Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 22748653

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748653 arrestin domain containing 1 [Homo sapiens]
         (433 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748653 arrestin domain containing 1 [Homo sapiens]               882   0.0  
gi|71040100 arrestin domain containing 2 isoform 2 [Homo sapiens]     111   1e-24
gi|18373305 arrestin domain containing 2 isoform 1 [Homo sapiens]     101   1e-21
gi|190886442 arrestin domain containing 4 [Homo sapiens]               99   1e-20
gi|32698736 arrestin domain containing 3 [Homo sapiens]                97   3e-20
gi|171184421 thioredoxin interacting protein [Homo sapiens]            82   1e-15
gi|122937478 arrestin domain containing 5 [Homo sapiens]               57   3e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   8e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   0.001
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    42   0.001
gi|146134388 YLP motif containing 1 [Homo sapiens]                     42   0.001
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  41   0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.004
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    40   0.004
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    40   0.005
gi|7657307 LIM domains containing 1 [Homo sapiens]                     39   0.007
gi|39812055 arrestin, beta 2 isoform 2 [Homo sapiens]                  39   0.009
gi|4757780 arrestin, beta 2 isoform 1 [Homo sapiens]                   39   0.009
gi|7657465 podocalyxin-like 2 [Homo sapiens]                           39   0.012
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                38   0.016
gi|116517292 cut-like 2 [Homo sapiens]                                 38   0.020
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          38   0.020
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          38   0.020
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          38   0.020
gi|117938310 sine oculis binding protein homolog [Homo sapiens]        38   0.020
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...    37   0.027
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    37   0.035
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              37   0.035
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    37   0.035
gi|163965366 nascent polypeptide-associated complex alpha subuni...    37   0.046

>gi|22748653 arrestin domain containing 1 [Homo sapiens]
          Length = 433

 Score =  882 bits (2279), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MGRVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKANDTAW 60
           MGRVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKANDTAW
Sbjct: 1   MGRVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVSNKANDTAW 60

Query: 61  VVEEGYFNSSLSLADKGSLPAGEHSFPFQFLLPATAPTSFEGPFGKIVHQVRAAIHTPRF 120
           VVEEGYFNSSLSLADKGSLPAGEHSFPFQFLLPATAPTSFEGPFGKIVHQVRAAIHTPRF
Sbjct: 61  VVEEGYFNSSLSLADKGSLPAGEHSFPFQFLLPATAPTSFEGPFGKIVHQVRAAIHTPRF 120

Query: 121 SKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVG 180
           SKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVG
Sbjct: 121 SKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVG 180

Query: 181 QALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVRTIAEVEGAGVKAWRRAQWHE 240
           QALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVRTIAEVEGAGVKAWRRAQWHE
Sbjct: 181 QALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVRTIAEVEGAGVKAWRRAQWHE 240

Query: 241 QILVPALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLP 300
           QILVPALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLP
Sbjct: 241 QILVPALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLP 300

Query: 301 PGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCP 360
           PGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCP
Sbjct: 301 PGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCP 360

Query: 361 QDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQ 420
           QDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQ
Sbjct: 361 QDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQ 420

Query: 421 SCGGVEPSLTPES 433
           SCGGVEPSLTPES
Sbjct: 421 SCGGVEPSLTPES 433


>gi|71040100 arrestin domain containing 2 isoform 2 [Homo sapiens]
          Length = 402

 Score =  111 bits (277), Expect = 1e-24
 Identities = 92/305 (30%), Positives = 147/305 (48%), Gaps = 24/305 (7%)

Query: 2   GRVQLFEISLSHGRV-VYSPGEPLAGTVRVRLGAPLPFRAIRVTCIG----------SCG 50
           G V+ F + L+ G    Y  GE L G V +   APL  RA+ V   G          S G
Sbjct: 4   GGVRSFALELARGPGGAYRGGERLCGRVLLEAAAPLRVRALEVKARGGAATHWLEGRSVG 63

Query: 51  VSNKANDTAWVVEEGYFNSSLSLADKG---SLPAGEHSFPFQFLLPATAPTSFEGPFGKI 107
           V+  ++D A   E       L L D G   +LP G H F F F LP T  TSFEG  G +
Sbjct: 64  VNAVSSDYA-AAETYLRRRQLLLRDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKHGSV 122

Query: 108 VHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVV 167
            + ++A +H P +    +   VF ++ P+++N+ P +  P   +  K         G V 
Sbjct: 123 RYCIKATLHRP-WVPARRARKVFTVIEPVDINT-PALLAPQAGAREKVARSWYCNRGLVS 180

Query: 168 LTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVR-TIAEVE 226
           L+A  D +GY  G+ + + A+++N S +   P  A+++Q  ++ A+      R  +A + 
Sbjct: 181 LSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLP-RAAVVQTQTFMARGARKQKRAVVASLA 239

Query: 227 GAGVKAWRRAQWHEQIL-VPALPQSALPGCSLIHIDYYLQVSLKAP---EATVTLPVFIG 282
           G  V   +RA W  + L +P +  S L  C ++H+DY L+V +  P   +  + LP+ IG
Sbjct: 240 GEPVGPGQRALWQGRALRIPPVGPSIL-HCRVLHVDYALKVCVDIPGTSKLLLELPLVIG 298

Query: 283 NIAVN 287
            I ++
Sbjct: 299 TIPLH 303


>gi|18373305 arrestin domain containing 2 isoform 1 [Homo sapiens]
          Length = 407

 Score =  101 bits (252), Expect = 1e-21
 Identities = 85/308 (27%), Positives = 147/308 (47%), Gaps = 27/308 (8%)

Query: 3   RVQLFEISLSHGRV----VYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVS-----N 53
           +V+ F + L         V+S G+ +AG V + L +     A+R+   G   V      +
Sbjct: 5   KVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRS 64

Query: 54  KANDTAWV------VEEGYFNSSLSLADKG---SLPAGEHSFPFQFLLPATAPTSFEGPF 104
             + TA+       VE     ++L   D G   +LP G H F F F LP T  TSFEG  
Sbjct: 65  AGSSTAYTQSYSERVEVVSHRATLLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKH 124

Query: 105 GKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTG 164
           G + + ++A +H P +    +   VF ++ P+++N+ P +  P   +  K         G
Sbjct: 125 GSVRYCIKATLHRP-WVPARRARKVFTVIEPVDINT-PALLAPQAGAREKVARSWYCNRG 182

Query: 165 SVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVR-TIA 223
            V L+A  D +GY  G+ + + A+++N S +   P  A+++Q  ++ A+      R  +A
Sbjct: 183 LVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLP-RAAVVQTQTFMARGARKQKRAVVA 241

Query: 224 EVEGAGVKAWRRAQWHEQIL-VPALPQSALPGCSLIHIDYYLQVSLKAP---EATVTLPV 279
            + G  V   +RA W  + L +P +  S L  C ++H+DY L+V +  P   +  + LP+
Sbjct: 242 SLAGEPVGPGQRALWQGRALRIPPVGPSIL-HCRVLHVDYALKVCVDIPGTSKLLLELPL 300

Query: 280 FIGNIAVN 287
            IG I ++
Sbjct: 301 VIGTIPLH 308


>gi|190886442 arrestin domain containing 4 [Homo sapiens]
          Length = 418

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 86/292 (29%), Positives = 138/292 (47%), Gaps = 26/292 (8%)

Query: 18  YSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGVS--------NKANDTAWVV--EEGYF 67
           YS GE +AG V +    P+  RA+R+   G    +          A+  A  V  E  Y 
Sbjct: 32  YSSGETVAGHVLLEASEPVALRALRLEAQGRATAAWGPSTCPRASASTAALAVFSEVEYL 91

Query: 68  NSSLSLADKGS------LPAGEHSFPFQFLLPATA-PTSFEGPFGKIVHQVRAAIHTPRF 120
           N  LSL +  +      L  G+H FPF+F LP+    TSF G +G I + VRA +  P+ 
Sbjct: 92  NVRLSLREPPAGEGIILLQPGKHEFPFRFQLPSEPLVTSFTGKYGSIQYCVRAVLERPKV 151

Query: 121 SKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVG 180
             D        ++S +++N+ P +  P + +  K        +G V L+A  + +GY  G
Sbjct: 152 P-DQSVKRELQVVSHVDVNT-PALLTPVLKTQEKMVGCWFFTSGPVSLSAKIERKGYCNG 209

Query: 181 QALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVR-TIAEVEGAGVKAWRRAQWH 239
           +A+ ++A++EN S +   P  A++ Q  +Y A      +R  +A V G  + +     W+
Sbjct: 210 EAIPIYAEIENCSSRLIVP-KAAIFQTQTYLASGKTKTIRHMVANVRGNHIASGSTDTWN 268

Query: 240 EQIL-VPALPQSALPGCSLIHIDYYLQVSLKAPEA---TVTLPVFIGNIAVN 287
            + L +P +  S L  C +I +DY L V +  P A    + LP+ IG I  N
Sbjct: 269 GKTLKIPPVTPSIL-DCCIIRVDYSLAVYIHIPGAKKLMLELPLVIGTIPYN 319


>gi|32698736 arrestin domain containing 3 [Homo sapiens]
          Length = 414

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 83/317 (26%), Positives = 155/317 (48%), Gaps = 34/317 (10%)

Query: 1   MGRVQLFEIS---LSHGRV-VYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGV----- 51
           +G+V+   IS   L+   V VYS G+ ++G V + +   +  +++++   G   V     
Sbjct: 3   LGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTES 62

Query: 52  ----SNKANDTAWVVEEGYFNSSLSL---------ADKG--SLPAGEHSFPFQFLLPATA 96
               SN A    +  E  YFN    L         +++G  ++ +G H + F F LP T 
Sbjct: 63  RNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNSEEGFHTIHSGRHEYAFSFELPQTP 122

Query: 97  -PTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKK 155
             TSFEG  G + + V+A +H P +    K    F +   +++N+ P +  P   +  K 
Sbjct: 123 LATSFEGRHGSVRYWVKAELHRP-WLLPVKLKKEFTVFEHIDINT-PSLLSPQAGTKEKT 180

Query: 156 FSYKLVKTGSVVLTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRW 215
                  +G + L+A  + +GY  G+++Q+ A++EN S +   P  A++ Q  ++ AK  
Sbjct: 181 LCCWFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPK-AAIYQTQAFYAKGK 239

Query: 216 IHDVRT-IAEVEGAGVKAWRRAQWHEQIL-VPALPQSALPGCSLIHIDYYLQVSLKAPEA 273
           + +V+  +A + G  + + +   W+ ++L +P +  S L  CS+I ++Y L V +  P A
Sbjct: 240 MKEVKQLVANLRGESLSSGKTETWNGKLLKIPPVSPSILD-CSIIRVEYSLMVYVDIPGA 298

Query: 274 T---VTLPVFIGNIAVN 287
               + LP+ IG I ++
Sbjct: 299 MDLFLNLPLVIGTIPLH 315


>gi|171184421 thioredoxin interacting protein [Homo sapiens]
          Length = 391

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 79/347 (22%), Positives = 155/347 (44%), Gaps = 36/347 (10%)

Query: 3   RVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGV-----SNKAND 57
           +++ FE+  +    VY  GE +AG V V +      +A+R+   G   V     S +   
Sbjct: 6   KIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQ 65

Query: 58  TAWVVEEGYFNSSLSLADKGS--------LPAGEHSFPFQFLLP-ATAPTSFEGPFGKIV 108
           T+  +    +  +L L D+ +         P  ++ + F F LP     TSF+G +G + 
Sbjct: 66  TSEYLR---YEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVD 122

Query: 109 HQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVL 168
           + V+A +  P      +    F ++  +++N+ PD+  P  A   KK S   +  G V +
Sbjct: 123 YWVKAFLDRPS-QPTQETKKNFEVVDLVDVNT-PDLMAPVSAKKEKKVSCMFIPDGRVSV 180

Query: 169 TASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDV-RTIAEVEG 227
           +A  D +G+  G  + +HAD EN   +   P  A+++ + +Y A      + + ++ V G
Sbjct: 181 SARIDRKGFCEGDEISIHADFENTCSRIVVP-KAAIVARHTYLANGQTKVLTQKLSSVRG 239

Query: 228 AGVKAWRRAQWHEQILVPALPQSALPGCSLIHIDYYLQVSLKAP---EATVTLPVFIGN- 283
             + +   A W  + L     + ++ GC+++ ++Y L + +  P   +  + LP+ IG+ 
Sbjct: 240 NHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSR 299

Query: 284 --IAVNHAPVSPRPG-------LGLP--PGAPPLVVPSAPPQEEAEA 319
             ++   + ++ R         L +P  P APP  +   P     E+
Sbjct: 300 SGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLES 346


>gi|122937478 arrestin domain containing 5 [Homo sapiens]
          Length = 342

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 51/224 (22%), Positives = 89/224 (39%), Gaps = 18/224 (8%)

Query: 1   MGRVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGV--SNKANDT 58
           M  V+  E+ L   R+ Y  G  + G V + L + L    ++V  +G   V  S +A  +
Sbjct: 15  MSVVKSIELVLPEDRI-YLAGSSIKGQVILTLNSTLVDPIVKVELVGRGYVEWSEEAGAS 73

Query: 59  AWVVEEGYFNSSLSLADKGS--------LPAGEHSFPFQFLLPATAPTSFEGPFGKIVHQ 110
                    N+      K          L AG H+F F F LP   P++F   FG + + 
Sbjct: 74  CDYSRNVICNNKADYVHKTKTFPVEDNWLSAGSHTFDFHFNLPPRLPSTFTSKFGHVFYF 133

Query: 111 VRAAIHTPRFSKDH---KCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVV 167
           V+A+       ++H   K  +   +      +     + P    A +K SY   + G+V 
Sbjct: 134 VQASC----MGREHILAKKRMYLLVQGTSTFHKETPFQNPLFVEAEEKVSYNCCRQGTVC 189

Query: 168 LTASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYK 211
           L    +   +  G+ +    ++ NQ+ K    VV +L   + Y+
Sbjct: 190 LQIQMERNTFTPGEKVVFTTEINNQTSKCIKTVVFALYAHIQYE 233


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 49/162 (30%), Positives = 61/162 (37%), Gaps = 15/162 (9%)

Query: 268 LKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLPP----GAPPLVV-----PSAPPQEEAE 318
           L+AP + +T P      ++   P    P L  PP     +PPL       P APP     
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628

Query: 319 AEAAAGGPHFLDPVF-LSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCIS 377
              A   P    P+  L+T S      L   L   P +P P P   +P S P  PP  +S
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP--VS 686

Query: 378 TGATVPYFAEGSGGPVP---TTSTLILPPEYSSWGYPYEAPP 416
             AT P  A  S    P     S    PP   S   P +APP
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/194 (28%), Positives = 72/194 (37%), Gaps = 44/194 (22%)

Query: 264 LQVSLKAPEATVTLPVFIGNIAV-----NHAPVSPRPGLGLPP-------GAPPLVVPSA 311
           LQ SL    + ++ P+ I  +       +H+P +P   L +PP         P L  P A
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528

Query: 312 ----PPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPAS 367
               PP E   +         L P  L T S     P L T    P  P PCP    P+ 
Sbjct: 529 SLTTPPLENLPS---------LAPPPLQTASAPLTTPHLET----PPCPAPCPLQAPPSP 575

Query: 368 HPLHPPLCISTGATVPYFAEGS-------GGPVPTTSTLILPPEYSSWGY---PYEAPPS 417
               PP   S+ AT P  A  +       G P P  S L  PP  +       P +APPS
Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635

Query: 418 YEQSCGGVEPSLTP 431
              S     P L+P
Sbjct: 636 PPAS-----PPLSP 644



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 36/131 (27%), Positives = 46/131 (35%), Gaps = 24/131 (18%)

Query: 289 APVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLAT 348
           AP SP P    PP   P   P++PP   +    +   P    P      S     P+  +
Sbjct: 663 APFSPPPS---PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719

Query: 349 LSSVPGAPEP--CPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYS 406
            +  P AP P   P    P S P  PP+  S  AT          P P    L+  P   
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPM--SPSAT----------PPPRVPPLLAAP--- 764

Query: 407 SWGYPYEAPPS 417
               P + PPS
Sbjct: 765 ----PLQVPPS 771



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 42/144 (29%), Positives = 51/144 (35%), Gaps = 26/144 (18%)

Query: 292 SPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLAT--L 349
           +P P    P  APPL VP +PP     + +A   P                 PLLA   L
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV--------------PPLLAAPPL 766

Query: 350 SSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGS-----GGPVPTTSTLILPPE 404
              P  P   P   SP + P  PP      AT P  A  S      G  P + +  LP  
Sbjct: 767 QVPPSPPASLPM--SPLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822

Query: 405 YSSWGYPYEAPPSYEQSCGGVEPS 428
             +   P +APP        V PS
Sbjct: 823 PLATP-PPQAPPVLAAPLLQVPPS 845


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/180 (29%), Positives = 68/180 (37%), Gaps = 29/180 (16%)

Query: 247 LPQSALPGCSLIHIDYYLQVSLKAP---EATVTLPVFIGNIA-VNHAPVSP------RPG 296
           LP S LP    +H+   L+ S  +P   E+ ++ P      + +  +P+SP       P 
Sbjct: 474 LPASPLP--EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPA 531

Query: 297 LGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAP 356
           L  P   PP   P +PP EE+        P    P  L T       P  A+  S P  P
Sbjct: 532 LETPLSPPPEASPLSPPFEES--------PLSPPPEELPTS-----PPPEASRLSPP--P 576

Query: 357 EPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPP 416
           E  P    P   P+ PP         P F E    P P  S L  PPE S    P E  P
Sbjct: 577 EESPMSPPPEESPMSPP--PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 43/158 (27%), Positives = 56/158 (35%), Gaps = 28/158 (17%)

Query: 271 PEATVTLPVFIGNIAVNHAPVSPRPG---LGLPPGA-----PPLVVPSAPPQEEAEAEAA 322
           PEA+   P F        +P+SP P       PP A     PP   P +PP EE+     
Sbjct: 540 PEASPLSPPF------EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP 593

Query: 323 AGGPHFLDPVFLSTKSHSQRQPLLAT---LSSVPGAPEPCPQDGSPASHPLHPPLCISTG 379
                   P   S  S    +  L+     S +   PE  P    P   P+ PP  +S  
Sbjct: 594 PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653

Query: 380 ATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPS 417
           +           P+P  S L  PPE S    P E  P+
Sbjct: 654 S-----------PLPVVSRLSPPPEESPLSPPPEESPT 680



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 40/148 (27%), Positives = 51/148 (34%), Gaps = 32/148 (21%)

Query: 289  APVSPR--------PGLGLPPGAPP---LVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTK 337
            AP++PR        PGLGL P  PP    + PS P   +     +   P+   P+    +
Sbjct: 2329 APLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ 2388

Query: 338  SHSQRQPLLATLSSVPGAP----EPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPV 393
                         S+P  P       PQ  S +  PL P          P  AE +  P 
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR---------PLSAE-AFCPS 2438

Query: 394  PTTSTLILPPEYSSWGYPYEAPPSYEQS 421
            P T     P        PY  PPS  QS
Sbjct: 2439 PVTPRFQSPD-------PYSRPPSRPQS 2459



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 46/165 (27%), Positives = 59/165 (35%), Gaps = 36/165 (21%)

Query: 289 APVSPRPG---LGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHF--------LDP----VF 333
           +P SP P    + LP    PL+    P  EE +    + GPH         L P      
Sbjct: 705 SPASPPPEDSLMSLPLEESPLL----PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPH 760

Query: 334 LSTKS---HSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSG 390
           LS ++   H   QP    L +VP  P   PQ   P   P    L +S     P+ +    
Sbjct: 761 LSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS---- 816

Query: 391 GPVPTTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPS---LTPE 432
            PVP    L   PE S         P  E+ C    P    L+PE
Sbjct: 817 -PVPEEPCLSPQPEES------HLSPQSEEPCLSPRPEESHLSPE 854



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 46/193 (23%), Positives = 65/193 (33%), Gaps = 38/193 (19%)

Query: 269  KAPEATVTLPVFIGNIAVN------HAPVSPRPG-LGLPP-GAPPLVVPSAPPQEEAEAE 320
            K  E+ +     +G+IA        H  + P+PG LG PP  A P +   +P      + 
Sbjct: 2078 KQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLST 2137

Query: 321  AAAG----------GPHFLDPVFLSTKSHSQRQ----------PLLATLSSVPGAPEPCP 360
            +A G          GP     +FL        Q          P        P AP   P
Sbjct: 2138 SADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYP 2197

Query: 361  QDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQ 420
               SP   P  PP+    GA+      G+G P    +T    P +     P    P  + 
Sbjct: 2198 PYPSPTGAPAQPPM---LGAS---SRPGAGQPGEFHTTPPGTPRHQ----PSTPDPFLKP 2247

Query: 421  SCGGVEPSLTPES 433
             C  ++    PES
Sbjct: 2248 RCPSLDNLAVPES 2260


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 46/174 (26%), Positives = 63/174 (36%), Gaps = 16/174 (9%)

Query: 267 SLKAPEATVTLPVF------IGNIAVNHAPVS---PRPGLGLPPGAPPLVVPSAPPQEEA 317
           S + P  T++ P+       +GN +  H       PRP +  PP  PP   P  PP    
Sbjct: 132 SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPP--PPTPPPPPPPLPPP 189

Query: 318 EAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCIS 377
              ++      + P    TK +    P++A    VP AP P P    P   PL P   +S
Sbjct: 190 LPSSSPIKTPLVSPPGPLTKGNL---PVVAP--PVPCAPPPPPPPPPPTPPPLPPASVLS 244

Query: 378 TGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTP 431
             A  P  A     P+P    L+ P  Y        +P    Q      P L P
Sbjct: 245 DKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP 298



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 53/205 (25%), Positives = 69/205 (33%), Gaps = 32/205 (15%)

Query: 244 VPALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGA 303
           +P LP    PG          Q + + P     LP +         P  P PG+      
Sbjct: 264 LPLLPPCGYPGLKAEPASP-AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSET 322

Query: 304 PPLVVP-----SAPPQEE-AEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGA-- 355
           PP + P      APPQ+  A+A  A   P    P FL  K H +           PGA  
Sbjct: 323 PPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQP-FLQKKRHGR-----------PGAGG 370

Query: 356 ----PEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYP 411
               P P P    PA  P       S  AT     +  GG +   S  I+    S + + 
Sbjct: 371 GKLNPPPAP----PARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFH 426

Query: 412 YE---APPSYEQSCGGVEPSLTPES 433
                 PP   + C  + PS  P S
Sbjct: 427 SVEDFPPPDEYKPCQKIYPSKIPRS 451



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 13/24 (54%), Positives = 13/24 (54%)

Query: 290 PVSPRPGLGLPPGAPPLVVPSAPP 313
           PV P P   LPP  PPL  P  PP
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPP 25


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/153 (28%), Positives = 58/153 (37%), Gaps = 17/153 (11%)

Query: 280 FIGNIAVN--HAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTK 337
           ++GN+++     P S  P   LP   PP++ PS PP     A  A   P  + P  +   
Sbjct: 510 YMGNMSMPPPFVPYSQMPP-PLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMP-- 566

Query: 338 SHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTS 397
                 P L T    PG P      G P   P+ PP  +S+    P     S        
Sbjct: 567 ------PSLPTSVPPPGMPPSLSSAGPP---PVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617

Query: 398 TLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLT 430
            + LPP  S+   P   PP   Q   G+ P LT
Sbjct: 618 VMPLPPLSSATPPPGIPPPGVPQ---GIPPQLT 647



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 49/180 (27%), Positives = 64/180 (35%), Gaps = 22/180 (12%)

Query: 245 PALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAP 304
           P +P S +P          L  SL  P     LP  +           P PG+  PP  P
Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATV-----------PPPGMP-PPVMP 566

Query: 305 PLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGS 364
           P +  S PP     + ++AG P  L P  LS+       P  +  S+ P    P P   S
Sbjct: 567 PSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSS 626

Query: 365 PASHPLHPPLCIS-------TGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPS 417
               P  PP  +        T A VP  +      VP      L P   S+G    APP+
Sbjct: 627 ATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFG---SAPPT 683


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 6/116 (5%)

Query: 290 PVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATL 349
           PV  +P   LPPG      P  P +    +  A GGPH   P     K      P L   
Sbjct: 758 PVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKP----TPQLLPP 813

Query: 350 SSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPT-TSTLILPPE 404
           +  P +P   PQ  +        P  +  G   P     +  PVPT   TL LPPE
Sbjct: 814 TERPMSPRSLPQSPTHRGFAYVLPQPVE-GEVGPAAPGPAPPPVPTAVPTLCLPPE 868



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 52/180 (28%), Positives = 61/180 (33%), Gaps = 30/180 (16%)

Query: 271  PEATVTLPVFI-GNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQE-----------EAE 318
            PE    L V+  G   V   P S + G   PP  PP   P+ PP             E E
Sbjct: 1161 PEPPPPLSVYHNGTGTVRRRPASEQAG---PPELPPPPPPAEPPPTDLAHLPPLPPPEGE 1217

Query: 319  AEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVP----GAPEPCPQDGSP---ASHPLH 371
            A   A  P    PV        Q  P   T   VP    G+PE     G+P   +  P  
Sbjct: 1218 ARKPAKPPVSPKPVLTQPVPKLQGSPT-PTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPP 1276

Query: 372  PPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTP 431
            PP        V     GS GP P  S    PP  ++   P   PPS      G  P+  P
Sbjct: 1277 PPTAPKPVKAVAGLPSGSAGPSPAPSPARQPP--AALAKPPGTPPSL-----GASPAKPP 1329



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 15/26 (57%), Positives = 17/26 (65%)

Query: 301  PGAPPLVVPSAPPQEEAEAEAAAGGP 326
            PGAP L VP+ PP+  A A AAA  P
Sbjct: 1331 PGAPALHVPAKPPRAAAAAAAAAAAP 1356


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/130 (31%), Positives = 48/130 (36%), Gaps = 22/130 (16%)

Query: 290 PVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATL 349
           P    P L LPP   P   P++PP               L P  L+T S      L   L
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPP---------------LSP--LATPSPQAPNALAVHL 435

Query: 350 SSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVP---TTSTLILPPEYS 406
              P +P P P   +P S P  PP  +S  AT P  A  S    P     S    PP   
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493

Query: 407 SWGYPYEAPP 416
           S   P +APP
Sbjct: 494 SATPPPQAPP 503



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 39/140 (27%), Positives = 48/140 (34%), Gaps = 19/140 (13%)

Query: 246 ALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPR--------PGL 297
           A P    P    +H+   LQ     P +    PV          PVSP         P L
Sbjct: 421 ATPSPQAPNALAVHL---LQAPFSPPPSP---PVQAPFSPPASPPVSPSATPPSQAPPSL 474

Query: 298 GLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLAT--LSSVPGA 355
             PP   P   P++PP   +        P    P     K   Q  P LAT  L ++P  
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534

Query: 356 PEPCPQDG--SP-ASHPLHP 372
           P   P     SP AS P+ P
Sbjct: 535 PASFPGQAPFSPSASLPMSP 554


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/130 (31%), Positives = 48/130 (36%), Gaps = 22/130 (16%)

Query: 290 PVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATL 349
           P    P L LPP   P   P++PP               L P  L+T S      L   L
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPP---------------LSP--LATPSPQAPNALAVHL 396

Query: 350 SSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVP---TTSTLILPPEYS 406
              P +P P P   +P S P  PP  +S  AT P  A  S    P     S    PP   
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454

Query: 407 SWGYPYEAPP 416
           S   P +APP
Sbjct: 455 SATPPPQAPP 464



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 39/140 (27%), Positives = 48/140 (34%), Gaps = 19/140 (13%)

Query: 246 ALPQSALPGCSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPR--------PGL 297
           A P    P    +H+   LQ     P +    PV          PVSP         P L
Sbjct: 382 ATPSPQAPNALAVHL---LQAPFSPPPSP---PVQAPFSPPASPPVSPSATPPSQAPPSL 435

Query: 298 GLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLAT--LSSVPGA 355
             PP   P   P++PP   +        P    P     K   Q  P LAT  L ++P  
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495

Query: 356 PEPCPQDG--SP-ASHPLHP 372
           P   P     SP AS P+ P
Sbjct: 496 PASFPGQAPFSPSASLPMSP 515


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 41/131 (31%), Positives = 48/131 (36%), Gaps = 34/131 (25%)

Query: 290 PVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATL 349
           P  P PG G PPG PP      PP           GP    P+ L+   H    P     
Sbjct: 296 PPPPVPGYGPPPGPPP--PQQGPPPPPGPFPPRPPGP-LGPPLTLAPPPHLPGPP----- 347

Query: 350 SSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWG 409
              PGAP P P   +PA  P  PP    T + +P     S GP PT              
Sbjct: 348 ---PGAPPPAPH-VNPAFFP--PP----TNSGMP--TSDSRGPPPTD------------- 382

Query: 410 YPYEAPPSYEQ 420
            PY  PP Y++
Sbjct: 383 -PYGRPPPYDR 392


>gi|7657307 LIM domains containing 1 [Homo sapiens]
          Length = 676

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 57/206 (27%), Positives = 78/206 (37%), Gaps = 31/206 (15%)

Query: 253 PGCSLIHIDYYLQVSLKAPE--ATVTLPVFIGNIAVNHAPVSPR--PGLGLPPGAPPLVV 308
           P C L H DYY  +SL +P+      +   IG    +  P SP   P L  P G  PL  
Sbjct: 171 PSC-LTHGDYYDNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNH 229

Query: 309 PSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSV---PGAPEPCPQDGSP 365
                     +E + GG +      +  +S  +   L +T SS    PG P P  ++G+P
Sbjct: 230 RQLSLSSSRSSEGSLGGQNS----GIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAP 285

Query: 366 ASHPLHP-------PLCIS--TGATVPYFAEGSGGPV----------PTTSTLILPPEYS 406
           A  P+ P       PL +S      +P    G GG V          P       P  Y 
Sbjct: 286 AVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYL 345

Query: 407 SWGYPYEAPPSYEQSCGGVEPSLTPE 432
           S   P  +P   + S  G  P L P+
Sbjct: 346 SSSAPSSSPAGLDGSQQGAVPGLGPK 371


>gi|39812055 arrestin, beta 2 isoform 2 [Homo sapiens]
          Length = 394

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 12/142 (8%)

Query: 73  LADKGSLPAGEHSFPFQFLLPATAPTSF---EGP--FGK---IVHQVRAAIHTPRFSKDH 124
           L D+     G+H+ PF F +P   P S     GP   GK   +  ++RA        K H
Sbjct: 86  LQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSH 145

Query: 125 KCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVGQALQ 184
           K + V  ++  +         QP+ A  T+ F   L+   S+ L AS D   Y  G+ L 
Sbjct: 146 KRNSVRLVIRKVQFAPEKPGPQPS-AETTRHF---LMSDRSLHLEASLDKELYYHGEPLN 201

Query: 185 LHADVENQSGKDTSPVVASLLQ 206
           ++  V N S K    +  S+ Q
Sbjct: 202 VNVHVTNNSTKTVKKIKVSVRQ 223


>gi|4757780 arrestin, beta 2 isoform 1 [Homo sapiens]
          Length = 409

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 12/142 (8%)

Query: 73  LADKGSLPAGEHSFPFQFLLPATAPTSF---EGP--FGK---IVHQVRAAIHTPRFSKDH 124
           L D+     G+H+ PF F +P   P S     GP   GK   +  ++RA        K H
Sbjct: 101 LQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSH 160

Query: 125 KCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVGQALQ 184
           K + V  ++  +         QP+ A  T+ F   L+   S+ L AS D   Y  G+ L 
Sbjct: 161 KRNSVRLVIRKVQFAPEKPGPQPS-AETTRHF---LMSDRSLHLEASLDKELYYHGEPLN 216

Query: 185 LHADVENQSGKDTSPVVASLLQ 206
           ++  V N S K    +  S+ Q
Sbjct: 217 VNVHVTNNSTKTVKKIKVSVRQ 238


>gi|7657465 podocalyxin-like 2 [Homo sapiens]
          Length = 605

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 48/148 (32%), Positives = 61/148 (41%), Gaps = 11/148 (7%)

Query: 261 DYYLQVSLKAPEATVTLPVFIGNIAVNHAPV--SPRPGLGLPPGAPPLVVPSAPPQEEAE 318
           D+ L  S + P AT +     G+ A +   V  S  P L LP   P  V P        E
Sbjct: 205 DFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQE 264

Query: 319 AEA----AAG-GPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSP--ASHPLH 371
           AEA    AAG G  F  P   S ++ +    L      VP  P   PQ  +P  A HP  
Sbjct: 265 AEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPS-FPQTTAPSGAEHPDE 323

Query: 372 PPLCISTGATVPYFAEGSGGPVPTTSTL 399
            PL   T A+ P  A G     P+++TL
Sbjct: 324 DPLGSRTSASSP-LAPGDMELTPSSATL 350


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 4/124 (3%)

Query: 295  PGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPG 354
            PG  L P APPL+  +A       A + A       P    T S S+++  L+   ++  
Sbjct: 927  PGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTP---GTSSDSRQRSPLSDYMNLDF 983

Query: 355  APEPCPQDGSPASHPLHP-PLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSWGYPYE 413
            +    P+ G+P+ HP+      +S  A+ PY           +S+L  PP   + G  Y 
Sbjct: 984  SSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYR 1043

Query: 414  APPS 417
             PP+
Sbjct: 1044 LPPA 1047


>gi|116517292 cut-like 2 [Homo sapiens]
          Length = 1486

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 7/52 (13%)

Query: 264  LQVSLKAPEATVT--LPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPP 313
            L+VSL +P A  +  L + +  +  + AP+SP P     PGAPP  VPSA P
Sbjct: 1391 LEVSLNSPSAASSPGLMMSVSPVPSSSAPISPSP-----PGAPPAKVPSASP 1437



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 15/103 (14%)

Query: 295  PGLGLPPGAPPLVVPSAPPQEEAEA-----------EAAAGGPHFLDPVFLSTKSHSQRQ 343
            PG  LP G+ P   PS  PQ+E+EA           ++A+        V L++ S +   
Sbjct: 1346 PGPLLPGGSTP-DCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASSP 1404

Query: 344  PLLATLSSVPGAP---EPCPQDGSPASHPLHPPLCISTGATVP 383
             L+ ++S VP +     P P    PA  P   P     GA  P
Sbjct: 1405 GLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHP 1447


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 43/148 (29%), Positives = 54/148 (36%), Gaps = 32/148 (21%)

Query: 291 VSPRPGLGLPPGAPPLVVP-------SAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQ 343
           V+P P    PPG P L  P       + PPQ    A  A   P    P      +H Q+ 
Sbjct: 193 VTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQA 249

Query: 344 PLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTG-------ATVPYFAEGSGGPVPTT 396
           P L      P +P P P    P+ HP   PL  S G       A  P   +G  GP    
Sbjct: 250 PALH--PQRPPSPHPPPH---PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 304

Query: 397 STLIL----PPEYSSWGYPYEAPPSYEQ 420
           +  +L    PP+      P+  PP   Q
Sbjct: 305 AGPLLQHPGPPQ------PFGLPPQASQ 326



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 12/92 (13%)

Query: 341 QRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEG---SGGPVPTTS 397
           Q QPL ++ +  PG  +       PAS   HPP  +   A  P FA+     GGP P T 
Sbjct: 439 QSQPLPSSPAQPPGLTQSQNLPPPPAS---HPPTGLHQVAPQPPFAQHPFVPGGPPPIT- 494

Query: 398 TLILPPEYSSWGYPYEAP-PSYEQSCGGVEPS 428
               PP   S   P   P  S +  C G   S
Sbjct: 495 ----PPTCPSTSTPPAGPGTSAQPPCSGAAAS 522


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 43/148 (29%), Positives = 54/148 (36%), Gaps = 32/148 (21%)

Query: 291 VSPRPGLGLPPGAPPLVVP-------SAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQ 343
           V+P P    PPG P L  P       + PPQ    A  A   P    P      +H Q+ 
Sbjct: 747 VTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQA 803

Query: 344 PLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTG-------ATVPYFAEGSGGPVPTT 396
           P L      P +P P P    P+ HP   PL  S G       A  P   +G  GP    
Sbjct: 804 PALH--PQRPPSPHPPPH---PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 858

Query: 397 STLIL----PPEYSSWGYPYEAPPSYEQ 420
           +  +L    PP+      P+  PP   Q
Sbjct: 859 AGPLLQHPGPPQ------PFGLPPQASQ 880



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 12/92 (13%)

Query: 341  QRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEG---SGGPVPTTS 397
            Q QPL ++ +  PG  +       PAS   HPP  +   A  P FA+     GGP P T 
Sbjct: 993  QSQPLPSSPAQPPGLTQSQNLPPPPAS---HPPTGLHQVAPQPPFAQHPFVPGGPPPIT- 1048

Query: 398  TLILPPEYSSWGYPYEAP-PSYEQSCGGVEPS 428
                PP   S   P   P  S +  C G   S
Sbjct: 1049 ----PPTCPSTSTPPAGPGTSAQPPCSGAAAS 1076


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 43/148 (29%), Positives = 54/148 (36%), Gaps = 32/148 (21%)

Query: 291 VSPRPGLGLPPGAPPLVVP-------SAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQ 343
           V+P P    PPG P L  P       + PPQ    A  A   P    P      +H Q+ 
Sbjct: 747 VTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQA 803

Query: 344 PLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTG-------ATVPYFAEGSGGPVPTT 396
           P L      P +P P P    P+ HP   PL  S G       A  P   +G  GP    
Sbjct: 804 PALH--PQRPPSPHPPPH---PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ 858

Query: 397 STLIL----PPEYSSWGYPYEAPPSYEQ 420
           +  +L    PP+      P+  PP   Q
Sbjct: 859 AGPLLQHPGPPQ------PFGLPPQASQ 880



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 12/92 (13%)

Query: 341  QRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEG---SGGPVPTTS 397
            Q QPL ++ +  PG  +       PAS   HPP  +   A  P FA+     GGP P T 
Sbjct: 993  QSQPLPSSPAQPPGLTQSQNLPPPPAS---HPPTGLHQVAPQPPFAQHPFVPGGPPPIT- 1048

Query: 398  TLILPPEYSSWGYPYEAP-PSYEQSCGGVEPS 428
                PP   S   P   P  S +  C G   S
Sbjct: 1049 ----PPTCPSTSTPPAGPGTSAQPPCSGAAAS 1076


>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
          Length = 873

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 32/160 (20%)

Query: 255 CSLIHIDYYLQVSLKAPEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPP- 313
           CS+  I   +  S+   E     PV +        P S  P LG+PP +PP+V+ +  P 
Sbjct: 340 CSVTKIPTPVPKSIPISETPNIPPVSV------QPPASIGPPLGVPPRSPPMVMTNRGPV 393

Query: 314 ----------QEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDG 363
                      ++       G PH       S  +     P+L  +   PG     P++ 
Sbjct: 394 PLPIFMEQQIMQQIRPPFIRGPPH-----HASNPNSPLSNPMLPGIGPPPGG----PRNL 444

Query: 364 SPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPP 403
            P S P+H P+        P+    S   +P     +LPP
Sbjct: 445 GPTSSPMHRPM------LSPHIHPPSTPTMPGNPPGLLPP 478


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 38/130 (29%), Positives = 47/130 (36%), Gaps = 29/130 (22%)

Query: 278  PVFIGNIAVNHAPVSPRP-GLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLST 336
            P  +  +AV  A V P P G G PPG       S  P E+     +  GP          
Sbjct: 1011 PPAVHGLAVAPASVVPAPAGSGAPPG-------SLGPSEQIGQAGSTAGPQ--------- 1054

Query: 337  KSHSQRQPLLATLSSV--PGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVP 394
                Q+QP  A       PG P P P   SP  +   PP      + +P    GSG P  
Sbjct: 1055 ----QQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP------SMMPGAVPGSGHPGV 1104

Query: 395  TTSTLILPPE 404
                  LPP+
Sbjct: 1105 ADPGTPLPPD 1114


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 33/115 (28%), Positives = 39/115 (33%), Gaps = 8/115 (6%)

Query: 270 APEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFL 329
           AP   +  P F+G      A   P P    PP AP    P+A P     A A    P   
Sbjct: 233 APGTVIQTPPFVG------AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPG- 285

Query: 330 DPVFLSTKSHSQRQPLLATLSSVPG-APEPCPQDGSPASHPLHPPLCISTGATVP 383
            P    T + +   P  A      G AP P P  G PA     P    +  A  P
Sbjct: 286 HPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 45/165 (27%), Positives = 58/165 (35%), Gaps = 34/165 (20%)

Query: 269 KAPEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQ--EEAEAEAAAGGP 326
           + PE        +GN  V+ +P       G  P AP    P A P+      A    GGP
Sbjct: 46  RTPEVRAAAAGALGNHVVSGSPAG---AAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102

Query: 327 HFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFA 386
               P        S R+PL      VP  P P      PA+  L PP         P  +
Sbjct: 103 QRPGP-------PSPRRPL------VPAGPAP------PAA-KLRPP---------PEGS 133

Query: 387 EGSGGPVPTTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTP 431
            GS  PVP  + +   PE +  G    A P+   +  G  P   P
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 43/144 (29%), Positives = 55/144 (38%), Gaps = 16/144 (11%)

Query: 293 PRPGLGLP--PGAPPLVVPSAPPQEEAEAEAAA-----GGPHFLDPVFLSTKSHS--QRQ 343
           P PG G P  PGA   +  SA       A A A      GP  L P+       +  Q  
Sbjct: 182 PGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTP 241

Query: 344 PLL-ATLSSVPGAPEP--CPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLI 400
           P + A     P AP P   P   +PA+ P  PP   +T A  P    G     PT +  +
Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP----GHPAGPPTAAPAV 297

Query: 401 LPPEYSSWGYPYEAPPSYEQSCGG 424
            PP  +  G    A P+   + GG
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGG 321



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 32/133 (24%), Positives = 42/133 (31%), Gaps = 10/133 (7%)

Query: 271 PEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLD 330
           PE     P      A   A   P PG G  PG  P   P  P        A  G    L+
Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP--GPGKP--------AGPGAAQTLN 199

Query: 331 PVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSG 390
                  SH    P ++ +++ P A  P P+  +P +    PP   +     P       
Sbjct: 200 GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA 259

Query: 391 GPVPTTSTLILPP 403
            P P       PP
Sbjct: 260 APAPAAPAAAPPP 272


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 293  PRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLATLSSV 352
            P+ G G+P GA P  V  AP +  A+ EA AG    L    L  +  +  Q + A + S 
Sbjct: 1036 PQSGEGVPQGAAPEGVSEAPAEAGADREAPAGCRVSLRA--LPGRVSASTQIMRALMGSK 1093

Query: 353  PGAPEPCPQDGSPASHPLHPPLCISTGATVPYFA 386
             G P   P+     S P+   L  S GA +   A
Sbjct: 1094 QGRPSSVPE----VSRPMARRLSCSAGALITCLA 1123


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 43/143 (30%), Positives = 53/143 (37%), Gaps = 35/143 (24%)

Query: 278  PVFIGNIAVNHAPVSPRP-GLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLST 336
            P  +  +AV  A V P P G G PPG       S  P E+     +  GP          
Sbjct: 980  PPAVHGLAVAPASVVPAPAGSGAPPG-------SLGPSEQIGQAGSTAGPQ--------- 1023

Query: 337  KSHSQRQPLLATLSSV--PGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGP-V 393
                Q+QP  A       PG P P P   SP  +   PP      + +P    GSG P V
Sbjct: 1024 ----QQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPP------SMMPGAVPGSGHPGV 1073

Query: 394  PTTSTLILPPEYSSWGYPYEAPP 416
               + L LP     +G P   PP
Sbjct: 1074 AGNAPLGLP-----FGMPPPPPP 1091


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 36.6 bits (83), Expect = 0.046
 Identities = 40/145 (27%), Positives = 54/145 (37%), Gaps = 10/145 (6%)

Query: 290  PVSPRP-GLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLLAT 348
            P +P P G   PP A P   PS        +   A  P  + P   S K      P    
Sbjct: 977  PATPSPKGAPTPPAATP---PSPKGGPATPSPKGAPTPPAVTPP--SPKGSPAATPFPKG 1031

Query: 349  LSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTLILPPEYSSW 408
             S+ P A  P P+ GSPA+ PL      +  AT+P      GGP   +      P  ++ 
Sbjct: 1032 ASTPPAATPPSPK-GSPAATPLPKGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATP 1087

Query: 409  GYPYEAPPSYEQSCGGVEPSLTPES 433
              P   P +       + P+ TP S
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPS 1112



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 35/143 (24%), Positives = 57/143 (39%), Gaps = 11/143 (7%)

Query: 267  SLKAPEATVTLPVFIGNIAVNHAPVSP--RPGLGLPPGA---PPLVVPSAPPQEEAEAEA 321
            ++ +P+   T P  I  ++   AP +P  R G   P      PP V P +  +  A + A
Sbjct: 1394 AIPSPKGDPTSPAVIP-LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS-A 1451

Query: 322  AAGGPHFL----DPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCIS 377
              GGP       DP   +    S ++P      +   +P+  P   +P   P  P +  S
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511

Query: 378  TGATVPYFAEGSGGPVPTTSTLI 400
            +   VP        P+  T+TL+
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLL 1534



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 45/150 (30%), Positives = 54/150 (36%), Gaps = 22/150 (14%)

Query: 290  PVSPRPGLGLPP--GAP-PLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQPLL 346
            P S + GL  PP  GAP P VV    P+         GGP    P    T       P  
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPK---------GGPATSPPKGAPT-------PPA 1314

Query: 347  ATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGP-VPTTSTLILPPEY 405
            AT  S  G+P   P  G+P    + PP    T           GGP  P++     PP  
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374

Query: 406  --SSWGYPYEAPPSYEQSCGGVEPSLTPES 433
              S  G P   PPS ++      P   P S
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 39/170 (22%), Positives = 56/170 (32%), Gaps = 36/170 (21%)

Query: 270  APEATVTLPVFIGNIAVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAA------ 323
            AP AT+        +A   A + P   +  P   P +  P   P   +  EA++      
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587

Query: 324  ----GGPH----FLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLC 375
                G P      + P   S        P   T    P +PE  P   +P   P  PP+ 
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT----PPSPEKGPATPAPKGTPTSPPVT 1643

Query: 376  IST---------------GATVPYFAEG---SGGPVPTTSTLILPPEYSS 407
             S+               GATVP  ++G     GP      L+ P   S+
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693



 Score = 32.3 bits (72), Expect = 0.86
 Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 23/154 (14%)

Query: 290  PVSPRPGLGLPP--GAP--PLVVPSAP------PQEEAEAEAAAGGPHFLDPVFLSTKSH 339
            P SP+ GL  P   GAP  P   P +P      P  +      A  P        +    
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238

Query: 340  SQRQPLLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEGSGGPVPTTSTL 399
                   AT  S  G P   P  G+P      PP      AT P+     G P P    +
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH----KGAPNP---AV 1291

Query: 400  ILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTPES 433
            + PP  S  G P  +PP    +     P+ TP S
Sbjct: 1292 VTPP--SPKGGPATSPPKGAPT----PPAATPPS 1319



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 16/40 (40%), Positives = 20/40 (50%)

Query: 326 PHFLDPVFLSTKSHSQRQPLLATLSSVPGAPEPCPQDGSP 365
           P     V L+ K+H  ++  L TL  VP A E CP   SP
Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP 714



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 21/159 (13%)

Query: 285  AVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGP---HFLDPVFLSTKSHSQ 341
            A N A V+P    G P  +PP   P+ P       + + G P       P  ++  S   
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 342  RQPLLATLSSVPGAP-EPCPQDG--SPASHPLH---PPLCISTGATVPYFAEGSGGPVPT 395
               L AT  S  G P  P  ++G   PA+ P H   P +   +    P      G P   
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP--- 1402

Query: 396  TSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPS---LTP 431
            TS  ++P        P +AP +     G   PS   LTP
Sbjct: 1403 TSPAVIPLS------PKKAPATPVTREGAATPSKGDLTP 1435



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 37/150 (24%), Positives = 55/150 (36%), Gaps = 15/150 (10%)

Query: 285 AVNHAPVSPRPGLGLPPGAPPLVVPSAPPQEEAEAEAAAGGPHFLDPVFLSTKSHSQRQP 344
           A  + PV+P P     P A  ++ P  P    + +   AG P     V     SH+    
Sbjct: 704 ASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV--DGISHT---- 757

Query: 345 LLATLSSVPGAPEPCPQDGSPASHPLHPPLCISTGATVPYFAEG-SGGPVPTTSTLILPP 403
             + L+ V  +P+ CP + S AS         S+  T+ Y A+  S   V  +     PP
Sbjct: 758 --SALAPVASSPKECPTEDSGAS------ATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809

Query: 404 EYSSWGYPYEAPPSYEQSCGGVEPSLTPES 433
                  P     +       VE S  PE+
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPEN 839



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 48/172 (27%), Positives = 59/172 (34%), Gaps = 36/172 (20%)

Query: 290  PVSPRPGLGLPP--GAP--PLVVP-------SAPPQEEAEAEAAAGGPHFLDPVFLSTKS 338
            P SP+ GL  PP  GAP  P   P       + PP + A    AA  P     +      
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169

Query: 339  HSQRQPL---------LATLS-----SVPGAPEPCPQDGSPASHPLHPPLCISTGATVPY 384
             +   P          LAT S     + P A  P P+ G     P   P   +  AT P 
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPS 1227

Query: 385  FAEGSGGPVP---TTSTLILPPEYSSWGYPYEAPPSYEQSCGGVEPSLTPES 433
               G   P P    T+    PP  S  G P   PP    +     P+ TP S
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPP--SPKGGPATPPPKGAPT----PPAATPPS 1273


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,867,135
Number of Sequences: 37866
Number of extensions: 1212336
Number of successful extensions: 7313
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 465
Number of HSP's that attempted gapping in prelim test: 6145
Number of HSP's gapped (non-prelim): 1377
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press