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Search of human proteins with 115583685
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
(500 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 1013 0.0
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 574 e-164
gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 380 e-105
gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 380 e-105
gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 380 e-105
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 363 e-100
gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 244 2e-64
gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 228 7e-60
gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 216 4e-56
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 205 7e-53
gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 191 1e-48
gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 190 2e-48
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 176 3e-44
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 164 2e-40
gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 158 1e-38
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 154 2e-37
gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 150 2e-36
gi|215272392 solute carrier family 18 (vesicular monoamine), mem... 40 0.005
gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 40 0.005
gi|208879454 solute carrier family 18 (vesicular monoamine), mem... 40 0.005
gi|4506987 solute carrier family 18 (vesicular monoamine), membe... 40 0.005
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 35 0.12
gi|42476325 solute carrier family 18 (vesicular monoamine), memb... 33 0.60
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 32 1.3
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 32 1.3
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 32 1.8
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 31 2.3
gi|31543630 solute carrier family 20 (phosphate transporter), me... 31 2.3
gi|223029432 solute carrier family 2 (facilitated glucose transp... 31 3.0
gi|223029430 solute carrier family 2 (facilitated glucose transp... 31 3.0
>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
Length = 500
Score = 1013 bits (2618), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW 60
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
Sbjct: 1 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW 60
Query: 61 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG 120
ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
Sbjct: 61 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG 120
Query: 121 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI 180
GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
Sbjct: 121 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI 180
Query: 181 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ 240
LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
Sbjct: 181 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ 240
Query: 241 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF 300
EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
Sbjct: 241 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF 300
Query: 301 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA 360
LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
Sbjct: 301 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA 360
Query: 361 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK 420
GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
Sbjct: 361 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK 420
Query: 421 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA 480
YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
Sbjct: 421 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA 480
Query: 481 AESPDQKDTDGGPKEEESPV 500
AESPDQKDTDGGPKEEESPV
Sbjct: 481 AESPDQKDTDGGPKEEESPV 500
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 574 bits (1479), Expect = e-164
Identities = 285/465 (61%), Positives = 355/465 (76%), Gaps = 16/465 (3%)
Query: 1 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW 60
MPP P + PPDGGWGW VV AFISIGFSYAFPK++TVFFKEI+ IFH T SE++W
Sbjct: 1 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW 60
Query: 61 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG 120
ISSIMLAVMY GGP+SS+LVNKYGSR V+I GG L G++ ASF ++V QLY+ +G I
Sbjct: 61 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT 120
Query: 121 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI 180
GLGLAFNL PALT+IGKYFY++RP+ANGLAMAGSPVFL +LAP NQ F FGW+GSFLI
Sbjct: 121 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI 180
Query: 181 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ 240
LG LLLN CVAG+LMRP+GP T + KSK K+G +D D++ I +
Sbjct: 181 LGSLLLNACVAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----K 224
Query: 241 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF 300
K+S ++ +N++LD +LF HRGFL+YLSGNVIMF G FAP++FL+ Y K Q +AF
Sbjct: 225 TKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF 284
Query: 301 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA 360
LLS++AFVDM ARPS+GL+AN+K IRPRIQYFF+ +++ NGVCH+L PL+ Y +YA
Sbjct: 285 LLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYA 344
Query: 361 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK 420
FFG FG +SSVLFETLMDLVG RFSSAVGLVTIVEC PVLLGPPL G+L D+ G+YK
Sbjct: 345 VFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYK 404
Query: 421 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEE 465
Y Y +CG +++ + ++L IG INYRLLAKE+K +++++E E
Sbjct: 405 YMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESE 449
>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 380 bits (976), Expect = e-105
Identities = 201/459 (43%), Positives = 274/459 (59%), Gaps = 40/459 (8%)
Query: 7 GPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIML 66
GP G PDGGWGWAV+ G F+ GFSYAFPK+++VFFKE+ F S+ +WISSI+L
Sbjct: 9 GPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILL 68
Query: 67 AVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAF 126
A++YG GP+ S+ VN++G R VM+VGG + G++AASFC ++ Q+Y+ GVI GLGLA
Sbjct: 69 AMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLAL 128
Query: 127 NLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLL 186
N P+L M+ +YF KRRP+ANGLA AGSPVFLC L+PL Q+ +GWRG FLILGGLLL
Sbjct: 129 NFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLL 188
Query: 187 NCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVF 246
NCCV ALMRP+ T G P + R
Sbjct: 189 NCCVCAALMRPL------------------------------VVTAQPGSGPPRPSR--- 215
Query: 247 QTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILA 306
+ LDL++F RGF+LY +M GLF P VF+ SY K K+AFLL+IL
Sbjct: 216 ----RLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILG 271
Query: 307 FVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFA 366
F+D+ ARP+ G VA +RP Y F+ S+ NG+ + + Y G V+ FFG +
Sbjct: 272 FIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGIS 331
Query: 367 FGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWAC 426
+G + ++ FE LM +VG +FSSA+GLV ++E VL+GPP G+L D Y Y +
Sbjct: 332 YGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILA 391
Query: 427 GVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEE 465
G ++ S + L +G N+ + K+ K + + + EEE
Sbjct: 392 GAEVLTSSLILLLG---NFFCIRKKPKEPQPEVAAAEEE 427
>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 380 bits (976), Expect = e-105
Identities = 201/459 (43%), Positives = 274/459 (59%), Gaps = 40/459 (8%)
Query: 7 GPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIML 66
GP G PDGGWGWAV+ G F+ GFSYAFPK+++VFFKE+ F S+ +WISSI+L
Sbjct: 9 GPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILL 68
Query: 67 AVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAF 126
A++YG GP+ S+ VN++G R VM+VGG + G++AASFC ++ Q+Y+ GVI GLGLA
Sbjct: 69 AMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLAL 128
Query: 127 NLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLL 186
N P+L M+ +YF KRRP+ANGLA AGSPVFLC L+PL Q+ +GWRG FLILGGLLL
Sbjct: 129 NFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLL 188
Query: 187 NCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVF 246
NCCV ALMRP+ T G P + R
Sbjct: 189 NCCVCAALMRPL------------------------------VVTAQPGSGPPRPSR--- 215
Query: 247 QTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILA 306
+ LDL++F RGF+LY +M GLF P VF+ SY K K+AFLL+IL
Sbjct: 216 ----RLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILG 271
Query: 307 FVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFA 366
F+D+ ARP+ G VA +RP Y F+ S+ NG+ + + Y G V+ FFG +
Sbjct: 272 FIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGIS 331
Query: 367 FGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWAC 426
+G + ++ FE LM +VG +FSSA+GLV ++E VL+GPP G+L D Y Y +
Sbjct: 332 YGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILA 391
Query: 427 GVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEE 465
G ++ S + L +G N+ + K+ K + + + EEE
Sbjct: 392 GAEVLTSSLILLLG---NFFCIRKKPKEPQPEVAAAEEE 427
>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 380 bits (976), Expect = e-105
Identities = 201/459 (43%), Positives = 274/459 (59%), Gaps = 40/459 (8%)
Query: 7 GPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIML 66
GP G PDGGWGWAV+ G F+ GFSYAFPK+++VFFKE+ F S+ +WISSI+L
Sbjct: 9 GPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILL 68
Query: 67 AVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAF 126
A++YG GP+ S+ VN++G R VM+VGG + G++AASFC ++ Q+Y+ GVI GLGLA
Sbjct: 69 AMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLAL 128
Query: 127 NLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLL 186
N P+L M+ +YF KRRP+ANGLA AGSPVFLC L+PL Q+ +GWRG FLILGGLLL
Sbjct: 129 NFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLL 188
Query: 187 NCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVF 246
NCCV ALMRP+ T G P + R
Sbjct: 189 NCCVCAALMRPL------------------------------VVTAQPGSGPPRPSR--- 215
Query: 247 QTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILA 306
+ LDL++F RGF+LY +M GLF P VF+ SY K K+AFLL+IL
Sbjct: 216 ----RLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILG 271
Query: 307 FVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFA 366
F+D+ ARP+ G VA +RP Y F+ S+ NG+ + + Y G V+ FFG +
Sbjct: 272 FIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGIS 331
Query: 367 FGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWAC 426
+G + ++ FE LM +VG +FSSA+GLV ++E VL+GPP G+L D Y Y +
Sbjct: 332 YGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILA 391
Query: 427 GVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEE 465
G ++ S + L +G N+ + K+ K + + + EEE
Sbjct: 392 GAEVLTSSLILLLG---NFFCIRKKPKEPQPEVAAAEEE 427
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 363 bits (933), Expect = e-100
Identities = 194/481 (40%), Positives = 282/481 (58%), Gaps = 13/481 (2%)
Query: 6 GGPV-GYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSI 64
GGP G PPDGGWGW V+ F+ GF+Y FPK+++VFF+ + F A S+ +W+SSI
Sbjct: 4 GGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSI 63
Query: 65 MLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGL 124
MLA++YG GP+SSILV ++G R VM+ GG L+ G+I ASF + +LY+ GV+ GLGL
Sbjct: 64 MLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGL 123
Query: 125 AFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGL 184
A N P+L M+G YF +RRPLANGLA AGSPVFL L+PL Q FGWRG FL+LGGL
Sbjct: 124 ALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGL 183
Query: 185 LLNCCVAGALMR-PIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKR 243
LL+CC GA+MR P GP P + + ++ ++AG + + + A L P+ R
Sbjct: 184 LLHCCACGAVMRPPPGPGP----RPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPR 239
Query: 244 SVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLS 303
+ LDL + T R F +Y +M GLF P + L +Y K +AFLLS
Sbjct: 240 ------RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLS 293
Query: 304 ILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFF 363
I+ FVD+VARP+ G +A +RP + Y F+ +++ANG+ + + + +Y + F
Sbjct: 294 IVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAF 353
Query: 364 GFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTY 423
G ++G + ++ FE LM VG RF SA+GLV +VE VL+GPP GRL D+ +Y+ +
Sbjct: 354 GLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIF 413
Query: 424 WACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAES 483
+ G + ++G+++ + R AK + + + + G + AE
Sbjct: 414 YLAGSEVALAGVFMAVATNCCLR-CAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEE 472
Query: 484 P 484
P
Sbjct: 473 P 473
>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
Length = 505
Score = 244 bits (622), Expect = 2e-64
Identities = 140/466 (30%), Positives = 240/466 (51%), Gaps = 30/466 (6%)
Query: 15 DGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGP 74
DG W W V++ ++ G + FP I +FF E++ F A+ SE SW SI+ AV++ GP
Sbjct: 9 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGP 68
Query: 75 ISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTM 134
+ SILV ++G R+ +++GG L+ G++A+SF + + QLY G I GLG+ F+ ++T+
Sbjct: 69 LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITV 128
Query: 135 IGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGAL 194
+G YF +RR LAN LA G + + L++ GWRG+FL+ GG+ L+CC+ GA+
Sbjct: 129 LGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAI 188
Query: 195 MRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLD 254
+RP+ K+ E T +G + +TI + L
Sbjct: 189 IRPVATSVAPETKECPPPPPE---------------TPALGC-----LAACGRTIQRHLA 228
Query: 255 LTLFTHR-GFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVAR 313
+ H G+ +Y+ G + G P VFL Y +++A L+SI+ F ++ R
Sbjct: 229 FDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLR 288
Query: 314 PSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTY---VGFCVYAGFFGFAFGWL 370
P GL+A +Y F+ +++ NG+ +++ S + VG+C+ + + +
Sbjct: 289 PLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCL---AYSVSMSGI 345
Query: 371 SSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVL 430
+++F+ LMD+V +F A+GL T+++ L+ PPL G L D ++ Y ++ L
Sbjct: 346 GALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFL 405
Query: 431 IISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNE 476
I + LF+G G Y L KEQ ++ E + ++ P +
Sbjct: 406 ISAA--LFMG-GSFYALQKKEQGKQAVAADALERDLFLEAKDGPGK 448
>gi|157041233 solute carrier family 16 (monocarboxylic acid
transporters), member 12 [Homo sapiens]
Length = 486
Score = 228 bits (582), Expect = 7e-60
Identities = 140/476 (29%), Positives = 241/476 (50%), Gaps = 15/476 (3%)
Query: 12 TPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYG 71
+PPDGGWGW +V G F+ + A + I++FF E + F ++ +WI SI+ V
Sbjct: 11 SPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTML 70
Query: 72 GGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPA 131
P+ S++ N ++ +++GG L+ GLI +SF +++ LY+ +GV+ GLG A +PA
Sbjct: 71 CAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPA 130
Query: 132 LTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191
+ M+GKYF +R+ LA G+AM+GS + LAP+ Q+ F WRG+ LILGG +LN CV
Sbjct: 131 IAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVC 190
Query: 192 GALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQ 251
GALMRPI K +++ + K +K+ + L + Q
Sbjct: 191 GALMRPITLKEDHTTPEQNHVC--RTQKEDIKR--VSPYSSLTKEWAQTCLCCCLQQEYS 246
Query: 252 FLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMV 311
FL ++ F++ + M +G V+L Y S S +++AFL+SIL +D++
Sbjct: 247 FLLMS-----DFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDII 301
Query: 312 ARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLS 371
+ G + + + ++ + +V +G+C++ P+ + ++ FG+ G
Sbjct: 302 GNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYV 361
Query: 372 SVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLI 431
+++ ++VG SSA+G+V + P L+ PP+ GRL D G Y + CG +I
Sbjct: 362 TLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMI 421
Query: 432 ISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQK 487
S + L + L K + + + +KE + + + + A DQK
Sbjct: 422 FSSVLL------GFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQK 471
>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
Length = 523
Score = 216 bits (550), Expect = 4e-56
Identities = 138/453 (30%), Positives = 216/453 (47%), Gaps = 32/453 (7%)
Query: 14 PDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGG 73
PDGGWGWAV + F F+Y K+ VFF ++ F+ + S +SWI SI + V+
Sbjct: 19 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSA 78
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P++++L N++G R+V+++GG L G++AASF V +YV IG+I GLG F+ P +T
Sbjct: 79 PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138
Query: 134 MIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGA 193
++ +YF KRR + +A G + AP GWR S L +G L LN + GA
Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198
Query: 194 LMRPI---GPKPTK-------------AGKDKSKASLEKAGKSGVKKDLHDANTDL---I 234
L+RPI GP K +K++ S++ SGV+ N +
Sbjct: 199 LLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSI-DSGVELTTSPKNVPTHTNL 257
Query: 235 GRHPKQEKRSVFQTIN--------QFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSS 286
PK + + V + LD ++ + F+ Y + G FAP +++
Sbjct: 258 ELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIP 317
Query: 287 YGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHML 346
G S +++AFLLS +A ++ R G V N +PIR Y V+ V
Sbjct: 318 LGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRK--IYIELICVILLTVSLFA 375
Query: 347 APLSTTYVGFCVYAGFFGFAFGWLSSVLFETLM--DLVGPQRFSSAVGLVTIVECCPVLL 404
+T + G + FFGF G + L D+VG ++ SSA G+ ++ L
Sbjct: 376 FTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLA 435
Query: 405 GPPLLGRLNDMYGDYKYTYWACGVVLIISGIYL 437
GPPL G L D Y +++C + ++ + L
Sbjct: 436 GPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCL 468
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 205 bits (522), Expect = 7e-53
Identities = 134/431 (31%), Positives = 198/431 (45%), Gaps = 50/431 (11%)
Query: 13 PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGG 72
PPDGGWGW VV+ AF + +S VFF E F + VSWI+SI +AV G
Sbjct: 7 PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFG 66
Query: 73 GPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPAL 132
P+ S L K+G R V++ GG L+ G++ ASF ++ LY+ IG++ G G A P L
Sbjct: 67 SPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTL 126
Query: 133 TMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAG 192
+ YF +RR LA GLA+ G + T AP Q + WRGS L++ L L+ G
Sbjct: 127 ACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACG 186
Query: 193 ALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQF 252
AL+RP P+ A E G + L
Sbjct: 187 ALLRP----PSLA---------EDPAVGGPRAQL-------------------------- 207
Query: 253 LDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVA 312
+L H FL Y ++ G F P + L ++ + + +AFLLS++A D+V
Sbjct: 208 --TSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVG 265
Query: 313 RPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSS 372
R G + + P + GV L P++ A +GF G L+
Sbjct: 266 RVVSGWLGDAVP--GPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAP 323
Query: 373 VLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLII 432
+ F L +L+G +R +GL+ ++E LLGPPL G L D+ G+Y ++ ++
Sbjct: 324 LAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASF-------VV 376
Query: 433 SGIYLFIGMGI 443
+G +L G GI
Sbjct: 377 AGAFLLSGSGI 387
>gi|169217968 PREDICTED: similar to solute carrier family 16, member
5 [Homo sapiens]
Length = 453
Score = 191 bits (485), Expect = 1e-48
Identities = 117/407 (28%), Positives = 205/407 (50%), Gaps = 30/407 (7%)
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P+ SILV ++G R+ +++GG L+ G++A+SF + + QLY G I GLG+ F+ ++T
Sbjct: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
Query: 134 MIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGA 193
++G YF +RR LAN LA G + + L++ GWRG+FL+ GG+ L+CC+ GA
Sbjct: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
Query: 194 LMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFL 253
++RP+ K+ E T +G + +TI + L
Sbjct: 136 IIRPVATSVAPETKECPPPPPE---------------TPALGC-----LAACGRTIQRHL 175
Query: 254 DLTLFTHR-GFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVA 312
+ H G+ +Y+ G + G P VFL Y +++A L+SI+ F ++
Sbjct: 176 AFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFL 235
Query: 313 RPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTY---VGFCVYAGFFGFAFGW 369
RP GL+A +Y F+ +++ NG+ +++ S + VG+C+ + +
Sbjct: 236 RPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCL---AYSVSMSG 292
Query: 370 LSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVV 429
+ +++F+ LMD+V +F A+GL T+++ L+ PPL G L D ++ Y ++
Sbjct: 293 IGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFF 352
Query: 430 LIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNE 476
LI + LF+G G Y L KEQ ++ E + ++ P +
Sbjct: 353 LISAA--LFMG-GSFYALQKKEQGKQAVAADALERDLFLEAKDGPGK 396
>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
Length = 471
Score = 190 bits (483), Expect = 2e-48
Identities = 129/434 (29%), Positives = 206/434 (47%), Gaps = 44/434 (10%)
Query: 13 PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGG 72
PPDGGWGW V AF G SY +S+ + F ++ F + + +WIS++ LAV
Sbjct: 32 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAA 91
Query: 73 GPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPAL 132
P+ S L ++G+R V++VGG L+ G + ++F + + LY+ +G++ G G A PAL
Sbjct: 92 SPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPAL 151
Query: 133 TMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAG 192
+ +YF +RR LA GLA+ G+ LAP Q+ FGWRG+ L+LG + L+ G
Sbjct: 152 GTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCG 211
Query: 193 ALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQF 252
AL+ P+ ++ P RS
Sbjct: 212 ALLLPL----------------------------------VLPGDPPAPPRSPLAA---- 233
Query: 253 LDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVA 312
L L+LFT R F ++ G ++ G F P V L+ + + +A ++++ A D A
Sbjct: 234 LGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGA 293
Query: 313 RPSMGLVANTKPI-RPRIQYFFAA----SVVANGVCHMLAPLSTTYVGFCVYAGFFGFAF 367
R G +A+ + PR+ F A + G+ ++ + A +G +
Sbjct: 294 RLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSA 353
Query: 368 GWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACG 427
G + ++F L LVG A GLV ++ LLGPPL G L D GD+ ++ G
Sbjct: 354 GSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSG 413
Query: 428 VVLIISGIYLFIGM 441
LI+SG +++IG+
Sbjct: 414 -SLILSGSFIYIGL 426
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 176 bits (447), Expect = 3e-44
Identities = 122/465 (26%), Positives = 204/465 (43%), Gaps = 43/465 (9%)
Query: 15 DGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGP 74
DGGW W +V+ +F ++ V E FH + +W+SS+ + + GP
Sbjct: 29 DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGP 88
Query: 75 ISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTM 134
+ +N G R I+GG ++ G + +++ V L++ GV GLG PA+ M
Sbjct: 89 FIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVM 148
Query: 135 IGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGAL 194
+G+YF KRR LA GL+ G+ + L + +GWR + LI G + LN CV GAL
Sbjct: 149 VGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGAL 208
Query: 195 MRPIGP--KPTKAGKDKSKA-----------------SLEKAGKSGVKKDLHDANT---- 231
MRP+ P P G+ + + EK G G ++ L D
Sbjct: 209 MRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECP 268
Query: 232 DLIGRHPKQEKRSVFQTIN----------------QFLDLTLFTHRGFLLYLSGNVIMFF 275
D G + +T++ F +LFT+R F+ ++ + +
Sbjct: 269 DQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYS 328
Query: 276 GLFAPLVFLSSYGKSQHYSSEKSAF-LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFA 334
P + L + S + F L SI+A V + + +G++A+ I + A
Sbjct: 329 SFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLA 388
Query: 335 ASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLV 394
+ + + PL TY G V GF+ G+ S + T DLVG + ++A G++
Sbjct: 389 NFTLVLSI--FILPLMHTYAGLAVICALIGFSSGYFSLMPVVT-EDLVGIEHLANAYGII 445
Query: 395 TIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFI 439
LLGPP G + D+ Y ++++ CG++ +I ++L I
Sbjct: 446 ICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLI 490
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 164 bits (415), Expect = 2e-40
Identities = 110/454 (24%), Positives = 205/454 (45%), Gaps = 32/454 (7%)
Query: 10 GYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFF----KEIEGIFHATTSEVSWISSIM 65
G+ PP+GG+GW VV A G + S+ + + +E + + +W+ ++
Sbjct: 165 GFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALA 224
Query: 66 LAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLA 125
+ +++ PI SI ++ G RI G ++ GL +SF +++ Y G++ G G +
Sbjct: 225 MGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCS 284
Query: 126 FNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLL 185
F P+L ++G YF +R LANG+ AGS +F + L ++ +F +L +
Sbjct: 285 FAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFM 344
Query: 186 LNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSV 245
+ RP+ P +S + K GV+ LH +
Sbjct: 345 FVLMLLSLTYRPLLP-----------SSQDTPSKRGVRT-LH---------------QRF 377
Query: 246 FQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSIL 305
+ ++ ++ +F R + ++ G G F P V L Y + + +++ LL +
Sbjct: 378 LAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCI 437
Query: 306 AFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGF 365
+ R G ++++ P +I Y S + G+ M+ PL + G V F G
Sbjct: 438 GATSGLGRLVSGHISDSIPGLKKI-YLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGL 496
Query: 366 AFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWA 425
G+ +++ +LVGP + S A+G + + P++ GPP+ G L + +GDY ++
Sbjct: 497 CDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYF 556
Query: 426 CGVVLIISGIYLFIGMGINYRLLAKEQKANEQKK 459
GV II + LF ++ R+ KEQ+ + + K
Sbjct: 557 AGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDK 590
>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
Length = 487
Score = 158 bits (400), Expect = 1e-38
Identities = 109/462 (23%), Positives = 204/462 (44%), Gaps = 41/462 (8%)
Query: 15 DGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGP 74
DGGWGW +VI F+ F K+ +FF + F T+ ++ WI SIM ++ + GP
Sbjct: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
Query: 75 ISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTM 134
+ +I+ + G + I+G + G + +S+ ++ L V +G++ GLG AF A +
Sbjct: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
Query: 135 IGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGAL 194
KYF KR L+ +A +G + LAP + ++ W G+ ++ G + LN + L
Sbjct: 136 TTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPSSML 194
Query: 195 MRPIGPKPTKAGKDKSK-ASLEKAGKSGVKKDLHDANTD--------------------- 232
+RPI K K K +SL G + H T+
Sbjct: 195 LRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTV 254
Query: 233 ----------------LIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFG 276
L+ + ++ + + + Q D++LF + F ++ ++
Sbjct: 255 SQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLA 314
Query: 277 LFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAAS 336
F P L + K+ +++L+S+ ++ V++ G VA+ I+ ++ +
Sbjct: 315 YFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKK--YHYHKSY 372
Query: 337 VVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTI 396
++ G+ ++LAPL+TT+ Y F G +++ L+DL + +GL +
Sbjct: 373 LILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASF 432
Query: 397 VECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLF 438
VL GPP+ G L D Y +++ G+ ++S + F
Sbjct: 433 FAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFF 474
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 154 bits (388), Expect = 2e-37
Identities = 115/458 (25%), Positives = 198/458 (43%), Gaps = 38/458 (8%)
Query: 13 PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSE-----VSWISSIMLA 67
PP+GGWGW V++ A G + + V F + F + + +W+ S+ +
Sbjct: 64 PPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMG 123
Query: 68 VMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFN 127
+++ PI S+ + +G R +VG + GL+++SF ++++ LY+ G+I G +F
Sbjct: 124 MIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFA 183
Query: 128 LNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLN 187
P+L ++G YF KR L NG+ AGS VF L L +V G + +L +
Sbjct: 184 YQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFV 243
Query: 188 CCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQ 247
+AG RP+ + KDK ++G SG + L R + +F
Sbjct: 244 LFLAGFTYRPL----ATSTKDK------ESGGSG---------SSLFSRKKFSPPKKIF- 283
Query: 248 TINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAF 307
+ +F + ++ G + FG F P V L + + + +L +
Sbjct: 284 ------NFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGV 337
Query: 308 VDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTY---VGFCVYAGFFG 364
V R G +A+ P ++ Y S G+ M+ PL + + + C+ G F
Sbjct: 338 TSGVGRLLFGRIADYVPGVKKV-YLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFD 396
Query: 365 FAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYW 424
G S++ +LVG Q S A+G + P+ +GPP+ G L D G Y ++
Sbjct: 397 ---GCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFY 453
Query: 425 ACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESK 462
GV +I G L I+ + + K ++K K
Sbjct: 454 LAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEK 491
>gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
Length = 509
Score = 150 bits (380), Expect = 2e-36
Identities = 125/478 (26%), Positives = 204/478 (42%), Gaps = 56/478 (11%)
Query: 14 PDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGG 73
PDGGWGW +V +F++ Y P ++ V + E F + +W+ S+ V
Sbjct: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P+ S+ V+ +G+R V I G + GL+ +SF + L+ G++ GLG +T
Sbjct: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
Query: 134 MIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGA 193
+ +YF RR LA GL GS V L A L ++ +G G LI+G L LN G+
Sbjct: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
Query: 194 LMRPIG----PKPTK---------------AGK---------DKSKASLEKA----GKSG 221
LMRP+ P P K GK DKS +S EK
Sbjct: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246
Query: 222 VKKD--LHDANTDLIGRHPKQEKRSV--------------FQTINQFLDLT--LFTHRGF 263
K+D LH T + P+ K+ V +Q + T LF ++ F
Sbjct: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306
Query: 264 LLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF-LLSILAFVDMVARPSMGLVANT 322
++ G F P + + +S + E+ L+SI+ + V + +G++A+
Sbjct: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366
Query: 323 KPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFG-WLSSVLFETLMDL 381
K I Y + A+++ G+ P + +YV + +G GF G W S+
Sbjct: 367 KWI--NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW--SIFPYVTTKT 422
Query: 382 VGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFI 439
VG ++ + A G++ LGPP++G D Y ++ G +++ G L +
Sbjct: 423 VGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480
>gi|215272392 solute carrier family 18 (vesicular monoamine), member
1 isoform c [Homo sapiens]
Length = 472
Score = 40.0 bits (92), Expect = 0.005
Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 7/142 (4%)
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P L N+ G I M G + + +F T L+V + G+G +F+ L
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSVAGLG 213
Query: 134 MIGKYFYK--RRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191
M+ + R A G A+ G + L AP V + G FLIL L L +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL---LD 270
Query: 192 GALMRPIGPKPTKAGKDKSKAS 213
GAL I +P+K + +K +
Sbjct: 271 GALQLCI-LQPSKVSPESAKGT 291
>gi|215272390 solute carrier family 18 (vesicular monoamine), member
1 isoform b [Homo sapiens]
Length = 493
Score = 40.0 bits (92), Expect = 0.005
Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 7/142 (4%)
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P L N+ G I M G + + +F T L+V + G+G +F+ L
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSVAGLG 213
Query: 134 MIGKYFYK--RRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191
M+ + R A G A+ G + L AP V + G FLIL L L +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL---LD 270
Query: 192 GALMRPIGPKPTKAGKDKSKAS 213
GAL I +P+K + +K +
Sbjct: 271 GALQLCI-LQPSKVSPESAKGT 291
>gi|208879454 solute carrier family 18 (vesicular monoamine), member
1 isoform a [Homo sapiens]
Length = 525
Score = 40.0 bits (92), Expect = 0.005
Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 7/142 (4%)
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P L N+ G I M G + + +F T L+V + G+G +F+ L
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSVAGLG 213
Query: 134 MIGKYFYK--RRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191
M+ + R A G A+ G + L AP V + G FLIL L L +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL---LD 270
Query: 192 GALMRPIGPKPTKAGKDKSKAS 213
GAL I +P+K + +K +
Sbjct: 271 GALQLCI-LQPSKVSPESAKGT 291
>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
isoform a [Homo sapiens]
Length = 525
Score = 40.0 bits (92), Expect = 0.005
Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 7/142 (4%)
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P L N+ G I M G + + +F T L+V + G+G +F+ L
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSVAGLG 213
Query: 134 MIGKYFYK--RRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191
M+ + R A G A+ G + L AP V + G FLIL L L +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL---LD 270
Query: 192 GALMRPIGPKPTKAGKDKSKAS 213
GAL I +P+K + +K +
Sbjct: 271 GALQLCI-LQPSKVSPESAKGT 291
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 35.4 bits (80), Expect = 0.12
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 450 KEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESP 499
KE+K E+++E K++E ++ K E ++ + D+ D DGG K E P
Sbjct: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE-DEDGGQKPEGEP 438
>gi|42476325 solute carrier family 18 (vesicular monoamine), member
2 [Homo sapiens]
Length = 514
Score = 33.1 bits (74), Expect = 0.60
Identities = 25/115 (21%), Positives = 47/115 (40%), Gaps = 3/115 (2%)
Query: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
P +L N+ G I + G C+ I +F ++ L + + G+G + + +
Sbjct: 147 PFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARS-LQGIGSSCSSVAGMG 205
Query: 134 MIGKYFYKRRPLAN--GLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLL 186
M+ + N G+A+ G + + P V + G FL+L L+L
Sbjct: 206 MLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 32.0 bits (71), Expect = 1.3
Identities = 13/50 (26%), Positives = 26/50 (52%)
Query: 450 KEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESP 499
+E+ A E+++E+ EE+ + + + E + K+ + GP EE P
Sbjct: 16 QEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 65
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 32.0 bits (71), Expect = 1.3
Identities = 13/50 (26%), Positives = 26/50 (52%)
Query: 450 KEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESP 499
+E+ A E+++E+ EE+ + + + E + K+ + GP EE P
Sbjct: 16 QEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 65
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 31.6 bits (70), Expect = 1.8
Identities = 12/49 (24%), Positives = 25/49 (51%)
Query: 451 EQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESP 499
E++ E+++E+ EE+ + + + E + K+ + GP EE P
Sbjct: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 31.2 bits (69), Expect = 2.3
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 451 EQKANEQKKESKEEETSIDVAGKPNEVTKAAE---SPDQKDTDGGPKEEESPV 500
E+ E++KE+KEEE + G+ E E SP ++ KE +SPV
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
>gi|31543630 solute carrier family 20 (phosphate transporter),
member 1 [Homo sapiens]
Length = 679
Score = 31.2 bits (69), Expect = 2.3
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 11/127 (8%)
Query: 329 IQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFS 388
I + A SV AN V + G V +G + + +FET+ ++ + S
Sbjct: 31 IAFVLAFSVGANDVANSF--------GTAVGSGVVTLKQACILASIFETVGSVLLGAKVS 82
Query: 389 SAV--GLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYR 446
+ GL+ VE G + G ++ M+G + A + L ISG + +G I +
Sbjct: 83 ETIRKGLID-VEMYNSTQGLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFS 141
Query: 447 LLAKEQK 453
L+AK Q+
Sbjct: 142 LVAKGQE 148
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 30.8 bits (68), Expect = 3.0
Identities = 26/110 (23%), Positives = 46/110 (41%), Gaps = 5/110 (4%)
Query: 20 WAVVIGAFISIGFSYAFPKS-ITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSI 78
+A V+G F S G++ + I + ++ H T S+ SW S+ GG + I
Sbjct: 43 FAAVLGNF-SFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMI 101
Query: 79 LVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYV---CIGVIGGLGLA 125
L + G ++ ++ S G + + + L + G GGL A
Sbjct: 102 LNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAA 151
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 30.8 bits (68), Expect = 3.0
Identities = 26/110 (23%), Positives = 46/110 (41%), Gaps = 5/110 (4%)
Query: 20 WAVVIGAFISIGFSYAFPKS-ITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSI 78
+A V+G F S G++ + I + ++ H T S+ SW S+ GG + I
Sbjct: 43 FAAVLGNF-SFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMI 101
Query: 79 LVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYV---CIGVIGGLGLA 125
L + G ++ ++ S G + + + L + G GGL A
Sbjct: 102 LNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAA 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.141 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,280,856
Number of Sequences: 37866
Number of extensions: 852247
Number of successful extensions: 3489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 3400
Number of HSP's gapped (non-prelim): 120
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.