Guide to the Human Genome
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Search of human proteins with 23308563

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23308563 hypothetical protein LOC221301 [Homo sapiens]
         (128 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23308563 hypothetical protein LOC221301 [Homo sapiens]             271   8e-74
gi|21361521 calcium homeostasis modulator 2 [Homo sapiens]             67   4e-12
gi|62988336 hypothetical protein LOC441168 [Homo sapiens]              58   2e-09
gi|24308454 hypothetical protein LOC254228 [Homo sapiens]              46   9e-06
gi|194440685 calcium homeostasis modulator 1 [Homo sapiens]            43   8e-05
gi|193211395 calcium homeostasis modulator 3 [Homo sapiens]            43   8e-05
gi|38490587 keratin associated protein 10-12 [Homo sapiens]            28   2.6  
gi|55749742 HEAT repeat containing 5B [Homo sapiens]                   27   3.3  
gi|62988328 ankyrin repeat domain 50 [Homo sapiens]                    27   3.3  
gi|238231397 coiled-coil domain containing 12 [Homo sapiens]           27   5.7  
gi|226371669 discs large homolog 7 isoform b [Homo sapiens]            27   5.7  
gi|226371667 discs large homolog 7 isoform a [Homo sapiens]            27   5.7  
gi|15082228 keratin associated protein 4-2 [Homo sapiens]              26   7.4  
gi|60593036 keratin associated protein 5-3 [Homo sapiens]              26   7.4  
gi|154146260 keratin associated protein 4-3 [Homo sapiens]             26   7.4  
gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]      26   9.7  
gi|239758034 PREDICTED: keratin associated protein 4-8 isoform 3...    26   9.7  
gi|239758032 PREDICTED: keratin associated protein 4-8 isoform 2...    26   9.7  
gi|239758030 PREDICTED: keratin associated protein 4-8 isoform 1...    26   9.7  
gi|239756798 PREDICTED: similar to keratin associated protein 4-...    26   9.7  
gi|239756796 PREDICTED: similar to keratin associated protein 4-...    26   9.7  
gi|239756794 PREDICTED: similar to keratin associated protein 4-...    26   9.7  
gi|239751306 PREDICTED: keratin associated protein 4-8 [Homo sap...    26   9.7  
gi|239745805 PREDICTED: keratin associated protein 4.8 [Homo sap...    26   9.7  
gi|225690554 keratin associated protein 4.8 [Homo sapiens]             26   9.7  
gi|4826948 protein kinase, X-linked [Homo sapiens]                     26   9.7  
gi|60279697 keratin associated protein 5-7 [Homo sapiens]              26   9.7  
gi|123702038 keratin associated protein 5-9 [Homo sapiens]             26   9.7  
gi|60593038 keratin associated protein 5-4 [Homo sapiens]              26   9.7  

>gi|23308563 hypothetical protein LOC221301 [Homo sapiens]
          Length = 128

 Score =  271 bits (694), Expect = 8e-74
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 1   MLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMH 60
           MLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMH
Sbjct: 1   MLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMH 60

Query: 61  RIKKLFGFIPGSEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEEDR 120
           RIKKLFGFIPGSEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEEDR
Sbjct: 61  RIKKLFGFIPGSEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEEDR 120

Query: 121 SRGIELKP 128
           SRGIELKP
Sbjct: 121 SRGIELKP 128


>gi|21361521 calcium homeostasis modulator 2 [Homo sapiens]
          Length = 323

 Score = 67.0 bits (162), Expect = 4e-12
 Identities = 27/74 (36%), Positives = 46/74 (62%)

Query: 1   MLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMH 60
           + GW+LI +  I   ++ C+   CSPL+  Q  YW  +  NE +LF++ AE HSR+L  +
Sbjct: 186 LFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAAN 245

Query: 61  RIKKLFGFIPGSED 74
            +++ FGF+  ++D
Sbjct: 246 NVRRFFGFVALNKD 259


>gi|62988336 hypothetical protein LOC441168 [Homo sapiens]
          Length = 315

 Score = 57.8 bits (138), Expect = 2e-09
 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 4/90 (4%)

Query: 1   MLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMH 60
           +LGWILI +  I  L+   V +C SP++ LQ  +W  +L+ E+++ +  A +H+  L   
Sbjct: 176 VLGWILIAVVIIILLIFTSVTRCLSPVSFLQLKFWKIYLEQEQQILKSKATEHATELAKE 235

Query: 61  RIKKLFGFIPGSEDVKHIRIPSCQDWKDIS 90
            IK    F  GS   K    PS ++W+ IS
Sbjct: 236 NIK---CFFEGSHP-KEYNTPSMKEWQQIS 261


>gi|24308454 hypothetical protein LOC254228 [Homo sapiens]
          Length = 309

 Score = 45.8 bits (107), Expect = 9e-06
 Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 15/128 (11%)

Query: 1   MLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMH 60
           +LGW LI  A+  +L++ C A+C S ++ LQ  +W ++ Q E+E  E     ++  L   
Sbjct: 181 ILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQKEKEQLENTFLDYANKLSER 240

Query: 61  RIKKLFGFIPGSEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEEDR 120
            +K  F     ++      +P+   W+  S    L      Q HYS L   VD       
Sbjct: 241 NLKCFF----ENKRPDPFPMPTFAAWEAASE---LHSFHQSQQHYSTLHRVVD------- 286

Query: 121 SRGIELKP 128
             G++L P
Sbjct: 287 -NGLQLSP 293


>gi|194440685 calcium homeostasis modulator 1 [Homo sapiens]
          Length = 346

 Score = 42.7 bits (99), Expect = 8e-05
 Identities = 19/65 (29%), Positives = 34/65 (52%)

Query: 2   LGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMHR 61
           LGW  + L T+ A V   V  C +    L+  YW+ ++  ER+LF++   +H++      
Sbjct: 187 LGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVC 246

Query: 62  IKKLF 66
           I++ F
Sbjct: 247 IQQFF 251


>gi|193211395 calcium homeostasis modulator 3 [Homo sapiens]
          Length = 344

 Score = 42.7 bits (99), Expect = 8e-05
 Identities = 17/54 (31%), Positives = 32/54 (59%)

Query: 2   LGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSR 55
           +GW +  L  IAA ++ C+  C      LQ  YW++++  E++LF++   +H+R
Sbjct: 183 IGWSVTLLLIIAAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHAR 236


>gi|38490587 keratin associated protein 10-12 [Homo sapiens]
          Length = 245

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 21/80 (26%), Positives = 30/80 (37%), Gaps = 8/80 (10%)

Query: 17  SCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMHRIKKLFGFIPGSEDVK 76
           SCCV  CC P+  +  C   S L  ++   + A    S       +  L    P     +
Sbjct: 150 SCCVPVCCKPICCVPVCSGASSLCCQQSSCQPACCTTSCCRPSSSVSLLCR--PVCRPAR 207

Query: 77  HIRIPSCQDWKDISVPTLLC 96
            + +PSC       VPT  C
Sbjct: 208 RVPVPSC------CVPTSSC 221


>gi|55749742 HEAT repeat containing 5B [Homo sapiens]
          Length = 2071

 Score = 27.3 bits (59), Expect = 3.3
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 16  VSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMHRIKKLFGFI 69
           V C VAKC   L +     WT+ L+N   L  +A E +S   +   + KL G +
Sbjct: 193 VRCAVAKCLLELQNEAVFMWTAELENIATLCFKALE-NSNYGVRVAVSKLLGTV 245


>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
          Length = 1429

 Score = 27.3 bits (59), Expect = 3.3
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 20  VAKCCSPLT--SLQHCYWTSHLQNERELFEQAAEQHSRLLM--MHRIKKLF--GFIPGSE 73
           +   C PLT   L H  WT ++    E F++  +  S+LL+  +   K LF   F     
Sbjct: 357 ILAACRPLTITELYHAVWTKNMSLTLEDFQRKLDILSKLLVDGLGNTKILFHYSFAEWLL 416

Query: 74  DVKH 77
           DVKH
Sbjct: 417 DVKH 420


>gi|238231397 coiled-coil domain containing 12 [Homo sapiens]
          Length = 179

 Score = 26.6 bits (57), Expect = 5.7
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 11/49 (22%)

Query: 36 TSHLQNERELFEQAAEQHSRLLMMHRIKKLFGFIPGSEDVKHIRIPSCQ 84
          T HL+ E E  E+           HR  +L  ++P  ED+K  R+P  +
Sbjct: 54 TKHLREEEEEGEK-----------HRELRLRNYVPEDEDLKKRRVPQAK 91


>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
          Length = 842

 Score = 26.6 bits (57), Expect = 5.7
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 32  HCY-WTSHLQ-----NERELFEQAAEQHSRLLMMHRIKKLFGFIPGSEDVKHIRIPSCQD 85
           HC+ W   L+     + ++L   A  Q +RLLM  R K+  G +   E  + I+  +C D
Sbjct: 447 HCFEWDRKLELDIPDDAKDLIRTAVGQ-TRLLMKERFKQFEGLVDDCEYKRGIKETTCTD 505


>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
          Length = 846

 Score = 26.6 bits (57), Expect = 5.7
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 32  HCY-WTSHLQ-----NERELFEQAAEQHSRLLMMHRIKKLFGFIPGSEDVKHIRIPSCQD 85
           HC+ W   L+     + ++L   A  Q +RLLM  R K+  G +   E  + I+  +C D
Sbjct: 447 HCFEWDRKLELDIPDDAKDLIRTAVGQ-TRLLMKERFKQFEGLVDDCEYKRGIKETTCTD 505


>gi|15082228 keratin associated protein 4-2 [Homo sapiens]
          Length = 136

 Score = 26.2 bits (56), Expect = 7.4
 Identities = 9/17 (52%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCCV+ CC P  S   C
Sbjct: 119 SCCVSTCCRPTCSSGSC 135


>gi|60593036 keratin associated protein 5-3 [Homo sapiens]
          Length = 238

 Score = 26.2 bits (56), Expect = 7.4
 Identities = 8/17 (47%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC + CC P +S   C
Sbjct: 212 SCCQSSCCKPCSSQSSC 228


>gi|154146260 keratin associated protein 4-3 [Homo sapiens]
          Length = 195

 Score = 26.2 bits (56), Expect = 7.4
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17 SCCVAKCCSPLTSLQHC 33
          SCC++ CC P   +  C
Sbjct: 43 SCCISSCCRPSCCISSC 59



 Score = 26.2 bits (56), Expect = 7.4
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17 SCCVAKCCSPLTSLQHC 33
          SCC++ CC P   +  C
Sbjct: 73 SCCISSCCRPSCCISSC 89



 Score = 26.2 bits (56), Expect = 7.4
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC++ CC P   +  C
Sbjct: 103 SCCISSCCRPSCCISSC 119



 Score = 26.2 bits (56), Expect = 7.4
 Identities = 8/18 (44%), Positives = 9/18 (50%)

Query: 17  SCCVAKCCSPLTSLQHCY 34
           SCC   CC P   +  CY
Sbjct: 123 SCCQTTCCRPSCCISSCY 140


>gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]
          Length = 854

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 23/107 (21%), Positives = 41/107 (38%), Gaps = 10/107 (9%)

Query: 22  KCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMHRIKKLFGFIPG---------- 71
           K CS    L    W + L+  R L +    Q +R  +    ++    + G          
Sbjct: 678 KLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLH 737

Query: 72  SEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEE 118
           SED +   +   ++WK   +P+L C G + +     L   + E  E+
Sbjct: 738 SEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCED 784


>gi|239758034 PREDICTED: keratin associated protein 4-8 isoform 3
          [Homo sapiens]
          Length = 204

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17 SCCVAKCCSPLTSLQHC 33
          SCC++ CC P   +  C
Sbjct: 77 SCCISSCCRPSCCVSSC 93


>gi|239758032 PREDICTED: keratin associated protein 4-8 isoform 2
          [Homo sapiens]
          Length = 193

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17 SCCVAKCCSPLTSLQHC 33
          SCC++ CC P   +  C
Sbjct: 66 SCCISSCCRPSCCVSSC 82


>gi|239758030 PREDICTED: keratin associated protein 4-8 isoform 1
           [Homo sapiens]
          Length = 220

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC++ CC P   +  C
Sbjct: 93  SCCISSCCRPSCCVSSC 109


>gi|239756798 PREDICTED: similar to keratin associated protein
          4-12 isoform 3 [Homo sapiens]
          Length = 204

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17 SCCVAKCCSPLTSLQHC 33
          SCC++ CC P   +  C
Sbjct: 77 SCCISSCCRPSCCVSSC 93


>gi|239756796 PREDICTED: similar to keratin associated protein
          4-12 isoform 2 [Homo sapiens]
          Length = 193

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17 SCCVAKCCSPLTSLQHC 33
          SCC++ CC P   +  C
Sbjct: 66 SCCISSCCRPSCCVSSC 82


>gi|239756794 PREDICTED: similar to keratin associated protein 4-12
           isoform 1 [Homo sapiens]
          Length = 220

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC++ CC P   +  C
Sbjct: 93  SCCISSCCRPSCCVSSC 109


>gi|239751306 PREDICTED: keratin associated protein 4-8 [Homo
           sapiens]
          Length = 195

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC++ CC P   +  C
Sbjct: 103 SCCISSCCRPSCCVSSC 119


>gi|239745805 PREDICTED: keratin associated protein 4.8 [Homo
           sapiens]
          Length = 185

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC++ CC P   +  C
Sbjct: 93  SCCISSCCRPSCCVSSC 109


>gi|225690554 keratin associated protein 4.8 [Homo sapiens]
          Length = 185

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 7/17 (41%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC++ CC P   +  C
Sbjct: 93  SCCISSCCRPSCCVSSC 109


>gi|4826948 protein kinase, X-linked [Homo sapiens]
          Length = 358

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 55  RLLMMHRIKKLFGFIPGSEDVKHIRIPSCQDWKDI 89
           +LL++ R ++L     G+ DVKH R     DW+ +
Sbjct: 277 KLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAV 311


>gi|60279697 keratin associated protein 5-7 [Homo sapiens]
          Length = 165

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 8/17 (47%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC + CC+P  S   C
Sbjct: 139 SCCQSSCCNPCCSQSSC 155


>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
          Length = 169

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 8/17 (47%), Positives = 9/17 (52%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC + CC P  S   C
Sbjct: 143 SCCQSSCCKPCCSQSRC 159


>gi|60593038 keratin associated protein 5-4 [Homo sapiens]
          Length = 288

 Score = 25.8 bits (55), Expect = 9.7
 Identities = 8/17 (47%), Positives = 10/17 (58%)

Query: 17  SCCVAKCCSPLTSLQHC 33
           SCC + CC+P  S   C
Sbjct: 262 SCCQSSCCNPCCSQSSC 278


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,131,316
Number of Sequences: 37866
Number of extensions: 209308
Number of successful extensions: 1216
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1015
Number of HSP's gapped (non-prelim): 205
length of query: 128
length of database: 18,247,518
effective HSP length: 90
effective length of query: 38
effective length of database: 14,839,578
effective search space: 563903964
effective search space used: 563903964
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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