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Search of human proteins with 237681123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237681123 breast cancer 1, early onset isoform 4 [Homo
sapiens]
(759 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 1521 0.0
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 1341 0.0
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 1008 0.0
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 1008 0.0
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 1000 0.0
gi|62865604 tripartite motif protein 31 [Homo sapiens] 65 3e-10
gi|21071052 helicase-like transcription factor [Homo sapiens] 59 2e-08
gi|21071054 helicase-like transcription factor [Homo sapiens] 59 2e-08
gi|117938316 tripartite motif-containing 22 [Homo sapiens] 58 4e-08
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 57 6e-08
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 56 1e-07
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 56 1e-07
gi|30023818 tripartite motif protein 50A [Homo sapiens] 56 1e-07
gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens] 55 3e-07
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 54 4e-07
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 54 4e-07
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 54 4e-07
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 54 4e-07
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 54 4e-07
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 54 4e-07
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 54 5e-07
gi|15208660 tripartite motif protein 21 [Homo sapiens] 54 5e-07
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 54 5e-07
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 54 5e-07
gi|4508005 tripartite motif-containing 26 [Homo sapiens] 54 5e-07
gi|6005747 ring finger protein 2 [Homo sapiens] 54 7e-07
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 54 7e-07
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 53 1e-06
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 53 1e-06
gi|37622899 ring finger protein 137 [Homo sapiens] 53 1e-06
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 1521 bits (3938), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300
PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300
Query: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360
LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP
Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360
Query: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420
ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS
Sbjct: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420
Query: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480
QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA
Sbjct: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480
Query: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540
PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE
Sbjct: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540
Query: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600
RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF
Sbjct: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600
Query: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660
LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL
Sbjct: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660
Query: 661 EICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAI 720
EICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAI
Sbjct: 661 EICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAI 720
Query: 721 GQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 759
GQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
Sbjct: 721 GQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 759
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 1341 bits (3470), Expect = 0.0
Identities = 673/673 (100%), Positives = 673/673 (100%)
Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300
PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHN 300
Query: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360
LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP
Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSEYP 360
Query: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420
ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS
Sbjct: 361 ISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPS 420
Query: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480
QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA
Sbjct: 421 QEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRA 480
Query: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540
PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE
Sbjct: 481 PESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 540
Query: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600
RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF
Sbjct: 541 RVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYF 600
Query: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660
LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL
Sbjct: 601 LGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGL 660
Query: 661 EICCYGPFTNMPT 673
EICCYGPFTNMPT
Sbjct: 661 EICCYGPFTNMPT 673
>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
Length = 1816
Score = 1008 bits (2606), Expect = 0.0
Identities = 549/765 (71%), Positives = 594/765 (77%), Gaps = 20/765 (2%)
Query: 6 LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65
++ +E + V+ + + + +++P+ + C LL+ + +
Sbjct: 1061 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1120
Query: 66 NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122
NDI + S FS+ V+ EL + F T A Y AKK +S E+L E
Sbjct: 1121 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1173
Query: 123 SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182
+ + K + + P + T + LS L K + V +
Sbjct: 1174 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1231
Query: 183 GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238
S SE+T A+ S EL +T T+D + S+K+ + V ++
Sbjct: 1232 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1291
Query: 239 HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295
S+++ T E E+ + GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 1292 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1351
Query: 296 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354
TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ
Sbjct: 1352 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1411
Query: 355 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414
KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ
Sbjct: 1412 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1471
Query: 415 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474
NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD
Sbjct: 1472 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1531
Query: 475 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534
PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE
Sbjct: 1532 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1591
Query: 535 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594
LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE
Sbjct: 1592 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1651
Query: 595 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654
RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR
Sbjct: 1652 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1711
Query: 655 KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED 714
KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED
Sbjct: 1712 KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED 1771
Query: 715 NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 759
NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
Sbjct: 1772 NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 1816
Score = 436 bits (1121), Expect = e-122
Identities = 288/538 (53%), Positives = 323/538 (60%), Gaps = 51/538 (9%)
Query: 48 MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 107
MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF
Sbjct: 1 MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 60
Query: 108 AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 167
AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT
Sbjct: 61 AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 120
Query: 168 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 227
KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE
Sbjct: 121 KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 180
Query: 228 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ- 285
FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQG + S E + S L +
Sbjct: 181 FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHEN 240
Query: 286 SDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQS 345
S +L T+ R + E AE +Q G S + D R P S
Sbjct: 241 SSLLLTKDR---------MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--S 288
Query: 346 TSEKVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWY 405
T +KV L+AD + +K K P E ++ D W
Sbjct: 289 TEKKV----------------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWI 326
Query: 406 MHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGIS 465
+ S N + +EL+ D + + E + D+ SG S
Sbjct: 327 TLNSSIQKVNEWFSRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSS 379
Query: 466 LFSDDPESDPSEDRAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYN 522
D SDP E +S RV S K+ + A P +H T+ G
Sbjct: 380 EKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAF 439
Query: 523 AMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580
E + +E+P LT KR SGL PE+F+ A + + N T +T
Sbjct: 440 VTEPQIIQERP-LTNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 492
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 1008 bits (2606), Expect = 0.0
Identities = 549/765 (71%), Positives = 594/765 (77%), Gaps = 20/765 (2%)
Query: 6 LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65
++ +E + V+ + + + +++P+ + C LL+ + +
Sbjct: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167
Query: 66 NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122
NDI + S FS+ V+ EL + F T A Y AKK +S E+L E
Sbjct: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220
Query: 123 SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182
+ + K + + P + T + LS L K + V +
Sbjct: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278
Query: 183 GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238
S SE+T A+ S EL +T T+D + S+K+ + V ++
Sbjct: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338
Query: 239 HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295
S+++ T E E+ + GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398
Query: 296 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354
TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ
Sbjct: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1458
Query: 355 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414
KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ
Sbjct: 1459 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1518
Query: 415 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474
NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD
Sbjct: 1519 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1578
Query: 475 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534
PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE
Sbjct: 1579 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1638
Query: 535 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594
LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE
Sbjct: 1639 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1698
Query: 595 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654
RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR
Sbjct: 1699 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1758
Query: 655 KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED 714
KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED
Sbjct: 1759 KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED 1818
Query: 715 NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 759
NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
Sbjct: 1819 NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 1863
Score = 532 bits (1371), Expect = e-151
Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%)
Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298
PSNNDLNTTEKRAAERHPEKYQG + S E + S L + S +L T+ R
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296
Query: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358
+ E AE +Q G S + D R P ST +KV
Sbjct: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340
Query: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418
L+AD + +K K P E ++ D W + S N +
Sbjct: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386
Query: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478
+EL+ D + + E + D+ SG S D SDP E
Sbjct: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439
Query: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535
+S RV S K+ + A P +H T+ G E + +E+P L
Sbjct: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498
Query: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580
T KR SGL PE+F+ A + + N T +T
Sbjct: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 1000 bits (2585), Expect = 0.0
Identities = 549/786 (69%), Positives = 594/786 (75%), Gaps = 41/786 (5%)
Query: 6 LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65
++ +E + V+ + + + +++P+ + C LL+ + +
Sbjct: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167
Query: 66 NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122
NDI + S FS+ V+ EL + F T A Y AKK +S E+L E
Sbjct: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220
Query: 123 SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182
+ + K + + P + T + LS L K + V +
Sbjct: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278
Query: 183 GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238
S SE+T A+ S EL +T T+D + S+K+ + V ++
Sbjct: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338
Query: 239 HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295
S+++ T E E+ + GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398
Query: 296 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK------ 349
TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK
Sbjct: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKDSHIHG 1458
Query: 350 ----------------VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS 393
VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS
Sbjct: 1459 QRNNSMFSKRPREHISVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSS 1518
Query: 394 PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD 453
PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD
Sbjct: 1519 PSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQD 1578
Query: 454 LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA 513
LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA
Sbjct: 1579 LEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAA 1638
Query: 514 HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT 573
HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT
Sbjct: 1639 HTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLT 1698
Query: 574 NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR 633
NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR
Sbjct: 1699 NLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVR 1758
Query: 634 GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSS 693
GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSS
Sbjct: 1759 GDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSS 1818
Query: 694 FTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQ 753
FTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQ
Sbjct: 1819 FTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQ 1878
Query: 754 IPHSHY 759
IPHSHY
Sbjct: 1879 IPHSHY 1884
Score = 532 bits (1371), Expect = e-151
Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%)
Query: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
Query: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
Query: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298
PSNNDLNTTEKRAAERHPEKYQG + S E + S L + S +L T+ R
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296
Query: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358
+ E AE +Q G S + D R P ST +KV
Sbjct: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340
Query: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418
L+AD + +K K P E ++ D W + S N +
Sbjct: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386
Query: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478
+EL+ D + + E + D+ SG S D SDP E
Sbjct: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439
Query: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535
+S RV S K+ + A P +H T+ G E + +E+P L
Sbjct: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498
Query: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580
T KR SGL PE+F+ A + + N T +T
Sbjct: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 64.7 bits (156), Expect = 3e-10
Identities = 33/103 (32%), Positives = 56/103 (54%), Gaps = 11/103 (10%)
Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
+N +Q+ + CPICL+++++PV+ C H FC C+ ++ G +CPLCK + K ++
Sbjct: 7 VNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSVRKNAI- 65
Query: 75 ESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEH 117
RF+ L+ L++ I A Q A+ +KE P H
Sbjct: 66 ---RFNSLLRNLVEKIQALQ-------ASEVQSKRKEATCPRH 98
>gi|21071052 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 58.9 bits (141), Expect = 2e-08
Identities = 23/53 (43%), Positives = 37/53 (69%)
Query: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75
EC ICL+ + PV T C H+FCK C+ +++ ++ ++CPLC+NDI + +L E
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811
>gi|21071054 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 58.9 bits (141), Expect = 2e-08
Identities = 23/53 (43%), Positives = 37/53 (69%)
Query: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75
EC ICL+ + PV T C H+FCK C+ +++ ++ ++CPLC+NDI + +L E
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811
>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
Length = 498
Score = 57.8 bits (138), Expect = 4e-08
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQ----KKGPSQCPLCKNDITKRSL 73
++K + CPICLEL+ EP+S C H FC+ C+ + + +G S CP+C+ +L
Sbjct: 9 IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68
Query: 74 QESTRFSQLVEELLKI 89
+ + + +VE + ++
Sbjct: 69 RPNRHLANIVERVKEV 84
>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
Length = 493
Score = 57.0 bits (136), Expect = 6e-08
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
++N +++ CPICLEL+ +P+S C H FC+ C+ K KG S CP+C+
Sbjct: 6 LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64
Query: 71 RSLQESTRFSQLVEELLKI 89
+++ + + LVE+L ++
Sbjct: 65 ENIRPNRHVANLVEKLREV 83
>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
sapiens]
Length = 326
Score = 56.2 bits (134), Expect = 1e-07
Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
++N +++ CPICLEL+ +P+S C H FC+ C+ K KG S CP+C+
Sbjct: 6 LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64
Query: 71 RSLQESTRFSQLVEELLKI 89
+++ + + +VE+L ++
Sbjct: 65 ENIRPNRHVANIVEKLREV 83
>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
sapiens]
Length = 347
Score = 56.2 bits (134), Expect = 1e-07
Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
++N +++ CPICLEL+ +P+S C H FC+ C+ K KG S CP+C+
Sbjct: 6 LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64
Query: 71 RSLQESTRFSQLVEELLKI 89
+++ + + +VE+L ++
Sbjct: 65 ENIRPNRHVANIVEKLREV 83
>gi|30023818 tripartite motif protein 50A [Homo sapiens]
Length = 487
Score = 56.2 bits (134), Expect = 1e-07
Identities = 22/65 (33%), Positives = 38/65 (58%)
Query: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
L+CPICLE+ KEP+ +C H +CK C++ L +CP+C+ + S + ++
Sbjct: 14 LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73
Query: 82 LVEEL 86
++E L
Sbjct: 74 VIEAL 78
>gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]
Length = 777
Score = 54.7 bits (130), Expect = 3e-07
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 526 ESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVM 585
ES S + + +R + + ++ SGL+ E+ ++ + A THVV+
Sbjct: 550 ESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVV 609
Query: 586 KTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGP 645
DA + TLK LGI G W++ + WV ++ + E +E+ +GP
Sbjct: 610 PGDA---VQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEI---------PEGP 657
Query: 646 KRARESQDR---KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVV 688
+R+R ++++ K+F G +G F + P D L +V G ++
Sbjct: 658 RRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQIL 703
Score = 39.7 bits (91), Expect = 0.011
Identities = 18/76 (23%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 15 INAMQKILECPICLELIKEPVST-KCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSL 73
++ ++K+L C C +++EPV C+HIFC C+ + + CP+C + L
Sbjct: 41 LDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIG-----TGCPVCYTPAWIQDL 95
Query: 74 QESTRFSQLVEELLKI 89
+ + + +++ K+
Sbjct: 96 KINRQLDSMIQLCSKL 111
>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
Length = 270
Score = 54.3 bits (129), Expect = 4e-07
Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
+Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L
Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68
Query: 74 QESTRFSQLVEELLKI 89
Q + + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 54.3 bits (129), Expect = 4e-07
Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
+Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L
Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68
Query: 74 QESTRFSQLVEELLKI 89
Q + + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84
>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 54.3 bits (129), Expect = 4e-07
Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
+Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L
Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68
Query: 74 QESTRFSQLVEELLKI 89
Q + + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 54.3 bits (129), Expect = 4e-07
Identities = 23/68 (33%), Positives = 40/68 (58%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
+Q+ L CPICL+ ++PVS +C H FC+ C+ + GP CP C++ +L+ +
Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65
Query: 78 RFSQLVEE 85
++L E+
Sbjct: 66 ALARLTEK 73
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 54.3 bits (129), Expect = 4e-07
Identities = 23/68 (33%), Positives = 40/68 (58%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
+Q+ L CPICL+ ++PVS +C H FC+ C+ + GP CP C++ +L+ +
Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65
Query: 78 RFSQLVEE 85
++L E+
Sbjct: 66 ALARLTEK 73
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 54.3 bits (129), Expect = 4e-07
Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
+Q+ + CPICLEL+ EP+S C H C+ C+ + + G S CP+C + L
Sbjct: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422
Query: 74 QESTRFSQLVEELLKI 89
Q + + +VE L ++
Sbjct: 423 QANQHLANIVERLKEV 438
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
V+ +++ + CPICLEL+ EP+S C H FC+ C+ + + ++G CP+C+
Sbjct: 33 VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92
Query: 70 KRSLQESTRFSQLVEELLKII 90
+L+ + + +V L +++
Sbjct: 93 PGNLRPNRHLANIVRRLREVV 113
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 53.9 bits (128), Expect = 5e-07
Identities = 22/67 (32%), Positives = 38/67 (56%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
+Q+ C ICL+ +PV T C H FC+ C+ + Q +GP CP C+ +R+L+ +
Sbjct: 10 LQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNR 69
Query: 78 RFSQLVE 84
+++ E
Sbjct: 70 PLAKMAE 76
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
+ M + + CPICL+ EPVS +C H FC+ C+ ++ K G S CP+C+ ++L+
Sbjct: 7 LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV--GKGGGSVCPVCRQRFLLKNLR 64
Query: 75 ESTRFSQLVEELLKI 89
+ + + +V L +I
Sbjct: 65 PNRQLANMVNNLKEI 79
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo
sapiens]
Length = 488
Score = 53.9 bits (128), Expect = 5e-07
Identities = 23/67 (34%), Positives = 36/67 (53%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
+Q C +CLE +KEPV +C H FCK C+ + + CP+C+ RSL+ +
Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82
Query: 78 RFSQLVE 84
+ +VE
Sbjct: 83 QLGSMVE 89
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo
sapiens]
Length = 518
Score = 53.9 bits (128), Expect = 5e-07
Identities = 23/67 (34%), Positives = 36/67 (53%)
Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
+Q C +CLE +KEPV +C H FCK C+ + + CP+C+ RSL+ +
Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82
Query: 78 RFSQLVE 84
+ +VE
Sbjct: 83 QLGSMVE 89
>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
Length = 539
Score = 53.9 bits (128), Expect = 5e-07
Identities = 20/75 (26%), Positives = 42/75 (56%)
Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
+ ++++ + C ICL+ +++PV+ C H+FC+ C + CPLCK K +++
Sbjct: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIR 66
Query: 75 ESTRFSQLVEELLKI 89
+ + LVE + ++
Sbjct: 67 PVWQLASLVENIERL 81
>gi|6005747 ring finger protein 2 [Homo sapiens]
Length = 336
Score = 53.5 bits (127), Expect = 7e-07
Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 22 LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
L CPICL+++K ++TK C H FC C++ L + G +CP C K ++KRSL+ F
Sbjct: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106
Query: 80 SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
L+ ++ ++ + L N +N + H +E IQ+M NR +R
Sbjct: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159
Query: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
+ + EN S ++ S SN T
Sbjct: 160 KKQQIENGSGAEDNGDSSHCSNAST 184
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
EC +C+ L EPV+T C H FCK C+ + L+ CPLCK + + +QL
Sbjct: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534
Query: 83 VEELL 87
+EEL+
Sbjct: 535 LEELI 539
Score = 34.3 bits (77), Expect = 0.44
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 21 ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
+L C C + EPV+ C H +C+ C+ + L ++C LC++
Sbjct: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo
sapiens]
Length = 488
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
V+ +++ + CPICLEL+ EP+S C H FC+ C+ + + ++G CP+C+
Sbjct: 5 VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64
Query: 70 KRSLQESTRFSQLVEELLKII 90
+L+ + + +V L +++
Sbjct: 65 PGNLRPNRHLANIVRRLREVV 85
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
V+ +++ + CPICLEL+ EP+S C H FC+ C+ + + ++G CP+C+
Sbjct: 33 VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92
Query: 70 KRSLQESTRFSQLVEELLKII 90
+L+ + + +V L +++
Sbjct: 93 PGNLRPNRHLANIVRRLREVV 113
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 52.8 bits (125), Expect = 1e-06
Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 6/78 (7%)
Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ-----CPLCKNDI 68
++ A+ + + CPIC+ ++EP+S C H FC C L L + G SQ CPLC+ +
Sbjct: 6 LVEAIVEEVACPICMTFLREPMSIDCGHSFCHSC-LSGLWEIPGESQNWGYTCPLCRAPV 64
Query: 69 TKRSLQESTRFSQLVEEL 86
R+L+ + + + +VE++
Sbjct: 65 QPRNLRPNWQLANVVEKV 82
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,692,362
Number of Sequences: 37866
Number of extensions: 1298636
Number of successful extensions: 4685
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 199
Number of HSP's successfully gapped in prelim test: 246
Number of HSP's that attempted gapping in prelim test: 4235
Number of HSP's gapped (non-prelim): 621
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.