRFFQK 451
Score = 31.6 bits (70), Expect = 2.6
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 11/91 (12%)
Query: 287 EETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETE 346
++ K + E+E+KE L++E E K ++ +E+ E E + +D E E
Sbjct: 346 KQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKD---------EKE 396
Query: 347 RAWKAEILS--LESRKELLVLKLEEAEKEAE 375
+A K + + R+E L KLEE K+ E
Sbjct: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEE 427
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 54.3 bits (129), Expect = 4e-07
Identities = 53/191 (27%), Positives = 98/191 (51%), Gaps = 12/191 (6%)
Query: 191 DQDSSSLKLSQNIAVQTDFKTA-DSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQ 249
D ++ ++ LSQ + KT + + N +++EK TE T ++ +EVL+ + Q
Sbjct: 1012 DGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQK-REVLETELQ 1070
Query: 250 -VENQLQVQLKQLQQRREEEMKNH---QEILKAIQDVTIKREETKKKIEKEKKEFLQKEQ 305
+L+ L+QLQ+ R+ K +E I+D+T + E K +IE +K+E L+ +Q
Sbjct: 1071 NAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQ 1130
Query: 306 DLKAEIEKLCEKGRREVWEMELD-RLKNQDGEINRNIMEETERAWKAEILSLESRKELLV 364
LK E+ E +R LD ++ GE+ + I++ K+E+ E K++
Sbjct: 1131 ALK---ERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIES 1187
Query: 365 L--KLEEAEKE 373
L KL+ A+++
Sbjct: 1188 LNDKLQNAKEQ 1198
Score = 40.4 bits (93), Expect = 0.006
Identities = 48/234 (20%), Positives = 101/234 (43%), Gaps = 23/234 (9%)
Query: 184 VRVDQDDDQDSSSLKLSQNIAVQTDF-KTADSEVNTDQDIEKNLDKMMTERTLLKER--- 239
+ + D + + + + SQ +Q + + A + + ++ K +++T L+E+
Sbjct: 653 IEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVA 712
Query: 240 YQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEK---- 295
Y + K ++E +L + ++++ H++I A + E K++EK
Sbjct: 713 YSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIER 772
Query: 296 -----EKKEFLQKEQDLKAEI---EKLCEKGRREVWEMELDRLKNQD-GEINRNIMEETE 346
EKK+ KEQ+ + + +C++ E LDRL + GE+ + M++ E
Sbjct: 773 LEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE----SLDRLLTESKGEMKKENMKKDE 828
Query: 347 --RAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWE 398
+A + ++ + L LE ++E LHL L+ E K+ E
Sbjct: 829 ALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEE 882
Score = 40.4 bits (93), Expect = 0.006
Identities = 45/190 (23%), Positives = 97/190 (51%), Gaps = 29/190 (15%)
Query: 237 KERYQEVLDKQRQ----VENQLQVQLKQLQQRREEEM---KNHQEILKAIQDVTIKR--- 286
KE++++ L K+ + ++ +L+++ LQ+ E+ + Q+ + +Q TI+
Sbjct: 869 KEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGEL 928
Query: 287 EETKKKIEKEKKEF---LQKEQDLKAE----IEKLCEKGRREVWEMELDRLKNQDGEINR 339
E+T+ K+EK+ + LQK+++ AE +E+ CE E +++ ++ G +
Sbjct: 929 EDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEA-DLKRQKVIELTGTARQ 987
Query: 340 NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWET 399
+E + +K E+ +E KE++ LK + K +HL+ L + ++K E E
Sbjct: 988 VKIEMDQ--YKEELSKME--KEIMHLKRDGENK--AMHLSQL-----DMILDQTKTELEK 1036
Query: 400 RLNGVRIMKK 409
+ N V+ ++K
Sbjct: 1037 KTNAVKELEK 1046
Score = 37.0 bits (84), Expect = 0.063
Identities = 45/188 (23%), Positives = 84/188 (44%), Gaps = 25/188 (13%)
Query: 201 QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTL-LKERYQEVLDKQRQVENQLQVQLK 259
Q I ++ + D + ++ + KM+ E+ L+E +E + + + Q + Q K
Sbjct: 292 QIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTK-QGK 350
Query: 260 QLQQRREEEMKNHQEILKAIQDVTIKREETKKKI--------------EKEKKEFLQKEQ 305
+ +++R E + N +E+ KA Q K E +K+ EKE K ++
Sbjct: 351 RAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCG 410
Query: 306 DLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVL 365
K+E+E L EK R+ + +N +G+ IM A++ ESR+ +L L
Sbjct: 411 LYKSELEILKEKLRQL-------KEENNNGKEKLRIMAVKNSEVMAQL--TESRQSILKL 461
Query: 366 KLEEAEKE 373
+ E K+
Sbjct: 462 ESELENKD 469
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 53.5 bits (127), Expect = 6e-07
Identities = 36/200 (18%), Positives = 102/200 (51%), Gaps = 8/200 (4%)
Query: 180 GVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQD--IEKNLDKMMTERTLLK 237
G G + +Q +Q+ K + + Q + E +Q+ ++K +++ + ++
Sbjct: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258
Query: 238 ERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK 297
++ +++ +++ Q+ Q + LKQ +Q +EE QE Q+ ++ +E +++ +++
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQE--EQMREQE 316
Query: 298 KEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQD--GEINRNIMEETERAWKAEILS 355
++ ++E+ + + E++ E+ + ++WE + K ++ GE + ++ E+ K E
Sbjct: 317 EQMREQEEQMGKQEEQMWEQ-KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE-EQ 374
Query: 356 LESRKELLVLKLEEAEKEAE 375
+ ++E + + E+ K+ E
Sbjct: 375 MRKQEEQMRKQEEQMRKQEE 394
Score = 46.2 bits (108), Expect = 1e-04
Identities = 39/203 (19%), Positives = 101/203 (49%), Gaps = 18/203 (8%)
Query: 187 DQDDDQDSSSLKLSQNIAVQTDF--KTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVL 244
+Q +Q+ K + + Q + K + ++ + K ++M + ++E+ +++L
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Query: 245 DKQRQVENQLQVQLKQLQQR-REEEMKNHQEILKAIQDVTIKREETKKKIEK-------- 295
++ Q E + Q ++ Q R +EE+M+ +E ++ ++ ++EE K E+
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
Query: 296 --EKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEI 353
E+KE + K+++ E E+ +K +V + E ++++ Q+ ++ + + E+ K E
Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE-EQMRKQEEQMRK----QEEQMRKQEE 394
Query: 354 LSLESRKELLVLKLEEAEKEAEL 376
E ++++ K + E+E ++
Sbjct: 395 QMGEQKEQMGEQKEQMREQEEQM 417
Score = 41.2 bits (95), Expect = 0.003
Identities = 38/188 (20%), Positives = 92/188 (48%), Gaps = 8/188 (4%)
Query: 183 GVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLL----KE 238
G + +Q Q+ K + + Q + E +Q+ + K TE+ +E
Sbjct: 237 GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
Query: 239 RYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEK--E 296
+ +E ++ R+ E Q++ Q +Q++++ E+ K +++ + + + ++E+ K+ E+ E
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
Query: 297 KKEFLQK--EQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEIL 354
++E +QK EQ K E + ++ + E ++ + + Q GE + E+ E+ + E
Sbjct: 357 QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416
Query: 355 SLESRKEL 362
E ++++
Sbjct: 417 MGEQKEQM 424
Score = 36.6 bits (83), Expect = 0.082
Identities = 40/182 (21%), Positives = 89/182 (48%), Gaps = 7/182 (3%)
Query: 236 LKERYQEVLDKQRQV-ENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIE 294
++E+ +V +++ QV E + QV+ ++ Q R +E QE Q+ + RE+ + E
Sbjct: 138 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV-REQEGQMGE 196
Query: 295 KEKKEFLQKEQDLKAEIEKLCEKGRREVWEME--LDRLKNQDGEINRNIMEETERAWKAE 352
+E + Q+EQ E E+ +K ++ E E + + + Q GE + ++ E+ K E
Sbjct: 197 QEGQMGEQEEQ--MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
Query: 353 ILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVR 412
+ ++E + + E+ ++ E L + T +T +++ + +R ++ +R
Sbjct: 255 -EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313
Query: 413 DQ 414
+Q
Sbjct: 314 EQ 315
Score = 36.2 bits (82), Expect = 0.11
Identities = 27/142 (19%), Positives = 70/142 (49%), Gaps = 4/142 (2%)
Query: 187 DQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDK 246
+Q +Q+ + + + Q + E +Q E+ + K + KE+ E ++
Sbjct: 289 EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ--EEQMGKQEEQMWEQKEQMWEQKEQ 346
Query: 247 QRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEK--EKKEFLQKE 304
+ E Q+ Q +Q+Q++ E+ K +++ K + + + E+ +K+ E+ E+KE + ++
Sbjct: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ 406
Query: 305 QDLKAEIEKLCEKGRREVWEME 326
++ E E+ + + ++ + E
Sbjct: 407 KEQMREQEEQMGEQKEQMRKQE 428
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 53.5 bits (127), Expect = 6e-07
Identities = 67/331 (20%), Positives = 151/331 (45%), Gaps = 42/331 (12%)
Query: 103 SGSQSDLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKE 162
S Q DL+ ++ A + D ++E L LK T R EK+ + S +++
Sbjct: 1752 SNMQKDLEH-SNDALKAQDLKIQEELRIAHMHLKEQQETIDKL-RGIVSEKTDKLSNMQK 1809
Query: 163 GNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTAD--------S 214
+++ + + E + D + + K+S+ ++ K
Sbjct: 1810 DLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIE 1869
Query: 215 EVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQE 274
+N Q + +NL++M ++++KER D R+VE L+++ QL++ +E E
Sbjct: 1870 NLNLAQKLHENLEEM---KSVMKER-----DNLRRVEETLKLERDQLKESLQETKARDLE 1921
Query: 275 I---LKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLK 331
I LK + ++ + +ET K+ ++ E + D++ +++K ++ ++++ E++ L+
Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQ 1981
Query: 332 ----NQDGEINR---NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKST 384
+D ++ N ME+ ++ ++A+ LS++S ++++ + +LH
Sbjct: 1982 LLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQS------VRMDNFQLTKKLH------- 2028
Query: 385 PPTLETVRSKQEWETRLNGVRIMKKNVRDQF 415
+LE +R + L ++ K RDQF
Sbjct: 2029 -ESLEEIRIVAKERDELRRIKESLKMERDQF 2058
Score = 47.8 bits (112), Expect = 4e-05
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 221 DIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQ 280
D ++ + +E LKE+ +E+ +Q+EN +Q+ QL+ +++ ++ +E+ A
Sbjct: 636 DAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFN 695
Query: 281 DVTIKREETKKKIEKE---KKEFLQKEQDLKAEIEKLCEKG---RREVWEMELDRLKNQD 334
++T K+ K+ E K DL+ E+ K E+ R EV + L LK+
Sbjct: 696 EITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEV--ILLSELKSLP 753
Query: 335 GEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRS 393
E+ R E +++ + I++ S K+ L ++ E + L + T L T +S
Sbjct: 754 SEVERLRKEIQDKSEELHIIT--SEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQS 810
Score = 47.8 bits (112), Expect = 4e-05
Identities = 56/226 (24%), Positives = 111/226 (49%), Gaps = 21/226 (9%)
Query: 205 VQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQV------ENQLQV-Q 257
++ + ++E++T I+K L+ + + L+ + QE+ +K+ Q E Q +V +
Sbjct: 1496 LRVNLSEKETEIST---IQKQLEAINDK---LQNKIQEIYEKEEQFNIKQISEVQEKVNE 1549
Query: 258 LKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIE---KEKKEFLQKEQDLKAEIEKL 314
LKQ ++ R+ + Q I + ++T + +E++++I+ KEK+E + ++ L+ E ++L
Sbjct: 1550 LKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQL 1609
Query: 315 CEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEA 374
E + V +M+ + K + + ET+ EI L+ + E L LE E E
Sbjct: 1610 KENTKEIVAKMKESQEKEYQ-FLKMTAVNETQEK-MCEIEHLKEQFETQKLNLENIETE- 1666
Query: 375 ELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ 420
+ LT + LE +RS + L V K RDQ +++
Sbjct: 1667 NIRLTQI--LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLR 1710
Score = 47.0 bits (110), Expect = 6e-05
Identities = 53/237 (22%), Positives = 110/237 (46%), Gaps = 22/237 (9%)
Query: 215 EVNTDQDIEKN---LDKMMTERTLLKERYQEVLDKQRQV--ENQLQVQLKQLQQRREEEM 269
E+ T+Q K+ L ++ ER L E++QE ++ + + E +K+ + + +++
Sbjct: 1309 ELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQL 1368
Query: 270 KNH-QEILKAIQDVTIKREET---------KKKIEKEKKEFLQKEQD-LKAEIEKLCEKG 318
K H +E L IQ+ K+E++ KI E ++F K+ L+ EIE L
Sbjct: 1369 KEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSK 1428
Query: 319 RREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHL 378
R + E+ + + ++ R + ++E L+ + +V K E E+E ++
Sbjct: 1429 RLQESHDEMKSVAKEKDDLQR-----LQEVLQSESDQLKENIKEIVAKHLETEEELKVAH 1483
Query: 379 TYLKSTPPTLETVR-SKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQI 434
LK T+ +R + E ET ++ ++ + + D+ + IQ + + ++ QI
Sbjct: 1484 CCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQI 1540
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/185 (23%), Positives = 89/185 (48%), Gaps = 18/185 (9%)
Query: 197 LKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQV 256
LK Q I Q + + + ++ + D++ LKE+ Q++ +KQ+Q+ N +Q
Sbjct: 1094 LKKQQEIVAQEK----NHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLN-VQE 1148
Query: 257 QLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCE 316
++ ++ Q++ E++N + LK +E T + +E E+ E QK + E++ + +
Sbjct: 1149 EMSEM-QKKINEIENLKNELK-------NKELTLEHMETERLELAQKLNENYEEVKSITK 1200
Query: 317 -----KGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAE 371
K ++ +E E D L+ EI ++ E A I E ++ + L+ +E
Sbjct: 1201 ERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 372 KEAEL 376
K A++
Sbjct: 1261 KTAQI 1265
Score = 46.2 bits (108), Expect = 1e-04
Identities = 73/330 (22%), Positives = 143/330 (43%), Gaps = 43/330 (13%)
Query: 109 LKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTS 168
+K+ ++ +RE+L + S +KQ S N E+ + T I+ E +
Sbjct: 1357 IKEALEVKHDQLKEHIRETLAKIQES-----QSKQEQSLNMKEKDNETTKIVSEMEQ--- 1408
Query: 169 LDFRPVVSPANGVE------GVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEV---NTD 219
F+P S +E R+ + D+ S K ++ + ++S+ N
Sbjct: 1409 --FKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIK 1466
Query: 220 QDIEKNLD---KMMTERTLLKERYQEVLDKQR----QVENQLQVQLKQLQQRREEEMKNH 272
+ + K+L+ ++ LKE+ +E +++ R + E ++ KQL+ ++
Sbjct: 1467 EIVAKHLETEEELKVAHCCLKEQ-EETINELRVNLSEKETEISTIQKQLEAINDKLQNKI 1525
Query: 273 QEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL-DRLK 331
QEI + + IK+ ++ E K+F + + + ++ + K +EL +RL+
Sbjct: 1526 QEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESK------MLELTNRLQ 1579
Query: 332 NQDGEINRNIMEETERAWKAEILSL------ESRKELLVLKLEEAEKEAE-LHLTYLKST 384
EI I E+ E E L + E+ KE++ E EKE + L +T + T
Sbjct: 1580 ESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNET 1639
Query: 385 PPTL-ETVRSKQEWET-RLNGVRIMKKNVR 412
+ E K+++ET +LN I +N+R
Sbjct: 1640 QEKMCEIEHLKEQFETQKLNLENIETENIR 1669
Score = 40.4 bits (93), Expect = 0.006
Identities = 44/192 (22%), Positives = 92/192 (47%), Gaps = 27/192 (14%)
Query: 216 VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQV--QLKQLQQRREEEMKNHQ 273
VN ++ +K + +T L + QE+ +K R+V+ +L QLK+ + R+ ++ +
Sbjct: 848 VNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVE 907
Query: 274 EILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQ 333
++ T+ E+ ++ +E E K Q++ DLK E L ++E D+LK+
Sbjct: 908 ------REKTLITEKLQQTLE-EVKTLTQEKDDLKQLQESL---------QIERDQLKSD 951
Query: 334 -DGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVR 392
+N NI +T+ + + SL+ +E + + +E +L ++T T
Sbjct: 952 IHDTVNMNI--DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET----- 1004
Query: 393 SKQEWETRLNGV 404
K E++ ++ G+
Sbjct: 1005 -KDEFQQKMVGI 1015
Score = 33.9 bits (76), Expect = 0.53
Identities = 30/139 (21%), Positives = 73/139 (52%), Gaps = 14/139 (10%)
Query: 226 LDKMMTERTLLKERYQEVLDKQRQVEN-QLQVQLKQLQQRREEEMKNHQEILKAIQDVTI 284
++++ T+ LLK +E++D ++Q+E L+ + + +++ + ++ +++L+ +Q+ I
Sbjct: 335 VNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKI 394
Query: 285 KREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEM-ELDRLKNQDGEINRNIME 343
+ T+ + L +Q+LKA ++ RR W + +++++KN + NI
Sbjct: 395 E-NLTRMLVTSSS---LTLQQELKA------KRKRRVTWCLGKINKMKNSNYADQFNI-- 442
Query: 344 ETERAWKAEILSLESRKEL 362
T K LS+ +E+
Sbjct: 443 PTNITTKTHKLSINLLREI 461
Score = 32.7 bits (73), Expect = 1.2
Identities = 52/287 (18%), Positives = 111/287 (38%), Gaps = 37/287 (12%)
Query: 106 QSDLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNR 165
+ +L+ V T E D L+ESL T++ + +R S+E L+E
Sbjct: 1891 RDNLRRVEETLKLERD-QLKESLQE-TKARDLEIQQELKTARMLSKEHKETVDKLREKIS 1948
Query: 166 DTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLS-------QNIAVQTDFKTADSEVNT 218
+ ++ + ++ D D +D K+ Q + V+ D + ++N
Sbjct: 1949 EKTIQ----------ISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINE 1998
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRR--EEEMKNHQEIL 276
+ ++K + ++ ++ K + ++++ K+ + R +E +K ++
Sbjct: 1999 MEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQF 2058
Query: 277 KAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGE 336
A I R+ +++ EK+ +Q L + + C R+K E
Sbjct: 2059 IATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKC------------SRIK----E 2102
Query: 337 INRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKS 383
+ + E + LSL+ KE+ K +A L L YL++
Sbjct: 2103 LLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQT 2149
Score = 32.0 bits (71), Expect = 2.0
Identities = 40/213 (18%), Positives = 91/213 (42%), Gaps = 34/213 (15%)
Query: 216 VNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVE------------NQLQVQLKQLQQ 263
+ +++++ + + ER LKE +E++ K ++ + N+ Q ++ +++
Sbjct: 1589 IKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEH 1648
Query: 264 RREE------EMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEK 317
+E+ ++N + + + + E + + KE+ + E+ LK E ++L ++
Sbjct: 1649 LKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL-KE 1707
Query: 318 GRREVWEMELDR----------LKNQDGEIN--RNIMEETERAWKAEILSLESRKELLV- 364
RE +L++ LK I+ R I+ E LE + L
Sbjct: 1708 NLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKA 1767
Query: 365 --LKLEEAEKEAELHLTYLKSTPPTLETVRSKQ 395
LK++E + A +HL + T L + S++
Sbjct: 1768 QDLKIQEELRIAHMHLKEQQETIDKLRGIVSEK 1800
Score = 31.2 bits (69), Expect = 3.4
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 11/150 (7%)
Query: 232 ERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKK 291
E+ LL + Q + + R+ ++++ LK R EM +H E L + K E +K
Sbjct: 2078 EKRLLSDGQQHLTESLREKCSRIKELLK-----RYSEMDDHYECLNRLSLDLEKEIEFQK 2132
Query: 292 KIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEME--LDRLKNQDGEINRNIMEETERAW 349
++ K L IEKL +R E + +LK + + E+ E
Sbjct: 2133 ELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESIN 2192
Query: 350 KAE---ILSLESRKELLVLKLEEAEKEAEL 376
K E I +E +KELL+ K++ +++ ++
Sbjct: 2193 KFEMDFIDEVEKQKELLI-KIQHLQQDCDV 2221
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 53.5 bits (127), Expect = 6e-07
Identities = 62/248 (25%), Positives = 113/248 (45%), Gaps = 21/248 (8%)
Query: 185 RVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERY---Q 241
R + +++ ++ +++ Q A S +++ L++ T L+ER +
Sbjct: 700 RAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQK 759
Query: 242 EVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKK--IEKEKKE 299
EVL+ E + + + ++R+ ++++NH K I + I E+ K K +EKEKK
Sbjct: 760 EVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKK- 818
Query: 300 FLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESR 359
K QDL+ + K +K E+ E + D L N+ + ++EET++ E L ES
Sbjct: 819 ---KVQDLENRLTK--QKEELELKEQKEDVLNNKLSDA-LAMVEETQKTKATESLKAES- 871
Query: 360 KELLVLKLEEAEKEAELHLTYLKSTPPTL----ETVRSKQ-EWETRLNGVRIMKKNVRDQ 414
L LKL E E E T + L + V++ Q E E++ +G ++Q
Sbjct: 872 ---LALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQ 928
Query: 415 FNSHIQLV 422
H Q +
Sbjct: 929 IKQHAQTI 936
Score = 37.4 bits (85), Expect = 0.048
Identities = 61/358 (17%), Positives = 142/358 (39%), Gaps = 22/358 (6%)
Query: 52 VSSQTITKENNRNVHLEHSEQNPGSSAGDT---SAAHQVVLGENLIATALCLSGSGSQSD 108
VS T +++N + + + + A S Q+ + + LC + S S+
Sbjct: 268 VSETTTSRQNEKEISQKCQVLDEDIDAKQKEIQSLKSQISALQKGYSKVLCQTLSERNSE 327
Query: 109 LKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTS 168
+ + + EG+ R++ +T + + LA ++ + S LK N+D
Sbjct: 328 ITSLKN----EGENLKRDNA--ITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKD 381
Query: 169 LDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDK 228
+ S + ++ +D ++ + + +T + + E+ + + L K
Sbjct: 382 HQLEALGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQDMEKEM---KKLRAELRK 438
Query: 229 MMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREE 288
TE++++ +E + +++ + +L QLQ+ E + +A+ + R +
Sbjct: 439 SCTEQSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNRESVIKINLERAVGQLEHFRSQ 498
Query: 289 TKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERA 348
K K F K + IEK+ + + + ++ +++ + EET
Sbjct: 499 VIKATYGRAKPFRDKPVTDQQLIEKITQVTEDNINFQQKKWTLQKETQLSNSKQEETTEN 558
Query: 349 WKAEILSLESRKELLVLKL--EEAEKEAELHLTYLKSTPP-------TLETVRSKQEW 397
+ SL+S + + + + +KE +L L +L+ +PP L+ +R W
Sbjct: 559 IEKLRTSLDSCQACMKISCCSHDLKKEVDL-LQHLQVSPPVSGLQKVVLDVLRHALSW 615
Score = 37.0 bits (84), Expect = 0.063
Identities = 46/252 (18%), Positives = 105/252 (41%), Gaps = 30/252 (11%)
Query: 26 KSDEGLPDGLSTKDSAQKQKN--SPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSA 83
K EG L D A K++ PL++ +T+ + +++ EH D A
Sbjct: 951 KKIEGEIATLKDNDPAPKEERPQDPLVA----PMTESSAKDMAYEHL-------IDDLLA 999
Query: 84 AHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQ 143
A + +L + + L + + S + D+ E+ L +++ V + K K+
Sbjct: 1000 AQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKE 1059
Query: 144 LASRNCS--EEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQ 201
++ S E+K + L+E R + E R+ + +++ K +Q
Sbjct: 1060 KMAQMSSLVEKKDRELKALEEALRASQ-------------EKHRLQLNTEKEQKPRKKTQ 1106
Query: 202 NIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQL 261
+ +E + +++ + R++EV+ +Q++ ++L+ ++K+L
Sbjct: 1107 TCDTSVQIEPVHTEAFSSSQEQQSFSDLGVR--CKGSRHEEVIQRQKKALSELRARIKEL 1164
Query: 262 QQRREEEMKNHQ 273
++ R + K+HQ
Sbjct: 1165 EKARSPDHKDHQ 1176
Score = 30.8 bits (68), Expect = 4.5
Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 18/109 (16%)
Query: 208 DFKTADSEVNTDQDIEKNLDKMMTE--------RTLLKERYQEVLD----------KQRQ 249
D A E+ + Q++ L K +TE R L E+ + L+ K+
Sbjct: 996 DLLAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELS 1055
Query: 250 VENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKK 298
V + Q+ L ++++ E+K +E L+A Q+ + T+K+ + KK
Sbjct: 1056 VLKEKMAQMSSLVEKKDRELKALEEALRASQEKHRLQLNTEKEQKPRKK 1104
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 53.1 bits (126), Expect = 8e-07
Identities = 73/306 (23%), Positives = 131/306 (42%), Gaps = 51/306 (16%)
Query: 106 QSDLKDVASTAGEEGDTS--LRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEG 163
Q L++ E DT+ LR+S +++S+ QL S N E + IL+
Sbjct: 544 QKQLEEANDLLRTESDTAVRLRKSHTEMSKSIS------QLESLN--RELQERNRILENS 595
Query: 164 NRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIE 223
T D+ + + +E R D+ D + ++ ++Q + K ++
Sbjct: 596 KSQTDKDYYQLQAI---LEAERRDRGHDSEMIGDLQARITSLQEEVK----------HLK 642
Query: 224 KNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVT 283
NL+K+ ER ++ ++ +E L +LK LQQR E+E+ H+ + D
Sbjct: 643 HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKH 702
Query: 284 IKREETK-------KKIEKEKKEFLQKEQDLKAEIEKLCE----------------KGRR 320
EE K +K KE++E +K ++ +IEK C G +
Sbjct: 703 QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNK 762
Query: 321 EVWEMELDRLKNQ-DGEINRNIMEETE---RAWKAEIL-SLESRKELLVLKLEEAEKEAE 375
E E E+ L Q + E N+ ++ + E +A++A+ L LE + + + L EA++ E
Sbjct: 763 ERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLE 822
Query: 376 LHLTYL 381
L L
Sbjct: 823 FELAQL 828
Score = 43.9 bits (102), Expect = 5e-04
Identities = 47/201 (23%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 191 DQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQV 250
+Q+S+ L QN ++T AD+ ++ +++ ++ ++ + LL+ ++ + R
Sbjct: 777 EQESNKRLLLQN-ELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGN 835
Query: 251 ENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIE--KEKKEFLQKEQDL- 307
E Q++ QL+ + ++ + +++ K E KKI+ + +KE L + DL
Sbjct: 836 EGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLA 895
Query: 308 --KAEIEKLCEKGRREVWEMELDRLKNQDGEINR----------NIMEETERAWKAEILS 355
KAE E+L +G E EL + + NR + +EE +I
Sbjct: 896 ETKAESEQLA-RGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEI 954
Query: 356 LESRKELLVLKLEEAEKEAEL 376
L E L K+++AE+E +L
Sbjct: 955 LRRENEELTEKMKKAEEEYKL 975
Score = 35.0 bits (79), Expect = 0.24
Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 15/184 (8%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKA 278
D N DK + E +L K Y+ + Q+ N++Q++ + Q+ R +K +I+K
Sbjct: 413 DNRTSSNADKSLQE-SLQKTIYK----LEEQLHNEMQLKDEMEQKCRTSNIK-LDKIMKE 466
Query: 279 IQDVTIKR---EETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG 335
+ + +R E T +IEKEK + + + + E+ EK RR V E E+ LK+Q
Sbjct: 467 LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEK-RRNV-ENEVSTLKDQLE 524
Query: 336 E---INRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVR 392
+ +++N E+ + + LE +LL + + A + + H KS R
Sbjct: 525 DLKKVSQNSQLANEKLSQLQ-KQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 583
Query: 393 SKQE 396
QE
Sbjct: 584 ELQE 587
Score = 33.5 bits (75), Expect = 0.69
Identities = 35/182 (19%), Positives = 79/182 (43%), Gaps = 25/182 (13%)
Query: 218 TDQD-----IEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNH 272
TD+D +E+ + + +L+ +E+ +K ++ E + +++ +EEE+ N
Sbjct: 932 TDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLE-------KEEEISN- 983
Query: 273 QEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKN 332
LKA + I E T K K + +D K + R++ +L + +
Sbjct: 984 ---LKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKID--------RKKANTQDLRKKEK 1032
Query: 333 QDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVR 392
++ ++ + +E E+ + + + ++ +EE EL + L S +E +R
Sbjct: 1033 ENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQM-QLASKESDIEQLR 1091
Query: 393 SK 394
+K
Sbjct: 1092 AK 1093
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 53.1 bits (126), Expect = 8e-07
Identities = 39/200 (19%), Positives = 106/200 (53%), Gaps = 15/200 (7%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQL-KQLQQRREEEMK-NHQEIL 276
++ I++ +K+ + ++E+ +++ +++ ++ Q ++ K+ + RR+EEM +E +
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 277 KAIQDVTIKREETKKKIEKE--KKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQD 334
+ +++ ++EE +++E++ ++E ++++++ + E EK+ E+ +R+ E ++ R + +
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 335 GEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSK 394
E I E+ E+ W+ E E K+ E EK E + + E +R +
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQE------KIREEEKRQEQEEMWRQE-----EKIREQ 535
Query: 395 QEWETRLNGVRIMKKNVRDQ 414
+E + + ++ +R Q
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQ 555
Score = 46.6 bits (109), Expect = 8e-05
Identities = 28/167 (16%), Positives = 88/167 (52%), Gaps = 16/167 (9%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKA 278
++ I + +K+ + ++E+ +++ +++ ++ Q ++ +Q ++ E+E K ++ K
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK- 628
Query: 279 IQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG--E 336
+Q+ K ++KI +++K+ ++E+ ++ E E++ ++ ++WE E + ++ E
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 337 INRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKS 383
+ + E+ W+ E+ +L + E++ + H +L++
Sbjct: 688 QEEKMRRQEEKMWEQEV------------RLRQQEEKMQEHQEHLEA 722
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/196 (25%), Positives = 96/196 (48%), Gaps = 25/196 (12%)
Query: 201 QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQ-----EVLDKQRQ-VENQL 254
+N +Q + +SE + Q K L + + LL + Q + L K+ Q V +L
Sbjct: 283 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 342
Query: 255 QVQLKQ------LQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLK 308
Q Q+++ L Q++EE+M +E IQ+ K +E ++KI +++++ ++E+ ++
Sbjct: 343 QAQVEENELWNRLNQQQEEKMWRQEE---KIQEWEEKIQEQEEKIREQEEKIREQEEKMR 399
Query: 309 AEIEKLCEKG---RRE---VWEMELDRLKNQD---GEINRNIMEETERAWKAEILSLESR 359
+ E + EK RR+ +WE E ++++ Q+ E I E E+ + E + +
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 360 KELLVLKLEEAEKEAE 375
K K+ E EK E
Sbjct: 459 KRQEEEKIREQEKRQE 474
Score = 43.9 bits (102), Expect = 5e-04
Identities = 33/137 (24%), Positives = 77/137 (56%), Gaps = 22/137 (16%)
Query: 224 KNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQ-----RREEEMKNHQEILKA 278
+ L++ M E+ ++E+ +++RQ E +++ Q K+ +Q R+EE+++ +E ++
Sbjct: 441 RELEEKMHEQEKIREQ-----EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495
Query: 279 IQDVTIKREE---TKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG 335
++ ++EE ++KI +E+K Q+++++ + EK+ E + E+W R K +
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKR--QEQEEMWRQEEKIRE--QEEIW-----RQKEKIH 546
Query: 336 EINRNIMEETERAWKAE 352
E I ++ E+ W+ E
Sbjct: 547 EQEEKIRKQEEKMWRQE 563
Score = 43.5 bits (101), Expect = 7e-04
Identities = 34/193 (17%), Positives = 100/193 (51%), Gaps = 13/193 (6%)
Query: 182 EGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQD-IEKNLDKMMTERTLLKERY 240
E +R ++ + + + I Q + +++ ++ I K +KM + + ++
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 241 QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF 300
+++ +++ +V Q + +Q ++ RE+E K ++ + Q+ K E ++K+ +++++
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE-EMTQEQEEKMGEQEEKMCEQEEKM 629
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRK 360
++E+ ++ + EK+ E+ +++ E E ++++ Q+ + E+ E+ W+ E E +
Sbjct: 630 QEQEEKMRRQEEKIREQ-EKKIREQE-EKIREQE----EMMQEQEEKMWEQEEKMCEQEE 683
Query: 361 ELLVLKLEEAEKE 373
K++E E++
Sbjct: 684 -----KMQEQEEK 691
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/186 (17%), Positives = 97/186 (52%), Gaps = 17/186 (9%)
Query: 201 QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQ 260
+ I Q + + + ++ + ++ KM + ++E+ +++ +++ ++ Q + ++ +
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ-EEKIHE 509
Query: 261 LQQRREEEMKNHQEILKAIQDVTIKRE----------ETKKKIEKEKKEFLQKEQDLKAE 310
++ REEE + QE + ++ ++E E ++KI K++++ ++E+ + +
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 311 IEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEA 370
EK+ E+ +VW E ++++ Q+ I E+ E+ + E ++ E +++ + +
Sbjct: 570 EEKIREQ-EEKVWRQE-EKIREQE----EKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 371 EKEAEL 376
E+E ++
Sbjct: 624 EQEEKM 629
Score = 41.2 bits (95), Expect = 0.003
Identities = 44/220 (20%), Positives = 100/220 (45%), Gaps = 28/220 (12%)
Query: 213 DSEVNTDQDIEKNLDKMMTERTLLKERYQEVL-DKQRQVENQLQVQLKQLQQRREEEMKN 271
+ ++ ++ + ++MM E+ R +E++ +K+ ++ Q ++ ++ ++ RE E K
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447
Query: 272 HQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRRE---------- 321
H++ RE+ +K+ E+EK +K Q+ +A++ + EK R +
Sbjct: 448 HEQ--------EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 322 VWEMELDRLKNQDGEINRNIMEETERAWKAEILSLES-----RKELLVLKLEEAEKEAEL 376
+W E +++ Q+ +E E W+ E E +KE + + E+ K+ E
Sbjct: 500 MWRQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
Query: 377 HLTYLKSTPPTLETVRSKQE--WETRLNGVRIMKKNVRDQ 414
+ E +R ++E W +R ++ +R+Q
Sbjct: 559 MWRQEEKMHDQEEKIREQEEKVWRQE-EKIREQEEKIREQ 597
Score = 40.8 bits (94), Expect = 0.004
Identities = 39/203 (19%), Positives = 99/203 (48%), Gaps = 9/203 (4%)
Query: 182 EGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLL---KE 238
E +R ++ ++ Q + K + E +Q+ ++ + E+ + KE
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 239 RYQEVLDKQRQVENQLQVQLKQLQQR----REEEMKNHQEILKAIQDVTIKREETKKKIE 294
+ E +K R+ E ++ Q +++ + RE+E K ++ K I++ K E ++KI
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK-IREQEEKIREQEEKIR 602
Query: 295 KEKKEFLQKEQDLKAEIEKLCEKGRR-EVWEMELDRLKNQDGEINRNIMEETERAWKAEI 353
++++ ++E+ + + EK+CE+ + + E ++ R + + E + I E+ E+ + E
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 354 LSLESRKELLVLKLEEAEKEAEL 376
+ E +++ + + E+E ++
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKM 685
Score = 40.0 bits (92), Expect = 0.007
Identities = 40/162 (24%), Positives = 77/162 (47%), Gaps = 10/162 (6%)
Query: 221 DIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQ 280
++E+ L + T++ +RY E L K+R + + + +E+ QE L+ ++
Sbjct: 237 ELEQALSAVATQKKKA-DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 295
Query: 281 ----DVTIKREETKKKIEKEK----KEFLQKEQD-LKAEIEKLCEKGRREVWEMELDRLK 331
++ + +E K+K+E+ K ++ LQ E D L E++ + K + +V E EL
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 332 NQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKE 373
NQ E EE + W+ +I E + K+ E E++
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Score = 39.7 bits (91), Expect = 0.010
Identities = 43/216 (19%), Positives = 105/216 (48%), Gaps = 20/216 (9%)
Query: 213 DSEVNTDQDIEKNLDKMMTERTLLK-ERYQEVLDKQRQVENQLQVQLKQLQQRRE----E 267
+ +++ + I + +K E + + E+ QE K + E +++ Q ++++++ E +
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 268 EMKNHQEILKAIQDVTIKREETKKKIEK--EKKEFLQKEQDLKAEIEKLCEKGRREVWEM 325
E K H++ ++ ++EE ++ EK E++E ++++ + + EK+ K ++W
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI-RKQEEKMWRQ 562
Query: 326 ELDRLKNQDGEINRNIMEETERAWKAEILSLESRKEL-----LVLKLEEAEKEAELHLTY 380
E +++ +Q+ I E+ E+ W+ E E +++ + + EE +E E +
Sbjct: 563 E-EKMHDQE----EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 381 LKSTPPTLETVRSKQEWETRL--NGVRIMKKNVRDQ 414
+ E +QE + R +R +K +R+Q
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653
Score = 29.6 bits (65), Expect = 10.0
Identities = 40/239 (16%), Positives = 106/239 (44%), Gaps = 16/239 (6%)
Query: 187 DQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDK 246
++ +Q++ + + I Q + K + E + EK ++ ++ +E+ +
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEE-KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 528
Query: 247 QRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEK-----KEFL 301
+ ++ Q ++ ++ + +EE QE Q+ + +E K + ++EK ++
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 302 QKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG---EINRNIMEETERAWKAEILSLES 358
++E+ ++ + EK+ E + E+ + + +++ Q+ E + E+ E+ + E E
Sbjct: 589 EQEEKIREQEEKIRE--QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 359 RKEL-----LVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVR 412
K++ + + EE +E E + + E +QE + R ++ ++ VR
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 705
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.8 bits (125), Expect = 1e-06
Identities = 40/187 (21%), Positives = 97/187 (51%), Gaps = 16/187 (8%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQ---EI 275
D+ I++ ++M + ++E+ ++ +K + E +++ Q ++++++ EE + + E+
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIREL 439
Query: 276 LKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG 335
+ +QD K E ++K+++E+++ ++E+ ++ + EK+ E+ + W E +L Q+
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ-EEKTWRQE--KLLKQE- 495
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSK- 394
I E+ E+ W+ E E + K++E E++ + ++ L K
Sbjct: 496 ---EKIWEQEEKMWRQEEKMWEQEE-----KMQEQEEKMQRQEEKMREQEVRLWQQEEKM 547
Query: 395 QEWETRL 401
QE E RL
Sbjct: 548 QEQEVRL 554
Score = 49.3 bits (116), Expect = 1e-05
Identities = 47/233 (20%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQV---ENQLQVQLKQLQQRREEEMKNHQEI 275
++ I + DKM + ++E+ +++ +++ ++ E +++ Q +++Q++ EE + ++I
Sbjct: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
Query: 276 LKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKL---------CEKGRREVWEM- 325
+ + K +KK+ ++ ++ ++E+++ + EK+ E+ REV E
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 326 --ELDRLKNQDGEINR---NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTY 380
E ++++ Q+ +I R I E+ E+ W+ E L + K + + EE E +
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK---IWEQEEKMWRQEEKMWE 514
Query: 381 LKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQ 433
+ E +QE + R VR+ ++ + Q ++L +L L Q
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQ-EQEVRLQELEERLGKLGQ 566
Score = 45.8 bits (107), Expect = 1e-04
Identities = 60/299 (20%), Positives = 129/299 (43%), Gaps = 44/299 (14%)
Query: 115 TAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSI---------LKEGNR 165
TA + + SL E +++ G + ++L E +P + LKE N
Sbjct: 166 TAQKRPENSLLEETLHFDHAVRMGTYIEKLTK----ERDAPSLELYRNTITDEELKEKNA 221
Query: 166 DTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKL-SQNIAVQTD-------FKTADSEVN 217
+ R V S + ++ D + + L L Q + V+ D +A +
Sbjct: 222 ELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ 281
Query: 218 TDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILK 277
+++ NL E + ++ + +++ E +L+++ ++ + R+EE + QE
Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKI 341
Query: 278 AIQDVTIKREETK-----KKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKN 332
Q+ + R+E K +KI +++++ ++E+ ++ + EK+ E+ E+W E ++++
Sbjct: 342 REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ-EEEMWRQE-EKIRE 399
Query: 333 QD--------------GEINRNIMEETERAWKAE--ILSLESRKELLVLKLEEAEKEAE 375
Q+ E + I E+ E W+ E I LE + KL E E++ +
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/184 (21%), Positives = 96/184 (52%), Gaps = 15/184 (8%)
Query: 187 DQDDDQDSSSLKLSQNIAVQTD-FKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLD 245
+Q++ + + + + Q + + + E+ ++ + L++MM ++ +E+ +EV +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ---EEKLREVEE 455
Query: 246 KQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKRE----ETKKKIEKEKKEFL 301
K ++ E ++Q Q +++Q R+EE QE Q+ +K+E E ++K+ +++++
Sbjct: 456 KMQEEEEKMQEQEEKIQ--RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMW 513
Query: 302 QKEQDLKAEIEKLC---EKGRREVWEMELDRLKNQDGEINRNIMEET--ERAWKAEILSL 356
++E+ ++ + EK+ EK R + + K Q+ E+ +EE + KAE+L
Sbjct: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
Query: 357 ESRK 360
R+
Sbjct: 574 AGRE 577
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.8 bits (125), Expect = 1e-06
Identities = 40/187 (21%), Positives = 97/187 (51%), Gaps = 16/187 (8%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQ---EI 275
D+ I++ ++M + ++E+ ++ +K + E +++ Q ++++++ EE + + E+
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIREL 439
Query: 276 LKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDG 335
+ +QD K E ++K+++E+++ ++E+ ++ + EK+ E+ + W E +L Q+
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ-EEKTWRQE--KLLKQE- 495
Query: 336 EINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSK- 394
I E+ E+ W+ E E + K++E E++ + ++ L K
Sbjct: 496 ---EKIWEQEEKMWRQEEKMWEQEE-----KMQEQEEKMQRQEEKMREQEVRLWQQEEKM 547
Query: 395 QEWETRL 401
QE E RL
Sbjct: 548 QEQEVRL 554
Score = 49.3 bits (116), Expect = 1e-05
Identities = 47/233 (20%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 219 DQDIEKNLDKMMTERTLLKERYQEVLDKQRQV---ENQLQVQLKQLQQRREEEMKNHQEI 275
++ I + DKM + ++E+ +++ +++ ++ E +++ Q +++Q++ EE + ++I
Sbjct: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
Query: 276 LKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKL---------CEKGRREVWEM- 325
+ + K +KK+ ++ ++ ++E+++ + EK+ E+ REV E
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 326 --ELDRLKNQDGEINR---NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTY 380
E ++++ Q+ +I R I E+ E+ W+ E L + K + + EE E +
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK---IWEQEEKMWRQEEKMWE 514
Query: 381 LKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQ 433
+ E +QE + R VR+ ++ + Q ++L +L L Q
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQ-EQEVRLQELEERLGKLGQ 566
Score = 45.1 bits (105), Expect = 2e-04
Identities = 60/295 (20%), Positives = 131/295 (44%), Gaps = 36/295 (12%)
Query: 115 TAGEEGDTSLRESLHPVTRSLKAGCHTKQLAS-RNCSEEKSPQTSI----LKEGNRDTSL 169
TA + + SL E +++ G + ++L R+ + + +I LKE N +
Sbjct: 166 TAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQE 225
Query: 170 DFRPVVSPANGVEGVRVDQDDDQDSSSLKL-SQNIAVQTD-------FKTADSEVNTDQD 221
R V S + ++ D + + L L Q + V+ D +A + +++
Sbjct: 226 KLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEEN 285
Query: 222 IEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQD 281
NL E + ++ + +++ E +L+++ ++ + R+EE + QE Q+
Sbjct: 286 ELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE 345
Query: 282 VTIKREETK-----KKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQD-- 334
+ R+E K +KI +++++ ++E+ ++ + EK+ E+ E+W E ++++ Q+
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ-EEEMWRQE-EKIREQEEK 403
Query: 335 ------------GEINRNIMEETERAWKAE--ILSLESRKELLVLKLEEAEKEAE 375
E + I E+ E W+ E I LE + KL E E++ +
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/184 (21%), Positives = 96/184 (52%), Gaps = 15/184 (8%)
Query: 187 DQDDDQDSSSLKLSQNIAVQTD-FKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLD 245
+Q++ + + + + Q + + + E+ ++ + L++MM ++ +E+ +EV +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ---EEKLREVEE 455
Query: 246 KQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKRE----ETKKKIEKEKKEFL 301
K ++ E ++Q Q +++Q R+EE QE Q+ +K+E E ++K+ +++++
Sbjct: 456 KMQEEEEKMQEQEEKIQ--RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMW 513
Query: 302 QKEQDLKAEIEKLC---EKGRREVWEMELDRLKNQDGEINRNIMEET--ERAWKAEILSL 356
++E+ ++ + EK+ EK R + + K Q+ E+ +EE + KAE+L
Sbjct: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
Query: 357 ESRK 360
R+
Sbjct: 574 AGRE 577
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.8 bits (125), Expect = 1e-06
Identities = 59/246 (23%), Positives = 116/246 (47%), Gaps = 29/246 (11%)
Query: 182 EGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTD------QDIEKNLDKMMTERTL 235
E R +Q +Q+ +L + + D+ + E Q ++++ ++ ER L
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 236 LKERYQEVLDKQRQVENQL---QVQLKQLQQRREEEMKNHQEILKAIQDV---------- 282
E +E ++Q + E QL Q + ++ + +R+EE + Q+ L++ Q +
Sbjct: 490 KLEE-EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 283 TIKREETKKKIEKEKKEFLQKEQD------LKAEIEKLCEKGRREVWEMELDRLKNQDGE 336
+KREE K+ ++ +++ L++EQ+ LK E E+ ++ +RE E RLK + E
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE--E 606
Query: 337 INRNIMEE-TERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQ 395
+ R EE E+ K E E R++LL + +E ++ +L + L+ ++
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 396 EWETRL 401
E RL
Sbjct: 667 RLEQRL 672
Score = 52.0 bits (123), Expect = 2e-06
Identities = 62/279 (22%), Positives = 130/279 (46%), Gaps = 33/279 (11%)
Query: 142 KQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQ 201
KQ R+ EE+ + L+E R + R + +R +Q++ ++ + +
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERRE--------QQLRREQEERREQRLKRQEE 524
Query: 202 NIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQL 261
+Q ++ ++ + L K E+ L +ER ++ L +R+ E + LK+
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL--KREQEERRDQLLKRE 582
Query: 262 QQRREEEMKNHQEILKAIQDVTIKREETKK---------KIEKEKKEFLQKEQDLKAE-- 310
++RR++ +K QE + +KREE ++ ++++E+ E +++Q LK+E
Sbjct: 583 EERRQQRLKREQE---ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 311 IEKLCEKGRREVWEMELDRLKNQDGE--INRNIMEETERAWKAEILSLESR---KELLVL 365
E+ ++ RRE E RLK ++ E + + + E E + + L+ E + +E +
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 366 KLE----EAEKEAELHLTYLKSTPPTLETVRSKQEWETR 400
++ + E EA+ + + S P E R +QE E +
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/177 (22%), Positives = 93/177 (52%), Gaps = 15/177 (8%)
Query: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Q+ E+ L + E+ +E+ ++ ++++ + + Q+ ++ ++RR +E + K +
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 280 Q--DVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLC----EKGRREVWEMEL---DRL 330
Q + + EE +K+ +E+++ ++E++L+ E E+L EK RR+ WE + D L
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 331 KNQDGEI-----NRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLK 382
+ ++ ++ + ++E ER ++ E L+ +E L+ + E + EL Y K
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREE-EELQQEEEQLLGEERETRRRQELERQYRK 1082
Score = 51.2 bits (121), Expect = 3e-06
Identities = 59/247 (23%), Positives = 121/247 (48%), Gaps = 11/247 (4%)
Query: 182 EGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQ 241
E R +Q +++ + Q + + E +Q + + ++ E+ L +E+ +
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 242 EVLDKQRQVENQL--QVQLKQLQQ-RREEEMKNHQEILKAIQDVTIKREETKKKIEKEKK 298
E ++Q + E QL + QL++ QQ RRE++++ Q++ + Q ++RE+ ++ ++ ++
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ---LRREQQLRREQQLRR 427
Query: 299 EFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLES 358
E ++ + K E E+ ++ +RE E D LK ++ E R+ E ++ K + E
Sbjct: 428 EQEEERHEQKHEQERREQRLKRE-QEERRDWLKREE-ETERHEQERRKQQLKRD-QEEER 484
Query: 359 RKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSK-QEWETRL-NGVRIMKKNVRDQFN 416
R+ L L+ EE ++ E L+ R K QE E RL +R ++ R+Q
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 417 SHIQLVR 423
QL++
Sbjct: 545 RREQLLK 551
Score = 50.8 bits (120), Expect = 4e-06
Identities = 60/274 (21%), Positives = 119/274 (43%), Gaps = 24/274 (8%)
Query: 142 KQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQ 201
++ R +E+ + + +E R + +R +Q++++ L+ Q
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 202 NIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQL 261
+ + + + ++ +Q + + ++ E+ L +E+ + R+ + + + + K
Sbjct: 382 QLRREQQLRR-EQQLRREQQLRRE-QQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 262 QQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE-KKEFLQKEQD-------LKAEIEK 313
Q+RRE+ +K QE + +KREE ++ E+E +K+ L+++Q+ LK E E+
Sbjct: 440 QERREQRLKREQEERRD----WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 314 LCEKG-------RREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLK 366
E+ RRE E RLK Q+ E +E+ + E E R+E L+ +
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE---QEERREQLLKR 552
Query: 367 LEEAEKEAELHLTYLKSTPPTLETVRSKQEWETR 400
EE E E LK K+E E R
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Score = 50.4 bits (119), Expect = 5e-06
Identities = 48/245 (19%), Positives = 116/245 (47%), Gaps = 17/245 (6%)
Query: 188 QDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQ 247
Q++++ L+ + + + + + +Q + + K ER +E +E +++
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR---KQEEERREQQEERREQQERR 328
Query: 248 RQVENQLQVQLKQLQQ-RREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQD 306
Q E + + QL++ Q+ RRE++++ QE + Q + ++EE +++ + +++ L++EQ
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 307 LKAEIEKLCEKGRREVWEMELDRLKNQDGEINR--NIMEETERAWKAEILSLESRKELLV 364
L+ E + E+ R ++ ++ ++ ++ R + E E + E R++ L
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 365 LKLEE------AEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSH 418
+ EE E+E E H + + ++ QE E R +++ ++ R+Q
Sbjct: 449 REQEERRDWLKREEETERHEQERRK-----QQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 419 IQLVR 423
Q +R
Sbjct: 504 EQQLR 508
Score = 50.1 bits (118), Expect = 7e-06
Identities = 50/225 (22%), Positives = 100/225 (44%), Gaps = 36/225 (16%)
Query: 188 QDDDQDSSSLKLSQNIAVQTDFKTADSE-VNTDQDIEKNLDKMMTERTLLKERYQEVLDK 246
+++++ LK Q ++ K + E + ++ E+ L + E +ER Q++L
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE----EERRQQLLKS 636
Query: 247 QRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQD 306
+ Q E + Q ++ Q+RRE+ +K +E + Q + + EE +++ E ++E Q +
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 307 LKAEIEKLCEKGRREVWEMELD------------RLKNQDGEINRNIMEETERAWKAEIL 354
+K+ I K W+ +L+ R + Q+G+ R EE R ++E+
Sbjct: 697 IKSRIPK---------WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Query: 355 SLESRKELLVLKLEE----------AEKEAELHLTYLKSTPPTLE 389
E + + EE AE+++E L + PP E
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
Score = 50.1 bits (118), Expect = 7e-06
Identities = 41/162 (25%), Positives = 87/162 (53%), Gaps = 13/162 (8%)
Query: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQ--RQVENQLQVQLKQLQQRREEEMKNHQEILK 277
Q E+ L + E+ L+ER ++ +++ +Q E QL + ++ ++R+E E + +E
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 278 AIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEI 337
++ + REE +K+ +E++ ++E++L+ E E+L + R + EL+R ++ E+
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 338 NRN----IMEETERAWKAEILSLESRKELLVLKLEEAEKEAE 375
+ + EE E+ + E L + R+E EE ++E E
Sbjct: 1147 QQEEEQLLREEPEKRRRQE-LERQYREE------EELQQEEE 1181
Score = 47.8 bits (112), Expect = 4e-05
Identities = 39/140 (27%), Positives = 73/140 (52%), Gaps = 10/140 (7%)
Query: 237 KERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE 296
+E+ +E+ + + Q E Q +++ + +QRR+EE+ ++ + ++ + E+ + E
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRD-RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHE 200
Query: 297 KKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSL 356
+EF +EQ + E+ +L KGR E + R + QD R EE E+ W+ L
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGRE---EKQQQRRERQD----RVFQEEEEKEWRKRETVL 253
Query: 357 ESRKELLVLKLEEAEKEAEL 376
RKE L+ EE +++ EL
Sbjct: 254 --RKEEEKLQEEEPQRQREL 271
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/157 (26%), Positives = 77/157 (49%), Gaps = 17/157 (10%)
Query: 238 ERYQEVLDKQRQVENQL--------QVQLKQLQQRREEEMKNHQEILKAIQDVTIKREET 289
ER D+ +Q E QL ++Q ++ Q R EEE++ +E L + T +R+E
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 290 KKKIEKEKKEFLQKEQDLKAEIEKLCEKGR------REVWEMELDRLKNQDGEINRNIME 343
+++ KE++ ++EQ L+ E EK + R E + E ++L ++ E R +
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR--Q 1134
Query: 344 ETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTY 380
E ER ++ E ++ +E L+ + E + EL Y
Sbjct: 1135 ELERQYREE-EEVQQEEEQLLREEPEKRRRQELERQY 1170
Score = 46.2 bits (108), Expect = 1e-04
Identities = 42/175 (24%), Positives = 90/175 (51%), Gaps = 9/175 (5%)
Query: 206 QTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRR 265
+ D K + E+ + K L++ +R +ER ++ L +++Q+ Q + Q QL+Q R
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEE--EQRLRRQERERKFLKEEQQLRCQEREQ--QLRQDR 1412
Query: 266 EEEMKNH-QEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWE 324
+ + + Q++ + +D + EE + + ++ +++FL++EQ L+ E + + + + E
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 325 MELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEE--AEKEAELH 377
E +L Q E +R +EE ++ + E +EL + E E+E +LH
Sbjct: 1473 REEQQLHRQ--ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/247 (19%), Positives = 106/247 (42%), Gaps = 25/247 (10%)
Query: 201 QNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQ 260
Q + D K + E + E+ L + +R +E Q L +Q + LQ + +
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ--LRRQERERKFLQEEQQL 1716
Query: 261 LQQRREEEMKNHQEILKAIQDVTIKREETKKKI--------EKEKKEFLQKEQDLKAEIE 312
+Q E + + +++ + + ++R+E +KI E+E+++ ++E+D K E
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 313 KLCEKGRRE--VWEMELDRLKNQDGEINRNIMEETER--------AWKAEILSLESRKEL 362
+ + R E + E DR ++ ++ + E+ R W+ E L LE +++
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Query: 363 LVLKLEEAEKEAELHLTYLKSTPPTL-----ETVRSKQEWETRLNGVRIMKKNVRDQFNS 417
L + + + E T KS E + +QE E +L I ++ +Q +
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896
Query: 418 HIQLVRN 424
+ +++
Sbjct: 1897 QVGEIKS 1903
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/190 (21%), Positives = 94/190 (49%), Gaps = 7/190 (3%)
Query: 228 KMMTERTLLKERYQEVLDKQRQVENQLQVQLK---QLQQRREEEMKNHQEILKAIQDVTI 284
++ E L++ ++ L ++RQ E Q Q +L+ QL++++EEE + QE + Q+
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 285 KREETK-KKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIME 343
++EE + +++ +E++E +++ + E E+ ++ RRE E ++ ++ ++ R
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 344 ETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNG 403
E+ + E + R+E + + ++ +E +L E K E E R
Sbjct: 390 RREQQLRRE---QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 404 VRIMKKNVRD 413
++ ++ RD
Sbjct: 447 LKREQEERRD 456
Score = 44.7 bits (104), Expect = 3e-04
Identities = 44/191 (23%), Positives = 93/191 (48%), Gaps = 22/191 (11%)
Query: 228 KMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKN--------HQEILKAI 279
K + LL+ER ++ L +Q + L+ + + +Q RE+++++ +++L+
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 280 QDVTIKREETKKKIEKE---------KKEFLQKEQDL-KAEIEKLCEKGRREVWEMELDR 329
++ ++R+E +K +E +++FLQ+EQ L + E+E+ + + E E ++
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 330 LKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEE--AEKEAELHLTYLKSTPPT 387
L+ Q E R I+EE + + E L ++ + EE ++ E L +S
Sbjct: 1740 LRRQ--ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Query: 388 LETVRSKQEWE 398
E + +QE E
Sbjct: 1798 REEEQLRQERE 1808
Score = 43.1 bits (100), Expect = 9e-04
Identities = 40/149 (26%), Positives = 79/149 (53%), Gaps = 13/149 (8%)
Query: 237 KERYQEVLDKQRQV----ENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKK 292
K QE L K++Q+ E +LQ + ++ ++R+E+E + +E ++ + REE +K+
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 293 IEKEKKEFLQKEQDLKAEIEKLC----EKGRREVWE---MELDRLKNQDGEINRNIMEET 345
+E++ +K++ L+ + E+L EK RR+ E E + L+ ++ ++ R E+
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 346 ER-AWKAEILSL-ESRKELLVLKLEEAEK 372
R W+ + E ++E L EE EK
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREK 1040
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/157 (21%), Positives = 83/157 (52%), Gaps = 7/157 (4%)
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDV 282
EK + + + +E ++ K+ V + + +L++ + +R+ E++ +E L+ ++
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 283 TIKREETKKKIEKEKKEFLQKEQDLKAEIE---KLCEKGRREVWEMELDRLKNQDGEINR 339
++RE ++ E+++++ L++EQ L+ + E + ++ RRE E + + ++ ++ R
Sbjct: 285 ELRRE---RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 340 NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAEL 376
E E+ + E E R++ L + EE +E +L
Sbjct: 342 EQEERREQQLRRE-QEEERREQQLRREQEEERREQQL 377
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/171 (21%), Positives = 82/171 (47%), Gaps = 14/171 (8%)
Query: 213 DSEVNTDQDIEKNLDKMMTE-----RTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREE 267
+ + ++ +++ ++++ E R +ER K +Q E QL + + ++R+E
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 268 EMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL 327
E K +E ++ + REE +K+ +E + +K+ +L+ E E+L + R + E
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 328 DRLKNQDGEINR---NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAE 375
+R ++ E+ + ++ E + + L + RKE EE ++E E
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE------EELQQEEE 1091
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/153 (20%), Positives = 78/153 (50%), Gaps = 8/153 (5%)
Query: 228 KMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKRE 287
K E+ LL+E +E ++RQ ++ + +QL Q REE+ QE + ++ ++ +
Sbjct: 1313 KSQEEKQLLREEREE--KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 288 ETKKKIEKEKKEFLQKEQD---LKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEE 344
E +K +E++ ++E++ LK E + C++ +++ + + + ++ +++R +E
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR---QE 1427
Query: 345 TERAWKAEILSLESRKELLVLKLEEAEKEAELH 377
+R ++ E + ++ EE + E H
Sbjct: 1428 RDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/155 (25%), Positives = 86/155 (55%), Gaps = 13/155 (8%)
Query: 227 DKMMTERTLL-KERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIK 285
D+ E+ L +E ++ L++++Q+ Q Q Q K LQ+ E++++ + + QD K
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQ-QRQRKFLQE--EQQLRRQERGQQRRQDRDRK 1556
Query: 286 -REETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMEL----DRLKNQDGEINRN 340
REE + + E+E+++ ++E+D K +E+ +K RR+ E + +L+ Q+G+ +
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEE--QKVRRQEQERKFMEDEQQLRRQEGQ--QQ 1612
Query: 341 IMEETERAWKAEILSLESRKELLVLKLEEAEKEAE 375
+ +E +R ++ + L+ R+E + + E K E
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/223 (21%), Positives = 100/223 (44%), Gaps = 35/223 (15%)
Query: 213 DSEVNTDQDIEKNLDK----MMTERTLLKE----RYQEVLDKQRQVENQLQVQLKQL--- 261
+ E Q++E+ K E LL+E R ++ ++Q + E +LQ + +QL
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 262 ------------QQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKA 309
Q R EEE++ +E L + +R+E +++ +E++ ++EQ L+
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 310 EIEKLCEKGRREV-WEMELDRLK--------NQDGEINRNIMEETERAWKAEILSLESRK 360
E EK ++ R+ E EL R K +Q ++ E E A + + + R+
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 361 ELLVLKLEEA---EKEAELHLTYLKSTPPTLETVRSKQEWETR 400
+LE++ +++++ L +L + + ++ W+ R
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Score = 39.7 bits (91), Expect = 0.010
Identities = 31/159 (19%), Positives = 82/159 (51%), Gaps = 5/159 (3%)
Query: 219 DQDIEKNLDKMMTER-TLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILK 277
D+ ++ +K +R T+L++ +++ +++ Q + +LQ + +QL++ +E++ ++ +
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 278 AIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEI 337
Q ++RE+ ++ ++E++ Q+E+ + E + E+ R + E + + Q
Sbjct: 295 Q-QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ--- 350
Query: 338 NRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAEL 376
R EE R + E R+E + + ++ +E +L
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Score = 39.7 bits (91), Expect = 0.010
Identities = 35/170 (20%), Positives = 81/170 (47%), Gaps = 16/170 (9%)
Query: 218 TDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILK 277
+ QD++ L + + R + D+ E QL+ + ++ +RR+ + + +++L+
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 278 AIQDVTIKREETKKKI--------EKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDR 329
++ +R+ET +K E+E++ ++E+D K E+L + + + E R
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR 1382
Query: 330 LKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLT 379
L+ Q+ E R ++E ++ L + R++ L + +E E L+
Sbjct: 1383 LRRQERE--RKFLKEEQQ------LRCQEREQQLRQDRDRKFREEEQQLS 1424
Score = 38.9 bits (89), Expect = 0.016
Identities = 25/130 (19%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 223 EKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDV 282
E+ L + +R +E Q ++++ E + + +QL+Q R + + +++L+ ++
Sbjct: 1420 EQQLSRQERDRKFREEEQQV---RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Query: 283 TIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIM 342
+ R+E +K +E+++ ++E+D K ++L + + E +L Q + R +
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ--RKFL 1534
Query: 343 EETERAWKAE 352
+E ++ + E
Sbjct: 1535 QEEQQLRRQE 1544
Score = 38.5 bits (88), Expect = 0.021
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 44/205 (21%)
Query: 223 EKNLDKMMTERTLLK-ERYQEVLD--------------KQRQVENQLQVQLKQLQQRR-- 265
EK L + E L + ER Q++ + ++++ + + + QL++ ++RR
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 266 --------EEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEK 317
+E+++ Q++L+ ++ ++REE +K+ +E++ ++E+ L+ E E+L +
Sbjct: 888 TLYAKPALQEQLRKEQQLLQE-EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 318 GRREVWEMELDRLKNQDGEINRN----IMEETERAWKAEILSLESRKELLVLKLEEAEKE 373
R + E +R +D ++ + + EE E+ + E +E + EE ++E
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE-------REKKYREEEELQQE 999
Query: 374 AELHLTYLKSTPPTLETVRSKQEWE 398
E L + R +QEWE
Sbjct: 1000 EEQLLREEREK-------RRRQEWE 1017
Score = 37.7 bits (86), Expect = 0.037
Identities = 29/125 (23%), Positives = 63/125 (50%), Gaps = 2/125 (1%)
Query: 228 KMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKRE 287
K E LL+ER ++ L +Q + L+ + + +Q R+ + + QE+ + E
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE-QELRSQEPERKFLEE 1520
Query: 288 ETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETER 347
E + ++ +++FLQ+EQ L+ + + R+ E ++L+ Q+ E + +E +R
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR-QEREEQQLSRQERDR 1579
Query: 348 AWKAE 352
++ E
Sbjct: 1580 KFRLE 1584
Score = 36.6 bits (83), Expect = 0.082
Identities = 47/201 (23%), Positives = 88/201 (43%), Gaps = 17/201 (8%)
Query: 208 DFKTADSEVNTDQDIEKNLDKMMTERTLLKE----RYQEVLDKQRQVENQLQVQ--LKQL 261
D K + E + E+ L + +R E R QE K + E QL+ Q +QL
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 262 QQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDL-KAEIEKLCEKGRR 320
+Q R+ + + +++L+ ++ + R+E +K FL++E L + E E+ R
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRK-------FLEEEPQLRRQEREQQLRHDRD 1666
Query: 321 EVWEMELDRLKNQDGEINRNIMEETERAWKAEILSL-ESRKELLVLKLEEAEKEAELHLT 379
+ E L Q+GE + +E +R ++ E L +E L+ E+ + EL
Sbjct: 1667 RKFREEEQLL--QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 380 YLKSTPPTLETVRSKQEWETR 400
+ + ET + + + R
Sbjct: 1725 FREEEQLRQETEQEQLRRQER 1745
Score = 36.2 bits (82), Expect = 0.11
Identities = 32/165 (19%), Positives = 74/165 (44%), Gaps = 8/165 (4%)
Query: 241 QEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF 300
+ +L +RQ E+Q + + + Q E + Q+ + +++ E+++K+ E+++
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDR 166
Query: 301 LQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGE-------INRNIMEETERAWKAEI 353
+++++L + ++ E+ R E +L K + E + R + E R + E
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 354 LSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWE 398
++ V + EE EKE T L+ L+ +++ E
Sbjct: 227 QQQRRERQDRVFQ-EEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Score = 35.8 bits (81), Expect = 0.14
Identities = 35/162 (21%), Positives = 84/162 (51%), Gaps = 9/162 (5%)
Query: 209 FKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEE 268
F+ + +V + K L++ E+ L +ER+++ ++++ ++ + + QL + Q+R +
Sbjct: 1432 FREEEQQVRRQERERKFLEE---EQQLRQERHRKFREEEQLLQEREEQQLHR-QERDRKF 1487
Query: 269 MKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDL-KAEIEKLCEKGRREVWEMEL 327
++ Q++ + +D RE+ + E E+K FL++EQ L + + ++ + +++ E
Sbjct: 1488 LEEEQQLRRQERDRKF-REQELRSQEPERK-FLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 328 DRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEE 369
+ + QD + R EE + + E L ++ +LEE
Sbjct: 1546 GQQRRQDRD--RKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Score = 33.5 bits (75), Expect = 0.69
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 12/162 (7%)
Query: 232 ERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVT--IKREET 289
ER ++R+ +++ Q Q + + K+LQ EEE +E + +Q+ ++ ++
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 290 KKKIEKEKKE---FLQKEQDLKAEIEKLCEK-GRREVWEMELDRLKNQDGEINRNIME-- 343
+++ ++++++ Q E++ K L K +E E L+ ++ E+ R E
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR 921
Query: 344 ---ETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLK 382
E ER ++ E L+ +E L+ + E + E Y K
Sbjct: 922 RRQEQERQYREE-EQLQQEEEQLLREEREKRRRQERERQYRK 962
Score = 32.0 bits (71), Expect = 2.0
Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 19/134 (14%)
Query: 251 ENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKK-EFLQKEQDL-- 307
+ + Q++ ++ QQR + + +E K + +++ E+EK+ +FL++E+ L
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEE----------KEQRRRQRREREKELQFLEEEEQLQR 842
Query: 308 --KAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETER----AWKAEILSLESRKE 361
+A+ + E G +E E + + +D + + EE +R + L + RKE
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902
Query: 362 LLVLKLEEAEKEAE 375
+L+ EE E + E
Sbjct: 903 QQLLQEEEEELQRE 916
Score = 31.6 bits (70), Expect = 2.6
Identities = 17/72 (23%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 237 KERYQEVLDKQRQVENQLQVQLKQLQQRRE----EEMKNHQEILKAIQDVTIKREETKKK 292
++R ++ D+Q + E Q Q K ++ +E EE K QE + +++ I+R++ +++
Sbjct: 1834 EQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Query: 293 IEKEKKEFLQKE 304
++ E +E
Sbjct: 1894 RHRQVGEIKSQE 1905
Score = 30.0 bits (66), Expect = 7.6
Identities = 37/165 (22%), Positives = 77/165 (46%), Gaps = 14/165 (8%)
Query: 239 RYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKK 298
++QE RQ + + Q + Q + EE+ + ++ L A + +RE + E++++
Sbjct: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR 806
Query: 299 E--FLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQD-----GEINRNIMEETERAWKA 351
E FL +E++ + + E+ + + E ++L+ ++ E + E+ ER
Sbjct: 807 EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQ 866
Query: 352 EILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQE 396
E + R + +LEE E++ H Y K P E +R +Q+
Sbjct: 867 E----QRRDQKWRWQLEE-ERKRRRHTLYAK--PALQEQLRKEQQ 904
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 52.4 bits (124), Expect = 1e-06
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 95/486 (19%)
Query: 64 NVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEGDTS 123
N+ E+S + G AG+ + +GE AL L+G L + + EE
Sbjct: 619 NLCAEYSRADGGPEAGELPS-----IGE--ATAALALAGRRPSRGLAGASGRSSEE---- 667
Query: 124 LRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEG 183
G T++L S E+S + ++ +E + S +P+ ++G
Sbjct: 668 -------------PGVATQRLWE---SMERSDEENLKEECSSTESTQQEHEDAPSTKLQG 711
Query: 184 VRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLL---KERY 240
+ ++++ +Q + K E+ +Q ++++ + ER LL +E
Sbjct: 712 EVLALEEER-------AQVLGHVEQLKVRVKEL--EQQLQESAREAEMERALLQGEREAE 762
Query: 241 QEVLDKQRQVENQLQVQLKQL----QQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE 296
+ +L K+++ +QLQ +L L Q+ R++E + + K +D+ ++ E + ++E+E
Sbjct: 763 RALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEE 822
Query: 297 KKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSL 356
++ Q KAE+ + K R+E L L +Q G+I ++E+ER + + SL
Sbjct: 823 RELAGQGLLRSKAELLRSIAK-RKE----RLAILDSQAGQIRAQAVQESERLARDKNASL 877
Query: 357 ESRKELLVLKLEEAEKEAELHLTY--LKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQ 414
+ L +E EK L Y L P +T + +E E L + ++
Sbjct: 878 Q-------LLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLL----LPAVDLEQW 926
Query: 415 FNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPM 474
+ + + G +S P + PP P++ LQV++ G+ T P+
Sbjct: 927 YQELMAGLGTGPAAAS----PHSSPPPLPAKASRQLQVYRSKMD---------GEATSPL 973
Query: 475 VMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPP 534
P S PLP S G +S V+ G P +++
Sbjct: 974 ---------------------PRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQ 1012
Query: 535 PGLGGV 540
G G +
Sbjct: 1013 NGTGSL 1018
Score = 33.1 bits (74), Expect = 0.90
Identities = 26/128 (20%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
Query: 188 QDDDQDSSSLKLSQNIAVQTDFKTADS--EVNTDQDIEKNLDKMMTERTLLKERYQEVLD 245
+ D +S+ N A D ++ S ++ +++EK L + E+ L E + ++
Sbjct: 1115 ESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREME 1174
Query: 246 KQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQ 305
+RQ + + + +Q+++R + E Q++++ ++V ++ ++ + + ++KE
Sbjct: 1175 LRRQALEEERRRREQVERRLQSESARRQQLVE--KEVKMREKQFSQARPLTRYLPIRKED 1232
Query: 306 -DLKAEIE 312
DLK IE
Sbjct: 1233 FDLKTHIE 1240
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 52.4 bits (124), Expect = 1e-06
Identities = 103/486 (21%), Positives = 196/486 (40%), Gaps = 95/486 (19%)
Query: 64 NVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEGDTS 123
N+ E+S + G AG+ + +GE AL L+G L + + EE
Sbjct: 619 NLCAEYSRADGGPEAGELPS-----IGE--ATAALALAGRRPSRGLAGASGRSSEE---- 667
Query: 124 LRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEG 183
G T++L S E+S + ++ +E + S +P+ ++G
Sbjct: 668 -------------PGVATQRLWE---SMERSDEENLKEECSSTESTQQEHEDAPSTKLQG 711
Query: 184 VRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLL---KERY 240
+ ++++ +Q + K E+ +Q ++++ + ER LL +E
Sbjct: 712 EVLALEEER-------AQVLGHVEQLKVRVKEL--EQQLQESAREAEMERALLQGEREAE 762
Query: 241 QEVLDKQRQVENQLQVQLKQL----QQRREEEMKNHQEILKAIQDVTIKREETKKKIEKE 296
+ +L K+++ +QLQ +L L Q+ R++E + + K +D+ ++ E + ++E+E
Sbjct: 763 RALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEE 822
Query: 297 KKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSL 356
++ Q KAE+ + K R+E L L +Q G+I ++E+ER + + SL
Sbjct: 823 RELAGQGLLRSKAELLRSIAK-RKE----RLAILDSQAGQIRAQAVQESERLARDKNASL 877
Query: 357 ESRKELLVLKLEEAEKEAELHLTY--LKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQ 414
+ L +E EK L Y L P +T + +E E L + ++
Sbjct: 878 Q-------LLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLL----LPAVDLEQW 926
Query: 415 FNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPM 474
+ + + G +S P + PP P++ LQV++ G+ T P+
Sbjct: 927 YQELMAGLGTGPAAAS----PHSSPPPLPAKASRQLQVYRSKMD---------GEATSPL 973
Query: 475 VMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPP 534
P S PLP S G +S V+ G P +++
Sbjct: 974 ---------------------PRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQ 1012
Query: 535 PGLGGV 540
G G +
Sbjct: 1013 NGTGSL 1018
Score = 33.1 bits (74), Expect = 0.90
Identities = 26/128 (20%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
Query: 188 QDDDQDSSSLKLSQNIAVQTDFKTADS--EVNTDQDIEKNLDKMMTERTLLKERYQEVLD 245
+ D +S+ N A D ++ S ++ +++EK L + E+ L E + ++
Sbjct: 1115 ESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREME 1174
Query: 246 KQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQ 305
+RQ + + + +Q+++R + E Q++++ ++V ++ ++ + + ++KE
Sbjct: 1175 LRRQALEEERRRREQVERRLQSESARRQQLVE--KEVKMREKQFSQARPLTRYLPIRKED 1232
Query: 306 -DLKAEIE 312
DLK IE
Sbjct: 1233 FDLKTHIE 1240
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 52.4 bits (124), Expect = 1e-06
Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 6/139 (4%)
Query: 432 PQIPTPTLPPPP---SETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPI 488
P +P + PPPP + + QV P+P P +P + P + + P S
Sbjct: 735 PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI-PAPTSTKT 793
Query: 489 LNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAETPR 548
+ P ++Q + P+ P + P + P P PP PPP L ++ P
Sbjct: 794 VAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV--PPPTLPKQQSFCAKPP 851
Query: 549 PQPVDKLEKILEKLLTRFP 567
P P+ + +++++ ++FP
Sbjct: 852 PSPLSPVPSVVKQIASQFP 870
Score = 39.3 bits (90), Expect = 0.013
Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 22/126 (17%)
Query: 429 SSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPI 488
SS+P +P+P PPPP E+ + PSP AP P P S P +
Sbjct: 907 SSIP-VPSPDFPPPPPESSLVFPPPPPSPVPAPPPP--PPPTASPTPDKSGSPGKKTSKT 963
Query: 489 LNPALSQP---SQPSSPLPGSHGR-----NSPGLGSLV----------SPHGPHMPPAAS 530
+P +P Q +S + S G P + SLV SP +PP A+
Sbjct: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA 1023
Query: 531 IPPPPG 536
PP PG
Sbjct: 1024 -PPKPG 1028
Score = 38.9 bits (89), Expect = 0.016
Identities = 36/137 (26%), Positives = 45/137 (32%), Gaps = 20/137 (14%)
Query: 432 PQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMP-----MVMPSADPRSLSF 486
P PTP +PP + F PSP P P + T+P P P S
Sbjct: 803 PPTPTPPVPPAKKQPAFPASYIPPSP---PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP 859
Query: 487 PILNPALSQ----------PSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAAS--IPPP 534
++ SQ SQP P+P + SP P P S PPP
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP 919
Query: 535 PGLGGVKASAETPRPQP 551
P + P P P
Sbjct: 920 PPESSLVFPPPPPSPVP 936
Score = 32.3 bits (72), Expect = 1.5
Identities = 36/120 (30%), Positives = 45/120 (37%), Gaps = 16/120 (13%)
Query: 435 PTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALS 494
P+P LPPPP P P P P + + P SA P + + + L
Sbjct: 624 PSPPLPPPPPPP-------PPPPPPPPPPPPPLPSQSAPSA-GSAAPMFVKYSTIT-RLQ 674
Query: 495 QPSQPSS-----PLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAETPRP 549
SQ S P P S LV P+G +PP PPPP G A + P P
Sbjct: 675 NASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV-VPPPPPPPPPPTPGSAMAQLK-PAP 732
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 52.4 bits (124), Expect = 1e-06
Identities = 75/311 (24%), Positives = 130/311 (41%), Gaps = 32/311 (10%)
Query: 74 PGSSAGDTSAAHQVVLGENL---IATALCLSGSGSQSDLKDVASTAGEEGDTSLRESLHP 130
PG G QV G + T + GSGS + AS EE + R +LH
Sbjct: 585 PGDEVGSEQRGEQVTNGREAGAELLTEVNRLGSGSSA-----ASEEEEEEEEPPRRTLH- 638
Query: 131 VTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVD--Q 188
+ R+ + C + A E+ L+E LD S A G RV Q
Sbjct: 639 LRRNRISNCSQRAGARPGSLPERKGPELCLEE------LDAAIPGSRAVGGSKARVQARQ 692
Query: 189 DDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQR 248
+S +L+Q Q + + +++ L + L ++ + + +
Sbjct: 693 VPPATASEWRLAQ---AQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELE 749
Query: 249 QVENQLQVQLKQLQ-QRREEEMKNHQEILKAIQDVTIKRE----ETKKKIEKEKKEFLQK 303
Q Q++ +L + Q Q RE E K Q+ + + +R +++ ++ KEKK+ ++
Sbjct: 750 QEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATER 809
Query: 304 EQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETE--RAWKAEILSLESRKE 361
L A+ EK R + E + ++ Q G++ R + EETE R +AE+ + R +
Sbjct: 810 LVSLSAQSEK-----RLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVK 864
Query: 362 LLVLKLEEAEK 372
L LK E+ +K
Sbjct: 865 ELELKHEQQQK 875
Score = 29.6 bits (65), Expect = 10.0
Identities = 44/184 (23%), Positives = 87/184 (47%), Gaps = 19/184 (10%)
Query: 198 KLSQNIAVQTDFKTA-DSEVNTDQDIEKNLD-KMMTERTLLKERYQEVLD---KQRQVEN 252
+L + + +T+ K ++E++ Q K L+ K ++ +LK + +E+ K+R N
Sbjct: 837 QLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSN 896
Query: 253 QLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIE 312
V L+Q Q+ E++ QE+ K +Q EE +++ K ++ L K++ L E
Sbjct: 897 GSVVSLEQQQKIEEQKKWLDQEMEKVLQQ-RRALEELGEELHK-REAILAKKEALMQEKT 954
Query: 313 KLCEKGRREVWEMELD------RLKNQDGEIN------RNIMEETERAWKAEILSLESRK 360
L K R + D RL++ + E++ R ++++ + EI SL K
Sbjct: 955 GLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEK 1014
Query: 361 ELLV 364
+ L+
Sbjct: 1015 DSLL 1018
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,280,332
Number of Sequences: 37866
Number of extensions: 1690645
Number of successful extensions: 20872
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 431
Number of HSP's successfully gapped in prelim test: 1704
Number of HSP's that attempted gapping in prelim test: 10875
Number of HSP's gapped (non-prelim): 7512
length of query: 703
length of database: 18,247,518
effective HSP length: 109
effective length of query: 594
effective length of database: 14,120,124
effective search space: 8387353656
effective search space used: 8387353656
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.