BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sapiens] (1083 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sa... 2132 0.0 gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap... 2046 0.0 gi|116284392 mucin 2 precursor [Homo sapiens] 127 4e-29 gi|91982772 mucin 17 [Homo sapiens] 124 6e-28 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 107 6e-23 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 107 6e-23 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 107 6e-23 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 107 6e-23 gi|83367077 mucin 16 [Homo sapiens] 102 3e-21 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 100 7e-21 gi|167736355 mucin 4 isoform a [Homo sapiens] 100 1e-20 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 1e-20 gi|151301154 mucin 6, gastric [Homo sapiens] 99 2e-20 gi|163965366 nascent polypeptide-associated complex alpha subuni... 97 6e-20 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 93 1e-18 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 91 5e-18 gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 84 7e-16 gi|161019170 mucin 5AC [Homo sapiens] 84 9e-16 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 83 2e-15 gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 82 4e-15 gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 80 8e-15 gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 80 1e-14 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 76 2e-13 gi|148612879 polyhomeotic like 3 [Homo sapiens] 75 3e-13 gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 73 1e-12 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 73 1e-12 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 73 1e-12 gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 71 5e-12 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 71 6e-12 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 70 1e-11 >gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sapiens] Length = 1083 Score = 2132 bits (5524), Expect = 0.0 Identities = 1083/1083 (100%), Positives = 1083/1083 (100%) Query: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP Sbjct: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 Query: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA Sbjct: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 Query: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI Sbjct: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 Query: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM Sbjct: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS Sbjct: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL Sbjct: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA Sbjct: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS Sbjct: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV Sbjct: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ Sbjct: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 Query: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP Sbjct: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 Query: 661 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE 720 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE Sbjct: 661 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE 720 Query: 721 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 780 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP Sbjct: 721 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 780 Query: 781 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 840 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT Sbjct: 781 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 840 Query: 841 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS 900 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS Sbjct: 841 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS 900 Query: 901 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE 960 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE Sbjct: 901 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE 960 Query: 961 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD 1020 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD Sbjct: 961 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD 1020 Query: 1021 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK 1080 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK Sbjct: 1021 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK 1080 Query: 1081 EKV 1083 EKV Sbjct: 1081 EKV 1083 >gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sapiens] Length = 1048 Score = 2046 bits (5300), Expect = 0.0 Identities = 1048/1083 (96%), Positives = 1048/1083 (96%), Gaps = 35/1083 (3%) Query: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP Sbjct: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 Query: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA Sbjct: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 Query: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI Sbjct: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 Query: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM Sbjct: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS Sbjct: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL Sbjct: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA Sbjct: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS Sbjct: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV Sbjct: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ Sbjct: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 Query: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP Sbjct: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 Query: 661 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE 720 AQGSSPRPSILRKKPATD GAKPKSE Sbjct: 661 AQGSSPRPSILRKKPATD-----------------------------------GAKPKSE 685 Query: 721 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 780 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP Sbjct: 686 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 745 Query: 781 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 840 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT Sbjct: 746 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 805 Query: 841 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS 900 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS Sbjct: 806 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS 865 Query: 901 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE 960 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE Sbjct: 866 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE 925 Query: 961 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD 1020 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD Sbjct: 926 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD 985 Query: 1021 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK 1080 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK Sbjct: 986 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK 1045 Query: 1081 EKV 1083 EKV Sbjct: 1046 EKV 1048 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 127 bits (320), Expect = 4e-29 Identities = 188/836 (22%), Positives = 281/836 (33%), Gaps = 88/836 (10%) Query: 95 PVVVRPYPQVQMLSTHHAVASATP--VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSR 152 P P P +T + +P T PP TP+ P++ + PP T PS Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT----TPPPTTTPSP 1456 Query: 153 PIA----PAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN 208 PI+ P P +T S P P T T + P T P I Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS----PPTTTPITPPA 1512 Query: 209 VQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP---TSQLPNAATAQPAV 265 ++ + P PP + P S TT + P T+ LP T P Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPP------TTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566 Query: 266 QHIIHQPIQSRP-PVTTSNAIPPAVVATV-SATRAQSPVITTTAAHATDSALSRPTLSIQ 323 P + P P TT+ PP + T T SP TTT + S PT + Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626 Query: 324 HPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPI 383 PP++ ++ T T P P TP T I +T TP T + Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTP--PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP 1684 Query: 384 LATNTIPSATTAGSVSHTQAPTSTIVTMTVPSH-SSHATAVTTSNIPVAKVVPQQITHTS 442 + T P TT + S T P+S I T T PS ++ + TT P P T T Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744 Query: 443 PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV-QFQYFLPTYPPSAYPLAA 501 + P + + P+ P T + P VP+ + +L + P+ + Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804 Query: 502 HT-----------YTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQL--M 548 T I+ + P+ G+ + P + M Sbjct: 1805 DTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGL-ICKNEDQKPGGVIPM 1863 Query: 549 TVDASHARHIQ----GIQPAPISTQGIQ-PAPIGTPGI--------QPAPLGTQGIHSAT 595 ++ ++Q QP ++T + P P T I P P GTQ + T Sbjct: 1864 AFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQ-TPTTT 1922 Query: 596 PINTQGL---QPAPMGTQQP--QPEGKTSAVVLADGATIVANPISNPFSAAPAAT----- 645 PI T P P GTQ P P T+ V T P + P + T Sbjct: 1923 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1982 Query: 646 TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIP-PQPPDVASPRVESSMR 704 T QT + + T +P P+ + P T + T+ P P P +P Sbjct: 1983 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2041 Query: 705 STSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIA 764 +T+ +P P ++ + T TV+ T + PT T PT PT Sbjct: 2042 TTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 2099 Query: 765 AASPPSQPAVALSTIPGA-------VPITPPITTIAAAPP---------PSVTVGGSLSS 808 +P + P +T+ P T PITT P P+ T + ++ Sbjct: 2100 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2159 Query: 809 VLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 V P P P+ V+ P T T +P+ + ++ + P G Sbjct: 2160 VTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2214 Score = 117 bits (294), Expect = 5e-26 Identities = 177/804 (22%), Positives = 256/804 (31%), Gaps = 70/804 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3560 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3561 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3679 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3739 Query: 339 RDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3799 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3859 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT--YTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 3860 TTV-------TPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTT 3907 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 3908 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 3965 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQPQ--PEGKTSAVV 622 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 3966 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4024 Query: 623 LADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 T P + P + T T QT + + T +P P+ + P T Sbjct: 4025 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTT 4083 Query: 678 DGMAVRKTLIP-PQPPDVASPRVESSMRSTS--GSPRPAGAKPKSEIHVSMATPVTVSME 734 + T+ P P P +P +T+ +P P G + + ++ T VT + Sbjct: 4084 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4143 Query: 735 TVSNQNNDQPTIAVP--------PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPIT 786 Q I PT Q P T P P+ T P T Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203 Query: 787 PPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPS 846 PI + + PP + S P+ E P I +A P T +P+ Sbjct: 4204 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT---APT 4260 Query: 847 LALLANNLSMP--TSDLPPGASPR 868 + LS P T+ PPG R Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTR 4284 Score = 115 bits (289), Expect = 2e-25 Identities = 174/804 (21%), Positives = 259/804 (32%), Gaps = 74/804 (9%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 1914 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVT 2092 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSR--------PTLSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2152 Query: 339 RDVTTRITLPSHPALGT---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 2153 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2212 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2272 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 2273 TTV-------TPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTT 2320 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 2321 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 2378 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVV 622 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2437 Query: 623 LADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 T P + P + T T QT + + T +P P+ + P T Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTT 2496 Query: 678 DGMAVRKTLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETV 736 + T+ P P P +P +T+ +P P ++ + T TV+ T Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTP 2555 Query: 737 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-------VPITPPI 789 + PT T PT PT +P + P +T+ P T PI Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614 Query: 790 TTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 840 TT P P+ T + ++V P P P+ V+ P T Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPT 2673 Query: 841 NTVSPSLALLANNLSMPTSDLPPG 864 T +P+ + ++ + P G Sbjct: 2674 GTQTPTTTPITTTTTVTPTPTPTG 2697 Score = 114 bits (285), Expect = 5e-25 Identities = 173/797 (21%), Positives = 257/797 (32%), Gaps = 74/797 (9%) Query: 122 TAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVTVTME--- 177 T P T P G P P + + P P P+ P P T T+ Sbjct: 1898 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1957 Query: 178 ----SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRG 233 + P + I T P+ TT + + + P P + P Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017 Query: 234 AAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 + + T T+ + T P Q + P+TT+ + P T Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTG 2076 Query: 294 SATRAQSPVITTTAAHATDSALSR--------PTLSIQHPPSAAISIQRPAQSRDVTTRI 345 + T +P+ TTT T + T + P Q P + TT Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136 Query: 346 TLPSHPALGT---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATTAGSVSHT 401 P+ GT + T T T T T PI T T+ P+ T G+ + T Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2196 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 P +T T+T + TT+ I V T T + P ++ + Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---- 2252 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS-TIRQYP 518 +P P T++ + T P+ P T TPIT++ + T P Sbjct: 2253 ---TPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304 Query: 519 VSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 Q P + IT T V T Q T P P TQ PI Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362 Query: 578 TPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVLADGATI 629 T P P GTQ + TPI T P P GTQ P P T+ V T Sbjct: 2363 TTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421 Query: 630 VANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRK 684 P + P + T T QT + + T +P P+ + P T + Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTT 2480 Query: 685 TLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQ 743 T+ P P P +P +T+ +P P ++ + T TV+ T + Sbjct: 2481 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQT 2539 Query: 744 PTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-------VPITPPITTIAAAP 796 PT T PT PT +P + P +T+ P T PITT Sbjct: 2540 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598 Query: 797 P---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 847 P P+ T + ++V P P P+ V+ P T T +P+ Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTT 2657 Query: 848 ALLANNLSMPTSDLPPG 864 + ++ + P G Sbjct: 2658 TPITTTTTVTPTPTPTG 2674 Score = 112 bits (279), Expect = 2e-24 Identities = 167/744 (22%), Positives = 245/744 (32%), Gaps = 66/744 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3652 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3653 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3771 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831 Query: 339 RDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3891 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT--YTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 3952 TTV-------TPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTT 3999 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 4000 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 4057 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQPQ--PEGKTSAVV 622 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 4058 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4116 Query: 623 LADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 T P + P + T T QT + + T +P P+ + P T Sbjct: 4117 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTT 4175 Query: 678 DGMAVRKTLIPPQPPD--VASPRVESSMRS----TSGSPRPAGAKPKSEIHVSMATPVTV 731 + T+ P P P +S T+ +P P + P++ S ++P+T Sbjct: 4176 TPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR--STSSPLTE 4233 Query: 732 SMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITT 791 S +S P I + TA PT PT + S P ++ PG P T Sbjct: 4234 STTLLSTL---PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT-PTRGTTTG 4289 Query: 792 IAAAPPPSVTVGGSLSSVLGPPVP 815 ++AP PS + S+ P P Sbjct: 4290 SSSAPTPSTVQTTTTSAWTPTPTP 4313 Score = 111 bits (277), Expect = 4e-24 Identities = 176/803 (21%), Positives = 257/803 (32%), Gaps = 72/803 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2272 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 2273 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2332 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 2333 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 2391 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 2452 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 2505 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 2506 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2563 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 2564 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 2620 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 2678 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737 Query: 624 ADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPATD 678 T P + P + T T QT + + T +P P+ + P T Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTT 2796 Query: 679 GMAVRKTLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVS 737 + T+ P P P +P +T+ +P P ++ + T TV+ T + Sbjct: 2797 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPT 2855 Query: 738 NQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-------VPITPPIT 790 PT T PT PT +P + P +T+ P T PIT Sbjct: 2856 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914 Query: 791 TIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 841 T P P+ T + ++V P P P+ V+ P T Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 2973 Query: 842 TVSPSLALLANNLSMPTSDLPPG 864 T +P+ + ++ + P G Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTG 2996 Score = 111 bits (277), Expect = 4e-24 Identities = 176/803 (21%), Positives = 257/803 (32%), Gaps = 72/803 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 2874 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 2935 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 2988 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 2989 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3046 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 3103 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 3161 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220 Query: 624 ADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPATD 678 T P + P + T T QT + + T +P P+ + P T Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTT 3279 Query: 679 GMAVRKTLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVS 737 + T+ P P P +P +T+ +P P ++ + T TV+ T + Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPT 3338 Query: 738 NQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-------VPITPPIT 790 PT T PT PT +P + P +T+ P T PIT Sbjct: 3339 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397 Query: 791 TIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 841 T P P+ T + ++V P P P+ V+ P T Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3456 Query: 842 TVSPSLALLANNLSMPTSDLPPG 864 T +P+ + ++ + P G Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTG 3479 Score = 111 bits (277), Expect = 4e-24 Identities = 176/803 (21%), Positives = 257/803 (32%), Gaps = 72/803 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3357 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 3418 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 3471 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 3472 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3529 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 3586 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703 Query: 624 ADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKPATD 678 T P + P + T T QT + + T +P P+ + P T Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTT 3762 Query: 679 GMAVRKTLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVS 737 + T+ P P P +P +T+ +P P ++ + T TV+ T + Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPT 3821 Query: 738 NQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-------VPITPPIT 790 PT T PT PT +P + P +T+ P T PIT Sbjct: 3822 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880 Query: 791 TIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 841 T P P+ T + ++V P P P+ V+ P T Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3939 Query: 842 TVSPSLALLANNLSMPTSDLPPG 864 T +P+ + ++ + P G Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTG 3962 Score = 103 bits (257), Expect = 9e-22 Identities = 183/831 (22%), Positives = 271/831 (32%), Gaps = 108/831 (12%) Query: 95 PVVVRPYPQVQMLSTHHAVAS-ATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRP 153 P+ P P ++T + ++P+ T P+ T P + P P+ P+ Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743 Query: 154 IAPAPPSTLS-------LPPKVPGQVTVTMESSIPQASAIPVATISG--QQGHPSNLHHI 204 + PP+T S LPP + ++ P +P+ +G G P N H Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKP-NFHKP 1802 Query: 205 MTTNVQMSIIRSNAPGPPLHIGAS-----HLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA 259 + + PG +I +P G V+ V + + Q P Sbjct: 1803 GGDTELIGDVCG--PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860 Query: 260 TAQPAVQHI---------IHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHA 310 + + QP + TT N PP +P+ TTT Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPT-TMTTTTTENPTPPTT----------TPITTTTTVTP 1909 Query: 311 TDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFS 370 T + PT Q P + TT P+ GT Q T T + Sbjct: 1910 TPT----PT-----------GTQTPTTTPITTTTTVTPTPTPTGT---QTPTTTPITTTT 1951 Query: 371 TGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPV 430 T TP T T I + TT V+ T PT T T P ++ T VT + P Sbjct: 1952 TVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTT--TTVTPTPTPT 2006 Query: 431 AKVVPQQITHTSPRIQPDYPAERSSLIPIS---GHRASPNPVAMETRSDNRPSVPVQFQY 487 P T+ P + P + + P T + + P+ Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--- 2063 Query: 488 FLPTYPPSAYPLAAH--TYTPITSSVS-TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLN 543 T P+ P T TPIT++ + T P Q P + IT T V T Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--T 2121 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI---QPAPLGTQGIHSATPINTQ 600 Q T P P TQ PI T P P GTQ + TPI T Sbjct: 2122 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTT 2180 Query: 601 GL---QPAPMGTQQP--QPEGKTSAVVLADGATIVANPISNPFSAAPAAT-----TVVQT 650 P P GTQ P P T+ V T P + P + T T QT Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240 Query: 651 HSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIP-PQPPDVASPRVESSMRSTSGS 709 + + T +P P+ + P T + T+ P P P +P +T+ + Sbjct: 2241 PTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2299 Query: 710 PRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPP 769 P P ++ + T TV+ T + PT T PT PT +P Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPT 2357 Query: 770 SQPAVALSTIPGA-------VPITPPITTIAAAPP---------PSVTVGGSLSSVLGPP 813 + P +T+ P T PITT P P+ T + ++V P Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417 Query: 814 VPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 P P+ V+ P T T +P+ + ++ + P G Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2467 Score = 103 bits (257), Expect = 9e-22 Identities = 152/686 (22%), Positives = 226/686 (32%), Gaps = 71/686 (10%) Query: 231 PRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP------IQSRPPVTTSNA 284 P + +++ VT PT T + P + P+TT+ Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSR--------PTLSIQHPPSAAISIQRPA 336 + P T + T +P+ TTT T + T + P Q P Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2012 Query: 337 QSRDVTTRITLPSHPALGT---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI-PSA 392 + TT P+ GT + T T T T T PI T T+ P+ Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2072 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAE 452 T G+ + T P +T T+T + TT+ I V T T + P Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132 Query: 453 RSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSS 510 ++ + +P P T++ + T P+ P T TPIT++ Sbjct: 2133 TTTTV-------TPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTT 2180 Query: 511 VS-TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIST 568 + T P Q P + IT T V T Q T P P T Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGT 2238 Query: 569 QGIQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSA 620 Q PI T P P GTQ + TPI T P P GTQ P P T+ Sbjct: 2239 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2297 Query: 621 VVLADGATIVANPISNPFSAAPAAT-----TVVQTHSQSASTNAPAQGSSPRPSILRKKP 675 V T P + P + T T QT + + T +P P+ + P Sbjct: 2298 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTP 2356 Query: 676 ATDGMAVRKTLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSME 734 T + T+ P P P +P +T+ +P P ++ + T TV+ Sbjct: 2357 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-P 2415 Query: 735 TVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-------VPITP 787 T + PT T PT PT +P + P +T+ P T Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474 Query: 788 PITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPL 838 PITT P P+ T + ++V P P P+ V+ P Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PT 2533 Query: 839 ATNTVSPSLALLANNLSMPTSDLPPG 864 T T +P+ + ++ + P G Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTG 2559 Score = 100 bits (249), Expect = 7e-21 Identities = 154/706 (21%), Positives = 229/706 (32%), Gaps = 80/706 (11%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3721 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3840 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 3901 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 3954 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 3955 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012 Query: 459 ISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYP 518 + P+ T P+ P Q PT P T TP + T P Sbjct: 4013 ------TTTPITTTTTVTPTPT-PTGTQ--TPTTTPITTTTTV-TPTPTPTGTQTPTTTP 4062 Query: 519 VSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGT 578 ++ + TG +T + +T P P TQ PI T Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----------TPTPTGTQTPTTTPITT 4111 Query: 579 PGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVLADGATIV 630 P P GTQ + TPI T P P GTQ P P T+ V T Sbjct: 4112 TTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170 Query: 631 ANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ 690 P + P + TTV T + + + P +S P + + Sbjct: 4171 QTPTTTPIT---TTTTVTPTPTPTGTQTGPPTHTSTAP-------------IAELTTSNP 4214 Query: 691 PPDVASPRVESSMRS--TSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAV 748 PP+ ++P+ S S T + + P E+ S A P T + T ++ + T++ Sbjct: 4215 PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM-TSTAPPSTPTAPTTTSGGH---TLSP 4270 Query: 749 PPTAQQPPPTIP---TMIAAASPPSQPAVALSTIPGAVPITPPITT 791 PP+ PP P T ++S P+ V +T P P++T Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST 4316 Score = 90.9 bits (224), Expect = 6e-18 Identities = 155/736 (21%), Positives = 236/736 (32%), Gaps = 100/736 (13%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3708 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3767 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3768 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3886 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3887 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3946 Query: 339 RDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 3947 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4006 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 4007 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4066 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT--YTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 4067 TTV-------TPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTT 4114 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 4115 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 4172 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKT------SAV 621 PI T P P GTQ + P +T A + T P PE T ++ Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQ---TGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSS 4229 Query: 622 VLADGATIVAN--PISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDG 679 L + T+++ P S AP +T T + T +P ++ P + T G Sbjct: 4230 PLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTG 4289 Query: 680 MAVRKT----------LIPPQPPDVASPRVESSMRSTSGSPRPAGA-----------KPK 718 + T P P +++P + +R+T P P+ P Sbjct: 4290 SSSAPTPSTVQTTTTSAWTPTPTPLSTPSI---IRTTGLRPYPSSVLICCVLNDTYYAPG 4346 Query: 719 SEIH----------VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASP 768 E++ V+ + T+ S + PT PT P + PT +S Sbjct: 4347 EEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT----PT---PSKSTPTPSKPSST 4399 Query: 769 PSQPAVALSTIPGAVP 784 PS+P PG P Sbjct: 4400 PSKPT------PGTKP 4409 Score = 87.4 bits (215), Expect = 7e-17 Identities = 108/413 (26%), Positives = 148/413 (35%), Gaps = 35/413 (8%) Query: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 +T P T P S + P P+ P+ PP+T PP +T T Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP-----ITTTTTPPP 1450 Query: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 + P++T + P+ TT + P PP + P Sbjct: 1451 TTTPSPPISTTTTPP--PTTTPSPPTTTPSPP---TTTPSPPTTTTTTPPP------TTT 1499 Query: 241 SSSKVTTVLRP---TSQLPNAATAQPAVQHIIHQPIQSRP-PVTTSNAIPPAVVATVSAT 296 S TT + P T+ LP T P P + P P TT+ PP T+ T Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559 Query: 297 RAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQS-RDVTTRITLPSHPALGT 355 SP TTT + S PT + PP+ + P + TT T P P T Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP--PPTTT 1617 Query: 356 PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV-P 414 P T +T P T +P T T P TT S T P+ I T T P Sbjct: 1618 PSPPTTTPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP 1676 Query: 415 SHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETR 474 ++ ++ +TT+ P +T SP P P ++ P S SP P M T Sbjct: 1677 PTTTPSSPITTTPSPPTTT----MTTPSPTTTPSSPI-TTTTTPSSTTTPSPPPTTMTTP 1731 Query: 475 S-DNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNS 526 S PS P LP S+ PL T TP+ S++ P S P + Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSS-PL---TTTPLPPSITPPTFSPFSTTTPTT 1780 Score = 74.3 bits (181), Expect = 6e-13 Identities = 89/389 (22%), Positives = 133/389 (34%), Gaps = 34/389 (8%) Query: 490 PTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQL 547 PT PS P + T P T S +T P P+ IT T +T Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461 Query: 548 MTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPM 607 T + P+P +T P+P T P P T + TPI Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTT---PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518 Query: 608 GTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPR 667 T P P T+ T + P + P + + TT+ T + S P ++P Sbjct: 1519 PTTTPSPP--TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP---PTTTTTPP 1573 Query: 668 PSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMAT 727 P+ P T + T+ PP +P ++ +T+ P P + ++ T Sbjct: 1574 PTTTPSPPTTTTPSP-PTITTTTPPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPITPPT 1630 Query: 728 PVTVSMETVSNQNNDQPTIAVPPTAQQPPPTI----PTMIAAASPP-----SQPAVALST 778 T T + T PPT PPT P + +PP S P + Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690 Query: 779 IPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPL 838 P TP TT ++P + T S ++ PP P ++ +PP Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP- 1749 Query: 839 ATNTVSPSLALLANNLSMPTSDLPPGASP 867 T T SP + T+ LPP +P Sbjct: 1750 -TTTSSP----------LTTTPLPPSITP 1767 Score = 71.2 bits (173), Expect = 5e-12 Identities = 112/478 (23%), Positives = 161/478 (33%), Gaps = 90/478 (18%) Query: 370 STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP 429 +T +P P +T T+P TT PT+T T T P ++ + +TT+ P Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSP------PTTT--TTTPPPTTTPSPPITTTTTP 1448 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD---NRPSVPVQFQ 486 P T+ P + P S +P+P T + PS P Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTP-SPPTTTPSPPTTTTTTPPPTTTPSPPTT-- 1505 Query: 487 YFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAP--NSAITAQTGVGVASTVHLNP 544 P PP++ T TP + +T P + +P + IT T ST L P Sbjct: 1506 --TPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT-----STTTLPP 1558 Query: 545 MQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQP 604 P+P T P P TP +P T P Sbjct: 1559 TTT---------------PSPPPTTTTTPPPTTTP---------------SPPTTTTPSP 1588 Query: 605 APMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGS 664 + T P P S T P + P +P TT + T S +T P Sbjct: 1589 PTITTTTPPPTTTPSPPTTT---TTTPPPTTTP---SPPTTTPI-TPPTSTTTLPPTTTP 1641 Query: 665 SPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVS 724 SP P+ P T P PP +P S +T+ +P P P S I + Sbjct: 1642 SPPPTTTTTPPPTT---------TPSPPTTTTP---SPPITTTTTPPPT-TTPSSPI-TT 1687 Query: 725 MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVP 784 +P T +M T P+ P++ T P+ SPP P + P P Sbjct: 1688 TPSPPTTTMTT--------PSPTTTPSSPITTTTTPSSTTTPSPP--PTTMTTPSPTTTP 1737 Query: 785 ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 842 +PP TT+ PP + + S + P+P P P + PL T Sbjct: 1738 -SPPTTTMTTLPPTTTS-----SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWT 1789 Score = 71.2 bits (173), Expect = 5e-12 Identities = 109/471 (23%), Positives = 157/471 (33%), Gaps = 85/471 (18%) Query: 316 SRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPV 375 S PT + PP++ ++ TT T P P TP + T T TP Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP--PPTTTPSPPITT--------TTTPP 1449 Query: 376 AAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVP 435 T +P ++T T P TT S T P+ T + P T TT+ P P Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPP-TTTPSPPTTTPSPP------TTTTTTPPPTTTPSP 1502 Query: 436 QQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPS 495 T +P PA ++L P + +P+P T T PP+ Sbjct: 1503 PTTTPITP------PASTTTLPPTT----TPSPPTTTTT----------------TPPPT 1536 Query: 496 AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ----TGVGVASTVHLNPMQLMTVD 551 P + T TPIT ST P + +P T T +T +P + T Sbjct: 1537 TTP-SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT 1595 Query: 552 ASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 P P +T P+P T P P T + TPI T Sbjct: 1596 -----------PPPTTT----PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671 P P T T P + P +P TT + +T P S + Sbjct: 1641 PSPPPTT---------TTTPPPTTTP---SPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688 Query: 672 RKKPATDGMAVRKTLIPPQPPDV-ASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVT 730 P T T+ P P +SP ++ S++ +P P + + +P T Sbjct: 1689 PSPPTT-------TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741 Query: 731 VSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG 781 +M T+ P P PPT + + P+ P V L G Sbjct: 1742 TTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF--STTTPTTPCVPLCNWTG 1790 Score = 68.6 bits (166), Expect = 3e-11 Identities = 85/373 (22%), Positives = 121/373 (32%), Gaps = 39/373 (10%) Query: 575 PIGTPGIQPAPLGTQGIHSAT---PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA 631 P TP P P T + T P T P P T P T+ T + Sbjct: 1402 PTTTPS--PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP----PPTTTPS 1455 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTNAPAQGSS----PRPSILRKKPATDGMAVRKTLI 687 PIS + P T T + S T P+ ++ P P+ P T + Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT------PIT 1509 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA 747 PP P S +T+ + P P TP+T T + P+ Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPT----TTPITPPTSTTTLPPTTTPS-P 1564 Query: 748 VPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLS 807 P T PPPT + PS P + +T P +PP TT PPP+ T + Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT-TTTPPPTTTPSPPTT 1623 Query: 808 SVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 867 + + PP + P P + P T T SP + T+ PP +P Sbjct: 1624 TPITPPTSTTTLPPTTTPSP--PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP 1681 Query: 868 RKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLV-----KAEKRKSPPKEYIDEEGVR 922 I+T T +T +T S + + SPP + Sbjct: 1682 SSP-------ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734 Query: 923 YVPVRPRPPITLL 935 P P +T L Sbjct: 1735 TTPSPPTTTMTTL 1747 Score = 54.3 bits (129), Expect = 6e-07 Identities = 38/129 (29%), Positives = 50/129 (38%), Gaps = 9/129 (6%) Query: 745 TIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGG 804 T + P T PPPT T + + PS P +T P +PPITT PPP+ T Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITT-TTTPPPTTTPSP 1456 Query: 805 SLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMP------T 858 +S+ PP P S PP T T P + + P T Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPS--PPTTTTTTPPPTTTPSPPTTTPITPPAST 1514 Query: 859 SDLPPGASP 867 + LPP +P Sbjct: 1515 TTLPPTTTP 1523 Score = 43.9 bits (102), Expect = 8e-04 Identities = 43/182 (23%), Positives = 59/182 (32%), Gaps = 11/182 (6%) Query: 730 TVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMI-AAASPPSQPAVALSTIPGAVPITPP 788 T S T + T +PPT PPT T + PS P +T P +PP Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457 Query: 789 ITTIAAAPP-----PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTV 843 I+T PP P T ++ PP PP +T T+ Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL 1517 Query: 844 ----SPSLALLANNLSMP-TSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTA 898 +PS P T+ PP +P P + T T +T +T Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577 Query: 899 KS 900 S Sbjct: 1578 PS 1579 Score = 41.6 bits (96), Expect = 0.004 Identities = 36/147 (24%), Positives = 51/147 (34%), Gaps = 7/147 (4%) Query: 759 IPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGP-----P 813 I T + PS P + +T+P +PP TT PPP+ T +++ P P Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTT-TTPPPTTTPSPPITTTTTPPPTTTP 1454 Query: 814 VPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRK 873 P I P P + P T T SP T+ PP +P P Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP-TTTTTTPPPTTTPSPPTTTPITPPAS 1513 Query: 874 QQHVISTEEGDMMETNSTDDEKSTAKS 900 + T T +T +T S Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPS 1540 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 124 bits (310), Expect = 6e-28 Identities = 221/1002 (22%), Positives = 372/1002 (37%), Gaps = 144/1002 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR--EEKQEP 95 P T + + + +A+ ++ L A + S+ + + +S+ + E P Sbjct: 2339 PLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTP 2398 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL-SFSEGLMKPPPKPTMPSRPI 154 + P + ++S+ + S TPV + P T A + +EG P P+ + P+ Sbjct: 2399 LTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 2458 Query: 155 APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIM---TTNVQM 211 A P ST + G ++ T P ++ P+ T + P+ I+ +T + Sbjct: 2459 ASMPVSTTPVVSSEAGTLSTT-----PVDTSTPMTTSTEASSSPTTAEDIVVPISTASEG 2513 Query: 212 SIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNA-ATAQPAVQHIIH 270 S + ++ P + AS + V S+S V T +S +A T+ P + Sbjct: 2514 STLLTSIPVSTTPV-ASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEG 2572 Query: 271 Q-PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA 329 P++S P T A A + + PV T+T ++ + ++ I P + Sbjct: 2573 STPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVS 2632 Query: 330 ISIQR------PAQSRDVTTRITLPSHP----ALGTPKQQLHTMAQKTIFSTGTPVAAAT 379 S+ P S + +T T P T T A+ + T TP +T Sbjct: 2633 TSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERST 2692 Query: 380 -VAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTS---------NIP 429 + IL + T+ + + A ++S T TST VT + + SS TA TS + P Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTP 2752 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPIS-GHRASPNPVAMETRSDNRPSVPVQFQYF 488 + ++ + S + IP++ AS +P E S S P + Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTS-MPTSTPSETSTP 2811 Query: 489 LPTYPPSAYPLAAH-----------TYTPITSSVSTIRQ--------YPVSAQAPNSAIT 529 L + P + P+A+ T TP+T+S P+S + S + Sbjct: 2812 LTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLL 2871 Query: 530 AQTGVGV-------ASTVHLNPMQLM------TVDASHARHIQGIQPAPISTQGIQPAPI 576 V AST+ P+ T +S +G PIST P+ + Sbjct: 2872 TSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTS-MPIST----PSEV 2926 Query: 577 GTP------------GIQPAPLGTQGIHSATPINTQG-LQPAPM---GTQQP---QPEGK 617 TP G + + L T + + TP+ T +P GT P E + Sbjct: 2927 STPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERR 2986 Query: 618 TSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTN------------APAQGSS 665 T ++ VA+ ++ S PA T+ T S AS++ P++GS+ Sbjct: 2987 TPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGST 3046 Query: 666 PRPSI-LRKKPAT--DGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPA-----GAKP 717 P SI + P + + T + P V S V SS G+ P G+ P Sbjct: 3047 PLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTP 3106 Query: 718 KSEIHVSMATPVTVS-METVSNQNNDQPTIAVPPT-AQQPPPTIPTMIAAASPPSQPAVA 775 + + VS TPVT S + T+S D T T A P T S PS+ + Sbjct: 3107 LTGVPVS-TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTP 3165 Query: 776 LSTIP--------------GAVPI--TPPITTIAAAPP---------PSVTVGGSLSSVL 810 L+ +P A P+ + P+TT A P+ T ++ + Sbjct: 3166 LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLT 3225 Query: 811 GPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK 870 PV V + PV + PL T+T + S A SMPTS G++P Sbjct: 3226 SVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTS 3285 Query: 871 PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPP 912 +++ E + T D T+ + ++ SPP Sbjct: 3286 MPVSTTTVASSETSTLSTTPAD----TSTPVTTYSQASSSPP 3323 Score = 121 bits (303), Expect = 4e-27 Identities = 206/925 (22%), Positives = 347/925 (37%), Gaps = 92/925 (9%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQ--SREEKQEP 95 P T + + + +ANS ++ L + +E S+ + +S++ + + P Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTP 2752 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL-SFSEGLMKPPPKPTMPSRPI 154 + + + S+ + S T V + P T A + +E P P+ S P+ Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812 Query: 155 APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P + + G ++ T P ++ PV T + P+ I+ I Sbjct: 2813 TSMPVNHTPVASSEAGTLSTT-----PVDTSTPVTTSTKASSSPTTAEGIVVP------I 2861 Query: 215 RSNAPGPPL--HIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA--TAQPAVQHIIH 270 + + G L I S P ++ A+ +S++ V T + T+ ++ T I Sbjct: 2862 STASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921 Query: 271 QPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAI 330 P + P+T+ V + ++T + +PV T T + A S PT + ++ Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTA----EGTSM 2977 Query: 331 SIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVA---PILATN 387 I P + R T +++ + P + L +T T TPV +T A P A Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTL----SRTPADTSTPVTTSTEASSSPTTAEG 3033 Query: 388 T-IPSATTA-GSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRI 445 T IP +T + GS T P ST + +P S+ +T SN PV +T T Sbjct: 3034 TGIPISTPSEGSTPLTSIPVST-TPVAIPEASTLSTTPVDSNSPV-------VTSTEVSS 3085 Query: 446 QPDYPAERSSLIPISGHRASPNP---VAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH 502 P PAE +S+ PIS + P V + T ++ + T P AH Sbjct: 3086 SPT-PAEGTSM-PISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAH 3143 Query: 503 TYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVAS---TVHLNPMQLMT-----VDASH 554 + + S P P + + T + V+S T+ P+ T +A+ Sbjct: 3144 SSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATS 3203 Query: 555 ARHIQGIQ-PAPISTQGIQP---APIGTPGI---QPAPLGTQGIHSATPINTQ----GLQ 603 + +G P ++G+ P P+ + + + L T + S TP+ T Sbjct: 3204 STTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP 3263 Query: 604 PAPMGTQQPQP---EGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNA 659 P GT P EG T + T VA+ ++ S PA T T V T+SQ++S+ Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPP 3323 Query: 660 PAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKS 719 A G+S S ++G + P V+S E+S ST+ + Sbjct: 3324 IADGTSMPTSTY-----SEGSTPLTNMSFSTTPVVSS---EASTLSTTPVDTSTPVTTST 3375 Query: 720 EIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI 779 E +S T S+ T S P+ P A P T P + + + S V +T+ Sbjct: 3376 EASLSPTTAEGTSIPTSS------PSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTL 3429 Query: 780 PGAVPITPPITTIAAAP--PPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPP 837 TIA P S T GS + P E + PV P Sbjct: 3430 VTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTT-PVDTSTP 3488 Query: 838 LATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTD----- 892 + T++ + S A SMPTS G++P +++ E + T D Sbjct: 3489 VTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFV 3548 Query: 893 ---DEKSTAKSLLVKAEKRKSPPKE 914 + S++ + L R S P E Sbjct: 3549 TSSSQASSSPATLQVTTMRMSTPSE 3573 Score = 118 bits (295), Expect = 3e-26 Identities = 193/906 (21%), Positives = 330/906 (36%), Gaps = 80/906 (8%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR--EEKQEP 95 P T + + +ANS ++ L N +E S+ + +S+ + E P Sbjct: 984 PLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTP 1043 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS-EGLMKPPPKPTMPSRPI 154 + P + S+ + S TP + P + A S + +G P + S P+ Sbjct: 1044 LTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPL 1103 Query: 155 APAP----------PSTLSLPP---KVPGQVTVTMESSIPQASAIPVATISGQQGHPSNL 201 P STLS P +P + SS A + T +G Sbjct: 1104 TSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLA 1163 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA 261 ++T + +S + P+ + + A++ +++VT++ PTS P + Sbjct: 1164 SMPVSTTLVVSSEANTLSTTPVD-SKTQVATSTEASSPPPTAEVTSM--PTST-PGERST 1219 Query: 262 QPAVQHIIHQPIQSRPPVTTSNA-IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL 320 + H P+ S T S + + + T SA + SP + T + TL Sbjct: 1220 PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTL 1279 Query: 321 SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATV 380 P S + + P S +TT + T A+ T T T T Sbjct: 1280 LTSIPVSTTL-VTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTP 1338 Query: 381 APILATNTIPSATTAGSV-SHTQAPTSTIVTMTVPSHSSHATAVTTS---NIPVAKVVPQ 436 + NT A++A S+ S T ST VT + + SS T+ TS + P P Sbjct: 1339 LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP- 1397 Query: 437 QITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSA 496 +T P +E S+L ++P + E S + + P+ + Sbjct: 1398 -LTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP 1456 Query: 497 YPLAAHTYTPITSS-VSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHA 555 + TP+ +S ST+ PV + NS + T V + T ++ + + Sbjct: 1457 LKSIPVSNTPVANSEASTLSTTPVDS---NSPVVTSTAVSSSPTPAEGTSIAISTPSEGS 1513 Query: 556 RHIQGIQPAPISTQGIQPAPIG----TPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 + I P+ST + + I TP + P+ T S++P G M T Sbjct: 1514 TALTSI---PVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS---MQTST 1567 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPS-- 669 EG T L +V + +N S P + T S AS++ A+GSS S Sbjct: 1568 -YSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTP 1626 Query: 670 -----ILRKKPA--TDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIH 722 +L P T + + + P D SP + S+ S+S +P + P S + Sbjct: 1627 SEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTST-Y 1685 Query: 723 VSMATPVT-VSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG 781 TP+T +++ T ++ T++ P P T T A +SP + ++ P Sbjct: 1686 TEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTE-ARSSPTTSEGTSM---PN 1741 Query: 782 AVPI--TPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLA 839 + P T P+T+I + P ++ S S P+ P+ Sbjct: 1742 STPSEGTTPLTSIPVSTTPVLSSEASTLSAT--------------------PIDTSTPVT 1781 Query: 840 TNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAK 899 T+T + S A S+PTS L G +P +++ E + T D Sbjct: 1782 TSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVT 1841 Query: 900 SLLVKA 905 S V + Sbjct: 1842 STAVSS 1847 Score = 117 bits (293), Expect = 6e-26 Identities = 191/931 (20%), Positives = 343/931 (36%), Gaps = 104/931 (11%) Query: 81 SSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL-SFSEG 139 S++ + E P+ P +++ S+ TPV ++ P A + +EG Sbjct: 203 STTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEG 262 Query: 140 LMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPS 199 P+ S P+ P S + + ++ T P A+ IPV T + P+ Sbjct: 263 PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTT-----PAATNIPVITSTEASSSPT 317 Query: 200 NLHHIM---TTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLP 256 +T + S ++ P + + S + + V +S+ VTT P+S LP Sbjct: 318 TAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMST-LSITPVDTSTLVTTSTEPSS-LP 375 Query: 257 NAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALS 316 A A + + + P+T V ++ ++T + PV + T A S Sbjct: 376 TTAEATSMLTSTLSE---GSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASS 432 Query: 317 RPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVA 376 PT + +I+ P++ T + + + P + L T + T Sbjct: 433 SPTTA----EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTE 488 Query: 377 AATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNI----PVAK 432 A++ P N++P++T S P +++ T+P SS A+ ++T+ + PV Sbjct: 489 ASSSPPTAEVNSMPTSTP----SEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTT 544 Query: 433 VVPQQITHTSPR---IQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFL 489 + T+P I P+E S+ P++ S V + + + + P F+ Sbjct: 545 SSEASSSSTTPEGTSIPTSTPSEGST--PLTNMPVSTRLV-VSSEASTTSTTPADSNTFV 601 Query: 490 PTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN---PMQ 546 T ++ T + +S + R +++ + ++ + A + ST ++ P+ Sbjct: 602 TTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT 661 Query: 547 LMTVDASHARHIQGIQ-PAPISTQGIQPA---PIGTPGI---QPAPLGTQGIHSATPINT 599 T S + +G P T+G P P+ T + + + L T + ++TP+ T Sbjct: 662 TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTT 721 Query: 600 QG--------LQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTH 651 A M T P EG T + T++ + ++ S P T+ T Sbjct: 722 STEASSSPTTADGASMPTSTPS-EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITT 780 Query: 652 SQSASTN------------APAQGSSPRPSI---LRKKPATDGMAVRKTLIPPQPPDVAS 696 S AS + P++GS SI + + + + T + P S Sbjct: 781 STEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTS 840 Query: 697 PRVESSMRSTSGSPRPA-----GAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPT 751 V SS G+ P G P + + VS T ++ T+S D T T Sbjct: 841 TEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNST 900 Query: 752 -AQQPPPTIPTMIAAASPPSQPAVALSTIP--------------GAVPI---TPPITTIA 793 A+ P T S P + + L+++P A P+ TP T+ Sbjct: 901 EARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE 960 Query: 794 AAPPPSVTVGGSLSS---------VLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVS 844 A P+ G S+ + + PV V PV + PL T+T + Sbjct: 961 ATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEA 1020 Query: 845 PSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEK-----STAK 899 S A SMPTS G++P + ++++ E + T D S A Sbjct: 1021 SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQAS 1080 Query: 900 SLLVKAEKRKSPPKEYID-EEGVRYVPVRPR 929 S A+ P Y + + VPV R Sbjct: 1081 SSSTTADGTSMPTSTYSEGSTPLTSVPVSTR 1111 Score = 112 bits (280), Expect = 2e-24 Identities = 215/946 (22%), Positives = 353/946 (37%), Gaps = 98/946 (10%) Query: 39 STGLSQAP---SQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR--EEKQ 93 ST L+ P + +A+S L A + S+ S+ + +S+Q+ E Sbjct: 1513 STALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGS 1572 Query: 94 EPVVVRPYPQVQMLSTHHAVASATPV--------------AVTAPPAHLTPAVPLSFSEG 139 P+ P + ++S+ S TP+ + TA + +T + P S Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL 1632 Query: 140 LMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQ--VTVTMESSIP---QASAIPVATISGQ 194 L P T P+A STLS P +T T SS P + +++P +T + + Sbjct: 1633 LTSIPVSTT----PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT-E 1687 Query: 195 QGHPSNLHHIMTTNVQMSIIRSNAPGP---PLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251 P + TT V S I + + P + S R + + +S +T Sbjct: 1688 GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEG 1747 Query: 252 TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHAT 311 T+ L + + V + S P+ TS + + AT S T A+ I T Sbjct: 1748 TTPLTSIPVSTTPVLSSEASTL-SATPIDTSTPVTTSTEATSSPTTAEGTSIPT------ 1800 Query: 312 DSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFST 371 S LS + P + + S TT + S T T A+ T +T Sbjct: 1801 -STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAT 1859 Query: 372 GTPVAAATVAPIL--ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP 429 TP +T + +T T+ S+ T ++S T A TST VT T SS T S++P Sbjct: 1860 STPSEGSTALTSIPVSTTTVASSET-NTLSTTPAVTSTPVT-TYAQVSSSPTTADGSSMP 1917 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPN-PVAMETRSDNRPSVPVQFQYF 488 + + TS + A S + +S A PV +++ + P+ Sbjct: 1918 TSTPREGRPPLTSIPVSTTTVAS-SEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMP 1976 Query: 489 LPTYPPSAYPLAA---HTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 P Y + PL + T ++S ST+ PV P A T+ G +T + Sbjct: 1977 TPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTP--ATTSTEGSSSPTTAGGTSI 2034 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPA 605 Q T + + G+ P+ST + + T P TQ +S ++ + + Sbjct: 2035 QTST-PSERTTPLAGM---PVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS 2090 Query: 606 PMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA-ATTVVQTHSQSASTNAPAQGS 664 M P EG + T VA+P ++ S P + + V T ++ +S+ P +G+ Sbjct: 2091 SMTISAPS-EGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGT 2149 Query: 665 SPRPSIL--RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIH 722 S + S R+ P T M V T++ S++ + S +P Sbjct: 2150 SMQTSTYSDRRTPLTS-MPVSTTVV-----------ASSAISTLSTTP------------ 2185 Query: 723 VSMATPVTVSMETVSNQNNDQ--------PTIAVPPTAQQPPPTIPTMIAAASPPSQPAV 774 V +TPVT S E S+ + P+ P P T+P + + AS S V Sbjct: 2186 VDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPV 2245 Query: 775 ALST-IPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVS 833 ST + + T TT P+ T+ + + PV V PV Sbjct: 2246 DTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVD 2305 Query: 834 AVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDD 893 + P T+T + S A SMPTS G +P + ++++ E + T D Sbjct: 2306 SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADT 2365 Query: 894 EK-----STAKSLLVKAEKRKSPPKEYID-EEGVRYVPVRPRPPIT 933 S A S A+ P Y + + VPV P ++ Sbjct: 2366 STPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVS 2411 Score = 111 bits (278), Expect = 3e-24 Identities = 200/899 (22%), Positives = 328/899 (36%), Gaps = 133/899 (14%) Query: 103 QVQMLSTHHAVASATPVAVTAPPAHLT-PAVPLSFSEGLMKPPPKPTMPSRPIAPAPPST 161 Q Q LS H SA A ++ P + LS S P+ T + P Sbjct: 51 QCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTN-----PEMTSIESSVTSDTPG- 104 Query: 162 LSLPPKVPGQVTVTMESSIPQASAIPVATI-SGQQGHPSNLHHIMTTNVQMSIIRSNAPG 220 +S P + T ES+ + P +T + P M+T + SI + A Sbjct: 105 VSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMA-- 162 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQL------PNAATAQPAVQHIIHQPIQ 274 + + LP A ++ ++T L ++Q P + T + P+ Sbjct: 163 ---FVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLT 219 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 S P T A A+ + +PV + A ++ + P+LS P + + R Sbjct: 220 SMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTR 279 Query: 335 P------AQSRDVTTRITLPSHPAL----GTPKQQLHTMAQKTIFSTGTPVAAATVAPIL 384 S + +T T P+ + T T A+ T T T +T Sbjct: 280 MPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTST 339 Query: 385 ATNTIPSATT-AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTS--------------NIP 429 +T+P AT+ ++S T TST+VT + S TA TS N+P Sbjct: 340 PASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMP 399 Query: 430 VAKV-VPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYF 488 V+ + V T+ I D S + AS +P E S S P + Sbjct: 400 VSTILVASSEASTTSTIPVD-----SKTFVTTASEASSSPTTAEDTS-IATSTPSEGSTP 453 Query: 489 LPTYPPSAYPLAAHTYTPI-TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQL 547 L + P S P+A+ + + T+ V + Q S +A +S TA+ ST P + Sbjct: 454 LTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTST----PSEG 509 Query: 548 MTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT----QGLQ 603 T P+++ + P+ + + + L T + ++TP+ T Sbjct: 510 ST---------------PLTSMSVSTMPVASS--EASTLSTTPVDTSTPVTTSSEASSSS 552 Query: 604 PAPMGTQQP---QPEGKTSAVVLADGATIVANPISNPFSAAPA-ATTVVQTHSQSASTNA 659 P GT P EG T + +V + ++ S PA + T V T S+++S++ Sbjct: 553 TTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSST 612 Query: 660 PAQGSSPRPSILRKKPAT-DGMAVRKTLIPPQ--------PPDVASPRVESSMRSTSGSP 710 A+G+S S ++ T M+V TL+ P D +P V +S +TS S Sbjct: 613 TAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTP-VTTSTEATSSST 671 Query: 711 RPAGAKPKSEIHVSMATPVT-VSMETVSNQNNDQPTIAVPPTAQQPPPTI-------PTM 762 G + + +TP+T + + T +++ T++ P P T PT Sbjct: 672 TAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTT 731 Query: 763 IAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVT-------VGGSLSSVLGPPVP 815 AS P+ ST ++P++ + T + A S T + S + P Sbjct: 732 ADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTT 791 Query: 816 E-----IKVKEEVEPMDIMRPVSAVP------------------PLATNTVSPSLALLAN 852 E I E P+ PVS P P+ T+T S A Sbjct: 792 EGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAE 851 Query: 853 NLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSP 911 SMPTS G +P +++T + T D T+ + E R SP Sbjct: 852 GTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD----TSTPVTNSTEARSSP 906 Score = 100 bits (248), Expect = 1e-20 Identities = 194/864 (22%), Positives = 320/864 (37%), Gaps = 102/864 (11%) Query: 46 PSQIANSGSAGLIN-PAATVNDESGRDSEVSAREHMSSSSSLQSRE-------------- 90 P+ + GS L P +T+ S DS +SA +S+ S E Sbjct: 3155 PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPT 3214 Query: 91 ----EKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS----EGLMK 142 E P+ P + S+ ++ S TPV P LT + S S EG Sbjct: 3215 STPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP---LTTSTEASSSPPTAEGTSM 3271 Query: 143 PPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLH 202 P P+ S P+ P ST + V T T+ S+ P ++ PV T S P Sbjct: 3272 PTSTPSEGSTPLTSMPVSTTT----VASSETSTL-STTPADTSTPVTTYSQASSSPP--- 3323 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 I + S P ++ S P ++ A+ +S++ V T T+ A+ Sbjct: 3324 -IADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS--TEASLS 3380 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPA----VVATVSATRAQSPVITTTAAHATDSALSRP 318 P P S TT A P VV++ T + +PV + T + A S P Sbjct: 3381 PTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSP 3440 Query: 319 TL--------SIQHPPSAAISIQ----RPAQSRDVTTRITLP---SHPAL-GTPKQQLHT 362 T+ S S +SI P S + +T T P S P +P T Sbjct: 3441 TIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPT 3500 Query: 363 MAQKTIFSTGTPVAAATVAPILATNTIPSATT-AGSVSHTQAPTSTIVTMTVPSHSSHAT 421 A+ T T T +T + +T P A++ A ++S T ++T VT + + SS AT Sbjct: 3501 TAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPAT 3560 Query: 422 A-VTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 VTT + +T + + Y + P + PV T+S++ P+ Sbjct: 3561 LQVTTMRMSTPSEGSSSLT--TMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPT 3618 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 P + T + PL T P++++ TI + ++ P + T V ++ V Sbjct: 3619 PPEVITLPMSTPSEVSTPL---TIMPVSTTSVTISEAGTASTLP---VDTSTPVITSTQV 3672 Query: 541 HLNPMQLMTVDASHARHIQGIQP---APISTQGI---QPAPIGTPGI---QPAPLGTQGI 591 +P+ +G P P+ST + + + + TP + P T+ I Sbjct: 3673 SSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAI 3732 Query: 592 HSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTV-VQT 650 S+ +++ M P +L + P S+ S T++ + T Sbjct: 3733 SSSATLDS-----TTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTT 3787 Query: 651 HSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSG-S 709 S+ +S+ +G++ P T + T + P V SP S++ + G + Sbjct: 3788 ASEGSSSPTTLEGTTTMP-----MSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDT 3842 Query: 710 PRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPP 769 P K+ A T+ + S ++ T+ V T P + P A++PP Sbjct: 3843 STPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTL---PTSFPGASIASTPP 3899 Query: 770 SQPAVAL--STIPGAVPITPPITTIAAAPPPSVTVGGSL--SSVLGPPVPEIKVKEEVEP 825 + ST + P P TTI+ SV GS +++ P P +V P Sbjct: 3900 LDTSTTFTPSTDTASTPTIPVATTISV----SVITEGSTPGTTIFIPSTPVTSSTADVFP 3955 Query: 826 MD---IMRPVSAVPPLATNTVSPS 846 + PV L T + S S Sbjct: 3956 ATTGAVSTPVITSTELNTPSTSSS 3979 Score = 91.7 bits (226), Expect = 3e-18 Identities = 168/781 (21%), Positives = 275/781 (35%), Gaps = 121/781 (15%) Query: 72 SEVSAREHMSSSSSL--QSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAP----- 124 +E S+ ++ +SL + E P+ + P + S+ + S TPV + P Sbjct: 3434 TEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS 3493 Query: 125 PAHLTP------AVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMES 178 P + +P ++P S + P + + P+A + STLS P V VT S Sbjct: 3494 PTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTP-VDSNTFVTSSS 3552 Query: 179 ---SIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAA 235 S P + +S S+L ++ ++ ++ ++ P P Sbjct: 3553 QASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTP------------- 3599 Query: 236 AAAVMSSSKVTTVLRPTSQL--PNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 +V S+ VTT + S P T + + P+ P TTS I A A+ Sbjct: 3600 --SVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAST 3657 Query: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353 +PVIT+T ++ T+ I P + + S TTR+T L Sbjct: 3658 LPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVS---TTRVTSSEGSTL 3714 Query: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV 413 TP T TPV +T A +S + ST +++++ Sbjct: 3715 STPS-----------VVTSTPVTTSTEA----------------ISSSATLDSTTMSVSM 3747 Query: 414 PSH-SSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAME 472 P S+ T + S PV + P+ T P P+ +S+ + S +P +E Sbjct: 3748 PMEISTLGTTILVSTTPVTRF-PESST-------PSIPSVYTSMSMTTASEGSSSPTTLE 3799 Query: 473 TRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQT 532 + T P S T + ++ ++T+ P+S +P+ A T T Sbjct: 3800 GTT---------------TMPMS-------TTSERSTLLTTVLISPISVMSPSEASTLST 3837 Query: 533 GVGVASTVHLN---------PMQLMTVDASHARHIQGIQPAPISTQGIQPA-PIGTPGIQ 582 G ST L P ++ T+ S I + P++T + P PG Sbjct: 3838 PPGDTSTPLLTSTKAGSFSIPAEVTTIRIS----ITSERSTPLTTLLVSTTLPTSFPGAS 3893 Query: 583 -----PAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNP 637 P T S +T + A + EG T + +T V + ++ Sbjct: 3894 IASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADV 3953 Query: 638 FSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVAS- 696 F A A + S +T + + S+ K+ T M L S Sbjct: 3954 FPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPST 4013 Query: 697 PRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTI--AVPPTAQQ 754 PR S +TS S A + P + V+ PVT S E+ TI PP Sbjct: 4014 PRTTSRGCTTSASTLSATSTPHTSTSVT-TRPVTPSSESSRPSTITSHTIPPTFPPAHSS 4072 Query: 755 PPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV 814 PPT +P + + T P + P T A P + S+ P V Sbjct: 4073 TPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTST---PTV 4129 Query: 815 P 815 P Sbjct: 4130 P 4130 Score = 60.1 bits (144), Expect = 1e-08 Identities = 105/474 (22%), Positives = 180/474 (37%), Gaps = 67/474 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 P T + + +++ +S + L P+ + ++ E +SSS++L S + Sbjct: 3695 PLTTMPVSTTRVTSSEGSTLSTPSVVTSTPV-----TTSTEAISSSATLDSTT-----MS 3744 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSF--------SEGLMKPPPKPTM 149 V ++ L T V S TPV T P TP++P + SEG P Sbjct: 3745 VSMPMEISTLGTTILV-STTPV--TRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGT 3801 Query: 150 PSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIP--------VATISGQQGHPSNL 201 + P++ + L + ++V S S P +T +G P+ + Sbjct: 3802 TTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEV 3861 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA 261 T +++SI + + ++ LP A++ S+ + T T A+T Sbjct: 3862 -----TTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTP 3916 Query: 262 QPAVQHIIHQPIQSR------------PPVTTSNA-IPPAVVATVSATRAQSPVITTTAA 308 V I + + PVT+S A + PA VS +PVIT+T Sbjct: 3917 TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVS-----TPVITSTEL 3971 Query: 309 HATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTI 368 + ++ S T S A T T PS P T + T A T+ Sbjct: 3972 NTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPR--TTSRGCTTSAS-TL 4028 Query: 369 FSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNI 428 +T TP + +V T + S+ + SHT PT P+HSS + S+ Sbjct: 4029 SATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFP------PAHSSTPPTTSASS- 4081 Query: 429 PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVP 482 V P+ +T + R + P+ R++ P A P +++ + P+VP Sbjct: 4082 --TTVNPEAVTTMTTRTK---PSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVP 4130 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 107 bits (267), Expect = 6e-23 Identities = 162/815 (19%), Positives = 259/815 (31%), Gaps = 64/815 (7%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 132 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 191 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 192 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 302 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 303 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 412 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 462 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 520 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 521 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 580 Query: 512 STIRQ-------YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA 564 +T+++ P + + T P +PA Sbjct: 581 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 640 Query: 565 PISTQGIQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSA 620 P + +G P P T +PAP + P +T +PAP ++ P Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700 Query: 621 VVLADGATIVANPISNPFS----AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 P + P + + P T T +S + P + P P L P Sbjct: 701 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 760 Query: 677 TDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETV 736 G+ KT +P + + +++ R +P A PK + T + +T Sbjct: 761 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA-----TTTEKTT 815 Query: 737 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAP 796 ++ T T Q P T + + + TI + P T A P Sbjct: 816 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET--AKP 873 Query: 797 PPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 831 T +S P P+ K +P +P Sbjct: 874 KDRAT-----NSKATTPKPQKPTKAPKKPTSTKKP 903 Score = 90.9 bits (224), Expect = 6e-18 Identities = 191/926 (20%), Positives = 282/926 (30%), Gaps = 169/926 (18%) Query: 42 LSQAPSQIANSGSAGLINPAATVNDESGRDS-EVSAREHMSSSSSLQSREEKQEPVVVRP 100 ++ PS NS ++ + TVN E+ ++ E + +S+ + +E + Sbjct: 124 INPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181 Query: 101 YPQVQMLSTHHAVASATPVAVTAP--PAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 + T +A TP A T PA TP P PT P P + P Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK------------EPTPTTPKEPASTTP 229 Query: 159 ----PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P+T+ P P + T S P P T + + Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-------------------- 269 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 P P P+ A + TT PT+ Sbjct: 270 ----PAPTT-------PKEPAPTTTKEPAPTTTKSAPTTP-------------------- 298 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 P TT P + T + P TT A + PT + P+A ++ Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KK 355 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 PA T P PA TPK+ P T P T P+ TT Sbjct: 356 PAP--------TTPKEPAPTTPKE---------------PAPTTTKEPSPTTPKEPAPTT 392 Query: 395 AGSVSHT---QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPA 451 S T APT+T T P S TT+ P A P++ T+P+ PA Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPS----PTTTKEP-APTTPKEPAPTTPK----KPA 443 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 + P P P + + P P PT P P TP T Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA------PTTPKETAPTTPKKLTPTTPE- 496 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 + P + + P P +L +PAP + + Sbjct: 497 ---KLAPTTPEKP---------------APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538 Query: 572 QP----APIGTPGIQPAPLGTQGIHSATPINTQGLQP---APMGTQQPQPEGKTSAVVLA 624 P P T +PAP + TP T P AP ++P P Sbjct: 539 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 598 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILR-KKPATDGMAVR 683 T P S PA TT T + AP P P+ + P T Sbjct: 599 LAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 657 Query: 684 KTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQ 743 T P P ++A + +TS P P K + P T + Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 717 Query: 744 PTIA--VPPTAQQPPPTI--------------PTMIAAASPPSQPAVALSTIPGAVPITP 787 PT + PT + P TI PT A + P +P V + P A P Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT--KP 775 Query: 788 PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 847 +TT A + + + P + E + + + + T + Sbjct: 776 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 835 Query: 848 ALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEK 907 L T+ L P + KK +++ E ET D + +K+ K +K Sbjct: 836 PFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKATTPKPQK 889 Query: 908 RKSPPKEYIDEEGVRYVPVRPRPPIT 933 PK+ + + +P R R P T Sbjct: 890 PTKAPKKPTSTKKPKTMP-RVRKPKT 914 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 555 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 664 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 665 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 718 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 719 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 776 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 777 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 829 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 830 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 889 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 890 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 949 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 950 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1009 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1010 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1063 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 107 bits (267), Expect = 6e-23 Identities = 162/815 (19%), Positives = 259/815 (31%), Gaps = 64/815 (7%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 173 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 232 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 233 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 343 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 344 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 453 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 503 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 561 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 562 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 621 Query: 512 STIRQ-------YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA 564 +T+++ P + + T P +PA Sbjct: 622 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 681 Query: 565 PISTQGIQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSA 620 P + +G P P T +PAP + P +T +PAP ++ P Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741 Query: 621 VVLADGATIVANPISNPFS----AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 P + P + + P T T +S + P + P P L P Sbjct: 742 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 801 Query: 677 TDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETV 736 G+ KT +P + + +++ R +P A PK + T + +T Sbjct: 802 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA-----TTTEKTT 856 Query: 737 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAP 796 ++ T T Q P T + + + TI + P T A P Sbjct: 857 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET--AKP 914 Query: 797 PPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 831 T +S P P+ K +P +P Sbjct: 915 KDRAT-----NSKATTPKPQKPTKAPKKPTSTKKP 944 Score = 90.9 bits (224), Expect = 6e-18 Identities = 191/926 (20%), Positives = 282/926 (30%), Gaps = 169/926 (18%) Query: 42 LSQAPSQIANSGSAGLINPAATVNDESGRDS-EVSAREHMSSSSSLQSREEKQEPVVVRP 100 ++ PS NS ++ + TVN E+ ++ E + +S+ + +E + Sbjct: 165 INPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 222 Query: 101 YPQVQMLSTHHAVASATPVAVTAP--PAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 + T +A TP A T PA TP P PT P P + P Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK------------EPTPTTPKEPASTTP 270 Query: 159 ----PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P+T+ P P + T S P P T + + Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-------------------- 310 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 P P P+ A + TT PT+ Sbjct: 311 ----PAPTT-------PKEPAPTTTKEPAPTTTKSAPTTP-------------------- 339 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 P TT P + T + P TT A + PT + P+A ++ Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KK 396 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 PA T P PA TPK+ P T P T P+ TT Sbjct: 397 PAP--------TTPKEPAPTTPKE---------------PAPTTTKEPSPTTPKEPAPTT 433 Query: 395 AGSVSHT---QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPA 451 S T APT+T T P S TT+ P A P++ T+P+ PA Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPS----PTTTKEP-APTTPKEPAPTTPK----KPA 484 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 + P P P + + P P PT P P TP T Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA------PTTPKETAPTTPKKLTPTTPE- 537 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 + P + + P P +L +PAP + + Sbjct: 538 ---KLAPTTPEKP---------------APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579 Query: 572 QP----APIGTPGIQPAPLGTQGIHSATPINTQGLQP---APMGTQQPQPEGKTSAVVLA 624 P P T +PAP + TP T P AP ++P P Sbjct: 580 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 639 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILR-KKPATDGMAVR 683 T P S PA TT T + AP P P+ + P T Sbjct: 640 LAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 698 Query: 684 KTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQ 743 T P P ++A + +TS P P K + P T + Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 758 Query: 744 PTIA--VPPTAQQPPPTI--------------PTMIAAASPPSQPAVALSTIPGAVPITP 787 PT + PT + P TI PT A + P +P V + P A P Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT--KP 816 Query: 788 PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 847 +TT A + + + P + E + + + + T + Sbjct: 817 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 876 Query: 848 ALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEK 907 L T+ L P + KK +++ E ET D + +K+ K +K Sbjct: 877 PFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKATTPKPQK 930 Query: 908 RKSPPKEYIDEEGVRYVPVRPRPPIT 933 PK+ + + +P R R P T Sbjct: 931 PTKAPKKPTSTKKPKTMP-RVRKPKT 955 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 596 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 705 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 706 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 759 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 760 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 817 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 818 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 870 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 871 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 930 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 931 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 990 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 991 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1050 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1051 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1104 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 107 bits (267), Expect = 6e-23 Identities = 162/815 (19%), Positives = 259/815 (31%), Gaps = 64/815 (7%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 284 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 285 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 395 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 396 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 505 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 555 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 613 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 673 Query: 512 STIRQ-------YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA 564 +T+++ P + + T P +PA Sbjct: 674 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 733 Query: 565 PISTQGIQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSA 620 P + +G P P T +PAP + P +T +PAP ++ P Sbjct: 734 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793 Query: 621 VVLADGATIVANPISNPFS----AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 P + P + + P T T +S + P + P P L P Sbjct: 794 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853 Query: 677 TDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETV 736 G+ KT +P + + +++ R +P A PK + T + +T Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA-----TTTEKTT 908 Query: 737 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAP 796 ++ T T Q P T + + + TI + P T A P Sbjct: 909 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET--AKP 966 Query: 797 PPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 831 T +S P P+ K +P +P Sbjct: 967 KDRAT-----NSKATTPKPQKPTKAPKKPTSTKKP 996 Score = 90.9 bits (224), Expect = 6e-18 Identities = 191/926 (20%), Positives = 282/926 (30%), Gaps = 169/926 (18%) Query: 42 LSQAPSQIANSGSAGLINPAATVNDESGRDS-EVSAREHMSSSSSLQSREEKQEPVVVRP 100 ++ PS NS ++ + TVN E+ ++ E + +S+ + +E + Sbjct: 217 INPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 274 Query: 101 YPQVQMLSTHHAVASATPVAVTAP--PAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 + T +A TP A T PA TP P PT P P + P Sbjct: 275 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK------------EPTPTTPKEPASTTP 322 Query: 159 ----PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P+T+ P P + T S P P T + + Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-------------------- 362 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 P P P+ A + TT PT+ Sbjct: 363 ----PAPTT-------PKEPAPTTTKEPAPTTTKSAPTTP-------------------- 391 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 P TT P + T + P TT A + PT + P+A ++ Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KK 448 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 PA T P PA TPK+ P T P T P+ TT Sbjct: 449 PAP--------TTPKEPAPTTPKE---------------PAPTTTKEPSPTTPKEPAPTT 485 Query: 395 AGSVSHT---QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPA 451 S T APT+T T P S TT+ P A P++ T+P+ PA Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPS----PTTTKEP-APTTPKEPAPTTPK----KPA 536 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 + P P P + + P P PT P P TP T Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA------PTTPKETAPTTPKKLTPTTPE- 589 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 + P + + P P +L +PAP + + Sbjct: 590 ---KLAPTTPEKP---------------APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631 Query: 572 QP----APIGTPGIQPAPLGTQGIHSATPINTQGLQP---APMGTQQPQPEGKTSAVVLA 624 P P T +PAP + TP T P AP ++P P Sbjct: 632 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 691 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILR-KKPATDGMAVR 683 T P S PA TT T + AP P P+ + P T Sbjct: 692 LAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750 Query: 684 KTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQ 743 T P P ++A + +TS P P K + P T + Sbjct: 751 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 810 Query: 744 PTIA--VPPTAQQPPPTI--------------PTMIAAASPPSQPAVALSTIPGAVPITP 787 PT + PT + P TI PT A + P +P V + P A P Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT--KP 868 Query: 788 PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 847 +TT A + + + P + E + + + + T + Sbjct: 869 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 928 Query: 848 ALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEK 907 L T+ L P + KK +++ E ET D + +K+ K +K Sbjct: 929 PFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKATTPKPQK 982 Query: 908 RKSPPKEYIDEEGVRYVPVRPRPPIT 933 PK+ + + +P R R P T Sbjct: 983 PTKAPKKPTSTKKPKTMP-RVRKPKT 1007 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 648 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 757 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 758 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 811 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 812 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 870 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 922 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 923 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 982 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 983 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 1042 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 1043 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1102 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1103 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1156 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 107 bits (267), Expect = 6e-23 Identities = 162/815 (19%), Positives = 259/815 (31%), Gaps = 64/815 (7%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 325 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 326 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 436 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 437 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 546 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 596 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 654 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 714 Query: 512 STIRQ-------YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA 564 +T+++ P + + T P +PA Sbjct: 715 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 774 Query: 565 PISTQGIQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSA 620 P + +G P P T +PAP + P +T +PAP ++ P Sbjct: 775 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834 Query: 621 VVLADGATIVANPISNPFS----AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 P + P + + P T T +S + P + P P L P Sbjct: 835 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 894 Query: 677 TDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETV 736 G+ KT +P + + +++ R +P A PK + T + +T Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA-----TTTEKTT 949 Query: 737 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAP 796 ++ T T Q P T + + + TI + P T A P Sbjct: 950 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET--AKP 1007 Query: 797 PPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 831 T +S P P+ K +P +P Sbjct: 1008 KDRAT-----NSKATTPKPQKPTKAPKKPTSTKKP 1037 Score = 90.9 bits (224), Expect = 6e-18 Identities = 191/926 (20%), Positives = 282/926 (30%), Gaps = 169/926 (18%) Query: 42 LSQAPSQIANSGSAGLINPAATVNDESGRDS-EVSAREHMSSSSSLQSREEKQEPVVVRP 100 ++ PS NS ++ + TVN E+ ++ E + +S+ + +E + Sbjct: 258 INPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 315 Query: 101 YPQVQMLSTHHAVASATPVAVTAP--PAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 + T +A TP A T PA TP P PT P P + P Sbjct: 316 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK------------EPTPTTPKEPASTTP 363 Query: 159 ----PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P+T+ P P + T S P P T + + Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-------------------- 403 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 P P P+ A + TT PT+ Sbjct: 404 ----PAPTT-------PKEPAPTTTKEPAPTTTKSAPTTP-------------------- 432 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 P TT P + T + P TT A + PT + P+A ++ Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KK 489 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 PA T P PA TPK+ P T P T P+ TT Sbjct: 490 PAP--------TTPKEPAPTTPKE---------------PAPTTTKEPSPTTPKEPAPTT 526 Query: 395 AGSVSHT---QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPA 451 S T APT+T T P S TT+ P A P++ T+P+ PA Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPS----PTTTKEP-APTTPKEPAPTTPK----KPA 577 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 + P P P + + P P PT P P TP T Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA------PTTPKETAPTTPKKLTPTTPE- 630 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 + P + + P P +L +PAP + + Sbjct: 631 ---KLAPTTPEKP---------------APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672 Query: 572 QP----APIGTPGIQPAPLGTQGIHSATPINTQGLQP---APMGTQQPQPEGKTSAVVLA 624 P P T +PAP + TP T P AP ++P P Sbjct: 673 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 732 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILR-KKPATDGMAVR 683 T P S PA TT T + AP P P+ + P T Sbjct: 733 LAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791 Query: 684 KTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQ 743 T P P ++A + +TS P P K + P T + Sbjct: 792 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 851 Query: 744 PTIA--VPPTAQQPPPTI--------------PTMIAAASPPSQPAVALSTIPGAVPITP 787 PT + PT + P TI PT A + P +P V + P A P Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT--KP 909 Query: 788 PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 847 +TT A + + + P + E + + + + T + Sbjct: 910 EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 969 Query: 848 ALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEK 907 L T+ L P + KK +++ E ET D + +K+ K +K Sbjct: 970 PFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKATTPKPQK 1023 Query: 908 RKSPPKEYIDEEGVRYVPVRPRPPIT 933 PK+ + + +P R R P T Sbjct: 1024 PTKAPKKPTSTKKPKTMP-RVRKPKT 1048 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 689 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 798 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 799 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 852 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 853 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 911 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 963 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 964 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 1023 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 1024 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 1083 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 1084 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1143 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1144 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1197 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 102 bits (253), Expect = 3e-21 Identities = 223/936 (23%), Positives = 325/936 (34%), Gaps = 153/936 (16%) Query: 35 LGAPSTGLSQAPSQIANSGSAGLINPAATVNDE-SGRDSEVSAREHMSSSSSLQSREEKQ 93 LG P T S A S +GSA TV E G + + A +S++L + Sbjct: 10956 LGEPETTPSMATSHGTEAGSA-----VPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSP 11010 Query: 94 EPVVVRPYPQVQMLSTHHAVASAT-PVAVTAPPAHLTPAVPLSFSEG-------LMKPPP 145 P M ++H A AS+T P P +T V S ++ P Sbjct: 11011 GEPETTP----SMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGE 11066 Query: 146 KPTMPSRPIAPAPPSTLSLP-----PKVPGQVTVTMESSIPQASA-IPVATISGQQGHPS 199 T PS + ++ ++P P V G VT + SS S IP+ T+S + P Sbjct: 11067 LETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSE--PE 11124 Query: 200 NLHHIMTTN--VQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPN 257 + T++ S + + +P P G + V SS VT+ PT + + Sbjct: 11125 TTPSMATSHGVEASSAVLTVSPEVP----------GMVTSLVTSSRAVTSTTIPTLTISS 11174 Query: 258 --AATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSAT-------------RAQSPV 302 T V H + I + P + S + V + V+++ +Q Sbjct: 11175 DEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPET 11234 Query: 303 ITTTAAH-ATDSALSRPTLSIQH-PPSAAIS-IQRPAQSRDVTTRIT-------LPSHPA 352 I + AH T+++ PTL++ P IS + PA+S R T L + P+ Sbjct: 11235 IDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPS 11294 Query: 353 LGTPKQQLHTMAQKTIFSTGTP-----VAAATVAPILAT-NTIP-----SATTAGSVSHT 401 T + + A T S G P + ++ I AT T+P S TA V+H Sbjct: 11295 TVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHP 11354 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 A TST V T P++S H+ TT +I + + + PD P +S + SG Sbjct: 11355 -AVTSTTVPRTTPNYS-HSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSG 11412 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521 S + T S P F + T+ SA P PVS Sbjct: 11413 TDTSIT-IPTLTLSSGEPETTTSFITYSETHTSSAIPTL-----------------PVSP 11454 Query: 522 QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI 581 A + G ST P T IQ I PA +T P TP Sbjct: 11455 GASKMLTSLVISSGTDSTTTF-PTLTETPYEPETTAIQLIHPAETNTM----VPRTTPKF 11509 Query: 582 QPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGA-TIVANPISNPFSA 640 + T + T + T P +++V + G T P + Sbjct: 11510 SHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPY 11569 Query: 641 APAATTVVQTHSQSAST-------NAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPD 693 P T TH ST N +GS PS++ V T IPP P Sbjct: 11570 EPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPG 11629 Query: 694 VASPRVESSMRSTS-------GSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPT- 745 V + +V SS TS SP S H T TV + TV + D Sbjct: 11630 VVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMAS 11689 Query: 746 -IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVT--- 801 + PP P + + +SP + P +A T P + +TTI+ P VT Sbjct: 11690 WVTHPPQTSTPVSRTTSSFSHSSPDATPVMA--TSPRTEASSAVLTTISPGAPEMVTSQI 11747 Query: 802 --VGGSLSSVL-----GPPVPEI-----------------------KVKEEVEPMDIMRP 831 G + S+ + P +PE +V E + I Sbjct: 11748 TSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPG 11807 Query: 832 VSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 867 L T T S LL S DL P ASP Sbjct: 11808 AETSTALPTQTTSSLFTLLVTGTS--RVDLSPTASP 11841 Score = 81.6 bits (200), Expect = 4e-15 Identities = 182/813 (22%), Positives = 306/813 (37%), Gaps = 114/813 (14%) Query: 60 PAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPV 119 P+ + E+ S +S L S + +P V S H + A+A+ V Sbjct: 11293 PSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPE-SPHESEATASWV 11351 Query: 120 AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPS--TLSLPPKVPGQVTVTME 177 A + P ++S +P P++ + P A A T+++ P VP VT + Sbjct: 11352 THPAVTSTTVPRTTPNYSHS--EPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVT 11409 Query: 178 SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAA 237 SS S I + T++ G P +T + + S P P+ GAS + + Sbjct: 11410 SSGTDTS-ITIPTLTLSSGEPETTTSFITYSETHT--SSAIPTLPVSPGASKMLTSLVIS 11466 Query: 238 AVMSSSKVTTVLRPTSQLPNAATAQ---PAVQHII---------HQPIQSRPPVTTSNAI 285 + S+ L T P Q PA + + H + PV ++ Sbjct: 11467 SGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPG 11526 Query: 286 PPA--VVATVSATRAQSPVITTTA-AHATDSALSRPTLSIQ--HPPSAAISIQRPAQSRD 340 P A V+T + + S ++T+ + TD++ + PTLS P + A + PA++ Sbjct: 11527 PEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAET-S 11585 Query: 341 VTTRITLP--SH------PAL----------GTPKQQLHTMAQKTIFS--TGTPVAAATV 380 T T+P SH P++ G P + + S T + +T Sbjct: 11586 TTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTA 11645 Query: 381 APILATNTIPSATTAGSVSHTQAPTS-TIVTMTVPSH-----SSHATAVTTSNIPVAKVV 434 P L + TTA S +H T T+ TVPS +S T ++ PV++ Sbjct: 11646 IPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTT 11705 Query: 435 PQQITHTSPRIQPDYPA----ERSSLIPISGHRASPNPVAME-TRSDNRPSVPVQFQYFL 489 +H+SP P E SS + + +P V + T S S V Sbjct: 11706 -SSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHS 11764 Query: 490 PTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMT 549 P P + L+ H T + + +P ++ +++T + G ++ + P Q T Sbjct: 11765 PGMPETTALLSTHPRTETSKTFPASTVFPQVSET-TASLTIRPGAETSTAL---PTQ--T 11818 Query: 550 VDASHARHIQGIQPAPISTQGIQPAPIGTPGI--QPAPLGTQ-GIHSATPINTQGLQPAP 606 + + G T + +P +PG+ + APL T G ++T I T L Sbjct: 11819 TSSLFTLLVTG-------TSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGL 11871 Query: 607 MGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSP 666 + T +SA T+ +P + S+A T QT + + +P+ S Sbjct: 11872 LETTGLLATS-SSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVG 11930 Query: 667 RPSILRKKPATDGMAVRKTLIP---PQPPDVA------------SPRVESSMRSTSGSPR 711 P R T TLIP P PP + + VE++ +T+GS Sbjct: 11931 PPEFSRTVTGTT-----MTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSS- 11984 Query: 712 PAGAKPKSEIHV---SMATPVTV-SMETVSNQN-------NDQPTIAVPP-------TAQ 753 P AK + + S+ TP+T M T+++++ N + I+ T Sbjct: 11985 PTVAKTTTTFNTLAGSLFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPA 12044 Query: 754 QPPPTIPTMIAAASPPSQPAVALSTIPGAVPIT 786 P T S S P+ +T+P VP T Sbjct: 12045 TSTPVTSTFSPGISTSSIPSSTAATVPFMVPFT 12077 Score = 80.5 bits (197), Expect = 8e-15 Identities = 181/855 (21%), Positives = 303/855 (35%), Gaps = 106/855 (12%) Query: 42 LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPY 101 +S P+ + GL+ T SG SE SA +++ +SS + E + V P Sbjct: 11192 ISAIPTLAVSPTVQGLVTSLVT---SSG--SETSAFSNLTVASS---QPETIDSWVAHPG 11243 Query: 102 PQVQMLSTHHAVASATP---VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 + + V++ P +++ PA + +P + S TMPS +P Sbjct: 11244 TEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSR--FSHSELDTMPSTVTSPEA 11301 Query: 159 PST----LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 S+ ++ P +PG +T + SS SA + + V + + Sbjct: 11302 ESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTV 11361 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ------------ 262 P H P A + ++S T+ + +P+ T+Q Sbjct: 11362 PRTTPNYS-HSEPDTTPSIATSPGAEATSDFPTIT-VSPDVPDMVTSQVTSSGTDTSITI 11419 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA-AHATDSALSRPTLS 321 P + +P + +T S + + T+ + S ++T+ + TDS + PTL+ Sbjct: 11420 PTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLT 11479 Query: 322 IQ--HPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT 379 P + AI + PA++ + R T PK H+ + T+ Sbjct: 11480 ETPYEPETTAIQLIHPAETNTMVPRTT---------PKFS-HSKSDTTL----------- 11518 Query: 380 VAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQIT 439 P+ T+ P A++A S + S +VT VPS + T++ P P + Sbjct: 11519 --PVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTD----TSTTFPTLSETPYEPE 11572 Query: 440 HTSPRIQPDYPAERSSL----IPISGHRASPNPVAMETRS--DNRPSVPVQFQYFLPTYP 493 T+ + +PAE S+ IP HR S +M T D R VP T P Sbjct: 11573 TTATWLT--HPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTT------TIP 11624 Query: 494 PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDAS 553 PS + T +S+ T P +P T +S H TV Sbjct: 11625 PSIPGVVTSQVT--SSATDTSTAIPTLTPSPGEPETT-----ASSATHPGTQTGFTVPI- 11676 Query: 554 HARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG----LQPAPMGT 609 R + +P +++ P TP + + ATP+ A + T Sbjct: 11677 --RTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTT 11734 Query: 610 QQP-QPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQS-ASTNAPAQGSSPR 667 P PE TS + + AT P P T ++ TH ++ S PA P+ Sbjct: 11735 ISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQ 11794 Query: 668 PSILRKKPATDGMAVRKTLIPPQPPD-------VASPRVESSMRSTSG---SPRPAGAKP 717 S A T +P Q + RV+ S ++ G P P Sbjct: 11795 VSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHP 11854 Query: 718 KSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALS 777 +E + T T+S+ + + + + T+ ++ S S Sbjct: 11855 GTETSTMIPTS-TLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQ 11913 Query: 778 TIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLG---PPVPEIKVKEEVEPMDIMRPVSA 834 T+ T P T P S TV G+ +++ P P+ E V P I+R Sbjct: 11914 TVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMV 11973 Query: 835 -VPPLATNTVSPSLA 848 LAT SP++A Sbjct: 11974 EATNLATTGSSPTVA 11988 Score = 75.1 bits (183), Expect = 3e-13 Identities = 189/912 (20%), Positives = 326/912 (35%), Gaps = 150/912 (16%) Query: 26 EMSSQQFPRLGAP-STGLSQAPSQIANSGS---AGLINPAATVNDESGRDSEVSAREHMS 81 E +S LGA ST L + + N S A L++ + + +VS+ E + Sbjct: 10536 ETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDT 10595 Query: 82 SSSSLQSREEKQEPVVVRPYPQ--------VQMLSTHHAVASATPVAVTAPPAHLTPAVP 133 ++S + E P V + P V +T H ++ + P+ L P Sbjct: 10596 TASWVIHPAETI-PTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTP 10654 Query: 134 LSFSEGLMKPPPKPTMPSRP----------IAPAPPSTLSLPPKVPG--------QVTVT 175 L G PT+ P PA S+ ++P +P ++ Sbjct: 10655 LVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSS-TIPRTIPNFSHHESDATPSIA 10713 Query: 176 MESSIPQASAIPVATIS-GQQGHPSNLHHIMTTNVQMSI-IRSNAPGPPLHIGA------ 227 +SAIP+ T+S G + ++ T+ M+I + +PG P I + Sbjct: 10714 TSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPE 10773 Query: 228 ----SHLPRGAAAAAV--MSSSKVTTVLRPTSQLPNAATAQPA-----VQHIIHQPIQSR 276 S +P + AV + +S VT++ TS A T P V + H Sbjct: 10774 AQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTH------ 10827 Query: 277 PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHP----------- 325 P TS +P + +P +TT+ + SA+ PT+S + P Sbjct: 10828 -PAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSR 10886 Query: 326 -------PSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA 378 P +S P + + T + A+ TP T T + + Sbjct: 10887 AVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTS 10946 Query: 379 TVAPILA-----TNTIPS-ATTAGSVSHTQAPT-STIVTMTVPSHSSHATAVTTSNIPVA 431 T PIL T PS AT+ G+ + + PT V V S + + AVT++ +P Sbjct: 10947 TTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTL 11006 Query: 432 KVVP--------------QQITHTSPRIQPDYPAERSSLIPISGHRASP-------NPVA 470 + P + + T P + P+ P +SL+ S S +P Sbjct: 11007 TLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGE 11066 Query: 471 METRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSS-----VSTIRQYPVSAQAPN 525 +ET S + +PT P+ P + TP+ +S +TI +S+ P Sbjct: 11067 LETTPSMATSHGAEASSAVPT--PTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPE 11124 Query: 526 SAITAQTGVGVAS-----TVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQP------- 573 + + T GV + TV ++T + +R + ++ +P Sbjct: 11125 TTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLV 11184 Query: 574 --------APIGTPGIQPAPLG-TQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLA 624 + I T + P G + +++ T + + QP+ A Sbjct: 11185 THSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGT 11244 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPAT------D 678 + +++V P + P + TH +S+ P S S L P+T + Sbjct: 11245 EASSVV--PTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAE 11302 Query: 679 GMAVRKTLIPPQPPDVASPRVESSMRSTSGS-PRPAGAKPKSEIHVSMATPVTVSMETV- 736 + T I P P V + V SS R S + P + +SE S T V+ TV Sbjct: 11303 SSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTVP 11362 Query: 737 -------SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPI 789 ++ + P+IA P A + PT+ + P +++ IT P Sbjct: 11363 RTTPNYSHSEPDTTPSIATSPGA-EATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPT 11421 Query: 790 TTIAAAPPPSVT 801 T+++ P + T Sbjct: 11422 LTLSSGEPETTT 11433 Score = 66.6 bits (161), Expect = 1e-10 Identities = 150/813 (18%), Positives = 298/813 (36%), Gaps = 100/813 (12%) Query: 135 SFSEGLMKPPPKPTMPSRPIAPAPPSTL-SLPPKVPGQVTVTMESSIPQASAIPVATISG 193 SFS LM P P M S P++ P T+ + P + +T ++ + P T S Sbjct: 6800 SFSSSLM---PSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSS 6856 Query: 194 QQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTS 253 S H I+TT+ + I + P S+S T + TS Sbjct: 6857 PPNLSSTSHEILTTDEDTTAIEAMHP---------------------STSTAATNVETTS 6895 Query: 254 QLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDS 313 + ++ A + ++ P+ T++ + V+T + +++ I + ++ Sbjct: 6896 SGHGSQSSVLADS----EKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTP 6951 Query: 314 ALSRPTLSIQHPPSAAISI---------QRPAQSRDVTT--RITLPSHPALGTPKQQLHT 362 L ++S S SI +VT+ R ++P P+ T ++ T Sbjct: 6952 GLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPG-PSQSTVLPEIST 7010 Query: 363 MAQKTIFSTGTPVAAATVAPILATNTIPSATTA-------GSVSHTQAPTSTIVTMTVPS 415 +F++ T +A + + T T PS +T+ S + +QA T + +T P Sbjct: 7011 RTMTRLFASPTMTESAEMT--IPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFP- 7067 Query: 416 HSSHATAVTTSNIPVAKVVPQQITHTS--PRI----QPDYPAERSSLIPISGHRASPNPV 469 HS T ++ ++ + + S P + P SS +P++ S +P+ Sbjct: 7068 HSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVT---ISSSPL 7124 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT----------------YTPITSSVST 513 + + + P + P S+ P +HT P T++ ++ Sbjct: 7125 PVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAAS 7184 Query: 514 IRQYPVSA-QAPNSAITAQTGVGVASTVHLNPMQ---LMTVDASHARHIQGIQPAPISTQ 569 + P S ++P+SA+ S + + Q + + H IQ IS+ Sbjct: 7185 NVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSL 7244 Query: 570 GIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATI 629 + G+ + + T + S I + + +TS A+ + Sbjct: 7245 SPKLRETGSSVETSSAIETSAVLSEVSIGA----TTEISRTEVTSSSRTSISGSAESTML 7300 Query: 630 VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP 689 + P + + ++ + T GS+ + T + + + + Sbjct: 7301 PEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQ 7360 Query: 690 QPPDVASPRVESSMRSTSGSPRPAG------AKPKSEIHVS-MATPVTVSMETVSNQNND 742 + P + S R PRP+ + P S++ +S M +P VS ++ ++ Sbjct: 7361 RLPHSEITTLVS--RGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSS 7418 Query: 743 QPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPP---- 798 ++ T Q T + A+A P + +LS+ + T +TT P Sbjct: 7419 SASVTSLLTPGQ-VKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNT 7477 Query: 799 SVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPT 858 +VT G+ SS P + E + M +S + + +T++P+L+ S P Sbjct: 7478 AVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPA 7537 Query: 859 SDLPPGASPRKKPRKQQHVISTEEGDMMETNST 891 S L R+ ++ ++TE ++ ST Sbjct: 7538 SSLT--TRLRETSTSEETSLATEANTVLSKVST 7568 Score = 64.7 bits (156), Expect = 5e-10 Identities = 198/938 (21%), Positives = 333/938 (35%), Gaps = 161/938 (17%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDE--SGRDSEVSAREHMSSSSSLQSREEKQEP 95 P++ L+ + ++S +TV E SG +EVS E +SS + S ++ Sbjct: 8410 PTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTI 8469 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEG-LMKPPPKPTMPSRPI 154 + LST + + A+T + P + SEG L T S Sbjct: 8470 SPDISTEAITRLSTSPIMTESAESAIT-----IETGSPGATSEGTLTLDTSTTTFWSGTH 8524 Query: 155 APAPPS-----TLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNV 209 + A P +L + PG V S+ +AS++ S P+ MT+ Sbjct: 8525 STASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSV-----SSSLSSPA-----MTSTS 8574 Query: 210 QMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP-----TSQLPNAATAQPA 264 S + P I +S P A + K T +LR TS PN ++ Sbjct: 8575 FFSTL-------PESISSS--PHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAE 8625 Query: 265 V---------QHIIHQPIQSRPPVTTSNAI-----PPAVVATVSATRAQSPVITTTAAHA 310 + + IH P + P V I P +V+A + T+ SP+ TT+ Sbjct: 8626 ILATSEVTKDREKIH-PSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGN 8684 Query: 311 TDSALSRPTL---SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT 367 T + S P + P S+ S R + T+ T S G P +++ Sbjct: 8685 TSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTE 8744 Query: 368 IFS---TGTP-VAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV 423 S T TP A +T++P ++T TI + T T+ MT+ + H+ A Sbjct: 8745 ALSLGRTSTPGPAQSTISPEISTETITRIS-------TPLTTTGSAEMTITPKTGHSGAS 8797 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 + + TS R +P S+ S H P++ + PS P Sbjct: 8798 SQGTFTL---------DTSSR--ASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPS 8846 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 + T PPS + +++ S Y +++ +S+ T + Sbjct: 8847 VEK----TSPPS-------SLVSLSAVTSPSPLYSTPSESSHSSPLRVTSL-------FT 8888 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQ 603 P+ + T D ++P S + + A + T+ I + NT Q Sbjct: 8889 PVMMKTTDMLDT----SLEPVTTSPPSMNITSDESLATSKATMETEAIQLSE--NTAVTQ 8942 Query: 604 PAPMGTQQ---------PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQS 654 + +Q P+P TS VV + + + + PA++ + + +S Sbjct: 8943 MGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVS------TTIPASSEITRIEMES 8996 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSM---RSTSGSPR 711 ST P +PR + ++ + A + + +P + + S +E SM S+S P Sbjct: 8997 TSTLTP----TPRETSTSQEIHS---ATKPSTVPYKA--LTSATIEDSMTQVMSSSRGPS 9047 Query: 712 PAGAKPKSEIHVSMATPVTVS-METVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAAS--- 767 P + +I + T ++ S ++T S + P + T+ T S Sbjct: 9048 PDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTH 9107 Query: 768 -------PPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVK 820 SQ +S PG VP PSV S S L PV Sbjct: 9108 STASQGFSHSQMTALMSRTPGDVP---------WLSHPSVEEASSASFSLSSPV------ 9152 Query: 821 EEVEPMDIMRPVSAVPPLATNTVS-PSLALLANNLSMPTSDLPPGASPRKKPRKQQHVIS 879 M PVS+ P + ++ S P +LL + L T L + P S Sbjct: 9153 -----MTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTS 9207 Query: 880 TEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYID 917 E + E +TD EK +++ +SP D Sbjct: 9208 AEILAITEV-TTDTEKLEMTNVVTSGYTHESPSSVLAD 9244 Score = 63.9 bits (154), Expect = 8e-10 Identities = 199/994 (20%), Positives = 354/994 (35%), Gaps = 149/994 (14%) Query: 6 HPQAGEIEAGGAGGGRR---LQVEMSSQQFPRLG-------APSTGLSQAPSQIANSGSA 55 H + + + GAG R L VE +S +L +P + A S +++ Sbjct: 7364 HSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVT 7423 Query: 56 GLINPAATVNDE---SGRDSEVSAREHMSSSSS--LQSREEKQEPVVVRPYPQVQMLSTH 110 L+ P E + + E S+ +SS+S L + E + + P+ + Sbjct: 7424 SLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVG 7483 Query: 111 HAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMP-----SRPIAPAPPSTLSLP 165 + + + P + T A + +M T+ +R I P S+L+ Sbjct: 7484 TSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTR 7543 Query: 166 PKVPGQVTVTMESSIP-QASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLH 224 + + + + E+S+ +A+ + +G S I + MS + + Sbjct: 7544 LR---ETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDIS 7600 Query: 225 IGASHLPRGAAAAAVMSSSKVT---------TVLRPTSQLPNAATAQPAVQHIIHQPIQS 275 IG +PR +A++ + S+K+T + L T L A T H I Sbjct: 7601 IGT--IPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFP 7658 Query: 276 RPPVTTS-----------------NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP 318 P +TTS PP+ ++ A + PV TT AH S L Sbjct: 7659 HPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVT 7718 Query: 319 TLSIQHPPSAAISIQRPAQ-SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAA 377 +L P + + + ++ ++ SH L T K HT A +TG Sbjct: 7719 SLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTG----- 7773 Query: 378 ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQ 437 TN +++ S S A +S + T + +S T+ T + + ++ + Sbjct: 7774 -------GTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTS-TPAFLETRRIQTEL 7825 Query: 438 ITHTSPRIQPDYPAERSSLIPISGHRAS------PNPVAMETRSDNRPSVPVQFQYFLPT 491 + +P ++ +E +S SG + S P E ++ S+P Sbjct: 7826 ASSLTPGLRESSGSEGTS----SGTKMSTVLSKVPTGATTEISKEDVTSIP--------- 7872 Query: 492 YPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVD 551 P+ ++ T S ST SA+ + T+ G T L+ ++ Sbjct: 7873 -GPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLT 7931 Query: 552 ASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 +H+ QG + +ST ++ P + P PL + P + PA T Sbjct: 7932 MTHSTISQGFSHSQMSTL-MRRGPEDVSWMSP-PL----LEKTRPSFSLMSSPA---TTS 7982 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671 P P T L + + P+++ ++ A TT + S TN+PA SS IL Sbjct: 7983 PSPVSST----LPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEIL 8038 Query: 672 RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTV 731 A + + +S R + + TS S + + ++ S T V Sbjct: 8039 ---------ATSEVTTDTEKTHPSSNRTVTDV-GTSSSGHESTSFVLADSQTSKVTSPMV 8088 Query: 732 SMETVSNQNNDQPTIAVPPTAQ-QPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT 790 T+ + + T T++ Q PT + S +L+T V P Sbjct: 8089 ITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTG 8148 Query: 791 TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALL 850 A VT S +S+ G ++ V E I R L T+++ A Sbjct: 8149 ATAEVSRTEVT-SSSRTSISG--FAQLTVSPETSTETITR-------LPTSSIMTESA-- 8196 Query: 851 ANNLSMPTSDLPPGASP-----------------------RKKPRKQQHVISTEEGDMM- 886 + + T PPG++P R + ++S GDM+ Sbjct: 8197 --EMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLW 8254 Query: 887 ETNSTDDEKSTAKSLL-VKAEKRKSPPKEYIDEE 919 + S+ +E S+A SLL + A SP + E+ Sbjct: 8255 PSQSSVEETSSASSLLSLPATTSPSPVSSTLVED 8288 Score = 63.5 bits (153), Expect = 1e-09 Identities = 200/924 (21%), Positives = 325/924 (35%), Gaps = 147/924 (15%) Query: 52 SGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQ------SREEKQEPVVVRPYPQVQ 105 S S L++ A+ + D+ S S H ++SS+ S + K V+ Sbjct: 721 STSIPLLSSASVLEDKVSATSTFS---HHKATSSITTGTPEISTKTKPSSAVLSSMTLSN 777 Query: 106 MLSTHHAVASAT-PVAVTAPPAHLTPAVPLSFS---EGLMKPPPKPTMPSRPIAPAPPST 161 ++ V +AT P+ +P T L+ S E P PT + PST Sbjct: 778 AATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPST 837 Query: 162 LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPS-NLHHIMTTNVQMSIIRSNAPG 220 LSLP V G V T SS P + + +PS + + V+ ++ ++ P Sbjct: 838 LSLP-SVSG-VKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPT 895 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLP---NAATAQPAVQHIIHQPIQSRP 277 P + +A SSS + + LR TS + +A P + H+ S+ Sbjct: 896 PVFPT----MDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQT 951 Query: 278 PVTTSN--AIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRP 335 T N A P + ++ R ++ + + T +T + T+ + S P Sbjct: 952 NRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTS-------P 1004 Query: 336 AQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP-ILATNTIPSATT 394 A S T I PS L T + + + ST P+ + L T+ +P TT Sbjct: 1005 ATSSMEATSIREPSTTILTT--ETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTT 1062 Query: 395 AGS---VSHTQAPTSTIVTMTVPSHSSHATAVTTSN----------------------IP 429 A S + T A S ++++ PS S A +T IP Sbjct: 1063 ASSETSMDFTMAKESVSMSVS-PSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIP 1121 Query: 430 ---VAKVVPQQITHTSPRIQPDYPAERSSLIPI-SGHRASPNPVAMETRSDNRPSVPVQF 485 + + Q+T T P PD + RS+ + I S +SP P T S + V Sbjct: 1122 RDGTSSALTPQMTATHPP-SPDPGSARSTWLGILSSSPSSPTPKV--TMSSTFSTQRVTT 1178 Query: 486 QYFLPTYPPSAYPL----AAHTYTP--ITSSVSTIRQYPVSAQAPNSAITAQTGVGVAST 539 + T S + + + + TP I +S + + V P+ A + + G T Sbjct: 1179 SMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPT 1238 Query: 540 VHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT 599 + P T H P+ I + A + PG PL I + ++T Sbjct: 1239 LSTYPESTNTPSIHLGAHASSESPSTIK---LTMASVVKPGSY-TPLTFPSIETHIHVST 1294 Query: 600 ------QGLQP---APMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQT 650 G P AP T T+ + D + +S P S TT + Sbjct: 1295 ARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTT--EN 1352 Query: 651 HSQSASTNAPAQGSSPRPSILRK--KPATDGMAVRKT----------------------- 685 H ++ S A SP+ S PAT + T Sbjct: 1353 HPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQS 1412 Query: 686 ------LIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSM-ETVSN 738 ++ P P + S +E + G P ++ I + MAT ++ S+ E +++ Sbjct: 1413 APGPVSVVIPTSPTIGSSTLELTS-DVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMAS 1471 Query: 739 QNND--QPTIAVPPTAQQPPPTIPTMIAAASPPSQPAV------ALSTIPG--------- 781 + D P+ + A PP + P+ + S A+ L G Sbjct: 1472 TDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGD 1531 Query: 782 --AVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLA 839 VPITP TT + S +LS+ + P +K++ P SA P Sbjct: 1532 LTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTS-----IPASASPSHL 1586 Query: 840 TNTVSPSLALLANNLSMPTSDLPP 863 T V P L + S T+ P Sbjct: 1587 TE-VYPELGTQGRSSSEATTFWKP 1609 Score = 63.5 bits (153), Expect = 1e-09 Identities = 168/775 (21%), Positives = 270/775 (34%), Gaps = 120/775 (15%) Query: 180 IPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAP------GP---PLHIGASHL 230 +P A I T+ + TT V +I S +P GP L A L Sbjct: 10267 LPSAETISTGTVMPSLSEA--MTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESL 10324 Query: 231 PRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVV 290 P ++ SSS TT T + T+ A + + + + T + + + Sbjct: 10325 P--SSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTL 10382 Query: 291 ATVS--ATRAQSPVITTTAAHATD-----SALSRPTLSIQHPPSAAI-----SIQRPAQS 338 T S + SP++ T + + SA P+LS + + I I A Sbjct: 10383 DTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAH 10442 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 R + P + LHT K + +T T L T T TT+ + Sbjct: 10443 RGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTA---------LKTTTTALKTTSRAT 10493 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 T T T+ T+T P ++S + +A +P ++ T+P + PD P SSL Sbjct: 10494 LTTSVYTPTLGTLT-PLNAS---------MQMASTIPTEMMITTPYVFPDVPETTSSLAT 10543 Query: 459 ISG---------------HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPS-------- 495 G +R S ++ +RS S +Q + P + Sbjct: 10544 SLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHP 10603 Query: 496 ---------AYPLAAHTYTPITSSVSTIRQYPVSAQAPNS-------AITAQTGVGVAST 539 P H+ SS +T VS+ P + A+T + T Sbjct: 10604 AETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDT 10663 Query: 540 VHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAP-------IGTPGIQPAPLGTQGIH 592 P + + R PA S+ + P TP I +P G + Sbjct: 10664 STTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSP-GAE-TS 10721 Query: 593 SATPINTQGLQPAPMGTQQPQPEG-----KTSAVVLADG-----ATIVANPISNPFSAAP 642 SA PI T + T Q G + L+ G A++V +P + SA P Sbjct: 10722 SAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIP 10781 Query: 643 AAT--TVVQTHSQSASTNAPAQGSSPRPSILRK--KPATD-GMAVRKTLIPPQPPDVASP 697 +T V S T+ A+ S+ ++ +PAT + P P S Sbjct: 10782 TSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSI 10841 Query: 698 RVESSMRSTSGSPRPAGAKPKSEI---HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 754 S +T GA+ S + VS P V+ S++ TI + + Sbjct: 10842 FFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPG 10901 Query: 755 PPPTIPTMIAAASPPSQPAVALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLGP 812 P T P+M + + A+ T+ VP +T +T+ A ++ + L+ LG Sbjct: 10902 EPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPI---LTFSLGE 10958 Query: 813 P--VPEIKVKEEVEPMDIMRPV-SAVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 P P + E + V VP + T+ V+ S A+ + L PT L PG Sbjct: 10959 PETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTL--PTLTLSPG 11011 Score = 58.2 bits (139), Expect = 4e-08 Identities = 177/839 (21%), Positives = 291/839 (34%), Gaps = 127/839 (15%) Query: 78 EHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS-- 135 E SSSSSL S P V PQ S+ + TP V P LS Sbjct: 10016 EKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPN 10075 Query: 136 --------FSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESS---IPQAS 184 + + + PS +A T S ++ V++ E S P + Sbjct: 10076 LSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGT 10135 Query: 185 AIPVATISGQQGHPSNLH----------HIMT----TNVQM---SIIRSNAPGPPLHIGA 227 +A S P+N H+ + TN+ + S+ +N P P G+ Sbjct: 10136 PSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSP---GS 10192 Query: 228 SHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP- 286 +HL + + S+ + P SQ + I P + P +T S I Sbjct: 10193 THLLQSSKTDFTSSAKTSSPDWPPASQYTE-------IPVDIITPFNASPSITESTGITS 10245 Query: 287 -PAVVATVSATRAQSPVIT--TTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTT 343 P T+S T + + T +A + P+LS A S R ++ Sbjct: 10246 FPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLS-----EAMTSFATTGVPRAISG 10300 Query: 344 RITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT-------VAPILATNTIPSA---- 392 + S G L T+A+ ST P +++T P L T SA Sbjct: 10301 SGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYR 10360 Query: 393 --TTAGSVSHTQ----APTSTIVTMTVPSHSSHATAVTT--------SNIPVAKVVPQ-- 436 T+ G+ S T ST+ T + P +S + + T + A VP Sbjct: 10361 VDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLS 10420 Query: 437 -QITHTSPRIQ-----PDYPAERSSLIPISGHRASPNPVA-----------METRSDNRP 479 ++T T ++ P+ A R ++ P+ G + S +P + MET + Sbjct: 10421 TRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALK 10480 Query: 480 SVPVQFQ-YFLPTYPPSAYPLAAHTYTPITSSVSTIRQYP---------VSAQAPNSAIT 529 + + T S Y T TP+ +S+ P V P + + Sbjct: 10481 TTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSS 10540 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPI----GTPGIQPAP 585 T +G ++ L P +V + + +S G + +P+ +P Sbjct: 10541 LATSLGAETSTAL-PRTTPSVFNRESETTASL----VSRSGAERSPVIQTLDVSSSEPDT 10595 Query: 586 LGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT 645 + IH A I T + T+ AD ++ + IS S A T Sbjct: 10596 TASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISP--SELDALT 10653 Query: 646 TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRS 705 +V ST P SP + R T T IP P+ S + S Sbjct: 10654 PLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSST-IPRTIPNF-SHHESDATPS 10711 Query: 706 TSGSPRPAGAKPKSEIHVSMATPVT---VSMETVSNQNNDQPTIAVPPTAQQPPPTIPTM 762 + SP GA+ S I + +P V+ + S+ + TI + P TI ++ Sbjct: 10712 IATSP---GAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASL 10768 Query: 763 IAAASPPSQPAVALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKV 819 + + A+ STI AV +T +T++AA + T +L++ G P + + Sbjct: 10769 VTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAA---KTSTTNRALTNSPGEPATTVSL 10824 Score = 57.0 bits (136), Expect = 9e-08 Identities = 164/756 (21%), Positives = 258/756 (34%), Gaps = 143/756 (18%) Query: 78 EHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS 137 E SSSSSL P + + S H+ +S PV +V LS + Sbjct: 4154 EETSSSSSLVPIHATTSP------SNILLTSQGHSPSSTPPVT----------SVFLSET 4197 Query: 138 EGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGH 197 GL K + P PP+ S G+ T E+S + Sbjct: 4198 SGLGKTTDMSRISLEPGTSLPPNLSS----TAGEALSTYEASRDTKA------------- 4240 Query: 198 PSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPN 257 +HH T V S+ P H A + +++S + + TS + Sbjct: 4241 ---IHHSADTAVTNMEATSSEYSPI----PGHTKPSKATSPLVTSHIMGDITSSTSVFGS 4293 Query: 258 AATAQPAVQHIIHQPIQSRPP--VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSAL 315 + T + ++Q +Q R V +S V+ VS+ A + V T A ++ +++ Sbjct: 4294 SETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSI 4353 Query: 316 SRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPV 375 S P I + T T PS + T + TI + P Sbjct: 4354 SSPHQFI-------------TSTNTFTDVSTNPSTSLIMTESSGV------TITTQTGPT 4394 Query: 376 AAATVAP-ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVV 434 AAT P +L T+T+P T T + +T S T + + Sbjct: 4395 GAATQGPYLLDTSTMPYLT------------ETPLAVTPDFMQSEKTTLISKG------- 4435 Query: 435 PQQITHTSPR--IQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTY 492 P+ ++ TSP + YP SSL P + P A T S PV L + Sbjct: 4436 PKDVSWTSPPSVAETSYP---SSLTPFL---VTTIPPATSTLQGQHTSSPVSATSVLTSG 4489 Query: 493 PPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT-----------AQTGVGVASTVH 541 + + P+T+S + A +A T A T +G AS+ H Sbjct: 4490 LVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAH 4549 Query: 542 LNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG 601 + T+ S P S+ G A I PG + + + S T + Sbjct: 4550 VLHS---TLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKEN 4606 Query: 602 LQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPA 661 T Q S ++L SN A T ++ S A+ Sbjct: 4607 ------STLQEMNSTTESNIIL-----------SNVSVGAITEATKMEVPSFDATF---- 4645 Query: 662 QGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAG-AKPKSE 720 P P+ K P D +V + + PP S + ++ +SG+ A S Sbjct: 4646 ---IPTPAQSTKFP--DIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTST 4700 Query: 721 IHVSMATPVTVS-----METVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVA 775 + S TP V+ + + NND V +Q PP A+SP SQ V Sbjct: 4701 LETSAGTPSVVTEGFAHSKITTAMNND-----VKDVSQTNPPF---QDEASSPSSQAPVL 4752 Query: 776 LSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLG 811 ++T+P +V TP + ++ S + SL G Sbjct: 4753 VTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAG 4788 Score = 57.0 bits (136), Expect = 9e-08 Identities = 163/816 (19%), Positives = 285/816 (34%), Gaps = 153/816 (18%) Query: 128 LTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIP 187 L + P+ FS T+P+ + +T G + T E + S + Sbjct: 10324 LPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLD 10383 Query: 188 VATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTT 247 ++ G+ L MT +V++ + S P L ++ L R Sbjct: 10384 TSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSL---STRLTR------------TDG 10428 Query: 248 VLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQ 299 ++ +++PN A + ++ P++ P +TS A P + T +A + Sbjct: 10429 IMEHITKIPNEAAHRGTIR-----PVKG-PQTSTSPASPKGLHTGGTKRMETTTTALKTT 10482 Query: 300 SPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRD-VTTRITLPSHP------- 351 + + TT+ +++ PTL P +A++ + + +TT P P Sbjct: 10483 TTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLA 10542 Query: 352 -ALGTPKQQLHTMAQKTIFSTGTPVAAATVA-------PILATNTIPSA---TTAGSVSH 400 +LG ++F+ + A+ V+ P++ T + S+ TTA V H Sbjct: 10543 TSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIH 10602 Query: 401 TQAPTSTI--------------VTMTVPSHSSHATAVTTSNI---------PVAKVVPQQ 437 T+ V+ T SH + ++ +NI P+ + Sbjct: 10603 PAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTD 10662 Query: 438 ITHTSPRIQPD------------YPAERSSLIP-----ISGHRASPNP-VAMETRSDNRP 479 + T P + +PAE SS IP S H + P +A ++ Sbjct: 10663 TSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSS 10722 Query: 480 SVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVAST 539 ++P+ T P A L T +S P +P T + V Sbjct: 10723 AIPIM------TVSPGAEDLVTSQVT--SSGTDRNMTIPTLTLSPGEPKTIASLVTHPEA 10774 Query: 540 VHLNPMQLMTVDASHARHIQG-IQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPIN 598 + + T+ + +R + + T A +PG +PA + H P Sbjct: 10775 QTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPG-EPATTVSLVTH---PAQ 10830 Query: 599 TQGLQPAPMGTQQPQPEGKTSAVVLADGA-TIVANPISNPFSAAPAATTVVQTHSQSA-S 656 T P T ++ + GA + A P + P T + T S++ S Sbjct: 10831 TSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVIS 10890 Query: 657 TNAPAQGSSP-----RPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGS-P 710 T P SP PS+ A+ + P P V + V SS TS + P Sbjct: 10891 TTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIP 10950 Query: 711 RPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPS 770 + + E SMAT + + AVP + P + +++A S Sbjct: 10951 ILTFSLGEPETTPSMAT-----------SHGTEAGSAVPTVLPEVPGMVTSLVA-----S 10994 Query: 771 QPAVALSTIPGAVPITP--PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDI 828 AV +T+P + ++P P TT P + + G SS + PE Sbjct: 10995 SRAVTSTTLP-TLTLSPGEPETT----PSMATSHGAEASSTVPTVSPE------------ 11037 Query: 829 MRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 VP + T+ V+ S + N+ S+PT L PG Sbjct: 11038 ------VPGVVTSLVTSSSGV--NSTSIPTLILSPG 11065 Score = 55.8 bits (133), Expect = 2e-07 Identities = 187/889 (21%), Positives = 302/889 (33%), Gaps = 179/889 (20%) Query: 33 PRLGAPSTGLS-QAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREE 91 P PST S P+ A + P + D G + S +S+LQ Sbjct: 4556 PVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTS-SLTAGRKENSTLQEMNS 4614 Query: 92 KQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 E ++ V A+ AT + V + A P S K P ++ S Sbjct: 4615 TTESNIILSNVSVG------AITEATKMEVPSFDATFIPTPAQS-----TKFPDIFSVAS 4663 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA----TISGQQGHPSNL-----H 202 ++ +PP T+S +T T S S IP+A T+ G PS + H Sbjct: 4664 SRLSNSPPMTIST------HMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAH 4717 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 +TT + + + PP AS P+SQ P T Sbjct: 4718 SKITTAMNNDVKDVSQTNPPFQDEASS---------------------PSSQAPVLVTTL 4756 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSI 322 P+ Q + PV+ S+ + ++V T A D++L T S Sbjct: 4757 PSSVAFTPQWHSTSSPVSMSSVLTSSLVKT---------------AGKVDTSLETVTSS- 4800 Query: 323 QHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP 382 P S + ++ + + TT I +HP++ T + + GT +A Sbjct: 4801 --PQSMSNTLDDISVTSAATTDIE-TTHPSINT-----------VVTNVGTTGSAFESHS 4846 Query: 383 ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA---TAVTTSNIPVAK--VVPQQ 437 ++ PS T+ +V+ T T ++ ++P S T T+S P + + Q+ Sbjct: 4847 TVSAYPEPSKVTSPNVT-TSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQE 4905 Query: 438 ITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY 497 IT ++ +S +P + V +R+D S F P + Sbjct: 4906 ITSST----------ETSTVPYKELTGATTEV---SRTDVTSSSSTSFPG--PDQSTVSL 4950 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 ++ T T +++S P+ ++ IT QTG A++ T+D S+ Sbjct: 4951 DISTETNTRLSTS-------PIMTESAEITITTQTGPHGATS-----QDTFTMDPSNT-- 4996 Query: 558 IQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGK 617 TP GIHSA L + ++ PQ Sbjct: 4997 --------------------TP--------QAGIHSAMTHGFSQLDVTTLMSRIPQDVSW 5028 Query: 618 TSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 TS ++ + F ++PA T T S +ST + SSP S+L T Sbjct: 5029 TSP------PSVDKTSSPSSFLSSPAMT----TPSLISSTLPEDKLSSPMTSLL-----T 5073 Query: 678 DGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVS 737 G+ ++ + V S S S +K EI S+ T ET Sbjct: 5074 SGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTE-----ETNV 5128 Query: 738 NQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPP 797 NN P A P T + + PA + S +P+ T Sbjct: 5129 KANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTS-----MPVHGSSETTNIKRE 5183 Query: 798 PSVTVGGSLSSVLGPPVPEIKVKEEVE-PMDIMRPVSAVPPLATNTVSPSLALLANNLSM 856 P+ L P + E +E P D +S VP VS + ++ +S Sbjct: 5184 PTY--------FLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKIST 5235 Query: 857 PTSD---LPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLL 902 P D +PP + PR I T+ +M T +S + S L Sbjct: 5236 PDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTL 5284 Score = 54.3 bits (129), Expect = 6e-07 Identities = 196/917 (21%), Positives = 324/917 (35%), Gaps = 209/917 (22%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVND-------------------ESGRDSEVSARE 78 PST LS+A S SG +G+ NP++T + E+ +A Sbjct: 2065 PSTSLSEALS----SGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAAST 2120 Query: 79 HMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPA---------HLT 129 + +SS+ E + + M T + S TA P+ LT Sbjct: 2121 LNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLT 2180 Query: 130 PAVPLSFSEGLM--KPPPKPTMPSRPIA--PAPPSTLSLPPK---VPGQVTVTME----- 177 + L SE L+ + P S P+ P + S+P PG TV + Sbjct: 2181 RTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVASDVIDTP 2240 Query: 178 ----SSIPQASAIP-----VATIS---GQQGHP----SNLHHIMTTNVQ------MSIIR 215 SIP S P V TIS + H S+L H +T+ V MS Sbjct: 2241 SDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAM 2300 Query: 216 SNAP---GPPLHIG-----ASHLPRGAAAAAVMSSSKVTTV---------------LRPT 252 S P P + +G S P + S ++ +TV R T Sbjct: 2301 STKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKT 2360 Query: 253 SQLPNAATAQPAVQHIIHQPI-QSRPPVTTSNAIPPAVVATVSAT---------RAQSPV 302 ++LP+ +++ +I+ I S VT + +I P ++ ++A+ R Q P Sbjct: 2361 NELPSDSSSS---SDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPT 2417 Query: 303 ITTTAAHATDSALSR------------------PTLSIQHPPSAAISIQRPAQSRDVTTR 344 TT AT ++S P +I HP + ++ A SR V T Sbjct: 2418 STTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALL--AWSRPVRTF 2475 Query: 345 ITLPSHPALG--TPKQQLHTMAQKTIFSTGTPVAAATVAPILA-TNTIPSATTAGSVSHT 401 T+ S P + T T V + T P + T P+ ++ T Sbjct: 2476 STMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLAST 2535 Query: 402 QAPTS------TIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSS 455 P + + +T S +S A+ +TTS PQ T + + A S Sbjct: 2536 IEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPES 2595 Query: 456 LIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYP----LAAHTYTPITSSV 511 L+ ++ +T ++ V + + PPS +P L+ ++ + Sbjct: 2596 LLVVT--------ETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDT 2647 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 I P++A P S++ A++ P+ + D+ + P +T + Sbjct: 2648 PAI---PLTATEPTSSL--------ATSFDSTPLVTIASDS--------LGTVPETTLTM 2688 Query: 572 QPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA 631 G + S I QG+ +P+ P + + ++A T Sbjct: 2689 SETSNGDALVLKTVSNPD--RSIPGITIQGVTESPL-----HPSSTSPSKIVAPRNTTYE 2741 Query: 632 NPISNPFSAAPAATT---VVQTHSQSASTNAPAQGSS--PRPSILRKKPATDGMAVRKTL 686 I+ S PA TT V S+++ T A S+ R S++ + GMA Sbjct: 2742 GSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMA----- 2796 Query: 687 IPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSM-ATPVTVSMETVSN-----QN 740 SS SGS G K S + ++M VT E +N Q+ Sbjct: 2797 --------------SSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQS 2842 Query: 741 NDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSV 800 I V PT+ + + T ++A+S PS+ +L+T P I T + PS+ Sbjct: 2843 TAPKGIPVKPTSAE--SGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSL 2900 Query: 801 --------TVGGSLSSV 809 T G SL+++ Sbjct: 2901 DTKSASLPTPGQSLNTI 2917 Score = 51.6 bits (122), Expect = 4e-06 Identities = 170/862 (19%), Positives = 304/862 (35%), Gaps = 126/862 (14%) Query: 109 THHAVASATPVAVTAPPAHLTP---AVPLSFSEGLMKPPPKPTMPSRPIAPAP----PST 161 TH A P +V P P + P S PP S +P+P PS Sbjct: 9395 THSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSG 9454 Query: 162 LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP 221 S VP VT S + +A+ + A++ + N++ +T++ ++ ++ Sbjct: 9455 SSHSSPVP--VTSLFTSIMMKATDMLDASLEPETTSAPNMN--ITSDESLAASKATTETE 9510 Query: 222 PLHI----GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP 277 +H+ ASH+ +A + SSS + PT + T+ +++ + Sbjct: 9511 AIHVFENTAASHVETTSATEELYSSSPGFS--EPTKVISPVVTSSSIRDNMVSTTMPGSS 9568 Query: 278 PVT-----TSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +T + +++ P + T ++ S T+T + S + + PS+ SI Sbjct: 9569 GITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSI 9628 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 PAQS T + + + T + + +T T + AT Sbjct: 9629 PGPAQS---TMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLAT------------- 9672 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP-VAKVVPQQITHTSPR-IQPDYP 450 S P T +T +HS+ + ++ S + + P+ ++ TSPR ++ Sbjct: 9673 ------SQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRS 9726 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSS 510 + + +P++ S +PV+ T D+ PS P+ + + + P TSS Sbjct: 9727 SSSLTSLPLT---TSLSPVS-STLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSS 9782 Query: 511 VSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA----PI 566 + V A + +T + +S + ++ T + H H + + I Sbjct: 9783 SPNLSSTSVEIPATSEIMTDTEKIHPSSNTAV--AKVRTSSSVHESHSSVLADSETTITI 9840 Query: 567 STQGIQPAPIGTPGIQPAP-------LGTQGIHSATP--INTQGLQPAPMGTQQPQ---- 613 + GI A T P + T+ S TP T + T+ Sbjct: 9841 PSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYG 9900 Query: 614 -PEGKTSAVVLAD--GATIVANPISNPFSAAPAATTVVQTH-------SQSASTNAPAQG 663 P T+ V + + + + P S+ + +P T V T S+S Q Sbjct: 9901 VPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQK 9960 Query: 664 SSP---RPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE 720 SSP S L T +A + +P PR S +T S P KS Sbjct: 9961 SSPGATAQSTLTLATTTAPLARTHSTVP--------PRFLHSEMTTLMSRSPENPSWKSS 10012 Query: 721 IHVS--------MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQP 772 + V ++ PVT S S P+ + T+ P + T + P + Sbjct: 10013 LFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSL 10072 Query: 773 AVALS----TIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDI 828 + LS I A +T I + +VT G+ SS G + V EP Sbjct: 10073 SPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSS--GHELYS-SVSIHSEPSKA 10129 Query: 829 MRPVSAVPPLATNTVSPSL-------------------ALLANNLSMPTSDLPPGASPRK 869 PV +A ++S S+ N+S+ TS + P +P Sbjct: 10130 TYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSS 10189 Query: 870 KPRKQQHVISTEEGDMMETNST 891 H++ + + D + T Sbjct: 10190 P--GSTHLLQSSKTDFTSSAKT 10209 Score = 48.1 bits (113), Expect = 4e-05 Identities = 177/867 (20%), Positives = 315/867 (36%), Gaps = 121/867 (13%) Query: 115 SATPVAVTAPPA-HLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG--- 170 ++ PV+ T P H TP+ S P M + + +P T S PP + Sbjct: 6812 TSPPVSSTLPKTIHTTPSPMTSLLT------PSLVMTTDTLGTSPEPTTSSPPNLSSTSH 6865 Query: 171 ------QVTVTMESSIPQAS--AIPVATISGQQGHPSNL--------------------H 202 + T +E+ P S A V T S G S++ H Sbjct: 6866 EILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGH 6925 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 ++T++ +S + + L + + S+ + VL S++P TA+ Sbjct: 6926 TTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVL---SEVPTGTTAE 6982 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSI 322 + + S P + S +P T++ A SP +T +A T+ Sbjct: 6983 VSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFA-SPTMTESA---------EMTIPT 7032 Query: 323 QHPPSAAISIQRPAQSRDVTTRITLPSHPALGT--PKQQLHT--------MAQKTIFSTG 372 Q PS + S Q TT+ +H L P ++ T M+ ++ S Sbjct: 7033 QTGPSGSTS-QDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLE 7091 Query: 373 TPVAA-------ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTT 425 P + AT +P ++T+P ++ + T TS+ VT T H+S ++ Sbjct: 7092 NPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSS 7151 Query: 426 ----SNIPVAKVVPQQITHTSPRIQPDYPAERSSL-IPISGHRASPNPVAMETRSDNRPS 480 S+ ++ + T + + P S++ IP SGH + + +A D+ S Sbjct: 7152 PPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALA-----DSETS 7206 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 + T + ++ TP S I++ +S+ +P T + V +S + Sbjct: 7207 KATSPMFITSTQEDTTVAIS----TPHFLETSRIQKESISSLSPKLRETG-SSVETSSAI 7261 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGI--HSATPIN 598 + + L V I + S I + T + P T+ I +PI Sbjct: 7262 ETSAV-LSEVSIGATTEISRTEVTSSSRTSISGSAEST--MLPEISTTRKIIKFPTSPIL 7318 Query: 599 TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTN 658 + + + TQ P + + D +T + I++ + T HS+ + Sbjct: 7319 AESSE-MTIKTQTSPPGSTSESTFTLDTSTTPSLVITH------STMTQRLPHSEITTLV 7371 Query: 659 APAQGSSPRPSIL---RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGA 715 + G PRPS L P + +++ +I P P P S ++ S G Sbjct: 7372 SRGAGDVPRPSSLPVEETSPPSSQLSL-SAMISPSPVSSTLPASSHSSSASVTSLLTPGQ 7430 Query: 716 KPKSEIHVSMATPVTVSMETVSNQNND-QPTIAVPPTAQQPPP---TIPTMIAAAS---- 767 +E+ + A P T S ++S+ + + T V ++ P T T + +S Sbjct: 7431 VKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHE 7490 Query: 768 ------PPSQPAVALSTIPGAVPI--TPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKV 819 P S+ A S + G + I ++T+ A + + +S L + E Sbjct: 7491 SPSSVLPDSETTKATSAM-GTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETST 7549 Query: 820 KEEVE-PMDIMRPVSAVPPLATNTVSPSLALLANNLSM---PTSDLPPGASPRKKPRKQQ 875 EE + +S V AT VS + A+ + SM S + S PR Sbjct: 7550 SEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISA 7609 Query: 876 HVISTEEGDMMETNSTDDEKSTAKSLL 902 + TE M T T +ST +S L Sbjct: 7610 SSVLTESAKMTITTQTGPSESTLESTL 7636 Score = 46.6 bits (109), Expect = 1e-04 Identities = 197/932 (21%), Positives = 316/932 (33%), Gaps = 166/932 (17%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 PST S A S +S + + V G S + ++SS+ L S + Sbjct: 3580 PSTWSSTAAS---DSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRIT 3636 Query: 98 VRPYPQVQMLSTHHAVASATPVAV-TAPPAHLTPAVPLS-FSEGLMKPPPKPTMPSRPIA 155 V V S AV + T + T P+ T + P+S FS P + S Sbjct: 3637 VIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWT 3696 Query: 156 PAPPSTLSLP--------------PKVPGQVTV-----TMESSIPQASAIPVATISGQQG 196 P+ +P P P + T++ ++ + AT S QG Sbjct: 3697 PSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQG 3756 Query: 197 HPSNLHHIMTTNVQMSIIRSNAPGP---PLHIGASHLPRGAAAAAVMSSSKVT-TVLRPT 252 TT ++++ +P P IG H+ AA+ SS VT + PT Sbjct: 3757 --------ATTPQELTLETMISPATSQLPFSIG--HITSAVTPAAMARSSGVTFSRPDPT 3806 Query: 253 SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATD 312 S+ + Q H R TT + IP + + Q TT A AT Sbjct: 3807 SKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATS 3866 Query: 313 SALSRPTLSIQHPP-----------------SAAISIQRPAQSRDVTTRITLPSHPA--- 352 + + S P +++ S+ R + D+ S P+ Sbjct: 3867 DSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKS 3926 Query: 353 ----------LGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQ 402 T K+ +H + T+ +TG T + + +TIP+ + + ++ Sbjct: 3927 SPYERIAPSESTTDKEAIHP-STNTVETTGW----VTSSEHASHSTIPAHSASSKLTSPV 3981 Query: 403 APTST----IVTMTVPSHSSHATAVTTSN----IPVAKVVPQQITHTS------------ 442 TST IV+M+ + A T N I + V P T ++ Sbjct: 3982 VTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGST 4041 Query: 443 -----PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFL--PTYPPS 495 PR + SS R+S +P TR N P++ L T PP Sbjct: 4042 AITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPG 4101 Query: 496 AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHA 555 A L+A T ++ T + + S T G T +P + +S + Sbjct: 4102 ATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSS 4161 Query: 556 RHIQGIQPAP----ISTQGIQPAPIGTPGIQPAPLG-TQGIHSATPINTQGLQPAPMGTQ 610 +P +++QG P+ TP + L T G+ T ++ L+P GT Sbjct: 4162 LVPIHATTSPSNILLTSQGHSPS--STPPVTSVFLSETSGLGKTTDMSRISLEP---GTS 4216 Query: 611 QPQPEGKTSAVVL---------------ADGATIVANPISNPFSAAP-------AATTVV 648 P T+ L AD A S+ +S P A + +V Sbjct: 4217 LPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLV 4276 Query: 649 QTHSQSASTNAPAQ-GSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTS 707 +H T++ + GSS I G+ R T VAS E+S T Sbjct: 4277 TSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERST------SQVASSATETSTVITH 4330 Query: 708 GSPRPAGAK-PKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTA----QQPPPTIPTM 762 S A K++ S T ++ + +++ N P T+ + TI T Sbjct: 4331 VSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQ 4390 Query: 763 IAAASPPSQPAVAL--STIP----GAVPITPPI-----TTIAAAPPPSVTVGGSLSSVLG 811 +Q L ST+P + +TP TT+ + P V S Sbjct: 4391 TGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDV------SWTSP 4444 Query: 812 PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTV 843 P V E + P V+ +PP AT+T+ Sbjct: 4445 PSVAETSYPSSLTPF----LVTTIPP-ATSTL 4471 Score = 45.1 bits (105), Expect = 4e-04 Identities = 207/1012 (20%), Positives = 347/1012 (34%), Gaps = 184/1012 (18%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDE--SGRDSEVSAREHMSSSSSLQSREEKQ-- 93 P++ L+ + + S L A TV + +G +EVS E +S S + S E+ Sbjct: 7536 PASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTM 7595 Query: 94 -EPVVVRPYPQVQMLSTHHAVASATPVAVTAPPA-------HLTPAVPLSFSEG---LMK 142 + + + P++ S A T T P +L A S+ E +++ Sbjct: 7596 SQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQ 7655 Query: 143 PPPKPTM-------------PSRPIAP--APPST-LSLPPKV-PGQVTVTMESSIPQASA 185 P P M PS P +PPS+ LSLP P V+ T + IP S Sbjct: 7656 GFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPP-SP 7714 Query: 186 IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKV 245 +PV ++ P+ I+ T+ + S++ H + A AV S+ Sbjct: 7715 LPVTSLL--TSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNT 7772 Query: 246 TTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSA----TRAQSP 301 N AT + S P TTS +V+ + A R Q+ Sbjct: 7773 GGT--------NVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTE 7824 Query: 302 VITT--------TAAHATDSALSRPTLSIQHPPSAAISIQR--------PAQSR---DVT 342 + ++ + + T S T+ + P A I + PAQS D++ Sbjct: 7825 LASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDIS 7884 Query: 343 TR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN-TIPSATTAGSVSH 400 TR ++ S + T ++ TM T T +T+ T+ T+ +T + SH Sbjct: 7885 TRTVSWFSTSPVMTESAEI-TMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSH 7943 Query: 401 TQAPT-------------STIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP 447 +Q T ++ T PS S ++ TTS PV+ +P+ I+ +SP Sbjct: 7944 SQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESIS-SSPLPVT 8002 Query: 448 DYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPI 507 + H++S PV + + SV + + T +P + T T + Sbjct: 8003 SLLTSGLAKTTDMLHKSS-EPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDV 8061 Query: 508 TSSVS-----------------TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTV 550 +S S T S S T+ G S + P +T+ Sbjct: 8062 GTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTL 8121 Query: 551 DASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQ 610 +G A + + P G A + + S++ + G T Sbjct: 8122 GLRKTSSSEGTSLATEMSTVLSGVPTGA----TAEVSRTEVTSSSRTSISGFAQL---TV 8174 Query: 611 QPQPEGKT-----SAVVLADGATIVANPISNPFSAAPAAT----------------TVVQ 649 P+ +T ++ ++ + A ++ ++P + P +T TV Q Sbjct: 8175 SPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQ 8234 Query: 650 THSQSASTNA----------PAQGS----SPRPSILRKKPATDGMAVRKTLIPPQPPDVA 695 S S T P+Q S S S+L T V TL+ P A Sbjct: 8235 RFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPS--A 8292 Query: 696 SPRVESSMR-------STSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAV 748 S V S + G R G S + + +T +TV ++ + Sbjct: 8293 SLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTED-------M 8345 Query: 749 PPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVG----- 803 P+ + T I+ S ++ S P A T P+ T SV++ Sbjct: 8346 QPSTHTAVTNVRTSISGHESQSS-VLSDSETPKA---TSPMGTTYTMGETSVSISTSDFF 8401 Query: 804 ----------GSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANN 853 SL+S L ++ E ++ S VP AT VS + + + Sbjct: 8402 ETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVL---SEVPSGATTEVSRTEVISSRG 8458 Query: 854 LSMPTSD---LPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLL 902 SM D + P S R I TE + T T +T++ L Sbjct: 8459 TSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTL 8510 Score = 43.9 bits (102), Expect = 8e-04 Identities = 153/781 (19%), Positives = 279/781 (35%), Gaps = 92/781 (11%) Query: 147 PTMPSRPIAPAPPSTLSLP-PKVPGQVTVTMESSIPQASAIPVATISGQQ--GHPSNLHH 203 PT S A + PS S P+VP T T ++ P S+ + G G PS L Sbjct: 2393 PTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPP 2452 Query: 204 IMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAA--VMSSSKVTTVLRP--------TS 253 T+ + A P+ ++ + A+ S+S VT+V P T+ Sbjct: 2453 FTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTT 2512 Query: 254 QLPNAATAQPAVQHIIHQPIQSR-PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATD 312 LP + + H + S P T A V T S+ +++ ++TT+ + A Sbjct: 2513 DLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIH 2572 Query: 313 SALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIF--- 369 S+ PT P++ + + A + +T S L + T+ T+ Sbjct: 2573 SSPQTPT-----TPTSGANWETSATPESLLV-VTETSDTTLTSKILVTDTILFSTVSTPP 2626 Query: 370 ----STGTPVAAATVAPILATNTIP-SATTAGSVSHTQAPTSTIVTMTVPSHSS-HATAV 423 STGT A+ + T IP +AT S T ++ +VT+ S + T + Sbjct: 2627 SKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTL 2686 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 T S + + R P + + P+ SP+ + + S+ V Sbjct: 2687 TMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITV 2746 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSS---------------VSTIRQYPVSAQAPNSAI 528 LP + + + T++ ++T Q S+ S Sbjct: 2747 ALS-TLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGS 2805 Query: 529 TAQTGVGVASTVHL--NPMQLMTVD--------ASHARHIQGIQPAPISTQGIQPAPI-- 576 T TG S++ L NP ++ + A+ + +GI P S + P+ Sbjct: 2806 THSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSA 2865 Query: 577 -GTPGIQPAPLGTQGIHSATPINTQGLQPAPM------GTQQPQPEGKTSAVVLADGAT- 628 +P A L T P +T + + + P P + + +D +T Sbjct: 2866 SSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTA 2925 Query: 629 ---IVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPAT------DG 679 + +P NP + +T + S ++ S PS+ +P D Sbjct: 2926 SSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDP 2985 Query: 680 MAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQ 739 +++ P P +S +S+ S + G +S S ++P+++S E Sbjct: 2986 RYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSG---SSSSPISLSTE----- 3037 Query: 740 NNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT-TIAAAPPP 798 + T + PTA T ++ S QP + + A+ ++P T ++ PP Sbjct: 3038 ---KETSFLSPTASTSRKT--SLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPP 3092 Query: 799 SVTVGGSLSSVLG--PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSM 856 +T +++ G + P ++ S P A SP A+++S+ Sbjct: 3093 ELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPE--TWASSISV 3150 Query: 857 P 857 P Sbjct: 3151 P 3151 Score = 43.5 bits (101), Expect = 0.001 Identities = 205/986 (20%), Positives = 350/986 (35%), Gaps = 164/986 (16%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAA---TVNDESGRDSEVSAREHMSSSSSLQSR 89 P + +PS S +P I +S P + T D G S E ++SS S Sbjct: 5342 PAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSP----ESVTSSPPNLSS 5397 Query: 90 EEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPP---PK 146 + P + + + HH+ +A T+ H + + L+ SE P Sbjct: 5398 ITHERPATYKDTAHTEA-AMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTT 5456 Query: 147 PTMPSRPIAPAPPS-----------TLSLPPKVPGQVTVTMESSIPQA----SAIPVATI 191 T+ ++ + P+ T SL P++ T SS + S +P I Sbjct: 5457 STLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAI 5516 Query: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251 + ++ I ++ +S + P + G + R + + S+++T + Sbjct: 5517 T-----QASRTEISSSRTSISDLDRPTIAPDISTGM--ITRLFTSPIMTKSAEMTVTTQT 5569 Query: 252 TSQ-------LP-----------NAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 T+ LP +T H ++SR P S P V T Sbjct: 5570 TTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETS 5629 Query: 294 SATRAQSPVITTTAAHATDSALSRPT---------LSIQHPPSAAISIQRPAQSRDVTTR 344 S SP +T+ + ++ S S P+ S+ + + P Sbjct: 5630 SGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPN 5689 Query: 345 ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAP 404 ++ P+ L T K HT A T T A A V ++ + S+ A SHT Sbjct: 5690 LSSPTQERLTTYKDTAHTEAMHASMHTNT--AVANVGTSISGHESQSSVPAD--SHTSKA 5745 Query: 405 TSTI-VTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHR 463 TS + +T + T+V+TS + RIQ + SSLIP G R Sbjct: 5746 TSPMGITFAMGD-----TSVSTSTPAFFET----------RIQTE---STSSLIP--GLR 5785 Query: 464 ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQA 523 +TR+ + + L P + + T ITSS +TI S + Sbjct: 5786 --------DTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEV-ITSSRTTISGPDHSKMS 5836 Query: 524 PNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQP 583 P + + L+ +T G I+ Q PIGT I Sbjct: 5837 PY--------ISTETITRLSTFPFVT----------GSTEMAITN---QTGPIGT--ISQ 5873 Query: 584 APLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA 643 A L +A+ T +P+ + P E T+ G + +P S +++P+ Sbjct: 5874 ATLTLDTSSTASWEGTH----SPVTQRFPHSEETTTMSRSTKGVS-WQSPPSVEETSSPS 5928 Query: 644 ATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSM 703 + + + +S + GSSP ++ T G RKT+ D S V SS+ Sbjct: 5929 SPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGR--RKTI---DMLDTHSELVTSSL 5983 Query: 704 RST---SGSPRPAGAKPKSE-IHVSMATPVTVSMETVSNQNNDQPTIAV--PPTAQQPPP 757 S SG + A +E IH S T T +M T ++ + ++++ P+ PP Sbjct: 5984 PSASSFSGEILTSEASTNTETIHFSENTAET-NMGTTNSMHKLHSSVSIHSQPSGHTPPK 6042 Query: 758 TIPTM----IAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGS--LSSVLG 811 +M I + S P P P+TP + + A + T + SSV Sbjct: 6043 VTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSL 6102 Query: 812 PPVPEIKVKEEVEPMDIMRPVSA-------VPPLATNTVSPSLAL-LANNLSMPTSDLPP 863 E+ E P SA + P A+++ S S L ++ + ++ T P Sbjct: 6103 DAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPS 6162 Query: 864 GASPRKKPRKQQHVISTEEG-------DMMETNST----DDEKSTAKSLLVKAEKRKSPP 912 G + + I+T G D +++ +T +D K+ AE+ S Sbjct: 6163 GVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANS-- 6220 Query: 913 KEYIDEEGVRYVPVRPRPPITLLRHY 938 + + V P P + L+ + Sbjct: 6221 ---LSSQAPLLVTTSPSPVTSTLQEH 6243 Score = 43.5 bits (101), Expect = 0.001 Identities = 185/866 (21%), Positives = 311/866 (35%), Gaps = 147/866 (16%) Query: 78 EHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS 137 E SSSSSL S P + P P V + P + + P HLT ++P S Sbjct: 6506 EKTSSSSSLLSL-----PAITSPSP----------VPTTLPESRPSSPVHLT-SLPTS-- 6547 Query: 138 EGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG-----QVTVTMESSIPQASAIPVATIS 192 GL+K T +A PP+ S K+P + T M S A T S Sbjct: 6548 -GLVKT----TDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTS 6602 Query: 193 GQQGH--------PSNLHHIMTT--NVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSS 242 ++ + P + M T N++ +I+ ++ PG +S + R + S+ Sbjct: 6603 EKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPG------SSEITR----IEMEST 6652 Query: 243 SKVTTVLR--PTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 + L+ TSQ P +T + AV H + T+ A + S+ R Sbjct: 6653 FSLAHGLKGTSTSQDPIVSTEKSAVLHKL-----------TTGATETSRTEVASSRRTSI 6701 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 P H+T+S P +S + PS IS+ +S ++T I + P LG+ Q Sbjct: 6702 P----GPDHSTES----PDISTEVIPSLPISLGI-TESSNMT--IITRTGPPLGSTSQGT 6750 Query: 361 HTMAQKTIFSTGTPVAAATVA-------------PILATNTIPSATTAGSVSHTQAP--- 404 T+ T S + AT P + + TIP + S S + P Sbjct: 6751 FTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPA 6810 Query: 405 -TSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHR 463 TS V+ T+P + TS + + V+ TSP P SS + H Sbjct: 6811 MTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSS----TSHE 6866 Query: 464 ---ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVS 520 + A+E + + + + + LA T T+ + T + Sbjct: 6867 ILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHT 6926 Query: 521 AQAPNSAITAQ-TGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 + + +++++ T + ST L P G++ IS Q A T Sbjct: 6927 TVSTSMSVSSETTKIKRESTYSLTP---------------GLRETSIS----QNASFSTD 6967 Query: 580 G---IQPAPLGTQGIHSATPINTQGLQPAP---MGTQQPQPEGKTSAVVLADGATIVANP 633 + P GT S T + + G P T P+ +T + A + Sbjct: 6968 TSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAE 7027 Query: 634 ISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPD 693 ++ P P+ +T T + ST + ++ ++ P ++ TL+ P D Sbjct: 7028 MTIPTQTGPSGSTSQDTLTLDTSTT--KSQAKTHSTLTQRFPHSE----MTTLMSRGPGD 7081 Query: 694 V---ASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 750 + +SP +E+ S PA P +S PVT+S + + + P Sbjct: 7082 MSWQSSPSLENPSSLPSLLSLPATTSPPP---ISSTLPVTISSSPLPVTS---LLTSSPV 7135 Query: 751 TAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVL 810 T T P ++ +SPP LS T TT A PS + S+V Sbjct: 7136 TTTDMLHTSPELV-TSSPPK-----LSHTSDERLTTGKDTTNTEAVHPSTNT--AASNVE 7187 Query: 811 GPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK 870 P + + + S P T+T + ++ + TS + + Sbjct: 7188 IPSSGHESPSSALADSETSKATS--PMFITSTQEDTTVAISTPHFLETSRIQKESISSLS 7245 Query: 871 PRKQQHVISTEEGDMMETNSTDDEKS 896 P+ ++ S E +ET++ E S Sbjct: 7246 PKLRETGSSVETSSAIETSAVLSEVS 7271 Score = 42.7 bits (99), Expect = 0.002 Identities = 175/885 (19%), Positives = 315/885 (35%), Gaps = 156/885 (17%) Query: 106 MLSTH--HAVASATPVAVTAPPAHLTPAVP------LSFSEGLMKPPPKPTMPSRPIAPA 157 M TH ++ T + +A P+HLT P S SE P SR I Sbjct: 1562 MSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETG 1621 Query: 158 PPSTLSLPPKVPGQVTVTMESS---------IPQASAIPVATISGQQGHPSNLHHIMTTN 208 P + S PP T T SS +P ++ P T + + ++ Sbjct: 1622 PTNIQSTPPM---DNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMA 1678 Query: 209 VQMSIIRSNAPGPPLHIG----ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 M ++ ++APG + +S L SS + L +++ +P+ Sbjct: 1679 GTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPS 1738 Query: 265 V----QHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL 320 Q P+ S P I + T T + I+ ++A S+ + + Sbjct: 1739 YAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMST 1798 Query: 321 SI--------QHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTG 372 ++ + +A++ + P S +VT I+L A T S G Sbjct: 1799 ALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNT--------TDSLDLSHG 1850 Query: 373 TPVAAA-TVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVA 431 ++A T+A + NT T A + + +S ++M +S+H + T V+ Sbjct: 1851 VHTSSAGTLATDRSLNT--GVTRASRLENGSDTSSKSLSM---GNSTHTSMTYTEKSEVS 1905 Query: 432 KVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPT 491 + PR + P ++L G+RA + S+PV+ Sbjct: 1906 SSI-------HPRPETSAPGAETTLTSTPGNRAISLTLPFS-------SIPVEEVISTGI 1951 Query: 492 YPPSAYPLAAHTYTPIT------SSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 A T++PIT +S TI Q S Q ++ + + V ST ++N + Sbjct: 1952 TSGPDINSAPMTHSPITPPTIVWTSTGTIEQ---STQPLHAVSSEKVSVQTQSTPYVNSV 2008 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPA 605 + + +H + S+ +P + ++ T +A L + Sbjct: 2009 AV-SASPTHENSV--------SSGSSTSSPYSSASLESLD-STISRRNAITSWLWDLTTS 2058 Query: 606 PMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSS 665 T P + + L+ G + V+NP S TT +AST+A Q Sbjct: 2059 LPTTTWPST---SLSEALSSGHSGVSNPSS---------TTTEFPLFSAASTSAAKQ--- 2103 Query: 666 PRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSG-SPRPAGAKPKSEIHVS 724 + P T+ P + A+ + + S +G S P GA SE+ + Sbjct: 2104 -------RNPETETHG---------PQNTAASTLNTDASSVTGLSETPVGASISSEVPLP 2147 Query: 725 MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP---- 780 MA + +++++ P++ TA + I+ + S + ++ P Sbjct: 2148 MAITSRSDVSGLTSESTANPSLG---TASSAGTKLTRTISLPTSESLVSFRMNKDPWTVS 2204 Query: 781 ---GAVPITPPITTI---AAAPPPSVTVGG-----------SLSSVLGPPVPEIKVKE-- 821 G+ P T T+I +A PP TV S+ +V P P+ +V Sbjct: 2205 IPLGSHPTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTIS 2264 Query: 822 --EVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVIS 879 + R +S++ T+ V+P + + +S S P GASP +++ + S Sbjct: 2265 HFPEKTTHSFRTISSLTHELTSRVTP---IPGDWMSSAMSTKPTGASPSITLGERRTITS 2321 Query: 880 ----------TEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKE 914 T T S D+E + S ++ A K P + Sbjct: 2322 AAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSD 2366 Score = 41.2 bits (95), Expect = 0.005 Identities = 172/897 (19%), Positives = 298/897 (33%), Gaps = 181/897 (20%) Query: 119 VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPK---VPGQVTVT 175 V+ T+PP+ + P SF P T PS + P LS P G V +T Sbjct: 5026 VSWTSPPSVDKTSSPSSFLSS-----PAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKIT 5080 Query: 176 ---------MESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 + SS+P S+ ++ + + N + + +++N G H Sbjct: 5081 DILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSP 5140 Query: 227 A---SHLPRG---------------AAAAAVMSSSKVTTVLRP-----TSQLPNAATAQP 263 A S P+ + + V SS+ T + R T +L +T+Q Sbjct: 5141 ALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQ- 5199 Query: 264 AVQHIIHQPIQSRPPVTTS---NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL 320 +S P TS + +P + VS+T S +T H S + T Sbjct: 5200 ----------ESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDH-DKSTVPPDTF 5248 Query: 321 SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGT-PKQQLHTMAQKTIFSTGTP----- 374 + + P SI+ + +TT+ + P + T P T++Q ST T Sbjct: 5249 TGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYS 5308 Query: 375 ------------VAAATVAPILATNTI------PSATTAGSVSHTQA------------- 403 V+ T P+ T+++ P+ T+ VS T Sbjct: 5309 EVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTAL 5368 Query: 404 PTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHR 463 PTS +VT T ++ +VT+S ++ ITH P D A + + S + Sbjct: 5369 PTSVLVTTTDVLGTTSPESVTSSPPNLS-----SITHERPATYKD-TAHTEAAMHHSTNT 5422 Query: 464 ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQA 523 A N + ++ SV + TP+ S+ ST+ VS Sbjct: 5423 AVTNVGTSGSGHKSQSSVLADSE--------------TSKATPLMSTTSTLGDTSVSTST 5468 Query: 524 PNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQP 583 PN + T Q + T L+P ++ + S + T Sbjct: 5469 PNISQTNQ--IQTEPTASLSPR---------------LRESSTSEKTSSTTETNT-AFSY 5510 Query: 584 APLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIV---ANPISNPFSA 640 P G S T I++ + + P+ T + + I+ A + Sbjct: 5511 VPTGAITQASRTEISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTT 5570 Query: 641 APAATTV------VQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPP-- 692 P AT+ T T++ P I + T G T P + Sbjct: 5571 TPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSS 5630 Query: 693 --DVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 750 + SP + S +S SP + P ++ T V V+ V + +P + PP Sbjct: 5631 GFSLMSPSMTSPSPVSSTSPESIPSSPLPV--TALLTSVLVTTTNVLGTTSPEPVTSSPP 5688 Query: 751 TAQQPP--------------------------PTIPTMIAA----ASPPSQPAVALSTIP 780 P + T I+ +S P+ + +T P Sbjct: 5689 NLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSP 5748 Query: 781 GAVPITPPITTIAAAPPP--SVTVGGSLSSVLGPPVPEIKVKEEVEPM-DIMRPVSAVPP 837 + T+++ + P + +S L P + + + EE+ + + +S VP Sbjct: 5749 MGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPT 5808 Query: 838 LATNTVSPSLALLANNLSMPTSD---LPPGASPRKKPRKQQHVISTEEGDMMETNST 891 T VS + + ++ ++ D + P S R T +M TN T Sbjct: 5809 TTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQT 5865 Score = 36.2 bits (82), Expect = 0.17 Identities = 104/553 (18%), Positives = 199/553 (35%), Gaps = 57/553 (10%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 PVT +P +T ++P T S + S +A +S+ PA+ Sbjct: 157 PVTEKYTVPTET-STTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMT-PAE 214 Query: 338 SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA--TVAPILATNTIP-SATT 394 + + ++P+ GT ++ K GTP + ++ IL+T P S+ Sbjct: 215 TTVTDSHTPGRTNPSFGTLYSSFLDLSPK-----GTPNSRGETSLELILSTTGYPFSSPE 269 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 GS H++ TS + S + +V + I + Q + TSP + P P R+ Sbjct: 270 PGSAGHSRISTSAPL--------SSSASVLDNKISETSIFSGQ-SLTSP-LSPGVPEARA 319 Query: 455 SLIPISGHRASPNPVAMETRSDN-RPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVST 513 S +P S S ET ++ R ++ + T + L H + ST Sbjct: 320 STMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPST 379 Query: 514 IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH-IQGIQPAPISTQGIQ 572 ++++ S T G ++ +P + + ++ H G + + Sbjct: 380 HIAKTLASEWLGSPGTLG-GTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMT 438 Query: 573 PAPIGTPGIQPAPLGTQ-GIHSATPINTQGLQPAPMGTQQPQPE--------GKTSAVVL 623 P PG + T T ++++ P+ + + P E G+ S+ Sbjct: 439 PLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTA 498 Query: 624 ADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKP--ATDGMA 681 A G++ + ++ S A + T+ ++ +Q S Q PS+ ++P +T A Sbjct: 499 AHGSSDILRATTSSTSKASSWTS--ESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAA 556 Query: 682 VRKTLIPPQPPDVASPRVESSM--------------RSTSGSPRPAGAKPK-------SE 720 T +P + + S+ ST+G A P S Sbjct: 557 PITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSS 616 Query: 721 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 780 S T ++ T S++ + T+A P + A +SPP + + + Sbjct: 617 TRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVS 676 Query: 781 GAVPITPPITTIA 793 +P T + + A Sbjct: 677 SVIPETSSLQSSA 689 Score = 35.8 bits (81), Expect = 0.23 Identities = 152/818 (18%), Positives = 288/818 (35%), Gaps = 108/818 (13%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR---EEKQE 94 P +SQA + S +A + V E + + S QS EE Sbjct: 5867 PIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSS 5926 Query: 95 PVVVRPYPQVQMLST-HHAVASATPVAVTAPPAHLTPAVPLS--FSEGLMKPPPKPTMPS 151 P P P + S+ + AV+ ++P T A+P++ + G K S Sbjct: 5927 PSSPVPLPAITSHSSLYSAVSGSSP----------TSALPVTSLLTSGRRKTIDMLDTHS 5976 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM 211 + + PS S ++ T +I S T G LH ++ + Q Sbjct: 5977 ELVTSSLPSASSFSGEILTSEASTNTETI-HFSENTAETNMGTTNSMHKLHSSVSIHSQP 6035 Query: 212 S---------------IIRSNAPGPPLHIGASH---------LPRGAAAAAVMSSSKVTT 247 S I+ ++ PG P L + A + S+++ T Sbjct: 6036 SGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNT 6095 Query: 248 VLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA 307 V S +AAT + + P + P + + P + S++ + SP +T + Sbjct: 6096 VFSSVSL--DAATEVSRAEVTYYDP--TFMPASAQSTKSPDISPEASSSHSNSPPLTIS- 6150 Query: 308 AHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTP----------- 356 + T++ Q PS S+ + + D +T T P+ T Sbjct: 6151 --------THKTIATQTGPSGVTSLGQ--LTLDTSTIATSAGTPSARTQDFVDSETTSVM 6200 Query: 357 KQQLHTMAQKTIFSTGTPVAAATVAPILAT-------NTIPSATTAGSVSHTQAPTSTIV 409 L+ + + + FS + ++ AP+L T +T+ +T+ VS T PT T+ Sbjct: 6201 NNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLA 6260 Query: 410 TMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPV 469 +T + + N+ + T T +P+ +++ + G +SPN Sbjct: 6261 KITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTM----HPSINTAVANV-GTTSSPNEF 6315 Query: 470 AMETRSDNRP--------SVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521 D+ P + T P + + S + +R+ S Sbjct: 6316 YFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQ 6375 Query: 522 QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI----STQGIQPAP-- 575 + +S+ T+ T A T + + +S IQG + + ST+ + Sbjct: 6376 KIGSSSDTS-TVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTF 6434 Query: 576 IGTPGIQPAPLGTQ-GIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPI 634 G + + TQ G H AT T + +Q T D +T+ + Sbjct: 6435 AGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSR-- 6492 Query: 635 SNPFSAAPAATTVVQTHSQSASTNAPAQGS-SPRPSIL-RKKPATDGMAVRKTLIPPQPP 692 + + + +V +T S S+ + PA S SP P+ L +P++ V T +P Sbjct: 6493 VPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSS---PVHLTSLPTSGL 6549 Query: 693 DVASPRVES--SMRSTSGSPRPAGAKPKSEIH--VSMATPVTVSMETVSNQNNDQPTIAV 748 + + S S+ GS +I M +++ V +++ + + Sbjct: 6550 VKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSS 6609 Query: 749 PPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPIT 786 P +PP M+ + + + + +++PG+ IT Sbjct: 6610 VPAYSEPPKVTSPMVTSFN--IRDTIVSTSMPGSSEIT 6645 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 100 bits (249), Expect = 7e-21 Identities = 163/788 (20%), Positives = 271/788 (34%), Gaps = 126/788 (15%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPP 159 P P + + T A +P PP + PL+ G PP T S A A Sbjct: 1100 PTPTLSLKPTPPAPVRLSPAP---PPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATT 1156 Query: 160 STLSLPPKVPGQVTVT--MESSIPQASAI-----------PVA----------------- 189 + + P P ++ ++ M++ +P + PVA Sbjct: 1157 TAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKL 1216 Query: 190 TISGQQ------GHPSNL-------------HHIMTTNVQMSIIRSNAPGP---PLHIGA 227 T++G Q G P L HH+++ +++I++ AP P P+ + Sbjct: 1217 TLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLP 1276 Query: 228 SHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP- 286 S P A +S + PT + N + V+ + PP+ + P Sbjct: 1277 SSTPSTTPAPTGLSLPLAANQVPPT-MVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPS 1335 Query: 287 ---PAVV---ATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRD 340 PAV+ T++ R +P + T A L RP L + H PS +S P + Sbjct: 1336 SGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAA-- 1393 Query: 341 VTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH 400 I+ P H P M +PV++ P+ ++ I TT + + Sbjct: 1394 -PLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPA- 1451 Query: 401 TQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPIS 460 AP + ++ + +S +T+ P+A VVP P + P + +S + + Sbjct: 1452 -SAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPA--APGPPSLAPSGASPSASALTLG 1508 Query: 461 -------------GHRASPNPVAMETRSDNRPSVPVQFQYFLPT------YP--PSAYPL 499 GH P + N P +P +P P+ P Sbjct: 1509 LATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPA 1568 Query: 500 AAHTYTPITSSVSTIRQYPVSAQAPNSAITAQT---------------GVGVASTVHLNP 544 A P +S+ + AP +AI A + G P Sbjct: 1569 QASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTP 1628 Query: 545 MQLMTVDASHARHIQGIQP--------APISTQGIQPAPIGTPGIQPAPLGTQGIHSATP 596 + +M ++ + P AP STQ + PAP+ +P PA T + A Sbjct: 1629 VPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALA 1688 Query: 597 INTQGLQPAP---MGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQ 653 G P+ +GT PQ T + L +++V P A QT S Sbjct: 1689 PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSL 1748 Query: 654 S-ASTNAPAQGSSPRPS-ILRKKPATDGMAVRK-------TLIPPQPPDVASPRVESSMR 704 + A APA P P+ L PA+ ++ TL P P + ++ Sbjct: 1749 APAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLAL 1808 Query: 705 STSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIA 764 + + + PA + S A P+ V+M + + D+P + PP+ T Sbjct: 1809 APASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFG 1868 Query: 765 AASPPSQP 772 P QP Sbjct: 1869 GPRPRRQP 1876 Score = 92.0 bits (227), Expect = 3e-18 Identities = 216/914 (23%), Positives = 333/914 (36%), Gaps = 135/914 (14%) Query: 97 VVRPYPQVQ---MLSTHHAVASATPVAVTAPP-----AHLTPA-VPLSFSEGLM---KPP 144 +++P P+ + ++ ++ A PV V PP A TP VP LM P Sbjct: 997 MLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPA 1056 Query: 145 PKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPS-NLHH 203 P +P A PP + LPP P S+PQ P+ +SG P+ L Sbjct: 1057 GPPLIP----ASRPPGPVLLPPLQPNS------GSLPQVLPSPLGVLSGTSRPPTPTLSL 1106 Query: 204 IMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQP 263 T + + + PG + +P G +++ TT T+ A T P Sbjct: 1107 KPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPT--P 1164 Query: 264 AVQHIIHQP-IQSRPPVTTSNAIPPAVVATVS--ATRAQSPVITTTAAHATDSAL--SRP 318 A Q +I P +Q+R +P V ++ A+ AQ PV + + ++ Sbjct: 1165 APQRLILSPDMQAR--------LPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKL 1216 Query: 319 TLSIQHPPSAAISIQRPAQSRDVTT--------RITLPSHPALGTPKQQLHTMAQKTIFS 370 TL+ A+ RP Q V I+ P+H AL ++ Sbjct: 1217 TLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLP 1276 Query: 371 TGTPVAAATVAPI-----LATNTIPSA----TTAGSVSHTQAPTS--TIVTMTVPSHSSH 419 + TP + T AP LA N +P T + QAP T V P+ Sbjct: 1277 SSTP--STTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP 1334 Query: 420 ATAVTTSNIPVAKVVPQQI-THTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNR 478 ++ + P + P ++ T T + P + + P+ SP+P + Sbjct: 1335 SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTP-TLVRPLLKLVHSPSPEVSASAPGAA 1393 Query: 479 P---SVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVG 535 P S P+ LP P++ P+ +P+ S VS+ P+S+ P S T T Sbjct: 1394 PLTISSPLHVPSSLPG--PASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPT--TLPA 1449 Query: 536 VASTVHLNPMQL-MTVDASHARHIQGIQP--APISTQGIQPAPIGTPGIQPAP----LGT 588 AS P+ +TV AS + + P AP+ P + G P+ LG Sbjct: 1450 PASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGL 1509 Query: 589 QGIHSATPINTQG--LQPAPMGTQQPQPEGKTSAVVLADGATIV-ANPISNPFSAAP--- 642 S + T G L AP + P G S V A +V A+ +++PF +AP Sbjct: 1510 ATAPSLSSSQTPGHPLLLAPTSSHVP---GLNSTVAPACSPVLVPASALASPFPSAPNPA 1566 Query: 643 --AATTVVQTHSQSASTNAP-AQGSSPRPSILRKKPATDGMAVRKTLIP----------- 688 A+ + S S + P A ++P+ +IL PA +A L P Sbjct: 1567 PAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPP-LAPLPVLAPSPGAAPVLASS 1625 Query: 689 --PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTI 746 P P S +S+ S S P P S + PV + + ++ Sbjct: 1626 QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP 1685 Query: 747 AVPPTAQQPPPTIPTMIAAASPPSQ-PAVALSTIPGAVPITPPITTIAAAPPPSVTVGGS 805 A+ PT P+ + +P P LS P + + P T++ AP P + + Sbjct: 1686 ALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQT 1745 Query: 806 LSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTV-----SPSLALLANNLSMPTSD 860 LS PP + P S V P +T+ S S +LLA S+ T Sbjct: 1746 LSLAPAPP---------------LAPASPVGPAPAHTLTLAPASSSASLLA-PASVQTLT 1789 Query: 861 LPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEG 920 L P P P Q + + ST S A SL+V A P + Sbjct: 1790 LSPAPVPTLGPAAAQTL-------ALAPASTQSPASQASSLVVSASGAAPLPVTMVSR-- 1840 Query: 921 VRYVPVRPRPPITL 934 +PV P TL Sbjct: 1841 ---LPVSKDEPDTL 1851 Score = 49.3 bits (116), Expect = 2e-05 Identities = 99/475 (20%), Positives = 165/475 (34%), Gaps = 94/475 (19%) Query: 396 GSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP---DYPAE 452 G+ + TQ T P S+H T TT+ P +++ +PR +P PA Sbjct: 2401 GARAETQGANHT------PVISAHQTRSTTTP-PRCSPARERVPRPAPRPRPTPASAPAA 2453 Query: 453 RSSLIPISGHR----ASPNPVAMETRSDNRPSVPVQFQYFLP-------TYPPSAYPLAA 501 +L+P+ ++PNP+ + PS P Q +P T PP+ P A Sbjct: 2454 IPALVPVPVSAPVPISAPNPITI-LPVHILPSPPPPSQ--IPPCSSPACTPPPACTPPPA 2510 Query: 502 HTYTPITSSVSTIRQ--------YPVSAQAPNSAITAQTGVGVASTVHLNP--MQLMTVD 551 HT P + + T P+SA N + + + + +P ++L +V Sbjct: 2511 HTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVA 2570 Query: 552 ASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQ----------GIHSATPINTQG 601 +S + + P + ++ P+ + P G P + +G Sbjct: 2571 SSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEG 2630 Query: 602 --LQPAPMGTQQPQPEGKTSAVVLADGA-------------------TIVANPISNPFSA 640 L P G + P +++ + L A T P S+P Sbjct: 2631 TTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKP 2690 Query: 641 APAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRV- 699 T V S S+S + +G SP R+ A + + T P QPP P+V Sbjct: 2691 QELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPP---GPKVL 2747 Query: 700 ------------ESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA 747 E + R A + + + A+P + S+ ++S + P Sbjct: 2748 RKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGG 2807 Query: 748 VPPTAQQPPPTIPTMIAAASPPSQPAVA-----LSTIPGAVPITPPITTIAAAPP 797 P P ++PT PP QP +A L G P +A PP Sbjct: 2808 --PCEAAPSSSLPT------PPQQPFIARRHIELGVTGGGSPENGDGALLAITPP 2854 Score = 46.6 bits (109), Expect = 1e-04 Identities = 186/956 (19%), Positives = 311/956 (32%), Gaps = 141/956 (14%) Query: 7 PQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVND 66 P AG+ + G GGG + S++ P T +S+ + A Sbjct: 2364 PGAGDESSCGTGGGTHRR----SKKAKAPERPGTRVSER------------LRGARAETQ 2407 Query: 67 ESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-- 124 + +SA + S+++ + ++ P P+ S A+ + PV V+AP Sbjct: 2408 GANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVP 2467 Query: 125 ----------PAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPP--KVPGQV 172 P H+ P+ PPP P A PP + PP P Sbjct: 2468 ISAPNPITILPVHILPS----------PPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQ 2517 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 T + S P P IS TN+ + + P L A P Sbjct: 2518 TCLVTPSSPLLLGPPSVPISAS-----------VTNLPLGL----RPEAELCAQALASPE 2562 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 A+V SS + L P L A V S P +T P Sbjct: 2563 SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ 2622 Query: 293 VSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS--IQRPAQSRDVTTRITLPSH 350 + A+ +T + ++ PPSAA +Q P ++ + +T Sbjct: 2623 EAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT 2682 Query: 351 PALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVT 410 P K Q A+ ST + ++ P A P T+ V T Sbjct: 2683 PTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARP--PRRRTSADVEIRGQGTGR--- 2737 Query: 411 MTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP-ISGHRASPNPV 469 P + + VV ++ R Q S+L+P +S ASP Sbjct: 2738 ---PGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQ---RGAASTLVPGVSETSASPGSP 2791 Query: 470 AMETRSDNRPSVPV------QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQA 523 ++ + S S P+ LPT P + H +T S + Sbjct: 2792 SVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGG--------GSPEN 2843 Query: 524 PNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIS-----TQGIQPAP--- 575 + A+ A T V P + + S A +G+ AP S T G P P Sbjct: 2844 GDGALLAITPPAVKRRRGRPPKK----NRSPADAGRGVDEAPSSTLKGKTNGADPVPGPE 2899 Query: 576 ---IGTPGIQ------PAPLGTQGIHS----ATPINTQGLQPAPMGTQQPQPEGKTSAVV 622 + P ++ P PLG Q +H +P+ + P P P +SA Sbjct: 2900 TLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSA-- 2957 Query: 623 LADG-ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMA 681 DG + P +P P +V + A+T S+ P R +P + + Sbjct: 2958 -GDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPS 3016 Query: 682 VRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNN 741 R + +P D S +ES P+ G S + P+T Sbjct: 3017 PRPSQLPVLDRDSTSV-LESCGLGRRRQPQGQGESEGSSSDEDGSRPLT----------- 3064 Query: 742 DQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVT 801 + + + + +M+ A + PG + +TPP+ ++ + Sbjct: 3065 RLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLA--DSGPGGLELTPPVVSLTPKLRSTRL 3122 Query: 802 VGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLA-------TNTVSPSLALLANNL 854 GSL VP ++ E++ PV P LA + + P ++ + Sbjct: 3123 RPGSL-------VPPLET-EKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEA 3174 Query: 855 SMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKS 910 + +PR++P ++ V +T +GD S+ ++ + K K+ Sbjct: 3175 EASGEEEEGDGTPRRRPGPRRLVGTTNQGDQRILRSSAPPSLAGPAVSHRGRKAKT 3230 Score = 38.1 bits (87), Expect = 0.045 Identities = 54/239 (22%), Positives = 87/239 (36%), Gaps = 54/239 (22%) Query: 692 PDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPT 751 P+ RV +R + A P H + +T T + + + +P PT Sbjct: 2388 PERPGTRVSERLRGARAETQGANHTPVISAHQTRST-TTPPRCSPARERVPRPAPRPRPT 2446 Query: 752 AQQPPPTIPTMI----AAASPPSQP----AVALSTIPGAVPIT--PPITTIAAAPPPSVT 801 P IP ++ +A P S P + + +P P + PP ++ A PPP+ T Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACT 2506 Query: 802 VGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTS-- 859 PP P PP T V+PS LL S+P S Sbjct: 2507 ----------PP-----------------PAHTPPPAQTCLVTPSSPLLLGPPSVPISAS 2539 Query: 860 --DLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYI 916 +LP G P + Q + + +E S ++++ SL+ PPK+ + Sbjct: 2540 VTNLPLGLRPEAELCAQ----ALASPESLELASVASSETSSLSLV--------PPKDLL 2586 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 100 bits (248), Expect = 1e-20 Identities = 205/934 (21%), Positives = 328/934 (35%), Gaps = 121/934 (12%) Query: 51 NSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTH 110 +S S G P V D S + + H++S SS + + PV +ST Sbjct: 3175 SSVSTGHATPLL-VTDASSASTGHATPLHVTSPSSASTGDTTPVPVT-----DTSSVSTG 3228 Query: 111 HAVASATPVAVTAPPAHLT------PAVPLSF-SEGLMKPPPKPTMPS------RPIAPA 157 HA TP+ VT + T P +S S G P P S P+ Sbjct: 3229 HA----TPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVT 3284 Query: 158 PPSTLSLPPKVPGQVTVTMESSIPQASAIPV-ATISGQQGHPSNLHHIMTTN-------- 208 PS+ S P VT T +S A+ +PV +T S GH + L T++ Sbjct: 3285 SPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTP 3344 Query: 209 --VQMSIIRSNAPGPPLH--IGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 V S PLH I +S + V +S +T + LP T+ + Sbjct: 3345 LPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSAST--GHATPLPVTDTSSVS 3402 Query: 265 VQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL---- 320 H P+ S V+T + P V SA+ Q+ + T+ + + + P L Sbjct: 3403 TGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDA 3462 Query: 321 ---SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTG--TPV 375 S H ++ A + D TTR+ + + T + + + STG TP+ Sbjct: 3463 SSVSTGHATPLPVTDTSSASTGD-TTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPL 3521 Query: 376 AAATVAPILATNTIPSATTAGSVSHTQAPTSTIVT--------------MTVPSHSS--H 419 + + + P T S + T T VT +T+PS SS H Sbjct: 3522 LVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGH 3581 Query: 420 ATAV---TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 T + +TS++ V P +T S + +P++ ++ A Sbjct: 3582 TTPLPVTSTSSVSTGHVTPLHVTSPSSA-----STGHVTPLPVTSTSSASTGHATPLLVT 3636 Query: 477 NRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 + SV LP S+ T P+T + S + QA +T+ + V Sbjct: 3637 DASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSAS-----TGQATPLPVTSLSSVST 3691 Query: 537 ASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATP 596 T L + HA + P+ +ST P P+ +P + ATP Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSP-------SSASTGHATP 3744 Query: 597 INTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATT-VVQTHSQSA 655 + GL A G P P TS+ + P+++ SA+ TT + T SA Sbjct: 3745 LPVTGLSSASTGDTTPLPVTDTSSASTRHATPL---PVTDTSSASTDDTTRLPVTDVSSA 3801 Query: 656 STN-----APAQGSSPRPSILRKKPATDGMAV---RKTLIPPQPPDVAS-------PRVE 700 ST SS P TD +V T +P AS P + Sbjct: 3802 STGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTD 3861 Query: 701 SSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP 760 +S ST G P S + ATP+ V+ + ++ + P ++ T P Sbjct: 3862 TSSVST-GHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTP 3920 Query: 761 TMIAAASPPS----------QPAVALSTIPGAVPITPPIT-TIAAAPPPSVTVGGSLSSV 809 + AS S P+ A +P+T + + A P +T S+S+ Sbjct: 3921 LPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTG 3980 Query: 810 LGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVS------PSLALLANNLSMPTSDLPP 863 P+P PV+++ ++T + PS A + S+P +D Sbjct: 3981 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASS 4040 Query: 864 GASPRKKPRKQQHVISTEEGDMMETNSTDDEKST 897 ++ P S GD TD ++ Sbjct: 4041 VSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSAS 4074 Score = 99.8 bits (247), Expect = 1e-20 Identities = 183/806 (22%), Positives = 290/806 (35%), Gaps = 93/806 (11%) Query: 113 VASATPVAVT---------APPAHLTPAVPLSFSEGLMKPPPKPTMPSR----PIAPAPP 159 +++ATP+ VT P H+T A +S P P+ S P+ Sbjct: 971 ISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDT 1030 Query: 160 STLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNLHHIMTTNVQMSIIRSNA 218 S+ S P VT +S ++ +PV T S GH + L T++ + Sbjct: 1031 SSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLP---VTSLSSASTGDTT 1087 Query: 219 PGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPP 278 P P ++ A + V +S V+T T+ LP T+ + H P+ Sbjct: 1088 PLPVTDTSSASTGH-ATSLPVTDTSSVST--GHTTPLPVTDTSSASTGHATSLPVTDTSS 1144 Query: 279 VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQS 338 V+T + P V SA+ Q+ + T+ + + + P L + P SA+ P Sbjct: 1145 VSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP-LPVTSPSSASTGHATPLLV 1203 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 D ++ T TP + T +T PV + A T +P T S Sbjct: 1204 TDTSSAST-----GHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLP-VTDTSSA 1257 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVVPQQITH-TSPRIQPDYPAERS 454 S QA TS +VT T + T + +TS+ V P +T +S P + Sbjct: 1258 STGQA-TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVT 1316 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVP--------VQFQYFLPTYPPSAYPLAAHTYTP 506 SL S P PV + + + P V + P + A + TP Sbjct: 1317 SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATP 1376 Query: 507 IT----SSVSTIRQYPVSAQAPNSAITAQ------TGVGVASTVHLNPMQLM---TVDAS 553 + SSVST P+ +P+SA T T AST H P+ + +V Sbjct: 1377 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1436 Query: 554 HARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ 613 HA + P+ ST P P+ + AT + G P Sbjct: 1437 HATSLPVTIPSAASTGHTTPLPV-------TDTSSASTGQATSLLVTDTSSVSTGDTTPL 1489 Query: 614 PEGKTSAVVLADGATIVANPISNPFSAAPA-ATTVVQTHSQSASTN--------APAQGS 664 P TS+ A + +++P SA+ AT + T SAST +P+ S Sbjct: 1490 PVTSTSS---ASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAS 1546 Query: 665 SPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVS 724 + + L P TD +V P P V S +++G P S Sbjct: 1547 TGDTTPL---PVTDASSVSTGHTTPLP-------VTSPSSASTGHTTPLPVTDTSSASKG 1596 Query: 725 MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVP 784 TP+ V+ + ++ + P ++ T P + AS +LST A P Sbjct: 1597 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNAS-------SLST-GHATP 1648 Query: 785 I---TPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 841 + +P + A P VT S S+ P+P + PV+ V +T Sbjct: 1649 LHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTG 1708 Query: 842 TVSPSLALLANNLSMPTSDLPPGASP 867 +P +++S + P SP Sbjct: 1709 QATPLPVTSLSSVSTGDTTPLPVTSP 1734 Score = 97.8 bits (242), Expect = 5e-20 Identities = 198/871 (22%), Positives = 310/871 (35%), Gaps = 93/871 (10%) Query: 39 STG-LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 STG + P +S S G P V D S + + ++S SS+ + + PV Sbjct: 2762 STGHATPLPLTSLSSVSTGDTTPLP-VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVT 2820 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL---SFSEGLMKPPPKPTMPSRPI 154 ST HA + +A H TP S S G P S I Sbjct: 2821 -----DTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASI 2875 Query: 155 APAPP------STLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNLHHIMTT 207 A S++S P VT +S A+ +PV T S GH + LH Sbjct: 2876 GHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLH----V 2931 Query: 208 NVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQH 267 S +A P+ +S A V S S V+T T+ LP + + + H Sbjct: 2932 TSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVST--GDTTPLPVTSPSSASTGH 2989 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPV--ITTTAAHATDSALSRPTLSIQHP 325 P+ +T A V +T SA+ + +T T++ +T A P S+ Sbjct: 2990 TTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSS- 3048 Query: 326 PSAAISIQRPAQSRDVTTR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPIL 384 + D T +T PS + G L T A TP+ +++ + Sbjct: 3049 ----------VSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVS 3098 Query: 385 ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVVPQQITHT 441 +T P T+ S + T TS VT T + + T++ TS+ +T T Sbjct: 3099 TGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDT 3158 Query: 442 SPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLA 500 S D P + +S A+P V + + + P L PS+ Sbjct: 3159 SSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATP------LHVTSPSSASTG 3212 Query: 501 AHTYTPI--TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI 558 T P+ TSSVST P+ +SA T T L + + A + Sbjct: 3213 DTTPVPVTDTSSVSTGHATPLPVTGLSSAST-------GDTTRLPVTDISSASTGQATPL 3265 Query: 559 QGIQPAPISTQGIQPAPIGTPG------IQPAPLGTQGIHS---ATPINTQGLQPAPMGT 609 + +ST P P+ +P P P+ + S ATP+ A G Sbjct: 3266 PVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGH 3325 Query: 610 QQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQ-THSQSAST----NAPAQG- 663 P P TS+ D + P+++P SA+ TT + T SAST P G Sbjct: 3326 TTPLPVTDTSSASTGDTTPL---PVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGA 3382 Query: 664 SSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHV 723 SS P TD +V P P V S ++G P S Sbjct: 3383 SSASTGHATPLPVTDTSSVSTGHATPLP-------VTSLSSVSTGDTTPLPVTDASSAST 3435 Query: 724 SMATPVTVSMETVSNQNNDQPTIAVPPTA-----QQPPPTIPTMIAAASPPSQPAVALST 778 ATP+ V+ + + + P + ++ P P T A+ ++ V ++ Sbjct: 3436 GQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTS 3495 Query: 779 IPGAVPITP-PITTIAA-----APPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPV 832 TP P+T++++ P VT S+S+ P+P PV Sbjct: 3496 SASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPV 3555 Query: 833 SAVPPLATNTVSP-SLALLANNLSMPTSDLP 862 + +T +P + + +++ S T+ LP Sbjct: 3556 TDTSSASTGQATPLPVTIPSSSSSGHTTPLP 3586 Score = 95.5 bits (236), Expect = 2e-19 Identities = 182/815 (22%), Positives = 287/815 (35%), Gaps = 114/815 (13%) Query: 143 PPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNL 201 PP P++ S + T +L P G+ T + I A+ +PV S GH + L Sbjct: 936 PPTPPSITSTGLTSPQTETHTLSPSGSGKTFTT--ALISNATPLPVTYASSASTGHTTPL 993 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTS-------- 253 H ++V P + H S+ T L TS Sbjct: 994 HVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGD 1053 Query: 254 --QLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSAT--RAQSPVITTTAAH 309 LP T+ + H+ P+ S +T + P V T SA+ A S +T T++ Sbjct: 1054 STPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSV 1113 Query: 310 ATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIF 369 +T P + + + V+T T P H T A Sbjct: 1114 STGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHV----------TDASSAST 1163 Query: 370 STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHAT-------- 421 TP+ +++ + +T P T+ S + T T +VT T + + HAT Sbjct: 1164 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDAS 1223 Query: 422 AVTT---SNIPVAKVVPQQITHTSPRIQPDYPA----ERSSLI-----PISGHRASPNPV 469 +V+T +++PV HT+P D + + +SL+ +S +P PV Sbjct: 1224 SVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPV 1283 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQAPNSA 527 + + P L PS+ T P+T SS ST P+ +P+SA Sbjct: 1284 TSTSSASTGHVTP------LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA 1337 Query: 528 ITAQ------TGVGVASTVHLNPMQLMTVDASHARHIQGIQPAP------ISTQGIQPAP 575 T T ST H P+ + DAS A Q P P +ST P P Sbjct: 1338 STGDTTPLPVTDASSVSTGHTTPLHV--TDASSASTGQA-TPLPVTSLSSVSTGDTTPLP 1394 Query: 576 IGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPIS 635 + +P + ATP+ A G P P S+ V D AT + P++ Sbjct: 1395 VTSP-------SSASTGHATPLLVTDTSSASTGHATPLPVTDASS-VSTDHATSL--PVT 1444 Query: 636 NPFSAAPAATTVVQ-THSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDV 694 P +A+ TT + T + SAST S+L TD +V P P Sbjct: 1445 IPSAASTGHTTPLPVTDTSSASTGQAT-------SLL----VTDTSSVSTGDTTPLP--- 1490 Query: 695 ASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 754 V S+ +++G P S ATP+ V+ + ++ + P P++ Sbjct: 1491 ----VTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAS 1546 Query: 755 PPPTIPTMIAAAS----------PPSQPAVALSTIPGAVPITPPITTIAA-APPPSVTVG 803 T P + AS P + P+ A + +P+T + P VT Sbjct: 1547 TGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSP 1606 Query: 804 GSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT------NTVSPSLALLANNLSMP 857 S S+ P+P PV+ L+T + SPS A + +P Sbjct: 1607 SSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLP 1666 Query: 858 TSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTD 892 + ++ P + S D TD Sbjct: 1667 VTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTD 1701 Score = 90.5 bits (223), Expect = 8e-18 Identities = 195/854 (22%), Positives = 310/854 (36%), Gaps = 148/854 (17%) Query: 39 STG-LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 STG ++ P +S S G P V D S + + ++ +SS+ + PV Sbjct: 1066 STGHVTPLPVTSLSSASTGDTTPLP-VTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVT 1124 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAP-------PAHLTPAVPLSFSEGLMKPPPKPTMP 150 ST HA ++ PV T+ P H+T A S S G P P ++ Sbjct: 1125 -----DTSSASTGHA--TSLPVTDTSSVSTGHTTPLHVTDAS--SASTGQATPLPVTSLS 1175 Query: 151 S------RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 S P+ PS+ S P VT T +S A+ +PV S + H Sbjct: 1176 SVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSV-----STDHA 1230 Query: 205 MTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 + V + S PL + + A +++ + + T+ LP +T+ + Sbjct: 1231 TSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1290 Query: 265 VQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS---PVIT----------------- 304 H+ + S +T +A P V + SA+ + PV + Sbjct: 1291 TGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDA 1350 Query: 305 -------TTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALG--T 355 TT H TD++ + Q P S+ + +T PS + G T Sbjct: 1351 SSVSTGHTTPLHVTDASSASTG---QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 1407 Query: 356 PKQQLHTMAQKTIFSTGTPVA-AATVAPILATN---TIPSATTAGSVSHTQAPTSTIVTM 411 P T + T +T PV A++V+ AT+ TIPSA + G HT T VT Sbjct: 1408 PLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG---HT---TPLPVTD 1461 Query: 412 TVPSHSSHATAVT---TSNIPVAKVVPQQITHTSP----RIQPDYPAERSSLIPISGHRA 464 T + + AT++ TS++ P +T TS + P + SS +GH A Sbjct: 1462 TSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAS--TGH-A 1518 Query: 465 SPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQ 522 +P PV + + ++P LP PS+ T P+T SSVST P+ Sbjct: 1519 TPLPVTSLSSASTGDTMP------LPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVT 1572 Query: 523 APNSAITAQT------GVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI------STQG 570 +P+SA T T AS P+ + + ++ H P P+ ST Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTT---PLPVTDTSSASTGD 1629 Query: 571 IQPAPI----------GTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSA 620 P P+ TP +P H ATP+ A G P P S+ Sbjct: 1630 TTPLPVTNASSLSTGHATPLHVTSPSSASTGH-ATPLPVTSTSSASTGHATPLPVTGLSS 1688 Query: 621 VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGM 680 D + +S+ + V S S P +SP A+ G Sbjct: 1689 ATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSP-------SSASTGH 1741 Query: 681 AVRKTLIPPQPPDVASPRVESSMRSTS-GSPRPAGAKPKSEIHVSMATPVTVSMETVSNQ 739 ASP + + S S G P S + + ATP+ V+ +S+ Sbjct: 1742 --------------ASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVT--GLSSA 1785 Query: 740 NNDQPT------IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIA 793 + D T ++ T Q P + + +A++ + P L + T T++ Sbjct: 1786 STDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTP---LPVTDASSASTGDTTSLP 1842 Query: 794 AAPPPSVTVGGSLS 807 P S + G + S Sbjct: 1843 VTIPSSASSGHTTS 1856 Score = 82.4 bits (202), Expect = 2e-15 Identities = 211/997 (21%), Positives = 342/997 (34%), Gaps = 218/997 (21%) Query: 64 VNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVR-----------PYPQVQMLSTHHA 112 V D S + + H++ +SSL + + PV P +ST HA Sbjct: 2099 VTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHA 2158 Query: 113 VASATPVAVTAPPAHLTPAVPL----SFSEGLMKPPP------KPTMPSRPIAPAPPSTL 162 + +A H T ++P+ S S G P P T + P+ PS+ Sbjct: 2159 TSLPVTDTSSASTGHAT-SLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSA 2217 Query: 163 SLPPKVPGQVTVTMESSIPQASAIPVATISG-----------------QQGHPSNLHHIM 205 S +P VT T +S QA+ +PV ++S GH ++L Sbjct: 2218 STGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTS 2277 Query: 206 TTNVQMS----------IIRSNAPGPPLHI-GASHLPRGAA----AAAVMSSSKVTTVLR 250 ++V S PLH+ AS G A ++ S+S T Sbjct: 2278 LSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPL 2337 Query: 251 PTSQLPNAATAQPAVQHIIHQ-----------PIQSRPPVTTSNAIP-PAVVATVSATRA 298 P + +A+T H+ P+ S ++ + P P A+ ++T Sbjct: 2338 PVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGD 2397 Query: 299 QSPV-ITTTAAHATDSALSRPT-------------LSIQHPPSAAISIQRPAQSRDVTTR 344 +P+ +T T++ +T A P L + + SA+ P ++ Sbjct: 2398 TTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSA 2457 Query: 345 ITLPSHPALGTPKQQLHT-------MAQKTIFSTG--------TPVAAAT--VAPILATN 387 T + P GT + T + + STG +P +A+T P+ T+ Sbjct: 2458 STGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTD 2517 Query: 388 TIPSATT----------AGSVSHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVV 434 T PSA+T A S+S T+ TS VT + + HAT++ TS Sbjct: 2518 T-PSASTGDTTPLPVTNASSLS-TRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHAT 2575 Query: 435 PQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYP 493 P +T TS D P + S +A+P PV + + + P LP Sbjct: 2576 PLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTP------LPVTD 2629 Query: 494 PSAYPLAAHTYTPI--TSSVSTIRQYPVSAQAPNSAITAQTG------------------ 533 S+ T P+ TSSVST P+ +P+SA T T Sbjct: 2630 TSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSL 2689 Query: 534 --------------------VGVASTVHLNPMQL---MTVDASHARHIQGIQPAPISTQG 570 AS+ H P+ + +V HA + + +ST Sbjct: 2690 PVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGH 2749 Query: 571 IQPAP------IGTPGIQPAP---LGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAV 621 P P + T P P L + TP+ A G P P S+V Sbjct: 2750 ATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSV 2809 Query: 622 VLADGATIVANPISNPFSAAPA-ATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGM 680 D + P+++ SA+ AT++ T + SAST ++P P +T Sbjct: 2810 STGDTTPL---PVTDTSSASTGHATSLPVTDTSSASTG----HATPLPDTDTSSASTG-- 2860 Query: 681 AVRKTLIPPQPPDVAS-------PRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSM 733 TL+P AS P ++S ST G P S ATP+ V+ Sbjct: 2861 --HATLLPVTDTSSASIGHATSLPVTDTSSIST-GHATPLHVTSPSSASTGHATPLPVTD 2917 Query: 734 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQ------PAVALSTIPGAVPITP 787 + ++ + P P++ P + S S P +LS++ T Sbjct: 2918 TSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVS-----TG 2972 Query: 788 PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 847 T + P S + G + P+P PV++ +T +P Sbjct: 2973 DTTPLPVTSPSSASTGHT------TPLPVTDTSSASTGQATALPVTSTSSASTGDTTP-- 3024 Query: 848 ALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGD 884 +P +D ++ + P + S GD Sbjct: 3025 --------LPVTDTSSASTGQATPLPVTSLSSVSTGD 3053 Score = 79.3 bits (194), Expect = 2e-14 Identities = 191/914 (20%), Positives = 312/914 (34%), Gaps = 137/914 (14%) Query: 50 ANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLST 109 A+S S G P V D S + + ++ SS + + + PV V ST Sbjct: 1750 ASSASTGQATPLP-VTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVT-----DVSSAST 1803 Query: 110 HHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVP 169 A+ P+ VT+P S S G P P S T SLP +P Sbjct: 1804 GQAI----PLPVTSPS---------SASTGDTTPLPVTDASSASTG----DTTSLPVTIP 1846 Query: 170 GQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP-------- 221 + +S+P A V+T GH ++L + T+ P P Sbjct: 1847 SSASSGHTTSLPVTDASSVST-----GHATSL---LVTDASSVSTGDTTPLPVTDTNSAS 1898 Query: 222 -----PLHI-GASHLPRG-AAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 PLH+ AS + G A + V S S +T T+ LP + + + H P+ Sbjct: 1899 TGDTTPLHVTDASSVSTGHATSLPVTSLSSAST--GDTTPLPVTSPSSASSGHTTPLPVT 1956 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 V T +A V S + + + T A + + + P L + S + Sbjct: 1957 DASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP-LPVTDTSSVSTGQAT 2015 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 P +++ T + P T T TP+ +++ + +T P T Sbjct: 2016 PLPVTSLSSASTGDTTPLPVTDTSSAST-------GQDTPLPVTSLSSVSTGDTTPLPVT 2068 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVVPQQITHTSPRIQPD-YP 450 + S + T T +VT + HAT++ S++ +T S D P Sbjct: 2069 SPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTP 2128 Query: 451 AERSSLIPISGHRASPNPV--AMETRSDNRPSVPVQ--------FQYFLPTYPPSAYPLA 500 +S S +P PV + + S+PV LP S+ Sbjct: 2129 LPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTG 2188 Query: 501 AHTYTPI--TSSVSTIRQYPVSAQAPNSAITAQ----------------------TGVGV 536 T P+ TSS ST + P+ +P+SA T T + Sbjct: 2189 HATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSS 2248 Query: 537 ASTVHLNPMQL---MTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHS 593 AST P+ + +V HA + + +ST P P+ +P + Sbjct: 2249 ASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSP-------SSASTGH 2301 Query: 594 ATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA-ATTVVQTHS 652 ATP++ A G P P S+ D + P+++P SA+ AT + T + Sbjct: 2302 ATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPL---PVTSPSSASTGHATPLHVTDA 2358 Query: 653 QSAST--------NAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMR 704 S ST + + SS + L A+ T +P AS + + Sbjct: 2359 SSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLP 2418 Query: 705 STSGSPRPAGAKPK------SEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPT 758 T S G + S ATP+ V+ + ++ + P ++ T Sbjct: 2419 VTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHT 2478 Query: 759 IPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIK 818 P ++ AS S +P+T P + P + V + S+ G P Sbjct: 2479 TPLLVTDASSVSTGDTT------RLPVTSPSSASTGHTTP-LPVTDTPSASTGDTTP--- 2528 Query: 819 VKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVI 878 P+ +S + + SPS A + S+P +D ++ P Sbjct: 2529 -----LPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTS 2583 Query: 879 STEEGDMMETNSTD 892 S GD TD Sbjct: 2584 SASTGDTTPLPVTD 2597 Score = 63.2 bits (152), Expect = 1e-09 Identities = 194/917 (21%), Positives = 323/917 (35%), Gaps = 127/917 (13%) Query: 47 SQIANSGSAGLINPAATVN-DESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQ 105 S + +GS + AA V D G+ +R +++ + Q R V Sbjct: 281 SSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTR----VS 336 Query: 106 MLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLP 165 ++T + + T V + P+ P+ +S + T PS + PS++S Sbjct: 337 QINTLNTLTPVTTSTVLSSPSGFNPSGTVS----------QETFPSGETTTSSPSSVSNT 386 Query: 166 PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 V +V M +S T G S + ++T + S S A P Sbjct: 387 FLVTSKV-FRMPTSRDSTLGNTEETSLSVSGTISAITSKVST-IWWSDTLSTALSP---- 440 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI 285 +S P+ + A S T RP + ++ P V Q I + TT Sbjct: 441 -SSLPPKISTAFHTQQSEGAETTGRPHER----SSFSPGVS----QEIFTLHETTTW--- 488 Query: 286 PPAVVATVSATRAQSPVITTTAAHATDSALSRPTL----SIQHPPSAAISIQRPAQSRDV 341 P + + T +Q+ + +T+ AT P+ +I PS +I P + Sbjct: 489 PSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTY 548 Query: 342 TTR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILA-TNTIPSATTAGSVS 399 ++ TLP G Q TGT A +P + T I +AT+ S Sbjct: 549 SSHSTTLPKTTGAGAQTQWTQ--------ETGTTGEALLSSPSYSVTQMIKTATSPSSSP 600 Query: 400 HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 TS +T T PS ++H+T +TS P Q HT S+ P+ Sbjct: 601 MLDRHTSQQIT-TAPS-TNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPM 658 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + + P + T S + PS V P P+ AA T+ P + Q P Sbjct: 659 TDTKTVTTPGSSFTASGHSPSEIV------PQDAPTIS--AATTFAPAPTGDGHTTQAPT 710 Query: 520 SA--QAPNS-----------AITAQTGVGVASTVHLNPM----QLMTVDAS--------- 553 +A AP+S +++ + +A++V P Q + AS Sbjct: 711 TALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAM 770 Query: 554 -HARHIQGIQPAPISTQGIQPAPIG--TPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQ 610 H + + A TQ +PA G T A + G TP ++G+ + T+ Sbjct: 771 THTHQAESTE-ASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTR 829 Query: 611 ---QPQPEGKTS---AVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGS 664 P + T+ +L+ A+ A P+S +++ T T S++++ P S Sbjct: 830 FSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQS 889 Query: 665 SPR-PSILRKKPA------------------TDGMAVRKT----LIPPQPPDVASPRVES 701 SP PS ++ A T +A + T +PP PP + S + S Sbjct: 890 SPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTS 949 Query: 702 SMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPT 761 T K + +S ATP+ V+ + ++ + P ++ P Sbjct: 950 PQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPL 1009 Query: 762 MIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKE 821 + + S S T P V T +T P P VT S S+ P+P Sbjct: 1010 PVTSPSSVSTG----HTTPLPVTDTSSESTGHVTPLP-VTSFSSASTGDSTPLPVTDTSS 1064 Query: 822 EVEPMDIMRPVSAVPPLATNTVSP------SLALLANNLSMPTSDLPPGASPRKKPRKQQ 875 PV+++ +T +P S A + S+P +D ++ P Sbjct: 1065 ASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVT 1124 Query: 876 HVISTEEGDMMETNSTD 892 S G TD Sbjct: 1125 DTSSASTGHATSLPVTD 1141 Score = 60.8 bits (146), Expect = 7e-09 Identities = 115/497 (23%), Positives = 174/497 (35%), Gaps = 73/497 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 P TGLS A S G P V D S + + ++ +SS + + + PV Sbjct: 3746 PVTGLSSA--------STGDTTPLP-VTDTSSASTRHATPLPVTDTSSASTDDTTRLPVT 3796 Query: 98 VRPYPQVQMLSTHHAV---ASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V ST HA ++T A T L S S G P + S Sbjct: 3797 -----DVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSAST 3851 Query: 155 APAPP------STLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN 208 A P S++S P VT T S A+ +PV + S ++ H Sbjct: 3852 GHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSS-----ASTGHATPVP 3906 Query: 209 VQMSIIRSNAPGPPLHI-GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQH 267 V + S PL + AS L G A ++S + TS LP + + H Sbjct: 3907 VTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSAS-RGDTSTLPVTDASSASTGH 3965 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPS 327 P+ S V+T + P V T SA+ Q+ + T+ + + + P Sbjct: 3966 ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPL-------- 4017 Query: 328 AAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN 387 +T+PS + G T A GTP+ + + + Sbjct: 4018 ----------------PVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGD 4061 Query: 388 TIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP 447 T P T S + T T VT T + + HAT +PV + H +P Sbjct: 4062 TTPLPVTDTSSASTGHATPLPVTDTSSASTGHATP-----LPVTSLSSVSTGHATPLAVS 4116 Query: 448 DYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPI 507 A +S + +S +P+ MET PS+ T PP P + T I Sbjct: 4117 S--ATSASTV------SSDSPLKMETPGMTTPSLKTDGGRRTATSPP---PTTSQT---I 4162 Query: 508 TSSVSTIRQYPVSAQAP 524 S++ + + S AP Sbjct: 4163 ISTIPSTAMHTRSTAAP 4179 Score = 45.4 bits (106), Expect = 3e-04 Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 27/212 (12%) Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 + S TT T L T+ +H +++ PP + + P +V T+ T S Sbjct: 79 TKSTETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMT---S 135 Query: 301 PVITTTAAHATDSAL------SRPTLSIQHPPSAAISIQ--RPAQSRDVTTRITLPSHPA 352 IT T + TDS L S P ++A+SI + QSR + R ++ A Sbjct: 136 KTITMTTS--TDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSA 193 Query: 353 LG----------TPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGS----V 398 T + Q T+ +T + + V ++ T PS TA S V Sbjct: 194 SSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSV 253 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPV 430 ++T TS +T+T + S+ TS++PV Sbjct: 254 TNTSMMTSEKITVTTSTGSTLGNPGETSSVPV 285 Score = 35.8 bits (81), Expect = 0.23 Identities = 73/295 (24%), Positives = 109/295 (36%), Gaps = 42/295 (14%) Query: 39 STG-LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 STG + P +S S G P N S + H++S SS + PV Sbjct: 3898 STGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPL-HVTSPSSASRGDTSTLPVT 3956 Query: 98 ---------VRPYPQVQMLSTHHAVASATPVAVTAPPAHLT-PAVPL------SFSEGLM 141 P P + S + TP+ VT + T A PL S S G Sbjct: 3957 DASSASTGHATPLPLTSLSSV--STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT 4014 Query: 142 KPPPKPTMPSR---------PIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-TI 191 P P T+PS P+ A S++S P VT T +S + +PV T Sbjct: 4015 TPLPV-TIPSSASSGHTTSLPVTDA--SSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071 Query: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGA-SHLPRGAAAAAVMSSSKVTTVLR 250 S GH + L T++ S PL + + S + G A +SS+ + + Sbjct: 4072 SASTGHATPLPVTDTSSA------STGHATPLPVTSLSSVSTGHATPLAVSSATSASTVS 4125 Query: 251 PTSQLP--NAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVI 303 S L P+++ + + PP TTS I + +T TR+ + I Sbjct: 4126 SDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPI 4180 Score = 35.4 bits (80), Expect = 0.29 Identities = 59/268 (22%), Positives = 92/268 (34%), Gaps = 20/268 (7%) Query: 508 TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIS 567 T++ S +SA + N + A T L M T+ +S + H + Sbjct: 59 TAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSPSVH---------N 109 Query: 568 TQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGA 627 P T + T + S T T T++ G S+ + Sbjct: 110 VMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAV 169 Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLI 687 +I A + TT +T Q T+A +Q R + ++ T + R T Sbjct: 170 SITAG------QEGQSRTTSWRTSIQD--TSASSQNHWTRSTQTTRESQTSTLTHRTTST 221 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATP--VTVSMETVSNQNNDQPT 745 P P V + S + TS S A + S + SM T +TV+ T S N T Sbjct: 222 PSFSPSVHNVTGTVSQK-TSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGET 280 Query: 746 IAVPPTAQQPPPTIPTMIAAASPPSQPA 773 +VP T P T ++ PA Sbjct: 281 SSVPVTGSLMPVTSAALVTFDPEGQSPA 308 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 99.8 bits (247), Expect = 1e-20 Identities = 212/901 (23%), Positives = 329/901 (36%), Gaps = 119/901 (13%) Query: 3 PPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAA 62 P P+AG + G +S + P P++G + N+ + +P Sbjct: 71 PESAPRAGPTRSAG-----------TSSRNPASRPPASGRGERAPPAKNTSPGPVSSP-- 117 Query: 63 TVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVT 122 GR S + + S EE P+ LS ++ P T Sbjct: 118 ------GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171 Query: 123 APPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQ 182 PA + GL P P P+ RP P ++S + T E S P Sbjct: 172 PSPAMARRSRAAGTEVGL--PRPAPSARPRPPTEGPRKSVSSASEHS-----TTEPS-PA 223 Query: 183 ASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSS 242 A P A G P++ + S RS GP A PR A A Sbjct: 224 ARRRPSA--GGGLQRPASRSLSSSATPLSSPARS---GP----SARGTPR-APAHPSQPK 273 Query: 243 SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPV-TTSNAIPPA--VVATVSATRAQ 299 K LRP P A PA+ + P+ + P T + +PP + AT Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333 Query: 300 SPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGT--PK 357 SP + T A S + P+L P A P+Q+ T + + P+L T P Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPAT----PPSQAPPSMTTPPMQAPPSLQTIPPI 389 Query: 358 QQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH-TQAPTSTIVTMTVPSH 416 Q H++ ++ + +P+A +++ AT ++ S T + S T +P T ++T PS Sbjct: 390 QVPHSLTSPSLQAPPSPLALSSLQ---ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446 Query: 417 SSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 A P +P P P ++SL P +SP + Sbjct: 447 P-------------ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH------ 487 Query: 477 NRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 P+Q L ++ P A PL++ P+ + S P S Q P +++T + Sbjct: 488 -----PLQALSSLASHSPQA-PLSSLIMPPLETQSSLA---PPSLQTPPASLTTPPLENL 538 Query: 537 ASTVHLNPMQLMTVDASHAR-HIQGIQ-PAPISTQGIQPAPIGTPGIQ-PAPLGTQGIHS 593 S L P L T A H++ PAP Q P+P+ TP + P+ + T + Sbjct: 539 PS---LAPPPLQTASAPLTTPHLETPPCPAPCPLQA-PPSPLTTPPPETPSSIATPPPQA 594 Query: 594 ATPINTQGLQP------APMGTQQPQPEGKTSAVVLADGATIVANPISNPFSA-APAATT 646 + + LQ +P+ T PQ + L + A+P +P + +P A Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654 Query: 647 VVQTHSQSASTNAP---------AQGSSP--RPSILRKKPATDGMAVRKTLIPPQPPDVA 695 + H A + P + +SP PS A +A +PP PP A Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP--A 712 Query: 696 SPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSME-TVSNQNNDQPTIAVPP--TA 752 SP + S +P P A P + V + P + M + + P +A PP Sbjct: 713 SPPMSPSATPPPQAPPPLAAPP---LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769 Query: 753 QQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAP-PPSVTVGGSLSSVLG 811 PP ++P M A PP Q AL+T P +PP + AP PS ++ S + Sbjct: 770 PSPPASLP-MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828 Query: 812 PPVPEIKVKE--EVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSM---PTSDLPPGAS 866 P P + +V P P + P T P ++ L++ P PP S Sbjct: 829 PQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887 Query: 867 P 867 P Sbjct: 888 P 888 Score = 87.4 bits (215), Expect = 7e-17 Identities = 176/778 (22%), Positives = 266/778 (34%), Gaps = 81/778 (10%) Query: 52 SGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV-----VVRPYPQVQM 106 S GL PA+ S AR S+ + ++ +P +RP PQV Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTP 287 Query: 107 LSTHHAVA----SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTL 162 A A S++P+A +P T A P+ + P P PS P+A P Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSG--TKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345 Query: 163 SLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSN--APG 220 P P T+ + P + A P T Q PS L I V S+ + AP Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS-LQTIPPIQVPHSLTSPSLQAPP 404 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVT 280 PL + + + + ++ T+ +Q + ++PA P S PP+ Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA-----STPPDS-PPLQ 458 Query: 281 TSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRD 340 ++P + S + A SP+ + H + S + S Q P S+ I QS Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSL 518 Query: 341 VTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH 400 + P P + L ++A + + P+ P L T P+ Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT----PHLETPPCPAPCPL----- 569 Query: 401 TQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP--DYPAERSSLIP 458 QAP S + T + SS AT + P A P SP + P P + + Sbjct: 570 -QAPPSPLTTPPPETPSSIATPPPQA--PPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626 Query: 459 ISGHRASPNPVA------METRSDNRPSVP----VQFQYFLPTYPPSAYPLAAHTYTPIT 508 + +A P+P A + T S P+ +Q + P PP P + P++ Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686 Query: 509 SSVSTIRQYPVSAQAPNSAIT----AQTGVGVAST--------VHLNPMQLMTVDASHAR 556 S + Q P S AP + A + ++T + P+Q+ + Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746 Query: 557 HIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEG 616 P P + P+ P PA L + P L P+ P Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806 Query: 617 KTSAVVLADGATIVANPISNPFSAAP---AATTVVQTHSQSASTNAPAQGSSPRPSILRK 673 + A++ +P++ P AP AA + S AS A P P Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG---- 862 Query: 674 KPATDGMAVRKTL-IPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVS 732 P T R TL + P PP P S ST P AG H S AT Sbjct: 863 -PDTSVSGPRLTLALAPGPP----PPPSRSPSSTLSGPDLAG-------HSSSATSTPEE 910 Query: 733 METVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT 790 + + + PP A+ AA S P +A PGA PP T Sbjct: 911 LRGYDSGPEGGAAASPPPDAE----LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 964 Score = 62.0 bits (149), Expect = 3e-09 Identities = 143/655 (21%), Positives = 215/655 (32%), Gaps = 83/655 (12%) Query: 225 IGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNA 284 IG + +P A A S+ T+ P S+ P + + A PP ++ Sbjct: 65 IGGATIPESAPRAGPTRSAG-TSSRNPASRPPASGRGERA------------PPAKNTSP 111 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTR 344 P + S T P+ + + ++R + + P +A+S RD Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSA---GARRDT--- 164 Query: 345 ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAP 404 S P GTP + ++ G P A + P T + ++ S T P Sbjct: 165 ----SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220 Query: 405 T-------STIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLI 457 + S + P+ S +++ T + P + S R P PA S Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR-------SGPSARGTPRAPAHPSQPK 273 Query: 458 PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQY 517 P G +A P R D P++ P S+ PLA T S S + Sbjct: 274 P-KGLQALRPPQVTPPRKDAAPALG----------PLSSSPLA-------TPSPSGTKAR 315 Query: 518 PVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 PV P++A T S P+ L S +Q + P + P + Sbjct: 316 PVPP--PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT 373 Query: 578 TPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNP 637 TP +Q P + + PI +P P P +S T + +P Sbjct: 374 TPPMQAPP----SLQTIPPIQVPHSLTSPSLQAPPSPLALSSL----QATTSLGSP---- 421 Query: 638 FSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASP 697 T+ THS + Q S PS P +P PP S Sbjct: 422 --------TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473 Query: 698 RVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPP 757 S S+ + P A H A ++ M + Q++ P P A P Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533 Query: 758 TIPTMIAAASPPSQPAVALSTIPG-AVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPE 816 + + + A PP Q A A T P P P + A P P T S + P P+ Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593 Query: 817 IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKP 871 P+ + P + PLAT L L P S P ASP P Sbjct: 594 APPALASPPLQGL-PSPPLSPLATPPPQAPPXLALPPLQAPPS---PPASPPLSP 644 Score = 60.1 bits (144), Expect = 1e-08 Identities = 86/392 (21%), Positives = 139/392 (35%), Gaps = 38/392 (9%) Query: 490 PTYPPSAYPLAAHTY--------TPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVH 541 P PP P A P+ I + AP + T G + Sbjct: 33 PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPAS 92 Query: 542 LNPMQLMTVDASHARHIQGIQPAPISTQG-----IQPAPIGTPGIQPAPLGTQGIHSATP 596 P A A++ P P+S+ G +P P+G G++ + T AT Sbjct: 93 RPPASGRGERAPPAKNTS---PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149 Query: 597 INTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAS 656 + A P T + +A + + P AP+A T S Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKS 208 Query: 657 TNAPAQGSSPRPS-ILRKKPATDGMAVR---KTLIPPQPPDVASPRVESSMRSTSGSP-R 711 ++ ++ S+ PS R++P+ G R ++L P + R S R T +P Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268 Query: 712 PAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQ 771 P+ KPK + VT + + A+ P + P T A P Sbjct: 269 PSQPKPKG-LQALRPPQVTPPRKDAAP--------ALGPLSSSPLATPSPSGTKARPVPP 319 Query: 772 PAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 831 P A + +P +P +PP+ T PPS + SL ++ PP + P P Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP---PSQAPPSMTTPP 376 Query: 832 VSAVPPLATNTVSPSLALLANNLSMPTSDLPP 863 + A P L T+ P + ++L+ P+ PP Sbjct: 377 MQAPPSL--QTIPP--IQVPHSLTSPSLQAPP 404 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 99.0 bits (245), Expect = 2e-20 Identities = 192/847 (22%), Positives = 306/847 (36%), Gaps = 121/847 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 P++ ++ P NS ++ P T + S S+ M+++S K Sbjct: 1549 PTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSF------KTTTTY 1602 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAPPAH--LTPAVPLSFSEGLMKPPPKPTMPSRPIA 155 P L TH S + V P H +TP + + P T+P Sbjct: 1603 PTPSHPQTTLPTHVPPFSTSLVT---PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTL 1659 Query: 156 PAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNLHHIMTTNVQMSII 214 A ST + P +T+T + S++ A T + H S+ HH T+ + I Sbjct: 1660 KATGSTHTAPT-----MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI 1714 Query: 215 RSNAPG---PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 N PP+ + S + ++ S++K +T L H Sbjct: 1715 TPNPTSTGTPPMTVTTSGTSQSRSS---FSTAKTSTSLHS------------------HT 1753 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 P VT+++ ++ ++T ++PV TT+A T S L P + PP+ Sbjct: 1754 SSTHHPEVTSTSTT--SITPNHTSTGTRTPVAHTTSA--TSSRLPTP-FTTHSPPTGTTP 1808 Query: 332 IQRP----AQSRDVTTRITLPSHPALGTPKQ------QLHTMAQKT-IFSTGTPVAAATV 380 I A S TT PSHP P L T + T I T T +A + Sbjct: 1809 ISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSAS 1868 Query: 381 APILATNTIPSATT--AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPV-------A 431 + T TIP TT A +HT P + + T S SS +TA T++++P Sbjct: 1869 IHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHP 1928 Query: 432 KVVPQQITHTSPRIQPD--------YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 +V P T+ +P+ + SS +P SP P S P Sbjct: 1929 EVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSP-PTGSSPFSSTGPMTAT 1987 Query: 484 QFQ----YFLPTYPPSAYP-----LAAHTYTPITSSV--STIRQYPVSAQ---APNSAIT 529 FQ Y P++P + P + TP T +V +T Q SA P + Sbjct: 1988 SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVP 2047 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPA---PIGTPGIQPA-P 585 T + + H P +T + H A S+ I + P + P+ P Sbjct: 2048 PPTTLKATGSTHTAPPMTVTTSGTSQTH-SSFSTATASSSFISSSSWLPQNSSSRPPSSP 2106 Query: 586 LGTQGIH---SATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANP---ISNPFS 639 + TQ H + TP++T + P +S V + + ++P S+ F Sbjct: 2107 ITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFV 2166 Query: 640 AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRV 699 +AP +T + + S S+ + P S + PA +R TL P ++SP Sbjct: 2167 SAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAA-STTIRATL----PHTISSPFT 2221 Query: 700 ESSM---RSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPP 756 S++ + + SP P+ S I T S T ++ T + P Sbjct: 2222 LSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVP 2281 Query: 757 PT--IPTMIAAASPPSQPAVALST-IPGAVPITPPITTIAAAPPPSVTVGGSLS-----S 808 + + P+ P L+T PG P P T + S+T GS S Sbjct: 2282 TSGFVSLTSGVTGIPTSPVTNLTTRHPG--PTLSPTTRFLTS---SLTAHGSTPASAPVS 2336 Query: 809 VLGPPVP 815 LG P P Sbjct: 2337 SLGTPTP 2343 Score = 93.2 bits (230), Expect = 1e-18 Identities = 166/803 (20%), Positives = 258/803 (32%), Gaps = 98/803 (12%) Query: 138 EGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGH 197 EG+ P PT P P P P+T S P +V P + G Sbjct: 1190 EGVCVPCMPPTTPQPPTTPQLPTTGSRPTQV-----------WPMTGTSTTIGLLSSTGP 1238 Query: 198 PSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPN 257 + +H + Q ++ + + PR A + + T+ L PT+ L + Sbjct: 1239 SPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAV----TPQATSGLPPTATLRS 1294 Query: 258 AATAQPAVQHIIHQPIQSRPPVTTSNA---------IPPAVVATVSATRAQSPVITTTAA 308 AT Q + P TTS A +P + S T +S Sbjct: 1295 TATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGT 1354 Query: 309 HATDSALSRPTLSIQHPPSAAISIQ--RPAQSRDVTTRITLPSHPALGTPKQQLHTMAQK 366 AT + RPT + P+ Q RP + TR T TP+ T + Sbjct: 1355 TATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTT----TEYTTPQTPHTTHSPP 1410 Query: 367 TIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAP-------TSTIVTMTVPSHSSH 419 T S T AT T P+ + + T P T + T+ P+H+ Sbjct: 1411 TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470 Query: 420 ATAVTTSNIPVAKVVPQQI------THTSPRIQPDYPAERSSLIPISGHRASPNPVAMET 473 AT+ + + P + P THT+P I P + S ++ +P + T Sbjct: 1471 ATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNK-TPTSLHSHT 1529 Query: 474 RSDNRPSV-PVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQT 532 S + P V P P P + T TP+ + S S++ P T Sbjct: 1530 SSTHHPEVTPTSTTTITPN------PTSTRTRTPVAHTNSA-----TSSRPPPPFTTHSP 1578 Query: 533 GVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPA---PIGTPGIQPAPLGTQ 589 G + PM + + P P Q P P T + P+ Sbjct: 1579 PTGSSPFSSTGPMTATSFKTTTT------YPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI 1632 Query: 590 GIHSATPINTQGLQPAPMGTQQPQPEGK-TSAVVLADGATIVANPISNPFSAAPAATTVV 648 A + + P GT P K T + A T+ + S S+ A T Sbjct: 1633 TPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTST 1692 Query: 649 QTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSG 708 HS ++ST+ + + T I P P +P + + TS Sbjct: 1693 SLHSHTSSTH-----------------HAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ 1735 Query: 709 SPRP-AGAKPKSEIHVSMAT---PVTVSMETVSNQNNDQPTIAVPPTAQQPPPT---IPT 761 S + AK + +H ++ P S T S N T P A T +PT Sbjct: 1736 SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795 Query: 762 MIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVT----VGGSLSSVLGPPVPEI 817 SPP+ ST P TT P T V +S++ P + Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855 Query: 818 KVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHV 877 + + M +++ + T T+ P + A + + P S + Sbjct: 1856 IIPTHTQ----MATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFST 1911 Query: 878 ISTEEGDMMETNSTDDEKSTAKS 900 T T+ST + T S Sbjct: 1912 AKTSTSLPYHTSSTHHPEVTPTS 1934 Score = 71.6 bits (174), Expect = 4e-12 Identities = 104/486 (21%), Positives = 182/486 (37%), Gaps = 56/486 (11%) Query: 40 TGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVR 99 TG P+ I +GS P SG S+ +S+SL V Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTT--SGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931 Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPA----------HLTPAVPLSFSE-GLMKPPPKPT 148 P + H + + TPVA T + H P FS G M T Sbjct: 1932 PTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT 1991 Query: 149 MPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN 208 + P P+ P T +LP VP T S + ++ + T Q +++H T Sbjct: 1992 TTTYP-TPSHPQT-TLPTHVPPFST----SLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045 Query: 209 VQ----MSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 V + S PP+ + S + ++ + ++S ++ + +S LP ++++P Sbjct: 2046 VPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATAS--SSFISSSSWLPQNSSSRPP 2103 Query: 265 VQHIIHQ---------PIQSRPPVTTSNAIPPAVVATVSA---TRAQSPVITTTAAHATD 312 I Q P+ + +++S + P+ +TVS+ + SP ++ + + Sbjct: 2104 SSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSS 2163 Query: 313 SALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL--HTMAQKTIFS 370 S +S P S + S+ + V+ PS PA T + HT++ S Sbjct: 2164 SFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLS 2223 Query: 371 TGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTT----- 425 P++ TV+P +++ S S T A T T + S +S +T++TT Sbjct: 2224 ALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTS 2283 Query: 426 ---------SNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 + IP + V H P + P SSL + H ++P + + Sbjct: 2284 GFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSL---TAHGSTPASAPVSSLGT 2340 Query: 477 NRPSVP 482 P+ P Sbjct: 2341 PTPTSP 2346 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 97.4 bits (241), Expect = 6e-20 Identities = 195/872 (22%), Positives = 296/872 (33%), Gaps = 135/872 (15%) Query: 117 TPVAVTAPPAHLTPAVPLSFSEGLMKPP------PKPTMPSRPIAPAPPST--LSLPPKV 168 TP AVT P +PA F +G PP PK + + P+ P+T +LP Sbjct: 1010 TPPAVTPPSPKGSPAAT-PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068 Query: 169 PGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGAS 228 G T +++ A P AT +G P+ AP PP S Sbjct: 1069 GGPATPSLKG----APTPPAATPPSPKGGPATPSP------------KGAPMPPAATPPS 1112 Query: 229 HLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPA 288 P+G A + T P S P A P + P + P A PP Sbjct: 1113 --PKGGLATPPHKGAPTTPAATPPS--PKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168 Query: 289 VVA-TVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347 A T A SP AT S PT PPS + P+ TT Sbjct: 1169 KGAPTTPAATPPSP----KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224 Query: 348 PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAG------SVSHT 401 P P G + +P P T P+AT + H Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPIS- 460 AP +VT P ++ P P T SP+ P P + + P + Sbjct: 1285 GAPNPAVVTPPSPKGGP------ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338 Query: 461 ---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQY 517 + +P A S P+ P + PT PP+A P +H P + S R Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEG--PT-PPAATP--SHKGGPAMTPPSPKRGP 1393 Query: 518 PVSA----------------QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGI 561 + + +AP + +T + G S L P + V A Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTRE-GAATPSKGDLTPPAVTPVSLKKAPATSAP 1452 Query: 562 Q--PAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTS 619 + PA S++G P TP P + + +++ PAPMG Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT------LP 1506 Query: 620 AVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDG 679 AV+ + + A P S AP AT + +K PAT Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATL-----------------------LSKKTPAT-- 1541 Query: 680 MAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQ 739 +A ++ LIPP V SP+ ++ + P+ A A P S+ ++P V+ T Sbjct: 1542 LAPKEALIPPAMT-VPSPKKTPAIPT----PKEAPATPSSK---EASSPPAVTPSTYKGA 1593 Query: 740 NNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPS 799 + + + +PP P P A +PPS + P P +PP+T + P Sbjct: 1594 PSPKELL-IPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP- 1651 Query: 800 VTVGGSLSSVLGPPVPEIK--VKEEVEPMDIMRPVSAVPPLATNTV-SPSLALLANNLSM 856 T S++ +G VP+ + + P + + A P +T + +P+ S Sbjct: 1652 -TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSS 1710 Query: 857 PTSDLPPGASPRKKPRKQQHVIST--------EEGDMMETNSTDDEKSTAKSLLVKAEKR 908 TS PP + +ST + D +T D + K L E + Sbjct: 1711 ATS--PPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768 Query: 909 KSPP------KEYIDEEGVRYVPVRPRPPITL 934 S P ++ + + V P PP++L Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800 Score = 90.9 bits (224), Expect = 6e-18 Identities = 162/771 (21%), Positives = 272/771 (35%), Gaps = 100/771 (12%) Query: 92 KQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 K P YP V + + TP+ VT P + A +F PP + P Sbjct: 416 KSSPNATYHYPLVAQMPV--SSVGTTPLVVTNP-CTIAAAPTTTFEVATCVSPPMSSGPI 472 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM 211 I P P+ L + P P + + + +++ + P+ + PS++ T + Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532 Query: 212 SIIRSN---APGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAV--Q 266 + ++ AP P G + V ++ K + + TS P + A + Sbjct: 533 QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAK 592 Query: 267 HIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP 326 + +P+ P ++ + P V ++ S + S +A S+L PT++ Sbjct: 593 KSLGEPLPIGKPASSMTS-PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLE 651 Query: 327 SAAISIQRPAQSRDVTTRITLPSHPALGT----PKQQLHTMAQKTIFSTGTPVAAATVAP 382 SA + P ++ +T T S GT PK H + + T+ T P Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN--HPVKEGTL----------TTLP 699 Query: 383 ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTS 442 ++ T + + A S +T AP +T+V S + ++ + P I+HTS Sbjct: 700 LVPTAS-ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758 Query: 443 PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH 502 + P + + SG A+ + T + PS P+ T P +A Sbjct: 759 A-LAPVASSPKECPTEDSGASATASSKGTLTYLADSPS-PLGVSVSPQTKRPPTKKGSAG 816 Query: 503 TYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ 562 TPI + S + S NS QG + Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSL-----------------------------SFQGSK 847 Query: 563 PAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVV 622 +P +T P P+P G + TP++ +G+ P T P Sbjct: 848 DSPATTHSPTP---------PSPKGAPTPSAVTPLSPKGVTLPPKETPTP---------- 888 Query: 623 LADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQG-SSPRPSILRKKPATDGMA 681 ++V P A PA Q + S ++++P + ++P P + P+ G Sbjct: 889 -----SVVNLPFPKEGPATPAPK---QAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940 Query: 682 VRKTLIPPQP---PDVASPR-VESSMRSTSGSPR--PAGAKPKSEIHVSMATPVTVS--M 733 PP P P SP+ + +T SP+ PA PK ATP + Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000 Query: 734 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIA 793 T S + P PP+ + P P A++PP+ + P A P+ T Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060 Query: 794 AAPPPSVTVGGSLSSVLGPPVPEIKVKEEVE-------PMDIMRPVSAVPP 837 AA PS G + S+ G P P + P P +A PP Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111 Score = 87.4 bits (215), Expect = 7e-17 Identities = 200/861 (23%), Positives = 286/861 (33%), Gaps = 107/861 (12%) Query: 36 GAPSTGLSQAPSQIANSGSAGLIN----PAATVNDESGRDSEVSAREHMSSSSSLQSREE 91 GAP+T + PS + L PAAT G + S + Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG------------A 1102 Query: 92 KQEPVVVRPYPQVQMLSTHHAVASATPVAV---------TAPP--AHLTPAV-PLSFSEG 139 P P P+ + + H A TP A T PP A TPA P S G Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162 Query: 140 LMKPPPK--PTMPSR-PIAP-----------APPSTLSLPPKVPGQVTVTMESSIPQASA 185 L PPPK PT P+ P +P AP + + PP G + P A Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222 Query: 186 IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLP-------RGAAAAA 238 + G PS TT P P GA P +G A Sbjct: 1223 ATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281 Query: 239 VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP-PVTTSNAIPPAVVATVSATR 297 + V+ P S AT+ P + P + P P + PP T A Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPP--KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339 Query: 298 AQSPVITTTAAHATDSALSRPTLSIQH----PPSAAISIQR-PAQSRDVTTRITLPSHPA 352 SP T T T S+ PT PP+A S + PA + R PA Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR-----GPA 1394 Query: 353 LGTPKQQLHTMAQKTIF---STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIV 409 + +PK + A + + TPV A + P A T S+ A ++ Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454 Query: 410 TMTVPSHSSHATA-VTTSNIPVAKVVPQQI-THTSPRIQPDYPAERSSLIPISGHRASPN 467 PS T T P P+Q+ T +SP+ P PA + + +SP Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514 Query: 468 PVAMETRSDNRPSVPVQFQYFLPTYP---------PSAYPLAAHTYTPITSSVSTIRQYP 518 V S P P T P A + + TP + P Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574 Query: 519 VSAQAPNS-AITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 S +A + A+T T G S P +L+ A + + AP P+P Sbjct: 1575 SSKEASSPPAVTPSTYKGAPS-----PKELLIPPAVTS---PSPKEAPTPPAVTPPSPEK 1626 Query: 578 TPGIQPAPLGTQGIHSATPINTQGLQPAP------MGTQQPQPEGKTSAVVLADGATIVA 631 P PAP GT TP + + +P MG PQ + + G T + Sbjct: 1627 GPAT-PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA---SKGLPAKKGPTALK 1682 Query: 632 NPISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ 690 + P + P T + Q+ ++A + P PS L+P Q Sbjct: 1683 EVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742 Query: 691 PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 750 + + + + S G P +K + + + V E+ S P +++P Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP- 1801 Query: 751 TAQQPPPTIPT--MIAAASP------PSQPAVALSTIPGAVPITPPITTIAAAPPPSVTV 802 A P PT+P +SP PS+P +A + +P+ PP P SV V Sbjct: 1802 LAPSPVPTLPPKQQFLPSSPGLVLESPSKP-LAPADEDELLPLIPPEPISGGVPFQSVLV 1860 Query: 803 GGSLSSVLGPPVPEIKVKEEV 823 G PVP K+ V Sbjct: 1861 NMPTPKSAGIPVPTPSAKQPV 1881 Score = 74.7 bits (182), Expect = 4e-13 Identities = 190/826 (23%), Positives = 304/826 (36%), Gaps = 144/826 (17%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 P + PQ Q + ++SA ++VTA P +P S + P + P Sbjct: 10 PATEQELPQPQAETAVLPMSSA--LSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPF 67 Query: 155 APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P+P + S P +VP PQ+S+ + P+ L +++ + + + Sbjct: 68 -PSPSTIASTPLEVP----------FPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAAL 116 Query: 215 RSNAP--GPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPT--SQLPNAATAQPAVQHIIH 270 +P P L S A A S + ++ P + P+ A A+ + Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176 Query: 271 QPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATD--SALSRPTLSI-QHPPS 327 PI P T N +P VV T + +++T H +++ S+ Q P+ Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT 236 Query: 328 AAISIQRPAQSRDVTTRITL--PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILA 385 ++I P Q +D T L P +P + K + A ++ + PV + Sbjct: 237 TTLAIASP-QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS------- 288 Query: 386 TNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH--------ATAVTTSNIPVAKVVPQQ 437 S TAG + P S + + P H S T + + P K + Sbjct: 289 -----SQKTAGPNTPPDFPIS-LGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI--S 340 Query: 438 ITHTSPRIQPDYPAERSSLIPI-SGHRASPNPVA----METRSDNRPSVPVQFQYFLPTY 492 + H+S YP++RS + P+ S + P VA + D PS T Sbjct: 341 VDHSSTGAS--YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSI-----TC 393 Query: 493 PPS-------AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 PS ++ L+ T + SS + YP+ AQ P S+ VG V NP Sbjct: 394 SPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSS------VGTTPLVVTNPC 447 Query: 546 QLMTVDASHARHIQGIQP----APIST-QGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 + + + P PIS + PA + + P TQ AT + Sbjct: 448 TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQ---VATTLRI- 503 Query: 601 GLQPAPMGTQQPQPE---GKTSAVVLA-----DGATIVANPISNPFSAAPAATTVVQTHS 652 P+ P PE S+V++ D T+ A+ PFS A A T + + Sbjct: 504 -----PVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPT 558 Query: 653 -----QSASTNAPA-QGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRST 706 Q+A N+P+ Q +S P I AT +K+L Sbjct: 559 VLPLVQAAPKNSPSFQSTSSSPEIPLSPEAT---LAKKSL-------------------- 595 Query: 707 SGSPRPAGAKPKSEIHVSMATPVTV--SMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIA 764 G P P G KP S SM +P+ V S + + P A P + PT+ A Sbjct: 596 -GEPLPIG-KPAS----SMTSPLGVNSSASVIKTDSYAGPDSAGP--LLKSSLITPTVAA 647 Query: 765 AASPPSQPA-VALSTIPGAVPITPPIT-----TIAAAPPPSVTVGGSLSSVLGPPVPEIK 818 + PA VA +T G T + T++ AP G+L+++ P VP Sbjct: 648 FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTL--PLVPTAS 705 Query: 819 VKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 V P P + PLAT ++P + + S+P + PPG Sbjct: 706 ENCPVAPS----PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747 Score = 42.0 bits (97), Expect = 0.003 Identities = 95/428 (22%), Positives = 150/428 (35%), Gaps = 58/428 (13%) Query: 37 APSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 AP+ L + + LI PA TV + + +E ++ SS +E P Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS----KEASSPP 1583 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 V P ST+ S P + PPA +P S PP T PS P Sbjct: 1584 AVTP-------STYKGAPS--PKELLIPPAVTSP------SPKEAPTPPAVTPPSPEKGP 1628 Query: 157 A-------------PPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHH 203 A PS+L P P VT M +++PQAS + ++G P+ L Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQAS----KGLPAKKG-PTALKE 1683 Query: 204 IMTTNVQMS--II-----------RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLR 250 ++ S II +S+A PP+ S + ++ + + V + Sbjct: 1684 VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743 Query: 251 PTSQLPNAATAQPAVQHIIHQP-IQSRPPVTTS---NAIPPAVVATVSATRAQSPVITTT 306 +S+ A + + + P ++ P+T + +P A+VSA A SP ++ Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA--APSPPVSLP 1801 Query: 307 AAHATDSALSRPTLSIQHPPSAAI-SIQRPAQSRDVTTRITL-PSHPALGTPKQQLHTMA 364 A + L + P + S +P D + L P P G Q + Sbjct: 1802 LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVN 1861 Query: 365 QKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVT 424 T S G PV + + N S T + S T + A A Sbjct: 1862 MPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAE 1921 Query: 425 TSNIPVAK 432 PV+K Sbjct: 1922 IDEEPVSK 1929 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 93.2 bits (230), Expect = 1e-18 Identities = 181/811 (22%), Positives = 287/811 (35%), Gaps = 121/811 (14%) Query: 108 STHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL 164 S+ A+A P T P A A+P S + T P+ ++ A PS S Sbjct: 3216 SSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPS--ST 3273 Query: 165 PPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG---- 220 P V +T ++ +A+ VAT S G TT + S++PG Sbjct: 3274 PETVHTSTVLTTTTTTTRATG-SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3332 Query: 221 PPLHIGASHLP--RGAAA--AAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSR 276 PP+ I + P RG+ +++ ++ TVL T+ AT A Q + Sbjct: 3333 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT--TVATGSMATPSSSTQTSGTP 3390 Query: 277 PPVTTS-------------------NAIPPAVVATVSATRAQSPVITTTAAHATDSALSR 317 P +TT+ IPP + T + A S +T ++A T Sbjct: 3391 PSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 3450 Query: 318 P-TLSIQH----PPSAAISIQRPAQSRDV----TTRITLPSHPALGTPKQQLHTMAQKT- 367 P T + H PPS+ +++ S TT IT PS TP T T Sbjct: 3451 PNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTP 3510 Query: 368 IFSTGTPVAAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVT 424 S+ P + T +P T P T S + T P+ T + +PS + A T V Sbjct: 3511 ALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVV 3570 Query: 425 TSNIPVAKVVPQQITHTSPRIQPDY-PAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 T+ + + ++ P P + S I +G P+ +E R+ +P VP+ Sbjct: 3571 TTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPL 3630 Query: 484 Q----------------------------FQYFL----------PTYP-------PSAYP 498 + F Y + P+ P PS+ P Sbjct: 3631 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTP 3690 Query: 499 LAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ--TGVGVASTVHLNPMQLMTVDASHAR 556 T +T++ +T +A ++ T T +TV + T ++ A Sbjct: 3691 GTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQAT 3750 Query: 557 ----HIQGIQPAPISTQGIQPAPIGTPGIQPA-PLGTQGIHSATPINTQGLQPAPMGTQQ 611 H+ P T + P +PG A P + T + + + +GT Sbjct: 3751 AGTPHVSTTATTPTVTSS-KATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW 3809 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671 + T+ AT P S P +A + + A+ + S+P + Sbjct: 3810 TRLSQTTTPTATMSTAT----PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHT 3865 Query: 672 RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAK-PKSEIHVSMATPVT 730 K P T T+ P P A R ST+ +P +G+ S + + TP Sbjct: 3866 TKVPTTTTTGF--TVTPSSSPGTA--RTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTV 3921 Query: 731 VSMETVSNQNNDQPTIAVPPTAQQPPP---TIPTMIAAASPPSQPAVALSTIPGAVPITP 787 ++ T + T + PP T T I A + P S+ PG PI P Sbjct: 3922 LTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNP----SSTPGTTPIPP 3977 Query: 788 PITTIA---AAPPPSVTVGGSLSSVLGPPVP 815 +TT A AA +VT +L + PPVP Sbjct: 3978 VLTTTATTPAATSSTVTPSSALGTTHTPPVP 4008 Score = 89.0 bits (219), Expect = 2e-17 Identities = 165/726 (22%), Positives = 252/726 (34%), Gaps = 98/726 (13%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTV 174 +++P APPA T AVP + SEGL P T+ + S P VPG T Sbjct: 1637 TSSPGLTRAPPASTT-AVP-TLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVAT- 1693 Query: 175 TMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGA 234 S++P SA+P T S PS + T + S R AS P Sbjct: 1694 ---STLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAST----ASKEPLTT 1746 Query: 235 AAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVT----------TSNA 284 + A + +S+++T TS T P Q P ++ Sbjct: 1747 SLAPTL-TSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSG 1805 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP---SAAISIQRPAQSRDV 341 + + T RA + A + P +SI + ++ ++ D Sbjct: 1806 VAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQ 1865 Query: 342 TTRITL--PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVS 399 T R + + + H + ST TP + IL T +ATT S Sbjct: 1866 TGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWIL-TKPTTTATTTASTG 1924 Query: 400 HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 T PTST+ T P T TT + +K P +SP PA RS+ Sbjct: 1925 STATPTSTL--RTAPPPKVLTTTATTPTVTSSKATPS----SSPGTATALPALRSTATTP 1978 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + +P P + + R S + T PS+ P AHT T +T++ +T Sbjct: 1979 TATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT------ 2032 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A S T + G A T + +T G P +P Sbjct: 2033 -TGATGSVATPSSTPGTAHTTKV---------------------PTTTTTGFTATPSSSP 2070 Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPM---GTQQPQPEGKTSAVVLADGATIVANPISN 636 G P I + T T+G P GT T+ +A G+ + + Sbjct: 2071 GTALTP--PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQ 2128 Query: 637 PFSAAPAATTVVQTHSQSASTNAPAQ--GSSPRPSIL---------RKKPATDGMAVRKT 685 P+ TT T + + ST P+ G++P P +L T A+ T Sbjct: 2129 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTT 2188 Query: 686 LIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEI----HVSMATPVT--VSMETVSNQ 739 PP P +A+ S S+ + R A S I H++ + VT T Sbjct: 2189 HTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTT 2248 Query: 740 NNDQPTIAVP----PTAQQPP---------PTIPTMIAAASPPSQPAVALSTIPGAVPIT 786 + P ++ P T + PP T + A + PS+ ST+ + P + Sbjct: 2249 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK--TRTSTLLPSSPTS 2306 Query: 787 PPITTI 792 PITT+ Sbjct: 2307 APITTV 2312 Score = 85.5 bits (210), Expect = 2e-16 Identities = 196/852 (23%), Positives = 301/852 (35%), Gaps = 170/852 (19%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPA-HLTPAVPLSFSEGLMKPPPKPTM---- 149 P V+ +++ A S++P TA PA T P + S + P P ++ Sbjct: 1939 PKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS---VTPIPSSSLGTTW 1995 Query: 150 -----PSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 + P A +T S P+ TV ++ + VAT S G Sbjct: 1996 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 2055 Query: 205 MTTNVQMSIIRSNAPG----PPLHIGASHLP--RGAAA--AAVMSSSKVTTVLRPTSQLP 256 TT + S++PG PP+ I + P RG+ +++ ++ TVL T+ Sbjct: 2056 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT-- 2113 Query: 257 NAATAQPAVQHIIHQPIQSRPPVTTS-------------------NAIPPAVVATVSATR 297 AT A Q + P +TT+ IPP + T + Sbjct: 2114 TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 2173 Query: 298 AQSPVITTTAAHATDSALSRP-TLSIQH----PPSAAISIQRPAQSRDV----TTRITLP 348 A S +T ++A T P T++ H PPS+ +++ S TT IT P Sbjct: 2174 ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233 Query: 349 SHPALGTPKQQLHTMAQKT-IFSTGTPVAAATVAPILATNTIPSATTAGS-VSHTQAPTS 406 S T T T S+ P + T +P T P TTA S + T P+ Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 2293 Query: 407 TIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPD-YPAERSSLIPISGHR 463 T + +PS + A T V T + + ++ P P + S I +G Sbjct: 2294 TRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGA 2353 Query: 464 ASPNPVAMETRSDNRPSVPVQ----------------------------FQYFL------ 489 P+ +E R+ +P VP++ F Y + Sbjct: 2354 VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCN 2413 Query: 490 ----PTYP-------PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA--QTGVGV 536 P+ P PS+ P T +T++ +T +A ++ T T Sbjct: 2414 YGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPST 2473 Query: 537 ASTVHLNPMQLMTVDASHAR----HIQGIQPAPISTQGIQPAPIGTPGIQ---PAPLGTQ 589 +TV + T ++ A H+ P T + P +PG PA T Sbjct: 2474 TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS-KATPFSSPGTATALPALRSTA 2532 Query: 590 GIHSAT-----PINTQG----------LQPAPMGTQQPQ--PEGKTSAVVLADGATI--- 629 +AT P ++ G A M T P PE ++ VL AT Sbjct: 2533 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGA 2592 Query: 630 ---VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTL 686 VA P S P A TT V T + + T P S P R P + + T Sbjct: 2593 TGSVATPSSTP---GTAHTTKVLTTTTTGFTATP----SSSPGTARTLP----VWISTTT 2641 Query: 687 IPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTI 746 P +P SS+ T+ +P V T TV+ +++ ++ T Sbjct: 2642 TPTTRGSTVTP---SSIPGTTHTPT-----------VLTTTTTTVATGSMATPSSSTQTS 2687 Query: 747 AVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIA---AAPPPSVTVG 803 PP+ T T I A + P S+ PG PI P +TT A AA +VT Sbjct: 2688 GTPPSL----TTTATTITATGSTTNP----SSTPGTTPIPPVLTTTATTPAATSSTVTPS 2739 Query: 804 GSLSSVLGPPVP 815 +L + PPVP Sbjct: 2740 SALGTTHTPPVP 2751 Score = 83.2 bits (204), Expect = 1e-15 Identities = 181/849 (21%), Positives = 286/849 (33%), Gaps = 124/849 (14%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS+ P+ Sbjct: 3779 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST---PETAH 3835 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG----PPLHIG 226 TV ++ + VAT S G TT ++ S++PG PP+ I Sbjct: 3836 TSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIS 3895 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRP--TSQLPNAATAQPAVQHIIHQPIQSRPPVTTS-- 282 + P + + SS TT T+ AT A Q + P + T+ Sbjct: 3896 TTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTAT 3955 Query: 283 -----------------NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP------- 318 IPP + T + A S +T ++A T P Sbjct: 3956 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTH 4015 Query: 319 --TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT-IFSTGTPV 375 +LS P + + TT IT PS TP T T S+ P Sbjct: 4016 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4075 Query: 376 AAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAK 432 + T +P T P TTA S + T P+ T + +PS + A T V T+ Sbjct: 4076 SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQC 4135 Query: 433 VVPQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV-------- 483 + + ++ P P + S I +G P+ +E R+ +P VP+ Sbjct: 4136 AWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVE 4195 Query: 484 ------------------------QFQYFLPTYP--PSAYPLAAHTYTPITSSVSTIRQY 517 + + F Y PS P + T P ++ +T Sbjct: 4196 CSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPST-PATSSTAMPSSTPGTTWILT 4254 Query: 518 PVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 ++ A +A T T ++ P +++T A+ + S + P+ Sbjct: 4255 ELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVL 4314 Query: 578 T--------PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLADGA 627 T + P P T G P T A M T P PE ++ VL A Sbjct: 4315 TSTATKSTATSVTPIPSSTLGTTGTLPEQTT-TPVATMSTIHPSSTPETTHTSTVLTTKA 4373 Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLI 687 T S ++ TT + T +A+T A G + PS P T + T Sbjct: 4374 TTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPS---STPGTTWILTELT-- 4428 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET--VSNQNNDQPT 745 ++ ST + P+ + I +T TV++ T + ++ Q T Sbjct: 4429 ----------TTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQAT 4478 Query: 746 IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG--AVPITPPITTIAAAPPPSV-TV 802 P + T PT+ ++ + PS + +P + TP T+ A P S+ T Sbjct: 4479 AGTPHVS--TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 4536 Query: 803 GGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNL-SMPTSDL 861 LS P M P S + T+TV + A S+ T Sbjct: 4537 WTRLSQTTTP----------TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSS 4586 Query: 862 PPGASPRKK 870 PG + K Sbjct: 4587 TPGTAHTTK 4595 Score = 82.4 bits (202), Expect = 2e-15 Identities = 177/801 (22%), Positives = 278/801 (34%), Gaps = 120/801 (14%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS S P V Sbjct: 2522 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS--STPETVHT 2579 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP----PLHIG 226 +T ++ A+ VAT S G + TT + S++PG P+ I Sbjct: 2580 STVLTTTATTTGATG-SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIS 2638 Query: 227 ASHLP--RGAAA--AAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTT- 281 + P RG+ +++ ++ TVL T+ AT A Q + P +TT Sbjct: 2639 TTTTPTTRGSTVTPSSIPGTTHTPTVL--TTTTTTVATGSMATPSSSTQTSGTPPSLTTT 2696 Query: 282 ------------------SNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP----- 318 + IPP + T + A S +T ++A T P Sbjct: 2697 ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 2756 Query: 319 ----TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT-IFSTGT 373 +LS P + + TT IT PS TP T T S+ Sbjct: 2757 THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH 2816 Query: 374 PVAAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPV 430 P + T +P T P T A S + T P+ T + +PS + A T V T Sbjct: 2817 PSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEP 2876 Query: 431 AKVVPQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQ----- 484 + + ++ P P + S I +G P+ +E R+ +P VP++ Sbjct: 2877 QCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQV 2936 Query: 485 -----------------------FQYFLPTY------PPSAYPLAAHTYTPITSSVSTIR 515 F Y + + PS P + T TP ++ +T Sbjct: 2937 VECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPST-PATSSTATPSSTPGTTWI 2995 Query: 516 QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAP 575 + A +A T T + ++ P +++T A+ + S + P Sbjct: 2996 LTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLP 3055 Query: 576 IGT--------PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLAD 625 + T P P T G P T A M T P PE ++ VL Sbjct: 3056 VLTSTATKSTATSFTPIPSFTLGTTGTLPEQTT-TPMATMSTIHPSSTPETTHTSTVLTT 3114 Query: 626 GATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKT 685 AT S ++ TT + T +A+T A G + PS P T T Sbjct: 3115 KATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPS---STPGT-------T 3164 Query: 686 LIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPT 745 I +P A+ V + +T+ S R K + S AT TV + ++ Sbjct: 3165 WILTEPSTTATVTVPTGSTATASSTRATAGTLK--VLTSTATTPTVISSRATPSSSPGTA 3222 Query: 746 IAVP---PTAQQPPPTIPTMIAAA---------SPPSQPAVALST-IPGAVPITPPITTI 792 A+P TA P T T I ++ S + P +ST P + P T +T+ Sbjct: 3223 TALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTV 3282 Query: 793 AAAPPPSVTVGGSLSSVLGPP 813 + GS+++ P Sbjct: 3283 LTTTTTTTRATGSVATPSSTP 3303 Score = 78.2 bits (191), Expect = 4e-14 Identities = 126/565 (22%), Positives = 197/565 (34%), Gaps = 59/565 (10%) Query: 277 PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPA 336 P V TS A P ++ AT + SP TT T +A S+ PS+ + Sbjct: 4282 PKVLTSPATTPTATSS-KATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTL 4340 Query: 337 QSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPI-------LATNTI 389 + T T+ + TP + HT T +T T ++T P + T Sbjct: 4341 PEQTTTPVATMSTIHPSSTP-ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELT 4399 Query: 390 PSATTAGSVSHTQAPTST---------IVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH 440 +ATT + T P+ST + T + S+ +TA +S ++ + T Sbjct: 4400 TAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTT 4459 Query: 441 TSPRIQPDYPAERSSLIPISG--HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYP 498 + + A SS +G H ++ T S PS LP +A Sbjct: 4460 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATT 4519 Query: 499 LAAHTYTPI-TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 A ++T I +SS+ T P + ++ T TVH + + T + A Sbjct: 4520 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGA-- 4577 Query: 558 IQGIQPAPIS--------------TQGIQPAPIGTPGIQPAP---LGTQGIHSATPINTQ 600 G P S T G P +PG P + T + T T Sbjct: 4578 -TGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTS 4636 Query: 601 GLQPAPM---GTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAST 657 G P GT T+ +A G+ + + P+ TT T + + ST Sbjct: 4637 GSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 4696 Query: 658 NAPAQ--GSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRV--ESSMRSTSGSPRPA 713 P+ G++P +L T K P + V ++ +ST+ S P Sbjct: 4697 TNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPI 4756 Query: 714 GAKPKSEIHVSMATP--VTVSMETVSNQNNDQPTIAVPPTAQQPP--PTIPTMIAAASPP 769 P S + + P T M T+S + T + P T T TM A + Sbjct: 4757 ---PSSTLWTTWTVPAQTTTPMSTMSTIH----TSSTPETTHTSTVLTTTATMTRATNST 4809 Query: 770 SQPAVALSTIPGAVPITPPITTIAA 794 + P+ L T +T TT AA Sbjct: 4810 ATPSSTLGTTRILTELTTTATTTAA 4834 Score = 77.8 bits (190), Expect = 5e-14 Identities = 168/744 (22%), Positives = 254/744 (34%), Gaps = 101/744 (13%) Query: 153 PIAPAPPSTLSLPPKVPGQVTVTME---SSIPQASAIPVATISGQQGHPSNLHHIMTTNV 209 P PA ST ++P PG + E ++ AS AT S G Sbjct: 4232 PSTPATSST-AMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG------------- 4277 Query: 210 QMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHII 269 AP P + + P ++ A SSS T P + +V I Sbjct: 4278 -------TAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIP 4330 Query: 270 HQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPS-- 327 + + + P A ++T+ + T+T T + +R T S P S Sbjct: 4331 SSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL-TTKATTTRATSSTSTPSSTP 4389 Query: 328 AAISIQRPAQSRDVTTRITLPSHPALGTP-----KQQLHTMAQKTIF--STGTPVAAATV 380 I + TT T P+ TP +L T A T ST TP + Sbjct: 4390 GTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGT 4449 Query: 381 APIL------ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVV 434 IL AT T+P+ +TA + S TQA T H S T TT + +K Sbjct: 4450 TWILTEPSTTATVTVPTGSTA-TASSTQATAGT-------PHVS--TTATTPTVTSSKAT 4499 Query: 435 PQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPP 494 P +SP PA RS+ + + P + + R S + T P Sbjct: 4500 PS----SSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATP 4555 Query: 495 SAYPLAAHTYTPITSSVST---IRQYPVSAQAPNSAITAQ----TGVGVASTVHLNPMQL 547 S+ P HT T +T++ +T + P +A T + T G +T +P Sbjct: 4556 SSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 4615 Query: 548 MTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPM 607 +T + P +T G P PG + + + T G P Sbjct: 4616 LTPPVWISTTTTPTTTTP-TTSGSTVTPSSIPGTTHT---ARVLTTTTTTVATGSMATPS 4671 Query: 608 GTQQ----PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPA-Q 662 + Q P T+ + A G+T NP S P P + T + A+T++ A Sbjct: 4672 SSTQTSGTPPSLTTTATTITATGST--TNPSSTP-GTTPITPVLTSTATTPAATSSKATS 4728 Query: 663 GSSPRPSI---LRKKPATDGMAVRKTLIPPQ--------PPDVASPRVESSMRSTSGSPR 711 SSPR + + AT A T IP P +P S TS +P Sbjct: 4729 SSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPE 4788 Query: 712 PAGAKPKSEIHVSMATPVTVSMETVSNQN-NDQPTIAVPPTAQQPPPTIPTMIAAASPPS 770 H S T +M +N T+ + T T A S Sbjct: 4789 TT--------HTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGS--- 4837 Query: 771 QPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMR 830 LS+ PG I +TIA P+ + + S++ P++ P Sbjct: 4838 --TATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMP---TA 4892 Query: 831 PVSAVPPLATNTVSPSLALLANNL 854 S VP +T + + A+L ++L Sbjct: 4893 TASTVPSSSTVGTTRTPAVLPSSL 4916 Score = 76.3 bits (186), Expect = 2e-13 Identities = 129/584 (22%), Positives = 207/584 (35%), Gaps = 76/584 (13%) Query: 274 QSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQ 333 Q+ TT+ A+ ++ T V+T+TA T ++ S+ T S + + + Sbjct: 2999 QTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS-SKATSSSSPRTATTLPVL 3057 Query: 334 RPAQSRDVTTRITLPSHPALGT----PKQQLHTMA-QKTIFSTGTPVAAATVAPILATNT 388 ++ T T LGT P+Q MA TI + TP T + +L T Sbjct: 3058 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHT-STVLTT-- 3114 Query: 389 IPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH---TSPRI 445 ATT + S P+ST T + + + A T + P A T T P Sbjct: 3115 --KATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPST 3172 Query: 446 QPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT 505 S S RA+ + + T + P+V + + + P +A L A T Sbjct: 3173 TATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRST 3231 Query: 506 PITSSVSTIRQYPVSA-----------QAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 T + +++ P S+ P + ++ T TVH + + T + Sbjct: 3232 ATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3291 Query: 555 ARHIQGIQPAPISTQG----IQPAPIGTPGIQPAPLGTQG--------IHSATPINTQGL 602 A G P ST G + T G P + G I + T T+G Sbjct: 3292 A---TGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGS 3348 Query: 603 QPAPM---GTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNA 659 P GT T+ +A G+ + + P+ TT T + + ST Sbjct: 3349 TVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN 3408 Query: 660 PAQ--GSSPRPSIL---------RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSG 708 P+ G++P P +L T A+ T PP P A+ S S+ Sbjct: 3409 PSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPH 3468 Query: 709 SPRPAGAKPKSEI----HVSMATPVT--VSMETVSNQNNDQPTIAVP----PTAQQPPP- 757 + R A S I H++ + VT T S + P ++ P T + PP Sbjct: 3469 TVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSP 3528 Query: 758 ----------TIPTMIAAASPPSQPAVALSTIPGAVPITPPITT 791 T T A ++ + L + P + PIT +TT Sbjct: 3529 GTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 3572 Score = 72.4 bits (176), Expect = 2e-12 Identities = 141/611 (23%), Positives = 207/611 (33%), Gaps = 85/611 (13%) Query: 231 PRGAAAAAVMSSSKVTTVL--RPTSQLPNAATAQPAVQHIIHQPIQSRPP-VTTSNAIPP 287 P ++ A S+ T +L + T+ A T A+ P + PP V TS A P Sbjct: 2978 PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPS--STPGTAPPPKVLTSTATTP 3035 Query: 288 AVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347 ++ AT + SP TT T +A S PS + + T T+ Sbjct: 3036 TATSS-KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094 Query: 348 PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNT---IPSATTAGSVSHTQAP 404 + TP + HT T +T T ++ P T + TTA + + P Sbjct: 3095 STIHPSSTP-ETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP 3153 Query: 405 TSTIVTMTVPSHSSHATAVTTSNIPVAKV-VPQQITHTSPRIQPDYPAERSSLIPISGHR 463 T+T PS + T + T A V VP T T+ + A +L ++ Sbjct: 3154 TAT------PSSTPGTTWILTEPSTTATVTVPTGSTATASSTR----ATAGTLKVLTSTA 3203 Query: 464 ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPI-TSSVSTIRQYPVSAQ 522 +P ++ + P LP +A A + T I +SS+ T Sbjct: 3204 TTPTVISSRATPSSSPGTATA----LPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3259 Query: 523 APNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQ 582 P + ++ T TVH + + T + A G P ST G T Sbjct: 3260 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRAT---GSVATPSSTPG-------TAHTT 3309 Query: 583 PAPLGTQGIHSATPINTQGLQPAP----MGTQQPQPEGKTSAVVLADGATIVANPISNPF 638 P T +ATP ++ G P T P G T G T A ++ Sbjct: 3310 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT-- 3367 Query: 639 SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPR 698 TT V T S A+ ++ Q S PS+ AT A T P P Sbjct: 3368 -----TTTTVATGSM-ATPSSSTQTSGTPPSLTTT--ATTITATGSTTNPSSTP------ 3413 Query: 699 VESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPP- 757 G P + + AT + TV+ P+ A+ T P P Sbjct: 3414 ---------------GTTPIPPVLTTTATTPAATSSTVT------PSSALGTTHTPPVPN 3452 Query: 758 TIPTMIAAASPPSQPAV-------ALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVL 810 T T + PPS P A S I G IT P T + P + + + L Sbjct: 3453 TTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPAL 3512 Query: 811 GPPVPEIKVKE 821 P P + E Sbjct: 3513 SSPHPSSRTTE 3523 Score = 71.2 bits (173), Expect = 5e-12 Identities = 117/511 (22%), Positives = 179/511 (35%), Gaps = 94/511 (18%) Query: 243 SKVTTVLRPTSQLPNAAT--AQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 +++TT T + AT + P I+ + P T + +P AT S+T+A + Sbjct: 2440 TELTTTATTTESTGSTATPSSTPGTTWIL-----TEPSTTATVTVPTGSTATASSTQATA 2494 Query: 301 --PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 P ++TTA T ++ S +A +++ A + T+ +PS +LGT Sbjct: 2495 GTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPS-SSLGTTWT 2553 Query: 359 QLHTMAQKTIFSTGTPVAA-ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHS 417 +L T TP A +T P T+ ++T + + T T ++ T + + Sbjct: 2554 RLS--------QTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGT 2605 Query: 418 SHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDN 477 +H T V T+ P T+ R P ++ T Sbjct: 2606 AHTTKVLTTTTTGFTATPSSSPGTA--------------------RTLPVWISTTTTPTT 2645 Query: 478 RPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTI---------RQYPVSAQAPNSAI 528 R S T PS+ P HT T +T++ +T+ S P+ Sbjct: 2646 RGS----------TVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTT 2695 Query: 529 TAQTGVGVASTVHLNPMQLM-TVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG 587 TA T ST NP T PA S+ + +GT P P Sbjct: 2696 TATTITATGSTT--NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNT 2753 Query: 588 TQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTV 647 T H + L P+ T + TS + G T + P S S PAATT Sbjct: 2754 TATTHG------RSLSPSSPHTVRTAWTSATSGTL---GTTHITEP-STGTSHTPAATTG 2803 Query: 648 VQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTS 707 HS A SSP PS R T PP P ++ R+T+ Sbjct: 2804 TTQHSTPAL-------SSPHPS------------SRTTESPPSPGTTTPGHTRATSRTTA 2844 Query: 708 ----GSPRPAGAKPKSEIHVSMATPVTVSME 734 R + P S + T VT+ E Sbjct: 2845 TATPSKTRTSTLLPSSPTSAPITTVVTMGCE 2875 Score = 70.9 bits (172), Expect = 6e-12 Identities = 154/690 (22%), Positives = 230/690 (33%), Gaps = 102/690 (14%) Query: 251 PTSQLPNAATAQPAVQHIIHQPIQS----RPPVTTSNAIPPAVVATVSATRAQSPVITTT 306 PT++L A T QP S R P ++ A+P S + TT Sbjct: 1615 PTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATT 1674 Query: 307 AAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP-ALGTPK-QQLHTMA 364 T + + PT+ P A S + TR LP +LGT + Q T+A Sbjct: 1675 GGPTTPAGSTEPTV-----PGVATST--------LPTRSALPGTTGSLGTWRPSQPPTLA 1721 Query: 365 QKTIF-STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV 423 T+ S P A+ A T + T +S +QA TST T T S T Sbjct: 1722 PTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT---MSPLTNT 1778 Query: 424 TTSNIPVAKVVPQQITHTSPRIQ------PDYPA--------ERSSLIPISGHRASPNPV 469 TTS Q T P+ + D+P E I +G + P Sbjct: 1779 TTS---------QGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPK 1829 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT 529 ++E R++N P V + +T S+ T N T Sbjct: 1830 SIECRAENYPEVSID-----------------QVGQVLTCSLET------GLTCKNEDQT 1866 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQ 589 + + + N L D SH PA ST P GT I P T Sbjct: 1867 GRFNM----CFNYNVRVLCCDDYSHCPST----PATSSTATPSSTP-GTTWILTKPTTT- 1916 Query: 590 GIHSATPINTQGLQPAPMGTQQ--PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTV 647 AT + G P T + P P+ T+ + A P S+P +A Sbjct: 1917 ----ATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALR 1972 Query: 648 VQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTS 707 + +A++ P SS + R T A T P P+ A + +T+ Sbjct: 1973 STATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT 2032 Query: 708 GSPRPAGAKPKSEIHVSMAT--PVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAA 765 + A P S + T P T + + ++ T PP T T + Sbjct: 2033 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGST 2092 Query: 766 ASPPSQP-----AVALSTIPGAVP----ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPE 816 +P S P A L+T V TP +T + PPS+T + + G Sbjct: 2093 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 2152 Query: 817 IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQH 876 ++ + P +NTV+PS A L + P + R P H Sbjct: 2153 SSTPGTTPIPPVLTTTATTPAATSNTVTPSSA-LGTTHTPPVPNTMATTHGRSLPPSSPH 2211 Query: 877 VI-----STEEGDMMETNSTDDEKSTAKSL 901 + S G + T+ T+ T+ +L Sbjct: 2212 TVRTAWTSATSGILGTTHITEPSTVTSHTL 2241 Score = 67.0 bits (162), Expect = 9e-11 Identities = 115/479 (24%), Positives = 168/479 (35%), Gaps = 70/479 (14%) Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTST------------I 408 H + ST TP + IL T +ATT S T P+ST Sbjct: 3673 HCPSTPATSSTATPSSTPGTTWIL-TKLTTTATTTESTGSTATPSSTPGTTWILTEPSTT 3731 Query: 409 VTMTVPSHSSH--------------ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 T+TVP+ S+ +T TT + +K P +SP PA RS Sbjct: 3732 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP----FSSPGTATALPALRS 3787 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTI 514 + + + P + + R S + T PS+ P AHT T +T++ +T Sbjct: 3788 TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTT 3847 Query: 515 RQYPVSAQAPNSAITAQTGVGVASTVHLNPMQL--MTVDASHARHIQGIQPAPIST---- 568 R A S T + G A T + TV S + P IST Sbjct: 3848 R-------ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTP 3900 Query: 569 --QGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ---PQPEGKTSAVVL 623 G P PG P T + T + T + TQ P T+ + Sbjct: 3901 TTSGSTVTPSSVPGTTHTP--TVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTIT 3958 Query: 624 ADGATIVANPISNPFSAA--PAATTVVQTHSQSASTNAP--AQGSSPRPSILRKKPATDG 679 A G+T NP S P + P TT T + ++ST P A G++ P + T G Sbjct: 3959 ATGST--TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHG 4016 Query: 680 MAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET--VS 737 + + P P S+ T G+ + H AT T T +S Sbjct: 4017 RS-----LSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS-HTPAATTGTTQHSTPALS 4070 Query: 738 NQNNDQPTIAVPPTAQQPPP-----TIPTMIAAASPPSQPAVALSTIPGAVPITPPITT 791 + + T PP+ P T T A ++ + L + P + PIT +TT Sbjct: 4071 SPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4129 Score = 60.8 bits (146), Expect = 7e-09 Identities = 136/611 (22%), Positives = 209/611 (34%), Gaps = 79/611 (12%) Query: 39 STGLSQAPSQIANSGSAG--LINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 +TG + PS + L + A T S + + S+ ++ L S K Sbjct: 3008 TTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 3067 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 P P + +T P T P A ++ P S E + ++ Sbjct: 3068 SFTPIPSFTLGTT-----GTLPEQTTTPMATMSTIHPSSTPE---TTHTSTVLTTKATTT 3119 Query: 157 APPSTLSLPPKVPGQVTVTME---SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSI 213 S++S P PG + E ++ A+ P AT S G L TT Sbjct: 3120 RATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVP 3179 Query: 214 IRSNAPGPPLHIGASHLP--RGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 S A A L A + SS+ T S P ATA PA++ Sbjct: 3180 TGSTATASSTRATAGTLKVLTSTATTPTVISSRATP-----SSSPGTATALPALRSTA-- 3232 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSA----------LSRPTLS 321 + P T+ AIP + + T +Q+ T T + AT S+ L+ T + Sbjct: 3233 ---TTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTT 3289 Query: 322 IQHPPSAAISIQRPAQSRDVTTRI-TLPSHPALGTPKQQLHTMAQKTIF--STGTPVA-A 377 + S A P + TT++ T + TP T ++ +T TP Sbjct: 3290 TRATGSVATPSSTPGTAH--TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRG 3347 Query: 378 ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQ 437 +TV P ++IP T +V T T +M PS S+ + P Sbjct: 3348 STVTP----SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSG-----------TPPS 3392 Query: 438 ITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY 497 +T T+ I A S+ P S +P P + T + + T PS+ Sbjct: 3393 LTTTATTI----TATGSTTNPSSTPGTTPIPPVLTTTATTPAATS-------STVTPSSA 3441 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGV--GVASTVHLNPMQLMT--VDAS 553 HT P+ ++ +T + +P++ TA T G+ T H+ +T A+ Sbjct: 3442 LGTTHT-PPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAA 3500 Query: 554 HARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG--TQGIHSATPINTQGLQPAPMGTQQ 611 Q PA S P P P G T G T T P+ T Sbjct: 3501 TTSTTQHSTPALSS-----PHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTST 3555 Query: 612 PQPEGKTSAVV 622 P TSA + Sbjct: 3556 LLPSSPTSAPI 3566 Score = 59.7 bits (143), Expect = 1e-08 Identities = 108/474 (22%), Positives = 166/474 (35%), Gaps = 78/474 (16%) Query: 373 TPVAAATVAPI-------LATNTIPSATTAGSVSHTQAPT------------STIVTMTV 413 TP ++T P + T +ATT S T P+ ST T+TV Sbjct: 2420 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 2479 Query: 414 PSHSSH--------------ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 P+ S+ +T TT + +K P +SP PA RS+ Sbjct: 2480 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP----FSSPGTATALPALRSTATTP 2535 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + + P + + R S + T PS+ P HT T +T++ +T Sbjct: 2536 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT------ 2589 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI--------STQGI 571 A S T + G A T + A+ + + P+ +T+G Sbjct: 2590 -TGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS 2648 Query: 572 QPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQ---QPQPEGKTSAVVLADGAT 628 P PG P T + T + T + TQ P T+ + A G+T Sbjct: 2649 TVTPSSIPGTTHTP--TVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 2706 Query: 629 IVANPISNPFSA--APAATTVVQTHSQSASTNAP--AQGSSPRPSILRKKPATDGMAVRK 684 NP S P + P TT T + ++ST P A G++ P + T G + Sbjct: 2707 --TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRS--- 2761 Query: 685 TLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET--VSNQNND 742 + P P S+ T G+ + H AT T T +S+ + Sbjct: 2762 --LSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS-HTPAATTGTTQHSTPALSSPHPS 2818 Query: 743 QPTIAVPPTAQQPPPTIPTMIAAASPPSQPA----VALSTIPGAVPITPPITTI 792 T PP+ P T P A S + A ST+ + P + PITT+ Sbjct: 2819 SRTTESPPS---PGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2869 Score = 59.3 bits (142), Expect = 2e-08 Identities = 120/532 (22%), Positives = 187/532 (35%), Gaps = 86/532 (16%) Query: 39 STGLSQAPSQIANSGSAGLI---NPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEP 95 STG + PS + G+ ++ + ATV +G + S+ + + + + + Sbjct: 4436 STGSTATPS--STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 4493 Query: 96 VVVRPYPQVQMLSTHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSR 152 + P S+ A+A P T P A A+P S + T P+ Sbjct: 4494 TSSKATP-----SSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 4548 Query: 153 PIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 ++ A PS S P V +T ++ A+ VAT S G TT + Sbjct: 4549 TMSTATPS--STPETVHTSTVLTATATTTGATG-SVATPSSTPGTAHTTKVPTTTTTGFT 4605 Query: 213 IIRSNAPG----PPLHIGASHLPR-----------------GAAAAAVMSSSKVTTVLRP 251 S++PG PP+ I + P G A + ++ TTV Sbjct: 4606 ATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATG 4665 Query: 252 TSQLPNAATAQPAVQHIIHQPI------------QSRP------PVTTSNAIPPAVVATV 293 + P+++T + S P PV TS A PA ++ Sbjct: 4666 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSS- 4724 Query: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353 AT + SP TT T +A S PS+ + ++ T T+ + Sbjct: 4725 KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTS 4784 Query: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAP--------ILATNTIPSATTAGS-----VSH 400 TP + HT T +T T +T P IL T + TTA + +S Sbjct: 4785 STP-ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSS 4843 Query: 401 TQAPT------STIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 T T STI T+ VP+ S+ + T KVV T P + Sbjct: 4844 TPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMAT---------MPTATA 4894 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTP 506 S +P S + A+ S SV L T P+ +P ++H TP Sbjct: 4895 STVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFP-SSHFSTP 4945 Score = 58.9 bits (141), Expect = 2e-08 Identities = 115/512 (22%), Positives = 176/512 (34%), Gaps = 73/512 (14%) Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 H + ST TP + IL T +ATT + T P+ST T P Sbjct: 2973 HCPSTPATSSTATPSSTPGTTWILTEQTT-AATTTATTGSTAIPSSTPGTAPPPK----- 3026 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 +T+ P A + + +SPR P S+ + +P P + P Sbjct: 3027 VLTSTATTPTA-TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPE 3085 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 + T PS+ P HT T +T+ +T R S+ + S+ T + T Sbjct: 3086 QTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRA--TSSMSTPSSTPGTTWILTELTT 3143 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGI-----QPAPIGTPGIQPAPLGTQGIHSAT 595 A+ G P ST G +P+ T + P G+ S+T Sbjct: 3144 -----------AATTTAATGPTATPSSTPGTTWILTEPSTTATVTV---PTGSTATASST 3189 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSA 655 A GT + T+ V++ AT ++P +A PA + T + ++ Sbjct: 3190 R--------ATAGTLKVLTSTATTPTVISSRATPSSSP--GTATALPALRSTATTPTATS 3239 Query: 656 STNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGA 715 T P+ SS + R T A T P P+ + + +T+ + R G Sbjct: 3240 VTAIPS--SSLGTAWTRLSQTTTPTATMSTATPSSTPETV--HTSTVLTTTTTTTRATG- 3294 Query: 716 KPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPP-PTIPTMIAAASPPSQPAV 774 S+ATP + P TA PT T A+P S P Sbjct: 3295 --------SVATPSST-----------------PGTAHTTKVPTTTTTGFTATPSSSPGT 3329 Query: 775 ALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSA 834 AL+ T P T + P S+ ++VL + P + S Sbjct: 3330 ALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQ-TSG 3388 Query: 835 VPPLATNTVSPSLAL--LANNLSMP-TSDLPP 863 PP T T + A N S P T+ +PP Sbjct: 3389 TPPSLTTTATTITATGSTTNPSSTPGTTPIPP 3420 Score = 55.5 bits (132), Expect = 3e-07 Identities = 114/508 (22%), Positives = 171/508 (33%), Gaps = 74/508 (14%) Query: 130 PAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL-----PPKVPGQVTVTMESSIPQAS 184 P+ P + S P T + +T S P PG + E S Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 3734 Query: 185 AIPV---ATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMS 241 +P AT S Q + H+ TT ++ S A A+ LP + A + Sbjct: 3735 TVPTGSTATASSTQA-TAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 3793 Query: 242 SSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSP 301 ++ T + P+S L T + P T S A P + T S Sbjct: 3794 ATSFTAI--PSSSLGTTWTRLSQT---------TTPTATMSTATPSSTPETAHT----ST 3838 Query: 302 VITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLH 361 V+TTTA +R T S+ P S + TT T+ + GT + Sbjct: 3839 VLTTTAT------TTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTP-- 3890 Query: 362 TMAQKTIFSTGTPVAA-ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 I +T TP + +TV P +++P T +V T T +M PS S+ Sbjct: 3891 ---PVWISTTTTPTTSGSTVTP----SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 3943 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 + S I A + + T+P P +P P + T + + Sbjct: 3944 SGTPPSLITTATTITATGSTTNPSSTPG---------------TTPIPPVLTTTATTPAA 3988 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGV--GVAS 538 T PS+ HT P+ ++ +T +S +P++ TA T G Sbjct: 3989 TS-------STVTPSSALGTTHT-PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG 4040 Query: 539 TVHLNPMQLMT--VDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG--TQGIHSA 594 T H+ T A+ Q PA S P P P G T G +A Sbjct: 4041 TTHITEPSTGTSHTPAATTGTTQHSTPALSS-----PHPSSRTTESPPSPGTTTPGHTTA 4095 Query: 595 TPINTQGLQPAPMGTQQPQPEGKTSAVV 622 T T P+ T P TSA + Sbjct: 4096 TSRTTATATPSKTRTSTLLPSSPTSAPI 4123 Score = 54.7 bits (130), Expect = 5e-07 Identities = 158/776 (20%), Positives = 260/776 (33%), Gaps = 97/776 (12%) Query: 130 PAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL-----PPKVPGQVTVTMESSIPQAS 184 P+ P + S + P T + +T S P PG + E S Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 2477 Query: 185 AIPV---ATISGQQGHPSNLHHIMTTNVQMSIIRSNA-----PGPPLHIGA----SHLPR 232 +P AT S Q + H+ TT ++ S A PG + A + P Sbjct: 2478 TVPTGSTATASSTQA-TAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 2536 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 + A+ SSS TT R + AT A P + V TS + T Sbjct: 2537 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT------PSSTPETVHTSTVLTTTATTT 2590 Query: 293 VSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPA 352 + +P T AH T L+ T PS++ P +R + I+ + Sbjct: 2591 GATGSVATPSSTPGTAHTT-KVLTTTTTGFTATPSSS-----PGTARTLPVWISTTT--- 2641 Query: 353 LGTPKQQLHTMAQKTI-FSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM 411 TP + T+ +I +T TP T +AT ++ AT + S + P S T Sbjct: 2642 --TPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM--ATPSSSTQTSGTPPSLTTTA 2697 Query: 412 TVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPN--PV 469 T + + T S+ P +P +T T+ PA SS + S + + PV Sbjct: 2698 TTITATGSTT--NPSSTPGTTPIPPVLTTTATT-----PAATSSTVTPSSALGTTHTPPV 2750 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAY-----------PLAAHTYTPITSSVSTIRQYP 518 T + + S+ + + T SA P ++TP ++ +T P Sbjct: 2751 PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTP 2810 Query: 519 -VSAQAPNSAIT-AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPI 576 +S+ P+S T + G + H T A+ ++ + P S + Sbjct: 2811 ALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSK-TRTSTLLPSSPTSAPITTV 2869 Query: 577 GTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISN 636 T G +P ++ + + P+ P P G + T + + A G + P+ Sbjct: 2870 VTMGCEPQCAWSEWLDYSYPM------PGPSGG-----DFDTYSNIRAAGGAVCEQPLGL 2918 Query: 637 PFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIP----PQPP 692 A ++ Q + + K +R P P Sbjct: 2919 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTP 2978 Query: 693 DVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQ-NNDQPTIAVPPT 751 +TS + P+ + I T T + T S + P A PP Sbjct: 2979 ------------ATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPK 3026 Query: 752 AQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLG 811 T PT ++ + S +T+P T + P PS T+G + Sbjct: 3027 VLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTT------ 3080 Query: 812 PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLAN-NLSMPTSDLPPGAS 866 +PE + + M + P S T+TV + A SM T PG + Sbjct: 3081 GTLPE-QTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3135 Score = 36.6 bits (83), Expect = 0.13 Identities = 46/198 (23%), Positives = 69/198 (34%), Gaps = 21/198 (10%) Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPMGTQQP-----QPEGKTSAVVLADGATIVANPI 634 G P T + +AT TQ L P T P P T+ L++G T + Sbjct: 1608 GRATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLT--SPRY 1665 Query: 635 SNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDV 694 ++ A S + A + P S L P T G T P QPP + Sbjct: 1666 TSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSAL---PGTTGSL--GTWRPSQPPTL 1720 Query: 695 ASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 754 A + +S +G+ A +P + S+A +T + T Q + P T Sbjct: 1721 APTTMATSRARPTGTASTASKEP---LTTSLAPTLTSELST------SQAETSTPRTETT 1771 Query: 755 PPPTIPTMIAAASPPSQP 772 P T + + QP Sbjct: 1772 MSPLTNTTTSQGTTRCQP 1789 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 91.3 bits (225), Expect = 5e-18 Identities = 134/528 (25%), Positives = 189/528 (35%), Gaps = 81/528 (15%) Query: 371 TGTPVAAATVAPILATNTI-PSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP 429 T T T PI T T+ P+ T + S T P +T T+T + TT+ I Sbjct: 1304 TTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPIT 1363 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFL 489 V T T + P ++ + +P P +T + S P+ Sbjct: 1364 TTTTVTPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPT----STPIT---TT 1411 Query: 490 PTYPPSAYPLAAH--TYTPITSSVS-TIRQYPVSAQAPN-SAITAQTGVGVASTVHLNPM 545 T P+ P T TPIT++ + T P QAP +AIT + V T P Sbjct: 1412 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPT----PT 1467 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIG-----TPGIQPAPLGTQGIHSATPINTQ 600 T + + P P T P P T P P GTQ ++TPI T Sbjct: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQ-TPTSTPITTT 1526 Query: 601 GL---QPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQTHSQSAS 656 P P GTQ P P PIS + P T T QT + + Sbjct: 1527 TTVTPTPTPTGTQTPTP-----------------TPISTTTTVTPTPTPTGTQTPTTTPI 1569 Query: 657 TNAPAQGSSPRPSILRKKPATDGMAVRKTLIP-PQPPDVASPRVE--SSMRSTSGSPRPA 713 T +P P+ + P T + T+ P P P S V ++ + + +P P Sbjct: 1570 TTTTTVTPTPTPT-GTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPT 1628 Query: 714 GAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP----TAQQPPP---TIPTMIAAA 766 G + + I +S T VT + + + P T PPP T T + + Sbjct: 1629 GTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS 1688 Query: 767 SPPSQPAVALSTIPGAVPIT---PPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEV 823 SP ++ LST+P A+ +T PP T A P+ T GG L PP Sbjct: 1689 SPLTESTTLLSTLPPAIEMTSTAPPSTPTA----PTTTSGG---HTLSPP---------- 1731 Query: 824 EPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKP 871 P P P T T S S + + TS P +P P Sbjct: 1732 -PSTTTSP-PGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 1777 Score = 90.1 bits (222), Expect = 1e-17 Identities = 118/530 (22%), Positives = 178/530 (33%), Gaps = 84/530 (15%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 P+TT+ + P T + + +P+ TTT T + PT Q P Sbjct: 1315 PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPT----PT-----------GTQTPTT 1359 Query: 338 SRDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSAT 393 + TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 1360 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1419 Query: 394 TAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAER 453 G+ + T P +T T+T + A T + I V T T + P Sbjct: 1420 PTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITT 1479 Query: 454 SSLI---PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSS 510 ++ + P +P P A+ T + P+ P PT P T TP + Sbjct: 1480 TTTVTPTPTPTGTQTPTPTAITTTTTVTPT-PTPTGTQTPTSTPITTTTTV-TPTPTPTG 1537 Query: 511 VSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P+S + TG +T + +T P P TQ Sbjct: 1538 TQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-----------PTPTGTQT 1586 Query: 571 IQPAPIGTPGIQ---PAPLGTQGIHSATPINTQGL---QPAPMGTQQPQPEGKTSAVVLA 624 I T P P T+ + TPI T P P GTQ P + + ++ Sbjct: 1587 PTTVLITTTTTMTPTPTPTSTKST-TVTPITTTTTVTATPTPTGTQTP------TMIPIS 1639 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRK 684 T+ P S P T ++ ++N P + S+P+ S P T+ + Sbjct: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLS 1699 Query: 685 TLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQP 744 TL PP + M ST+ P S H Sbjct: 1700 TL----PPAI-------EMTSTAPPSTPTAPTTTSGGH---------------------- 1726 Query: 745 TIAVPPTAQQPPPTIP---TMIAAASPPSQPAVALSTIPGAVPITPPITT 791 T++ PP+ PP P T ++S P+ V +T P P++T Sbjct: 1727 TLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST 1776 Score = 79.7 bits (195), Expect = 1e-14 Identities = 125/564 (22%), Positives = 194/564 (34%), Gaps = 89/564 (15%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAA 329 P+TT+ + P T + T +P+ TTT T + T + P Sbjct: 1338 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1397 Query: 330 ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP----ILA 385 Q P + TT P+ GT + T T T TP T AP I Sbjct: 1398 TGTQTPTSTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQAPTPTAITT 1456 Query: 386 TNTI-PSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPR 444 T+T+ P+ T G+ + T P +T T+T + T + I V T T + Sbjct: 1457 TSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQ 1516 Query: 445 IQPDYPAERSSLI---PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAA 501 P ++ + P +P P + T + P+ PT + P Sbjct: 1517 TPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT---------PTPTGTQTP--- 1564 Query: 502 HTYTPITSSVS-TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQG 560 T TPIT++ + T P Q P + + T + T + TV Sbjct: 1565 -TTTPITTTTTVTPTPTPTGTQTPTTVLITTTTT-MTPTPTPTSTKSTTVTPITTTTTVT 1622 Query: 561 IQPAPISTQGIQPAPIGTPG-IQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKT- 618 P P TQ PI T + P P T G + P +T A + T P PE T Sbjct: 1623 ATPTPTGTQTPTMIPISTTTTVTPTPTPTTG-STGPPTHTSTAPIAELTTSNPPPESSTP 1681 Query: 619 -----SAVVLADGATIVAN--PISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671 ++ L + T+++ P S AP +T T + T +P ++ P Sbjct: 1682 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 1741 Query: 672 RKKPATDGMAVRKT----------LIPPQPPDVASPRVESSMRSTSGSPRPAGA------ 715 + T G + T P P +++P + +R+T P P+ Sbjct: 1742 PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSI---IRTTGLRPYPSSVLICCVL 1798 Query: 716 -----KPKSEIH----------VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP 760 P E++ V+ + T+ S + PT PT P + P Sbjct: 1799 NDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT----PT---PSKSTP 1851 Query: 761 TMIAAASPPSQPAVALSTIPGAVP 784 T +S PS+P PG P Sbjct: 1852 TPSKPSSTPSKPT------PGTKP 1869 Score = 79.0 bits (193), Expect = 2e-14 Identities = 122/535 (22%), Positives = 177/535 (33%), Gaps = 94/535 (17%) Query: 91 EKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMP 150 E P + V T + S TP +T T P G P P Sbjct: 1309 ENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTT----TTVTPTPTPTGTQTPTTTPITT 1364 Query: 151 SRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQAS------AIPVATISGQQGHPSNLHHI 204 + + P P T + P T T + P + + P+ T + P+ Sbjct: 1365 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ 1424 Query: 205 MTTNVQMSIIRSNAPGPPLHIGASHLPRGAAA---AAVMSSSKVTTVLRPTSQLPNAATA 261 T ++ + P P P G A A+ ++S VT PT T Sbjct: 1425 TPTTTPITTTTTVTPTPT--------PTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTP 1476 Query: 262 QPAVQHIIHQPI----QSRPP--VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSAL 315 + P Q+ P +TT+ + P T + T +P+ TTT T + Sbjct: 1477 ITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPT 1536 Query: 316 SRPT--------LSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQ---LHTMA 364 T + P Q P + TT P+ GT + T Sbjct: 1537 GTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTT 1596 Query: 365 QKTIFSTGTPVAAATVAPILATNTIPSATT-AGSVSHTQAPTSTIVTMTV---------- 413 T T T + TV PI T T+ + T G+ + T P ST T+T Sbjct: 1597 TMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTG 1656 Query: 414 -PSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVA 470 P+H+S A +TTSN P PQ TS + E ++L+ S P A Sbjct: 1657 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL-----TESTTLL-------STLPPA 1704 Query: 471 METRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA 530 +E S PS P T TS T+ P + +P T Sbjct: 1705 IEMTSTAPPSTP--------------------TAPTTTSGGHTLSPPPSTTTSPPGTPTR 1744 Query: 531 QTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAP 585 T G +S + +Q T A P P+ST P+ I T G++P P Sbjct: 1745 GTTTGSSSAPTPSTVQTTTTSAWTP------TPTPLST----PSIIRTTGLRPYP 1789 Score = 40.8 bits (94), Expect = 0.007 Identities = 49/234 (20%), Positives = 82/234 (35%), Gaps = 19/234 (8%) Query: 642 PAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVES 701 P T T + + + +P P+ + T T + P P + + Sbjct: 1300 PTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTT 1359 Query: 702 SMRST----SGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPP 757 + +T + +P P G + + ++ T VT + Q PT T P Sbjct: 1360 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---PTSTPITTTTTVTP 1416 Query: 758 TIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEI 817 T PT +P + P +T V TP T A P ++T + S+V P P Sbjct: 1417 T-PTPTGTQTPTTTPITTTTT----VTPTPTPTGTQAPTPTAIT---TTSTVTPTPTPTG 1468 Query: 818 KVKEEVEPMDIMRPVSAVP-PLATNTVSPSLALLANNLS---MPTSDLPPGASP 867 P+ V+ P P T T +P+ ++ PT P ++P Sbjct: 1469 TQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTP 1522 Score = 38.9 bits (89), Expect = 0.027 Identities = 34/125 (27%), Positives = 44/125 (35%), Gaps = 16/125 (12%) Query: 743 QPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTV 802 QPT T + P PT T +P P ST P TP TT P P+ T Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTP-----TPITTTTTVTPTPTPT- 1352 Query: 803 GGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 862 G+ + P V P P + P T TV+P+ PT Sbjct: 1353 -GTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPT--------PTPTGTQT 1402 Query: 863 PGASP 867 P ++P Sbjct: 1403 PTSTP 1407 >gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 673 Score = 84.0 bits (206), Expect = 7e-16 Identities = 164/689 (23%), Positives = 265/689 (38%), Gaps = 90/689 (13%) Query: 231 PRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ----PAVQHIIHQPIQSRPPVTTSNAIP 286 P A+ S++ +T S +TA P+ + P ++ TTS A Sbjct: 8 PSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASL 67 Query: 287 PAVVATVSATRAQSP-VITTTAAHATDSAL--------SRPTLSIQHPPSAAISIQRPAQ 337 + S TR QS ++T T + A+ + + P S+ PS A + P++ Sbjct: 68 MVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSR 127 Query: 338 SRDVTTRITLPSHPALG-TPKQQLH-TMAQKTIFSTGTPVAAATVAPILA--TNTIPSAT 393 + TT PS +L TP TM + + P A+ T+ P A T T P A+ Sbjct: 128 ASLTTT----PSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRAS 183 Query: 394 TAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAER 453 G S T +PT T ++ S A+ T +++ P T T PR P R Sbjct: 184 PTGMPSRT-SPTGMPSTASLTKMDSTASITRT----LSRASP---TGTPPRASPTGSPPR 235 Query: 454 SSL--IPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 +SL +P + P A T +R S+ T PS A+ T TP +S+ Sbjct: 236 ASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASL 295 Query: 512 ST-------IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA 564 S +R P ++ + T+ T + +++ P + ++ + +R +P+ Sbjct: 296 SMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRA-SITRTPSRASPTGKPS 354 Query: 565 PISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQ-QPQPEGKTSAVVL 623 S P GTP + +P G+ S T +++ +P GT + P G S Sbjct: 355 TAS-------PTGTPS-RASPTGSPSTASLTGLSSTA---SPTGTPPRASPTGTPST--- 400 Query: 624 ADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQ----GSSPRPSILRKKPATDG 679 A++ P + + T++ + S ++ T P + G+ PR S Sbjct: 401 ---ASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASP 457 Query: 680 MAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQ 739 + T P P ASP S S +GSP A + ++ S+ T + + Sbjct: 458 TGTQSTASPTGSPSTASPTGSPSTASPTGSPSRA-SLTRTPSRASL-TKMESTASITRTP 515 Query: 740 NNDQPTIAVPPTAQQPPPTIPTMIAAASP--------PSQ------PAVALSTIPGAVPI 785 + PT P+ P + T +A SP PS+ P+ A T P + Sbjct: 516 SRASPTWT--PSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASL 573 Query: 786 T-PPITTIAAAPPPSVTVGG--SLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 842 T P T + PPS + G S +S G P + K MD ++ PP A+ T Sbjct: 574 TRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTK-----MDSTASITRTPPRASPT 628 Query: 843 VSPSLALLANNLSMPTSDLPPGASPRKKP 871 +P A+ P P G PR P Sbjct: 629 ETPP---RASPTGTPPRASPTGTPPRASP 654 Score = 33.5 bits (75), Expect = 1.1 Identities = 58/244 (23%), Positives = 85/244 (34%), Gaps = 39/244 (15%) Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA 747 P + P ASP S S +G+P A M TP S+ + + + T + Sbjct: 4 PTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTS 63 Query: 748 VPPTAQQPPPTIPTMIAAAS--------------PPSQPAVALSTIPGAVPITPPITTIA 793 + P T + ++S PP A T+P A + P T Sbjct: 64 MASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPR--ASRTRTLPRASLMRRPSTASL 121 Query: 794 AAPP--PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLA 851 P S+T S +S+ P + M ++ PP A+ T++PS A L Sbjct: 122 TRSPSRASLTTTPSRASLSMTPSTAAAL-----TMPSRASLTRTPPRASLTMTPSTASLT 176 Query: 852 NNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAK--SLLVKAEKRK 909 PP ASP P + T M T S STA L +A Sbjct: 177 RT--------PPRASPTGMPSR------TSPTGMPSTASLTKMDSTASITRTLSRASPTG 222 Query: 910 SPPK 913 +PP+ Sbjct: 223 TPPR 226 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 83.6 bits (205), Expect = 9e-16 Identities = 189/895 (21%), Positives = 302/895 (33%), Gaps = 157/895 (17%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS+ P+ Sbjct: 4304 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST---PETAH 4360 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG----PPLHIG 226 TV ++ + VAT S G TT ++ S++PG PP+ I Sbjct: 4361 TSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIS 4420 Query: 227 ASHLPRGAAAAAVMSS------------SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 + P + + SS + TTV + P+++T H P+ Sbjct: 4421 TTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHT--PPVP 4478 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 + T ++ P+ TV + T H T+ P+ H P+A Sbjct: 4479 NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITE-----PSTGTSHTPAA------ 4527 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 TT T S PAL +P P + T +P T P TT Sbjct: 4528 -------TTGTTQHSTPALSSPH----------------PSSRTTESPPSPGTTTPGHTT 4564 Query: 395 AGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPD-YP 450 A S + T P+ T + +PS + A T V T+ + + ++ P P Sbjct: 4565 ATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGD 4624 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPV--------------------------- 483 + S I +G P+ +E R+ +P VP+ Sbjct: 4625 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFK 4684 Query: 484 -----QFQYFLPTYP--PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 + + F Y PS P + T P ++ +T ++ A +A T T Sbjct: 4685 MCFNYEIRVFCCNYGHCPST-PATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPS 4743 Query: 537 ASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGT--------PGIQPAPLGT 588 ++ P +++T A+ + S + P+ T + P P T Sbjct: 4744 STPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSST 4803 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLADGATIVANPISNPFSAAPAATT 646 G P T A M T P PE ++ VL AT S ++ TT Sbjct: 4804 LGTTGTLPEQTT-TPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTT 4862 Query: 647 VVQTHSQSASTNAPAQGSSPRPS-------ILRK------------KPATDGMAVRKTLI 687 + T +A+T A G + PS IL + AT T I Sbjct: 4863 WILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWI 4922 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVS-MATPVTVSMETVSNQNNDQPTI 746 +P A+ V + +T+ S + P HVS AT TV+ + ++ Sbjct: 4923 LTEPSTTATVTVPTGSTATASSTQATAGTP----HVSTTATTPTVTSSKATPSSSPGTAT 4978 Query: 747 AVP--------PTAQQ----PPPTIPTMIAAASPPSQPAVALST-IPGAVPITPPITTIA 793 A+P PTA P ++ T S + P +ST P + P T +T+ Sbjct: 4979 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVL 5038 Query: 794 AAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT--VSPSLALLA 851 A + T G+ SV P P +A P + T P+ ++ Sbjct: 5039 TA---TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMS 5095 Query: 852 NNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAE 906 ++ TS P + V++T TNST ST + + E Sbjct: 5096 TMSTIHTSSTP-------ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTE 5143 Score = 81.3 bits (199), Expect = 5e-15 Identities = 169/780 (21%), Positives = 267/780 (34%), Gaps = 133/780 (17%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS S P V Sbjct: 3157 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS--STPETVHT 3214 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP----PLHIG 226 +T ++ A+ VAT S G + TT + S++PG P+ I Sbjct: 3215 STVLTTTATTTGATG-SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIS 3273 Query: 227 ASHLPRGAAAAAVMSS------------SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 + P + SS + TTV + P+++T H P+ Sbjct: 3274 TTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHT--PPVP 3331 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 + T ++ P+ TV + T H T+ P+ H P+A Sbjct: 3332 NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITE-----PSTGTSHTPAA------ 3380 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 TT T S PAL +P T T TP + AT T PS T Sbjct: 3381 -------TTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATAT-PSKTR 3432 Query: 395 AGSV---SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPD-YP 450 ++ S T AP +T+VTM + + + + ++ P P Sbjct: 3433 TSTLLPSSPTSAPITTVVTMGCEPQCAWS---------------EWLDYSYPMPGPSGGD 3477 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPVQ-------------------------- 484 + S I +G P+ +E R+ +P VP++ Sbjct: 3478 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFK 3537 Query: 485 --FQYFLPTY------PPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 F Y + + PS P + T TP ++ +T + A +A T T + Sbjct: 3538 MCFNYEIRVFCCNYGHCPST-PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPS 3596 Query: 537 ASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGT--------PGIQPAPLGT 588 ++ P +++T A+ + S + P+ T P P T Sbjct: 3597 STPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFT 3656 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLADGATIVANPISNPFSAAPAATT 646 G P T A M T P PE ++ VL AT S ++ TT Sbjct: 3657 LGTTGTLPEQTT-TPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715 Query: 647 VVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRST 706 + T +A+T A G + PS P T T I +P A+ V + +T Sbjct: 3716 WILTELTTAATTTAATGPTATPS---STPGT-------TWILTEPSTTATVTVPTGSTAT 3765 Query: 707 SGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMI 763 + S R K + S AT TV + ++ A+P TA P T T I Sbjct: 3766 ASSTRATAGTLK--VLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAI 3823 Query: 764 AAA---------SPPSQPAVALST-IPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPP 813 ++ S + P +ST P + P T +T+ + GS+++ P Sbjct: 3824 PSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTP 3883 Score = 81.3 bits (199), Expect = 5e-15 Identities = 186/846 (21%), Positives = 289/846 (34%), Gaps = 145/846 (17%) Query: 108 STHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL 164 S+ A+A P T P A A+P S + T P+ ++ A PS S Sbjct: 3796 SSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPS--ST 3853 Query: 165 PPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG---- 220 P V +T ++ +A+ VAT S G TT + S++PG Sbjct: 3854 PETVHTSTVLTTTTTTTRATG-SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3912 Query: 221 PPLHIGASHLPR------------GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHI 268 PP+ I + P G A + ++ TTV + P+++T H Sbjct: 3913 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT 3972 Query: 269 IHQPIQSRPPVTTSNAIPPAVVATVSA--TRAQSPVITTTAAHATDSALSRPTLSIQHPP 326 P+ + T ++PP+ TV T A S ++ TT H T+ P+ H P Sbjct: 3973 --PPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT--HITE-----PSTVTSHTP 4023 Query: 327 SAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILAT 386 +A TT T S PAL +P T T +P + T P Sbjct: 4024 AA-------------TTSTTQHSTPALSSPHPSSRT--------TESPPSPGTTTPGHTR 4062 Query: 387 NTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPR 444 T S TTA T P+ T + +PS + A T V T+ + + ++ P Sbjct: 4063 GT--SRTTA-----TATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPM 4115 Query: 445 IQPDY-PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQ------------------- 484 P + S I +G P+ +E R+ +P VP++ Sbjct: 4116 PGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNR 4175 Query: 485 ---------FQYFL----------PTYP-------PSAYPLAAHTYTPITSSVSTIRQYP 518 F Y + P+ P PS+ P T +T++ +T Sbjct: 4176 EQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTG 4235 Query: 519 VSAQAPNSAITAQ--TGVGVASTVHLNPMQLMTVDASHAR----HIQGIQPAPISTQGIQ 572 +A ++ T T +TV + T ++ A H+ P T + Sbjct: 4236 STATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS-K 4294 Query: 573 PAPIGTPGIQPA-PLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA 631 P +PG A P + T + + + +GT + T+ AT Sbjct: 4295 ATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT--- 4351 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQP 691 P S P +A + + A+ + S+P + K P T T+ P Sbjct: 4352 -PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGF--TVTPSSS 4408 Query: 692 PDVA-SPRV---ESSMRSTSGSPRPAGAKPKSE-----IHVSMATPVTVSMETVSNQNND 742 P A +P V ++ +TSGS + P + + + T T SM T S+ Sbjct: 4409 PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 4468 Query: 743 QPTIAVPPTAQQPPPTIPTMIAAASPPSQP-------AVALSTIPGAVPITPPITTIAAA 795 T PP P T T + PS P A S G IT P T + Sbjct: 4469 SGTTHTPPV----PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT 4524 Query: 796 PPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP-VSAVPPLATNTVSPSLALLANNL 854 P + + L P P + E P + T T +PS + L Sbjct: 4525 PAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLL 4584 Query: 855 -SMPTS 859 S PTS Sbjct: 4585 PSSPTS 4590 Score = 72.8 bits (177), Expect = 2e-12 Identities = 156/696 (22%), Positives = 235/696 (33%), Gaps = 93/696 (13%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTV 174 +++P APPA T AVP + SEGL P T+ + S P VPG T Sbjct: 2327 TSSPGLTRAPPASTT-AVP-TLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVAT- 2383 Query: 175 TMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGA 234 S++P SA+P T S PS + T + S R AS P Sbjct: 2384 ---STLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAST----ASKEPLTT 2436 Query: 235 AAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVT----------TSNA 284 + A + +S+++T TS T P Q P ++ Sbjct: 2437 SLAPTL-TSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSG 2495 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP---SAAISIQRPAQSRDV 341 + + T RA + A + P +SI + ++ ++ D Sbjct: 2496 VAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQ 2555 Query: 342 TTRITL--PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVS 399 T R + + + H + ST TP + IL T +ATT S Sbjct: 2556 TGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWIL-TKPTTTATTTASTG 2614 Query: 400 HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 T PTST+ T P T TT + +K P +SP PA RS+ Sbjct: 2615 STATPTSTL--RTAPPPKVLTTTATTPTVTSSKATPS----SSPGTATALPALRSTATTP 2668 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + +P P + + R S + T PS+ P AHT T +T++ +T Sbjct: 2669 TATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT------ 2722 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A S T + G A T + +T G P +P Sbjct: 2723 -TGATGSVATPSSTPGTAHTTKV---------------------PTTTTTGFTATPSSSP 2760 Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFS 639 G P I + T T+G P P +A VL T V Sbjct: 2761 GTALTP--PVWISTTTTPTTRGSTVTPSSI----PGTTHTATVLTTTTTTV--------- 2805 Query: 640 AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRV 699 AT + T S S T+ G++ P + T G + +PP P Sbjct: 2806 ----ATGSMATPSSSTQTS----GTTHTPPVPNTMATTHGRS-----LPPSSPHTVRTAW 2852 Query: 700 ESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET--VSNQNNDQPTIAVPPTAQQPPP 757 S+ G+ + H AT T T +S+ + T PP+ P Sbjct: 2853 TSATSGILGTTHITEPSTVTS-HTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP 2911 Query: 758 TIPTMIAAASPPSQPA-VALSTIPGAVPITPPITTI 792 T + + + P+ ST+ + P + PITT+ Sbjct: 2912 GHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2947 Score = 70.9 bits (172), Expect = 6e-12 Identities = 196/883 (22%), Positives = 296/883 (33%), Gaps = 186/883 (21%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPA-HLTPAVPLSFSEGLMKPPPKPTM---- 149 P V+ +++ A S++P TA PA T P + S + P P ++ Sbjct: 2629 PKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS---VTPIPSSSLGTTW 2685 Query: 150 -----PSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 + P A +T S P+ TV ++ + VAT S G Sbjct: 2686 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 2745 Query: 205 MTTNVQMSIIRSNAPG----PPLHIGASHLPR------------GAAAAAVMSSSKVTTV 248 TT + S++PG PP+ I + P G A + ++ TTV Sbjct: 2746 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 2805 Query: 249 LRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSA--TRAQSPVITTT 306 + P+++T H P+ + T ++PP+ TV T A S ++ TT Sbjct: 2806 ATGSMATPSSSTQTSGTTHT--PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTT 2863 Query: 307 AAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQK 366 H T+ P+ H +A TT T S PAL +P Sbjct: 2864 --HITE-----PSTVTSHTLAA-------------TTGTTQHSTPALSSPH--------- 2894 Query: 367 TIFSTGTPVAAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAV 423 P + T +P T P TTA S + T P+ T + +PS + A T V Sbjct: 2895 -------PSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2947 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVP 482 T + + ++ P P + S I +G P+ +E R+ +P VP Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3007 Query: 483 VQ----------------------------FQYFL----------PTYP-------PSAY 497 ++ F Y + P+ P PS+ Sbjct: 3008 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 3067 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA--QTGVGVASTVHLNPMQLMTVDASHA 555 P T +T++ +T +A ++ T T +TV + T ++ A Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQA 3127 Query: 556 R----HIQGIQPAPISTQGIQPAPIGTPGIQ---PAPLGTQGIHSAT-----PINTQG-- 601 H+ P T + P +PG PA T +AT P ++ G Sbjct: 3128 TAGTPHVSTTATTPTVTSS-KATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3186 Query: 602 --------LQPAPMGTQQPQ--PEGKTSAVVLADGATI------VANPISNPFSAAPAAT 645 A M T P PE ++ VL AT VA P S P A T Sbjct: 3187 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTP---GTAHT 3243 Query: 646 TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRS 705 T V T + + T P S P R P + + T P +P SS+ Sbjct: 3244 TKVLTTTTTGFTATP----SSSPGTARTLP----VWISTTTTPTTRGSTVTP---SSIPG 3292 Query: 706 TSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAA 765 T+ +P + + + T T SM T S+ T PP P T T Sbjct: 3293 TTHTP--------TVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV----PNTTATTHGR 3340 Query: 766 ASPPSQP-------AVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIK 818 + PS P A S G IT P T + P + + L P P + Sbjct: 3341 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 3400 Query: 819 VKEEVEPMDIMRP-VSAVPPLATNTVSPSLALLANNL-SMPTS 859 E P + T T +PS + L S PTS Sbjct: 3401 TTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTS 3443 Score = 70.9 bits (172), Expect = 6e-12 Identities = 95/427 (22%), Positives = 160/427 (37%), Gaps = 65/427 (15%) Query: 243 SKVTTVLRPTSQLPNAAT--AQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 +++TT T + AT + P I+ + P T + +P AT S+T+A + Sbjct: 3075 TELTTTATTTESTGSTATPSSTPGTTWIL-----TEPSTTATVTVPTGSTATASSTQATA 3129 Query: 301 --PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 P ++TTA T ++ S +A +++ A + T+ +PS +LGT Sbjct: 3130 GTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPS-SSLGTTWT 3188 Query: 359 QLHTMAQKTIFSTGTPVAA-ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHS 417 +L T TP A +T P T+ ++T + + T T ++ T + + Sbjct: 3189 RLS--------QTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGT 3240 Query: 418 SHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDN 477 +H T V T+ P T+ R P ++ T Sbjct: 3241 AHTTKVLTTTTTGFTATPSSSPGTA--------------------RTLPVWISTTTTPTT 3280 Query: 478 RPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVA 537 R S T PS+ P HT T +T++ +T+ A S T + + Sbjct: 3281 RGS----------TVTPSSIPGTTHTPTVLTTTTTTV--------ATGSMATPSSSTQTS 3322 Query: 538 STVHLNPMQLMTVDASHARHIQGIQPAPIST--QGIQPAPIGTPGIQPAPLGTQGIHSAT 595 T H P+ T +H R + P + T +GT I GT +AT Sbjct: 3323 GTTHTPPVP-NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 3381 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHS--Q 653 TQ PA P P +T+ + G T + + + A A + +T + Sbjct: 3382 TGTTQHSTPA---LSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLP 3438 Query: 654 SASTNAP 660 S+ T+AP Sbjct: 3439 SSPTSAP 3445 Score = 69.7 bits (169), Expect = 1e-11 Identities = 177/789 (22%), Positives = 263/789 (33%), Gaps = 95/789 (12%) Query: 115 SATPVAVTAPPAHLTPAVPLSF-SEGLMKPPPKP--------TMPSRPIAPAPPS---TL 162 S TP A T H TPA+ S + PP P T SR A A PS T Sbjct: 4522 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS 4581 Query: 163 SLPPKVPGQV---TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS--IIRSN 217 +L P P TV PQ + S PS +N++ + + Sbjct: 4582 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4641 Query: 218 APGPPLHIGASH-LPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHII-----HQ 271 G A +P G V S V R Q+ + H Sbjct: 4642 PLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 4701 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 P P T+S A+P + T + TTTA+ + +A T PP S Sbjct: 4702 P---STPATSSTAMPSSTPGTTWILTELTTTATTTASTGS-TATPSSTPGTAPPPKVLTS 4757 Query: 332 IQRPAQSRDVTT-RITLPSHPALGTPKQQLHTMAQK------------TIFSTGTPVAAA 378 PA + T+ + T S P T L + A K T+ +TGT + Sbjct: 4758 ---PATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT-LPEQ 4813 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI 438 T P+ +TI ++T + TST++T + + ++ T S+ P + ++ Sbjct: 4814 TTTPVATMSTIHPSSTPETTH-----TSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL 4868 Query: 439 THTSPRIQPDYPAERSSLIP----ISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPP 494 T + P S P I + T S PS + L Sbjct: 4869 TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWIL----- 4923 Query: 495 SAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 P T T T S +T +A P+ + TA T V S+ T A Sbjct: 4924 -TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT-VTSSKATPSSSPGTATALP 4981 Query: 555 ARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQP 614 A P S I + +GT T+ + TP T + Sbjct: 4982 ALRSTATTPTATSFTAIPSSSLGT-------TWTRLSQTTTPTATMSTATPSSTPETVHT 5034 Query: 615 EGKTSAVVLADGAT-IVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRK 673 +A GAT VA P S P A TT V T + + T P S P Sbjct: 5035 STVLTATATTTGATGSVATPSSTP---GTAHTTKVPTTTTTGFTATP----SSSPGTALT 5087 Query: 674 KPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVS-MATPVTVS 732 P T M+ T+ P+ + +T + A P S + + + T +T + Sbjct: 5088 PPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTT 5147 Query: 733 METVSNQNNDQPTIAVPPTA--QQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT 790 T + + + P T P TI T++ P A A ST+ G +T Sbjct: 5148 ATTTAATGSTATLSSTPGTTWILTEPSTIATVMV---PTGSTATASSTL-GTAHTPKVVT 5203 Query: 791 TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALL 850 T+A P + + S S+V P + S++P + +TVS S+ Sbjct: 5204 TMATMPTATASTVPSSSTVGTTRTPAVL-------------PSSLPTFSVSTVSSSVLTT 5250 Query: 851 ANNLSMPTS 859 P+S Sbjct: 5251 LRPTGFPSS 5259 Score = 68.6 bits (166), Expect = 3e-11 Identities = 122/559 (21%), Positives = 193/559 (34%), Gaps = 83/559 (14%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 P T+S A P + T Q+ TTTA + +A+ T PP S Sbjct: 3558 PATSSTATPSSTPGTTWILTEQTTAATTTATTGS-TAIPSSTPGTAPPPKVLTSTATTPT 3616 Query: 338 SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGS 397 + +++ T S P T L + A K+ ++ TP+ + T+ T T+P TT Sbjct: 3617 A--TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLG---TTGTLPEQTTT-- 3669 Query: 398 VSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLI 457 A STI + P + +T +TT A + ++P P + L Sbjct: 3670 ---PMATMSTIHPSSTPETTHTSTVLTTK----ATTTRATSSMSTPSSTPGTTWILTELT 3722 Query: 458 PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT-PITSSVSTIRQ 516 + A+ P A PS+ P T P T++ T+ Sbjct: 3723 TAATTTAATGPTAT----------------------PSSTPGTTWILTEPSTTATVTV-- 3758 Query: 517 YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPI 576 P + A S+ A G ++++T A+ P IS++ + Sbjct: 3759 -PTGSTATASSTRATAGT----------LKVLTSTAT--------TPTVISSRATPSSSP 3799 Query: 577 GTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISN 636 GT PA T +AT + + + +GT + T+ AT P S Sbjct: 3800 GTATALPALRSTATTPTATSVTA--IPSSSLGTAWTRLSQTTTPTATMSTAT----PSST 3853 Query: 637 PFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATD--GMAVRKTLIPPQ---P 691 P + + T + A+ + S+P + K P T G + P P Sbjct: 3854 PETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 3913 Query: 692 PDVASPRVESSMRSTSGSPR--PAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 749 P S + R ++ +P P + + + T T SM T S+ T P Sbjct: 3914 PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTP 3973 Query: 750 PTAQQPPPTIPTMIAAASPPSQPAV-------ALSTIPGAVPITPPITTIAAAPPPSVTV 802 P P T T + PPS P A S I G IT P T + P + + Sbjct: 3974 PV----PNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTST 4029 Query: 803 GGSLSSVLGPPVPEIKVKE 821 + L P P + E Sbjct: 4030 TQHSTPALSSPHPSSRTTE 4048 Score = 68.6 bits (166), Expect = 3e-11 Identities = 119/548 (21%), Positives = 190/548 (34%), Gaps = 59/548 (10%) Query: 274 QSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQ 333 Q+ TT+ A+ ++ T V+T+TA T ++ S+ T S + + + Sbjct: 3579 QTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS-SKATSSSSPRTATTLPVL 3637 Query: 334 RPAQSRDVTTRITLPSHPALGT----PKQQLHTMA-QKTIFSTGTPVAAATVAPILATNT 388 ++ T T LGT P+Q MA TI + TP T + +L T Sbjct: 3638 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHT-STVLTT-- 3694 Query: 389 IPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH---TSPRI 445 ATT + S P+ST T + + + A T + P A T T P Sbjct: 3695 --KATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPST 3752 Query: 446 QPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT 505 S S RA+ + + T + P+V + + + P +A L A T Sbjct: 3753 TATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRST 3811 Query: 506 PITSSVSTIRQYPVSA-----------QAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 T + +++ P S+ P + ++ T TVH + + T + Sbjct: 3812 ATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3871 Query: 555 ARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAP----MGTQ 610 A G P ST GT P T +ATP ++ G P T Sbjct: 3872 A---TGSVATPSSTP-------GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTT 3921 Query: 611 QPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSI 670 P G T G T A ++ TTV + S++ G++ P + Sbjct: 3922 TPTTRGSTVTPSSIPGTTHTATVLTT------TTTTVATGSMATPSSSTQTSGTTHTPPV 3975 Query: 671 LRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVT 730 T G + +PP P S+ G+ + H AT T Sbjct: 3976 PNTTATTHGRS-----LPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS-HTPAATTST 4029 Query: 731 VSMET--VSNQNNDQPTIAVPPTAQQPPP-----TIPTMIAAASPPSQPAVALSTIPGAV 783 T +S+ + T PP+ P T T A ++ + L + P + Sbjct: 4030 TQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSA 4089 Query: 784 PITPPITT 791 PIT +TT Sbjct: 4090 PITTVVTT 4097 Score = 62.4 bits (150), Expect = 2e-09 Identities = 142/596 (23%), Positives = 202/596 (33%), Gaps = 102/596 (17%) Query: 251 PTSQLPNAATAQPAVQHIIHQPIQS----RPPVTTSNAIPPAVVATVSATRAQSPVITTT 306 PT++L A T QP S R P ++ A+P S + TT Sbjct: 2305 PTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATT 2364 Query: 307 AAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP-ALGTPK-QQLHTMA 364 T + + PT+ P A S + TR LP +LGT + Q T+A Sbjct: 2365 GGPTTPAGSTEPTV-----PGVATST--------LPTRSALPGTTGSLGTWRPSQPPTLA 2411 Query: 365 QKTIF-STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV 423 T+ S P A+ A T + T +S +QA TST T T S T Sbjct: 2412 PTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT---MSPLTNT 2468 Query: 424 TTSNIPVAKVVPQQITHTSPRIQ------PDYPA--------ERSSLIPISGHRASPNPV 469 TTS Q T P+ + D+P E I +G + P Sbjct: 2469 TTS---------QGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPK 2519 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT 529 ++E R++N P V + +T S+ T N T Sbjct: 2520 SIECRAENYPEVSID-----------------QVGQVLTCSLET------GLTCKNEDQT 2556 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQ 589 + + + N L D SH PA ST P GT I P T Sbjct: 2557 GRFNM----CFNYNVRVLCCDDYSHCPST----PATSSTATPSSTP-GTTWILTKPTTT- 2606 Query: 590 GIHSATPINTQGLQPAPMGTQQ--PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTV 647 AT + G P T + P P+ T+ + A P S+P +A Sbjct: 2607 ----ATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALR 2662 Query: 648 VQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTS 707 + +A++ P SS + R T A T P P+ A + +T+ Sbjct: 2663 STATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT 2722 Query: 708 GSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAAS 767 + A P S + T T + T + + P TA PP I T + Sbjct: 2723 TGATGSVATPSS----TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTT 2778 Query: 768 PPSQPAVALSTIPG----AVPITPPITTIA----AAPPPSVTVGGSLSSVLGPPVP 815 S V S+IPG A +T TT+A A P S G+ + PPVP Sbjct: 2779 RGS--TVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT---PPVP 2829 Score = 58.5 bits (140), Expect = 3e-08 Identities = 139/659 (21%), Positives = 215/659 (32%), Gaps = 87/659 (13%) Query: 243 SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP---PAVVATVSATRAQ 299 S TV PT A++ Q + P VT+S A P P + A R+ Sbjct: 4254 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST 4313 Query: 300 SPVITTTAAHATDSALSRPT---LSIQHPPSAAISIQRPAQSRDV--------TTRITLP 348 + T T+ A S+ T LS P+A +S P+ + + TT T Sbjct: 4314 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTR 4373 Query: 349 SHPALGTPKQQ---LHTMAQKTIFSTG-------TPVAAATVAPILATNTIPSATTAGSV 398 + ++ TP HT T +TG +P A T ++T T P TT+GS Sbjct: 4374 ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTP--TTSGST 4431 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T T TV + ++ A + P + THT P SL P Sbjct: 4432 VTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP 4491 Query: 459 ISGHR-----ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVST 513 S H S + T PS ++ P+A TP SS Sbjct: 4492 SSPHTVRTAWTSATSGTLGTTHITEPSTGT-------SHTPAATTGTTQHSTPALSSPHP 4544 Query: 514 IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQP 573 + S +P + T +T P + T + API+T Sbjct: 4545 SSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTS----APITT----- 4595 Query: 574 APIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANP 633 + T G +P ++ + + P+ P P G + T + + A G + P Sbjct: 4596 --VVTTGCEPQCAWSEWLDYSYPM------PGPSG-----GDFDTYSNIRAAGGAVCEQP 4642 Query: 634 ISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIP----P 689 + A + Q + + K +R P Sbjct: 4643 LGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCP 4702 Query: 690 QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQN-NDQPTIAV 748 P +S + SS T+ I + T T + T S + P A Sbjct: 4703 STPATSSTAMPSSTPGTTW------------ILTELTTTATTTASTGSTATPSSTPGTAP 4750 Query: 749 PPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSS 808 PP P T PT ++ + S +T+P T + P PS T+G + Sbjct: 4751 PPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTT--- 4807 Query: 809 VLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 867 +PE + V M + P S T+TV L A +S P ++P Sbjct: 4808 ---GTLPE-QTTTPVATMSTIHPSSTPETTHTSTV---LTTKATTTRATSSTSTPSSTP 4859 Score = 58.2 bits (139), Expect = 4e-08 Identities = 101/434 (23%), Positives = 149/434 (34%), Gaps = 62/434 (14%) Query: 39 STGLSQAPSQIANSGSAG--LINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 STG + PS + L +PA T S + + S+ ++ L S K Sbjct: 4735 STGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 4794 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 V P P + +T P T P A ++ P S E T + A Sbjct: 4795 SVTPIPSSTLGTT-----GTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRAT 4849 Query: 157 APPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRS 216 + ST S P +T ++ A+ P AT S G L + TT + S Sbjct: 4850 SSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGS 4909 Query: 217 NA-----PGP------PLHIGASHLPRGAAAAAVMSSSKV------TTVLRPT------- 252 A PG P +P G+ A A + + TT PT Sbjct: 4910 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 4969 Query: 253 -SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHAT 311 S P ATA PA++ + P T+ AIP + + T +Q+ T T + AT Sbjct: 4970 PSSSPGTATALPALRSTA-----TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT 5024 Query: 312 DSALSRP----------------TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGT 355 S+ T S+ P S + TT T + GT Sbjct: 5025 PSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT 5084 Query: 356 ---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMT 412 P TI ++ TP T + T T+ AT + T P+ST+ T Sbjct: 5085 ALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNS-----TATPSSTLGTTR 5139 Query: 413 VPSHSSHATAVTTS 426 + + + TA TT+ Sbjct: 5140 ILTELT-TTATTTA 5152 Score = 55.8 bits (133), Expect = 2e-07 Identities = 179/828 (21%), Positives = 267/828 (32%), Gaps = 106/828 (12%) Query: 39 STGLSQAPSQIANSGSAG--LINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 +TG + PS + L + A T S + + S+ ++ L S K Sbjct: 3588 TTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 3647 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 P P + +T P T P A ++ P S E + ++ Sbjct: 3648 SFTPIPSFTLGTT-----GTLPEQTTTPMATMSTIHPSSTPE---TTHTSTVLTTKATTT 3699 Query: 157 APPSTLSLPPKVPGQVTVTME---SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSI 213 S++S P PG + E ++ A+ P AT S G L TT Sbjct: 3700 RATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVP 3759 Query: 214 IRSNAPGPPLHIGASHLP--RGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 S A A L A + SS+ T S P ATA PA++ Sbjct: 3760 TGSTATASSTRATAGTLKVLTSTATTPTVISSRATP-----SSSPGTATALPALRSTA-- 3812 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 + P T+ AIP + + T +Q+ T T + AT S+ + Sbjct: 3813 ---TTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPE-----------TVH 3858 Query: 332 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTG-------TPVAAATVAPIL 384 + TTR T TP HT T +TG +P A T + Sbjct: 3859 TSTVLTTTTTTTRATGSVATPSSTPGTA-HTTKVPTTTTTGFTATPSSSPGTALTPPVWI 3917 Query: 385 ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPR 444 +T T P TT GS + T T TV + ++ A + P + THT P Sbjct: 3918 STTTTP--TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV 3975 Query: 445 IQPDYPAERSSLIPISGHR-----ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPL 499 SL P S H S + T PS + ++ P+A Sbjct: 3976 PNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST-------VTSHTPAATTS 4028 Query: 500 AAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQ 559 TP SS + S +P + T +T P + T + Sbjct: 4029 TTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTS 4088 Query: 560 GIQPAPIS---TQGIQPAPIGTPGIQ---PAPLGTQGIHSATPINTQGLQPA----PMGT 609 API+ T G +P + + P P G G T N + A P+G Sbjct: 4089 ----APITTVVTTGCEPQCAWSEWLDYSYPMP-GPSGGDFDTYSNIRAAGGAVCEQPLGL 4143 Query: 610 Q---QPQPE------GKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 + Q QP G+ L G F V + + P Sbjct: 4144 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTP 4203 Query: 661 AQGSSPRPS-------ILRK--KPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPR 711 A S+ PS IL K AT + T P P E S +T P Sbjct: 4204 ATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPT 4263 Query: 712 PAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQ 771 + A S + AT T + T + + A P ++ +P + + A+ P+ Sbjct: 4264 GSTATASS----TQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT- 4318 Query: 772 PAVALSTIPGA---------VPITPPITTIAAAPPPSVTVGGSLSSVL 810 A + + IP + T P T++ A P S S+VL Sbjct: 4319 -ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVL 4365 Score = 52.4 bits (124), Expect = 2e-06 Identities = 94/443 (21%), Positives = 141/443 (31%), Gaps = 53/443 (11%) Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 H + ST TP + IL T +ATT S T P+ST T + + S Sbjct: 4198 HCPSTPATSSTATPSSTPGTTWIL-TKLTTTATTTESTGSTATPSSTPGTTWILTEPSTT 4256 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 VT A Q T +P + S +P + + + P Sbjct: 4257 ATVTVPTGSTATASSTQATAGTPHV--------------STTATTPTVTSSKATPFSSPG 4302 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPI-TSSVSTIRQYPVSAQAPNSAITAQTGVGVAST 539 LP +A A ++T I +SS+ T P + ++ T T Sbjct: 4303 TATA----LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 4358 Query: 540 VHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT 599 H + + T + A G P ST G T P T + TP ++ Sbjct: 4359 AHTSTVLTTTATTTRAT---GSVATPSSTPG-------TAHTTKVPTTTTTGFTVTPSSS 4408 Query: 600 QGLQPAP----MGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSA 655 G P T P G T G T P TTV + Sbjct: 4409 PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTT------HTPTVLTTTTTTVATGSMATP 4462 Query: 656 STNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGA 715 S++ G++ P + T G + + P P S+ T G+ Sbjct: 4463 SSSTQTSGTTHTPPVPNTTATTHGRS-----LSPSSPHTVRTAWTSATSGTLGTTHITEP 4517 Query: 716 KPKSEIHVSMATPVTVSMET--VSNQNNDQPTIAVPPTAQQPPP-----TIPTMIAAASP 768 + H AT T T +S+ + T PP+ P T T A Sbjct: 4518 STGTS-HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPS 4576 Query: 769 PSQPAVALSTIPGAVPITPPITT 791 ++ + L + P + PIT +TT Sbjct: 4577 KTRTSTLLPSSPTSAPITTVVTT 4599 Score = 48.5 bits (114), Expect = 3e-05 Identities = 100/430 (23%), Positives = 141/430 (32%), Gaps = 97/430 (22%) Query: 373 TPVAAATVAPI-------LATNTIPSATTAGSVSHTQAPT------------STIVTMTV 413 TP ++T P + T +ATT S T P+ ST T+TV Sbjct: 3055 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 3114 Query: 414 PSHSSH--------------ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 P+ S+ +T TT + +K P +SP PA RS+ Sbjct: 3115 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP----FSSPGTATALPALRSTATTP 3170 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS---------S 510 + + P + + R S + T PS+ P HT T +T+ S Sbjct: 3171 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGS 3230 Query: 511 VSTIRQYPVSAQAPNSAITAQTGVGVA-----STVHLNPMQLMTVDASHAR-------HI 558 V+T P +A T TG T P+ + T R I Sbjct: 3231 VATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSI 3290 Query: 559 QGIQPAP----ISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT------QGLQPAPMG 608 G P +T + + TP GT H+ NT + L P+ Sbjct: 3291 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGT--THTPPVPNTTATTHGRSLSPSSPH 3348 Query: 609 TQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRP 668 T + TS + G T + P S S PAATT HS A SSP P Sbjct: 3349 TVRTAWTSATSGTL---GTTHITEP-STGTSHTPAATTGTTQHSTPAL-------SSPHP 3397 Query: 669 SILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTS----GSPRPAGAKPKSEIHVS 724 S R T PP P ++ R+T+ R + P S Sbjct: 3398 S------------SRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAP 3445 Query: 725 MATPVTVSME 734 + T VT+ E Sbjct: 3446 ITTVVTMGCE 3455 Score = 48.5 bits (114), Expect = 3e-05 Identities = 104/428 (24%), Positives = 142/428 (33%), Gaps = 86/428 (20%) Query: 342 TTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401 TT T S + TP ST T AT T+P+ +TA + S T Sbjct: 4226 TTATTTESTGSTATPS------------STPGTTWILTEPSTTATVTVPTGSTA-TASST 4272 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 QA T H S T TT + +K P +SP PA RS+ + Sbjct: 4273 QATAGT-------PHVS--TTATTPTVTSSKATP----FSSPGTATALPALRSTATTPTA 4319 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIR---QYP 518 + P + + R S + T PS+ P AHT T +T++ +T R Sbjct: 4320 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVA 4379 Query: 519 VSAQAPNSAITAQ----TGVGVASTVHLNPMQLMT----VDASHARHIQGIQPAPISTQG 570 + P +A T + T G T +P T + + G P S G Sbjct: 4380 TPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 4439 Query: 571 IQPAP--------------IGTPGIQPAPLGTQGIHSATPINT------QGLQPAPMGTQ 610 P + TP GT H+ NT + L P+ T Sbjct: 4440 TTHTPTVLTTTTTTVATGSMATPSSSTQTSGT--THTPPVPNTTATTHGRSLSPSSPHTV 4497 Query: 611 QPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSI 670 + TS + G T + P S S PAATT HS A SSP PS Sbjct: 4498 RTAWTSATSGTL---GTTHITEP-STGTSHTPAATTGTTQHSTPAL-------SSPHPS- 4545 Query: 671 LRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTS----GSPRPAGAKPKSEIHVSMA 726 R T PP P ++ R+T+ R + P S + Sbjct: 4546 -----------SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPIT 4594 Query: 727 TPVTVSME 734 T VT E Sbjct: 4595 TVVTTGCE 4602 Score = 36.6 bits (83), Expect = 0.13 Identities = 46/198 (23%), Positives = 69/198 (34%), Gaps = 21/198 (10%) Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPMGTQQP-----QPEGKTSAVVLADGATIVANPI 634 G P T + +AT TQ L P T P P T+ L++G T + Sbjct: 2298 GRATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLT--SPRY 2355 Query: 635 SNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDV 694 ++ A S + A + P S L P T G T P QPP + Sbjct: 2356 TSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSAL---PGTTGSL--GTWRPSQPPTL 2410 Query: 695 ASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 754 A + +S +G+ A +P + S+A +T + T Q + P T Sbjct: 2411 APTTMATSRARPTGTASTASKEP---LTTSLAPTLTSELST------SQAETSTPRTETT 2461 Query: 755 PPPTIPTMIAAASPPSQP 772 P T + + QP Sbjct: 2462 MSPLTNTTTSQGTTRCQP 2479 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 82.8 bits (203), Expect = 2e-15 Identities = 217/1003 (21%), Positives = 337/1003 (33%), Gaps = 168/1003 (16%) Query: 5 RHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATV 64 R Q GE E GG + Q +S P G + L S SGS Sbjct: 944 RDTQRGEPE-----GGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGS---------- 988 Query: 65 NDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAP 124 GR S VS R H + + ++ +R +V A P T P Sbjct: 989 -QSGGRGSPVSPRRHQKGLLNCKM-PPAEKASRIRAAEKVSRGDQESPDACLPP---TVP 1043 Query: 125 PAHLTPAVPL-SFSEGLMKPPP--KPTMPS-RPI-----------APAPPSTLSLPPKVP 169 A P PL S S+ + PPP P +PS +P AP P + L P P Sbjct: 1044 EAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHP 1103 Query: 170 GQVTVTMESS----IPQASAIPV---ATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPP 222 T +SS P SA P +T + Q P + S +++ P P Sbjct: 1104 KPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVP 1163 Query: 223 LHIGASHLPRGAAAAAVMSSSKVTTVLR----------PTSQLPNAATAQPAVQHIIHQP 272 A L + ++S + V R P + +P A QP+ +P Sbjct: 1164 T---APELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTS--TDRP 1218 Query: 273 IQSRPP------------VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL 320 + S P V T + P +T PV + AT +R ++ Sbjct: 1219 VTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSV 1278 Query: 321 SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT-IFSTGTPVAAAT 379 P RP+ S D TPK T +T + S TP Sbjct: 1279 KTPEPVVPTAPELRPSTSTDRPV-----------TPKPTSRTTRSRTNMSSVKTPETVVP 1327 Query: 380 VAPILATNTI--------PSATTAGS---VSHTQAPTSTI-VTMTVPSHSSHATAVTTSN 427 AP L +T P++ T S +S + P ST+ + +P +S VT Sbjct: 1328 TAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPE- 1386 Query: 428 IPVAKV-----------VPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRS- 475 P ++ P+ + T+P+++P ++ +P P + TR Sbjct: 1387 -PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQP---------VTPEPTSQATRGR 1436 Query: 476 DNRPSVPVQFQYFLPTYP---PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA-- 530 NR SV + +PT P PS T P TS + R S + P + + Sbjct: 1437 TNRSSVKTP-ETVVPTAPELQPSTSTDQPVTPEP-TSQATRGRTDRSSVKTPETVVPTAP 1494 Query: 531 --QTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPL-- 586 Q V P T + ++ + + +QP+ + P P Sbjct: 1495 ELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSR 1554 Query: 587 GTQGIHSATPINT--------QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPF 638 T+G + + + T LQP+ Q PE + A + V P Sbjct: 1555 ATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTP----- 1609 Query: 639 SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVAS-- 696 P T + H + ST+ P P + + AT R ++ P+P + A+ Sbjct: 1610 --EPVVPTAPEPH-PTTSTDQPV-----TPKLTSR--ATRRKTNRSSVKTPKPVEPAASD 1659 Query: 697 --PRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 754 P + T + G A PV + E S DQP + P Sbjct: 1660 LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQP---ISPEPIT 1716 Query: 755 PPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV 814 P I AA +P S A + P + P+ P +V SL+++ P Sbjct: 1717 QPSCIKRQRAAGNPGSL-AAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPAS 1775 Query: 815 PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL---ALLANNLSMPTSDLPPGASPRKKP 871 P++ +E + V P + +P L A + S+ T D PP ++ Sbjct: 1776 PQL-----LETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRG 1830 Query: 872 RKQQH--VISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPP 912 Q +I EE D E +++ T K K ++ + P Sbjct: 1831 EVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEP 1873 >gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] Length = 1073 Score = 81.6 bits (200), Expect = 4e-15 Identities = 186/919 (20%), Positives = 337/919 (36%), Gaps = 120/919 (13%) Query: 9 AGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDES 68 A + A G G G SS+ FP PS L Q P A+S S P ++N S Sbjct: 38 ASALNAAGTGVGSNAT---SSEDFP---PPS--LLQPPPPAASSTSGPQPPPPQSLNLLS 89 Query: 69 GRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHL 128 + + ++ + ++ + V P +S+++++A T +H Sbjct: 90 QAQLQA---QPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHT 146 Query: 129 TPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLS--LPPKVPGQVTVTMES-------S 179 LS SE L + T P + TL+ + PG V+ Sbjct: 147 ED---LSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPH 203 Query: 180 IPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAV 239 +PQ + + I+G HP +LHH + + + + + ++ + G ++ V Sbjct: 204 LPQQNVV----INGN-AHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPV 258 Query: 240 M------SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 SS T + PTS + ++ + + ++ R P TT +V T Sbjct: 259 SRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNM-------RAPSTTGGIGINSVTGTS 311 Query: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353 + + + + T S L +S + PSAA P + V I Sbjct: 312 TVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGT 371 Query: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV 413 + + ++ TG V++ P + T+ S + T Sbjct: 372 ISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYE 431 Query: 414 PSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMET 473 ++ AT N V V I TS R + SS+ +S + S M Sbjct: 432 KENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEM-- 489 Query: 474 RSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTG 533 P+V VQ Q P V T++Q + P S Sbjct: 490 ---GAPTVVVQQQQ---------QQQQQQQQQPALQGV-TLQQMDFGSTGPQSIPAVSIP 536 Query: 534 VGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHS 593 ++ + ++ +QL + + S+ + QG+QP P+ Q GIQP+P+ G+ S Sbjct: 537 QSISQS-QISQVQLQSQELSYQQK-QGLQPVPL-----QATMSAATGIQPSPVNVVGVTS 589 Query: 594 ATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAP----------- 642 A G QP+ QPQ +A P+ P AP Sbjct: 590 AL-----GQQPSISSLAQPQLPYSQAAP-----------PVQTPLPGAPPPQQLQYGQQQ 633 Query: 643 --AATTVVQTHSQSASTNAPAQGSSPRP----SILRKKPATDGMAVRKTLIPPQPPDVAS 696 +T + H +S + N ++ +P ++ +P++ G+ T+IP VA Sbjct: 634 PMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIP-----VAQ 688 Query: 697 PR-VESSMRSTSGSPRPAGA--KPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQ 753 P+ ++ ++ T+ +PAGA +P + +++ T S Q + PT P+ Q Sbjct: 689 PQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQ 748 Query: 754 QPPPTIPTMIAAASPPSQPAVALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLG 811 P P++I +PPS +P A I + T A + P + + S + Sbjct: 749 VP----PSVIQQGAPPSS-----QVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTV 799 Query: 812 PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKP 871 PP P + VEP+ +P +++ + S+++ + S S +P + P Sbjct: 800 PPQP-----QGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPP 854 Query: 872 RKQQHVISTEEGDMMETNS 890 + +T+ G+++++ S Sbjct: 855 QNIAQTPATQNGNLVQSVS 873 Score = 48.1 bits (113), Expect = 4e-05 Identities = 94/425 (22%), Positives = 157/425 (36%), Gaps = 53/425 (12%) Query: 271 QPIQSRPPVTTSNAIPPAVVATVSATRA--QSPVITTTAAHATDSALSRPTLSIQHPPSA 328 QP+ + ++ + I P+ V V T A Q P I++ A + + P + P + Sbjct: 563 QPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAP 622 Query: 329 AISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQ----KTIFSTGTPVAA-----AT 379 + Q + + + P H T + Q +T S+G P +A T Sbjct: 623 PPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTT 682 Query: 380 VAPI---------LATNTIPSATTAGSVSHT-QAPTSTIVTMTVPSHSSHATAVTTSNIP 429 V P+ + +P+ SV QAP + VP+ S A +NIP Sbjct: 683 VIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAA---VSAVPTGSQIANIGQQANIP 739 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQF---- 485 A V Q T P + S ++P + + + + PS+P Q Sbjct: 740 TA--VQQPSTQVPPSVIQQGAPPSSQVVP-----PAQTGIIHQGVQTSAPSLPQQLVIAS 792 Query: 486 QYFLPTYPP---SAYPLA---AHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVAST 539 Q L T PP P+A P SS+ + V++Q + T +G+ A T Sbjct: 793 QSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSS---TGPSGMPSAPT 849 Query: 540 VHLNPMQLMTVDAS-HARHIQGI-QPAPISTQG----IQPAPIGTPGIQPAPLGTQGIHS 593 + P + A+ + +Q + QP I+T Q P+ + L Q I S Sbjct: 850 NLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSL-AQAIGS 908 Query: 594 ATPINTQGLQPAPMGTQQ--PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTH 651 + +P+ +G Q G SAV +++ A+ P P T +V Sbjct: 909 QIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGE 968 Query: 652 SQSAS 656 +S+S Sbjct: 969 DESSS 973 Score = 36.2 bits (82), Expect = 0.17 Identities = 33/136 (24%), Positives = 53/136 (38%), Gaps = 9/136 (6%) Query: 614 PEGKTSAVVLAD-GATIVANPISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671 PE +A AD A +A+P P + + + + +NA + P PS+L Sbjct: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLL 64 Query: 672 RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGA--KPKSEIHVSMATPV 729 + P + PQPP S + S + + P G K KS ++ TP Sbjct: 65 QPPPPA-----ASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPA 119 Query: 730 TVSMETVSNQNNDQPT 745 +S SN + + T Sbjct: 120 QISASISSNNSIAEDT 135 Score = 35.8 bits (81), Expect = 0.23 Identities = 68/315 (21%), Positives = 109/315 (34%), Gaps = 48/315 (15%) Query: 29 SQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVS---AREHMSSSSS 85 SQ P + P G + P Q+ G P + G V+ A E++ Sbjct: 608 SQAAPPVQTPLPG-APPPQQL----QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPI 662 Query: 86 LQSREEKQEP----------VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS 135 LQ+ +P V+ PQ L A P + P PA + Sbjct: 663 LQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSA 722 Query: 136 FSEGLM--------KPPPKPTMPSRPIAP------APPSTLSLPPKVPGQVTVTMESSIP 181 G P PS + P APPS+ +PP G + +++S P Sbjct: 723 VPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAP 782 Query: 182 QASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMS 241 ++P + Q ++T Q + A G I + LP ++ + S Sbjct: 783 ---SLPQQLVIASQSS------LLTVPPQPQGVEPVAQG----IVSQQLPAVSSLPSA-S 828 Query: 242 SSKVTTVLRPT--SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQ 299 S VT+ + T S +P+A T Q+I P + S + PP + + AQ Sbjct: 829 SISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQ 888 Query: 300 SPVITTTAAHATDSA 314 +++T A A Sbjct: 889 QIPLSSTQFSAQSLA 903 >gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] Length = 1486 Score = 80.5 bits (197), Expect = 8e-15 Identities = 163/811 (20%), Positives = 285/811 (35%), Gaps = 94/811 (11%) Query: 59 NPAATVNDESGRDS-EVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASAT 117 +P +TV D + + + S +S+ +SL P +++T ++S Sbjct: 339 SPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISS-- 396 Query: 118 PVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTME 177 H TP+ S + P S PS + P+ T T Sbjct: 397 ---------HSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHST--PRFTSSFTNTKT 445 Query: 178 SSIPQASAIPVATISGQQGH--PSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAA 235 +S S + T + H PS I TT RS SH R Sbjct: 446 TSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFT 505 Query: 236 AAAVMSSSKVTTVLRPTSQLPNAATAQ---PAVQHII---HQPIQSRPPVT-------TS 282 ++ + + + TS + T P+ I P+ S P +T T+ Sbjct: 506 SSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTT 565 Query: 283 NAIPPAVVATVSATRAQSP---------VITTTAAHATDSALSRPTLSIQHPPSAAISIQ 333 + I P + ++++ T S T T + +T S S S + AI+ Sbjct: 566 SHITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSH 625 Query: 334 RPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN--TIPS 391 VT PS + P L T+ ++ T T + T P + T+ T+P+ Sbjct: 626 FTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSV-GTSTSLTTTTDFPSIPTDISTLPT 684 Query: 392 AT--TAGSVSHTQAPTSTIVTMTVPSHSS-HATAVTTSNIPVAK------VVPQQITHTS 442 T + S S TS++V T P+ S+ T T N P++ V+P+ T T Sbjct: 685 RTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTP 744 Query: 443 PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY--PLA 500 P L +G + SP P + S + + L T PS + Sbjct: 745 P-----------VLTSATGTQTSPAPTTVTFGSTDSSTST------LHTLTPSTALSTIV 787 Query: 501 AHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGV-------GVASTVHLNPMQLMTVDAS 553 + + PI S+ S+ Q S + +++T+ + G ST + + +S Sbjct: 788 STSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSS 847 Query: 554 HARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ 613 I P+ S + I + P T+ + SA+ L + + Sbjct: 848 TPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSST 907 Query: 614 PEGKTSAVVLADGATIVANPISNP------FSAAPAATT--VVQTHSQSASTNAPAQGSS 665 T+A+ + ++ P + P + PA+ T V+ + +T+ P + Sbjct: 908 SSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLT 967 Query: 666 PRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSM 725 P ++++ TL P ESS+ + S G P + + S Sbjct: 968 VFPFTTEMVTCPTSISIQTTLTTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTST 1027 Query: 726 ATPVTVSMETVSNQNN---DQPTIAVPPTAQQPPPTIPTMIAAASP---PSQPAVALSTI 779 P + + +SN + P ++ P +P ++PT++ +S PS P S Sbjct: 1028 RLPTSETW--LSNSSVIPLPLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSET 1085 Query: 780 PGAVPITPPITTIAAAPPPSVTVGGSLSSVL 810 P A TP TT+ + +T + S L Sbjct: 1086 PVATTQTP--TTLTSRRTTRITSQMTTQSTL 1114 Score = 73.9 bits (180), Expect = 7e-13 Identities = 172/842 (20%), Positives = 309/842 (36%), Gaps = 103/842 (12%) Query: 74 VSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVT----------A 123 V++ ++SS + + +P + S + S+TPV T Sbjct: 253 VTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTT 312 Query: 124 PPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQA 183 P + L +P + S P + T P+ P + ST + T++ E+S+P Sbjct: 313 PLSTLVTTLPTTISRST--PTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPT 370 Query: 184 SAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSS 243 S +++ + + + +++TT ++S + P ++ + + +S Sbjct: 371 S----SSLPTTETATTPMTNLVTTTTEIS-----SHSTPSFSSSTIYSTVTSHSTPRFTS 421 Query: 244 KVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI---PPAVVATVSATR--- 297 +TT P+ P ++ + H+ +TT+ P+ ++++ T Sbjct: 422 SITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTS 481 Query: 298 ------AQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP 351 S T T +H T S S T + + S S + + T+ T Sbjct: 482 HSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTT-SFTSSITTTETTSHSTPSFSS 540 Query: 352 ALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM 411 ++ T + LH+ T + T T + + ++ T T+ + T + T+T T Sbjct: 541 SITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTS 600 Query: 412 -TVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRA-SPNPV 469 + PS SS T S A + T+ P P+ S+ IP + R +P+ V Sbjct: 601 ESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSV 660 Query: 470 AME---TRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNS 526 T + + PS+P + T P T T I SS +I+ S+ + Sbjct: 661 GTSTSLTTTTDFPSIPTD----ISTLP---------TRTHIISSSPSIQSTETSSLVGTT 707 Query: 527 AITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPL 586 + T T V T+ + T +S + I I P T + + GT PAP Sbjct: 708 SPTMST---VRMTLRITE---NTPISSFSTSIVVIPETPTQTPPVLTSATGTQ-TSPAPT 760 Query: 587 ---------GTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNP 637 T +H+ TP + L +Q P P +S T+ P + Sbjct: 761 TVTFGSTDSSTSTLHTLTP--STALSTIVSTSQVPIPSTHSS--------TLQTTPSTPS 810 Query: 638 FSAAPAATTVVQTHS---QSASTNAPAQG------SSPRPSILRKKPATDGMA-VRKTLI 687 + +T+ T S S STNA SS I+ P++ + V T I Sbjct: 811 LQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTI 870 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA 747 P +SP + S+ GS G S + + + S+ T + I+ Sbjct: 871 HSVP---SSPYIFST--ENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYIS 925 Query: 748 VPPTAQQPPPTIPTMIAAASPPSQPAVAL-----STIPGAVPITP-PITTIAAAPPPSVT 801 +P T P P T+ + P+ P V + +T P P+T P TT P S++ Sbjct: 926 LPSTT--PCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSIS 983 Query: 802 VGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDL 861 + +L++ + + + + P + P TNTV S L + + S + Sbjct: 984 IQTTLTTYMDTSSMMPESESSISPNASSSTGTGTVP--TNTVFTSTRLPTSETWLSNSSV 1041 Query: 862 PP 863 P Sbjct: 1042 IP 1043 Score = 65.1 bits (157), Expect = 3e-10 Identities = 137/709 (19%), Positives = 247/709 (34%), Gaps = 96/709 (13%) Query: 196 GHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRG-----------------AAAAA 238 GH N +TT+ ++I P+ S P A Sbjct: 69 GHRENAPMTLTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYSATTEC 128 Query: 239 VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRA 298 V +S + T+ PTS T Q A ++ PVTT V +T S T Sbjct: 129 VYPTSFIITISHPTSIC--VTTTQVAFTSSYTSTPVTQKPVTT-------VTSTYSMTTT 179 Query: 299 QSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 + T++ +T +A P +++ PS+ + + +T T P P Sbjct: 180 EKGTSAMTSSPSTTTARETPIVTVT--PSSVSATDTTFHTTISSTTRTTERTPL---PTG 234 Query: 359 QLHTMAQKTIFSTGTPVAAATVAPILA----TNTIPSATTAGS----VSHTQAPTSTIVT 410 +HT T T A + +PI + TNT+ S TT S + +PT TI++ Sbjct: 235 SIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILS 294 Query: 411 MTVPSHSSHATAVTTSNIPVAKVV---PQQITHTSPRIQPDYPAERSSLIPISGHRASPN 467 T + T+ T+ P++ +V P I+ ++P + YP +S + S + + + Sbjct: 295 STPVLSTETITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYS 354 Query: 468 PVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSA 527 +M S+P PT S+ P TP+T+ V+T + + S+ Sbjct: 355 -TSMTGTLSTETSLP-------PT--SSSLPTTETATTPMTNLVTTTTEISSHSTPSFSS 404 Query: 528 ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG 587 T + V ST T SH+ S + +P Sbjct: 405 STIYSTVTSHSTPRFTSSITTTETPSHS-----TPRFTSSFTNTKTTSHRSPSFTSLITT 459 Query: 588 TQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG--------ATIVANPISNPFS 639 T+ +TP T + T TS++ + + + +N S Sbjct: 460 TETTSHSTPSFTSSITTTE--TTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHS 517 Query: 640 AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA-TDGMAVRKT-----------LI 687 +++ T + S ST + + + + L P T + KT + Sbjct: 518 TTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSIT 577 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVT-VSMETVSNQNNDQPTI 746 + ++P SS+ +T + + S I+ +++T T ++ +++ PT Sbjct: 578 TTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPT- 636 Query: 747 AVPPTAQQPPPTIPTMIAAASPPSQPAVALS--------TIPGAVPITPPITTIAAAPP- 797 P T IPT PS + S +IP + P T I ++ P Sbjct: 637 --PVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPS 694 Query: 798 ----PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 842 + ++ G+ S + +++ E + +P T T Sbjct: 695 IQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQT 743 Score = 61.6 bits (148), Expect = 4e-09 Identities = 130/606 (21%), Positives = 211/606 (34%), Gaps = 64/606 (10%) Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 T T S P S+ T + P + TT I SH Sbjct: 528 TETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTP 587 Query: 233 G--AAAAAVMSSSKVTTVLRPTSQLPNAATAQPAV-QHIIHQPIQSRPPVTTSNAIPPAV 289 G ++ ++S+ T L ++ +T+ A+ H P T +++ + Sbjct: 588 GFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDI 647 Query: 290 VATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPS 349 T T S V T+T+ T S PT P I P+ T+ + + Sbjct: 648 PTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTT 707 Query: 350 HPALGTPKQQLHTMAQKTIFSTGT-----PVAAATVAPILA----TNTIPSATTAGSVSH 400 P + T + L I S T P P+L T T P+ TT + Sbjct: 708 SPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTV-TFGS 766 Query: 401 TQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPAERSSLIPI 459 T + TST+ T+T PS ++ +T V+TS +P+ TH+S + P P+ ++SL Sbjct: 767 TDSSTSTLHTLT-PS-TALSTIVSTSQVPIPS------THSSTLQTTPSTPSLQTSLTST 818 Query: 460 SGHRA----------------------SPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY 497 S S P + + S + S+ F + + P S Y Sbjct: 819 SEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPY 878 Query: 498 PL-------AAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNP----MQ 546 A+ T P SS +T S+ +A+T T S P + Sbjct: 879 IFSTENVGSASITGFPSLSSSATTSTSSTSSSL-TTALTEITPFSYISLPSTTPCPGTIT 937 Query: 547 LMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAP 606 + V AS + P ST+ P T + P T+ + T I+ Q Sbjct: 938 ITIVPASPTDPCVEMDP---STEATSPP---TTPLTVFPFTTEMVTCPTSISIQTTLTTY 991 Query: 607 MGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSP 666 M T PE ++S A +T +N + T S S+ P G S Sbjct: 992 MDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPGVST 1051 Query: 667 RPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMA 726 P L KP++ + +T P + R + +T+ +P ++ + I M Sbjct: 1052 IP--LTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMT 1109 Query: 727 TPVTVS 732 T T++ Sbjct: 1110 TQSTLT 1115 Score = 50.4 bits (119), Expect = 9e-06 Identities = 56/258 (21%), Positives = 100/258 (38%), Gaps = 36/258 (13%) Query: 618 TSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAS-TNAPAQGSSPRPSILRKKPA 676 TS V ++ S P + P TTV T+S + + A SSP + R+ P Sbjct: 142 TSICVTTTQVAFTSSYTSTPVTQKP-VTTVTSTYSMTTTEKGTSAMTSSPSTTTARETP- 199 Query: 677 TDGMAVRKTLIPPQPPDVAS------PRVESSMRSTSGSPRPAGA----KPKSEIHVSMA 726 ++ P V++ + S+ R+T +P P G+ + + ++ Sbjct: 200 ---------IVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLK 250 Query: 727 TPVTVSMETVSNQNNDQPTIAVPPTAQQPPPT----IPTMIAAASPPSQPAVALSTIPGA 782 T VT + S+ + ++ TA QP T PT + S P ++ TI Sbjct: 251 TAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILS---STPVLSTETITSG 307 Query: 783 VPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 842 + T P++T+ P +++ S P P V + + A T T Sbjct: 308 ITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKI-------AYSTSMTGT 360 Query: 843 VSPSLALLANNLSMPTSD 860 +S +L + S+PT++ Sbjct: 361 LSTETSLPPTSSSLPTTE 378 >gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] Length = 2382 Score = 79.7 bits (195), Expect = 1e-14 Identities = 159/686 (23%), Positives = 257/686 (37%), Gaps = 100/686 (14%) Query: 239 VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPI-QSRPPVTTSNAIPPAVVATVSATR 297 + +SS + PTS L + A + I P+ +SR + S P + TV+A+ Sbjct: 1231 IPASSMPQQIGIPTSSLTQVVHS--AGRRFIVSPVPESR--LRESKVFPSEITDTVAAST 1286 Query: 298 AQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSH--PALGT 355 AQSP + + H+ S LS+Q A ++R + T SH P Sbjct: 1287 AQSPGMNLS--HSASS------LSLQQ---AFSELRRAQMTEGPNTAPPNFSHTGPTFPV 1335 Query: 356 PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV-SHTQAPTST----IVT 410 L ++A G P AA AP+ AT++ P+ + + S PT + T Sbjct: 1336 VPPFLSSIA-------GVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVAT 1388 Query: 411 MT----------VPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPIS 460 T P S + S+I + VV I+ TSP +Q P S ++ +S Sbjct: 1389 STGVVTSGGLPIPPVSESPVLSSVVSSITIPAVV--SISTTSPSLQ--VPTSTSEIV-VS 1443 Query: 461 GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVS 520 P+ T + S P S + T +SVST +P + Sbjct: 1444 STALYPSVTVSATSASAGGSTATPGPK--PPAVVSQQAAGSTTVGATLTSVSTTTSFPST 1501 Query: 521 AQAPNSAITAQTGVG-VASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A + +++ T +A TV ++ L S + AP S+ A + + Sbjct: 1502 ASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSS-PGAGVSSY 1560 Query: 580 GIQPA---PLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISN 636 QP PL + ++TPI PQ G TS +L +I P+ Sbjct: 1561 ISQPGGLHPLVIPSVIASTPI-------------LPQAAGPTSTPLLPQVPSIP--PLVQ 1605 Query: 637 PFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVAS 696 P + PA + HSQ P+P++L +P T V P P Sbjct: 1606 PVANVPAVQQTL-IHSQ------------PQPALLPNQPHTHCPEVDSDTQPKAPGIDDI 1652 Query: 697 PRVESSMRSTSGSPRPAGAKPKS---EIHVSMATPVTVSMETV----SNQNNDQPTIAVP 749 +E +RS +GA+ S E + + + VT + T S + +P Sbjct: 1653 KTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLP 1712 Query: 750 PTAQQPPPTIPTMIAAASPPSQPAVALSTI-----PGAVPITPPITTIAAAPPPSVTVGG 804 PT P T+ + P Q + +ST PG P PP+T P + G Sbjct: 1713 PT-NLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAG 1771 Query: 805 SLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 +L S PP P + + +P++ + T+SP + + + + P S P Sbjct: 1772 TLPSEQLPPFPGPSLTQSQQPLE------DLDAQLRRTLSPEMITVTSAVG-PVSMAAPT 1824 Query: 865 ASPRKKPRKQQHVISTEEGDMMETNS 890 A + Q+ V +EG ++ T+S Sbjct: 1825 AITEAGTQPQKGVSQVKEGPVLATSS 1850 Score = 58.5 bits (140), Expect = 3e-08 Identities = 194/944 (20%), Positives = 325/944 (34%), Gaps = 132/944 (13%) Query: 16 GAGGGRRLQVEMSSQQFPRLG-----APSTGL--SQAPSQI-ANSGSAGLINPAATVNDE 67 G G + +SSQQ G A STG PS + A S G+ P++ + Sbjct: 658 GQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQ 717 Query: 68 SGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAH 127 S S+ +SSS +Q +++Q + + P Q + + S + A TA P Sbjct: 718 SQGQPSSSSLTGVSSSQPIQHPQQQQG--IQQTAPPQQTVQYSLSQTSTSSEATTAQPVS 775 Query: 128 L--TPAVPLSFSEGLMKP--PPKPTMPSRPIAPAPPSTLSLPPKVPGQ-VTVTMESSIPQ 182 P V S G P P PT+ P P +P + V P Sbjct: 776 QPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPL 835 Query: 183 ASAIPVATISGQQGHPSNLHHIMTTNVQMSII----RSNAPGPPLHIGASHLPRGAAAAA 238 PV+ I P + H+ T S + + P L + +S + Sbjct: 836 LPQYPVSQI------PISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVS 889 Query: 239 VMSSSKVTTVLRPTSQLPNAA---TAQPAVQHI---IHQPIQSRPPVTTSNAI----PPA 288 + S++ T+L+P +QLP+ QPAVQ + + + P+++ + + PP Sbjct: 890 TVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPR 949 Query: 289 VVATV--SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRIT 346 + + A S + + H+T + PT + P +Q +S + Sbjct: 950 LPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGG 1009 Query: 347 LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTS 406 + + P L AQ S+ V +T + P+ A V+ TQA Sbjct: 1010 VGGQVQVSQPGGSL---AQAPTTSSQQAVLESTQG---VSQVAPAEPVA--VAQTQATQP 1061 Query: 407 TIVTMTVPS-HSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRAS 465 T + +V S HS A+ ++ N V + T+ R R S+ S H + Sbjct: 1062 TTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKR------HYRKSVRSRSRHEKT 1115 Query: 466 PNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPN 525 P N+ V+ Q L H +T ++ + P Sbjct: 1116 SRPKLRILNVSNKGDRVVECQ------------LETHNRKMVTF------KFDLDGDNPE 1157 Query: 526 SAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGI--QPAPISTQGIQPAPIGTPGIQP 583 +A+ + N L S ++ I + + ++ + P G G++ Sbjct: 1158 E---------IATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLES 1208 Query: 584 AP-LGTQGIHSATPINTQGLQPAPMGTQQPQ---PEGKTSAVVLADGATIVANPI----- 634 G + + + QP P + Q P + VV + G + +P+ Sbjct: 1209 LQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRL 1268 Query: 635 -SNPFSAAPAATTVVQTHSQSASTNAPAQGSS----PRPSILRKKPATDGMAVRKTLIPP 689 + + TV + +QS N SS S LR+ T+G Sbjct: 1269 RESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSH 1328 Query: 690 QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 749 P P V + S +G P A A T + S+ ND T + Sbjct: 1329 TGP--TFPVVPPFLSSIAGVPTTAAA--------------TAPVPATSSPPNDISTSVI- 1371 Query: 750 PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSV 809 Q T+PT A + V S G +PI PP++ S + +SS+ Sbjct: 1372 ----QSEVTVPTEEGIAGVATSTGVVTS---GGLPI-PPVS-------ESPVLSSVVSSI 1416 Query: 810 LGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT-VSPSLALLANNLSMPTSDLPPGASPR 868 P V I + P S + ++T + PS+ + A + S S PG P Sbjct: 1417 TIPAVVSISTTSP----SLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPP 1472 Query: 869 KKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPP 912 +Q +T + ++T STA L ++ S P Sbjct: 1473 AVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTP 1516 Score = 50.4 bits (119), Expect = 9e-06 Identities = 184/877 (20%), Positives = 303/877 (34%), Gaps = 206/877 (23%) Query: 16 GAGGGRRLQVEM-----SSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGR 70 G G ++L+ E +S ++G P++ L+Q + ++G +++P V + R Sbjct: 1216 GFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQV---VHSAGRRFIVSP---VPESRLR 1269 Query: 71 DSEVSARE------------------HMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHH- 111 +S+V E H +SS SLQ + + P + H Sbjct: 1270 ESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHT 1329 Query: 112 ------------AVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRP-IAPAP 158 ++A A P T + P S +++ + T+P+ IA Sbjct: 1330 GPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQS--EVTVPTEEGIAGVA 1387 Query: 159 PST-------LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM 211 ST L +PP V ++ SSI + + ++T S P++ I Sbjct: 1388 TSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEI------- 1440 Query: 212 SIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 ++ S A P + + A TS +TA P Sbjct: 1441 -VVSSTALYPSVTVSA------------------------TSASAGGSTATPG------- 1468 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 +PP S A TV AT + V TTT+ +T S LS S P+ A + Sbjct: 1469 ---PKPPAVVSQ--QAAGSTTVGAT--LTSVSTTTSFPSTASQLSIQLSSSTSTPTLAET 1521 Query: 332 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP-ILATNTIP 390 + A S D T SH + T A + S G V++ P L IP Sbjct: 1522 VVVSAHSLDKT------SHSS--TTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIP 1573 Query: 391 SATTAGSV-SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 S + + PTST + VPS V +N+P V Q + H+ P QP Sbjct: 1574 SVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPV--ANVP---AVQQTLIHSQP--QP-- 1624 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVP------VQFQYFLPTYPPSAYPLAAHT 503 +L+P H P E SD +P P + + + A H Sbjct: 1625 -----ALLPNQPHTHCP-----EVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHA 1674 Query: 504 YTPITSSV---STIRQ-YPVSAQAPNSAITAQTGVGVAST-VHLNPMQLMTVDASHARHI 558 + +S+ ST+ P +A AP+ +T+ T + T + L + L + Sbjct: 1675 SVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQV 1734 Query: 559 QGIQPAPISTQGIQPAPIGTPGIQP-------APLGTQGIHSATPINTQGLQPAPMGTQQ 611 P +T G++P GT +P P+GT+ P P P TQ Sbjct: 1735 S--TPVSTTTSGVKP---GTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQS 1789 Query: 612 PQPEGKTSAVV---LADGATIVANPISNPFSAAPAATTVVQTHSQ---SASTNAPAQGSS 665 QP A + L+ V + + AAP A T T Q S P +S Sbjct: 1790 QQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATS 1849 Query: 666 PRPSILR-----------------KKPATDGMAV-----------------RKTLIPPQP 691 + + K + D +V TL+ P+P Sbjct: 1850 SGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEP 1909 Query: 692 -----PDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMAT--------PVTVSMETVSN 738 P ++S ES+ ++T+ + +P + T V+ + + +++ Sbjct: 1910 NGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITD 1969 Query: 739 QNNDQPTIAVPPTAQQPPPTIPTMIAAASPP--SQPA 773 + P +A PP +P +I P S+P+ Sbjct: 1970 TKKEGP-VASPPFMDLEQAVLPAVIPKKEKPELSEPS 2005 Score = 49.3 bits (116), Expect = 2e-05 Identities = 116/503 (23%), Positives = 172/503 (34%), Gaps = 78/503 (15%) Query: 322 IQHPPSAAISIQRPA-QSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATV 380 I+ PSA+ I + S V+T++ P P +Q + ++ S GT + Sbjct: 603 IKQLPSASTGIPTASTTSASVSTQVE-PEEPEADQHQQLQYQQPSISVLSDGTVDSGQGS 661 Query: 381 APILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH 440 + + T + H QA + T TVP H + V + P P + Sbjct: 662 SVFTESRVSSQQTVSYGSQHEQAHS----TGTVPGHI--PSTVQAQSQPHGVYPPSSVAQ 715 Query: 441 TSPRIQPDYPAERSSLIPISGHRASPNPVAME-TRSDNRPSVPVQF---QYFLPTYPPSA 496 + QP SSL +S + +P + + P VQ+ Q + +A Sbjct: 716 GQSQGQP----SSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTA 771 Query: 497 YPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHAR 556 P++ + VS +Q PVS P I + + VA+ + P+ +H Sbjct: 772 QPVSQPQAPQVLPQVSAGKQLPVSQPVP--TIQGEPQIPVATQPSVVPVH----SGAHFL 825 Query: 557 HIQGIQPAPISTQ-GIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPE 615 + P P+ Q + PI TP + A G S+ PI G QP Sbjct: 826 PVGQPLPTPLLPQYPVSQIPISTPHVSTAQTG----FSSLPITMAA------GITQPLLT 875 Query: 616 GKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQ-----SASTNAPA--------- 661 +SA A P P P Q H Q S PA Sbjct: 876 LASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVP 935 Query: 662 --------QGSSPR-----PSILRKKPATDGMAV---RKTLIPPQP----------PDVA 695 QG PR P P+++ +V L PP P P V Sbjct: 936 LSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVV 995 Query: 696 SPRVESSMRSTSGSPRPAGAKPKSEIHVSMA-TPVTVSMETV--SNQNNDQPTIAVPPTA 752 P VES++ G G S+ S+A P T S + V S Q Q A P Sbjct: 996 QPYVESNLLVPMGG--VGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAV 1053 Query: 753 QQPPPTIPTMIAAASPPSQPAVA 775 Q T PT +A++ + VA Sbjct: 1054 AQTQATQPTTLASSVDSAHSDVA 1076 Score = 40.0 bits (92), Expect = 0.012 Identities = 65/325 (20%), Positives = 118/325 (36%), Gaps = 21/325 (6%) Query: 569 QGIQPAPIGTPGIQPAPLGTQGIHSATP----INTQGLQPAPMGTQQPQPEGKTSAVVLA 624 Q ++ + GI+ P + GI +A+ ++TQ P Q Q + + ++ + Sbjct: 591 QQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVL 650 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPR--PSILRKKPATDGMAV 682 T+ + S+ F+ + ++ ++ S A + G+ P PS ++ + G+ Sbjct: 651 SDGTVDSGQGSSVFTESRVSSQQTVSYG-SQHEQAHSTGTVPGHIPSTVQAQSQPHGVYP 709 Query: 683 RKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNND 742 ++ Q S SS+ S S + + I + TV + Sbjct: 710 PSSVAQGQSQGQPS---SSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSS 766 Query: 743 QPTIAVPPTAQQPPPTIPTMIAAAS-PPSQPAVALSTIPGAVPITPPITTIAAAPPPSVT 801 + T A P + Q P +P + A P SQP + P T P + + Sbjct: 767 EATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLP 826 Query: 802 VGGSLSSVLGP--PVPEIKV--------KEEVEPMDIMRPVSAVPPLATNTVSPSLALLA 851 VG L + L P PV +I + + + I PL T S + A + Sbjct: 827 VGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIP 886 Query: 852 NNLSMPTSDLPPGASPRKKPRKQQH 876 ++ S LP P + Q H Sbjct: 887 GVSTVVPSQLPTLLQPVTQLPSQVH 911 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 76.3 bits (186), Expect = 2e-13 Identities = 124/554 (22%), Positives = 201/554 (36%), Gaps = 56/554 (10%) Query: 332 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVA----PILATN 387 +QRP+++ V T + AL +P++ A GT V AA V IL + Sbjct: 831 LQRPSRTAAVPT-VKDALDAALPSPEEGTSIAAVPA--PEGTAVVAALVPFPHEDILVAS 887 Query: 388 TIP---SATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPR 444 + TA +VS + T VT++VP ++ A A +S A V IT Sbjct: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTA-AVAAVSSPEETAPAVAAAITQEGMS 946 Query: 445 IQPDYPAERSSL---IPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAA 501 + E ++L +PI+ +P + + P P + T A P AA Sbjct: 947 AVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAA 1006 Query: 502 HTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGI 561 +S + P +P +A+ + P + + A+ + Sbjct: 1007 VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066 Query: 562 QPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAV 621 PA + P P P +A P + PA +P +AV Sbjct: 1067 SPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124 Query: 622 VL----ADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 A A V P P APA T ++ S + + P + +SP ++ + Sbjct: 1125 PTPEEPASPAAAVPTP-EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183 Query: 678 DGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVT------- 730 AV TL P P + P + + + PA + P SE S+A V+ Sbjct: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243 Query: 731 --VSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPP 788 ++ T+ + + P P ++PT P+ PA A+S + P Sbjct: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT----PEEPASPAAAVSN------LEEP 1293 Query: 789 ITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPL--ATNTVSPS 846 + AA P P V + +SV P VP I P +AVPP+ + P Sbjct: 1294 ASPAAAVPTPEVAAIPA-ASVPTPEVPAI-------------PAAAVPPMEEVSPIGVPF 1339 Query: 847 LALLANNLSMPTSD 860 L + A+ S+P S+ Sbjct: 1340 LGVSAHTDSVPISE 1353 Score = 55.5 bits (132), Expect = 3e-07 Identities = 83/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%) Query: 59 NPAATVNDESGRDSEVSA----REHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVA 114 +PAA V S +A E S ++++ + EE P P P+ T A A Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---TSPAAA 1084 Query: 115 SATPVAVTAPPAHL-TPAVPLSFSEGLMKP--PPKPTM----PSRPIAPAPPSTLSLPPK 167 TP T+P A + TP P S + + P P P P P +PA P Sbjct: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA 1144 Query: 168 VPGQVTVTMESSIPQASAIPV--ATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 P T E S A A+P + S P+ V ++ +P Sbjct: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP------ 1198 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI 285 A+ +P AA A + PTS+ P + A S P TS Sbjct: 1199 -AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA-----------AVSNPEEPTS--- 1243 Query: 286 PPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRI 345 P A V T+ + P ++ AA T LS P S+ P + PA + + Sbjct: 1244 PAAAVPTL-----EEPT-SSAAAVLTPEELSSPAASVPTP-------EEPASPAAAVSNL 1290 Query: 346 TLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQA 403 P+ PA P ++ + ++ + P A P + + G +HT + Sbjct: 1291 EEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDS 1348 Score = 55.1 bits (131), Expect = 4e-07 Identities = 111/525 (21%), Positives = 176/525 (33%), Gaps = 89/525 (16%) Query: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVAS---AT 117 AA + D+ + + E +S +++ + E + P+P +L T Sbjct: 838 AAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVT 897 Query: 118 PVAVTAPPAHLTPAVPLSFSEGLMK----PPPKPTMPS----------RPIAPAPPSTLS 163 AV+AP PAV +S EG P+ T P+ +A P + Sbjct: 898 AAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAA 957 Query: 164 LPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRS-----NA 218 L VP +T E P+ P T+ + + + T S + Sbjct: 958 LAITVP----ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013 Query: 219 PGPPLHIGASHLPRGAAAAA------VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P + P AAA ++ V T PTS P AA P Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS--PAAAVPTP--------- 1062 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHA-------TDSALSRPTLSIQHP 325 P + + A+P T A +P T+ A A T A + PT + P Sbjct: 1063 ---EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--PEEP 1117 Query: 326 PSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILA 385 S A ++ P + + P PA P + + TP +A+ A + Sbjct: 1118 ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVP 1177 Query: 386 TNTIPSATTAGSVSHTQAPTSTIVTMTVPS--------HSSHATAVTTSNIP--VAKVVP 435 T SA+ A V+ + PTS ++ P+ +S A +V TS P +A V Sbjct: 1178 T-PAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS 1236 Query: 436 QQITHTSPR----------------IQPDYPAERSSLIPISGHRASPNPVAMETRSDNRP 479 TSP + P+ + ++ +P ASP P Sbjct: 1237 NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296 Query: 480 SVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAP 524 + V PT +A P AA TP ++ P+ +P Sbjct: 1297 AAAV------PTPEVAAIP-AASVPTPEVPAIPAAAVPPMEEVSP 1334 Score = 55.1 bits (131), Expect = 4e-07 Identities = 96/359 (26%), Positives = 128/359 (35%), Gaps = 70/359 (19%) Query: 573 PAPIGTPGIQP-APLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA 631 PAP GT + P + I A+ ++ + P+ + V T Sbjct: 864 PAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAV 923 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILR-KKPAT--DG-----MAVR 683 +S+P APA + SA G SP + L P T DG + Sbjct: 924 AAVSSPEETAPAVAAAITQEGMSA-----VAGFSPEWAALAITVPITEEDGTPEGPVTPA 978 Query: 684 KTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQ 743 T+ P+ PD A+ RV + S PA A P E S A V E S Sbjct: 979 TTVHAPEEPDTAAVRVSTPEEPAS----PAAAVPTPEEPTSPAAAVPTPEEPTS------ 1028 Query: 744 PTIAVPPTAQQPPPTIPTMIAAASP-PSQPAVALSTIPGAVPITP--PITTIAAAPPPSV 800 P A PPP PT AAA P P +P T P A TP P + AA P P Sbjct: 1029 ------PAAAVPPPEEPTSPAAAVPTPEEP-----TSPAAAVPTPEEPTSPAAAVPTPEE 1077 Query: 801 TVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSD 860 S P PE EP P +AVP T SP+ A +PT + Sbjct: 1078 PT----SPAAAVPTPE-------EPTS---PAAAVPTPEEPT-SPAAA-------VPTPE 1115 Query: 861 LPPGASPR------KKPRKQQHVISTEEGDMMETNS--TDDEKSTAKSLLVKAEKRKSP 911 P ASP ++P + T E + T +E ++A + E+ SP Sbjct: 1116 EP--ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP 1172 Score = 45.4 bits (106), Expect = 3e-04 Identities = 61/269 (22%), Positives = 98/269 (36%), Gaps = 29/269 (10%) Query: 612 PQPEGKTS--AVVLADGATIVANPISNPFSAAPAATTVVQTHSQ--SASTNAPAQGSSPR 667 P PE TS AV +G +VA + P A+ V +A+ +AP + + P Sbjct: 852 PSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPA 911 Query: 668 PSILRKKPATDGMAVRKTLIPPQP--PDVASPRVESSMRSTSG-SPRPAGAKPKSEIHVS 724 ++ +G A + P+ P VA+ + M + +G SP A ++ Sbjct: 912 VTV----SVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAA--------LA 959 Query: 725 MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP---- 780 + P+T T T+ P + P T ++ P+ PA A+ T Sbjct: 960 ITVPITEEDGTPEGPVTPATTVHAP----EEPDTAAVRVSTPEEPASPAAAVPTPEEPTS 1015 Query: 781 --GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPL 838 AVP T+ AAA PP ++V P P P + P +AVP Sbjct: 1016 PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1075 Query: 839 ATNTVSPSLALLANNLSMPTSDLPPGASP 867 T + + P + +P P Sbjct: 1076 EEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1104 >gi|148612879 polyhomeotic like 3 [Homo sapiens] Length = 995 Score = 75.1 bits (183), Expect = 3e-13 Identities = 150/703 (21%), Positives = 256/703 (36%), Gaps = 113/703 (16%) Query: 288 AVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347 AV A++S+ R P + T + S++S+ ++++ P+ A I R S + IT Sbjct: 110 AVQASLSSGR---PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQ 166 Query: 348 PS------HPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401 + P L + Q++ AQ IF+ T VAA + I ++ S++ + + Sbjct: 167 QTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQ-SDIPVVSSSSSSSCQSAATQV 225 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 Q T + V S S + +TS + + T TS +I P+ S+ S Sbjct: 226 QNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESP 285 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521 S + T S ++ P + P + L H P+ S S + + + Sbjct: 286 SLESRSTAVTRTSSIHQLIAPASYS------PIQPHSLIKHQQIPLHSPPSKVSHHQLIL 339 Query: 522 QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI-----QGIQPAPISTQGIQPAPI 576 Q I T +Q T D ++H G+ PAP + Q +PI Sbjct: 340 QQQQQQIQPIT------------LQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPI 387 Query: 577 GTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANP-IS 635 + P+PL S + + + P P P ++ +++ A I +P +S Sbjct: 388 QS---HPSPLTVSPNQSQSAQQSVVVSPPP-----PHSPSQSPTIIIHPQALIQPHPLVS 439 Query: 636 NPFSAAPAATTVVQTHSQ-SASTNAPAQGSSPRPSILRKKPATDGMAVR--KTLIPPQPP 692 + P Q +A N P+ P ++ P V + ++ P Sbjct: 440 SALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQ 499 Query: 693 DVASPR-----VESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQN---NDQP 744 +S + + S + ++ P P + P +S V QN +++ Sbjct: 500 QYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEE 559 Query: 745 TIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPI--------------- 789 A Q P T+P PP AV L P A P+ PP+ Sbjct: 560 LPAAEALVQLPFQTLP-------PPQTVAVNLQVQPPA-PVDPPVVYQVEDVCEEEMPEE 611 Query: 790 ----TTIAAAPPP------SVTVGGS---------LSSVLGPPVPEIKVKEEVEPMDIMR 830 + PPP ++TVG L V P V + P D Sbjct: 612 SDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSH 671 Query: 831 PVSAVPPLATNTVSPSLALLANNLSMPTS-----DLPPGASPRKKPRKQQHVISTEEGDM 885 PPL + P+ +N+ SM +S + PP A KP+ HVI EG + Sbjct: 672 VSVPPPPL----LLPAATTRSNSTSMHSSIPSIENKPPQAI--VKPQILTHVI---EGFV 722 Query: 886 METNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRP 928 ++ + + SLL++ +K P +D + + V V+P Sbjct: 723 IQ-EGLEPFPVSRSSLLIEQPVKKRP---LLDNQVINSVCVQP 761 Score = 38.5 bits (88), Expect = 0.035 Identities = 95/490 (19%), Positives = 180/490 (36%), Gaps = 101/490 (20%) Query: 33 PRLGAPSTGLSQAPS--QIANSGSAGLINPAATVNDES----GRDSEVSAREHMSSSSSL 86 P L + ST +++ S Q+ S I P + + + S+VS + + L Sbjct: 285 PSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLI-----L 339 Query: 87 QSREEKQEPVVVRPYPQVQMLSTH------HAVASA---------TPVAVTAPPAHLTPA 131 Q ++++ +P+ ++ Q S H H + A +P+ P ++P Sbjct: 340 QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN 399 Query: 132 VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATI 191 S + ++ PP P PS+ T+ + PQA P + Sbjct: 400 QSQSAQQSVVVSPPPPHSPSQ------------------SPTIIIH---PQALIQPHPLV 438 Query: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251 S NL T N + + N P SHLP A+ + + + ++ P Sbjct: 439 SSALQPGPNLQQ-STANQVQATAQLNLP--------SHLPLPASPVVHIGPVQQSALVSP 489 Query: 252 TSQLPNAATAQPAVQHIIHQPIQSRPPVTTS--NAIPPAVVATVSATR------------ 297 Q+ + + Q + PI S P ++TS IPP + ++ + + Sbjct: 490 GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVL 549 Query: 298 AQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS--IQRPA--------QSRDVTTR--- 344 Q+ +++ A ++ + P ++ P + A++ +Q PA Q DV Sbjct: 550 VQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMP 609 Query: 345 ------ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 + + P T T+ + ++ P+ P +A+ + + Sbjct: 610 EESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDP 669 Query: 399 SHTQAPTSTIV----TMTVPSHSSHATAVTTSNIPVAKVV-PQQITHT------SPRIQP 447 SH P ++ T S S H++ + N P +V PQ +TH ++P Sbjct: 670 SHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEP 729 Query: 448 DYPAERSSLI 457 +P RSSL+ Sbjct: 730 -FPVSRSSLL 738 >gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial [Homo sapiens] Length = 909 Score = 73.2 bits (178), Expect = 1e-12 Identities = 157/788 (19%), Positives = 275/788 (34%), Gaps = 107/788 (13%) Query: 108 STHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPK 167 ++H + T + T P+H TP+ S + P+ S I ++ S P Sbjct: 75 TSHSTPSYTTSITTTETPSHSTPSYTTSITTTETPSHSTPSFTS-SITTTETTSHSTPSF 133 Query: 168 VPG-QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 + T T S P ++ T + PS + I TT S S + Sbjct: 134 TSSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTET 193 Query: 227 ASHLPRGAAAAAVMS----------SSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSR 276 SH G ++ + +S +TT + P+ ++ + H S Sbjct: 194 TSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSITTSETPSHSTPSST 253 Query: 277 PPVTTSNAI---PPAVVATVSATR---------AQSPVITTTAAHATDSALSRPTLSIQH 324 +TT+ P+ ++++ T S T T +H T S S T + + Sbjct: 254 SLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETTSHNTRSFTSSITTTETN 313 Query: 325 PPSA-----------AISIQRPAQSRDVTTRIT------------------LPSHPALGT 355 S S P+ S +TT T PS + Sbjct: 314 SHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPVTPSSLSTDI 373 Query: 356 PKQQLHTMAQKTIFSTGTPVAAATVAPILAT--NTIPSAT--TAGSVSHTQAPTSTIVTM 411 P L T+ ++ T T + T P + T +T+P+ T + S S TS++V Sbjct: 374 PTTSLRTLTPSSV-GTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGT 432 Query: 412 TVPSHSS-HATAVTTSNIPVAK------VVPQQITHTSPRIQPDYPAERSSLIPISGHRA 464 T P+ S+ T T N P++ V+P+ T T P L +G + Sbjct: 433 TSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPP-----------VLTSATGTQT 481 Query: 465 SPNPVAMETRS-DNRPSVPVQFQYFLPTYPPSA--YPLAAHTYTPITSSVSTIRQYPVSA 521 SP P + S D+ S L T PS + + + PI S+ S+ Q S Sbjct: 482 SPAPTTVTFGSTDSSTST-------LHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPST 534 Query: 522 QAPNSAITAQTGV-------GVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPA 574 + +++T+ + G ST + + +S I P+ S + Sbjct: 535 PSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFST 594 Query: 575 PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPI 634 I + P T+ + SA+ L + + T+A+ + ++ P Sbjct: 595 TIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPS 654 Query: 635 SNP------FSAAPAATT--VVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTL 686 + P + PA+ T V+ + +T+ P + P ++++ TL Sbjct: 655 TTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTL 714 Query: 687 IPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVS-METVSNQNNDQPT 745 P ESS+ + S G P + + S P + + + S P Sbjct: 715 TTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPG 774 Query: 746 IAVPPTAQQPPPTIPTMIAAASP---PSQPAVALSTIPGAVPITPPITTIAAAPPPSVTV 802 ++ P +P ++PT++ +S PS P S P A TP TT+ + +T Sbjct: 775 VSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTP--TTLTSRRTTRITS 832 Query: 803 GGSLSSVL 810 + S L Sbjct: 833 QMTTQSTL 840 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 73.2 bits (178), Expect = 1e-12 Identities = 136/619 (21%), Positives = 223/619 (36%), Gaps = 87/619 (14%) Query: 225 IGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNA 284 IG + +P A A S+ T+ P S+ P + + A PP ++ Sbjct: 65 IGGATIPESAPRAGPTRSAG-TSSRNPASRPPASGRGERA------------PPAKNTSP 111 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTR 344 P + S T P+ + + ++R + + P +A+S RD Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSA---GARRDT--- 164 Query: 345 ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAP 404 S P GTP + ++ G P A + P T + ++ S T P Sbjct: 165 ----SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220 Query: 405 TST----------IVTMTVPSHSSHATAVTTS--NIPVAKVVPQQITHTSPRIQPDYPAE 452 + + S SS AT +++ + P A+ P+ H S A Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280 Query: 453 RSSLIPISGHRASP--NPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSS 510 R + A+P P++ + PS +Q Q P P H+ + Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ------APPTLPATPHSSSLTCQL 334 Query: 511 VSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 + + P S AP S T + + + T+ A+H+ P+P + Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS-----FLPSPPLSPL 389 Query: 571 IQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ-PEGKTSAVVLADGATI 629 P P P + PL A+P +P+ T PQ P ++ A + Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASP------PLSPLATPSPQAPNALAVHLLQAPFSPP 443 Query: 630 VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP 689 + P+ PFS PA+ V + S + + AP ++P + PA+ M+ T P Sbjct: 444 PSPPVQAPFSP-PASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 690 QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET----VSNQNNDQPT 745 PP +A+P ++ AKP + ++ATP ++ + Q P+ Sbjct: 501 APPPLAAPPLQL-------------AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547 Query: 746 IAVPPTA-QQPPPTIPTMIAAAS---PPSQPAVALSTIPGAVPITPPIT-------TIAA 794 ++P + PPP P ++AA PPS PA P P P T T+A Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 607 Query: 795 APPPSVTVGGSLSSVLGPP 813 AP P S SS L P Sbjct: 608 APGPPPPPSRSPSSTLSGP 626 Score = 65.9 bits (159), Expect = 2e-10 Identities = 78/316 (24%), Positives = 124/316 (39%), Gaps = 36/316 (11%) Query: 562 QPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAV 621 QP P Q ++P + P AP G S++P+ T P+P Q Q A Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLAT----PSPSAALQSQAPPTLPAT 324 Query: 622 VLADGATI---VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATD 678 + T P++ P +AP + + + + + A SP + Sbjct: 325 PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384 Query: 679 GMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSN 738 ++ T P PP +A P +++ P P + P S + ATP + ++ Sbjct: 385 PLSPLATPPPQAPPALALPPLQAP-------PSPPASPPLSPL----ATPSPQAPNALAV 433 Query: 739 QNNDQPTIAVP-PTAQQP--PPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT---TI 792 P P P Q P PP P + +A+PPSQ +L+ P VP +PP + + Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493 Query: 793 AAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP-PLAT----NTVSPSL 847 +A PPP + PP+ K + P P+ A+P P A+ SPS Sbjct: 494 SATPPPQAP-----PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548 Query: 848 ALLANNLSMPTSDLPP 863 +L + L+ P PP Sbjct: 549 SLPMSPLATPPPQAPP 564 Score = 63.5 bits (153), Expect = 1e-09 Identities = 138/611 (22%), Positives = 211/611 (34%), Gaps = 83/611 (13%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 P + A P T S A P + A + + P P A RP Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP--GPVSSPGRASGTTRPGP 128 Query: 338 SRDVTTRITLPSHPALG----TPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSAT 393 RI+ A G PK+ + + S TP T +P +A + + T Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP---GTPSPAMARRSRAAGT 185 Query: 394 TAG----SVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 G + S P + +V S S H+T T P A+ P +P Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHST---TEPSPAARRRPSAGGGLQ---RPAS 239 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPL---AAHTYTP 506 + SS P+S S R+ PS P + PP P AA P Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGP 298 Query: 507 ITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM--QLMTVDASHARHIQGIQPA 564 ++SS P++ +P++A+ +Q + +T H + + QL T P Sbjct: 299 LSSS-------PLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT-------------PL 338 Query: 565 PISTQGIQPAPIGTPGIQ--PAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVV 622 P++ P+P P +Q P+P T + T + + LQ P Sbjct: 339 PLAP----PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP--------- 385 Query: 623 LADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAV 682 +P++ P AP A + + + +P PS A + +AV Sbjct: 386 --------LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS----PQAPNALAV 433 Query: 683 RKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNND 742 P PP SP V++ + P A P S+ S+A P + Sbjct: 434 HLLQAPFSPPP--SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491 Query: 743 QPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAP-PPSVT 801 P+ A PP PP P + A PP P AL+T P +PP + AP PS + Sbjct: 492 SPS-ATPPPQAPPPLAAPPLQLAKPPPQAPP-ALATPPLQALPSPPASFPGQAPFSPSAS 549 Query: 802 VGGSLSSVLGPPVPEIKVKE--EVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSM--- 856 + S + P P + +V P P + P T P ++ L++ Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALA 608 Query: 857 PTSDLPPGASP 867 P PP SP Sbjct: 609 PGPPPPPSRSP 619 Score = 57.8 bits (138), Expect = 6e-08 Identities = 136/586 (23%), Positives = 201/586 (34%), Gaps = 80/586 (13%) Query: 52 SGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV-----VVRPYPQVQM 106 S GL PA+ S AR S+ + ++ +P +RP PQV Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTP 287 Query: 107 LSTHHAVA----SATPVAVTAPPAHLT-------PAVPLSFSEGLMKPPPKPTMPSRPIA 155 A A S++P+A +P A L PA P S S P P P P A Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347 Query: 156 PAPPSTLSLPPKV-PGQVTVTMESSIPQA--SAIPVATISGQQGHPSNLHHIMTTNVQMS 212 P TL PP P Q T ++ S QA S +P +S P + + Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL-PPLQ 406 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAV-MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 S PPL A+ P+ A AV + + + P Q P + A P V Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466 Query: 272 PIQ-----SRPPVTTSNAIPPAVVATVSAT--------RAQSPVITTTAAHATDSALSRP 318 P Q + PP+ + P + + SAT A P+ AL+ P Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526 Query: 319 TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA 378 L P A+ Q P + +LP P P Q +A + +P A+ Sbjct: 527 PLQALPSPPASFPGQAP-----FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581 Query: 379 TV-APILATNTIPSATTAG-----------SVSHTQAPTSTIVTMTVPSHSSHATAVTTS 426 T+ AP P + +G +++P+ST+ + HSS AT+ T Sbjct: 582 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS-TPE 640 Query: 427 NIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQ 486 + P+ SP PD AE ++ P + R P+A P P+ Sbjct: 641 ELRGYDSGPEGGAAASP--PPD--AELAACHPAAWSRGPAPPLAFR----GAPGAPL--- 689 Query: 487 YFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV--------SAQAPNSAITAQTGVGVAS 538 +PP+ P +A I + P S A G G +S Sbjct: 690 ----PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 745 Query: 539 ----TVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPG 580 L + L + AS +H+ + +G G PG Sbjct: 746 RSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 791 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 73.2 bits (178), Expect = 1e-12 Identities = 164/726 (22%), Positives = 240/726 (33%), Gaps = 168/726 (23%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPK--VPGQV 172 S P+AV AP +P VP ++ P P P +P PP L PK P Sbjct: 321 SGQPLAV-APGLGSSPLVPAP--NVILHRTPTPIQP-KPAGVLPPKLYQLTPKPFAPAGA 376 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 T+T++ + A+P Q P NL + +++ S P P L Sbjct: 377 TLTIQG---EPGALPQ-----QPKAPQNLTFMAAGKAGQNVVLSGFPAPALQAN------ 422 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 + +PP TT+ A PP Sbjct: 423 ----------------------------------------VFKQPPATTTGAAPP----- 437 Query: 293 VSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSR-DVTTRITLPSHP 351 Q P ALS+P +S+ H + SI PAQ + LP P Sbjct: 438 ------QPP-----------GALSKP-MSV-HLLNQGSSIVIPAQHMLPGQNQFLLPGAP 478 Query: 352 ALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM 411 A+ P QQL + A T ++A + + AG +S ++ Sbjct: 479 AVQLP-QQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLS-----LGPVLAP 532 Query: 412 TVPSHSSHATAVTTSNI--PVAKVVPQQITHTS-PRIQPDYPAERSSLIPISGHRASPNP 468 +HS+H + + P +P + S P PA ++ + G P+ Sbjct: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSA 592 Query: 469 VAMETRSDN--RPSVPV----QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVS-- 520 VAM D +P+ P + L P P A T P+ +Q P + Sbjct: 593 VAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPT 652 Query: 521 --AQAPNSAITAQTGVGVASTVH---------LNPMQLMTVDASHARHIQGIQPAPISTQ 569 A AP A T Q G+AS+ P ++T D+ +Q P S Q Sbjct: 653 PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDS-----LQMFLPQERSQQ 707 Query: 570 GIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATI 629 PL +G H + P + + AP Q P P A +A GA + Sbjct: 708 ---------------PLSAEGPHLSVPASV--IVSAPPPAQDPAP-----ATPVAKGAGL 745 Query: 630 VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP 689 + S APA A+ G S PS+ + P D + P Sbjct: 746 GPQAPDSQASPAPAPQI-------PAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPH-PT 797 Query: 690 QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 749 +PP R +S R S P P+ A P + + NQ + VP Sbjct: 798 RPPSRPPSRPQSVSRPPSEPPLHPCPPPQ-------APPTLPGIFVIQNQ------LGVP 844 Query: 750 PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSV 809 P A P PT P P QP + + P P+ P ++ +V SS Sbjct: 845 PPASNPAPTAPG-------PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897 Query: 810 LGPPVP 815 L P P Sbjct: 898 LPAPTP 903 Score = 59.7 bits (143), Expect = 1e-08 Identities = 175/841 (20%), Positives = 294/841 (34%), Gaps = 141/841 (16%) Query: 104 VQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPK-PTMPSRPIAPAPPSTL 162 VQ + A A PV P PAV GL +P + P P A APP Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT 662 Query: 163 SLPPKVPGQVTVTMESSIPQA-SAIPVATIS------------GQQGHPSNLHHIMTTNV 209 + P PG + + + Q SA P A ++ QQ + H+ +V Sbjct: 663 TPQPS-PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL---SV 718 Query: 210 QMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA-------TAQ 262 S+I S P A+ + +GA S+ + P Q+P AA ++ Sbjct: 719 PASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA--PAPQIPAAAPLKGPGPSSS 776 Query: 263 PAVQH---IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPT 319 P++ H + P P T + PP+ +VS ++ P+ H + PT Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL------HPCPPPQAPPT 830 Query: 320 LSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT 379 L + + PA + P+ A G P+ L +Q P Sbjct: 831 LPGIFVIQNQLGVPPPASN---------PAPTAPGPPQPPLRPQSQP-------PEGPLP 874 Query: 380 VAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQIT 439 AP L ++ SA + S + ++ P T + S + + P +VP+ Sbjct: 875 PAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA 934 Query: 440 HTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPL 499 P P R+ + + A P P A+ R PS + Q P A P Sbjct: 935 -------PPPPPPRTFQMVTTPFPALPQPKALLERFHQVPS-GIILQNKAGGAP--AAPQ 984 Query: 500 AAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN--PMQLMTVDASHARH 557 + + P+TS +++ VS QAP+ TA + + + P L + + A + Sbjct: 985 TSTSLGPLTSPAASVL---VSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASN 1041 Query: 558 IQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGK 617 + + A ++ G PG P G Q GL+ P T QP E Sbjct: 1042 LPTLNVAKAASSG--------PG---KPSGLQ-----YESKLSGLKKPP--TLQPSKEAC 1083 Query: 618 TSAVVLADGATIVANPISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 + +++ F S A ++ H QG+ P PS K Sbjct: 1084 FLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVY--------QGALPSPSDYHKVDE 1135 Query: 677 ------------TDGMAVRKTLIPPQPPDVASPRVESSM--------RSTSGSPRPAGAK 716 T M + L+ + SP E M T+ + AK Sbjct: 1136 EFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAK 1195 Query: 717 PKSEIHVS----MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQP 772 K + +VS + P+ S E + + + P + QPPP +PT + + Sbjct: 1196 EKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGG 1255 Query: 773 AVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVP----------EIKVKEE 822 + +++ + ++ ++ +AA G + S PP+ ++K+K+E Sbjct: 1256 SPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQE 1315 Query: 823 VEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMP------------TSDLPPGASPRKK 870 ++ +A+ P+ P+ +A P T D PP A+P +K Sbjct: 1316 AGLSKVVHN-TALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERK 1374 Query: 871 P 871 P Sbjct: 1375 P 1375 >gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] Length = 3859 Score = 71.2 bits (173), Expect = 5e-12 Identities = 188/843 (22%), Positives = 290/843 (34%), Gaps = 116/843 (13%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 PV P V + V S T AV PA +P VP++ ++G + P P Sbjct: 589 PVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPAD-SPVVPVTPADGPVVPVASADSPF 647 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESS--IPQASA----IPVATISGQ------QGHPS 199 P+ PA +S+ P + VT S +P SA IPV T G+ G P Sbjct: 648 VPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPI 707 Query: 200 NLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA 259 + + ++ PG P+ G + S V P + Sbjct: 708 -----------VPVTPADTPGSPVTSA-----DGPVVPVTSADSPFVPVTPPDGPVVPVT 751 Query: 260 TAQPAVQHIIHQPIQSR--PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSR 317 +A V P+ S P V ++A P VA VS+ A PV+ T A A+ Sbjct: 752 SADGPV-----APVSSADGPVVPVTSADGP--VAPVSS--ADGPVVPVTPADTNGPAV-- 800 Query: 318 PTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPA---------LGTPKQQLHTMAQKTI 368 P S P I P +P PA +P + + Sbjct: 801 PVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVV 860 Query: 369 FSTGTPVAAATVAPI-------LATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHAT 421 + T V V P+ A T+ A S P +V P+ A Sbjct: 861 VDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVA- 919 Query: 422 AVTTSNIPVAKVVP-----QQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 VT+++ PV V P +T + P PA+ ++P++ + +PV T +D Sbjct: 920 PVTSADCPVVPVTPADSPADPVTAADGPVVPFTPAD-DPIVPVT---PADSPVVSVTPAD 975 Query: 477 NRPSVPVQF--QYFLPTYPPS----AYPLAAHTYTPITSSVSTIRQYPV-SAQAPNSAIT 529 P VPV F+P P + A P+T + S + PV SA P S +T Sbjct: 976 G-PVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPV--VPVTSADRPVSPVT 1032 Query: 530 AQTGVGVASTVHLNPMQLMT-VDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGT 588 G V T +P+ +T D + P T P TP P T Sbjct: 1033 TADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVT 1092 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVV 648 P+++ P+ +G + V ADG + P +PF A + Sbjct: 1093 SADGPVAPVSSADGPVVPV----TSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPI 1148 Query: 649 QTHSQSAS-------TNAPAQGSSPRPSILRKKPATDGMAVR-KTLIPPQPPDVASPRVE 700 + + S ++P +P S + P +G V + P P + + + Sbjct: 1149 VPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLV 1208 Query: 701 SSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ--PPPT 758 ST P P I V P VS D P I V P P + Sbjct: 1209 VLDSSTDVLVVP--VSPTDGILV----PDLADDPVVSVTIADSPVIPVTPADSPVVPVTS 1262 Query: 759 IPTMIAAASPPSQPAVALSTIPGAVPITP---PITTIAAAPPPSVTVGGSLSSVL----- 810 + + +P P + ++ + V +T P+ ++ A P + V + S V+ Sbjct: 1263 ADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTPA 1322 Query: 811 -GPPVPEIKVKEEVEPM----DIMRPVS-AVPPLATNTVSPSLALLANNLSMPTSDLPPG 864 GP VP P+ D + PV+ A P+ + T + S A+ P + Sbjct: 1323 DGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSA 1382 Query: 865 ASP 867 SP Sbjct: 1383 DSP 1385 Score = 69.3 bits (168), Expect = 2e-11 Identities = 173/798 (21%), Positives = 278/798 (34%), Gaps = 92/798 (11%) Query: 102 PQVQMLSTHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 P V + S TP V+ PA +PA+P++ ++ + P P P+ A Sbjct: 977 PVVPVASADSPFVPVTPADDPIVSVTPAE-SPAIPVTQADSPVVPVTSADRPVSPVTTAD 1035 Query: 159 ----PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGH----PSNLHHIMTTNVQ 210 P T + P VP T S + A V S P + + T+ Sbjct: 1036 GRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSAD 1095 Query: 211 MSIIR-SNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNA----ATAQPAV 265 + S+A GP + + ++ P ++A VT P + A PA Sbjct: 1096 GPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPAD 1155 Query: 266 QHIIHQPIQSRP--PVTTSNA----IPPAVVATVSATRAQSPVITTTAAHATDSALSRPT 319 ++ + P PVT +++ +PPA V + A SP + A L T Sbjct: 1156 SPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGL-VVLDSST 1214 Query: 320 LSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT 379 + P S I P + D +T+ P + + + S PV A Sbjct: 1215 DVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPAD 1274 Query: 380 VAPILATNTIP--SATTA-GSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQ 436 IL T P S TTA G V S ++ +T S S VT ++ PV V Sbjct: 1275 SPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVT--SADSPVVPVTPADGPVVPV--- 1329 Query: 437 QITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSA 496 T P PA+ ++P++ + +P+ T +++ P++PV P+ Sbjct: 1330 --TSADSPFVPVTPAD-DPIVPVT---PADSPIVSVTPAES-PAIPVT---------PAD 1373 Query: 497 YPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHAR 556 P+ P+TS+ S + P++ TG + P+ S Sbjct: 1374 SPVV-----PVTSADSPL--IPLTTAGSRVVPVTPTGDPIV------PVTPADTPGSPVT 1420 Query: 557 HIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEG 616 G P++ G P+ TP P T P+ T P+ P+G Sbjct: 1421 SADG-PVVPVTPAGDPIVPV-TPADTPGSPVTSADGPVVPVTTPDGPLVPVSP----PDG 1474 Query: 617 KTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 V ADG + P +PF A + + + S P P+ + P Sbjct: 1475 PVVPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPV-----TPADIPVVPV 1529 Query: 677 T--DGMAVRKTLIP-PQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSM 733 T +G + T P P + + + + ST P + P Sbjct: 1530 TPANGPVIHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTD------GVLVPDLADD 1583 Query: 734 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP---PIT 790 VS D P I V P P + A P P ++ IP VP+TP P+ Sbjct: 1584 PVVSVTIADSPVIPVTPADSTVVP-----VTLADGPVVPVTSVD-IP-VVPVTPANGPVA 1636 Query: 791 TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVS-AVPPLATNTVSPSLAL 849 + P V+V + SV+ + V ++ PV+ A P+ T + S + Sbjct: 1637 PVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVV 1696 Query: 850 LANNLSMPTSDLPPGASP 867 L + P + P SP Sbjct: 1697 LVTSADSPVIPVTPADSP 1714 Score = 67.4 bits (163), Expect = 7e-11 Identities = 155/735 (21%), Positives = 265/735 (36%), Gaps = 100/735 (13%) Query: 123 APPAHLTPA----VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTME- 177 +P +TPA VP++ ++G + P +P P+ PA + P V+V Sbjct: 1593 SPVIPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGPVAPVTPVDDPVVSVNPAD 1652 Query: 178 -SSIPQASA-IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAA 235 S +P SA PV ++ G + + + A P + + + P Sbjct: 1653 GSVVPVTSADCPVVPVTPADG--------------LVVPVTPADSPIVPVTPADSPVVLV 1698 Query: 236 AAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP----PVTTSNAIPPAVVA 291 +A VT P + +A T P P+ S PVT+++++P Sbjct: 1699 TSADSPVIPVTPADSPVVPVTSADTDSPG------SPVTSADGPVVPVTSADSLP----- 1747 Query: 292 TVSATRAQSPVITTTAAH---ATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLP 348 V T A PV+ T+A A S+ P + + S + + + D T +T Sbjct: 1748 -VPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPV---TTADDPTVPVTPA 1803 Query: 349 SHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNT----IPSATTAGSVSHTQAP 404 P + P + + S PV A +L ++T +P + T G + A Sbjct: 1804 DSPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLAD 1863 Query: 405 TSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQ-----ITHTSPRIQPDYPAERSSLIPI 459 +V++T+ S VT ++ PV V P +T + P PA+ + +IP+ Sbjct: 1864 -DPVVSVTIAD--SPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPAD-NPVIPV 1919 Query: 460 SGHRASPNPVAMETRSDNRPSVPV-QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYP 518 + +PV T +D+ P VPV + + P+ P+ TP S V + Sbjct: 1920 T---PVDDPVVPVTPADD-PIVPVTSADSPIVSVTPADSPV--FPVTPADSPVIPV---- 1969 Query: 519 VSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI----QGIQPAPISTQGIQPA 574 SA +P +T V V P+ +T S A + + P + + P Sbjct: 1970 ASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVIPV 2029 Query: 575 PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPI 634 +P + P + I TP + + P+ + V L D + P Sbjct: 2030 TADSPFVPVTPADSPVI-PVTPPDDLVVPVTPI-------DCPVVPVTLVDCPVVSVTPA 2081 Query: 635 SNPFS-AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPD 693 ++P PA VV ++P +P ++ D + V T P P Sbjct: 2082 NSPVDPVTPADGPVVPV----TPADSPVIPVTPADDLIVPVTPADSLIVSVT--PADSPV 2135 Query: 694 VASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQ 753 V +S + S + + P ++ V TP D P I V P Sbjct: 2136 VPVTPADSPVISVASADSPVVPVTPADTVVVPVTPA------------DGPVIPVTPAES 2183 Query: 754 QPPPTIP--TMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLG 811 P P + + +P P V ++ + PP + P+ T G ++S G Sbjct: 2184 PAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADG 2243 Query: 812 PPVPEIKVKEEVEPM 826 P VP + P+ Sbjct: 2244 PVVPVTSADSPLVPV 2258 Score = 65.1 bits (157), Expect = 3e-10 Identities = 189/884 (21%), Positives = 309/884 (34%), Gaps = 116/884 (13%) Query: 37 APSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 +P ++ A S + SA +P + V G V++ + + PV Sbjct: 1703 SPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSL--------------PV 1748 Query: 97 VVRPY--PQVQMLSTHHAVA---SATPVAVTAPPAHLTPAVPLSFSEGLMKP------PP 145 V P P V + S VA SA V PA +P VP++ ++ P P Sbjct: 1749 PVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPAD-SPVVPVTTADDPTVPVTPADSPV 1807 Query: 146 KPTMPSR-PIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 P P+ PI P + P +P V ++SS +PV+ G L Sbjct: 1808 VPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSST-DVLVVPVSPTDGI------LVPD 1860 Query: 205 MTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 + + +S+ +++P P+ A + V+ + V+ TS PA Sbjct: 1861 LADDPVVSVTIADSPVIPV--------TPADSPVVLVTPADGPVVPVTSVDNPVVPVTPA 1912 Query: 265 VQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQH 324 +I P V + A P V T A SP+++ T A + ++ P S Sbjct: 1913 DNPVIPVTPVDDPVVPVTPADDPIV----PVTSADSPIVSVTPADSPVFPVT-PADSPVI 1967 Query: 325 PPSAAISIQRPAQSRDVTTRITLPSH-PALGTPKQQLHTMAQKTIFSTGTPVAAAT--VA 381 P ++A S P D+ +P+ P + + + S PV +A V Sbjct: 1968 PVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVI 2027 Query: 382 PILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHT 441 P+ A + T A S P +V P VT + PV V P Sbjct: 2028 PVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCP-VVPVTLVDCPVVSVTPAN---- 2082 Query: 442 SPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAA 501 SP + P PA+ ++P++ + +PV T +D+ + + P+ P+ Sbjct: 2083 SP-VDPVTPAD-GPVVPVT---PADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVP 2137 Query: 502 HTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI--- 558 TP S V ++ SA +P +T V V T P+ +T S A + Sbjct: 2138 --VTPADSPVISV----ASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPA 2191 Query: 559 -QGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGK 617 + P + + P I P P + + TP +T G A +G Sbjct: 2192 DSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVA-------SADGP 2244 Query: 618 TSAVVLADGATIVANPISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 V AD + P +P PA + V S P + PA Sbjct: 2245 VVPVTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDP---VFPVTPA 2301 Query: 677 TDGM----AVRKTLIPPQP---PDVASPRVESSMR--STSGSPRPAGAKPKSEIHVSMAT 727 D + ++P P P V P S+ +++GSP + + +T Sbjct: 2302 DDPIFPVSPADSPVVPVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSST 2361 Query: 728 PVTVSMET---------------VSNQNNDQPTIAVPPTAQQPPPTIPT--MIAAASPPS 770 V V + + VS +D P I V PT P P + + Sbjct: 2362 DVLVVLVSPTDGIPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVD 2421 Query: 771 QPAVALSTIPG-AVPITPPITTIAAAPP---PSVTV---GGSLSSVLGPPVPEIKVKEEV 823 P V ++ +P+TP + + A P P V+V G + V +P I V Sbjct: 2422 SPVVPVTPADSPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSAD 2481 Query: 824 EPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 867 P+ + P + + T + S+ + A P + P SP Sbjct: 2482 SPVVPVTPADGL--VVPVTSADSVVVPATPADCPLVPVDPADSP 2523 Score = 60.5 bits (145), Expect = 9e-09 Identities = 179/862 (20%), Positives = 292/862 (33%), Gaps = 140/862 (16%) Query: 112 AVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQ 171 A+ + PV P +P VP++ ++G + P P+ PA +S+ P Sbjct: 360 AIPADGPVVPVTPAD--SPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPV 417 Query: 172 VTVTMESSIPQASAIPVATISGQ------QGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 V VT S IPV T G+ G P + + + S + S A GP + + Sbjct: 418 VPVTSADS----PLIPVTTADGRVVPVTAAGDP--IVPVTPADTPGSPVTS-ADGPVVPV 470 Query: 226 GASHLP-----------------RGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHI 268 ++ +P G A + V V S TA + + Sbjct: 471 TSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPV 530 Query: 269 --IHQPIQSRPPVTTSNAIP--PAVVATVSATRAQSPVITTTAAHA-------------- 310 P+ S P S AIP PA V T A PV+ T+A + Sbjct: 531 TPADSPVLSVTP-AESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVP 589 Query: 311 ---TDSAL------SRPTLSIQHPPSAAISIQRPAQSRDV-TTRITLPSHPALGTPKQQL 360 DS + P LS+ S A+ + PA S V T P P + Sbjct: 590 VTPADSPVVPVTPADSPVLSVTLADSPAVPV-TPADSPVVPVTPADGPVVPVASADSPFV 648 Query: 361 HTMAQKTIFSTGTPV---------AAATVAPILATN--TIPSATTAGSVSHTQAPTSTIV 409 + TP A + V P+ + + IP T G + A IV Sbjct: 649 PVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIV 708 Query: 410 TMT--------VPSHSSHATAVTTSNIPVAKVVPQQ-----ITHTSPRIQPDYPAE---- 452 +T V S VT+++ P V P +T + P A+ Sbjct: 709 PVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVV 768 Query: 453 --RSSLIPISGHRASPNPVAMETRSD-NRPSVPVQF--QYFLPTYPPSAYPL----AAHT 503 S+ P++ ++ PV T +D N P+VPV F+P P + + A Sbjct: 769 PVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSADSPFVPVIPADSPVVPVTPADDP 828 Query: 504 YTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVAST------VHLNPMQLMTVDASHARH 557 P+T + S+ +SA +P + G V + V + P+ + V A Sbjct: 829 IVPVTPADSSFVPV-ISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADET 887 Query: 558 IQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGK 617 + + PA + P + P + SA P+ P + Sbjct: 888 VVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSA---------DCPVVPVTP-ADSP 937 Query: 618 TSAVVLADGATIVANPISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 V ADG + P +P PA + VV A SP + PA Sbjct: 938 ADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGPVVPVASADSP---FVPVTPA 994 Query: 677 TDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETV 736 D + ++ P + P + + +S + + + RP ++ + T + V Sbjct: 995 DDPIV---SVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPV 1051 Query: 737 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP------PIT 790 + + + P + + +PP P V +++ G P+ P P+ Sbjct: 1052 TPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADG--PVAPVSSADGPVV 1109 Query: 791 TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPM----DIMRPVS-AVPPLATNTVSP 845 + +A P V SS GP VP P+ D + PV+ A P+ + T++ Sbjct: 1110 PVTSADGPVAPV----SSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLAD 1165 Query: 846 SLALLANNLSMPTSDLPPGASP 867 S + P +PP P Sbjct: 1166 SPVVPVTPADSPVIPVPPANGP 1187 Score = 56.2 bits (134), Expect = 2e-07 Identities = 169/761 (22%), Positives = 264/761 (34%), Gaps = 107/761 (14%) Query: 113 VASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQV 172 V SA V PA P VP++ + G + P P P+A A + + P Sbjct: 111 VTSADDPVVPITPAD-NPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVF 169 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 VT P S + T + P +T +I + A GP +H+ ++ Sbjct: 170 PVT-----PADSPLFPVTPADSPLFP------VTPADSAAIPVTPADGPVVHVTPAN--- 215 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 G + S V TV S + PA I+ PVT +++ + V Sbjct: 216 GTVVPVTPADSPVVTVASTDSPV---VPVTPADDPIV--------PVTPADS---SFVPV 261 Query: 293 VSATRAQSPVITTTAAHATDSALS------RPTLSIQHPPSAAISIQRPAQSRDVTTRIT 346 +SA PVI DS+ P I P A +I + +T Sbjct: 262 ISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVT 321 Query: 347 LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNT--IPSATTAGSVSHTQAP 404 P + T A + S +A + V P+ ++ +P+ G V Sbjct: 322 TADDPIVPV------TPADSPVLS--VTLADSPVVPVTPADSPFVPAIPADGPVVPVTPA 373 Query: 405 TSTIVTMT--------VPSHSSHATAVTTSNIPVAKVVPQQ-----ITHTSPRIQPDYPA 451 S +V +T V S S VT ++ P+ V P +T + P A Sbjct: 374 DSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTA 433 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 + ++P++ A+ +P+ T +D P PV P P ++ + TP V Sbjct: 434 D-GRVVPVT---AAGDPIVPVTPADT-PGSPVT-SADGPVVPVTSADIPLVPVTPPDGPV 487 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNP-MQLMTVDASHARHIQGIQPAPISTQG 570 + SA P + +++ G V T +P + + T D I + PA Sbjct: 488 VPV----TSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDL----IVPVTPADSPVLS 539 Query: 571 IQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIV 630 + PA +P I P + I TP N P T P V+ ADG + Sbjct: 540 VTPAE--SPAIPVTPADSP-IVPVTPAN----GPVVPVTSADSP---FVPVIPADGPVVP 589 Query: 631 ANPISNP-FSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAV-----RK 684 P +P PA + V+ ++PA +P S + DG V Sbjct: 590 VTPADSPVVPVTPADSPVLSV----TLADSPAVPVTPADSPVVPVTPADGPVVPVASADS 645 Query: 685 TLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQP 744 +P P D P V + + P P + V+ A + + T + Sbjct: 646 PFVPVTPAD--DPIVSVTPAESPAIPVTQADSP--VVPVTSADRPVIPVTTADGRIVPVT 701 Query: 745 TIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP---PITTIAAAPPPSVT 801 P P T + + +A P P + + VP+TP P+ + +A P Sbjct: 702 AAGDPIVPVTPADTPGSPVTSADGPVVPVTSADS--PFVPVTPPDGPVVPVTSADGPVAP 759 Query: 802 VGGSLSSVLGPPVPEIKVKEEVEPMDIM-RPVSAVPPLATN 841 V SS GP VP V P+ PV V P TN Sbjct: 760 V----SSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTN 796 Score = 54.3 bits (129), Expect = 6e-07 Identities = 178/813 (21%), Positives = 283/813 (34%), Gaps = 161/813 (19%) Query: 95 PVVVRPYPQVQMLSTHHAVASATP---VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 P +R +P V ST V ++TP + V PA VP++ G + P P Sbjct: 2868 PDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCAD-VPVNPVNGPVVPDLSGDCPV 2926 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQAS-------AIPVATISGQQGHP--SNLH 202 P+ P + PP V V T + P + +PV +G S Sbjct: 2927 VPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVAPVTLSEYP 2986 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 + T +++ GP + P +A ++V+S+ ++ +PN A Sbjct: 2987 DVTVTPADGTVVSPTIGGPVV-------PDPSADSSVVSNPTTDGLI-----VPNPLLAG 3034 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVAT---VSATRAQSPVIT--TTAAH------AT 311 P V P T + P ++A V+ T A PV+ TT A Sbjct: 3035 PVV-----------PVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPDPTAE 3083 Query: 312 DSALSRPTLS---IQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTM----- 363 +S PT+ + +P + + PA DV P PA P ++ + Sbjct: 3084 GLVVSNPTVDDPVVTNPSTKGLVSATPADCADV------PVIPA-DCPDVLVNLVNDSVV 3136 Query: 364 ----AQKTIFSTGTP----------VAAATVAPILATNTIPSATTAG---SVSHTQAPTS 406 A T+ S P + PI +P TT G SV+ AP Sbjct: 3137 PDFTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVV 3196 Query: 407 TI-------VTMT------VPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAER 453 + VT+T VP SS V S + +VP +T + PD PA Sbjct: 3197 PVFLTDCPDVTVTPADSPVVPDPSSDGPVVADS-LDDDGLVP--VTPADDSVVPDSPAN- 3252 Query: 454 SSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVST 513 ++P + PVA + D P VPV P+ P + T Sbjct: 3253 GLVVP---DPTTDGPVAPDPSVDG-PVVPVT---------PADAPTVSVTL--------- 3290 Query: 514 IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQP 573 A P+ +T G+ V+ + P+ S + PA S + P Sbjct: 3291 -------ADCPDVTVTPPDGLVVSDSKRGGPV---VTGLSTNDPVITATPADFSDVTVTP 3340 Query: 574 APIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLA--DGATIVA 631 A + PA ++ +P+ + + P + VVL D +V Sbjct: 3341 ADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDD----LVVLEPPDKVPVVP 3396 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQP 691 +PISN + T + +A+T+ GS ++ PA DG TL Sbjct: 3397 DPISNGLVVSDPIT------NNTAATDPSVDGS-----VVPVSPA-DGPVAPVTLA--DC 3442 Query: 692 PDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPT 751 PDV + S+ S S P + S VS+ D P + +PP Sbjct: 3443 PDVTITPADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPP- 3501 Query: 752 AQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLG 811 P + A PP + V I ++ ++ P+T A PS + G + V+ Sbjct: 3502 --------PDDLVAPEPPDEVPVVPDPITDSLVVSDPMTDGPVASDPS--IDGIVVPVVS 3551 Query: 812 PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVS 844 P + V + V + I+ SA P+ T++ Sbjct: 3552 P--SGLLVLDSVADVSILPDTSADVPVTPVTLA 3582 Score = 47.0 bits (110), Expect = 1e-04 Identities = 171/744 (22%), Positives = 255/744 (34%), Gaps = 139/744 (18%) Query: 112 AVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQ 171 +VASA V PA T VP++ ++G + P P+ P+ PA + + P Sbjct: 2147 SVASADSPVVPVTPAD-TVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPV 2205 Query: 172 VTVTMESS----IPQAS--AIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 V VT S +P AS +PV T + G P ++A GP + + Sbjct: 2206 VPVTPADSPIVPVPPASDPVVPV-TPADTPGSPV----------------ASADGPVVPV 2248 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSN-- 283 ++ P S V V S + +A V PVT ++ Sbjct: 2249 TSADSP---LVPVTPGDSPVVPVTPADSPVFPVTSADGPVF-----------PVTLADDP 2294 Query: 284 --AIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDV 341 + PA + A SPV+ T A+ P + + PP+ + + Sbjct: 2295 VFPVTPADDPIFPVSPADSPVVPVTPANI-------PVVPV--PPANGSVVPVTSAGSPF 2345 Query: 342 TTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401 I L + L + T G PV P LA + + S TT+ S Sbjct: 2346 VPIIPADGLVVLDSSTDVLVVLVSPT---DGIPV------PDLADDPVVSVTTSDSPVIP 2396 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 PT + V P+ VT+ + PV V P SP I P PA+ S ++P + Sbjct: 2397 VTPTDSPVVPVAPADGP-VVPVTSVDSPVVPVTPAD----SPVI-PVTPAD-SLVVPAT- 2448 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSA-YPLAAHT-----YTPITSSVSTIR 515 + +PV T +D P VPV SA P+ T P+TS+ S + Sbjct: 2449 --PADDPVVSVTPADG-PVVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSADSVVV 2505 Query: 516 QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAP 575 A P + V T + NP+ +T D S + + PA S + PA Sbjct: 2506 P-ATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSP---VFPVTPADSSVVPVTPA- 2560 Query: 576 IGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPIS 635 G+ P+ T G P+ P V AD P Sbjct: 2561 ----GVPVVPV-TPGDGPVVPVTPADSLVVP--------------VTSADSPVFPVTPAD 2601 Query: 636 NP-FSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDV 694 +P F +PA VV ++P SP S + DG V T P P V Sbjct: 2602 SPVFPVSPADDLVVPV----TPGDSPVVPVSPADSPVVLVTPADGPVVPVT--PANGPVV 2655 Query: 695 ASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 754 +S + +++ V P I VP A Sbjct: 2656 PVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPTD--------------GILVPDLADD 2701 Query: 755 PPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV 814 P + +P P V ++ PG P+ P +T P VT +GP V Sbjct: 2702 P-------VVPVTPGDDPVVPVT--PGDDPVIP-VTPADDGPFVPVT------PAVGPVV 2745 Query: 815 PEIKVKEEVEPMDIM-RPVSAVPP 837 P++ + V P + PV +V P Sbjct: 2746 PDLTADDSVVPDSLTDDPVISVCP 2769 Score = 40.0 bits (92), Expect = 0.012 Identities = 175/826 (21%), Positives = 280/826 (33%), Gaps = 146/826 (17%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPP 159 P P + S +PV P +P VP++ ++G + P T P+ P P Sbjct: 2375 PVPDLADDPVVSVTTSDSPVIPVTPTD--SPVVPVAPADGPVVP---VTSVDSPVVPVTP 2429 Query: 160 STLSLPPKVPGQVTVTMESSIPQASA-IPVATISGQQGHPSNLHHIMTTNVQ-MSIIRSN 217 + + P P V +P A PV +++ G + + T ++ +S+ ++ Sbjct: 2430 ADSPVIPVTPADSLV-----VPATPADDPVVSVTPADG---PVVPVTTADIPVISVTSAD 2481 Query: 218 APGPPL-HIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA-QPAVQHIIHQPIQS 275 +P P+ +P +A + V+ ++ L P + P ++ Sbjct: 2482 SPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDD 2541 Query: 276 RP--PVTTSNA----IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA 329 P PVT +++ + PA V V T PV+ T A +L P S P Sbjct: 2542 SPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPA----DSLVVPVTSADSPVFPV 2597 Query: 330 ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI 389 P + +P P +P + + T V P A + Sbjct: 2598 TPADSPVFPVSPADDLVVPVTPG-DSPVVPVSPADSPVVLVTPADGPVVPVTP--ANGPV 2654 Query: 390 PSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 T+A S P +V + + T I V + + +P P Sbjct: 2655 VPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDP-- 2712 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH------- 502 ++P++ +PV T +D+ P VPV P P L A Sbjct: 2713 ------VVPVT---PGDDPVIPVTPADDGPFVPV-----TPAVGPVVPDLTADDSVVPDS 2758 Query: 503 -TYTPITSSV--------STIRQ--------YPVSAQAPNSAITAQTGVGVAST---VHL 542 T P+ S T+R YPV+ + V V T V L Sbjct: 2759 LTDDPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAADCPVVSVPLTDGLVVL 2818 Query: 543 NPMQLMTVDASHARHIQG-IQPAPISTQGIQPAP-IGTPGIQPAPLGTQGIHS---ATPI 597 P V A H G + P P+ + P + P + A G+ A P+ Sbjct: 2819 CPPD--EVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVASADNPGVPDPIRAFPV 2876 Query: 598 NTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAST 657 + +P+ T P + V AD A + NP++ P VV S Sbjct: 2877 VPKPSTFSPVVTSTP-ADWIDVIVTPADCADVPVNPVNGP---------VVPDLS----- 2921 Query: 658 NAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKP 717 G P + P TD + V PPDV V ST + P P Sbjct: 2922 -----GDCPVVPV----PPTDDIVVL------NPPDVVFAVV-----STPVTDGPVVTDP 2961 Query: 718 KSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP---TAQQPP---PTIPTMIAAASPPSQ 771 ++ + TP S+ V+ ++ P + V P T P P +P A +S S Sbjct: 2962 ATDGLMVPVTPANGSVAPVT--LSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSN 3019 Query: 772 PAVALSTIPG------AVPITP---PITTIAAAPPPSVTVGGSLSSVL------GPPVPE 816 P +P VP+TP P+ + A P VTV + V+ GP P+ Sbjct: 3020 PTTDGLIVPNPLLAGPVVPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPD 3079 Query: 817 IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 862 E + + P + P+ TN PS L + +D+P Sbjct: 3080 ----PTAEGLVVSNP-TVDDPVVTN---PSTKGLVSATPADCADVP 3117 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 70.9 bits (172), Expect = 6e-12 Identities = 164/711 (23%), Positives = 246/711 (34%), Gaps = 124/711 (17%) Query: 133 PLSFSEGLMKP-PPKPTMPSRPIAPAPPSTLS---------LPPKVPGQVTVTMESSIPQ 182 P + + GL+ P PP P P+ PA L L + G T+ S P+ Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 183 A----SAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP----PLHIGASH-LPRG 233 A ++ P A+ G++ P+ + + PGP L I A + RG Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136 Query: 234 AAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 A A S+ R TS P T PA+ +SR T PA A Sbjct: 137 KATEAPKRSALSAGARRDTSG-PTPGTPSPAMAR------RSRAAGTEVGLPRPAPSARP 189 Query: 294 SA-TRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP- 351 T +++ + H+T + P+ + + PSA +QRPA SR +++ T S P Sbjct: 190 RPPTEGPRKSVSSASEHST----TEPSPAARRRPSAGGGLQRPA-SRSLSSSATPLSSPA 244 Query: 352 -----ALGTPKQQLHTMAQKTIFSTG------TPVAAATVAPILATNTIPSATTAGSVSH 400 A GTP+ H K TP + ++ P AT + S Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304 Query: 401 TQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHT---SPRIQP--DYPAERSS 455 + + ++ T+ P + + A T+ P Q TH+ SP + P P + Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTL-----QATHSFLPSPPLSPLATPPPQAPP 359 Query: 456 LIPISGHRASPNPVA------METRSDNRPSV----PVQFQYFLPTYPPSAYPLAAHTYT 505 + + +A P+P A + T S P+ +Q + P PP P + Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419 Query: 506 PITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAP 565 P++ S + Q P S AP P+Q + P+P Sbjct: 420 PVSPSATPPSQAPPSLAAP-------------------PLQ--------------VPPSP 446 Query: 566 ISTQGIQPAPIGTPGIQPAPLGTQGIHSA--TPINTQGLQPAPMGTQQPQPEGKTSAVVL 623 ++ + P+ P P PL + A P L P+ P Sbjct: 447 PASPPMSPSATPPPQ-APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505 Query: 624 ADGATIVANPISNPFSAAP---AATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGM 680 + A++ +P++ P AP AA + S AS A P P P T Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----PDTSVS 560 Query: 681 AVRKTL-IPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQ 739 R TL + P PP P S ST P AG H S AT + + Sbjct: 561 GPRLTLALAPGPP----PPPSRSPSSTLSGPDLAG-------HSSSATSTPEELRGYDSG 609 Query: 740 NNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT 790 + PP A+ AA S P +A PGA PP T Sbjct: 610 PEGGAAASPPPDAE----LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656 Score = 67.8 bits (164), Expect = 5e-11 Identities = 142/617 (23%), Positives = 218/617 (35%), Gaps = 69/617 (11%) Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI 285 GA+ A A +++ + P P A A + +P+ R I Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 286 PPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRI 345 P + TR P + A + + P P A RP RI Sbjct: 71 PESA-PRAGPTRTSRPPASGRGERAPPAKNTSP--GPVSSPGRASGTTRPGPLGQKGLRI 127 Query: 346 TLPSHPALG----TPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAG----S 397 + A G PK+ + + S TP T +P +A + + T G + Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSGPTP---GTPSPAMARRSRAAGTEVGLPRPA 184 Query: 398 VSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLI 457 S P + +V S S H+T T P A+ P +P + SS Sbjct: 185 PSARPRPPTEGPRKSVSSASEHST---TEPSPAARRRPSAGGGLQ---RPASRSLSSSAT 238 Query: 458 PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPL---AAHTYTPITSS--VS 512 P+S S R+ PS P + PP P AA P++SS + Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQ 572 P S AP S T + + + T+ A+H+ P+P + Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS-----FLPSPPLSPLAT 352 Query: 573 PAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ-PEGKTSAVVLADGATIVA 631 P P P + PL A+P +P+ T PQ P ++ A + + Sbjct: 353 PPPQAPPALALPPLQAPPSPPASP------PLSPLATPSPQAPNALAVHLLQAPFSPPPS 406 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQP 691 P+ PFS PA+ V + S + + AP ++P + PA+ M+ T P P Sbjct: 407 PPVQAPFSP-PASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463 Query: 692 PDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET----VSNQNNDQPTIA 747 P +A+P ++ AKP + ++ATP ++ + Q P+ + Sbjct: 464 PPLAAPPLQL-------------AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510 Query: 748 VPPTA-QQPPPTIPTMIAAAS---PPSQPAVALSTIPGAVPITPPIT-------TIAAAP 796 +P + PPP P ++AA PPS PA P P P T T+A AP Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570 Query: 797 PPSVTVGGSLSSVLGPP 813 P S SS L P Sbjct: 571 GPPPPPSRSPSSTLSGP 587 Score = 60.1 bits (144), Expect = 1e-08 Identities = 90/386 (23%), Positives = 144/386 (37%), Gaps = 51/386 (13%) Query: 489 LPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLM 548 LP PSA P T P SVS+ ++ + +P + G G+ + Sbjct: 180 LPRPAPSARPRPP-TEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237 Query: 549 TVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMG 608 T +S AR + S +G AP QP P G Q + P Sbjct: 238 TPLSSPAR-------SGPSARGTPRAPAHPS--QPKPKGLQALR-------------PPQ 275 Query: 609 TQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRP 668 P+ + + L+ +P + P +AP + + + + + A SP Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335 Query: 669 SILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATP 728 + ++ T P PP +A P +++ P P + P S + ATP Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAP-------PSPPASPPLSPL----ATP 384 Query: 729 VTVSMETVSNQNNDQPTIAVP-PTAQQP--PPTIPTMIAAASPPSQPAVALSTIPGAVPI 785 + ++ P P P Q P PP P + +A+PPSQ +L+ P VP Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444 Query: 786 TPPIT---TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP-PLAT- 840 +PP + + +A PPP + PP+ K + P P+ A+P P A+ Sbjct: 445 SPPASPPMSPSATPPPQAP-----PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499 Query: 841 ---NTVSPSLALLANNLSMPTSDLPP 863 SPS +L + L+ P PP Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPP 525 Score = 56.2 bits (134), Expect = 2e-07 Identities = 144/634 (22%), Positives = 216/634 (34%), Gaps = 87/634 (13%) Query: 251 PTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHA 310 P ++ P T +P P RPP PP A + A V A Sbjct: 17 PAARAPGLLTPRP--------PGSPRPP-------PPVTPAALRVLGAAGAVGRKPLAER 61 Query: 311 TDSALSRPTLSIQHPPSAAISIQRPAQS----RDVTTRITLPSHPALGTPKQQLHTMAQK 366 + T+ P + RP S R + T P + +P + T Sbjct: 62 A-GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPG--PVSSPGRASGTTRPG 118 Query: 367 TIFSTGTPVAAA-TVAPILATNTIP-SATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVT 424 + G ++A TVA AT SA +AG+ T PT P S A A Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--------PGTPSPAMARR 170 Query: 425 TSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRAS-PNPVAMETRSDNRPSVPV 483 + +P+ PR P R S+ S H + P+P A RPS Sbjct: 171 SRAAGTEVGLPRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARR-----RPSAGG 223 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 Q P++ L++ TP++S R P SA+ A + L Sbjct: 224 GLQR------PASRSLSSSA-TPLSSPA---RSGP-SARGTPRAPAHPSQPKPKGLQALR 272 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQG--IQPAPIGTPGIQ--PAPLGTQGIHSATPINT 599 P Q+ A + + +P++T P+P P +Q P+P T + T + + Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332 Query: 600 QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNA 659 LQ P +P++ P AP A + + + + Sbjct: 333 PTLQATHSFLPSPP-----------------LSPLATPPPQAPPALALPPLQAPPSPPAS 375 Query: 660 PAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKS 719 P PS A + +AV P PP SP V++ + P A P S Sbjct: 376 PPLSPLATPS----PQAPNALAVHLLQAPFSPPP--SPPVQAPFSPPASPPVSPSATPPS 429 Query: 720 EIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI 779 + S+A P + P+ A PP PP P + A PP P AL+T Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKPPPQAPP-ALATP 487 Query: 780 PGAVPITPPITTIAAAP-PPSVTVGGSLSSVLGPPVPEIKVKE--EVEPMDIMRPVSAVP 836 P +PP + AP PS ++ S + P P + +V P P + Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-TLQA 546 Query: 837 PLATNTVSPSLALLANNLSM---PTSDLPPGASP 867 P T P ++ L++ P PP SP Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580 Score = 55.1 bits (131), Expect = 4e-07 Identities = 130/567 (22%), Positives = 197/567 (34%), Gaps = 71/567 (12%) Query: 59 NPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTH---HAVAS 115 +PAA +G + A +SSS++ S + P R P+ + + + Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQA 270 Query: 116 ATPVAVTAPPAHLTPAV-PLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKV-PGQVT 173 P VT P PA+ PLS S P P+ P P AP TL PP P Q T Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSP---LATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327 Query: 174 VTMESSIPQA--SAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLP 231 ++ S QA S +P +S P + + S PPL A+ P Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL-PPLQAPPSPPASPPLSPLATPSP 386 Query: 232 RGAAAAAV-MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ-----SRPPVTTSNAI 285 + A AV + + + P Q P + A P V P Q + PP+ + Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446 Query: 286 PPAVVATVSAT--------RAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 P + + SAT A P+ AL+ P L P A+ Q P Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-- 504 Query: 338 SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATV-APILATNTIPSATTAG 396 + +LP P P Q +A + +P A+ T+ AP P + +G Sbjct: 505 ---FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561 Query: 397 -----------SVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRI 445 +++P+ST+ + HSS AT+ T + P+ SP Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS-TPEELRGYDSGPEGGAAASP-- 618 Query: 446 QPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT 505 PD AE ++ P + R P+A P P+ +PP+ P +A Sbjct: 619 PPD--AELAACHPAAWSRGPAPPLAFR----GAPGAPL-------PWPPATGPGSADGLC 665 Query: 506 PITSSVSTIRQYPV--------SAQAPNSAITAQTGVGVAS----TVHLNPMQLMTVDAS 553 I + P S A G G +S L + L + AS Sbjct: 666 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQAS 725 Query: 554 HARHIQGIQPAPISTQGIQPAPIGTPG 580 +H+ + +G G PG Sbjct: 726 VVQHLLSRTLLLAAAEGAAGGSGGGPG 752 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 69.7 bits (169), Expect = 1e-11 Identities = 194/936 (20%), Positives = 333/936 (35%), Gaps = 137/936 (14%) Query: 35 LGAPSTGLSQAPSQIA------NSGSAGLINPAATVNDESGRD----SEVSAREHMSSSS 84 LG ST P N+ ++GL+ + V+ +G S + S+ Sbjct: 3328 LGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST 3387 Query: 85 SLQSREEKQEPVVVRPYPQ---VQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLM 141 + QS ++ P V++ +T H S+TP H + + S L Sbjct: 3388 TFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT------HFSAS-----STTLG 3436 Query: 142 KPPPKPTMPSRPIAPAP---PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHP 198 + T+ S P+A A P+ + V T Q P + + +G Sbjct: 3437 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496 Query: 199 SNLHHIMTTNVQMSIIRSNAP---------GPPLHIGASHLP-------RGAAAAAVMSS 242 S H TT+ S + + P +H P R + A SS Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 3556 Query: 243 SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVV-------ATVSA 295 T T LP +T + PI S TT A+P + +T Sbjct: 3557 QDATG----TIVLPARSTTSVLLGESTTSPISSGSMETT--ALPGSTTTPGLSEKSTTFH 3610 Query: 296 TRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAI------SIQRPAQSRDVTTRITLPS 349 + +SP T + A T S +S + + P + S P SR TT S Sbjct: 3611 SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT-----S 3665 Query: 350 HPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTA-----GSVSHTQAP 404 H + G+ L + T S+ + + + T P +TTA S + +P Sbjct: 3666 HSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSP 3725 Query: 405 TSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI----THTSPRIQPDYPAERSSLIPIS 460 ST T+ S +S ++ + + P+ + TSP +Q + A ++ P S Sbjct: 3726 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH--PAS 3783 Query: 461 GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYP-V 519 H +P+P + T P + P P+ + A+ T + + + P Sbjct: 3784 TH-TTPSPPSTATA----PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 3838 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 S P+SA + +G G ++T ++P I+T P TP Sbjct: 3839 SGTTPSSAHSTTSGRGESTTSRISPGS-----------------TEITTL---PGSTTTP 3878 Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFS 639 G+ A + +S+ T L PA M TS V + T + P S + Sbjct: 3879 GLSEA---STTFYSSPRSPTTTLSPASM----------TSLGVGEESTTSRSQPGSTHST 3925 Query: 640 AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRV 699 +PA+TT +S + + + GS+ ++ + T T +P + + Sbjct: 3926 VSPASTTTPGLSEESTTVYSSSPGST-ETTVFPRSTTTSVRREEPTTFHSRPASTHT-TL 3983 Query: 700 ESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA-VPPTAQQPPPT 758 + +TSG + A P S P T++ + ++ P+ + T P + Sbjct: 3984 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS 4043 Query: 759 IPTMIAAASPPSQ---PAVALSTIPGAVPITPPI----TTIAAAP-PPSVTVGGSLSSVL 810 + + S PS+ + +T+PG+ P TP + TT +P P T+ + ++ Sbjct: 4044 TTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 4102 Query: 811 GPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT-VSPSLALLANNLSMPTSDLPPGASPRK 869 G V E +P +A P T + +S ++ + L PG++ Sbjct: 4103 G--VSEESSTSHSQPGS--THTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTAS 4158 Query: 870 KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKA 905 +Q + GD T DD T S LV+A Sbjct: 4159 SLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEA 4191 Score = 65.5 bits (158), Expect = 3e-10 Identities = 168/768 (21%), Positives = 284/768 (36%), Gaps = 102/768 (13%) Query: 170 GQVTVTMESSIPQASAIPVATISGQQGHPSNLHH----IMTTNVQMSIIRSNAPGPPLHI 225 G+ + T SS + +T S P++ H TT+ S S G Sbjct: 854 GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS---STTSGRSEES 910 Query: 226 GASHLPRGAAAAAVMSSSKVTTVL---RPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTS 282 ASH + A V+ + T+VL TS + + + A+ P S TT Sbjct: 911 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERS-TTF 969 Query: 283 NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVT 342 ++ P + T+S P TT++ + +S SR H + S P SR T Sbjct: 970 HSSPRSPATTLS------PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHST 1023 Query: 343 TRIT---------LPSHPALGTPKQQLHTMAQKTIFSTGTPVA-AATVAPILATNTIPSA 392 T + LP+ P Q+ T + + ST T ++ +T A + Sbjct: 1024 TSHSSPGSTDTTLLPASTTTSGPSQE-STTSHSSSGSTDTALSPGSTTALSFGQESTTFH 1082 Query: 393 TTAGSVSHTQAPTST----IVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPD 448 + GS T P ST IV + HSS + TT + + TSP +Q + Sbjct: 1083 SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS---------PASSTSPGLQGE 1133 Query: 449 YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT 508 A ++ P S H +P+P + T P + P P+ + A+ T + + Sbjct: 1134 STAFQTH--PASTH-TTPSPPSTATA----PVEESTTYHRSPGSTPTTHFPASSTTSGHS 1186 Query: 509 SSVSTIRQYP-VSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIS 567 + P S P+SA + +G G ++T ++P I+ Sbjct: 1187 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS-----------------TEIT 1229 Query: 568 TQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGA 627 T P TPG+ A + +S+ T L PA M TS V + Sbjct: 1230 TL---PGSTTTPGLSEA---STTFYSSPRSPTTTLSPASM----------TSLGVGEEST 1273 Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLI 687 T + P S + +PA+TT +S + + ++GS+ ++ T T Sbjct: 1274 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGST-ETTVFPHSTTTSVHGEEPTTF 1332 Query: 688 PPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA 747 +P + + + +TSG + A P S P T++ + ++ P+ + Sbjct: 1333 HSRPASTHT-TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 1391 Query: 748 -VPPTAQQPPPTIPTMIAAASPPSQ---PAVALSTIPGAVPITPPI----TTIAAAP-PP 798 T P + + + S PS+ + +T+PG+ P TP + TT +P P Sbjct: 1392 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKSTTFYTSPRSP 1450 Query: 799 SVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP-PLATNTVSPSLALLANNLSMP 857 T+ + ++ G V E +P +A P T+ +S ++ Sbjct: 1451 DATLSPATTTSSG--VSEESSTSHSQPGS--THTTAFPDSTTTSDLSQEPTTSHSSQGST 1506 Query: 858 TSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKA 905 + L PG++ +Q + GD T DD T S LV+A Sbjct: 1507 EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEA 1551 Score = 62.4 bits (150), Expect = 2e-09 Identities = 152/752 (20%), Positives = 269/752 (35%), Gaps = 63/752 (8%) Query: 108 STHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRP-IAPAPPSTLSLPP 166 ST ++ +P +P + +P + + P T PS P A AP + Sbjct: 2189 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 2248 Query: 167 KVPGQVTVT------MESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG 220 + PG T S + S I ++ PS+ H + + + R + Sbjct: 2249 RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS--- 2305 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP-PV 279 P + LP G+ +S + T P S + A + + SR P Sbjct: 2306 -PGSTEITTLP-GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2363 Query: 280 TTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSR-PTLSIQHPPSAAISIQRPAQS 338 +T + + PA T + + V +++ + R PT S++ RPA + Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFH-SRPAST 2422 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSAT--TAG 396 TT T S + G ++ TG P T + T PS++ T Sbjct: 2423 H--TTLFTEDSTTS-GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 2479 Query: 397 SVSHTQAPTSTIVTMTVPSHSSHATAVTTS--NIPVAKVVPQQIT--HTSPRIQPDYPAE 452 ++S ++ TS +V + PS S ++ TT+ P + ++ T +TSPR PD Sbjct: 2480 TLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR-SPD---- 2534 Query: 453 RSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTY------TP 506 ++L P + + + + + S + F T S + +H+ T Sbjct: 2535 -ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2593 Query: 507 ITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN-PMQLMTVDASHARHIQGIQPAP 565 + +S +T S + +S + T + ST L+ + T +S + P Sbjct: 2594 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS 2653 Query: 566 ISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG----LQPAPMGTQQPQPEGKTSAV 621 ++ GI A +P T S+T QG Q P T T+ Sbjct: 2654 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATA 2713 Query: 622 VLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL------RKKP 675 + + T +P S P + PA++T +S ++ S PS R + Sbjct: 2714 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2773 Query: 676 ATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMET 735 T ++ T I P +P + + + SPR P + + + T + V E+ Sbjct: 2774 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR----SPTTTLSPASMTSLGVGEES 2829 Query: 736 VSNQNNDQPTIAVPPTAQQPPPTI---PTMIAAASPPSQ-----PAVALSTIPGAVPIT- 786 ++++ T + A P + T + ++SP S P +++ G P T Sbjct: 2830 TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTF 2889 Query: 787 ---PPITTIAAAPPPSVTVGGSLSSVLGPPVP 815 P T S T G + S P P Sbjct: 2890 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 2921 Score = 62.0 bits (149), Expect = 3e-09 Identities = 197/946 (20%), Positives = 317/946 (33%), Gaps = 157/946 (16%) Query: 4 PRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAAT 63 PR P A A G + S Q ST + P SG + P + Sbjct: 4087 PRSPDATLSPATTTSSGVSEESSTSHSQ-----PGSTHTTAFPDSTTTSGLSQ--EPTTS 4139 Query: 64 VNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTA 123 + + ++ +S +SS QS P T V ++TP + Sbjct: 4140 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSST 4199 Query: 124 PPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIA----PAPPSTLSLPPKVPGQVTVTMESS 179 H T S S GL + T S P + P+PPST ++P +V + SS Sbjct: 4200 GSLHTTLTPASSTSTGLQEE--STTFQSWPSSSDTTPSPPSTTAVPVEV-STTYHSRPSS 4256 Query: 180 IPQASAIPVATISGQQGHPSNLHH--------IMTTNVQMSIIRSNAPGPPLHIGASH-- 229 P +T G+ + +H + T S++ P+ G++ Sbjct: 4257 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETT 4316 Query: 230 -LPRGAAAAAVMSSSKVT---------TVLRPTSQLPNAAT-------AQPAVQHIIHQP 272 LP G+ A +S T T L P S + + ++P H P Sbjct: 4317 ALP-GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFP 4375 Query: 273 IQSRPP-----VTTSNAIPPAVVATVS--ATRAQSPVITTTAAHATDSALSRPTLSIQHP 325 + P T S++ P + T+S +T A S +T H++ + L Sbjct: 4376 SSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 4435 Query: 326 PSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPIL- 384 S + P S + TL PA T +Q T Q S T A T Sbjct: 4436 ASGLLEASTPVHSSTGSPHTTL--SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 4493 Query: 385 --------------ATNTIPSATTAG-SVSHTQAPTSTIVTMTVPS-------------- 415 T+ S+TT G S T +S + T T PS Sbjct: 4494 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 4553 Query: 416 --HSSHATAVT----TSNIPVAKVVPQQITHTS-PRIQPDYPAERSSLI--PISGHRASP 466 HSS + T SN + +H+S P+ S+L+ P S H +SP Sbjct: 4554 TYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH-SSP 4612 Query: 467 NPVA-------------METRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVST 513 A E + + S LP ++ L T +PI+S Sbjct: 4613 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 4672 Query: 514 IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI-Q 572 P S P + + T S+ + + + +P++T Sbjct: 4673 TTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 4732 Query: 573 PAPIGTPGI-------QPAPLGTQGIHSATPINTQGLQPAPMGTQQ------PQPEGKTS 619 PA T G+ +P TQ +H G + P TS Sbjct: 4733 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 4792 Query: 620 AVVLADGATIVANPISNPFSAAP-AATTVVQTHSQSASTNAP-AQGSSPRP--------- 668 A+V + + ++P S + P ++TT ++ +AS ++P G +P P Sbjct: 4793 ALV-EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 4851 Query: 669 --------------SILRKKPATDGMAVRKTLI---PPQPPDVASPRVESSMRSTSGSPR 711 + L T G++ + T++ P SP +SM S+S S Sbjct: 4852 AESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSP---ASMTSSSISGE 4908 Query: 712 PAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAA---ASP 768 P ++E + A P + + +S ++ + P +I T A +P Sbjct: 4909 PTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTP 4968 Query: 769 PSQPAVALSTIPGAVPITPPI----TTIAAAPPPSVTVGGSLSSVL 810 SQP ALST+ A P + TT ++P + T S S+ + Sbjct: 4969 HSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTM 5014 Score = 60.8 bits (146), Expect = 7e-09 Identities = 148/725 (20%), Positives = 257/725 (35%), Gaps = 84/725 (11%) Query: 108 STHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRP-IAPAPPSTLSLPP 166 ST ++ +P +P + +P + + P T PS P A AP + Sbjct: 2663 STRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYH 2722 Query: 167 KVPGQVTVT------MESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG 220 + PG T S + S I ++ PS+ H + + + R + Sbjct: 2723 RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS--- 2779 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP-PV 279 P + LP G+ +S + T P S + A + + SR P Sbjct: 2780 -PGSTEITTLP-GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2837 Query: 280 TTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSR 339 +T + + PA T + + V +++ + R T + RPA + Sbjct: 2838 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTH 2897 Query: 340 DVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSAT--TAGS 397 TT T S + G ++ TG P T + T PS++ T + Sbjct: 2898 --TTLFTEDSTTS-GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT 2954 Query: 398 VSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLI 457 +S ++ TS +V + PS S ++ TT+ +P + P S + Y + RS Sbjct: 2955 LSPARSTTSGLVGESTPSRLSPSSTETTT-LPGSPTTPS----LSEKSTTFYTSPRSPDA 3009 Query: 458 PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT-PITSSVSTIRQ 516 +S + + V+ E+ + + + P + HT P +++ S + Q Sbjct: 3010 TLSPATTTSSGVSEESSTSH------------------SQPGSTHTTAFPDSTTTSGLSQ 3051 Query: 517 YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPI 576 P ++ + + A G + L Q T +S + P T G+ A Sbjct: 3052 EPTASHSSQGSTEATLSPGSTTASSLG-QQSTTFHSSPGDTETTLLPDDTITSGLVEAS- 3109 Query: 577 GTPGIQPAPLGTQGIHSA-TPIN--TQGLQPAPMGTQQ--------PQPEGKTSAVVLAD 625 P T +H+ TP + + GLQ Q P P G T+A V Sbjct: 3110 -----TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEV- 3163 Query: 626 GATIVANPISNPFSAAPAATTVV-------QTHSQSASTNAPAQGSSPRPSILRKKPATD 678 T + P S P + A++T + HS +T + S+L +P T Sbjct: 3164 STTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 3223 Query: 679 GMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSN 738 ++ T P + + + SPR P + + + T VS E+ ++ Sbjct: 3224 PISSGSTETTALPGSTTTAGLSEKSTTFYSSPR----SPDTTLSPASTTSSGVSEESTTS 3279 Query: 739 QNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPIT--PPITTIAAAP 796 + T TA T+P + SQ + A + PG+ T P TT ++ Sbjct: 3280 HSRPGST---HTTAFPGSTTMPGV-------SQESTASHSSPGSTDTTLSPGSTTASSLG 3329 Query: 797 PPSVT 801 P S T Sbjct: 3330 PESTT 3334 Score = 57.0 bits (136), Expect = 9e-08 Identities = 175/860 (20%), Positives = 281/860 (32%), Gaps = 138/860 (16%) Query: 79 HMSSSSSLQSREEKQEPVVVRP-------YPQVQMLSTHHAVASATPVA-----VTAPPA 126 H S+SS+ R E+ V P +P S + +P++ TA P Sbjct: 1621 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 1680 Query: 127 HLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPK---------------VPGQ 171 T A SE P P ++PA ++ + + PG Sbjct: 1681 STTTA---GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS 1737 Query: 172 VT---VTMESSIPQASA-------IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP 221 T V+ ES+ +S P +T + G S H + + +++ N Sbjct: 1738 TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS 1797 Query: 222 -------PLH--IGASHLPRGAAAAAVMSSSKVTTVLRPTSQ-----LPNAATAQPAVQH 267 P+H G+ H A + T P+S+ P +A + Sbjct: 1798 GLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELST 1857 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA---AHATDSALSRPTLSIQH 324 H S P S + + S T SPV T T A +T S L + + Sbjct: 1858 TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS 1917 Query: 325 PPSAAISIQRP------AQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA 378 P + ++ P +S + T + +H P + + T + + A Sbjct: 1918 SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTAT 1977 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIV---------------TMTVPSHSSHATAV 423 T P +T + S + S S +Q T TIV T + S S TA+ Sbjct: 1978 THFPDSSTTSGRSEESTASHS-SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 2036 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 S H+SPR + ++L P S S T S +RP Sbjct: 2037 PGSTTTPGLSEKSTTFHSSPR------SPATTLSPAS--TTSSGVSEESTTSHSRPGSTH 2088 Query: 484 QFQYFLPTYPP--SAYPLAAHTY------TPITSSVSTIRQYPVSAQAPNSAITAQTGVG 535 + T P S + +H+ T + +S +T S + +S + T + Sbjct: 2089 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALS 2148 Query: 536 VASTVHLN-PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSA 594 ST L+ + T +S + P ++ GI A +P T S+ Sbjct: 2149 PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS 2208 Query: 595 TPINTQG----LQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQT 650 T QG Q P T T+ + + T +P S P + PA++T Sbjct: 2209 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST---- 2264 Query: 651 HSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSP 710 G S + +I P G P S R ES+ S Sbjct: 2265 ----------TSGHSEKSTIFHSSPDASGTT------PSSAHSTTSGRGESTTSRIS--- 2305 Query: 711 RPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPS 770 G+ + + S TP T + PT + P + ++ + + S Sbjct: 2306 --PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM---TSLGVGEESTTSRS 2360 Query: 771 QPAVALSTIPGAVPITPPI----TTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPM 826 QP ST+ A TP + TT+ ++ P GS + + P P V+ E Sbjct: 2361 QPGSTHSTVSPASTTTPGLSEESTTVYSSSP------GSTETTVFPRTPTTSVRGEEPTT 2414 Query: 827 DIMRPVSAVPPLATNTVSPS 846 RP S L T + S Sbjct: 2415 FHSRPASTHTTLFTEDSTTS 2434 Score = 55.1 bits (131), Expect = 4e-07 Identities = 157/789 (19%), Positives = 265/789 (33%), Gaps = 113/789 (14%) Query: 79 HMSSSSSLQSREEKQEPVVVRP-------YPQVQMLSTHHAVASATPVA-----VTAPPA 126 H S+SS+ R E+ V P +P S + +P++ TA P Sbjct: 3178 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 3237 Query: 127 HLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPK---------------VPGQ 171 T A SE P P ++PA ++ + + PG Sbjct: 3238 STTTA---GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS 3294 Query: 172 VT---VTMESSIPQASA-------IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP 221 T V+ ES+ +S P +T + G S H + + +++ N Sbjct: 3295 TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTAS 3354 Query: 222 -------PLH--IGASHLPRGAAAAAVMSSSKVTTVLRPTSQ-----LPNAATAQPAVQH 267 P+H G+ H A + T P S+ P +A + Sbjct: 3355 GLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELST 3414 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA---AHATDSALSRPTLSIQH 324 H S P S + + S T SPV T T A +T S L + + Sbjct: 3415 TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHS 3474 Query: 325 PPSAAISIQRP------AQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA 378 P + ++ P + + TT + +H P + + T + + A Sbjct: 3475 SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 3534 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIV---------------TMTVPSHSSHATAV 423 T P +T + S + S S +Q T TIV T + S S TA+ Sbjct: 3535 THFPDSSTTSGRSEESTASHS-SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 3593 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 S H+SPR + ++L P S S T S +RP Sbjct: 3594 PGSTTTPGLSEKSTTFHSSPR------SPATTLSPAS--TTSSGVSEESTTSHSRPGSTH 3645 Query: 484 QFQYFLPTYPP--SAYPLAAHTY------TPITSSVSTIRQYPVSAQAPNSAITAQTGVG 535 + T P S + +H+ T + +S +T S + +S+ + T + Sbjct: 3646 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALS 3705 Query: 536 VASTVHLN-PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSA 594 ST L+ + T +S + P ++ GI A +P T S+ Sbjct: 3706 PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS 3765 Query: 595 TPINTQG----LQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQT 650 T QG Q P T T+ + + T +P S P + PA++T Sbjct: 3766 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH 3825 Query: 651 HSQSASTNAPAQGSSPRPSIL------RKKPATDGMAVRKTLIPPQPPDVASPRVESSMR 704 +S ++ S PS R + T ++ T I P +P + + Sbjct: 3826 SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 3885 Query: 705 STSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTI---PT 761 + SPR P + + + T + V E+ ++++ T + A P + T Sbjct: 3886 TFYSSPR----SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEEST 3941 Query: 762 MIAAASPPS 770 + ++SP S Sbjct: 3942 TVYSSSPGS 3950 Score = 52.0 bits (123), Expect = 3e-06 Identities = 152/720 (21%), Positives = 253/720 (35%), Gaps = 100/720 (13%) Query: 108 STHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS-RPIAPAPPSTLSLPP 166 +T + ++TPV + H T + P S + +P + PS + +PAP T S Sbjct: 384 TTSGLLEASTPVHSSTGSPHTTLS-PSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFV 442 Query: 167 KVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 K+ + T SS + S GH +T V S + + PP Sbjct: 443 KL----STTYHSSPSSTPTTHFSASSTTLGHSEE-----STPVHSSPVATATTPPPARSA 493 Query: 227 AS-HLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI 285 S H+ A S++ T+ P S + + + A H +S P TT+ Sbjct: 494 TSGHVEESTAYHRSPGSTQ--TMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 551 Query: 286 PPAVVATVSATRA----QSPVIT-----TTAAHATDSALSRPTLSIQHPPSAAISIQRPA 336 + +++ +T S I+ + A+H++ A++ L PS + P+ Sbjct: 552 HTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPS 611 Query: 337 QSRDVTTRIT-LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTA 395 + T LP T K L + S +P A + ++ +TT+ Sbjct: 612 PISSGSMETTALPG----STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS 667 Query: 396 ----GSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPA 451 GS T P ST T+P S +TA +S P + T T+ + P+Y Sbjct: 668 HSRPGSTHTTAFPGST----TMPGLSQESTASHSSPGPTDTTLSPGST-TASSLGPEYTT 722 Query: 452 ERS-------SLIP----ISGHRASPNPVAMETRSDNR---PSVPVQFQYFLPTY----- 492 S +L+P SG + PV TRS + P+ Q T+ Sbjct: 723 FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS 782 Query: 493 -------PPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 PP+ T S S+I +SA++ S + ++ +S M Sbjct: 783 SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 842 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPA 605 D + R + +T I AP T + P + ++P +T Sbjct: 843 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS----YHSSPGSTATTHFP 898 Query: 606 PMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSS 665 T + E T++ D + P A + T+V+ ST +P S Sbjct: 899 DSSTTSGRSEESTASHSSQDATGTIVLP-------ARSTTSVL----LGESTTSPISSGS 947 Query: 666 PRPSILRKKPATDGMAVRKTLI---PPQPPDVASPRVESSM----RSTSGSPRPAGAKPK 718 + L T G++ R T P P SP +S ST+ RP G+ Sbjct: 948 METTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRP-GSTHT 1006 Query: 719 SEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALST 778 + S TP T S+ + P T T++ A++ S P+ +T Sbjct: 1007 TAFPDSTTTPGLSRHSTTSHSS--------------PGSTDTTLLPASTTTSGPSQESTT 1052 Score = 49.7 bits (117), Expect = 2e-05 Identities = 119/581 (20%), Positives = 203/581 (34%), Gaps = 62/581 (10%) Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPI--QSRPPVTTSNAIPPAVV 290 G+ A +S T P S + A+ + + SRP T + A P + Sbjct: 269 GSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 328 Query: 291 -------ATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTT 343 +T S + S T + T S+L + + P + + P D TT Sbjct: 329 MPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLP----DNTT 384 Query: 344 RITL-----PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAG-- 396 L P H + G+P L + T G P + T+ PS TT+ Sbjct: 385 TSGLLEASTPVHSSTGSPHTTLSPSSSTT--HEGEPTTFQSWPSSKDTSPAPSGTTSAFV 442 Query: 397 --SVSHTQAPTSTIVT-----MTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 S ++ +P+ST T T HS +T V +S + A P + TS ++ Sbjct: 443 KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEEST 502 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS 509 RS + H P S+ + + + P + LA +Y Sbjct: 503 AYHRSPGSTQTMH--FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLG 560 Query: 510 SVSTIR---QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI 566 S T +S ++ S + + +A+TV + ++ + + P+PI Sbjct: 561 STETTHFRDSSTISGRSEESKASHSSPDAMATTV-------LPAGSTPSVLVGDSTPSPI 613 Query: 567 STQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG 626 S+ ++ + PG P G+ + T P T P TS+ V + Sbjct: 614 SSGSMETTAL--PGSTTKP----GLSEKS--TTFYSSPRSPDTTH-LPASMTSSGVSEES 664 Query: 627 ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTL 686 T + P S +A P +TT+ S + A SSP P+ P G +L Sbjct: 665 TTSHSRPGSTHTTAFPGSTTM-----PGLSQESTASHSSPGPTDTTLSP---GSTTASSL 716 Query: 687 IPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATP-VTVSMETVSNQNNDQPT 745 P + P + + + +H S +P T+S + + + T Sbjct: 717 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 776 Query: 746 IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPIT 786 P+++ P PT +A PS + P ++P T Sbjct: 777 FHSWPSSKDTRPAPPTTTSAFVEPSTTS---HGSPSSIPTT 814 Score = 48.5 bits (114), Expect = 3e-05 Identities = 173/816 (21%), Positives = 280/816 (34%), Gaps = 123/816 (15%) Query: 29 SQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQS 88 S FP + STG +P++ SG G P+ S +E + + S + S Sbjct: 4024 STTFPS-SSGSTGTKLSPARSTTSGLVGESTPSRL----SPSSTETTT---LPGSPTTPS 4075 Query: 89 REEKQEPVVVRPYPQVQMLS----THHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPP 144 EK P LS T V+ + + + P + T A P S + + Sbjct: 4076 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 4135 Query: 145 PKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI--PQASAIPVATISGQQGHPSNLH 202 P + S+ A S S GQ + T SS + + +P TI+ S Sbjct: 4136 PTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 4195 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 H T ++ ++ P ++ L + SS TT P++ TA Sbjct: 4196 HSSTGSLHTTLT-------PASSTSTGLQEESTTFQSWPSSSDTTPSPPST------TAV 4242 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS-PVITTTAAHATDSALS----R 317 P + S P T +A + + +T S P T TA T SA S Sbjct: 4243 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 4302 Query: 318 PTLSIQHPPSAAISIQRPAQSRDVTTR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVA 376 PT S P ++ S + A TT ++ S +P+ T++ + S+G Sbjct: 4303 PTTS----PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 4358 Query: 377 AATVAP---ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKV 433 + T + T PS+TT VS T + S S T ++ + + + Sbjct: 4359 STTSHSRPGSMHTTAFPSSTTMPGVSQES-------TASHSSPGSTDTTLSPGSTTASSL 4411 Query: 434 VPQQIT-HTSP-----RIQPDYPAERSSL---IPISGHRASPNPVAMETRSDNRPSVPVQ 484 P+ T H+SP + PD L P+ SP+ S R Sbjct: 4412 GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 4471 Query: 485 FQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNP 544 FQ ++P S A P T++ + + S +P+S T T +ST Sbjct: 4472 FQ----SWPNSKDTTPA----PPTTTSAFVELSTTSHGSPSS--TPTTHFSASSTTLGRS 4521 Query: 545 MQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQP 604 + TV +S PA +T G+ + +P TQ +H T G Sbjct: 4522 EESTTVHSSPVATATTPSPARSTTSGLVEE---STTYHSSPGSTQTMHFPESNTTSG--- 4575 Query: 605 APMGTQQPQPEGKTSAVVLADGAT---IVANPISNPFSAAPAATTVVQTHSQSASTNAPA 661 G + T+ + + +T +V P S + ++P +T TH +ST Sbjct: 4576 --RGEESTTSHSSTTHTISSAPSTTSALVEEPTS--YHSSPGSTAT--THFPDSST---- 4625 Query: 662 QGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSEI 721 T G + T SS +T PA + + Sbjct: 4626 ---------------TSGRSEESTAS------------HSSQDATGTIVLPARSTTSVLL 4658 Query: 722 HVSMATPVTV-SMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 780 S +P++ SMET A+P + P + + +SP S P S Sbjct: 4659 GESTTSPISSGSMETT----------ALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASS 4708 Query: 781 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPE 816 + + TT+ ++P + T S V E Sbjct: 4709 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 4744 Score = 39.3 bits (90), Expect = 0.020 Identities = 124/602 (20%), Positives = 194/602 (32%), Gaps = 101/602 (16%) Query: 349 SHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIP-SATTAG----------- 396 SH G L T G P + + + T +P S TTAG Sbjct: 227 SHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSS 286 Query: 397 ----------------------SVSHTQ-APTSTIV---TMTVPSHSSHATA-------- 422 + SH++ PT TI + T+P S +TA Sbjct: 287 PRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGST 346 Query: 423 ---VTTSNIPVAKVVPQQIT-HTSPRIQ-----PDYPAERSSL---IPISGHRASPNPVA 470 ++ + + P+ T H+SP PD L P+ SP+ Sbjct: 347 DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTL 406 Query: 471 METRSDNRPSVPVQFQYFLPTYPPS--AYPLAAHTYTPITSSVSTIRQYPVSAQAPN-SA 527 + S P FQ ++P S P + T + +T P S + SA Sbjct: 407 SPSSSTTHEGEPTTFQ----SWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA 462 Query: 528 ITAQTGVGVAST-VHLNPMQLMT-------VDASHARHIQGIQPAPISTQGIQ-PAPIGT 578 + G ST VH +P+ T + H +P STQ + P T Sbjct: 463 SSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTT 522 Query: 579 PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPF 638 G G + T +T A T G T D +TI + Sbjct: 523 SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA 582 Query: 639 SAA---PAATTVVQTHSQSA-----STNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ 690 S + ATTV+ S + ST +P S + L G++ + T Sbjct: 583 SHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSS 642 Query: 691 PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 750 P + + +SM S+ S + + + A P + +M +S ++ Sbjct: 643 PRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST--------A 694 Query: 751 TAQQPPPTIPTMIAAASPPSQPAVALSTI---PGAVPIT--PPITTIAAAPPPSVTVGGS 805 + P PT T+ ++ S +T PG+ T P TT + S+ V S Sbjct: 695 SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSS 754 Query: 806 LSS---VLGPPVPEIKVKEEV--EPMDIMRPVSAVPPLATNT-VSPSLALLANNLSMPTS 859 S L P + E + PP T+ V PS + S+PT+ Sbjct: 755 TRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT 814 Query: 860 DL 861 + Sbjct: 815 HI 816 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.124 0.355 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 48,758,846 Number of Sequences: 37866 Number of extensions: 2809089 Number of successful extensions: 28249 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 213 Number of HSP's successfully gapped in prelim test: 1310 Number of HSP's that attempted gapping in prelim test: 13878 Number of HSP's gapped (non-prelim): 7900 length of query: 1083 length of database: 18,247,518 effective HSP length: 113 effective length of query: 970 effective length of database: 13,968,660 effective search space: 13549600200 effective search space used: 13549600200 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.