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Search of human proteins with 23503331
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23503331 defensin, beta 123 precursor [Homo sapiens]
(67 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 152 6e-38
gi|58865339 defensin, beta 121 [Homo sapiens] 67 4e-12
gi|16905373 beta-defensin 118 [Homo sapiens] 54 3e-08
gi|116517226 beta-defensin 135 [Homo sapiens] 51 2e-07
gi|83582800 beta-defensin 116 [Homo sapiens] 47 2e-06
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 46 6e-06
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 46 7e-06
gi|83582798 beta-defensin 115 [Homo sapiens] 44 3e-05
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 42 8e-05
gi|82734223 beta-defensin 124 [Homo sapiens] 41 2e-04
gi|83582802 beta-defensin 128 [Homo sapiens] 41 2e-04
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 40 4e-04
gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo ... 35 0.010
gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo sapi... 35 0.010
gi|169173154 PREDICTED: hypothetical protein [Homo sapiens] 35 0.013
gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo sapi... 35 0.013
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 35 0.013
gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo sapi... 34 0.022
gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo sapi... 34 0.022
gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo sapi... 34 0.022
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 34 0.022
gi|50344744 beta-defensin 108B [Homo sapiens] 34 0.029
gi|18250304 beta defensin 129 precursor [Homo sapiens] 34 0.029
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens] 33 0.049
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens] 33 0.049
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens] 33 0.049
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 33 0.064
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 33 0.064
gi|149944551 defensin, beta 131 [Homo sapiens] 33 0.064
gi|82734219 beta-defensin 114 [Homo sapiens] 32 0.083
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 152 bits (384), Expect = 6e-38
Identities = 67/67 (100%), Positives = 67/67 (100%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQP 60
MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQP
Sbjct: 1 MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQP 60
Query: 61 KERWWPF 67
KERWWPF
Sbjct: 61 KERWWPF 67
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 66.6 bits (161), Expect = 4e-12
Identities = 31/60 (51%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQP 60
MKLLLL LTV LLL+Q+TP +CW G+CR C + E Y+ C CCV PKY P
Sbjct: 1 MKLLLLLLTVTLLLAQVTP--VMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVP 58
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 53.5 bits (127), Expect = 3e-08
Identities = 26/56 (46%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 1 MKLLLLTLTVLLLLSQLTPG--GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCV 54
MKLLLL L +L+LL Q+ P G ++CWN G CR +C E V C N + CC+
Sbjct: 1 MKLLLLALPMLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCI 56
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 50.8 bits (120), Expect = 2e-07
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 10/67 (14%)
Query: 4 LLLTLTVLLLLSQLTPGGT----------QRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
+LL L VL LL + PG + CW L G CR +C K E+ + C +CC
Sbjct: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
Query: 54 VKPKYQP 60
V PKY P
Sbjct: 66 VNPKYLP 72
>gi|83582800 beta-defensin 116 [Homo sapiens]
Length = 102
Score = 47.4 bits (111), Expect = 2e-06
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 12/67 (17%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGTQRC--------WN---LY-GKCRYRCSKKERVYVYCIN 48
MK L+T+ +L++L+Q TPGG R WN LY G CR C + E Y+ C N
Sbjct: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
Query: 49 NKMCCVK 55
++ CC+K
Sbjct: 64 DQKCCLK 70
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 46.2 bits (108), Expect = 6e-06
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 1 MKLLLLTLTVLLLLSQLTPGG--TQRCW-NLYGKCRYRCSKKERVYVYCINNKMCCV 54
M +L+LT + LL+++T G Q+CW N G CR RC ER + C N CC+
Sbjct: 1 MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCI 57
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 45.8 bits (107), Expect = 7e-06
Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGTQ---RCWNLYGKCRYRCSKKERVYVYCINNKMCCVK 55
MKLL L L +LL + + G + RC G CR C K E+ Y+YC N + CC++
Sbjct: 1 MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCLQ 58
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 43.9 bits (102), Expect = 3e-05
Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 1 MKLLLLTLTVLLLLSQLTPGG-TQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQ 59
+KL +L L VL++L+Q P G +RC+ G+CR C + ER C +CCV PK +
Sbjct: 13 IKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV-PKEK 71
Query: 60 PK 61
K
Sbjct: 72 DK 73
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 42.4 bits (98), Expect = 8e-05
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKY 58
MKLL L L +LL + + P + CW + G CR C E + C N K CCV +Y
Sbjct: 1 MKLLYLFLAILLAIEE--PVISVECW-MDGHCRLLCKDGEDSIIRCRNRKRCCVPSRY 55
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 41.2 bits (95), Expect = 2e-04
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGTQ--RCWNLYGKCRYRCSKKERVYVYCINNKMCC----V 54
M LLL L LL+L + G ++ RCW G C+ C+++E C + +CC +
Sbjct: 1 MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYAL 60
Query: 55 KPKYQPKERW 64
KP PK +
Sbjct: 61 KPPPVPKHEY 70
>gi|83582802 beta-defensin 128 [Homo sapiens]
Length = 93
Score = 40.8 bits (94), Expect = 2e-04
Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
Query: 1 MKLLLLTLTVLLLLSQLTPGGT-QRCWN-LYGKCRYRCSKKERVYVYCINNKMCCVKPKY 58
MKL L+ ++LL LT G ++C+N + G CR +C ER + C++ K+CC +
Sbjct: 1 MKLFLVL--IILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEE 58
Query: 59 QPK 61
+ K
Sbjct: 59 EKK 61
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 40.0 bits (92), Expect = 4e-04
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1 MKLLLLTLTVLLLLSQLTP---GGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
MK LLL L L L+Q+ P GG++ N G CR C E C ++ CC+
Sbjct: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
Query: 58 YQPK 61
+ PK
Sbjct: 61 FLPK 64
>gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo
sapiens]
Length = 70
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E V YC +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHVIRYCAYFSICC 57
>gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo
sapiens]
Length = 70
Score = 35.4 bits (80), Expect = 0.010
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICC 57
>gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]
Length = 70
Score = 35.0 bits (79), Expect = 0.013
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
>gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo
sapiens]
Length = 70
Score = 35.0 bits (79), Expect = 0.013
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 35.0 bits (79), Expect = 0.013
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 4 LLLTLTVLLLLSQLTPGGTQRCWNLY--GKCRYRCSKKERVYVYCINNKMCCVKPK 57
L + + +LL ++CWN Y G CR C E C N + CC+ K
Sbjct: 3 LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIK 58
>gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo
sapiens]
Length = 70
Score = 34.3 bits (77), Expect = 0.022
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
>gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo
sapiens]
Length = 70
Score = 34.3 bits (77), Expect = 0.022
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
>gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo
sapiens]
Length = 70
Score = 34.3 bits (77), Expect = 0.022
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+S + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 34.3 bits (77), Expect = 0.022
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1 MKLLLLTLTVLLLLSQLTPGG---TQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
M++ +L + +SQ+ P + C G CR C + E C+N++ CC+
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 60
Query: 58 YQPK 61
+QP+
Sbjct: 61 HQPR 64
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 33.9 bits (76), Expect = 0.029
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1 MKLLLLTLTVLLLLSQLTPGG---TQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
M++ +L + +SQ+ P + C G CR C + E C+N++ CC+
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCLPLG 60
Query: 58 YQPK 61
+QP+
Sbjct: 61 HQPR 64
>gi|18250304 beta defensin 129 precursor [Homo sapiens]
Length = 183
Score = 33.9 bits (76), Expect = 0.029
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 1 MKLLLLTLTVLLLLSQLTPG--GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
MKLL L+L Q+ G +RC G+CR C+ E+ C K CCV PK
Sbjct: 1 MKLLFPIFASLMLQYQVNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKC-KMKKCCVGPK 58
>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 33.1 bits (74), Expect = 0.049
Identities = 12/30 (40%), Positives = 15/30 (50%)
Query: 25 CWNLYGKCRYRCSKKERVYVYCINNKMCCV 54
CW + G CR C E+V C N CC+
Sbjct: 18 CWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 33.1 bits (74), Expect = 0.049
Identities = 12/30 (40%), Positives = 15/30 (50%)
Query: 25 CWNLYGKCRYRCSKKERVYVYCINNKMCCV 54
CW + G CR C E+V C N CC+
Sbjct: 18 CWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 33.1 bits (74), Expect = 0.049
Identities = 12/30 (40%), Positives = 15/30 (50%)
Query: 25 CWNLYGKCRYRCSKKERVYVYCINNKMCCV 54
CW + G CR C E+V C N CC+
Sbjct: 18 CWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 32.7 bits (73), Expect = 0.064
Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1 MKLLLLTLTVLLLLSQLTPGG---TQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
+++ +L + +SQ+ P + C G CR C + E C+N++ CC+
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 70
Query: 58 YQPK 61
+QP+
Sbjct: 71 HQPR 74
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 32.7 bits (73), Expect = 0.064
Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1 MKLLLLTLTVLLLLSQLTPGG---TQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
+++ +L + +SQ+ P + C G CR C + E C+N++ CC+
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 70
Query: 58 YQPK 61
+QP+
Sbjct: 71 HQPR 74
>gi|149944551 defensin, beta 131 [Homo sapiens]
Length = 70
Score = 32.7 bits (73), Expect = 0.064
Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 1 MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
M++L VL L+ + P C + Y CR +C+ E YC + +CC
Sbjct: 1 MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
>gi|82734219 beta-defensin 114 [Homo sapiens]
Length = 69
Score = 32.3 bits (72), Expect = 0.083
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 3 LLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYC-INNKMCCVKPKYQ 59
L L +L + T RC YG+C+ C + E+ C + K+CC + Y+
Sbjct: 7 LHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYE 64
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.142 0.515
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,967,209
Number of Sequences: 37866
Number of extensions: 107358
Number of successful extensions: 356
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 314
Number of HSP's gapped (non-prelim): 49
length of query: 67
length of database: 18,247,518
effective HSP length: 40
effective length of query: 27
effective length of database: 16,732,878
effective search space: 451787706
effective search space used: 451787706
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.