BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] (699 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 1406 0.0 gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 1341 0.0 gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 828 0.0 gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 828 0.0 gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 820 0.0 gi|62865604 tripartite motif protein 31 [Homo sapiens] 65 3e-10 gi|21071052 helicase-like transcription factor [Homo sapiens] 59 2e-08 gi|21071054 helicase-like transcription factor [Homo sapiens] 59 2e-08 gi|117938316 tripartite motif-containing 22 [Homo sapiens] 58 3e-08 gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 57 6e-08 gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 56 1e-07 gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 56 1e-07 gi|30023818 tripartite motif protein 50A [Homo sapiens] 56 1e-07 gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 54 4e-07 gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 54 4e-07 gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 54 4e-07 gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 54 4e-07 gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 54 4e-07 gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 54 4e-07 gi|21630277 tripartite motif-containing 11 [Homo sapiens] 54 5e-07 gi|15208660 tripartite motif protein 21 [Homo sapiens] 54 5e-07 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 54 5e-07 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 54 5e-07 gi|4508005 tripartite motif-containing 26 [Homo sapiens] 54 5e-07 gi|6005747 ring finger protein 2 [Homo sapiens] 54 6e-07 gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 54 6e-07 gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 53 1e-06 gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 53 1e-06 gi|37622899 ring finger protein 137 [Homo sapiens] 53 1e-06 gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens] 53 1e-06 >gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] Length = 699 Score = 1406 bits (3639), Expect = 0.0 Identities = 699/699 (100%), Positives = 699/699 (100%) Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300 Query: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360 Query: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS Sbjct: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420 Query: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA Sbjct: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480 Query: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE Sbjct: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540 Query: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF Sbjct: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600 Query: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL Sbjct: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660 Query: 661 EICCYGPFTNMPTGCPPNCGCAARCLDRGQWLPCNWADV 699 EICCYGPFTNMPTGCPPNCGCAARCLDRGQWLPCNWADV Sbjct: 661 EICCYGPFTNMPTGCPPNCGCAARCLDRGQWLPCNWADV 699 >gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] Length = 759 Score = 1341 bits (3470), Expect = 0.0 Identities = 673/673 (100%), Positives = 673/673 (100%) Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300 Query: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360 Query: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS Sbjct: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420 Query: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA Sbjct: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480 Query: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE Sbjct: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540 Query: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF Sbjct: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600 Query: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL Sbjct: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660 Query: 661 EICCYGPFTNMPT 673 EICCYGPFTNMPT Sbjct: 661 EICCYGPFTNMPT 673 >gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] Length = 1816 Score = 828 bits (2138), Expect = 0.0 Identities = 463/679 (68%), Positives = 508/679 (74%), Gaps = 20/679 (2%) Query: 6 LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65 ++ +E + V+ + + + +++P+ + C LL+ + + Sbjct: 1061 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1120 Query: 66 NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122 NDI + S FS+ V+ EL + F T A Y AKK +S E+L E Sbjct: 1121 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1173 Query: 123 SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182 + + K + + P + T + LS L K + V + Sbjct: 1174 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1231 Query: 183 GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238 S SE+T A+ S EL +T T+D + S+K+ + V ++ Sbjct: 1232 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1291 Query: 239 HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295 S+++ T E E+ + GEAASGCESETSVSEDCSGLSSQSDILTTQQRD Sbjct: 1292 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1351 Query: 296 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ Sbjct: 1352 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1411 Query: 355 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ Sbjct: 1412 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1471 Query: 415 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD Sbjct: 1472 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1531 Query: 475 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE Sbjct: 1532 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1591 Query: 535 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE Sbjct: 1592 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1651 Query: 595 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR Sbjct: 1652 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1711 Query: 655 KIFRGLEICCYGPFTNMPT 673 KIFRGLEICCYGPFTNMPT Sbjct: 1712 KIFRGLEICCYGPFTNMPT 1730 Score = 436 bits (1121), Expect = e-122 Identities = 288/538 (53%), Positives = 323/538 (60%), Gaps = 51/538 (9%) Query: 48 MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 107 MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF Sbjct: 1 MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 60 Query: 108 AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 167 AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT Sbjct: 61 AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 120 Query: 168 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 227 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE Sbjct: 121 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 180 Query: 228 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ- 285 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQG + S E + S L + Sbjct: 181 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHEN 240 Query: 286 SDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQS 345 S +L T+ R + E AE +Q G S + D R P S Sbjct: 241 SSLLLTKDR---------MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--S 288 Query: 346 TSEKVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWY 405 T +KV L+AD + +K K P E ++ D W Sbjct: 289 TEKKV----------------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWI 326 Query: 406 MHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGIS 465 + S N + +EL+ D + + E + D+ SG S Sbjct: 327 TLNSSIQKVNEWFSRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSS 379 Query: 466 LFSDDPESDPSEDRAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYN 522 D SDP E +S RV S K+ + A P +H T+ G Sbjct: 380 EKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAF 439 Query: 523 AMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580 E + +E+P LT KR SGL PE+F+ A + + N T +T Sbjct: 440 VTEPQIIQERP-LTNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 492 >gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] Length = 1863 Score = 828 bits (2138), Expect = 0.0 Identities = 463/679 (68%), Positives = 508/679 (74%), Gaps = 20/679 (2%) Query: 6 LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65 ++ +E + V+ + + + +++P+ + C LL+ + + Sbjct: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167 Query: 66 NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122 NDI + S FS+ V+ EL + F T A Y AKK +S E+L E Sbjct: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220 Query: 123 SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182 + + K + + P + T + LS L K + V + Sbjct: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278 Query: 183 GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238 S SE+T A+ S EL +T T+D + S+K+ + V ++ Sbjct: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338 Query: 239 HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295 S+++ T E E+ + GEAASGCESETSVSEDCSGLSSQSDILTTQQRD Sbjct: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398 Query: 296 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ Sbjct: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1458 Query: 355 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ Sbjct: 1459 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1518 Query: 415 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD Sbjct: 1519 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1578 Query: 475 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE Sbjct: 1579 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1638 Query: 535 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE Sbjct: 1639 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1698 Query: 595 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR Sbjct: 1699 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1758 Query: 655 KIFRGLEICCYGPFTNMPT 673 KIFRGLEICCYGPFTNMPT Sbjct: 1759 KIFRGLEICCYGPFTNMPT 1777 Score = 532 bits (1371), Expect = e-151 Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%) Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298 PSNNDLNTTEKRAAERHPEKYQG + S E + S L + S +L T+ R Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296 Query: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358 + E AE +Q G S + D R P ST +KV Sbjct: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340 Query: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418 L+AD + +K K P E ++ D W + S N + Sbjct: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386 Query: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478 +EL+ D + + E + D+ SG S D SDP E Sbjct: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439 Query: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535 +S RV S K+ + A P +H T+ G E + +E+P L Sbjct: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498 Query: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580 T KR SGL PE+F+ A + + N T +T Sbjct: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539 >gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] Length = 1884 Score = 820 bits (2117), Expect = 0.0 Identities = 463/700 (66%), Positives = 508/700 (72%), Gaps = 41/700 (5%) Query: 6 LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65 ++ +E + V+ + + + +++P+ + C LL+ + + Sbjct: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167 Query: 66 NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122 NDI + S FS+ V+ EL + F T A Y AKK +S E+L E Sbjct: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220 Query: 123 SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182 + + K + + P + T + LS L K + V + Sbjct: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278 Query: 183 GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238 S SE+T A+ S EL +T T+D + S+K+ + V ++ Sbjct: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338 Query: 239 HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295 S+++ T E E+ + GEAASGCESETSVSEDCSGLSSQSDILTTQQRD Sbjct: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398 Query: 296 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK------ 349 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK Sbjct: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKDSHIHG 1458 Query: 350 ----------------VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS 393 VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS Sbjct: 1459 QRNNSMFSKRPREHISVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS 1518 Query: 394 PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD 453 PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD Sbjct: 1519 PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD 1578 Query: 454 LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA 513 LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA Sbjct: 1579 LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA 1638 Query: 514 HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT 573 HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT Sbjct: 1639 HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT 1698 Query: 574 NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR 633 NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR Sbjct: 1699 NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR 1758 Query: 634 GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPT 673 GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPT Sbjct: 1759 GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPT 1798 Score = 532 bits (1371), Expect = e-151 Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%) Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60 Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120 Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180 Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240 Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298 PSNNDLNTTEKRAAERHPEKYQG + S E + S L + S +L T+ R Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296 Query: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358 + E AE +Q G S + D R P ST +KV Sbjct: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340 Query: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418 L+AD + +K K P E ++ D W + S N + Sbjct: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386 Query: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478 +EL+ D + + E + D+ SG S D SDP E Sbjct: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439 Query: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535 +S RV S K+ + A P +H T+ G E + +E+P L Sbjct: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498 Query: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580 T KR SGL PE+F+ A + + N T +T Sbjct: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539 >gi|62865604 tripartite motif protein 31 [Homo sapiens] Length = 425 Score = 64.7 bits (156), Expect = 3e-10 Identities = 33/103 (32%), Positives = 56/103 (54%), Gaps = 11/103 (10%) Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74 +N +Q+ + CPICL+++++PV+ C H FC C+ ++ G +CPLCK + K ++ Sbjct: 7 VNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSVRKNAI- 65 Query: 75 ESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEH 117 RF+ L+ L++ I A Q A+ +KE P H Sbjct: 66 ---RFNSLLRNLVEKIQALQ-------ASEVQSKRKEATCPRH 98 >gi|21071052 helicase-like transcription factor [Homo sapiens] Length = 1009 Score = 58.9 bits (141), Expect = 2e-08 Identities = 23/53 (43%), Positives = 37/53 (69%) Query: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75 EC ICL+ + PV T C H+FCK C+ +++ ++ ++CPLC+NDI + +L E Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811 >gi|21071054 helicase-like transcription factor [Homo sapiens] Length = 1009 Score = 58.9 bits (141), Expect = 2e-08 Identities = 23/53 (43%), Positives = 37/53 (69%) Query: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75 EC ICL+ + PV T C H+FCK C+ +++ ++ ++CPLC+NDI + +L E Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811 >gi|117938316 tripartite motif-containing 22 [Homo sapiens] Length = 498 Score = 57.8 bits (138), Expect = 3e-08 Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQ----KKGPSQCPLCKNDITKRSL 73 ++K + CPICLEL+ EP+S C H FC+ C+ + + +G S CP+C+ +L Sbjct: 9 IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68 Query: 74 QESTRFSQLVEELLKI 89 + + + +VE + ++ Sbjct: 69 RPNRHLANIVERVKEV 84 >gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo sapiens] Length = 493 Score = 57.0 bits (136), Expect = 6e-08 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70 ++N +++ CPICLEL+ +P+S C H FC+ C+ K KG S CP+C+ Sbjct: 6 LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64 Query: 71 RSLQESTRFSQLVEELLKI 89 +++ + + LVE+L ++ Sbjct: 65 ENIRPNRHVANLVEKLREV 83 >gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo sapiens] Length = 326 Score = 56.2 bits (134), Expect = 1e-07 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70 ++N +++ CPICLEL+ +P+S C H FC+ C+ K KG S CP+C+ Sbjct: 6 LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64 Query: 71 RSLQESTRFSQLVEELLKI 89 +++ + + +VE+L ++ Sbjct: 65 ENIRPNRHVANIVEKLREV 83 >gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo sapiens] Length = 347 Score = 56.2 bits (134), Expect = 1e-07 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70 ++N +++ CPICLEL+ +P+S C H FC+ C+ K KG S CP+C+ Sbjct: 6 LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64 Query: 71 RSLQESTRFSQLVEELLKI 89 +++ + + +VE+L ++ Sbjct: 65 ENIRPNRHVANIVEKLREV 83 >gi|30023818 tripartite motif protein 50A [Homo sapiens] Length = 487 Score = 56.2 bits (134), Expect = 1e-07 Identities = 22/65 (33%), Positives = 38/65 (58%) Query: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81 L+CPICLE+ KEP+ +C H +CK C++ L +CP+C+ + S + ++ Sbjct: 14 LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73 Query: 82 LVEEL 86 ++E L Sbjct: 74 VIEAL 78 >gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] Length = 270 Score = 54.3 bits (129), Expect = 4e-07 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73 +Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68 Query: 74 QESTRFSQLVEELLKI 89 Q + + +VE L ++ Sbjct: 69 QANQHLANIVERLKEV 84 >gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 54.3 bits (129), Expect = 4e-07 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73 +Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68 Query: 74 QESTRFSQLVEELLKI 89 Q + + +VE L ++ Sbjct: 69 QANQHLANIVERLKEV 84 >gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 54.3 bits (129), Expect = 4e-07 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73 +Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68 Query: 74 QESTRFSQLVEELLKI 89 Q + + +VE L ++ Sbjct: 69 QANQHLANIVERLKEV 84 >gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo sapiens] Length = 500 Score = 54.3 bits (129), Expect = 4e-07 Identities = 23/68 (33%), Positives = 40/68 (58%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77 +Q+ L CPICL+ ++PVS +C H FC+ C+ + GP CP C++ +L+ + Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65 Query: 78 RFSQLVEE 85 ++L E+ Sbjct: 66 ALARLTEK 73 >gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sapiens] Length = 474 Score = 54.3 bits (129), Expect = 4e-07 Identities = 23/68 (33%), Positives = 40/68 (58%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77 +Q+ L CPICL+ ++PVS +C H FC+ C+ + GP CP C++ +L+ + Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65 Query: 78 RFSQLVEE 85 ++L E+ Sbjct: 66 ALARLTEK 73 >gi|51477690 tripartite motif-containing 6 and tripartite motif-containing 34 [Homo sapiens] Length = 842 Score = 54.3 bits (129), Expect = 4e-07 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73 +Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L Sbjct: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422 Query: 74 QESTRFSQLVEELLKI 89 Q + + +VE L ++ Sbjct: 423 QANQHLANIVERLKEV 438 Score = 52.8 bits (125), Expect = 1e-06 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69 V+ +++ + CPICLEL+ EP+S C H FC+ C+ + + ++G CP+C+ Sbjct: 33 VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92 Query: 70 KRSLQESTRFSQLVEELLKII 90 +L+ + + +V L +++ Sbjct: 93 PGNLRPNRHLANIVRRLREVV 113 >gi|21630277 tripartite motif-containing 11 [Homo sapiens] Length = 468 Score = 53.9 bits (128), Expect = 5e-07 Identities = 22/67 (32%), Positives = 38/67 (56%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77 +Q+ C ICL+ +PV T C H FC+ C+ + Q +GP CP C+ +R+L+ + Sbjct: 10 LQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNR 69 Query: 78 RFSQLVE 84 +++ E Sbjct: 70 PLAKMAE 76 >gi|15208660 tripartite motif protein 21 [Homo sapiens] Length = 475 Score = 53.9 bits (128), Expect = 5e-07 Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 2/75 (2%) Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74 + M + + CPICL+ EPVS +C H FC+ C+ ++ K G S CP+C+ ++L+ Sbjct: 7 LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV--GKGGGSVCPVCRQRFLLKNLR 64 Query: 75 ESTRFSQLVEELLKI 89 + + + +V L +I Sbjct: 65 PNRQLANMVNNLKEI 79 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 53.9 bits (128), Expect = 5e-07 Identities = 23/67 (34%), Positives = 36/67 (53%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77 +Q C +CLE +KEPV +C H FCK C+ + + CP+C+ RSL+ + Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82 Query: 78 RFSQLVE 84 + +VE Sbjct: 83 QLGSMVE 89 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 53.9 bits (128), Expect = 5e-07 Identities = 23/67 (34%), Positives = 36/67 (53%) Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77 +Q C +CLE +KEPV +C H FCK C+ + + CP+C+ RSL+ + Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82 Query: 78 RFSQLVE 84 + +VE Sbjct: 83 QLGSMVE 89 >gi|4508005 tripartite motif-containing 26 [Homo sapiens] Length = 539 Score = 53.9 bits (128), Expect = 5e-07 Identities = 20/75 (26%), Positives = 42/75 (56%) Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74 + ++++ + C ICL+ +++PV+ C H+FC+ C + CPLCK K +++ Sbjct: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIR 66 Query: 75 ESTRFSQLVEELLKI 89 + + LVE + ++ Sbjct: 67 PVWQLASLVENIERL 81 >gi|6005747 ring finger protein 2 [Homo sapiens] Length = 336 Score = 53.5 bits (127), Expect = 6e-07 Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%) Query: 22 LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79 L CPICL+++K ++TK C H FC C++ L + G +CP C K ++KRSL+ F Sbjct: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106 Query: 80 SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137 L+ ++ ++ + L N +N + H +E IQ+M NR +R Sbjct: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159 Query: 138 LQSEPENPS-LQETSLSVQLSNLGT 161 + + EN S ++ S SN T Sbjct: 160 KKQQIENGSGAEDNGDSSHCSNAST 184 >gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo sapiens] Length = 773 Score = 53.5 bits (127), Expect = 6e-07 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Query: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82 EC +C+ L EPV+T C H FCK C+ + L+ CPLCK + + +QL Sbjct: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534 Query: 83 VEELL 87 +EEL+ Sbjct: 535 LEELI 539 Score = 34.3 bits (77), Expect = 0.40 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%) Query: 21 ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66 +L C C + EPV+ C H +C+ C+ + L ++C LC++ Sbjct: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160 >gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] Length = 488 Score = 52.8 bits (125), Expect = 1e-06 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69 V+ +++ + CPICLEL+ EP+S C H FC+ C+ + + ++G CP+C+ Sbjct: 5 VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64 Query: 70 KRSLQESTRFSQLVEELLKII 90 +L+ + + +V L +++ Sbjct: 65 PGNLRPNRHLANIVRRLREVV 85 >gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] Length = 516 Score = 52.8 bits (125), Expect = 1e-06 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69 V+ +++ + CPICLEL+ EP+S C H FC+ C+ + + ++G CP+C+ Sbjct: 33 VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92 Query: 70 KRSLQESTRFSQLVEELLKII 90 +L+ + + +V L +++ Sbjct: 93 PGNLRPNRHLANIVRRLREVV 113 >gi|37622899 ring finger protein 137 [Homo sapiens] Length = 485 Score = 52.8 bits (125), Expect = 1e-06 Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 6/78 (7%) Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ-----CPLCKNDI 68 ++ A+ + + CPIC+ ++EP+S C H FC C L L + G SQ CPLC+ + Sbjct: 6 LVEAIVEEVACPICMTFLREPMSIDCGHSFCHSC-LSGLWEIPGESQNWGYTCPLCRAPV 64 Query: 69 TKRSLQESTRFSQLVEEL 86 R+L+ + + + +VE++ Sbjct: 65 QPRNLRPNWQLANVVEKV 82 >gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens] Length = 245 Score = 52.8 bits (125), Expect = 1e-06 Identities = 20/49 (40%), Positives = 34/49 (69%), Gaps = 3/49 (6%) Query: 24 CPICLELIKEPV-STKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKR 71 CP+C E++K PV +T C H+FC+ C L + ++ + CPLC+ ++T+R Sbjct: 18 CPVCQEVLKTPVRTTACQHVFCRKCFLTAM--RESGAHCPLCRGNVTRR 64 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.362 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,657,442 Number of Sequences: 37866 Number of extensions: 1211780 Number of successful extensions: 4658 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 203 Number of HSP's successfully gapped in prelim test: 269 Number of HSP's that attempted gapping in prelim test: 4179 Number of HSP's gapped (non-prelim): 675 length of query: 699 length of database: 18,247,518 effective HSP length: 109 effective length of query: 590 effective length of database: 14,120,124 effective search space: 8330873160 effective search space used: 8330873160 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.