Search of human proteins with 225545550

Search of human proteins with 225545550

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225545550 TEL2, telomere maintenance 2, homolog [Homo
sapiens]
         (837 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225545550 TEL2, telomere maintenance 2, homolog [Homo sapiens]    1630   0.0  
gi|57634534 nucleoporin 205kDa [Homo sapiens]                          35   0.29 
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]        34   0.64 
gi|34878716 paired box protein 2 isoform d [Homo sapiens]              33   1.1  
gi|34878701 paired box protein 2 isoform b [Homo sapiens]              33   1.1  
gi|34878709 paired box protein 2 isoform c [Homo sapiens]              33   1.1  
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]       33   1.1  
gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]              33   1.1  
gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]              33   1.1  
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    33   1.1  
gi|51173735 ras responsive element binding protein 1 isoform 2 [...    33   1.4  
gi|51173737 ras responsive element binding protein 1 isoform 1 [...    33   1.4  
gi|39995084 integrator complex subunit 3 [Homo sapiens]                33   1.4  
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]           32   1.9  
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]           32   1.9  
gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ...    32   1.9  
gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ...    32   1.9  
gi|222136634 tetratricopeptide repeat domain 26 isoform 1 [Homo ...    32   1.9  
gi|222136607 tetratricopeptide repeat domain 26 isoform 3 [Homo ...    32   1.9  
gi|222136605 tetratricopeptide repeat domain 26 isoform 2 [Homo ...    32   1.9  
gi|116517292 cut-like 2 [Homo sapiens]                                 32   2.4  
gi|33383235 minichromosome maintenance complex component 10 isof...    32   2.4  
gi|153792351 ADAM metallopeptidase with thrombospondin type 1 mo...    32   2.4  
gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo ...    32   3.2  
gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo ...    32   3.2  
gi|170784831 chromosome 1 open reading frame 9 protein isoform 2...    32   3.2  
gi|109637771 calpastatin isoform l [Homo sapiens]                      31   4.2  
gi|109637769 calpastatin isoform k [Homo sapiens]                      31   4.2  
gi|109637767 calpastatin isoform j [Homo sapiens]                      31   4.2  
gi|109637765 calpastatin isoform i [Homo sapiens]                      31   4.2  

>gi|225545550 TEL2, telomere maintenance 2, homolog [Homo sapiens]
          Length = 837

 Score = 1630 bits (4220), Expect = 0.0
 Identities = 837/837 (100%), Positives = 837/837 (100%)

Query: 1   MEPAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPALPREKEEFASAHFS 60
           MEPAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPALPREKEEFASAHFS
Sbjct: 1   MEPAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPALPREKEEFASAHFS 60

Query: 61  PVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKM 120
           PVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKM
Sbjct: 61  PVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKM 120

Query: 121 ARLLARFLREGRLAVLMEAQCRQQTQPGFILLRETLLGKVVALPDHLGNRLQQENLAEFF 180
           ARLLARFLREGRLAVLMEAQCRQQTQPGFILLRETLLGKVVALPDHLGNRLQQENLAEFF
Sbjct: 121 ARLLARFLREGRLAVLMEAQCRQQTQPGFILLRETLLGKVVALPDHLGNRLQQENLAEFF 180

Query: 181 PQNYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQEILGVLVPRLAA 240
           PQNYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQEILGVLVPRLAA
Sbjct: 181 PQNYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQEILGVLVPRLAA 240

Query: 241 LTQGSYLHQRVCWRLVEQVPDRAMEAVLTGLVEAALGPEVLSRLLGNLVVKNKKAQFVMT 300
           LTQGSYLHQRVCWRLVEQVPDRAMEAVLTGLVEAALGPEVLSRLLGNLVVKNKKAQFVMT
Sbjct: 241 LTQGSYLHQRVCWRLVEQVPDRAMEAVLTGLVEAALGPEVLSRLLGNLVVKNKKAQFVMT 300

Query: 301 QKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQRHV 360
           QKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQRHV
Sbjct: 301 QKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQRHV 360

Query: 361 SKAVLICLAQLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPE 420
           SKAVLICLAQLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPE
Sbjct: 361 SKAVLICLAQLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPE 420

Query: 421 GPPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQA 480
           GPPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQA
Sbjct: 421 GPPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQA 480

Query: 481 QLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEG 540
           QLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEG
Sbjct: 481 QLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEG 540

Query: 541 LVYRSPTATREVSVELAKVLLHLEEKTCVVGFAGLRQRALVAVTVTDPAPVADYLTSQFY 600
           LVYRSPTATREVSVELAKVLLHLEEKTCVVGFAGLRQRALVAVTVTDPAPVADYLTSQFY
Sbjct: 541 LVYRSPTATREVSVELAKVLLHLEEKTCVVGFAGLRQRALVAVTVTDPAPVADYLTSQFY 600

Query: 601 ALNYSLRQRMDILDVLTLAAQELSRPGCLGRTPQPGSPSPNTPCLPEAAVSQPGSAVASD 660
           ALNYSLRQRMDILDVLTLAAQELSRPGCLGRTPQPGSPSPNTPCLPEAAVSQPGSAVASD
Sbjct: 601 ALNYSLRQRMDILDVLTLAAQELSRPGCLGRTPQPGSPSPNTPCLPEAAVSQPGSAVASD 660

Query: 661 WRVVVEERIRSKTQRLSKGGPRQGPAGSPSRFNSVAGHFFFPLLQRFDRPLVTFDLLGED 720
           WRVVVEERIRSKTQRLSKGGPRQGPAGSPSRFNSVAGHFFFPLLQRFDRPLVTFDLLGED
Sbjct: 661 WRVVVEERIRSKTQRLSKGGPRQGPAGSPSRFNSVAGHFFFPLLQRFDRPLVTFDLLGED 720

Query: 721 QLVLGRLAHTLGALMCLAVNTTVAVAMGKALLEFVWALRFHIDAYVRQGLLSAVSSVLLS 780
           QLVLGRLAHTLGALMCLAVNTTVAVAMGKALLEFVWALRFHIDAYVRQGLLSAVSSVLLS
Sbjct: 721 QLVLGRLAHTLGALMCLAVNTTVAVAMGKALLEFVWALRFHIDAYVRQGLLSAVSSVLLS 780

Query: 781 LPAARLLEDLMDELLEARSWLADVAEKDPDEDCRTLALRALLLLQRLKNRLLPPASP 837
           LPAARLLEDLMDELLEARSWLADVAEKDPDEDCRTLALRALLLLQRLKNRLLPPASP
Sbjct: 781 LPAARLLEDLMDELLEARSWLADVAEKDPDEDCRTLALRALLLLQRLKNRLLPPASP 837


>gi|57634534 nucleoporin 205kDa [Homo sapiens]
          Length = 2012

 Score = 35.0 bits (79), Expect = 0.29
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 317 SLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQRHVSKAVLICLAQLGEPEL 376
           SL+ HL  +S    L L +L+E     G      + P P ++H+ KAV  CLA L     
Sbjct: 804 SLMYHLLNESPMLELALSLLEE-----GVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQ 858

Query: 377 RDS--RDELLASMMAGVKCRLDSSL 399
           +++   D L  S +A + C L+  L
Sbjct: 859 KENLFMDLLRESQLALIVCPLEQLL 883


>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
          Length = 506

 Score = 33.9 bits (76), Expect = 0.64
 Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 12/108 (11%)

Query: 619 AAQELSRPGCLGRTPQPGSPSPNTPCL-------PEAAVSQPGSAVASDWRVVVEERIRS 671
           A ++     C+  TP+        P +       P+A  ++  +AV    + V EER++ 
Sbjct: 232 AEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRETHKRVPEERLQD 291

Query: 672 KT--QRLSKGGP-RQGPAGSPSRFNSVAGHF--FFPLLQRFDRPLVTF 714
               +R  KG P R+ P G P  +  V  +     P++Q++D P++ F
Sbjct: 292 SVDLKRARKGKPKREDPKGIPDYWLIVLKNVDKLGPMIQKYDEPILKF 339


>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
          Length = 408

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 42/187 (22%), Positives = 70/187 (37%), Gaps = 44/187 (23%)

Query: 380 RDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYEEDELSLELLA 439
           RD LLA  +       + ++P V  +  I+   V    HP                    
Sbjct: 115 RDRLLAEGICD-----NDTVPSVSSINRIIRTKVQQPFHP-------------------- 149

Query: 440 LASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDG--------GVPQAQLAGSDSDLDS 491
             +P  AG G +  G ++VP+TA PP  + +    G        G+P++       D D 
Sbjct: 150 --TPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDV 207

Query: 492 DDEFVPY--DMSG-DRELKSSKAPAYVRDCVEAL------TTSEDIERWEAALRALEGLV 542
            +  VP     SG D   K  +A  + +  +EAL       +  D+ +    +++ +G  
Sbjct: 208 SEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNE 267

Query: 543 YRSPTAT 549
           Y  P  T
Sbjct: 268 YSLPALT 274


>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
          Length = 393

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 42/187 (22%), Positives = 70/187 (37%), Gaps = 44/187 (23%)

Query: 380 RDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYEEDELSLELLA 439
           RD LLA  +       + ++P V  +  I+   V    HP                    
Sbjct: 115 RDRLLAEGICD-----NDTVPSVSSINRIIRTKVQQPFHP-------------------- 149

Query: 440 LASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDG--------GVPQAQLAGSDSDLDS 491
             +P  AG G +  G ++VP+TA PP  + +    G        G+P++       D D 
Sbjct: 150 --TPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDV 207

Query: 492 DDEFVPY--DMSG-DRELKSSKAPAYVRDCVEAL------TTSEDIERWEAALRALEGLV 542
            +  VP     SG D   K  +A  + +  +EAL       +  D+ +    +++ +G  
Sbjct: 208 SEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNE 267

Query: 543 YRSPTAT 549
           Y  P  T
Sbjct: 268 YSLPALT 274


>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
          Length = 396

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 42/187 (22%), Positives = 70/187 (37%), Gaps = 44/187 (23%)

Query: 380 RDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYEEDELSLELLA 439
           RD LLA  +       + ++P V  +  I+   V    HP                    
Sbjct: 115 RDRLLAEGICD-----NDTVPSVSSINRIIRTKVQQPFHP-------------------- 149

Query: 440 LASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDG--------GVPQAQLAGSDSDLDS 491
             +P  AG G +  G ++VP+TA PP  + +    G        G+P++       D D 
Sbjct: 150 --TPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDV 207

Query: 492 DDEFVPY--DMSG-DRELKSSKAPAYVRDCVEAL------TTSEDIERWEAALRALEGLV 542
            +  VP     SG D   K  +A  + +  +EAL       +  D+ +    +++ +G  
Sbjct: 208 SEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNE 267

Query: 543 YRSPTAT 549
           Y  P  T
Sbjct: 268 YSLPALT 274


>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
          Length = 867

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 17/55 (30%), Positives = 26/55 (47%)

Query: 425 KFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQ 479
           K+Q   +    E   L +PQ   +G  E G  L+P   E  ++  +E+ DG  PQ
Sbjct: 287 KYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEMCDGEEPQ 341


>gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]
          Length = 1523

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 46/175 (26%), Positives = 63/175 (36%), Gaps = 15/175 (8%)

Query: 312  TPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTP--LPQQRHVSKAVLICLA 369
            TPM    L +  +DS     L  +L E   +     A R  P  LPQQ+  S+A  + L 
Sbjct: 887  TPMKPESLENSILDSLEPQSLASLLSE---SESPQEAGRGHPSFLPQQKESSEASELILY 943

Query: 370  QLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYE 429
             L          E+  +      CR +    P  + G     V S     + PP      
Sbjct: 944  SL--------EAEVTVTGTDSQYCRKEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGES 995

Query: 430  EDELSLELLALASPQPAGDGASEAGTSL--VPATAEPPAETPAEIVDGGVPQAQL 482
            E +L     A+ SP P  D A    TSL   P  A P  +  +      VP + L
Sbjct: 996  EADLECSFAAIHSPAPPPDPAPRFATSLPHFPGCAGPTEDELSLPEGPSVPSSSL 1050


>gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
          Length = 1518

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 46/175 (26%), Positives = 63/175 (36%), Gaps = 15/175 (8%)

Query: 312  TPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTP--LPQQRHVSKAVLICLA 369
            TPM    L +  +DS     L  +L E   +     A R  P  LPQQ+  S+A  + L 
Sbjct: 887  TPMKPESLENSILDSLEPQSLASLLSE---SESPQEAGRGHPSFLPQQKESSEASELILY 943

Query: 370  QLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYE 429
             L          E+  +      CR +    P  + G     V S     + PP      
Sbjct: 944  SL--------EAEVTVTGTDSQYCRKEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGES 995

Query: 430  EDELSLELLALASPQPAGDGASEAGTSL--VPATAEPPAETPAEIVDGGVPQAQL 482
            E +L     A+ SP P  D A    TSL   P  A P  +  +      VP + L
Sbjct: 996  EADLECSFAAIHSPAPPPDPAPRFATSLPHFPGCAGPTEDELSLPEGPSVPSSSL 1050


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 61/234 (26%), Positives = 88/234 (37%), Gaps = 54/234 (23%)

Query: 319 LGHLAMDSQRRPLL--LQVLKELLETWGSSSAIRHTPLPQQRHVSKAVLICLAQLGEPEL 376
           LG L  D+ RR  L  +Q    LL    S S      LP  R  S+   + +++L  P+ 
Sbjct: 289 LGELDRDALRRSRLRKVQTFPRLL----SDSPEATLCLPLTRGKSQ---LPISELFSPDP 341

Query: 377 RDS---RDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYEEDEL 433
           R +   R   L+S  A  KCRL     P  +LG +     + R    GP +         
Sbjct: 342 RKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPC---AGRSTDRGPGV--------- 389

Query: 434 SLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQLAGSDSDLDSDD 493
                      P   G  E         ++ PAE PA+  D        A  ++    DD
Sbjct: 390 -----------PGSPGQPETS-----HPSQGPAEAPADPRD--------ASGEAQTPRDD 425

Query: 494 EFVPYDMSGDRELKSSKAPAYV--RDCVEAL-TTSEDIERWEAALRALEGLVYR 544
           E +P    G R+L+S+ A  +V  +D +  L     + E W   L  L  L  R
Sbjct: 426 ERIP---EGARQLESAAAEQWVSLQDLLSQLGRPFREYELWALCLACLRALQTR 476


>gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1687

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 447  GDGAS--EAGTSLVPATAEPPAETPAEIVD----GGVPQAQLAGSDSDLDSDDEFVPYDM 500
            GDGAS  E G    P   E P ETPAE+V+     G   A+    +++  SD E      
Sbjct: 1425 GDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKR 1484

Query: 501  SGDR 504
            S ++
Sbjct: 1485 SSEK 1488


>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1742

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 447  GDGAS--EAGTSLVPATAEPPAETPAEIVD----GGVPQAQLAGSDSDLDSDDEFVPYDM 500
            GDGAS  E G    P   E P ETPAE+V+     G   A+    +++  SD E      
Sbjct: 1480 GDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKR 1539

Query: 501  SGDR 504
            S ++
Sbjct: 1540 SSEK 1543


>gi|39995084 integrator complex subunit 3 [Homo sapiens]
          Length = 1042

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 52/206 (25%), Positives = 84/206 (40%), Gaps = 26/206 (12%)

Query: 180 FPQNYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQEILGVLVPRLA 239
           FP    R    E++ ++ AV+DS Q         V  V+    V  R+  +L +L+  L 
Sbjct: 749 FPDETLR--SGELLNMIVAVIDSAQ-----LQELVCHVMMGNLVMFRKDSVLNILIQSLD 801

Query: 240 ALTQGSYLHQRVCWRL--VEQVPDRAMEAVLTGLVEAALGPEVLSRLLGNLVVKNKKAQF 297
             T      Q   W+L     +P   +  +L  L +    PE LS LL  L ++ +K   
Sbjct: 802 WET----FEQYCAWQLFLAHNIPLETIIPILQHL-KYKEHPEALSCLL--LQLRREKPSE 854

Query: 298 VMTQKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQ 357
            M + +L            S+L H  M      LL + +K LL        I++  LP++
Sbjct: 855 EMVKMVLSRPCHPDDQFTTSILRHWCMKHDE--LLAEHIKSLL--------IKNNSLPRK 904

Query: 358 RHVSKAVLICLAQLGEPELRDSRDEL 383
           R   ++    LAQL   ++ +  D L
Sbjct: 905 RQSLRSSSSKLAQLTLEQILEHLDNL 930


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 3    PAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPA--LPREKEEFASAHFS 60
            PAP++      + + +LSS+   G    TL +L+R LGE+ PP+  L  E+ + A    +
Sbjct: 3483 PAPTQDTHMETDLLSSLSSTP--GEKTETL-ALQR-LGELGPPSPGLNWEQPQAARLSRT 3538

Query: 61   PVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKM 120
             ++  L  RL PAW   L HG       S  L   A      +  +       ++ L   
Sbjct: 3539 GLVEGLRKRLLPAWCASLAHG------LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSS 3592

Query: 121  ARLLARFLREGRLAVLMEA 139
            A  LA FL    L VL+EA
Sbjct: 3593 ASFLASFLGWEPLKVLLEA 3611


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 3    PAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPA--LPREKEEFASAHFS 60
            PAP++      + + +LSS+   G    TL +L+R LGE+ PP+  L  E+ + A    +
Sbjct: 3484 PAPTQDTHMETDLLSSLSSTP--GEKTETL-ALQR-LGELGPPSPGLNWEQPQAARLSRT 3539

Query: 61   PVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKM 120
             ++  L  RL PAW   L HG       S  L   A      +  +       ++ L   
Sbjct: 3540 GLVEGLRKRLLPAWCASLAHG------LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSS 3593

Query: 121  ARLLARFLREGRLAVLMEA 139
            A  LA FL    L VL+EA
Sbjct: 3594 ASFLASFLGWEPLKVLLEA 3612


>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
           sapiens]
          Length = 870

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 8/76 (10%)

Query: 623 LSRPGCLGRTPQPGSPSPNTPC------LPEAAVSQPGSAVASDWRVVVEERIRSKT--Q 674
           L  PG  G  P PG  S  TPC        EA ++     V     +    R R  T   
Sbjct: 685 LRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAA 744

Query: 675 RLSKGGPRQGPAGSPS 690
            L KG PR+ P  SP+
Sbjct: 745 ALRKGAPREQPPASPA 760


>gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
           sapiens]
          Length = 538

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 8/76 (10%)

Query: 623 LSRPGCLGRTPQPGSPSPNTPC------LPEAAVSQPGSAVASDWRVVVEERIRSKT--Q 674
           L  PG  G  P PG  S  TPC        EA ++     V     +    R R  T   
Sbjct: 353 LRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAA 412

Query: 675 RLSKGGPRQGPAGSPS 690
            L KG PR+ P  SP+
Sbjct: 413 ALRKGAPREQPPASPA 428


>gi|222136634 tetratricopeptide repeat domain 26 isoform 1 [Homo
           sapiens]
          Length = 554

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 14/112 (12%)

Query: 183 NYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQE-ILGVLVPRLAAL 241
           N+FRL      R  +A + SL     SS  F  +++    V  R  E  L VL P +  +
Sbjct: 228 NHFRLYNG---RAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVI 284

Query: 242 TQGS------YLHQ---RVCWRLVEQV-PDRAMEAVLTGLVEAALGPEVLSR 283
            +        YL Q   +  + L++ + P    E +L G+V AALG E+ SR
Sbjct: 285 PEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSR 336


>gi|222136607 tetratricopeptide repeat domain 26 isoform 3 [Homo
           sapiens]
          Length = 523

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 14/112 (12%)

Query: 183 NYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQE-ILGVLVPRLAAL 241
           N+FRL      R  +A + SL     SS  F  +++    V  R  E  L VL P +  +
Sbjct: 197 NHFRLYNG---RAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVI 253

Query: 242 TQGS------YLHQ---RVCWRLVEQV-PDRAMEAVLTGLVEAALGPEVLSR 283
            +        YL Q   +  + L++ + P    E +L G+V AALG E+ SR
Sbjct: 254 PEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSR 305


>gi|222136605 tetratricopeptide repeat domain 26 isoform 2 [Homo
           sapiens]
          Length = 487

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 14/112 (12%)

Query: 183 NYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQE-ILGVLVPRLAAL 241
           N+FRL      R  +A + SL     SS  F  +++    V  R  E  L VL P +  +
Sbjct: 228 NHFRLYNG---RAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVI 284

Query: 242 TQGS------YLHQ---RVCWRLVEQV-PDRAMEAVLTGLVEAALGPEVLSR 283
            +        YL Q   +  + L++ + P    E +L G+V AALG E+ SR
Sbjct: 285 PEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSR 336


>gi|116517292 cut-like 2 [Homo sapiens]
          Length = 1486

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 7/75 (9%)

Query: 416  RIHPEGPPLKFQYEEDELSLELLALASPQPAGD-----GASEAGTSLVPATAEPPAETPA 470
            R+HP+    K   E    SLE+ +L SP  A         S   +S  P +  PP   PA
Sbjct: 1372 RLHPDPLSFKSASESSRCSLEV-SLNSPSAASSPGLMMSVSPVPSSSAPISPSPPGAPPA 1430

Query: 471  EIVDGGVPQAQLAGS 485
            + V    P A +AG+
Sbjct: 1431 K-VPSASPTADMAGA 1444


>gi|33383235 minichromosome maintenance complex component 10 isoform
           2 [Homo sapiens]
          Length = 874

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 60/234 (25%), Positives = 93/234 (39%), Gaps = 33/234 (14%)

Query: 429 EEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQLAGSDSD 488
           EED LSL    L   + A D  SE    L     EP A              +L  +D D
Sbjct: 4   EEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFD------------ELFDADGD 51

Query: 489 LDSDDEFVPYDMSGD-RELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEGLVYRSPT 547
            +S  E      +G+ R+ K + A  +    +E LT  E++     A ++ E  V  +P 
Sbjct: 52  GESYTEEADDGETGETRDEKENLATLF--GDMEDLTDEEEV----PASQSTENRVLPAPA 105

Query: 548 ATRE-VSVELAKVLLHLEEKTCVVGFAGLRQRALVAVTVTDPAPVADYLTSQFYALNYSL 606
             RE  + EL + L +L+E+   +      Q  L   T+   A  A    S   +    L
Sbjct: 106 PRREKTNEELQEELRNLQEQMKAL------QEQLKVTTIKQTASPARLQKSPEKSPRPPL 159

Query: 607 RQ-RMDILDVLTLAAQELSRPGC-----LGRTPQPGSPSP-NTPCLPEAAVSQP 653
           ++ R+  +   T  + EL  P       + RTP+   P P ++     +A SQP
Sbjct: 160 KERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQP 213


>gi|153792351 ADAM metallopeptidase with thrombospondin type 1
           motif, 8 preproprotein [Homo sapiens]
          Length = 889

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 21/143 (14%)

Query: 444 QPAGDGASEAGTSLV----PATAEPPAETPAEIVDGGVPQAQLAGSDSDLDSDDEFVPYD 499
           QP G G S A    +    PA A P    P   V+ G  Q Q  G D   DS++E    +
Sbjct: 136 QPQGAGGSLAQPHRLQRWGPAGARPLPRGPEWEVETGEGQRQERG-DHQEDSEEESQEEE 194

Query: 500 MSGDRELK-----SSKAPAYVRDC--VEALTTSE---------DIERWEAALRALEGLVY 543
             G  E       +S+   +V +   VE L  ++         D++     L ++   +Y
Sbjct: 195 AEGASEPPPPLGATSRTKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIY 254

Query: 544 RSPTATREVSVELAKVLLHLEEK 566
           + P+    +++ + KVL+  +EK
Sbjct: 255 KHPSIKNSINLMVVKVLIVEDEK 277


>gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo
           sapiens]
          Length = 492

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 634 QPGSPSPNTPCLPEAAVSQP-GSAVASDWRVVVEERIRSKTQRLSKGGPRQGPAGSP 689
           +PG+P+P  PCLP AAV      A A   R+   E   S   RL +GG    P  +P
Sbjct: 393 RPGAPAPPLPCLPPAAVCHALAGAGAPGGRL---ELGLSPGTRLIRGGGAAVPTAAP 446


>gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo
           sapiens]
          Length = 492

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 634 QPGSPSPNTPCLPEAAVSQP-GSAVASDWRVVVEERIRSKTQRLSKGGPRQGPAGSP 689
           +PG+P+P  PCLP AAV      A A   R+   E   S   RL +GG    P  +P
Sbjct: 393 RPGAPAPPLPCLPPAAVCHALAGAGAPGGRL---ELGLSPGTRLIRGGGAAVPTAAP 446


>gi|170784831 chromosome 1 open reading frame 9 protein isoform 2
           [Homo sapiens]
          Length = 1210

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 41/171 (23%), Positives = 71/171 (41%), Gaps = 16/171 (9%)

Query: 287 NLVVKNKKAQFVMTQKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSS 346
           N  ++N+  QF   QK      +L+ P++++L     +D         V  E +E   SS
Sbjct: 46  NCALENEDVQF---QKKNTESKKLSPPVVETLP---TVDLHEESSNAVVDSETVENISSS 99

Query: 347 SAIRHTPLPQQRHVSKAVLICLAQLGEPELRDSRDELLASMMAGVKCRLDSSL-PPVRRL 405
           S    TP+ +   + K+  I +A+  E E  ++  ++  ++ A       S + PP   +
Sbjct: 100 STSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLV 159

Query: 406 GMIVAEVVSARIHPEGPPLKFQYEEDELSLELLALASPQPAGDGASEAGTS 456
           G  +  V S+  H +G   K ++E           AS Q  GD  S    S
Sbjct: 160 GQHIENVSSS--HGKGKITKSEFESK-------VSASEQGGGDPKSALNAS 201


>gi|109637771 calpastatin isoform l [Homo sapiens]
          Length = 654

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 422 PPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQ 481
           PP+   +  D LS +    + PQ A     E    L  A +E  ++TPA     G P   
Sbjct: 450 PPMSEDFLLDALSEDF---SGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPPRD 505

Query: 482 LAGSDSDLD 490
            + SD DLD
Sbjct: 506 TSQSDKDLD 514


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 422 PPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQ 481
           PP+   +  D LS +    + PQ A     E    L  A +E  ++TPA     G P   
Sbjct: 469 PPMSEDFLLDALSEDF---SGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPPRD 524

Query: 482 LAGSDSDLD 490
            + SD DLD
Sbjct: 525 TSQSDKDLD 533


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 422 PPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQ 481
           PP+   +  D LS +    + PQ A     E    L  A +E  ++TPA     G P   
Sbjct: 463 PPMSEDFLLDALSEDF---SGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPPRD 518

Query: 482 LAGSDSDLD 490
            + SD DLD
Sbjct: 519 TSQSDKDLD 527


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 422 PPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQ 481
           PP+   +  D LS +    + PQ A     E    L  A +E  ++TPA     G P   
Sbjct: 504 PPMSEDFLLDALSEDF---SGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPPRD 559

Query: 482 LAGSDSDLD 490
            + SD DLD
Sbjct: 560 TSQSDKDLD 568


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,664,674
Number of Sequences: 37866
Number of extensions: 1556221
Number of successful extensions: 6263
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 6224
Number of HSP's gapped (non-prelim): 85
length of query: 837
length of database: 18,247,518
effective HSP length: 111
effective length of query: 726
effective length of database: 14,044,392
effective search space: 10196228592
effective search space used: 10196228592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.