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Search of human proteins with 239741142
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]
(492 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens] 1015 0.0
gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens] 677 0.0
gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] 337 1e-92
gi|42519916 forkhead box O3A [Homo sapiens] 319 3e-87
gi|4503739 forkhead box O3A [Homo sapiens] 319 3e-87
gi|103472003 forkhead box O4 [Homo sapiens] 311 1e-84
gi|9257222 forkhead box O1 [Homo sapiens] 280 3e-75
gi|134142824 forkhead box D2 [Homo sapiens] 103 3e-22
gi|145309320 forkhead box Q1 [Homo sapiens] 98 2e-20
gi|119395716 forkhead box C1 [Homo sapiens] 96 1e-19
gi|12751477 forkhead box L2 [Homo sapiens] 94 3e-19
gi|24497501 forkhead box A1 [Homo sapiens] 93 5e-19
gi|4758392 forkhead box D1 [Homo sapiens] 92 1e-18
gi|21618325 forkhead box E1 [Homo sapiens] 91 2e-18
gi|6912372 forkhead box D3 [Homo sapiens] 91 3e-18
gi|195947376 forkhead box I2 [Homo sapiens] 90 5e-18
gi|11386197 forkhead box E3 [Homo sapiens] 89 9e-18
gi|4885237 forkhead box C2 [Homo sapiens] 88 2e-17
gi|22779860 forkhead box L1 [Homo sapiens] 86 6e-17
gi|50345831 forkhead box J3 [Homo sapiens] 84 3e-16
gi|32307177 forkhead box G1 [Homo sapiens] 81 2e-15
gi|21618327 forkhead box I1 isoform a [Homo sapiens] 79 7e-15
gi|208431824 forkhead box I3 [Homo sapiens] 78 2e-14
gi|24497504 forkhead box A2 isoform 2 [Homo sapiens] 77 3e-14
gi|194394143 forkhead box A2 isoform 1 [Homo sapiens] 77 3e-14
gi|24497506 forkhead box A3 [Homo sapiens] 77 5e-14
gi|4557595 forkhead box F2 [Homo sapiens] 76 6e-14
gi|28973785 forkhead box S1 [Homo sapiens] 76 6e-14
gi|60498992 forkhead box P4 isoform 3 [Homo sapiens] 76 6e-14
gi|29789367 forkhead box P4 isoform 2 [Homo sapiens] 76 6e-14
>gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]
Length = 492
Score = 1015 bits (2624), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60
MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT
Sbjct: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60
Query: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR
Sbjct: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
Query: 121 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 180
YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR
Sbjct: 121 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 180
Query: 181 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 240
RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD
Sbjct: 181 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 240
Query: 241 DYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPR 300
DYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPR
Sbjct: 241 DYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPR 300
Query: 301 LAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGK 360
LAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGK
Sbjct: 301 LAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGK 360
Query: 361 GAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA 420
GAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA
Sbjct: 361 GAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA 420
Query: 421 AAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLA 480
AAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLA
Sbjct: 421 AAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLA 480
Query: 481 GAPPPNQSWVPG 492
GAPPPNQSWVPG
Sbjct: 481 GAPPPNQSWVPG 492
>gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]
Length = 562
Score = 677 bits (1747), Expect = 0.0
Identities = 329/332 (99%), Positives = 329/332 (99%)
Query: 2 AAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA 61
AAKLRAH VDVDPDFAPQSRP S TWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA
Sbjct: 179 AAKLRAHHVDVDPDFAPQSRPHSSTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA 238
Query: 62 PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY 121
PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY
Sbjct: 239 PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY 298
Query: 122 VPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRRR 181
VPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRRR
Sbjct: 299 VPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRRR 358
Query: 182 AVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASDD 241
AVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASDD
Sbjct: 359 AVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASDD 418
Query: 242 YEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRL 301
YEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRL
Sbjct: 419 YEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRL 478
Query: 302 AELGGPLGLHGGGGAGLPEGLLDGAQDAYGPR 333
AELGGPLGLHGGGGAGLPEGLLDGAQDAYGPR
Sbjct: 479 AELGGPLGLHGGGGAGLPEGLLDGAQDAYGPR 510
Score = 114 bits (285), Expect = 2e-25
Identities = 93/223 (41%), Positives = 101/223 (45%), Gaps = 48/223 (21%)
Query: 275 SPLMYPSPASALSPALGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRP 334
+P P +S +PA PG +P A+ H A D Y
Sbjct: 383 APERSPDDSSPSAPA-----PGPVPAAAKWAASPASH--------------ASDDYEAWA 423
Query: 335 APRPG--PVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRS-ALAH--PISLMTLPGEAG 389
R G P+LG EL A A Y PA + S AL P L L G
Sbjct: 424 DFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRLAELGG 483
Query: 390 AAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFSGSLECD 449
GL H G P GLL A A GP A G+LECD
Sbjct: 484 PLGL----HGGGGAGLPEGLL------DGAQDAYGPRARA--------------GTLECD 519
Query: 450 VESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 492
VESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
Sbjct: 520 VESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 562
>gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]
Length = 589
Score = 337 bits (865), Expect = 1e-92
Identities = 163/170 (95%), Positives = 164/170 (96%)
Query: 323 LDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM 382
L+G Q P PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM
Sbjct: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM 479
Query: 383 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF 442
TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF
Sbjct: 480 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF 539
Query: 443 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 492
SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
Sbjct: 540 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589
Score = 289 bits (739), Expect = 5e-78
Identities = 138/138 (100%), Positives = 138/138 (100%)
Query: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60
MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT
Sbjct: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60
Query: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR
Sbjct: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
Query: 121 YVPYFKDKGDSNSSAGWK 138
YVPYFKDKGDSNSSAGWK
Sbjct: 121 YVPYFKDKGDSNSSAGWK 138
>gi|42519916 forkhead box O3A [Homo sapiens]
Length = 673
Score = 319 bits (818), Expect = 3e-87
Identities = 204/455 (44%), Positives = 252/455 (55%), Gaps = 93/455 (20%)
Query: 3 AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39
A L +V++DP+F PQSRPRSCTWPL +P+L DED
Sbjct: 9 APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68
Query: 40 G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65
G A+G G +A G +D G A ++
Sbjct: 69 GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128
Query: 66 -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119
P P GA G + K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188
Query: 120 RYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPR 179
R VPYFKDKGDSNSSAGWKNSIRHNLSLH+RF+RVQNEGTGKSSWW++NP+GGK+GK PR
Sbjct: 189 RCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPR 248
Query: 180 RRAVSMDNGAKFLRIKGKASKKK-QLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHA 238
RRAVSMDN K+ + +G+A+KKK LQ S DD SPS +KW SP S +
Sbjct: 249 RRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADD-SPS--------QLSKWPGSPTSRS 299
Query: 239 SDDYEAWADFRG---------GGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPA 289
SD+ +AW DFR GR L A E DE + AP SP++Y S AS LSP+
Sbjct: 300 SDELDAWTDFRSRTNSNASTVSGR-LSPIMASTELDEVQDDDAPLSPMLYSSSAS-LSPS 357
Query: 290 LGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELA 349
+ C ELPRL ++ G + L+ G L + LLD P +P P G L
Sbjct: 358 VSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNI-----TLPPSQPSPT----GGLM 408
Query: 350 LAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTL 384
++ Y KG+ +P + S + P SL +L
Sbjct: 409 QRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSL 443
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%)
Query: 410 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 467
L D+L G Y+ +A P+ ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN
Sbjct: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641
Query: 468 FDSALPPP------PPGLAGA-PPPNQSWVPG 492
FDS + GA +QSWVPG
Sbjct: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673
>gi|4503739 forkhead box O3A [Homo sapiens]
Length = 673
Score = 319 bits (818), Expect = 3e-87
Identities = 204/455 (44%), Positives = 252/455 (55%), Gaps = 93/455 (20%)
Query: 3 AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39
A L +V++DP+F PQSRPRSCTWPL +P+L DED
Sbjct: 9 APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68
Query: 40 G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65
G A+G G +A G +D G A ++
Sbjct: 69 GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128
Query: 66 -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119
P P GA G + K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188
Query: 120 RYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPR 179
R VPYFKDKGDSNSSAGWKNSIRHNLSLH+RF+RVQNEGTGKSSWW++NP+GGK+GK PR
Sbjct: 189 RCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPR 248
Query: 180 RRAVSMDNGAKFLRIKGKASKKK-QLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHA 238
RRAVSMDN K+ + +G+A+KKK LQ S DD SPS +KW SP S +
Sbjct: 249 RRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADD-SPS--------QLSKWPGSPTSRS 299
Query: 239 SDDYEAWADFRG---------GGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPA 289
SD+ +AW DFR GR L A E DE + AP SP++Y S AS LSP+
Sbjct: 300 SDELDAWTDFRSRTNSNASTVSGR-LSPIMASTELDEVQDDDAPLSPMLYSSSAS-LSPS 357
Query: 290 LGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELA 349
+ C ELPRL ++ G + L+ G L + LLD P +P P G L
Sbjct: 358 VSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNI-----TLPPSQPSPT----GGLM 408
Query: 350 LAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTL 384
++ Y KG+ +P + S + P SL +L
Sbjct: 409 QRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSL 443
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%)
Query: 410 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 467
L D+L G Y+ +A P+ ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN
Sbjct: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641
Query: 468 FDSALPPP------PPGLAGA-PPPNQSWVPG 492
FDS + GA +QSWVPG
Sbjct: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673
>gi|103472003 forkhead box O4 [Homo sapiens]
Length = 505
Score = 311 bits (796), Expect = 1e-84
Identities = 209/504 (41%), Positives = 263/504 (52%), Gaps = 61/504 (12%)
Query: 10 VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67
+D+DPDF PQSRPRSCTWPLP+P++A E + + E G P+ P
Sbjct: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75
Query: 68 PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
P LGA GP + SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR
Sbjct: 76 PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133
Query: 121 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 180
VPYFKDKGDSNSSAGWKNSIRHNLSLH++FI+V NE TGKSSWWMLNPEGGK+GK PRR
Sbjct: 134 TVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRR 193
Query: 181 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 240
RA SMD+ +K LR + KA KKK P P+ ++P++ PV AKW+ SP S +
Sbjct: 194 RAASMDSSSKLLRGRSKAPKKKPSVLP-APPEGATPTS----PVGHFAKWSGSPCSRNRE 248
Query: 241 DYEAWADFR----GGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPG 296
+ + W FR + + L + E LA P S A + P L
Sbjct: 249 EADMWTTFRPRSSSNASSVSTRLSPLRPES--EVLAEEIPASVSSYAGGVPPTLNEGL-- 304
Query: 297 EL---PRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRP-APRPGPVLGAPGELALAG 352
EL L L G G L + G Y +P GP+ G + +
Sbjct: 305 ELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCFSSSQ 364
Query: 353 AAAAYPGKGAAPYAPPA-----------------------PSRSALAHPISLMTLPGEA- 388
A A P PPA PS S LA + L P EA
Sbjct: 365 ALEALLTSDTPP--PPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAP 422
Query: 389 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGP--LGAAPDRFPADLDLDMFSGSL 446
G + L P + PP + +P P A+ DR P DLDLDM+ +L
Sbjct: 423 GPSSLVP---TLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENL 479
Query: 447 ECDVESIILNDFMDSDE-MDFNFD 469
ECD+++II +D MD E +DFNF+
Sbjct: 480 ECDMDNII-SDLMDEGEGLDFNFE 502
>gi|9257222 forkhead box O1 [Homo sapiens]
Length = 655
Score = 280 bits (715), Expect = 3e-75
Identities = 165/373 (44%), Positives = 200/373 (53%), Gaps = 87/373 (23%)
Query: 10 VDVDPDFAPQSRPRSCTWPLPQPDL----------------AGDEDGALGAGVAEGA--- 50
V++DPDF P RPRSCTWPLP+P+ A + D A G A A
Sbjct: 8 VEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAVS 67
Query: 51 -------------ED------------------------CGPERRATAPAMAPAPPLGAE 73
ED CG + A + PAPP
Sbjct: 68 ADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPP 127
Query: 74 VGPL------------------RKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIY 115
GPL RK+ SSRRNAWGNLSYADLITKAIES+ +KRLTLSQIY
Sbjct: 128 PGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIY 187
Query: 116 DWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTG 175
+WMV+ VPYFKDKGDSNSSAGWKNSIRHNLSLH++FIRVQNEGTGKSSWWMLNPEGGK+G
Sbjct: 188 EWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSG 247
Query: 176 KTPRRRAVSMDNGAKFLRIKGKASKKK-QLQAPERSPDDSSPSAPAPGPVPAAAKWAASP 234
K+PRRRA SMDN +KF + + +A+KKK LQ+ + DS P +KW ASP
Sbjct: 248 KSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDS--------PGSQFSKWPASP 299
Query: 235 ASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRC 294
SH++DD++ W+ F RP A + L S + P ++
Sbjct: 300 GSHSNDDFDNWSTF----RPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKM 355
Query: 295 PGELPRLAELGGP 307
LP L+E+ P
Sbjct: 356 ASTLPSLSEISNP 368
Score = 54.7 bits (130), Expect = 2e-07
Identities = 25/43 (58%), Positives = 32/43 (74%), Gaps = 1/43 (2%)
Query: 431 DRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALP 473
++ P+DLD MF L+CD+ESII ND MD D +DFNFD+ LP
Sbjct: 596 EKLPSDLD-GMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLP 637
Score = 32.0 bits (71), Expect = 1.3
Identities = 38/124 (30%), Positives = 43/124 (34%), Gaps = 25/124 (20%)
Query: 332 PRPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHPISLMT------- 383
P P P A A +G+AAA P A P A A + +SL+
Sbjct: 26 PLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAVSADFMSNLSLLEESEDFPQ 85
Query: 384 LPGE------AGAAGLAPPGHAAAFGGPPGGLLLDALP-----------GPYAAAAAGPL 426
PG A AA A G F GP G L A P P AAAGPL
Sbjct: 86 APGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPPPGPLSQHPPVPPAAAGPL 145
Query: 427 GAAP 430
P
Sbjct: 146 AGQP 149
>gi|134142824 forkhead box D2 [Homo sapiens]
Length = 495
Score = 103 bits (258), Expect = 3e-22
Identities = 134/434 (30%), Positives = 165/434 (38%), Gaps = 83/434 (19%)
Query: 31 QPDLAGDED-------------GALGAGVAEGAEDCGPERRATAPAMAPAPPLG--AEVG 75
+ DLA DE+ + GA A G+ G A P PP G A
Sbjct: 64 EADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRS 123
Query: 76 PLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSA 135
PL K SY LIT AI +P KRLTLS+I +++ PY+++K
Sbjct: 124 PLVKPP---------YSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREK-----FP 169
Query: 136 GWKNSIRHNLSLHTRFIRVQNE--GTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLR 193
W+NSIRHNLSL+ F+++ E GK ++W L+PE A DNG+ FLR
Sbjct: 170 AWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPES----------ADMFDNGS-FLR 218
Query: 194 IKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGR 253
+ K K++ L P P G A A P A Y A+ G
Sbjct: 219 -RRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAA---YGAYGYGYGLAL 274
Query: 254 PLLGEAAELEDDEALEALAPSSPLMYPSP---------ASALSPALGSRCPGELPRLAEL 304
P G P P +P P A+A +P S PG A
Sbjct: 275 PAYG-------------APPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGR--AAAPP 319
Query: 305 GGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAY--PGKGA 362
GP GAG + GP PA P LGA A A AA+ P G
Sbjct: 320 PGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPA-FLGAELGCAKAFYAASLSPPAAGT 378
Query: 363 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPP-------GHAAAFGGPPGGLLLDALP 415
A P A R L G AG AG P GH PPG + P
Sbjct: 379 AAGLPTALLRQGLKTDAGGGAGGGGAG-AGQRPSFSIDHIMGHGGGGAAPPGA--GEGSP 435
Query: 416 GPYAAAAAGPLGAA 429
GP AAAAGP G A
Sbjct: 436 GPPFAAAAGPGGQA 449
Score = 33.1 bits (74), Expect = 0.59
Identities = 33/99 (33%), Positives = 38/99 (38%), Gaps = 24/99 (24%)
Query: 332 PRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAA 391
P P P P P EL L G AAA GA + P + A +
Sbjct: 231 PHPHPHPHP------ELLLRGGAAAAGDPGA--FLPGFAAYGAYGY------------GY 270
Query: 392 GLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 430
GLA P A+G PP G P P+A A A AAP
Sbjct: 271 GLALP----AYGAPPPGPAPHPHPHPHAFAFAAAAAAAP 305
>gi|145309320 forkhead box Q1 [Homo sapiens]
Length = 403
Score = 97.8 bits (242), Expect = 2e-20
Identities = 116/385 (30%), Positives = 159/385 (41%), Gaps = 82/385 (21%)
Query: 39 DGALGAGVAEGAEDCGPERRATA------PAMAPAPPLG-AEVGPLRKAKSSRRNAWGNL 91
DG AG GAE+ P A A A A P G A G ++K R
Sbjct: 63 DGEQSAGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPY 122
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY LI AI + RLTL++I ++++ P+F+ S GW+NS+RHNLSL+ F
Sbjct: 123 SYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFR-----GSYTGWRNSVRHNLSLNDCF 177
Query: 152 IRVQNEGT---GKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPE 208
++V + + GK ++WMLNP T +G F R + + S + + AP
Sbjct: 178 VKVLRDPSRPWGKDNYWMLNPNSEYT----------FADGV-FRRRRKRLSHRAPVPAPG 226
Query: 209 RSPDDSS--PSAPAPGPV---------PAAAKWAASPASHASDDYEAWADFRGGGRPLLG 257
P+++ P+AP P P PA + ASPA S + + R R
Sbjct: 227 LRPEEAPGLPAAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFR---- 282
Query: 258 EAAELEDDEALEALAPSSPLMY---PSPASALSPAL--GSRCPGELPRLAELGGPLGLHG 312
L AP + L + P P PAL + C LP A
Sbjct: 283 -------SRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAY--------- 326
Query: 313 GGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSR 372
GAG P L GA++A P AP P+L AP L AA A P +G A
Sbjct: 327 --GAGEPARL--GAREAEVPPTAP---PLLLAP----LPAAAPAKPLRGPA--------- 366
Query: 373 SALAHPISLMTLPGEAGAAGLAPPG 397
+ AH + LP AA + PG
Sbjct: 367 AGGAHLYCPLRLPAALQAASVRRPG 391
>gi|119395716 forkhead box C1 [Homo sapiens]
Length = 553
Score = 95.5 bits (236), Expect = 1e-19
Identities = 113/415 (27%), Positives = 162/415 (39%), Gaps = 81/415 (19%)
Query: 32 PDLAGDEDGALGAGVAEGAEDCGPERRATAPAMAPAPPLGAE---------VGPLRKAKS 82
P L G++ A A G G AP + P AE GP
Sbjct: 17 PYLGGEQSYYRAAAAAAG----GGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQ 72
Query: 83 SRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIR 142
+ SY LIT AI++APDK++TL+ IY +++ P+++D + GW+NSIR
Sbjct: 73 PKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRD-----NKQGWQNSIR 127
Query: 143 HNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASK 200
HNLSL+ F++V ++ GK S+W L+P+ + +M FLR + + K
Sbjct: 128 HNLSLNECFVKVPRDDKKPGKGSYWTLDPD-----------SYNMFENGSFLRRRRRFKK 176
Query: 201 KKQLQAPERSPDDSSPSAPAPG--PVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGE 258
K ++ E P PG P PA + A A D +
Sbjct: 177 KDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSP 236
Query: 259 AAELEDDEAL-EALAPSSPLMYPSPASALSPALGSRCPGELPRLAELGGPLGLHGGGGAG 317
L AL A + P + +S+ S + GS PG LP L
Sbjct: 237 PQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLS------------ 284
Query: 318 LPEGLLDGAQDAYGPRPAPRPGP---------------VLGAPGELAL---AGAAAAYPG 359
LDGA D+ P PAP P + G+P A +G A+
Sbjct: 285 -----LDGA-DSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAA 338
Query: 360 KGAAPYAPP------APSRSAL-AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPG 407
A APP +P +S+L + P S + G +G G G A A GG G
Sbjct: 339 SSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGG----GGAGAAGGAGG 389
>gi|12751477 forkhead box L2 [Homo sapiens]
Length = 376
Score = 94.0 bits (232), Expect = 3e-19
Identities = 102/340 (30%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY LI AI + +KRLTLS IY +++ P+++ + GW+NSIRHNLSL+ F
Sbjct: 58 SYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYE-----KNKKGWQNSIRHNLSLNECF 112
Query: 152 IRVQNEGTG--KSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPER 209
I+V EG G K ++W L+P + + KG ++++++ P R
Sbjct: 113 IKVPREGGGERKGNYWTLDP------------------ACEDMFEKGNYRRRRRMKRPFR 154
Query: 210 SPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGG-GRPLLGEAAELEDDEAL 268
P P+ PG A AA A A AD G P ++ L + L
Sbjct: 155 PP----PAHFQPGKGLFGAGGAAGGCGVAG----AGADGYGYLAPPKYLQSGFLNNSWPL 206
Query: 269 EALAPSSPLMYPSPASALSPALGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQD 328
P SP+ Y S A + A + A GP G A + +GL
Sbjct: 207 P--QPPSPMPYASCQMAAAAAAAAAA-------AAAAGP---GSPGAAAVVKGLAG---- 250
Query: 329 AYGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 388
PA GP G +Y G G P APP P HP A
Sbjct: 251 -----PAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPH---PHPHPHAHHLHAA 302
Query: 389 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGA 428
A APP H AA PP G L A P A A P A
Sbjct: 303 AAPPPAPPHHGAA--APPPGQLSPASPATAAPPAPAPTSA 340
>gi|24497501 forkhead box A1 [Homo sapiens]
Length = 472
Score = 93.2 bits (230), Expect = 5e-19
Identities = 84/274 (30%), Positives = 119/274 (43%), Gaps = 35/274 (12%)
Query: 40 GALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPLRKA--------KSSRRNAWGNL 91
GA+GA A GP A P M+P + +G R K S +A
Sbjct: 114 GAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPY 173
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY LIT AI+ AP K LTLS+IY W++ PY++ + W+NSIRH+LS + F
Sbjct: 174 SYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYR-----QNQQRWQNSIRHSLSFNDCF 228
Query: 152 IRVQN--EGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPER 209
++V + GK S+W L+P+ G +NG +LR + + +KQ A
Sbjct: 229 VKVARSPDKPGKGSYWTLHPDSGN----------MFENGC-YLRRQKRFKCEKQPGAGGG 277
Query: 210 SPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRG-----GGRPLLGEAAELED 264
S S GP ++ S AS+ S D G G P G AA +
Sbjct: 278 GGSGSGGSGAKGGP---ESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQT 334
Query: 265 DEALEALAPSSPLMYPSPASALSPALGSRCPGEL 298
+ A A +PAS+ +P + S PG L
Sbjct: 335 LDHSGATATGGASELKTPASSTAPPISSG-PGAL 367
Score = 33.1 bits (74), Expect = 0.59
Identities = 40/123 (32%), Positives = 47/123 (38%), Gaps = 28/123 (22%)
Query: 305 GGPLGLHGGGGAGLPEGLLD--GAQDAYGPRP--------------APRPGPVLGAPGEL 348
GG G G G G PE D GA + P AP PGP +P L
Sbjct: 277 GGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPA-ASPQTL 335
Query: 349 ALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS-----LMTLPGEAGAAGLAPPGHAAAFG 403
+GA A GA+ PA S+ A PIS L ++P A GLAP
Sbjct: 336 DHSGATAT---GGASELKTPA---SSTAPPISSGPGALASVPASHPAHGLAPHESQLHLK 389
Query: 404 GPP 406
G P
Sbjct: 390 GDP 392
>gi|4758392 forkhead box D1 [Homo sapiens]
Length = 465
Score = 92.0 bits (227), Expect = 1e-18
Identities = 103/345 (29%), Positives = 139/345 (40%), Gaps = 59/345 (17%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY LIT AI +P KRLTLS+I +++ PY+++K W+NSIRHNLSL+ F
Sbjct: 129 SYIALITMAILQSPKKRLTLSEICEFISGRFPYYREK-----FPAWQNSIRHNLSLNDCF 183
Query: 152 IRVQNE--GTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPER 209
+++ E GK ++W L+PE A DNG+ FLR + K K++ L P
Sbjct: 184 VKIPREPGNPGKGNYWTLDPES----------ADMFDNGS-FLR-RRKRFKRQPLLPPNA 231
Query: 210 SPDDS------SPSAPAPGPVPAAAKW--AASPASHASDDYEAWADFRGGGRPLLGEAAE 261
+ +S + A P AAA + A P HA Y + G P +
Sbjct: 232 AAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAY-GYGPYGCGYGLQLPPYAPPSA 290
Query: 262 LEDDEALEALA----PSSPLMYPSPASALSP-----------ALGSRCPGELPRLAELGG 306
L A A A P SP P P A + LG+ PG LP A G
Sbjct: 291 LFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAG 350
Query: 307 PLGLHG------------GGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAA 354
G GG G AQ A + +P P PV P + G
Sbjct: 351 GPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSSGGGC 410
Query: 355 AAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHA 399
AA G A A +RS +A + + + A G G A
Sbjct: 411 AAQAAVGPA----AALTRSLVAAAAAAASSVSSSAALGTLHQGTA 451
Score = 36.6 bits (83), Expect = 0.053
Identities = 52/163 (31%), Positives = 57/163 (34%), Gaps = 34/163 (20%)
Query: 298 LPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGP-VLG------------- 343
LP A L L G G AG G D A A PAP P P G
Sbjct: 227 LPPNAAAAESLLLRGAGAAG---GAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLP 283
Query: 344 --APGELALAGAAAAYPGKGAAPYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPG 397
AP A AAAA P++PP P +A + P GAA P
Sbjct: 284 PYAPPSALFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLP 343
Query: 398 HAAAFGGPPGGLLLDALP-----------GPYAAAAAGPLGAA 429
+AA G PG L P GP AAAAA AA
Sbjct: 344 ASAAKAGGPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAA 386
>gi|21618325 forkhead box E1 [Homo sapiens]
Length = 373
Score = 91.3 bits (225), Expect = 2e-18
Identities = 123/428 (28%), Positives = 158/428 (36%), Gaps = 88/428 (20%)
Query: 28 PLPQPDLAG---DEDG--ALGAGVAEGAEDCGPE-RRATAPAMAPAPPLGAEVGPLRKAK 81
P PQP++ +E G A GAGV A G RR P PP
Sbjct: 8 PPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPY----------- 56
Query: 82 SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSI 141
SY LI AI AP++RLTL IY ++ P+++D + W+NSI
Sbjct: 57 ----------SYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRD-----NPKKWQNSI 101
Query: 142 RHNLSLHTRFIRVQNEG--TGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKAS 199
RHNL+L+ F+++ E GK ++W L+P A M FLR + K
Sbjct: 102 RHNLTLNDCFLKIPREAGRPGKGNYWALDP-----------NAEDMFESGSFLR-RRKRF 149
Query: 200 KKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEA 259
K+ L D++ +A A AAA A Y A + G P
Sbjct: 150 KRSDLSTYPAYMHDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPG-AVYAGYAPP----- 203
Query: 260 AELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRLAELG----GPLGLHGGGG 315
+LA P+ Y PA++ P E P ELG GP G
Sbjct: 204 ----------SLAAPPPVYY--PAASPGPCRVFGLVPERPLSPELGPAPSGPGGSCAFAS 251
Query: 316 AGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYP-GKGAAPYAPPAPSRSA 374
AG P Y P P + A AG AYP G G+A +A +
Sbjct: 252 AGAP-----ATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFA----AAGR 302
Query: 375 LAHPISLMTLPGEAGAA-------GLAPPGHAAAFGG--PPGGLLLDALPGPYAAAAAGP 425
LA P S G +G G PG A G PGG L A G Y A A
Sbjct: 303 LAGPAS-PPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAAA 361
Query: 426 LGAAPDRF 433
DRF
Sbjct: 362 YPGGIDRF 369
>gi|6912372 forkhead box D3 [Homo sapiens]
Length = 478
Score = 90.5 bits (223), Expect = 3e-18
Identities = 122/430 (28%), Positives = 172/430 (40%), Gaps = 88/430 (20%)
Query: 34 LAGDEDGALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSY 93
+ G+E GA G G G+ G +AP+ P + V P SY
Sbjct: 108 VGGEEGGASGGGPGAGSGSAG--------GLAPSKPKNSLVKP-------------PYSY 146
Query: 94 ADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIR 153
LIT AI +P K+LTLS I +++ PY+++K W+NSIRHNLSL+ F++
Sbjct: 147 IALITMAILQSPQKKLTLSGICEFISNRFPYYREK-----FPAWQNSIRHNLSLNDCFVK 201
Query: 154 VQNE--GTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPE--- 208
+ E GK ++W L+P+ DNG+ FLR + + + +Q E
Sbjct: 202 IPREPGNPGKGNYWTLDPQSED----------MFDNGS-FLRRRKRFKRHQQEHLREQTA 250
Query: 209 ---RSPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDD 265
+S S +A A P + PA+ A A AA L+
Sbjct: 251 LMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAG------AYSHPAAAAAAAAAAALQYP 304
Query: 266 EALEALA----PSSPLMYPSPASALSPALGSRC-PGELPRLAELGGPLGLHG-GGGAGLP 319
AL +A P+ PL+ + A GS+ PG +L LG G G AG
Sbjct: 305 YALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTT 364
Query: 320 EGLLDGAQDAYGPRPAPRPGPVLG----APGELAL-AGAAAAYPGKGAAPYA-----PPA 369
L+ A RP+ ++G APG A+ AG A G G A PP
Sbjct: 365 ASLIKSEPSA---RPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRPPG 421
Query: 370 PSRSALA----HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGP 425
+SA P+SL A +AP P G L P A+AAA
Sbjct: 422 TVQSAALMATHQPLSL-----SRTTATIAP-----ILSVPLSGQFLQ----PAASAAAAA 467
Query: 426 LGAAPDRFPA 435
AA ++PA
Sbjct: 468 AAAAQAKWPA 477
>gi|195947376 forkhead box I2 [Homo sapiens]
Length = 318
Score = 89.7 bits (221), Expect = 5e-18
Identities = 86/274 (31%), Positives = 119/274 (43%), Gaps = 50/274 (18%)
Query: 11 DVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAG--VAEGAEDCGPERRATAPAMAP-- 66
D+ P AP + ++ P P + GA+G G + A P+ A+ P AP
Sbjct: 7 DLGPSSAPPGQAQATAHP---PGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPY 63
Query: 67 -APPLGAEVGPLRKAKSSRRNA---WGNLS--------------YADLITKAIESAPDKR 108
AP GA GPL A A W +LS Y+ LI AI+SAP ++
Sbjct: 64 AAPSYGAP-GPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRK 122
Query: 109 LTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWM 166
LTLSQIY ++ P++K S AGW+NSIRHNLSL+ F +V + GK ++W
Sbjct: 123 LTLSQIYQYVAGNFPFYK-----RSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWT 177
Query: 167 LNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPG---P 223
L+P K DNG + K ++ + A RS S A AP P
Sbjct: 178 LDPNCEK----------MFDNG----NFRRKRKRRAEASAAVRSGARSVGGAEAPALEPP 223
Query: 224 VPAAAKWAASPASHASDDYEAWADFRGGGRPLLG 257
A ASP+ A + ++ F L G
Sbjct: 224 SAACLDLQASPSPSAPEAATCFSGFASAMSALAG 257
Score = 32.3 bits (72), Expect = 1.0
Identities = 25/58 (43%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 306 GPLGLHGGGGA-GLPEGLLDGAQDAYGPRPAP--------RPGPVLGAPGELALAGAA 354
G LG GGG + L A GP PAP PGP+LGAPG LA A A
Sbjct: 30 GDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLA 87
>gi|11386197 forkhead box E3 [Homo sapiens]
Length = 319
Score = 89.0 bits (219), Expect = 9e-18
Identities = 116/391 (29%), Positives = 155/391 (39%), Gaps = 102/391 (26%)
Query: 7 AHQVDVDPDFAPQSRPR----SCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATAP 62
A + D+DP A P + + P P P LAG E G A G + P
Sbjct: 2 AGRSDMDPPAAFSGFPALPAVAPSGPPPSP-LAGAEPGREPEEAAAGRGEAAP------- 53
Query: 63 AMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYV 122
PAP GP R+ + + SY LI A+ AP +RLTL+ IY ++
Sbjct: 54 --TPAP------GPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERF 105
Query: 123 PYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNE--GTGKSSWWMLNPEGGKTGKTPRR 180
+++D S W+NSIRHNL+L+ F++V E GK ++W L+P
Sbjct: 106 AFYRD-----SPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAA--------- 151
Query: 181 RAVSMDNGAKFLRIKGKASKKKQLQAPERS------PDDSSPSAPAPGPV-----PAAAK 229
A DNG+ FLR + K K+ +L A + P +P APAPGP P+A
Sbjct: 152 -ADMFDNGS-FLR-RRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAGP 208
Query: 230 WAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEALAP-SSPLMYPSPASALSP 288
+ PA S D L E A L E AP ++ +P A+A SP
Sbjct: 209 GPSPPARLFSVDSLV---------NLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASP 259
Query: 289 ALGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGP-VLGAPGE 347
L S+ P L PA RPGP L A
Sbjct: 260 PLYSQVPDRL---------------------------------VLPATRPGPGPLPAEPL 286
Query: 348 LALAGAAAAYPGKGAAPYAPPAPSRSALAHP 378
LALAG AAA P +P + L P
Sbjct: 287 LALAGPAAA--------LGPLSPGEAYLRQP 309
>gi|4885237 forkhead box C2 [Homo sapiens]
Length = 501
Score = 87.8 bits (216), Expect = 2e-17
Identities = 107/367 (29%), Positives = 155/367 (42%), Gaps = 59/367 (16%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY LIT AI++AP+K++TL+ IY +++ P++++ + GW+NSIRHNLSL+ F
Sbjct: 76 SYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRE-----NKQGWQNSIRHNLSLNECF 130
Query: 152 IRV--QNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPER 209
++V ++ GK S+W L+P+ + +M FLR + + KK + E
Sbjct: 131 VKVPRDDKKPGKGSYWTLDPD-----------SYNMFENGSFLRRRRRFKKKDVSKEKEE 179
Query: 210 SPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALE 269
P A PA A +P A ++ P++ + L + AL+
Sbjct: 180 RAHLKEPPPAASKGAPATPHLADAP-KEAEKKVVIKSEAASPALPVITKVETLSPESALQ 238
Query: 270 ALAPSSPLMYP--SPASALSPALGSRCPGELP----------RLAELGGPLGLHGGGGAG 317
+P S P SP +L P + P LP R + GG L G G AG
Sbjct: 239 G-SPRSAASTPAGSPDGSL-PEHHAAAPNGLPGFSVENIMTLRTSPPGGELS-PGAGRAG 295
Query: 318 L---PEGLLDGAQD--AYGPRPAPRPGPVLGAPGELALAGAAAAYPG--KGAAPYAPPAP 370
L P L A AYG +P + A G A + Y G + A PPA
Sbjct: 296 LVVPPLALPYAAAPPAAYG-QPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPAL 354
Query: 371 SRSALAH------PISLMTL-PGEAGAAGLAPPGHAAAFGG--------PPGGLLLDALP 415
+ H P+S + L G+ GA LA GH G PP P
Sbjct: 355 DEALSDHPSGPTSPLSALNLAAGQEGA--LAATGHHHQHHGHHHPQAPPPPPAPQPQPTP 412
Query: 416 GPYAAAA 422
P AAAA
Sbjct: 413 QPGAAAA 419
>gi|22779860 forkhead box L1 [Homo sapiens]
Length = 345
Score = 86.3 bits (212), Expect = 6e-17
Identities = 77/258 (29%), Positives = 110/258 (42%), Gaps = 50/258 (19%)
Query: 54 GPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQ 113
GPER A APA L A +A++ ++ + SY LI AI+ AP++R+TL+
Sbjct: 22 GPERPGLPLAFAPAAALAAS----GRAETPQKPPY---SYIALIAMAIQDAPEQRVTLNG 74
Query: 114 IYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNE--GTGKSSWWMLNPE- 170
IY +++ P++ D + GW+NSIRHNLSL+ F++V E GK S+W L+P
Sbjct: 75 IYQFIMDRFPFYHD-----NRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRC 129
Query: 171 --------------------GGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPERS 210
G K PR A+ G + + +
Sbjct: 130 LDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAA 189
Query: 211 PDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEA 270
P SP P P PA W + AS + +A +G +G+AA D
Sbjct: 190 PAGPSPLLDGPSP-PAPLHWPGT----ASPNEDAGDAAQGAAAVAVGQAARTGD------ 238
Query: 271 LAPSSPLMYPSPASALSP 288
P SPL PAS SP
Sbjct: 239 -GPGSPL---RPASRSSP 252
>gi|50345831 forkhead box J3 [Homo sapiens]
Length = 622
Score = 84.0 bits (206), Expect = 3e-16
Identities = 44/102 (43%), Positives = 65/102 (63%), Gaps = 9/102 (8%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SYA LIT AI S+P K++TLS+IY W+ PY+++ G +GWKNSIRHNLSL+ F
Sbjct: 82 SYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAG-----SGWKNSIRHNLSLNKCF 136
Query: 152 IRV--QNEGTGKSSWWML--NPEGGKTGKTPRRRAVSMDNGA 189
++V + GK S+W + NP+ P++RA S++ +
Sbjct: 137 LKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERAS 178
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 80.9 bits (198), Expect = 2e-15
Identities = 60/181 (33%), Positives = 83/181 (45%), Gaps = 30/181 (16%)
Query: 28 PLPQPDLAGDEDGALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNA 87
P P P A DGA G+ G + G AP GA G K +
Sbjct: 106 PPPPPPPAAALDGAKADGLG-GKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGK 164
Query: 88 WGN----------------LSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDS 131
G SY LI AI +P+KRLTL+ IY+++++ PY+++
Sbjct: 165 DGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRE---- 220
Query: 132 NSSAGWKNSIRHNLSLHTRFIRVQN--EGTGKSSWWMLNPE------GGKTGKTPRRRAV 183
+ GW+NSIRHNLSL+ F++V + GK ++WML+P GG TGK RR
Sbjct: 221 -NKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTT 279
Query: 184 S 184
S
Sbjct: 280 S 280
>gi|21618327 forkhead box I1 isoform a [Homo sapiens]
Length = 378
Score = 79.3 bits (194), Expect = 7e-15
Identities = 55/153 (35%), Positives = 75/153 (49%), Gaps = 15/153 (9%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY+ LI AI APDKRLTLSQIY ++ P++ + S AGW+NSIRHNLSL+ F
Sbjct: 127 SYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFY-----NKSKAGWQNSIRHNLSLNDCF 181
Query: 152 IRV--QNEGTGKSSWWMLNPEGGK---TGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQA 206
+V + GK ++W L+P K G R+R D + + A +K +
Sbjct: 182 KKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASL---ALEKTESSL 238
Query: 207 PERSPDDSSPSAPAPGPVPAAAKWAASPASHAS 239
P SP + P G P +SP S
Sbjct: 239 PVDSPKTTEPQDILDGASPGGT--TSSPEKRPS 269
>gi|208431824 forkhead box I3 [Homo sapiens]
Length = 420
Score = 78.2 bits (191), Expect = 2e-14
Identities = 71/236 (30%), Positives = 104/236 (44%), Gaps = 34/236 (14%)
Query: 18 PQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPL 77
P P + P QP A G A+ A APA AP E+G L
Sbjct: 81 PPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAP--------AAPASPAAPAGPGELGWL 132
Query: 78 RKAKSS--RRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSA 135
A + SY+ LI AI+SAP+++LTLS IY ++ P+++ S A
Sbjct: 133 SMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQ-----RSKA 187
Query: 136 GWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGK-----TGKTPRRRAVSMDNG 188
GW+NSIRHNLSL+ F +V + GK ++W L+P K + R+R NG
Sbjct: 188 GWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASNG 247
Query: 189 AKFLRIKGKASKKKQLQAPERS-----PDDSSPS-----APAPGPVPAAAKWAASP 234
+ G + ++ L + S P++ SPS + +P P A+SP
Sbjct: 248 STV--AAGTSKSEEGLSSGLGSGVGGKPEEESPSTLLRPSHSPEPPEGTKSTASSP 301
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/101 (34%), Positives = 38/101 (37%), Gaps = 16/101 (15%)
Query: 330 YGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAG 389
Y P P APG A A A Y G A YA P +A A+P + PG G
Sbjct: 12 YSQPGLPPPAATAAAPG--APPAARAPY---GLADYAAPP---AAAANPYLWLNGPGVGG 63
Query: 390 AAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 430
A AA G PP P P AAAGP P
Sbjct: 64 PPSAAAAAAAAYLGAPP--------PPPPPGAAAGPFLQPP 96
Score = 37.4 bits (85), Expect = 0.031
Identities = 50/168 (29%), Positives = 62/168 (36%), Gaps = 25/168 (14%)
Query: 274 SSPLMYPSPASALSPAL--GSRCPGEL-----PRLAELGGPLGLHGGGGAGLPEGLLDGA 326
S P + P A+A +P +R P L P A L L+G G G P A
Sbjct: 13 SQPGLPPPAATAAAPGAPPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSAAAAAA 72
Query: 327 QDAYG-PRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSAL-AHPISLMTL 384
G P P P PG A G AA G P+A PAP+ A A P
Sbjct: 73 AAYLGAPPPPPPPG---AAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAPAG---- 125
Query: 385 PGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 432
PGE G +A PP Y+A A + +AP+R
Sbjct: 126 PGELGWLSMASREDLMKMVRPPYS---------YSALIAMAIQSAPER 164
>gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]
Length = 457
Score = 77.4 bits (189), Expect = 3e-14
Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 64/309 (20%)
Query: 32 PDLAGDEDGA---LGAGVAEGAEDCGPERRATAPAMAP---------------------A 67
P LAG GA G G + GA +P+++P +
Sbjct: 75 PSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANMNSMS 134
Query: 68 PPLG-AEVGPLRKAKSSRRN---AWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVP 123
P G A + R K+ RR+ A SY LIT AI+ +P+K LTLS+IY W++ P
Sbjct: 135 PMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFP 194
Query: 124 YFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQN--EGTGKSSWWMLNPEGGKTGKTPRRR 181
+++ + W+NSIRH+LS + F++V + GK S+W L+P+ G
Sbjct: 195 FYR-----QNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGN-------- 241
Query: 182 AVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKW--AASPASHAS 239
+NG +LR + + +KQL E + S A G + A+ AA PAS
Sbjct: 242 --MFENGC-YLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASET- 297
Query: 240 DDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELP 299
P E+ E + +PA+ALSP + PG+
Sbjct: 298 --------------PAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQ 343
Query: 300 R-LAELGGP 307
+ A L GP
Sbjct: 344 QAAAHLLGP 352
>gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]
Length = 463
Score = 77.4 bits (189), Expect = 3e-14
Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 64/309 (20%)
Query: 32 PDLAGDEDGA---LGAGVAEGAEDCGPERRATAPAMAP---------------------A 67
P LAG GA G G + GA +P+++P +
Sbjct: 81 PSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANMNSMS 140
Query: 68 PPLG-AEVGPLRKAKSSRRN---AWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVP 123
P G A + R K+ RR+ A SY LIT AI+ +P+K LTLS+IY W++ P
Sbjct: 141 PMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFP 200
Query: 124 YFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQN--EGTGKSSWWMLNPEGGKTGKTPRRR 181
+++ + W+NSIRH+LS + F++V + GK S+W L+P+ G
Sbjct: 201 FYR-----QNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGN-------- 247
Query: 182 AVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKW--AASPASHAS 239
+NG +LR + + +KQL E + S A G + A+ AA PAS
Sbjct: 248 --MFENGC-YLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASET- 303
Query: 240 DDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELP 299
P E+ E + +PA+ALSP + PG+
Sbjct: 304 --------------PAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQ 349
Query: 300 R-LAELGGP 307
+ A L GP
Sbjct: 350 QAAAHLLGP 358
>gi|24497506 forkhead box A3 [Homo sapiens]
Length = 350
Score = 76.6 bits (187), Expect = 5e-14
Identities = 76/251 (30%), Positives = 97/251 (38%), Gaps = 52/251 (20%)
Query: 16 FAPQSRPRSCTWPLPQPDLAGDEDGAL------GAGVAEGAEDCGPERRATAPAMAPAPP 69
+ P P S PLP LA A G GV+ G+ G P
Sbjct: 50 YPPGGLPAS---PLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMP 106
Query: 70 LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKG 129
G PL AK SY LIT AI+ AP K LTLS+IY W++ PY+++
Sbjct: 107 KGYR-RPLAHAKPP-------YSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE-- 156
Query: 130 DSNSSAGWKNSIRHNLSLHTRFIRVQN--EGTGKSSWWMLNPEGG--------------- 172
+ W+NSIRH+LS + F++V + GK S+W L+P G
Sbjct: 157 ---NQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRF 213
Query: 173 ----KTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAP---GPVP 225
K K A + NG G A+ A SP P AP P G
Sbjct: 214 KLEEKVKKGGSGAATTTRNGT------GSAASTTTPAATVTSPPQPPPPAPEPEAQGGED 267
Query: 226 AAAKWAASPAS 236
A SPAS
Sbjct: 268 VGALDCGSPAS 278
>gi|4557595 forkhead box F2 [Homo sapiens]
Length = 444
Score = 76.3 bits (186), Expect = 6e-14
Identities = 92/329 (27%), Positives = 124/329 (37%), Gaps = 70/329 (21%)
Query: 71 GAEVGPLRKAKSS-RRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKG 129
GA G +KA S RR SY LI AI+S+P KRLTLS+IY ++ P+F+
Sbjct: 82 GAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFR--- 138
Query: 130 DSNSSAGWKNSIRHNLSLHTRFIRVQN--EGTGKSSWWMLNP------EGGKTGKTPR-- 179
+ GWKNS+RHNLSL+ FI++ GK +W ++P E G + PR
Sbjct: 139 --GAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGF 196
Query: 180 RRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHAS 239
RR + G L P AP P+ ++
Sbjct: 197 RRKCQALKPMYHRVVSGLGFGASLL------PQGFDFQAPPSAPLGCHSQGGYGGLDMMP 250
Query: 240 DDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELP 299
Y+A G G P P M P+P GS P
Sbjct: 251 AGYDA-----GAGAPSHAHPHHHHHHHV--------PHMSPNP--------GSTYMASCP 289
Query: 300 RLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGA------ 353
A GG +G GGGG G YGP + P P A+A A
Sbjct: 290 VPAGPGG-VGAAGGGGGG-----------DYGPDSSSSP-----VPSSPAMASAIECHSP 332
Query: 354 ----AAAYPGKGAAPYAPPAPSRSALAHP 378
AA + GA+PY P+ + ++P
Sbjct: 333 YTSPAAHWSSPGASPYLKQPPALTPSSNP 361
>gi|28973785 forkhead box S1 [Homo sapiens]
Length = 330
Score = 76.3 bits (186), Expect = 6e-14
Identities = 94/329 (28%), Positives = 127/329 (38%), Gaps = 70/329 (21%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
SY LI AI+S+P +R TLS IY +++ +++ ++ GW+NSIRHNLSL+ F
Sbjct: 22 SYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYR-----HNRPGWQNSIRHNLSLNECF 76
Query: 152 IRVQNEG--TGKSSWWMLNPEGGKTGK----TPRRRAVSMDNGAKFLRIKGKASKKKQLQ 205
++V + GK S+W L+P+ + RRR + GA+ R KA ++ L+
Sbjct: 77 VKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKA-RRGPLR 135
Query: 206 APERSPD----------DSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPL 255
A + P P P P + A PAS + GRP
Sbjct: 136 ATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTD--------GRP- 186
Query: 256 LGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRLAELGGPLGLHGGGG 315
P M P S PA CPGELP
Sbjct: 187 -------------------RPPMEPKEISTPKPA----CPGELPVATSSSSCPAF----- 218
Query: 316 AGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGEL---ALAGAAAAYPG-----KGAAPY-A 366
G P G + P P P +G+ + AL A PG AAP A
Sbjct: 219 -GFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPA 277
Query: 367 PPAPSRSALAHPISLMTLPGEAGAAGLAP 395
PP P S L P+ L T E AG P
Sbjct: 278 PPTPPGS-LRAPLPLPTDHKEPWVAGGFP 305
>gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]
Length = 678
Score = 76.3 bits (186), Expect = 6e-14
Identities = 66/227 (29%), Positives = 100/227 (44%), Gaps = 41/227 (18%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
+YA LI +AI PD++LTL++IY+W R YF+ ++A WKN++RHNLSLH F
Sbjct: 469 TYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFR-----RNTATWKNAVRHNLSLHKCF 523
Query: 152 IRVQNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLR--IKGKASKKKQLQAPER 209
+RV+N K + W ++ + +RR M ++ I G +
Sbjct: 524 VRVENV---KGAVWTVDER-----EYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAA 575
Query: 210 SPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWAD---FRGGGRP------------ 254
+ S P +PG + + + P SH DD A + G P
Sbjct: 576 LAESSFPLLNSPGMLNPGSASSLLPLSH--DDVGAPVEPLPSNGSSSPPRLSPPQYSHQV 633
Query: 255 -LLGEAAELEDDEALEALAPSSPLMYPSPASALSPA---LGSRCPGE 297
+ E AE E+D P PL P+P+++ P L PGE
Sbjct: 634 QVKEEPAEAEEDR-----QPGPPLGAPNPSASGPPEDRDLEEELPGE 675
>gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]
Length = 667
Score = 76.3 bits (186), Expect = 6e-14
Identities = 66/227 (29%), Positives = 100/227 (44%), Gaps = 41/227 (18%)
Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRF 151
+YA LI +AI PD++LTL++IY+W R YF+ ++A WKN++RHNLSLH F
Sbjct: 458 TYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFR-----RNTATWKNAVRHNLSLHKCF 512
Query: 152 IRVQNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLR--IKGKASKKKQLQAPER 209
+RV+N K + W ++ + +RR M ++ I G +
Sbjct: 513 VRVENV---KGAVWTVDER-----EYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAA 564
Query: 210 SPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWAD---FRGGGRP------------ 254
+ S P +PG + + + P SH DD A + G P
Sbjct: 565 LAESSFPLLNSPGMLNPGSASSLLPLSH--DDVGAPVEPLPSNGSSSPPRLSPPQYSHQV 622
Query: 255 -LLGEAAELEDDEALEALAPSSPLMYPSPASALSPA---LGSRCPGE 297
+ E AE E+D P PL P+P+++ P L PGE
Sbjct: 623 QVKEEPAEAEEDR-----QPGPPLGAPNPSASGPPEDRDLEEELPGE 664
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.134 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,111,986
Number of Sequences: 37866
Number of extensions: 1826129
Number of successful extensions: 15818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 221
Number of HSP's successfully gapped in prelim test: 983
Number of HSP's that attempted gapping in prelim test: 10202
Number of HSP's gapped (non-prelim): 5141
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.