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Search of human proteins with 239508938
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239508938 PREDICTED: similar to hCG2036731 [Homo sapiens]
(503 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169171663 PREDICTED: similar to hCG2036731 [Homo sapiens] 1017 0.0
gi|239508938 PREDICTED: similar to hCG2036731 [Homo sapiens] 1017 0.0
gi|169171173 PREDICTED: similar to hCG2036731 [Homo sapiens] 1017 0.0
gi|239749177 PREDICTED: similar to hCG2036731 [Homo sapiens] 984 0.0
gi|203097724 cadherin-like 29 [Homo sapiens] 92 1e-18
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 86 8e-17
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 85 2e-16
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 85 2e-16
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 83 7e-16
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 82 1e-15
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 79 7e-15
gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens] 78 2e-14
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 78 2e-14
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 77 3e-14
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 73 7e-13
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 73 7e-13
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 73 7e-13
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 72 1e-12
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 72 1e-12
gi|40255133 hypothetical protein LOC222256 [Homo sapiens] 72 1e-12
gi|47059046 dachsous 2 isoform 1 [Homo sapiens] 72 2e-12
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 72 2e-12
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 72 2e-12
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 70 3e-12
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 70 4e-12
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 70 4e-12
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 70 4e-12
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 70 4e-12
gi|16507964 cadherin-like 23 isoform 2 precursor [Homo sapiens] 70 4e-12
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 69 8e-12
>gi|169171663 PREDICTED: similar to hCG2036731 [Homo sapiens]
Length = 503
Score = 1017 bits (2630), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL
Sbjct: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
Query: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF
Sbjct: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
Query: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC
Sbjct: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
Query: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF
Sbjct: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
Query: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT
Sbjct: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
Query: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA
Sbjct: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
Query: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK
Sbjct: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
Query: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA
Sbjct: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
Query: 481 LKKEILGNTSVTPGNNKAHTVKP 503
LKKEILGNTSVTPGNNKAHTVKP
Sbjct: 481 LKKEILGNTSVTPGNNKAHTVKP 503
>gi|239508938 PREDICTED: similar to hCG2036731 [Homo sapiens]
Length = 503
Score = 1017 bits (2630), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL
Sbjct: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
Query: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF
Sbjct: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
Query: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC
Sbjct: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
Query: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF
Sbjct: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
Query: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT
Sbjct: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
Query: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA
Sbjct: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
Query: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK
Sbjct: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
Query: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA
Sbjct: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
Query: 481 LKKEILGNTSVTPGNNKAHTVKP 503
LKKEILGNTSVTPGNNKAHTVKP
Sbjct: 481 LKKEILGNTSVTPGNNKAHTVKP 503
>gi|169171173 PREDICTED: similar to hCG2036731 [Homo sapiens]
Length = 503
Score = 1017 bits (2629), Expect = 0.0
Identities = 502/503 (99%), Positives = 503/503 (100%)
Query: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL
Sbjct: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
Query: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF
Sbjct: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
Query: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC
Sbjct: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
Query: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF
Sbjct: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
Query: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT
Sbjct: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
Query: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
+VGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA
Sbjct: 301 IVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
Query: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK
Sbjct: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
Query: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA
Sbjct: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
Query: 481 LKKEILGNTSVTPGNNKAHTVKP 503
LKKEILGNTSVTPGNNKAHTVKP
Sbjct: 481 LKKEILGNTSVTPGNNKAHTVKP 503
>gi|239749177 PREDICTED: similar to hCG2036731 [Homo sapiens]
Length = 564
Score = 984 bits (2543), Expect = 0.0
Identities = 487/487 (100%), Positives = 487/487 (100%)
Query: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL
Sbjct: 1 MSMGSKLKCEHDTNGKVEPHAADNHFQGAGLGPNQIMAGSGVITATKIFNYETDPIRFLL 60
Query: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF
Sbjct: 61 IVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVF 120
Query: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC
Sbjct: 121 ANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFC 180
Query: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF
Sbjct: 181 LDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF 240
Query: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT
Sbjct: 241 STGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYT 300
Query: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA
Sbjct: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
Query: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK
Sbjct: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
Query: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA
Sbjct: 421 KRLEKMSLSSYYFKKCFTDVIRADNHNNDYFPSVTNITRANQVSRPKGLDWYQGKSRVDA 480
Query: 481 LKKEILG 487
LKKEILG
Sbjct: 481 LKKEILG 487
>gi|203097724 cadherin-like 29 [Homo sapiens]
Length = 788
Score = 91.7 bits (226), Expect = 1e-18
Identities = 62/177 (35%), Positives = 91/177 (51%), Gaps = 12/177 (6%)
Query: 247 ITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNL 306
+ V+V V+ INE +P + + TF V E++ TL+G V TD D+P +N+EY GG
Sbjct: 429 VPVLVMVTPINEFSP--ACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYYTSGG-- 484
Query: 307 GTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISV 366
P F ++ +G + LL L+ E + Y++ V V D D P+ SG+ +TI V
Sbjct: 485 --PTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPN--HHLSGSCTITIEV 540
Query: 367 LNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEH----LSYSIVGEQDESR 419
++ND P C PP E IY+ + S PQE SYSIVG ++R
Sbjct: 541 EDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNR 597
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 85.9 bits (211), Expect = 8e-17
Identities = 94/341 (27%), Positives = 157/341 (46%), Gaps = 56/341 (16%)
Query: 88 DPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVG----GDHCAR-PFPLDSI 142
DP+ AT +D + S+ V A D + ++ R+N+ DH + P+ S
Sbjct: 1790 DPESGDLIATRRLDRERRSKYSLL-VRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSF 1848
Query: 143 NVTEKKSVGEIIARVKATDRDE----DSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
++ E G ++A + ATD D + + I + + +F L+P TG L + L+ +
Sbjct: 1849 DIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV 1908
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
+ Y L A D G F+T I V + +N+
Sbjct: 1909 ---QQYYILTVRAEDGGGQ----------------------FTT----IRVYFNILDVND 1939
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGG-NLGTPPKFYIEP 316
PI S ++++ S+ EN PV + V TDAD N+ + Y++ G +LG +F ++
Sbjct: 1940 NPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLG---QFTVDK 1996
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVC 376
+ GV+K+L +L+RE +S Y + V+V DL P + + TAQV+I +L++ND PP
Sbjct: 1997 N-GVLKVLKALDRESQSFYNLVVQVHDLPQ----IPASRFTSTAQVSIILLDVNDNPPTF 2051
Query: 377 NPPHL----ETQIYSTVESFHSAQLFSKDS-PQEHLSYSIV 412
P L E TV AQ DS P ++ Y+++
Sbjct: 2052 LSPKLTYIPENTPIDTV--VFKAQATDPDSGPNSYIEYTLL 2090
Score = 77.8 bits (190), Expect = 2e-14
Identities = 71/245 (28%), Positives = 117/245 (47%), Gaps = 46/245 (18%)
Query: 139 LDSINVTEKKSVGEIIARVKATDRDE--DSSIIYSFKTQQK-MFCLDPFTGTITLLQPLN 195
++S+NV E G I + KA D DE + ++YS K K +F ++ GTI+LL PL+
Sbjct: 897 IESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLD 956
Query: 196 LDNPSNSKIYSLETEATDNG--NNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
+ S Y +E A+D G +SS TV+V +V
Sbjct: 957 VHAGS----YQIEILASDMGVPQLSSSVILTVYVHDV----------------------- 989
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKF 312
N+ +P+ ++ ++ E+ PV++ KV +D D N + YT+ GN G F
Sbjct: 990 ---NDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTG--DAF 1044
Query: 313 YIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDE 372
I PD G + + L+RE++ +Y + V + +D +PL S T VT+ + ++ND
Sbjct: 1045 GIFPD-GQLYIKSELDRELQDRYVLMV----VASDRAVEPL---SATVNVTVILEDVNDN 1096
Query: 373 PPVCN 377
P+ N
Sbjct: 1097 RPLFN 1101
Score = 73.9 bits (180), Expect = 3e-13
Identities = 79/310 (25%), Positives = 129/310 (41%), Gaps = 49/310 (15%)
Query: 134 ARPFPLDSINVTEKKSVGEI--IARVKATDRDEDSSIIYSFK----TQQKMFCLDPFTGT 187
A F D T +S + + RV A+D DE ++ + + +++ F +D +G
Sbjct: 1207 APKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQ 1266
Query: 188 ITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAII 247
+TL+ L+ + + YSL +A D+G + T T+ ++ +D+
Sbjct: 1267 VTLIGKLDYEA---TPAYSLVIQAVDSGTIPLNSTCTLNIDILDE--------------- 1308
Query: 248 TVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVG-GN 305
N+ P S V EN + LV VT TD+D N ++ Y++ G N
Sbjct: 1309 ---------NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNN 1359
Query: 306 LGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTIS 365
GT F I P+TG I L L+ E +S YK+ +T D P RS T V I
Sbjct: 1360 HGT---FSISPNTGSIFLAKKLDFETQSLYKL--NITAKDQGRPP-----RSSTMSVVIH 1409
Query: 366 VLNMNDEPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQE----HLSYSIVGEQDESRKK 421
V + ND PP P + I + S + P LSY+I+ +
Sbjct: 1410 VRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHF 1469
Query: 422 RLEKMSLSSY 431
++++ + Y
Sbjct: 1470 TIDEVKGTIY 1479
Score = 67.0 bits (162), Expect = 4e-11
Identities = 65/239 (27%), Positives = 103/239 (43%), Gaps = 37/239 (15%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFK--TQQKMFCLDPFTGTITLLQPLNLD 197
++V E +GE+++ V ATD D +++ + YS F + P TG+I L + L+ +
Sbjct: 1322 VDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFE 1381
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
S +Y L A D G S T +V + +V D PSF G +++
Sbjct: 1382 TQS---LYKLNITAKDQGRPPRSSTMSVVI-HVRDFNDNPPSFPPGDIFKSIV------- 1430
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIEP 316
EN P+ T V VT D D N + YT++ + F I+
Sbjct: 1431 ----------------ENIPIGTSVISVTAHDPDADINGQLSYTIIQ-QMPRGNHFTIDE 1473
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
G I ++RE + +++ VK D A+P R R VTI V ++ND P+
Sbjct: 1474 VKGTIYTNAEIDREFANLFELTVKAND---QAVPIETR-RYALKNVTILVTDLNDNVPM 1528
Score = 65.1 bits (157), Expect = 1e-10
Identities = 60/240 (25%), Positives = 108/240 (45%), Gaps = 43/240 (17%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFK---TQQKMFCLDPFTGTITLLQPLNL 196
++V E G + ++ATD D ++ ++ +S + T ++ F LDP +G ++ + L+
Sbjct: 590 VSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDR 649
Query: 197 DNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
+ + YSL ATD G+ S + V +D I
Sbjct: 650 EEQA---FYSLLVLATDLGSPPQSSMARINVSLLD------------------------I 682
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIE 315
N+ +P+ + + EN P + + V+ TD D N ++Y++ G+ +F +
Sbjct: 683 NDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRS---RFQVN 739
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
+GVI +L+RE ++ Y++ + TD N Q A VTI+VL+ D PPV
Sbjct: 740 AQSGVISTRMALDREEKTAYQLQIVATDGGN-------LQSPNQAIVTITVLDTQDNPPV 792
Score = 64.7 bits (156), Expect = 2e-10
Identities = 87/383 (22%), Positives = 155/383 (40%), Gaps = 66/383 (17%)
Query: 40 SGVITATKIFNYETDPIRFLLI--VDTGRLYRHV-LTINIIDVPESPNCTADPKFSSGTA 96
+GV T++ +YE L + D G + + + NI+DV ++P P FS +
Sbjct: 1895 TGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNP-----PIFSLNSY 1949
Query: 97 TLEIDEDYPLFQSI--YRVTATDEVFANGDRLNVGGDHCARPFPLDSINVT--------E 146
+ + E+ P+ ++ + VT D+ + ++ F +D V E
Sbjct: 1950 STSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRE 2009
Query: 147 KKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYS 206
+S ++ +V D + + ++ Q + LD T L P P N+ I +
Sbjct: 2010 SQSFYNLVVQVH--DLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDT 2067
Query: 207 L--ETEATDNGNNTSSYTFTVFVENVDDPISC---------------------------- 236
+ + +ATD + +SY + + + S
Sbjct: 2068 VVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVAT 2127
Query: 237 ---DPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWP 293
PS S+ V+V V IN+ NPI + + + + EN+ T + +V D D
Sbjct: 2128 DKGQPSLSSSTE---VVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
Query: 294 FNN-MEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDP 352
N + Y +V GN T +F I+ TG I + L+RE Y + V+ TD +
Sbjct: 2185 TNGQVRYGIVNGN--TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGS------ 2236
Query: 353 LRQRSGTAQVTISVLNMNDEPPV 375
R+ T+ V+I +L++ND PV
Sbjct: 2237 -TPRTDTSTVSIVLLDINDFVPV 2258
Score = 63.9 bits (154), Expect = 3e-10
Identities = 104/398 (26%), Positives = 166/398 (41%), Gaps = 87/398 (21%)
Query: 89 PKFSSGTAT----LEIDEDYPLF-QSIYRV-------TATD--EVFA-NGD-------RL 126
P SS T L+I+++ P+F Q++Y+V T TD +VFA +GD R
Sbjct: 2132 PSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRY 2191
Query: 127 NVGGDHCARPFPLDSINVT-------EKKSVGEIIARVKATDRDED--------SSIIYS 171
+ + + F +DS+ +++ V+ATDR S ++
Sbjct: 2192 GIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLD 2251
Query: 172 FKTQQKMFCLDPFT-------GTI--TLLQPLNLDNP--SNSKIYSLETEATDNGNNTSS 220
+F L P++ GT+ T+LQ + D+ SNSK+ + GN ++
Sbjct: 2252 INDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKL----SYVLFGGNEDNA 2307
Query: 221 YTFTV-----------------FVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIG 263
+T + FV + S P+ TG I VIV +N+ P
Sbjct: 2308 FTLSASGELGVTQSLDRETKERFVLMITATDSGSPAL-TGTGTINVIV--DDVNDNVPTF 2364
Query: 264 SASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKL 323
++ A+ ++ E++P T V V +DAD N ++GGN +F I P TG I
Sbjct: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDAD-ASKNAVIRIIGGN----SQFTINPSTGQIIT 2419
Query: 324 LDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLET 383
L+RE + Y + V +D + P+PL S + V ++V ++ND PP T
Sbjct: 2420 SALLDRETKDNYTLVVVCSDAGS---PEPL---SSSTSVLVTVTDVNDNPPRFQHHPYVT 2473
Query: 384 QIYSTV--ESFHSAQLFSKD--SPQEHLSYSIVGEQDE 417
I S SF A + P L YS+ G E
Sbjct: 2474 HIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSE 2511
Score = 62.0 bits (149), Expect = 1e-09
Identities = 68/258 (26%), Positives = 117/258 (45%), Gaps = 41/258 (15%)
Query: 135 RPFPLDS--INVTEKKSVGEIIARVKATDRDEDS-----SIIYSFKTQQKMFCLDPFTGT 187
R FP S +V E VG ++A + TD D + S+ +Q+ F
Sbjct: 356 RYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF-------- 407
Query: 188 ITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGA--A 245
+Q + N S K+ S A D SY TV +V D P + A +
Sbjct: 408 --EVQSSKVPNLSLIKVAS----ALDR-ERIPSYNLTV---SVSDNYGAPPGAAVQARSS 457
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGG 304
+ ++++ V+ IN+ P+ S + ++ E +P + V ++ TD D N N+ Y++V G
Sbjct: 458 VASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSG 517
Query: 305 N-LGTPPKFYIEPDTGVIKLLDS--LNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQ 361
N LG F+I +G++ S L+RE+ SQ + + D + + AQ
Sbjct: 518 NGLGW---FHISEHSGLVTTGSSGGLDRELASQIVLNISARD-------QGVHPKVSYAQ 567
Query: 362 VTISVLNMNDEPPVCNPP 379
+ +++L++NDE PV + P
Sbjct: 568 LVVTLLDVNDEKPVFSQP 585
Score = 60.8 bits (146), Expect = 3e-09
Identities = 66/284 (23%), Positives = 120/284 (42%), Gaps = 49/284 (17%)
Query: 137 FPLDSINVTEKKSVGE--IIARVKATDRDEDSSIIYSF---KTQQKMFCLDPFTGTITLL 191
FP D +++T ++++G+ I ++ A D DE ++ + ++ F +DP +G L+
Sbjct: 1740 FPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG--DLI 1797
Query: 192 QPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIV 251
LD SK YSL A D+G +S + + +
Sbjct: 1798 ATRRLDRERRSK-YSLLVRA-DDGLQSSD--------------------------MRINI 1829
Query: 252 RVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPK 311
VS +N+ P S ++F + E++ +LV + TD D N E T +
Sbjct: 1830 TVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNG-EITYIVNEDDEDGI 1888
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F++ P TGV L L+ E++ Y + V+ D + T +V ++L++ND
Sbjct: 1889 FFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGG---------QFTTIRVYFNILDVND 1939
Query: 372 EPPVCNPPHLETQIYSTVESFHSAQLF----SKDSPQEHLSYSI 411
PP+ + T + + + +F + D L+YSI
Sbjct: 1940 NPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSI 1983
Score = 58.2 bits (139), Expect = 2e-08
Identities = 80/356 (22%), Positives = 132/356 (37%), Gaps = 88/356 (24%)
Query: 36 IMAGSGVITATKIFNYETDPIRFLLIVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGT 95
I + +G++T K +YE +H +TI+ ID A + S T
Sbjct: 3139 INSSTGILTLAKALDYEL-------------CQKHEMTISAID----GGWVARTGYCSVT 3181
Query: 96 AT-LEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEII 154
++++++ P+F S D+ F V E G +
Sbjct: 3182 VNVIDVNDNSPVFLS-------DDYFPT---------------------VLENAPSGTTV 3213
Query: 155 ARVKATDRDEDSSIIYSFKTQQK---MFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEA 211
+ ATD D ++ + ++ Q +F +DP TG IT T+
Sbjct: 3214 IHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVIT-------------------TQG 3254
Query: 212 TDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFS 271
+ SY TV NV D C + TV +++ NE P + + F
Sbjct: 3255 FLDFETKQSYHLTVKAFNVPDEERC--------SFATVNIQLKGTNEYVPRFVSKLYYFE 3306
Query: 272 VFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREI 331
+ E +P T+VG+V +D D + + ++ GN F I TG I + L+RE
Sbjct: 3307 ISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGN-SRKKGFQINKKTGQIYVSGILDREK 3365
Query: 332 ESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYS 387
E + + V + + D V ++VL+ ND PP IYS
Sbjct: 3366 EERVSLKVLAKNFGSIRGAD-----IDEVTVNVTVLDAND------PPIFTLNIYS 3410
Score = 57.4 bits (137), Expect = 3e-08
Identities = 61/239 (25%), Positives = 101/239 (42%), Gaps = 42/239 (17%)
Query: 141 SINVTEKKSVGEIIARVKATDRDE--DSSIIYSFKT--QQKMFCLDPFTGTITLLQPLNL 196
S + E S+G I+ V A DRD + I YS + ++ +F ++ TG +TL + L+
Sbjct: 3095 SATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDY 3154
Query: 197 DNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
+ + + + A D G + +V V V +
Sbjct: 3155 E---LCQKHEMTISAIDGG------------------------WVARTGYCSVTVNVIDV 3187
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIE 315
N+ +P+ + + +V EN+P T V + TDAD N + YTV + F I+
Sbjct: 3188 NDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSD---SDLFVID 3244
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
P+TGVI L+ E + Y + VK + +PD +R A V I + N+ P
Sbjct: 3245 PNTGVITTQGFLDFETKQSYHLTVKAFN-----VPD--EERCSFATVNIQLKGTNEYVP 3296
Score = 55.8 bits (133), Expect = 9e-08
Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 37/242 (15%)
Query: 142 INVTEKKSVGEIIARVKATDRDE--DSSIIYSFKTQQKM--FCLDPFTGTITLLQPLNLD 197
+N++E+ G ++ + ATD D ++++ YS + + F + +G +T LD
Sbjct: 482 VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLD 541
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
S+I L A D G + P S ++T++ +N
Sbjct: 542 RELASQIV-LNISARDQGVH--------------------PKVSYAQLVVTLL----DVN 576
Query: 258 ELNPIGSA-SAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEP 316
+ P+ S + SV EN+P T + + TD D N + F ++P
Sbjct: 577 DEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDP 636
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVC 376
+G + + SL+RE ++ Y + V TDL + +S A++ +S+L++ND PV
Sbjct: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSP-------PQSSMARINVSLLDINDNSPVF 689
Query: 377 NP 378
P
Sbjct: 690 YP 691
Score = 52.4 bits (124), Expect = 1e-06
Identities = 60/238 (25%), Positives = 98/238 (41%), Gaps = 41/238 (17%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSS-----IIYSFKTQQKMFCLDPFTGTITLLQPLN 195
S+ ++E +G + V A D D S + F ++P TG IT+ L+
Sbjct: 3410 SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELD 3469
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSR 255
+ IY+L A D+G PS +TG+A +++V +
Sbjct: 3470 RET---LPIYNLSVLAVDSGT---------------------PS-ATGSA--SLLVTLED 3502
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIE 315
IN+ P+ + S V EN TLV + TD D P N +T + G ++
Sbjct: 3503 INDNGPMLTVSEG--EVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSL 3560
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
GV+ ++RE + + ++V D +P Q S T V I+V++ ND P
Sbjct: 3561 STAGVLSTTREIDREQIADFYLSVVTKD---SGVP----QMSSTGTVHITVIDQNDNP 3611
Score = 52.0 bits (123), Expect = 1e-06
Identities = 58/226 (25%), Positives = 94/226 (41%), Gaps = 47/226 (20%)
Query: 154 IARVKATDRDEDSSIIYSFK----TQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLET 209
I V A D+D + ++ + F ++ TG I ++PL+ + S+ Y L
Sbjct: 2687 ILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSH---YVLTI 2743
Query: 210 EATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFT 269
+++D G+ + S + V + +D+ + P FS F+
Sbjct: 2744 KSSDKGSPSQSTSVKVMINILDENDNA-PRFS------------------------QIFS 2778
Query: 270 FSVFENSPVDTLVGKVTFTDADWPFNNME-YTVVGGNLGTPPKFYIEPDTGVIKLLDSLN 328
V ENSP+ V +VT +D D N + Y+++ +L F I P TG I + LN
Sbjct: 2779 AHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASL----PFTINPSTGDIVISRPLN 2834
Query: 329 REIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
RE +Y+I V D D VTI V ++ND P
Sbjct: 2835 REDTDRYRIRVSAHDSGWTVSTD----------VTIFVTDINDNAP 2870
Score = 50.8 bits (120), Expect = 3e-06
Identities = 70/249 (28%), Positives = 111/249 (44%), Gaps = 41/249 (16%)
Query: 137 FPLDSINVT--EKKSVGEIIARVKATDRDEDSSII--YSFK----TQQKMFCLDPFTGTI 188
FP SI VT E S G + ATD D S+ + S++ + F LD I
Sbjct: 135 FPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLD-----I 189
Query: 189 TLLQPLNLDNPSNSKIY-SLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAII 247
TL NPS + L ++ + T Y V VE+ +P +
Sbjct: 190 TL-------NPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEP--------KRRGYL 234
Query: 248 TVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNL 306
V V V IN+ P+ +S + V E++ V + V +V DAD N ++ Y + +
Sbjct: 235 QVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQ--DE 292
Query: 307 GTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISV 366
GTP F ++P+TG+I + + L+ E QY + V+ D ++ +G A+ I +
Sbjct: 293 GTP--FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSL-------TGRAEALIQL 343
Query: 367 LNMNDEPPV 375
L++ND PV
Sbjct: 344 LDVNDNDPV 352
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/233 (25%), Positives = 97/233 (41%), Gaps = 43/233 (18%)
Query: 146 EKKSVGEIIARVKATD-RDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKI 204
E + V ++ + + R E S + F +D TG +++ QPL+ +
Sbjct: 2578 ENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQK--- 2634
Query: 205 YSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAI-ITVIVRVSRINELNPIG 263
Y + EA D G P FS+ + ITV+ +N+ PI
Sbjct: 2635 YVVWIEARDGG---------------------FPPFSSYEKLDITVL----DVNDNAPIF 2669
Query: 264 SASAFTFSVFEN-SPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDTGVI 321
F + EN SP L V+ D D P ++Y +V GN+ F I TG I
Sbjct: 2670 KEDPFISEILENLSPRKILT--VSAMDKDSGPNGQLDYEIVNGNMEN--SFSINHATGEI 2725
Query: 322 KLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+ + L+RE S Y + +K +D + + +S + +V I++L+ ND P
Sbjct: 2726 RSVRPLDREKVSHYVLTIKSSDKGSPS-------QSTSVKVMINILDENDNAP 2771
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/233 (23%), Positives = 91/233 (39%), Gaps = 39/233 (16%)
Query: 144 VTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSK 203
+ E G + V A+D D + + F ++P TG I L+ + N
Sbjct: 2373 IPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQFTINPSTGQIITSALLDRETKDN-- 2430
Query: 204 IYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIG 263
Y+L +D G+ +P+S S V+V V+ +N+ P
Sbjct: 2431 -YTLVVVCSDAGS--------------PEPLSSSTS---------VLVTVTDVNDNPPRF 2466
Query: 264 SASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDTGVIK 322
+ + + + V VT TDAD P + + Y++ G N KF+I+P G I
Sbjct: 2467 QHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRN---SEKFHIDPLRGAIM 2523
Query: 323 LLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
LN E + + VK D + P ++ + VT+ +N D P V
Sbjct: 2524 AAGPLNGASEVTFSVHVK----DGGSFP-----KTDSTTVTVRFVNKADFPKV 2567
Score = 42.7 bits (99), Expect = 8e-04
Identities = 58/282 (20%), Positives = 113/282 (40%), Gaps = 51/282 (18%)
Query: 150 VGEIIARVKATDRDEDSSIIYSFKT---QQKMFCLDPFTGTITLLQPLNLDNPSNSKIYS 206
+G ++ + A D DE ++ ++ F +D ++G + + L + IY+
Sbjct: 1543 IGSVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASAL----VPSQLIYN 1598
Query: 207 LETEATDNG--NNTSSYTFTVFVENVDDPISCDPSFST----GAAIITVIVRVSRINELN 260
L ATD G S+ T+ ++ +D P+ P + T G I T ++ I +
Sbjct: 1599 LIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVIS---IEAAS 1655
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGV 320
P GS + + + + VG++ F I TG+
Sbjct: 1656 PRGSEAPVEYYIVSVRCEEKTVGRL--------------------------FTIGRHTGI 1689
Query: 321 IKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPH 380
I+ L+RE + + + A P R+ A+V I++ ++ND PPV
Sbjct: 1690 IQTAAILDREQGACLYLVDVYAIEKSTAFP-----RTQRAEVEITLQDINDNPPVFPTDM 1744
Query: 381 LETQIYSTV-ESFHSAQLFSKDSPQ---EHLSYSIVGEQDES 418
L+ + + + QL + D+ + ++Y+I+ D+S
Sbjct: 1745 LDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDS 1786
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 14/132 (10%)
Query: 249 VIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGNLG 307
V + + IN+ P+ +V EN + + ++T DAD N + YT++ G
Sbjct: 1726 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISG--- 1782
Query: 308 TPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVL 367
F I+P++G + L+RE S+Y + V+ D +S ++ I+V
Sbjct: 1783 ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADD----------GLQSSDMRINITVS 1832
Query: 368 NMNDEPPVCNPP 379
++ND P + P
Sbjct: 1833 DVNDHTPKFSRP 1844
Score = 39.7 bits (91), Expect = 0.006
Identities = 45/194 (23%), Positives = 82/194 (42%), Gaps = 27/194 (13%)
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
NS +L T +T + + S + V +S P++ T ++ V +N+
Sbjct: 84 NSSTGALYTTSTIDRESLPSDVINLVV------LSSAPTYPTEVRVL-----VRDLNDNA 132
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME---YTVVGGNLGTPPKFYI--- 314
P+ + + E+S V T TD+D N ++ Y ++ GN + I
Sbjct: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
Query: 315 -EPDTGVIKLLDS--LNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
+ + L+ L+RE+ QY++ V+V D +R G QV ++V ++ND
Sbjct: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEP-------KRRGYLQVNVTVQDIND 245
Query: 372 EPPVCNPPHLETQI 385
PPV H + +
Sbjct: 246 NPPVFGSSHYQAGV 259
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 84.7 bits (208), Expect = 2e-16
Identities = 83/284 (29%), Positives = 123/284 (43%), Gaps = 46/284 (16%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLN 195
P+ ++V+E G + + ATD D +++ I+Y F LD TG +T
Sbjct: 472 PVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTA----- 526
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSR 255
S+++ E + + FTV + P P S A I+TV+
Sbjct: 527 ------SRVFDREEQ--------ERFIFTVTARDNGTP----PLQSQAAVIVTVLDE--- 565
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIE 315
N+ +P + + F F V EN P + VG +T TDAD N V L F ++
Sbjct: 566 -NDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK---AVTLSILNDNDNFVLD 621
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
P +GVIK S +RE +S Y VK TD RS TA+VTI+V+++ND PV
Sbjct: 622 PYSGVIKSNVSFDREQQSSYTFDVKATDGGQP-------PRSSTAKVTINVMDVNDNSPV 674
Query: 376 CNPPHLETQI----YSTVESFHSAQLFSKD---SPQEHLSYSIV 412
P T S + A++F+ D L Y+IV
Sbjct: 675 VISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIV 718
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/285 (24%), Positives = 116/285 (40%), Gaps = 39/285 (13%)
Query: 136 PFPLDSINVTEKKSVGEIIARVKATDRDEDSSII--YSFKTQQKMFCLDPFTGTITLLQP 193
P P+ +I++ E + ATD D + + Y Q +F LD
Sbjct: 143 PSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDI---------- 192
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
++ P K L + + +Y + VE+ P + AI+ V V
Sbjct: 193 --VETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQK------SSTAILQVTV-- 242
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPK-- 311
S +N+ P+ + EN+PV T V ++ TDAD N + G + K
Sbjct: 243 SDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRL 302
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F + TG+I + SL+RE + +K+ V L +D P R A VTI+V ++ND
Sbjct: 303 FALNNTTGLITVQRSLDREETAIHKVTV----LASDGSSTPAR-----ATVTINVTDVND 353
Query: 372 EPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQD 416
PP + ++ + I TV L KD ++ V ++D
Sbjct: 354 NPPNIDLRYIISPINGTV------YLSEKDPVNTKIALITVSDKD 392
Score = 49.3 bits (116), Expect = 8e-06
Identities = 54/252 (21%), Positives = 108/252 (42%), Gaps = 40/252 (15%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQ-----QKMFCLDPFTGTITLLQPL 194
+++ E VG + ++ ATD D ++ I Y F Q +++F L+ TG IT+ + L
Sbjct: 259 VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 195 NLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDD-PISCDPSFSTGAAIITVIVRV 253
+ + + K+ L A+D + + T T+ V +V+D P + D +
Sbjct: 319 DREETAIHKVTVL---ASDGSSTPARATVTINVTDVNDNPPNIDLRYI------------ 363
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY 313
++PI T + E PV+T + +T +D D N + + K
Sbjct: 364 -----ISPING----TVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAV 414
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
+ + +++ L+ E ++ + +D ++ + TA V + + + ND P
Sbjct: 415 YD-NQYLLETSSLLDYEGTKEFSFKIVASDSGKPSL-------NQTALVRVKLEDENDNP 466
Query: 374 PVCNPPHLETQI 385
P+ N P +E +
Sbjct: 467 PIFNQPVIELSV 478
Score = 49.3 bits (116), Expect = 8e-06
Identities = 73/329 (22%), Positives = 124/329 (37%), Gaps = 93/329 (28%)
Query: 31 LGPN----QIMAGSGVITATKIFNYETDPIRFLLIV---DTGR---LYRHVLTINIIDVP 80
LGPN + +GV+TA+++F+ E RF+ V D G + + + ++D
Sbjct: 508 LGPNASFFDLDRKTGVLTASRVFDREEQE-RFIFTVTARDNGTPPLQSQAAVIVTVLD-- 564
Query: 81 ESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLD 140
E+ N PKF+ + E+ P + ++ +T TD
Sbjct: 565 ENDN---SPKFTHNHFQFFVSENLPKYSTVGVITVTD----------------------- 598
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPS 200
D E+ ++ S F LDP++G I ++ D
Sbjct: 599 -------------------ADAGENKAVTLSILNDNDNFVLDPYSGVIK--SNVSFDREQ 637
Query: 201 NSKIYSLETEATDNG----NNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
S Y+ + +ATD G ++T+ T V N + P+ P +T ++ +
Sbjct: 638 QSS-YTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPL------- 689
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIE 315
SA SV V +V D D N ++YT+V GN F I+
Sbjct: 690 ---------SAIPGSV---------VAEVFAVDVDTGMNAELKYTIVSGN--NKGLFRID 729
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDL 344
P TG I L + +++ V ++DL
Sbjct: 730 PVTGNITLEEKPAPTDVGLHRLVVNISDL 758
Score = 37.0 bits (84), Expect = 0.042
Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 17/147 (11%)
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEY------ 299
+I + + V N+ P+ + S+ EN+ +++ + TD D FN +++
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG 184
Query: 300 -TVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSG 358
+V G ++ P+ P + + +L+RE + Y + +KV D Q+S
Sbjct: 185 QSVFGLDIVETPEGEKWPQ---LIVQQNLDREQKDTYVMKIKVED-------GGTPQKSS 234
Query: 359 TAQVTISVLNMNDEPPVCNPPHLETQI 385
TA + ++V ++ND PV +E I
Sbjct: 235 TAILQVTVSDVNDNRPVFKEGQVEVHI 261
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 84.7 bits (208), Expect = 2e-16
Identities = 83/284 (29%), Positives = 123/284 (43%), Gaps = 46/284 (16%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLN 195
P+ ++V+E G + + ATD D +++ I+Y F LD TG +T
Sbjct: 472 PVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTA----- 526
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSR 255
S+++ E + + FTV + P P S A I+TV+
Sbjct: 527 ------SRVFDREEQ--------ERFIFTVTARDNGTP----PLQSQAAVIVTVLDE--- 565
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIE 315
N+ +P + + F F V EN P + VG +T TDAD N V L F ++
Sbjct: 566 -NDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK---AVTLSILNDNDNFVLD 621
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
P +GVIK S +RE +S Y VK TD RS TA+VTI+V+++ND PV
Sbjct: 622 PYSGVIKSNVSFDREQQSSYTFDVKATDGGQP-------PRSSTAKVTINVMDVNDNSPV 674
Query: 376 CNPPHLETQI----YSTVESFHSAQLFSKD---SPQEHLSYSIV 412
P T S + A++F+ D L Y+IV
Sbjct: 675 VISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIV 718
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/285 (24%), Positives = 116/285 (40%), Gaps = 39/285 (13%)
Query: 136 PFPLDSINVTEKKSVGEIIARVKATDRDEDSSII--YSFKTQQKMFCLDPFTGTITLLQP 193
P P+ +I++ E + ATD D + + Y Q +F LD
Sbjct: 143 PSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDI---------- 192
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
++ P K L + + +Y + VE+ P + AI+ V V
Sbjct: 193 --VETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQK------SSTAILQVTV-- 242
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPK-- 311
S +N+ P+ + EN+PV T V ++ TDAD N + G + K
Sbjct: 243 SDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRL 302
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F + TG+I + SL+RE + +K+ V L +D P R A VTI+V ++ND
Sbjct: 303 FALNNTTGLITVQRSLDREETAIHKVTV----LASDGSSTPAR-----ATVTINVTDVND 353
Query: 372 EPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQD 416
PP + ++ + I TV L KD ++ V ++D
Sbjct: 354 NPPNIDLRYIISPINGTV------YLSEKDPVNTKIALITVSDKD 392
Score = 49.3 bits (116), Expect = 8e-06
Identities = 54/252 (21%), Positives = 108/252 (42%), Gaps = 40/252 (15%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQ-----QKMFCLDPFTGTITLLQPL 194
+++ E VG + ++ ATD D ++ I Y F Q +++F L+ TG IT+ + L
Sbjct: 259 VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 195 NLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDD-PISCDPSFSTGAAIITVIVRV 253
+ + + K+ L A+D + + T T+ V +V+D P + D +
Sbjct: 319 DREETAIHKVTVL---ASDGSSTPARATVTINVTDVNDNPPNIDLRYI------------ 363
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY 313
++PI T + E PV+T + +T +D D N + + K
Sbjct: 364 -----ISPING----TVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAV 414
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
+ + +++ L+ E ++ + +D ++ + TA V + + + ND P
Sbjct: 415 YD-NQYLLETSSLLDYEGTKEFSFKIVASDSGKPSL-------NQTALVRVKLEDENDNP 466
Query: 374 PVCNPPHLETQI 385
P+ N P +E +
Sbjct: 467 PIFNQPVIELSV 478
Score = 49.3 bits (116), Expect = 8e-06
Identities = 73/329 (22%), Positives = 124/329 (37%), Gaps = 93/329 (28%)
Query: 31 LGPN----QIMAGSGVITATKIFNYETDPIRFLLIV---DTGR---LYRHVLTINIIDVP 80
LGPN + +GV+TA+++F+ E RF+ V D G + + + ++D
Sbjct: 508 LGPNASFFDLDRKTGVLTASRVFDREEQE-RFIFTVTARDNGTPPLQSQAAVIVTVLD-- 564
Query: 81 ESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLD 140
E+ N PKF+ + E+ P + ++ +T TD
Sbjct: 565 ENDN---SPKFTHNHFQFFVSENLPKYSTVGVITVTD----------------------- 598
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPS 200
D E+ ++ S F LDP++G I ++ D
Sbjct: 599 -------------------ADAGENKAVTLSILNDNDNFVLDPYSGVIK--SNVSFDREQ 637
Query: 201 NSKIYSLETEATDNG----NNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
S Y+ + +ATD G ++T+ T V N + P+ P +T ++ +
Sbjct: 638 QSS-YTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPL------- 689
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIE 315
SA SV V +V D D N ++YT+V GN F I+
Sbjct: 690 ---------SAIPGSV---------VAEVFAVDVDTGMNAELKYTIVSGN--NKGLFRID 729
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDL 344
P TG I L + +++ V ++DL
Sbjct: 730 PVTGNITLEEKPAPTDVGLHRLVVNISDL 758
Score = 37.0 bits (84), Expect = 0.042
Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 17/147 (11%)
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEY------ 299
+I + + V N+ P+ + S+ EN+ +++ + TD D FN +++
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG 184
Query: 300 -TVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSG 358
+V G ++ P+ P + + +L+RE + Y + +KV D Q+S
Sbjct: 185 QSVFGLDIVETPEGEKWPQ---LIVQQNLDREQKDTYVMKIKVED-------GGTPQKSS 234
Query: 359 TAQVTISVLNMNDEPPVCNPPHLETQI 385
TA + ++V ++ND PV +E I
Sbjct: 235 TAILQVTVSDVNDNRPVFKEGQVEVHI 261
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 82.8 bits (203), Expect = 7e-16
Identities = 84/298 (28%), Positives = 134/298 (44%), Gaps = 43/298 (14%)
Query: 94 GTATLEIDEDYPLFQS-IYRVTATDEVFANGDR--LNVGGDHCARPFPLDS---INVTEK 147
G TL + DY Q + VTA+D ++ +NV + RP S ++V+E
Sbjct: 742 GLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDANTHRPVFQSSHYTVSVSED 801
Query: 148 KSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIY 205
+ VG IA + A D D E++ I Y + F +DP +GT+ + L+ +N Y
Sbjct: 802 RPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYEN---QVAY 858
Query: 206 SLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSA 265
+L A DNG S T T+ + +D N+ P
Sbjct: 859 TLTIMAQDNGIPQKSDTTTLEILILD------------------------ANDNAPQFLW 894
Query: 266 SAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLL 324
+ S+FE++P T + +V+ TD D P + YT GG+ G FYIEP +GVI+
Sbjct: 895 DFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDG-DGDFYIEPTSGVIRTQ 953
Query: 325 DSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLE 382
L+RE + Y + D + P PL S + ++ +++L++ND P+ LE
Sbjct: 954 RRLDRENVAVYNLWALAVDRGS---PTPL---SASVEIQVTILDINDNAPMFEKDELE 1005
Score = 63.5 bits (153), Expect = 4e-10
Identities = 68/264 (25%), Positives = 112/264 (42%), Gaps = 53/264 (20%)
Query: 142 INVTEKKSVGEIIARVKATDRDE--DSSIIYSFKTQQK--MFCLDPFTGTITLLQPLNLD 197
+ V E + + RV+ATDRD+ +++I YS + F L +G + ++ PL+ +
Sbjct: 466 VQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFE 525
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
+ YSL +A D G P + +++V +V +N
Sbjct: 526 DVQK---YSLSIKAQDGGR---------------------PPLINSSGVVSV--QVLDVN 559
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVV--------GGNLG- 307
+ PI +S F +V EN P+ V + DAD N + Y +V GG+ G
Sbjct: 560 DNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGP 619
Query: 308 -----TPP-KFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQ 361
TP F I +G I + L+RE Y V+ D + + S +
Sbjct: 620 KNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPM-------SSSTS 672
Query: 362 VTISVLNMNDEPPVCNPPHLETQI 385
V+I+VL++ND PV P E ++
Sbjct: 673 VSITVLDVNDNDPVFTQPTYELRL 696
Score = 60.1 bits (144), Expect = 5e-09
Identities = 59/241 (24%), Positives = 99/241 (41%), Gaps = 44/241 (18%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFK--TQQKMFCLDPFTG--TITLLQP 193
P + + E +VG + ++A DRD +S I Y + F L G ITL P
Sbjct: 690 PTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTGGNTRNRFALSSQRGGGLITLALP 749
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
L+ Y L A+D + +++ V++ V
Sbjct: 750 LDYKQEQQ---YVLAVTASDGTRSHTAH---------------------------VLINV 779
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY 313
+ N P+ +S +T SV E+ PV T + ++ D D N V+ + P+F
Sbjct: 780 TDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPV---PQFR 836
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
I+PD+G + + L+ E + Y + + D + IP Q+S T + I +L+ ND
Sbjct: 837 IDPDSGTMYTMMELDYENQVAYTLTIMAQD---NGIP----QKSDTTTLEILILDANDNA 889
Query: 374 P 374
P
Sbjct: 890 P 890
Score = 54.7 bits (130), Expect = 2e-07
Identities = 59/228 (25%), Positives = 102/228 (44%), Gaps = 44/228 (19%)
Query: 154 IARVKATDRDE--DSSIIYSFKTQQKM---FCLDPFTGTITLLQPLNLDNPSNSKIYSLE 208
I +V ATDRD + ++Y+F+ F ++P +G I + L+ +N + +Y+L
Sbjct: 911 ILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVA---VYNLW 967
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
A D G+ T P+S A + + V + IN+ P+
Sbjct: 968 ALAVDRGSPT--------------PLS---------ASVEIQVTILDINDNAPMFEKDEL 1004
Query: 269 TFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSL 327
V EN+PV ++V K+ D D P + Y +V G++ F ++ G ++ + L
Sbjct: 1005 ELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDM--RHFFQLDLLNGDLRAMVEL 1062
Query: 328 NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
+ E+ +Y + V+ T PL R A V I +++ ND PPV
Sbjct: 1063 DFEVRREYVLVVQATSA-------PLVSR---ATVHILLVDQNDNPPV 1100
Score = 50.4 bits (119), Expect = 4e-06
Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 43/258 (16%)
Query: 136 PFPLDSINVTEKKSVGEIIARVKA--TDRDEDSSIIYSFK-----TQQKMFCLDPFTGTI 188
P P + + E + G +I ++ A T E+ + Y + + F +D TG +
Sbjct: 246 PMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGAV 305
Query: 189 TLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIIT 248
S + ET+ T + V+ VD S P +T IT
Sbjct: 306 -----------STDSVLDRETKETH----------VLRVKAVD--YSTPPRSAT--TYIT 340
Query: 249 VIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLG 307
V+V+ + N+ +P+ S + V EN V V + +D D P N N+ Y V+GG
Sbjct: 341 VLVKDT--NDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWD 398
Query: 308 TPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVL 367
F + +GV+ L+RE ++Y++ V+ D + P PL S TA V I V
Sbjct: 399 V---FQLNESSGVVSTRAVLDREEAAEYQLLVEANDQGRN--PGPL---SATATVYIEVE 450
Query: 368 NMNDEPPVCNPPHLETQI 385
+ ND P + + Q+
Sbjct: 451 DENDNYPQFSEQNYVVQV 468
Score = 35.4 bits (80), Expect = 0.12
Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 13/152 (8%)
Query: 268 FTFSVFENSPVDTLVGKV-TFTDADWPFNNMEYTVVG-GNLGTPPKFYIEPDTGVIKLLD 325
+ ++FEN P TL+ ++ + + Y + G + + F I+ TG +
Sbjct: 250 YQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGAVSTDS 309
Query: 326 SLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQI 385
L+RE + + + VK D RS T +T+ V + ND PV ++
Sbjct: 310 VLDRETKETHVLRVKAVDYSTPP-------RSATTYITVLVKDTNDHSPVFEQSEYRERV 362
Query: 386 YSTVESFH---SAQLFSKDSP-QEHLSYSIVG 413
+E + + + +DSP +L Y ++G
Sbjct: 363 RENLEVGYEVLTIRASDRDSPINANLRYRVLG 394
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 82.0 bits (201), Expect = 1e-15
Identities = 72/251 (28%), Positives = 109/251 (43%), Gaps = 33/251 (13%)
Query: 144 VTEKKSVGEIIARVKATDRDE-----DSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
V E VG + +VKATD D+ + ++YS Q F +DP TG I P N+D
Sbjct: 169 VPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQPYFSIDPKTGVIRTALP-NMDR 227
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
+ Y + +A D G T V + ++ +N+
Sbjct: 228 EVKEQ-YQVLIQAKDMGGQLGGLAGTTIVN----------------------ITLTDVND 264
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPD 317
P S F V E+SP+ + +G++ D D+ N +EY +V G+ G + D
Sbjct: 265 NPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDED 324
Query: 318 T--GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
T GVIKL L+ E + Y V+ ++L D TA V ISVL++ DEPPV
Sbjct: 325 TQEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDV-DEPPV 383
Query: 376 CNPPHLETQIY 386
+ P ++Y
Sbjct: 384 FSKPLYTMEVY 394
Score = 64.3 bits (155), Expect = 2e-10
Identities = 43/126 (34%), Positives = 66/126 (52%), Gaps = 6/126 (4%)
Query: 250 IVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTP 309
I++V IN+ P + +V E SPV V +V TDAD P VV L
Sbjct: 147 IIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQ 206
Query: 310 PKFYIEPDTGVIK-LLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLN 368
P F I+P TGVI+ L +++RE++ QY++ ++ D+ L +GT V I++ +
Sbjct: 207 PYFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQ-----LGGLAGTTIVNITLTD 261
Query: 369 MNDEPP 374
+ND PP
Sbjct: 262 VNDNPP 267
Score = 62.8 bits (151), Expect = 7e-10
Identities = 66/268 (24%), Positives = 117/268 (43%), Gaps = 30/268 (11%)
Query: 136 PFPLDSINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQP 193
P + + V E +G I R++A D D +++ I Y+ D T T
Sbjct: 270 PKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGV 329
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF-STGAAIITVIVR 252
+ L P + ET+ +YTF V N + D F S G T V+
Sbjct: 330 IKLKKPLD-----FETK--------KAYTFKVEASN----LHLDHRFHSAGPFKDTATVK 372
Query: 253 VSRIN-ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPK 311
+S ++ + P+ S +T V+E++PV T++G VT D D + + Y + + G
Sbjct: 373 ISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDG-DSY 431
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F I+ + G I + L+RE +QY ++ + + N + + + I+VL++N+
Sbjct: 432 FTIDGNEGTIATNELLDRESTAQYNFSIIASKVSNPLL-------TSKVNILINVLDVNE 484
Query: 372 EPPVCNPPHLETQIYSTVESFHSAQLFS 399
PP + P+ ET + + Q+ S
Sbjct: 485 FPPEISVPY-ETAVCENAKPGQIIQIVS 511
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 79.3 bits (194), Expect = 7e-15
Identities = 101/359 (28%), Positives = 156/359 (43%), Gaps = 66/359 (18%)
Query: 86 TADPKFS----SGTATLEIDEDYPLFQSIY-------------RVTATDEVFANGDRLNV 128
+AD +FS SG LE D L Q++Y R+TAT V + L++
Sbjct: 3167 SADGQFSINELSGIIQLEKPLDREL-QAVYTLSLKAVDQGLPRRLTATGTVIVSV--LDI 3223
Query: 129 GGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSS--IIYSFKT--QQKMFCLDPF 184
+ + V+E VG + +V A RD +++ I YS + + F +D
Sbjct: 3224 NDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSK 3283
Query: 185 TGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGA 244
TG + +++ NLD S+ + Y L EATD G PS S
Sbjct: 3284 TGAVFIIE--NLDYESSHEYY-LTVEATDGGT---------------------PSLSD-- 3317
Query: 245 AIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVG 303
+ TV V V+ IN+ P+ S +T + E++ ++ V V DAD P N ++ Y+++
Sbjct: 3318 -VATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIID 3376
Query: 304 GNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVT 363
GN G+ F I+P G +K+ L+RE S Y + V+ + DN + P R T V
Sbjct: 3377 GNQGS--SFTIDPVRGEVKVTKLLDRETISGYTLTVQAS--DNGSPP-----RVNTTTVN 3427
Query: 364 ISVLNMNDEPPVCNPPHLETQIYSTVE-SFHSAQLFSKDSPQEH----LSYSIVGEQDE 417
I V ++ND PV + + I F QL D H ++IV DE
Sbjct: 3428 IDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDE 3486
Score = 77.4 bits (189), Expect = 3e-14
Identities = 75/274 (27%), Positives = 127/274 (46%), Gaps = 51/274 (18%)
Query: 113 VTATDEVFANGDRLNV-------GGDHCARPFPLDSINVTEKKSVGEIIARVKATDRD-- 163
+TATD F++ + V C + D+I E G++I ++ ATD D
Sbjct: 2996 ITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTI--PEDVLPGKLIMQISATDADIR 3053
Query: 164 EDSSIIYSFK-TQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYT 222
++ I Y+ + + F L+P TG + PL+ + + +Y L ATD G +
Sbjct: 3054 SNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQA---VYHLLVRATDGGGRFCQAS 3110
Query: 223 FTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLV 282
+ +E+V+D P F SA + +VFEN+ TL+
Sbjct: 3111 IVLTLEDVNDNA---PEF-----------------------SADPYAITVFENTEPGTLL 3144
Query: 283 GKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKV 341
+V TDAD N + Y+++ G +F I +G+I+L L+RE+++ Y +++K
Sbjct: 3145 TRVQATDADAGLNRKILYSLIDSADG---QFSINELSGIIQLEKPLDRELQAVYTLSLKA 3201
Query: 342 TDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
D +P R+ + T V +SVL++ND PPV
Sbjct: 3202 VD---QGLP---RRLTATGTVIVSVLDINDNPPV 3229
Score = 70.1 bits (170), Expect = 4e-12
Identities = 81/297 (27%), Positives = 129/297 (43%), Gaps = 44/297 (14%)
Query: 150 VGEIIARVKATDRDEDSSIIYSFKTQQKM--FCLDPFTGTITLLQPLNLDNPSNSKIYSL 207
VGE I V A D DE + Y + ++ F L+P +G ++L + L + +SL
Sbjct: 584 VGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSL 643
Query: 208 ETEATDNGNNTSSY--TFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSA 265
ATD N + TV + + C+ TG A + + ++ + N+L+ G
Sbjct: 644 RITATDGENFATPLYINITVAASHKLVNLQCE---ETGVAKM-LAEKLLQANKLHNQGEV 699
Query: 266 SAFTFS--------------------VFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGG 304
F V EN PV + V + TD D FN + Y V GG
Sbjct: 700 EDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGG 759
Query: 305 NLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
N + F I+ +TG++K+L L+RE +Y + + V DL IP Q++ + +
Sbjct: 760 NEDSC--FMIDMETGMLKILSPLDRETTDKYTLNITVYDL---GIP----QKAAWRLLHV 810
Query: 365 SVLNMNDEPPVCNPPHLETQIYSTVESFHS----AQLFSKD-SPQEHLSYSIVGEQD 416
V++ ND PP ++ S + HS + KD P H++YSIV + D
Sbjct: 811 VVVDANDNPPEFLQESYFVEV-SEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTD 866
Score = 69.7 bits (169), Expect = 6e-12
Identities = 56/196 (28%), Positives = 95/196 (48%), Gaps = 35/196 (17%)
Query: 154 IARVKATDRDEDSSIIYSFKTQQ-----KMFCLDPFTGTITLLQPLNLDNPSNSKIYSLE 208
I ++ A D+DE + +IY+ ++ + K F LDP TG++ + L+
Sbjct: 1475 ILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSE-------------KLD 1521
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
EA +T TV V + D P+ + ++V VS N+ P +AS++
Sbjct: 1522 HEAVHQ------HTLTVMVRDQDVPVKRN--------FARIVVNVSDTNDHAPWFTASSY 1567
Query: 269 TFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSL 327
V+E++ V ++V +VT D D N + Y++ GN+G F I+P G IK L
Sbjct: 1568 KGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGN--SFMIDPVLGSIKTAKEL 1625
Query: 328 NREIESQYKIAVKVTD 343
+R +++Y + VK TD
Sbjct: 1626 DRSNQAEYDLMVKATD 1641
Score = 65.1 bits (157), Expect = 1e-10
Identities = 73/292 (25%), Positives = 120/292 (41%), Gaps = 55/292 (18%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQ--KMFCLDPFTGTITLLQPLN 195
P S + E V + V+A E + YS F ++ TG I ++ PL+
Sbjct: 2185 PFYSAEIAESIQVHSPVVHVQANS-PEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLD 2243
Query: 196 LD-NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVS 254
+ +P+ Y L ATD+ + F + VDD
Sbjct: 2244 FEAHPA----YKLSIRATDSLTGAHAEVFVDII--VDD---------------------- 2275
Query: 255 RINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADW-PFNNMEYTVVGGNLGTPPKFY 313
IN+ P+ + ++ ++ E S + T V +V TD+D P + Y + G + + F+
Sbjct: 2276 -INDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFH 2334
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
++ TG+I LL +L+ E Q+ I V+ A+ + S VT+ V ++ND
Sbjct: 2335 VDSSTGLISLLRTLDYEQSRQHTIFVR-------AVDGGMPTLSSDVIVTVDVTDLND-- 2385
Query: 374 PVCNPPHLETQIYSTVESFHS--------AQLFSKDSPQ-EHLSYSIVGEQD 416
NPP E QIY S H+ + + DS + L YSI+ D
Sbjct: 2386 ---NPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGND 2434
Score = 58.9 bits (141), Expect = 1e-08
Identities = 77/306 (25%), Positives = 127/306 (41%), Gaps = 65/306 (21%)
Query: 146 EKKSVGEIIARVKATDRDE--DSSIIYSFK--TQQKMFCLDPFTGTITLLQPLNLDNPSN 201
E+ + E + V ATD+DE ++ I YS + + F ++P TG ++
Sbjct: 1263 ERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVS------------ 1310
Query: 202 SKIYS-------LETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVS 254
SK +S L +A DNG S T + +E + P PS
Sbjct: 1311 SKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKP---KPS--------------- 1352
Query: 255 RINELNPIG-SASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY 313
L PI S FTF+V E+ PV ++G ++ P + + + GGN + F
Sbjct: 1353 ----LEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIP---LWFDITGGNYDS--HFD 1403
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
++ TG I + L+ E +S Y + V+ TD + QV I V++ ND
Sbjct: 1404 VDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL----------TQVFIKVIDTNDHR 1453
Query: 374 PVCNPPHLETQI-YSTVESFHSAQLFSKDSPQEH-LSYSIVGEQD--ESRKKRLEKMSLS 429
P + E I T Q+ + D +++ L Y++ +D +K RL+ + S
Sbjct: 1454 PQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGS 1513
Query: 430 SYYFKK 435
Y +K
Sbjct: 1514 LYTSEK 1519
Score = 58.2 bits (139), Expect = 2e-08
Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 63/288 (21%)
Query: 144 VTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKM--FCLDPFTGTITLLQPLNLDNP 199
V E VG ++ V A D D D I YS + + F + TG I
Sbjct: 1043 VKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVI----------- 1091
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
ET + +TS Y TVF + D ++ I + + V +N+
Sbjct: 1092 --------ETSDRLDRESTSHYWLTVF--------ATDQGVVPLSSFIEIYIEVEDVNDN 1135
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFY-IEPD 317
P S + + ENSP D V ++ D D N+ + Y + GN P F+ I P
Sbjct: 1136 APQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGN---PQGFFSIHPK 1192
Query: 318 TGVIKLLD-SLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVC 376
TG+I L+RE + ++ + V VT DN + P +S A+V + +L+ ND P
Sbjct: 1193 TGLITTTSRKLDREQQDEHILEVTVT--DNGSPP-----KSTIARVIVKILDENDNKP-- 1243
Query: 377 NPPHLETQIYSTVESFHSAQLFSKDSP-------QEHLSYSIVGEQDE 417
++ F+ +L ++ P +E L + I ++DE
Sbjct: 1244 ----------QFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDE 1281
Score = 52.0 bits (123), Expect = 1e-06
Identities = 58/282 (20%), Positives = 111/282 (39%), Gaps = 48/282 (17%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNP 199
+ V+E K V I +V+ATD+D + + YS T F +D TG + + +PL+ +
Sbjct: 829 VEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQ 888
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
+SL+ EA D TV V+ V + +N+
Sbjct: 889 HE---HSLKIEARDQAREEPQLFSTVVVK----------------------VSLEDVNDN 923
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDT 318
P + V E+ P T++ + D D + Y+++ G F ++ +
Sbjct: 924 PPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEG---NFDVDKLS 980
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G ++++ L+ E + Y + V+ D S T V + V+++N+ +P
Sbjct: 981 GAVRIVQQLDFEKKQVYNLTVRAKDKGKPV------SLSSTCYVEVEVVDVNEN---LHP 1031
Query: 379 PHLETQIYSTVESFHSAQLFSKDSPQEHLSYSIVGEQDESRK 420
P SF +D+P L ++ +++R+
Sbjct: 1032 P--------VFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARR 1065
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 41/244 (16%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQ-QKMFCLDPFTGTITLLQPLNLDN 198
+ V E G +I ++A D D + + YS + F +D +G + ++Q L+ +
Sbjct: 934 VKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEK 993
Query: 199 PSNSKIYSLETEATDNGNNTS-SYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
++Y+L A D G S S T V VE VD + P
Sbjct: 994 ---KQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHP------------------- 1031
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGN-LGTPPKFYIE 315
P+ S+ +V E++PV +LV V+ D D + + Y++ G+ +G F I
Sbjct: 1032 ---PVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGV---FKIG 1085
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
+TGVI+ D L+RE S Y + V T D +P S ++ I V ++ND P
Sbjct: 1086 EETGVIETSDRLDRESTSHYWLTVFAT--DQGVVP-----LSSFIEIYIEVEDVNDNAPQ 1138
Query: 376 CNPP 379
+ P
Sbjct: 1139 TSEP 1142
Score = 49.3 bits (116), Expect = 8e-06
Identities = 48/211 (22%), Positives = 89/211 (42%), Gaps = 39/211 (18%)
Query: 179 FCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDP 238
F +D TGTI + +PL+ + SN Y+L EATD
Sbjct: 1402 FDVDKGTGTIIVAKPLDAEQKSN---YNLTVEATD------------------------- 1433
Query: 239 SFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME 298
T + V ++V N+ P S S + + E++ +T + +++ D D N +
Sbjct: 1434 --GTTTILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQD-EKNKLI 1490
Query: 299 YTVVGG-NLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRS 357
YT+ + + KF ++P TG + + L+ E Q+ + V V D D + +
Sbjct: 1491 YTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQD-------VPVKR 1543
Query: 358 GTAQVTISVLNMNDEPPVCNPPHLETQIYST 388
A++ ++V + ND P + ++Y +
Sbjct: 1544 NFARIVVNVSDTNDHAPWFTASSYKGRVYES 1574
Score = 49.3 bits (116), Expect = 8e-06
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 51/245 (20%)
Query: 144 VTEKKSVGEIIARVKATDRDEDSS--IIYSFKTQQKMFCLDPF-----TGTITLLQPLNL 196
+ E G + +++A+D D ++ ++YS Q + ++ F TG IT L+ L+
Sbjct: 2818 IVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDH 2877
Query: 197 DNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
+ N Y ++ A+D+G + + V V V+ +
Sbjct: 2878 EKRDN---YQIKVVASDHGEKIQLSSTAI-----------------------VDVTVTDV 2911
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME--YTVVGGN-LGTPPKFY 313
N+ P +A + +V E+ P ++ ++ TDAD N + Y + GG+ LG +F
Sbjct: 2912 NDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLG---QFA 2968
Query: 314 IE--PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
+E + + + L+RE Y + + TD S A V + VL+ ND
Sbjct: 2969 VETIQNEWKVYVKKPLDREKRDNYLLTITATD----------GTFSSKAIVEVKVLDAND 3018
Query: 372 EPPVC 376
PVC
Sbjct: 3019 NSPVC 3023
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/255 (23%), Positives = 108/255 (42%), Gaps = 49/255 (19%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQK--MFCLDPFTGTITLLQPLNLDN 198
S+ ++E S+G + V A + SS++Y K F ++P +GTI + L+ +
Sbjct: 1673 SVELSETVSIGSFVGMVTAHSQ---SSVVYEIKDGNTGDAFDINPHSGTIITQKALDFET 1729
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
IY+L + T+ +++ TV+V + N+
Sbjct: 1730 ---LPIYTLIIQGTNMAGLSTN--------------------------TTVLVHLQDEND 1760
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGK-------VTFTDADWPFNNM-EYTVVGGNLGTPP 310
P+ + +T + E++ ++++V + DAD N + Y +V ++ T
Sbjct: 1761 NAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHT-- 1818
Query: 311 KFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMN 370
F I+ TG I + SL+ E S + V+V D+ P A VT+ V+++N
Sbjct: 1819 YFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGT-----PRLFAEYAANVTVHVIDIN 1873
Query: 371 DEPPVCNPPHLETQI 385
D PPV P E +
Sbjct: 1874 DCPPVFAKPLYEASL 1888
Score = 47.8 bits (112), Expect = 2e-05
Identities = 59/264 (22%), Positives = 108/264 (40%), Gaps = 47/264 (17%)
Query: 144 VTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQ--KMFCLDPFTGTITLLQPLNLDNP 199
V E +VG ++ +V A D+D +++ ++YS ++ F +DP G+I + L +
Sbjct: 1571 VYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKEL---DR 1627
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
SN Y L +ATD G+ S I +V + V+ +
Sbjct: 1628 SNQAEYDLMVKATDKGSPPMS------------------------EITSVRIFVTIADNA 1663
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTG 319
+P ++ ++ + E + + VG VT +++ Y + GN G F I P +G
Sbjct: 1664 SPKFTSKEYSVELSETVSIGSFVGMVTAHSQ----SSVVYEIKDGNTG--DAFDINPHSG 1717
Query: 320 VIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPP 379
I +L+ E Y + ++ T++ S V + + + ND PV
Sbjct: 1718 TIITQKALDFETLPIYTLIIQGTNMAG---------LSTNTTVLVHLQDENDNAPVFMQA 1768
Query: 380 HLETQIYSTVESFHSAQLFSKDSP 403
T + S S +S L ++ P
Sbjct: 1769 EY-TGLISESASINSVVLTDRNVP 1791
Score = 47.4 bits (111), Expect = 3e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 15/170 (8%)
Query: 207 LETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSAS 266
L+ E + + T Y F++ C A + V ++V N+ +P+ +S
Sbjct: 2760 LKLEKSLDHETTKWYQFSILAR-------CTQDDHEMVASVDVSIQVKDANDNSPVFESS 2812
Query: 267 AFTFSVFENSPVDTLVGKVTFTDADWPFNN--MEYTVVGGNLGTPPKFYIEPDTGVIKLL 324
+ + EN P + V ++ +DAD N M ++ F I +TG I L
Sbjct: 2813 PYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTL 2872
Query: 325 DSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
L+ E Y+I V +D Q S TA V ++V ++ND PP
Sbjct: 2873 KELDHEKRDNYQIKVVASDHGEKI------QLSSTAIVDVTVTDVNDSPP 2916
Score = 45.8 bits (107), Expect = 9e-05
Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 31/171 (18%)
Query: 141 SINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
S+++ E ++ IARV ATD D + YSFK + MF + P +G I L L+
Sbjct: 155 SVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDY-- 212
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTG-AAIITVIVRVSRIN 257
+K+Y +E A D G S+G +++ + V + + N
Sbjct: 213 -LETKLYEMEILAADRGMKLYG--------------------SSGISSMAKLTVHIEQAN 251
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN--MEYTVVGGNL 306
E P+ +A + S + P + VT D D N ++V G+L
Sbjct: 252 ECAPVITAVTLSPSELDRDPAYAI---VTVDDCDQGANGDIASLSIVAGDL 299
Score = 44.3 bits (103), Expect = 3e-04
Identities = 72/296 (24%), Positives = 115/296 (38%), Gaps = 52/296 (17%)
Query: 144 VTEKKSVGEIIARVKATDRDEDS--SIIYSFKT--QQKMFCLDPFTGTITLLQPLNLDNP 199
++E G + VKA D D + YS + K F +D TG ITL NL
Sbjct: 2399 ISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLS---NLHRH 2455
Query: 200 SNSKIYSLETEATDNGNNTSSYTF-TVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
+ YSL +D +S+ TV N+ P + A
Sbjct: 2456 ALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELA------------- 2502
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPD 317
EN+P+ TLV +V TD D + ++ Y +V N +FYI +
Sbjct: 2503 ---------------ENAPLHTLVMEVKTTDGDSGIYGHVTYHIV--NDFAKDRFYIN-E 2544
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
G I L+ L+RE ++ I+V++ D + V + + + ND P
Sbjct: 2545 RGQIFTLEKLDRETPAEKVISVRLMAKDAGG-------KVAFCTVNVILTDDNDNAPQFR 2597
Query: 378 PPHLETQIYSTVESFHS-AQLFSKDSPQ---EHLSYSIVGEQDESRKKRLEKMSLS 429
E I S+ S ++ + D+ + ++Y+I + ES K+ LE LS
Sbjct: 2598 ATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEAD-SESVKENLEINKLS 2652
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/243 (21%), Positives = 98/243 (40%), Gaps = 46/243 (18%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSS--IIYSFKTQ----QKMFCLDPFTGTITLLQPLN 195
+N+ + G + +V A+D DE S+ I Y+ + ++ ++ +G IT
Sbjct: 2603 VNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINKLSGVIT------ 2656
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSR 255
+ + LE E FT FV VD+ + +++ V V++
Sbjct: 2657 ----TKESLIGLENE-----------FFTFFVRAVDN------GSPSKESVVLVYVKILP 2695
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNL---GTPPKF 312
P S +TF+V E+ P+ T + + + + Y++V GN F
Sbjct: 2696 PEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHS----GTVLYSLVKGNTPESNRDESF 2751
Query: 313 YIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDE 372
I+ +G +KL SL+ E Y+ ++ +D + + V+I V + ND
Sbjct: 2752 VIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDD------HEMVASVDVSIQVKDANDN 2805
Query: 373 PPV 375
PV
Sbjct: 2806 SPV 2808
Score = 38.9 bits (89), Expect = 0.011
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 249 VIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGT 308
V V+V N+L P+ S ++++ S+ EN+ + T + +V+ TDAD N Y
Sbjct: 135 VRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDR--- 191
Query: 309 PPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTD 343
F I P +GVI L L+ Y++ + D
Sbjct: 192 TDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAAD 226
Score = 37.0 bits (84), Expect = 0.042
Identities = 49/214 (22%), Positives = 91/214 (42%), Gaps = 45/214 (21%)
Query: 166 SSIIYSFKTQ--QKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTF 223
S + Y FK+ + F L+ TG I++L+P+ ++ + LE +D +T
Sbjct: 396 SHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAH---FELEVTTSDRKASTK---- 448
Query: 224 TVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVG 283
V+V+V N P + +A+ + EN P+ T V
Sbjct: 449 -------------------------VLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVM 483
Query: 284 KVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQ-YKIAVKV 341
++ D D N + Y++ NL P F I+ TG + ++L+ E+ + Y + ++
Sbjct: 484 SLSAVDPDEGENGYVTYSI--ANLNHVP-FAIDHFTGAVSTSENLDYELMPRVYTLRIRA 540
Query: 342 TDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
+D +P +R TI++ N+ND P+
Sbjct: 541 SDW---GLP---YRREVEVLATITLNNLNDNTPL 568
>gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens]
Length = 3354
Score = 77.8 bits (190), Expect = 2e-14
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 12/175 (6%)
Query: 244 AAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVV 302
AA I V + + IN+ NPI ++ +VFE+ PV T++ VT TDAD F +EY++
Sbjct: 2383 AAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLG 2442
Query: 303 GGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQV 362
G KF I P TG I +L SL+RE + Y + D D + +R + QV
Sbjct: 2443 DGE----SKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASN---RRENSVQV 2495
Query: 363 TISVLNMNDEPPVCNPPHLETQIYSTVESFHSAQLF----SKDSPQEHLSYSIVG 413
I VL++ND P + P T +Y + S + P L+YS+ G
Sbjct: 2496 VIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEG 2550
Score = 70.1 bits (170), Expect = 4e-12
Identities = 65/264 (24%), Positives = 117/264 (44%), Gaps = 37/264 (14%)
Query: 141 SINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
S+ + E VG I V ATD D S++YSF+ + F +D G +T+++ L+ +
Sbjct: 138 SVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYE- 196
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
++ Y L ATD ++ P+S + + + ++ + +
Sbjct: 197 --TTQAYQLTVNATD--------------QDKTRPLS---------TLANLAIIITDVQD 231
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPD 317
++PI ++ +++E+SP T V +T D D + YT+V GN T F ++
Sbjct: 232 MDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGN--TNSIFALDYI 289
Query: 318 TGVIKLLDSLNRE---IESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+GV+ L L+RE + + VK T+L++D P + T I V+++ND P
Sbjct: 290 SGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPS---DATVTTTFNILVIDINDNAP 346
Query: 375 VCNPPHLETQIYSTVESFHSAQLF 398
N I + + LF
Sbjct: 347 EFNSSEYSVAITELAQVGFALPLF 370
Score = 59.7 bits (143), Expect = 6e-09
Identities = 83/339 (24%), Positives = 135/339 (39%), Gaps = 52/339 (15%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDS--SIIYSFKTQQKMFCLDPFTGTITLLQPLN 195
PL +I++ E +VG + V ATD D + + Y F F LD TG I L+ L+
Sbjct: 463 PLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLD 522
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSR 255
+ ++L A D G ++ + V +V+D +
Sbjct: 523 YELIQR---FTLTIIARDGGGEETTGRVRINVLDVNDNV--------------------- 558
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGN-LGTPPKFY 313
P A+ ++ EN P T + ++ TD D P NN + Y++V + G+
Sbjct: 559 -----PTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDIS 613
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
+ GVI + L+ E S I + V +D P + T VTI V + ND P
Sbjct: 614 LYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPP-----LNSTVPVTIEVFDENDNP 668
Query: 374 PVCNPPHLETQIY------STVESFHSAQL-FSKDSPQEHLSYSIVGEQD---ESRKKRL 423
P + P + +TV ++ L S++ QE + YS+ G +R +
Sbjct: 669 PTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEI 728
Query: 424 EKMSLSSYYFKKCFTDVIRADN----HNNDYFPSVTNIT 458
SL K + ++RA + HN + NIT
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNIT 767
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/299 (23%), Positives = 126/299 (42%), Gaps = 42/299 (14%)
Query: 112 RVTATDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYS 171
+ T++ VF N LN D + P + V E G I +V A D DE + + S
Sbjct: 869 KATSSATVFVNLLDLN-DNDPTFQNLPFVA-EVLEGIPAGVSIYQVVAIDLDEGLNGLVS 926
Query: 172 FKTQQKM----FCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFV 227
++ M F ++ +G + L+ + + Y L A+D G T S T T+ +
Sbjct: 927 YRMPVGMPRMDFLINSSSGVVVTTTELDRERIAE---YQLRVVASDAGTPTKSSTSTLTI 983
Query: 228 ENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTF 287
+D +N+ P + + SV E+ P + V +
Sbjct: 984 HVLD------------------------VNDETPTFFPAVYNVSVSEDVPREFRVVWLNC 1019
Query: 288 TDADWPFN-NMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDN 346
TD D N + Y + GGN+ KF + V++ + L+RE + Y + ++ +DN
Sbjct: 1020 TDNDVGLNAELSYFITGGNVDG--KFSVGYRDAVVRTVVGLDRETTAAYMLILEA--IDN 1075
Query: 347 DAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYSTVESFHS-AQLFSKDSPQ 404
+ ++ +GTA V ++VL++ND P+ E + + HS QL + D+ +
Sbjct: 1076 GPVG---KRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADE 1131
Score = 57.4 bits (137), Expect = 3e-08
Identities = 82/318 (25%), Positives = 125/318 (39%), Gaps = 62/318 (19%)
Query: 60 LIVDTG--RLYRHVLTINIIDVPESPNCTADPKFSSGTA--TLEIDE-----------DY 104
+++D G L ++TI +D+ E PN T +G T ID DY
Sbjct: 1641 VLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDY 1700
Query: 105 PLFQSIYR--VTATDEVFANGDRL--------NVGGDHCARP-FPLD---SINVTEKKSV 150
+ Y VTATD+ RL NV + P FP D VTE +
Sbjct: 1701 EISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQP- 1759
Query: 151 GEIIARVKATDRDE--DSSIIYSFKTQQKM--FCLDPFTGTITLLQPLNLDNPSNSKIYS 206
G + A DRD + + YS + F + P G + + + + LD + + Y+
Sbjct: 1760 GPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIA-FYN 1818
Query: 207 LETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSAS 266
L A D G S T V + RV IN+ +P+
Sbjct: 1819 LTICARDRGMPPLSSTMLVGI------------------------RVLDINDNDPVLLNL 1854
Query: 267 AFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPDTGVIKLLD 325
++ ENSPV + V V +DAD N + + + GN F+I TG++ +
Sbjct: 1855 PMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGN--RERAFFINATTGIVTVNR 1912
Query: 326 SLNREIESQYKIAVKVTD 343
L+RE +YK+ + V D
Sbjct: 1913 PLDRERIPEYKLTISVKD 1930
Score = 57.4 bits (137), Expect = 3e-08
Identities = 93/366 (25%), Positives = 149/366 (40%), Gaps = 80/366 (21%)
Query: 62 VDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFA 121
+D R+ + LTI++ D PE+P + ++++PLF + T EV
Sbjct: 1914 LDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFT---KSTYQAEVME 1970
Query: 122 NGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFK---TQQKM 178
N PL +N G I+A D D+D + +++ Q +
Sbjct: 1971 NSPAGT----------PLTVLN-------GPILA----LDADQDIYAVVTYQLLGAQSGL 2009
Query: 179 FCLDPFTGTITLLQPLNLDNPSNSK-IYSLETEATDNG--NNTSSYTFTVFVENVDDPIS 235
F ++ TG +T+ + +D + S I L A D G N+T+ T+ +DD
Sbjct: 2010 FDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITI----LDD--- 2062
Query: 236 CDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN 295
N+ P S + T + EN P V +VT TD D N
Sbjct: 2063 ---------------------NDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLN 2101
Query: 296 -NMEYTVVGGNLGTPPKFYIEPDTGVIKLLD-SLNREIESQYKIAVKVTDLDNDAIPDPL 353
+ Y + G +F I TGVI++ + +++RE + Y++ V T D +P
Sbjct: 2102 GELVYRI---EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVAT--DRGTVP--- 2153
Query: 354 RQRSGTAQVTISVLNMND-EPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEH-----L 407
SGTA VTI + ++ND P NP Q S +ES + + + +H L
Sbjct: 2154 --LSGTAIVTILIDDINDSRPEFLNP----IQTVSVLESAEPGTVIANITAIDHDLNPKL 2207
Query: 408 SYSIVG 413
Y IVG
Sbjct: 2208 EYHIVG 2213
Score = 57.4 bits (137), Expect = 3e-08
Identities = 99/373 (26%), Positives = 153/373 (41%), Gaps = 103/373 (27%)
Query: 28 GAGLGPNQIMAGSGVITATK--IFNYE--TDPIRFLLIV--DTGRLYRHV-LTINIIDVP 80
GA G I + +GV+T I + E + PI LL++ D G L L I I+D
Sbjct: 2004 GAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDN 2063
Query: 81 ESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLD 140
++ P FS T T+ + E+ P S+ +VTATDE LN
Sbjct: 2064 DNR-----PTFSPATLTVHLLENCPPGFSVLQVTATDE----DSGLN------------- 2101
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPS 200
GE++ R++A +D F + TG I + +D
Sbjct: 2102 ----------GELVYRIEAGAQDR--------------FLIHLVTGVIR-VGNATIDR-E 2135
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVI---VRVSRIN 257
+ Y L ATD G TV P+S G AI+T++ + SR
Sbjct: 2136 EQESYRLTVVATDRG--------TV-------PLS-------GTAIVTILIDDINDSRPE 2173
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNL---------GT 308
LNPI T SV E++ T++ +T D D +EY +VG
Sbjct: 2174 FLNPIQ-----TVSVLESAEPGTVIANITAIDHDLN-PKLEYHIVGIVAKDDTDRLVPNQ 2227
Query: 309 PPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRS---GTAQVTIS 365
F + +TG + + +NRE+ + Y++ + V D +D L +RS A++T++
Sbjct: 2228 EDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASD-----LPERSVSVPNAKLTVN 2282
Query: 366 VLNMNDEPPVCNP 378
VL++ND P P
Sbjct: 2283 VLDVNDNTPQFKP 2295
Score = 56.2 bits (134), Expect = 7e-08
Identities = 72/254 (28%), Positives = 116/254 (45%), Gaps = 50/254 (19%)
Query: 142 INVTEKKSVGEIIARVKATDRDE--DSSIIYSF-----KTQQKMFCLDPFTGTITLLQPL 194
+++ E+ + + V ATD+DE + ++ YSF + F +DP +G I Q L
Sbjct: 2620 LHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRL 2679
Query: 195 NLDNPSNSKIYSLETEATDNGNNTSSYTFT---VFVENVDDPISCDPSFSTGAAIITVIV 251
+ ++ + +YSL A+D G T V +E++DD +P F V
Sbjct: 2680 DRESQA---VYSLILVASDLGQPVPYETMQPLQVALEDIDDN---EPLF----------V 2723
Query: 252 RVSRINELNPIGSASAFTFSVFENSPVDTLVGKVT-FTDAD-WPFNNMEYTVVGGNLGTP 309
R P GS +V E+SP TLVG VT DAD P + Y + GN
Sbjct: 2724 RP-------PKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGN--EE 2774
Query: 310 PKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGT---------A 360
F+++PD G + +L L+RE E+ + VK + ++ P R S T
Sbjct: 2775 KNFHLQPD-GCLLVLRDLDREREAIFSFIVKAS---SNRSWTPPRGPSPTLDLVADLTLQ 2830
Query: 361 QVTISVLNMNDEPP 374
+V + + ++ND+PP
Sbjct: 2831 EVRVVLEDINDQPP 2844
Score = 55.8 bits (133), Expect = 9e-08
Identities = 70/280 (25%), Positives = 108/280 (38%), Gaps = 36/280 (12%)
Query: 142 INVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNP 199
IN+ E + V A D D E+ +++YS + K + L+ TG I +
Sbjct: 785 INLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAM----- 839
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
L+ E D V V + P P +T +A TV V + +N+
Sbjct: 840 -------LDRENPDPHEAELMRKIVVSVTDCGRP----PLKATSSA--TVFVNLLDLNDN 886
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGNLGTPPK-FYIEPD 317
+P F V E P + +V D D N + Y + +G P F I
Sbjct: 887 DPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMP---VGMPRMDFLINSS 943
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
+GV+ L+RE ++Y++ V +D +S T+ +TI VL++NDE P
Sbjct: 944 SGVVVTTTELDRERIAEYQLRVVASDAGTPT-------KSSTSTLTIHVLDVNDETPTFF 996
Query: 378 PPHLETQIYSTV-ESFHSAQLFSKDSP---QEHLSYSIVG 413
P + V F L D+ LSY I G
Sbjct: 997 PAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITG 1036
Score = 53.1 bits (126), Expect = 6e-07
Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 50/249 (20%)
Query: 144 VTEKKSVGEIIARVKATDRDEDSSII-YSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNS 202
++E VG + ++ A D D D + S + + F ++P TG + L QPL+ + S
Sbjct: 42 ISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSE- 100
Query: 203 KIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPI 262
+++E +D+ G V ++V +N+ P
Sbjct: 101 --FTVEFSVSDH---------------------------QGVITRKVNIQVGDVNDNAPT 131
Query: 263 GSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNL---GTPPK--FYIEPD 317
++ + EN+PV T + V TD D GG++ PP F I+
Sbjct: 132 FHNQPYSVRIPENTPVGTPIFIVNATDPD--------LGAGGSVLYSFQPPSQFFAIDSA 183
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
G++ ++ L+ E Y++ V TD D R S A + I + ++ D P+
Sbjct: 184 RGIVTVIRELDYETTQAYQLTVNATD------QDKTRPLSTLANLAIIITDVQDMDPIFI 237
Query: 378 PPHLETQIY 386
T IY
Sbjct: 238 NLPYSTNIY 246
Score = 48.5 bits (114), Expect = 1e-05
Identities = 66/250 (26%), Positives = 102/250 (40%), Gaps = 48/250 (19%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDED-----SSIIYSFKTQQKMFCLDPFTGTITLLQ 192
P ++V E G + + ATD D SIIYS + + F ++ +G IT
Sbjct: 674 PAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQ-FRINARSGEITTTS 732
Query: 193 PLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVR 252
L+ + S Y L A D G + T I TV +
Sbjct: 733 LLDRETKSE---YILIVRAVDGGVGHNQKT----------------------GIATVNIT 767
Query: 253 VSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKF 312
+ IN+ +P + + ++ E +P D+ V V D D N T+V ++ P KF
Sbjct: 768 LLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENG---TLV-YSIQPPNKF 823
Query: 313 Y-IEPDTGVIK----LLDSLN---REIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
Y + TG I+ +LD N E E KI V VTD P + + +A V +
Sbjct: 824 YSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGR-----PPLKATSSATVFV 878
Query: 365 SVLNMNDEPP 374
++L++ND P
Sbjct: 879 NLLDLNDNDP 888
Score = 48.1 bits (113), Expect = 2e-05
Identities = 56/254 (22%), Positives = 104/254 (40%), Gaps = 41/254 (16%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSFK----TQQKMFCLDPFTGTITLLQPLNL 196
+I ++E V +A V A+D D + +F +++ F ++ TG +T+ +PL+
Sbjct: 1857 NITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDR 1916
Query: 197 DNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
+ Y L DN N + D + +++ +S
Sbjct: 1917 ERIPE---YKLTISVKDNPENPR-------IARRDYDL--------------LLIFLSDE 1952
Query: 257 NELNPIGSASAFTFSVFENSPVDT----LVGKVTFTDADWP-FNNMEYTVVGGNLGTPPK 311
N+ +P+ + S + V ENSP T L G + DAD + + Y ++G G
Sbjct: 1953 NDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGL--- 2009
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F I TGV+ + + + E A L+ + + + + TA + I++L+ ND
Sbjct: 2010 FDINSSTGVVTVRSGVIIDRE-----AFSPPILELLLLAEDIGLLNSTAHLLITILDDND 2064
Query: 372 EPPVCNPPHLETQI 385
P +P L +
Sbjct: 2065 NRPTFSPATLTVHL 2078
Score = 45.4 bits (106), Expect = 1e-04
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 16/127 (12%)
Query: 251 VRVSRINELN--PIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLG 307
V+++ INE + PI S + S++EN V T V V TD D F + Y
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFF----SD 501
Query: 308 TPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVL 367
P +F ++ DTG+I L+ L+ E+ ++ + + D + T +V I+VL
Sbjct: 502 DPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGE---------ETTGRVRINVL 552
Query: 368 NMNDEPP 374
++ND P
Sbjct: 553 DVNDNVP 559
Score = 43.9 bits (102), Expect = 3e-04
Identities = 62/255 (24%), Positives = 103/255 (40%), Gaps = 53/255 (20%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDE--DSSIIYSFKTQQ-KMFCLDPFTGTITLLQPL 194
P S +V E + G + + ATD+DE + + YS + + F +D +G +T +PL
Sbjct: 2512 PQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPL 2571
Query: 195 NLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVD----DPISCDPSFSTGAAIITVI 250
+ + +SL ATD G T + VE +D P+ P T
Sbjct: 2572 Q-----SYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGT-------- 2618
Query: 251 VRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFT------DADWPFNNMEYTVVGG 304
+ I E P+ S + V+ + L G V ++ + DW F
Sbjct: 2619 --ILHIREEIPLRSN---VYEVYATDKDEGLNGAVRYSFLKTAGNRDWEF---------- 2663
Query: 305 NLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
F I+P +G+I+ L+RE ++ Y + + +DL +P Q QV +
Sbjct: 2664 -------FIIDPISGLIQTAQRLDRESQAVYSLILVASDL-GQPVPYETMQ---PLQVAL 2712
Query: 365 SVLNMNDEPPVCNPP 379
++ N EP PP
Sbjct: 2713 EDIDDN-EPLFVRPP 2726
Score = 43.5 bits (101), Expect = 4e-04
Identities = 76/335 (22%), Positives = 132/335 (39%), Gaps = 62/335 (18%)
Query: 95 TATLEIDEDYPLFQSIYRV--TATDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGE 152
T T+ D+ P S +V T DE N R + D ++++ E VG+
Sbjct: 1386 TLTVVADDGGPKVDSTVKVYITVLDEN-DNSPRFDFTSD--------SAVSIPEDCPVGQ 1436
Query: 153 IIARVKATDRDEDSS--IIYSFKTQQKMFCLDPFT-----GTITLLQPLNLDNPSNSKIY 205
+A VKA D D S+ +++S + + T G + + +PL+ + + Y
Sbjct: 1437 RVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDH---Y 1493
Query: 206 SLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNP-IGS 264
L+ A+D G + V +D IN+ P I S
Sbjct: 1494 ILQVVASDRGTPPRKKDHILQVTILD------------------------INDNPPVIES 1529
Query: 265 ASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIEPDTGVIKL 323
+ SV EN T V +V TD D N+ + Y + GN F ++ +G I
Sbjct: 1530 PFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMA--FRMDRISGEIAT 1587
Query: 324 LDSL-NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLE 382
+ +RE +S Y + V D + S T V +++++ ND P+ PH E
Sbjct: 1588 RPAPPDRERQSFYHLVATVEDEGTPTL-------SATTHVYVTIVDENDNAPMFQQPHYE 1640
Query: 383 TQIYSTVESFHSA-----QLFSKDSPQEHLSYSIV 412
+ ++ +++ L + P ++Y+IV
Sbjct: 1641 VLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIV 1675
Score = 43.1 bits (100), Expect = 6e-04
Identities = 87/379 (22%), Positives = 147/379 (38%), Gaps = 76/379 (20%)
Query: 70 HVLTINIIDVPESP---------NCTADPKFSSGTATLEI---DEDYPL--FQSIYRVTA 115
H+L + I+D+ ++P N + + GTA +++ D D + S Y
Sbjct: 1511 HILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEG 1570
Query: 116 TDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKT- 174
++ DR + G+ RP P D E++S ++A V+ S+ + + T
Sbjct: 1571 NKDMAFRMDR--ISGEIATRPAPPD----RERQSFYHLVATVEDEGTPTLSATTHVYVTI 1624
Query: 175 ----------QQKMFCL------DPFTGTITLLQPLNLD-NPSNSKIYSLE--------- 208
QQ + + D ++ +Q L+LD P+ + Y++
Sbjct: 1625 VDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFR 1684
Query: 209 --------TEATDNGNNTSSYTFTVFVENVDD-PISCDPSFSTGAAIITVIVRVSRINEL 259
T A + S +T+ V D PI ST TV+V V+ IN+
Sbjct: 1685 IDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTST----TTVLVNVNDINDN 1740
Query: 260 NPIGSAS-AFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGN-LGTPPKFYIEPD 317
P F V E P + + P +EY+++ G+ LG +F I P
Sbjct: 1741 VPTFPRDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLG---EFVISPV 1797
Query: 318 TGVIKLLD--SLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
GV+++ L+RE + Y + + D + S T V I VL++ND PV
Sbjct: 1798 EGVLRVRKDVELDRETIAFYNLTICARDRGMPPL-------SSTMLVGIRVLDINDNDPV 1850
Query: 376 C--NPPHLETQIYSTVESF 392
P ++ S V SF
Sbjct: 1851 LLNLPMNITISENSPVSSF 1869
Score = 42.7 bits (99), Expect = 8e-04
Identities = 50/269 (18%), Positives = 100/269 (37%), Gaps = 47/269 (17%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSF-------------KTQQKMFCLDPF 184
P+ +++V E G +IA + A D D + + Y Q+ F ++
Sbjct: 2177 PIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNIN 2236
Query: 185 TGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGA 244
TG++ + P+N + + Y + DN ++ P S
Sbjct: 2237 TGSVMVKSPMNRELVAT---YEVTLSVIDNASDL-------------------PERSVSV 2274
Query: 245 AIITVIVRVSRINELNPIGSASAFTF---SVFENSPVDTLVGKVTFTDADWPFNNM-EYT 300
+ V V +N+ P T+ + E + T + V D D N + YT
Sbjct: 2275 PNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYT 2334
Query: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTA 360
++ PP + D+ K++ + + E + + V DN + P R+
Sbjct: 2335 LLD---LVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPP-----RAAEI 2386
Query: 361 QVTISVLNMNDEPPVCNPPHLETQIYSTV 389
V + ++++ND P+ + P + ++ V
Sbjct: 2387 PVYLEIVDINDNNPIFDQPSYQEAVFEDV 2415
Score = 38.5 bits (88), Expect = 0.014
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 247 ITVIVRVSRINELNPIGSASAFT-FSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGG 304
+ VIV V IN+ P+ + ++ + E + + T V V TD D + Y ++ G
Sbjct: 1192 VRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSG 1251
Query: 305 NLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
G KF I+ TG+I ++ L+ E ++ Y + V TD P Q G V I
Sbjct: 1252 AEG---KFEIDESTGLIITVNYLDYETKTSYMMNVSATDQ-----APPFNQ--GFCSVYI 1301
Query: 365 SVLNMNDE 372
++LN DE
Sbjct: 1302 TLLNELDE 1309
Score = 38.1 bits (87), Expect = 0.019
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 21/117 (17%)
Query: 272 VFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY-IEPDTGVIKLLDSLNRE 330
+ E++PV + V ++ D D + V G + +F+ +EPDTGV+ L L+RE
Sbjct: 42 ISEDTPVGSSVTQLLAQDMD-----NDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRE 96
Query: 331 IESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYS 387
+S++ + V+D Q T +V I V ++ND N P Q YS
Sbjct: 97 TKSEFTVEFSVSD----------HQGVITRKVNIQVGDVND-----NAPTFHNQPYS 138
Score = 36.2 bits (82), Expect = 0.071
Identities = 54/238 (22%), Positives = 96/238 (40%), Gaps = 42/238 (17%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSSIIYSFKT---QQKMFCLDPFTGTITLLQPLNLDN 198
+ + E +G + V+ATDRD + +++ + F +D TG I + L+ +
Sbjct: 1216 LGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVNYLDYET 1275
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
++ Y + ATD P F+ G + I ++ ++E
Sbjct: 1276 KTS---YMMNVSATDQA----------------------PPFNQGFCSV-YITLLNELDE 1309
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPK--FYIEP 316
+AS + ++ EN + T + +V D N + Y T K F I+
Sbjct: 1310 AVQFSNAS-YEAAILENLALGTEIVRVQAYSID-NLNQITYR-FNAYTSTQAKALFKIDA 1366
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
TGVI + ++RE Y + V + +D P + T +V I+VL+ ND P
Sbjct: 1367 ITGVITVQGLVDREKGDFYTLTV----VADDGGP----KVDSTVKVYITVLDENDNSP 1416
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 77.8 bits (190), Expect = 2e-14
Identities = 90/332 (27%), Positives = 143/332 (43%), Gaps = 50/332 (15%)
Query: 141 SINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
S++V E + +G I + A+D D E++ I Y + F +D +G ITL PL+ +
Sbjct: 864 SVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYE- 922
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
+ Y+L A DNG P D ++ V V V+ +N+
Sbjct: 923 --DQVTYTLAITARDNG----------------IPQKADTTY--------VEVMVNDVND 956
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPD 317
P AS +T V E++P T V +++ TD D N ++YT G G F IEP
Sbjct: 957 NAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDG-DGDFTIEPT 1015
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
+G+++ + L+RE S Y++ D +P PLR + + V ++ND PV
Sbjct: 1016 SGIVRTVRRLDREAVSVYELTAYAVD---RGVP-PLRT---PVSIQVMVQDVNDNAPVFP 1068
Query: 378 PPHLETQI-YSTVESFHSAQLFSKD---SPQEHLSYSIVGEQDESRKKRLEKMSLSSYYF 433
E ++ +++ AQ+ + D P H+ Y IV E L +M + F
Sbjct: 1069 AEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIV----EGNIPELFQMDI----F 1120
Query: 434 KKCFTDVIRADNHNNDYFPSVTNITRANQVSR 465
T +I D + V T A VSR
Sbjct: 1121 SGELTALIDLDYEARQEYVIVVQATSAPLVSR 1152
Score = 71.2 bits (173), Expect = 2e-12
Identities = 77/275 (28%), Positives = 120/275 (43%), Gaps = 44/275 (16%)
Query: 153 IIARVKATDRDEDSSIIYSFK----TQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLE 208
++ RV ATDRD+D++ + + + F +D TG I ++ PL+ + + Y+L
Sbjct: 563 VVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEA---EREYALR 619
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
A D G P+S + TG A I V+ IN+ PI ++ F
Sbjct: 620 IRAQDAGR---------------PPLSNN----TGLASIQVV----DINDHIPIFVSTPF 656
Query: 269 TFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSL 327
SV EN+P+ V + DAD N +EY++ G TP F I TG + + L
Sbjct: 657 QVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTP--FVINSATGWVSVSGPL 714
Query: 328 NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP--VCNPPHLETQI 385
+RE Y V+ D + + S +A VT++VL++ND P HL
Sbjct: 715 DRESVEHYFFGVEARDHGSPPL-------SASASVTVTVLDVNDNRPEFTMKEYHLRLNE 767
Query: 386 YSTV-ESFHSAQLFSKDSPQEHLSYSIVGEQDESR 419
+ V S S +D+ +SY I G +R
Sbjct: 768 DAAVGTSVVSVTAVDRDA-NSAISYQITGGNTRNR 801
Score = 59.3 bits (142), Expect = 8e-09
Identities = 60/230 (26%), Positives = 103/230 (44%), Gaps = 45/230 (19%)
Query: 154 IARVKATDRDEDSS--IIYSFKTQQKM---FCLDPFTGTITLLQPLNLDNPSNSKIYSLE 208
+ ++ ATDRD ++ + Y+F+ + F ++P +G + ++ L+ + S +Y L
Sbjct: 980 VLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVS---VYELT 1036
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
A D G V + P+S + V V +N+ P+ A F
Sbjct: 1037 AYAVDRG-----------VPPLRTPVS-------------IQVMVQDVNDNAPVFPAEEF 1072
Query: 269 TFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSL 327
V ENS V ++V ++T D D P ++ Y +V GN+ P F ++ +G + L L
Sbjct: 1073 EVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNI--PELFQMDIFSGELTALIDL 1130
Query: 328 NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
+ E +Y I V+ T PL R A V + +++ ND PV N
Sbjct: 1131 DYEARQEYVIVVQATSA-------PLVSR---ATVHVRLVDQNDNSPVLN 1170
Score = 57.8 bits (138), Expect = 2e-08
Identities = 65/257 (25%), Positives = 104/257 (40%), Gaps = 43/257 (16%)
Query: 144 VTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQ-----KMFCLDPFTGTITLLQPLNL 196
V E ++ G + RV A D D E ++YS ++F +DP +G I L
Sbjct: 334 VPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTAAAL-- 391
Query: 197 DNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
D S + Y L A D+G+ S T V V V+
Sbjct: 392 DRESMERHY-LRVTAQDHGSPRLSAT------------------------TMVAVTVADR 426
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVG---GNLGTPPKF 312
N+ +P+ + + ++ EN + ++ TD D P N N+ Y VG F
Sbjct: 427 NDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAF 486
Query: 313 YIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDE 372
I+P +G+I ++RE Y++ V+ +D + P RS T +V I+VL+ ND
Sbjct: 487 EIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGP-----RSATVRVHITVLDENDN 541
Query: 373 PPVCNPPHLETQIYSTV 389
P + Q+ V
Sbjct: 542 APQFSEKRYVAQVREDV 558
Score = 52.8 bits (125), Expect = 7e-07
Identities = 59/269 (21%), Positives = 104/269 (38%), Gaps = 44/269 (16%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSSIIYSFK--TQQKMFCLDPF--TGTITLLQPLNLD 197
+ + E +VG + V A DRD +S+I Y + F + G +TL PL+
Sbjct: 763 LRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDY- 821
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
+ + L A+D + Y V + ++ N
Sbjct: 822 --KQERYFKLVLTASDRALHDHCY---------------------------VHINITDAN 852
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPD 317
P+ ++ ++ SV E+ P+ + + ++ +D D N ++ NL P+F I+ D
Sbjct: 853 THRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNL---PQFRIDAD 909
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
+G I L L+ E + Y +A+ D + IP Q++ T V + V ++ND P
Sbjct: 910 SGAITLQAPLDYEDQVTYTLAITARD---NGIP----QKADTTYVEVMVNDVNDNAPQFV 962
Query: 378 PPHLETQIYSTVESFHSAQLFSKDSPQEH 406
H + F S S H
Sbjct: 963 ASHYTGLVSEDAPPFTSVLQISATDRDAH 991
Score = 52.4 bits (124), Expect = 1e-06
Identities = 70/282 (24%), Positives = 116/282 (41%), Gaps = 47/282 (16%)
Query: 146 EKKSVGEIIARVKATDRDE--DSSIIYSF-------KTQQKMFCLDPFTGTITLLQPLNL 196
E G I +++ATD D ++++ Y F F +DP +G I+ ++
Sbjct: 444 ENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVDR 503
Query: 197 DNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
++ + Y L EA+D G + TV V ITV+
Sbjct: 504 EHMES---YELVVEASDQGQEPGPRSATVRVH------------------ITVLDE---- 538
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGNLGTPPKFYIE 315
N+ P S + V E+ T+V +VT TD D N + Y ++ GN + F I+
Sbjct: 539 NDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGN--SRGHFAID 596
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
TG I+++ L+ E E +Y + ++ DA PL +G A +I V+++ND P+
Sbjct: 597 SLTGEIQVVAPLDFEAEREYALRIRA----QDAGRPPLSNNTGLA--SIQVVDINDHIPI 650
Query: 376 CNPPHLETQIYSTVESFHSA---QLFSKDSPQE-HLSYSIVG 413
+ + HS Q D + L YS+ G
Sbjct: 651 FVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTG 692
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 77.4 bits (189), Expect = 3e-14
Identities = 79/291 (27%), Positives = 130/291 (44%), Gaps = 44/291 (15%)
Query: 94 GTATLEIDEDYPLF-QSIYRVTATDEVFANGDRL--NVGGDHCARPFPLDS---INVTEK 147
G +L + DY L Q + VTA+D + ++ NV + RP S +NV E
Sbjct: 665 GLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNED 724
Query: 148 KSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIY 205
+ G + + ATD D E++ I Y + F +D TG +T L+ ++ + Y
Sbjct: 725 RPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYEDQVS---Y 781
Query: 206 SLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSA 265
+L A DNG S T ++E + V+ +N+ P
Sbjct: 782 TLAITARDNGIPQKSDT--TYLE----------------------ILVNDVNDNAPQFLR 817
Query: 266 SAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIEPDTGVIKLL 324
++ SV+E+ P T V +++ TD D N + YT GG+ G F +E +G+++ L
Sbjct: 818 DSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGD-FIVESTSGIVRTL 876
Query: 325 DSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
L+RE +QY + D P+ +VT++VL++ND PPV
Sbjct: 877 RRLDRENVAQYVLRAYAVDKGMPPARTPM-------EVTVTVLDVNDNPPV 920
Score = 71.6 bits (174), Expect = 2e-12
Identities = 67/249 (26%), Positives = 109/249 (43%), Gaps = 40/249 (16%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQ----QKMFCLDPFTGTITLLQPLNLD 197
+ V E + G + RV A+DRD+ S+ + + + F LD TG + ++ PL+ +
Sbjct: 406 VQVREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYE 465
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
+K Y+L A D G P S + ++TV +V IN
Sbjct: 466 T---TKEYTLRVRAQDGGR---------------------PPLSNVSGLVTV--QVLDIN 499
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEP 316
+ PI ++ F +V E+ P+ LV V DAD N +EY + G +G F I
Sbjct: 500 DNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAG--VGHDFPFTINN 557
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVC 376
TG I + L+RE Y V+ D A+ + +A V+++VL++ND P
Sbjct: 558 GTGWISVAAELDREEVDFYSFGVEARDHGTPAL-------TASASVSVTVLDVNDNNPTF 610
Query: 377 NPPHLETQI 385
P ++
Sbjct: 611 TQPEYTVRL 619
Score = 70.5 bits (171), Expect = 3e-12
Identities = 69/262 (26%), Positives = 112/262 (42%), Gaps = 43/262 (16%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSS--------IIYSFKTQQKMFCLDPFTGTIT 189
P V E + G +A ++A D DE + ++ ++ Q F LDP TG +T
Sbjct: 184 PSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQ-FFSLDPVTGAVT 242
Query: 190 LLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITV 249
+ L+ + S + A D+G S A+ T+
Sbjct: 243 TAEELDRETKST---HVFRVTAQDHGMPRRS------------------------ALATL 275
Query: 250 IVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGT 308
+ V+ N+ +P+ + S+ EN V V V TD D P N N+ Y ++ G+ G+
Sbjct: 276 TILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGS 335
Query: 309 PPK-FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVL 367
P + F I+P +GVI+ ++RE Y++ V+ +D D P RS TA V +SV
Sbjct: 336 PSEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGP-----RSTTAAVFLSVE 390
Query: 368 NMNDEPPVCNPPHLETQIYSTV 389
+ ND P + Q+ V
Sbjct: 391 DDNDNAPQFSEKRYVVQVREDV 412
Score = 60.5 bits (145), Expect = 4e-09
Identities = 87/379 (22%), Positives = 152/379 (40%), Gaps = 59/379 (15%)
Query: 38 AGSGVITATKIFNYETDPIRFLLIV--DTGRLYRHVLTINIIDVPESPNCTADPKFSSGT 95
+G G+++ +Y+ + L + D R + +N+ D T P F S
Sbjct: 662 SGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDAN-----THRPVFQSSH 716
Query: 96 ATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSIN--VTEKKSVG-- 151
T+ ++ED P ++ ++ATDE R+ + F +D+ VT + +
Sbjct: 717 YTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYE 776
Query: 152 -------EIIARVKATDRDEDSS----IIYSFKTQQKMFCLDPFTGTI--------TLLQ 192
I AR + D++ ++ F D + G++ ++LQ
Sbjct: 777 DQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQ 836
Query: 193 PLNLDNPS--NSKIYSLETEATDNGN------NTSSYTFTVFV---ENVDDPI----SCD 237
D S N +++ + D+G+ +TS T+ ENV + + D
Sbjct: 837 ISATDRDSGLNGRVF-YTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVD 895
Query: 238 PSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-N 296
+ V V V +N+ P+ F V ENSP+ V +VT TD D N
Sbjct: 896 KGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQ 955
Query: 297 MEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQR 356
+ Y +V GN+ P F ++ +G + L L+ E +Y + ++ T PL R
Sbjct: 956 IMYQIVEGNI--PEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSA-------PLVSR 1006
Query: 357 SGTAQVTISVLNMNDEPPV 375
A V + +L+ ND PPV
Sbjct: 1007 ---ATVHVRLLDRNDNPPV 1022
Score = 56.6 bits (135), Expect = 5e-08
Identities = 62/261 (23%), Positives = 104/261 (39%), Gaps = 44/261 (16%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKT--QQKMFCLDPFT--GTITLLQP 193
P ++ + E +VG + V A DRD S I Y + + F + + G ++L P
Sbjct: 613 PEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALP 672
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
L+ Y LE + ++ S T ++V V
Sbjct: 673 LD---------YKLERQYV---------------------LAVTASDGTRQDTAQIVVNV 702
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY 313
+ N P+ +S +T +V E+ P T V ++ TD D N + ++ P+F
Sbjct: 703 TDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSI---PQFR 759
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
I+ DTG + L+ E + Y +A+ D + IP Q+S T + I V ++ND
Sbjct: 760 IDADTGAVTTQAELDYEDQVSYTLAITARD---NGIP----QKSDTTYLEILVNDVNDNA 812
Query: 374 PVCNPPHLETQIYSTVESFHS 394
P + +Y V F S
Sbjct: 813 PQFLRDSYQGSVYEDVPPFTS 833
Score = 50.8 bits (120), Expect = 3e-06
Identities = 55/246 (22%), Positives = 96/246 (39%), Gaps = 42/246 (17%)
Query: 144 VTEKKSVGEIIARVKATDRDEDSSIIYSFKT----QQKMFCLDPFTGTITLLQPLNLDNP 199
V E +G ++ V+A D D + ++ F ++ TG I++ L+ +
Sbjct: 514 VLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEV 573
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
YS EA D+G P+ + A+ V V V +N+
Sbjct: 574 D---FYSFGVEARDHGT---------------------PALTASAS---VSVTVLDVNDN 606
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTG 319
NP + +T + E++ V T V V+ D D + + Y + GN + G
Sbjct: 607 NPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRD-AHSVITYQITSGNTRNRFSITSQSGGG 665
Query: 320 VIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPP 379
++ L L+ ++E QY +AV +D R TAQ+ ++V + N PV
Sbjct: 666 LVSLALPLDYKLERQYVLAVTASD----------GTRQDTAQIVVNVTDANTHRPVFQSS 715
Query: 380 HLETQI 385
H +
Sbjct: 716 HYTVNV 721
Score = 30.0 bits (66), Expect = 5.1
Identities = 26/126 (20%), Positives = 52/126 (41%), Gaps = 29/126 (23%)
Query: 72 LTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATD-------------- 117
+T+ ++DV ++P P F + ++E+ P+ ++ RVTATD
Sbjct: 907 VTVTVLDVNDNP-----PVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIV 961
Query: 118 ----------EVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSS 167
++F+ V D+ RP + I T V V+ DR+++
Sbjct: 962 EGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPP 1021
Query: 168 IIYSFK 173
++ +F+
Sbjct: 1022 VLGNFE 1027
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 72.8 bits (177), Expect = 7e-13
Identities = 78/278 (28%), Positives = 119/278 (42%), Gaps = 47/278 (16%)
Query: 108 QSIY--RVTATDEVFANGDRLNVGGDHCARPFPL-DSINVT----EKKSVGEIIARVKAT 160
Q IY +TATD +F + V P+ D + T E +II +V A
Sbjct: 2995 QDIYFLNITATDGLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAK 3054
Query: 161 DRDEDSS--IIYS-FKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNN 217
D D S+ I YS + + F LDP +G + L L+ + +YSL +ATD G
Sbjct: 3055 DADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRER---IPVYSLMAKATDGGGR 3111
Query: 218 TSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSP 277
+ +E+V+D +P P+ S+ + V+EN+
Sbjct: 3112 FCQSNIHLILEDVND----NP----------------------PVFSSDHYNTCVYENTA 3145
Query: 278 VDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKI 337
L+ +V D D N + + G F I+ +G+I L L+RE +S Y I
Sbjct: 3146 TKALLTRVQAVDPDIGINRKVVYSLADSAGGV--FSIDSSSGIIILEQPLDREQQSSYNI 3203
Query: 338 AVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
+V+ TD P + S VTI+VL++ND PPV
Sbjct: 3204 SVRATD------QSPGQSLSSLTTVTITVLDINDNPPV 3235
Score = 63.5 bits (153), Expect = 4e-10
Identities = 54/210 (25%), Positives = 96/210 (45%), Gaps = 39/210 (18%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSS--IIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
S+N+ E +G I +V+A D+D S+ + YS T + F ++ TG + + L+ ++
Sbjct: 837 SVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYVADQLDRES 896
Query: 199 PSNSKIYSLETEATDNGNNT----SSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVS 254
+N YSL+ EA D + S T VF+++V+D C P+F
Sbjct: 897 KAN---YSLKIEARDKAESGQQLFSVVTLKVFLDDVND---CSPAFIP------------ 938
Query: 255 RINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPF-NNMEYTVVGGNLGTPPKFY 313
S+++ V E+ PV T++ + D D + Y++V G +F
Sbjct: 939 -----------SSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNG---RFE 984
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTD 343
I+ +G I+L L+ E + Y + V+ D
Sbjct: 985 IDKASGAIRLSKELDYEKQQFYNLTVRAKD 1014
Score = 62.4 bits (150), Expect = 9e-10
Identities = 61/235 (25%), Positives = 104/235 (44%), Gaps = 40/235 (17%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKM-FCLDPFTGTITLLQPL 194
PL V E VG + V A+D+D E+ I YS + + F ++ FTG I+ + L
Sbjct: 475 PLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLPFVINQFTGVISTTEEL 534
Query: 195 NLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVS 254
+ + S+ +IY A+D G S Y + + V +R+
Sbjct: 535 DFE--SSPEIYRFIVRASDWG---SPYRHE--------------------SEVNVTIRIG 569
Query: 255 RINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGN-LGTPPKFY 313
+N+ +P+ A + + PV + V+ D D ++Y ++ GN LG FY
Sbjct: 570 NVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDID-ELELVKYKIISGNELGF---FY 625
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLN 368
+ PD+GV++L SL A+++T D + + DP+ + ISVL+
Sbjct: 626 LNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPM-------SINISVLH 673
Score = 62.0 bits (149), Expect = 1e-09
Identities = 79/313 (25%), Positives = 129/313 (41%), Gaps = 65/313 (20%)
Query: 144 VTEKKSVGEIIARVKATDRDE--DSSIIYSFKTQQK-MFCLDPFTGTITLLQPLNLDNPS 200
V E + ++ RV+A D D + ++YS +F +D +G I L QPL+ + S
Sbjct: 3140 VYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQS 3199
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
+ Y++ ATD S + T TV + V IN+
Sbjct: 3200 S---YNISVRATDQSPGQSLSSLT-----------------------TVTITVLDINDNP 3233
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPDTG 319
P+ + +V E++ T V V T D N + Y + GN KF I P TG
Sbjct: 3234 PVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGN--EQGKFKINPKTG 3291
Query: 320 VIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPP 379
I + + L+ E+ ++ + V+ D A+ S A V I++ ++ND NPP
Sbjct: 3292 GISVSEVLDYELCKRFYLVVEAKDGGTPAL-------SAVATVNINLTDVND-----NPP 3339
Query: 380 HLETQIYSTVESFHS------AQLFSKD---SPQEHLSYSIV-GEQDE-----------S 418
+YS V S + L ++D P + +SIV G++D
Sbjct: 3340 KFSQDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVK 3399
Query: 419 RKKRLEKMSLSSY 431
KK+L++ +S Y
Sbjct: 3400 VKKKLDRERVSGY 3412
Score = 61.2 bits (147), Expect = 2e-09
Identities = 70/280 (25%), Positives = 114/280 (40%), Gaps = 43/280 (15%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQ-----QKMFCLDPFTGTITLLQ 192
P + ++E I +++ATDRDE + Y+ + + F +DP TG + +
Sbjct: 1463 PNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAE 1522
Query: 193 PLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVR 252
L+ EA D + + V D F + VIV
Sbjct: 1523 -------------RLDHEAQDK------HILNIMVR--------DQEFPYRRNLARVIVN 1555
Query: 253 VSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPK 311
V N+ +P + + SVFE++ + + V +VT D D N + YT+ GN G
Sbjct: 1556 VEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGN--M 1613
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F IEP G+I + + Q+ +++KVTD + + S TA V ISV ++
Sbjct: 1614 FKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPM-------SATAIVRISVTMSDN 1666
Query: 372 EPPVCNPPHLETQIYSTVESFHSAQLFSKDSPQEHLSYSI 411
P + ++ V+ S L S S Q L Y +
Sbjct: 1667 SHPKFIHKDYQAEVNENVDIGTSVILISAIS-QSTLIYEV 1705
Score = 58.9 bits (141), Expect = 1e-08
Identities = 61/240 (25%), Positives = 107/240 (44%), Gaps = 48/240 (20%)
Query: 151 GEIIARVKATDRDE--DSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLE 208
G +I +V A D+D+ + + Y + F ++P +G + L + N D SN + Y +
Sbjct: 2100 GTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSGNVILKEAFNSDL-SNIE-YGVT 2157
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
A D G PS ST + IV N+ P+ +
Sbjct: 2158 ILAKDGGK---------------------PSLSTSVELPITIV-----NKAMPVFDKPFY 2191
Query: 269 TFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPK-FYIEPDTGVIKLLDSL 327
T SV E+ ++T + + T + + Y ++ G+ P K F I+ DTGV+K++ L
Sbjct: 2192 TASVNEDIRMNTPILSINATSPEG--QGIIYIIIDGD---PFKQFNIDFDTGVLKVVSPL 2246
Query: 328 NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVL--NMNDEPPVCNPPHLETQI 385
+ E+ S YK+ ++ +D A A+VT+ +L ++ND PP+ + P T +
Sbjct: 2247 DYEVTSAYKLTIRASDALTGA----------RAEVTVDLLVNDVNDNPPIFDQPTYNTTL 2296
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/406 (24%), Positives = 153/406 (37%), Gaps = 87/406 (21%)
Query: 40 SGVITATKIFNYETDPIRFL-------LIVDTGRLYRHVLTINIIDVPESPNCTADPKFS 92
SGVIT + +P+ L L T +++ VL N+ P FS
Sbjct: 2448 SGVITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYS----------PAFS 2497
Query: 93 SGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVG--GDHCARPFPLDS---INVTEK 147
T E+ E+ + V ATD +++ D F +DS + TE+
Sbjct: 2498 QSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVITTER 2557
Query: 148 KS-----VGEIIARVKATDRD-------------EDSSIIYSFKTQQKMFCLDPFTGT-- 187
G++ V+A D +++ F T + + G
Sbjct: 2558 LDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGH 2617
Query: 188 -ITLLQPLNLDNPSNSKI-YSLETEAT-----------DNG--------NNTSSYTFTVF 226
+T +Q ++ D+ +NS+I YSL +EA+ DNG N + + F
Sbjct: 2618 LVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFF 2677
Query: 227 VENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVT 286
V+ VD I S +I V + V P + S ++F++ E DT +G
Sbjct: 2678 VKAVDGGIPVKHS------LIPVYIHVLPPETFLPSFTQSQYSFTIAE----DTAIGSTV 2727
Query: 287 FTDADWPFNNMEYTVVGGNLGTPPK---FYIEPDTGVIKLLDSLNREIESQYKIAVKVTD 343
T P N+ ++ V G K F IE +TG IKL L+RE + V T
Sbjct: 2728 DTLRILPSQNVWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAAT- 2786
Query: 344 LDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYSTV 389
IP T V I VL++ND PV ET Y T+
Sbjct: 2787 -----IPLDKVDIVFTVDVDIKVLDLNDNKPV-----FETSSYDTI 2822
Score = 55.8 bits (133), Expect = 9e-08
Identities = 41/140 (29%), Positives = 72/140 (51%), Gaps = 15/140 (10%)
Query: 249 VIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVG-GNL 306
V V VS +N+ +P+ A+T + E+ P + ++ KV+ DAD N + Y++ G GN
Sbjct: 3015 VEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGN- 3073
Query: 307 GTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISV 366
+F+++P++G +K L L+RE Y + K TD R + + + +
Sbjct: 3074 ---SEFFLDPESGELKTLALLDRERIPVYSLMAKATDGGG---------RFCQSNIHLIL 3121
Query: 367 LNMNDEPPVCNPPHLETQIY 386
++ND PPV + H T +Y
Sbjct: 3122 EDVNDNPPVFSSDHYNTCVY 3141
Score = 54.3 bits (129), Expect = 3e-07
Identities = 78/354 (22%), Positives = 143/354 (40%), Gaps = 54/354 (15%)
Query: 39 GSGVITATKIFNYETDPIRFLLIVD---TGRLYRHVLTINIIDVPESPNCTADPKFSSGT 95
GS V+ T + + + + ++ TG +++ + II + + P+ T +F
Sbjct: 1582 GSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSI 1641
Query: 96 ATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIA 155
+ +I R++ T + N + D+ A V E +G +
Sbjct: 1642 KVTDQGSPPMSATAIVRISVT--MSDNSHPKFIHKDYQAE--------VNENVDIGTSVI 1691
Query: 156 RVKATDRDEDSSIIYSFKTQQ--KMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATD 213
+ A + S++IY K +F ++P++G IT + L+ + S+ Y L +AT+
Sbjct: 1692 LISAISQ---STLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSS---YQLIIQATN 1745
Query: 214 NGNNTSSYTFTVFV--ENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFS 271
S+ T + + EN + P+ +S ++E PI S
Sbjct: 1746 MAGMASNATVNIQIVDENDNAPVFLFSQYS------------GSLSEAAPINSI----VR 1789
Query: 272 VFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGNLGTPPKFY-IEPDTGVIKLLDSLNR 329
+NSP+ + TDAD N + Y +V T KF+ ++ TG I+ + +L+
Sbjct: 1790 SLDNSPL-----VIRATDADSNRNALLVYQIVES---TAKKFFTVDSSTGAIRTIANLDH 1841
Query: 330 EIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLET 383
E + + V V D + P +V I V ++ND PPV ET
Sbjct: 1842 ETIAHFHFHVHVRDSGS-----PQLTAESPVEVNIEVTDVNDNPPVFTQAVFET 1890
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/223 (22%), Positives = 99/223 (44%), Gaps = 37/223 (16%)
Query: 126 LNVGGDHCARPFPLDSINVTEKKSVGEIIARVKATDRDE--DSSIIYSFK--TQQKMFCL 181
+N G + + FP D + V E VG I ++KA D D + ++++ F +
Sbjct: 718 INRQGPYFDKSFPSD-VAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNI 776
Query: 182 DPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFS 241
D TG + +L P++ ++ + +Y L D GN S ++ + NV+D
Sbjct: 777 DMETGQLKVLMPMDREH---TDLYLLNITIYDLGNPQKS-SWRLLTINVEDA-------- 824
Query: 242 TGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYT 300
N+ +P+ +++ ++ E+S + T + +V D D N + Y+
Sbjct: 825 ---------------NDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYS 869
Query: 301 VVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTD 343
V L +F I TG++ + D L+RE ++ Y + ++ D
Sbjct: 870 V----LTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARD 908
Score = 53.1 bits (126), Expect = 6e-07
Identities = 83/361 (22%), Positives = 138/361 (38%), Gaps = 80/361 (22%)
Query: 40 SGVITATKIFNYETDPIRFLLIV---DTGRLYRHVLTINIIDVPESPNCTADPKFSSGTA 96
+GVI+ T+ ++E+ P + IV D G YRH +N+
Sbjct: 525 TGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVT-----------------IR 567
Query: 97 TLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIAR 156
++++ PLF+ + A V + FP VG I
Sbjct: 568 IGNVNDNSPLFEKV----ACQGVISYD-------------FP-----------VGGHITA 599
Query: 157 VKATDRDEDSSIIYSFKTQQKM--FCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDN 214
V A D DE + Y + ++ F L+P +G + L + L N ++L ATD
Sbjct: 600 VSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGN-FALRITATDG 658
Query: 215 GNNTSSYTFTVFVEN---VDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF--- 268
N + + V + SC + ++++ +LN F
Sbjct: 659 ENLADPMSINISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSI 718
Query: 269 -------------TFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYI 314
+V E+ PV + K+ DAD FN + +T+ GN T F I
Sbjct: 719 NRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGN--TDSCFNI 776
Query: 315 EPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+ +TG +K+L ++RE Y + + + DL N Q+S +TI+V + ND P
Sbjct: 777 DMETGQLKVLMPMDREHTDLYLLNITIYDLGNP-------QKSSWRLLTINVEDANDNSP 829
Query: 375 V 375
V
Sbjct: 830 V 830
Score = 53.1 bits (126), Expect = 6e-07
Identities = 108/449 (24%), Positives = 176/449 (39%), Gaps = 73/449 (16%)
Query: 28 GAGLGPNQIMAGSGVITATKIFNYETDPIRFLLIVDTGR----LYRHV-LTINIIDVPES 82
G+GLG I SGVITA I + ET +L + T R LY + + I + DV ++
Sbjct: 1085 GSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDN 1144
Query: 83 PNCTADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSI 142
T++P + + E+ P S+ ++ A D ++ ++L P +I
Sbjct: 1145 APLTSEPIYYP-----VVMENSPKDVSVIQIQAEDPDSSSNEKLTY-RITSGNPQNFFAI 1198
Query: 143 NV-----------TEKKSVGEIIARVKATD---RDEDSSIIYSFKTQQKMFCLDPFTGTI 188
N+ +++ E V TD + S+I + + F +
Sbjct: 1199 NIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKV 1258
Query: 189 TLLQPLNLDNPSNSK-IYSLETEATDNGNNTS-SYTFT-------VFVENVDDPISCDPS 239
++ D + IY D G N SY+ F++ +S
Sbjct: 1259 YQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQ 1318
Query: 240 FSTGAAIITVIVRV-------SRINELN------PIGSASAFTF-------SVFENSPVD 279
F+ G+ I I V S L+ P S TF +V E+ V
Sbjct: 1319 FTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVT 1378
Query: 280 TLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAV 339
+VG V+ A+ P + + +VGGN + F E G I + L+ E S Y ++V
Sbjct: 1379 EIVGVVSVQPANTP---LWFDIVGGNFDS--AFDAEKGVGTIVIAKPLDAEQRSIYNMSV 1433
Query: 340 KVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYSTV-ESFHSAQLF 398
+VTD N A+ QV I VL+ ND P + P+ + I V Q+
Sbjct: 1434 EVTDGTNVAV----------TQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIE 1483
Query: 399 SKDSPQEH-LSYSIVGEQD--ESRKKRLE 424
+ D ++H LSY++ D RK R++
Sbjct: 1484 ATDRDEKHKLSYTVHSSIDSISMRKFRID 1512
Score = 52.4 bits (124), Expect = 1e-06
Identities = 75/282 (26%), Positives = 121/282 (42%), Gaps = 47/282 (16%)
Query: 141 SINVTEKKSVGEIIARVKATDRDED--SSIIYSFKTQQK-MFCLDPFTGTITLLQPLNLD 197
S+ V E VG +IA ++ D D + YS F +D +G I L + L+ +
Sbjct: 942 SVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYE 1001
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
+ Y+L A D G P+S +++ V V V +N
Sbjct: 1002 K---QQFYNLTVRAKDKGR----------------PVSL-------SSVSFVEVEVVDVN 1035
Query: 258 EL--NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGN-LGTPPKFY 313
E P A SV ENS + T V +VT D D + ++Y++ G+ LG +F
Sbjct: 1036 ENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLG---RFS 1092
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
I+ ++GVI D L+RE Y + V T D +P T +V I V ++ND
Sbjct: 1093 IDDESGVITAADILDRETMGSYWLTVYAT--DRGVVP-----LYSTIEVYIEVEDVNDNA 1145
Query: 374 PVCNPP-HLETQIYSTVESFHSAQLFSKD---SPQEHLSYSI 411
P+ + P + + ++ + Q+ ++D S E L+Y I
Sbjct: 1146 PLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRI 1187
Score = 52.4 bits (124), Expect = 1e-06
Identities = 70/289 (24%), Positives = 113/289 (39%), Gaps = 45/289 (15%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQ--KMFCLDPFTGTITLLQPLN 195
P + +V E + I + AT E IIY K F +D TG + ++ PL+
Sbjct: 2189 PFYTASVNEDIRMNTPILSINATS-PEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLD 2247
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGA-AIITVIVRVS 254
+ TS+Y T+ + TGA A +TV + V+
Sbjct: 2248 YEV-------------------TSAYKLTIRASDA----------LTGARAEVTVDLLVN 2278
Query: 255 RINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGNLGTPPKFY 313
+N+ PI + ++ E S + T V +V DAD N M Y +V + F+
Sbjct: 2279 DVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNSTDYFH 2338
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
I+ +G+I L+ E+ + V+ D ++ S V I + ++ND P
Sbjct: 2339 IDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSL-------SSEVLVHIYISDVNDNP 2391
Query: 374 PVCNPPHLETQIYSTVESFH---SAQLFSKDSPQ-EHLSYSIVGEQDES 418
PV N E+ + H Q DS + L YSI+ D +
Sbjct: 2392 PVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRT 2440
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/252 (21%), Positives = 97/252 (38%), Gaps = 39/252 (15%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLD 197
P + V E V EI+ V + F + GTI + +PL+ +
Sbjct: 1365 PFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAE 1424
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
S IY++ E TD T A+ V ++V N
Sbjct: 1425 QRS---IYNMSVEVTD---------------------------GTNVAVTQVFIKVLDNN 1454
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGG-NLGTPPKFYIEP 316
+ P S + ++ E+ DT + ++ TD D + + YTV + + KF I+P
Sbjct: 1455 DNGPEFSQPNYDVTISEDVLPDTEILQIEATDRD-EKHKLSYTVHSSIDSISMRKFRIDP 1513
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVC 376
TGV+ + L+ E + ++ + + V D + R A+V ++V + ND P
Sbjct: 1514 STGVLYTAERLDHEAQDKHILNIMVRDQE-------FPYRRNLARVIVNVEDANDHSPYF 1566
Query: 377 NPPHLETQIYST 388
P E ++ +
Sbjct: 1567 TNPLYEASVFES 1578
Score = 50.8 bits (120), Expect = 3e-06
Identities = 37/147 (25%), Positives = 72/147 (48%), Gaps = 18/147 (12%)
Query: 249 VIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGT 308
V ++V +N+L P+ S + ++ ++ E++P+ T V +VT TDAD N Y +
Sbjct: 144 VNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDL 203
Query: 309 PPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTD-----LDNDAIPDPLRQRSGTAQVT 363
F + P +GVI L LN + +++Y + + D N+ + S TA++
Sbjct: 204 ---FSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGV-------SSTAKLY 253
Query: 364 ISVLNMNDEPPVCNPPHLETQIYSTVE 390
+ + +N+ P H+ T + ++E
Sbjct: 254 VHIERINEHAPTI---HVVTHVPFSLE 277
Score = 50.4 bits (119), Expect = 4e-06
Identities = 71/321 (22%), Positives = 128/321 (39%), Gaps = 86/321 (26%)
Query: 32 GPNQIMAGSGVITATKIFNYETDPIRFLLIVDTGRLYRHVLT------INIIDVPESPNC 85
G +I +G I+ +++ +YE RF L+V+ L+ IN+ DV ++P
Sbjct: 3282 GKFKINPKTGGISVSEVLDYELCK-RFYLVVEAKDGGTPALSAVATVNINLTDVNDNP-- 3338
Query: 86 TADPKFSSGTATLEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSINVT 145
PKFS + I ED + S+ + A D
Sbjct: 3339 ---PKFSQDVYSAVISEDALVGDSVILLIAED---------------------------V 3368
Query: 146 EKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIY 205
+ + G+I + DRD + F +DP G + + + L+ + S Y
Sbjct: 3369 DSQPNGQIHFSIVNGDRDNE-------------FTVDPVLGLVKVKKKLDRERVSG---Y 3412
Query: 206 SLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSA 265
SL +A D+G S T TV N+D +S +N+ +P+ +
Sbjct: 3413 SLLVQAVDSGIPAMSSTATV---NID---------------------ISDVNDNSPVFTP 3448
Query: 266 SAFTFSVFENSPVDTLVGKVTFTDADWPFNN---MEYTVVGGNLGTPPKFYIEPDTGVIK 322
+ +T + EN PV T + ++ TD D F+N ++++ GN +F ++P G+++
Sbjct: 3449 ANYTAVIQENKPVGTSILQLVVTDRD-SFHNGPPFSFSILSGN--EEEEFVLDPH-GILR 3504
Query: 323 LLDSLNREIESQYKIAVKVTD 343
+Y + V+ D
Sbjct: 3505 SAVVFQHTESLEYVLCVQAKD 3525
Score = 47.0 bits (110), Expect = 4e-05
Identities = 64/282 (22%), Positives = 116/282 (41%), Gaps = 60/282 (21%)
Query: 101 DEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPF---PLDSINVTEKKSVGEIIARV 157
D+++P +++ RV E DH P+ PL +V E ++G + +V
Sbjct: 1540 DQEFPYRRNLARVIVNVED---------ANDHS--PYFTNPLYEASVFESAALGSAVLQV 1588
Query: 158 KATDRD--EDSSIIYSFKTQQ--KMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATD 213
A D+D E++ +IY+ + MF ++P G IT+ + ++ + L + TD
Sbjct: 1589 TALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQ---FVLSIKVTD 1645
Query: 214 NGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVF 273
G+ S T AI+ + V +S + +P + V
Sbjct: 1646 QGSPPMSAT----------------------AIVRISVTMS--DNSHPKFIHKDYQAEVN 1681
Query: 274 ENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIES 333
EN + T V ++ + + Y V G++ F I P +GVI +L+ E S
Sbjct: 1682 ENVDIGTSVILISAISQ----STLIYEVKDGDINGI--FTINPYSGVITTQKALDYERTS 1735
Query: 334 QYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
Y++ ++ T++ A A V I +++ ND PV
Sbjct: 1736 SYQLIIQATNMAGMA---------SNATVNIQIVDENDNAPV 1768
Score = 47.0 bits (110), Expect = 4e-05
Identities = 46/190 (24%), Positives = 82/190 (43%), Gaps = 17/190 (8%)
Query: 235 SCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWP- 293
S D F + ++ + V + +S +N+ P+ + + V E +P V V +DAD
Sbjct: 2366 SIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSD 2425
Query: 294 FNNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPL 353
F+ +EY+++ GN T F ++ +GVI L + + +E Y + V V+D
Sbjct: 2426 FDRLEYSILSGNDRT--SFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSD---------- 2473
Query: 354 RQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYSTVES----FHSAQLFSKDSPQEHLSY 409
+ TAQV I VL N P + ++ V + H +SY
Sbjct: 2474 GLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISY 2533
Query: 410 SIVGEQDESR 419
+I+ + + R
Sbjct: 2534 AIINDFAKDR 2543
Score = 43.1 bits (100), Expect = 6e-04
Identities = 56/244 (22%), Positives = 99/244 (40%), Gaps = 46/244 (18%)
Query: 144 VTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQK------MFCLDPFTGTITLLQPLN 195
+ E VG + +V+A D D + + YS + + F +D TG I+ L+ L+
Sbjct: 2823 IMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLD 2882
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSR 255
ET+ T +TF+V ++ + S ++ V VRV+
Sbjct: 2883 H-----------ETDPT--------FTFSVVASDLGEAFSL-------SSTALVSVRVTD 2916
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN--MEYTVVGGNLGTPPKFY 313
IN+ P+ + + +V E+ P +V ++ D D N + Y + GGN
Sbjct: 2917 INDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALG 2976
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
+ + + L+RE + Y + + TD A V +SV ++ND
Sbjct: 2977 LVQSEWKVYVKRPLDREEQDIYFLNITATD----------GLFVTQAMVEVSVSDVNDNS 3026
Query: 374 PVCN 377
PVC+
Sbjct: 3027 PVCD 3030
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSS--IIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
S+ + E + +A+V ATD D S+ Y FK + +F + P +G I+L LN D
Sbjct: 164 SVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDE 223
Query: 199 PSNSKIYSLETEATDN-----GNNTSSYTFTVFV 227
+ Y LE A D GNN S T ++V
Sbjct: 224 KNR---YDLEILAVDRGMKLYGNNGVSSTAKLYV 254
Score = 37.4 bits (85), Expect = 0.032
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 35/192 (18%)
Query: 157 VKATDRDEDSSIIYSFK----TQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEAT 212
++ATD D + + + ++ T +K F +D TG I + NLD+ +
Sbjct: 1798 IRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIA--NLDHET------------ 1843
Query: 213 DNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSV 272
+ + F V V + P T + + V + V+ +N+ P+ + + F +
Sbjct: 1844 -----IAHFHFHVHVRDSGSPQL------TAESPVEVNIEVTDVNDNPPVFTQAVFETIL 1892
Query: 273 FENSPVDTLVGKVTFTDADWPF-NNMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREI 331
+ V V KV+ TD D + Y+++ G+L F I+ ++GV+ + + N
Sbjct: 1893 LLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSL---DHFLIDSNSGVLTIKN--NNLS 1947
Query: 332 ESQYKIAVKVTD 343
+ Y + VKV+D
Sbjct: 1948 KDHYMLIVKVSD 1959
Score = 34.7 bits (78), Expect = 0.21
Identities = 64/290 (22%), Positives = 102/290 (35%), Gaps = 49/290 (16%)
Query: 144 VTEKKSVGEIIARVKATDRDEDS--SIIYSFKT--QQKMFCLDPFTGTITLLQPLNLDNP 199
V+E G + V+A+D D + YS + + F +D +G ITL N
Sbjct: 2403 VSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLS---NHRKQ 2459
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
+YSL +D +T T V +RV N
Sbjct: 2460 RMEPLYSLNVSVSDG-----LFTSTAQVH----------------------IRVLGANLY 2492
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPDT 318
+P S S + V EN T V V TD D + + Y ++ N +F I+
Sbjct: 2493 SPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAII--NDFAKDRFLID-SN 2549
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G + + L+RE + +++ V LD R+ V + V++ ND P
Sbjct: 2550 GQVITTERLDRENPLEGDVSIFVRALDGGG-------RTTFCTVRVIVVDENDNAPQFMT 2602
Query: 379 PHLETQIYSTVESFHSA----QLFSKDSPQEHLSYSIVGEQDESRKKRLE 424
+ + V H + D ++YS+ E S LE
Sbjct: 2603 VEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLE 2652
Score = 30.4 bits (67), Expect = 3.9
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 16/104 (15%)
Query: 312 FYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMND 371
F I P +G+I LN + YK+ +VT+ + D AQVTIS+ + ND
Sbjct: 420 FKINPRSGLIVTARPLNTVKKEVYKL--EVTNKEGDL----------KAQVTISIEDAND 467
Query: 372 EPPVCNPPHLETQIYSTV---ESFHSAQLFSKDSPQE-HLSYSI 411
P P + + +V S + KD + +++YSI
Sbjct: 468 HTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSI 511
Score = 30.4 bits (67), Expect = 3.9
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 245 AIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGG 304
A + V V + IN+ +P+ + +V ++ TL+ +VT D D N V+
Sbjct: 2066 ARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQD 2125
Query: 305 NLGTPPKFYIEPDTGVIKLLDSLNREIES-QYKIAVKVTD 343
+ G F I P++G + L ++ N ++ + +Y + + D
Sbjct: 2126 DYG---HFEINPNSGNVILKEAFNSDLSNIEYGVTILAKD 2162
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 72.8 bits (177), Expect = 7e-13
Identities = 64/215 (29%), Positives = 97/215 (45%), Gaps = 38/215 (17%)
Query: 165 DSSIIY--SFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYT 222
D SI Y S + +F +D TG I + L+ + + Y+L +A D N
Sbjct: 79 DGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQA---YYTLRAQALDRLTNK---- 131
Query: 223 FTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLV 282
P+ + F ++++ IN+ P +T V E SPV T V
Sbjct: 132 ----------PVEPESEF---------VIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSV 172
Query: 283 GKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIK-LLDSLNREIESQYKIAVKV 341
+VT TDAD P VV L P F +EP TGVIK L +++RE + QY + ++
Sbjct: 173 VQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQA 232
Query: 342 TDL--DNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
D+ N + SGT VT+++ ++ND PP
Sbjct: 233 KDMVGQNGGL-------SGTTSVTVTLTDVNDNPP 260
Score = 66.2 bits (160), Expect = 6e-11
Identities = 71/287 (24%), Positives = 120/287 (41%), Gaps = 36/287 (12%)
Query: 144 VTEKKSVGEIIARVKATDRDE-----DSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
V E VG + +V ATD D+ + ++YS Q F ++P TG I P N+D
Sbjct: 162 VPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALP-NMDR 220
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
+ + Y L +A D + T +V V ++ +N+
Sbjct: 221 EAKDQ-YLLVIQAKDMVGQNGGLSGTT----------------------SVTVTLTDVND 257
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPD 317
P ++ ++V E+ PV ++V ++ DAD N MEY +V G+ K ++ +
Sbjct: 258 NPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKE 317
Query: 318 T--GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
T G+I + L+ E ++ Y + ++ + D D L S T V I V ++ DEPPV
Sbjct: 318 TQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDV-DEPPV 376
Query: 376 CNPPHLETQIYSTVE---SFHSAQLFSKDSPQEHLSYSIVGEQDESR 419
+ P ++ + + DS + YSI D R
Sbjct: 377 FSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLER 423
Score = 57.8 bits (138), Expect = 2e-08
Identities = 59/235 (25%), Positives = 102/235 (43%), Gaps = 27/235 (11%)
Query: 143 NVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNS 202
NV E V ++AR+KA D D ++ +K G + +++D +
Sbjct: 270 NVPESLPVASVVARIKAADADIGANAEMEYKI---------VDGDGLGIFKISVDKETQE 320
Query: 203 KIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF-STG--AAIITVIVRVSRINEL 259
I +++ E +SYT + N D DP F S G + TV + V ++E
Sbjct: 321 GIITIQKELDFEAK--TSYTLRIEAANKD----ADPRFLSLGPFSDTTTVKIIVEDVDE- 373
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTG 319
P+ S+ + V E + V ++G V D D + + Y+ + N F I+ ++G
Sbjct: 374 PPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYS-IDRNTDLERYFNIDANSG 432
Query: 320 VIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
VI SL+RE + + I V + N + + G V I++L++ND P
Sbjct: 433 VITTAKSLDRETNAIHNITVLAMESQNPS-------QVGRGYVAITILDINDNAP 480
Score = 34.3 bits (77), Expect = 0.27
Identities = 53/238 (22%), Positives = 90/238 (37%), Gaps = 44/238 (18%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSII-YSFKTQ---QKMFCLDPFTGTITLLQP 193
PL + V+E VG II V A D D +S + YS ++ F +D +G IT +
Sbjct: 380 PLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKS 439
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
L+ ET A N TV +P + V + +
Sbjct: 440 LDR-----------ETNAIHN--------ITVLAMESQNPSQVGRGY--------VAITI 472
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEY-----TVVGGNLGT 308
IN+ P A + +V EN+ ++ K++ D D P N ++ T N
Sbjct: 473 LDINDNAP-EFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNF 531
Query: 309 PPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISV 366
K + ++ + R+ +S Y + + + D + ++ S T +TI V
Sbjct: 532 SLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSL-------SSTNTLTIRV 582
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 72.8 bits (177), Expect = 7e-13
Identities = 64/215 (29%), Positives = 97/215 (45%), Gaps = 38/215 (17%)
Query: 165 DSSIIY--SFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYT 222
D SI Y S + +F +D TG I + L+ + + Y+L +A D N
Sbjct: 79 DGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQA---YYTLRAQALDRLTNK---- 131
Query: 223 FTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLV 282
P+ + F ++++ IN+ P +T V E SPV T V
Sbjct: 132 ----------PVEPESEF---------VIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSV 172
Query: 283 GKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIK-LLDSLNREIESQYKIAVKV 341
+VT TDAD P VV L P F +EP TGVIK L +++RE + QY + ++
Sbjct: 173 VQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQA 232
Query: 342 TDL--DNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
D+ N + SGT VT+++ ++ND PP
Sbjct: 233 KDMVGQNGGL-------SGTTSVTVTLTDVNDNPP 260
Score = 66.2 bits (160), Expect = 6e-11
Identities = 71/287 (24%), Positives = 120/287 (41%), Gaps = 36/287 (12%)
Query: 144 VTEKKSVGEIIARVKATDRDE-----DSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
V E VG + +V ATD D+ + ++YS Q F ++P TG I P N+D
Sbjct: 162 VPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALP-NMDR 220
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
+ + Y L +A D + T +V V ++ +N+
Sbjct: 221 EAKDQ-YLLVIQAKDMVGQNGGLSGTT----------------------SVTVTLTDVND 257
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEPD 317
P ++ ++V E+ PV ++V ++ DAD N MEY +V G+ K ++ +
Sbjct: 258 NPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKE 317
Query: 318 T--GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
T G+I + L+ E ++ Y + ++ + D D L S T V I V ++ DEPPV
Sbjct: 318 TQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDV-DEPPV 376
Query: 376 CNPPHLETQIYSTVE---SFHSAQLFSKDSPQEHLSYSIVGEQDESR 419
+ P ++ + + DS + YSI D R
Sbjct: 377 FSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLER 423
Score = 57.8 bits (138), Expect = 2e-08
Identities = 59/235 (25%), Positives = 102/235 (43%), Gaps = 27/235 (11%)
Query: 143 NVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNS 202
NV E V ++AR+KA D D ++ +K G + +++D +
Sbjct: 270 NVPESLPVASVVARIKAADADIGANAEMEYKI---------VDGDGLGIFKISVDKETQE 320
Query: 203 KIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSF-STG--AAIITVIVRVSRINEL 259
I +++ E +SYT + N D DP F S G + TV + V ++E
Sbjct: 321 GIITIQKELDFEAK--TSYTLRIEAANKD----ADPRFLSLGPFSDTTTVKIIVEDVDE- 373
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTG 319
P+ S+ + V E + V ++G V D D + + Y+ + N F I+ ++G
Sbjct: 374 PPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYS-IDRNTDLERYFNIDANSG 432
Query: 320 VIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
VI SL+RE + + I V + N + + G V I++L++ND P
Sbjct: 433 VITTAKSLDRETNAIHNITVLAMESQNPS-------QVGRGYVAITILDINDNAP 480
Score = 34.3 bits (77), Expect = 0.27
Identities = 53/238 (22%), Positives = 90/238 (37%), Gaps = 44/238 (18%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSII-YSFKTQ---QKMFCLDPFTGTITLLQP 193
PL + V+E VG II V A D D +S + YS ++ F +D +G IT +
Sbjct: 380 PLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKS 439
Query: 194 LNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRV 253
L+ ET A N TV +P + V + +
Sbjct: 440 LDR-----------ETNAIHN--------ITVLAMESQNPSQVGRGY--------VAITI 472
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEY-----TVVGGNLGT 308
IN+ P A + +V EN+ ++ K++ D D P N ++ T N
Sbjct: 473 LDINDNAP-EFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNF 531
Query: 309 PPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISV 366
K + ++ + R+ +S Y + + + D + ++ S T +TI V
Sbjct: 532 SLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSL-------SSTNTLTIRV 582
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 72.0 bits (175), Expect = 1e-12
Identities = 68/253 (26%), Positives = 117/253 (46%), Gaps = 30/253 (11%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSSIIYSFK-TQQKMFCLDPFTGTITLLQPLNLDNPS 200
+ ++E S G I A D D S + +++ T ++F L+ T
Sbjct: 136 LEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT------------RGD 183
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
S+ L E + + S Y+F + + DP P T + + ++V+ N+ N
Sbjct: 184 GSRFAELVVEKSLDRETQSHYSFRITALDGGDP----PRLGT----VGLSIKVTDSNDNN 235
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVG-GNLGTPPKFYIEPDT 318
P+ S S + SV ENSP +T V ++ +D D N + Y+ G N T F I+P +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G++ + +L+ E Y++ V+ DL ++IP +VT+SVL+ ND PPV N
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIP-------AHCKVTVSVLDTNDNPPVINL 348
Query: 379 PHLETQIYSTVES 391
+ +++ ES
Sbjct: 349 LSVNSELVEVSES 361
Score = 43.9 bits (102), Expect = 3e-04
Identities = 60/248 (24%), Positives = 93/248 (37%), Gaps = 43/248 (17%)
Query: 142 INVTEKKSVGEIIARVKATDRDED-SSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPS 200
+ V+E G +IA V+ +DRD + + F L + T+L LD
Sbjct: 356 VEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQ 415
Query: 201 NSKIYSLETEATDNG----NNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
+ + Y+L +A D G + S+T + EN + P P + VIV+ +
Sbjct: 416 HDQ-YNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQ-------VIVQEN-- 465
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKF---Y 313
+ A+ SV P L G V+ Y +V + P F
Sbjct: 466 ------NTPGAYLLSVSARDPDLGLNGSVS------------YQIVPSQVRDMPVFTYVS 507
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
I P++G I L S N E ++ V D L A V + +L++ND
Sbjct: 508 INPNSGDIYALRSFNHEQTKAFEFKVLAKD-------GGLPSLQSNATVRVIILDVNDNT 560
Query: 374 PVCNPPHL 381
PV P L
Sbjct: 561 PVITAPPL 568
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 72.0 bits (175), Expect = 1e-12
Identities = 68/253 (26%), Positives = 117/253 (46%), Gaps = 30/253 (11%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSSIIYSFK-TQQKMFCLDPFTGTITLLQPLNLDNPS 200
+ ++E S G I A D D S + +++ T ++F L+ T
Sbjct: 136 LEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT------------RGD 183
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
S+ L E + + S Y+F + + DP P T + + ++V+ N+ N
Sbjct: 184 GSRFAELVVEKSLDRETQSHYSFRITALDGGDP----PRLGT----VGLSIKVTDSNDNN 235
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVG-GNLGTPPKFYIEPDT 318
P+ S S + SV ENSP +T V ++ +D D N + Y+ G N T F I+P +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G++ + +L+ E Y++ V+ DL ++IP +VT+SVL+ ND PPV N
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIP-------AHCKVTVSVLDTNDNPPVINL 348
Query: 379 PHLETQIYSTVES 391
+ +++ ES
Sbjct: 349 LSVNSELVEVSES 361
Score = 43.9 bits (102), Expect = 3e-04
Identities = 60/248 (24%), Positives = 93/248 (37%), Gaps = 43/248 (17%)
Query: 142 INVTEKKSVGEIIARVKATDRDED-SSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPS 200
+ V+E G +IA V+ +DRD + + F L + T+L LD
Sbjct: 356 VEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQ 415
Query: 201 NSKIYSLETEATDNG----NNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRI 256
+ + Y+L +A D G + S+T + EN + P P + VIV+ +
Sbjct: 416 HDQ-YNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQ-------VIVQEN-- 465
Query: 257 NELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKF---Y 313
+ A+ SV P L G V+ Y +V + P F
Sbjct: 466 ------NTPGAYLLSVSARDPDLGLNGSVS------------YQIVPSQVRDMPVFTYVS 507
Query: 314 IEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
I P++G I L S N E ++ V D L A V + +L++ND
Sbjct: 508 INPNSGDIYALRSFNHEQTKAFEFKVLAKD-------GGLPSLQSNATVRVIILDVNDNT 560
Query: 374 PVCNPPHL 381
PV P L
Sbjct: 561 PVITAPPL 568
>gi|40255133 hypothetical protein LOC222256 [Homo sapiens]
Length = 885
Score = 72.0 bits (175), Expect = 1e-12
Identities = 66/249 (26%), Positives = 111/249 (44%), Gaps = 42/249 (16%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSII---YSFKTQQKM-----FCLDPF-TGTITLL 191
SI V E+ + G ++ + D+DS ++F + F DP +G I L+
Sbjct: 351 SIMVPERTAKGTLLLDLNKFCFDDDSEAPNNRFNFTMPSGVGSGSRFLQDPAGSGKIVLI 410
Query: 192 QPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIV 251
L+ +NPSN GN YT + V++V P + + V +
Sbjct: 411 GDLDYENPSNLAA----------GNK---YTVIIQVQDVAPPYYKNNVY--------VYI 449
Query: 252 RVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVV--GGNLGTP 309
S NE I ++ F V E P T VG+V TD D P +++ Y++ G +L P
Sbjct: 450 LTSPENEFPLIFDRPSYVFDVSERRPARTRVGQVRATDKDLPQSSLLYSISTGGASLQYP 509
Query: 310 PKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNM 369
F+I P TG ++L+ ++ E Y + ++ T+ + + + VT+++L
Sbjct: 510 NVFWINPKTGELQLVTKVDCETTPIYILRIQATN----------NEDTSSVTVTVNILEE 559
Query: 370 NDEPPVCNP 378
NDE P+C P
Sbjct: 560 NDEKPICTP 568
Score = 53.5 bits (127), Expect = 4e-07
Identities = 66/248 (26%), Positives = 106/248 (42%), Gaps = 59/248 (23%)
Query: 143 NVTEKKSVGEIIARVKATDRD-EDSSIIYSFKT------QQKMFCLDPFTGTITLLQPLN 195
+V+E++ + +V+ATD+D SS++YS T +F ++P TG + L+ ++
Sbjct: 469 DVSERRPARTRVGQVRATDKDLPQSSLLYSISTGGASLQYPNVFWINPKTGELQLVTKVD 528
Query: 196 LDNPSNSKIYSLETEATDNGNNTSSYTFTVFV--ENVDDPISCDPSFSTGAAIITVIVRV 253
+ + IY L +AT+N +TSS T TV + EN + PI C P+
Sbjct: 529 CET---TPIYILRIQATNN-EDTSSVTVTVNILEENDEKPI-CTPN-------------- 569
Query: 254 SRINELNPIGSASAFTFSVFENSPVDTLVG------KVTFTDADWPFNNMEYTVVGGNLG 307
S F PVD VG K+T TD D + Y++ GN+
Sbjct: 570 -----------------SYFLALPVDLKVGTNIQNFKLTCTDLDSSPRSFRYSIGPGNVN 612
Query: 308 TPPKFYIEPDTGVIKLLDSLNREIES------QYKIAVKVTD--LDNDAIPDPLRQRSGT 359
F + V +LL + + YK+ V VTD L +D +GT
Sbjct: 613 NHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYKLLVYVTDDNLMSDRKKAEALVETGT 672
Query: 360 AQVTISVL 367
++I V+
Sbjct: 673 VTLSIKVI 680
Score = 50.8 bits (120), Expect = 3e-06
Identities = 78/300 (26%), Positives = 124/300 (41%), Gaps = 60/300 (20%)
Query: 72 LTINIIDVPESPNCTADPKFSSGTATLEIDEDYPLFQSIYRVT------ATDEVFANGDR 125
L+ +I P+S +A+ S T L+ + + F I V A+ E+ N
Sbjct: 170 LSYFLISPPKSFRMSANGTLFS-TTELDFEAGHRSFHLIVEVRDSGGLKASTELQVNIVN 228
Query: 126 LNVGGDHCAR-PFPLDSINVTEKKSVGEIIARVKATDRDED---SSIIYSFKTQQKMFCL 181
LN D R P V E+ S G I+A + A D D++ S ++YS T K F +
Sbjct: 229 LN---DEVPRFTSPTRVYTVLEELSPGTIVANITAEDPDDEGFPSHLLYSITTVSKYFMI 285
Query: 182 DPFTGTITLLQPLNLD--NPSNSKIYSLETEATDN--GNNTSSYTFTVFVENVDDPISCD 237
+ TGTI + Q ++ D + SLE D G + T VE+V+D
Sbjct: 286 NQLTGTIQVAQRIDRDAGELRQNPTISLEVLVKDRPYGGQENRIQITFIVEDVND----- 340
Query: 238 PSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVF--ENSPVDTL---VGKVTF-TDAD 291
NP + FTFS+ E + TL + K F D++
Sbjct: 341 ----------------------NP-ATCQKFTFSIMVPERTAKGTLLLDLNKFCFDDDSE 377
Query: 292 WPFNNMEYTVVGGNLGTPPKFYIEP-DTGVIKLLDSLNREIES------QYKIAVKVTDL 344
P N +T+ G +G+ +F +P +G I L+ L+ E S +Y + ++V D+
Sbjct: 378 APNNRFNFTMPSG-VGSGSRFLQDPAGSGKIVLIGDLDYENPSNLAAGNKYTVIIQVQDV 436
Score = 37.4 bits (85), Expect = 0.032
Identities = 56/243 (23%), Positives = 102/243 (41%), Gaps = 51/243 (20%)
Query: 144 VTEKKSVGEIIARVKATDRDEDSSII---YSFKTQQKMFCLDPFTGTITLLQPLNLDNPS 200
+ E+ + G I +V+A D ++ S I Y + K F + + TL LD +
Sbjct: 144 IVERANPG-FIYQVEAFDPEDTSRNIPLSYFLISPPKSFRM---SANGTLFSTTELDFEA 199
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
+ + L E D+G +S V + N++D + P F++ + TV+ EL+
Sbjct: 200 GHRSFHLIVEVRDSGGLKASTELQVNIVNLNDEV---PRFTSPTRVYTVL------EELS 250
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDAD---WPFNNMEYTVVGGNLGTPPKFY-IEP 316
P T+V +T D D +P +++ Y++ T K++ I
Sbjct: 251 P-----------------GTIVANITAEDPDDEGFP-SHLLYSIT-----TVSKYFMINQ 287
Query: 317 DTGVIKLLDSLNR---EIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEP 373
TG I++ ++R E+ I+++V D P + Q+T V ++ND P
Sbjct: 288 LTGTIQVAQRIDRDAGELRQNPTISLEVLVKDR-----PYGGQENRIQITFIVEDVNDNP 342
Query: 374 PVC 376
C
Sbjct: 343 ATC 345
>gi|47059046 dachsous 2 isoform 1 [Homo sapiens]
Length = 2916
Score = 71.6 bits (174), Expect = 2e-12
Identities = 65/246 (26%), Positives = 110/246 (44%), Gaps = 49/246 (19%)
Query: 142 INVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQP-LNLDNPS 200
+ V E VG + + ATD + + +I Y + K F +DP GTI + P L LD S
Sbjct: 1999 VTVPESIPVGYSVLTLSATDLESNENISYRILSSSKEFSIDPKNGTIFTISPVLLLDTIS 2058
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
++ EA+D GN P A+ V + + +N
Sbjct: 2059 TTQFL---VEASDGGN---------------------PDL---RALTLVEIGIEDMNNYA 2091
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN--MEYTVVGGNLGTPPKFYIE--- 315
P + ++ S+ E++ V + + + D DW N +EY+++ GN + F++E
Sbjct: 2092 PEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGN--SQNNFHVETKF 2149
Query: 316 -------PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLN 368
G + LL SL+RE + +++ + L +D+ PL S TA ++I VL+
Sbjct: 2150 FHSEYPYKQVGYLVLLHSLDREASASHELVI----LASDSGCPPL---SSTAVISIQVLD 2202
Query: 369 MNDEPP 374
+ND PP
Sbjct: 2203 VNDNPP 2208
Score = 55.5 bits (132), Expect = 1e-07
Identities = 69/281 (24%), Positives = 119/281 (42%), Gaps = 46/281 (16%)
Query: 143 NVTEKKSVGEIIARVKATDRDE--DSSIIYSFKT--QQKMFCLDPFTGTITLLQPLNLDN 198
+V+E + + +V ATD D + I YS + Q++ F +D +G IT L+ +
Sbjct: 1795 SVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVITTKAILDYEL 1854
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
S+ YSL +ATD G S T TV V D P+F A+
Sbjct: 1855 TSS---YSLIVQATDKGMPRLSNT-TVIKVQVTDINDNAPAFLPSEAV------------ 1898
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDT 318
+ E+S +V V+ D D + N GT KF I+ +T
Sbjct: 1899 ------------EITEDSLPGVIVTHVSVHDVDLNSAFIFSFAKESNPGT--KFAIDQNT 1944
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
GV+ L+ +L+ E ++Y++ ++++D + G + + VL++ND PPV +
Sbjct: 1945 GVVVLVKTLDFEEMTEYELLIQISD--------SVHYTEGA--LVVRVLDVNDNPPVFSQ 1994
Query: 379 PHLETQIYSTVESFHSAQLFSKD--SPQEHLSYSIVGEQDE 417
+ + ++ +S S E++SY I+ E
Sbjct: 1995 DFYQVTVPESIPVGYSVLTLSATDLESNENISYRILSSSKE 2035
Score = 52.0 bits (123), Expect = 1e-06
Identities = 66/239 (27%), Positives = 101/239 (42%), Gaps = 40/239 (16%)
Query: 144 VTEKKSVGEIIARVKATDRDE---DSSIIYSFKTQQK--MFCLDPFTGTITLLQPLNLDN 198
+ E +I++ +K++D + + + +S K F +D TG + L + L+ +
Sbjct: 957 IPENLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYET 1016
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVE-NVDDPISCDPSFSTGAAIITVIVRVSRIN 257
S+ Y TD+ N S + TVF+ +V+D PSF +I
Sbjct: 1017 TSH---YLFRVITTDHSKNLS-LSSTVFLSIDVEDQNDHSPSFQDELIVI---------- 1062
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNN--MEYTVVGGNLGTPPKFYIE 315
SV EN P+ TLV D D F N ++Y + N GT P F I
Sbjct: 1063 -------------SVEENVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPGTNP-FLIH 1108
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
P G + + L+R ES + + VT D R RS TAQ+ I L++ND P
Sbjct: 1109 PSFGTLVTVSRLDR--ESIPTVILTVTASDQAVNVTDRRLRSLTAQIVI--LDVNDHNP 1163
Score = 48.9 bits (115), Expect = 1e-05
Identities = 88/411 (21%), Positives = 159/411 (38%), Gaps = 76/411 (18%)
Query: 44 TATKIFNYETDPIRFLLIVDTGRLYRHVLTINIIDVPESPNCTADPKFSSGTATLEIDED 103
T +FN + D FL R+ ++ + N P + P F + +D +
Sbjct: 1072 TLVYVFNAKDDDGSFL----NSRIQYYIESHN----PGTNPFLIHPSFGTLVTVSRLDRE 1123
Query: 104 YPLFQSIYRVTATDEVFANGDR-----------LNVGGDHCARPFPLDSINVTEKKSVGE 152
+ I VTA+D+ DR L+V DH + +V E +VG
Sbjct: 1124 -SIPTVILTVTASDQAVNVTDRRLRSLTAQIVILDVN-DHNPTFISFPNAHVKEDVTVGS 1181
Query: 153 IIARVKATDRDE--DSSIIYSFKT--QQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLE 208
++ + A D DE + + YS + + F LD +G +T PL+ Y ++
Sbjct: 1182 LVHHITAHDPDEGRNGKVTYSILSGNENMTFMLDESSGLLTTTCPLD---------YEMK 1232
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
T+ + TV +DD P+ S+ T+ V V +N+ P+ +
Sbjct: 1233 TQ----------HILTVLA--LDDG---TPALSSSQ---TLTVTVLDVNDEAPVFKQHLY 1274
Query: 269 TFSVFENSPVDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIEPDTGVIKLLDSL 327
SV EN V +V D D N+ +++ ++ G + F I DTG + L
Sbjct: 1275 EASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPG--ASFELFEINSDTGEVVTTTIL 1332
Query: 328 NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYS 387
+REI+ + + V V D ++ S T + +V + ND P
Sbjct: 1333 DREIQEVFTLRVLVRDGGFPSL-------SSTTTILCTVEDENDHAP------------E 1373
Query: 388 TVESFHSAQLFSKDSPQEHLSYSIVGEQDESRKKRLEKMSLSSYYFKKCFT 438
+ S + ++ P+ + Y+++ ++ R + + +CFT
Sbjct: 1374 FIVSSYDIEVLENQEPE--VVYTVLASDMDAGNNRAVEYHIIDGNTDECFT 1422
Score = 48.5 bits (114), Expect = 1e-05
Identities = 69/278 (24%), Positives = 108/278 (38%), Gaps = 42/278 (15%)
Query: 98 LEIDEDYPLFQSIYRVTATDEVFANGDRLNVGGDHCARPFPLDSINVTEKKSVGEIIARV 157
L +D+ P S +T T V D V H L +V E ++ GE + RV
Sbjct: 1240 LALDDGTPALSSSQTLTVT--VLDVNDEAPVFKQH------LYEASVKENQNPGEFVTRV 1291
Query: 158 KATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNN 217
+A DRD + F+ G L +N D L+ E +
Sbjct: 1292 EALDRDSGVNSKLQFEI---------MPGASFELFEINSDTGEVVTTTILDREIQE---- 1338
Query: 218 TSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSP 277
+T V V D F + ++ T++ V N+ P S++ V EN
Sbjct: 1339 --VFTLRVLVR--------DGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLENQE 1388
Query: 278 VDTLVGKVTFTDADWPFNN-MEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYK 336
+ +V V +D D N +EY ++ GN T F I +G + +L+RE S +
Sbjct: 1389 PE-VVYTVLASDMDAGNNRAVEYHIIDGN--TDECFTINEMSGELSTTRALDREQISNFT 1445
Query: 337 IAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+ + +DL DP RS + + VL+ ND P
Sbjct: 1446 LVILCSDLG-----DP--PRSSVIHLQVRVLDANDHSP 1476
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 25/185 (13%)
Query: 236 CDPSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN 295
C P ST + ++V +N+ P S+ ++ V E++P+ + + V+ D D +
Sbjct: 2187 CPPLSSTAV----ISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRDTGSH 2242
Query: 296 -NMEYTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLR 354
+ Y ++ GN FY+E +TGV+ L+ L+ E +++ + V+ +D + +
Sbjct: 2243 AEIIYNIISGN--EKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAE--------K 2292
Query: 355 QRSGTAQVTISVLNMNDEPP-------VCNPPHLETQIYSTVESFHSAQLFSKDSPQEHL 407
+ A V +SVL+ ND P C P I ST+ S ++ + P L
Sbjct: 2293 KHFSFAVVFVSVLDDNDHAPQFMFSSFSCIVPE-NLPISSTICSINALDFDA--GPYGEL 2349
Query: 408 SYSIV 412
+YSIV
Sbjct: 2350 TYSIV 2354
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/194 (22%), Positives = 81/194 (41%), Gaps = 38/194 (19%)
Query: 131 DHCARPFPLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQK---MFCLDPFTGT 187
D+ P +++ +TE G I+ V D D +S+ I+SF + F +D TG
Sbjct: 1887 DNAPAFLPSEAVEITEDSLPGVIVTHVSVHDVDLNSAFIFSFAKESNPGTKFAIDQNTGV 1946
Query: 188 ITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAII 247
+ L++ L+ + + Y L + +D+ + T
Sbjct: 1947 VVLVKTLDFEEMTE---YELLIQISDSVHYTEG--------------------------- 1976
Query: 248 TVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLG 307
++VRV +N+ P+ S + +V E+ PV V ++ TD + N+ Y + L
Sbjct: 1977 ALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYSVLTLSATDLE-SNENISYRI----LS 2031
Query: 308 TPPKFYIEPDTGVI 321
+ +F I+P G I
Sbjct: 2032 SSKEFSIDPKNGTI 2045
Score = 47.4 bits (111), Expect = 3e-05
Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 19/168 (11%)
Query: 209 TEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPIGSASAF 268
T A D S++T + ++ DP +++I + VRV N+ +P +
Sbjct: 1433 TRALDR-EQISNFTLVILCSDLGDP--------PRSSVIHLQVRVLDANDHSPSFPTLYY 1483
Query: 269 TFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGNLGTPPKFYIEPDTGVIKLLDSL 327
SV E++ V T+V ++ D D N EY + G F I+P +G +K ++L
Sbjct: 1484 QSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGA---FTIDPMSGTLKTSNTL 1540
Query: 328 NREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
+RE SQ+ + D RS T + + V ++ND PV
Sbjct: 1541 DREARSQHTFSAVARDCSIQG------SRSTTVIIKVYVTDVNDNDPV 1582
Score = 45.4 bits (106), Expect = 1e-04
Identities = 38/135 (28%), Positives = 61/135 (45%), Gaps = 10/135 (7%)
Query: 245 AIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVG 303
A V V + N+ +P S + SV E+ + V +V TD D N + EY+++
Sbjct: 1769 AYCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILS 1828
Query: 304 GNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVT 363
GN F I+ +GVI L+ E+ S Y + V+ TD + + S T +
Sbjct: 1829 GN--QEEAFQIDALSGVITTKAILDYELTSSYSLIVQATD-------KGMPRLSNTTVIK 1879
Query: 364 ISVLNMNDEPPVCNP 378
+ V ++ND P P
Sbjct: 1880 VQVTDINDNAPAFLP 1894
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 34/151 (22%)
Query: 178 MFCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCD 237
+F +DP TG I Q L+ +N + Y L +A D G+ T+S V +E +D
Sbjct: 2369 LFLIDPLTGDIHAKQILDYENGNK---YCLTVQAKDKGDATASLVVWVDIEGID------ 2419
Query: 238 PSFSTGAAIITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM 297
E PI + + F++ E + L+G+V +DAD +
Sbjct: 2420 --------------------EFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDG- 2458
Query: 298 EYTVVGGNLGT-PPKFYIEPDTGVIKLLDSL 327
V+ +LGT P F + G I L+ +L
Sbjct: 2459 ---VILYSLGTSSPFFSVNKTNGNIYLIRAL 2486
Score = 40.0 bits (92), Expect = 0.005
Identities = 43/155 (27%), Positives = 68/155 (43%), Gaps = 20/155 (12%)
Query: 268 FTFSVFENSPVDTLVGKVTFTDADWPFNNME---YTVVGGNLGTPPKFYIEPDTGVIKLL 324
+TF V+E+ P D+ +G V A P N+ E Y + G+LG KF I P G I+
Sbjct: 382 YTFLVYEDVPEDSPIGTV---KAREPLNSSEPIFYRISSGDLG--GKFSIHPRLGTIRTR 436
Query: 325 DSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQ 384
L+ E + + V + P + +V I+V+++ND P E +
Sbjct: 437 KPLDHETQ---PVVVLTVQAQLGSAP-----ACSSTEVNITVMDVNDNHPAFLRTSDEIR 488
Query: 385 IYSTV---ESFHSAQLFSKDSPQEHL-SYSIVGEQ 415
I T + + A+ +DS + L YSI Q
Sbjct: 489 ISQTTPPGTALYLARAEDRDSGRNGLIRYSIASPQ 523
Score = 39.7 bits (91), Expect = 0.006
Identities = 68/283 (24%), Positives = 111/283 (39%), Gaps = 49/283 (17%)
Query: 143 NVTEKKSVGEIIARVKATDRDED-SSIIYSFKTQQKM--FCLDPFTGTITLLQPLNLDNP 199
+V E VG ++ + A D+DE + F T + F +DP +GT
Sbjct: 1486 SVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGAFTIDPMSGT------------ 1533
Query: 200 SNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINEL 259
L+T T + S +TF+ + C S +I + V V+ +N+
Sbjct: 1534 -------LKTSNTLDREARSQHTFSAVARD------CSIQGSRSTTVI-IKVYVTDVNDN 1579
Query: 260 NPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTG 319
+P+ + F + SP + V D D N TVV T F I+ TG
Sbjct: 1580 DPVLEQNPFDVFLSPESPTNQTTVIVRADDLDLGPNG---TVVFSFAETQSMFSIDKYTG 1636
Query: 320 VIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPP 379
I+ + + E + + +KVTD P R +G + V++M E +
Sbjct: 1637 EIQFQQNPSSEYFPIW-LQLKVTDQG-----IPARTTTG-----LLVIHMEGEDVKISFS 1685
Query: 380 H-----LETQIYSTVESFHSAQLFSKDSPQEHLSYSIV-GEQD 416
H L T+ S + + F+ DS Q+ + YSI G +D
Sbjct: 1686 HHLYKGLVTENCEAGTSIVTVKAFAPDSIQDSMKYSIFSGNED 1728
Score = 36.6 bits (83), Expect = 0.055
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 284 KVTFTDADWP-FNNMEYTVVGGNLG--TPPKFYIEPDTGVIKLLDSLNREIE-SQYKIAV 339
+VT +DAD + +EY++ G L P F I+P G I + ++RE + + Y + V
Sbjct: 78 EVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLV 137
Query: 340 KVTDLDNDAIPDPLRQRSGT---AQVTISVLNMNDEPPVCNPPHLETQI 385
+ D D + + G A V + + ++ND PV NP T I
Sbjct: 138 EAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSI 186
Score = 32.3 bits (72), Expect = 1.0
Identities = 35/157 (22%), Positives = 65/157 (41%), Gaps = 27/157 (17%)
Query: 179 FCLDPFTGTITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDP 238
F +DP G I + Q ++D + Y L EA D ++ V
Sbjct: 109 FRIDPHDGQICVSQ--DIDRERDPATYDLLVEAKDGDEQRMTHLALV------------- 153
Query: 239 SFSTGAAIITVIVRVSR--INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFN 295
G VRV +N+ +P+ + S + S+ + + T + V TD D +
Sbjct: 154 ---KGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYG 210
Query: 296 NMEYTVVGGNLGTPPKFYIEPDTGV----IKLLDSLN 328
+ Y ++ GN+ + F I+ TG+ +++L ++N
Sbjct: 211 TVAYELIPGNVSS--LFTIDSTTGLYSPEVEILSAVN 245
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 71.6 bits (174), Expect = 2e-12
Identities = 72/239 (30%), Positives = 100/239 (41%), Gaps = 42/239 (17%)
Query: 146 EKKSVGEIIARVKATDRDEDSS--IIYSFKTQ---QKMFCLDPFTGTITLLQPLNLDNPS 200
E GE+IA + A+D D S+ ++YS + + + +F + P TG I + L+ +
Sbjct: 517 ENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRE 576
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
+ Y L+ A D G+ + T TV V NV D DP F
Sbjct: 577 S---YELKVVAADRGSPSLQGTATVLV-NVLDCNDNDPKFML------------------ 614
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGV 320
S + FSV EN P + VG VT D D N V + G F I+ TG
Sbjct: 615 -----SGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG---DFVIQNGTGT 666
Query: 321 IKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPP 379
I S +RE +S Y +K D +P RS VTI+VL+ ND P P
Sbjct: 667 ILSSLSFDREQQSTYTFQLKAVD---GGVP----PRSAYVGVTINVLDENDNAPYITAP 718
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 24/232 (10%)
Query: 143 NVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNS 202
N++E + +A V+ +DRDE + + C+ L Q + S
Sbjct: 403 NISEDVAEETAVALVQVSDRDEGENAAVT--------CVVAGDVPFQLRQASETGSDSKK 454
Query: 203 KIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPI 262
K Y L+T + YT + + +P P ST + + V+ +N+ P+
Sbjct: 455 K-YFLQTTTPLDYEKVKDYTIEIVAVDSGNP----PLSSTNSLKVQVV----DVNDNAPV 505
Query: 263 GSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIK 322
+ S + EN+ ++ ++T +DAD N + F I P+TG I+
Sbjct: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQ 565
Query: 323 LLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+ SL+RE Y++ V D + ++ GTA V ++VL+ ND P
Sbjct: 566 VKTSLDREQRESYELKVVAADRGSPSL-------QGTATVLVNVLDCNDNDP 610
Score = 45.8 bits (107), Expect = 9e-05
Identities = 54/238 (22%), Positives = 101/238 (42%), Gaps = 24/238 (10%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLD 197
P+ ++ + E ++G + A+DRD + + S++ Q + F + + +
Sbjct: 171 PVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFG--LQVAEDQEEK 228
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
P + +L+ E D SY T+ V++ P P S+ +TV+ N
Sbjct: 229 QPQLIVMGNLDRERWD------SYDLTIKVQDGGSP----PRASSALLRVTVL----DTN 274
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEP 316
+ P ++ + ENSP+ V +V D+D N +EYT ++
Sbjct: 275 DNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDR 334
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+TG+I + ++RE S + +V D + +S AQV ++V +MND P
Sbjct: 335 NTGLITVQGPVDREDLSTLRFSVLAKDRGTNP-------KSARAQVVVTVKDMNDNAP 385
Score = 33.5 bits (75), Expect = 0.46
Identities = 37/161 (22%), Positives = 67/161 (41%), Gaps = 14/161 (8%)
Query: 251 VRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGN---- 305
+ V IN+ P ++ T ++ EN+ + +L +D D N + Y + G
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 306 -LGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
G E + ++ +L+RE Y + +KV D + R+ +A + +
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPP-------RASSALLRV 268
Query: 365 SVLNMNDEPPVCNPPHLETQIYSTVESFHSA-QLFSKDSPQ 404
+VL+ ND P P E ++ HS Q+ + DS Q
Sbjct: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ 309
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 71.6 bits (174), Expect = 2e-12
Identities = 72/239 (30%), Positives = 100/239 (41%), Gaps = 42/239 (17%)
Query: 146 EKKSVGEIIARVKATDRDEDSS--IIYSFKTQ---QKMFCLDPFTGTITLLQPLNLDNPS 200
E GE+IA + A+D D S+ ++YS + + + +F + P TG I + L+ +
Sbjct: 517 ENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRE 576
Query: 201 NSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELN 260
+ Y L+ A D G+ + T TV V NV D DP F
Sbjct: 577 S---YELKVVAADRGSPSLQGTATVLV-NVLDCNDNDPKFML------------------ 614
Query: 261 PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGV 320
S + FSV EN P + VG VT D D N V + G F I+ TG
Sbjct: 615 -----SGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG---DFVIQNGTGT 666
Query: 321 IKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPP 379
I S +RE +S Y +K D +P RS VTI+VL+ ND P P
Sbjct: 667 ILSSLSFDREQQSTYTFQLKAVD---GGVP----PRSAYVGVTINVLDENDNAPYITAP 718
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 24/232 (10%)
Query: 143 NVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNS 202
N++E + +A V+ +DRDE + + C+ L Q + S
Sbjct: 403 NISEDVAEETAVALVQVSDRDEGENAAVT--------CVVAGDVPFQLRQASETGSDSKK 454
Query: 203 KIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPI 262
K Y L+T + YT + + +P P ST + + V+ +N+ P+
Sbjct: 455 K-YFLQTTTPLDYEKVKDYTIEIVAVDSGNP----PLSSTNSLKVQVV----DVNDNAPV 505
Query: 263 GSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDTGVIK 322
+ S + EN+ ++ ++T +DAD N + F I P+TG I+
Sbjct: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQ 565
Query: 323 LLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+ SL+RE Y++ V D + ++ GTA V ++VL+ ND P
Sbjct: 566 VKTSLDREQRESYELKVVAADRGSPSL-------QGTATVLVNVLDCNDNDP 610
Score = 45.8 bits (107), Expect = 9e-05
Identities = 54/238 (22%), Positives = 101/238 (42%), Gaps = 24/238 (10%)
Query: 138 PLDSINVTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLD 197
P+ ++ + E ++G + A+DRD + + S++ Q + F + + +
Sbjct: 171 PVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFG--LQVAEDQEEK 228
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
P + +L+ E D SY T+ V++ P P S+ +TV+ N
Sbjct: 229 QPQLIVMGNLDRERWD------SYDLTIKVQDGGSP----PRASSALLRVTVL----DTN 274
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTPPKFYIEP 316
+ P ++ + ENSP+ V +V D+D N +EYT ++
Sbjct: 275 DNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDR 334
Query: 317 DTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+TG+I + ++RE S + +V D + +S AQV ++V +MND P
Sbjct: 335 NTGLITVQGPVDREDLSTLRFSVLAKDRGTNP-------KSARAQVVVTVKDMNDNAP 385
Score = 33.5 bits (75), Expect = 0.46
Identities = 37/161 (22%), Positives = 67/161 (41%), Gaps = 14/161 (8%)
Query: 251 VRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNM-EYTVVGGN---- 305
+ V IN+ P ++ T ++ EN+ + +L +D D N + Y + G
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 306 -LGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
G E + ++ +L+RE Y + +KV D + R+ +A + +
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPP-------RASSALLRV 268
Query: 365 SVLNMNDEPPVCNPPHLETQIYSTVESFHSA-QLFSKDSPQ 404
+VL+ ND P P E ++ HS Q+ + DS Q
Sbjct: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ 309
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 70.5 bits (171), Expect = 3e-12
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Query: 250 IVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTP 309
++++ IN+ P +T SV E S V T V +VT TDAD P V+ L
Sbjct: 147 VIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQ 206
Query: 310 PKFYIEPDTGVIK-LLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLN 368
P F +EP+TG+I+ L ++NRE QY++ ++ D+ + SGT V I++ +
Sbjct: 207 PYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTD 261
Query: 369 MNDEPP 374
+ND PP
Sbjct: 262 VNDNPP 267
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/263 (26%), Positives = 110/263 (41%), Gaps = 33/263 (12%)
Query: 136 PFPLDSINVTEKKSVGEIIARVKATDRDEDS-----SIIYSFKTQQKMFCLDPFTGTITL 190
P + + +V E VG + +V ATD D+ S +IYS Q F ++P TG I
Sbjct: 161 PEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRT 220
Query: 191 LQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVI 250
P N+ N N + Y + +A D G + T TV
Sbjct: 221 ALP-NM-NRENREQYQVVIQAKDMGGQMGGLSGTT----------------------TVN 256
Query: 251 VRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN-NMEYTVVGGNLGTP 309
+ ++ +N+ P + V E+SPV T +G V TDAD N +EY ++ G+
Sbjct: 257 ITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDM 316
Query: 310 PKFYIEPDT--GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVL 367
E DT G+I + L+ E Y + V+ + D L T V IS+
Sbjct: 317 FDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIE 376
Query: 368 NMNDEPPVCNPPHLETQIYSTVE 390
++ DEPPV + +++ +E
Sbjct: 377 DV-DEPPVFSRSSYLFEVHEDIE 398
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/250 (23%), Positives = 108/250 (43%), Gaps = 43/250 (17%)
Query: 137 FPLDSIN--VTEKKSVGEIIARVKATDRDEDSSIIYSFKTQQ----KMFCL----DPFTG 186
FP ++I+ V E VG I VKATD D + ++ MF + D G
Sbjct: 269 FPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEG 328
Query: 187 TITLLQPLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAI 246
IT+ +PL+ ++ ++Y+L+ EA + + Y F +
Sbjct: 329 IITVKKPLDYES---RRLYTLKVEAENTHVDPRFYYLGPFKD------------------ 367
Query: 247 ITVIVRVSRINELN--PIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGG 304
T IV++S I +++ P+ S S++ F V E+ V T++G V D D + + ++ +
Sbjct: 368 -TTIVKIS-IEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFS-LDR 424
Query: 305 NLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTI 364
+ F I G + L+RE+ + + V +++N + + V +
Sbjct: 425 HTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNP-------KETTRVAVFV 477
Query: 365 SVLNMNDEPP 374
+L++ND P
Sbjct: 478 RILDVNDNAP 487
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 70.1 bits (170), Expect = 4e-12
Identities = 48/139 (34%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 251 VRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWP---FNNMEYTVVGGNLG 307
++V IN+ P+ + F SV E S TLV K+ TDAD P + + Y +V
Sbjct: 147 IKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPA 206
Query: 308 TPPKFYIEPDTGVIKLLD-SLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISV 366
PP FY+ DTG I +L+RE S Y + V+ D + + P++Q AQV I +
Sbjct: 207 YPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQ----AQVQIRI 262
Query: 367 LNMNDEPPVCNPPHLETQI 385
L++ND PV LE +
Sbjct: 263 LDVNDNIPVVENKVLEGMV 281
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 70.1 bits (170), Expect = 4e-12
Identities = 77/283 (27%), Positives = 120/283 (42%), Gaps = 47/283 (16%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSF---KTQQKMFCLDPFTGTITLLQPLNLD 197
++++ E S G + +V ATD D + ++ F LD TG +T+++ L+ +
Sbjct: 504 TVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDRE 563
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
Y A DNG + TVFV +D N
Sbjct: 564 KEDK---YLFTILAKDNGVPPLTSNVTVFVSIIDQ------------------------N 596
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPD 317
+ +P+ + + + F V EN P VG +T TD D+ N+ V L F I+
Sbjct: 597 DNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS---AVTLSILDENDDFTIDSQ 653
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV-C 376
TGVI+ S +RE + Y VK D + RS +A+VTI+V+++ND PV
Sbjct: 654 TGVIRPNISFDREKQESYTFYVKAEDGGRVS-------RSSSAKVTINVVDVNDNKPVFI 706
Query: 377 NPPH---LETQIYSTVESFHSAQLFSKDSP---QEHLSYSIVG 413
PP+ E + ST Q+ + D+ + YSIVG
Sbjct: 707 VPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG 749
Score = 57.4 bits (137), Expect = 3e-08
Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 36/248 (14%)
Query: 140 DSINVTEKKSVGEIIARVKATDRDED-SSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
D++ ++E + IA + TD+D D + + F + F L P LL+ +
Sbjct: 398 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 457
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
++K Y+++ A D G + + +F++ D+ N+
Sbjct: 458 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE------------------------ND 493
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDT 318
P+ + S T S+ EN+ + KV+ TDAD N ++G + PP+F ++ T
Sbjct: 494 NAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD--APPEFSLDRRT 551
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G++ ++ L+RE E +Y + D + +P PL + V +S+++ ND PV
Sbjct: 552 GMLTVVKKLDREKEDKYLFTILAKD---NGVP-PL---TSNVTVFVSIIDQNDNSPVFT- 603
Query: 379 PHLETQIY 386
H E + Y
Sbjct: 604 -HNEYKFY 610
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/260 (21%), Positives = 108/260 (41%), Gaps = 37/260 (14%)
Query: 137 FPLDSINVT--EKKSVGEIIARVKATDRDEDSSIIYSFKT--QQKMFCLDPFTGTITLLQ 192
FP IN++ E ++ A D D + + +++ Q +F LD
Sbjct: 171 FPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDV--------- 221
Query: 193 PLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVR 252
++ P K+ L + + +Y V VE D F ++ + V
Sbjct: 222 ---IETPEGDKMPQLIVQKELDREEKDTYVMKVKVE--------DGGFPQRSSTAILQVS 270
Query: 253 VSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN---NMEYTVVGGNLGTP 309
V+ N+ +P+ + S+ EN+PV T V ++ TDAD N + ++ + N+
Sbjct: 271 VTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIAR- 329
Query: 310 PKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNM 369
F++ TG+I + + L+RE +K+ V + D +P A V ++V ++
Sbjct: 330 RLFHLNATTGLITIKEPLDREETPNHKLLVLAS--DGGLMP-------ARAMVLVNVTDV 380
Query: 370 NDEPPVCNPPHLETQIYSTV 389
ND P + ++ + TV
Sbjct: 381 NDNVPSIDIRYIVNPVNDTV 400
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 23/178 (12%)
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME------- 298
++ + + IN+ P+ A+ S+ ENS +++ D D N ++
Sbjct: 154 LVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS 213
Query: 299 YTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSG 358
+ G ++ P+ P V K LD RE + Y + VKV D QRS
Sbjct: 214 QNIFGLDVIETPEGDKMPQLIVQKELD---REEKDTYVMKVKVED-------GGFPQRSS 263
Query: 359 TAQVTISVLNMNDEPPVCNPPHLETQI------YSTVESFHSAQLFSKDSPQEHLSYS 410
TA + +SV + ND PV +E I ++V H+ ++ + H S+S
Sbjct: 264 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 321
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 70.1 bits (170), Expect = 4e-12
Identities = 77/283 (27%), Positives = 120/283 (42%), Gaps = 47/283 (16%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSF---KTQQKMFCLDPFTGTITLLQPLNLD 197
++++ E S G + +V ATD D + ++ F LD TG +T+++ L+ +
Sbjct: 504 TVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDRE 563
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
Y A DNG + TVFV +D N
Sbjct: 564 KEDK---YLFTILAKDNGVPPLTSNVTVFVSIIDQ------------------------N 596
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPD 317
+ +P+ + + + F V EN P VG +T TD D+ N+ V L F I+
Sbjct: 597 DNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS---AVTLSILDENDDFTIDSQ 653
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV-C 376
TGVI+ S +RE + Y VK D + RS +A+VTI+V+++ND PV
Sbjct: 654 TGVIRPNISFDREKQESYTFYVKAEDGGRVS-------RSSSAKVTINVVDVNDNKPVFI 706
Query: 377 NPPH---LETQIYSTVESFHSAQLFSKDSP---QEHLSYSIVG 413
PP+ E + ST Q+ + D+ + YSIVG
Sbjct: 707 VPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG 749
Score = 57.4 bits (137), Expect = 3e-08
Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 36/248 (14%)
Query: 140 DSINVTEKKSVGEIIARVKATDRDED-SSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
D++ ++E + IA + TD+D D + + F + F L P LL+ +
Sbjct: 398 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 457
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
++K Y+++ A D G + + +F++ D+ N+
Sbjct: 458 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE------------------------ND 493
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDT 318
P+ + S T S+ EN+ + KV+ TDAD N ++G + PP+F ++ T
Sbjct: 494 NAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD--APPEFSLDRRT 551
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G++ ++ L+RE E +Y + D + +P PL + V +S+++ ND PV
Sbjct: 552 GMLTVVKKLDREKEDKYLFTILAKD---NGVP-PL---TSNVTVFVSIIDQNDNSPVFT- 603
Query: 379 PHLETQIY 386
H E + Y
Sbjct: 604 -HNEYKFY 610
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/260 (21%), Positives = 108/260 (41%), Gaps = 37/260 (14%)
Query: 137 FPLDSINVT--EKKSVGEIIARVKATDRDEDSSIIYSFKT--QQKMFCLDPFTGTITLLQ 192
FP IN++ E ++ A D D + + +++ Q +F LD
Sbjct: 171 FPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDV--------- 221
Query: 193 PLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVR 252
++ P K+ L + + +Y V VE D F ++ + V
Sbjct: 222 ---IETPEGDKMPQLIVQKELDREEKDTYVMKVKVE--------DGGFPQRSSTAILQVS 270
Query: 253 VSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN---NMEYTVVGGNLGTP 309
V+ N+ +P+ + S+ EN+PV T V ++ TDAD N + ++ + N+
Sbjct: 271 VTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIAR- 329
Query: 310 PKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNM 369
F++ TG+I + + L+RE +K+ V + D +P A V ++V ++
Sbjct: 330 RLFHLNATTGLITIKEPLDREETPNHKLLVLAS--DGGLMP-------ARAMVLVNVTDV 380
Query: 370 NDEPPVCNPPHLETQIYSTV 389
ND P + ++ + TV
Sbjct: 381 NDNVPSIDIRYIVNPVNDTV 400
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 23/178 (12%)
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME------- 298
++ + + IN+ P+ A+ S+ ENS +++ D D N ++
Sbjct: 154 LVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS 213
Query: 299 YTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSG 358
+ G ++ P+ P V K LD RE + Y + VKV D QRS
Sbjct: 214 QNIFGLDVIETPEGDKMPQLIVQKELD---REEKDTYVMKVKVED-------GGFPQRSS 263
Query: 359 TAQVTISVLNMNDEPPVCNPPHLETQI------YSTVESFHSAQLFSKDSPQEHLSYS 410
TA + +SV + ND PV +E I ++V H+ ++ + H S+S
Sbjct: 264 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 321
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 70.1 bits (170), Expect = 4e-12
Identities = 77/283 (27%), Positives = 120/283 (42%), Gaps = 47/283 (16%)
Query: 141 SINVTEKKSVGEIIARVKATDRDEDSSIIYSF---KTQQKMFCLDPFTGTITLLQPLNLD 197
++++ E S G + +V ATD D + ++ F LD TG +T+++ L+ +
Sbjct: 493 TVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDRE 552
Query: 198 NPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRIN 257
Y A DNG + TVFV +D N
Sbjct: 553 KEDK---YLFTILAKDNGVPPLTSNVTVFVSIIDQ------------------------N 585
Query: 258 ELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPD 317
+ +P+ + + + F V EN P VG +T TD D+ N+ V L F I+
Sbjct: 586 DNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS---AVTLSILDENDDFTIDSQ 642
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV-C 376
TGVI+ S +RE + Y VK D + RS +A+VTI+V+++ND PV
Sbjct: 643 TGVIRPNISFDREKQESYTFYVKAEDGGRVS-------RSSSAKVTINVVDVNDNKPVFI 695
Query: 377 NPPH---LETQIYSTVESFHSAQLFSKDSP---QEHLSYSIVG 413
PP+ E + ST Q+ + D+ + YSIVG
Sbjct: 696 VPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG 738
Score = 57.4 bits (137), Expect = 3e-08
Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 36/248 (14%)
Query: 140 DSINVTEKKSVGEIIARVKATDRDED-SSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
D++ ++E + IA + TD+D D + + F + F L P LL+ +
Sbjct: 387 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 446
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
++K Y+++ A D G + + +F++ D+ N+
Sbjct: 447 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE------------------------ND 482
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIEPDT 318
P+ + S T S+ EN+ + KV+ TDAD N ++G + PP+F ++ T
Sbjct: 483 NAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD--APPEFSLDRRT 540
Query: 319 GVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNP 378
G++ ++ L+RE E +Y + D + +P PL + V +S+++ ND PV
Sbjct: 541 GMLTVVKKLDREKEDKYLFTILAKD---NGVP-PL---TSNVTVFVSIIDQNDNSPVFT- 592
Query: 379 PHLETQIY 386
H E + Y
Sbjct: 593 -HNEYKFY 599
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/260 (21%), Positives = 108/260 (41%), Gaps = 37/260 (14%)
Query: 137 FPLDSINVT--EKKSVGEIIARVKATDRDEDSSIIYSFKT--QQKMFCLDPFTGTITLLQ 192
FP IN++ E ++ A D D + + +++ Q +F LD
Sbjct: 160 FPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDV--------- 210
Query: 193 PLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVR 252
++ P K+ L + + +Y V VE D F ++ + V
Sbjct: 211 ---IETPEGDKMPQLIVQKELDREEKDTYVMKVKVE--------DGGFPQRSSTAILQVS 259
Query: 253 VSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN---NMEYTVVGGNLGTP 309
V+ N+ +P+ + S+ EN+PV T V ++ TDAD N + ++ + N+
Sbjct: 260 VTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIAR- 318
Query: 310 PKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNM 369
F++ TG+I + + L+RE +K+ V + D +P A V ++V ++
Sbjct: 319 RLFHLNATTGLITIKEPLDREETPNHKLLVLAS--DGGLMP-------ARAMVLVNVTDV 369
Query: 370 NDEPPVCNPPHLETQIYSTV 389
ND P + ++ + TV
Sbjct: 370 NDNVPSIDIRYIVNPVNDTV 389
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 23/178 (12%)
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME------- 298
++ + + IN+ P+ A+ S+ ENS +++ D D N ++
Sbjct: 143 LVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS 202
Query: 299 YTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSG 358
+ G ++ P+ P V K LD RE + Y + VKV D QRS
Sbjct: 203 QNIFGLDVIETPEGDKMPQLIVQKELD---REEKDTYVMKVKVED-------GGFPQRSS 252
Query: 359 TAQVTISVLNMNDEPPVCNPPHLETQI------YSTVESFHSAQLFSKDSPQEHLSYS 410
TA + +SV + ND PV +E I ++V H+ ++ + H S+S
Sbjct: 253 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 310
>gi|16507964 cadherin-like 23 isoform 2 precursor [Homo sapiens]
Length = 530
Score = 70.1 bits (170), Expect = 4e-12
Identities = 65/264 (24%), Positives = 117/264 (44%), Gaps = 37/264 (14%)
Query: 141 SINVTEKKSVGEIIARVKATDRD--EDSSIIYSFKTQQKMFCLDPFTGTITLLQPLNLDN 198
S+ + E VG I V ATD D S++YSF+ + F +D G +T+++ L+ +
Sbjct: 138 SVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYE- 196
Query: 199 PSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINE 258
++ Y L ATD ++ P+S + + + ++ + +
Sbjct: 197 --TTQAYQLTVNATD--------------QDKTRPLS---------TLANLAIIITDVQD 231
Query: 259 LNPIGSASAFTFSVFENSPVDTLVGKVTFTDAD-WPFNNMEYTVVGGNLGTPPKFYIEPD 317
++PI ++ +++E+SP T V +T D D + YT+V GN T F ++
Sbjct: 232 MDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGN--TNSIFALDYI 289
Query: 318 TGVIKLLDSLNRE---IESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPP 374
+GV+ L L+RE + + VK T+L++D P + T I V+++ND P
Sbjct: 290 SGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPS---DATVTTTFNILVIDINDNAP 346
Query: 375 VCNPPHLETQIYSTVESFHSAQLF 398
N I + + LF
Sbjct: 347 EFNSSEYSVAITELAQVGFALPLF 370
Score = 53.1 bits (126), Expect = 6e-07
Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 50/249 (20%)
Query: 144 VTEKKSVGEIIARVKATDRDEDSSII-YSFKTQQKMFCLDPFTGTITLLQPLNLDNPSNS 202
++E VG + ++ A D D D + S + + F ++P TG + L QPL+ + S
Sbjct: 42 ISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSE- 100
Query: 203 KIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVRVSRINELNPI 262
+++E +D+ G V ++V +N+ P
Sbjct: 101 --FTVEFSVSDH---------------------------QGVITRKVNIQVGDVNDNAPT 131
Query: 263 GSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNL---GTPPK--FYIEPD 317
++ + EN+PV T + V TD D GG++ PP F I+
Sbjct: 132 FHNQPYSVRIPENTPVGTPIFIVNATDPD--------LGAGGSVLYSFQPPSQFFAIDSA 183
Query: 318 TGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCN 377
G++ ++ L+ E Y++ V TD D R S A + I + ++ D P+
Sbjct: 184 RGIVTVIRELDYETTQAYQLTVNATD------QDKTRPLSTLANLAIIITDVQDMDPIFI 237
Query: 378 PPHLETQIY 386
T IY
Sbjct: 238 NLPYSTNIY 246
Score = 38.1 bits (87), Expect = 0.019
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 21/117 (17%)
Query: 272 VFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFY-IEPDTGVIKLLDSLNRE 330
+ E++PV + V ++ D D + V G + +F+ +EPDTGV+ L L+RE
Sbjct: 42 ISEDTPVGSSVTQLLAQDMD-----NDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRE 96
Query: 331 IESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPVCNPPHLETQIYS 387
+S++ + V+D Q T +V I V ++ND N P Q YS
Sbjct: 97 TKSEFTVEFSVSD----------HQGVITRKVNIQVGDVND-----NAPTFHNQPYS 138
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 69.3 bits (168), Expect = 8e-12
Identities = 109/465 (23%), Positives = 192/465 (41%), Gaps = 65/465 (13%)
Query: 3 MGSKLKCEHDTNGKVEPHAADNHFQGAGLGPN------QIMAGSGVITATKIFNYETDPI 56
+G+ + H T+ + +A HF + L N + A +G+IT + + E P
Sbjct: 264 VGTSVTQLHATDADIGENAKI-HFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPN 322
Query: 57 RFLLIV--DTGRL-YRHVLTINIIDVPES-PNCTADPKFSSGTATLEIDEDYPLFQSIYR 112
LL++ D G + R ++ +N+ DV ++ P+ + T+ + E+ PL I
Sbjct: 323 HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIAL 382
Query: 113 VTATDEVFANGDRLNVGGDH---------CARPFPLDSINVTEKKSVGEIIARVKATDRD 163
+T TD+ + R+ DH + F L++ + +S E ++ A D
Sbjct: 383 ITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAG 442
Query: 164 E---DSSIIYSFKTQQKMFCLDPFTGT---------------ITLLQPLNLDNPSNSKI- 204
+ + S + K + + FT + +T + ++ D+ N+KI
Sbjct: 443 KPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKIN 502
Query: 205 YSLETEATDNGNNTSSYTFTVFVENVDDP---------ISCDPSFSTGAAIITVIVRVSR 255
Y L +A + V+ +D ++ D + +TV V +
Sbjct: 503 YLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 562
Query: 256 INELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNMEYTVVGGNLGTPPKFYIE 315
N+ +P+ + + + F V EN P VG +T TD D+ N+ V L F I+
Sbjct: 563 QNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS---AVTLSILDENDDFTID 619
Query: 316 PDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNMNDEPPV 375
TGVI+ S +RE + Y VK D + RS +A+VTI+V+++ND PV
Sbjct: 620 SQTGVIRPNISFDREKQESYTFYVKAEDGGRVS-------RSSSAKVTINVVDVNDNKPV 672
Query: 376 CNPP----HLETQIYSTVESFHSAQLFSKDSP---QEHLSYSIVG 413
P E + ST Q+ + D+ + YSIVG
Sbjct: 673 FIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVG 717
Score = 48.5 bits (114), Expect = 1e-05
Identities = 57/260 (21%), Positives = 108/260 (41%), Gaps = 37/260 (14%)
Query: 137 FPLDSINVT--EKKSVGEIIARVKATDRDEDSSIIYSFKT--QQKMFCLDPFTGTITLLQ 192
FP IN++ E ++ A D D + + +++ Q +F LD
Sbjct: 139 FPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDV--------- 189
Query: 193 PLNLDNPSNSKIYSLETEATDNGNNTSSYTFTVFVENVDDPISCDPSFSTGAAIITVIVR 252
++ P K+ L + + +Y V VE D F ++ + V
Sbjct: 190 ---IETPEGDKMPQLIVQKELDREEKDTYVMKVKVE--------DGGFPQRSSTAILQVS 238
Query: 253 VSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFN---NMEYTVVGGNLGTP 309
V+ N+ +P+ + S+ EN+PV T V ++ TDAD N + ++ + N+
Sbjct: 239 VTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIAR- 297
Query: 310 PKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSGTAQVTISVLNM 369
F++ TG+I + + L+RE +K+ V + D +P A V ++V ++
Sbjct: 298 RLFHLNATTGLITIKEPLDREETPNHKLLVLAS--DGGLMP-------ARAMVLVNVTDV 348
Query: 370 NDEPPVCNPPHLETQIYSTV 389
ND P + ++ + TV
Sbjct: 349 NDNVPSIDIRYIVNPVNDTV 368
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 23/178 (12%)
Query: 246 IITVIVRVSRINELNPIGSASAFTFSVFENSPVDTLVGKVTFTDADWPFNNME------- 298
++ + + IN+ P+ A+ S+ ENS +++ D D N ++
Sbjct: 122 LVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKS 181
Query: 299 YTVVGGNLGTPPKFYIEPDTGVIKLLDSLNREIESQYKIAVKVTDLDNDAIPDPLRQRSG 358
+ G ++ P+ P V K LD RE + Y + VKV D QRS
Sbjct: 182 QNIFGLDVIETPEGDKMPQLIVQKELD---REEKDTYVMKVKVED-------GGFPQRSS 231
Query: 359 TAQVTISVLNMNDEPPVCNPPHLETQI------YSTVESFHSAQLFSKDSPQEHLSYS 410
TA + +SV + ND PV +E I ++V H+ ++ + H S+S
Sbjct: 232 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,361,814
Number of Sequences: 37866
Number of extensions: 863042
Number of successful extensions: 2831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 110
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 1408
Number of HSP's gapped (non-prelim): 960
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.