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Search of human proteins with 22748765
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748765 claudin domain containing 2 [Homo sapiens]
(167 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22748765 claudin domain containing 2 [Homo sapiens] 340 3e-94
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 55 4e-08
gi|4505907 peripheral myelin protein 22 [Homo sapiens] 49 2e-06
gi|24430165 peripheral myelin protein 22 [Homo sapiens] 49 2e-06
gi|24430163 peripheral myelin protein 22 [Homo sapiens] 49 2e-06
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 49 3e-06
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 47 8e-06
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 47 8e-06
gi|4503559 epithelial membrane protein 1 [Homo sapiens] 43 1e-04
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [... 42 3e-04
gi|10863887 claudin 1 [Homo sapiens] 41 4e-04
gi|62000698 transmembrane protein 225 [Homo sapiens] 37 0.010
gi|10938016 claudin 11 [Homo sapiens] 37 0.010
gi|88758606 prostaglandin F receptor isoform b precursor [Homo s... 35 0.039
gi|4506261 prostaglandin F receptor isoform a precursor [Homo sa... 35 0.039
gi|13899273 transmembrane protein 47 [Homo sapiens] 35 0.039
gi|5031949 natural killer cell group 7 sequence [Homo sapiens] 34 0.067
gi|157820127 claudin-like [Homo sapiens] 33 0.15
gi|4503561 epithelial membrane protein 2 [Homo sapiens] 31 0.43
gi|169171977 PREDICTED: hypothetical protein [Homo sapiens] 31 0.56
gi|169171016 PREDICTED: hypothetical protein [Homo sapiens] 31 0.56
gi|239509059 PREDICTED: hypothetical protein [Homo sapiens] 31 0.56
gi|124107616 claudin 23 [Homo sapiens] 30 0.74
gi|7656981 claudin 15 [Homo sapiens] 30 0.74
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2... 29 1.6
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2... 29 1.6
gi|169210878 PREDICTED: germ cell-specific gene 1-like protein 2... 29 1.6
gi|122937323 transmembrane protein 202 [Homo sapiens] 29 1.6
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 29 2.1
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 29 2.1
>gi|22748765 claudin domain containing 2 [Homo sapiens]
Length = 167
Score = 340 bits (873), Expect = 3e-94
Identities = 167/167 (100%), Positives = 167/167 (100%)
Query: 1 MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLA 60
MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLA
Sbjct: 1 MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLA 60
Query: 61 VTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAW 120
VTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAW
Sbjct: 61 VTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAW 120
Query: 121 KNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL 167
KNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL
Sbjct: 121 KNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL 167
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 54.7 bits (130), Expect = 4e-08
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 19/161 (11%)
Query: 6 SLQSGGILLSLVANVLMVLSTATNYWTRQQEG----HSGLWQECNHGICSSIPCQTTLAV 61
S GG+ + V +L+V++ AT++W + + H GLW+ C C QT
Sbjct: 3 SFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCY---LQTDSIA 59
Query: 62 ----TVACMVLAVGVGVVGMVMGLRIRCDE---GESLRGQTTSAFLFLGGLLLLTALIGY 114
T A M+L+ + G++MG+ + R + F L ++ AL Y
Sbjct: 60 YWNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIY 119
Query: 115 T-VKNAWKNNVF----FSWSYFSGWLALPFSILAGFCFLLA 150
T V ++ F FSWSY GW+A+ + AG ++ A
Sbjct: 120 TGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCA 160
>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 49.3 bits (116), Expect = 2e-06
Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 11/148 (7%)
Query: 12 ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECN-------HGICSSIPCQTTLAVTVA 64
I+L + VL+ +ST + W + LWQ C+ H SS P + +V A
Sbjct: 9 IVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQ-A 67
Query: 65 CMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKN-AWKNN 123
M+L++ ++ + + + R T F L GL +++A YTV++ W N
Sbjct: 68 TMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLN 127
Query: 124 VFFSW--SYFSGWLALPFSILAGFCFLL 149
+S+ +Y W+A P ++L+G +++
Sbjct: 128 SDYSYGFAYILAWVAFPLALLSGVIYVI 155
>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 49.3 bits (116), Expect = 2e-06
Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 11/148 (7%)
Query: 12 ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECN-------HGICSSIPCQTTLAVTVA 64
I+L + VL+ +ST + W + LWQ C+ H SS P + +V A
Sbjct: 9 IVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQ-A 67
Query: 65 CMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKN-AWKNN 123
M+L++ ++ + + + R T F L GL +++A YTV++ W N
Sbjct: 68 TMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLN 127
Query: 124 VFFSW--SYFSGWLALPFSILAGFCFLL 149
+S+ +Y W+A P ++L+G +++
Sbjct: 128 SDYSYGFAYILAWVAFPLALLSGVIYVI 155
>gi|24430163 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 49.3 bits (116), Expect = 2e-06
Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 11/148 (7%)
Query: 12 ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECN-------HGICSSIPCQTTLAVTVA 64
I+L + VL+ +ST + W + LWQ C+ H SS P + +V A
Sbjct: 9 IVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQ-A 67
Query: 65 CMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKN-AWKNN 123
M+L++ ++ + + + R T F L GL +++A YTV++ W N
Sbjct: 68 TMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLN 127
Query: 124 VFFSW--SYFSGWLALPFSILAGFCFLL 149
+S+ +Y W+A P ++L+G +++
Sbjct: 128 SDYSYGFAYILAWVAFPLALLSGVIYVI 155
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 48.5 bits (114), Expect = 3e-06
Identities = 53/180 (29%), Positives = 77/180 (42%), Gaps = 37/180 (20%)
Query: 4 KRSLQSGGILLSLVANVLMVLSTATNYW-------TRQQEGHSGLWQEC---------NH 47
+ ++QS G+LLSL+ +L +++T +W + GLWQ C
Sbjct: 6 RTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 48 GICSSIPCQTTLAVTVACMVLAVGVGVVG-MVMGLRIRCDE-GESLRGQTTSAFLFLGGL 105
S + L V+ M L+ G+G +G +V G + C GES R L LGG+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQR-DLKRRLLILGGI 124
Query: 106 LL----LTALIGY------TVKNAWKNNV-------FFSWSYFSGWLALPFSILAGFCFL 148
L +TAL+ TV+ W NV F + F GW A S+L G C L
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFA-GLSLLLGGCLL 183
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 47.0 bits (110), Expect = 8e-06
Identities = 52/180 (28%), Positives = 76/180 (42%), Gaps = 37/180 (20%)
Query: 4 KRSLQSGGILLSLVANVLMVLSTATNYW-------TRQQEGHSGLWQEC---------NH 47
+ ++QS G+LLS + +L +++T +W + GLWQ C
Sbjct: 6 RTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 48 GICSSIPCQTTLAVTVACMVLAVGVGVVG-MVMGLRIRCDE-GESLRGQTTSAFLFLGGL 105
S + L V+ M L+ G+G +G +V G + C GES R L LGG+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQR-DLKRRLLILGGI 124
Query: 106 LL----LTALIGY------TVKNAWKNNV-------FFSWSYFSGWLALPFSILAGFCFL 148
L +TAL+ TV+ W NV F + F GW A S+L G C L
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFA-GLSLLLGGCLL 183
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 47.0 bits (110), Expect = 8e-06
Identities = 52/180 (28%), Positives = 76/180 (42%), Gaps = 37/180 (20%)
Query: 4 KRSLQSGGILLSLVANVLMVLSTATNYW-------TRQQEGHSGLWQEC---------NH 47
+ ++QS G+LLS + +L +++T +W + GLWQ C
Sbjct: 6 RTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 48 GICSSIPCQTTLAVTVACMVLAVGVGVVG-MVMGLRIRCDE-GESLRGQTTSAFLFLGGL 105
S + L V+ M L+ G+G +G +V G + C GES R L LGG+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQR-DLKRRLLILGGI 124
Query: 106 LL----LTALIGY------TVKNAWKNNV-------FFSWSYFSGWLALPFSILAGFCFL 148
L +TAL+ TV+ W NV F + F GW A S+L G C L
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFA-GLSLLLGGCLL 183
>gi|4503559 epithelial membrane protein 1 [Homo sapiens]
Length = 157
Score = 42.7 bits (99), Expect = 1e-04
Identities = 36/147 (24%), Positives = 67/147 (45%), Gaps = 8/147 (5%)
Query: 11 GILLSLVANVLMV-LSTATNYW--TRQQEGHSGLWQECNHGICS---SIPCQTTLAVTVA 64
GI + +A V+M+ +ST N W + + GLW+ C + CS S + L A
Sbjct: 7 GIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDALKTVQA 66
Query: 65 CMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNV 124
M+L++ V+ +++ + + R + A + L +L + YT A ++
Sbjct: 67 FMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANRDGT 126
Query: 125 FF--SWSYFSGWLALPFSILAGFCFLL 149
+ +SY GW+ FS + G +L+
Sbjct: 127 QYHHGYSYILGWICFCFSFIIGVLYLV 153
>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
[Homo sapiens]
Length = 215
Score = 41.6 bits (96), Expect = 3e-04
Identities = 45/200 (22%), Positives = 73/200 (36%), Gaps = 55/200 (27%)
Query: 6 SLQSGGILLSLVANVLMVLSTATNYWTRQQEG----HSGLWQECNHGIC----SSI---- 53
S GG+ + V +L+V++ AT++W + + H GLW+ C C SI
Sbjct: 3 SFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIGEPP 62
Query: 54 -----------------------------------PCQTTLAVTVACMVLAVGVGVVGMV 78
Q T A M+L+ + G++
Sbjct: 63 GQGPGRAWGKSRADLGAQGHLYSRWRTLRLKEGKGATQAYWNATRAFMILSALCAISGII 122
Query: 79 MGLRIRCDE---GESLRGQTTSAFLFLGGLLLLTALIGYT-VKNAWKNNVF----FSWSY 130
MG+ + R + F L ++ AL YT V ++ F FSWSY
Sbjct: 123 MGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSY 182
Query: 131 FSGWLALPFSILAGFCFLLA 150
GW+A+ + AG ++ A
Sbjct: 183 ILGWVAVLMTFFAGIFYMCA 202
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 41.2 bits (95), Expect = 4e-04
Identities = 44/180 (24%), Positives = 64/180 (35%), Gaps = 48/180 (26%)
Query: 7 LQSGGILLSLVANVLMVLSTATNYW----------TRQQEGHSGLWQECNHGICSSIPCQ 56
LQ G +L+ + + ++STA W Q + GLW C I C+
Sbjct: 6 LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65
Query: 57 ---------TTLAVTVACMV-------LAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFL 100
+TL T A MV +A+ V VGM + DE + +R
Sbjct: 66 VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMR------MA 119
Query: 101 FLGGLLLLTALIGYTVKNAWKNNVF----------------FSWSYFSGWLALPFSILAG 144
+GG + L A + V AW N F + F+GW A +L G
Sbjct: 120 VIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGG 179
>gi|62000698 transmembrane protein 225 [Homo sapiens]
Length = 225
Score = 36.6 bits (83), Expect = 0.010
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 19/159 (11%)
Query: 5 RSLQSGGILLSLVANVLMVLSTATNYWT-------RQQEGHSGLWQECNHGICSSIPCQT 57
RS+Q IL S A VLMV+ + W R + HS W C C ++ +
Sbjct: 7 RSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSP-WMMC----CPALWPED 61
Query: 58 TLAVTVACMVLAVGVG-VVGMVMGLRIRCDEGESLRGQT-TSAFLFLGGLLLLTALIGYT 115
L V M ++G+ ++ +++G++ ++ Q T+ F G+ LL ALI Y
Sbjct: 62 DLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYH 121
Query: 116 VKNAWKNNVFFS-----WSYFSGWLALPFSILAGFCFLL 149
K ++ FS W ++ +L + F + G LL
Sbjct: 122 NKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLL 160
>gi|10938016 claudin 11 [Homo sapiens]
Length = 207
Score = 36.6 bits (83), Expect = 0.010
Identities = 42/176 (23%), Positives = 70/176 (39%), Gaps = 30/176 (17%)
Query: 3 VKRSLQSGGILLSLVANVLMVLSTATNYWT------------RQQEGHSGLWQEC--NHG 48
V LQ G + S V + ++++T+TN W + G GLW +C G
Sbjct: 2 VATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATG 61
Query: 49 ICSSIPCQTTLAV---TVACMVLAVGVGVVGM---------VMGLRIRCDEG--ESLRGQ 94
+ P L + AC L + V+G+ + +R+ + G + R Q
Sbjct: 62 LYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQ 121
Query: 95 TTSAFLFLGGLLLLTALIGYTV-KNAWKNNVFFSWSYFSGWLALPFSILAGFCFLL 149
L L L L A I + V + V F +S ++GW+ ++ G C +L
Sbjct: 122 LAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGG-CVIL 176
>gi|88758606 prostaglandin F receptor isoform b precursor [Homo
sapiens]
Length = 297
Score = 34.7 bits (78), Expect = 0.039
Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 49 ICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLL 108
+ S+ CQT ++V V+ + VG++ + + I + R ++ ++FL L L++
Sbjct: 16 LLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVI 75
Query: 109 TALIGYTVKNAWKNNVFFS---WSYF--SGWLALPFSI---LAGFCFLLADMIM 154
T G+ + A V+ S W F S L F I +G C LL +M
Sbjct: 76 TDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVM 129
>gi|4506261 prostaglandin F receptor isoform a precursor [Homo
sapiens]
Length = 359
Score = 34.7 bits (78), Expect = 0.039
Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 49 ICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLL 108
+ S+ CQT ++V V+ + VG++ + + I + R ++ ++FL L L++
Sbjct: 16 LLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVI 75
Query: 109 TALIGYTVKNAWKNNVFFS---WSYF--SGWLALPFSI---LAGFCFLLADMIM 154
T G+ + A V+ S W F S L F I +G C LL +M
Sbjct: 76 TDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVM 129
>gi|13899273 transmembrane protein 47 [Homo sapiens]
Length = 181
Score = 34.7 bits (78), Expect = 0.039
Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 12/148 (8%)
Query: 12 ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSI-PCQTTLA-----VTVAC 65
I L+L ++ VLS A + T + + LW+ C I C++TL+ T+A
Sbjct: 27 IFLALCLDLGAVLSPA--WVTADHQYYLSLWESCRKPASLDIWHCESTLSSDWQIATLAL 84
Query: 66 MVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVK----NAWK 121
++ + ++ ++GL C + + LF +L + +L+ Y +K + K
Sbjct: 85 LLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLK 144
Query: 122 NNVFFSWSYFSGWLALPFSILAGFCFLL 149
F+W Y W A FS + L
Sbjct: 145 IYHEFNWGYGLAWGATIFSFGGAILYCL 172
>gi|5031949 natural killer cell group 7 sequence [Homo sapiens]
Length = 165
Score = 33.9 bits (76), Expect = 0.067
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 27/159 (16%)
Query: 1 MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQ----QEGHSGLWQECNHGICSSIPCQ 56
M + RSL G L L+ +++ +T++W HSGLW + I S
Sbjct: 1 MELCRSLALLGGSLGLM---FCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISGY--- 54
Query: 57 TTLAVTVACMVLAVGVGVVGMVMGLRIRC-----DEGESLRGQTTSAFLFLGGLLLLTAL 111
+ VT ++AV +V V L + C G TT+AF + ++ A+
Sbjct: 55 --IHVTQTFSIMAVLWALVS-VSFLVLSCFPSLFPPGHGPLVSTTAAFA--AAISMVVAM 109
Query: 112 IGYTVKNAWKN------NVFFSWSYFSGWLALPFSILAG 144
YT + W FFSWS++ GW++ + G
Sbjct: 110 AVYTSER-WDQPPHPQIQTFFSWSFYLGWVSAILLLCTG 147
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 32.7 bits (73), Expect = 0.15
Identities = 38/181 (20%), Positives = 72/181 (39%), Gaps = 34/181 (18%)
Query: 4 KRSLQSGGILLSLVANVLMVLSTATNYW-------TRQQEGHSGLWQECNH-----GIC- 50
+ +Q GG+LLSL+ V ++T W + G+W+ C +C
Sbjct: 6 RAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEVATVCK 65
Query: 51 ---SSIPCQTTLAVTVACMVLAVGVGVVGMVM-GLRIRCDEGESLR----------GQTT 96
S + L V MV + G+G++G+++ C + +R G+T
Sbjct: 66 AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
Query: 97 SAFLFLGGLLLLTALIGYTVKNAWKNNV-------FFSWSYFSGWLALPFSILAGFCFLL 149
A LL ++ + T+++ W +++ F + + GW A F L G +
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
Query: 150 A 150
+
Sbjct: 186 S 186
>gi|4503561 epithelial membrane protein 2 [Homo sapiens]
Length = 167
Score = 31.2 bits (69), Expect = 0.43
Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 20/156 (12%)
Query: 12 ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHG-----ICSSIPCQTTLAVTVACM 66
I + + L+ ++T N W E + +W+ C + I S +TL A M
Sbjct: 9 IAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYSTLQAVQATM 68
Query: 67 VLAVGVGVVGMVMGLR--IRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAW---K 121
+L+ + + + + R +GE R TS + L ++ A YT + K
Sbjct: 69 ILSTILCCIAFFIFVLQLFRLKQGE--RFVLTSIIQLMSCLCVMIAASIYTDRREDIHDK 126
Query: 122 NNVFF--------SWSYFSGWLALPFSILAGFCFLL 149
N F+ +SY W+A + ++G +L+
Sbjct: 127 NAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLI 162
>gi|169171977 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 30.8 bits (68), Expect = 0.56
Identities = 28/139 (20%), Positives = 54/139 (38%), Gaps = 17/139 (12%)
Query: 31 WTRQQEGHSGLWQECNHG--ICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEG 88
W + G +GL +C+ C +T M +AV + + G ++G+ + C
Sbjct: 39 WPSEDHGSAGLQLQCSTTGTSCWGHESSDLRRMTAGFMGMAVAIILFGWIIGV-LGCCWD 97
Query: 89 ESLRGQTTSAFLFLGG----LLLLTALIGYTVK-NAWKNNVF---------FSWSYFSGW 134
L +GG + L T + G + + + ++ + WS F W
Sbjct: 98 RGLMQYVAGLLFLMGGTFCIISLCTCVAGINFELSRYPRYLYGLPDDISHGYGWSMFCAW 157
Query: 135 LALPFSILAGFCFLLADMI 153
L ++++GF LA +
Sbjct: 158 GGLGLTLISGFFCTLAPSV 176
>gi|169171016 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 30.8 bits (68), Expect = 0.56
Identities = 28/139 (20%), Positives = 54/139 (38%), Gaps = 17/139 (12%)
Query: 31 WTRQQEGHSGLWQECNHG--ICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEG 88
W + G +GL +C+ C +T M +AV + + G ++G+ + C
Sbjct: 39 WPSEDHGSAGLQLQCSTTGTSCWGHESSDLRRMTAGFMGMAVAIILFGWIIGV-LGCCWD 97
Query: 89 ESLRGQTTSAFLFLGG----LLLLTALIGYTVK-NAWKNNVF---------FSWSYFSGW 134
L +GG + L T + G + + + ++ + WS F W
Sbjct: 98 RGLMQYVAGLLFLMGGTFCIISLCTCVAGINFELSRYPRYLYGLPDDISHGYGWSMFCAW 157
Query: 135 LALPFSILAGFCFLLADMI 153
L ++++GF LA +
Sbjct: 158 GGLGLTLISGFFCTLAPSV 176
>gi|239509059 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 30.8 bits (68), Expect = 0.56
Identities = 28/139 (20%), Positives = 54/139 (38%), Gaps = 17/139 (12%)
Query: 31 WTRQQEGHSGLWQECNHG--ICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEG 88
W + G +GL +C+ C +T M +AV + + G ++G+ + C
Sbjct: 39 WPSEDHGSAGLQLQCSTTGTSCWGHESSDLRRMTAGFMGMAVAIILFGWIIGV-LGCCWD 97
Query: 89 ESLRGQTTSAFLFLGG----LLLLTALIGYTVK-NAWKNNVF---------FSWSYFSGW 134
L +GG + L T + G + + + ++ + WS F W
Sbjct: 98 RGLMQYVAGLLFLMGGTFCIISLCTCVAGINFELSRYPRYLYGLPDDISHGYGWSMFCAW 157
Query: 135 LALPFSILAGFCFLLADMI 153
L ++++GF LA +
Sbjct: 158 GGLGLTLISGFFCTLAPSV 176
>gi|124107616 claudin 23 [Homo sapiens]
Length = 292
Score = 30.4 bits (67), Expect = 0.74
Identities = 35/137 (25%), Positives = 52/137 (37%), Gaps = 22/137 (16%)
Query: 36 EGHSGLWQECNHGICSSIPCQTT----------LAVTVACMVLAVGVGVVGMVMG-LRIR 84
E + GLW C C T + V A MV ++ V+G+++ L +R
Sbjct: 44 ELYQGLWDMCREQSSRERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVR 103
Query: 85 C--DEGESLRGQTTSAFLFLGGLLLLTALIGYT---------VKNAWKNNVFFSWSYFSG 133
C DE + + LF+ GLL L + Y A V S+S G
Sbjct: 104 CWQDEPNFVLAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLG 163
Query: 134 WLALPFSILAGFCFLLA 150
+L +L GF L+
Sbjct: 164 YLGSCLLLLGGFSLALS 180
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 30.4 bits (67), Expect = 0.74
Identities = 39/180 (21%), Positives = 71/180 (39%), Gaps = 36/180 (20%)
Query: 6 SLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSG----------LWQEC---NHGI--C 50
++++ G ++ V +++ ++ +YW R H LW C + G+ C
Sbjct: 4 AVETFGFFMATVGLLMLGVTLPNSYW-RVSTVHGNVITTNTIFENLWFSCATDSLGVYNC 62
Query: 51 SSIPCQTTLAVTV----ACMVLAVGVGVVGMVMGLR-IRCDEGESLR-GQTTSAFLFLGG 104
P L+ + A M+ A+ +G +G+++G+ +RC L + G
Sbjct: 63 WEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGA 122
Query: 105 LLLLTALIGYTVKNAWKNNV---FFSWSY-----------FSGWLALPFSILAGFCFLLA 150
L +L + G + + N+ FF Y + GW A SIL G C A
Sbjct: 123 LHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCSA 182
>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 29.3 bits (64), Expect = 1.6
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 26/127 (20%)
Query: 34 QQEGHSGLWQECNHGI-CSSIPCQTTLAVTVA----CMVLAVGVGVVGMV--------MG 80
Q+ H GLWQ C + C++ +V A + L++G V+ +V +G
Sbjct: 85 QRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLG 144
Query: 81 LRIRCDEG--ESLRGQTTSA-FLFLGGLLLLTALIGYTV---------KNAWKNNVF-FS 127
R+ C LR A F+ L GLL + A + YT WK + +
Sbjct: 145 SRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQTWDYG 204
Query: 128 WSYFSGW 134
WSY W
Sbjct: 205 WSYCLAW 211
>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 29.3 bits (64), Expect = 1.6
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 26/127 (20%)
Query: 34 QQEGHSGLWQECNHGI-CSSIPCQTTLAVTVA----CMVLAVGVGVVGMV--------MG 80
Q+ H GLWQ C + C++ +V A + L++G V+ +V +G
Sbjct: 85 QRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLG 144
Query: 81 LRIRCDEG--ESLRGQTTSA-FLFLGGLLLLTALIGYTV---------KNAWKNNVF-FS 127
R+ C LR A F+ L GLL + A + YT WK + +
Sbjct: 145 SRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQTWDYG 204
Query: 128 WSYFSGW 134
WSY W
Sbjct: 205 WSYCLAW 211
>gi|169210878 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 29.3 bits (64), Expect = 1.6
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 26/127 (20%)
Query: 34 QQEGHSGLWQECNHGI-CSSIPCQTTLAVTVA----CMVLAVGVGVVGMV--------MG 80
Q+ H GLWQ C + C++ +V A + L++G V+ +V +G
Sbjct: 85 QRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLG 144
Query: 81 LRIRCDEG--ESLRGQTTSA-FLFLGGLLLLTALIGYTV---------KNAWKNNVF-FS 127
R+ C LR A F+ L GLL + A + YT WK + +
Sbjct: 145 SRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQTWDYG 204
Query: 128 WSYFSGW 134
WSY W
Sbjct: 205 WSYCLAW 211
>gi|122937323 transmembrane protein 202 [Homo sapiens]
Length = 273
Score = 29.3 bits (64), Expect = 1.6
Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 17/127 (13%)
Query: 36 EGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQT 95
E ++GLW CNH +C S + + + + V + + GL RG
Sbjct: 90 ELYAGLWTLCNHELCWSHTPKPPYYLQYSRAFFLISVFTI--LTGLGWLFSSWILNRGSM 147
Query: 96 T-------------SAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSIL 142
T SA L L L A + + ++A ++++ W+Y+ W + F +
Sbjct: 148 TTNLDLKVSMLSFISATCLLLCLNLFVAQVHWHTRDAMESDLL--WTYYLNWCSDIFYMF 205
Query: 143 AGFCFLL 149
AG LL
Sbjct: 206 AGIISLL 212
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 28.9 bits (63), Expect = 2.1
Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 25 STATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMV 67
+TA + R QEG+ G HG C + PC T + C+V
Sbjct: 1709 NTAGEHCERCQEGYYG---NAVHGSCRACPCPHTNSFATGCVV 1748
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 28.9 bits (63), Expect = 2.1
Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 25 STATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMV 67
+TA + R QEG+ G HG C + PC T + C+V
Sbjct: 100 NTAGEHCERCQEGYYG---NAVHGSCRACPCPHTNSFATGCVV 139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.138 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,602,063
Number of Sequences: 37866
Number of extensions: 203068
Number of successful extensions: 841
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 804
Number of HSP's gapped (non-prelim): 62
length of query: 167
length of database: 18,247,518
effective HSP length: 95
effective length of query: 72
effective length of database: 14,650,248
effective search space: 1054817856
effective search space used: 1054817856
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.