Guide to the Human Genome
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Search of human proteins with 237681125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237681125 breast cancer 1, early onset isoform 5 [Homo
sapiens]
         (699 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]   1406   0.0  
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]   1341   0.0  
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]    828   0.0  
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]      828   0.0  
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]    820   0.0  
gi|62865604 tripartite motif protein 31 [Homo sapiens]                 65   3e-10
gi|21071052 helicase-like transcription factor [Homo sapiens]          59   2e-08
gi|21071054 helicase-like transcription factor [Homo sapiens]          59   2e-08
gi|117938316 tripartite motif-containing 22 [Homo sapiens]             58   3e-08
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...    57   6e-08
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...    56   1e-07
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...    56   1e-07
gi|30023818 tripartite motif protein 50A [Homo sapiens]                56   1e-07
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]      54   4e-07
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       54   4e-07
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]       54   4e-07
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...    54   4e-07
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...    54   4e-07
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    54   4e-07
gi|21630277 tripartite motif-containing 11 [Homo sapiens]              54   5e-07
gi|15208660 tripartite motif protein 21 [Homo sapiens]                 54   5e-07
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]    54   5e-07
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]    54   5e-07
gi|4508005 tripartite motif-containing 26 [Homo sapiens]               54   5e-07
gi|6005747 ring finger protein 2 [Homo sapiens]                        54   6e-07
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H...    54   6e-07
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]     53   1e-06
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]     53   1e-06
gi|37622899 ring finger protein 137 [Homo sapiens]                     53   1e-06
gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]           53   1e-06

>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
          Length = 699

 Score = 1406 bits (3639), Expect = 0.0
 Identities = 699/699 (100%), Positives = 699/699 (100%)

Query: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
           MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
           CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
           EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
           ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300
           PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300

Query: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360
           LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP
Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360

Query: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420
           ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS
Sbjct: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420

Query: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480
           QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA
Sbjct: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480

Query: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540
           PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE
Sbjct: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540

Query: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600
           RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF
Sbjct: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600

Query: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660
           LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL
Sbjct: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660

Query: 661 EICCYGPFTNMPTGCPPNCGCAARCLDRGQWLPCNWADV 699
           EICCYGPFTNMPTGCPPNCGCAARCLDRGQWLPCNWADV
Sbjct: 661 EICCYGPFTNMPTGCPPNCGCAARCLDRGQWLPCNWADV 699


>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
          Length = 759

 Score = 1341 bits (3470), Expect = 0.0
 Identities = 673/673 (100%), Positives = 673/673 (100%)

Query: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
           MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
           CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
           EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
           ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300
           PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300

Query: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360
           LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP
Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360

Query: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420
           ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS
Sbjct: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420

Query: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480
           QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA
Sbjct: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480

Query: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540
           PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE
Sbjct: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540

Query: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600
           RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF
Sbjct: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600

Query: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660
           LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL
Sbjct: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660

Query: 661 EICCYGPFTNMPT 673
           EICCYGPFTNMPT
Sbjct: 661 EICCYGPFTNMPT 673


>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
          Length = 1816

 Score =  828 bits (2138), Expect = 0.0
 Identities = 463/679 (68%), Positives = 508/679 (74%), Gaps = 20/679 (2%)

Query: 6    LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65
            ++ +E + V+  +       +  + +++P+ +      C      LL+  +        +
Sbjct: 1061 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1120

Query: 66   NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122
            NDI     + S  FS+ V+  EL +    F   T    A  Y   AKK  +S E+L  E 
Sbjct: 1121 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1173

Query: 123  SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182
              +    +    K  + + P   +   T  +  LS       L  K  +      V +  
Sbjct: 1174 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1231

Query: 183  GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238
             S     SE+T   A+  S    EL  +T    T+D   + S+K+   +     V  ++ 
Sbjct: 1232 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1291

Query: 239  HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295
               S+++   T   E    E+  +   GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 1292 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1351

Query: 296  TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354
            TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ
Sbjct: 1352 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1411

Query: 355  KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414
            KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ
Sbjct: 1412 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1471

Query: 415  NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474
            NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD
Sbjct: 1472 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1531

Query: 475  PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534
            PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE
Sbjct: 1532 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1591

Query: 535  LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594
            LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE
Sbjct: 1592 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1651

Query: 595  RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654
            RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR
Sbjct: 1652 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1711

Query: 655  KIFRGLEICCYGPFTNMPT 673
            KIFRGLEICCYGPFTNMPT
Sbjct: 1712 KIFRGLEICCYGPFTNMPT 1730



 Score =  436 bits (1121), Expect = e-122
 Identities = 288/538 (53%), Positives = 323/538 (60%), Gaps = 51/538 (9%)

Query: 48  MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 107
           MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF
Sbjct: 1   MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 60

Query: 108 AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 167
           AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT
Sbjct: 61  AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 120

Query: 168 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 227
           KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE
Sbjct: 121 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 180

Query: 228 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ- 285
           FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQG + S    E    +   S L  + 
Sbjct: 181 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHEN 240

Query: 286 SDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQS 345
           S +L T+ R         +  E AE     +Q G   S  +           D R P  S
Sbjct: 241 SSLLLTKDR---------MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--S 288

Query: 346 TSEKVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWY 405
           T +KV                 L+AD   +      +K K P  E    ++    D  W 
Sbjct: 289 TEKKV----------------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWI 326

Query: 406 MHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGIS 465
             + S    N  +   +EL+   D  + + E       +        D+       SG S
Sbjct: 327 TLNSSIQKVNEWFSRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSS 379

Query: 466 LFSDDPESDPSEDRAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYN 522
              D   SDP E    +S RV      S    K+      + A  P  +H T+    G  
Sbjct: 380 EKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAF 439

Query: 523 AMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580
             E  + +E+P LT       KR     SGL PE+F+     A +    + N  T +T
Sbjct: 440 VTEPQIIQERP-LTNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 492


>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score =  828 bits (2138), Expect = 0.0
 Identities = 463/679 (68%), Positives = 508/679 (74%), Gaps = 20/679 (2%)

Query: 6    LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65
            ++ +E + V+  +       +  + +++P+ +      C      LL+  +        +
Sbjct: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167

Query: 66   NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122
            NDI     + S  FS+ V+  EL +    F   T    A  Y   AKK  +S E+L  E 
Sbjct: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220

Query: 123  SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182
              +    +    K  + + P   +   T  +  LS       L  K  +      V +  
Sbjct: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278

Query: 183  GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238
             S     SE+T   A+  S    EL  +T    T+D   + S+K+   +     V  ++ 
Sbjct: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338

Query: 239  HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295
               S+++   T   E    E+  +   GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398

Query: 296  TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354
            TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ
Sbjct: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1458

Query: 355  KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414
            KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ
Sbjct: 1459 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1518

Query: 415  NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474
            NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD
Sbjct: 1519 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1578

Query: 475  PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534
            PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE
Sbjct: 1579 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1638

Query: 535  LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594
            LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE
Sbjct: 1639 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1698

Query: 595  RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654
            RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR
Sbjct: 1699 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1758

Query: 655  KIFRGLEICCYGPFTNMPT 673
            KIFRGLEICCYGPFTNMPT
Sbjct: 1759 KIFRGLEICCYGPFTNMPT 1777



 Score =  532 bits (1371), Expect = e-151
 Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%)

Query: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
           MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
           CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
           EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
           ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298
           PSNNDLNTTEKRAAERHPEKYQG + S    E    +   S L  + S +L T+ R    
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296

Query: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358
                +  E AE     +Q G   S  +           D R P  ST +KV        
Sbjct: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340

Query: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418
                    L+AD   +      +K K P  E    ++    D  W   + S    N  +
Sbjct: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386

Query: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478
              +EL+   D  + + E       +        D+       SG S   D   SDP E 
Sbjct: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439

Query: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535
              +S RV      S    K+      + A  P  +H T+    G    E  + +E+P L
Sbjct: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498

Query: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580
           T       KR     SGL PE+F+     A +    + N  T +T
Sbjct: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score =  820 bits (2117), Expect = 0.0
 Identities = 463/700 (66%), Positives = 508/700 (72%), Gaps = 41/700 (5%)

Query: 6    LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65
            ++ +E + V+  +       +  + +++P+ +      C      LL+  +        +
Sbjct: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167

Query: 66   NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122
            NDI     + S  FS+ V+  EL +    F   T    A  Y   AKK  +S E+L  E 
Sbjct: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220

Query: 123  SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182
              +    +    K  + + P   +   T  +  LS       L  K  +      V +  
Sbjct: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278

Query: 183  GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238
             S     SE+T   A+  S    EL  +T    T+D   + S+K+   +     V  ++ 
Sbjct: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338

Query: 239  HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295
               S+++   T   E    E+  +   GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398

Query: 296  TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK------ 349
            TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK      
Sbjct: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKDSHIHG 1458

Query: 350  ----------------VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS 393
                            VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS
Sbjct: 1459 QRNNSMFSKRPREHISVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS 1518

Query: 394  PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD 453
            PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD
Sbjct: 1519 PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD 1578

Query: 454  LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA 513
            LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA
Sbjct: 1579 LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA 1638

Query: 514  HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT 573
            HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT
Sbjct: 1639 HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT 1698

Query: 574  NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR 633
            NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR
Sbjct: 1699 NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR 1758

Query: 634  GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPT 673
            GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPT
Sbjct: 1759 GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPT 1798



 Score =  532 bits (1371), Expect = e-151
 Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%)

Query: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
           MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
           CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
           EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
           ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298
           PSNNDLNTTEKRAAERHPEKYQG + S    E    +   S L  + S +L T+ R    
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296

Query: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358
                +  E AE     +Q G   S  +           D R P  ST +KV        
Sbjct: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340

Query: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418
                    L+AD   +      +K K P  E    ++    D  W   + S    N  +
Sbjct: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386

Query: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478
              +EL+   D  + + E       +        D+       SG S   D   SDP E 
Sbjct: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439

Query: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535
              +S RV      S    K+      + A  P  +H T+    G    E  + +E+P L
Sbjct: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498

Query: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580
           T       KR     SGL PE+F+     A +    + N  T +T
Sbjct: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539


>gi|62865604 tripartite motif protein 31 [Homo sapiens]
          Length = 425

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 33/103 (32%), Positives = 56/103 (54%), Gaps = 11/103 (10%)

Query: 15  INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
           +N +Q+ + CPICL+++++PV+  C H FC  C+ ++     G  +CPLCK  + K ++ 
Sbjct: 7   VNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSVRKNAI- 65

Query: 75  ESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEH 117
              RF+ L+  L++ I A Q       A+     +KE   P H
Sbjct: 66  ---RFNSLLRNLVEKIQALQ-------ASEVQSKRKEATCPRH 98


>gi|21071052 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 23/53 (43%), Positives = 37/53 (69%)

Query: 23  ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75
           EC ICL+ +  PV T C H+FCK C+ +++  ++  ++CPLC+NDI + +L E
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811


>gi|21071054 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 23/53 (43%), Positives = 37/53 (69%)

Query: 23  ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75
           EC ICL+ +  PV T C H+FCK C+ +++  ++  ++CPLC+NDI + +L E
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQ----KKGPSQCPLCKNDITKRSL 73
          ++K + CPICLEL+ EP+S  C H FC+ C+   + +     +G S CP+C+      +L
Sbjct: 9  IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68

Query: 74 QESTRFSQLVEELLKI 89
          + +   + +VE + ++
Sbjct: 69 RPNRHLANIVERVKEV 84


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
          sapiens]
          Length = 493

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
          ++N  +++  CPICLEL+ +P+S  C H FC+ C+    K     KG S CP+C+     
Sbjct: 6  LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64

Query: 71 RSLQESTRFSQLVEELLKI 89
           +++ +   + LVE+L ++
Sbjct: 65 ENIRPNRHVANLVEKLREV 83


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
          sapiens]
          Length = 326

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
          ++N  +++  CPICLEL+ +P+S  C H FC+ C+    K     KG S CP+C+     
Sbjct: 6  LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64

Query: 71 RSLQESTRFSQLVEELLKI 89
           +++ +   + +VE+L ++
Sbjct: 65 ENIRPNRHVANIVEKLREV 83


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
          sapiens]
          Length = 347

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
          ++N  +++  CPICLEL+ +P+S  C H FC+ C+    K     KG S CP+C+     
Sbjct: 6  LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64

Query: 71 RSLQESTRFSQLVEELLKI 89
           +++ +   + +VE+L ++
Sbjct: 65 ENIRPNRHVANIVEKLREV 83


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 22/65 (33%), Positives = 38/65 (58%)

Query: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
          L+CPICLE+ KEP+  +C H +CK C++ L        +CP+C+  +   S   +   ++
Sbjct: 14 LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73

Query: 82 LVEEL 86
          ++E L
Sbjct: 74 VIEAL 78


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
          +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 74 QESTRFSQLVEELLKI 89
          Q +   + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
          +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 74 QESTRFSQLVEELLKI 89
          Q +   + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
          +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 74 QESTRFSQLVEELLKI 89
          Q +   + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
          sapiens]
          Length = 500

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 23/68 (33%), Positives = 40/68 (58%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q+ L CPICL+  ++PVS +C H FC+ C+ +      GP  CP C++     +L+ + 
Sbjct: 6  IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65

Query: 78 RFSQLVEE 85
            ++L E+
Sbjct: 66 ALARLTEK 73


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
          sapiens]
          Length = 474

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 23/68 (33%), Positives = 40/68 (58%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q+ L CPICL+  ++PVS +C H FC+ C+ +      GP  CP C++     +L+ + 
Sbjct: 6  IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65

Query: 78 RFSQLVEE 85
            ++L E+
Sbjct: 66 ALARLTEK 73


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18  MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
           +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422

Query: 74  QESTRFSQLVEELLKI 89
           Q +   + +VE L ++
Sbjct: 423 QANQHLANIVERLKEV 438



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 14  VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
           V+  +++ + CPICLEL+ EP+S  C H FC+ C+     + +  ++G   CP+C+    
Sbjct: 33  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 70  KRSLQESTRFSQLVEELLKII 90
             +L+ +   + +V  L +++
Sbjct: 93  PGNLRPNRHLANIVRRLREVV 113


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 22/67 (32%), Positives = 38/67 (56%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q+   C ICL+   +PV T C H FC+ C+ +   Q +GP  CP C+    +R+L+ + 
Sbjct: 10 LQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNR 69

Query: 78 RFSQLVE 84
            +++ E
Sbjct: 70 PLAKMAE 76


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 2/75 (2%)

Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
          +  M + + CPICL+   EPVS +C H FC+ C+ ++   K G S CP+C+     ++L+
Sbjct: 7  LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV--GKGGGSVCPVCRQRFLLKNLR 64

Query: 75 ESTRFSQLVEELLKI 89
           + + + +V  L +I
Sbjct: 65 PNRQLANMVNNLKEI 79


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo
          sapiens]
          Length = 488

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/67 (34%), Positives = 36/67 (53%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q    C +CLE +KEPV  +C H FCK C+ +     +    CP+C+     RSL+ + 
Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82

Query: 78 RFSQLVE 84
          +   +VE
Sbjct: 83 QLGSMVE 89


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo
          sapiens]
          Length = 518

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 23/67 (34%), Positives = 36/67 (53%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q    C +CLE +KEPV  +C H FCK C+ +     +    CP+C+     RSL+ + 
Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82

Query: 78 RFSQLVE 84
          +   +VE
Sbjct: 83 QLGSMVE 89


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 20/75 (26%), Positives = 42/75 (56%)

Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
          + ++++ + C ICL+ +++PV+  C H+FC+ C   +         CPLCK    K +++
Sbjct: 7  LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIR 66

Query: 75 ESTRFSQLVEELLKI 89
             + + LVE + ++
Sbjct: 67 PVWQLASLVENIERL 81


>gi|6005747 ring finger protein 2 [Homo sapiens]
          Length = 336

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)

Query: 22  LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
           L CPICL+++K  ++TK C H FC  C++  L  + G  +CP C K  ++KRSL+    F
Sbjct: 49  LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106

Query: 80  SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
             L+ ++      ++   +  L   N +N       +  H  +E   IQ+M   NR +R 
Sbjct: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159

Query: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
            + + EN S  ++   S   SN  T
Sbjct: 160 KKQQIENGSGAEDNGDSSHCSNAST 184


>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
           sapiens]
          Length = 773

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 23  ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
           EC +C+ L  EPV+T C H FCK C+ + L+       CPLCK  + +         +QL
Sbjct: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534

Query: 83  VEELL 87
           +EEL+
Sbjct: 535 LEELI 539



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)

Query: 21  ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
           +L C  C   + EPV+  C H +C+ C+ + L      ++C LC++
Sbjct: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo
          sapiens]
          Length = 488

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
          V+  +++ + CPICLEL+ EP+S  C H FC+ C+     + +  ++G   CP+C+    
Sbjct: 5  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64

Query: 70 KRSLQESTRFSQLVEELLKII 90
            +L+ +   + +V  L +++
Sbjct: 65 PGNLRPNRHLANIVRRLREVV 85


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 14  VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
           V+  +++ + CPICLEL+ EP+S  C H FC+ C+     + +  ++G   CP+C+    
Sbjct: 33  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 70  KRSLQESTRFSQLVEELLKII 90
             +L+ +   + +V  L +++
Sbjct: 93  PGNLRPNRHLANIVRRLREVV 113


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 6/78 (7%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ-----CPLCKNDI 68
          ++ A+ + + CPIC+  ++EP+S  C H FC  C L  L +  G SQ     CPLC+  +
Sbjct: 6  LVEAIVEEVACPICMTFLREPMSIDCGHSFCHSC-LSGLWEIPGESQNWGYTCPLCRAPV 64

Query: 69 TKRSLQESTRFSQLVEEL 86
            R+L+ + + + +VE++
Sbjct: 65 QPRNLRPNWQLANVVEKV 82


>gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]
          Length = 245

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 20/49 (40%), Positives = 34/49 (69%), Gaps = 3/49 (6%)

Query: 24 CPICLELIKEPV-STKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKR 71
          CP+C E++K PV +T C H+FC+ C L  +  ++  + CPLC+ ++T+R
Sbjct: 18 CPVCQEVLKTPVRTTACQHVFCRKCFLTAM--RESGAHCPLCRGNVTRR 64


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,657,442
Number of Sequences: 37866
Number of extensions: 1211780
Number of successful extensions: 4658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 203
Number of HSP's successfully gapped in prelim test: 269
Number of HSP's that attempted gapping in prelim test: 4179
Number of HSP's gapped (non-prelim): 675
length of query: 699
length of database: 18,247,518
effective HSP length: 109
effective length of query: 590
effective length of database: 14,120,124
effective search space: 8330873160
effective search space used: 8330873160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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