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Search of human proteins with 22749297
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]
(545 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens] 1170 0.0
gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2 [... 192 9e-49
gi|56550049 uromodulin precursor [Homo sapiens] 190 3e-48
gi|59850812 uromodulin precursor [Homo sapiens] 190 3e-48
gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1 [... 180 3e-45
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 106 6e-23
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 106 6e-23
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 101 2e-21
gi|10190748 CEGP1 protein [Homo sapiens] 100 3e-21
gi|56237021 fibrillin 3 precursor [Homo sapiens] 97 5e-20
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 95 1e-19
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 95 2e-19
gi|19743803 fibulin 5 precursor [Homo sapiens] 92 1e-18
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 92 2e-18
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 92 2e-18
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 92 2e-18
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 92 2e-18
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 92 2e-18
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 92 2e-18
gi|66346695 fibrillin 2 precursor [Homo sapiens] 91 2e-18
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens] 91 2e-18
gi|119220573 zymogen granule membrane glycoprotein 2 isoform 4 [... 91 4e-18
gi|119220572 zymogen granule membrane glycoprotein 2 isoform 3 [... 91 4e-18
gi|24430141 fibrillin 1 precursor [Homo sapiens] 89 8e-18
gi|11321565 matrilin 3 precursor [Homo sapiens] 89 8e-18
gi|134268640 tectorin alpha precursor [Homo sapiens] 86 7e-17
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 84 3e-16
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 84 3e-16
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 84 3e-16
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 84 3e-16
>gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]
Length = 545
Score = 1170 bits (3027), Expect = 0.0
Identities = 545/545 (100%), Positives = 545/545 (100%)
Query: 1 MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWY 60
MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWY
Sbjct: 1 MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWY 60
Query: 61 HFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVE 120
HFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVE
Sbjct: 61 HFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVE 120
Query: 121 VKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTC 180
VKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTC
Sbjct: 121 VKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTC 180
Query: 181 FDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLG 240
FDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLG
Sbjct: 181 FDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLG 240
Query: 241 SEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNG 300
SEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNG
Sbjct: 241 SEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNG 300
Query: 301 THVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPR 360
THVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPR
Sbjct: 301 THVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPR 360
Query: 361 LYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGI 420
LYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGI
Sbjct: 361 LYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGI 420
Query: 421 EPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPV 480
EPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPV
Sbjct: 421 EPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPV 480
Query: 481 FKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPIR 540
FKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPIR
Sbjct: 481 FKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPIR 540
Query: 541 IDWED 545
IDWED
Sbjct: 541 IDWED 545
>gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2
[Homo sapiens]
Length = 534
Score = 192 bits (487), Expect = 9e-49
Identities = 150/515 (29%), Positives = 214/515 (41%), Gaps = 95/515 (18%)
Query: 14 GTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTF 73
GT + V DPC Y L+EP+R+T++ S G CD +++G WY F G G M
Sbjct: 52 GTPEAHVCFDPCQNYTLLDEPFRSTEN----SAGSQGCDKNMSG-WYRFVGEGGVRMSET 106
Query: 74 CIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRL 133
C+ + C T AP+WLNG+HP GDGI ACA ++GNCC W T V VKACPGGY+VYRL
Sbjct: 107 CVQVHRCQTDAPMWLNGTHPALGDGITNHTACAHWSGNCCFWKTEVLVKACPGGYHVYRL 166
Query: 134 TKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC 193
C Y C+D P TV E++CE
Sbjct: 167 EGTPWCNLRY---------------CTD-------PSTV----------EDKCE------ 188
Query: 194 SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGL 253
K C E CL + C C + L
Sbjct: 189 -------------------------KACRPEE-----------ECLALNSTWGCFCRQDL 212
Query: 254 VLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLEL------FLTNTSCRGVSNGTHVNILF 307
S D H+ Q + C I+V + + L+GGL L +L + +C + N +
Sbjct: 213 N-SSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRDPNCSSILQTEERNWV- 270
Query: 308 SLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEG 367
V I+ N + K T DFIIR + L I C +P +S
Sbjct: 271 --SVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRDTILNINFQCAYPLDMKVSLQ 328
Query: 368 YVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFG-IEPVVHV 426
S L + +G F + +F+D + PY L + LY G I
Sbjct: 329 AALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAVELSVESVLYVGAILEQGDT 388
Query: 427 SGLESLVESCFATPTSKIDEVLKYYLIRDGCVS--DDSVKQYTSRDHLAKHFQVPVFKFV 484
S ++ +C+ATPT +++KY++IR+ C + D ++ + F V +F F
Sbjct: 389 SRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEENGQSSESRFSVQMFMFA 448
Query: 485 GKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRR 519
G + VFLHC + +C L+E +C C R R
Sbjct: 449 G-HYDLVFLHCEIHLCDSLNE--QCQPSCSRSQVR 480
>gi|56550049 uromodulin precursor [Homo sapiens]
Length = 640
Score = 190 bits (482), Expect = 3e-48
Identities = 148/535 (27%), Positives = 226/535 (42%), Gaps = 114/535 (21%)
Query: 20 VALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENH 79
V DPC A+ +L+E WR+T++ + CD + G WY F G G M C+P
Sbjct: 169 VCADPCQAHRTLDEYWRSTEYGEGYA-----CDTDLRG-WYRFVGQGGARMAETCVPVLR 222
Query: 80 CGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVC 139
C T AP+WLNG+HP +GIV R+ACA ++G+CCLW+ +V+VKAC GGYYVY LT P C
Sbjct: 223 CNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPEC 282
Query: 140 FHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVN 199
YC + + E TC + C + +C+ NNG C
Sbjct: 283 HLAYC-------------TDPSSVEGTC----------EECSIDEDCKSNNGRWHCQCKQ 319
Query: 200 LKN-------SYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
N +R ECG + S GK C LG +K +
Sbjct: 320 DFNITDISLLEHRLECGANDMKVSLGK--------------CQLKSLGFDKVF------- 358
Query: 253 LVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVS---NGTHVNILFSL 309
++L+++ C G + N V+++
Sbjct: 359 ----------------------------------MYLSDSRCSGFNDRDNRDWVSVVTPA 384
Query: 310 K--TCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEG 367
+ CGTV+ SN T + + IIR + I C +P +S
Sbjct: 385 RDGPCGTVLTRNETHATYSN--------TLYLADEIIIRDLNIKINFACSYPLDMKVSLK 436
Query: 368 YVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFG-IEPVVHV 426
S L I G+F + +F+ + +PY+ + TL LY G + +
Sbjct: 437 TALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDL 496
Query: 427 SGLESLVESCFATPTSKIDEVLKYYLIRDGC--VSDDSVKQYTSRDHLAKHFQVPVFKFV 484
S L+ +C+ATP+S + LKY++I+D C D +++ + + F V +F+F
Sbjct: 497 SRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFA 556
Query: 485 GKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPI 539
G ++ V+LHC V +C ++E +C C R D Q + L GPI
Sbjct: 557 G-NYDLVYLHCEVYLCDTMNE--KCKPTCSGTRFRSGSVID----QSRVLNLGPI 604
Score = 37.4 bits (85), Expect = 0.035
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENEC-EQNNGGCSEI--CVNLKNSYRCECG 209
+ SC +T C C G L P C D +EC E C + CVN+ SY C C
Sbjct: 80 NSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECP 250
G R DG CE C + G C+ C P
Sbjct: 139 AG--YRGDGWHCE----CSPGSCGPGLDCVPEGDALVCADP 173
Score = 36.6 bits (83), Expect = 0.061
Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 17/104 (16%)
Query: 184 NECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCH---NNNGGCSHSCLG 240
+EC N C + C C G DG TC D++ C +N + SC+
Sbjct: 33 SECHSN-----ATCTEDEAVTTCTCQEG--FTGDGLTCVDLDECAIPGAHNCSANSSCVN 85
Query: 241 SEKGYQCECPRGLVLS-----EDNHTCQVPVL--CKSNAIEVNI 277
+ + C CP G LS D C P L C + A VN+
Sbjct: 86 TPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNV 129
>gi|59850812 uromodulin precursor [Homo sapiens]
Length = 640
Score = 190 bits (482), Expect = 3e-48
Identities = 148/535 (27%), Positives = 226/535 (42%), Gaps = 114/535 (21%)
Query: 20 VALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENH 79
V DPC A+ +L+E WR+T++ + CD + G WY F G G M C+P
Sbjct: 169 VCADPCQAHRTLDEYWRSTEYGEGYA-----CDTDLRG-WYRFVGQGGARMAETCVPVLR 222
Query: 80 CGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVC 139
C T AP+WLNG+HP +GIV R+ACA ++G+CCLW+ +V+VKAC GGYYVY LT P C
Sbjct: 223 CNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPEC 282
Query: 140 FHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVN 199
YC + + E TC + C + +C+ NNG C
Sbjct: 283 HLAYC-------------TDPSSVEGTC----------EECSIDEDCKSNNGRWHCQCKQ 319
Query: 200 LKN-------SYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
N +R ECG + S GK C LG +K +
Sbjct: 320 DFNITDISLLEHRLECGANDMKVSLGK--------------CQLKSLGFDKVF------- 358
Query: 253 LVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVS---NGTHVNILFSL 309
++L+++ C G + N V+++
Sbjct: 359 ----------------------------------MYLSDSRCSGFNDRDNRDWVSVVTPA 384
Query: 310 K--TCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEG 367
+ CGTV+ SN T + + IIR + I C +P +S
Sbjct: 385 RDGPCGTVLTRNETHATYSN--------TLYLADEIIIRDLNIKINFACSYPLDMKVSLK 436
Query: 368 YVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFG-IEPVVHV 426
S L I G+F + +F+ + +PY+ + TL LY G + +
Sbjct: 437 TALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDL 496
Query: 427 SGLESLVESCFATPTSKIDEVLKYYLIRDGC--VSDDSVKQYTSRDHLAKHFQVPVFKFV 484
S L+ +C+ATP+S + LKY++I+D C D +++ + + F V +F+F
Sbjct: 497 SRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFA 556
Query: 485 GKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPI 539
G ++ V+LHC V +C ++E +C C R D Q + L GPI
Sbjct: 557 G-NYDLVYLHCEVYLCDTMNE--KCKPTCSGTRFRSGSVID----QSRVLNLGPI 604
Score = 37.4 bits (85), Expect = 0.035
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENEC-EQNNGGCSEI--CVNLKNSYRCECG 209
+ SC +T C C G L P C D +EC E C + CVN+ SY C C
Sbjct: 80 NSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECP 250
G R DG CE C + G C+ C P
Sbjct: 139 AG--YRGDGWHCE----CSPGSCGPGLDCVPEGDALVCADP 173
Score = 36.6 bits (83), Expect = 0.061
Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 17/104 (16%)
Query: 184 NECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCH---NNNGGCSHSCLG 240
+EC N C + C C G DG TC D++ C +N + SC+
Sbjct: 33 SECHSN-----ATCTEDEAVTTCTCQEG--FTGDGLTCVDLDECAIPGAHNCSANSSCVN 85
Query: 241 SEKGYQCECPRGLVLS-----EDNHTCQVPVL--CKSNAIEVNI 277
+ + C CP G LS D C P L C + A VN+
Sbjct: 86 TPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNV 129
>gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1
[Homo sapiens]
Length = 537
Score = 180 bits (457), Expect = 3e-45
Identities = 146/515 (28%), Positives = 209/515 (40%), Gaps = 92/515 (17%)
Query: 14 GTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTF 73
GT + V DPC Y L+EP+R+T++ S G CD +++G WY F G G M
Sbjct: 52 GTPEAHVCFDPCQNYTLLDEPFRSTEN----SAGSQGCDKNMSG-WYRFVGEGGVRMSET 106
Query: 74 CIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRL 133
C+ + C T AP+WLNG+HP GDGI ACA ++GNCC W T V VKACPGG
Sbjct: 107 CVQVHRCQTDAPMWLNGTHPALGDGITNHTACAHWSGNCCFWKTEVLVKACPGG------ 160
Query: 134 TKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC 193
+HVY T C TV R E++CE
Sbjct: 161 ------YHVY--------------RLEGTPWCNLRYCTV---PRDPSTVEDKCE------ 191
Query: 194 SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGL 253
K C E CL + C C + L
Sbjct: 192 -------------------------KACRPEE-----------ECLALNSTWGCFCRQDL 215
Query: 254 VLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLEL------FLTNTSCRGVSNGTHVNILF 307
S D H+ Q + C I+V + + L+GGL L +L + +C + N +
Sbjct: 216 N-SSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRDPNCSSILQTEERNWV- 273
Query: 308 SLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEG 367
V I+ N + K T DFIIR + L I C +P +S
Sbjct: 274 --SVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRDTILNINFQCAYPLDMKVSLQ 331
Query: 368 YVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFG-IEPVVHV 426
S L + +G F + +F+D + PY L + LY G I
Sbjct: 332 AALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAVELSVESVLYVGAILEQGDT 391
Query: 427 SGLESLVESCFATPTSKIDEVLKYYLIRDGCVS--DDSVKQYTSRDHLAKHFQVPVFKFV 484
S ++ +C+ATPT +++KY++IR+ C + D ++ + F V +F F
Sbjct: 392 SRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEENGQSSESRFSVQMFMFA 451
Query: 485 GKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRR 519
G + VFLHC + +C L+E +C C R R
Sbjct: 452 G-HYDLVFLHCEIHLCDSLNE--QCQPSCSRSQVR 483
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 106 bits (264), Expect = 6e-23
Identities = 46/122 (37%), Positives = 69/122 (56%), Gaps = 3/122 (2%)
Query: 152 DEDCHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCEC 208
D C C +T + C C+ G ++ D +TC + C ++ GC CVN+ S+ C+C
Sbjct: 451 DHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQC 510
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLC 268
G VLRSDGKTC ++ C + GC HSC+ SE + C+C G +L ED TC+ +C
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 269 KS 270
++
Sbjct: 571 QA 572
Score = 102 bits (254), Expect = 9e-22
Identities = 57/172 (33%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Query: 95 EGDGIVQRQACASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHV-YCGHFYDI 150
+G V CAS N C C+ + C G+ + K C + YC
Sbjct: 314 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKK--TCTKIDYCASSNHG 371
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGV 210
C +C + D+ C C G L PD++TC N C N GC CVN++ SY C C
Sbjct: 372 CQHECVNT-DDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHR 430
Query: 211 GRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
G L +GKTC V+ C + GC CL +E + C+C G +++ED TC
Sbjct: 431 GYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTC 482
Score = 100 bits (248), Expect = 4e-21
Identities = 59/173 (34%), Positives = 80/173 (46%), Gaps = 13/173 (7%)
Query: 105 CASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHV-YCGHFYDICDEDCHGSCS 160
CA + C CL V C G+ + K C V YC + D C SC
Sbjct: 447 CAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLK--TCSRVDYCL----LSDHGCEYSCV 500
Query: 161 DTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSD 217
+ C C G VL D +TC + C + GC CV+ ++S+ C+C G +LR D
Sbjct: 501 NMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 560
Query: 218 GKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKS 270
GKTC + C + GC H C+ S+ Y CEC G L+ED C+ +CKS
Sbjct: 561 GKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKS 613
Score = 99.0 bits (245), Expect = 1e-20
Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 17/204 (8%)
Query: 73 FCIPENHCGTHAPVWLNGSHPL---EGDGI-------VQRQACASFNGNC---CLWNTTV 119
+C ENH H V +GS+ EG + + CAS N C C+
Sbjct: 323 YCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDS 382
Query: 120 EVKACPGGYYVYRLTKPSVCFHV-YCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQ 178
C G+ + K C + YC C+ +C + ++ C C G L P+ +
Sbjct: 383 YSCHCLKGFTLNPDKK--TCRRINYCALNKPGCEHECV-NMEESYYCRCHRGYTLDPNGK 439
Query: 179 TCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSC 238
TC + C Q + GC ++C+N ++S+ C+C G ++ D KTC V+ C ++ GC +SC
Sbjct: 440 TCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC 499
Query: 239 LGSEKGYQCECPRGLVLSEDNHTC 262
+ ++ + C+CP G VL D TC
Sbjct: 500 VNMDRSFACQCPEGHVLRSDGKTC 523
Score = 95.9 bits (237), Expect = 8e-20
Identities = 44/115 (38%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 152 DEDCHGSC---SDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCEC 208
D C SC D+ C C G +L D +TC ++ C+ + GC ICVN +SY CEC
Sbjct: 533 DHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCEC 592
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
G L DGK C + C + + GC H C+ + Y C+C G VL+ED C+
Sbjct: 593 LEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 647
Score = 95.1 bits (235), Expect = 1e-19
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 17/176 (9%)
Query: 105 CASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDIC---DEDCHGS 158
C++ NC C+ V C GY + + + C D+C D +C
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILN--SDQTTC------RIQDLCAMEDHNCEQL 293
Query: 159 CSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLR 215
C + C C G L D + C + C N GC CVN SY C+C G L
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALN 353
Query: 216 SDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
D KTC ++ C ++N GC H C+ ++ Y C C +G L+ D TC+ C N
Sbjct: 354 PDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Score = 93.2 bits (230), Expect = 5e-19
Identities = 41/129 (31%), Positives = 63/129 (48%), Gaps = 3/129 (2%)
Query: 146 HFYDICDEDCHGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKN 202
H + +C C + + C C G +L D+ TC ++ C + C ++CVN+
Sbjct: 240 HMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPG 299
Query: 203 SYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
S+ C+C G L DGK C V+ C + N GC H C+ ++ Y C+C G L+ D TC
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 263 QVPVLCKSN 271
C S+
Sbjct: 360 TKIDYCASS 368
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 106 bits (264), Expect = 6e-23
Identities = 46/122 (37%), Positives = 69/122 (56%), Gaps = 3/122 (2%)
Query: 152 DEDCHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCEC 208
D C C +T + C C+ G ++ D +TC + C ++ GC CVN+ S+ C+C
Sbjct: 451 DHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQC 510
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLC 268
G VLRSDGKTC ++ C + GC HSC+ SE + C+C G +L ED TC+ +C
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 269 KS 270
++
Sbjct: 571 QA 572
Score = 102 bits (254), Expect = 9e-22
Identities = 57/172 (33%), Positives = 79/172 (45%), Gaps = 7/172 (4%)
Query: 95 EGDGIVQRQACASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHV-YCGHFYDI 150
+G V CAS N C C+ + C G+ + K C + YC
Sbjct: 314 DGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKK--TCTKIDYCASSNHG 371
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGV 210
C +C + D+ C C G L PD++TC N C N GC CVN++ SY C C
Sbjct: 372 CQHECVNT-DDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHR 430
Query: 211 GRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
G L +GKTC V+ C + GC CL +E + C+C G +++ED TC
Sbjct: 431 GYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTC 482
Score = 100 bits (248), Expect = 4e-21
Identities = 59/173 (34%), Positives = 80/173 (46%), Gaps = 13/173 (7%)
Query: 105 CASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHV-YCGHFYDICDEDCHGSCS 160
CA + C CL V C G+ + K C V YC + D C SC
Sbjct: 447 CAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLK--TCSRVDYCL----LSDHGCEYSCV 500
Query: 161 DTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSD 217
+ C C G VL D +TC + C + GC CV+ ++S+ C+C G +LR D
Sbjct: 501 NMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRED 560
Query: 218 GKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKS 270
GKTC + C + GC H C+ S+ Y CEC G L+ED C+ +CKS
Sbjct: 561 GKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKS 613
Score = 99.0 bits (245), Expect = 1e-20
Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 17/204 (8%)
Query: 73 FCIPENHCGTHAPVWLNGSHPL---EGDGI-------VQRQACASFNGNC---CLWNTTV 119
+C ENH H V +GS+ EG + + CAS N C C+
Sbjct: 323 YCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDS 382
Query: 120 EVKACPGGYYVYRLTKPSVCFHV-YCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQ 178
C G+ + K C + YC C+ +C + ++ C C G L P+ +
Sbjct: 383 YSCHCLKGFTLNPDKK--TCRRINYCALNKPGCEHECV-NMEESYYCRCHRGYTLDPNGK 439
Query: 179 TCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSC 238
TC + C Q + GC ++C+N ++S+ C+C G ++ D KTC V+ C ++ GC +SC
Sbjct: 440 TCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC 499
Query: 239 LGSEKGYQCECPRGLVLSEDNHTC 262
+ ++ + C+CP G VL D TC
Sbjct: 500 VNMDRSFACQCPEGHVLRSDGKTC 523
Score = 95.9 bits (237), Expect = 8e-20
Identities = 44/115 (38%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 152 DEDCHGSC---SDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCEC 208
D C SC D+ C C G +L D +TC ++ C+ + GC ICVN +SY CEC
Sbjct: 533 DHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCEC 592
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
G L DGK C + C + + GC H C+ + Y C+C G VL+ED C+
Sbjct: 593 LEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCK 647
Score = 95.1 bits (235), Expect = 1e-19
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 17/176 (9%)
Query: 105 CASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDIC---DEDCHGS 158
C++ NC C+ V C GY + + + C D+C D +C
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILN--SDQTTC------RIQDLCAMEDHNCEQL 293
Query: 159 CSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLR 215
C + C C G L D + C + C N GC CVN SY C+C G L
Sbjct: 294 CVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALN 353
Query: 216 SDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
D KTC ++ C ++N GC H C+ ++ Y C C +G L+ D TC+ C N
Sbjct: 354 PDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Score = 93.2 bits (230), Expect = 5e-19
Identities = 41/129 (31%), Positives = 63/129 (48%), Gaps = 3/129 (2%)
Query: 146 HFYDICDEDCHGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKN 202
H + +C C + + C C G +L D+ TC ++ C + C ++CVN+
Sbjct: 240 HMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPG 299
Query: 203 SYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
S+ C+C G L DGK C V+ C + N GC H C+ ++ Y C+C G L+ D TC
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 263 QVPVLCKSN 271
C S+
Sbjct: 360 TKIDYCASS 368
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 101 bits (252), Expect = 2e-21
Identities = 52/124 (41%), Positives = 69/124 (55%), Gaps = 12/124 (9%)
Query: 149 DICDE---DCH--GSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQN--NGGCSEICV 198
D C E DCH C +T + C C PG G +Q C D +ECE + NGGC C+
Sbjct: 35 DECSEGTDDCHIDAICQNTPKSYKCLCKPG-YKGEGKQ-CEDIDECENDYYNGGCVHECI 92
Query: 199 NLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSED 258
N+ +YRC C G +L DG C DV+ C +NNGGC C+ + Y+C+C G LS++
Sbjct: 93 NIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDN 152
Query: 259 NHTC 262
HTC
Sbjct: 153 QHTC 156
Score = 98.2 bits (243), Expect = 2e-20
Identities = 46/112 (41%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 155 CHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
C SC DT C C L D +TC + C NNGGC C + RC C VG
Sbjct: 213 CQHSCEDTDTGPTCGCHQKYALHSDGRTCIET--CAVNNGGCDRTCKDTATGVRCSCPVG 270
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
L+ DGKTC+D+ C NNGGC H C + ++C C +G L D TCQ
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQ 322
Score = 95.9 bits (237), Expect = 8e-20
Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 4/120 (3%)
Query: 155 CHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
C +C DT+ C+C G L PD +TC D NEC NNGGC C N S+ C C G
Sbjct: 252 CDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKG 311
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
L +D +TC+D++ C + C H C+ S +QC C RG +L H V SN
Sbjct: 312 YKLLTDERTCQDIDEC-SFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSN 370
Score = 80.1 bits (196), Expect = 5e-15
Identities = 49/166 (29%), Positives = 62/166 (37%), Gaps = 52/166 (31%)
Query: 149 DICDEDCH-GSC-------SDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNL 200
D C+ D + G C CTC G +L D C D +EC+ NNGGC +ICVN
Sbjct: 76 DECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNA 135
Query: 201 KNSYRCECGVGRVLRSDGKTC----------------------EDVEG------------ 226
SY C+C G L + TC E +G
Sbjct: 136 MGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDL 195
Query: 227 ----------CHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C+ NGGC HSC ++ G C C + L D TC
Sbjct: 196 AQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC 241
Score = 74.3 bits (181), Expect = 3e-13
Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 182 DENECEQNNGGC--SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNN--NGGCSHS 237
D +EC + C IC N SY+C C G + +GK CED++ C N+ NGGC H
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPG--YKGEGKQCEDIDECENDYYNGGCVHE 90
Query: 238 CLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
C+ Y+C C G +L+ D H C C+ N
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDN 124
Score = 63.5 bits (153), Expect = 5e-10
Identities = 54/177 (30%), Positives = 70/177 (39%), Gaps = 10/177 (5%)
Query: 105 CASFNGNCCLW--NTTVEVKA-CPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSD 161
C NG C + NT + C GY + LT C + F CD C S
Sbjct: 286 CLVNNGGCDHFCRNTVGSFECGCRKGYKL--LTDERTCQDIDECSFERTCDHICINS-PG 342
Query: 162 TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTC 221
+ +C C G +L C D +EC +NG C + CVN K SY C C GR L +GK C
Sbjct: 343 SFQCLCHRGYILYGTTH-CGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDC 401
Query: 222 EDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIP 278
+ C + + L K E LS HT VP S + +P
Sbjct: 402 VETGKCLSRAKTSPRAQLSCSKAGGVE---SCFLSCPAHTLFVPDSENSYVLSCGVP 455
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 100 bits (250), Expect = 3e-21
Identities = 50/116 (43%), Positives = 66/116 (56%), Gaps = 8/116 (6%)
Query: 153 EDCHGS--CSDTS---ECTCAPGTVLGPDRQTCFDENEC-EQNNGGCSEICVNLKNSYRC 206
+DCH C +T +C+C PG G RQ C D +EC + NGGC C+N+ +YRC
Sbjct: 54 DDCHADALCQNTPTSYKCSCKPG-YQGEGRQ-CEDIDECGNELNGGCVHDCLNIPGNYRC 111
Query: 207 ECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C G +L DG C DV+ C NNGGC H+C+ Y+C C G LS++ HTC
Sbjct: 112 TCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 89.0 bits (219), Expect = 1e-17
Identities = 43/140 (30%), Positives = 58/140 (41%), Gaps = 31/140 (22%)
Query: 155 CHGSCSDTS---ECTCAPGTVLGPDRQTCFDENE-------------------------- 185
C SC DT+ EC+C P + D ++C + +
Sbjct: 224 CQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLM 283
Query: 186 --CEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEK 243
C NNGGC C + C C VG L+ DGKTC+D++ C NGGC H C
Sbjct: 284 ETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVG 343
Query: 244 GYQCECPRGLVLSEDNHTCQ 263
+ C C +G L D +CQ
Sbjct: 344 SFDCGCKKGFKLLTDEKSCQ 363
Score = 86.7 bits (213), Expect = 5e-17
Identities = 42/109 (38%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Query: 155 CHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
C +C DTS C+C G L D +TC D +EC+ NGGC C N+ S+ C C G
Sbjct: 293 CDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKG 352
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNH 260
L +D K+C+DV+ C + + C HSC+ + C C RG L H
Sbjct: 353 FKLLTDEKSCQDVDEC-SLDRTCDHSCINHPGTFACACNRGYTLYGFTH 400
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/132 (34%), Positives = 59/132 (44%), Gaps = 24/132 (18%)
Query: 149 DICDEDCHGSCSDTSECTCAPGTVLGPDRQTCF-------------DENECEQNNGGCSE 195
D C + +G C +C PG R TCF D +EC +NNGGC
Sbjct: 88 DECGNELNGGC--VHDCLNIPGNY----RCTCFDGFMLAHDGHNCLDVDECLENNGGCQH 141
Query: 196 ICVNLKNSYRCECGVGRVLRSDGKTC----EDVEGCHNNNGGCSHSCLGSEKG-YQCECP 250
CVN+ SY C C G L + TC E+ C N + GCSH C + +G CEC
Sbjct: 142 TCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECR 201
Query: 251 RGLVLSEDNHTC 262
G L+++ C
Sbjct: 202 PGFELAKNQRDC 213
Score = 72.4 bits (176), Expect = 1e-12
Identities = 36/96 (37%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
Query: 170 GTVLGPDRQTCFDENECEQNNGGC--SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGC 227
G GP D +EC Q C +C N SY+C C G + +G+ CED++ C
Sbjct: 37 GRAAGPQE----DVDECAQGLDDCHADALCQNTPTSYKCSCKPG--YQGEGRQCEDIDEC 90
Query: 228 HNN-NGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
N NGGC H CL Y+C C G +L+ D H C
Sbjct: 91 GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Score = 70.5 bits (171), Expect = 4e-12
Identities = 76/280 (27%), Positives = 100/280 (35%), Gaps = 62/280 (22%)
Query: 53 NHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWL------------NGSHPLEGDGIV 100
NH NG H D C P+ T L N + ++GD V
Sbjct: 218 NHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRV 277
Query: 101 QR----QACASFNGNC---CLWNTTVEVKACPGGYYVYR-----------LTKPSVCFHV 142
+R + CA NG C C +T +CP G+ + T+ C H
Sbjct: 278 KRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDH- 336
Query: 143 YCGHFYDICDEDC---------HGSCSDTSEC----TCAPGTVLGPDRQTCF-------- 181
+C + D C SC D EC TC + P C
Sbjct: 337 FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYTLY 396
Query: 182 ------DENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGC--HNNNGG 233
D NEC NNGGC ++CVN SY C+C G L + K C +V+G + +
Sbjct: 397 GFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPR 456
Query: 234 CSHSCLGSEKGYQC--ECPRGLVLSEDNHTCQVPVLCKSN 271
S C S G C C G+ LS D T + V K N
Sbjct: 457 VSLHCGKSGGGDGCFLRCHSGIHLSSDVTTIRTSVTFKLN 496
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 96.7 bits (239), Expect = 5e-20
Identities = 52/144 (36%), Positives = 68/144 (47%), Gaps = 10/144 (6%)
Query: 124 CPGGYYVYRLTKPSVCFHV-YCGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQT 179
CP G+ + K + C + C +C HG C + +C+C G PDRQ
Sbjct: 1098 CPPGHEL--TAKGTACEDIDECSLSDGLCP---HGQCVNVIGAFQCSCHAGFQSTPDRQG 1152
Query: 180 CFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS-C 238
C D NEC NGGC C+N + SYRC CG G L DG+ C DV+ C N C C
Sbjct: 1153 CVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHC 1212
Query: 239 LGSEKGYQCECPRGLVLSEDNHTC 262
G++C C G + + D TC
Sbjct: 1213 TNMPGGHRCLCYDGFMATPDMRTC 1236
Score = 80.1 bits (196), Expect = 5e-15
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 157 GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGR 212
G+C++T +C C PG L C D +EC ++G C CVN+ +++C C G
Sbjct: 1085 GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGF 1144
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
D + C D+ C NGGC C+ +E Y+C C +G L D C C+ N
Sbjct: 1145 QSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEEN 1203
Score = 79.0 bits (193), Expect = 1e-14
Identities = 43/125 (34%), Positives = 57/125 (45%), Gaps = 4/125 (3%)
Query: 156 HGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCS-EICVNLKNSYRCECGVG 211
HG C + T C C PG P RQ C D +EC + G C CVN + S++C C G
Sbjct: 460 HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAG 519
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
L DGK C D C + + CL + + C C G +L+ H C C++
Sbjct: 520 FELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTP 579
Query: 272 AIEVN 276
I VN
Sbjct: 580 GICVN 584
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 14/161 (8%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGR 212
HG C ++ C C G TC D +EC Q C+ +C N K S+ C C G
Sbjct: 2376 HGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGY 2435
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSE----DNHTCQV-PVL 267
+L DG+TC+D++ C + C C+ + + C CP G DN C P
Sbjct: 2436 LLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGP 2495
Query: 268 CKSNAIEVNIPR----ELVGGLELFLTNTSCRGVS--NGTH 302
C ++ N P E G L + C V+ +G H
Sbjct: 2496 CGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPH 2536
Score = 73.6 bits (179), Expect = 4e-13
Identities = 44/116 (37%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 154 DCHGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEI--CVNLKNSYRCEC 208
D H SC + + C C PG V D C D +EC CS C+N+ SYRC C
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC 1349
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQ 263
G DG CED + C N C + CL + GY+CEC G +ED+ CQ
Sbjct: 1350 RQG--FAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQ 1403
Score = 73.2 bits (178), Expect = 6e-13
Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 155 CH-GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGV 210
CH G C +T +C C G L PD + C D NEC + + +C+N S+ C C
Sbjct: 500 CHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKP 559
Query: 211 GRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
G +L G C D++ C + C +E ++C+C GL + D C
Sbjct: 560 GFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Score = 72.0 bits (175), Expect = 1e-12
Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 7/111 (6%)
Query: 157 GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGR 212
G C +T+ C C G L D + C D NEC G C C NL+ S+RC C G
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF 1960
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSH-SCLGSEKGYQCECPRGLVLSEDNHTC 262
++SD C D++ C C +C S +QC CP G VLS++ H C
Sbjct: 1961 QVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 71.2 bits (173), Expect = 2e-12
Identities = 72/270 (26%), Positives = 105/270 (38%), Gaps = 41/270 (15%)
Query: 42 LDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQ 101
+DE Q P +C VNG H T G + C+ GT V ++ G ++
Sbjct: 573 IDECQTPGIC---VNG---HCTNTEG-SFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIE 625
Query: 102 RQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSD 161
+ +CA + PG +TK C F + C + C S
Sbjct: 626 KGSCA---------------RPFPG-----TVTKSECCCANPDHGFGEPC-QLCPAKDSA 664
Query: 162 TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKT 220
+ C+ G + D + D NEC + C+ +C NL+ SYRC C +G + GK
Sbjct: 665 EFQALCSSGLGITTDGR---DINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKD 721
Query: 221 CEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPR 279
C DV+ C N+ C + C S Y C CP G +D C+ C S+ + R
Sbjct: 722 CTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCR 781
Query: 280 ELVG--------GLELFLTNTSCRGVSNGT 301
L G G L + T C + GT
Sbjct: 782 NLAGSYTCKCGPGSRLDPSGTFCLDSTKGT 811
Score = 68.2 bits (165), Expect = 2e-11
Identities = 51/165 (30%), Positives = 69/165 (41%), Gaps = 11/165 (6%)
Query: 98 GIVQRQACASFNGNC---CLWNTTVEVK-ACPGGYYVYRLTKPSVCFHV-YCGHFYDICD 152
G V C NG C C+ NT + +C GY + + C V C +CD
Sbjct: 1152 GCVDINECRVQNGGCDVHCI-NTEGSYRCSCGQGYSL--MPDGRACADVDECEENPRVCD 1208
Query: 153 EDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVG 211
+ + C C G + PD +TC D +EC+ N C C N K S+ C C +G
Sbjct: 1209 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG 1268
Query: 212 RVLRSDGKTCEDVEGCHNNNGGC-SH-SCLGSEKGYQCECPRGLV 254
++R C DV+ C C SH SCL + C C G V
Sbjct: 1269 YMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313
Score = 65.5 bits (158), Expect = 1e-10
Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 44/156 (28%)
Query: 149 DICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCE 207
++C ++ GS + C G V GPD + D NEC +N G C+ +CVN S+RCE
Sbjct: 2054 ELCPQE--GSAAFQELCPFGHGAVPGPD-DSREDVNECAENPGVCTNGVCVNTDGSFRCE 2110
Query: 208 CGVGRVLRSDG----------------------------------------KTCEDVEGC 227
C G L G TCED++ C
Sbjct: 2111 CPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDEC 2170
Query: 228 HNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
N C+ C +E Y C CP G L ED C+
Sbjct: 2171 SLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR 2206
Score = 62.8 bits (151), Expect = 8e-10
Identities = 46/197 (23%), Positives = 68/197 (34%), Gaps = 61/197 (30%)
Query: 144 CGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE----- 195
C F +C HG+C +T C CA G L + C D +EC + C +
Sbjct: 990 CKVFPGLCT---HGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVN 1046
Query: 196 ---------------------------------------ICVNLKNSYRCECGVGRVLRS 216
C N SY+C+C G L +
Sbjct: 1047 TPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTA 1106
Query: 217 DGKTCEDVEGCHNNNGGCSH-SCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEV 275
G CED++ C ++G C H C+ +QC C G + D C +++
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC----------VDI 1156
Query: 276 NIPRELVGGLELFLTNT 292
N R GG ++ NT
Sbjct: 1157 NECRVQNGGCDVHCINT 1173
Score = 62.8 bits (151), Expect = 8e-10
Identities = 41/126 (32%), Positives = 53/126 (42%), Gaps = 15/126 (11%)
Query: 157 GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRV 213
G+C++ EC CA G G TC D +EC N C+ C N + SY C C G
Sbjct: 2139 GTCTNVIGGFECACADGFEPGL-MMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 214 LRSDGKTCEDVEGCHNNNGGC---SHSCLGSEKGYQCECPRGL--------VLSEDNHTC 262
LR DG C DV+ C + C C + C CP G+ ++DN
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 263 QVPVLC 268
P LC
Sbjct: 2258 AQPDLC 2263
Score = 62.8 bits (151), Expect = 8e-10
Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 2/111 (1%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC-SEICVNLKNSYRCECG 209
C C C+C G C DENEC + C S C N +RC C
Sbjct: 2538 CQHGCQNQLGGY-RCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCP 2596
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNH 260
G C++V+ C G CS+SC + G+ C CP+G + H
Sbjct: 2597 SGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGH 2647
Score = 62.0 bits (149), Expect = 1e-09
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 6/122 (4%)
Query: 144 CGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNL 200
C D+CD +G C + C C G D + C D +EC Q N C NL
Sbjct: 1366 CAENVDLCD---NGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENL 1422
Query: 201 KNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNH 260
+RC C G L G C D+ C + + C+ + Y C CP+ L+
Sbjct: 1423 PGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGV 1482
Query: 261 TC 262
C
Sbjct: 1483 GC 1484
Score = 61.6 bits (148), Expect = 2e-09
Identities = 40/125 (32%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 144 CGHFYDICDEDCHGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEI--CV 198
CG IC +G C + + C C G C D +EC C + C+
Sbjct: 1725 CGEIPAIC---ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCI 1781
Query: 199 NLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSE 257
N+ SYRC+C G L S G C C CSH C+ +E Y C C RG S
Sbjct: 1782 NIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASA 1840
Query: 258 DNHTC 262
D C
Sbjct: 1841 DQTLC 1845
Score = 59.3 bits (142), Expect = 9e-09
Identities = 52/180 (28%), Positives = 65/180 (36%), Gaps = 17/180 (9%)
Query: 94 LEGDGIVQRQA--CASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCF-HVYCGHF 147
LE DG + C S NC C+ CP G+ + CF + C
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHH----QACFDNDECSAQ 2492
Query: 148 YDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSY 204
C HG C +T C C G L C D NEC+ + C C N Y
Sbjct: 2493 PGPCG--AHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHR-CQHGCQNQLGGY 2549
Query: 205 RCECGVGRVLRSDGKTCEDVEGCHNNNGGC-SHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
RC C G S C D C + C S SC + G++C CP G + CQ
Sbjct: 2550 RCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Score = 58.5 bits (140), Expect = 1e-08
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 12/150 (8%)
Query: 131 YRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTC---APGTVLGPDRQTCFDENECE 187
+ +T+ C G ++ E C S + C APG + D +EC
Sbjct: 1667 FNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECG 1726
Query: 188 QNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS--CLGSEKG 244
+ C+ IC+N S+RCEC G S CEDV+ C + C + C+
Sbjct: 1727 EIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGS 1786
Query: 245 YQCECPRGLVLSED------NHTCQVPVLC 268
Y+C+C RG LS N ++P +C
Sbjct: 1787 YRCKCTRGYKLSPGGACVGRNECREIPNVC 1816
Score = 58.5 bits (140), Expect = 1e-08
Identities = 47/186 (25%), Positives = 64/186 (34%), Gaps = 54/186 (29%)
Query: 125 PGGYYV-----YRLTKPSVCF-HVYCGHFYDICDEDCHGSCSDTSE---CTCAPGTVLGP 175
PG Y Y+L+ C C ++C HG C DT C C G
Sbjct: 1784 PGSYRCKCTRGYKLSPGGACVGRNECREIPNVCS---HGDCMDTEGSYMCLCHRGFQASA 1840
Query: 176 DRQTCFDENECEQN---NGGCSEI------------------------------------ 196
D+ C D +EC++ NG C I
Sbjct: 1841 DQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRF 1900
Query: 197 --CVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGC-SHSCLGSEKGYQCECPRGL 253
C+N S+ C C G L +DGK C D C + G C +C E ++C CP G
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF 1960
Query: 254 VLSEDN 259
+ D+
Sbjct: 1961 QVQSDH 1966
Score = 53.9 bits (128), Expect = 4e-07
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 167 CAPGTVLGPDRQTCF--DENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCED 223
C G P+R T D +EC++ G C CVN S++CEC G L + CED
Sbjct: 1546 CPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICED 1605
Query: 224 VEGCHNNNGGCS-HSCLGSEKGYQCECPRGLVLSEDNHTC 262
++ C ++G C +C + Y C CP + + C
Sbjct: 1606 IDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNC 1645
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDV 224
C C PG +L P C D +EC+ + C N + S+RC+C G + +DG+ C D
Sbjct: 555 CLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Query: 225 ---EGCHN--NNGGCSHSCLGSEKGYQCEC 249
C+ G C+ G+ +C C
Sbjct: 615 HVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Score = 53.5 bits (127), Expect = 5e-07
Identities = 58/203 (28%), Positives = 83/203 (40%), Gaps = 22/203 (10%)
Query: 68 DAMPTFCIPENH--CGTHAPVWLNGSH---PLEGDGIVQRQACASFNGNCCLWNTTVEVK 122
+A PT P+ CG AP +L H PL+ D + A + NG C + +
Sbjct: 1689 EACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICA-NGICINQIGSFRCE 1747
Query: 123 ACPGGYYVYRLTKPSVCFHV-YCGHFYDICDE--DCHGSCSDTSECTCAPGTVLGPDRQT 179
CP G+ + C V CG C + DC + + C C G L P
Sbjct: 1748 -CPAGFNYNSILL--ACEDVDECGSRESPCQQNADCI-NIPGSYRCKCTRGYKLSPGG-A 1802
Query: 180 CFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHN---NNGGCS 235
C NEC + CS C++ + SY C C G +D C D++ C NG C
Sbjct: 1803 CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCK 1862
Query: 236 HSCLGSEKGYQCECPRGLVLSED 258
+ +GS Y C C G V++ +
Sbjct: 1863 -NIIGS---YNCLCFPGFVVTHN 1881
Score = 50.8 bits (120), Expect = 3e-06
Identities = 38/114 (33%), Positives = 46/114 (40%), Gaps = 8/114 (7%)
Query: 160 SDTSECTCAPGTVLGPDRQT---CFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLR 215
S C P G R T C D NECE G C CVN S+RCEC G +L
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 216 SDGKTCEDV--EGC--HNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVP 265
+ G+ C DV E C + C + G + C C G V + C P
Sbjct: 904 ASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDP 957
Score = 50.1 bits (118), Expect = 5e-06
Identities = 47/189 (24%), Positives = 70/189 (37%), Gaps = 22/189 (11%)
Query: 96 GDGIVQRQACASFN---GNCC----LWNTTVEVKACPGGYYVYRLTKPSVCFHVY--CGH 146
G G+ + C S GN C + NTT CPGG ++ + +V C
Sbjct: 1511 GVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEG-FQPNRITVILEDIDECQE 1569
Query: 147 FYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKN 202
+C G C +T +C C PG L + C D +EC ++G C C N
Sbjct: 1570 LPGLCQG---GDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLG 1626
Query: 203 SYRCECGVGRVLRSDGKTCEDVEGC---HNNNGGCSHSCLGSEKGYQCECPR--GLVLSE 257
+Y C C + + G C D+ + NG C + + C C G +
Sbjct: 1627 NYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNR 1686
Query: 258 DNHTCQVPV 266
C P+
Sbjct: 1687 PCEACPTPI 1695
Score = 46.6 bits (109), Expect = 6e-05
Identities = 62/262 (23%), Positives = 87/262 (33%), Gaps = 72/262 (27%)
Query: 46 QGPPLCDNHVNGE----WYHFTGMAGDAMPT--------FCIPENHC----GTHAPVWLN 89
QGP +C + + W F G + +P FC N C GT AP
Sbjct: 55 QGPNVCGSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAP---- 110
Query: 90 GSHPLEGDGIVQRQACA--SFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHF 147
G+ + C+ NG C + + C GY CG
Sbjct: 111 ------SCGVSRGSGCSVSCMNGGTCRGASCL----CQKGYT-----------GTVCGQ- 148
Query: 148 YDICDEDCH--GSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNG--GCSE-------- 195
ICD CH G C + C C G +GP + + C G GC
Sbjct: 149 -PICDRGCHNGGRCIGPNRCACVYG-FMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCT 206
Query: 196 ---ICVNLKNSYR--CE--------CGVGRVLRSDGKTCEDVEGCHNNNGGCSH-SCLGS 241
C + ++ CE C G + C+DV+ C G C SC+
Sbjct: 207 KALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNM 266
Query: 242 EKGYQCECPRGLVLSEDNHTCQ 263
+ C CP G LS+ + C+
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACE 288
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 182 DENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH-SCL 239
D NEC+ G C+ C N S+ C C G L + + C D++ C + C +C+
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 240 GSEKGYQCEC----PRGLVLSED----NHTCQVPVLCKSNA---IEVNIPRELVGGLELF 288
+ ++CEC G +L ++ + + P+LC+ + + + G EL
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 289 LTNTSCRGV 297
T+C +
Sbjct: 1106 AKGTACEDI 1114
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/216 (25%), Positives = 76/216 (35%), Gaps = 62/216 (28%)
Query: 95 EGDGIVQRQACASFNGNCCLWNTTVEVKA-----CPGGYYVYRLTKPSVCFHVYCGHFYD 149
+G V C S G C L T ++ CP G F V H D
Sbjct: 1923 DGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRCICPPG------------FQVQSDHCID 1969
Query: 150 I--CDEDCH----GSCSDTS---ECTCAPGTVLGPDRQTCFDENE----CEQNNGGCS-- 194
I C E+ + G+C+++ +C C PG VL + CFD + G CS
Sbjct: 1970 IDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 195 ------------------------EICVNLKNS---YRCECGVGRVLRSDGKTCEDVEGC 227
E+C ++ C G G V D EDV C
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSR-EDVNEC 2088
Query: 228 HNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTC 262
N G C++ C+ ++ ++CECP G L C
Sbjct: 2089 AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 5/91 (5%)
Query: 167 CAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVE 225
C G + C D +EC+ G C CVN+ S+ C C VG L CED
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 226 --GCHN--NNGGCSHSCLGSEKGYQCECPRG 252
C + G C+ G QC C RG
Sbjct: 292 AGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 28/137 (20%)
Query: 109 NGNCCLWN--TTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSEC- 165
NG+C ++ TT+ + C G+ + + FH C +++ + +C DT+EC
Sbjct: 1881 NGDCVDFDECTTLVGQVCRFGHCL----NTAGSFHCLCQDGFELTADG--KNCVDTNECL 1934
Query: 166 ----TCAPGT----------VLGPDRQT----CFDENECEQNNGGCS-EICVNLKNSYRC 206
TC PGT + P Q C D +EC + C C N S++C
Sbjct: 1935 SLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQC 1994
Query: 207 ECGVGRVLRSDGKTCED 223
C G VL +G C D
Sbjct: 1995 LCPPGFVLSDNGHRCFD 2011
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/112 (30%), Positives = 45/112 (40%), Gaps = 19/112 (16%)
Query: 124 CPGGYYVYRLTKPSVCFHVYCGHFYDIC---DEDCHG---SCSD---TSECTCAPGT-VL 173
CP GY + ++C V D C +DCH C + T C C PG L
Sbjct: 2192 CPAGYTLRE--DGAMCRDV------DECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 174 GPDRQTCFDENECEQNNGGC-SEICVNLKNSYRCECGVGRVLRSDGKTCEDV 224
+ C D+NEC C + CVN S+RC+C G C D+
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI 2295
Score = 39.3 bits (90), Expect = 0.009
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 197 CVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH-SCLGSEKGYQCECPRGLVL 255
C+ +SYRCEC VG G+ C DV+ C + C H C+ Y C C G
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRGE-CIDVDEC--TSSPCHHGDCVNIPGTYHCRCYPGFQA 480
Query: 256 SEDNHTC 262
+ C
Sbjct: 481 TPTRQAC 487
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/114 (25%), Positives = 40/114 (35%), Gaps = 13/114 (11%)
Query: 157 GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRV 213
GSC + C C G L C D NEC + +C+N SY C C
Sbjct: 1417 GSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFE 1476
Query: 214 LRSDGKTCEDVEGCHNNNGGC---SHSCLGSEKGYQCECPRGLVLSEDNHTCQV 264
L G C D G C +H + G C G+ ++ + C +
Sbjct: 1477 LNPSGVGCVDTRA-----GNCFLETHD--RGDSGISCSAEIGVGVTRASCCCSL 1523
Score = 38.9 bits (89), Expect = 0.012
Identities = 59/259 (22%), Positives = 87/259 (33%), Gaps = 65/259 (25%)
Query: 64 GMAGDAMPTFCIPENHCGTHAPVWLNGSH-----------PLEGDGIVQRQACASFN--- 109
G AGD FC + C + + NG + D +AC +
Sbjct: 1352 GFAGDGF--FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECA 1409
Query: 110 -GNCCLWNTTVEVKA-----CPGGYYVYR----------LTKPSVCFHVYC----GHFYD 149
GN C + + + C GGY + R P C + C G +
Sbjct: 1410 QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLC 1469
Query: 150 ICDEDCHGS-----CSDT--------------SECTCAPGTVLGPDRQTCFDENECEQNN 190
C +D + C DT S +C+ +G R +C C
Sbjct: 1470 SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCC----CSLGR 1525
Query: 191 --GGCSEICVNLKNS-YRCECGVGRVLRSDGKTC--EDVEGCHNNNGGCSHS-CLGSEKG 244
G E+C + YR C G + + T ED++ C G C C+ +
Sbjct: 1526 AWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGS 1585
Query: 245 YQCECPRGLVLSEDNHTCQ 263
+QCECP G LSE C+
Sbjct: 1586 FQCECPPGYHLSEHTRICE 1604
Score = 35.0 bits (79), Expect = 0.18
Identities = 56/258 (21%), Positives = 78/258 (30%), Gaps = 92/258 (35%)
Query: 68 DAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQAC------ASFNGNCCL-----WN 116
D TFC+ T WL +Q C AS CC W
Sbjct: 798 DPSGTFCLDS----TKGTCWLK----------IQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 117 TTVEV----KACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTS---ECTCAP 169
+ E AC G+ R+T + C F +C +G C +T+ C C
Sbjct: 844 SPCERCEIDPACARGFA--RMTGVTCDDVNECESFPGVCP---NGRCVNTAGSFRCECPE 898
Query: 170 GTVLGPDRQTC-----------FDENECEQNNGGCSEICVNLKNSYR---CECGVGRVLR 215
G +L + C +DE+EC V L YR C C +G V
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECG----------VTLPGKYRMDVCCCSIGAVWG 948
Query: 216 SDGKTC------------------------------EDVEGCHNNNGGCSH-SCLGSEKG 244
+ + C +DV C G C+H +C +
Sbjct: 949 VECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGS 1008
Query: 245 YQCECPRGLVLSEDNHTC 262
+ C C G L C
Sbjct: 1009 FHCACAGGFALDAQERNC 1026
>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
sapiens]
Length = 1207
Score = 95.1 bits (235), Expect = 1e-19
Identities = 49/114 (42%), Positives = 56/114 (49%), Gaps = 8/114 (7%)
Query: 157 GSCSDT--------SECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCEC 208
G+CS T C CA G L DR+ C D NEC N GC+ C N SY C C
Sbjct: 323 GNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTC 382
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
VG VL DGK C + C N CSH C+ + +G C CP G VL D TC
Sbjct: 383 PVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTC 436
Score = 65.5 bits (158), Expect = 1e-10
Identities = 34/94 (36%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 182 DENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLG 240
++ C+ G CS +C S+ C C G L D K CEDV C N GC+ C
Sbjct: 314 EQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKN 373
Query: 241 SEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIE 274
+ Y C CP G VL D C V C N E
Sbjct: 374 TPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSE 407
Score = 57.0 bits (136), Expect = 4e-08
Identities = 45/131 (34%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 102 RQACASFNGNCCLWN--TTVEVKACPGGYYV------YRLTKPSVCFH-VYCGHFYDICD 152
R+ C N C WN T+ K PG YY L C V C C
Sbjct: 351 RKYCEDVN-ECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECS 409
Query: 153 EDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQ-NNGGCSEICVNLKN-SYRCECGV 210
DC + S+ C C G+VL D +TC + C +NGGCS++CV L S+ C+C
Sbjct: 410 HDCVLT-SEGPLCFCPEGSVLERDGKTC---SGCSSPDNGGCSQLCVPLSPVSWECDCFP 465
Query: 211 GRVLRSDGKTC 221
G L+ D K+C
Sbjct: 466 GYDLQLDEKSC 476
Score = 53.1 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 161 DTSECTCAPGTVLGPDRQTCFDENECEQNNGGC---SEICVNLKNSYRCECGVGRVLRSD 217
+ + C C G D + C D +ECE C S C+N + Y C C G + D
Sbjct: 851 EDATCQCLKG--FAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEG--YQGD 906
Query: 218 GKTCEDVEGCHNNNGGCSH--SCLGSEKGYQCEC 249
G C D++ C C SC +E GY C C
Sbjct: 907 GIHCLDIDECQLGEHSCGENASCTNTEGGYTCMC 940
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 182 DENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGC---SHSC 238
D+++C C++ C+C G DGK C D++ C C S C
Sbjct: 831 DQDDCAPVGCSMYARCISEGEDATCQCLKG--FAGDGKLCSDIDECEMGVPVCPPASSKC 888
Query: 239 LGSEKGYQCECPRG 252
+ +E GY C C G
Sbjct: 889 INTEGGYVCRCSEG 902
Score = 39.3 bits (90), Expect = 0.009
Identities = 19/48 (39%), Positives = 23/48 (47%)
Query: 186 CEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGG 233
C NGGC IC + C C G + SDGKTC ++G GG
Sbjct: 745 CLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGG 792
Score = 32.0 bits (71), Expect = 1.5
Identities = 13/36 (36%), Positives = 15/36 (41%)
Query: 227 CHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C NGGC H C C C G + + D TC
Sbjct: 745 CLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC 780
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 6/61 (9%)
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNNGGCSE--ICVNLKNSYRCECGVGRVLRSDGKTCE 222
C C+ G D C D +EC+ C E C N + Y C C GR L G C
Sbjct: 897 CRCSEG--YQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMC-AGR-LSEPGLICP 952
Query: 223 D 223
D
Sbjct: 953 D 953
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 94.7 bits (234), Expect = 2e-19
Identities = 43/110 (39%), Positives = 60/110 (54%), Gaps = 2/110 (1%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGV 210
CD CH + + CTC G +L PDR+TC D +EC NNGGC IC N S+ C C
Sbjct: 247 CDSKCHDAATGV-HCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKK 305
Query: 211 GRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNH 260
G L + + C+D++ C + + C H C+ + +QC C RG +L H
Sbjct: 306 GYKLLINERNCQDIDEC-SFDRTCDHICVNTPGSFQCLCHRGYLLYGITH 354
Score = 92.8 bits (229), Expect = 7e-19
Identities = 46/116 (39%), Positives = 61/116 (52%), Gaps = 8/116 (6%)
Query: 153 EDCH--GSCSDTS---ECTCAPGTVLGPDRQTCFDENECE-QNNGGCSEICVNLKNSYRC 206
++CH C +T +C C G D + C D +ECE ++N GC CVN+ +YRC
Sbjct: 38 DNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVHDCVNIPGNYRC 95
Query: 207 ECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C G L DG C DV+ C NGGC SC+ Y+C C G LS++ HTC
Sbjct: 96 TCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 91.3 bits (225), Expect = 2e-18
Identities = 42/112 (37%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Query: 155 CHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
C +C DT + C C VL D +TC + C NNGGC C + C C VG
Sbjct: 208 CQHTCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDSKCHDAATGVHCTCPVG 265
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
+L+ D KTC+D++ C NNGGC H C + ++C C +G L + CQ
Sbjct: 266 FMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQ 317
Score = 87.4 bits (215), Expect = 3e-17
Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGV 210
C DC + CTC G L D C D +EC + NGGC + CVN+ SY C C
Sbjct: 82 CVHDCV-NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCRE 140
Query: 211 GRVLRSDGKTC----EDVEGCHNNNGGCSHSCLGSEK-GYQCECPRGLVLSEDNHTCQV 264
G L + TC E+ C N N GC+H C + K G CEC G L+++ C++
Sbjct: 141 GFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKL 199
Score = 87.0 bits (214), Expect = 4e-17
Identities = 52/144 (36%), Positives = 68/144 (47%), Gaps = 12/144 (8%)
Query: 144 CGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNS 203
C H IC E G + C C PG L +++ C + C NGGC C + +
Sbjct: 168 CAH---ICRETPKGGIA----CECRPGFELTKNQRDC--KLTCNYGNGGCQHTCDDTEQG 218
Query: 204 YRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
RC C + VL +DGKTC +E C NNGGC C + G C CP G +L D TC+
Sbjct: 219 PRCGCHIKFVLHTDGKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCK 276
Query: 264 VPVLCK-SNAIEVNIPRELVGGLE 286
C+ +N +I R VG E
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFE 300
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 92.0 bits (227), Expect = 1e-18
Identities = 43/116 (37%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Query: 148 YDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCE 207
Y C + C + + CTC PG L D ++C D NEC N C + CVN S+ C
Sbjct: 174 YGYCQQLC-ANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENP-CVQTCVNTYGSFICR 231
Query: 208 CGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
C G L DG C D++ C + C H C+ Y C CP G +L +DN +CQ
Sbjct: 232 CDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQ 287
Score = 65.5 bits (158), Expect = 1e-10
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 28/186 (15%)
Query: 105 CASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSE 164
C+ +G L +++ C GY + C + + ++ SC D +E
Sbjct: 153 CSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDG--RSCQDVNE 210
Query: 165 CT-------------------CAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYR 205
C C PG L D C D +EC + C CVN +Y
Sbjct: 211 CATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYF 270
Query: 206 CECGVGRVLRSDGKTCEDVEGCHNNNGGCS--HSCLGSEKGYQC----ECPRGLVLSEDN 259
C C G +L D ++C+D+ C + N C+ +C + G++C C + DN
Sbjct: 271 CSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDN 330
Query: 260 HTCQVP 265
C P
Sbjct: 331 R-CMCP 335
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 180 CFDENECEQNNGGCS--EICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS 237
C D +EC ++ C+ +IC+N + Y C C G L C D++ C G C
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG--QCLDIDEC--RYGYCQQL 180
Query: 238 CLGSEKGYQCECPRGLVLSEDNHTCQ 263
C Y C C G L+ED +CQ
Sbjct: 181 CANVPGSYSCTCNPGFTLNEDGRSCQ 206
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 91.7 bits (226), Expect = 2e-18
Identities = 71/270 (26%), Positives = 111/270 (41%), Gaps = 20/270 (7%)
Query: 266 VLCKSNAIEVNIPRELVGGLELFLTNT---------SCRGVSNGTHVNILFSLKTCGTVV 316
+LC N ++ ++ R + L ++ CR V CGT
Sbjct: 1374 LLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFK 1433
Query: 317 DVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPN----L 372
ND I SN +T SG I R + L I V+C + + Y+ N +
Sbjct: 1434 QADNDTIDYSNFLTA------AVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHV 1487
Query: 373 RNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESL 432
N+ +++ +G F + + + F P + L LY E + + L
Sbjct: 1488 ANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLF 1547
Query: 433 VESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVF 492
V++C A+P S L Y LIR GCV DD+ Y+S F+ F F+ + V+
Sbjct: 1548 VDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNR-FPSVY 1606
Query: 493 LHCRVLVCGVLDERSRCAQGCHRRMRRGAG 522
L C+++VC D SRC +GC R +R G
Sbjct: 1607 LRCKMVVCRAYDPSSRCYRGCVLRSKRDVG 1636
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 91.7 bits (226), Expect = 2e-18
Identities = 71/270 (26%), Positives = 111/270 (41%), Gaps = 20/270 (7%)
Query: 266 VLCKSNAIEVNIPRELVGGLELFLTNT---------SCRGVSNGTHVNILFSLKTCGTVV 316
+LC N ++ ++ R + L ++ CR V CGT
Sbjct: 1500 LLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFK 1559
Query: 317 DVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPN----L 372
ND I SN +T SG I R + L I V+C + + Y+ N +
Sbjct: 1560 QADNDTIDYSNFLTA------AVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHV 1613
Query: 373 RNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESL 432
N+ +++ +G F + + + F P + L LY E + + L
Sbjct: 1614 ANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLF 1673
Query: 433 VESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVF 492
V++C A+P S L Y LIR GCV DD+ Y+S F+ F F+ + V+
Sbjct: 1674 VDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNR-FPSVY 1732
Query: 493 LHCRVLVCGVLDERSRCAQGCHRRMRRGAG 522
L C+++VC D SRC +GC R +R G
Sbjct: 1733 LRCKMVVCRAYDPSSRCYRGCVLRSKRDVG 1762
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 91.7 bits (226), Expect = 2e-18
Identities = 71/270 (26%), Positives = 111/270 (41%), Gaps = 20/270 (7%)
Query: 266 VLCKSNAIEVNIPRELVGGLELFLTNT---------SCRGVSNGTHVNILFSLKTCGTVV 316
+LC N ++ ++ R + L ++ CR V CGT
Sbjct: 2115 LLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFK 2174
Query: 317 DVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPN----L 372
ND I SN +T SG I R + L I V+C + + Y+ N +
Sbjct: 2175 QADNDTIDYSNFLTA------AVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHV 2228
Query: 373 RNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESL 432
N+ +++ +G F + + + F P + L LY E + + L
Sbjct: 2229 ANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLF 2288
Query: 433 VESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVF 492
V++C A+P S L Y LIR GCV DD+ Y+S F+ F F+ + V+
Sbjct: 2289 VDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNR-FPSVY 2347
Query: 493 LHCRVLVCGVLDERSRCAQGCHRRMRRGAG 522
L C+++VC D SRC +GC R +R G
Sbjct: 2348 LRCKMVVCRAYDPSSRCYRGCVLRSKRDVG 2377
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 91.7 bits (226), Expect = 2e-18
Identities = 71/270 (26%), Positives = 111/270 (41%), Gaps = 20/270 (7%)
Query: 266 VLCKSNAIEVNIPRELVGGLELFLTNT---------SCRGVSNGTHVNILFSLKTCGTVV 316
+LC N ++ ++ R + L ++ CR V CGT
Sbjct: 2125 LLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFK 2184
Query: 317 DVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPN----L 372
ND I SN +T SG I R + L I V+C + + Y+ N +
Sbjct: 2185 QADNDTIDYSNFLTA------AVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHV 2238
Query: 373 RNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESL 432
N+ +++ +G F + + + F P + L LY E + + L
Sbjct: 2239 ANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLF 2298
Query: 433 VESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVF 492
V++C A+P S L Y LIR GCV DD+ Y+S F+ F F+ + V+
Sbjct: 2299 VDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNR-FPSVY 2357
Query: 493 LHCRVLVCGVLDERSRCAQGCHRRMRRGAG 522
L C+++VC D SRC +GC R +R G
Sbjct: 2358 LRCKMVVCRAYDPSSRCYRGCVLRSKRDVG 2387
>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
[Homo sapiens]
Length = 1785
Score = 91.7 bits (226), Expect = 2e-18
Identities = 71/270 (26%), Positives = 111/270 (41%), Gaps = 20/270 (7%)
Query: 266 VLCKSNAIEVNIPRELVGGLELFLTNT---------SCRGVSNGTHVNILFSLKTCGTVV 316
+LC N ++ ++ R + L ++ CR V CGT
Sbjct: 1497 LLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFK 1556
Query: 317 DVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPN----L 372
ND I SN +T SG I R + L I V+C + + Y+ N +
Sbjct: 1557 QADNDTIDYSNFLTA------AVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHV 1610
Query: 373 RNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESL 432
N+ +++ +G F + + + F P + L LY E + + L
Sbjct: 1611 ANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLF 1670
Query: 433 VESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVF 492
V++C A+P S L Y LIR GCV DD+ Y+S F+ F F+ + V+
Sbjct: 1671 VDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNR-FPSVY 1729
Query: 493 LHCRVLVCGVLDERSRCAQGCHRRMRRGAG 522
L C+++VC D SRC +GC R +R G
Sbjct: 1730 LRCKMVVCRAYDPSSRCYRGCVLRSKRDVG 1759
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 91.7 bits (226), Expect = 2e-18
Identities = 43/111 (38%), Positives = 56/111 (50%), Gaps = 4/111 (3%)
Query: 155 CHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
C CS TS CTC G L D++TC D ++C ++ C ++C N Y C C G
Sbjct: 342 CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAG 400
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
L +DG CEDV+ C ++ GGC H C +QC C G L ED C
Sbjct: 401 YRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 90.1 bits (222), Expect = 5e-18
Identities = 52/176 (29%), Positives = 72/176 (40%), Gaps = 6/176 (3%)
Query: 105 CASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHVY-CGHFYDICDEDCHGSCS 160
C + NG C C+ + C G+ ++ T C + C C C
Sbjct: 165 CRTHNGGCQHRCVNTPGSYLCECKPGFRLH--TDSRTCLAINSCALGNGGCQHHCVQLTI 222
Query: 161 DTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKT 220
C C PG L D + C + C NG C C ++ RCEC VG L +DGK
Sbjct: 223 TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKA 282
Query: 221 CEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVN 276
CEDV+ C C+H CL ++ ++C C G L D C + N+ E N
Sbjct: 283 CEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAN 338
Score = 88.2 bits (217), Expect = 2e-17
Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 5/105 (4%)
Query: 163 SECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTC- 221
+ C C G L D + C D +EC C+ C+N + S++C C G L +DG+ C
Sbjct: 266 ARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCY 325
Query: 222 ----EDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
E V C NNGGCSH C + G C CPRG L D TC
Sbjct: 326 RIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC 370
Score = 83.2 bits (204), Expect = 6e-16
Identities = 47/129 (36%), Positives = 59/129 (45%), Gaps = 20/129 (15%)
Query: 137 SVCFHVYCGHFYDICDEDCHGSC--SDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCS 194
S+CFH G C C C PG GP Q +D +EC +NGGC
Sbjct: 131 SLCFH--------------GGRCVPGSAQPCHCPPG-FQGPRCQ--YDVDECRTHNGGCQ 173
Query: 195 EICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLG-SEKGYQCECPRGL 253
CVN SY CEC G L +D +TC + C NGGC H C+ + ++C+C G
Sbjct: 174 HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF 233
Query: 254 VLSEDNHTC 262
L ED C
Sbjct: 234 QLQEDGRHC 242
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 16/130 (12%)
Query: 104 ACASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDED--CHGS 158
+C + NG C C + + CP GY + T C V D C + C
Sbjct: 334 SCEANNGGCSHGCSHTSAGPLCTCPRGYELD--TDQRTCIDV------DDCADSPCCQQV 385
Query: 159 CSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLR 215
C++ EC C G L D C D +EC + GGC C NL S++C C G L
Sbjct: 386 CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLH 445
Query: 216 SDGKTCEDVE 225
D + C +E
Sbjct: 446 EDRRGCSPLE 455
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/187 (27%), Positives = 68/187 (36%), Gaps = 47/187 (25%)
Query: 104 ACASFNGNCCLWNTTVEVKACPGGYYVYRLTK--PSVCFHVYCGHFYDICDEDCHGSCSD 161
AC S +G C K CP G+ + P F V C CHG
Sbjct: 706 ACDSVSGECG--------KRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV--- 754
Query: 162 TSECTCAPGTVLGPDRQTCFDENECEQNNGG--CSEICVNLKNSYRCECGVGRVLRSD-- 217
T +C C PG G D C E +C + G C EIC +++ RC+ G L
Sbjct: 755 TGQCRCPPGRT-GED---C--EADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGF 808
Query: 218 -GKTCEDV------------------EG-CHNNNGGCSHSCLGSEKGYQCE--CPRGLVL 255
G C+DV +G CH G C SC G+ C+ C G
Sbjct: 809 VGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHC--SCAPGWTGFSCQRACDTGHWG 866
Query: 256 SEDNHTC 262
+ +H C
Sbjct: 867 PDCSHPC 873
Score = 37.7 bits (86), Expect = 0.027
Identities = 48/185 (25%), Positives = 63/185 (34%), Gaps = 29/185 (15%)
Query: 103 QACASFNGNCC-----------LWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDIC 151
QACA FNG C W ++ACP G Y +C + G D
Sbjct: 1001 QACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQN---GGTCDPV 1057
Query: 152 DEDC---HGSCSDTSECTCAPGTVLGPDRQT--CFDENECEQNNGGCSEICVNLKNSYRC 206
C G E C P V R + C + C+ + G C +C +C
Sbjct: 1058 SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRC--LCPAGWTGDKC 1115
Query: 207 E--CGVGRVLRSDGKTCEDVEG--CHNNNGGCSHSCLGSEKGYQCE--CPRGLVLSEDNH 260
+ C G + + C G CH+ G C C G CE CP G +
Sbjct: 1116 QSPCLRGWFGEACAQRCSCPPGAACHHVTGAC--RCPPGFTGSGCEQACPPGSFGEDCAQ 1173
Query: 261 TCQVP 265
CQ P
Sbjct: 1174 MCQCP 1178
Score = 37.7 bits (86), Expect = 0.027
Identities = 47/175 (26%), Positives = 57/175 (32%), Gaps = 42/175 (24%)
Query: 103 QACASFNGNCCLWNTTVEVKACPGGYYVY--RLTKPSVCFHVYCGHFYDICDEDCHGSCS 160
Q C NG C + CP G+ LT P F C H +C +C
Sbjct: 1217 QLCGCLNGGSC--DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH---VCGCGQGAACD 1271
Query: 161 D-TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGK 219
T C C PG R E C QN G C + C C G +
Sbjct: 1272 PVTGTCLCPPG------RAGVRCERGCPQNRFGVG--C-----EHTCSCRNGGL------ 1312
Query: 220 TCEDVEGCHNNNGGCSHSCLGSEKGYQCE--CPRGLVLSEDNHTCQVPVLCKSNA 272
CH +NG C SC G CE CP G C + C +N+
Sbjct: 1313 -------CHASNGSC--SCGLGWTGRHCELACPPG----RYGAACHLECSCHNNS 1354
Score = 29.3 bits (64), Expect = 9.7
Identities = 43/167 (25%), Positives = 52/167 (31%), Gaps = 45/167 (26%)
Query: 105 CASFNGNCCL---WNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSD 161
C + NG+C W ACP G Y CH CS
Sbjct: 1313 CHASNGSCSCGLGWTGRHCELACPPGRY----------------------GAACHLECSC 1350
Query: 162 TSECTCAPGT---VLGPDRQTCFDENECEQ--NNGGCSEICVNLKN------SYRCECGV 210
+ TC P T GP E+ C + GC +C S RC C
Sbjct: 1351 HNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPA 1410
Query: 211 GRVLRSDGKTCEDVEGCHNNN--GGCSHSCLGSEKGYQCECPRGLVL 255
G G CE GC + GC C + G C+ GL L
Sbjct: 1411 G----FHGHFCE--RGCEPGSFGEGCHQRC-DCDGGAPCDPVTGLCL 1450
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 91.3 bits (225), Expect = 2e-18
Identities = 53/161 (32%), Positives = 73/161 (45%), Gaps = 14/161 (8%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGR 212
+G C +T C C G +C D +EC Q+ C+ IC N + SY+C C G
Sbjct: 2462 NGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGY 2521
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSE----DNHTC-QVPVL 267
VL+ DGKTC+D++ C C C+ + G+ C+CP G DN+ C P L
Sbjct: 2522 VLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSL 2581
Query: 268 CKSNAIEVNIPR----ELVGGLELFLTNTSCRGVS--NGTH 302
C + I N P E G L T +C V +G H
Sbjct: 2582 CGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNH 2622
Score = 90.5 bits (223), Expect = 4e-18
Identities = 44/111 (39%), Positives = 56/111 (50%), Gaps = 4/111 (3%)
Query: 156 HGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGR 212
+G C + T +C+C PG PDRQ C D +EC NGGC C N + SY C C G
Sbjct: 1213 NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGY 1272
Query: 213 VLRSDGKTCEDVEGCHNNNGGC-SHSCLGSEKGYQCECPRGLVLSEDNHTC 262
L DG++C D++ C NN C C Y+C C G + S D TC
Sbjct: 1273 ALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 1323
Score = 88.2 bits (217), Expect = 2e-17
Identities = 42/119 (35%), Positives = 58/119 (48%), Gaps = 4/119 (3%)
Query: 157 GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGR 212
G+C +T +C C G L P R+ C D NEC ++ C CVN+ +Y+C C G
Sbjct: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY 1231
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
D + C D++ C NGGC C SE Y+C C G L D +C C++N
Sbjct: 1232 QATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENN 1290
Score = 78.6 bits (192), Expect = 1e-14
Identities = 60/210 (28%), Positives = 89/210 (42%), Gaps = 37/210 (17%)
Query: 80 CGTHAPVWLNG-------SHPLEGDGIVQRQACASFNGNC-----CLWN--TTVEVKACP 125
C HA + LNG S+ E + ++ A NG+C C N T + P
Sbjct: 498 CKHHANLCLNGRCIPTVSSYRCECNMGYKQDA----NGDCIDVDECTSNPCTNGDCVNTP 553
Query: 126 GGYYV------YRLTKPSVCFHVYCGHFYDICDED---C-HGSCSDTS---ECTCAPGTV 172
G YY R C + D C ++ C +G C +T +C C G
Sbjct: 554 GSYYCKCHAGFQRTPTKQACIDI------DECIQNGVLCKNGRCVNTDGSFQCICNAGFE 607
Query: 173 LGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNG 232
L D + C D +EC N + +C+N S++C C G VL +G+ C DV+ C
Sbjct: 608 LTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGI 667
Query: 233 GCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
+ C+ SE ++C+CP GL + D C
Sbjct: 668 CMNGHCINSEGSFRCDCPPGLAVGMDGRVC 697
Score = 78.2 bits (191), Expect = 2e-14
Identities = 54/169 (31%), Positives = 77/169 (45%), Gaps = 18/169 (10%)
Query: 101 QRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHV-YCGHFY-DICDEDCHGS 158
+R C NG C + PG + LT + C + C F+ +C +G
Sbjct: 1939 ERHPCG--NGTCKNTVGSYNCLCYPG----FELTHNNDCLDIDECSSFFGQVCR---NGR 1989
Query: 159 CSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVL 214
C + + +C C G L PD + C D NEC G CS C NL+ S+RC C G +
Sbjct: 1990 CFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEV 2049
Query: 215 RSDGKTCEDVEGCHNNNGGCSH-SCLGSEKGYQCECPRGLVLSEDNHTC 262
+S+ C D+ C + C SC + G+QC CP G VLS++ C
Sbjct: 2050 KSEN--CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC 2096
Score = 76.3 bits (186), Expect = 7e-14
Identities = 44/142 (30%), Positives = 59/142 (41%), Gaps = 26/142 (18%)
Query: 153 EDCHGSCSDTSECT-------------------CAPGTVLGPDRQTCFDENECEQNNGGC 193
+D +G C D ECT C G P +Q C D +EC QN C
Sbjct: 527 QDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLC 586
Query: 194 SE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
CVN S++C C G L +DGK C D + C N + C+ + ++C C G
Sbjct: 587 KNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
Query: 253 LVLS------EDNHTCQVPVLC 268
VL+ D CQ P +C
Sbjct: 647 FVLAPNGRYCTDVDECQTPGIC 668
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/171 (31%), Positives = 72/171 (42%), Gaps = 28/171 (16%)
Query: 109 NGNCCLWNTTVEVKA-----CPGGYYVYRLTKPSVCFHVYCGHFYDICDE-----DCHGS 158
N N C++ K C GY V + T + C V D C+ D H S
Sbjct: 1332 NSNICMFGECENTKGSFICHCQLGYSVKKGT--TGCTDV------DECEIGAHNCDMHAS 1383
Query: 159 CSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCS--EICVNLKNSYRCECGVGRV 213
C + + +C+C G + + C D +EC CS CVN SYRC C G
Sbjct: 1384 CLNIPGSFKCSCREGWIGNGIK--CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEG-- 1439
Query: 214 LRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQ 263
DG TC DV+ C N C + CL Y+CEC G + D+ +CQ
Sbjct: 1440 FTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 1490
Score = 71.2 bits (173), Expect = 2e-12
Identities = 45/137 (32%), Positives = 63/137 (45%), Gaps = 10/137 (7%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECG 209
CD C S + EC+C+ G L PD ++C D +ECE N C C N+ YRC C
Sbjct: 1253 CDTQCTNS-EGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCY 1311
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSH-SCLGSEKGYQCECPRGLVLSE------DNHTC 262
G + D KTC DV C N+ C C ++ + C C G + + D C
Sbjct: 1312 DGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDEC 1371
Query: 263 QVPV-LCKSNAIEVNIP 278
++ C +A +NIP
Sbjct: 1372 EIGAHNCDMHASCLNIP 1388
Score = 70.5 bits (171), Expect = 4e-12
Identities = 36/109 (33%), Positives = 45/109 (41%), Gaps = 5/109 (4%)
Query: 149 DICDED--CHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNS 203
D CD + C C + C C G + C DENEC N S C N S
Sbjct: 2616 DECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGS 2675
Query: 204 YRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
Y+C C G C DV C ++ C++ C +E GY C CP G
Sbjct: 2676 YKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPG 2724
Score = 68.9 bits (167), Expect = 1e-11
Identities = 38/113 (33%), Positives = 51/113 (45%), Gaps = 7/113 (6%)
Query: 156 HGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGR 212
+G+C++ + EC C G GP C D NEC QN C+ C+N SY C C +G
Sbjct: 2225 NGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGY 2283
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSH---SCLGSEKGYQCECPRGLVLSEDNHTC 262
LR D K C+D++ C C C + C CP G+ D C
Sbjct: 2284 ALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC 2336
Score = 67.4 bits (163), Expect = 3e-11
Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 21/230 (9%)
Query: 99 IVQRQACASFNGNCCLWNTTVEVKACPG--GYYVYRLTKPSVCFHVYCGHFYDICD-EDC 155
+ +R C ++N WN E PG + P F ++ G DI + ++
Sbjct: 1757 VTKRMCCCTYNVGKA-WNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEI 1815
Query: 156 HGSCSD--------TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEI--CVNLKNSYR 205
G C++ + C C G C D +EC + C C+N SYR
Sbjct: 1816 PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
Query: 206 CECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQV 264
CEC G L +G C D C CSH C+ + YQC C G S+D C
Sbjct: 1876 CECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD 1934
Query: 265 PVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNGTHVNILFSLKTCGT 314
C+ + + VG N C TH N + C +
Sbjct: 1935 VDECERHPCGNGTCKNTVGSY-----NCLCYPGFELTHNNDCLDIDECSS 1979
Score = 66.2 bits (160), Expect = 7e-11
Identities = 40/118 (33%), Positives = 53/118 (44%), Gaps = 8/118 (6%)
Query: 149 DICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCE 207
DIC + + C C G + C D +EC N C +C N SY C
Sbjct: 777 DICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCT 836
Query: 208 CGVGRVLRSDGKTCEDVEGCHNN---NGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C G V R++ +TCED+ C +N NG C ++ LGS + CEC G LS C
Sbjct: 837 CPPGYVFRTETETCEDINECESNPCVNGACRNN-LGS---FNCECSPGSKLSSTGLIC 890
Score = 65.5 bits (158), Expect = 1e-10
Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 15/128 (11%)
Query: 144 CGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGC-SEICVN 199
C F +C +G C +T +C C G L + + C D +EC + C S ICVN
Sbjct: 1077 CKAFPGMCT---YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVN 1133
Query: 200 LKNSYRCECGVGRVLRSDG----KTCEDVEGCHNNNGGC-SHSCLGSEKGYQCECPRGLV 254
S+ CEC G G K C D++ C N C +C+ +E +QC+CP G
Sbjct: 1134 TPGSFECECFEG---YESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 1190
Query: 255 LSEDNHTC 262
LS C
Sbjct: 1191 LSPSREDC 1198
Score = 65.5 bits (158), Expect = 1e-10
Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 7/115 (6%)
Query: 155 CHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE---ICVNLKNSYRCEC 208
C C +T ECTC G L D++ C D +EC + C +C NL ++ C C
Sbjct: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2323
Query: 209 GVGRVLRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTC 262
G R DG+ C D C G C + C+ Y+CEC G S C
Sbjct: 2324 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC 2378
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/131 (29%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 144 CGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNL 200
CG +C G C +T C C G L C D +EC+ N+ C C N+
Sbjct: 2575 CGSQPSLCG--AKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHR-CQHGCQNI 2631
Query: 201 KNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNH 260
YRC C G + C D C N N S SC + Y+C CP G + +
Sbjct: 2632 LGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSS 2691
Query: 261 TCQVPVLCKSN 271
C C S+
Sbjct: 2692 ACHDVNECSSS 2702
Score = 64.7 bits (156), Expect = 2e-10
Identities = 53/151 (35%), Positives = 65/151 (43%), Gaps = 36/151 (23%)
Query: 150 ICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQN---NGGCSEICVNLKNSYRC 206
+CD + + CTC PG V + +TC D NECE N NG C N S+ C
Sbjct: 820 LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACR----NNLGSFNC 875
Query: 207 ECGVGRVLRSDGKTCED-VEG----------CHNNNGGC---SHSC--LGSEKGYQCE-- 248
EC G L S G C D ++G C N G S C LG+ G CE
Sbjct: 876 ECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERC 935
Query: 249 -----CPRGL-----VLSEDNHTCQV-PVLC 268
CPRGL V ED + C+V P +C
Sbjct: 936 ELDTACPRGLARIKGVTCEDVNECEVFPGVC 966
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/149 (27%), Positives = 64/149 (42%), Gaps = 11/149 (7%)
Query: 131 YRLTKPSVCFHVYCGHFYDICDEDCH--GSCSDTSECTCAPGTVLGPDRQTCFDENECEQ 188
+ +TK C G ++ E C G+ + C PG D +EC++
Sbjct: 1755 FNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKE 1814
Query: 189 NNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS--CLGSEKGY 245
G C+ +C+N S+RCEC G CED++ C N + C + C+ S Y
Sbjct: 1815 IPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSY 1874
Query: 246 QCECPRGLVLS------EDNHTCQVPVLC 268
+CEC G LS + N ++P +C
Sbjct: 1875 RCECAAGFKLSPNGACVDRNECLEIPNVC 1903
Score = 64.3 bits (155), Expect = 3e-10
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
Query: 167 CAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVE 225
C+ G + D + D NEC + C+ IC NL+ SYRC C G + G+ C D++
Sbjct: 756 CSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDID 812
Query: 226 GCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
C N C + C + Y C CP G V + TC+ C+SN
Sbjct: 813 ECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESN 859
Score = 62.8 bits (151), Expect = 8e-10
Identities = 56/198 (28%), Positives = 74/198 (37%), Gaps = 35/198 (17%)
Query: 96 GDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYR---LTKPSVCFHVYC----GHFY 148
GD + QR A + K P G V R L P+VC H C G +
Sbjct: 1857 GDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQ 1916
Query: 149 DICD---------------EDC------HGSCSDTS---ECTCAPGTVLGPDRQTCFDEN 184
IC ++C +G+C +T C C PG L + C D +
Sbjct: 1917 CICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNND-CLDID 1975
Query: 185 ECEQNNGGCSEI--CVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCS-HSCLGS 241
EC G C N S++C C G L DGK C D C G CS +C
Sbjct: 1976 ECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNL 2035
Query: 242 EKGYQCECPRGLVLSEDN 259
E ++C CP G + +N
Sbjct: 2036 EGSFRCICPPGYEVKSEN 2053
Score = 62.8 bits (151), Expect = 8e-10
Identities = 34/111 (30%), Positives = 46/111 (41%), Gaps = 4/111 (3%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGR 212
+G C +T C C G L C D +EC N + C N+ S+ C C G
Sbjct: 2184 NGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEG- 2242
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
CED+ C N C+ C+ + Y+C CP G L ED C+
Sbjct: 2243 FEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCK 2293
Score = 60.1 bits (144), Expect = 5e-09
Identities = 38/130 (29%), Positives = 50/130 (38%), Gaps = 23/130 (17%)
Query: 157 GSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRS 216
G+C D EC PG C+ N C+N S+ C C G
Sbjct: 272 GACQDVDECQAIPGI--------------CQGGN------CINTVGSFECRCPAGHKQSE 311
Query: 217 DGKTCEDVEGCHNNNGGC-SHSCLGSEKGYQCECPRGLVLSEDNHTC--QVPVLCKSNAI 273
+ CED++ C G C + C + Y C CPRG V S D C Q +C S +
Sbjct: 312 TTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLV 371
Query: 274 EVNIPRELVG 283
+EL G
Sbjct: 372 NGRCAQELPG 381
Score = 59.3 bits (142), Expect = 9e-09
Identities = 32/74 (43%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 162 TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKT 220
T C C PG PD + C DENEC G C CVN+ SYRCEC G S G
Sbjct: 2318 TFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTE 2377
Query: 221 CEDVEGCHNNNGGC 234
C D N G C
Sbjct: 2378 CLD-----NRQGLC 2386
Score = 56.2 bits (134), Expect = 7e-08
Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 149 DICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCE 207
++C +D + D C GTV T D NEC ++ G CS C+N S+RCE
Sbjct: 2141 ELCPKDDEVAFQDL--CPYGHGTVPSL-HDTREDVNECLESPGICSNGQCINTDGSFRCE 2197
Query: 208 CGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG-----LVLSEDNHTC 262
C +G L G C D + C N + +C ++C C G ++ ED + C
Sbjct: 2198 CPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINEC 2257
Query: 263 -QVPVLC 268
Q P+LC
Sbjct: 2258 AQNPLLC 2264
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 164 ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCED 223
+C C PG VL P+ + C D +EC+ + C+N + S+RC+C G + DG+ C D
Sbjct: 640 KCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVD 699
Query: 224 V---EGCHN--NNGGCSHSCLGSEKGYQCEC 249
C+ G C G+ +C C
Sbjct: 700 THMRSTCYGGIKKGVCVRPFPGAVTKSECCC 730
Score = 54.7 bits (130), Expect = 2e-07
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 182 DENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCS-HSCL 239
D +EC++ G C C+N S++CEC G L D + CED++ C + G C +C
Sbjct: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1709
Query: 240 GSEKGYQCECPRGLVLSEDNHTC 262
+ Y C CP + H C
Sbjct: 1710 NTLGNYTCICPPEYMQVNGGHNC 1732
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 50/163 (30%)
Query: 149 DICDEDCHGSCSDTSECTCAPGTV-------LGPDRQTCFDENECEQNNGGCSE-ICVNL 200
D C H CS ++C PG+ D TC D +EC +N C C+N+
Sbjct: 1410 DECSNGTH-QCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNV 1468
Query: 201 KNSYRCECGVGRVLRSDGKTCEDVEGCH----------NNNGGCSHS------------- 237
+YRCEC +G SD ++C+D++ C NN G H
Sbjct: 1469 PGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGG 1528
Query: 238 ------------------CLGSEKGYQCECPRGLVLSEDNHTC 262
C+ + Y+C CP L+ C
Sbjct: 1529 NCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC 1571
Score = 50.4 bits (119), Expect = 4e-06
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 5/92 (5%)
Query: 179 TCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDV--EGCHN--NNGG 233
TC D NECE G C CVN K S+ CEC G L G+ C D+ E C+ +
Sbjct: 952 TCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDE 1011
Query: 234 CSHSCLGSEKGYQCECPRGLVLSEDNHTCQVP 265
C H G + C C G + C P
Sbjct: 1012 CIHPVPGKFRMDACCCAVGAAWGTECEECPKP 1043
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 26/120 (21%)
Query: 140 FHVYCGHFYDICDEDCHGSCSDTSEC-----TCAPGTVLGPD--------------RQTC 180
F C Y++ + +C DT+EC +C+PGT + + C
Sbjct: 1997 FKCLCNEGYELTPDG--KNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC 2054
Query: 181 FDENECEQNNGGCS-EICVNLKNSYRCECGVGRVLRSDGKTCEDVEG--CHNN--NGGCS 235
D NEC+++ C C N ++C C G VL +G+ C D C N NG CS
Sbjct: 2055 IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCS 2114
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/149 (26%), Positives = 57/149 (38%), Gaps = 42/149 (28%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDEN--EC-----EQNNGGCS---EICVNLKN 202
+G C +T EC C P L P C D C + +G S EI V +
Sbjct: 1544 NGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSR 1603
Query: 203 SYRCECGVGRVLRSDGKTC---------------------------EDVEGCHNNNGGCS 235
S C C +G+ + +TC ED++ C G C
Sbjct: 1604 SSCC-CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQ 1662
Query: 236 H-SCLGSEKGYQCECPRGLVLSEDNHTCQ 263
+C+ + +QCECP+G LSED C+
Sbjct: 1663 GGNCINTFGSFQCECPQGYYLSEDTRICE 1691
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 182 DENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGC-SHSCL 239
D NEC+ G C+ C N S++C C G L + + C D++ C + C S C+
Sbjct: 1073 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1132
Query: 240 GSEKGYQCECPRG 252
+ ++CEC G
Sbjct: 1133 NTPGSFECECFEG 1145
Score = 43.5 bits (101), Expect = 5e-04
Identities = 50/202 (24%), Positives = 73/202 (36%), Gaps = 23/202 (11%)
Query: 96 GDGIVQRQACASFN---GNCCLW----NTTVEVKACPGGYYVYRLTKPSVCFHVY--CGH 146
G G+ + C S GN C N+T CPGG +R ++ C
Sbjct: 1598 GVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEG-FRPNPITIILEDIDECQE 1656
Query: 147 FYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKN 202
+C G+C +T +C C G L D + C D +EC + G C C N
Sbjct: 1657 LPGLCQG---GNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLG 1713
Query: 203 SYRCECGVGRVLRSDGKTCEDVEG--CHNNNGG--CSHSCLGSEKGYQCECPR--GLVLS 256
+Y C C + + G C D+ C+ + G C + + C C G +
Sbjct: 1714 NYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN 1773
Query: 257 EDNHTCQVPVLCKSNAIEVNIP 278
+ C P I NIP
Sbjct: 1774 KPCEPCPTPGTADFKTICGNIP 1795
Score = 37.0 bits (84), Expect = 0.046
Identities = 36/129 (27%), Positives = 45/129 (34%), Gaps = 17/129 (13%)
Query: 147 FYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNS 203
F +IC G+C++ C C G L C D +EC + +CVN
Sbjct: 1497 FQNIC---VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGR 1553
Query: 204 YRCECGVGRVLRSDGKTCED--VEGCH---NNNGGCSHSCLGSEKGY-----QCECPRGL 253
Y C C L G C D V C+ G S SC +E G C C G
Sbjct: 1554 YECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSC-NTEIGVGVSRSSCCCSLGK 1612
Query: 254 VLSEDNHTC 262
TC
Sbjct: 1613 AWGNPCETC 1621
Score = 35.4 bits (80), Expect = 0.13
Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 38/140 (27%)
Query: 133 LTKPSVC---FHVYC---------GH--FYDICDEDC-HGSCSDTSECTCAPGTVLGPDR 177
L P+VC FH YC G+ IC C G CS + CTC+ G +
Sbjct: 83 LRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQI----S 138
Query: 178 QTCFDEN--ECE---QNNGGCSEICVNLKNSYRCECGVGRVLRSDGK-TCEDVEGCHNNN 231
TC ++ +C N G C++ C+C G + G+ CE+ GC N
Sbjct: 139 STCGSKSIQQCSVRCMNGGTCAD--------DHCQCQKGYIGTYCGQPVCEN--GCQNGG 188
Query: 232 ---GGCSHSCLGSEKGYQCE 248
G +C+ G QCE
Sbjct: 189 RCIGPNRCACVYGFTGPQCE 208
>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
Length = 607
Score = 91.3 bits (225), Expect = 2e-18
Identities = 74/258 (28%), Positives = 119/258 (46%), Gaps = 18/258 (6%)
Query: 268 CKSNAIEVNIPRELV-----GGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDK 322
C S+ + V I + + G L L + +CR + V L CGT+ V +
Sbjct: 277 CSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNV-VEFSVPLNGCGTIRKVEDQS 335
Query: 323 IVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSR 382
I +N++T + S+ + I R +L I V CE T+ Y+ I S+
Sbjct: 336 ITYTNIITF----SASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI----TEDDVIQSQ 387
Query: 383 NH-GIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPT 441
N G + ++ +F+ N FE+ E+ + L +L+ + L +++C A+PT
Sbjct: 388 NALGKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTSDPNLVVFLDTCRASPT 447
Query: 442 SKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCG 501
S Y LI+ GC D++ K Y H + FQ FKF+ + V+L C+VL+C
Sbjct: 448 SDFASPT-YDLIKSGCSRDETCKVYPLFGHYGR-FQFNAFKFL-RSMSSVYLQCKVLICD 504
Query: 502 VLDERSRCAQGCHRRMRR 519
D +SRC QGC R +R
Sbjct: 505 SSDHQSRCNQGCVSRSKR 522
>gi|119220573 zymogen granule membrane glycoprotein 2 isoform 4
[Homo sapiens]
Length = 387
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/291 (26%), Positives = 122/291 (41%), Gaps = 16/291 (5%)
Query: 238 CLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLEL------FLTN 291
CL + C C + L S D H+ Q + C I+V + + L+GGL L +L +
Sbjct: 50 CLALNSTWGCFCRQDLN-SSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRD 108
Query: 292 TSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLL 351
+C + N + V I+ N + K T DFIIR + L
Sbjct: 109 PNCSSILQTEERNWV---SVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRDTILN 165
Query: 352 IPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLK 411
I C +P +S S L + +G F + +F+D + PY L
Sbjct: 166 INFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAVELS 225
Query: 412 LRDSLYFG-IEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVS--DDSVKQYTS 468
+ LY G I S ++ +C+ATPT +++KY++IR+ C + D ++ +
Sbjct: 226 VESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEEN 285
Query: 469 RDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRR 519
F V +F F G + VFLHC + +C L+E +C C R R
Sbjct: 286 GQSSESRFSVQMFMFAG-HYDLVFLHCEIHLCDSLNE--QCQPSCSRSQVR 333
>gi|119220572 zymogen granule membrane glycoprotein 2 isoform 3
[Homo sapiens]
Length = 390
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/291 (26%), Positives = 122/291 (41%), Gaps = 16/291 (5%)
Query: 238 CLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLEL------FLTN 291
CL + C C + L S D H+ Q + C I+V + + L+GGL L +L +
Sbjct: 53 CLALNSTWGCFCRQDLN-SSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRD 111
Query: 292 TSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLL 351
+C + N + V I+ N + K T DFIIR + L
Sbjct: 112 PNCSSILQTEERNWV---SVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRDTILN 168
Query: 352 IPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLK 411
I C +P +S S L + +G F + +F+D + PY L
Sbjct: 169 INFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAVELS 228
Query: 412 LRDSLYFG-IEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVS--DDSVKQYTS 468
+ LY G I S ++ +C+ATPT +++KY++IR+ C + D ++ +
Sbjct: 229 VESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEEN 288
Query: 469 RDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRR 519
F V +F F G + VFLHC + +C L+E +C C R R
Sbjct: 289 GQSSESRFSVQMFMFAG-HYDLVFLHCEIHLCDSLNE--QCQPSCSRSQVR 336
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/173 (31%), Positives = 77/173 (44%), Gaps = 17/173 (9%)
Query: 144 CGHFYDICDEDCHGSCSD---TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNL 200
C +D+C +G C + + C C G +C D NEC Q C+ IC N
Sbjct: 2406 CKVIHDVCR---NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNT 2462
Query: 201 KNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSE--- 257
+ SY+C C G +L+ DG++C+D++ C C C+ + G+ C+CP G
Sbjct: 2463 EGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSC 2522
Query: 258 -DNHTCQVPV-LCKSNAIEVNIPR----ELVGGLELFLTNTSCRGVS--NGTH 302
DN+ C + LC S I N P E G L T +SC V G H
Sbjct: 2523 IDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNH 2575
Score = 85.5 bits (210), Expect = 1e-16
Identities = 47/131 (35%), Positives = 56/131 (42%), Gaps = 8/131 (6%)
Query: 149 DICDED---CHGSCSDTSE----CTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNL 200
D C D C G +E C C PG L P+ C D NECE + C CVNL
Sbjct: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
Query: 201 KNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNH 260
Y+C C G D C D++ C NGGC C SE Y+C C G L D
Sbjct: 1175 IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQR 1234
Query: 261 TCQVPVLCKSN 271
+C C+ N
Sbjct: 1235 SCTDIDECEDN 1245
Score = 84.3 bits (207), Expect = 3e-16
Identities = 39/100 (39%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 164 ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCED 223
+C C PG PDR C D +EC NGGC C N + SY C C G L D ++C D
Sbjct: 1179 QCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTD 1238
Query: 224 VEGCHNNNGGC-SHSCLGSEKGYQCECPRGLVLSEDNHTC 262
++ C +N C C Y+C C G + SED TC
Sbjct: 1239 IDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTC 1278
Score = 80.5 bits (197), Expect = 4e-15
Identities = 41/103 (39%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 164 ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEI---CVNLKNSYRCECGVGRVLRSDGKT 220
EC C G VL DR+ C DE+ECE+ C+E C NL +Y C CG G R DG+
Sbjct: 2229 ECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG 2288
Query: 221 CEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTC 262
C D C G C + CL + Y CEC G S + C
Sbjct: 2289 CVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDEC 2331
Score = 75.5 bits (184), Expect = 1e-13
Identities = 57/192 (29%), Positives = 83/192 (43%), Gaps = 27/192 (14%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEI--CVNLKNSYRCECGV 210
H C++T+ +C+C+PG + D C D +EC CS+ C N SYRC C
Sbjct: 1336 HAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE 1393
Query: 211 GRVLRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQVPVLCK 269
G DG TC D++ C N C + CL + GY+CEC G V S D C+
Sbjct: 1394 GYT--GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE------ 1445
Query: 270 SNAIEVNIPRELVGGLELFLTNTSCRGVSN--GTHVNILFSLKTCGTVVDVVNDKIVASN 327
+ E ++P V G +C + I + L G VN+ + +
Sbjct: 1446 -DIDECSLPNICVFG--------TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1496
Query: 328 LVTGLPKQTPGS 339
++G TPGS
Sbjct: 1497 CISGNCVNTPGS 1508
Score = 73.6 bits (179), Expect = 4e-13
Identities = 47/135 (34%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
Query: 123 ACPGGYYVYRLTKPSVCFHV---YCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQT 179
AC GY+ + P F V C C+ C S + EC+C PG L PD+++
Sbjct: 1181 ACNPGYH----STPDRLFCVDIDECSIMNGGCETFCTNS-EGSYECSCQPGFALMPDQRS 1235
Query: 180 CFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGC-SHS 237
C D +ECE N C C N+ YRC C G + D KTC DV C N C S +
Sbjct: 1236 CTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT 1295
Query: 238 CLGSEKGYQCECPRG 252
C ++ + C C G
Sbjct: 1296 CENTKGSFICHCDMG 1310
Score = 73.6 bits (179), Expect = 4e-13
Identities = 42/113 (37%), Positives = 51/113 (45%), Gaps = 7/113 (6%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGR 212
+G+C + ECTC G GP TC D NEC QN C+ CVN SY C+C VG
Sbjct: 2178 NGTCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGY 2236
Query: 213 VLRSDGKTCEDVEGCHNNNGGCSH---SCLGSEKGYQCECPRGLVLSEDNHTC 262
VLR D + C+D + C C+ C Y C C G D C
Sbjct: 2237 VLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2289
Score = 72.0 bits (175), Expect = 1e-12
Identities = 40/113 (35%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVG 211
+G C +T +C C G + PD +TC D NEC C+ C NL SYRC C G
Sbjct: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPG 2003
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCS-HSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
L+++ CED++ C C+ +C +E ++C CP G LS CQ
Sbjct: 2004 YSLQNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Score = 71.2 bits (173), Expect = 2e-12
Identities = 47/165 (28%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Query: 101 QRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCS 160
++ CA G C+ N C GY LT+ C IC+ +G C
Sbjct: 495 EKNPCA---GGECINNQGSYTCQCRAGYQS-TLTRTECRDIDECLQNGRICN---NGRCI 547
Query: 161 DTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSD 217
+T C C G + D + C D +EC N + +C+N S++C C G L SD
Sbjct: 548 NTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD 607
Query: 218 GKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
G+ C+D+ C + C+ ++ Y+CEC GL + D C
Sbjct: 608 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/143 (28%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 154 DCHGSCSDTSECT---CAPGTVLGPD----------------RQTCFDENECEQNNGGCS 194
D G C D EC CA G + R C D +EC QN C+
Sbjct: 483 DLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN 542
Query: 195 E-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGL 253
C+N S+ C C G + DGK CED++ C N + C+ + ++C C G
Sbjct: 543 NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 602
Query: 254 VLSEDNHTCQVPVLCKSNAIEVN 276
L+ D C+ C++ I +N
Sbjct: 603 QLASDGRYCKDINECETPGICMN 625
Score = 68.2 bits (165), Expect = 2e-11
Identities = 38/118 (32%), Positives = 53/118 (44%), Gaps = 9/118 (7%)
Query: 149 DICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYR 205
D+C HG C +T C C G +L + C D +EC N + C N+ +
Sbjct: 2135 DVCK---HGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNPCGNGTCKNVIGGFE 2189
Query: 206 CECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
C C G TCED+ C N C+ C+ + Y+C+CP G VL ED C+
Sbjct: 2190 CTCEEG-FEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCK 2246
Score = 66.6 bits (161), Expect = 5e-11
Identities = 46/176 (26%), Positives = 73/176 (41%), Gaps = 14/176 (7%)
Query: 105 CASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSE 164
C + C N + + C G ++ +TK C G ++ E C +D
Sbjct: 1687 CMDMRRSLCYRNYYADNQTCDGEL-LFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFA 1745
Query: 165 CTCA---PGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKT 220
C PG V+ D +EC + G C +C+N+ S+RCEC VG
Sbjct: 1746 TLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLV 1805
Query: 221 CEDVEGCHNNNGGCSHS--CLGSEKGYQCECPRGLVLS-----EDNHTCQ-VPVLC 268
CED++ C N C + C+ + Y+C+C G + D + CQ +P +C
Sbjct: 1806 CEDIDEC-QNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC 1860
Score = 66.6 bits (161), Expect = 5e-11
Identities = 52/202 (25%), Positives = 75/202 (37%), Gaps = 35/202 (17%)
Query: 95 EGDGIVQRQACASFNGNC----CLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGH-FYD 149
+G+G V C + G C CL C G+ C G+ F +
Sbjct: 2285 DGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTAS--PNQDECLDNREGYCFTE 2342
Query: 150 ICDEDCHGSCSDT-----SECTCAPGTVLGPDRQTC----------------------FD 182
+ C S+ SEC C G GP + C D
Sbjct: 2343 VLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGAD 2402
Query: 183 ENECEQNNGGC-SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGS 241
+EC+ + C + CVN + SY C C G G +C D+ C+ C+ C +
Sbjct: 2403 IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNT 2462
Query: 242 EKGYQCECPRGLVLSEDNHTCQ 263
E YQC CP+G +L ED +C+
Sbjct: 2463 EGSYQCSCPKGYILQEDGRSCK 2484
Score = 66.2 bits (160), Expect = 7e-11
Identities = 47/169 (27%), Positives = 70/169 (41%), Gaps = 37/169 (21%)
Query: 136 PSVCFHVYC----GHFYDICD---------------EDC------HGSCSDTS---ECTC 167
P++C H C G FY +C +C +G+C +T C C
Sbjct: 1857 PNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRC 1916
Query: 168 APGTVLGPDRQTCFDENECEQNNGGCSEI--CVNLKNSYRCECGVGRVLRSDGKTCEDVE 225
G +L + C D +EC NG C+N S++C+C G + DG+TC D+
Sbjct: 1917 NHGFILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975
Query: 226 GCHNNNGGCS-HSCLGSEKGYQCECPRGLVLS----EDNHTC-QVPVLC 268
C C+ +C + Y+C CP G L ED C + P +C
Sbjct: 1976 ECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC 2024
Score = 62.8 bits (151), Expect = 8e-10
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNN--GGCSEICVNLKNSYRCECGVGRVLRSDGKTCE 222
C+C G + C DENEC + GG S C N SY+C C G C+
Sbjct: 2590 CSCPQGYLQHYQWNQCVDENECLSAHICGGAS--CHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
Query: 223 DVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
D+ C + CS+ C +E GY C CP G
Sbjct: 2648 DINECGSAQAPCSYGCSNTEGGYLCGCPPG 2677
Score = 62.4 bits (150), Expect = 1e-09
Identities = 55/198 (27%), Positives = 72/198 (36%), Gaps = 27/198 (13%)
Query: 79 HCGTHAPVWLNGSHPLEGDGIVQRQACA---SFNGNCCLWN-------TTVEVKACPGGY 128
HCG PV +G L G V CA F G C + T + + C G
Sbjct: 144 HCGQ--PVCESGC--LNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQL 199
Query: 129 YVYRLTKPSVCFHV--YCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENEC 186
TK C V GH ++C H C G + C D +EC
Sbjct: 200 SGIVCTKTLCCATVGRAWGHPCEMCPAQPH---------PCRRGFIPNIRTGACQDVDEC 250
Query: 187 EQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGC-SHSCLGSEKG 244
+ G C C+N S+ C+C G L + CED++ C G C C +
Sbjct: 251 QAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSS 310
Query: 245 YQCECPRGLVLSEDNHTC 262
Y C+CP G S D C
Sbjct: 311 YFCKCPPGFYTSPDGTRC 328
Score = 62.4 bits (150), Expect = 1e-09
Identities = 61/227 (26%), Positives = 81/227 (35%), Gaps = 36/227 (15%)
Query: 63 TGMAGDAMPTFCIPENHCGTHAPVWLN-------GSHPL----------EGDGIVQRQAC 105
TG D T C+ N C AP N GS+ +G C
Sbjct: 2431 TGYTPDITGTSCVDLNECN-QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC 2489
Query: 106 ASFNGNC---CLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDT 162
A+ NC C+ CP G+ + S + C ++C G C +T
Sbjct: 2490 ATKQHNCQFLCVNTIGGFTCKCPPGFTQHHT---SCIDNNECTSDINLCGSK--GICQNT 2544
Query: 163 S---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGK 219
C C G L +C D +ECE N+ C C N+ YRC C G +
Sbjct: 2545 PGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGGYRCSCPQGYLQHYQWN 2603
Query: 220 TCEDVEGC---HNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
C D C H G H+ LGS Y+C CP G + + CQ
Sbjct: 2604 QCVDENECLSAHICGGASCHNTLGS---YKCMCPAGFQYEQFSGGCQ 2647
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/260 (24%), Positives = 102/260 (39%), Gaps = 25/260 (9%)
Query: 73 FCIPENHCGTHAPVWLNGSHPLEGDGIVQRQA----CASFNGNCCLWNTTVEVKACPGGY 128
+C N C T + +NG + DG + + +G C+ T C GGY
Sbjct: 610 YCKDINECETPG-ICMNG-RCVNTDGSYRCECFPGLAVGLDGRVCV--DTHMRSTCYGGY 665
Query: 129 YVYRLTKP-------SVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCF 181
+ KP S C + + + C S + C+ G +
Sbjct: 666 KRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGM---TSAGS 722
Query: 182 DENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH-SCL 239
D NEC + C IC NL+ +Y+C C G + S GK C D+ C N+ C + C
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCR 782
Query: 240 GSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSN 299
+ + C CP+G + D TC+ C+S+ + + G F+ S +
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGS---FICECSSESTLD 839
Query: 300 GTHVNILFSLK-TC-GTVVD 317
T + ++K TC TV+D
Sbjct: 840 PTKTICIETIKGTCWQTVID 859
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/187 (26%), Positives = 72/187 (38%), Gaps = 26/187 (13%)
Query: 105 CASFNGNCCLWNTTVEVK---ACPGGYYVYRLTKPSVCFHV-YCGHFYDICDEDCHGSCS 160
C+ NG C + T E +C G+ + + C + C +ICD G C+
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFAL--MPDQRSCTDIDECEDNPNICDG---GQCT 1255
Query: 161 DTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGC-SEICVNLKNSYRCECGVGRVLRS 216
+ C C G + D +TC D NEC+ N C S C N K S+ C C +G +
Sbjct: 1256 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKK 1315
Query: 217 DGKTCEDVEGCH--NNNGGCSHSCLGSEKGYQCECPRGLV-----------LSEDNHTCQ 263
C D+ C +N G C + ++C C G + S H C
Sbjct: 1316 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1375
Query: 264 VPVLCKS 270
CK+
Sbjct: 1376 QHADCKN 1382
Score = 61.6 bits (148), Expect = 2e-09
Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 7/121 (5%)
Query: 149 DICDEDCH----GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLK 201
D C E+ + G C + C C G V D + C D +EC N C NL
Sbjct: 1406 DECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLP 1465
Query: 202 NSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHT 261
+RCEC +G L G C DV C + S +C+ + Y C+CP L+
Sbjct: 1466 GLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVG 1525
Query: 262 C 262
C
Sbjct: 1526 C 1526
Score = 59.3 bits (142), Expect = 9e-09
Identities = 48/167 (28%), Positives = 67/167 (40%), Gaps = 25/167 (14%)
Query: 112 CCLWNTTVEVKACPGG--YYVYRLTKPSVCFHVY--CGHFYDICDEDCHGSCSDTS---E 164
C + NT + CP G + +T F C +C HG C +T +
Sbjct: 996 CPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCT---HGKCRNTIGSFK 1052
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDG----K 219
C C G L + + C D +EC + C CVN + C+C G G K
Sbjct: 1053 CRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEG---YESGFMMMK 1109
Query: 220 TCEDVEGCHNN----NGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C D++ C + GG H+ GS Y+CECP G LS + C
Sbjct: 1110 NCMDIDECQRDPLLCRGGVCHNTEGS---YRCECPPGHQLSPNISAC 1153
Score = 58.9 bits (141), Expect = 1e-08
Identities = 38/122 (31%), Positives = 51/122 (41%), Gaps = 11/122 (9%)
Query: 157 GSCSDTSE---CTCAPGTVLGPDRQTCFDENECE--QNNGGCSEICVNLKNSYRCECGVG 211
G+C +T C C G + C D NECE +N G +C N S++C C G
Sbjct: 1294 GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPG 1353
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSH--SCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCK 269
+ DG C D++ C N CS C + Y+C C G + D TC C
Sbjct: 1354 WI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEG--YTGDGFTCTDLDECS 1409
Query: 270 SN 271
N
Sbjct: 1410 EN 1411
Score = 57.0 bits (136), Expect = 4e-08
Identities = 32/91 (35%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 164 ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCED 223
+C C PG L D + C D NECE + CVN SYRCEC G + DG+ C D
Sbjct: 595 KCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Query: 224 V---EGCHN--NNGGCSHSCLGSEKGYQCEC 249
C+ G C G+ +C C
Sbjct: 655 THMRSTCYGGYKRGQCIKPLFGAVTKSECCC 685
Score = 56.6 bits (135), Expect = 6e-08
Identities = 51/200 (25%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 99 IVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLT---KPSVCFHVYCGHFYDICD-ED 154
+ ++ C S+N WN E P L +P +Y G DI + +
Sbjct: 1714 MTKKMCCCSYNIGRA-WNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECRE 1772
Query: 155 CHGSCSD--------TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEI--CVNLKNSY 204
G C + + C C G C D +EC QN C C+N SY
Sbjct: 1773 IPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECINTAGSY 1831
Query: 205 RCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTCQ 263
RC+C G S G+ C D C CSH C+ + + C C G ++D C
Sbjct: 1832 RCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL 1890
Query: 264 VPVLCKSNAIEVNIPRELVG 283
C+ +A R +G
Sbjct: 1891 DINECERDACGNGTCRNTIG 1910
Score = 54.7 bits (130), Expect = 2e-07
Identities = 40/152 (26%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 124 CPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTC 180
CP G++ K VC + +C + C +T+ C C PG Q C
Sbjct: 1793 CPVGFFYN--DKLLVCEDIDECQNGPVCQRNAE--CINTAGSYRCDCKPGYRFTSTGQ-C 1847
Query: 181 FDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCL 239
D NEC++ CS C++ S+ C C G D C D+ C + G + +C
Sbjct: 1848 NDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACG-NGTCR 1906
Query: 240 GSEKGYQCECPRGLVLSEDNHTCQVPVLCKSN 271
+ + C C G +LS +N V N
Sbjct: 1907 NTIGSFNCRCNHGFILSHNNDCIDVDECASGN 1938
Score = 53.9 bits (128), Expect = 4e-07
Identities = 33/97 (34%), Positives = 41/97 (42%), Gaps = 17/97 (17%)
Query: 149 DICDEDCHGSCSD----------TSECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-IC 197
D C+E H C++ T C C PG PD + C DENEC+ G C C
Sbjct: 2249 DECEEGKH-DCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRC 2307
Query: 198 VNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGC 234
+N + SY CEC G + C D N G C
Sbjct: 2308 LNTRGSYTCECNDGFTASPNQDECLD-----NREGYC 2339
Score = 52.8 bits (125), Expect = 8e-07
Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 10/126 (7%)
Query: 157 GSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSE-ICVNLKNSYRCECGVGR 212
G+C +T EC C G L Q C D +EC G C C N +SY C+C G
Sbjct: 260 GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGF 319
Query: 213 VLRSDGKTCEDVEG--CHN--NNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLC 268
DG C DV C+ NG CS+ S QC C G S P +C
Sbjct: 320 YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPG--VTVAPEMC 377
Query: 269 KSNAIE 274
A E
Sbjct: 378 PIRATE 383
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/178 (23%), Positives = 63/178 (35%), Gaps = 46/178 (25%)
Query: 105 CASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSE 164
CAS NGN C + F C Y++ + +C D +E
Sbjct: 1934 CASGNGNLCRNGQCINTVGS---------------FQCQCNEGYEVAPDG--RTCVDINE 1976
Query: 165 CT-----CAPGTVLGPD--------------RQTCFDENECEQNNGGCS-EICVNLKNSY 204
C CAPGT D + C D +EC + C+ C N + S+
Sbjct: 1977 CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSF 2036
Query: 205 RCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
+C C G L S G+ C+D+ + C +G +C P+ S+ C
Sbjct: 2037 KCLCPEGFSLSSSGRRCQDLRMSY---------CYAKFEGGKCSSPKSRNHSKQECCC 2085
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/179 (24%), Positives = 64/179 (35%), Gaps = 69/179 (38%)
Query: 150 ICDEDCHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQN---NGGCSE-------- 195
+CD +G C +T CTC G + PD +TC D +ECE + NG C
Sbjct: 775 LCD---NGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICE 831
Query: 196 ------------ICVN-LKNSY-------RCECGV-GRVLRSD----------------- 217
IC+ +K + RCE + G L+S
Sbjct: 832 CSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQ 891
Query: 218 -------------GKTCEDVEGCHNNNGGCSHS-CLGSEKGYQCECPRGLVLSEDNHTC 262
G CED++ C G C + C+ + ++C+CP G+ L C
Sbjct: 892 VDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRIC 950
Score = 47.8 bits (112), Expect = 3e-05
Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 3/113 (2%)
Query: 153 EDCHGSCSDTSECTCAPGTVLGPDRQTCF--DENECEQNNGGCSE-ICVNLKNSYRCECG 209
E C + + C G P+ T D +EC++ G C C+N S++C C
Sbjct: 1575 EMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCP 1634
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
G L D + C+DV C +C + Y C CP + + C
Sbjct: 1635 TGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC 1687
Score = 42.7 bits (99), Expect = 8e-04
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 180 CFDENECEQNNGGCSE-ICVNLKNSYRCECGVGRVLRSDGKTCEDV--EGC--HNNNGGC 234
C D +ECE G C +CVN + S++C+C G L + G+ C D+ E C + C
Sbjct: 908 CEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC 967
Query: 235 SHSCLGSEKGYQCECPRG 252
+ G + C C G
Sbjct: 968 TLPIAGRHRMDACCCSVG 985
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/159 (23%), Positives = 56/159 (35%), Gaps = 43/159 (27%)
Query: 157 GSCSDTSE---CTCAPGTVLGPDRQTCFD--ENEC--------EQNNGGCS-EICVNLKN 202
G+C +T C C P L P R C D C + + CS EI V +
Sbjct: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSK 1559
Query: 203 SYRCECGVGRVLRSDGKTC---------------------------EDVEGCHNNNGGC- 234
+ C C +G+ + + C ED++ C G C
Sbjct: 1560 A-SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ 1618
Query: 235 SHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAI 273
C+ + +QC CP G L+ED C C++ I
Sbjct: 1619 GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI 1657
Score = 40.8 bits (94), Expect = 0.003
Identities = 49/199 (24%), Positives = 70/199 (35%), Gaps = 51/199 (25%)
Query: 124 CPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTS---ECTCAPGTVLGPDRQTC 180
CP GYY+ T+ VC V IC G+C +T C C P + C
Sbjct: 1633 CPTGYYLNEDTR--VCDDVNECETPGICGP---GTCYNTVGNYTCICPPDYMQVNGGNNC 1687
Query: 181 FDENE--CEQN----NGGCS-EICVNL-KNSYRCECGVGRVLRSDGKTCE---------- 222
D C +N N C E+ N+ K C +GR + C
Sbjct: 1688 MDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATL 1747
Query: 223 ------------------DVEGCHNNNGGCSHS-CLGSEKGYQCECPRG------LVLSE 257
D++ C G C + C+ ++CECP G L++ E
Sbjct: 1748 CGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCE 1807
Query: 258 DNHTCQVPVLCKSNAIEVN 276
D CQ +C+ NA +N
Sbjct: 1808 DIDECQNGPVCQRNAECIN 1826
Score = 37.4 bits (85), Expect = 0.035
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 6/58 (10%)
Query: 197 CVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNN--NGGCSHSCLGSEKGYQCECPRG 252
C+ S RCEC G L G+ C DV+ C N GG C+ ++ Y C+C G
Sbjct: 465 CIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGG---ECINNQGSYTCQCRAG 518
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 89.4 bits (220), Expect = 8e-18
Identities = 44/120 (36%), Positives = 54/120 (45%), Gaps = 2/120 (1%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKN-SYRCECG 209
C C C C+ G L D++TC + C N GC ICVN ++ SY CEC
Sbjct: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECY 334
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKG-YQCECPRGLVLSEDNHTCQVPVLC 268
G L D KTC + C GC H C+ G + CEC G L+ D TC V C
Sbjct: 335 EGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKC 394
Score = 87.0 bits (214), Expect = 4e-17
Identities = 42/114 (36%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLK-NSYRCECG 209
C+ C S + C C G L DR+TC +++C GC ICVN + S+ CEC
Sbjct: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECY 376
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLG-SEKGYQCECPRGLVLSEDNHTC 262
G L +D KTC + C + GC H C+ Y C+C G L+ED TC
Sbjct: 377 EGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
Score = 67.0 bits (162), Expect = 4e-11
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 186 CEQNNGGCSEICVNL-KNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKG 244
C C +C++ + + CEC G L +D KTC ++ C N GC H C+ G
Sbjct: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
Query: 245 -YQCECPRGLVLSEDNHTCQVPVLC 268
Y CEC G L+ED TC C
Sbjct: 328 SYHCECYEGYTLNEDRKTCSAQDKC 352
Score = 54.3 bits (129), Expect = 3e-07
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNL-KNSYRCECG 209
C C + + C C G L D++TC ++C + GC ICV+ SY C+C
Sbjct: 359 CQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCY 418
Query: 210 VGRVLRSDGKTCEDVE 225
G L D KTC E
Sbjct: 419 PGYTLNEDKKTCSATE 434
Score = 33.9 bits (76), Expect = 0.39
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 234 CSHSCLGSEKG-YQCECPRGLVLSEDNHTCQVPVLCKSN 271
C H C+ +G + CEC +G L+ D TC C N
Sbjct: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 86.3 bits (212), Expect = 7e-17
Identities = 87/358 (24%), Positives = 151/358 (42%), Gaps = 33/358 (9%)
Query: 211 GRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSE-KGYQCECPRGLVL----------SEDN 259
G RS G + N +G C+G++ CE G L + +
Sbjct: 1738 GEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSH 1797
Query: 260 HTCQVPVLCKSNAIEVNIPRELVGGLE-----LFLTNTSCRGVSNGTHVNILFSLK--TC 312
V CK+ +EV+I + + L + + + C G+ ++ + C
Sbjct: 1798 DIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNC 1857
Query: 313 GTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNL 372
G +V I+ N L ++ ++G+ I R + + +C + IS V
Sbjct: 1858 GNIVQSNGTHIMYKNT---LWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKP 1914
Query: 373 RNSPLEI-MSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPV-VHVSGLE 430
S + + + G F + ++K+ ++ PYR+ L RD LY G+ V + L
Sbjct: 1915 MLSVINLTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLI 1974
Query: 431 SLVESCFATPTSKIDEVLKYYLIRDGC--VSDDSVKQYTSRDHLAKHFQVPVFKFVGKDH 488
+ C+ATPT ++ L+Y++I GC + D+++ + L F V VFKF+G D+
Sbjct: 1975 LTLNKCYATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIG-DY 2033
Query: 489 KEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPI---RIDW 543
EV LHC V +C E+ C C R + + + Q ++ GPI R+DW
Sbjct: 2034 DEVHLHCAVSLCD--SEKYSCKITCPHNSR--IATDYTKEPKEQIISVGPIRRKRLDW 2087
Score = 37.0 bits (84), Expect = 0.046
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 16/91 (17%)
Query: 141 HVYCGHFYDICDED---CHGSCSDTS----ECTCAPGTVL---GPDRQTCFDENECEQNN 190
H++C +CD + C +C S + T P + GP R+ D CE +N
Sbjct: 2037 HLHCA--VSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRKRLDW--CE-DN 2091
Query: 191 GGCSEICVNLKNSYRCECGVGRVLRSDGKTC 221
GGC +IC + + C C G L+ DGK+C
Sbjct: 2092 GGCEQICTSRVDGPLCSCVTG-TLQEDGKSC 2121
Score = 32.3 bits (72), Expect = 1.1
Identities = 32/136 (23%), Positives = 50/136 (36%), Gaps = 19/136 (13%)
Query: 148 YDICDEDCHGSC------SDTSE-----CTCAPGTVLGPDRQTCFDENECEQNNGGC--- 193
Y+ C C C SD S C C G VL + ++C + C + G
Sbjct: 1378 YESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVL--NGKSCILPHSCGCYSDGKYYE 1435
Query: 194 -SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
++ N + RC C V++ D + C+ E C NG C ++ Y G
Sbjct: 1436 PKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNG--VRGCFSTKTSYCLAAGGG 1493
Query: 253 LVLSEDNHTCQVPVLC 268
+ + D + P C
Sbjct: 1494 VFRTFDGAFLRFPANC 1509
Score = 32.0 bits (71), Expect = 1.5
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 8/54 (14%)
Query: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
VG + R CED NGGC C G C C G L ED +C+
Sbjct: 2077 VGPIRRKRLDWCED-------NGGCEQICTSRVDGPLCSCVTG-TLQEDGKSCR 2122
Score = 29.3 bits (64), Expect = 9.7
Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 22/113 (19%)
Query: 142 VYCGHF--YDICDEDCHGSCSD-----------TSECTCAPGTVLGPDRQTCFDENECEQ 188
V C F Y +C C +CSD T C C G VL + C ++C
Sbjct: 595 VQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQ--CVPLHKCGC 652
Query: 189 NNGG----CSEICVNLKN-SYRCECGVGRVLRSDGKTCEDVEGCHNNNG--GC 234
+ G E N + +C C G + KTC E C +G GC
Sbjct: 653 DFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGC 705
>gi|86788132 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 84.0 bits (206), Expect = 3e-16
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 155 CHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
CH C +T C C+PG L + TC D NEC+ +N C++ C N+ S+ C+C G
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQG 282
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
L SD CED++ C ++ C + C+ + C CP+G + + TCQ
Sbjct: 283 YELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQ 333
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDV 224
C C PG ++ C D +EC C + CVN S+ C+C G L ++ TC D+
Sbjct: 199 CQCPPGYQKRGEQ--CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDI 255
Query: 225 EGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNA 272
C +N C+ C + C+C +G LS D C+ C++++
Sbjct: 256 NECDASNQ-CAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSS 302
Score = 56.6 bits (135), Expect = 6e-08
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 176 DRQTCFDENECEQNNGGC--SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGG 233
+ C D +EC C ++C+NL+ S+ C+C G R G+ C D++ C
Sbjct: 167 EHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDEC-TIPPY 223
Query: 234 CSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C C+ + + C+C G L+ +N+TC
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTC 252
Score = 30.0 bits (66), Expect = 5.7
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 5/59 (8%)
Query: 150 ICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC--SEICVNLKNSYRC 206
+C C S C C G + R TC D NECE N C E+C N +RC
Sbjct: 304 LCQYQCVNEPGKFS-CMCPQGYQVVRSR-TCQDINECETTN-ECREDEMCWNYHGGFRC 359
>gi|86788015 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 84.0 bits (206), Expect = 3e-16
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 155 CHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
CH C +T C C+PG L + TC D NEC+ +N C++ C N+ S+ C+C G
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQG 282
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
L SD CED++ C ++ C + C+ + C CP+G + + TCQ
Sbjct: 283 YELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQ 333
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDV 224
C C PG ++ C D +EC C + CVN S+ C+C G L ++ TC D+
Sbjct: 199 CQCPPGYQKRGEQ--CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDI 255
Query: 225 EGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNA 272
C +N C+ C + C+C +G LS D C+ C++++
Sbjct: 256 NECDASNQ-CAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSS 302
Score = 56.6 bits (135), Expect = 6e-08
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 176 DRQTCFDENECEQNNGGC--SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGG 233
+ C D +EC C ++C+NL+ S+ C+C G R G+ C D++ C
Sbjct: 167 EHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDEC-TIPPY 223
Query: 234 CSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C C+ + + C+C G L+ +N+TC
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTC 252
Score = 30.0 bits (66), Expect = 5.7
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 5/59 (8%)
Query: 150 ICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC--SEICVNLKNSYRC 206
+C C S C C G + R TC D NECE N C E+C N +RC
Sbjct: 304 LCQYQCVNEPGKFS-CMCPQGYQVVRSR-TCQDINECETTN-ECREDEMCWNYHGGFRC 359
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 84.0 bits (206), Expect = 3e-16
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 155 CHGSCSDTSE---CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
CH C +T C C+PG L + TC D NEC+ +N C++ C N+ S+ C+C G
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQCYNILGSFICQCNQG 282
Query: 212 RVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
L SD CED++ C ++ C + C+ + C CP+G + + TCQ
Sbjct: 283 YELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQ 333
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Query: 165 CTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDV 224
C C PG ++ C D +EC C + CVN S+ C+C G L ++ TC D+
Sbjct: 199 CQCPPGYQKRGEQ--CVDIDECTIPPY-CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDI 255
Query: 225 EGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNA 272
C +N C+ C + C+C +G LS D C+ C++++
Sbjct: 256 NECDASNQ-CAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSS 302
Score = 56.6 bits (135), Expect = 6e-08
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 176 DRQTCFDENECEQNNGGC--SEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGG 233
+ C D +EC C ++C+NL+ S+ C+C G R G+ C D++ C
Sbjct: 167 EHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDEC-TIPPY 223
Query: 234 CSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
C C+ + + C+C G L+ +N+TC
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTC 252
Score = 30.0 bits (66), Expect = 5.7
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 5/59 (8%)
Query: 150 ICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC--SEICVNLKNSYRC 206
+C C S C C G + R TC D NECE N C E+C N +RC
Sbjct: 304 LCQYQCVNEPGKFS-CMCPQGYQVVRSR-TCQDINECETTN-ECREDEMCWNYHGGFRC 359
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 84.0 bits (206), Expect = 3e-16
Identities = 42/114 (36%), Positives = 59/114 (51%), Gaps = 7/114 (6%)
Query: 155 CHGSCSDTS---ECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVG 211
C +C +T C+CA G +L D + C D NECE CS+ C N+ SY+C C G
Sbjct: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQG 970
Query: 212 RVLRSDGKTCEDVEGCHNNNG-GCSHSCLGSEKGYQCECP-RGLVLSEDNHTCQ 263
L DG TC D++ C G C+ CL YQC CP +G ++ + +C+
Sbjct: 971 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCK 1024
Score = 82.4 bits (202), Expect = 1e-15
Identities = 43/109 (39%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 155 CHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGG-CSEICVNLKNSYRCECGVGRV 213
CH + + C C G + C D NEC + G C C N SYRC C G +
Sbjct: 875 CH-NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFL 933
Query: 214 LRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTC 262
L +DGK CEDV C CS C YQC C +G L+ED HTC
Sbjct: 934 LAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTC 980
Score = 74.3 bits (181), Expect = 3e-13
Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 30/141 (21%)
Query: 153 EDCHGSCSDTSECT---------------------------CAPGTVLGPDRQTCFDENE 185
+D G+C D +ECT CA G D C D NE
Sbjct: 802 QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
Query: 186 CEQNNGGCSE--ICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGG-CSHSCLGSE 242
CE C E +C NL SYRC+C G + G+ C DV C + G C H+C +
Sbjct: 862 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTL 921
Query: 243 KGYQCECPRGLVLSEDNHTCQ 263
Y+C C G +L+ D C+
Sbjct: 922 GSYRCSCASGFLLAADGKRCE 942
Score = 63.5 bits (153), Expect = 5e-10
Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 8/111 (7%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGG-CSEICVNLKNSYRCECG 209
C ++C + + +C C G L D TC D +EC Q G C+ C+N+ SY+C C
Sbjct: 952 CSQEC-ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACP 1010
Query: 210 V-GRVLRSDGKTCEDVEGCHNNNGGCS-----HSCLGSEKGYQCECPRGLV 254
G + ++G++C+DV+ C CS H+ GS + + ECP V
Sbjct: 1011 EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1061
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 54/171 (31%)
Query: 153 EDCHGSCSDTS---ECTCAPGTVLGPDRQTCFDE-------------------------- 183
E C C +T C C PG L D +TC E
Sbjct: 614 ELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI 673
Query: 184 -------NECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH 236
N C+ +NG C ++C + S C C G + +DG +CED+ C + CS
Sbjct: 674 PLPLPQPNTCK-DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSR 732
Query: 237 S--CLGSEKGYQC----ECPRGLVLSE-----------DNHTCQVPVLCKS 270
C+ + + C C G L + HTCQ LC++
Sbjct: 733 GEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQN 783
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 18/134 (13%)
Query: 151 CDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCS--EICVNLKNSYRC-- 206
C + C + ++ C+C PG + D +C D NEC + CS E CVN S+ C
Sbjct: 689 CKQVC-STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
Query: 207 --ECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQV 264
C G L+ DG+ CEDV+ C +H+C + G+ C+ +G + C
Sbjct: 748 ALTCEPGYALK-DGE-CEDVDECAMG----THTC---QPGFLCQNTKGSFYCQARQRCMD 798
Query: 265 PVL--CKSNAIEVN 276
L + N +++N
Sbjct: 799 GFLQDPEGNCVDIN 812
Score = 38.5 bits (88), Expect = 0.016
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 182 DENECEQNNGG-CSEICVNLKNSYRCECGVGRVLRSDGKTC 221
D++EC G C +C+N SY C C G L+ DG+TC
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC 644
Score = 29.3 bits (64), Expect = 9.7
Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 8/77 (10%)
Query: 157 GSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGC----SEICVNLKNSYRCECGVGR 212
GS D E CA G D C + E + C CV+ C GV
Sbjct: 436 GSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGV-- 493
Query: 213 VLRSDGKTC--EDVEGC 227
+ +G+TC ED + C
Sbjct: 494 LGAKEGETCGAEDNDSC 510
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,754,461
Number of Sequences: 37866
Number of extensions: 1249716
Number of successful extensions: 4562
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 133
Number of HSP's that attempted gapping in prelim test: 2544
Number of HSP's gapped (non-prelim): 1154
length of query: 545
length of database: 18,247,518
effective HSP length: 107
effective length of query: 438
effective length of database: 14,195,856
effective search space: 6217784928
effective search space used: 6217784928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.