Guide to the Human Genome
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Search of human proteins with 22748757

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748757 truncated type I keratin KA21 [Homo sapiens]
         (295 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748757 truncated type I keratin KA21 [Homo sapiens]              579   e-165
gi|14917119 keratin 34 [Homo sapiens]                                 110   2e-24
gi|14917117 keratin 33A [Homo sapiens]                                106   3e-23
gi|24430190 keratin 15 [Homo sapiens]                                 105   4e-23
gi|10337581 type I hair keratin 3B [Homo sapiens]                     105   4e-23
gi|14917115 keratin 31 [Homo sapiens]                                 105   6e-23
gi|4504927 keratin 36 [Homo sapiens]                                  104   1e-22
gi|15431310 keratin 14 [Homo sapiens]                                 103   1e-22
gi|24430192 keratin 16 [Homo sapiens]                                 103   2e-22
gi|4557699 keratin 12 [Homo sapiens]                                  100   2e-21
gi|4557701 keratin 17 [Homo sapiens]                                  100   3e-21
gi|55770882 keratin 37 [Homo sapiens]                                  99   4e-21
gi|131412225 keratin 13 isoform a [Homo sapiens]                       99   6e-21
gi|116488398 keratin 32 [Homo sapiens]                                 98   8e-21
gi|94538345 keratin 35 [Homo sapiens]                                  98   8e-21
gi|15431318 keratin 38 [Homo sapiens]                                  97   2e-20
gi|131412228 keratin 13 isoform b [Homo sapiens]                       97   2e-20
gi|4502995 phakinin [Homo sapiens]                                     97   2e-20
gi|27894337 keratin 20 [Homo sapiens]                                  96   5e-20
gi|40354195 keratin 18 [Homo sapiens]                                  95   8e-20
gi|4557888 keratin 18 [Homo sapiens]                                   95   8e-20
gi|195972866 keratin 10 [Homo sapiens]                                 95   8e-20
gi|148277620 type I hair keratin KA35 [Homo sapiens]                   92   4e-19
gi|24234699 keratin 19 [Homo sapiens]                                  92   4e-19
gi|4504919 keratin 8 [Homo sapiens]                                    91   1e-18
gi|125490370 type I hair keratin KA36 [Homo sapiens]                   90   2e-18
gi|21264345 peripherin [Homo sapiens]                                  89   5e-18
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     88   8e-18
gi|55956899 keratin 9 [Homo sapiens]                                   87   1e-17
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    87   1e-17

>gi|22748757 truncated type I keratin KA21 [Homo sapiens]
          Length = 295

 Score =  579 bits (1492), Expect = e-165
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR
Sbjct: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
           QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ
Sbjct: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI 180
           EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI
Sbjct: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI 180

Query: 181 SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP 240
           SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP
Sbjct: 181 SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP 240

Query: 241 RLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIKPPSTAN 295
           RLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIKPPSTAN
Sbjct: 241 RLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIKPPSTAN 295


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  110 bits (274), Expect = 2e-24
 Identities = 57/151 (37%), Positives = 100/151 (66%), Gaps = 5/151 (3%)

Query: 1   MELSQLLNEIRANYEKI--LTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEA 58
           ++L+Q+LNE R+ YE +  + R ++E   +T+    E+++K++    E L++ QAE+ E 
Sbjct: 261 VDLNQVLNETRSQYEALVEINRREVEQWFATQT---EELNKQVVSSSEQLQSCQAEIIEL 317

Query: 59  RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118
           RR  + L++E+++ H +   LEN+L  SE HY  QL  ++++I  +E +L E+R  +E+Q
Sbjct: 318 RRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQ 377

Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
            QE+++LL+ + RLE EI TYR LLE E+ +
Sbjct: 378 NQEYQVLLDVRARLECEINTYRSLLESEDCK 408


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  106 bits (264), Expect = 3e-23
 Identities = 57/149 (38%), Positives = 95/149 (63%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+Q+LNE R+ YE ++  N+ E       Q EE ++K++    E L++ QAE+ E RR
Sbjct: 219 VDLNQVLNETRSQYEALVETNRREVEQWFATQTEE-LNKQVVSSSEQLQSYQAEIIELRR 277

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L++E+++ H +   LEN+L  SE  Y  QL  ++ +I  +E +L E+R  +E+Q Q
Sbjct: 278 TVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQ 337

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ + RLE EI TYR LLE E+ +
Sbjct: 338 EYQVLLDVRARLECEINTYRSLLESEDCK 366


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  105 bits (263), Expect = 4e-23
 Identities = 57/152 (37%), Positives = 100/152 (65%), Gaps = 1/152 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L E+R  YE +  +N+ + V +      E+++K++  + E ++ ++ E+ + RR
Sbjct: 269 VDLTRVLAEMREQYEAMAEKNRRD-VEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRR 327

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E++S  +++ GLENSL  +E  Y  QLQ ++ +I GLE +L E+R  +E Q Q
Sbjct: 328 TMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQ 387

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYG 152
           E++MLL+ K RLEQEIATYR LLE ++ +  G
Sbjct: 388 EYKMLLDIKTRLEQEIATYRSLLEGQDAKMAG 419



 Score = 35.0 bits (79), Expect = 0.079
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 24/194 (12%)

Query: 54  ELKEARRQWHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLETVIEGLEKELQE 110
           E+  AR      +++ E+  A+ +G+E   N L        +   DLE  IEGL +EL  
Sbjct: 180 EIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAY 239

Query: 111 VRRGIEKQLQEHEMLLNTKMRLEQEIA----TYRHLLEKEEIRYYGCIQGGKKD------ 160
           +++  E++++E    L  ++ +E + A      R L E  E +Y    +  ++D      
Sbjct: 240 LKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMRE-QYEAMAEKNRRDVEAWFF 298

Query: 161 ------KKPTTSRVGFVLPSAIINEISFTTKVPQKYENENVETVTKQAILNGSIVKESTE 214
                  K   S    +  S    EI+   +  Q+ E E    ++ +A L  S+ +  TE
Sbjct: 299 SKTEELNKEVASNTEMIQTSK--TEITDLRRTMQELEIELQSQLSMKAGLENSLAE--TE 354

Query: 215 AHGTIQTEKVDEVI 228
                Q +++  +I
Sbjct: 355 CRYATQLQQIQGLI 368


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  105 bits (263), Expect = 4e-23
 Identities = 57/149 (38%), Positives = 95/149 (63%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+Q+LNE R  YE ++  N+ E       Q EE ++K++    E L++ QAE+ E RR
Sbjct: 219 VDLNQVLNETRNQYEALVETNRREVEQWFATQTEE-LNKQVVSSSEQLQSYQAEIIELRR 277

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L++E+++ H +   LEN+L  SE  Y  QL  ++++I  +E +L E+R  +E+Q Q
Sbjct: 278 TVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQ 337

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ + RLE EI TYR LLE E+ +
Sbjct: 338 EYQVLLDVRARLECEINTYRSLLESEDCK 366



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 59/306 (19%), Positives = 119/306 (38%), Gaps = 24/306 (7%)

Query: 2   ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61
           EL  L+ E R+  ++ L     ++   T  +L++ I     K E A    Q +  +    
Sbjct: 83  ELENLIRE-RSQQQEPLLCPSYQSYFKTIEELQQKIL--CSKSENARLVVQIDNAKLAAD 139

Query: 62  WHHLQVEIE-SLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               + + E SL  +     NSL        +   DLE  +E L++EL  +++  E+++ 
Sbjct: 140 DFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVN 199

Query: 121 EHEMLLNTKMRLEQEIA---TYRHLLEKEEIRYYGCIQGGKKDKK----PTTSRVGFVLP 173
                L  ++ +E + A       +L +   +Y   ++  +++ +      T  +   + 
Sbjct: 200 TLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVV 259

Query: 174 SAIINEISFTTKVPQKYENENVETVTKQAILNGSIVKEST----EAHGTIQTEKVDEVIK 229
           S+     S+  ++ +     N   +  QA  N     E+T    EA  + Q  +V  +I 
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLIT 319

Query: 230 EWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIK 289
             E    +    L +++   +  L + A  E  + T +         L+    C +PS  
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRS--------LLESEDCKLPS-N 370

Query: 290 PPSTAN 295
           P +T N
Sbjct: 371 PCATTN 376


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  105 bits (261), Expect = 6e-23
 Identities = 56/147 (38%), Positives = 95/147 (64%), Gaps = 1/147 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++LNE R+ YE ++  N+ E       Q EE ++K++    E L++ QAE+ E RR
Sbjct: 219 VDLNRVLNETRSQYEALVETNRREVEQWFTTQTEE-LNKQVVSSSEQLQSYQAEIIELRR 277

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L++E+++ H +   LEN+L  SE  Y  QL  ++++I  +E +L E+R  +E+Q Q
Sbjct: 278 TVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQ 337

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEE 147
           E+++LL+ + RLE EI TYR LLE E+
Sbjct: 338 EYQVLLDVRARLECEINTYRSLLESED 364


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  104 bits (259), Expect = 1e-22
 Identities = 52/149 (34%), Positives = 95/149 (63%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L ++R  YE ++  N+ +       Q EE +++++    E L+  Q E+ E RR
Sbjct: 256 VDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEE-LNQQVVSSSEQLQCCQTEIIELRR 314

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L++E+++ H++   LE++L  +E  Y  QL  ++ +I  +E +L E+R  +E+Q Q
Sbjct: 315 TVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQ 374

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ K RLE EIATYRHLLE E+ +
Sbjct: 375 EYQVLLDVKARLEGEIATYRHLLEGEDCK 403


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  103 bits (258), Expect = 1e-22
 Identities = 55/149 (36%), Positives = 102/149 (68%), Gaps = 5/149 (3%)

Query: 1   MELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEA 58
           ++LS++LNE+R  YEK+  +N+   E    T+    E++++++  + E +++ ++E+ E 
Sbjct: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKT---EELNREVATNSELVQSGKSEISEL 334

Query: 59  RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118
           RR   +L++E++S  +++  LENSL  ++  Y MQL  ++ +I  +E++L ++R  +E+Q
Sbjct: 335 RRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQ 394

Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLEKEE 147
            QE+++LL+ K RLEQEIATYR LLE E+
Sbjct: 395 NQEYKILLDVKTRLEQEIATYRRLLEGED 423


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  103 bits (257), Expect = 2e-22
 Identities = 53/147 (36%), Positives = 102/147 (69%), Gaps = 1/147 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++LS++LNE+R  YE++  +N+ +   +  +   E+++K++  + E ++++++E+ E RR
Sbjct: 280 VDLSRILNEMRDQYEQMAEKNRRDAE-TWFLSKTEELNKEVASNSELVQSSRSEVTELRR 338

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E++S  +++  LENSL  ++  Y MQL  ++ +I  +E++L ++R  +E+Q Q
Sbjct: 339 VLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQ 398

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEE 147
           E+++LL+ K RLEQEIATYR LLE E+
Sbjct: 399 EYQILLDVKTRLEQEIATYRRLLEGED 425


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  100 bits (248), Expect = 2e-21
 Identities = 67/214 (31%), Positives = 122/214 (57%), Gaps = 17/214 (7%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L++LLN++RA YE I  +N+ +   +  I+   ++ K++  + E L+++++E+ + RR
Sbjct: 292 VDLTRLLNDMRAQYETIAEQNRKDAE-AWFIEKSGELRKEISTNTEQLQSSKSEVTDLRR 350

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
            + +L++E++S  A+++ LE+SL  +E  Y  QL  ++ +I  LE +L +VR   E+Q  
Sbjct: 351 AFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNV 410

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI 180
           +H+ LLN K RLE EI TYR LL+ E        QG   ++        FV  S    + 
Sbjct: 411 DHQRLLNVKARLELEIETYRRLLDGE-------AQGDGLEESL------FVTDSKSQAQS 457

Query: 181 SFTTKVPQKYENENVETVTKQAILNGSIVKESTE 214
           + ++K P K     ++TV  Q ++NG +V    +
Sbjct: 458 TDSSKDPTK--TRKIKTVV-QEMVNGEVVSSQVQ 488



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 63/283 (22%), Positives = 115/283 (40%), Gaps = 26/283 (9%)

Query: 4   SQLLNEIRANYEK--ILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61
           ++L N+IR  YE     T +  ++  S    L ED+  K+            ++  AR  
Sbjct: 151 TELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLA 210

Query: 62  WHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118
               +++ E+  A+ +G+E   N L        +   DLE  IE L +EL  +++  E +
Sbjct: 211 AEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDE 270

Query: 119 LQEHEMLLNTKMRLEQEIA---TYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSA 175
           LQ   +    ++ +E + A       LL     +Y    +  +KD     +   F+  S 
Sbjct: 271 LQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKD-----AEAWFIEKSG 325

Query: 176 -IINEISFTTKVPQKYENE---------NVE-TVTKQAILNGSIVKESTEAHG--TIQTE 222
            +  EIS  T+  Q  ++E         N+E  +  Q  +  S+     EA G    Q  
Sbjct: 326 ELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLS 385

Query: 223 KVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLET 265
           +V ++I   E    +      +++V  +  L++ A  E  +ET
Sbjct: 386 QVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIET 428


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score = 99.8 bits (247), Expect = 3e-21
 Identities = 55/167 (32%), Positives = 105/167 (62%), Gaps = 7/167 (4%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++LS++LNE+R  YEK+  +N+ +          E++++++  + E +++ ++E+ E RR
Sbjct: 247 VDLSRILNEMRDQYEKMAEKNRKDAE-DWFFSKTEELNREVATNSELVQSGKSEISELRR 305

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E++S  +++  LE +L  +E  Y +QL  ++ +I  +E++L ++R  +E+Q Q
Sbjct: 306 TMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQ 365

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSR 167
           E+++LL+ K RLEQEIATYR LLE E+          +  K+P T+R
Sbjct: 366 EYKILLDVKTRLEQEIATYRRLLEGEDAHL------TQYKKEPVTTR 406


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score = 99.0 bits (245), Expect = 4e-21
 Identities = 55/149 (36%), Positives = 94/149 (63%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L E+RA YE ++  N  +     + Q  E IS +     E L+  Q+E+ E R 
Sbjct: 267 IDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQ-SEGISLQAMSCSEELQCCQSEILELRC 325

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L+VE ++ H ++  L+NSL  +E  Y  +L  ++++I  LE++L E+R  +E+Q Q
Sbjct: 326 TVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQ 385

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ K RLE EIATYR+LLE E+ +
Sbjct: 386 EYQVLLDVKARLENEIATYRNLLESEDCK 414


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 53/152 (34%), Positives = 97/152 (63%), Gaps = 1/152 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L E+R  YE +  RN+ +       +  E ++K++  +   ++ ++ E+ E RR
Sbjct: 268 IDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAE-LNKEVSTNTAMIQTSKTEITELRR 326

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E++S  +++ GLEN++  +E  Y +QLQ ++ +I  +E +L E+R  +E Q Q
Sbjct: 327 TLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQ 386

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYG 152
           E++MLL+ K RLEQEIATYR LLE ++ +  G
Sbjct: 387 EYKMLLDIKTRLEQEIATYRSLLEGQDAKMIG 418


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score = 98.2 bits (243), Expect = 8e-21
 Identities = 50/149 (33%), Positives = 96/149 (64%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L E+R  YE ++  N+ +      +Q+EE +++++    E L+  Q+++ + RR
Sbjct: 259 VDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEE-LNQQVATSSEQLQNYQSDIIDLRR 317

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L++E+++ H++   LEN+L  SE  Y  QL  ++ +I  +E +L E+R  +E+Q Q
Sbjct: 318 TVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQ 377

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ + RLE EI TYR LLE E+ +
Sbjct: 378 EYQVLLDVRARLEGEINTYRSLLENEDCK 406


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score = 98.2 bits (243), Expect = 8e-21
 Identities = 52/149 (34%), Positives = 96/149 (64%), Gaps = 5/149 (3%)

Query: 1   MELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEA 58
           ++L+++L E+R  YE ++  N+   E  L T+    E++++++    E L++ QAE+ E 
Sbjct: 260 VDLNRVLEEMRCQYETLVENNRRDAEDWLDTQ---SEELNQQVVSSSEQLQSCQAEIIEL 316

Query: 59  RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118
           RR  + L++E+++ H++   LE++L  +E  Y  QL  ++ +I  +E +L E+R  +E+Q
Sbjct: 317 RRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQ 376

Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLEKEE 147
            QE+++LL+ + RLE EI TYR LLE E+
Sbjct: 377 NQEYQVLLDVRARLECEINTYRGLLESED 405


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 54/149 (36%), Positives = 95/149 (63%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L E+RA YE +L  N+ +     + Q E    + M   EE L+  Q+E+ E R 
Sbjct: 267 IDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEE-LQCCQSEILELRC 325

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
             + L+VE ++ H ++  L+NSL  +E  +  +L  ++++I  +E++L E+R  +E+Q Q
Sbjct: 326 TVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQ 385

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ K RLE EIATYR+LLE E+ +
Sbjct: 386 EYQVLLDVKTRLENEIATYRNLLESEDCK 414


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 52/149 (34%), Positives = 96/149 (64%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L E+R  YE +  RN+ +       +  E ++K++  +   ++ ++ E+ E RR
Sbjct: 268 IDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAE-LNKEVSTNTAMIQTSKTEITELRR 326

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E++S  +++ GLEN++  +E  Y +QLQ ++ +I  +E +L E+R  +E Q Q
Sbjct: 327 TLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQ 386

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E++MLL+ K RLEQEIATYR LLE ++ +
Sbjct: 387 EYKMLLDIKTRLEQEIATYRSLLEGQDAK 415


>gi|4502995 phakinin [Homo sapiens]
          Length = 415

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 54/146 (36%), Positives = 88/146 (60%), Gaps = 1/146 (0%)

Query: 3   LSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAA-QAELKEARRQ 61
           L  +L  IR  +E+ + +N++E     + + + +++      EE L AA + EL     Q
Sbjct: 268 LDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQ 327

Query: 62  WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121
              LQ E ESL A++RGLEN+LH ++  + M+LQ+L  V+  LE EL+E+R   E+Q QE
Sbjct: 328 VQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQE 387

Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEE 147
              LL  K +L++++A+Y  LL++EE
Sbjct: 388 RAHLLARKCQLQKDVASYHALLDREE 413


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score = 95.5 bits (236), Expect = 5e-20
 Identities = 51/152 (33%), Positives = 92/152 (60%), Gaps = 7/152 (4%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEED---ISKKMDKDEEALKAAQAELKE 57
           + L  ++NE+R  YE +  +N  E     + Q E     + +++  + E LK  + +L E
Sbjct: 233 LNLGVIMNEMRQKYEVMAQKNLQEA----KEQFERQTAVLQQQVTVNTEELKGTEVQLTE 288

Query: 58  ARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEK 117
            RR    L++E++S  +++  LE++L  ++  Y  QL +L++++  LE +L ++R  +E+
Sbjct: 289 LRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMER 348

Query: 118 QLQEHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           Q  E+ +LL+ K RLEQEIATYR LLE E+++
Sbjct: 349 QNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score = 94.7 bits (234), Expect = 8e-20
 Identities = 53/146 (36%), Positives = 88/146 (60%), Gaps = 1/146 (0%)

Query: 2   ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61
           +L++++ +IRA Y+++  +N+ E       Q+EE  +    +  E + AA+  L E RR 
Sbjct: 244 DLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAE-VGAAETTLTELRRT 302

Query: 62  WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121
              L+++++S+  ++  LENSL   E  Y +Q++ L  ++  LE EL + R   ++Q QE
Sbjct: 303 VQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQE 362

Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEE 147
           +E LLN K++LE EIATYR LLE  E
Sbjct: 363 YEALLNIKVKLEAEIATYRRLLEDGE 388


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score = 94.7 bits (234), Expect = 8e-20
 Identities = 53/146 (36%), Positives = 88/146 (60%), Gaps = 1/146 (0%)

Query: 2   ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61
           +L++++ +IRA Y+++  +N+ E       Q+EE  +    +  E + AA+  L E RR 
Sbjct: 244 DLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAE-VGAAETTLTELRRT 302

Query: 62  WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121
              L+++++S+  ++  LENSL   E  Y +Q++ L  ++  LE EL + R   ++Q QE
Sbjct: 303 VQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQE 362

Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEE 147
           +E LLN K++LE EIATYR LLE  E
Sbjct: 363 YEALLNIKVKLEAEIATYRRLLEDGE 388


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 94.7 bits (234), Expect = 8e-20
 Identities = 51/146 (34%), Positives = 93/146 (63%), Gaps = 1/146 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+QLLN +R+ YE++  +N+ +       +  ++++ ++D + E + + ++E+ E RR
Sbjct: 312 VDLTQLLNNMRSQYEQLAEQNRKDAEAWFN-EKSKELTTEIDNNIEQISSYKSEITELRR 370

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E++S  A+++ LE SL  +E  Y +QL  ++  I  LE++LQ++R   E Q  
Sbjct: 371 NVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNT 430

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKE 146
           E++ LL+ K+RLE EI TYR LLE E
Sbjct: 431 EYQQLLDIKIRLENEIQTYRSLLEGE 456



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 47/234 (20%), Positives = 95/234 (40%), Gaps = 24/234 (10%)

Query: 54  ELKEARRQWHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLETVIEGLEKELQE 110
           ++  AR      +++ E+  A+ + +E   N L        +   DLE  IE L +EL  
Sbjct: 223 QIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAY 282

Query: 111 VRRGIEKQLQEHEMLLNTKMRLEQEIAT---YRHLLEKEEIRYYGCIQGGKKDKKPTTSR 167
           +++  E+++++   +    + +E   A       LL     +Y    +  +KD +   + 
Sbjct: 283 LKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNE 342

Query: 168 VGFVLPSAIINEI----SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEK 223
               L + I N I    S+ +++ +   N     +  Q+ L    +K+S EA        
Sbjct: 343 KSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQL---ALKQSLEAS------- 392

Query: 224 VDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRL 277
               + E EG +     +++ +  +L   L     +  C  T+   L DI++RL
Sbjct: 393 ----LAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRL 442


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score = 92.4 bits (228), Expect = 4e-19
 Identities = 56/167 (33%), Positives = 97/167 (58%), Gaps = 5/167 (2%)

Query: 2   ELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEAR 59
           +L+Q+L E+R  YE I+  N+  +E   +T+I   E++++++    +  +  Q E+ E R
Sbjct: 260 DLNQVLQEMRCQYEPIMETNRKDVEQWFNTQI---EELNQQVVTSSQQQQCCQKEIIELR 316

Query: 60  RQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQL 119
           R  + L+VE+++ H +    E  L  +E  Y   L  ++++I+ LE +L E+R  +E+Q 
Sbjct: 317 RSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQN 376

Query: 120 QEHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTS 166
           QE+E+LL+ K RLE EI TYR LLE  + +     +  K +  P TS
Sbjct: 377 QEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTS 423


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score = 92.4 bits (228), Expect = 4e-19
 Identities = 50/151 (33%), Positives = 98/151 (64%), Gaps = 5/151 (3%)

Query: 2   ELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEAR 59
           +L+++L+++R+ YE +  +N+   E   ++R    E++++++    E L+ +++E+ + R
Sbjct: 244 DLAKILSDMRSQYEVMAEQNRKDAEAWFTSRT---EELNREVAGHTEQLQMSRSEVTDLR 300

Query: 60  RQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQL 119
           R    L++E++S  +++  LE++L  +E  +  QL  ++ +I G+E +L +VR   E+Q 
Sbjct: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360

Query: 120 QEHEMLLNTKMRLEQEIATYRHLLEKEEIRY 150
           QE++ L++ K RLEQEIATYR LLE +E  Y
Sbjct: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQEDHY 391


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 53/169 (31%), Positives = 89/169 (52%), Gaps = 1/169 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           +++  ++ E++A YE I  R++ E     +I+ EE +     K  + L+  + E+ E  R
Sbjct: 254 LDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEE-LQSLAGKHGDDLRRTKTEISEMNR 312

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               LQ EIE L      LE ++  +EQ  ++ ++D    +  LE  LQ  ++ + +QL+
Sbjct: 313 NISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLR 372

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVG 169
           E++ L+N K+ L+ EIATYR LLE EE R    +Q      K T+   G
Sbjct: 373 EYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAG 421


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 49/149 (32%), Positives = 90/149 (60%), Gaps = 1/149 (0%)

Query: 1   MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60
           ++L+++L+E+R   E +L  N+ E      +Q EE ++++     E L+  Q E+ E +R
Sbjct: 252 LDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEE-LNQQQLSSAEQLQGCQMEILELKR 310

Query: 61  QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120
               L++E+++  ++   LE ++  +E  Y  QL  ++ +I+ LE +L E+R  +E+Q Q
Sbjct: 311 TASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQ 370

Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           E+++LL+ K RLE EI TY  LL+ E+ R
Sbjct: 371 EYQVLLDVKARLEGEINTYWGLLDSEDSR 399



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 23/159 (14%)

Query: 2   ELSQLLNEIRANY-EKILTRNQIETVLSTRIQLE-------------------EDISKKM 41
           E  Q LN+  A+Y EK+ +  +    L +RIQ +                   ED+ +K+
Sbjct: 91  ETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKI 150

Query: 42  DKDEEALKAAQAELKEARRQWHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLE 98
              +        +L   +      + + ES  ++ + LE   +SLH   +   +   DLE
Sbjct: 151 LCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLE 210

Query: 99  TVIEGLEKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIA 137
             +E L+++L  +++  E+++      L  ++ +E + A
Sbjct: 211 AHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTA 249


>gi|21264345 peripherin [Homo sapiens]
          Length = 470

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 1/148 (0%)

Query: 2   ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61
           EL+  L +IRA YE I  +N  E     + +   D+S   +++ EAL+ A+ E+ E+RRQ
Sbjct: 260 ELTAALRDIRAQYESIAAKNLQEAEEWYKSKYA-DLSDAANRNHEALRQAKQEMNESRRQ 318

Query: 62  WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121
              L  E++ L      L   L   E+ + ++    +     LE+EL++++  + + L+E
Sbjct: 319 IQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLRE 378

Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEEIR 149
           ++ LLN KM L+ EIATYR LLE EE R
Sbjct: 379 YQELLNVKMALDIEIATYRKLLEGEESR 406


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 88.2 bits (217), Expect = 8e-18
 Identities = 67/240 (27%), Positives = 108/240 (45%), Gaps = 12/240 (5%)

Query: 2   ELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEAR 59
           +LS  L +IRA YEK+  +N    E    +R  +   +++   K+ +A++AA+ E+ E+R
Sbjct: 253 DLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTV---LTESAAKNTDAVRAAKDEVSESR 309

Query: 60  RQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQL 119
           R      +EIE+   +   LE  L   E      +  ++  I  LE EL+  +  + + L
Sbjct: 310 RLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYL 369

Query: 120 QEHEMLLNTKMRLEQEIATYRHLLEKEEIRY----YGCIQGGKKDKKPTTSRV---GFVL 172
           +E++ LLN KM L+ EIA YR LLE EE R      G I  G         R    G   
Sbjct: 370 KEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQT 429

Query: 173 PSAIINEISFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWE 232
            S +++  SF +      + E +E             K+   + G  + E+ D+   E E
Sbjct: 430 SSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEE 489


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 52/146 (35%), Positives = 90/146 (61%), Gaps = 7/146 (4%)

Query: 2   ELSQLLNEIRANYEKILTRNQ--IETVLSTRI-QLEEDISKKMDKDEEALKAAQAELKEA 58
           +L++ LN++R  YE+++ +N+  IE    T+I Q+E ++S    + + + K    E+ + 
Sbjct: 318 DLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAK----EVTQL 373

Query: 59  RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118
           R     L++E++S  + +  LE SL  ++  Y  QLQ ++  I  LE ++ +VR+ IE Q
Sbjct: 374 RHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQ 433

Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLE 144
            QE+ +LL+ KMRLE+EI TY +LLE
Sbjct: 434 NQEYSLLLSIKMRLEKEIETYHNLLE 459


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 80/277 (28%), Positives = 128/277 (46%), Gaps = 43/277 (15%)

Query: 2   ELSQLLNEIRANYEKILTRNQIETVLST-----RIQLEEDISKKM--------------- 41
           E++ LL +I+A++  +  ++ ++T +ST     R QLE    + M               
Sbjct: 241 EVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLT 300

Query: 42  ---DKDEEALKAAQAELKEARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLE 98
              ++++EA+++A+ E+ E RRQ     +E+ES+   +  LE  L   E+ +   L   +
Sbjct: 301 EAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQ 360

Query: 99  TVIEGLEKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIATYRHLLEKEEIR---YYGCIQ 155
             I+ LE EL+  +  + + L+E++ LLN KM L+ EIA YR LLE EE R   + G I 
Sbjct: 361 DTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSIT 420

Query: 156 G-----------GKKDKKPTTSRVGFVLPSAIINEISFTTKV-PQKYENENVETVTKQAI 203
           G             K +KP        +    + EI   TKV  +K E E   T   +  
Sbjct: 421 GPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEE- 479

Query: 204 LNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP 240
           L  S+ +E  EA      EK +E   E E    K +P
Sbjct: 480 LAVSMKEEKKEA----AEEKEEEPEAEEEEVAAKKSP 512


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,251,427
Number of Sequences: 37866
Number of extensions: 439385
Number of successful extensions: 4376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 524
Number of HSP's that attempted gapping in prelim test: 2361
Number of HSP's gapped (non-prelim): 2093
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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