Search of human proteins with 228008410

Search of human proteins with 228008410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|228008410 BEN domain containing 4 isoform b [Homo sapiens]
         (441 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|228008410 BEN domain containing 4 isoform b [Homo sapiens]         894   0.0  
gi|148762950 BEN domain containing 4 isoform a [Homo sapiens]         890   0.0  
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     50   5e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              49   9e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   1e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    48   2e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    48   2e-05
gi|118572603 ubinuclein 1 [Homo sapiens]                               47   3e-05
gi|118572601 ubinuclein 1 [Homo sapiens]                               47   3e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          47   3e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          47   3e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             47   3e-05
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  46   6e-05
gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]       46   6e-05
gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]       46   8e-05
gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]        46   8e-05
gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]       46   8e-05
gi|119395716 forkhead box C1 [Homo sapiens]                            46   8e-05
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         46   8e-05
gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ...    45   1e-04
gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ...    45   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   1e-04
gi|4503519 eukaryotic translation initiation factor 3, subunit 5...    45   1e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    45   1e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    45   1e-04
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    45   1e-04
gi|112421108 capicua homolog [Homo sapiens]                            45   1e-04
gi|13699803 WAS protein family, member 3 [Homo sapiens]                45   1e-04
gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo ...    45   1e-04
gi|18959210 WIRE protein [Homo sapiens]                                45   1e-04

>gi|228008410 BEN domain containing 4 isoform b [Homo sapiens]
          Length = 441

 Score =  894 bits (2311), Expect = 0.0
 Identities = 441/441 (100%), Positives = 441/441 (100%)

Query: 1   MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPP 60
           MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPP
Sbjct: 1   MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPP 60

Query: 61  PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPP 120
           PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPP
Sbjct: 61  PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPP 120

Query: 121 PASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLS 180
           PASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLS
Sbjct: 121 PASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLS 180

Query: 181 LLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQ 240
           LLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQ
Sbjct: 181 LLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQ 240

Query: 241 QTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE 300
           QTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE
Sbjct: 241 QTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE 300

Query: 301 SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDY 360
           SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDY
Sbjct: 301 SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDY 360

Query: 361 LKMVLQHHNQLLIPQPADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIR 420
           LKMVLQHHNQLLIPQPADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIR
Sbjct: 361 LKMVLQHHNQLLIPQPADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIR 420

Query: 421 FVFTTDELKYSCGLGKRKRIH 441
           FVFTTDELKYSCGLGKRKRIH
Sbjct: 421 FVFTTDELKYSCGLGKRKRIH 441


>gi|148762950 BEN domain containing 4 isoform a [Homo sapiens]
          Length = 534

 Score =  890 bits (2299), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPP 60
           MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPP
Sbjct: 1   MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPP 60

Query: 61  PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPP 120
           PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPP
Sbjct: 61  PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPP 120

Query: 121 PASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLS 180
           PASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLS
Sbjct: 121 PASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLS 180

Query: 181 LLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQ 240
           LLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQ
Sbjct: 181 LLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQ 240

Query: 241 QTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE 300
           QTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE
Sbjct: 241 QTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE 300

Query: 301 SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDY 360
           SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDY
Sbjct: 301 SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDY 360

Query: 361 LKMVLQHHNQLLIPQPADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIR 420
           LKMVLQHHNQLLIPQPADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIR
Sbjct: 361 LKMVLQHHNQLLIPQPADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIR 420

Query: 421 FVFTTDELKYSCGLGKRKR 439
           FVFTTDELKYSCGLGKRKR
Sbjct: 421 FVFTTDELKYSCGLGKRKR 439


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 8/114 (7%)

Query: 41  YERPTLVELPHVRAPPPPPP------PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAA 94
           Y     V+ P   A PP PP      P A  AA    +  PPP      ++ P    RAA
Sbjct: 93  YRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAA 152

Query: 95  AAASSSSPSCTPATS--QGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAA 146
           AAA+++ PS  PA    +     P   PP +PAA  + +  A  R  P  A AA
Sbjct: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA 206



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 42/157 (26%), Positives = 54/157 (34%), Gaps = 41/157 (26%)

Query: 50  PHVRAPPPPPPPFA-------PHAAVSISSSEPPP---------QQFQAQSSYPPGPGRA 93
           P   APPPPP P A       P AA + +++ P P         Q+    ++ PP P   
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAP 187

Query: 94  AAAASSSSPSCTPATSQGHLRTPAQPPPASPA-------------------------ASS 128
            A A  + P   P  +      P  PPP  PA                         A+ 
Sbjct: 188 PAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAAR 247

Query: 129 SSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESR 165
             S   VVRY  G+  A G    G     LE  A +R
Sbjct: 248 PVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAAR 284



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 11/96 (11%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHA 66
           PA+ GP   +     +P       P+  P    R   P  V       PPPP PP  P  
Sbjct: 164 PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP-- 221

Query: 67  AVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSP 102
                  +PPP Q Q     PP  G A  A  ++ P
Sbjct: 222 ----QQQQPPPPQPQ-----PPPEGGAVRAGGAARP 248



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 69  SISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASS 128
           SIS       Q   + + PP P RA   A +++ +  P        TPA PPP +P A++
Sbjct: 90  SISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPP------TPAPPPPPAPVAAA 143

Query: 129 SSSFAAVVRYGPGAAAAAGT 148
           + + A      P AAAAA T
Sbjct: 144 APARA------PRAAAAAAT 157


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 13/143 (9%)

Query: 12  PSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSIS 71
           PS P  Y    P +       + P+ ++  E P    L     PPPPPP  AP       
Sbjct: 731 PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEP----LQDPNWPPPPPP--APEEQDLSM 784

Query: 72  SSEPPPQQ--FQAQSSYPPGPGRA-----AAAASSSSPSCTPATSQGHLRTPAQPPPASP 124
           +  PPP++  F   S  P GP  +     + AASSSS +       G    P  PP  +P
Sbjct: 785 ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844

Query: 125 AASSSSSFAAVVRYGPGAAAAAG 147
           A+S+    A + +  P   +  G
Sbjct: 845 ASSAPGHVAKLPQKEPVGCSKGG 867



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 19/140 (13%)

Query: 5   MQPAEEGPSVPKIYKQRSPYSVLKTF-----PSKRPALAKRYERPTLVELPH--VRAP-- 55
           + P +E P + K   Q  P S   ++     P+K+P +    E P+  E     ++ P  
Sbjct: 714 LTPLQESPVISK--DQSPPPSPPPSYHPPPPPTKKPEVV--VEAPSASETAEEPLQDPNW 769

Query: 56  PPPPPPFAPHAAVSISSSEPPPQQ--FQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHL 113
           PPPPPP AP       +  PPP++  F   S  P GP  +    SS + S + AT+   +
Sbjct: 770 PPPPPP-APEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL-QI 827

Query: 114 RTPA--QPPPASPAASSSSS 131
           + P    PPPA PA + +SS
Sbjct: 828 QPPGSPDPPPAPPAPAPASS 847



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 7/118 (5%)

Query: 14  VPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELP------HVRAPPPPPPPFAPHAA 67
           +P   K  +P+S   + P      A     P +V  P        ++PP P     P   
Sbjct: 660 IPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQE 719

Query: 68  VSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPA 125
             + S +  P      S +PP P          +PS +  T++  L+ P  PPP  PA
Sbjct: 720 SPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS-ETAEEPLQDPNWPPPPPPA 776



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 16/99 (16%)

Query: 47  VELPHVRAPPPPPPPFAPHAAVSISSSEP---------PPQQFQAQSSYPPGPGRAAAAA 97
           V L  ++ PPPPP     H+      + P         P ++ Q Q   PP  G +  A 
Sbjct: 489 VSLRKLKRPPPPPR--RTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAG 546

Query: 98  SSSSP-----SCTPATSQGHLRTPAQPPPASPAASSSSS 131
           ++  P     S  P  S G  R P + P  + + SS  S
Sbjct: 547 AAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS 585


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 44/132 (33%), Positives = 50/132 (37%), Gaps = 33/132 (25%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRA-----AAAASSSSPSC 104
           P  + PPP  PP  PH         PPP Q  ++     GPG A     A  ASSS+P  
Sbjct: 77  PPPQQPPPHQPP--PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPA 134

Query: 105 TPATS-----QGHLRTPAQP------PPASPAASSSSSF---------------AAVVRY 138
           TP TS      G   TP  P      PP +P  +  SS                AAV   
Sbjct: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194

Query: 139 GPGAAAAAGTGG 150
           GPG     G GG
Sbjct: 195 GPGPKQGPGPGG 206


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 44/137 (32%), Positives = 63/137 (45%), Gaps = 12/137 (8%)

Query: 25  SVLKTFPSKRPALAKRYERPTLVELPH---VRAPPPPP---PPFAPHAAVSISSSEPPPQ 78
           S++   P+    L K     T+++ P      APP P    PP AP A  + +++ PPP 
Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAP-APAAPAAAPPPPP 274

Query: 79  QFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRY 138
              A  + PPG       A+ + P   PA +Q      A P PA PAA   +  +   + 
Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVP--PPAAAQNGGSAGAAPAPA-PAAGGPAGVSG--QP 329

Query: 139 GPGAAAAAGTGGTGSDS 155
           GPGAAAAA   G  ++S
Sbjct: 330 GPGAAAAAPAPGVKAES 346



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 13/111 (11%)

Query: 57  PPPPPFAPHAAVS----ISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGH 112
           P P P AP   +     + ++ PP     A  S P  P  AA AA+   P   PAT    
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAAPPAP---AAPSPPAAPAPAAPAAAPPPPPPAPATLARP 283

Query: 113 LRTPAQPPPASP------AASSSSSFAAVVRYGPGAAAAAGTGGTGSDSAS 157
              PA PP A+P      AA +  S  A     P A   AG  G     A+
Sbjct: 284 PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 50/166 (30%), Positives = 62/166 (37%), Gaps = 17/166 (10%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHA 66
           PA   PS P      +P +     P   PA A     P     P   AP  PPP  A + 
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAP---PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306

Query: 67  AVSISSSEPPPQQF-QAQSSYPPGPGRAAAA----ASSSSPSCTPATSQGHLRTPAQPPP 121
             + ++  P P     A  S  PGPG AAAA      + SP      +    +T A   P
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGP 366

Query: 122 ASPAAS---------SSSSFAAVVRYGPGAAAAAGTGGTGSDSASL 158
           AS AAS         +  S AAV    PG       G  G+ + SL
Sbjct: 367 ASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSL 412



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 29/100 (29%), Positives = 37/100 (37%), Gaps = 8/100 (8%)

Query: 54  APPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAA----SSSSPSCTPATS 109
           AP PPP   A           PP  +   +   P GP   AA        S+ SC P  +
Sbjct: 86  APEPPPAGRARPGGGGPQRPGPPSPR---RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142

Query: 110 QGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTG 149
              +    +P PA PA  +  + A   R GPG     G G
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPA-ALAARAGPGPGPGPGPG 181


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 11/83 (13%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
           P    PPPPPPP  PH      +S PPP   + + + PP P RA  AA    P   P+ +
Sbjct: 282 PSRGGPPPPPPP--PH------NSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVA 333

Query: 110 ---QGHLRTPAQPPPASPAASSS 129
                  R    PPPA P+++ S
Sbjct: 334 VPPPPPNRMYPPPPPALPSSAPS 356



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 30/79 (37%), Positives = 35/79 (44%), Gaps = 13/79 (16%)

Query: 50  PHVRAP---PPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTP 106
           P  RAP   PPPPPP  P  AV      PPP +      YPP P    ++A S  P   P
Sbjct: 313 PPSRAPTAAPPPPPPSRPSVAVP----PPPPNRM-----YPPPPPALPSSAPSGPPPPPP 363

Query: 107 AT-SQGHLRTPAQPPPASP 124
           +    G +  P  PPP  P
Sbjct: 364 SVLGVGPVAPPPPPPPPPP 382



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/117 (25%), Positives = 38/117 (32%), Gaps = 13/117 (11%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPP------P 60
           P   GP  P    + +P       PS+ P  A     P+    P V  PPPPP      P
Sbjct: 294 PHNSGPPPPPARGRGAPPPP----PSRAPTAAPPPPPPSR---PSVAVPPPPPNRMYPPP 346

Query: 61  PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPA 117
           P A  ++       PPP         PP P           P   P+     + T A
Sbjct: 347 PPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTA 403



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 18/97 (18%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYER------PTLVELPHVRAPPPPPP 60
           P    PS P +     P +  + +P   PAL            P+++ +  V  PPPPPP
Sbjct: 322 PPPPPPSRPSVAVPPPPPN--RMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379

Query: 61  PFAPHAAVSISSSEPPPQQFQAQSSY--PPGPGRAAA 95
           P  P          PPP    +   +  P   G  AA
Sbjct: 380 PPPP--------GPPPPPGLPSDGDHQVPTTAGNKAA 408


>gi|118572603 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 48/184 (26%), Positives = 71/184 (38%), Gaps = 36/184 (19%)

Query: 3   EEMQPAEEGPSVPKIYKQRSPYSVL-KTFPSKRPALAKRYERPTLVELPHVRAPPPPPPP 61
           +E +P   G      YK+ S  + L K  P    + AK +  P     P V  P P P  
Sbjct: 751 QEKKPESSG------YKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVPVPGPQV 804

Query: 62  FAPHAAVSISSSEPPPQQF--------------------------QAQSSYPPGPGRAAA 95
              HA      +  PP  F                          + Q  +P  P  +  
Sbjct: 805 KVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGG 864

Query: 96  -AASSSSPSCTPATSQGHLRTPAQPPPASPAASS--SSSFAAVVRYGPGAAAAAGTGGTG 152
            +ASSSS   TPA+S   L  PA+P   S A SS  ++ FA+ +     ++ ++ +GGT 
Sbjct: 865 LSASSSSSHKTPASSSSALSHPAKPHSVSSAGSSYKNNPFASSISKHGVSSGSSSSGGTP 924

Query: 153 SDSA 156
             S+
Sbjct: 925 VQSS 928


>gi|118572601 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 48/184 (26%), Positives = 71/184 (38%), Gaps = 36/184 (19%)

Query: 3   EEMQPAEEGPSVPKIYKQRSPYSVL-KTFPSKRPALAKRYERPTLVELPHVRAPPPPPPP 61
           +E +P   G      YK+ S  + L K  P    + AK +  P     P V  P P P  
Sbjct: 751 QEKKPESSG------YKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVPVPGPQV 804

Query: 62  FAPHAAVSISSSEPPPQQF--------------------------QAQSSYPPGPGRAAA 95
              HA      +  PP  F                          + Q  +P  P  +  
Sbjct: 805 KVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGG 864

Query: 96  -AASSSSPSCTPATSQGHLRTPAQPPPASPAASS--SSSFAAVVRYGPGAAAAAGTGGTG 152
            +ASSSS   TPA+S   L  PA+P   S A SS  ++ FA+ +     ++ ++ +GGT 
Sbjct: 865 LSASSSSSHKTPASSSSALSHPAKPHSVSSAGSSYKNNPFASSISKHGVSSGSSSSGGTP 924

Query: 153 SDSA 156
             S+
Sbjct: 925 VQSS 928


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 49/174 (28%), Positives = 69/174 (39%), Gaps = 27/174 (15%)

Query: 3   EEMQPAEEGPSVPKIYK--------QRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRA 54
           E ++P+   PS P I +        Q+  +   +  P+K PA      +P L + P    
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP-LAQQPGTVK 350

Query: 55  PPPPPPPFAPHAAVSISSSEPPPQQFQAQ--SSYPPGPGRAAAAASSSSPSCTPATSQGH 112
           PP  PP      A  +  ++PP QQ  ++  SS  PGP    A A       TPA   G 
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP---KALAQPPGVGKTPAQQPGP 407

Query: 113 LRTPA-----------QPPPASPAASSSSSFAAVVRYGPG--AAAAAGTGGTGS 153
            + P            QP   SPA +   +   V + GPG   A  AG G T +
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 43/133 (32%), Positives = 54/133 (40%), Gaps = 37/133 (27%)

Query: 25  SVLKTFPSKRPALAKRYERPTLVELPHVRAPPP------PPPPFAPHAAVSIS----SSE 74
           S  +T P+K P+           +LP    PPP       PPP  P +A   S    S++
Sbjct: 460 SAQQTGPTKPPS-----------QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK 508

Query: 75  PPPQQ--------FQAQSSYPPG--PGRAAAAASSSSPS------CTPATSQGHLRTPAQ 118
           PPPQQ         Q  S+ PP   PG A  +A   SP+       T   SQ     P Q
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568

Query: 119 PPPASPAASSSSS 131
           PP  SP+A    S
Sbjct: 569 PPTVSPSAKQPPS 581



 Score = 35.8 bits (81), Expect = 0.080
 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 14/119 (11%)

Query: 6   QPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPH 65
           +P+ E P  PK   Q  P  V KT P+++P  AK   +      P  + P    P  AP 
Sbjct: 380 KPSSEQPG-PKALAQ--PPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP- 434

Query: 66  AAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP 124
                   +P P +  AQ +   GPG+ +A    + P+  P+   G    PA+PPP  P
Sbjct: 435 GPTKTPVQQPGPGKIPAQQA---GPGKTSA--QQTGPTKPPSQLPG----PAKPPPQQP 484



 Score = 32.3 bits (72), Expect = 0.88
 Identities = 25/82 (30%), Positives = 30/82 (36%), Gaps = 7/82 (8%)

Query: 49  LPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPAT 108
           LP    PP      + H    + SS PP Q     S  PP PGR A    S S   T  T
Sbjct: 66  LPKGSVPPAAAESPSMHRKQELDSSHPPKQ-----SGRPPDPGRPAQPGLSKSR--TTDT 118

Query: 109 SQGHLRTPAQPPPASPAASSSS 130
            +   + P + P       S S
Sbjct: 119 FRSEQKLPGRSPSTISLKESKS 140



 Score = 32.3 bits (72), Expect = 0.88
 Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 12/86 (13%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRA--------AAAASSSS 101
            PH ++ P  P   AP  +   +S  PP    QA    PP P ++        A AA    
Sbjct: 954  PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA----PPAPAKSIPVKKETKAPAAEKLE 1009

Query: 102  PSCTPATSQGHLRTPAQPPPASPAAS 127
            P    A +     T  +PPP   + S
Sbjct: 1010 PKAEQAPTVKRTETEKKPPPIKDSKS 1035



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 9/87 (10%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
            P V + P  P PF   +++ IS+  PPP         PP P           P   P TS
Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPP--------PPPPPPPPPPPPPPPPPLPPPTS 2432

Query: 110  QGHLRTPAQP-PPASPAASSSSSFAAV 135
                  P +    ASP  +++  F AV
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAV 2459



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 26/141 (18%)

Query: 7   PAEE-GPSVPKIYKQRSPYSVLKT----FPSKRPALAKR-YERPTLVELPHVRAPP---- 56
           PA++ GP+ P   +  +P  + +      P+K P   K   ++P   ++P  +A P    
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460

Query: 57  ------PPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQ 110
                   PP   P  A      +PPPQQ       P  PG A   +     +  P    
Sbjct: 461 AQQTGPTKPPSQLPGPA------KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514

Query: 111 GHLRTPAQPPPASPAASSSSS 131
           G    PA+P P  P ++   S
Sbjct: 515 G----PAKPSPQQPGSTKPPS 531



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 12/112 (10%)

Query: 32   SKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPG 91
            S  PA  + + R + +++     PPPPPPP  P           PP      +  P    
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKL 2443

Query: 92   RAAAAASSSSP---SCTPATSQGHLRT---------PAQPPPASPAASSSSS 131
              A+  ++++P   + T   +   LR+            PPP  P  SS  S
Sbjct: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 18/108 (16%)

Query: 39   KRYERPTLVEL---PHVRAPPP----PPPPFAPHAAVSISSSEPPPQQFQAQSSYPP--- 88
            K  +RPT +E+    H+RA       P PP +P    S  S   P +  +  S++ P   
Sbjct: 3588 KDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALE--SAFVPYEK 3645

Query: 89   ------GPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSS 130
                   P +      +  P  +P T++   R+ + P P SP A  SS
Sbjct: 3646 PLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESS 3693



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 31/132 (23%), Positives = 49/132 (37%), Gaps = 16/132 (12%)

Query: 12  PSVPKIYKQRSPYS----VLKTFPSKRPALAKRYERPT--LVELPHVRAPPPPPPPFAPH 65
           PS P+   + +P +    V K+ P  +    K+   P   L + P  + PPP       H
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713

Query: 66  AAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPA 125
            + S  + +PP    +A S   P P +  +  S    +  P         P QP    P 
Sbjct: 714 GSPSAKAKQPP----EADSLSKPAPPKEPSVPSEQDKA--PVADD----KPKQPKMVKPT 763

Query: 126 ASSSSSFAAVVR 137
               SS +A  +
Sbjct: 764 TDLVSSSSATTK 775


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 49/174 (28%), Positives = 69/174 (39%), Gaps = 27/174 (15%)

Query: 3   EEMQPAEEGPSVPKIYK--------QRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRA 54
           E ++P+   PS P I +        Q+  +   +  P+K PA      +P L + P    
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP-LAQQPGTVK 350

Query: 55  PPPPPPPFAPHAAVSISSSEPPPQQFQAQ--SSYPPGPGRAAAAASSSSPSCTPATSQGH 112
           PP  PP      A  +  ++PP QQ  ++  SS  PGP    A A       TPA   G 
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP---KALAQPPGVGKTPAQQPGP 407

Query: 113 LRTPA-----------QPPPASPAASSSSSFAAVVRYGPG--AAAAAGTGGTGS 153
            + P            QP   SPA +   +   V + GPG   A  AG G T +
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 43/133 (32%), Positives = 54/133 (40%), Gaps = 37/133 (27%)

Query: 25  SVLKTFPSKRPALAKRYERPTLVELPHVRAPPP------PPPPFAPHAAVSIS----SSE 74
           S  +T P+K P+           +LP    PPP       PPP  P +A   S    S++
Sbjct: 460 SAQQTGPTKPPS-----------QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK 508

Query: 75  PPPQQ--------FQAQSSYPPG--PGRAAAAASSSSPS------CTPATSQGHLRTPAQ 118
           PPPQQ         Q  S+ PP   PG A  +A   SP+       T   SQ     P Q
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568

Query: 119 PPPASPAASSSSS 131
           PP  SP+A    S
Sbjct: 569 PPTVSPSAKQPPS 581



 Score = 35.8 bits (81), Expect = 0.080
 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 14/119 (11%)

Query: 6   QPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPH 65
           +P+ E P  PK   Q  P  V KT P+++P  AK   +      P  + P    P  AP 
Sbjct: 380 KPSSEQPG-PKALAQ--PPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP- 434

Query: 66  AAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP 124
                   +P P +  AQ +   GPG+ +A    + P+  P+   G    PA+PPP  P
Sbjct: 435 GPTKTPVQQPGPGKIPAQQA---GPGKTSA--QQTGPTKPPSQLPG----PAKPPPQQP 484



 Score = 32.3 bits (72), Expect = 0.88
 Identities = 25/82 (30%), Positives = 30/82 (36%), Gaps = 7/82 (8%)

Query: 49  LPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPAT 108
           LP    PP      + H    + SS PP Q     S  PP PGR A    S S   T  T
Sbjct: 66  LPKGSVPPAAAESPSMHRKQELDSSHPPKQ-----SGRPPDPGRPAQPGLSKSR--TTDT 118

Query: 109 SQGHLRTPAQPPPASPAASSSS 130
            +   + P + P       S S
Sbjct: 119 FRSEQKLPGRSPSTISLKESKS 140



 Score = 32.3 bits (72), Expect = 0.88
 Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 12/86 (13%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRA--------AAAASSSS 101
            PH ++ P  P   AP  +   +S  PP    QA    PP P ++        A AA    
Sbjct: 954  PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA----PPAPAKSIPVKKETKAPAAEKLE 1009

Query: 102  PSCTPATSQGHLRTPAQPPPASPAAS 127
            P    A +     T  +PPP   + S
Sbjct: 1010 PKAEQAPTVKRTETEKKPPPIKDSKS 1035



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 9/87 (10%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
            P V + P  P PF   +++ IS+  PPP         PP P           P   P TS
Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPP--------PPPPPPPPPPPPPPPPPLPPPTS 2432

Query: 110  QGHLRTPAQP-PPASPAASSSSSFAAV 135
                  P +    ASP  +++  F AV
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAV 2459



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 26/141 (18%)

Query: 7   PAEE-GPSVPKIYKQRSPYSVLKT----FPSKRPALAKR-YERPTLVELPHVRAPP---- 56
           PA++ GP+ P   +  +P  + +      P+K P   K   ++P   ++P  +A P    
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460

Query: 57  ------PPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQ 110
                   PP   P  A      +PPPQQ       P  PG A   +     +  P    
Sbjct: 461 AQQTGPTKPPSQLPGPA------KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514

Query: 111 GHLRTPAQPPPASPAASSSSS 131
           G    PA+P P  P ++   S
Sbjct: 515 G----PAKPSPQQPGSTKPPS 531



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 12/112 (10%)

Query: 32   SKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPG 91
            S  PA  + + R + +++     PPPPPPP  P           PP      +  P    
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKL 2443

Query: 92   RAAAAASSSSP---SCTPATSQGHLRT---------PAQPPPASPAASSSSS 131
              A+  ++++P   + T   +   LR+            PPP  P  SS  S
Sbjct: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 18/108 (16%)

Query: 39   KRYERPTLVEL---PHVRAPPP----PPPPFAPHAAVSISSSEPPPQQFQAQSSYPP--- 88
            K  +RPT +E+    H+RA       P PP +P    S  S   P +  +  S++ P   
Sbjct: 3588 KDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALE--SAFVPYEK 3645

Query: 89   ------GPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSS 130
                   P +      +  P  +P T++   R+ + P P SP A  SS
Sbjct: 3646 PLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESS 3693



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 31/132 (23%), Positives = 49/132 (37%), Gaps = 16/132 (12%)

Query: 12  PSVPKIYKQRSPYS----VLKTFPSKRPALAKRYERPT--LVELPHVRAPPPPPPPFAPH 65
           PS P+   + +P +    V K+ P  +    K+   P   L + P  + PPP       H
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713

Query: 66  AAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPA 125
            + S  + +PP    +A S   P P +  +  S    +  P         P QP    P 
Sbjct: 714 GSPSAKAKQPP----EADSLSKPAPPKEPSVPSEQDKA--PVADD----KPKQPKMVKPT 763

Query: 126 ASSSSSFAAVVR 137
               SS +A  +
Sbjct: 764 TDLVSSSSATTK 775


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 44/154 (28%), Positives = 59/154 (38%), Gaps = 9/154 (5%)

Query: 6    QPAEEGPSVPKIYKQRSPYSVLKT--FPSKRPALAKRYERPTLVELPHVRAPPPPPPPFA 63
            +P     +VP   +  SP + + T   P+   A     E PT        A P P  P +
Sbjct: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT----SPAAAVPTPEEPTS 1093

Query: 64   PHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPAS 123
            P AAV        P    A    P  P   AAA  +     +PA +      PA P PA 
Sbjct: 1094 PAAAVPTPEEPTSPA---AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 124  PAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSAS 157
            P    S+S A  V     +A+ A    T ++SAS
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESAS 1184



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 9/133 (6%)

Query: 6    QPAEEGPSVPKIYKQRSPYSVLKT--FPSKRPALAKRYERPTLVELPHVRAPPPPPPPFA 63
            +P     +VP   +  SP + + T   P+   A     E PT        A P P  P +
Sbjct: 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT----SPAAAVPTPEEPAS 1119

Query: 64   PHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPAS 123
            P AAV        P    A    P  P   A A  +   S + A +       A P  A 
Sbjct: 1120 PAAAVPTPEEPASPA---AAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176

Query: 124  PAASSSSSFAAVV 136
            P  + S+SFAAVV
Sbjct: 1177 PTPAESASFAAVV 1189



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 42/177 (23%), Positives = 68/177 (38%), Gaps = 20/177 (11%)

Query: 6    QPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPF--- 62
            +P     +VP   +  SP + + T P +  + A     P     P    P P  P F   
Sbjct: 1090 EPTSPAAAVPTPEEPTSPAAAVPT-PEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP 1148

Query: 63   ---APHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAAS-------SSSPSC---TPATS 109
                P  + S + + P P++  + ++  P P  +A+ A+        +SP+    TPA  
Sbjct: 1149 AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAM 1208

Query: 110  QGHLRTPAQPPPASPAASSSSSFAAVV---RYGPGAAAAAGTGGTGSDSASLELSAE 163
               L     P  + P +   +S AA V         AAA  T    + SA+  L+ E
Sbjct: 1209 VATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE 1265



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 37/151 (24%), Positives = 49/151 (32%), Gaps = 2/151 (1%)

Query: 7    PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHA 66
            P E   +  ++     P S     P+     +     PT  E     A  PPP      A
Sbjct: 984  PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA 1043

Query: 67   AVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAA 126
            A   +  EP      A    P  P   AAA  +     +PA +      P  P  A P  
Sbjct: 1044 AAVPTPEEPTSP--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1101

Query: 127  SSSSSFAAVVRYGPGAAAAAGTGGTGSDSAS 157
               +S AA V      A+ A    T  + AS
Sbjct: 1102 EEPTSPAAAVPTPEEPASPAAAVPTPEEPAS 1132



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 37/133 (27%), Positives = 47/133 (35%), Gaps = 5/133 (3%)

Query: 7    PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRY---ERPTLVELPHVRAPPPPPPPFA 63
            P E  P+V     Q    S +  F  +  ALA      E     E P   A     P   
Sbjct: 929  PEETAPAVAAAITQEG-MSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987

Query: 64   PHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPAS 123
              AAV +S+ E P     A  + P  P   AAA  +     +PA +      P  P  A 
Sbjct: 988  DTAAVRVSTPEEPASPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAV 1046

Query: 124  PAASSSSSFAAVV 136
            P     +S AA V
Sbjct: 1047 PTPEEPTSPAAAV 1059


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 31/168 (18%)

Query: 14   VPKIYKQRSPYSVLKTFPSK-RPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSI-- 70
            VPK+    +P S     P    P + + +  P  V      +P PPPPP AP    ++  
Sbjct: 1236 VPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPV------SPKPPPPPTAPKPVKAVAG 1289

Query: 71   --------SSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPA 122
                    S +  P +Q  A  + PPG   +  A    SP+  P+     L  PA+PP A
Sbjct: 1290 LPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGA----SPAKPPSPGAPALHVPAKPPRA 1345

Query: 123  SPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDA 170
            + AA+++++          A  A   G +  DSA  +L   S  +  A
Sbjct: 1346 AAAAAAAAA----------APPAPPEGASPGDSARQKLEETSACLAAA 1383



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 29/118 (24%), Positives = 42/118 (35%), Gaps = 2/118 (1%)

Query: 11   GPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSI 70
            GP  P++ +       +   P   P   K  +   +  LP   A P P P  A     ++
Sbjct: 1254 GPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVK--AVAGLPSGSAGPSPAPSPARQPPAAL 1311

Query: 71   SSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASS 128
            +     P    A  + PP PG  A    +  P    A +      PA P  ASP  S+
Sbjct: 1312 AKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSA 1369



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 29/109 (26%), Positives = 36/109 (33%), Gaps = 22/109 (20%)

Query: 43   RPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSP 102
            RP   +      PPPPPP            +EPPP         PP  G A        P
Sbjct: 1180 RPASEQAGPPELPPPPPP------------AEPPPTDLAHLPPLPPPEGEA------RKP 1221

Query: 103  SCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGGT 151
            +  P + +  L  P      SP  +S      V   GPG+       GT
Sbjct: 1222 AKPPVSPKPVLTQPVPKLQGSPTPTSKK----VPLPGPGSPEVKRAHGT 1266



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 28/126 (22%), Positives = 46/126 (36%), Gaps = 24/126 (19%)

Query: 20  QRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISS------- 72
           Q++ Y+  +  P +R A       P  +E+  + +PPPP P  A   +  +++       
Sbjct: 606 QKAEYAKYEGGPLRRKA-------PQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELS 658

Query: 73  ----------SEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPA 122
                     +E  P   +  S  PP P       SS        +S   L     P P+
Sbjct: 659 DELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPS 718

Query: 123 SPAASS 128
           SP + S
Sbjct: 719 SPMSRS 724



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 19/67 (28%), Positives = 24/67 (35%), Gaps = 3/67 (4%)

Query: 55   PPPPPPPFAPHAAVSISSSEPPPQQF-QAQSSYPPGPGRAAAAASSSSPSCTPATSQGHL 113
            P PPPP    H         P  +Q    +   PP P        +  P   P   +G  
Sbjct: 1161 PEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPP--PEGEA 1218

Query: 114  RTPAQPP 120
            R PA+PP
Sbjct: 1219 RKPAKPP 1225


>gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]
          Length = 667

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 49/177 (27%), Positives = 63/177 (35%), Gaps = 22/177 (12%)

Query: 19  KQRSPYSVLKTFPSKRPALAKRYERPTLVELP-------HVRAPPPPPPPFAPHAAVSIS 71
           +Q  P   L   P   P      + P  + LP          APP P PP      +S S
Sbjct: 475 QQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSS 534

Query: 72  SSEPPPQQFQAQSSYPPGPGRAAAA-ASSSSPSCTPATSQGHLRTPAQPPPASPAASSSS 130
           SS P  QQ  + S+  PG G    +  +++ PS  P        T A PP  +P+   S 
Sbjct: 535 SSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTA-PPSTAPSGPGSV 593

Query: 131 SFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLSLLNCGGK 187
               VV   P      G GG  S  + +   A S   L   A           CGGK
Sbjct: 594 QKYIVVSLPP---TGEGKGGPTSHPSPVPPPASSPSPLSGSAL----------CGGK 637


>gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]
          Length = 667

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 49/176 (27%), Positives = 62/176 (35%), Gaps = 22/176 (12%)

Query: 20  QRSPYSVLKTFPSKRPALAKRYERPTLVELP-------HVRAPPPPPPPFAPHAAVSISS 72
           Q  P   L   P   P      + P  + LP          APP P PP      +S SS
Sbjct: 476 QPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSS 535

Query: 73  SEPPPQQFQAQSSYPPGPGRAAAA-ASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSS 131
           S P  QQ  + S+  PG G    +  +++ PS  P        T A PP  +P+   S  
Sbjct: 536 SAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTA-PPSTAPSGPGSVQ 594

Query: 132 FAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLSLLNCGGK 187
              VV   P      G GG  S  + +   A S   L   A           CGGK
Sbjct: 595 KYIVVSLPP---TGEGKGGPTSHPSPVPPPASSPSPLSGSAL----------CGGK 637


>gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]
          Length = 677

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 49/176 (27%), Positives = 62/176 (35%), Gaps = 22/176 (12%)

Query: 20  QRSPYSVLKTFPSKRPALAKRYERPTLVELP-------HVRAPPPPPPPFAPHAAVSISS 72
           Q  P   L   P   P      + P  + LP          APP P PP      +S SS
Sbjct: 486 QPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSS 545

Query: 73  SEPPPQQFQAQSSYPPGPGRAAAA-ASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSS 131
           S P  QQ  + S+  PG G    +  +++ PS  P        T A PP  +P+   S  
Sbjct: 546 SAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTA-PPSTAPSGPGSVQ 604

Query: 132 FAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLSLLNCGGK 187
              VV   P      G GG  S  + +   A S   L   A           CGGK
Sbjct: 605 KYIVVSLPP---TGEGKGGPTSHPSPVPPPASSPSPLSGSAL----------CGGK 647


>gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]
          Length = 677

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 49/176 (27%), Positives = 62/176 (35%), Gaps = 22/176 (12%)

Query: 20  QRSPYSVLKTFPSKRPALAKRYERPTLVELP-------HVRAPPPPPPPFAPHAAVSISS 72
           Q  P   L   P   P      + P  + LP          APP P PP      +S SS
Sbjct: 486 QPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSS 545

Query: 73  SEPPPQQFQAQSSYPPGPGRAAAA-ASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSS 131
           S P  QQ  + S+  PG G    +  +++ PS  P        T A PP  +P+   S  
Sbjct: 546 SAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTA-PPSTAPSGPGSVQ 604

Query: 132 FAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQCSRVLSLLNCGGK 187
              VV   P      G GG  S  + +   A S   L   A           CGGK
Sbjct: 605 KYIVVSLPP---TGEGKGGPTSHPSPVPPPASSPSPLSGSAL----------CGGK 647


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 47/153 (30%), Positives = 63/153 (41%), Gaps = 13/153 (8%)

Query: 13  SVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSIS- 71
           +VPKI    S  S L +  S   +L     RP  ++      PPP P    PH +   S 
Sbjct: 253 AVPKIESPDSSSSSLSSGSSPPGSLPSA--RPLSLDGADSAPPPPAPSAPPPHHSQGFSV 310

Query: 72  -----SSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAA 126
                S    PQ   A+ S     G  A+AA+SS     P  + G   +P Q    S   
Sbjct: 311 DNIMTSLRGSPQSAAAELS----SGLLASAAASSRAGIAPPLALGAY-SPGQSSLYSSPC 365

Query: 127 SSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLE 159
           S +SS  +    G GA AA G GG G+   +L+
Sbjct: 366 SQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQ 398



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 50/187 (26%), Positives = 70/187 (37%), Gaps = 35/187 (18%)

Query: 33  KRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEP-PPQQFQAQSSYPPGPG 91
           K P    R   P   E     AP P PPP       + + + P PPQ     ++   G G
Sbjct: 192 KEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAAL--GSG 249

Query: 92  RAAAA-------ASSSS-----------PSCTPATSQGHLRTPAQPPPASPAASSSSSFA 133
            AAA        +SSSS           PS  P +  G    P  P P++P    S  F+
Sbjct: 250 SAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFS 309

Query: 134 -----AVVRYGPGAAAAAGTGGTGSDSAS---------LELSAESRMILDAFAQQCSRVL 179
                  +R  P +AAA  + G  + +A+         L L A S      ++  CS+  
Sbjct: 310 VDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTS 369

Query: 180 SLLNCGG 186
           S  + GG
Sbjct: 370 SAGSSGG 376



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 31/107 (28%)

Query: 33  KRPALAKRYERPTLVELPHVRAPPPP---PPPFAPHAAVSISSSEPPPQQFQAQSSYPPG 89
           K+ A+  + E+  L    H++ PPPP   PPP              PP+Q    +  P  
Sbjct: 176 KKDAVKDKEEKDRL----HLKEPPPPGRQPPP-------------APPEQADGNAPGPQP 218

Query: 90  PGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVV 136
           P        + + +C           P+ P P SPAA+  S  AA V
Sbjct: 219 PPVRIQDIKTENGTC-----------PSPPQPLSPAAALGSGSAAAV 254


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 10/108 (9%)

Query: 57  PPPPPFAPHAAVSI---SSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHL 113
           PPP P   H+   +      +PPP+        P GPG   A      PS   A+     
Sbjct: 550 PPPSPLLNHSLFGVLTGGGGQPPPEPLLPP---PGGPGPPLAPGEPEGPSLLVASLLPPP 606

Query: 114 RTPAQPPPASPAASSSSSFAAVVRYGP----GAAAAAGTGGTGSDSAS 157
            +   PPP++P ++  +SF  ++  GP    G  +A G GG   +  S
Sbjct: 607 PSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFS 654



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 49  LPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSP------ 102
           LP   AP P PP   P  A+S+++           S  P   G   A  +SSSP      
Sbjct: 204 LPRGNAPSPAPP---PPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL 260

Query: 103 -----SCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGP--GAAAAAGTGGTGSDS 155
                + TP         PA P PAS    SS++    +  GP  GA    G G     +
Sbjct: 261 FHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLA 320

Query: 156 ASLELSAESR 165
           +SL LSA ++
Sbjct: 321 SSL-LSAAAK 329



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 37/166 (22%), Positives = 53/166 (31%), Gaps = 28/166 (16%)

Query: 6   QPAEEGPSV-------PKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPP 58
           +P  + PS        P   + R P +V +    + P   +R        +P   + P P
Sbjct: 345 RPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEP 404

Query: 59  PPPFAPHAAVSISSSEPPPQQ-------FQAQSSYPPGPGRAAAAASSSSP--------S 103
             P  P     +    P P           + +  PP P       SS SP         
Sbjct: 405 SQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPP-----TLSSGSPPQPRHPIQP 459

Query: 104 CTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTG 149
             P T+ G L +     PA PAAS +    + V   P      G G
Sbjct: 460 SLPGTTSGSL-SSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAG 504



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 10/88 (11%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSS-------YPPGPGRAAAAASSSSP 102
           P    PP   PP  P      S    PP   QA  +       +PP       +  SSSP
Sbjct: 142 PPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSP 201

Query: 103 SCTPATSQGHLRTPAQPPPASPAASSSS 130
              P   +G+  +PA PPP + + ++ S
Sbjct: 202 RFLP---RGNAPSPAPPPPPAISLNAPS 226


>gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo
           sapiens]
          Length = 493

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/102 (34%), Positives = 45/102 (44%), Gaps = 4/102 (3%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
           P   AP PPP P AP AA  +     P      +S+       AAAAA +++P    A S
Sbjct: 62  PFQAAPAPPPTPQAP-AAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAS 120

Query: 110 Q---GHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGT 148
                 L+ P  PPP  P  S+ ++ AA        AAAA T
Sbjct: 121 TVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAAT 162



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 16/66 (24%)

Query: 47  VELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSS---SPS 103
           V+   ++ PP PPPP             PPP    A  + PP      AAA+++   +P+
Sbjct: 122 VDTAALKQPPAPPPP-------------PPPVSAPAAEAAPPASAATIAAAAATAVVAPT 168

Query: 104 CTPATS 109
            T A +
Sbjct: 169 STVAVA 174



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 12/86 (13%)

Query: 35  PALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAA 94
           PA A   +   L + P    PPPPPP  AP A      + PP     A ++        A
Sbjct: 116 PAAASTVDTAALKQPP--APPPPPPPVSAPAA-----EAAPP-----ASAATIAAAAATA 163

Query: 95  AAASSSSPSCTPATSQGHLRTPAQPP 120
             A +S+ +  P  S    +T ++ P
Sbjct: 164 VVAPTSTVAVAPVASALEKKTKSKGP 189


>gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/102 (34%), Positives = 45/102 (44%), Gaps = 4/102 (3%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
           P   AP PPP P AP AA  +     P      +S+       AAAAA +++P    A S
Sbjct: 62  PFQAAPAPPPTPQAP-AAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAS 120

Query: 110 Q---GHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGT 148
                 L+ P  PPP  P  S+ ++ AA        AAAA T
Sbjct: 121 TVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAAT 162



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 16/66 (24%)

Query: 47  VELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSS---SPS 103
           V+   ++ PP PPPP             PPP    A  + PP      AAA+++   +P+
Sbjct: 122 VDTAALKQPPAPPPP-------------PPPVSAPAAEAAPPASAATIAAAAATAVVAPT 168

Query: 104 CTPATS 109
            T A +
Sbjct: 169 STVAVA 174



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 12/86 (13%)

Query: 35  PALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAA 94
           PA A   +   L + P    PPPPPP  AP A      + PP     A ++        A
Sbjct: 116 PAAASTVDTAALKQPP--APPPPPPPVSAPAA-----EAAPP-----ASAATIAAAAATA 163

Query: 95  AAASSSSPSCTPATSQGHLRTPAQPP 120
             A +S+ +  P  S    +T ++ P
Sbjct: 164 VVAPTSTVAVAPVASALEKKTKSKGP 189


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 40/140 (28%), Positives = 54/140 (38%), Gaps = 9/140 (6%)

Query: 31  PSKRPALAKRYERPTLVELPHVRAPPPPPP------PFAPHAAVSISSSEPPPQQFQAQS 84
           P   P      + P  + +  ++AP  PPP      PF+P A+  +S S  PP Q     
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699

Query: 85  SYPP---GPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPG 141
           + PP    P   A+   S S +  P         P Q PP+ PA+   S  A      P 
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759

Query: 142 AAAAAGTGGTGSDSASLELS 161
             AA       S  ASL +S
Sbjct: 760 LLAAPPLQVPPSPPASLPMS 779



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 10/160 (6%)

Query: 7   PAEEGPSVPKIYKQRSPYS------VLKTF-PSKRPALAKRYERPTLVELPHVRAPPPPP 59
           P+ + P+   ++  ++P+S      V   F P   P ++     P+    P + APP   
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP-PSLAAPPLQV 706

Query: 60  PPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHL--RTPA 117
           PP  P +     S+ PPPQ     ++ P     +  A+   SPS TP      L    P 
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766

Query: 118 QPPPASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSAS 157
           Q PP+ PA+   S  A      P A A        S  AS
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 14/107 (13%)

Query: 31  PSKRPALAKRYERPTLVELPHVRAPPPPP-----------PPFAPHAAVS--ISSSEPPP 77
           P   P+       P L+  P ++ PP PP           PP AP A  +  + +   PP
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804

Query: 78  QQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASP 124
             F  Q+ + P      +  ++  P   P  +   L+ P   PPASP
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-PPASP 850



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 40/143 (27%), Positives = 54/143 (37%), Gaps = 20/143 (13%)

Query: 5   MQPAEEGPSVPKIYKQRSPYSV----LKTFPSKRPALAKRYERPTLVELPHVRAPP---- 56
           M P E   S+     Q  P S+    L+  PS  P   +    P  +  PH+  PP    
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP--LTTPHLETPPCPAP 566

Query: 57  -----PPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPG--PGRAAAAASSSSPSCTPATS 109
                PP P   P      S + PPPQ   A +S P    P    +  ++  P   P  +
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626

Query: 110 QGHLRTPAQP---PPASPAASSS 129
              L+ P  P   PP SP A+ S
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPS 649



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 49/188 (26%), Positives = 68/188 (36%), Gaps = 39/188 (20%)

Query: 5    MQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAP 64
            +Q     P+ P +   R P       P+  P  +    R TL   P     PPPPP  +P
Sbjct: 840  LQVPPSPPASPTLQAPRRP-------PTPGPDTSVSGPRLTLALAPG----PPPPPSRSP 888

Query: 65   HAAVS-------ISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPAT-SQG----- 111
             + +S        SS+   P++ +   S P G   A+    +   +C PA  S+G     
Sbjct: 889  SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948

Query: 112  -HLRTPAQPPPASPAASSSSSFAAVVRY---GPGAAAAA----------GTGGTGSDSAS 157
                 P  P P  PA    S+      Y   GP +A  A          GT G G  +A 
Sbjct: 949  AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG-GKAAAG 1007

Query: 158  LELSAESR 165
                A SR
Sbjct: 1008 AGAGASSR 1015



 Score = 36.2 bits (82), Expect = 0.061
 Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 25/123 (20%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHA 66
           P +  PS P  +  ++P+S   + P                 +  +  PPP  PP     
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLP-----------------MSPLATPPPQAPPVLAAP 838

Query: 67  AVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAA 126
            + +  S P     QA    PP PG      S S P  T A + G    P  PP  SP++
Sbjct: 839 LLQVPPSPPASPTLQAPRR-PPTPG---PDTSVSGPRLTLALAPG----PPPPPSRSPSS 890

Query: 127 SSS 129
           + S
Sbjct: 891 TLS 893



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 7/112 (6%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
           P    PP  PPP A    + +  S P        ++ PP      AA     P   PA+ 
Sbjct: 718 PSATPPPQAPPPLAA-PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 110 QGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELS 161
              +   A+PPP +P A ++    A+    P   A+       S SASL +S
Sbjct: 777 P--MSPLAKPPPQAPPALATPPLQAL----PSPPASFPGQAPFSPSASLPMS 822



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 33/100 (33%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 35  PALAKRYERP-TLVELPH-VRAPPPPPPPFAPHAAVSISS----SEPPPQQFQAQSSYPP 88
           PA+A+R     T V LP    +  P PP   P  +VS +S    +EP P   +  S+   
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--- 230

Query: 89  GPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASS 128
           G G    A+ S S S TP +S       A+  P +PA  S
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 12/131 (9%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPH-----VRAPPPPPPP 61
           P +  PS        +P S+    P   PALA     P L  LP      +  PPP  PP
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALAS----PPLQGLPSPPLSPLATPPPQAPP 623

Query: 62  FAPHAAVSISSSEP--PPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQP 119
                 +    S P  PP    A  S P  P   A     +  S  P+       +P   
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 120 PPASPAASSSS 130
           PP SP+A+  S
Sbjct: 683 PPVSPSATPPS 693



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 14/110 (12%)

Query: 31  PSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQ--------QFQA 82
           P   P ++     P  V  P + APP   PP  P +      ++PPPQ          QA
Sbjct: 741 PPASPPMSPSATPPPRVP-PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 83  QSSYPPG-PGRAAAAASSSSP----SCTPATSQGHLRTPAQPPPASPAAS 127
             S P   PG+A  + S+S P    +  P  +   L  P    P SP AS
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 13/103 (12%)

Query: 50  PHVRAPPPPPPPFAPHA-----AVSISSSEPPPQQFQA-------QSSYPPGPGRAAAAA 97
           P     P PPPP  P A     A      +P  ++          +S+   GP R+A  +
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86

Query: 98  SSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGP 140
           S +  S  PA+ +G    PA+     P  SS    +   R GP
Sbjct: 87  SRNPASRPPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPGP 128



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 45  TLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSC 104
           TL   P +  P P  PP +P A  S+ +   PP    +Q+  PP        A  S  + 
Sbjct: 330 TLPPSPPLATPLPLAPP-SPSAPPSLQTLPSPPATPPSQA--PPSMTTPPMQAPPSLQTI 386

Query: 105 TPATSQGHLRTPAQPPPASPAASSS 129
            P      L +P+   P SP A SS
Sbjct: 387 PPIQVPHSLTSPSLQAPPSPLALSS 411



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 3/60 (5%)

Query: 91  GRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGG 150
           G AA   ++ +P        G   +P  PPP +PAA      A  V   P A  A G GG
Sbjct: 11  GAAARTPAARAPGLLTPRPPG---SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 31/129 (24%), Positives = 42/129 (32%), Gaps = 16/129 (12%)

Query: 7   PAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHA 66
           PA      PK  +   P  V        PAL      P     P      P PPP   +A
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP--DNA 323

Query: 67  AVSISSSEPP-PQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPA 125
           A  + ++ PP P         PP P    +  +  SP             PA PP  +P 
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP-------------PATPPSQAPP 370

Query: 126 ASSSSSFAA 134
           + ++    A
Sbjct: 371 SMTTPPMQA 379


>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
           epsilon, 47kDa [Homo sapiens]
          Length = 357

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 52  VRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGR-AAAAASSSSPSCTPATSQ 110
           V APP  P P    A  S+ +  P P      ++ P      AAAAA++++P  TPA++Q
Sbjct: 8   VSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQ 67

Query: 111 GHLRTPAQPPPASPAASSSSSFAAVVRYGP 140
              +TPA P    PA         VVR  P
Sbjct: 68  APAQTPA-PALPGPALPGPFPGGRVVRLHP 96



 Score = 32.7 bits (73), Expect = 0.67
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 17/81 (20%)

Query: 84  SSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAA 143
           S+ P  P    AAA +S P+ TPA        PA  P  + A +SSS           AA
Sbjct: 9   SAPPATPTPVPAAAPASVPAPTPA--------PAAAPVPAAAPASSSD---------PAA 51

Query: 144 AAAGTGGTGSDSASLELSAES 164
           AAA T   G   AS +  A++
Sbjct: 52  AAAATAAPGQTPASAQAPAQT 72


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 10/75 (13%)

Query: 55  PPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLR 114
           PPPPPPP     ++   +  PPP     Q++ PP P     +ASS +P   P  S+    
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPP----PQNNKPPVPSTPRPSASSQAPPPPPPPSR---- 315

Query: 115 TPAQPPPASPAASSS 129
               PPP  P++S +
Sbjct: 316 --PGPPPLPPSSSGN 328



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 9/90 (10%)

Query: 53  RAPPPPPPP-------FAPHAAVSISSSEPPPQQFQAQSSYP--PGPGRAAAAASSSSPS 103
           +APPPPPPP         P ++ +  +   P +     SS P  P PGR+       S  
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364

Query: 104 CTPATSQGHLRTPAQPPPASPAASSSSSFA 133
             P       R+   PPP   + + S+S A
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 16/85 (18%)

Query: 51  HVRAPPPPPP-------PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPS 103
           H  A PPPPP       P  P  + S  +  PPP         P  PG      SSS   
Sbjct: 278 HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP--------PSRPGPPPLPPSSSGND 329

Query: 104 CTPATSQGHLRTPAQPPP-ASPAAS 127
            TP   Q +L   +  PP  SP  S
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPGRS 354



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 31/112 (27%), Positives = 43/112 (38%), Gaps = 19/112 (16%)

Query: 23  PYSVLKTFPSK-RPALAKRYER--PTLVELPHVRAPPPPPPPFAPHAAVS---------- 69
           P S+    PS  RP  +  + R  P +   P   +P P PPPF  +   +          
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP 239

Query: 70  ISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPP 121
           +SSS P    F  +   PP P R  A      P   P  ++  +   A PPP
Sbjct: 240 LSSSSP----FSNRPPLPPTPSR--ALDDKPPPPPPPVGNRPSIHREAVPPP 285



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 28/122 (22%), Positives = 43/122 (35%), Gaps = 27/122 (22%)

Query: 31  PSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSI------------------SS 72
           PS+RP        P + + P    P PPPPP + + + S                   S 
Sbjct: 361 PSERPP-------PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413

Query: 73  SEPP--PQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSS 130
             PP  P +  A +  PP P  +       SP      S+ +    +  PP  P   ++ 
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTK 473

Query: 131 SF 132
           S+
Sbjct: 474 SY 475


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 10/75 (13%)

Query: 55  PPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLR 114
           PPPPPPP     ++   +  PPP     Q++ PP P     +ASS +P   P  S+    
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPP----PQNNKPPVPSTPRPSASSQAPPPPPPPSR---- 315

Query: 115 TPAQPPPASPAASSS 129
               PPP  P++S +
Sbjct: 316 --PGPPPLPPSSSGN 328



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 9/90 (10%)

Query: 53  RAPPPPPPP-------FAPHAAVSISSSEPPPQQFQAQSSYP--PGPGRAAAAASSSSPS 103
           +APPPPPPP         P ++ +  +   P +     SS P  P PGR+       S  
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364

Query: 104 CTPATSQGHLRTPAQPPPASPAASSSSSFA 133
             P       R+   PPP   + + S+S A
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 16/85 (18%)

Query: 51  HVRAPPPPPP-------PFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPS 103
           H  A PPPPP       P  P  + S  +  PPP         P  PG      SSS   
Sbjct: 278 HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP--------PSRPGPPPLPPSSSGND 329

Query: 104 CTPATSQGHLRTPAQPPP-ASPAAS 127
            TP   Q +L   +  PP  SP  S
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPGRS 354



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 31/112 (27%), Positives = 43/112 (38%), Gaps = 19/112 (16%)

Query: 23  PYSVLKTFPSK-RPALAKRYER--PTLVELPHVRAPPPPPPPFAPHAAVS---------- 69
           P S+    PS  RP  +  + R  P +   P   +P P PPPF  +   +          
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP 239

Query: 70  ISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPP 121
           +SSS P    F  +   PP P R  A      P   P  ++  +   A PPP
Sbjct: 240 LSSSSP----FSNRPPLPPTPSR--ALDDKPPPPPPPVGNRPSIHREAVPPP 285



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 28/122 (22%), Positives = 43/122 (35%), Gaps = 27/122 (22%)

Query: 31  PSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSI------------------SS 72
           PS+RP        P + + P    P PPPPP + + + S                   S 
Sbjct: 361 PSERPP-------PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413

Query: 73  SEPP--PQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSS 130
             PP  P +  A +  PP P  +       SP      S+ +    +  PP  P   ++ 
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTK 473

Query: 131 SF 132
           S+
Sbjct: 474 SY 475


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 10/103 (9%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
            P    PP  PPP           +EPP   F    S P  P  AAAA +   P C  A  
Sbjct: 994  PPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPP--AAAATAVGPPLCRLAFE 1051

Query: 110  QGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGGTG 152
                  PA+ P + P +            GPGA  A GTGG G
Sbjct: 1052 DESPPAPARWPRSDPESQPL--------LGPGAGGAGGTGGAG 1086



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 30/117 (25%), Positives = 36/117 (30%), Gaps = 23/117 (19%)

Query: 54   APPPPPPPFAPHAAVSISSSEPPPQQF------------QAQSSYPPGPGRAAAAASSSS 101
            A PPPPP   P  A       P P  F            + + + PPG    A       
Sbjct: 906  AKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYY 965

Query: 102  PSCTP-----------ATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAG 147
                P           A  +G    P  PP A P      S+ A+VR    A   AG
Sbjct: 966  GPIEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAG 1022


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 46/158 (29%), Positives = 58/158 (36%), Gaps = 14/158 (8%)

Query: 6    QPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRY-------ERPTLVELPHVRAPPPP 58
            +P+ + P   K      P    +   S RP  A R          PT  E      P PP
Sbjct: 1171 RPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPP 1230

Query: 59   PPPFAPHAAVSISSSEPP-PQQFQAQSSYPPGPGRAAAAASSSSPSCTPAT---SQGHLR 114
             PP  P      + S PP P   + ++S       A+   SSSS    P     ++G   
Sbjct: 1231 APPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPP 1290

Query: 115  TPAQPPPA---SPAASSSSSFAAVVRYGPGAAAAAGTG 149
            TP  P PA   +P  SS SS        P    AAGTG
Sbjct: 1291 TPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTG 1328



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 31/123 (25%), Positives = 47/123 (38%), Gaps = 8/123 (6%)

Query: 5   MQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPA--LAKRYERP------TLVELPHVRAPP 56
           + P++  PSV     Q+     + +  SK PA   A  +ERP         E P     P
Sbjct: 44  LAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCP 103

Query: 57  PPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTP 116
             P P  PH    + S + PP   + ++S PPG  R  +   S       +     ++ P
Sbjct: 104 ESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLP 163

Query: 117 AQP 119
             P
Sbjct: 164 LPP 166



 Score = 36.2 bits (82), Expect = 0.061
 Identities = 27/101 (26%), Positives = 37/101 (36%), Gaps = 1/101 (0%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
            P   AP   P    P    ++++S  PP         PP P  A  A +S  PS T  + 
Sbjct: 1102 PTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKG-PPAPATATPAPTSPFPSATAGSM 1160

Query: 110  QGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGG 150
               L  P    P+  A     +  A +  G   A A+G  G
Sbjct: 1161 TYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPG 1201



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 8/93 (8%)

Query: 51  HVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCT---PA 107
           H R P  P PP  P   V+            A S   P    A+AA S S  S T     
Sbjct: 505 HCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASS---PASSSASAATSFSLGSGTFKAQE 561

Query: 108 TSQGHLRTPAQPPPASPAASSSSSFAAVVRYGP 140
           + QG    P +PPP  P A   ++ +   R+ P
Sbjct: 562 SGQGSTAGPLRPPP--PGAGGPATPSKATRFLP 592



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 12/113 (10%)

Query: 50  PHVRAPPPPPPPFAP--HAAVSISSSEPPPQQFQAQSSYPPGPG----RAAAAASSSSPS 103
           P    PP PP  F     +A S S+S P      A +S+  G G    + +   S++ P 
Sbjct: 512 PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPL 571

Query: 104 CTPATSQGHLRTPAQP------PPASPAASSSSSFAAVVRYGPGAAAAAGTGG 150
             P    G   TP++        PA+       S   +   GP   AA  +GG
Sbjct: 572 RPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGG 624



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 7/62 (11%)

Query: 77  PQQFQAQSSYPPGPGRAAAAASSSSPSCT------PATS-QGHLRTPAQPPPASPAASSS 129
           PQQ Q   +  P PG  AAA S  +P+ +      P TS  G +     P P  P   S 
Sbjct: 833 PQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSV 892

Query: 130 SS 131
            S
Sbjct: 893 PS 894



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 24/85 (28%), Positives = 31/85 (36%), Gaps = 10/85 (11%)

Query: 50   PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
            P   AP P PPP    AA       P P    A    P  P   +  A ++ P   P  S
Sbjct: 1529 PGAEAPLPVPPPTGTAAA-------PAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPES 1581

Query: 110  ---QGHLRTPAQPPPASPAASSSSS 131
               Q       QP P  P  S++++
Sbjct: 1582 GPGQPGWEGAPQPSPPPPGPSTAAT 1606



 Score = 28.9 bits (63), Expect = 9.7
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 8/84 (9%)

Query: 73   SEPPPQQFQAQSSYPPGPGRAAAAASSSSPS-----CTPATSQGHLRT--PAQPPPASPA 125
            +E PP   +A    PP  G AAA A + SP+      +P++  G  +   P  PPP S  
Sbjct: 1525 TEQPPGA-EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGP 1583

Query: 126  ASSSSSFAAVVRYGPGAAAAAGTG 149
                   A      P   + A TG
Sbjct: 1584 GQPGWEGAPQPSPPPPGPSTAATG 1607


>gi|13699803 WAS protein family, member 3 [Homo sapiens]
          Length = 502

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 15/95 (15%)

Query: 55  PPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLR 114
           PPPPPPP  P A  +  S    P Q       PP P  A+A+++ ++P   P+T  G L 
Sbjct: 344 PPPPPPPVIPSAQTAFVSPLQMPMQ-------PPFP--ASASSTHAAPPHPPST--GLLV 392

Query: 115 T----PAQPPPASPAASSSSSFAAVVRYGPGAAAA 145
           T    P  PPP        SS ++   +GP  A A
Sbjct: 393 TAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEA 427



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 10/109 (9%)

Query: 31  PSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGP 90
           PS + A     + P     P   +     PP  P   + +++  PPP         PPGP
Sbjct: 353 PSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTA--PPPPGPPPPPPGPPGP 410

Query: 91  GRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYG 139
           G    ++ SSSP   P  ++   + PAQP    P + + S   A +R G
Sbjct: 411 G----SSLSSSPMHGPPVAEAKRQEPAQP----PISDARSDLLAAIRMG 451


>gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo
           sapiens]
          Length = 963

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 19/194 (9%)

Query: 66  AAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPA 125
           + V+ S  +PPPQQ Q Q    P P + A A SSSS +   A S             S +
Sbjct: 23  SGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSSTSAAAAS-------------SSS 69

Query: 126 ASSSSSFAAVVRYGPGAAAAAGTGGTGSDSASLELSAESRMILDAFAQQC-SRVLSLLNC 184
           +S+S+S A  V  G   +A  G  G G   A ++++  +   +D  +  C  R+ SL   
Sbjct: 70  SSTSTSMAVAVASG---SAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLK 126

Query: 185 GGKLLD--SNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQTSDNVDIEMQYMQRKQQT 242
              +L        S++  VK +GS    R     +      +T   +   +QY    ++ 
Sbjct: 127 KLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRD 186

Query: 243 SAFLRVFTDSLQNY 256
           +  L++     + Y
Sbjct: 187 ANKLQIMLQRRKRY 200



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 4/68 (5%)

Query: 50  PHVRAPPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATS 109
           P  +   PP  P  P  A + SSS        + SS       A A AS S+P   P   
Sbjct: 34  PQQQQQQPPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGP--- 90

Query: 110 QGHLRTPA 117
            G  RTPA
Sbjct: 91  -GPGRTPA 97



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 15/41 (36%), Positives = 22/41 (53%)

Query: 89  GPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSS 129
           G G  +   S + PS +P +S G  R     PP+SP+ SS+
Sbjct: 765 GDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSA 805


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 25/123 (20%)

Query: 9   EEGPSVPKIYK---QRSPYSVLKTFP----SKRPALAKRYERPTLVELPHVRAPPPPPPP 61
           E  P +P+ +    +++P  V    P    S  P+L      P   + P   A PPPPPP
Sbjct: 271 ESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPP 330

Query: 62  FAPHAAVSISSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPP 121
              + A     + PPP  ++   S PP  G+     S               RTPA PPP
Sbjct: 331 VIRNGA---RDAPPPPPPYRMHGSEPPSRGKPPPPPS---------------RTPAGPPP 372

Query: 122 ASP 124
             P
Sbjct: 373 PPP 375



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 37/135 (27%), Positives = 53/135 (39%), Gaps = 18/135 (13%)

Query: 12  PSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVEL---PHVRAPPPPPPPFAPHAAV 68
           P  P   +  +P + L    SK PA  +    P        P    PP PPP   P + V
Sbjct: 178 PPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPV 237

Query: 69  SI------SSSEPPPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTP------ 116
           +I       S  PPP  ++     P GP   ++  + S+P      +  H +TP      
Sbjct: 238 NIRTGPSGQSLAPPPPPYRQPPGVPNGP---SSPTNESAPELPQRHNSLHRKTPGPVRGL 294

Query: 117 AQPPPASPAASSSSS 131
           A PPP S + S  S+
Sbjct: 295 APPPPTSASPSLLSN 309



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 24/129 (18%)

Query: 3   EEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPP--- 59
           + + P  EGP  P   K       ++T PS +                   APPPPP   
Sbjct: 215 QRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSL-----------------APPPPPYRQ 257

Query: 60  PPFAPHAAVSISSSEPP--PQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPA 117
           PP  P+   S ++   P  PQ+  +     PGP R  A    +S S  P+        PA
Sbjct: 258 PPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSAS--PSLLSNRPPPPA 315

Query: 118 QPPPASPAA 126
           + PP+  AA
Sbjct: 316 RDPPSRGAA 324



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 6/120 (5%)

Query: 32  SKRPALAKRYERPTLVELPHVRAPPPPP---PPFAPHAAVSISSSE--PPPQQFQAQSSY 86
           S RP       R +L ELP ++ P  P    P       +  SSS   PPP   +A +  
Sbjct: 131 SGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPP 190

Query: 87  PPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAA 146
            P P  ++ A + +     P T    L    + PPA P      S    +R GP   + A
Sbjct: 191 TPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPS-PVNIRTGPSGQSLA 249



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 28/99 (28%), Positives = 32/99 (32%), Gaps = 19/99 (19%)

Query: 55  PPPPPPPFAPHAAVSISSSEPPPQQFQAQSSYPP---GPGRAAAAASSSSPSCTPATSQG 111
           PPPPPPP  P          PPP   QA +  P       R   A        T      
Sbjct: 4   PPPPPPPPGP---------PPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVT 54

Query: 112 HLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGG 150
           ++   + P    P  SS         YG G AA    GG
Sbjct: 55  NINDRSAPILEKPKGSSGG-------YGSGGAALQPKGG 86


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,345,586
Number of Sequences: 37866
Number of extensions: 1400333
Number of successful extensions: 25487
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 527
Number of HSP's successfully gapped in prelim test: 1361
Number of HSP's that attempted gapping in prelim test: 13592
Number of HSP's gapped (non-prelim): 8224
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.