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Search of human proteins with 23943872
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23943872 small ArfGAP2 [Homo sapiens]
(429 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23943872 small ArfGAP2 [Homo sapiens] 874 0.0
gi|21264558 stromal membrane-associated GTPase-activating protei... 368 e-102
gi|113204622 stromal membrane-associated GTPase-activating prote... 362 e-100
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 100 2e-21
gi|7661880 centaurin beta1 [Homo sapiens] 100 3e-21
gi|187608516 centaurin, beta 2 [Homo sapiens] 100 4e-21
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 97 4e-20
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 97 4e-20
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 95 1e-19
gi|6806913 centaurin, alpha 1 [Homo sapiens] 95 1e-19
gi|8923763 centaurin-alpha 2 protein [Homo sapiens] 94 2e-19
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 91 2e-18
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 90 3e-18
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 90 3e-18
gi|46094081 development and differentiation enhancing factor 1 [... 89 1e-17
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 88 1e-17
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 88 1e-17
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 88 1e-17
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 88 1e-17
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 87 3e-17
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 86 5e-17
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 86 5e-17
gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ... 85 1e-16
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 82 7e-16
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 82 7e-16
gi|214829673 ADP-ribosylation factor GTPase activating protein 3... 81 2e-15
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 79 8e-15
gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 77 3e-14
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ... 76 7e-14
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i... 76 7e-14
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 874 bits (2259), Expect = 0.0
Identities = 429/429 (100%), Positives = 429/429 (100%)
Query: 1 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGV 60
MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGV
Sbjct: 1 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGV 60
Query: 61 HISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEK 120
HISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEK
Sbjct: 61 HISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEK 120
Query: 121 KKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS 180
KKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS
Sbjct: 121 KKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS 180
Query: 181 TAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGS 240
TAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGS
Sbjct: 181 TAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGS 240
Query: 241 VPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSF 300
VPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSF
Sbjct: 241 VPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSF 300
Query: 301 PGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQA 360
PGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQA
Sbjct: 301 PGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQA 360
Query: 361 GYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAAN 420
GYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAAN
Sbjct: 361 GYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAAN 420
Query: 421 QTLSPQMWK 429
QTLSPQMWK
Sbjct: 421 QTLSPQMWK 429
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 368 bits (944), Expect = e-102
Identities = 215/444 (48%), Positives = 278/444 (62%), Gaps = 30/444 (6%)
Query: 4 KSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHIS 63
K+ K +++Q +L+ LL EEDNK+CADC++KGPRWASWNIGVFICIRCAGIHRNLGVHIS
Sbjct: 9 KAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHIS 68
Query: 64 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY 123
RVKSVNLDQWT EQIQCMQ+MGN KA LYEA LPE FRRPQ D AVE FIRDKYEKKKY
Sbjct: 69 RVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKY 128
Query: 124 MDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKS-SPKSTA 182
D++ ++++ K ++ E PEK +P+ EK+ QKK+ P+KS SPK A
Sbjct: 129 YDKNAIAITNKEKEKKKEEKKREKEPEKPAKPLTAEKL---QKKDQQLEPKKSTSPKKAA 185
Query: 183 -PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL---LASVPSPSS-SGSRKVVGSMPTAG 236
P +DLLGLD P + N T+ L DLD+ + S P P++ + S P A
Sbjct: 186 EPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAA 245
Query: 237 SAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQT-PQMPTQAMFMAPAQMAY- 293
+ +V +L+LF E +KSEE+ KKQLSKDSILSLYG+ T Q T +FM P + +
Sbjct: 246 TLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT 305
Query: 294 ---PTAYPSFPGVTPPNSIMGSMMPPPVGMV--AQPGASGMVAPMAMPAGYMGGMQASMM 348
P A+ FP MG +P G++ + M+ M MP G+MG Q +M
Sbjct: 306 SQAPAAFQGFPS-------MGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVM 358
Query: 349 GVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYG 408
+P ++ Q G M G PQ+ +G+ AQQ QW+L+QM QQMAGM+ A +G
Sbjct: 359 PLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFG 416
Query: 409 QSMS---GGNGQAANQTLSPQMWK 429
Q S G +G ++ QTLS Q+WK
Sbjct: 417 QPSSTTAGWSGSSSGQTLSTQLWK 440
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 362 bits (928), Expect = e-100
Identities = 220/471 (46%), Positives = 281/471 (59%), Gaps = 57/471 (12%)
Query: 4 KSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHIS 63
K+ K +++Q +L+ LL EEDNK+CADC++KGPRWASWNIGVFICIRCAGIHRNLGVHIS
Sbjct: 9 KAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHIS 68
Query: 64 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY 123
RVKSVNLDQWT EQIQCMQ+MGN KA LYEA LPE FRRPQ D AVE FIRDKYEKKKY
Sbjct: 69 RVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKY 128
Query: 124 MDR--------------------------SLDINAFRKEKD-DKWKRGSEPVPEKKLEPV 156
D+ ++D N KEK+ K ++ E PEK +P+
Sbjct: 129 YDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAKPL 188
Query: 157 VFEKVKMPQKKEDPQLPRKS-SPKSTA-PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL 213
EK+ QKK+ P+KS SPK A P +DLLGLD P + N T+ L DLD+
Sbjct: 189 TAEKL---QKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDI 245
Query: 214 ---LASVPSPSS-SGSRKVVGSMPTAGSAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSI 268
+ S P P++ + S P A + +V +L+LF E +KSEE+ KKQLSKDSI
Sbjct: 246 FGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSI 305
Query: 269 LSLYGSQT-PQMPTQAMFMAPAQMAY----PTAYPSFPGVTPPNSIMGSMMPPPVGMV-- 321
LSLYG+ T Q T +FM P + + P A+ FP MG +P G++
Sbjct: 306 LSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPS-------MGVPVPAAPGLIGN 358
Query: 322 AQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQ 381
+ M+ M MP G+MG Q +M +P ++ Q G M G PQ+ +G+ AQQ
Sbjct: 359 VMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQ 416
Query: 382 LQWNLTQMTQQMAGMNFYGANGMMNYGQSMS---GGNGQAANQTLSPQMWK 429
QW+L+QM QQMAGM+ A +GQ S G +G ++ QTLS Q+WK
Sbjct: 417 PQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 467
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 100 bits (250), Expect = 2e-21
Identities = 49/119 (41%), Positives = 73/119 (61%), Gaps = 4/119 (3%)
Query: 13 QAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ 72
++VL + N C DC PRWAS N+GV +CI C+GIHR+LGVH S+V+S+ LD
Sbjct: 403 ESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDS 462
Query: 73 WTQEQIQCMQEMGNGKANRLYEAYLPET-FRRPQIDPA---VEGFIRDKYEKKKYMDRS 127
W E ++ M E+GN N++YEA R+P + E +I+DKY +KK++ ++
Sbjct: 463 WEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKA 521
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 100 bits (249), Expect = 3e-21
Identities = 55/142 (38%), Positives = 82/142 (57%), Gaps = 8/142 (5%)
Query: 15 VLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 74
V+A + + N C DC+ P WAS N+GV +CI+C+GIHR+LGVH S+V+S+ LD W
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
Query: 75 QEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV-----EGFIRDKYEKKKYMDRSLD 129
E ++ M E+GN N++YEA + E + P+ E +I KY +KK++ + +
Sbjct: 467 PELVKLMCELGNVIINQIYEARV-EAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPE 525
Query: 130 INAFRKEKDDKWKRGSEPVPEK 151
I R + RG PVP K
Sbjct: 526 IRGRRGGRGR--PRGQPPVPPK 545
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 99.8 bits (247), Expect = 4e-21
Identities = 54/133 (40%), Positives = 83/133 (62%), Gaps = 8/133 (6%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC PRWAS N+G+ +CI C+GIHR+LGVH S+V+S+ LD W E ++ M E+
Sbjct: 411 NASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCEL 470
Query: 85 GNGKANRLYEAYLPET-FRRPQID--PAVEGFIRDKYEKKKYMDR-SLDINAFRKEKDDK 140
GN NR+YEA + + ++PQ E +IR KY ++K++D+ S+ ++ ++K
Sbjct: 471 GNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQK--- 527
Query: 141 WKRGSEPVPEKKL 153
K S+ EK+L
Sbjct: 528 -KFVSKSSEEKRL 539
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 96.7 bits (239), Expect = 4e-20
Identities = 45/103 (43%), Positives = 66/103 (64%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P WAS N+G +CI C+GIHRNLG H+SRV+S++LD W E I+ M +
Sbjct: 568 NSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSI 627
Query: 85 GNGKANRLYEAYLPETFRRPQIDPA---VEGFIRDKYEKKKYM 124
GN AN ++E + +P +D E +IR KYE+K ++
Sbjct: 628 GNELANSVWEE-SSQGRTKPSVDSTREEKERWIRAKYEQKLFL 669
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 96.7 bits (239), Expect = 4e-20
Identities = 45/103 (43%), Positives = 66/103 (64%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P WAS N+G +CI C+GIHRNLG H+SRV+S++LD W E I+ M +
Sbjct: 621 NSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSI 680
Query: 85 GNGKANRLYEAYLPETFRRPQIDPA---VEGFIRDKYEKKKYM 124
GN AN ++E + +P +D E +IR KYE+K ++
Sbjct: 681 GNELANSVWEE-SSQGRTKPSVDSTREEKERWIRAKYEQKLFL 722
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 95.1 bits (235), Expect = 1e-19
Identities = 46/103 (44%), Positives = 64/103 (62%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N FC DC + P WAS N+G +CI C+GIHR+LG H+SRV+S++LD W E + M M
Sbjct: 674 NSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAM 733
Query: 85 GNGKANRLYEAYLPETFRRPQIDPA---VEGFIRDKYEKKKYM 124
GN AN ++E L + +P D E +IR KYE+K ++
Sbjct: 734 GNALANSVWEGAL-GGYSKPGPDACREEKERWIRAKYEQKLFL 775
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 94.7 bits (234), Expect = 1e-19
Identities = 56/142 (39%), Positives = 82/142 (57%), Gaps = 8/142 (5%)
Query: 10 DRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 69
+R +AVL LL N CADC + P WAS+ +GVFIC+ C+GIHRN+ +S+VKSV
Sbjct: 4 ERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
Query: 70 LDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV---EGFIRDKYEKKK--YM 124
LD W + Q++ M GN A +E+ +P + RP E +IR KYE+++ Y
Sbjct: 62 LDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
Query: 125 DRSLDINAFRKEKDDKWKRGSE 146
++ +A +E WKRG +
Sbjct: 122 EKQEPYSAGYRE-GFLWKRGRD 142
>gi|8923763 centaurin-alpha 2 protein [Homo sapiens]
Length = 381
Score = 94.4 bits (233), Expect = 2e-19
Identities = 54/144 (37%), Positives = 78/144 (54%), Gaps = 6/144 (4%)
Query: 8 DVDRYQAVLANLLLEED--NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRV 65
D +R + L LL D N CADC + P WAS+ +G+FIC+ C G+HRN ISRV
Sbjct: 3 DRERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNF-PDISRV 61
Query: 66 KSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV---EGFIRDKYEKKK 122
KSV LD W ++ M GN + +EA +P + PQ + + E +IR KYE+++
Sbjct: 62 KSVRLDFWDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERRE 121
Query: 123 YMDRSLDINAFRKEKDDKWKRGSE 146
+M I+ + WKRG +
Sbjct: 122 FMADGETISLPGNREGFLWKRGRD 145
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 90.9 bits (224), Expect = 2e-18
Identities = 43/103 (41%), Positives = 64/103 (62%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIHR+LG +SRV+S+ LD W E + M +
Sbjct: 340 NSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSI 399
Query: 85 GNGKANRLYEAYLPETFRRPQIDPA---VEGFIRDKYEKKKYM 124
GN AN ++E + +P I+ E +IR KYE K ++
Sbjct: 400 GNDLANSIWEG-SSQGQTKPSIESTREEKERWIRSKYEHKLFL 441
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 90.1 bits (222), Expect = 3e-18
Identities = 43/102 (42%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC + P WAS N+G ICI C+GIHRNLG H+SRV+S++LD W +E + +
Sbjct: 943 NSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAI 1002
Query: 85 GNGKANRLYEAYLPETFR--RPQIDPAVEGFIRDKYEKKKYM 124
GN ANR++E+ + R E +IR KYE+ ++
Sbjct: 1003 GNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFL 1044
Score = 31.2 bits (69), Expect = 1.9
Identities = 40/159 (25%), Positives = 61/159 (38%), Gaps = 15/159 (9%)
Query: 195 ACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSK 254
A ++ T+ + L L SVP P S S G+ GS P + EPG K
Sbjct: 5 AGALQRRTTTYLISLTLVKLESVPPPPPSPSAAAAGAAGARGSETGDPGSPRGAEEPGKK 64
Query: 255 SEEIGKKQLSKDSI-LSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSM 313
E + +D++ +S + T A+ APA A P V+P S+
Sbjct: 65 RHE--RLFHRQDALWISTSSAGTGGAEPPALSPAPASPARP--------VSPAPGRRLSL 114
Query: 314 MPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPN 352
P G P SG ++P P G + ++ P+
Sbjct: 115 WAVPPG----PPLSGGLSPDPKPGGAPTSSRRPLLSSPS 149
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 90.1 bits (222), Expect = 3e-18
Identities = 43/102 (42%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC + P WAS N+G ICI C+GIHRNLG H+SRV+S++LD W +E + +
Sbjct: 587 NSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAI 646
Query: 85 GNGKANRLYEAYLPETFR--RPQIDPAVEGFIRDKYEKKKYM 124
GN ANR++E+ + R E +IR KYE+ ++
Sbjct: 647 GNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFL 688
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 88.6 bits (218), Expect = 1e-17
Identities = 42/116 (36%), Positives = 66/116 (56%), Gaps = 2/116 (1%)
Query: 10 DRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 69
D +A++ ++ N C DC S P W S N+G+ CI C+GIHR +GVHISR++S+
Sbjct: 436 DLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLE 495
Query: 70 LDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMD 125
LD+ ++ + +GN N + EA LP +P P+ + +R +Y KY+D
Sbjct: 496 LDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKP--TPSSDMTVRKEYITAKYVD 549
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 88.2 bits (217), Expect = 1e-17
Identities = 42/103 (40%), Positives = 63/103 (61%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIHR+ G +SRV+S+ LD W E + M +
Sbjct: 476 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSI 535
Query: 85 GNGKANRLYEAYLPETFRRPQIDPA---VEGFIRDKYEKKKYM 124
GN AN ++E + +P I E +IR KYE+K ++
Sbjct: 536 GNELANSIWEG-SSQGQTKPSIKSTREEKEWWIRSKYEEKLFL 577
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 88.2 bits (217), Expect = 1e-17
Identities = 42/103 (40%), Positives = 63/103 (61%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIHR+ G +SRV+S+ LD W E + M +
Sbjct: 476 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSI 535
Query: 85 GNGKANRLYEAYLPETFRRPQIDPA---VEGFIRDKYEKKKYM 124
GN AN ++E + +P I E +IR KYE+K ++
Sbjct: 536 GNELANSIWEG-SSQGQTKPSIKSTREEKEWWIRSKYEEKLFL 577
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 88.2 bits (217), Expect = 1e-17
Identities = 41/102 (40%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIHR+LG +SRV+S+ LD W E + M +
Sbjct: 453 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSI 512
Query: 85 GNGKANRLYEAYLPETFR--RPQIDPAVEGFIRDKYEKKKYM 124
GN AN ++E + E +IR KYE+K ++
Sbjct: 513 GNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFL 554
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 88.2 bits (217), Expect = 1e-17
Identities = 41/102 (40%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIHR+LG +SRV+S+ LD W E + M +
Sbjct: 453 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSI 512
Query: 85 GNGKANRLYEAYLPETFR--RPQIDPAVEGFIRDKYEKKKYM 124
GN AN ++E + E +IR KYE+K ++
Sbjct: 513 GNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFL 554
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 87.0 bits (214), Expect = 3e-17
Identities = 41/102 (40%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIHR+LG H+SRV+S+ LD W E + M +
Sbjct: 476 NAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSSI 535
Query: 85 GNGKANRLYEAYLPETFR--RPQIDPAVEGFIRDKYEKKKYM 124
N AN ++E + E +IR KYE+K ++
Sbjct: 536 VNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFL 577
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 86.3 bits (212), Expect = 5e-17
Identities = 43/107 (40%), Positives = 64/107 (59%), Gaps = 12/107 (11%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C D +++ P+WAS N+GV +CI C+GIHR+LG +SRV+S+ LD W E + M +
Sbjct: 476 NAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSI 535
Query: 85 GNGKANRLYEAYLPETFRRPQIDPAV-------EGFIRDKYEKKKYM 124
GN AN ++E + Q P+V E +IR KYE+K ++
Sbjct: 536 GNDLANSIWEG-----SSQGQTKPSVKSTREEKERWIRSKYEEKLFL 577
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 86.3 bits (212), Expect = 5e-17
Identities = 40/102 (39%), Positives = 60/102 (58%), Gaps = 2/102 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84
N C DC+++ P+WAS N+GV +CI C+GIH +LG +SRV+S+ LD W E + M +
Sbjct: 453 NAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELDDWPVELRKVMSSI 512
Query: 85 GNGKANRLYEAYLPETFR--RPQIDPAVEGFIRDKYEKKKYM 124
GN AN ++E + E +IR KYE+K ++
Sbjct: 513 GNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFL 554
>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
[Homo sapiens]
Length = 521
Score = 85.1 bits (209), Expect = 1e-16
Identities = 64/232 (27%), Positives = 93/232 (40%), Gaps = 23/232 (9%)
Query: 13 QAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD- 71
Q + L NK C DC +K P WAS GVF+CI C+G+HR+LGVH+S ++S LD
Sbjct: 11 QTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDS 70
Query: 72 QWTQEQIQCMQEMGNGKANRLYEAY-LPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDI 130
W Q++CMQ GN A + + + + R+K R L
Sbjct: 71 NWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKI-------RQLGS 123
Query: 131 NAFRKEKDDKW-KRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS-TAPVMDLL 188
A + D W S VP P+KK+ + P + AP +
Sbjct: 124 AALARHGTDLWIDNMSSAVPNHS-----------PEKKDSDFFTEHTQPPAWDAPATEPS 172
Query: 189 GLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVG-SMPTAGSAG 239
G P + ++ + DLL + P S ++G P A G
Sbjct: 173 GTQQPAPSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKG 224
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 82.4 bits (202), Expect = 7e-16
Identities = 42/103 (40%), Positives = 62/103 (60%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ--WTQEQIQCMQ 82
N+FCADC + P WAS N+ V IC RCAG HR LG +S+V+S+ +D+ WT+ I+
Sbjct: 302 NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFL 361
Query: 83 EMGNGKANRLYEAYLPET-FRRPQIDPAVEG-FIRDKYEKKKY 123
++GNG NR + A +P + +P P+ + KY + KY
Sbjct: 362 QLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKY 404
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 82.4 bits (202), Expect = 7e-16
Identities = 42/103 (40%), Positives = 62/103 (60%), Gaps = 4/103 (3%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ--WTQEQIQCMQ 82
N+FCADC + P WAS N+ V IC RCAG HR LG +S+V+S+ +D+ WT+ I+
Sbjct: 547 NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFL 606
Query: 83 EMGNGKANRLYEAYLPET-FRRPQIDPAVEG-FIRDKYEKKKY 123
++GNG NR + A +P + +P P+ + KY + KY
Sbjct: 607 QLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKY 649
>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
isoform 1 [Homo sapiens]
Length = 516
Score = 81.3 bits (199), Expect = 2e-15
Identities = 51/147 (34%), Positives = 71/147 (48%), Gaps = 20/147 (13%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD-QWTQEQIQCMQE 83
NK C DC +K P WAS GVF+CI C+G HR+LGVH+S ++S LD W+ Q++CMQ
Sbjct: 22 NKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQV 81
Query: 84 MGNGKANRLYEAYLPET-FRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWK 142
GN A+ + + T + + R+K +SL A RK D W
Sbjct: 82 GGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKI-------KSLASQATRKHGTDLW- 133
Query: 143 RGSEPVPEKKLEPVVFEKVKMPQKKED 169
L+ V + P K+ED
Sbjct: 134 ----------LDSCVVPPLSPPPKEED 150
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 79.0 bits (193), Expect = 8e-15
Identities = 37/75 (49%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD-QWTQEQIQCMQE 83
NK C DC +K P WAS GVF+CI C+G HR+LGVH+S ++S LD W+ Q++CMQ
Sbjct: 22 NKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQV 81
Query: 84 MGNGKANRLYEAYLP 98
GN A L +P
Sbjct: 82 GGNASALWLDSCVVP 96
>gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
3 [Homo sapiens]
Length = 1544
Score = 77.0 bits (188), Expect = 3e-14
Identities = 44/98 (44%), Positives = 56/98 (57%), Gaps = 4/98 (4%)
Query: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQ--WTQEQIQCMQ 82
N+ CADC S P WA+ N+GV IC +CAG HR LG IS+V+S+ LD W+ E +Q
Sbjct: 501 NRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFI 560
Query: 83 EMGNGKANRLYEAYLPE-TFRRPQIDPAVEG-FIRDKY 118
+GN +ANR + LP P P G FI KY
Sbjct: 561 VLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKY 598
>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
isoform b [Homo sapiens]
Length = 414
Score = 75.9 bits (185), Expect = 7e-14
Identities = 31/85 (36%), Positives = 53/85 (62%)
Query: 11 RYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNL 70
R + VL + ++++N C +C + P+W S G++IC+ C+G HR LGVH+S V+SV +
Sbjct: 5 RTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTM 64
Query: 71 DQWTQEQIQCMQEMGNGKANRLYEA 95
D+W +++ M+ GN K E+
Sbjct: 65 DKWKDIELEKMKAGGNAKFREFLES 89
>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
Length = 406
Score = 75.9 bits (185), Expect = 7e-14
Identities = 31/85 (36%), Positives = 53/85 (62%)
Query: 11 RYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNL 70
R + VL + ++++N C +C + P+W S G++IC+ C+G HR LGVH+S V+SV +
Sbjct: 5 RTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTM 64
Query: 71 DQWTQEQIQCMQEMGNGKANRLYEA 95
D+W +++ M+ GN K E+
Sbjct: 65 DKWKDIELEKMKAGGNAKFREFLES 89
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,497,357
Number of Sequences: 37866
Number of extensions: 971941
Number of successful extensions: 4110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 245
Number of HSP's that attempted gapping in prelim test: 3608
Number of HSP's gapped (non-prelim): 727
length of query: 429
length of database: 18,247,518
effective HSP length: 105
effective length of query: 324
effective length of database: 14,271,588
effective search space: 4623994512
effective search space used: 4623994512
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.