BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|22748757 truncated type I keratin KA21 [Homo sapiens] (295 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22748757 truncated type I keratin KA21 [Homo sapiens] 579 e-165 gi|14917119 keratin 34 [Homo sapiens] 110 2e-24 gi|14917117 keratin 33A [Homo sapiens] 106 3e-23 gi|24430190 keratin 15 [Homo sapiens] 105 4e-23 gi|10337581 type I hair keratin 3B [Homo sapiens] 105 4e-23 gi|14917115 keratin 31 [Homo sapiens] 105 6e-23 gi|4504927 keratin 36 [Homo sapiens] 104 1e-22 gi|15431310 keratin 14 [Homo sapiens] 103 1e-22 gi|24430192 keratin 16 [Homo sapiens] 103 2e-22 gi|4557699 keratin 12 [Homo sapiens] 100 2e-21 gi|4557701 keratin 17 [Homo sapiens] 100 3e-21 gi|55770882 keratin 37 [Homo sapiens] 99 4e-21 gi|131412225 keratin 13 isoform a [Homo sapiens] 99 6e-21 gi|116488398 keratin 32 [Homo sapiens] 98 8e-21 gi|94538345 keratin 35 [Homo sapiens] 98 8e-21 gi|15431318 keratin 38 [Homo sapiens] 97 2e-20 gi|131412228 keratin 13 isoform b [Homo sapiens] 97 2e-20 gi|4502995 phakinin [Homo sapiens] 97 2e-20 gi|27894337 keratin 20 [Homo sapiens] 96 5e-20 gi|40354195 keratin 18 [Homo sapiens] 95 8e-20 gi|4557888 keratin 18 [Homo sapiens] 95 8e-20 gi|195972866 keratin 10 [Homo sapiens] 95 8e-20 gi|148277620 type I hair keratin KA35 [Homo sapiens] 92 4e-19 gi|24234699 keratin 19 [Homo sapiens] 92 4e-19 gi|4504919 keratin 8 [Homo sapiens] 91 1e-18 gi|125490370 type I hair keratin KA36 [Homo sapiens] 90 2e-18 gi|21264345 peripherin [Homo sapiens] 89 5e-18 gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 88 8e-18 gi|55956899 keratin 9 [Homo sapiens] 87 1e-17 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 87 1e-17 >gi|22748757 truncated type I keratin KA21 [Homo sapiens] Length = 295 Score = 579 bits (1492), Expect = e-165 Identities = 295/295 (100%), Positives = 295/295 (100%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR Sbjct: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ Sbjct: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI 180 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI Sbjct: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI 180 Query: 181 SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP 240 SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP Sbjct: 181 SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP 240 Query: 241 RLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIKPPSTAN 295 RLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIKPPSTAN Sbjct: 241 RLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIKPPSTAN 295 >gi|14917119 keratin 34 [Homo sapiens] Length = 436 Score = 110 bits (274), Expect = 2e-24 Identities = 57/151 (37%), Positives = 100/151 (66%), Gaps = 5/151 (3%) Query: 1 MELSQLLNEIRANYEKI--LTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEA 58 ++L+Q+LNE R+ YE + + R ++E +T+ E+++K++ E L++ QAE+ E Sbjct: 261 VDLNQVLNETRSQYEALVEINRREVEQWFATQT---EELNKQVVSSSEQLQSCQAEIIEL 317 Query: 59 RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118 RR + L++E+++ H + LEN+L SE HY QL ++++I +E +L E+R +E+Q Sbjct: 318 RRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQ 377 Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 QE+++LL+ + RLE EI TYR LLE E+ + Sbjct: 378 NQEYQVLLDVRARLECEINTYRSLLESEDCK 408 >gi|14917117 keratin 33A [Homo sapiens] Length = 404 Score = 106 bits (264), Expect = 3e-23 Identities = 57/149 (38%), Positives = 95/149 (63%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+Q+LNE R+ YE ++ N+ E Q EE ++K++ E L++ QAE+ E RR Sbjct: 219 VDLNQVLNETRSQYEALVETNRREVEQWFATQTEE-LNKQVVSSSEQLQSYQAEIIELRR 277 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L++E+++ H + LEN+L SE Y QL ++ +I +E +L E+R +E+Q Q Sbjct: 278 TVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQ 337 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ + RLE EI TYR LLE E+ + Sbjct: 338 EYQVLLDVRARLECEINTYRSLLESEDCK 366 >gi|24430190 keratin 15 [Homo sapiens] Length = 456 Score = 105 bits (263), Expect = 4e-23 Identities = 57/152 (37%), Positives = 100/152 (65%), Gaps = 1/152 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L E+R YE + +N+ + V + E+++K++ + E ++ ++ E+ + RR Sbjct: 269 VDLTRVLAEMREQYEAMAEKNRRD-VEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRR 327 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E++S +++ GLENSL +E Y QLQ ++ +I GLE +L E+R +E Q Q Sbjct: 328 TMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQ 387 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYG 152 E++MLL+ K RLEQEIATYR LLE ++ + G Sbjct: 388 EYKMLLDIKTRLEQEIATYRSLLEGQDAKMAG 419 Score = 35.0 bits (79), Expect = 0.079 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 24/194 (12%) Query: 54 ELKEARRQWHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLETVIEGLEKELQE 110 E+ AR +++ E+ A+ +G+E N L + DLE IEGL +EL Sbjct: 180 EIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAY 239 Query: 111 VRRGIEKQLQEHEMLLNTKMRLEQEIA----TYRHLLEKEEIRYYGCIQGGKKD------ 160 +++ E++++E L ++ +E + A R L E E +Y + ++D Sbjct: 240 LKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMRE-QYEAMAEKNRRDVEAWFF 298 Query: 161 ------KKPTTSRVGFVLPSAIINEISFTTKVPQKYENENVETVTKQAILNGSIVKESTE 214 K S + S EI+ + Q+ E E ++ +A L S+ + TE Sbjct: 299 SKTEELNKEVASNTEMIQTSK--TEITDLRRTMQELEIELQSQLSMKAGLENSLAE--TE 354 Query: 215 AHGTIQTEKVDEVI 228 Q +++ +I Sbjct: 355 CRYATQLQQIQGLI 368 >gi|10337581 type I hair keratin 3B [Homo sapiens] Length = 404 Score = 105 bits (263), Expect = 4e-23 Identities = 57/149 (38%), Positives = 95/149 (63%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+Q+LNE R YE ++ N+ E Q EE ++K++ E L++ QAE+ E RR Sbjct: 219 VDLNQVLNETRNQYEALVETNRREVEQWFATQTEE-LNKQVVSSSEQLQSYQAEIIELRR 277 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L++E+++ H + LEN+L SE Y QL ++++I +E +L E+R +E+Q Q Sbjct: 278 TVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQ 337 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ + RLE EI TYR LLE E+ + Sbjct: 338 EYQVLLDVRARLECEINTYRSLLESEDCK 366 Score = 29.6 bits (65), Expect = 3.3 Identities = 59/306 (19%), Positives = 119/306 (38%), Gaps = 24/306 (7%) Query: 2 ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61 EL L+ E R+ ++ L ++ T +L++ I K E A Q + + Sbjct: 83 ELENLIRE-RSQQQEPLLCPSYQSYFKTIEELQQKIL--CSKSENARLVVQIDNAKLAAD 139 Query: 62 WHHLQVEIE-SLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + + E SL + NSL + DLE +E L++EL +++ E+++ Sbjct: 140 DFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVN 199 Query: 121 EHEMLLNTKMRLEQEIA---TYRHLLEKEEIRYYGCIQGGKKDKK----PTTSRVGFVLP 173 L ++ +E + A +L + +Y ++ +++ + T + + Sbjct: 200 TLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVV 259 Query: 174 SAIINEISFTTKVPQKYENENVETVTKQAILNGSIVKEST----EAHGTIQTEKVDEVIK 229 S+ S+ ++ + N + QA N E+T EA + Q +V +I Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLIT 319 Query: 230 EWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRLIMRRSCSIPSIK 289 E + L +++ + L + A E + T + L+ C +PS Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRS--------LLESEDCKLPS-N 370 Query: 290 PPSTAN 295 P +T N Sbjct: 371 PCATTN 376 >gi|14917115 keratin 31 [Homo sapiens] Length = 416 Score = 105 bits (261), Expect = 6e-23 Identities = 56/147 (38%), Positives = 95/147 (64%), Gaps = 1/147 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++LNE R+ YE ++ N+ E Q EE ++K++ E L++ QAE+ E RR Sbjct: 219 VDLNRVLNETRSQYEALVETNRREVEQWFTTQTEE-LNKQVVSSSEQLQSYQAEIIELRR 277 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L++E+++ H + LEN+L SE Y QL ++++I +E +L E+R +E+Q Q Sbjct: 278 TVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQ 337 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEE 147 E+++LL+ + RLE EI TYR LLE E+ Sbjct: 338 EYQVLLDVRARLECEINTYRSLLESED 364 >gi|4504927 keratin 36 [Homo sapiens] Length = 467 Score = 104 bits (259), Expect = 1e-22 Identities = 52/149 (34%), Positives = 95/149 (63%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L ++R YE ++ N+ + Q EE +++++ E L+ Q E+ E RR Sbjct: 256 VDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEE-LNQQVVSSSEQLQCCQTEIIELRR 314 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L++E+++ H++ LE++L +E Y QL ++ +I +E +L E+R +E+Q Q Sbjct: 315 TVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQ 374 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ K RLE EIATYRHLLE E+ + Sbjct: 375 EYQVLLDVKARLEGEIATYRHLLEGEDCK 403 >gi|15431310 keratin 14 [Homo sapiens] Length = 472 Score = 103 bits (258), Expect = 1e-22 Identities = 55/149 (36%), Positives = 102/149 (68%), Gaps = 5/149 (3%) Query: 1 MELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEA 58 ++LS++LNE+R YEK+ +N+ E T+ E++++++ + E +++ ++E+ E Sbjct: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKT---EELNREVATNSELVQSGKSEISEL 334 Query: 59 RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118 RR +L++E++S +++ LENSL ++ Y MQL ++ +I +E++L ++R +E+Q Sbjct: 335 RRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQ 394 Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLEKEE 147 QE+++LL+ K RLEQEIATYR LLE E+ Sbjct: 395 NQEYKILLDVKTRLEQEIATYRRLLEGED 423 >gi|24430192 keratin 16 [Homo sapiens] Length = 473 Score = 103 bits (257), Expect = 2e-22 Identities = 53/147 (36%), Positives = 102/147 (69%), Gaps = 1/147 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++LS++LNE+R YE++ +N+ + + + E+++K++ + E ++++++E+ E RR Sbjct: 280 VDLSRILNEMRDQYEQMAEKNRRDAE-TWFLSKTEELNKEVASNSELVQSSRSEVTELRR 338 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E++S +++ LENSL ++ Y MQL ++ +I +E++L ++R +E+Q Q Sbjct: 339 VLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQ 398 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEE 147 E+++LL+ K RLEQEIATYR LLE E+ Sbjct: 399 EYQILLDVKTRLEQEIATYRRLLEGED 425 >gi|4557699 keratin 12 [Homo sapiens] Length = 494 Score = 100 bits (248), Expect = 2e-21 Identities = 67/214 (31%), Positives = 122/214 (57%), Gaps = 17/214 (7%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L++LLN++RA YE I +N+ + + I+ ++ K++ + E L+++++E+ + RR Sbjct: 292 VDLTRLLNDMRAQYETIAEQNRKDAE-AWFIEKSGELRKEISTNTEQLQSSKSEVTDLRR 350 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + +L++E++S A+++ LE+SL +E Y QL ++ +I LE +L +VR E+Q Sbjct: 351 AFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNV 410 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSAIINEI 180 +H+ LLN K RLE EI TYR LL+ E QG ++ FV S + Sbjct: 411 DHQRLLNVKARLELEIETYRRLLDGE-------AQGDGLEESL------FVTDSKSQAQS 457 Query: 181 SFTTKVPQKYENENVETVTKQAILNGSIVKESTE 214 + ++K P K ++TV Q ++NG +V + Sbjct: 458 TDSSKDPTK--TRKIKTVV-QEMVNGEVVSSQVQ 488 Score = 35.8 bits (81), Expect = 0.046 Identities = 63/283 (22%), Positives = 115/283 (40%), Gaps = 26/283 (9%) Query: 4 SQLLNEIRANYEK--ILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61 ++L N+IR YE T + ++ S L ED+ K+ ++ AR Sbjct: 151 TELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLA 210 Query: 62 WHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118 +++ E+ A+ +G+E N L + DLE IE L +EL +++ E + Sbjct: 211 AEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDE 270 Query: 119 LQEHEMLLNTKMRLEQEIA---TYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVGFVLPSA 175 LQ + ++ +E + A LL +Y + +KD + F+ S Sbjct: 271 LQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKD-----AEAWFIEKSG 325 Query: 176 -IINEISFTTKVPQKYENE---------NVE-TVTKQAILNGSIVKESTEAHG--TIQTE 222 + EIS T+ Q ++E N+E + Q + S+ EA G Q Sbjct: 326 ELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLS 385 Query: 223 KVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLET 265 +V ++I E + +++V + L++ A E +ET Sbjct: 386 QVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIET 428 >gi|4557701 keratin 17 [Homo sapiens] Length = 432 Score = 99.8 bits (247), Expect = 3e-21 Identities = 55/167 (32%), Positives = 105/167 (62%), Gaps = 7/167 (4%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++LS++LNE+R YEK+ +N+ + E++++++ + E +++ ++E+ E RR Sbjct: 247 VDLSRILNEMRDQYEKMAEKNRKDAE-DWFFSKTEELNREVATNSELVQSGKSEISELRR 305 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E++S +++ LE +L +E Y +QL ++ +I +E++L ++R +E+Q Q Sbjct: 306 TMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQ 365 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSR 167 E+++LL+ K RLEQEIATYR LLE E+ + K+P T+R Sbjct: 366 EYKILLDVKTRLEQEIATYRRLLEGEDAHL------TQYKKEPVTTR 406 >gi|55770882 keratin 37 [Homo sapiens] Length = 449 Score = 99.0 bits (245), Expect = 4e-21 Identities = 55/149 (36%), Positives = 94/149 (63%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L E+RA YE ++ N + + Q E IS + E L+ Q+E+ E R Sbjct: 267 IDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQ-SEGISLQAMSCSEELQCCQSEILELRC 325 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L+VE ++ H ++ L+NSL +E Y +L ++++I LE++L E+R +E+Q Q Sbjct: 326 TVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQ 385 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ K RLE EIATYR+LLE E+ + Sbjct: 386 EYQVLLDVKARLENEIATYRNLLESEDCK 414 >gi|131412225 keratin 13 isoform a [Homo sapiens] Length = 458 Score = 98.6 bits (244), Expect = 6e-21 Identities = 53/152 (34%), Positives = 97/152 (63%), Gaps = 1/152 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L E+R YE + RN+ + + E ++K++ + ++ ++ E+ E RR Sbjct: 268 IDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAE-LNKEVSTNTAMIQTSKTEITELRR 326 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E++S +++ GLEN++ +E Y +QLQ ++ +I +E +L E+R +E Q Q Sbjct: 327 TLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQ 386 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYG 152 E++MLL+ K RLEQEIATYR LLE ++ + G Sbjct: 387 EYKMLLDIKTRLEQEIATYRSLLEGQDAKMIG 418 >gi|116488398 keratin 32 [Homo sapiens] Length = 448 Score = 98.2 bits (243), Expect = 8e-21 Identities = 50/149 (33%), Positives = 96/149 (64%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L E+R YE ++ N+ + +Q+EE +++++ E L+ Q+++ + RR Sbjct: 259 VDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEE-LNQQVATSSEQLQNYQSDIIDLRR 317 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L++E+++ H++ LEN+L SE Y QL ++ +I +E +L E+R +E+Q Q Sbjct: 318 TVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQ 377 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ + RLE EI TYR LLE E+ + Sbjct: 378 EYQVLLDVRARLEGEINTYRSLLENEDCK 406 >gi|94538345 keratin 35 [Homo sapiens] Length = 455 Score = 98.2 bits (243), Expect = 8e-21 Identities = 52/149 (34%), Positives = 96/149 (64%), Gaps = 5/149 (3%) Query: 1 MELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEA 58 ++L+++L E+R YE ++ N+ E L T+ E++++++ E L++ QAE+ E Sbjct: 260 VDLNRVLEEMRCQYETLVENNRRDAEDWLDTQ---SEELNQQVVSSSEQLQSCQAEIIEL 316 Query: 59 RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118 RR + L++E+++ H++ LE++L +E Y QL ++ +I +E +L E+R +E+Q Sbjct: 317 RRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQ 376 Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLEKEE 147 QE+++LL+ + RLE EI TYR LLE E+ Sbjct: 377 NQEYQVLLDVRARLECEINTYRGLLESED 405 >gi|15431318 keratin 38 [Homo sapiens] Length = 456 Score = 97.1 bits (240), Expect = 2e-20 Identities = 54/149 (36%), Positives = 95/149 (63%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L E+RA YE +L N+ + + Q E + M EE L+ Q+E+ E R Sbjct: 267 IDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEE-LQCCQSEILELRC 325 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 + L+VE ++ H ++ L+NSL +E + +L ++++I +E++L E+R +E+Q Q Sbjct: 326 TVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQ 385 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ K RLE EIATYR+LLE E+ + Sbjct: 386 EYQVLLDVKTRLENEIATYRNLLESEDCK 414 >gi|131412228 keratin 13 isoform b [Homo sapiens] Length = 420 Score = 97.1 bits (240), Expect = 2e-20 Identities = 52/149 (34%), Positives = 96/149 (64%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L E+R YE + RN+ + + E ++K++ + ++ ++ E+ E RR Sbjct: 268 IDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAE-LNKEVSTNTAMIQTSKTEITELRR 326 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E++S +++ GLEN++ +E Y +QLQ ++ +I +E +L E+R +E Q Q Sbjct: 327 TLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQ 386 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E++MLL+ K RLEQEIATYR LLE ++ + Sbjct: 387 EYKMLLDIKTRLEQEIATYRSLLEGQDAK 415 >gi|4502995 phakinin [Homo sapiens] Length = 415 Score = 96.7 bits (239), Expect = 2e-20 Identities = 54/146 (36%), Positives = 88/146 (60%), Gaps = 1/146 (0%) Query: 3 LSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAA-QAELKEARRQ 61 L +L IR +E+ + +N++E + + + +++ EE L AA + EL Q Sbjct: 268 LDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQ 327 Query: 62 WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121 LQ E ESL A++RGLEN+LH ++ + M+LQ+L V+ LE EL+E+R E+Q QE Sbjct: 328 VQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQE 387 Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEE 147 LL K +L++++A+Y LL++EE Sbjct: 388 RAHLLARKCQLQKDVASYHALLDREE 413 >gi|27894337 keratin 20 [Homo sapiens] Length = 424 Score = 95.5 bits (236), Expect = 5e-20 Identities = 51/152 (33%), Positives = 92/152 (60%), Gaps = 7/152 (4%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEED---ISKKMDKDEEALKAAQAELKE 57 + L ++NE+R YE + +N E + Q E + +++ + E LK + +L E Sbjct: 233 LNLGVIMNEMRQKYEVMAQKNLQEA----KEQFERQTAVLQQQVTVNTEELKGTEVQLTE 288 Query: 58 ARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEK 117 RR L++E++S +++ LE++L ++ Y QL +L++++ LE +L ++R +E+ Sbjct: 289 LRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMER 348 Query: 118 QLQEHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 Q E+ +LL+ K RLEQEIATYR LLE E+++ Sbjct: 349 QNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380 >gi|40354195 keratin 18 [Homo sapiens] Length = 430 Score = 94.7 bits (234), Expect = 8e-20 Identities = 53/146 (36%), Positives = 88/146 (60%), Gaps = 1/146 (0%) Query: 2 ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61 +L++++ +IRA Y+++ +N+ E Q+EE + + E + AA+ L E RR Sbjct: 244 DLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAE-VGAAETTLTELRRT 302 Query: 62 WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121 L+++++S+ ++ LENSL E Y +Q++ L ++ LE EL + R ++Q QE Sbjct: 303 VQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQE 362 Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEE 147 +E LLN K++LE EIATYR LLE E Sbjct: 363 YEALLNIKVKLEAEIATYRRLLEDGE 388 >gi|4557888 keratin 18 [Homo sapiens] Length = 430 Score = 94.7 bits (234), Expect = 8e-20 Identities = 53/146 (36%), Positives = 88/146 (60%), Gaps = 1/146 (0%) Query: 2 ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61 +L++++ +IRA Y+++ +N+ E Q+EE + + E + AA+ L E RR Sbjct: 244 DLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAE-VGAAETTLTELRRT 302 Query: 62 WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121 L+++++S+ ++ LENSL E Y +Q++ L ++ LE EL + R ++Q QE Sbjct: 303 VQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQE 362 Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEE 147 +E LLN K++LE EIATYR LLE E Sbjct: 363 YEALLNIKVKLEAEIATYRRLLEDGE 388 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 94.7 bits (234), Expect = 8e-20 Identities = 51/146 (34%), Positives = 93/146 (63%), Gaps = 1/146 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+QLLN +R+ YE++ +N+ + + ++++ ++D + E + + ++E+ E RR Sbjct: 312 VDLTQLLNNMRSQYEQLAEQNRKDAEAWFN-EKSKELTTEIDNNIEQISSYKSEITELRR 370 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E++S A+++ LE SL +E Y +QL ++ I LE++LQ++R E Q Sbjct: 371 NVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNT 430 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKE 146 E++ LL+ K+RLE EI TYR LLE E Sbjct: 431 EYQQLLDIKIRLENEIQTYRSLLEGE 456 Score = 37.0 bits (84), Expect = 0.021 Identities = 47/234 (20%), Positives = 95/234 (40%), Gaps = 24/234 (10%) Query: 54 ELKEARRQWHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLETVIEGLEKELQE 110 ++ AR +++ E+ A+ + +E N L + DLE IE L +EL Sbjct: 223 QIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAY 282 Query: 111 VRRGIEKQLQEHEMLLNTKMRLEQEIAT---YRHLLEKEEIRYYGCIQGGKKDKKPTTSR 167 +++ E+++++ + + +E A LL +Y + +KD + + Sbjct: 283 LKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNE 342 Query: 168 VGFVLPSAIINEI----SFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEK 223 L + I N I S+ +++ + N + Q+ L +K+S EA Sbjct: 343 KSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQL---ALKQSLEAS------- 392 Query: 224 VDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLETKQDNLPDIEVRL 277 + E EG + +++ + +L L + C T+ L DI++RL Sbjct: 393 ----LAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRL 442 >gi|148277620 type I hair keratin KA35 [Homo sapiens] Length = 491 Score = 92.4 bits (228), Expect = 4e-19 Identities = 56/167 (33%), Positives = 97/167 (58%), Gaps = 5/167 (2%) Query: 2 ELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEAR 59 +L+Q+L E+R YE I+ N+ +E +T+I E++++++ + + Q E+ E R Sbjct: 260 DLNQVLQEMRCQYEPIMETNRKDVEQWFNTQI---EELNQQVVTSSQQQQCCQKEIIELR 316 Query: 60 RQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQL 119 R + L+VE+++ H + E L +E Y L ++++I+ LE +L E+R +E+Q Sbjct: 317 RSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQN 376 Query: 120 QEHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTS 166 QE+E+LL+ K RLE EI TYR LLE + + + K + P TS Sbjct: 377 QEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTS 423 >gi|24234699 keratin 19 [Homo sapiens] Length = 400 Score = 92.4 bits (228), Expect = 4e-19 Identities = 50/151 (33%), Positives = 98/151 (64%), Gaps = 5/151 (3%) Query: 2 ELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEAR 59 +L+++L+++R+ YE + +N+ E ++R E++++++ E L+ +++E+ + R Sbjct: 244 DLAKILSDMRSQYEVMAEQNRKDAEAWFTSRT---EELNREVAGHTEQLQMSRSEVTDLR 300 Query: 60 RQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQL 119 R L++E++S +++ LE++L +E + QL ++ +I G+E +L +VR E+Q Sbjct: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360 Query: 120 QEHEMLLNTKMRLEQEIATYRHLLEKEEIRY 150 QE++ L++ K RLEQEIATYR LLE +E Y Sbjct: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQEDHY 391 >gi|4504919 keratin 8 [Homo sapiens] Length = 483 Score = 90.9 bits (224), Expect = 1e-18 Identities = 53/169 (31%), Positives = 89/169 (52%), Gaps = 1/169 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 +++ ++ E++A YE I R++ E +I+ EE + K + L+ + E+ E R Sbjct: 254 LDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEE-LQSLAGKHGDDLRRTKTEISEMNR 312 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 LQ EIE L LE ++ +EQ ++ ++D + LE LQ ++ + +QL+ Sbjct: 313 NISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLR 372 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIRYYGCIQGGKKDKKPTTSRVG 169 E++ L+N K+ L+ EIATYR LLE EE R +Q K T+ G Sbjct: 373 EYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAG 421 >gi|125490370 type I hair keratin KA36 [Homo sapiens] Length = 431 Score = 90.1 bits (222), Expect = 2e-18 Identities = 49/149 (32%), Positives = 90/149 (60%), Gaps = 1/149 (0%) Query: 1 MELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARR 60 ++L+++L+E+R E +L N+ E +Q EE ++++ E L+ Q E+ E +R Sbjct: 252 LDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEE-LNQQQLSSAEQLQGCQMEILELKR 310 Query: 61 QWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQ 120 L++E+++ ++ LE ++ +E Y QL ++ +I+ LE +L E+R +E+Q Q Sbjct: 311 TASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQ 370 Query: 121 EHEMLLNTKMRLEQEIATYRHLLEKEEIR 149 E+++LL+ K RLE EI TY LL+ E+ R Sbjct: 371 EYQVLLDVKARLEGEINTYWGLLDSEDSR 399 Score = 29.3 bits (64), Expect = 4.3 Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 23/159 (14%) Query: 2 ELSQLLNEIRANY-EKILTRNQIETVLSTRIQLE-------------------EDISKKM 41 E Q LN+ A+Y EK+ + + L +RIQ + ED+ +K+ Sbjct: 91 ETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKI 150 Query: 42 DKDEEALKAAQAELKEARRQWHHLQVEIESLHAVERGLE---NSLHASEQHYQMQLQDLE 98 + +L + + + ES ++ + LE +SLH + + DLE Sbjct: 151 LCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLE 210 Query: 99 TVIEGLEKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIA 137 +E L+++L +++ E+++ L ++ +E + A Sbjct: 211 AHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTA 249 >gi|21264345 peripherin [Homo sapiens] Length = 470 Score = 89.0 bits (219), Expect = 5e-18 Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 1/148 (0%) Query: 2 ELSQLLNEIRANYEKILTRNQIETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEARRQ 61 EL+ L +IRA YE I +N E + + D+S +++ EAL+ A+ E+ E+RRQ Sbjct: 260 ELTAALRDIRAQYESIAAKNLQEAEEWYKSKYA-DLSDAANRNHEALRQAKQEMNESRRQ 318 Query: 62 WHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQLQE 121 L E++ L L L E+ + ++ + LE+EL++++ + + L+E Sbjct: 319 IQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLRE 378 Query: 122 HEMLLNTKMRLEQEIATYRHLLEKEEIR 149 ++ LLN KM L+ EIATYR LLE EE R Sbjct: 379 YQELLNVKMALDIEIATYRKLLEGEESR 406 >gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] Length = 543 Score = 88.2 bits (217), Expect = 8e-18 Identities = 67/240 (27%), Positives = 108/240 (45%), Gaps = 12/240 (5%) Query: 2 ELSQLLNEIRANYEKILTRNQ--IETVLSTRIQLEEDISKKMDKDEEALKAAQAELKEAR 59 +LS L +IRA YEK+ +N E +R + +++ K+ +A++AA+ E+ E+R Sbjct: 253 DLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTV---LTESAAKNTDAVRAAKDEVSESR 309 Query: 60 RQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQL 119 R +EIE+ + LE L E + ++ I LE EL+ + + + L Sbjct: 310 RLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYL 369 Query: 120 QEHEMLLNTKMRLEQEIATYRHLLEKEEIRY----YGCIQGGKKDKKPTTSRV---GFVL 172 +E++ LLN KM L+ EIA YR LLE EE R G I G R G Sbjct: 370 KEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQT 429 Query: 173 PSAIINEISFTTKVPQKYENENVETVTKQAILNGSIVKESTEAHGTIQTEKVDEVIKEWE 232 S +++ SF + + E +E K+ + G + E+ D+ E E Sbjct: 430 SSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEE 489 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 87.4 bits (215), Expect = 1e-17 Identities = 52/146 (35%), Positives = 90/146 (61%), Gaps = 7/146 (4%) Query: 2 ELSQLLNEIRANYEKILTRNQ--IETVLSTRI-QLEEDISKKMDKDEEALKAAQAELKEA 58 +L++ LN++R YE+++ +N+ IE T+I Q+E ++S + + + K E+ + Sbjct: 318 DLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAK----EVTQL 373 Query: 59 RRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKELQEVRRGIEKQ 118 R L++E++S + + LE SL ++ Y QLQ ++ I LE ++ +VR+ IE Q Sbjct: 374 RHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQ 433 Query: 119 LQEHEMLLNTKMRLEQEIATYRHLLE 144 QE+ +LL+ KMRLE+EI TY +LLE Sbjct: 434 NQEYSLLLSIKMRLEKEIETYHNLLE 459 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 87.4 bits (215), Expect = 1e-17 Identities = 80/277 (28%), Positives = 128/277 (46%), Gaps = 43/277 (15%) Query: 2 ELSQLLNEIRANYEKILTRNQIETVLST-----RIQLEEDISKKM--------------- 41 E++ LL +I+A++ + ++ ++T +ST R QLE + M Sbjct: 241 EVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLT 300 Query: 42 ---DKDEEALKAAQAELKEARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLE 98 ++++EA+++A+ E+ E RRQ +E+ES+ + LE L E+ + L + Sbjct: 301 EAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQ 360 Query: 99 TVIEGLEKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIATYRHLLEKEEIR---YYGCIQ 155 I+ LE EL+ + + + L+E++ LLN KM L+ EIA YR LLE EE R + G I Sbjct: 361 DTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSIT 420 Query: 156 G-----------GKKDKKPTTSRVGFVLPSAIINEISFTTKV-PQKYENENVETVTKQAI 203 G K +KP + + EI TKV +K E E T + Sbjct: 421 GPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEE- 479 Query: 204 LNGSIVKESTEAHGTIQTEKVDEVIKEWEGSFFKDNP 240 L S+ +E EA EK +E E E K +P Sbjct: 480 LAVSMKEEKKEA----AEEKEEEPEAEEEEVAAKKSP 512 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,251,427 Number of Sequences: 37866 Number of extensions: 439385 Number of successful extensions: 4376 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 250 Number of HSP's successfully gapped in prelim test: 524 Number of HSP's that attempted gapping in prelim test: 2361 Number of HSP's gapped (non-prelim): 2093 length of query: 295 length of database: 18,247,518 effective HSP length: 102 effective length of query: 193 effective length of database: 14,385,186 effective search space: 2776340898 effective search space used: 2776340898 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.