Search of human proteins with 226442991

Search of human proteins with 226442991

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226442991 jumonji, AT rich interactive domain 1D isoform 1
[Homo sapiens]
         (1570 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H...  3194   0.0  
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho...  3116   0.0  
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H...  2896   0.0  
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H...  2651   0.0  
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H...  2312   0.0  
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa...  1447   0.0  
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa...  1447   0.0  
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]    1303   0.0  
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ...  1104   0.0  
gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]           144   9e-34
gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]           144   9e-34
gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]           143   1e-33
gi|39653317 jumonji domain containing 2D [Homo sapiens]               139   2e-32
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]           138   4e-32
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]           138   4e-32
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]           138   4e-32
gi|98986459 jumonji domain containing 2A [Homo sapiens]               137   8e-32
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]    131   4e-30
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]    131   4e-30
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]    131   4e-30
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]    131   4e-30
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ...   131   4e-30
gi|45504380 jumonji domain containing 2B [Homo sapiens]               130   1e-29
gi|221139764 PHD and ring finger domains 1 [Homo sapiens]              70   1e-11
gi|205830434 D4, zinc and double PHD fingers family 1 isoform c ...    67   1e-10
gi|205830430 D4, zinc and double PHD fingers family 1 isoform a ...    67   1e-10
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo...    66   2e-10
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    66   2e-10
gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]     65   4e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    64   1e-09

>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
            sapiens]
          Length = 1570

 Score = 3194 bits (8282), Expect = 0.0
 Identities = 1570/1570 (100%), Positives = 1570/1570 (100%)

Query: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60
            MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV
Sbjct: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60

Query: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI 120
            DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI
Sbjct: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI 120

Query: 121  EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP 180
            EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP
Sbjct: 121  EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP 180

Query: 181  FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG 240
            FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG
Sbjct: 181  FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG 240

Query: 241  PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM 300
            PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM
Sbjct: 241  PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM 300

Query: 301  QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK 360
            QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK
Sbjct: 301  QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK 360

Query: 361  CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS 420
            CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS
Sbjct: 361  CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS 420

Query: 421  SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPW 480
            SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPW
Sbjct: 421  SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPW 480

Query: 481  PPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 540
            PPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW
Sbjct: 481  PPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 540

Query: 541  SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH 600
            SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH
Sbjct: 541  SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH 600

Query: 601  GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY 660
            GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY
Sbjct: 601  GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY 660

Query: 661  CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL 720
            CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL
Sbjct: 661  CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL 720

Query: 721  LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM 780
            LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM
Sbjct: 721  LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM 780

Query: 781  LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL 840
            LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL
Sbjct: 781  LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL 840

Query: 841  SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA 900
            SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA
Sbjct: 841  SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA 900

Query: 901  YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA 960
            YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA
Sbjct: 901  YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA 960

Query: 961  HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL 1020
            HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL
Sbjct: 961  HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL 1020

Query: 1021 EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP 1080
            EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP
Sbjct: 1021 EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP 1080

Query: 1081 VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA 1140
            VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA
Sbjct: 1081 VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA 1140

Query: 1141 LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS 1200
            LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS
Sbjct: 1141 LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS 1200

Query: 1201 SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF 1260
            SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF
Sbjct: 1201 SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF 1260

Query: 1261 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT 1320
            LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT
Sbjct: 1261 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT 1320

Query: 1321 ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN 1380
            ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN
Sbjct: 1321 ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN 1380

Query: 1381 MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA 1440
            MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA
Sbjct: 1381 MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA 1440

Query: 1441 GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS 1500
            GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS
Sbjct: 1441 GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS 1500

Query: 1501 SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL 1560
            SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL
Sbjct: 1501 SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL 1560

Query: 1561 QLSYSDEQQL 1570
            QLSYSDEQQL
Sbjct: 1561 QLSYSDEQQL 1570


>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
            sapiens]
          Length = 1539

 Score = 3116 bits (8078), Expect = 0.0
 Identities = 1539/1570 (98%), Positives = 1539/1570 (98%), Gaps = 31/1570 (1%)

Query: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60
            MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV
Sbjct: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60

Query: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI 120
            DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI
Sbjct: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI 120

Query: 121  EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP 180
            EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP
Sbjct: 121  EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP 180

Query: 181  FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG 240
            FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG
Sbjct: 181  FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG 240

Query: 241  PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM 300
            PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM
Sbjct: 241  PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM 300

Query: 301  QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK 360
            QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK
Sbjct: 301  QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK 360

Query: 361  CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS 420
            CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS
Sbjct: 361  CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS 420

Query: 421  SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPW 480
            SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEK                       
Sbjct: 421  SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEK----------------------- 457

Query: 481  PPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 540
                    EYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW
Sbjct: 458  --------EYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 509

Query: 541  SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH 600
            SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH
Sbjct: 510  SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH 569

Query: 601  GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY 660
            GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY
Sbjct: 570  GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY 629

Query: 661  CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL 720
            CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL
Sbjct: 630  CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL 689

Query: 721  LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM 780
            LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM
Sbjct: 690  LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM 749

Query: 781  LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL 840
            LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL
Sbjct: 750  LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL 809

Query: 841  SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA 900
            SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA
Sbjct: 810  SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA 869

Query: 901  YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA 960
            YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA
Sbjct: 870  YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA 929

Query: 961  HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL 1020
            HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL
Sbjct: 930  HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL 989

Query: 1021 EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP 1080
            EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP
Sbjct: 990  EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP 1049

Query: 1081 VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA 1140
            VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA
Sbjct: 1050 VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA 1109

Query: 1141 LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS 1200
            LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS
Sbjct: 1110 LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS 1169

Query: 1201 SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF 1260
            SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF
Sbjct: 1170 SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF 1229

Query: 1261 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT 1320
            LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT
Sbjct: 1230 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT 1289

Query: 1321 ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN 1380
            ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN
Sbjct: 1290 ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN 1349

Query: 1381 MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA 1440
            MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA
Sbjct: 1350 MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA 1409

Query: 1441 GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS 1500
            GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS
Sbjct: 1410 GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS 1469

Query: 1501 SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL 1560
            SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL
Sbjct: 1470 SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL 1529

Query: 1561 QLSYSDEQQL 1570
            QLSYSDEQQL
Sbjct: 1530 QLSYSDEQQL 1539


>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
            sapiens]
          Length = 1482

 Score = 2896 bits (7507), Expect = 0.0
 Identities = 1452/1570 (92%), Positives = 1460/1570 (92%), Gaps = 88/1570 (5%)

Query: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60
            MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV
Sbjct: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60

Query: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI 120
            DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSK   
Sbjct: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSK--- 117

Query: 121  EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP 180
                    C    +    +   Y P                               ++ P
Sbjct: 118  -------QCNTHPFDNEVKDKEYKP-------------------------------HSIP 139

Query: 181  FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG 240
                V+  ++  +S                RRAKRLQPDPEPTEEDIEKHPELKKLQIYG
Sbjct: 140  LRQSVQPSKFSSYS----------------RRAKRLQPDPEPTEEDIEKHPELKKLQIYG 183

Query: 241  PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM 300
            PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM
Sbjct: 184  PGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTM 243

Query: 301  QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK 360
            QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK
Sbjct: 244  QLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPK 303

Query: 361  CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS 420
            CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS
Sbjct: 304  CILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVS 363

Query: 421  SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPW 480
            SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEK                       
Sbjct: 364  SIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEK----------------------- 400

Query: 481  PPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 540
                    EYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW
Sbjct: 401  --------EYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 452

Query: 541  SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH 600
            SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH
Sbjct: 453  SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSH 512

Query: 601  GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY 660
            GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY
Sbjct: 513  GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY 572

Query: 661  CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL 720
            CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL
Sbjct: 573  CVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFEL 632

Query: 721  LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM 780
            LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM
Sbjct: 633  LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTM 692

Query: 781  LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL 840
            LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL
Sbjct: 693  LHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCL 752

Query: 841  SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA 900
            SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA
Sbjct: 753  SEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEA 812

Query: 901  YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA 960
            YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA
Sbjct: 813  YQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSA 872

Query: 961  HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL 1020
            HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL
Sbjct: 873  HRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATL 932

Query: 1021 EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP 1080
            EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP
Sbjct: 933  EAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLP 992

Query: 1081 VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA 1140
            VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA
Sbjct: 993  VGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKA 1052

Query: 1141 LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS 1200
            LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS
Sbjct: 1053 LGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMAS 1112

Query: 1201 SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF 1260
            SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF
Sbjct: 1113 SPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKF 1172

Query: 1261 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT 1320
            LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT
Sbjct: 1173 LCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVT 1232

Query: 1321 ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN 1380
            ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN
Sbjct: 1233 ALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPEN 1292

Query: 1381 MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA 1440
            MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA
Sbjct: 1293 MAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQA 1352

Query: 1441 GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS 1500
            GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS
Sbjct: 1353 GQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARS 1412

Query: 1501 SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL 1560
            SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL
Sbjct: 1413 SGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLL 1472

Query: 1561 QLSYSDEQQL 1570
            QLSYSDEQQL
Sbjct: 1473 QLSYSDEQQL 1482


>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
            sapiens]
          Length = 1560

 Score = 2651 bits (6871), Expect = 0.0
 Identities = 1323/1583 (83%), Positives = 1411/1583 (89%), Gaps = 55/1583 (3%)

Query: 1    MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60
            MEPG D+FLPPPECPVFEPSWAEF+DPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV
Sbjct: 1    MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 60

Query: 61   DNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVI 120
            DNFRFTPR+QRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVER+ILDLYSLSKIV+
Sbjct: 61   DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 120

Query: 121  EEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP 180
            EEGGYEAICKDRRWARVAQRL+YPPGKNIGSLLRSHYERI+YPYEM+QSGAN VQCNT P
Sbjct: 121  EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 180

Query: 181  FDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYG 240
            FDNE KDKEYKPHSIPLRQSVQPSKF+SY RRAKRLQPDPEPTEEDIEK+PELKKLQIYG
Sbjct: 181  FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 240

Query: 241  PGPKMMGLGLMAKDKDKTVHKK----VTCPPTVTVKDEQSGGGNVSSTLLKQHL------ 290
             GPKMMGLGLMA  KDKT+ KK      CPPTV VK+E  G   V ST  K  L      
Sbjct: 241  AGPKMMGLGLMA--KDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEEL 298

Query: 291  --SLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPL 348
              S EPCTK TM+LR+NHS+AQFI+SY+C++CSRGDEDDKLL CDGCDDNYHIFCLLPPL
Sbjct: 299  SHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPL 358

Query: 349  PEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPT 408
            PEIP+G+WRCPKC++AECK+PPEAFGFEQAT+EY+LQSFGEMADSFK+DYFNMPVHMVPT
Sbjct: 359  PEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPT 418

Query: 409  ELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLI 468
            ELVEKEFWRLV+SIEEDVTVEYGADIHSKEFGSGFPVS+SK++L+PEE            
Sbjct: 419  ELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEE------------ 466

Query: 469  SSFWAQAVLPPWPPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMV 528
                               +EYATSGWNLNVMPVL+QSVLCHINADISGMKVPWLYVGMV
Sbjct: 467  -------------------EEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMV 507

Query: 529  FSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQL 588
            FSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMK LTPELFDSQPDLLHQL
Sbjct: 508  FSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQL 567

Query: 589  VTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
            VTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR
Sbjct: 568  VTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 627

Query: 649  QCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEK 708
            QCIEHYRRLRRYCVFSHEELICKMAA PE LDLNLA AVHKEMFIMVQEERRLRKALLEK
Sbjct: 628  QCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEK 687

Query: 709  GVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYL 768
            G+TEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYL
Sbjct: 688  GITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYL 747

Query: 769  RYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFP 828
            RYRYTLDELP MLHKLK+RAESFDTWANKVRVALEVEDGRKRS EELRALESEARERRFP
Sbjct: 748  RYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFP 807

Query: 829  NSELLQRLKNCLSEVEACIAQVLGLVSGQVA---RMDTPQLTLTELRVLLEQMGSLPCAM 885
            NSELLQ+LKNCLSE EAC+++ LGLVSGQ A   R+   Q+TLTELR  L+QM +LPCAM
Sbjct: 808  NSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVAGLQMTLTELRAFLDQMNNLPCAM 867

Query: 886  HQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQ 945
            HQIGDVK VLEQVEAYQAEAREALA+LPSSPGLL+SLLERG+QLGVEVPEA QLQ+QVEQ
Sbjct: 868  HQIGDVKGVLEQVEAYQAEAREALASLPSSPGLLQSLLERGRQLGVEVPEAQQLQRQVEQ 927

Query: 946  AQWLDEVKQALAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKA 1005
            A+WLDEVK+ LAPSA RG+L +M+GLLV GA +A SP+VDKA+AELQELLTIAERWEEKA
Sbjct: 928  ARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKA 987

Query: 1006 HFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPC 1065
            H CLEARQKHPPATLEAIIRE ENIPVHLPNIQALKEAL KA+AWIADVDEIQNGDHYPC
Sbjct: 988  HLCLEARQKHPPATLEAIIREAENIPVHLPNIQALKEALAKARAWIADVDEIQNGDHYPC 1047

Query: 1066 LDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCAD 1125
            LDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCAD
Sbjct: 1048 LDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCAD 1107

Query: 1126 AGSDSTKRSRWMEKALGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRT 1185
            AGSDSTKRSRWMEK LGLY+ DTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRT
Sbjct: 1108 AGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRT 1167

Query: 1186 NSAKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSL 1245
            NSAKPSPLA S  ASS TSICVCGQV AG G LQCDLCQDWFHG+CVSVP LL+SP+P+ 
Sbjct: 1168 NSAKPSPLASSSTASSTTSICVCGQVLAGAGALQCDLCQDWFHGRCVSVPRLLSSPRPNP 1227

Query: 1246 TSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIG 1305
            TSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAI 
Sbjct: 1228 TSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIS 1287

Query: 1306 WQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKV 1365
            WQ RAR+ALASEDVTALL +LAELRQ+LQA+PRPEE   Y +A A DP+REGSG ++ KV
Sbjct: 1288 WQGRARQALASEDVTALLGRLAELRQRLQAEPRPEEPPNYPAAPASDPLREGSGKDMPKV 1347

Query: 1366 QGLLENGDSVTSPENMAPGKGS---DLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGD 1422
            QGLLENGDSVTSPE +AP +GS   DLELLSSLLPQLTGPVLELPEA RAPLEELMMEGD
Sbjct: 1348 QGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLLPQLTGPVLELPEATRAPLEELMMEGD 1407

Query: 1423 LLEVTLDENHSIWQLLQAGQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQG 1482
            LLEVTLDENHSIWQLLQAGQPPDL+RIRTLLELEK E  GSR R RALERRRRR KVD+G
Sbjct: 1408 LLEVTLDENHSIWQLLQAGQPPDLERIRTLLELEKAERHGSRARGRALERRRRR-KVDRG 1466

Query: 1483 RNVENLVQQELQSKRARSSGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSL 1542
               ++  ++EL+ KR RSSG  ++  +EEE  +E+   E       T  SP  + NQN L
Sbjct: 1467 GEGDDPAREELEPKRVRSSGPEAEEVQEEEELEEETGGEGPPAPIPTTGSPSTQENQNGL 1526

Query: 1543 QHKD---SGSSAACPSLMPLLQL 1562
            +  +   SG SA   +L P L L
Sbjct: 1527 EPAEGTTSGPSAPFSTLTPRLHL 1549


>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
            sapiens]
          Length = 1379

 Score = 2312 bits (5992), Expect = 0.0
 Identities = 1143/1332 (85%), Positives = 1211/1332 (90%), Gaps = 48/1332 (3%)

Query: 118  IVIEEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCN 177
            IV+EEGGYEAICKDRRWARVAQRL+YPPGKNIGSLLRSHYERI+YPYEM+QSGAN VQCN
Sbjct: 51   IVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCN 110

Query: 178  THPFDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQ 237
            T PFDNE KDKEYKPHSIPLRQSVQPSKF+SY RRAKRLQPDPEPTEEDIEK+PELKKLQ
Sbjct: 111  TRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQ 170

Query: 238  IYGPGPKMMGLGLMAKDKDKTVHKK----VTCPPTVTVKDEQSGGGNVSSTLLKQHL--- 290
            IYG GPKMMGLGLMAKDK  T+ KK      CPPTV VK+E  G   V ST  K  L   
Sbjct: 171  IYGAGPKMMGLGLMAKDK--TLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESK 228

Query: 291  -----SLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLL 345
                 S EPCTK TM+LR+NHS+AQFI+SY+C++CSRGDEDDKLL CDGCDDNYHIFCLL
Sbjct: 229  EELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLL 288

Query: 346  PPLPEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHM 405
            PPLPEIP+G+WRCPKC++AECK+PPEAFGFEQAT+EY+LQSFGEMADSFK+DYFNMPVHM
Sbjct: 289  PPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHM 348

Query: 406  VPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLT 465
            VPTELVEKEFWRLV+SIEEDVTVEYGADIHSKEFGSGFPVS+SK++L+PEE         
Sbjct: 349  VPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEE--------- 399

Query: 466  RLISSFWAQAVLPPWPPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYV 525
                                  +EYATSGWNLNVMPVL+QSVLCHINADISGMKVPWLYV
Sbjct: 400  ----------------------EEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYV 437

Query: 526  GMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLL 585
            GMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMK LTPELFDSQPDLL
Sbjct: 438  GMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLL 497

Query: 586  HQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLP 645
            HQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLP
Sbjct: 498  HQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLP 557

Query: 646  AGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKAL 705
            AGRQCIEHYRRLRRYCVFSHEELICKMAA PE LDLNLA AVHKEMFIMVQEERRLRKAL
Sbjct: 558  AGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKAL 617

Query: 706  LEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSR 765
            LEKG+TEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSR
Sbjct: 618  LEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSR 677

Query: 766  QYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARER 825
            QYLRYRYTLDELP MLHKLK+RAESFDTWANKVRVALEVEDGRKRS EELRALESEARER
Sbjct: 678  QYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARER 737

Query: 826  RFPNSELLQRLKNCLSEVEACIAQVLGLVSGQVA---RMDTPQLTLTELRVLLEQMGSLP 882
            RFPNSELLQ+LKNCLSE EAC+++ LGLVSGQ A   R+   Q+TLTELR  L+QM +LP
Sbjct: 738  RFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVAGLQMTLTELRAFLDQMNNLP 797

Query: 883  CAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQ 942
            CAMHQIGDVK VLEQVEAYQAEAREALA+LPSSPGLL+SLLERG+QLGVEVPEA QLQ+Q
Sbjct: 798  CAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLLQSLLERGRQLGVEVPEAQQLQRQ 857

Query: 943  VEQAQWLDEVKQALAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWE 1002
            VEQA+WLDEVK+ LAPSA RG+L +M+GLLV GA +A SP+VDKA+AELQELLTIAERWE
Sbjct: 858  VEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWE 917

Query: 1003 EKAHFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDH 1062
            EKAH CLEARQKHPPATLEAIIRE ENIPVHLPNIQALKEAL KA+AWIADVDEIQNGDH
Sbjct: 918  EKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQALKEALAKARAWIADVDEIQNGDH 977

Query: 1063 YPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCP 1122
            YPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCP
Sbjct: 978  YPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCP 1037

Query: 1123 CADAGSDSTKRSRWMEKALGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQL 1182
            CADAGSDSTKRSRWMEK LGLY+ DTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQL
Sbjct: 1038 CADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQL 1097

Query: 1183 RRTNSAKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPK 1242
            RRTNSAKPSPLA S  ASS TSICVCGQV AG G LQCDLCQDWFHG+CVSVP LL+SP+
Sbjct: 1098 RRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQCDLCQDWFHGRCVSVPRLLSSPR 1157

Query: 1243 PSLTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTER 1302
            P+ TSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTER
Sbjct: 1158 PNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTER 1217

Query: 1303 AIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNI 1362
            AI WQ RAR+ALASEDVTALL +LAELRQ+LQA+PRPEE   Y +A A DP+REGSG ++
Sbjct: 1218 AISWQGRARQALASEDVTALLGRLAELRQRLQAEPRPEEPPNYPAAPASDPLREGSGKDM 1277

Query: 1363 SKVQGLLENGDSVTSPENMAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGD 1422
             KVQGLLENGDSVTSPE +AP +GSDLELLSSLLPQLTGPVLELPEA RAPLEELMMEGD
Sbjct: 1278 PKVQGLLENGDSVTSPEKVAPEEGSDLELLSSLLPQLTGPVLELPEATRAPLEELMMEGD 1337

Query: 1423 LLEVTLDENHSI 1434
            LLEVTLDENHSI
Sbjct: 1338 LLEVTLDENHSI 1349



 Score =  107 bits (267), Expect = 9e-23
 Identities = 47/50 (94%), Positives = 49/50 (98%)

Query: 1  MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPA 50
          MEPG D+FLPPPECPVFEPSWAEF+DPLGYIAKIRPIAEKSGICKIRPPA
Sbjct: 1  MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPA 50


>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
            sapiens]
          Length = 1690

 Score = 1447 bits (3747), Expect = 0.0
 Identities = 735/1361 (54%), Positives = 948/1361 (69%), Gaps = 93/1361 (6%)

Query: 7    EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
            EF+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP DWQPPFA EV +FRFT
Sbjct: 12   EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFT 71

Query: 67   PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
            PRVQRLNELEA TRV+L++LDQ+AKFWE+QGS+LKIP VERKILDLY+LSKIV  +GG+E
Sbjct: 72   PRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFE 131

Query: 127  AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHPFDNEVK 186
             + K+++W++V  RL Y PGK  GSLL+SHYERI+YPYE+FQSG + +       D  +K
Sbjct: 132  MVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLD--LK 189

Query: 187  DK-EYKPHSIPLRQSVQP-SKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPK 244
            +K E +  S   + S +P ++ +   +R +R++   E    D+ ++ ELKKLQI+G GPK
Sbjct: 190  EKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPK 247

Query: 245  MMGLGLMAKDKDKTV--HKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQL 302
            ++GL +  KDK+  V   +KVT          +S   N+                  M+ 
Sbjct: 248  VVGLAMGTKDKEDEVTRRRKVT---------NRSDAFNMQ-----------------MRQ 281

Query: 303  RKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
            RK   S  F+D Y+C  C RG+ +DKLL CDGCDD+YH FCL+PPLP++P+G WRCPKC+
Sbjct: 282  RKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341

Query: 363  LAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSI 422
              EC +P EAFGFEQA +EY+LQSFGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVSSI
Sbjct: 342  AEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSI 401

Query: 423  EEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPP 482
            EEDV VEYGADI SK+FGSGFPV + ++ + PEE                          
Sbjct: 402  EEDVIVEYGADISSKDFGSGFPVKDGRRKILPEE-------------------------- 435

Query: 483  KVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSY 542
                 +EYA SGWNLN MPVL+QSVL HIN DISGMKVPWLYVGM FS+FCWHIEDHWSY
Sbjct: 436  -----EEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSY 490

Query: 543  SINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGV 602
            SINYLHWGEPKTWYGVPS AAE LEEVM+ L PELF+SQPDLLHQLVT+MNPN LM HGV
Sbjct: 491  SINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGV 550

Query: 603  PVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCV 662
            PV RTNQCAGEFV+TFPRAYHSGFNQGYNFAEAVNFCTADWLP GRQC+ HYRRLRR+CV
Sbjct: 551  PVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCV 610

Query: 663  FSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLP 722
            FSHEELI KMAA PE LD+ LA  V KE+ +M +EE RLR+++++ GV  +E E FEL+P
Sbjct: 611  FSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVP 670

Query: 723  DDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLH 782
            DDERQC  C+TTCFLSAL C   P+ LVCL H  DLC C   ++ LRYRY L++LP++L+
Sbjct: 671  DDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLY 730

Query: 783  KLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSE 842
             +K+RA+S+DTW ++V  AL      K+   ELR +  +A +R++P ++L ++L++ + E
Sbjct: 731  GVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKE 790

Query: 843  VEACIAQVLGLVSGQVARMDTP-------QLTLTELRVLLEQMGSLPCAMHQIGDVKDVL 895
             E C +    L+S +     +P       +LT+ EL+  ++Q+ SLPC + Q   VK++L
Sbjct: 791  AETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLL 850

Query: 896  EQVEAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA 955
            + VE +   A+EA+         L+ L++ G  L VE+PE  +L+Q+++QA+WLDEV+  
Sbjct: 851  DDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLT 910

Query: 956  LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKH 1015
            L+    + +L +M+ L+  G  +A   +V+KA AELQELLT++ERWEEKA  CL+AR +H
Sbjct: 911  LS-DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRH 969

Query: 1016 PPATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAV 1075
              A+LE+I+ E +NIP  LPN+ +LKEAL KA+ W A V+ IQ+G +Y  L+ LE L A 
Sbjct: 970  SVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAK 1029

Query: 1076 GRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADA---GSDSTK 1132
            GR +PV LE L Q+E QV  A +WRE+  +TFLKKNS +TLL+VL P  D    GS   +
Sbjct: 1030 GRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNR 1089

Query: 1133 RSRWMEKALGLYQCDTELLGLS-----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNS 1187
            R +  E      + D +L  LS      ++ RD   V+  FKE EQKE E +  LR  N 
Sbjct: 1090 RKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANL 1149

Query: 1188 AKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTS 1247
            AK +     +        C+C +  +G  +LQC+LC+DWFH  CV +P   +  K S   
Sbjct: 1150 AKMT----MVDRIEEVKFCICRKTASGF-MLQCELCKDWFHNSCVPLPKSSSQKKGS--- 1201

Query: 1248 SPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQ 1307
                +W   + KFLCPLCMRSRRPRLETIL+LLV+LQ+LPVRLPEGEALQCLTERA+ WQ
Sbjct: 1202 ----SWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQ 1257

Query: 1308 DRARKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSA 1348
            DRAR+ALA++++++ L +L+ L Q++  +   E+     SA
Sbjct: 1258 DRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISA 1298



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 4/106 (3%)

Query: 1393 SSLLPQ-LTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRT 1451
            S L+P+ L  PVLEL    +A LEELMM GDLLEV+LDE   IW++LQA  PP  DR   
Sbjct: 1423 SPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLH 1482

Query: 1452 LLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKR 1497
            ++E +  E +  + + +    ++R++K+++   VE L  +  Q  +
Sbjct: 1483 IMEDDSMEEKPLKVKGKDSSEKKRKRKLEK---VEQLFGEGKQKSK 1525


>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
            sapiens]
          Length = 1641

 Score = 1447 bits (3747), Expect = 0.0
 Identities = 735/1361 (54%), Positives = 948/1361 (69%), Gaps = 93/1361 (6%)

Query: 7    EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
            EF+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP DWQPPFA EV +FRFT
Sbjct: 12   EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFT 71

Query: 67   PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
            PRVQRLNELEA TRV+L++LDQ+AKFWE+QGS+LKIP VERKILDLY+LSKIV  +GG+E
Sbjct: 72   PRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFE 131

Query: 127  AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHPFDNEVK 186
             + K+++W++V  RL Y PGK  GSLL+SHYERI+YPYE+FQSG + +       D  +K
Sbjct: 132  MVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLD--LK 189

Query: 187  DK-EYKPHSIPLRQSVQP-SKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPK 244
            +K E +  S   + S +P ++ +   +R +R++   E    D+ ++ ELKKLQI+G GPK
Sbjct: 190  EKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPK 247

Query: 245  MMGLGLMAKDKDKTV--HKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQL 302
            ++GL +  KDK+  V   +KVT          +S   N+                  M+ 
Sbjct: 248  VVGLAMGTKDKEDEVTRRRKVT---------NRSDAFNMQ-----------------MRQ 281

Query: 303  RKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
            RK   S  F+D Y+C  C RG+ +DKLL CDGCDD+YH FCL+PPLP++P+G WRCPKC+
Sbjct: 282  RKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341

Query: 363  LAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSI 422
              EC +P EAFGFEQA +EY+LQSFGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVSSI
Sbjct: 342  AEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSI 401

Query: 423  EEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPP 482
            EEDV VEYGADI SK+FGSGFPV + ++ + PEE                          
Sbjct: 402  EEDVIVEYGADISSKDFGSGFPVKDGRRKILPEE-------------------------- 435

Query: 483  KVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSY 542
                 +EYA SGWNLN MPVL+QSVL HIN DISGMKVPWLYVGM FS+FCWHIEDHWSY
Sbjct: 436  -----EEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSY 490

Query: 543  SINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGV 602
            SINYLHWGEPKTWYGVPS AAE LEEVM+ L PELF+SQPDLLHQLVT+MNPN LM HGV
Sbjct: 491  SINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGV 550

Query: 603  PVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCV 662
            PV RTNQCAGEFV+TFPRAYHSGFNQGYNFAEAVNFCTADWLP GRQC+ HYRRLRR+CV
Sbjct: 551  PVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCV 610

Query: 663  FSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLP 722
            FSHEELI KMAA PE LD+ LA  V KE+ +M +EE RLR+++++ GV  +E E FEL+P
Sbjct: 611  FSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVP 670

Query: 723  DDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLH 782
            DDERQC  C+TTCFLSAL C   P+ LVCL H  DLC C   ++ LRYRY L++LP++L+
Sbjct: 671  DDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLY 730

Query: 783  KLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSE 842
             +K+RA+S+DTW ++V  AL      K+   ELR +  +A +R++P ++L ++L++ + E
Sbjct: 731  GVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKE 790

Query: 843  VEACIAQVLGLVSGQVARMDTP-------QLTLTELRVLLEQMGSLPCAMHQIGDVKDVL 895
             E C +    L+S +     +P       +LT+ EL+  ++Q+ SLPC + Q   VK++L
Sbjct: 791  AETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLL 850

Query: 896  EQVEAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA 955
            + VE +   A+EA+         L+ L++ G  L VE+PE  +L+Q+++QA+WLDEV+  
Sbjct: 851  DDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLT 910

Query: 956  LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKH 1015
            L+    + +L +M+ L+  G  +A   +V+KA AELQELLT++ERWEEKA  CL+AR +H
Sbjct: 911  LS-DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRH 969

Query: 1016 PPATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAV 1075
              A+LE+I+ E +NIP  LPN+ +LKEAL KA+ W A V+ IQ+G +Y  L+ LE L A 
Sbjct: 970  SVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAK 1029

Query: 1076 GRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADA---GSDSTK 1132
            GR +PV LE L Q+E QV  A +WRE+  +TFLKKNS +TLL+VL P  D    GS   +
Sbjct: 1030 GRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNR 1089

Query: 1133 RSRWMEKALGLYQCDTELLGLS-----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNS 1187
            R +  E      + D +L  LS      ++ RD   V+  FKE EQKE E +  LR  N 
Sbjct: 1090 RKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANL 1149

Query: 1188 AKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTS 1247
            AK +     +        C+C +  +G  +LQC+LC+DWFH  CV +P   +  K S   
Sbjct: 1150 AKMT----MVDRIEEVKFCICRKTASGF-MLQCELCKDWFHNSCVPLPKSSSQKKGS--- 1201

Query: 1248 SPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQ 1307
                +W   + KFLCPLCMRSRRPRLETIL+LLV+LQ+LPVRLPEGEALQCLTERA+ WQ
Sbjct: 1202 ----SWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQ 1257

Query: 1308 DRARKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSA 1348
            DRAR+ALA++++++ L +L+ L Q++  +   E+     SA
Sbjct: 1258 DRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISA 1298



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 4/106 (3%)

Query: 1393 SSLLPQ-LTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRT 1451
            S L+P+ L  PVLEL    +A LEELMM GDLLEV+LDE   IW++LQA  PP  DR   
Sbjct: 1428 SPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLH 1487

Query: 1452 LLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKR 1497
            ++E +  E +  + + +    ++R++K+++   VE L  +  Q  +
Sbjct: 1488 IMEDDSMEEKPLKVKGKDSSEKKRKRKLEK---VEQLFGEGKQKSK 1530


>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
          Length = 1544

 Score = 1303 bits (3371), Expect = 0.0
 Identities = 715/1581 (45%), Positives = 977/1581 (61%), Gaps = 146/1581 (9%)

Query: 7    EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
            EFLPPPECPVFEPSW EF DP  +I KIRPIAE++GICK+RPP DWQPPFA +VD   FT
Sbjct: 25   EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84

Query: 67   PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
            PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERKILDL+ L+K+V EEGG+ 
Sbjct: 85   PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144

Query: 127  AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP-FDNEV 185
             +CKDR+W ++A ++ + PGK +GS +R HYERI+ PY +F SG + ++C   P    + 
Sbjct: 145  VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSG-DSLRCLQKPNLTTDT 203

Query: 186  KDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKM 245
            KDKEYKPH IP RQSVQPS+    +RRAKR++ +    + + E+  E +           
Sbjct: 204  KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART---------- 253

Query: 246  MGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKN 305
                         + +++ CP      +++         + ++   +E   +      K 
Sbjct: 254  -----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKK 302

Query: 306  HSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAE 365
             ++A  +D Y+C +C  G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+  E
Sbjct: 303  ATNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360

Query: 366  CKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED 425
            C +P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEED
Sbjct: 361  CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420

Query: 426  VTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPPKVL 485
            VTVEYGADI SKEFGSGFPV + K  LSPEE                             
Sbjct: 421  VTVEYGADIASKEFGSGFPVRDGKIKLSPEE----------------------------- 451

Query: 486  GLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSIN 545
              +EY  SGWNLN MPV++QSVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSIN
Sbjct: 452  --EEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSIN 509

Query: 546  YLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVV 605
            YLHWGEPKTWYGVP  AAE LE VMK L PELF SQPDLLHQLVT+MNPNTLM+H VPV 
Sbjct: 510  YLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVY 569

Query: 606  RTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSH 665
            RTNQCAGEFVITFPRAYHSGFNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH
Sbjct: 570  RTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSH 629

Query: 666  EELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDDE 725
            +E+ICKMA+  + LD+ +A  V K+M IM+++E+ LR+ + + GV ++ER  FELLPDDE
Sbjct: 630  DEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDE 689

Query: 726  RQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLK 785
            RQC+KCKTTCF+SA++C   P  LVCL H+ +LC C   +  LRYRYTLD+L  M++ LK
Sbjct: 690  RQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALK 749

Query: 786  IRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSEVEA 845
            +RAES++ WA  V  ALE +  +K+S    +AL  E+  ++FP+++LL+ L+    + E 
Sbjct: 750  LRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEK 809

Query: 846  CIAQVLGLVSGQ-------VARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQV 898
            C +    L++G+              QLT+ ELR  + Q+ +LPC + Q   +KD+L +V
Sbjct: 810  CASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRV 869

Query: 899  EAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA-LA 957
            E +Q  +++ L+    S   L+ LL+   +  VE+P+  +++ ++EQA+WL+EV+QA L 
Sbjct: 870  EDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLD 929

Query: 958  PSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPP 1017
            PS+   +L  M+ L+ +G  +A   +V+KA A LQELLT++E W++KA   L+AR +H  
Sbjct: 930  PSSL--TLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSL 987

Query: 1018 ATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGR 1077
             +L   ++E E IP +LPN  ALK+++ +A+ W+ DV+ +Q G   P LD L  LV  GR
Sbjct: 988  NSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGR 1047

Query: 1078 DLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRS--R 1135
             +PV L  L +LE  V    +W+E A  TFL +NS Y+LLEVLCP  D G    KR   +
Sbjct: 1048 SIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRK 1107

Query: 1136 WMEKALGLYQCDTELLGLS-----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKP 1190
              E      +  T+L  LS       + ++  S +    E   +E E +  LR  N  K 
Sbjct: 1108 LKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGK- 1166

Query: 1191 SPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPL 1250
              L+P  +      IC+C + PA   ++QC+LC+D FH  CV+VP +         S  L
Sbjct: 1167 -LLSP--LQDVDIKICLCQKAPA-APMIQCELCRDAFHTSCVAVPSI---------SQGL 1213

Query: 1251 LAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRA 1310
              W       LCP C RS +P LE IL LL +LQR+ VRLPEG+AL+ + ER + WQ RA
Sbjct: 1214 RIW-------LCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRA 1266

Query: 1311 RKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQ---G 1367
            ++ L+S ++  +                                R GSG   S+ Q   G
Sbjct: 1267 QQLLSSGNLKFV------------------------------QDRVGSGLLYSRWQASAG 1296

Query: 1368 LLENGDSVTSPENMAPGKGS-----DLELLSSLL--PQLTGPVLELPEAIRAPLEELMME 1420
             + + + V+ P    PG  S     D +  +S L  P  TG        +   + EL+ME
Sbjct: 1297 QVSDTNKVSQP----PGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLME 1352

Query: 1421 GDLLEVTLDENHSIWQLLQAGQPPDLDRIRTLLELEKFEH----QGSRTRSRALERRRRR 1476
              LL+V+L E   ++Q L A   P     R+       E     +G R    +LER+ +R
Sbjct: 1353 AQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKR 1412

Query: 1477 QKVDQGRNVENLVQQELQSKRARSSGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLK 1536
            +   +G + E   ++  + +  +   I     ++  +++ + +R    +  +  HS  L 
Sbjct: 1413 RLEREGLSSERW-ERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHS--LP 1469

Query: 1537 GNQNSLQHKDS-GSSAACPSL 1556
             + +  + +DS    A CP++
Sbjct: 1470 SDTSYSEQEDSEDEDAICPAV 1490


>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
            domain 1B (RBP2-like), partial [Homo sapiens]
          Length = 977

 Score = 1104 bits (2855), Expect = 0.0
 Identities = 542/1008 (53%), Positives = 710/1008 (70%), Gaps = 66/1008 (6%)

Query: 7    EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
            EFLPPPECPVFEPSW EF DP  +I KIRPIAE++GICK+RPP DWQPPFA +VD   FT
Sbjct: 25   EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFT 84

Query: 67   PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
            PR+QRLNELEAQTRVKLN+LDQIAK+WE+QGS+LKIP+VERKILDL+ L+K+V EEGG+ 
Sbjct: 85   PRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFA 144

Query: 127  AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHP-FDNEV 185
             +CKDR+W ++A ++ + PGK +GS +R HYERI+ PY +F SG + ++C   P    + 
Sbjct: 145  VVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSG-DSLRCLQKPNLTTDT 203

Query: 186  KDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKM 245
            KDKEYKPH IP RQSVQPS+    +RRAKR++ +    + + E+  E +           
Sbjct: 204  KDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART---------- 253

Query: 246  MGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKN 305
                         + +++ CP      +++         + ++   +E   +      K 
Sbjct: 254  -----------HNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKK 302

Query: 306  HSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAE 365
             ++A  +D Y+C +C  G+++D+LL CDGCDD+YH FCL+PPL ++P+G WRCPKC+  E
Sbjct: 303  ATNA--VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 360

Query: 366  CKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEED 425
            C +P EAFGFEQA ++Y+L++FGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVS+IEED
Sbjct: 361  CSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEED 420

Query: 426  VTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPPKVL 485
            VTVEYGADI SKEFGSGFPV + K  LSPEE                             
Sbjct: 421  VTVEYGADIASKEFGSGFPVRDGKIKLSPEE----------------------------- 451

Query: 486  GLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSIN 545
              +EY  SGWNLN MPV++QSVL HI ADI GMK+PWLYVGM FS+FCWHIEDHWSYSIN
Sbjct: 452  --EEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSIN 509

Query: 546  YLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVV 605
            YLHWGEPKTWYGVP  AAE LE VMK L PELF SQPDLLHQLVT+MNPNTLM+H VPV 
Sbjct: 510  YLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVY 569

Query: 606  RTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSH 665
            RTNQCAGEFVITFPRAYHSGFNQG+NFAEAVNFCT DWLP GRQC+EHYR L RYCVFSH
Sbjct: 570  RTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSH 629

Query: 666  EELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDDE 725
            +E+ICKMA+  + LD+ +A  V K+M IM+++E+ LR+ + + GV ++ER  FELLPDDE
Sbjct: 630  DEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDE 689

Query: 726  RQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLK 785
            RQC+KCKTTCF+SA++C   P  LVCL H+ +LC C   +  LRYRYTLD+L  M++ LK
Sbjct: 690  RQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALK 749

Query: 786  IRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSEVEA 845
            +RAES++ WA  V  ALE +  +K+S    +AL  E+  ++FP+++LL+ L+    + E 
Sbjct: 750  LRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEK 809

Query: 846  CIAQVLGLVSGQ-------VARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQV 898
            C +    L++G+              QLT+ ELR  + Q+ +LPC + Q   +KD+L +V
Sbjct: 810  CASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRV 869

Query: 899  EAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA-LA 957
            E +Q  +++ L+    S   L+ LL+   +  VE+P+  +++ ++EQA+WL+EV+QA L 
Sbjct: 870  EDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLD 929

Query: 958  PSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKA 1005
            PS+   +L  M+ L+ +G  +A   +V+KA A LQELLT++E W++KA
Sbjct: 930  PSSL--TLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKA 975


>gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 506

 Score =  144 bits (362), Expect = 9e-34
 Identities = 94/296 (31%), Positives = 137/296 (46%), Gaps = 32/296 (10%)

Query: 419 VSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLP 478
           V+S +  V  +Y     +   G    ++NSK+  +P  +         L   +W      
Sbjct: 75  VTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHRN-----FADLEQRYWKSH--- 126

Query: 479 PWPPKVLG------LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAF 532
           P  P + G      L E +T  WNL  +  +   +       I G+  P+LY GM  + F
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 533 CWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLM 592
            WH ED   YSINYLH+GEPKTWY VP    +HLE + + L P++       L   V L+
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALI 246

Query: 593 NPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIE 652
           +P  L  +G+P     Q AGEF++TFP  YH+GFN G+N AEA+NF T  W+        
Sbjct: 247 SPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWI-------- 298

Query: 653 HYRRLRRYCVFSHEELICKMAAF-----PETLDL-----NLAVAVHKEMFIMVQEE 698
            Y ++   C      +   M  F     PE+ +L     +LA+  H E  +   +E
Sbjct: 299 DYGKMASQCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQE 354


>gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 506

 Score =  144 bits (362), Expect = 9e-34
 Identities = 94/296 (31%), Positives = 137/296 (46%), Gaps = 32/296 (10%)

Query: 419 VSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLP 478
           V+S +  V  +Y     +   G    ++NSK+  +P  +         L   +W      
Sbjct: 75  VTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHRN-----FADLEQRYWKSH--- 126

Query: 479 PWPPKVLG------LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAF 532
           P  P + G      L E +T  WNL  +  +   +       I G+  P+LY GM  + F
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 533 CWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLM 592
            WH ED   YSINYLH+GEPKTWY VP    +HLE + + L P++       L   V L+
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALI 246

Query: 593 NPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIE 652
           +P  L  +G+P     Q AGEF++TFP  YH+GFN G+N AEA+NF T  W+        
Sbjct: 247 SPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWI-------- 298

Query: 653 HYRRLRRYCVFSHEELICKMAAF-----PETLDL-----NLAVAVHKEMFIMVQEE 698
            Y ++   C      +   M  F     PE+ +L     +LA+  H E  +   +E
Sbjct: 299 DYGKMASQCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQE 354


>gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 506

 Score =  143 bits (361), Expect = 1e-33
 Identities = 94/296 (31%), Positives = 137/296 (46%), Gaps = 32/296 (10%)

Query: 419 VSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLP 478
           V+S +  V  +Y     +   G    ++NSK+  +P  +         L   +W      
Sbjct: 75  VTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHQN-----FADLEQRYWKSH--- 126

Query: 479 PWPPKVLG------LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAF 532
           P  P + G      L E +T  WNL  +  +   +       I G+  P+LY GM  + F
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 533 CWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLM 592
            WH ED   YSINYLH+GEPKTWY VP    +HLE + + L P++       L   V L+
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALI 246

Query: 593 NPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIE 652
           +P  L  +G+P     Q AGEF++TFP  YH+GFN G+N AEA+NF T  W+        
Sbjct: 247 SPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWI-------- 298

Query: 653 HYRRLRRYCVFSHEELICKMAAF-----PETLDL-----NLAVAVHKEMFIMVQEE 698
            Y ++   C      +   M  F     PE+ +L     +LA+  H E  +   +E
Sbjct: 299 DYGKMASQCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQE 354


>gi|39653317 jumonji domain containing 2D [Homo sapiens]
          Length = 523

 Score =  139 bits (351), Expect = 2e-32
 Identities = 101/322 (31%), Positives = 145/322 (45%), Gaps = 32/322 (9%)

Query: 395 KSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSP 454
           +  Y N+   ++ T L +      V+S    V  +Y     +   G    ++NSK+  +P
Sbjct: 60  RETYDNISEILIATPLQQ------VASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTP 113

Query: 455 EEKRQSLTVLTRLISSFWAQAVL--PPWPPKVLG-LQEYATSGWNLNVMPVLDQSVLCHI 511
               Q+   L R    +W   +   P +   + G L +  T  WNL  +  +   +    
Sbjct: 114 PH--QNFEDLER---KYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKEC 168

Query: 512 NADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMK 571
              I G+  P+LY GM  + F WH ED   YSINYLH GEPKTWY VP    + LE + +
Sbjct: 169 GVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLAR 228

Query: 572 MLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYN 631
            L P         L   V L++P  L  +G+P  R  Q AGEF++TFP  YH+GFN G+N
Sbjct: 229 ELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFN 288

Query: 632 FAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAF-----PETLDL----- 681
            AEA+NF T  W+         Y ++   C      +   M AF     PE  DL     
Sbjct: 289 CAEAINFATPRWI--------DYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 340

Query: 682 NLAVAVHKEMFIMVQEERRLRK 703
           + AV  H E  +   +E   +K
Sbjct: 341 DRAVVDHMEPRVPASQELSTQK 362


>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score =  138 bits (348), Expect = 4e-32
 Identities = 83/236 (35%), Positives = 116/236 (49%), Gaps = 14/236 (5%)

Query: 419 VSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLP 478
           V+S +  V  +Y     +   G    ++NSK+  +P  +         L   +W      
Sbjct: 75  VTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQN-----FADLEQRYWKSH--- 126

Query: 479 PWPPKVLG------LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAF 532
           P  P + G      L E +T  WNL  +  +   +       I G+  P+LY GM  + F
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 533 CWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLM 592
            WH ED   YSINYLH+GEPKTWY VP    + LE + + L P         L   V L+
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALI 246

Query: 593 NPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +P  L  +G+P  R  Q AGEF++TFP  YH+GFN G+N AEA+NF T  W+  G+
Sbjct: 247 SPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302


>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score =  138 bits (348), Expect = 4e-32
 Identities = 83/236 (35%), Positives = 116/236 (49%), Gaps = 14/236 (5%)

Query: 419 VSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLP 478
           V+S +  V  +Y     +   G    ++NSK+  +P  +         L   +W      
Sbjct: 75  VTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQN-----FADLEQRYWKSH--- 126

Query: 479 PWPPKVLG------LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAF 532
           P  P + G      L E +T  WNL  +  +   +       I G+  P+LY GM  + F
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 533 CWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLM 592
            WH ED   YSINYLH+GEPKTWY VP    + LE + + L P         L   V L+
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALI 246

Query: 593 NPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +P  L  +G+P  R  Q AGEF++TFP  YH+GFN G+N AEA+NF T  W+  G+
Sbjct: 247 SPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302


>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score =  138 bits (348), Expect = 4e-32
 Identities = 83/236 (35%), Positives = 116/236 (49%), Gaps = 14/236 (5%)

Query: 419 VSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLP 478
           V+S +  V  +Y     +   G    ++NSK+  +P  +         L   +W      
Sbjct: 75  VTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQN-----FADLEQRYWKSH--- 126

Query: 479 PWPPKVLG------LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAF 532
           P  P + G      L E +T  WNL  +  +   +       I G+  P+LY GM  + F
Sbjct: 127 PGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTF 186

Query: 533 CWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLM 592
            WH ED   YSINYLH+GEPKTWY VP    + LE + + L P         L   V L+
Sbjct: 187 AWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVALI 246

Query: 593 NPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +P  L  +G+P  R  Q AGEF++TFP  YH+GFN G+N AEA+NF T  W+  G+
Sbjct: 247 SPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGK 302


>gi|98986459 jumonji domain containing 2A [Homo sapiens]
          Length = 1064

 Score =  137 bits (345), Expect = 8e-32
 Identities = 68/165 (41%), Positives = 92/165 (55%)

Query: 487 LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINY 546
           L E     WN+  +  +   V       I G+  P+LY GM  ++F WH ED   YSINY
Sbjct: 140 LYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINY 199

Query: 547 LHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVR 606
           LH+GEPK+WY VP    + LE + K   P    S    L   +TL++P  L  +G+P  +
Sbjct: 200 LHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDK 259

Query: 607 TNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCI 651
             Q AGEF+ITFP  YH+GFN G+N AE+ NF T  W+  G+Q +
Sbjct: 260 VTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 2/65 (3%)

Query: 10 PPPECPVFEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
          P      F P+  EF++   YIA I    A ++G+ K+ PP +W+P  +  ++D+     
Sbjct: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69

Query: 68 RVQRL 72
           +Q+L
Sbjct: 70 PIQQL 74


>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
          Length = 813

 Score =  131 bits (330), Expect = 4e-30
 Identities = 62/154 (40%), Positives = 87/154 (56%)

Query: 495 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 554
           WN+  +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+
Sbjct: 150 WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKS 209

Query: 555 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 614
           WY +P    + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF
Sbjct: 210 WYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEF 269

Query: 615 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 270 MITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71

Query: 68 RVQRL 72
           +Q++
Sbjct: 72 PIQQM 76


>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
          Length = 835

 Score =  131 bits (330), Expect = 4e-30
 Identities = 62/154 (40%), Positives = 87/154 (56%)

Query: 495 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 554
           WN+  +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+
Sbjct: 172 WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKS 231

Query: 555 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 614
           WY +P    + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF
Sbjct: 232 WYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEF 291

Query: 615 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 292 MITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 325



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 34 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 93

Query: 68 RVQRL 72
           +Q++
Sbjct: 94 PIQQM 98


>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
          Length = 1047

 Score =  131 bits (330), Expect = 4e-30
 Identities = 62/154 (40%), Positives = 87/154 (56%)

Query: 495 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 554
           WN+  +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+
Sbjct: 150 WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKS 209

Query: 555 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 614
           WY +P    + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF
Sbjct: 210 WYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEF 269

Query: 615 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 270 MITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71

Query: 68 RVQRL 72
           +Q++
Sbjct: 72 PIQQM 76


>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
          Length = 1056

 Score =  131 bits (330), Expect = 4e-30
 Identities = 62/154 (40%), Positives = 87/154 (56%)

Query: 495 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 554
           WN+  +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+
Sbjct: 150 WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKS 209

Query: 555 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 614
           WY +P    + LE + +   P         L   +TL++P+ L  +G+P  +  Q AGEF
Sbjct: 210 WYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEF 269

Query: 615 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 270 MITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
          P C +  F PS  EF++   Y+A +    A ++G+ K+ PP +W+P     ++DN     
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPA 71

Query: 68 RVQRL 72
           +Q++
Sbjct: 72 PIQQM 76


>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
            sapiens]
          Length = 1246

 Score =  131 bits (330), Expect = 4e-30
 Identities = 110/428 (25%), Positives = 183/428 (42%), Gaps = 78/428 (18%)

Query: 383  SLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSG 442
            SL +F   A +  S  F+      P E +E+E+WRLV   +  V V  G  + +   GSG
Sbjct: 821  SLTTFYRTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSG 876

Query: 443  FPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPPKVLGLQEYATSGWNLNVMPV 502
            FPV  S                                       + ++  GWNL V+P 
Sbjct: 877  FPVGKS---------------------------------------EPFSRHGWNLTVLPN 897

Query: 503  LDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA 562
               S+L H+ A + G+ +PWL +GMVFS  CW  + +    I+YLH G    WY +P+  
Sbjct: 898  NTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEE 956

Query: 563  AEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY 622
               LE+V+  L          +L   V +++P  L   G+ V RT Q +G+FV+ FP ++
Sbjct: 957  ENKLEDVVHTLLQANGTPGLQMLESNV-MISPEVLCKEGIKVHRTVQQSGQFVVCFPGSF 1015

Query: 623  HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLN 682
             S    GY+ +E V+F T  W   G +  +  +R      FS E+L+ ++A      +  
Sbjct: 1016 VSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENG 1075

Query: 683  LAVAVHKEMFIMVQE-ERRLRKALLEKGVTEAER-----------------EAFELLPDD 724
              ++    +   +++ E R R+ L E G+  + R                   +  L   
Sbjct: 1076 PTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETS 1135

Query: 725  ERQCIKCKTTCFLSALA--------CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDE 776
            ER+C  C+  C+LS +         C +C      L H+     C   +  L YRY  ++
Sbjct: 1136 ERRCQICQHLCYLSMVVQENENVVFCLEC-----ALRHVEKQKSCRGLK--LMYRYDEEQ 1188

Query: 777  LPTMLHKL 784
            + ++++++
Sbjct: 1189 IISLVNQI 1196



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 2/133 (1%)

Query: 13  ECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRVQRL 72
           E PV  PS  EF DPL YI  +R   EK G+C++ PP DW+P   +  D  RF  ++Q +
Sbjct: 556 EIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLN-DEMRFVTQIQHI 614

Query: 73  NELEAQTRVKLNYLDQIAKFWEIQGSSL-KIPNVERKILDLYSLSKIVIEEGGYEAICKD 131
           ++L  +    +  L  I K  + QG ++ ++P +    LDL    +++ E GG + +   
Sbjct: 615 HKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDL 674

Query: 132 RRWARVAQRLHYP 144
           ++W ++A  L  P
Sbjct: 675 KKWNKLADMLRIP 687


>gi|45504380 jumonji domain containing 2B [Homo sapiens]
          Length = 1096

 Score =  130 bits (326), Expect = 1e-29
 Identities = 63/154 (40%), Positives = 85/154 (55%)

Query: 495 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 554
           WN+  +  +   V       I G+  P+LY GM  + F WH ED   YSINYLH+GEPK+
Sbjct: 149 WNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKS 208

Query: 555 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 614
           WY +P    + LE +     P         L   +TL++P  L  +G+P  R  Q AGEF
Sbjct: 209 WYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEF 268

Query: 615 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 648
           +ITFP  YH+GFN G+N AE+ NF T  W+  G+
Sbjct: 269 MITFPYGYHAGFNHGFNCAESTNFATLRWIDYGK 302



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 3/46 (6%)

Query: 12 PECPV--FEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQP 54
          P C +  F P+  EF+D   Y+A I    A ++G+ KI PP +W+P
Sbjct: 11 PSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKP 56


>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
          Length = 1648

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 27/49 (55%), Positives = 33/49 (67%)

Query: 313 DSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKC 361
           D   C+VC R D +D+LL CDGCD  YH+ CL PPL E+P   W CP+C
Sbjct: 182 DPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPEC 230


>gi|205830434 D4, zinc and double PHD fingers family 1 isoform c
           [Homo sapiens]
          Length = 332

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 25/53 (47%), Positives = 33/53 (62%)

Query: 310 QFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
           Q I+   C +C   + DD+LLFCD CD  YH++CL PP+ E P G W C  C+
Sbjct: 266 QCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 318


>gi|205830430 D4, zinc and double PHD fingers family 1 isoform a
           [Homo sapiens]
          Length = 414

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 25/53 (47%), Positives = 33/53 (62%)

Query: 310 QFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
           Q I+   C +C   + DD+LLFCD CD  YH++CL PP+ E P G W C  C+
Sbjct: 348 QCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 400


>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
            sapiens]
          Length = 1483

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 7/81 (8%)

Query: 317  CQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQPPEAFGFE 376
            C+VC +  EDDKL+ CD C+  +H+FCL P L E+P G W+CP C  A  ++        
Sbjct: 1187 CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARR-------N 1239

Query: 377  QATQEYSLQSFGEMADSFKSD 397
               + Y+ +S  E ++  +SD
Sbjct: 1240 SRGRNYTEESASEDSEDDESD 1260


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
            sapiens]
          Length = 2168

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 31/92 (33%), Positives = 47/92 (51%)

Query: 271  VKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLL 330
            ++++ + G  V    L +  S         QL+K+ +  + I    CQ+C +GD ++ LL
Sbjct: 1888 IEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLL 1947

Query: 331  FCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
             CDGCD   H +C  P +  IP G W CP CI
Sbjct: 1948 LCDGCDKGCHTYCHRPKITTIPDGDWFCPACI 1979


>gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]
          Length = 391

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 24/53 (45%), Positives = 32/53 (60%)

Query: 310 QFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
           Q I+   C +C   + DD+LLFCD CD  YH++CL P + E P G W C  C+
Sbjct: 323 QCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 26/67 (38%), Positives = 36/67 (53%), Gaps = 1/67 (1%)

Query: 295 CTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRG 354
           C  T +  RK  +  Q  +  +CQ C +   D K+L C+ CD  YH FCL PP+ E+P  
Sbjct: 255 CLDTALTARKR-AGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAH 313

Query: 355 IWRCPKC 361
            W+C  C
Sbjct: 314 SWKCKAC 320



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 21/51 (41%), Positives = 34/51 (66%)

Query: 312  IDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
            ++  +C+VC +  +  +LL CD CD +YH +CL PPL  +P+G W+C  C+
Sbjct: 1425 VECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCV 1475



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 2/75 (2%)

Query: 297 KTTMQLRKNHSS-AQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGI 355
           KT   L   HS  A +++   C VC    E   L FC  C  +YH  CL   L    R  
Sbjct: 208 KTLQLLCPEHSEGAAYLEEARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAG 267

Query: 356 WRCPKC-ILAECKQP 369
           W+CP+C +   C++P
Sbjct: 268 WQCPECKVCQACRKP 282



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 7/55 (12%)

Query: 316  ICQVCS---RGDEDDKLLFCDGCDDNYHIFCLLPPLPEIP--RGIWRCPKCILAE 365
            +C VC    RG E   LL C  C   YH +C+   + ++   +G WRC +CI+ E
Sbjct: 1379 MCVVCGSFGRGAEGH-LLACSQCSQCYHPYCVNSKITKVMLLKG-WRCVECIVCE 1431


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,029,016
Number of Sequences: 37866
Number of extensions: 3258711
Number of successful extensions: 10899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 10123
Number of HSP's gapped (non-prelim): 886
length of query: 1570
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1454
effective length of database: 13,855,062
effective search space: 20145260148
effective search space used: 20145260148
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.