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Search of human proteins with 23312378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23312378 protein phosphatase with EF hand calcium-binding
domain 1 isoform 3 [Homo sapiens]
(591 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 1202 0.0
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 1123 0.0
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 735 0.0
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 334 2e-91
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 171 2e-42
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 103 3e-22
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 103 3e-22
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 103 4e-22
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 103 4e-22
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 102 1e-21
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 102 1e-21
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 102 1e-21
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 100 6e-21
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 99 1e-20
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 99 1e-20
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 99 1e-20
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 99 1e-20
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 98 2e-20
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 98 2e-20
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 98 2e-20
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 95 2e-19
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 91 2e-18
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 86 7e-17
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 86 7e-17
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 67 6e-11
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 50 6e-06
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 50 6e-06
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 50 6e-06
gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens] 44 4e-04
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 42 0.001
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 1202 bits (3110), Expect = 0.0
Identities = 591/591 (100%), Positives = 591/591 (100%)
Query: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS
Sbjct: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
Query: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD
Sbjct: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
Query: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIF 360
ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIF
Sbjct: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIF 360
Query: 361 SASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVI 420
SASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVI
Sbjct: 361 SASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVI 420
Query: 421 SRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMS 480
SRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMS
Sbjct: 421 SRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMS 480
Query: 481 SFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHY 540
SFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHY
Sbjct: 481 SFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHY 540
Query: 541 NVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 591
NVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
Sbjct: 541 NVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 591
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 1123 bits (2904), Expect = 0.0
Identities = 568/625 (90%), Positives = 573/625 (91%), Gaps = 34/625 (5%)
Query: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS
Sbjct: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
Query: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD
Sbjct: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
Query: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTE-------------- 346
ERNKMKSVLIPPTETNRDHDTDSKHNK+ + R K P
Sbjct: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTS 360
Query: 347 ----------HLTEHEWE----------QVVTIFSASNYYEEGSNRGAYIKLCSGTTPRF 386
+ HE + +VVTIFSASNYYEEGSNRGAYIKLCSGTTPRF
Sbjct: 361 KILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRF 420
Query: 387 FQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQW 446
FQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQW
Sbjct: 421 FQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQW 480
Query: 447 AFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYR 506
AFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYR
Sbjct: 481 AFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYR 540
Query: 507 SDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDF 566
SDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDF
Sbjct: 541 SDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDF 600
Query: 567 NEFLKAFYVVHRYEDLMKPDVTNLG 591
NEFLKAFYVVHRYEDLMKPDVTNLG
Sbjct: 601 NEFLKAFYVVHRYEDLMKPDVTNLG 625
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 735 bits (1898), Expect = 0.0
Identities = 359/381 (94%), Positives = 364/381 (95%), Gaps = 4/381 (1%)
Query: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS
Sbjct: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
Query: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD
Sbjct: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
Query: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIF 360
ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQ++ I
Sbjct: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDIL 360
Query: 361 SASNYYEEGSNRGAYIKLCSG 381
+ + G + C G
Sbjct: 361 ----WSDPRGKNGCFPNTCRG 377
Score = 476 bits (1225), Expect = e-134
Identities = 236/237 (99%), Positives = 237/237 (100%)
Query: 355 QVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI 414
+VVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI
Sbjct: 417 KVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI 476
Query: 415 LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG 474
LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG
Sbjct: 477 LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG 536
Query: 475 NVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWK 534
NVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWK
Sbjct: 537 NVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWK 596
Query: 535 LFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 591
LFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
Sbjct: 597 LFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 653
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 334 bits (856), Expect = 2e-91
Identities = 160/319 (50%), Positives = 225/319 (70%), Gaps = 6/319 (1%)
Query: 11 RRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENY 70
+ ++ + +AA +IQ WYR Y ARL+ R+ +IFQSIEYA +Q Q++L FFS++++++
Sbjct: 14 QNAERAFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHF 73
Query: 71 ---THIHKEELE--LRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLL 125
+H ++ L + +M+ DY +SI+VPDSY GPRL FPL L+
Sbjct: 74 IPSSHNDRDFLTRIFTEDRFAQDSEMKKCSDY-ESIEVPDSYTGPRLSFPLLPDHATALV 132
Query: 126 EAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFY 185
EAF+ +Q LHA YVL +L+ETKK L Q+PN + T S+E+T+CGDLHG+LDDL IFY
Sbjct: 133 EAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFY 192
Query: 186 KNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGF 245
KNGLPS YVFNGDFVDRGK+S+EILMIL LVYP + HLNRGNHED M+NLRYGF
Sbjct: 193 KNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGF 252
Query: 246 TKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKM 305
TKE+++KYK+HGK IL+ L++ + WLP+ T++D ++L++HGG+S+ TDL LL ++ER+K+
Sbjct: 253 TKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITDLELLDKIERSKI 312
Query: 306 KSVLIPPTETNRDHDTDSK 324
S + T + + K
Sbjct: 313 VSTMRCKTRQKSEKQMEEK 331
Score = 218 bits (554), Expect = 2e-56
Identities = 113/225 (50%), Positives = 149/225 (66%), Gaps = 1/225 (0%)
Query: 355 QVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI 414
+V+TIFSASNYYE GSNRGAY+KL TP QYQ K T +RQR+ +E SA++
Sbjct: 502 KVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQRISRVEESALRA 561
Query: 415 LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG 474
LRE++ + SDL F+ D K G +++S WA +E++L L LPWR L LVN +
Sbjct: 562 LREKLFAHSSDLLSEFKKHDADKVGLITLSDWAAAVESVLHLGLPWRMLRPQLVNSSADN 621
Query: 475 NVEYMSSFQNIRIEKPVQE-AHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMW 533
+EY S +N+ E+ +E S+L+ETLYR RS+LE IF ID+DHSG IS++EFR W
Sbjct: 622 MLEYKSWLKNLAKEQLSRENIQSSLLETLYRNRSNLETIFRIIDSDHSGFISLDEFRQTW 681
Query: 534 KLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHR 578
KLFSSH N+ I D + LA +D NKDG ID NEFL+AF +V +
Sbjct: 682 KLFSSHMNIDITDDCICDLARSIDFNKDGHIDINEFLEAFRLVEK 726
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 171 bits (432), Expect = 2e-42
Identities = 103/342 (30%), Positives = 176/342 (51%), Gaps = 37/342 (10%)
Query: 86 ESEQDMRDRWDYVDSIDVPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLF 144
E ++ + D D ++S+ + D Y+GP+L+ +T + + L++ +K+Q+ LH ++L
Sbjct: 156 EHKRSVVDSLD-IESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILV 214
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
+ K+VL ++ ++++T+CGD HG+ DL IF NGLPSE NPY+FNGDFVD
Sbjct: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG S+E+++ L L+YP+ HL RGNHE MN YGF E+ KY ++ ++
Sbjct: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT---AQMYELF 331
Query: 265 EEFYAWLPIGTIVDNEILVIHGGI--SETTDLNLLHRVERNK-------MKSVLIPPTET 315
E + WLP+ ++ ++L++HGG+ + L+ + ++ERN+ M +L +
Sbjct: 332 SEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQP 391
Query: 316 NRDHDTDSK----------------HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTI 359
+ N + +H +K G H + VT+
Sbjct: 392 QNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSH-EVKAEGYEVAH-----GGRCVTV 445
Query: 360 FSASNYYEEGSNRGAYIKL-CSGTTPRFFQYQVTKATCFQPL 400
FSA NY ++ N+ +YI L S P+F Q+ +P+
Sbjct: 446 FSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPM 487
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 103 bits (258), Expect = 3e-22
Identities = 81/288 (28%), Positives = 132/288 (45%), Gaps = 25/288 (8%)
Query: 120 DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDD 179
++D +E E + L+ + V + + K++L + N ++ VT+CGD+HG+ D
Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHD 64
Query: 180 LFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM 239
L +F G + N Y+F GD+VDRG S+E + +L + YP + + RGNHE +
Sbjct: 65 LMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI 123
Query: 240 NLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD------ 293
YGF E L KY + + + + +LP+ +VD +I +HGG+S + D
Sbjct: 124 TQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIR 181
Query: 294 -LNLLHRVERNKMKSVLIPPTETNRDHDTDSKH-------NKVGVTFN-AHGRIKTNGSP 344
L+ L V L+ +R S + TFN A+G + +
Sbjct: 182 ALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAH 241
Query: 345 TEHLTEHEW---EQVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQY 389
+ + W VVTIFSA NY N+ A ++L F Q+
Sbjct: 242 QLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF 289
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 103 bits (258), Expect = 3e-22
Identities = 81/288 (28%), Positives = 132/288 (45%), Gaps = 25/288 (8%)
Query: 120 DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDD 179
++D +E E + L+ + V + + K++L + N ++ VT+CGD+HG+ D
Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHD 64
Query: 180 LFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM 239
L +F G + N Y+F GD+VDRG S+E + +L + YP + + RGNHE +
Sbjct: 65 LMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI 123
Query: 240 NLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD------ 293
YGF E L KY + + + + +LP+ +VD +I +HGG+S + D
Sbjct: 124 TQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIR 181
Query: 294 -LNLLHRVERNKMKSVLIPPTETNRDHDTDSKH-------NKVGVTFN-AHGRIKTNGSP 344
L+ L V L+ +R S + TFN A+G + +
Sbjct: 182 ALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAH 241
Query: 345 TEHLTEHEW---EQVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQY 389
+ + W VVTIFSA NY N+ A ++L F Q+
Sbjct: 242 QLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF 289
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 103 bits (257), Expect = 4e-22
Identities = 76/237 (32%), Positives = 111/237 (46%), Gaps = 39/237 (16%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 72 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 130
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 131 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 187
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETN----------RDHDTDSK---HNKVGVTFNAH 335
S DL + ++ R ++ PT+ D D D + N GV+F
Sbjct: 188 S--PDLQSMEQIRR------IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFG 239
Query: 336 GRIKTNG---------SPTEHLTEHEWE-----QVVTIFSASNYYEEGSNRGAYIKL 378
+ + E +E Q+VT+FSA NY E N GA + +
Sbjct: 240 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 296
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 103 bits (257), Expect = 4e-22
Identities = 76/237 (32%), Positives = 111/237 (46%), Gaps = 39/237 (16%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETN----------RDHDTDSK---HNKVGVTFNAH 335
S DL + ++ R ++ PT+ D D D + N GV+F
Sbjct: 177 S--PDLQSMEQIRR------IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFG 228
Query: 336 GRIKTNG---------SPTEHLTEHEWE-----QVVTIFSASNYYEEGSNRGAYIKL 378
+ + E +E Q+VT+FSA NY E N GA + +
Sbjct: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 285
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 102 bits (254), Expect = 1e-21
Identities = 76/232 (32%), Positives = 113/232 (48%), Gaps = 29/232 (12%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRD-HDTDSKHNKVGVTFNAHGRIKTNGSP--T 345
S DL + ++ R M+ +P D +D + +G N G T G+
Sbjct: 177 S--PDLQSMEQI-RRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVA 233
Query: 346 EHLTEHEWE-------------------QVVTIFSASNYYEEGSNRGAYIKL 378
+ L +H+ + Q+VT+FSA NY E N GA + +
Sbjct: 234 KFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 285
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 102 bits (254), Expect = 1e-21
Identities = 74/237 (31%), Positives = 112/237 (47%), Gaps = 39/237 (16%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTE-------TNRDHDTDS-KHNKVGVTFNAHGRIKT 340
S DL + ++ R M+ +P T ++ D D N GV+F +
Sbjct: 176 S--PDLQSMEQI-RRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADV-- 230
Query: 341 NGSPTEHLTEHEWE-------------------QVVTIFSASNYYEEGSNRGAYIKL 378
++ L H+ + Q+VT+FSA NY E N G + +
Sbjct: 231 ---VSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 284
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 102 bits (254), Expect = 1e-21
Identities = 74/237 (31%), Positives = 112/237 (47%), Gaps = 39/237 (16%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTE-------TNRDHDTDS-KHNKVGVTFNAHGRIKT 340
S DL + ++ R M+ +P T ++ D D N GV+F +
Sbjct: 176 S--PDLQSMEQI-RRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADV-- 230
Query: 341 NGSPTEHLTEHEWE-------------------QVVTIFSASNYYEEGSNRGAYIKL 378
++ L H+ + Q+VT+FSA NY E N G + +
Sbjct: 231 ---VSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 284
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 99.8 bits (247), Expect = 6e-21
Identities = 80/288 (27%), Positives = 129/288 (44%), Gaps = 25/288 (8%)
Query: 120 DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDD 179
++D +E E + L V + + K++L + N ++ VT+CGD+HG+ D
Sbjct: 9 ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHD 64
Query: 180 LFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM 239
L +F G + N Y+F GD+VDRG S+E + +L + Y + + RGNHE +
Sbjct: 65 LMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQI 123
Query: 240 NLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD------ 293
YGF E L KY + + + + +LP+ +VD +I +HGG+S + D
Sbjct: 124 TQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIR 181
Query: 294 -LNLLHRVERNKMKSVLIPPTETNRDHDTDSKH-------NKVGVTFN-AHGRIKTNGSP 344
L+ L V L+ +R S + TFN A+G + +
Sbjct: 182 ALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAH 241
Query: 345 TEHLTEHEW---EQVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQY 389
+ + W VVTIFSA NY N+ A ++L F Q+
Sbjct: 242 QLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF 289
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 99.0 bits (245), Expect = 1e-20
Identities = 76/289 (26%), Positives = 126/289 (43%), Gaps = 40/289 (13%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
Query: 300 VERNKMKSVLIP-------------PTETNRDHDTDS------------------KHNKV 328
++R K P E ++H T + +HN +
Sbjct: 215 LDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNL 274
Query: 329 GVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNYYEEGSNRGAYIK 377
AH + ++TIFSA NY + +N+ A +K
Sbjct: 275 LSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 323
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 99.0 bits (245), Expect = 1e-20
Identities = 76/289 (26%), Positives = 126/289 (43%), Gaps = 40/289 (13%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
Query: 300 VERNKMKSVLIP-------------PTETNRDHDTDS------------------KHNKV 328
++R K P E ++H T + +HN +
Sbjct: 215 LDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNL 274
Query: 329 GVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNYYEEGSNRGAYIK 377
AH + ++TIFSA NY + +N+ A +K
Sbjct: 275 LSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 323
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 98.6 bits (244), Expect = 1e-20
Identities = 77/278 (27%), Positives = 129/278 (46%), Gaps = 25/278 (8%)
Query: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178
+D+D +E + +++ V + + +++L + N + + VT+CGD+HG+
Sbjct: 5 SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60
Query: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238
DL +F G E N Y+F GDFVDRG S+E ++L + YP+ + L RGNHE
Sbjct: 61 DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119
Query: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297
+ YGF E L KY + + E + +L + I+D +I +HGG+S + L+ +
Sbjct: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177
Query: 298 HRVERNK-------MKSVLIPPTETNRDHDTDSK------HNKVGVTFNAHGRI----KT 340
++R + M +L E + + V FNA I +
Sbjct: 178 RTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRA 237
Query: 341 NGSPTEHLTEHEWEQVVTIFSASNYYEEGSNRGAYIKL 378
+ E H E V+T++SA NY N A ++L
Sbjct: 238 HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL 275
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 98.6 bits (244), Expect = 1e-20
Identities = 74/235 (31%), Positives = 109/235 (46%), Gaps = 39/235 (16%)
Query: 171 GDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLN 230
GD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP + L
Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 77
Query: 231 RGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISE 290
RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+S
Sbjct: 78 RGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLS- 133
Query: 291 TTDLNLLHRVERNKMKSVLIPPTETN----------RDHDTDSK---HNKVGVTFNAHGR 337
DL + ++ R ++ PT+ D D D + N GV+F
Sbjct: 134 -PDLQSMEQIRR------IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAE 186
Query: 338 IKTNG---------SPTEHLTEHEWE-----QVVTIFSASNYYEEGSNRGAYIKL 378
+ + E +E Q+VT+FSA NY E N GA + +
Sbjct: 187 VVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 241
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 97.8 bits (242), Expect = 2e-20
Identities = 77/289 (26%), Positives = 131/289 (45%), Gaps = 40/289 (13%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ + L ++ E +L++ ++ +T+CGD+HG+ DL
Sbjct: 52 VDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDL 107
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L V ++YP+ L L RGNHE +
Sbjct: 108 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLT 166
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + E + LP+ +++ + L +HGG+S E L+ + R
Sbjct: 167 EYFTFKQECKIKY---SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRR 223
Query: 300 VERNKMKSVLIP--------PTET--NRDHDTDSKHNKVG-----VTFNAHGRIKTNGSP 344
++R K P P+E N HN V + A N +
Sbjct: 224 LDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNL 283
Query: 345 TEHLTEHE----------------WEQVVTIFSASNYYEEGSNRGAYIK 377
+ HE + ++TIFSA NY + +N+ A +K
Sbjct: 284 LSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 332
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 97.8 bits (242), Expect = 2e-20
Identities = 77/289 (26%), Positives = 131/289 (45%), Gaps = 40/289 (13%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ + L ++ E +L++ ++ +T+CGD+HG+ DL
Sbjct: 52 VDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDL 107
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L V ++YP+ L L RGNHE +
Sbjct: 108 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLT 166
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + E + LP+ +++ + L +HGG+S E L+ + R
Sbjct: 167 EYFTFKQECKIKY---SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRR 223
Query: 300 VERNKMKSVLIP--------PTET--NRDHDTDSKHNKVG-----VTFNAHGRIKTNGSP 344
++R K P P+E N HN V + A N +
Sbjct: 224 LDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNL 283
Query: 345 TEHLTEHE----------------WEQVVTIFSASNYYEEGSNRGAYIK 377
+ HE + ++TIFSA NY + +N+ A +K
Sbjct: 284 LSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 332
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 97.8 bits (242), Expect = 2e-20
Identities = 77/289 (26%), Positives = 131/289 (45%), Gaps = 40/289 (13%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ + L ++ E +L++ ++ +T+CGD+HG+ DL
Sbjct: 52 VDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDL 107
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L V ++YP+ L L RGNHE +
Sbjct: 108 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLT 166
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + E + LP+ +++ + L +HGG+S E L+ + R
Sbjct: 167 EYFTFKQECKIKY---SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRR 223
Query: 300 VERNKMKSVLIP--------PTET--NRDHDTDSKHNKVG-----VTFNAHGRIKTNGSP 344
++R K P P+E N HN V + A N +
Sbjct: 224 LDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNL 283
Query: 345 TEHLTEHE----------------WEQVVTIFSASNYYEEGSNRGAYIK 377
+ HE + ++TIFSA NY + +N+ A +K
Sbjct: 284 LSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 332
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 95.1 bits (235), Expect = 2e-19
Identities = 74/284 (26%), Positives = 123/284 (43%), Gaps = 40/284 (14%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
Query: 300 VERNKMKSVLIP-------------PTETNRDHDTDS------------------KHNKV 328
++R K P E ++H T + +HN +
Sbjct: 215 LDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNL 274
Query: 329 GVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNYYEEGSNR 372
AH + ++TIFSA NY + +N+
Sbjct: 275 LSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK 318
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 91.3 bits (225), Expect = 2e-18
Identities = 70/289 (24%), Positives = 127/289 (43%), Gaps = 40/289 (13%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L+++ + +L+Q + +T+CGD+HG+ DL
Sbjct: 39 VDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCGDIHGQFFDL 94
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G PS Y+F GD+VDRG SIE ++ L + +P L L RGNHE +
Sbjct: 95 MKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLT 153
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +++ E + LP+ +++ + L +HGG+S E T L+ + +
Sbjct: 154 DYFTFKQECRIKY---SEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRK 210
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIK---------------TNGSP 344
++R P + ++ N+ + H ++ N +
Sbjct: 211 LDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNL 270
Query: 345 TEHLTEHE----------------WEQVVTIFSASNYYEEGSNRGAYIK 377
+ HE + ++TIFSA NY + +N+ A +K
Sbjct: 271 LSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLK 319
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 86.3 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 75/142 (52%), Gaps = 4/142 (2%)
Query: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 82 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 140
Query: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 141 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 198
Query: 284 IHGGIS-ETTDLNLLHRVERNK 304
+HGG+S + L+ + +ERN+
Sbjct: 199 VHGGLSPDIKTLDQIRTIERNQ 220
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 86.3 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 75/142 (52%), Gaps = 4/142 (2%)
Query: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 45 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 103
Query: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 104 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 161
Query: 284 IHGGIS-ETTDLNLLHRVERNK 304
+HGG+S + L+ + +ERN+
Sbjct: 162 VHGGLSPDIKTLDQIRTIERNQ 183
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 66.6 bits (161), Expect = 6e-11
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 26/142 (18%)
Query: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
S VT+CGD+HG+ GDFVDRG S+E L +
Sbjct: 45 STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81
Query: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 82 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 139
Query: 284 IHGGIS-ETTDLNLLHRVERNK 304
+HGG+S + L+ + +ERN+
Sbjct: 140 VHGGLSPDIKTLDQIRTIERNQ 161
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 50.1 bits (118), Expect = 6e-06
Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 66/232 (28%)
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 265
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTD-------LNLLHRV-ERNKMKSVLIPPTETN 316
D ++ +HGG+S + D LN L ++ M +L +
Sbjct: 266 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD-- 314
Query: 317 RDHDTDSKHNKVG---VTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNY 365
DHDT N + AH + H H+W VV IFS NY
Sbjct: 315 -DHDTPETFNHASGLRLVSRAHQLVMVG-----HNWCHDW-NVVAIFSTPNY 359
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 50.1 bits (118), Expect = 6e-06
Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 66/232 (28%)
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTD-------LNLLHRV-ERNKMKSVLIPPTETN 316
D ++ +HGG+S + D LN L ++ M +L +
Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD-- 193
Query: 317 RDHDTDSKHNKVG---VTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNY 365
DHDT N + AH + H H+W VV IFS NY
Sbjct: 194 -DHDTPETFNHASGLRLVSRAHQLVMVG-----HNWCHDW-NVVAIFSTPNY 238
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 50.1 bits (118), Expect = 6e-06
Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 66/232 (28%)
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTD-------LNLLHRV-ERNKMKSVLIPPTETN 316
D ++ +HGG+S + D LN L ++ M +L +
Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD-- 193
Query: 317 RDHDTDSKHNKVG---VTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNY 365
DHDT N + AH + H H+W VV IFS NY
Sbjct: 194 -DHDTPETFNHASGLRLVSRAHQLVMVG-----HNWCHDW-NVVAIFSTPNY 238
>gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens]
Length = 370
Score = 43.9 bits (102), Expect = 4e-04
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 11/174 (6%)
Query: 399 PLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNL 458
P R+ M +SA R +L AF+ D K G ++ CM + +
Sbjct: 203 PFLHRLRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPT 262
Query: 459 PWRSLS-SNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAID 517
+ S +N++ G+V++ F + K + E + +L F D
Sbjct: 263 EMELIELSQQINMNLGGHVDF-DDFVELMGPKLLAETADMIGV------KELRDAFREFD 315
Query: 518 TDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLK 571
T+ G IS E R + H H D + ++ +DLN DG +DF EF++
Sbjct: 316 TNGDGEISTSELREAMRKLLGHQVGHRD---IEEIIRDVDLNGDGRVDFEEFVR 366
>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/66 (27%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 513 FNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKA 572
F+ D D G I++ + + + + NV +D++ ++++ N +DLNK+G ++ NEFL+
Sbjct: 632 FHKFDADQKGFITIVDVQRVLESI----NVQMDENTLHEILNEVDLNKNGQVELNEFLQL 687
Query: 573 FYVVHR 578
+ +
Sbjct: 688 MSAIQK 693
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,344,648
Number of Sequences: 37866
Number of extensions: 925325
Number of successful extensions: 2580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 2290
Number of HSP's gapped (non-prelim): 301
length of query: 591
length of database: 18,247,518
effective HSP length: 108
effective length of query: 483
effective length of database: 14,157,990
effective search space: 6838309170
effective search space used: 6838309170
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.