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Search of human proteins with 226371623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226371623 transcription factor 7-like 2 isoform 4 [Homo
sapiens]
(455 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 946 0.0
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 892 0.0
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 890 0.0
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 870 0.0
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 854 0.0
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 840 0.0
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 586 e-167
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 456 e-128
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 407 e-113
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 398 e-111
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is... 297 1e-80
gi|42518078 transcription factor 7 (T-cell specific, HMG-box) is... 243 2e-64
gi|47419938 transcription factor 7 (T-cell specific, HMG-box) is... 243 2e-64
gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6... 234 9e-62
gi|42518074 transcription factor 7 (T-cell specific, HMG-box) is... 234 2e-61
gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5... 233 4e-61
gi|42714657 transcription factor 7 (T-cell specific, HMG-box) is... 233 4e-61
gi|112421108 capicua homolog [Homo sapiens] 74 4e-13
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 70 3e-12
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 70 3e-12
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 66 7e-11
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 66 7e-11
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 66 7e-11
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 66 7e-11
gi|41406089 SRY-box 13 [Homo sapiens] 65 2e-10
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 61 2e-09
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 61 2e-09
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 61 2e-09
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 59 9e-09
gi|4759162 SRY-box 14 [Homo sapiens] 59 1e-08
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 946 bits (2446), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
Sbjct: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
Query: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
Sbjct: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
Query: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
Sbjct: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
Query: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQP 240
ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQP
Sbjct: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQP 240
Query: 241 VYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSD 300
VYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSD
Sbjct: 241 VYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSD 300
Query: 301 VGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRR 360
VGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRR
Sbjct: 301 VGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRR 360
Query: 361 WHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLN 420
WHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLN
Sbjct: 361 WHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLN 420
Query: 421 PCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY 455
PCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
Sbjct: 421 PCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY 455
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 892 bits (2305), Expect = 0.0
Identities = 438/459 (95%), Positives = 438/459 (95%), Gaps = 21/459 (4%)
Query: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
Sbjct: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
Query: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
Sbjct: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
Query: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
Sbjct: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
Query: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW---- 236
ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
Sbjct: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ 240
Query: 237 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES 296
QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
Sbjct: 241 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES 300
Query: 297 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 356
SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
Sbjct: 301 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 360
Query: 357 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE 416
LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
Sbjct: 361 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN---- 416
Query: 417 CFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY 455
GEKKSAFATYKVKAAASAHPLQMEAY
Sbjct: 417 -------------GEKKSAFATYKVKAAASAHPLQMEAY 442
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 890 bits (2301), Expect = 0.0
Identities = 429/433 (99%), Positives = 429/433 (99%), Gaps = 4/433 (0%)
Query: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
Sbjct: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
Query: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
Sbjct: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
Query: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
Sbjct: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
Query: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW---- 236
ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
Sbjct: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ 240
Query: 237 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES 296
QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
Sbjct: 241 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES 300
Query: 297 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 356
SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
Sbjct: 301 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 360
Query: 357 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE 416
LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
Sbjct: 361 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE 420
Query: 417 CFLNPCLSLPPIT 429
CFLNPCLSLPPIT
Sbjct: 421 CFLNPCLSLPPIT 433
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 870 bits (2247), Expect = 0.0
Identities = 438/506 (86%), Positives = 438/506 (86%), Gaps = 68/506 (13%)
Query: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
Sbjct: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
Query: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
Sbjct: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
Query: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIV------------------- 161
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIV
Sbjct: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSPLPCCTQGHDCQHFYPPS 180
Query: 162 ----------------------------SNKVPVVQHPHHVHPLTPLITYSNEHFTPGNP 193
SNKVPVVQHPHHVHPLTPLITYSNEHFTPGNP
Sbjct: 181 DFTVSTQVFRDMKRSHSLQKVGEPWCIESNKVPVVQHPHHVHPLTPLITYSNEHFTPGNP 240
Query: 194 PPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----QGQPVYPITTGGF 249
PPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW QGQPVYPITTGGF
Sbjct: 241 PPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGF 300
Query: 250 RHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKH 309
RHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKH
Sbjct: 301 RHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKH 360
Query: 310 QDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQ 369
QDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQ
Sbjct: 361 QDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQ 420
Query: 370 AKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPIT 429
AKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
Sbjct: 421 AKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN----------------- 463
Query: 430 GEKKSAFATYKVKAAASAHPLQMEAY 455
GEKKSAFATYKVKAAASAHPLQMEAY
Sbjct: 464 GEKKSAFATYKVKAAASAHPLQMEAY 489
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 854 bits (2206), Expect = 0.0
Identities = 413/419 (98%), Positives = 414/419 (98%), Gaps = 4/419 (0%)
Query: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
Sbjct: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
Query: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
Sbjct: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
Query: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
Sbjct: 121 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL 180
Query: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW---- 236
ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
Sbjct: 181 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ 240
Query: 237 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES 296
QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
Sbjct: 241 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES 300
Query: 297 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 356
SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
Sbjct: 301 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 360
Query: 357 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHS 415
LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN+ S
Sbjct: 361 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNDLS 419
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 840 bits (2171), Expect = 0.0
Identities = 412/440 (93%), Positives = 413/440 (93%), Gaps = 27/440 (6%)
Query: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
Sbjct: 1 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS 60
Query: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
Sbjct: 61 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS 120
Query: 121 LSPTART-----------------------YLQMKWPLLDVQAGSLQSRQALKDARSPSP 157
LSPTART YLQMKWPLLDVQAGSLQSRQALKDARSPSP
Sbjct: 121 LSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSP 180
Query: 158 AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS 217
AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS
Sbjct: 181 AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS 240
Query: 218 PYYPLSPGTVGQIPHPLGW----QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP 273
PYYPLSPGTVGQIPHPLGW QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP
Sbjct: 241 PYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP 300
Query: 274 HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY 333
HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY
Sbjct: 301 HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY 360
Query: 334 MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR 393
MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
Sbjct: 361 MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR 420
Query: 394 DNYGKKKKRKRDKQPGETNE 413
DNYGKKKKRKRDKQPGETN+
Sbjct: 421 DNYGKKKKRKRDKQPGETND 440
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 586 bits (1511), Expect = e-167
Identities = 298/422 (70%), Positives = 341/422 (80%), Gaps = 21/422 (4%)
Query: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
Query: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPT- 124
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
Query: 125 ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYS 184
ARTYLQMKWPLLDV + + +KD RSPSPAH+ SNKVPVVQHPHH+HPLTPLITYS
Sbjct: 145 ARTYLQMKWPLLDVPSSA-----TVKDTRSPSPAHL-SNKVPVVQHPHHMHPLTPLITYS 198
Query: 185 NEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----QGQP 240
N+HF+PG+PP HL ++DPKTGIPRPPHP ++SPYYPLSPG VGQIPHPLGW QGQP
Sbjct: 199 NDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQP 258
Query: 241 VYPITTGGFRHPYPTALTVNASMS-----RFPPHMVPPHHT-LHTTGIPHPAIVTPTVKQ 294
+Y + GGFRHPYP AL +NASMS RF PHMV P H L T+GIPHPAIV+P VKQ
Sbjct: 259 MYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQ 317
Query: 295 ESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 354
E + + S K + K+EE+KKPH+KKPLNAFMLYMKEMRAKVVAECTLKESAAIN
Sbjct: 318 EPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 377
Query: 355 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEH 414
QILGR+WH LSREEQAKYYELARKERQLH QLYP WSARDNYGKKKKRKR+KQ +T
Sbjct: 378 QILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQ 437
Query: 415 SE 416
+
Sbjct: 438 QQ 439
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 456 bits (1174), Expect = e-128
Identities = 249/418 (59%), Positives = 290/418 (69%), Gaps = 48/418 (11%)
Query: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
Query: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
QI PLGWQGQPVYPIT GGFR PYP++L+V+ SMSRF HM+P HTTGIPHPAIV
Sbjct: 206 QITPPLGWQGQPVYPIT-GGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIV 264
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
TP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLK
Sbjct: 265 TPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLK 324
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDK 406
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 325 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREK 382
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 407 bits (1046), Expect = e-113
Identities = 240/466 (51%), Positives = 281/466 (60%), Gaps = 93/466 (19%)
Query: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
Query: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
QI PLGW F HM+P HTTGIPHPAIV
Sbjct: 206 QITPPLGW-----------------------------FSHHMIPGPPGPHTTGIPHPAIV 236
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
TP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLK
Sbjct: 237 TPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLK 296
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 297 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQ 356
Query: 409 GETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEA 454
+G K+S+F T K KAA L+MEA
Sbjct: 357 ESA-----------------SGGKRSSFPTCKAKAATPGPLLEMEA 385
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 398 bits (1022), Expect = e-111
Identities = 227/418 (54%), Positives = 264/418 (63%), Gaps = 76/418 (18%)
Query: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
Query: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
QI PLGW F HM+P HTTGIPHPAIV
Sbjct: 206 QITPPLGW-----------------------------FSHHMIPGPPGPHTTGIPHPAIV 236
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
TP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLK
Sbjct: 237 TPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLK 296
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDK 406
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 297 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREK 354
>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
Length = 384
Score = 297 bits (761), Expect = 1e-80
Identities = 203/474 (42%), Positives = 249/474 (52%), Gaps = 115/474 (24%)
Query: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSA--ERDLADVKSSLVNESE 53
MPQL+ GGG DDLGA DEL++F+DEGE+++ S +S+A ERDLA++KSSLVNESE
Sbjct: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
Query: 54 -------------TNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQD--GGLFKGP 98
+ ++EA R F DK E LE+ K + G++K
Sbjct: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
Query: 99 PYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPA 158
Y + +M Y P +G+ Q Q P P
Sbjct: 121 VYSAFNLLM------HYPP---------------------PSGAGQHPQ-------PQPP 146
Query: 159 HIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISP 218
+N+ P H + L Y EHF +P P PAD+ K + RP PD+S
Sbjct: 147 LHKANQPP--------HGVPQLSLY--EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSG 194
Query: 219 YYPLSPGTVGQIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLH 278
+Y L+ G++GQ+PH + W P + +G HP
Sbjct: 195 FYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHP-------------------------- 228
Query: 279 TTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMR 338
IPHPAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMR
Sbjct: 229 -AAIPHPAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMR 284
Query: 339 AKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGK 398
AKV+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGK
Sbjct: 285 AKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGK 344
Query: 399 KKKRKRDKQPGETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQM 452
KK+R R+K T TG K++AF TY KAAA A L M
Sbjct: 345 KKRRSREKHQEST-----------------TGGKRNAFGTYPEKAAAPAPFLPM 381
>gi|42518078 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 243 bits (621), Expect = 2e-64
Identities = 145/284 (51%), Positives = 167/284 (58%), Gaps = 54/284 (19%)
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Q+PH + W P + +G HP IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
Query: 409 GETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQM 452
T TG K++AF TY KAAA A L M
Sbjct: 240 EST-----------------TGGKRNAFGTYPEKAAAPAPFLPM 266
>gi|47419938 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 243 bits (621), Expect = 2e-64
Identities = 145/284 (51%), Positives = 167/284 (58%), Gaps = 54/284 (19%)
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Q+PH + W P + +G HP IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
Query: 409 GETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQM 452
T TG K++AF TY KAAA A L M
Sbjct: 240 EST-----------------TGGKRNAFGTYPEKAAAPAPFLPM 266
>gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6
[Homo sapiens]
Length = 250
Score = 234 bits (598), Expect = 9e-62
Identities = 132/247 (53%), Positives = 154/247 (62%), Gaps = 37/247 (14%)
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Q+PH + W P + +G HP IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
Query: 409 GETNEHS 415
T ++S
Sbjct: 240 ESTTDNS 246
>gi|42518074 transcription factor 7 (T-cell specific, HMG-box)
isoform 3 [Homo sapiens]
Length = 269
Score = 234 bits (596), Expect = 2e-61
Identities = 132/245 (53%), Positives = 152/245 (62%), Gaps = 37/245 (15%)
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Q+PH + W P + +G HP IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
Query: 409 GETNE 413
T E
Sbjct: 240 ESTTE 244
>gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5
[Homo sapiens]
Length = 366
Score = 233 bits (593), Expect = 4e-61
Identities = 131/245 (53%), Positives = 152/245 (62%), Gaps = 37/245 (15%)
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Q+PH + W P + +G HP IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
Query: 409 GETNE 413
T +
Sbjct: 240 ESTTD 244
>gi|42714657 transcription factor 7 (T-cell specific, HMG-box)
isoform 4 [Homo sapiens]
Length = 268
Score = 233 bits (593), Expect = 4e-61
Identities = 131/245 (53%), Positives = 152/245 (62%), Gaps = 37/245 (15%)
Query: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Q+PH + W P + +G HP IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Query: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
Query: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
Query: 409 GETNE 413
T +
Sbjct: 240 ESTTD 244
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 73.6 bits (179), Expect = 4e-13
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 21/193 (10%)
Query: 205 TGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMS 264
TG P PP + P SPG PHPLG + G + P PT AS
Sbjct: 89 TGSADPERPPGAT--CPESPGPGP--PHPLG--------VVESG-KGPPPTT-EEEASGP 134
Query: 265 RFPPHMVPPHHTLHTTG---IPHPAIVTPTVKQESSQSDVGSL----HSSKHQDSKKEEE 317
P + + H I P I P + + +L SS +D + +
Sbjct: 135 PGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNK 194
Query: 318 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 377
++K HI++P+NAFM++ K RA V +++ +++ILG W+AL +E+ KY++LA
Sbjct: 195 REKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAF 254
Query: 378 KERQLHMQLYPGW 390
+ ++ H + +P W
Sbjct: 255 QVKEAHFKAHPDW 267
Score = 35.4 bits (80), Expect = 0.11
Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 17/115 (14%)
Query: 222 LSPGTVG-------QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMV--- 271
L+PG VG Q+P G PV G P PT+ A S+ PP +V
Sbjct: 1065 LAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSG--SPAPTSSAPLAQPSQAPPSLVYTV 1122
Query: 272 -----PPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKP 321
PP T+ G P PA TP + GS+ S + K P
Sbjct: 1123 ATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAP 1177
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 70.5 bits (171), Expect = 3e-12
Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 13/169 (7%)
Query: 246 TGGFRHPYPTALTVNASMSRFPPHM------VPPHHTLHTTGIPHPAIVT-------PTV 292
T G P+ L + ++ PP PP + T +P + T P+V
Sbjct: 247 TSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQSLLEPSV 306
Query: 293 KQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAA 352
K E+ + L S + + H+K+P+NAFM++ + R + +A
Sbjct: 307 KIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAE 366
Query: 353 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK 401
I+ LG W+ LS E++ YY+ A+K ++ H + +PGW + GK+K+
Sbjct: 367 ISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKR 415
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 70.5 bits (171), Expect = 3e-12
Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 13/169 (7%)
Query: 246 TGGFRHPYPTALTVNASMSRFPPHM------VPPHHTLHTTGIPHPAIVT-------PTV 292
T G P+ L + ++ PP PP + T +P + T P+V
Sbjct: 247 TSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQSLLEPSV 306
Query: 293 KQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAA 352
K E+ + L S + + H+K+P+NAFM++ + R + +A
Sbjct: 307 KIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAE 366
Query: 353 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK 401
I+ LG W+ LS E++ YY+ A+K ++ H + +PGW + GK+K+
Sbjct: 367 ISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKR 415
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 65.9 bits (159), Expect = 7e-11
Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)
Query: 320 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 379
+PHIK+P+NAFM++ K+ R K++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 631 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 690
Query: 380 RQLHMQLYPGWSARDNYGKKKKRKR 404
++H++ YP NY K + KR
Sbjct: 691 SKIHLEKYP------NYKYKPRPKR 709
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 65.9 bits (159), Expect = 7e-11
Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)
Query: 320 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 379
+PHIK+P+NAFM++ K+ R K++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 591 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 650
Query: 380 RQLHMQLYPGWSARDNYGKKKKRKR 404
++H++ YP NY K + KR
Sbjct: 651 SKIHLEKYP------NYKYKPRPKR 669
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 65.9 bits (159), Expect = 7e-11
Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)
Query: 320 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 379
+PHIK+P+NAFM++ K+ R K++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 594 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 653
Query: 380 RQLHMQLYPGWSARDNYGKKKKRKR 404
++H++ YP NY K + KR
Sbjct: 654 SKIHLEKYP------NYKYKPRPKR 672
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 65.9 bits (159), Expect = 7e-11
Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 6/85 (7%)
Query: 320 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKE 379
+PHIK+P+NAFM++ K+ R K++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 598 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 657
Query: 380 RQLHMQLYPGWSARDNYGKKKKRKR 404
++H++ YP NY K + KR
Sbjct: 658 SKIHLEKYP------NYKYKPRPKR 676
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 64.7 bits (156), Expect = 2e-10
Identities = 68/296 (22%), Positives = 115/296 (38%), Gaps = 67/296 (22%)
Query: 160 IVSNKVPVVQHPHHVHPLTPLITYSNEHFT--PGNPPPHLPADVDPKTGIPRPPHPPDIS 217
I + ++Q H ++ L I N + P PP H P V P + + P P
Sbjct: 198 IAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCK 257
Query: 218 PY-YPLS-----PGTVGQIP------HPLGWQGQPVYPITTGGFRHPYPTALTVNASMSR 265
P YPL P V + P HPL QP+ T+ + + MS
Sbjct: 258 PVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSS 317
Query: 266 FPPHMVPPHHTLHTTGIPH--PAI----------VTPTVK--QESSQSDVGSLHSSKHQD 311
P PP H T + P++ VT ++ ++ S G+L S +
Sbjct: 318 CVPR--PPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALDGSPNTP 375
Query: 312 SKKE-------------------------------------EEKKKPHIKKPLNAFMLYM 334
+K+ E + HIK+P+NAFM++
Sbjct: 376 FRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWA 435
Query: 335 KEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 390
K+ R K++ +++I++ILG RW +++ +E+ YYE + + H++ YP +
Sbjct: 436 KDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDY 491
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 60.8 bits (146), Expect = 2e-09
Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Query: 297 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 356
S G S +++S+ + PHIK+P+NAFM++ K+ R K++ ++ I++I
Sbjct: 145 SDGSAGVSESRIYRESRGRGSNE-PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 203
Query: 357 LGRRWHALSREEQAKYYELARKERQLHMQLYPGW 390
LG RW A++ E+ YYE + + H++ YP +
Sbjct: 204 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDY 237
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 60.8 bits (146), Expect = 2e-09
Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Query: 297 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 356
S G S +++S+ + PHIK+P+NAFM++ K+ R K++ ++ I++I
Sbjct: 518 SDGSAGVSESRIYRESRGRGSNE-PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 576
Query: 357 LGRRWHALSREEQAKYYELARKERQLHMQLYPGW 390
LG RW A++ E+ YYE + + H++ YP +
Sbjct: 577 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDY 610
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 60.8 bits (146), Expect = 2e-09
Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Query: 297 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 356
S G S +++S+ + PHIK+P+NAFM++ K+ R K++ ++ I++I
Sbjct: 531 SDGSAGVSESRIYRESRGRGSNE-PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 589
Query: 357 LGRRWHALSREEQAKYYELARKERQLHMQLYPGW 390
LG RW A++ E+ YYE + + H++ YP +
Sbjct: 590 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDY 623
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 58.9 bits (141), Expect = 9e-09
Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 6/104 (5%)
Query: 318 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 377
K KPH+K+P+NAFM++ + R K+ + +A +++ LG+ W LS E+ + E A
Sbjct: 97 KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156
Query: 378 KERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNP 421
+ R H + +P +Y + +R++ + G ++ S L P
Sbjct: 157 RLRVQHKKDHP------DYKYQPRRRKSAKAGHSDSDSGAELGP 194
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/89 (32%), Positives = 48/89 (53%)
Query: 318 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 377
K HIK+P+NAFM++ + R K+ E ++ I++ LG W LS E+ Y + A+
Sbjct: 3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAK 62
Query: 378 KERQLHMQLYPGWSARDNYGKKKKRKRDK 406
+ R HM+ +P + R K K+D+
Sbjct: 63 RLRAQHMKEHPDYKYRPRRKPKNLLKKDR 91
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,616,794
Number of Sequences: 37866
Number of extensions: 1349655
Number of successful extensions: 8854
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 6886
Number of HSP's gapped (non-prelim): 1973
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.