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Search of human proteins with 224922812
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
(231 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 436 e-123
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 412 e-115
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 342 2e-94
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 340 5e-94
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 340 6e-94
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 330 8e-91
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 325 3e-89
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 314 5e-86
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 311 2e-85
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 307 6e-84
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 301 4e-82
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 286 8e-78
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 279 2e-75
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 271 3e-73
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 266 8e-72
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 259 2e-69
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 239 1e-63
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 76 2e-14
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 74 1e-13
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 73 2e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 4e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 72 4e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 72 4e-13
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 72 5e-13
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 72 5e-13
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 72 5e-13
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 72 5e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 3e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 69 4e-12
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 436 bits (1122), Expect = e-123
Identities = 231/231 (100%), Positives = 231/231 (100%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE
Sbjct: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK
Sbjct: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
Query: 181 EAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
EAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
Sbjct: 181 EAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 412 bits (1058), Expect = e-115
Identities = 231/284 (81%), Positives = 231/284 (81%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SES-----------------------------------------------------EKAA 67
SES EKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 342 bits (876), Expect = 2e-94
Identities = 195/284 (68%), Positives = 208/284 (73%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SES-----------------------------------------------------EKAA 67
SES EKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAEVAES+ LEEEL+ + LKSL A ++YSTKEDKYEEEIKLLEEKLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSVAKLEKTIDDLE+ + + K + I + LD L ++ +L
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 340 bits (873), Expect = 5e-94
Identities = 185/284 (65%), Positives = 214/284 (75%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SES-----------------------------------------------------EKAA 67
SE+ EKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 340 bits (872), Expect = 6e-94
Identities = 190/282 (67%), Positives = 209/282 (74%), Gaps = 53/282 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+AIKKKMQMLKLDKENAIDRAEQAEADKK AED+CKQ+EEE LQKKLKGTEDE++KY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SE-----------------------------------------------------SEKAA 67
SE +EKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYEEVARKLVILEGELER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYEEEIKLL +KLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
FAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 330 bits (845), Expect = 8e-91
Identities = 181/284 (63%), Positives = 209/284 (73%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SES-----------------------------------------------------EKAA 67
SE+ EKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 325 bits (832), Expect = 3e-89
Identities = 178/284 (62%), Positives = 209/284 (73%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDE---- 56
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 57 -------------------------------------------------VEKYSESEKAA 67
++K E+EKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 314 bits (804), Expect = 5e-86
Identities = 174/284 (61%), Positives = 204/284 (71%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDE---- 56
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 57 -------------------------------------------------VEKYSESEKAA 67
++K E+EKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 311 bits (798), Expect = 2e-85
Identities = 172/284 (60%), Positives = 205/284 (72%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SES-----------------------------------------------------EKAA 67
SE+ EKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 307 bits (786), Expect = 6e-84
Identities = 171/284 (60%), Positives = 204/284 (71%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEA++KQAE+R KQLE+E A+QKKLKGTEDE++KY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SES-----------------------------------------------------EKAA 67
SE+ EKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYEEVARKLVI+EG+LER+E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYEEEIK+L +KLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSVAKLEKTIDDLE+ L + K + I + LD L ++ ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 301 bits (770), Expect = 4e-82
Identities = 168/284 (59%), Positives = 200/284 (70%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SES-----------------------------------------------------EKAA 67
SE+ EKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
FAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 286 bits (733), Expect = 8e-78
Identities = 154/240 (64%), Positives = 189/240 (78%), Gaps = 11/240 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
++A+K+K+Q L+ + A DRA+ + + +R ++ E + AL ++++ E+E++
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
K E+EKAADESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
EEVARKLVILEGELER+EERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYE
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
EEIKLL +KLKEAETRAEFAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 279 bits (713), Expect = 2e-75
Identities = 146/242 (60%), Positives = 193/242 (79%), Gaps = 11/242 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E +L ++++ E+E++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
K E+EKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
EEVARKLVI+EG+LER+EERAE+AESR R+++E++R MDQ LK L A+EE+YS KEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
EEIK+L +KLKEAETRAEFAERSVAKLEKTIDDLE+ L KEE++ + LDQTLL+LN
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 230 NL 231
+
Sbjct: 247 EM 248
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 271 bits (693), Expect = 3e-73
Identities = 144/242 (59%), Positives = 189/242 (78%), Gaps = 11/242 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E +L ++++ E+E++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
K E+EKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
EEVARKLVI+EG+LER+EERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
EEIK+L +KLKEAETRAEFAERSVAKLEKTIDDLE+ L KEE++ + LDQTLL+LN
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 230 NL 231
+
Sbjct: 247 EM 248
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 266 bits (681), Expect = 8e-72
Identities = 143/239 (59%), Positives = 186/239 (77%), Gaps = 11/239 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E +L ++++ E+E++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
K E+EKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
EEVARKLVI+EG+LER+EERAE+AESR R+++E++R MDQ LK L A+EE+YS KEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 228
EEIK+L +KLKEAETRAEFAERSVAKLEKTIDDLEE L S E N + L TL +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 259 bits (661), Expect = 2e-69
Identities = 141/239 (58%), Positives = 182/239 (76%), Gaps = 11/239 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E +L ++++ E+E++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
K E+EKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
EEVARKLVI+EG+LER+EERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 228
EEIK+L +KLKEAETRAEFAERSVAKLEKTIDDLEE L S E N + L TL +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 239 bits (611), Expect = 1e-63
Identities = 134/241 (55%), Positives = 172/241 (71%), Gaps = 17/241 (7%)
Query: 1 MDAIKKKMQMLKLDKENAIDRA--------------EQAEADKKQAEDRCKQLEEEQQAL 46
++A+++K++ L+ + A +RA E AEAD R + +EEE
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 47 QKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD 106
Q++L ++K E+EKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+D
Sbjct: 67 QERLATA---LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 107 RKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKED 166
RKYEEVARKLVI+E +LER+EERAE++E + +LEEEL+T+ LKSL A E+YS KED
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
Query: 167 KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 226
+YEEEIK+L +KLKEAETRAEFAERSV KLEK+IDDLE+ L E+N + L L
Sbjct: 184 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALN 243
Query: 227 E 227
E
Sbjct: 244 E 244
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 76.3 bits (186), Expect = 2e-14
Identities = 51/232 (21%), Positives = 115/232 (49%), Gaps = 23/232 (9%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEK 65
++ + + +KE + R E+ +K E++ ++LEE+ +K ++ EK E EK
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEK----IREQEEKRQEEEK 371
Query: 66 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
++ +R + E + + EEK+ QE +++E + + ++ + K E K+ E E++
Sbjct: 372 IREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429
Query: 126 SEERAEVAESRARQLEEELRTMDQALKS---LMASEEE-----------YSTKEDKYEEE 171
EE+ E + R+ E+++R ++ ++ +M +EE K + EE+
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 172 IKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++ EEK++E E + E + + E+ + + EE + +E+ E + + +
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Score = 71.6 bits (174), Expect = 5e-13
Identities = 45/212 (21%), Positives = 104/212 (49%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
K + Q K +E I E+ + + + + +++ E+++ ++++ + +++ EK E E
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE 417
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE 124
+ E E M+ E + + EEK+ QE +++E + + + +E K+ EG++
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477
Query: 125 RSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAET 184
E + + E + R+ EE++R ++ ++ E + EE++ EEK+ E E
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 185 RAEFAERSVAKLEKTIDDLEETLASAKEENVE 216
+ + E + + E+ + + E L +E+ E
Sbjct: 538 KMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 67.8 bits (164), Expect = 8e-12
Identities = 49/216 (22%), Positives = 110/216 (50%), Gaps = 12/216 (5%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKK-QAEDRCKQLEEEQQALQKKLKGTEDEVEK 59
+ ++ K+Q ++++ +R Q + +K + E++ ++ EE+ Q ++K++ ++ EK
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR---EQEEK 317
Query: 60 YSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVIL 119
E+ E E M+ E + EEK+ E ++ E + I E +++ EE +
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK-----I 372
Query: 120 EGELERSEERAEV--AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
+ +R E+ A++ E + R+ EE++R ++ ++ E K + EEE++ EE
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
K++ E + E+ + + E+ I + EE + +E+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/227 (22%), Positives = 106/227 (46%), Gaps = 16/227 (7%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---- 57
D + K++Q + + ++ E +Q E++ + EE+ Q ++K++ E+++
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315
Query: 58 EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVA---- 113
EK E+ E E M+ E + EEK+ E ++ E + I E +++ EE
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375
Query: 114 RKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKEDKYE 169
K E ++ R EE+ E + R+ EE ++ ++ + + + EEE +E+K
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 216
+ EEK++E E + E + + E+ + + EE + + + E
Sbjct: 436 RQ----EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Score = 67.4 bits (163), Expect = 1e-11
Identities = 48/215 (22%), Positives = 106/215 (49%), Gaps = 16/215 (7%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTE---DEVEKYS 61
+K+ ++ +L+++ + + +K+Q E++ ++ E+ Q+ K + E ++ EK
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
E E+ E E M E + + EE+M+ QE +++ + + ++K E K+ E
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL---EEK 178
++ EE+ + E + E+E + +Q EE+ +E+K E+ K + EEK
Sbjct: 461 MMQEQEEK--MGEQEGKMCEQEAKMQEQ--------EEKMRRQEEKIREQEKKIREQEEK 510
Query: 179 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
++E E + E + + E+ + + EE + +E+
Sbjct: 511 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Score = 58.9 bits (141), Expect = 4e-09
Identities = 35/182 (19%), Positives = 94/182 (51%), Gaps = 11/182 (6%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ I+++ +M++ +E ++ E+ +++ +++ +++ +++ ++++ K ++ EK
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
E E+ E E M E + + E KM+ QE +++ + + ++K E K+ E
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL--EEKL 179
++ EE+ E + + EE+++ ++ ++ +E E+E++L EEK+
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR---------QEEKMREQEVRLRQQEEKM 567
Query: 180 KE 181
+E
Sbjct: 568 QE 569
Score = 48.9 bits (115), Expect = 4e-06
Identities = 46/201 (22%), Positives = 91/201 (45%), Gaps = 26/201 (12%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVI----ENRAMKDEEKMELQE 92
++L+E+ LQ+KL+ E E + + K K++ + +A D ELQ
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 93 MQLKEAKHIAEDS--DRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQA 150
+ K + E+ +R ++ K+ E +++ EE+ + E + R+ EE++R ++
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 151 L-----------KSLMASEEEYSTKEDKYEEEIKLL--------EEKLKEAETRAEFAER 191
+ + + EE+ E+K E+ K+ EEK++E E R E E
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE-QEA 383
Query: 192 SVAKLEKTIDDLEETLASAKE 212
+ + E+ I + EE + +E
Sbjct: 384 KMWRQEEKIREQEEKIREQEE 404
Score = 46.2 bits (108), Expect = 2e-05
Identities = 52/214 (24%), Positives = 102/214 (47%), Gaps = 32/214 (14%)
Query: 19 IDRAEQAEADKKQAEDR-CKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVI 77
+++A A A +K+ DR ++L +E+ AL +E Y + + E+ K+
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALS---------LELYRNTITDEELKEKNAKLQ 215
Query: 78 ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS------EERAE 131
E + + EK E+Q + +KE K RK E KL++ + +L+ E ++
Sbjct: 216 EKLQLVESEKSEIQ-LNVKELK-------RKLERA--KLLLPQQQLQAEADHLGKELQSV 265
Query: 132 VAESRARQLEEEL--RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFA 189
A+ +A+ E EL R Q + + EE+ +E+K +E+ EEK++E E +
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ----EEKIREQEEKMRRQ 321
Query: 190 ERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
E + + E+ + EE + +E+ E+ + + +
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 73.9 bits (180), Expect = 1e-13
Identities = 63/225 (28%), Positives = 106/225 (47%), Gaps = 17/225 (7%)
Query: 9 QMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAAD 68
QML L +R + E ++ E+R ++ EE +++L+ E E+ E E+
Sbjct: 188 QMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQE---ERLREQEERLC 244
Query: 69 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 128
E E ++ E R + EE++ QE +L+E + + E +L E L EE
Sbjct: 245 EQEERLREHEERLCEQEERLCEQEERLRE-------QEERLHEQEERLCEQEERLREQEE 297
Query: 129 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE--KLKEAETRA 186
R E R R+ EE L ++ L+ +EE +++K + +LLEE KL E E R
Sbjct: 298 RLCEQEERLREQEERLCEQEERLRE----QEERLCEQEKLPGQERLLEEVEKLLEQERRQ 353
Query: 187 EFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
E ER + + E+ ++++EE L + + +TL EL L
Sbjct: 354 EEQERLLER-ERLLEEVEELLEQERLRQQDERLWQQETLQELERL 397
Score = 60.8 bits (146), Expect = 9e-10
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 7/202 (3%)
Query: 29 KKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDEEKM 88
+K+ E +QL+ E + Q + E+ E E+ E E ++ E R + EE++
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERL 229
Query: 89 ELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMD 148
QE +L+E + + + + E +L E L EER E R + EE L +
Sbjct: 230 REQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQE 289
Query: 149 QALKSLMASEEEYSTKEDKYEEEIKLL---EEKLKEAETRAEFAERSVAKLEKTIDDLEE 205
+ L+ EE +E++ E+ + L EE+L+E E R E+ + E+ ++++E+
Sbjct: 290 ERLRE---QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEK 345
Query: 206 TLASAKEENVEIHQTLDQTLLE 227
L + + + + LLE
Sbjct: 346 LLEQERRQEEQERLLERERLLE 367
Score = 58.5 bits (140), Expect = 5e-09
Identities = 54/221 (24%), Positives = 99/221 (44%), Gaps = 15/221 (6%)
Query: 10 MLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAAD- 68
+ KL + A A + A + E QL++E L+K+L+ +++ E+ +
Sbjct: 137 LFKLKNQTAEPLAPEPPAGPSKVE----QLQDETNHLRKELESVGRQLQAEVENNQMLSL 192
Query: 69 ---ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
E ++ E R + EE++ QE +L E + + + + E +L E L
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 126 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL---EEKLKEA 182
EER E R + EE LR ++ L EE +E++ E+ + L EE+L+E
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHE---QEERLCEQEERLREQEERLCEQEERLREQ 309
Query: 183 ETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
E R E + + E+ + + +E L + E+ + L+Q
Sbjct: 310 EERLCEQEERLREQEERLCE-QEKLPGQERLLEEVEKLLEQ 349
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 73.2 bits (178), Expect = 2e-13
Identities = 65/226 (28%), Positives = 111/226 (49%), Gaps = 21/226 (9%)
Query: 2 DAIKKKMQMLKLDKENA-IDRAE---------QAEADKKQAEDRCKQLEEEQQALQKKLK 51
D I +M + DKE A +RA +AE DKK A++R + EE+ A Q++ +
Sbjct: 249 DEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 52 GTEDEVEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEE 111
+E E+ E EK A E + +K E RA ++ ++++ +E K AE+ R EE
Sbjct: 309 REAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIK------EEEKRAAEERQRIKEE 362
Query: 112 VARKLVILEGELERSEERAEVAE-SRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 170
R + EE+A+V E R +QLEE+ M + + + E+ E K+
Sbjct: 363 EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE---TKIKGEKVEQKIEGKWVN 419
Query: 171 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 216
E K E+KL+ A + + E+ K++ + L+E + K+E ++
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKG-TKVQAKREKLQEDKPTFKKEEIK 464
Score = 60.5 bits (145), Expect = 1e-09
Identities = 49/189 (25%), Positives = 100/189 (52%), Gaps = 15/189 (7%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV------E 58
++K + ++ A +R E +K+ AE+R + EEE++A +++ + E+E +
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Query: 59 KYSESEK-AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV 117
+ E EK AA+E +R E +A +E+K + QL+E KH +++ K E+V +K
Sbjct: 358 RIKEEEKRAAEERQRARAEEEEKAKVEEQK---RNKQLEEKKHAMQETKIKGEKVEQK-- 412
Query: 118 ILEGEL--ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL 175
+EG+ E+ + ++ + ++ EE T QA + + ++ KE+ +E+IK
Sbjct: 413 -IEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
Query: 176 EEKLKEAET 184
+E +E ++
Sbjct: 472 KEPKEEVKS 480
Score = 55.5 bits (132), Expect = 4e-08
Identities = 50/241 (20%), Positives = 110/241 (45%), Gaps = 19/241 (7%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGT--EDEVEKYSE 62
+ + + ++++ + ++ Q + E++ + E+E++ +K +G+ E++VE E
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE 213
Query: 63 SEKAADESERGMKVIENRAM-----KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV 117
+ + E + ++N + K EE+ E ++ + + E+ + E +L
Sbjct: 214 EKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---------Y 168
E E ++E+ ++A+ RAR +E E + Q + A E E +E+K
Sbjct: 274 AEERERIKAEQDKKIADERAR-IEAEEKAAAQERERREAEERERMREEEKRAAEERQRIK 332
Query: 169 EEEIKLLEE--KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 226
EEE + EE ++KE E RA + + + EK + + + +EE ++ + L
Sbjct: 333 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392
Query: 227 E 227
E
Sbjct: 393 E 393
Score = 55.5 bits (132), Expect = 4e-08
Identities = 50/192 (26%), Positives = 88/192 (45%), Gaps = 27/192 (14%)
Query: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESE 71
K ++E E + +K + ED+ E +A + +L+ E E K + +K ADE
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDK-----ERAEAERARLEAEERERIKAEQDKKIADERA 293
Query: 72 RGMKVIENRAMKDEEKMELQEMQLKEA---KHIAEDSDRKYEEVARKLVILEGELERSEE 128
R ++ EEK QE + +EA + + E+ R EE R I E E +EE
Sbjct: 294 R---------IEAEEKAAAQERERREAEERERMREEEKRAAEERQR---IKEEEKRAAEE 341
Query: 129 RAEV-------AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKE 181
R + AE R R EEE R ++ ++ EE+ +E K ++++ + ++E
Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401
Query: 182 AETRAEFAERSV 193
+ + E E+ +
Sbjct: 402 TKIKGEKVEQKI 413
Score = 52.8 bits (125), Expect = 3e-07
Identities = 58/241 (24%), Positives = 102/241 (42%), Gaps = 49/241 (20%)
Query: 26 EADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---EKYSESE------------------ 64
+A++ + ED+ K+ EEE++ + + + EV EK +ES+
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 65 KAADESERGMKVIENRAMKDEEKMELQE-----MQLKEAKHIAEDSDRKYE------EVA 113
K +E E+G I + +EE E E ++ +E + I + D+K E
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAE 298
Query: 114 RKLVILEGELERSEERAEV-------AESRARQLEEELRTMDQALKSLMASEEEYSTKED 166
K E E +EER + AE R R EEE R ++ + EEE E+
Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQR---IKEEEKRAAEE 355
Query: 167 KYEEEIKLLEEKLKEAETRAEFAERSVAKLE-----KTIDDLEETLASAKEENVEIHQTL 221
+ + IK E++ E RA E AK+E K +++ + + K + ++ Q +
Sbjct: 356 R--QRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKI 413
Query: 222 D 222
+
Sbjct: 414 E 414
Score = 40.0 bits (92), Expect = 0.002
Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 28/191 (14%)
Query: 22 AEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRA 81
A Q EA K+ E R ++ E E + +K K + E A + E K E R
Sbjct: 527 APQVEAGKRLEELRRRRGETESEEFEKL---------KQKQQEAALELEELKKKREERRK 577
Query: 82 MKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLE 141
+ +EE E + E++DRK E K + E E+ER RAE AE R + E
Sbjct: 578 VLEEE----------EQRRKQEEADRKLREEEEKRRLKE-EIER--RRAEAAEKRQKMPE 624
Query: 142 EELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKL-KEAETRAEFAERSVAKLEKTI 200
+ L + K K EE + L + + K + ++ V+K++ +
Sbjct: 625 DGLSDDKKPFKCFTPKGSSL-----KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRL 679
Query: 201 DDLEETLASAK 211
+ + K
Sbjct: 680 EQYTSAIEGTK 690
Score = 35.8 bits (81), Expect = 0.032
Identities = 44/232 (18%), Positives = 87/232 (37%), Gaps = 33/232 (14%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MD +++ ++ + +E AE+ + + EE+ A +++ + ++ + +
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDD-------EEEAARERRRRARQERLRQK 53
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
E E +++ ++V ++ DEE E A +R R+ L+
Sbjct: 54 QEEESLGQVTDQ-VEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 112
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE----------- 169
LER +E + L D A EE+ +++++YE
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172
Query: 170 ------------EEIKLLEEKLKEAETRAEFAERSVAKL--EKTIDDLEETL 207
+E K EE+ +E R E V + EKT + EET+
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETV 224
Score = 33.5 bits (75), Expect = 0.16
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 20/149 (13%)
Query: 15 KENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGM 74
K+ + A + E KK+ E+R K LEEE+Q ++K + + ++ + E + +E ER
Sbjct: 555 KQKQQEAALELEELKKKREERRKVLEEEEQ--RRKQEEADRKLREEEEKRRLKEEIER-- 610
Query: 75 KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAE 134
RA E++ ++ E L + K K +G + EERAE
Sbjct: 611 ----RRAEAAEKRQKMPEDGLSDDKK------------PFKCFTPKGSSLKIEERAEFLN 654
Query: 135 SRARQLEEELRTMDQALKSLMASEEEYST 163
++ T A+ S + S E T
Sbjct: 655 KSVQKSSGVKSTHQAAIVSKIDSRLEQYT 683
Score = 29.6 bits (65), Expect = 2.3
Identities = 25/117 (21%), Positives = 51/117 (43%), Gaps = 6/117 (5%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKK-QAEDRCKQLEEE-----QQALQKKLKGTE 54
++ +KKK + + E R +Q EAD+K + E+ ++L+EE +A +K+ K E
Sbjct: 565 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Query: 55 DEVEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEE 111
D + + K +K+ E ++ + ++ I D + E+
Sbjct: 625 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQ 681
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 72.0 bits (175), Expect = 4e-13
Identities = 50/229 (21%), Positives = 114/229 (49%), Gaps = 12/229 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTED---EVEKYS 61
K+KM + ++ + E ++ E++ ++ EE+ ++K++ E+ E EK
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
E EK +E +R + E++ + EEK+ QE ++ + + + K +E K+ E
Sbjct: 555 EQEKIWEEEKRQEQ--EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 122 ELERSEERAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKEDKYEEEIKLL-- 175
++ EE+ + E + R+ EE++R ++ + + EE+ +E+K +E+ + +
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 176 -EEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
EEK++E E + E + + E+ + + EE + +E+ E + + +
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Score = 67.0 bits (162), Expect = 1e-11
Identities = 55/219 (25%), Positives = 105/219 (47%), Gaps = 14/219 (6%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
D + K++Q + + ++ E +Q E++ + EE+ Q ++K+ +++ EK
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI---QEQEEKIR 324
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
E E+ E E M+ E + EEKM QE + E E+ R+ EE+ + E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK----EEKMRRQEEMMWEK---EE 377
Query: 122 ELERSEERAEVAESRARQLEEELRTMD--QALKSLMASEEEYSTKEDKYEEEIKL--LEE 177
++ R EE E + R+LEE++ + + + EE+ +E + E+E K+ EE
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 216
K++E E + E+ + + E+ I + E+ K + E
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Score = 67.0 bits (162), Expect = 1e-11
Identities = 44/210 (20%), Positives = 105/210 (50%), Gaps = 4/210 (1%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---- 57
+ I+++ +M + +++ E +++ ED+ + EE+ + ++K+ E+++
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 58 EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV 117
EK E E+ + E ++ E + + EEK+ QE +++E + + ++ + K E K+
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
E +++ EE E + R+ E+++R ++ ++ +E K + EE++ EE
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETL 207
K++E E + E + + E + EE +
Sbjct: 718 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Score = 64.7 bits (156), Expect = 6e-11
Identities = 51/220 (23%), Positives = 106/220 (48%), Gaps = 13/220 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTE---DEVEKYS 61
+K+ ++ +L+++ + + +K+Q E++ ++ E+ Q+ K + E ++ EK
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-----RKYEEVARKL 116
E EK E K+ E +++EEK + QE ++ + I E + K E K+
Sbjct: 448 EQEKKMWRQEE--KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 117 VILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE 176
E ++ R EE+ E + R+ EE++ ++ ++ EE + +E +E+E E
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE---QEEMWREEEKMHEQEKIWEE 562
Query: 177 EKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 216
EK +E E + E + + E+ + EE + +E+ E
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602
Score = 63.9 bits (154), Expect = 1e-10
Identities = 48/226 (21%), Positives = 105/226 (46%), Gaps = 4/226 (1%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---- 57
+ I+++ + ++ +E + E+ ++ + K E+E+ ++K + ED++
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 58 EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV 117
EK E E+ E ++ E + + EEKM QE +++E + ++ + K E K+
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
E + EE+ E + + EE+++ ++ + E K + EE+I+ EE
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++E E + E + + E+ + + EE + +E+ E L Q
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Score = 62.0 bits (149), Expect = 4e-10
Identities = 48/233 (20%), Positives = 113/233 (48%), Gaps = 21/233 (9%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEE---EQQALQKKLKGTEDEVE 58
+ I+++ + + +E ++ + E +K+Q ++ + EE EQ+ + ++ + ++ E
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 59 KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE-------- 110
K + E+ E ++ E + + EEKM QE +++E + + + ++ +E
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 111 ---EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL----KSLMASEEEYST 163
E K+ E ++ EE+ E + R+ EE+ + ++ + + + EE+
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
Query: 164 KEDKY---EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+E+K EE+I+ EE +E E + E + + E+ + + EET+ +E+
Sbjct: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Score = 61.6 bits (148), Expect = 5e-10
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 18/230 (7%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---- 57
+ ++++ +M+ +E + E+ +K E K+ EEE+ Q+K + E ++
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 58 EKYSESEKAADESERGM-----KVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-----R 107
EK E E+ E E+ M K+ E +++EEK + QE ++ + I E +
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 108 KYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSL--MASEEEYSTKE 165
K E K+ E ++ R EE+ E + R+ EE++ ++ ++ M EEE ++
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Query: 166 DKYEEEIKL--LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+K EE K E+K+ E + E V + E+ I + EE +E+
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Score = 61.6 bits (148), Expect = 5e-10
Identities = 43/235 (18%), Positives = 112/235 (47%), Gaps = 20/235 (8%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV-------- 57
++ + ++ +E ++ ++ +++ ++ K EEE++ Q+++ E+++
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 58 ---------EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRK 108
EK + E+ E ++ E + + EEKM QE +++E + + + ++
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553
Query: 109 YEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY 168
+E+ + + E + + E++ E + R+ EE++ ++ ++ +E K K
Sbjct: 554 HEQ---EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 169 EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
EE+I+ EEK++E E + E + + E+ + EE + +E+ E + + +
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Score = 60.1 bits (144), Expect = 2e-09
Identities = 53/213 (24%), Positives = 104/213 (48%), Gaps = 20/213 (9%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---EKYSESEKAADESE---RG 73
++ ++ EA + E++ ++ EE+ + +KK+ E+++ EK E EK ++ E +
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482
Query: 74 MKVIENRAM-KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 132
K+ E + + +EKM QE ++++ + + K E K+ E ++ R EE+
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE 542
Query: 133 AESRARQLE---------EELRTMDQALKSLMASEEEYSTKEDKY---EEEIKLLEEKLK 180
E R+ E EE + +Q K + EE+ +E+K EE+I+ EEK +
Sbjct: 543 QEEMWREEEKMHEQEKIWEEEKRQEQEDK-MWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 181 EAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
E E + E + + E+ I + EE + +E+
Sbjct: 602 EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Score = 58.5 bits (140), Expect = 5e-09
Identities = 41/164 (25%), Positives = 81/164 (49%), Gaps = 14/164 (8%)
Query: 23 EQAEADKKQAEDRCKQLE---EEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIEN 79
EQ E ++Q E KQ E E+++ +Q++ + ++ EK E E+ E E M E
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 654
Query: 80 RAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQ 139
+ + EEKM+ QE + + + ++K E K+ E ++ EE+ E + +
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
Query: 140 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKE 181
EE+++ ++ ++ +E +E+E++L EEK++E
Sbjct: 715 QEEKMQEQEEKMRR---------QEEKMWEQEVRLRQQEEKMQE 749
Score = 56.2 bits (134), Expect = 2e-08
Identities = 30/160 (18%), Positives = 83/160 (51%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ I+++ + + +E + E+ +++ +++ +++ E+++ ++++ + T+++ EK
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
E E+ E E M+ E + EEK+ QE +++E + + + +E K+ E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEY 161
++ EE+ + E + R+ EE++ + L+ +E+
Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 55.1 bits (131), Expect = 5e-08
Identities = 50/228 (21%), Positives = 113/228 (49%), Gaps = 16/228 (7%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ + + ++RA+ ++Q + L +E Q++ KL+ +E E +
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 61 SESEKAADES----ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD----RKYEEV 112
+ + +E E ++ E + + EEK+ QE +++E + + K E++
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 113 ARKLVIL---EGELERSEERAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTKED 166
R+ ++ E ++ R EE E + R+ EE + ++ ++ L M +E+ +E+
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 167 KYEEEIKLLE-EKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
K +EE K+ E EK +E E + E + + E+ I + E+ + +E+
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Score = 52.4 bits (124), Expect = 3e-07
Identities = 47/215 (21%), Positives = 102/215 (47%), Gaps = 15/215 (6%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKY 60
++K+Q + + ++ + E ++ E++ ++ EE ++K++ E+ + EK
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
E+ E E M+ E + EEK+ E ++ E + I E +++ EE +
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK-----IR 420
Query: 121 GELERSEERAEV--AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEK 178
+ +R E+ A++ E + R+ EE++R + K + EE+ +E EEE + +E+
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQE---KKMWRQEEKIHEQEKIREEEKRQEQEE 477
Query: 179 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+ E + E + EK + + EE + +E+
Sbjct: 478 MWRQEEKIHEQEEIWRQKEK-MHEQEEKIRKQEEK 511
Score = 51.2 bits (121), Expect = 7e-07
Identities = 41/219 (18%), Positives = 101/219 (46%), Gaps = 7/219 (3%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ I+++ + ++ +E ++ E+ ++ ++ +++ +++ + +K + + E
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 62 ESEKAADESERGMKVIENRAMKDEEKM----ELQEMQLKEAKHIAEDSDRKYEEVARKLV 117
E E+ E M E + + EEKM +++E + K + K +E K+
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEIKL 174
E ++ EE+ E + + EE++ ++ + E+E ++++ +EEI
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 175 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+EK+ E E + E V + E+ I + EE + +E+
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 50.4 bits (119), Expect = 1e-06
Identities = 42/184 (22%), Positives = 90/184 (48%), Gaps = 13/184 (7%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVI----ENRAMKDEEKMELQE 92
++L+E+ LQ+KL+ E E + + K K++ + +A D ELQ
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 93 MQLKEAKHIAEDS--DRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQA 150
+ K + E+ +R ++ K+ E +++ EE+ + E + R+ EE++R ++
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 151 LK---SLMASEEEYSTKEDKY----EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 203
++ +M +EE ++++ EE+++ EE + E E + E + + E+ I +L
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 204 EETL 207
EE +
Sbjct: 397 EEKM 400
Score = 48.1 bits (113), Expect = 6e-06
Identities = 47/195 (24%), Positives = 94/195 (48%), Gaps = 30/195 (15%)
Query: 19 IDRAEQAEADKKQAEDR-CKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVI 77
+++A A A +K+ DR ++L +E+ AL +E Y + + E+ K+
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALS---------LELYRNTITDEELKEKNAKLQ 227
Query: 78 ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRA 137
E + + EK E+Q + +KE K RK E KL++ + +L+ + A
Sbjct: 228 EKLQLVESEKSEIQ-LNVKELK-------RKLERA--KLLLPQQQLQ----------AEA 267
Query: 138 RQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLE 197
L +EL+++ L++ + E ++ + EE++ EEK++E E + + E + + E
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 198 KTIDDLEETLASAKE 212
+ I + EE + +E
Sbjct: 328 EKIREQEEKMRRQEE 342
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 72.0 bits (175), Expect = 4e-13
Identities = 55/206 (26%), Positives = 104/206 (50%), Gaps = 22/206 (10%)
Query: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKYSESEKAADES----ERGM 74
EQ E ++Q E +Q EE+ + +K++ E+E+ EK E E+ E E+ M
Sbjct: 357 EQEEKIREQEEKMWRQ-EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 75 KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAE 134
+ + + + EE+M QE +++E + + +D + K EV K+ E +++ EE+ + E
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475
Query: 135 SRARQLEEELRTMDQALK---SLMASEEEYSTKEDK----------YEEEIKLLEEKLKE 181
+ ++ EE+ ++ LK + EE+ +E+K EE+++ EEK++E
Sbjct: 476 EKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535
Query: 182 AETRAEFAERSVAKLEKTIDDLEETL 207
E R E + + E + +LEE L
Sbjct: 536 QEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 70.9 bits (172), Expect = 9e-13
Identities = 56/231 (24%), Positives = 113/231 (48%), Gaps = 10/231 (4%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRC-----KQLEEEQQALQKKLKGTEDE 56
D + K++Q + + ++ E +Q E++ K E+E++ +++LK E E
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 57 VEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKL 116
+ + + EK ++ E+ ++ E++ + EEK+ QE +++E + + K E K+
Sbjct: 325 EKMWRQEEKMHEQEEK-IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 117 VILEGELERSEERA-EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEI 172
E E+ R EE+ E E R ++ + + M + + + EEE +E+K EE +
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
Query: 173 KLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
+ EEKL+E E + + E + + E+ I EE + +E+ + L Q
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 70.1 bits (170), Expect = 2e-12
Identities = 56/240 (23%), Positives = 113/240 (47%), Gaps = 20/240 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAE--------QAEADKK----QAEDRCKQLEEEQQALQK 48
+++ K ++Q+ D + ++RA+ Q EAD+ Q+ Q + E+ L
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN 289
Query: 49 KLKGTEDEV-----EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
L ++E EK E E+ E E ++ E + + EEKM QE +++E +
Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYST 163
+ K E K+ E ++ R EE+ + + ++ EEE+ ++ ++ EE+
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE---QEEKRQE 406
Query: 164 KEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
K + E++++ +EK++E E E + +LE+ + D EE L +E+ E + + +
Sbjct: 407 KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Score = 68.9 bits (167), Expect = 3e-12
Identities = 49/208 (23%), Positives = 108/208 (51%), Gaps = 9/208 (4%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKYSESEKAADESERGMKVIEN 79
+ E ++ E++ + EE+ ++K++ ED++ EK E E+ E E M E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 80 RAMKDEEKMELQEMQL-KEAKHIAEDSDRKYEEVAR---KLVILEGELERSEERAEVAES 135
+ + +EK++ QE ++ ++ + I E +++ E++ R K+ + ++ EE E
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 136 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAK 195
+ R+LEE ++ ++ L+ + +E K + EE+I+ EEK++E E + + + + K
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT-WRQEKLLK 493
Query: 196 LEKTIDDLEETLASAKEENVEIHQTLDQ 223
E+ I + EE + +E+ E + + +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Score = 60.1 bits (144), Expect = 2e-09
Identities = 47/197 (23%), Positives = 98/197 (49%), Gaps = 6/197 (3%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKYSESEKAADESERGMK 75
++ + E + E++ +++EE+ Q ++K++ E+++ EK E E+ E+ +K
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 76 VIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAES 135
E + + EEKM QE ++ E + ++ + K + K+ E L + EE+ + E
Sbjct: 494 Q-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Query: 136 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAK 195
R ++LEE L + Q + L + E ++ I +E K +EA++ + +
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGH 612
Query: 196 LEKTIDDLEETLASAKE 212
L++ + ++ LAS KE
Sbjct: 613 LQQYVAAYQQ-LASGKE 628
Score = 58.9 bits (141), Expect = 4e-09
Identities = 46/187 (24%), Positives = 93/187 (49%), Gaps = 24/187 (12%)
Query: 5 KKKMQMLKLDKE--NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
K++ +M + +K+ ++ + E + + E++ ++LEE Q ++KL+ E EK E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE---EKMQE 459
Query: 63 SEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
E+ E E ++ E + + EEK QE LK+ + I E ++ + + E +
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ--------EEK 511
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLK 180
+ EE+ + E + ++ EE++R + L + +E E+E++L LEE+L
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRL---------WQQEEKMQEQEVRLQELEERLG 562
Query: 181 EAETRAE 187
+ +AE
Sbjct: 563 KLGQKAE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 72.0 bits (175), Expect = 4e-13
Identities = 55/206 (26%), Positives = 104/206 (50%), Gaps = 22/206 (10%)
Query: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKYSESEKAADES----ERGM 74
EQ E ++Q E +Q EE+ + +K++ E+E+ EK E E+ E E+ M
Sbjct: 357 EQEEKIREQEEKMWRQ-EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 75 KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAE 134
+ + + + EE+M QE +++E + + +D + K EV K+ E +++ EE+ + E
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475
Query: 135 SRARQLEEELRTMDQALK---SLMASEEEYSTKEDK----------YEEEIKLLEEKLKE 181
+ ++ EE+ ++ LK + EE+ +E+K EE+++ EEK++E
Sbjct: 476 EKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535
Query: 182 AETRAEFAERSVAKLEKTIDDLEETL 207
E R E + + E + +LEE L
Sbjct: 536 QEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 70.9 bits (172), Expect = 9e-13
Identities = 56/231 (24%), Positives = 113/231 (48%), Gaps = 10/231 (4%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRC-----KQLEEEQQALQKKLKGTEDE 56
D + K++Q + + ++ E +Q E++ K E+E++ +++LK E E
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 57 VEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKL 116
+ + + EK ++ E+ ++ E++ + EEK+ QE +++E + + K E K+
Sbjct: 325 EKMWRQEEKMHEQEEK-IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 117 VILEGELERSEERA-EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEI 172
E E+ R EE+ E E R ++ + + M + + + EEE +E+K EE +
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
Query: 173 KLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
+ EEKL+E E + + E + + E+ I EE + +E+ + L Q
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 70.1 bits (170), Expect = 2e-12
Identities = 56/240 (23%), Positives = 113/240 (47%), Gaps = 20/240 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAE--------QAEADKK----QAEDRCKQLEEEQQALQK 48
+++ K ++Q+ D + ++RA+ Q EAD+ Q+ Q + E+ L
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN 289
Query: 49 KLKGTEDEV-----EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
L ++E EK E E+ E E ++ E + + EEKM QE +++E +
Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYST 163
+ K E K+ E ++ R EE+ + + ++ EEE+ ++ ++ EE+
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE---QEEKRQE 406
Query: 164 KEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
K + E++++ +EK++E E E + +LE+ + D EE L +E+ E + + +
Sbjct: 407 KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Score = 68.9 bits (167), Expect = 3e-12
Identities = 49/208 (23%), Positives = 108/208 (51%), Gaps = 9/208 (4%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKYSESEKAADESERGMKVIEN 79
+ E ++ E++ + EE+ ++K++ ED++ EK E E+ E E M E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 80 RAMKDEEKMELQEMQL-KEAKHIAEDSDRKYEEVAR---KLVILEGELERSEERAEVAES 135
+ + +EK++ QE ++ ++ + I E +++ E++ R K+ + ++ EE E
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 136 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAK 195
+ R+LEE ++ ++ L+ + +E K + EE+I+ EEK++E E + + + + K
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT-WRQEKLLK 493
Query: 196 LEKTIDDLEETLASAKEENVEIHQTLDQ 223
E+ I + EE + +E+ E + + +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Score = 60.1 bits (144), Expect = 2e-09
Identities = 47/197 (23%), Positives = 98/197 (49%), Gaps = 6/197 (3%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV----EKYSESEKAADESERGMK 75
++ + E + E++ +++EE+ Q ++K++ E+++ EK E E+ E+ +K
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 76 VIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAES 135
E + + EEKM QE ++ E + ++ + K + K+ E L + EE+ + E
Sbjct: 494 Q-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Query: 136 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAK 195
R ++LEE L + Q + L + E ++ I +E K +EA++ + +
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGH 612
Query: 196 LEKTIDDLEETLASAKE 212
L++ + ++ LAS KE
Sbjct: 613 LQQYVAAYQQ-LASGKE 628
Score = 58.9 bits (141), Expect = 4e-09
Identities = 46/187 (24%), Positives = 93/187 (49%), Gaps = 24/187 (12%)
Query: 5 KKKMQMLKLDKE--NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
K++ +M + +K+ ++ + E + + E++ ++LEE Q ++KL+ E EK E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE---EKMQE 459
Query: 63 SEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
E+ E E ++ E + + EEK QE LK+ + I E ++ + + E +
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ--------EEK 511
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLK 180
+ EE+ + E + ++ EE++R + L + +E E+E++L LEE+L
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRL---------WQQEEKMQEQEVRLQELEERLG 562
Query: 181 EAETRAE 187
+ +AE
Sbjct: 563 KLGQKAE 569
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 71.6 bits (174), Expect = 5e-13
Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 24/245 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
+++MQ + + + +R ++AE + K+ E + QL EE+ LQ++L+ E E Y+E+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 65 K-----AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE----DSDRKYEEVARK 115
+ AA + E + E A +EE+ Q++Q + K + + + EE AR+
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 116 LVILE-----GELERSEERAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTK--- 164
+ LE ++++ E+ V + + +L +E + +++ + L +A EEE +
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 165 -EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++K+E I LE +LK+ E + E+ KLE D E +A + + E+ L +
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 224 TLLEL 228
EL
Sbjct: 1088 KEEEL 1092
Score = 60.8 bits (146), Expect = 9e-10
Identities = 43/189 (22%), Positives = 92/189 (48%), Gaps = 15/189 (7%)
Query: 28 DKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDE-- 85
+K++ E R QLEEE + Q ++ D V K ++ A++ + + A K+E
Sbjct: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ---AEQLSNELATERSTAQKNESA 1786
Query: 86 -EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
+++E Q +L+ H E + + + + LE ++ + EE+ E + + L
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKS--KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1844
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEE-------IKLLEEKLKEAETRAEFAERSVAKLE 197
+ D+ LK ++ E+ ++Y+E+ +K L+ +L+EAE ++ + KL+
Sbjct: 1845 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1904
Query: 198 KTIDDLEET 206
+ +D+ E+
Sbjct: 1905 RELDEATES 1913
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/238 (23%), Positives = 117/238 (49%), Gaps = 21/238 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY---- 60
+KK + L+ D + AE +KQA+ ++L EE + +DE +
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-------RKYEEVA 113
++ E+ +E + M+ + +R K ++ E +L + A+ ++ R+ +E+
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Query: 114 RKLVILEGELERSEERAEVA--ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE 171
KL +EG + +S+ ++ +A E++ QLEE++ +Q + A+ + K+ K +E
Sbjct: 1799 SKLHEMEGAV-KSKFKSTIAALEAKIAQLEEQV---EQEAREKQAATKSLKQKDKKLKEI 1854
Query: 172 IKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
+ +E++ K AE E AE+ A++++ LEE A+EE+ I+ + EL+
Sbjct: 1855 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEE----AEEESQRINANRRKLQRELD 1908
Score = 58.5 bits (140), Expect = 5e-09
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Query: 16 ENAIDRAEQAEADKK----QAEDRCKQLEEEQQALQK----------KLKGTEDEV---- 57
E DR +Q +A++K Q D +QLEEE+ A QK K+K EDE+
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 58 ---EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR 114
K S+ K +E R + N A ++E+ L +++ K I+E
Sbjct: 992 DQNNKLSKERKLLEE--RISDLTTNLAEEEEKAKNLTKLKNKHESMISE----------- 1038
Query: 115 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 174
LE L++ E+ + E R+LE + + + L A E + K EEE++
Sbjct: 1039 ----LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094
Query: 175 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 211
+L + + A + + +LE I DL+E L S +
Sbjct: 1095 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131
Score = 53.9 bits (128), Expect = 1e-07
Identities = 56/267 (20%), Positives = 107/267 (40%), Gaps = 42/267 (15%)
Query: 7 KMQMLKLDKE--NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KMQ+ K ++E A+ R + A K A + ++LE LQ+ L K + +
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 65 KAADESERGMKVI------------ENRAMKDEE---------------KMELQEMQLKE 97
+ E +K E RA +++E + ++QEM+ K
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 98 AKHIAE-------------DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
A+ + E + D+ + + ++ L GEL + + E + ++LE ++
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 204
+ + + E + K K + E++ + L EAE +A + VA L + D +
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1321
Query: 205 ETLASAKEENVEIHQTLDQTLLELNNL 231
E L + + + L Q E N+L
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEEERNSL 1348
Score = 51.6 bits (122), Expect = 6e-07
Identities = 49/202 (24%), Positives = 93/202 (46%), Gaps = 11/202 (5%)
Query: 13 LDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESER 72
LD+E A+ E +K A+ ++L E+ + K+ K D+ ++ E E A E
Sbjct: 1183 LDEETRSHEAQVQEMRQKHAQ-AVEELTEQLEQF-KRAKANLDKNKQTLEKENADLAGE- 1239
Query: 73 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 132
++V+ + E K + E Q++E + D +R E+ K+ L+ E+E
Sbjct: 1240 -LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 133 AESRARQLEEELRTMDQALKSLMASEEE-------YSTKEDKYEEEIKLLEEKLKEAETR 185
AE +A +L +++ ++ L+ +E STK + EEE L+++L E
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
Query: 186 AEFAERSVAKLEKTIDDLEETL 207
+ ER ++ L + D ++ L
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKL 1380
Score = 51.2 bits (121), Expect = 7e-07
Identities = 58/264 (21%), Positives = 112/264 (42%), Gaps = 36/264 (13%)
Query: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAE---------------DRCKQLEEEQQALQ 47
A++ +M+ +K E D + E K + E R +Q EE+++ LQ
Sbjct: 1536 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595
Query: 48 KKLKGTEDEVEKYSESEKAADESER----GMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
++L E E+E + A +++ +K +E +A + E QL++ + +
Sbjct: 1596 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYS- 162
D R+ E+ + + +E++A+ E+ QL+E+L ++A K +EE +
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1715
Query: 163 -------------TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLA- 208
++ + E I LEE+L+E + E V K + + L LA
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT 1775
Query: 209 --SAKEENVEIHQTLDQTLLELNN 230
S ++N Q L++ EL +
Sbjct: 1776 ERSTAQKNESARQQLERQNKELRS 1799
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 30/214 (14%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K + L+ E + E+ E + + ED +LE QA LKG ++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----LKG------QFERD 1579
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A DE ++EEK + QL E + ED ++ A LEG+L
Sbjct: 1580 LQARDE-------------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626
Query: 124 ERSEERA-------EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE 176
+ E +A E A + R+L+ +++ + L+ AS +E + E++ K LE
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 177 EKLKEAETRAEFAERSVAKLEKTIDDLEETLASA 210
L + + AER+ + + ++L E LAS+
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Score = 50.8 bits (120), Expect = 1e-06
Identities = 58/206 (28%), Positives = 96/206 (46%), Gaps = 24/206 (11%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
QA++ K E+ KQL + Q ++ + ED E A E+E+ K +E
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE----- 1686
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESRARQLEE 142
+ M+LQE L A+ + +D + EE+A +L L G +E+ + E+R QLEE
Sbjct: 1687 -ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEE 1743
Query: 143 ELR--------TMDQALKSLMASEE---EYSTKE---DKYEEEIKLLEEKLKEAETRAEF 188
EL D+ K+ +E+ E +T+ K E + LE + KE ++
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 189 AERSV-AKLEKTIDDLEETLASAKEE 213
E +V +K + TI LE +A +E+
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 10/237 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++ + ++++ K K N + E + + L + +Q ++ K K E +V+
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ-- 1262
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
E + + ER + ++ K + ++E L EA+ A + ++ +L +
Sbjct: 1263 -ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1321
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
L+ + ++ RQLEEE ++ L M +++ ++ ++KL+
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ 1381
Query: 181 EAETRAEFAERSVAKLEKTIDDL-----EETLASAKEENVE--IHQTLDQTLLELNN 230
+ + E E + +K I++L E+ A K E + + Q LD +++L+N
Sbjct: 1382 DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Score = 48.1 bits (113), Expect = 6e-06
Identities = 61/243 (25%), Positives = 109/243 (44%), Gaps = 32/243 (13%)
Query: 13 LDKENAIDRAEQAEA---DKKQAEDRCKQLEEEQQALQKKLK-GTEDEVEKYSESEKAAD 68
L+KENA D A + K++ E + K+LE + Q LQ K G E + K +
Sbjct: 1229 LEKENA-DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 69 ESERGMKVI---ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
E E ++ E +A+K + + QL++ + + ++ R+ V+ KL LE E
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 126 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 185
+++ + + LE + T++ L +++++ ++ LEE K +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST-------VEALEEGKKRFQKE 1400
Query: 186 AE-----FAERSVA--KLEKT-------IDDLEETLASAKE--ENVEIHQ-TLDQTLLEL 228
E + E++ A KLEKT +DDL L + ++ N+E Q DQ L E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 229 NNL 231
N+
Sbjct: 1461 KNI 1463
Score = 47.8 bits (112), Expect = 8e-06
Identities = 40/201 (19%), Positives = 93/201 (46%), Gaps = 14/201 (6%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
Q KK+ +D +E ++ ++ K E+ ++Y E A D+ E+ +NR +
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQ 1427
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 143
+ + + + ++ E RK++++ + + + +RAE + AR+ E +
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE---AEAREKETK 1484
Query: 144 LRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 203
++ +AL+ + ++EE E K+L+ ++++ + + ++V +LEK+ L
Sbjct: 1485 ALSLARALEEALEAKEE-------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 204 EETLASAKEENVEIHQTLDQT 224
E + K + E+ L T
Sbjct: 1538 ETQMEEMKTQLEELEDELQAT 1558
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/187 (20%), Positives = 85/187 (45%), Gaps = 16/187 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+A+ +++ E + + ++ E +QLE + + L+ KL E V+
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK 1811
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
+S AA +E + + EE++E + + + A + D+K +E+ ++
Sbjct: 1812 FKSTIAA---------LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE-------EIK 173
E+ +E+AE +R +QL+ +L ++ + + A+ + + D+ E E+
Sbjct: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1922
Query: 174 LLEEKLK 180
L+ KL+
Sbjct: 1923 ALKSKLR 1929
Score = 45.1 bits (105), Expect = 5e-05
Identities = 48/230 (20%), Positives = 94/230 (40%), Gaps = 13/230 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KKK+Q D + ++ E+ + ++ + Q EE+ A KL+ T++ +++ E +
Sbjct: 1377 KKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ--ELD 1430
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV------- 117
+ + +++ N K + +L + + A++ DR E K
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
LE LE EE + ++E+ + + D K++ E+ E + EE LEE
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 227
E + + R ++ E L + E+N E + L + L E
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Score = 42.0 bits (97), Expect = 4e-04
Identities = 31/145 (21%), Positives = 66/145 (45%), Gaps = 9/145 (6%)
Query: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAM 82
EQ E + ++ + K L+++ + L++ L EDE + + ++ A++ +K ++ +
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 83 KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESR------ 136
+ EE+ + ++ + +++ E + R++ L+ +L R E + V R
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRV 1947
Query: 137 ---ARQLEEELRTMDQALKSLMASE 158
A EEE T D ASE
Sbjct: 1948 IENADGSEEETDTRDADFNGTKASE 1972
Score = 41.2 bits (95), Expect = 8e-04
Identities = 45/221 (20%), Positives = 92/221 (41%), Gaps = 21/221 (9%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
+ K + L ++ + ++ K + +QLEEE+ +LQ +L E
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL----------DEE 1355
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A ER + + + ++K++ E+ +++++ L E
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEK 1411
Query: 124 ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAE 183
+ ++ E ++R +Q ++L + L+++ E+ K D+ E K + K +
Sbjct: 1412 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 224
RAE R EK L +LA A EE +E + L++T
Sbjct: 1472 DRAEAEAR-----EKETKAL--SLARALEEALEAKEELERT 1505
Score = 33.5 bits (75), Expect = 0.16
Identities = 15/80 (18%), Positives = 41/80 (51%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKA 66
+++ LK E A + +++ A++++ + + E +A+ +++ + ++ + +E+
Sbjct: 1878 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFV 1937
Query: 67 ADESERGMKVIENRAMKDEE 86
G +VIEN +EE
Sbjct: 1938 PSRRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 71.6 bits (174), Expect = 5e-13
Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 24/245 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
+++MQ + + + +R ++AE + K+ E + QL EE+ LQ++L+ E E Y+E+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 65 K-----AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE----DSDRKYEEVARK 115
+ AA + E + E A +EE+ Q++Q + K + + + EE AR+
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 116 LVILE-----GELERSEERAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTK--- 164
+ LE ++++ E+ V + + +L +E + +++ + L +A EEE +
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 165 -EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++K+E I LE +LK+ E + E+ KLE D E +A + + E+ L +
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 224 TLLEL 228
EL
Sbjct: 1095 KEEEL 1099
Score = 60.8 bits (146), Expect = 9e-10
Identities = 43/189 (22%), Positives = 92/189 (48%), Gaps = 15/189 (7%)
Query: 28 DKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDE-- 85
+K++ E R QLEEE + Q ++ D V K ++ A++ + + A K+E
Sbjct: 1737 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ---AEQLSNELATERSTAQKNESA 1793
Query: 86 -EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
+++E Q +L+ H E + + + + LE ++ + EE+ E + + L
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKS--KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1851
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEE-------IKLLEEKLKEAETRAEFAERSVAKLE 197
+ D+ LK ++ E+ ++Y+E+ +K L+ +L+EAE ++ + KL+
Sbjct: 1852 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1911
Query: 198 KTIDDLEET 206
+ +D+ E+
Sbjct: 1912 RELDEATES 1920
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/238 (23%), Positives = 117/238 (49%), Gaps = 21/238 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY---- 60
+KK + L+ D + AE +KQA+ ++L EE + +DE +
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-------RKYEEVA 113
++ E+ +E + M+ + +R K ++ E +L + A+ ++ R+ +E+
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Query: 114 RKLVILEGELERSEERAEVA--ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE 171
KL +EG + +S+ ++ +A E++ QLEE++ +Q + A+ + K+ K +E
Sbjct: 1806 SKLHEMEGAV-KSKFKSTIAALEAKIAQLEEQV---EQEAREKQAATKSLKQKDKKLKEI 1861
Query: 172 IKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
+ +E++ K AE E AE+ A++++ LEE A+EE+ I+ + EL+
Sbjct: 1862 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEE----AEEESQRINANRRKLQRELD 1915
Score = 58.5 bits (140), Expect = 5e-09
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Query: 16 ENAIDRAEQAEADKK----QAEDRCKQLEEEQQALQK----------KLKGTEDEV---- 57
E DR +Q +A++K Q D +QLEEE+ A QK K+K EDE+
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 58 ---EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR 114
K S+ K +E R + N A ++E+ L +++ K I+E
Sbjct: 999 DQNNKLSKERKLLEE--RISDLTTNLAEEEEKAKNLTKLKNKHESMISE----------- 1045
Query: 115 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 174
LE L++ E+ + E R+LE + + + L A E + K EEE++
Sbjct: 1046 ----LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1101
Query: 175 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 211
+L + + A + + +LE I DL+E L S +
Sbjct: 1102 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1138
Score = 53.9 bits (128), Expect = 1e-07
Identities = 56/267 (20%), Positives = 107/267 (40%), Gaps = 42/267 (15%)
Query: 7 KMQMLKLDKE--NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KMQ+ K ++E A+ R + A K A + ++LE LQ+ L K + +
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 65 KAADESERGMKVI------------ENRAMKDEE---------------KMELQEMQLKE 97
+ E +K E RA +++E + ++QEM+ K
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 98 AKHIAE-------------DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
A+ + E + D+ + + ++ L GEL + + E + ++LE ++
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 204
+ + + E + K K + E++ + L EAE +A + VA L + D +
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1328
Query: 205 ETLASAKEENVEIHQTLDQTLLELNNL 231
E L + + + L Q E N+L
Sbjct: 1329 ELLQEETRQKLNVSTKLRQLEEERNSL 1355
Score = 51.6 bits (122), Expect = 6e-07
Identities = 49/202 (24%), Positives = 93/202 (46%), Gaps = 11/202 (5%)
Query: 13 LDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESER 72
LD+E A+ E +K A+ ++L E+ + K+ K D+ ++ E E A E
Sbjct: 1190 LDEETRSHEAQVQEMRQKHAQ-AVEELTEQLEQF-KRAKANLDKNKQTLEKENADLAGE- 1246
Query: 73 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 132
++V+ + E K + E Q++E + D +R E+ K+ L+ E+E
Sbjct: 1247 -LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 133 AESRARQLEEELRTMDQALKSLMASEEE-------YSTKEDKYEEEIKLLEEKLKEAETR 185
AE +A +L +++ ++ L+ +E STK + EEE L+++L E
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1365
Query: 186 AEFAERSVAKLEKTIDDLEETL 207
+ ER ++ L + D ++ L
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKL 1387
Score = 51.2 bits (121), Expect = 7e-07
Identities = 58/264 (21%), Positives = 112/264 (42%), Gaps = 36/264 (13%)
Query: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAE---------------DRCKQLEEEQQALQ 47
A++ +M+ +K E D + E K + E R +Q EE+++ LQ
Sbjct: 1543 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1602
Query: 48 KKLKGTEDEVEKYSESEKAADESER----GMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
++L E E+E + A +++ +K +E +A + E QL++ + +
Sbjct: 1603 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYS- 162
D R+ E+ + + +E++A+ E+ QL+E+L ++A K +EE +
Sbjct: 1663 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1722
Query: 163 -------------TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLA- 208
++ + E I LEE+L+E + E V K + + L LA
Sbjct: 1723 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT 1782
Query: 209 --SAKEENVEIHQTLDQTLLELNN 230
S ++N Q L++ EL +
Sbjct: 1783 ERSTAQKNESARQQLERQNKELRS 1806
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 30/214 (14%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K + L+ E + E+ E + + ED +LE QA LKG ++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----LKG------QFERD 1586
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A DE ++EEK + QL E + ED ++ A LEG+L
Sbjct: 1587 LQARDE-------------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633
Query: 124 ERSEERA-------EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE 176
+ E +A E A + R+L+ +++ + L+ AS +E + E++ K LE
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Query: 177 EKLKEAETRAEFAERSVAKLEKTIDDLEETLASA 210
L + + AER+ + + ++L E LAS+
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Score = 50.8 bits (120), Expect = 1e-06
Identities = 58/206 (28%), Positives = 96/206 (46%), Gaps = 24/206 (11%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
QA++ K E+ KQL + Q ++ + ED E A E+E+ K +E
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE----- 1693
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESRARQLEE 142
+ M+LQE L A+ + +D + EE+A +L L G +E+ + E+R QLEE
Sbjct: 1694 -ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEE 1750
Query: 143 ELR--------TMDQALKSLMASEE---EYSTKE---DKYEEEIKLLEEKLKEAETRAEF 188
EL D+ K+ +E+ E +T+ K E + LE + KE ++
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 189 AERSV-AKLEKTIDDLEETLASAKEE 213
E +V +K + TI LE +A +E+
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 10/237 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++ + ++++ K K N + E + + L + +Q ++ K K E +V+
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ-- 1269
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
E + + ER + ++ K + ++E L EA+ A + ++ +L +
Sbjct: 1270 -ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1328
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
L+ + ++ RQLEEE ++ L M +++ ++ ++KL+
Sbjct: 1329 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ 1388
Query: 181 EAETRAEFAERSVAKLEKTIDDL-----EETLASAKEENVE--IHQTLDQTLLELNN 230
+ + E E + +K I++L E+ A K E + + Q LD +++L+N
Sbjct: 1389 DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Score = 48.1 bits (113), Expect = 6e-06
Identities = 61/243 (25%), Positives = 109/243 (44%), Gaps = 32/243 (13%)
Query: 13 LDKENAIDRAEQAEA---DKKQAEDRCKQLEEEQQALQKKLK-GTEDEVEKYSESEKAAD 68
L+KENA D A + K++ E + K+LE + Q LQ K G E + K +
Sbjct: 1236 LEKENA-DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 69 ESERGMKVI---ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
E E ++ E +A+K + + QL++ + + ++ R+ V+ KL LE E
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 126 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 185
+++ + + LE + T++ L +++++ ++ LEE K +
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST-------VEALEEGKKRFQKE 1407
Query: 186 AE-----FAERSVA--KLEKT-------IDDLEETLASAKE--ENVEIHQ-TLDQTLLEL 228
E + E++ A KLEKT +DDL L + ++ N+E Q DQ L E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 229 NNL 231
N+
Sbjct: 1468 KNI 1470
Score = 47.8 bits (112), Expect = 8e-06
Identities = 40/201 (19%), Positives = 93/201 (46%), Gaps = 14/201 (6%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
Q KK+ +D +E ++ ++ K E+ ++Y E A D+ E+ +NR +
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQ 1434
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 143
+ + + + ++ E RK++++ + + + +RAE + AR+ E +
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE---AEAREKETK 1491
Query: 144 LRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 203
++ +AL+ + ++EE E K+L+ ++++ + + ++V +LEK+ L
Sbjct: 1492 ALSLARALEEALEAKEE-------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 204 EETLASAKEENVEIHQTLDQT 224
E + K + E+ L T
Sbjct: 1545 ETQMEEMKTQLEELEDELQAT 1565
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/187 (20%), Positives = 85/187 (45%), Gaps = 16/187 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+A+ +++ E + + ++ E +QLE + + L+ KL E V+
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK 1818
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
+S AA +E + + EE++E + + + A + D+K +E+ ++
Sbjct: 1819 FKSTIAA---------LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE-------EIK 173
E+ +E+AE +R +QL+ +L ++ + + A+ + + D+ E E+
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1929
Query: 174 LLEEKLK 180
L+ KL+
Sbjct: 1930 ALKSKLR 1936
Score = 45.1 bits (105), Expect = 5e-05
Identities = 48/230 (20%), Positives = 94/230 (40%), Gaps = 13/230 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KKK+Q D + ++ E+ + ++ + Q EE+ A KL+ T++ +++ E +
Sbjct: 1384 KKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ--ELD 1437
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV------- 117
+ + +++ N K + +L + + A++ DR E K
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
LE LE EE + ++E+ + + D K++ E+ E + EE LEE
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 227
E + + R ++ E L + E+N E + L + L E
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Score = 42.0 bits (97), Expect = 4e-04
Identities = 31/145 (21%), Positives = 66/145 (45%), Gaps = 9/145 (6%)
Query: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAM 82
EQ E + ++ + K L+++ + L++ L EDE + + ++ A++ +K ++ +
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1894
Query: 83 KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESR------ 136
+ EE+ + ++ + +++ E + R++ L+ +L R E + V R
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRV 1954
Query: 137 ---ARQLEEELRTMDQALKSLMASE 158
A EEE T D ASE
Sbjct: 1955 IENADGSEEETDTRDADFNGTKASE 1979
Score = 41.2 bits (95), Expect = 8e-04
Identities = 45/221 (20%), Positives = 92/221 (41%), Gaps = 21/221 (9%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
+ K + L ++ + ++ K + +QLEEE+ +LQ +L E
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL----------DEE 1362
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A ER + + + ++K++ E+ +++++ L E
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEK 1418
Query: 124 ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAE 183
+ ++ E ++R +Q ++L + L+++ E+ K D+ E K + K +
Sbjct: 1419 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1478
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 224
RAE R EK L +LA A EE +E + L++T
Sbjct: 1479 DRAEAEAR-----EKETKAL--SLARALEEALEAKEELERT 1512
Score = 33.5 bits (75), Expect = 0.16
Identities = 15/80 (18%), Positives = 41/80 (51%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKA 66
+++ LK E A + +++ A++++ + + E +A+ +++ + ++ + +E+
Sbjct: 1885 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFV 1944
Query: 67 ADESERGMKVIENRAMKDEE 86
G +VIEN +EE
Sbjct: 1945 PSRRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 71.6 bits (174), Expect = 5e-13
Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 24/245 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
+++MQ + + + +R ++AE + K+ E + QL EE+ LQ++L+ E E Y+E+E
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 65 K-----AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE----DSDRKYEEVARK 115
+ AA + E + E A +EE+ Q++Q + K + + + EE AR+
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 116 LVILE-----GELERSEERAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTK--- 164
+ LE ++++ E+ V + + +L +E + +++ + L +A EEE +
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 165 -EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++K+E I LE +LK+ E + E+ KLE D E +A + + E+ L +
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 224 TLLEL 228
EL
Sbjct: 1095 KEEEL 1099
Score = 60.8 bits (146), Expect = 9e-10
Identities = 43/189 (22%), Positives = 92/189 (48%), Gaps = 15/189 (7%)
Query: 28 DKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDE-- 85
+K++ E R QLEEE + Q ++ D V K ++ A++ + + A K+E
Sbjct: 1737 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ---AEQLSNELATERSTAQKNESA 1793
Query: 86 -EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
+++E Q +L+ H E + + + + LE ++ + EE+ E + + L
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKS--KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1851
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEE-------IKLLEEKLKEAETRAEFAERSVAKLE 197
+ D+ LK ++ E+ ++Y+E+ +K L+ +L+EAE ++ + KL+
Sbjct: 1852 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1911
Query: 198 KTIDDLEET 206
+ +D+ E+
Sbjct: 1912 RELDEATES 1920
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/238 (23%), Positives = 117/238 (49%), Gaps = 21/238 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY---- 60
+KK + L+ D + AE +KQA+ ++L EE + +DE +
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-------RKYEEVA 113
++ E+ +E + M+ + +R K ++ E +L + A+ ++ R+ +E+
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Query: 114 RKLVILEGELERSEERAEVA--ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE 171
KL +EG + +S+ ++ +A E++ QLEE++ +Q + A+ + K+ K +E
Sbjct: 1806 SKLHEMEGAV-KSKFKSTIAALEAKIAQLEEQV---EQEAREKQAATKSLKQKDKKLKEI 1861
Query: 172 IKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
+ +E++ K AE E AE+ A++++ LEE A+EE+ I+ + EL+
Sbjct: 1862 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEE----AEEESQRINANRRKLQRELD 1915
Score = 58.5 bits (140), Expect = 5e-09
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Query: 16 ENAIDRAEQAEADKK----QAEDRCKQLEEEQQALQK----------KLKGTEDEV---- 57
E DR +Q +A++K Q D +QLEEE+ A QK K+K EDE+
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 58 ---EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR 114
K S+ K +E R + N A ++E+ L +++ K I+E
Sbjct: 999 DQNNKLSKERKLLEE--RISDLTTNLAEEEEKAKNLTKLKNKHESMISE----------- 1045
Query: 115 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 174
LE L++ E+ + E R+LE + + + L A E + K EEE++
Sbjct: 1046 ----LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1101
Query: 175 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 211
+L + + A + + +LE I DL+E L S +
Sbjct: 1102 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1138
Score = 53.9 bits (128), Expect = 1e-07
Identities = 56/267 (20%), Positives = 107/267 (40%), Gaps = 42/267 (15%)
Query: 7 KMQMLKLDKE--NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KMQ+ K ++E A+ R + A K A + ++LE LQ+ L K + +
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 65 KAADESERGMKVI------------ENRAMKDEE---------------KMELQEMQLKE 97
+ E +K E RA +++E + ++QEM+ K
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 98 AKHIAE-------------DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
A+ + E + D+ + + ++ L GEL + + E + ++LE ++
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 204
+ + + E + K K + E++ + L EAE +A + VA L + D +
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1328
Query: 205 ETLASAKEENVEIHQTLDQTLLELNNL 231
E L + + + L Q E N+L
Sbjct: 1329 ELLQEETRQKLNVSTKLRQLEEERNSL 1355
Score = 51.6 bits (122), Expect = 6e-07
Identities = 49/202 (24%), Positives = 93/202 (46%), Gaps = 11/202 (5%)
Query: 13 LDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESER 72
LD+E A+ E +K A+ ++L E+ + K+ K D+ ++ E E A E
Sbjct: 1190 LDEETRSHEAQVQEMRQKHAQ-AVEELTEQLEQF-KRAKANLDKNKQTLEKENADLAGE- 1246
Query: 73 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 132
++V+ + E K + E Q++E + D +R E+ K+ L+ E+E
Sbjct: 1247 -LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 133 AESRARQLEEELRTMDQALKSLMASEEE-------YSTKEDKYEEEIKLLEEKLKEAETR 185
AE +A +L +++ ++ L+ +E STK + EEE L+++L E
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1365
Query: 186 AEFAERSVAKLEKTIDDLEETL 207
+ ER ++ L + D ++ L
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKL 1387
Score = 51.2 bits (121), Expect = 7e-07
Identities = 58/264 (21%), Positives = 112/264 (42%), Gaps = 36/264 (13%)
Query: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAE---------------DRCKQLEEEQQALQ 47
A++ +M+ +K E D + E K + E R +Q EE+++ LQ
Sbjct: 1543 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1602
Query: 48 KKLKGTEDEVEKYSESEKAADESER----GMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
++L E E+E + A +++ +K +E +A + E QL++ + +
Sbjct: 1603 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYS- 162
D R+ E+ + + +E++A+ E+ QL+E+L ++A K +EE +
Sbjct: 1663 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1722
Query: 163 -------------TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLA- 208
++ + E I LEE+L+E + E V K + + L LA
Sbjct: 1723 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT 1782
Query: 209 --SAKEENVEIHQTLDQTLLELNN 230
S ++N Q L++ EL +
Sbjct: 1783 ERSTAQKNESARQQLERQNKELRS 1806
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 30/214 (14%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K + L+ E + E+ E + + ED +LE QA LKG ++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----LKG------QFERD 1586
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A DE ++EEK + QL E + ED ++ A LEG+L
Sbjct: 1587 LQARDE-------------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633
Query: 124 ERSEERA-------EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE 176
+ E +A E A + R+L+ +++ + L+ AS +E + E++ K LE
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Query: 177 EKLKEAETRAEFAERSVAKLEKTIDDLEETLASA 210
L + + AER+ + + ++L E LAS+
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Score = 50.8 bits (120), Expect = 1e-06
Identities = 58/206 (28%), Positives = 96/206 (46%), Gaps = 24/206 (11%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
QA++ K E+ KQL + Q ++ + ED E A E+E+ K +E
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE----- 1693
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESRARQLEE 142
+ M+LQE L A+ + +D + EE+A +L L G +E+ + E+R QLEE
Sbjct: 1694 -ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEE 1750
Query: 143 ELR--------TMDQALKSLMASEE---EYSTKE---DKYEEEIKLLEEKLKEAETRAEF 188
EL D+ K+ +E+ E +T+ K E + LE + KE ++
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 189 AERSV-AKLEKTIDDLEETLASAKEE 213
E +V +K + TI LE +A +E+
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 10/237 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++ + ++++ K K N + E + + L + +Q ++ K K E +V+
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ-- 1269
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
E + + ER + ++ K + ++E L EA+ A + ++ +L +
Sbjct: 1270 -ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1328
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
L+ + ++ RQLEEE ++ L M +++ ++ ++KL+
Sbjct: 1329 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ 1388
Query: 181 EAETRAEFAERSVAKLEKTIDDL-----EETLASAKEENVE--IHQTLDQTLLELNN 230
+ + E E + +K I++L E+ A K E + + Q LD +++L+N
Sbjct: 1389 DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Score = 48.1 bits (113), Expect = 6e-06
Identities = 61/243 (25%), Positives = 109/243 (44%), Gaps = 32/243 (13%)
Query: 13 LDKENAIDRAEQAEA---DKKQAEDRCKQLEEEQQALQKKLK-GTEDEVEKYSESEKAAD 68
L+KENA D A + K++ E + K+LE + Q LQ K G E + K +
Sbjct: 1236 LEKENA-DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 69 ESERGMKVI---ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
E E ++ E +A+K + + QL++ + + ++ R+ V+ KL LE E
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 126 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 185
+++ + + LE + T++ L +++++ ++ LEE K +
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST-------VEALEEGKKRFQKE 1407
Query: 186 AE-----FAERSVA--KLEKT-------IDDLEETLASAKE--ENVEIHQ-TLDQTLLEL 228
E + E++ A KLEKT +DDL L + ++ N+E Q DQ L E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 229 NNL 231
N+
Sbjct: 1468 KNI 1470
Score = 47.8 bits (112), Expect = 8e-06
Identities = 40/201 (19%), Positives = 93/201 (46%), Gaps = 14/201 (6%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
Q KK+ +D +E ++ ++ K E+ ++Y E A D+ E+ +NR +
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQ 1434
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 143
+ + + + ++ E RK++++ + + + +RAE + AR+ E +
Sbjct: 1435 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE---AEAREKETK 1491
Query: 144 LRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 203
++ +AL+ + ++EE E K+L+ ++++ + + ++V +LEK+ L
Sbjct: 1492 ALSLARALEEALEAKEE-------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 204 EETLASAKEENVEIHQTLDQT 224
E + K + E+ L T
Sbjct: 1545 ETQMEEMKTQLEELEDELQAT 1565
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/187 (20%), Positives = 85/187 (45%), Gaps = 16/187 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+A+ +++ E + + ++ E +QLE + + L+ KL E V+
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK 1818
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
+S AA +E + + EE++E + + + A + D+K +E+ ++
Sbjct: 1819 FKSTIAA---------LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE-------EIK 173
E+ +E+AE +R +QL+ +L ++ + + A+ + + D+ E E+
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1929
Query: 174 LLEEKLK 180
L+ KL+
Sbjct: 1930 ALKSKLR 1936
Score = 45.1 bits (105), Expect = 5e-05
Identities = 48/230 (20%), Positives = 94/230 (40%), Gaps = 13/230 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KKK+Q D + ++ E+ + ++ + Q EE+ A KL+ T++ +++ E +
Sbjct: 1384 KKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ--ELD 1437
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV------- 117
+ + +++ N K + +L + + A++ DR E K
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
LE LE EE + ++E+ + + D K++ E+ E + EE LEE
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 227
E + + R ++ E L + E+N E + L + L E
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Score = 41.2 bits (95), Expect = 8e-04
Identities = 45/221 (20%), Positives = 92/221 (41%), Gaps = 21/221 (9%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
+ K + L ++ + ++ K + +QLEEE+ +LQ +L E
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL----------DEE 1362
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A ER + + + ++K++ E+ +++++ L E
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEK 1418
Query: 124 ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAE 183
+ ++ E ++R +Q ++L + L+++ E+ K D+ E K + K +
Sbjct: 1419 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1478
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 224
RAE R EK L +LA A EE +E + L++T
Sbjct: 1479 DRAEAEAR-----EKETKAL--SLARALEEALEAKEELERT 1512
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 71.6 bits (174), Expect = 5e-13
Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 24/245 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
+++MQ + + + +R ++AE + K+ E + QL EE+ LQ++L+ E E Y+E+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 65 K-----AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE----DSDRKYEEVARK 115
+ AA + E + E A +EE+ Q++Q + K + + + EE AR+
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 116 LVILE-----GELERSEERAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTK--- 164
+ LE ++++ E+ V + + +L +E + +++ + L +A EEE +
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 165 -EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++K+E I LE +LK+ E + E+ KLE D E +A + + E+ L +
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 224 TLLEL 228
EL
Sbjct: 1088 KEEEL 1092
Score = 60.8 bits (146), Expect = 9e-10
Identities = 43/189 (22%), Positives = 92/189 (48%), Gaps = 15/189 (7%)
Query: 28 DKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDE-- 85
+K++ E R QLEEE + Q ++ D V K ++ A++ + + A K+E
Sbjct: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ---AEQLSNELATERSTAQKNESA 1786
Query: 86 -EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
+++E Q +L+ H E + + + + LE ++ + EE+ E + + L
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKS--KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1844
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEE-------IKLLEEKLKEAETRAEFAERSVAKLE 197
+ D+ LK ++ E+ ++Y+E+ +K L+ +L+EAE ++ + KL+
Sbjct: 1845 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ 1904
Query: 198 KTIDDLEET 206
+ +D+ E+
Sbjct: 1905 RELDEATES 1913
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/238 (23%), Positives = 117/238 (49%), Gaps = 21/238 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY---- 60
+KK + L+ D + AE +KQA+ ++L EE + +DE +
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-------RKYEEVA 113
++ E+ +E + M+ + +R K ++ E +L + A+ ++ R+ +E+
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Query: 114 RKLVILEGELERSEERAEVA--ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE 171
KL +EG + +S+ ++ +A E++ QLEE++ +Q + A+ + K+ K +E
Sbjct: 1799 SKLHEMEGAV-KSKFKSTIAALEAKIAQLEEQV---EQEAREKQAATKSLKQKDKKLKEI 1854
Query: 172 IKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 229
+ +E++ K AE E AE+ A++++ LEE A+EE+ I+ + EL+
Sbjct: 1855 LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEE----AEEESQRINANRRKLQRELD 1908
Score = 58.5 bits (140), Expect = 5e-09
Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Query: 16 ENAIDRAEQAEADKK----QAEDRCKQLEEEQQALQK----------KLKGTEDEV---- 57
E DR +Q +A++K Q D +QLEEE+ A QK K+K EDE+
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 58 ---EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR 114
K S+ K +E R + N A ++E+ L +++ K I+E
Sbjct: 992 DQNNKLSKERKLLEE--RISDLTTNLAEEEEKAKNLTKLKNKHESMISE----------- 1038
Query: 115 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 174
LE L++ E+ + E R+LE + + + L A E + K EEE++
Sbjct: 1039 ----LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094
Query: 175 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 211
+L + + A + + +LE I DL+E L S +
Sbjct: 1095 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131
Score = 53.9 bits (128), Expect = 1e-07
Identities = 56/267 (20%), Positives = 107/267 (40%), Gaps = 42/267 (15%)
Query: 7 KMQMLKLDKE--NAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KMQ+ K ++E A+ R + A K A + ++LE LQ+ L K + +
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 65 KAADESERGMKVI------------ENRAMKDEE---------------KMELQEMQLKE 97
+ E +K E RA +++E + ++QEM+ K
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 98 AKHIAE-------------DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 144
A+ + E + D+ + + ++ L GEL + + E + ++LE ++
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 145 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 204
+ + + E + K K + E++ + L EAE +A + VA L + D +
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1321
Query: 205 ETLASAKEENVEIHQTLDQTLLELNNL 231
E L + + + L Q E N+L
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEEERNSL 1348
Score = 51.6 bits (122), Expect = 6e-07
Identities = 49/202 (24%), Positives = 93/202 (46%), Gaps = 11/202 (5%)
Query: 13 LDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESER 72
LD+E A+ E +K A+ ++L E+ + K+ K D+ ++ E E A E
Sbjct: 1183 LDEETRSHEAQVQEMRQKHAQ-AVEELTEQLEQF-KRAKANLDKNKQTLEKENADLAGE- 1239
Query: 73 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 132
++V+ + E K + E Q++E + D +R E+ K+ L+ E+E
Sbjct: 1240 -LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 133 AESRARQLEEELRTMDQALKSLMASEEE-------YSTKEDKYEEEIKLLEEKLKEAETR 185
AE +A +L +++ ++ L+ +E STK + EEE L+++L E
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
Query: 186 AEFAERSVAKLEKTIDDLEETL 207
+ ER ++ L + D ++ L
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKL 1380
Score = 51.2 bits (121), Expect = 7e-07
Identities = 58/264 (21%), Positives = 112/264 (42%), Gaps = 36/264 (13%)
Query: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAE---------------DRCKQLEEEQQALQ 47
A++ +M+ +K E D + E K + E R +Q EE+++ LQ
Sbjct: 1536 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595
Query: 48 KKLKGTEDEVEKYSESEKAADESER----GMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
++L E E+E + A +++ +K +E +A + E QL++ + +
Sbjct: 1596 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYS- 162
D R+ E+ + + +E++A+ E+ QL+E+L ++A K +EE +
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1715
Query: 163 -------------TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLA- 208
++ + E I LEE+L+E + E V K + + L LA
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT 1775
Query: 209 --SAKEENVEIHQTLDQTLLELNN 230
S ++N Q L++ EL +
Sbjct: 1776 ERSTAQKNESARQQLERQNKELRS 1799
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 30/214 (14%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K + L+ E + E+ E + + ED +LE QA LKG ++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA----LKG------QFERD 1579
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A DE ++EEK + QL E + ED ++ A LEG+L
Sbjct: 1580 LQARDE-------------QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626
Query: 124 ERSEERA-------EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE 176
+ E +A E A + R+L+ +++ + L+ AS +E + E++ K LE
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 177 EKLKEAETRAEFAERSVAKLEKTIDDLEETLASA 210
L + + AER+ + + ++L E LAS+
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Score = 50.8 bits (120), Expect = 1e-06
Identities = 58/206 (28%), Positives = 96/206 (46%), Gaps = 24/206 (11%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
QA++ K E+ KQL + Q ++ + ED E A E+E+ K +E
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE----- 1686
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESRARQLEE 142
+ M+LQE L A+ + +D + EE+A +L L G +E+ + E+R QLEE
Sbjct: 1687 -ADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL-EARIAQLEE 1743
Query: 143 ELR--------TMDQALKSLMASEE---EYSTKE---DKYEEEIKLLEEKLKEAETRAEF 188
EL D+ K+ +E+ E +T+ K E + LE + KE ++
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 189 AERSV-AKLEKTIDDLEETLASAKEE 213
E +V +K + TI LE +A +E+
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 10/237 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++ + ++++ K K N + E + + L + +Q ++ K K E +V+
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ-- 1262
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
E + + ER + ++ K + ++E L EA+ A + ++ +L +
Sbjct: 1263 -ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 1321
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
L+ + ++ RQLEEE ++ L M +++ ++ ++KL+
Sbjct: 1322 ELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ 1381
Query: 181 EAETRAEFAERSVAKLEKTIDDL-----EETLASAKEENVE--IHQTLDQTLLELNN 230
+ + E E + +K I++L E+ A K E + + Q LD +++L+N
Sbjct: 1382 DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Score = 48.1 bits (113), Expect = 6e-06
Identities = 61/243 (25%), Positives = 109/243 (44%), Gaps = 32/243 (13%)
Query: 13 LDKENAIDRAEQAEA---DKKQAEDRCKQLEEEQQALQKKLK-GTEDEVEKYSESEKAAD 68
L+KENA D A + K++ E + K+LE + Q LQ K G E + K +
Sbjct: 1229 LEKENA-DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 69 ESERGMKVI---ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
E E ++ E +A+K + + QL++ + + ++ R+ V+ KL LE E
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 126 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 185
+++ + + LE + T++ L +++++ ++ LEE K +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST-------VEALEEGKKRFQKE 1400
Query: 186 AE-----FAERSVA--KLEKT-------IDDLEETLASAKE--ENVEIHQ-TLDQTLLEL 228
E + E++ A KLEKT +DDL L + ++ N+E Q DQ L E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 229 NNL 231
N+
Sbjct: 1461 KNI 1463
Score = 47.8 bits (112), Expect = 8e-06
Identities = 40/201 (19%), Positives = 93/201 (46%), Gaps = 14/201 (6%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMK 83
Q KK+ +D +E ++ ++ K E+ ++Y E A D+ E+ +NR +
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRLQQ 1427
Query: 84 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 143
+ + + + ++ E RK++++ + + + +RAE + AR+ E +
Sbjct: 1428 ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE---AEAREKETK 1484
Query: 144 LRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 203
++ +AL+ + ++EE E K+L+ ++++ + + ++V +LEK+ L
Sbjct: 1485 ALSLARALEEALEAKEE-------LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 204 EETLASAKEENVEIHQTLDQT 224
E + K + E+ L T
Sbjct: 1538 ETQMEEMKTQLEELEDELQAT 1558
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/187 (20%), Positives = 85/187 (45%), Gaps = 16/187 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+A+ +++ E + + ++ E +QLE + + L+ KL E V+
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK 1811
Query: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
+S AA +E + + EE++E + + + A + D+K +E+ ++
Sbjct: 1812 FKSTIAA---------LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE-------EIK 173
E+ +E+AE +R +QL+ +L ++ + + A+ + + D+ E E+
Sbjct: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1922
Query: 174 LLEEKLK 180
L+ KL+
Sbjct: 1923 ALKSKLR 1929
Score = 45.1 bits (105), Expect = 5e-05
Identities = 48/230 (20%), Positives = 94/230 (40%), Gaps = 13/230 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
KKK+Q D + ++ E+ + ++ + Q EE+ A KL+ T++ +++ E +
Sbjct: 1377 KKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ--ELD 1430
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV------- 117
+ + +++ N K + +L + + A++ DR E K
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
LE LE EE + ++E+ + + D K++ E+ E + EE LEE
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 227
E + + R ++ E L + E+N E + L + L E
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Score = 41.2 bits (95), Expect = 8e-04
Identities = 45/221 (20%), Positives = 92/221 (41%), Gaps = 21/221 (9%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
+ K + L ++ + ++ K + +QLEEE+ +LQ +L E
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL----------DEE 1355
Query: 64 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 123
+A ER + + + ++K++ E+ +++++ L E
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKKLQ----DFASTVEALEEGKKRFQKEIENLTQQYEEK 1411
Query: 124 ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAE 183
+ ++ E ++R +Q ++L + L+++ E+ K D+ E K + K +
Sbjct: 1412 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 224
RAE R EK L +LA A EE +E + L++T
Sbjct: 1472 DRAEAEAR-----EKETKAL--SLARALEEALEAKEELERT 1505
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 68.9 bits (167), Expect = 3e-12
Identities = 53/221 (23%), Positives = 105/221 (47%), Gaps = 19/221 (8%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEE----QQALQKKLKGTEDEVEKYS 61
+KMQ + +E EQ + +KK E K ++E +++++++ K +E E
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE----EVARKLV 117
E E+ E E M+ E + EEKM QE ++ E + + E ++ +E + K+
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQAL-----------KSLMASEEEYSTKED 166
E ++ EE+ E + R EE++R ++ + + + EE+ +E+
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 167 KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 207
K EE+++ EEK++E E + E + + E+ + EE +
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 64.7 bits (156), Expect = 6e-11
Identities = 54/219 (24%), Positives = 102/219 (46%), Gaps = 3/219 (1%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
+KKM + +E EQ E + Q + Q E ++ Q++ K T D+ EK E E
Sbjct: 530 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE 589
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE 124
+ E E+ M+ E + EEKM+ QE +++E + + + K +E K+ E ++
Sbjct: 590 RMR-EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Query: 125 RSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAET 184
EE+ + Q E+ + M +EE +++K E++ + E+K + E
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708
Query: 185 RAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
E E S+ + EK + + EE + +E+ E + + +
Sbjct: 709 MRE--EESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Score = 63.9 bits (154), Expect = 1e-10
Identities = 49/209 (23%), Positives = 104/209 (49%), Gaps = 11/209 (5%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERG 73
++E + E+ ++K+ ++ +Q++E+++ + ++ + ++ EK E+ E E+
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 74 MKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR-----KLVILEGELERSEE 128
M+ E + EE+M Q+ +L+E + + ++ +E+V + K+ E + EE
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 129 RAEVAE---SRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE--EKLKEAE 183
+ + E R +++ EE TM + + + EE +E+K ++ +L E EKL E E
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKE 212
E E + + E+ I D EE K+
Sbjct: 505 KMQE-QEEKIWEQEEKIRDQEEMWGQEKK 532
Score = 63.5 bits (153), Expect = 1e-10
Identities = 60/234 (25%), Positives = 115/234 (49%), Gaps = 27/234 (11%)
Query: 5 KKKMQMLKLDKENAIDRAE----QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV--- 57
K ++Q+ + + ++RA+ Q + + Q E+ +Q EEE + +KK++ E+++
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQ-EEMWRQ-EEELREQEKKIRKQEEKMWRQ 298
Query: 58 -EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE------ 110
E+ E E E E M E R + E+++ QE +L+E K + E ++ E
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358
Query: 111 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKED 166
E K+ E ++ R EER E + R+ E+++R ++ + + L EE +E
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 167 KYEEEIKLLEEKL---KEAETRAEFA----ERSVAKLEKTIDDLEETLASAKEE 213
+E+ K+ EEK +E +TR + E + + EK + + EET+ +E+
Sbjct: 419 MWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Score = 62.4 bits (150), Expect = 3e-10
Identities = 47/207 (22%), Positives = 98/207 (47%), Gaps = 10/207 (4%)
Query: 14 DKENAIDRAEQA----EADKKQAEDRCKQLEEEQQALQKKLKGTEDEV---EKYSESEKA 66
++E I + E+ E ++ E + ++ EE+ +K+L+ E E+ EK +K
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342
Query: 67 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 126
E E M+ E + + EEKM QE ++ + + +++ E +K+ E +
Sbjct: 343 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 402
Query: 127 EERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRA 186
+ER E R R+ E+ +++ + E+E T++ +EE EE+++E E +
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD---QEEKMQEEERIREREKKM 459
Query: 187 EFAERSVAKLEKTIDDLEETLASAKEE 213
E ++ + E+ + EE + +E+
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEK 486
Score = 60.5 bits (145), Expect = 1e-09
Identities = 50/225 (22%), Positives = 109/225 (48%), Gaps = 15/225 (6%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESE-- 71
++E + + E+ ++++ E + ++L E+++ L ++ K E E + + + EK D+ E
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 527
Query: 72 ---------RGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
M+ E++ + EEKM QE ++ + + E ++K +E +K E +
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE---ERMEKKTQEQEKKTWDQEEK 584
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEA 182
+ R EER E + R+ EE +R ++ ++ +E K + EE+++ EEK+ E
Sbjct: 585 M-REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 183 ETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 227
E + E + + ++ + E+ K + E Q ++ + E
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Score = 60.1 bits (144), Expect = 2e-09
Identities = 44/210 (20%), Positives = 104/210 (49%), Gaps = 18/210 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
+++M+ ++E E+ ++++ +R K++ EE++ ++++ + +++ EK E E
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE 124
+ E E M+ E + + EEKM QE ++ E + + E ++ +E E
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH------------E 671
Query: 125 RSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE-IKLLEEKLKEAE 183
+ +E+ ++ E EE++ ++ K E++ +E EEE ++ E+K++E E
Sbjct: 672 KMQEQEKMQE-----QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKEE 213
E + + E+ + + EE + +E+
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Score = 58.9 bits (141), Expect = 4e-09
Identities = 58/231 (25%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEE--EQQALQKKLKGTEDEVEKYSE 62
++KMQ + +E E+ E ++Q E KQ E EQ+ + + + ++ EK E
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 63 SEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
EK ++ E+ + + ++D+E+M QE ++ + + E D+ +E+ K+ E +
Sbjct: 503 QEKMQEQEEKIWE--QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-EEKMRDQEQK 559
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL------- 175
+ EER E + E+E +T DQ K M EE +E K EE +++
Sbjct: 560 MWDQEERME-----KKTQEQEKKTWDQEEK--MREEERMREREKKMREEEEMMREQEEKM 612
Query: 176 ---EEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
EEK++E E + E + + E+ + + EE + +E+ E + +Q
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Score = 58.2 bits (139), Expect = 6e-09
Identities = 53/231 (22%), Positives = 114/231 (49%), Gaps = 29/231 (12%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQA-EADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+ ++++ + ++ ++E ++ E+ E ++K E K E+E++ +++ K E E + +
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Query: 61 SESEKAADES---ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLV 117
+ EK ++ E+ K+ E+ M+++EKM+ QE ++ E E ++K +E +K
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ----EKMEKKTQEQEKKT- 703
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE- 176
+ E R EE E + R+ EE +R ++ ++ E+ +E+ +E+E K+ E
Sbjct: 704 -WDQEKMREEESMREREKKMREEEEMMREQEEKMQE--QEEKMQEQEEEMWEQEEKMWEQ 760
Query: 177 --------------EKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
EKL E E E + + + E+ + D EE + +E+
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQE--QEKIWEQEEKMRDQEEKMRGQEEK 809
Score = 57.8 bits (138), Expect = 8e-09
Identities = 47/179 (26%), Positives = 85/179 (47%), Gaps = 8/179 (4%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKD--EEKMELQEMQ 94
++L+++ LQ+KL E E + + K K + + + +E+M QE +
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 95 LKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL--- 151
L+E + + K +L EG++ EE+ E R R+ E+ELR ++ L
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 152 KSLMASEEEYSTKEDK---YEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 207
K L EE+ +E+K EE+++ EEK+ E R E+ + + E+ + D EE +
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 399
Score = 57.8 bits (138), Expect = 8e-09
Identities = 49/224 (21%), Positives = 106/224 (47%), Gaps = 13/224 (5%)
Query: 15 KENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGM 74
+E ++ E+ ++ E + K E E+ Q+K++ E+++ + + EK E E+
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK-- 701
Query: 75 KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAE 134
K + M++EE M +E +++E + + + + K +E K+ E E+ EE+ E
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 135 SRA---RQLEEELRTM-----DQALKSLMASEEEYSTKEDKY---EEEIKLLEEKLKEAE 183
+ ++L E+ + Q + + EE+ +E+K EE+++ EEK++ E
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 184 TRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 227
+ E + E+ + EE + +E+ E Q ++ + E
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865
Score = 53.9 bits (128), Expect = 1e-07
Identities = 53/245 (21%), Positives = 115/245 (46%), Gaps = 35/245 (14%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAE------DRCKQLEEEQQALQKKLKGTED 55
+ +++K + ++ ++E ++ E+ +KK E D+ ++++EE++ +++ K E+
Sbjct: 404 ERLREKEERMR-EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 56 EVEKYSESEKAADESERGMKVIENRAMK------------DEEKMELQEMQLKEAKHIAE 103
E E E E+ + E M E + + ++EKM+ QE ++ E +
Sbjct: 463 E-ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521
Query: 104 DSDRKYEEVAR-----KLVILEGELERSEERAEVAESRARQLEE--ELRTMDQALKS--- 153
D + + + + K+ E ++ EE+ E + EE E +T +Q K+
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Query: 154 --LMASEEEYSTKEDKYEEEIKLL---EEKLKEAETRAEFAERSVAKLEKTIDDLEETLA 208
M EE +E K EE +++ EEK++E E + + E + + E+ + + EE +
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641
Query: 209 SAKEE 213
+E+
Sbjct: 642 EQEEK 646
Score = 53.5 bits (127), Expect = 1e-07
Identities = 52/233 (22%), Positives = 106/233 (45%), Gaps = 27/233 (11%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEE---EQQAL----------- 46
M ++KMQ + ++ ++ E + E++ + EE EQQ L
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 47 ----QKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIA 102
Q+K++ E+++ + + EK E E+ K + M++EE M +E +++E + +
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEK--KTWDQEKMREEESMREREKKMREEEEMM 729
Query: 103 EDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYS 162
+ + K +E K+ E E+ EE+ E + + E+ R +Q K + E+
Sbjct: 730 REQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK---MWEQQRLPEQ--KEKLWEHEKMQ 784
Query: 163 TKEDKYEEEIKL--LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+E +E+E K+ EEK++ E + E + E+ + EE + +E+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK 837
Score = 52.8 bits (125), Expect = 3e-07
Identities = 45/189 (23%), Positives = 91/189 (48%), Gaps = 20/189 (10%)
Query: 39 LEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEA 98
L+EE +++L+ E ++ K + EK + ER ++ E + + EEKM QE +L+E
Sbjct: 270 LQEEMWRQEEELREQEKKIRK--QEEKMWRQEER-LREQEGKMREQEEKMWRQEKRLREQ 326
Query: 99 KHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL----KSL 154
+ + +++ E + EL EE+ + E + + EE++R ++ + + L
Sbjct: 327 EKELREQEKELRE--------QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 155 MASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEEN 214
E++ +E K ++ EE++ E + R E + + EK + +E+ K +
Sbjct: 379 WEQEKQMREQEQKMRDQ----EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 215 VEIHQTLDQ 223
E +T DQ
Sbjct: 435 QE-KKTRDQ 442
Score = 51.2 bits (121), Expect = 7e-07
Identities = 42/201 (20%), Positives = 91/201 (45%), Gaps = 3/201 (1%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKA 66
+ Q L KE ++ + E ++K E K ++E+ Q+K + EK E E
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ---EKMREQEDQ 545
Query: 67 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 126
E E M+ E + EE+ME + + ++ E+ R+ E + + + E E
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 127 EERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRA 186
E+ E + + +++E+ M + + + EE+ +E+K E+ + + E+ + E +
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Query: 187 EFAERSVAKLEKTIDDLEETL 207
+ E + ++ + + EE +
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKI 686
Score = 39.7 bits (91), Expect = 0.002
Identities = 43/190 (22%), Positives = 81/190 (42%), Gaps = 26/190 (13%)
Query: 53 TEDEVEKYSESEKAADESERGMKVIENRAMKDEEKME-------LQEMQLKEAKHIAEDS 105
++D + S A E +R + + R K + +E ++L E+
Sbjct: 164 SKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEEL 223
Query: 106 DRKYEEVARKLVILEGE----------LERSEERAE--VAESRARQLEEELRTMDQALKS 153
+K E+ KL + E E L+R ERA+ + + + L+EE+ ++ L+
Sbjct: 224 KKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR- 282
Query: 154 LMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
E K K EE++ EE+L+E E + E + + EK + + E+ L ++E
Sbjct: 283 ------EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 214 NVEIHQTLDQ 223
E + +Q
Sbjct: 337 LREQKELREQ 346
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 68.9 bits (167), Expect = 3e-12
Identities = 45/195 (23%), Positives = 98/195 (50%), Gaps = 5/195 (2%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ ++++ +M + +K+ + E ++K E K E+E++ +++ K E E + +
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 62 ESEKAADESERG-MKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 120
+ EK ++ E M+ E + EEKM+ QE ++ E + + + K E K+ E
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 121 GELERSEERAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKEDKYEEEIKLLE 176
++ EE+ + E + R+ EE++R ++ + + + EE+ +E+ E+E ++ +
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Query: 177 EKLKEAETRAEFAER 191
+K K E E ER
Sbjct: 734 QKEKMQERLPEHEER 748
Score = 68.6 bits (166), Expect = 4e-12
Identities = 57/228 (25%), Positives = 115/228 (50%), Gaps = 21/228 (9%)
Query: 5 KKKMQMLKLDKENAIDRAE----QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV--- 57
K ++Q+ + + ++RA+ Q + + Q E+ +Q EEE + +KK++ E+++
Sbjct: 203 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQ-EEMWRQ-EEELREQEKKIRKQEEKMWRQ 260
Query: 58 -EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE------ 110
E+ E E E E M+ E R + E+++ QE +L+E K + E ++ E
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320
Query: 111 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKED 166
E K+ E ++ R EER E + R+ E+++R ++ + + L EE +E
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Query: 167 KYEEEIKLLEE-KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+E+E K+ EE +++E E + E ++ + E+ + EE + +E+
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Score = 67.0 bits (162), Expect = 1e-11
Identities = 49/211 (23%), Positives = 106/211 (50%), Gaps = 10/211 (4%)
Query: 15 KENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGM 74
+E + ++ + +K+ D+ +++ EE++ +++ K E+E E E E+ E E M
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE-EMMREQEEKMQEQEEKM 590
Query: 75 KVIENRAMKDEEKMELQEMQL--KEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 132
+ E + + EEKM+ QE ++ +E K ++ + K +E + E +++ EE+
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 133 AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERS 192
E + R+ EE++R ++ ++ EE+ +E+K + + EEK++E E + E
Sbjct: 651 QEEKMREQEEKMREQEEKMQG---QEEKMREQEEKMQGQ----EEKMREQEEKMRGQEEK 703
Query: 193 VAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
+ E+ + EE + +E + + DQ
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Score = 63.5 bits (153), Expect = 1e-10
Identities = 53/225 (23%), Positives = 111/225 (49%), Gaps = 9/225 (4%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEE--EQQALQKKLKGTEDEVEKYSE 62
++KMQ + +E E+ E ++Q E KQ E EQ+ + + + ++ EK E
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 63 SEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
EK ++ E+ + + ++D+E+M QE ++ + + E D+ +E+ K+ E +
Sbjct: 445 QEKMQEQEEKIWE--QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-EEKMRDQEQK 501
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEIKLLEE-K 178
+ EER + R R+ EE +R + + EE T+E + +++E K+ EE +
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 179 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++E E + E + + E+ + + EE + +E+ E + + +
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE 606
Score = 63.5 bits (153), Expect = 1e-10
Identities = 45/203 (22%), Positives = 102/203 (50%), Gaps = 13/203 (6%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERG 73
D+E + ++ +K++ K++ ++++ ++++ K E E + + + EK +E
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER-- 561
Query: 74 MKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVA 133
M+ E + ++EE M QE +++E + K E K+ E +++ EE+
Sbjct: 562 MREREKKMREEEEMMREQEEKMQE-------QEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 134 ESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEIKLLEEKLKEAETRAEFAE 190
E + + EEE + +Q + + EE+ +E+K EE+++ EEK++E E + + E
Sbjct: 615 EEKMWEQEEEDKMQEQE-EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 191 RSVAKLEKTIDDLEETLASAKEE 213
+ + E+ + EE + +E+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEK 696
Score = 62.8 bits (151), Expect = 2e-10
Identities = 48/197 (24%), Positives = 96/197 (48%), Gaps = 8/197 (4%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERG 73
D+E + E+ +K+ + + + E+++ +Q++ + ++ EK E E+ E E
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 74 MKVIENRAMKDEE--KMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 131
M E + + EE KM+ QE + E + ++ + K E K+ E ++ EE+ +
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 132 VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEIKLLEEKLKEAETRAEF 188
E + R+ EE+++ ++ ++ EE+ +E+K EE++ EEK+ E E
Sbjct: 671 GQEEKMREQEEKMQGQEEKMRE---QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727
Query: 189 AERSVAKLEKTIDDLEE 205
ER + EK + L E
Sbjct: 728 EERIRDQKEKMQERLPE 744
Score = 60.8 bits (146), Expect = 9e-10
Identities = 47/201 (23%), Positives = 99/201 (49%), Gaps = 15/201 (7%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERG 73
++E + E+ ++K+ ++ +Q++E+++ + ++ + ++ EK E+ E E+
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 74 MKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVA 133
M+ E + EE+M Q+ +L+E + + ++ +E + E + EER
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE---------QEEKMQEEERIRER 397
Query: 134 ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE--EKLKEAETRAEFAER 191
E + R+ EE +R ++ ++ EE +E+K ++ +L E EKL E E E E
Sbjct: 398 EKKMREEEETMREQEEKMQK---QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE-QEE 453
Query: 192 SVAKLEKTIDDLEETLASAKE 212
+ + E+ I D EE K+
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKK 474
Score = 60.5 bits (145), Expect = 1e-09
Identities = 52/219 (23%), Positives = 104/219 (47%), Gaps = 21/219 (9%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERG 73
++E + + E+ ++++ E + ++L E+++ L ++ K E E + + + EK D+ E
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 74 MKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVA 133
+ + M +EKM QE Q+ E + D ++K + ++ + L EER
Sbjct: 470 G---QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 134 ESRARQLE---EELRTMDQALKSL-----MASEEEYSTKEDKYEEEIKLL---------- 175
+ +Q E EE +T +Q K+ M EE +E K EE +++
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 176 EEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEEN 214
EEK++E E + E + + E+ + + EE + +EE+
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Score = 60.1 bits (144), Expect = 2e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 8/179 (4%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIENRAMKD--EEKMELQEMQ 94
++L+++ LQ+KL+ E E + + K K + + + +E+M QE +
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 95 LKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL--- 151
L+E + + K +L EG++ EE+ E R R+ E+ELR ++ L
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 152 KSLMASEEEYSTKEDK---YEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 207
K L EE+ +E+K EE+++ EEK+ E R E+ + + E+ + D EE +
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Score = 58.2 bits (139), Expect = 6e-09
Identities = 50/218 (22%), Positives = 106/218 (48%), Gaps = 12/218 (5%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKK--QAEDRCKQLEE---EQQALQKKLKGTEDEVEKYS 61
+ Q L KE ++ + E ++K + E++ + EE +++ + ++ K E E + +
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEE----VARKLV 117
+ EK D+ E+ M E R + +E++ +E +++E K + + ++ EE K
Sbjct: 491 QEEKMRDQ-EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
+ E R EER E + R+ EE +R ++ ++ E K + EE+++ EE
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 178 KLKEAETR--AEFAERSVAKLEKTIDDLEETLASAKEE 213
K+ E E + + E + + E+ + + EE + +E+
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Score = 52.4 bits (124), Expect = 3e-07
Identities = 45/190 (23%), Positives = 86/190 (45%), Gaps = 25/190 (13%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIEN 79
++ E+ +K+ ++ K+L E+++ L+++ K E E E+ E E+ E E M+ E
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE-EQMQEQEEKMWEQEEKMREQEE 331
Query: 80 RAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAES---- 135
+ + EE++ QE Q++E + D + + E +L E + E+ E E
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 136 -----RARQLEEELRTMDQALKSLMASEEEY--------------STKEDKYEEE-IKLL 175
R +++ EE TM + + + EE KE +E+E ++
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 176 EEKLKEAETR 185
EEK+ E E +
Sbjct: 452 EEKIWEQEEK 461
Score = 49.7 bits (117), Expect = 2e-06
Identities = 49/215 (22%), Positives = 90/215 (41%), Gaps = 21/215 (9%)
Query: 14 DKENAIDRAEQAEADKKQA----EDRCKQLEEEQQALQKKLKGTE--DEVEKYSESEKAA 67
++E + EQ D+++ ++R ++ EE + +K + E E E+ E EK
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDR-----KYEEVARKLVILEGE 122
E E M+ E + K EE M QE + + + + E ++ K +E K+ E +
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 123 LERSEE----------RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEI 172
+ EE + ++ E + E+E + DQ K E + E E+E
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
Query: 173 KLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 207
++ E+K + E+ + EK D EE +
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Score = 48.9 bits (115), Expect = 4e-06
Identities = 43/209 (20%), Positives = 97/209 (46%), Gaps = 7/209 (3%)
Query: 12 KLDKENAI--DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV--EKYSESEKAA 67
+L K+NA ++ AE++K + + K+L+ + + + L + E+ E+
Sbjct: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
Query: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
E E+ ++ E + + EE++ QE +++E + +++ E ++L E EL
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR--- 300
Query: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
E+ ++ E + E+E + +Q K E+ + +E +E+E ++ E++ K +
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 188 FAERSVAKLEKTIDDLEETLASAKEENVE 216
E+ EK E+ +EE ++
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQ 389
Score = 37.4 bits (85), Expect = 0.011
Identities = 41/209 (19%), Positives = 89/209 (42%), Gaps = 29/209 (13%)
Query: 33 EDRCKQLEEEQQALQKKLKGTEDEVE----KYSESEKAADESERGMKVIENRAMKDEEKM 88
ED K + Q+AL+++++ + + + +E E A S+ + E+ + + + +
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 89 ------------ELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESR 136
ELQ L + +DR EE+ ++ L EL R+ E + +
Sbjct: 130 AGRLHHSWHFAGELQRA-LSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKK 188
Query: 137 ARQLEEELRTMDQALKSLMASEEEYSTKEDK------------YEEEIKLLEEKLKEAET 184
+L+E+LR + + + +E K ++ +EE+ EE+L+E E
Sbjct: 189 NAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 248
Query: 185 RAEFAERSVAKLEKTIDDLEETLASAKEE 213
+ E + + E+ + + E + +E+
Sbjct: 249 KIRKQEEKMWRQEERLREQEGKMREQEEK 277
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 68.6 bits (166), Expect = 4e-12
Identities = 52/199 (26%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESERGMKVIEN 79
++ ++ EA + E++ ++ EE+ + ++K+ E EK E EK +E +R +
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQE---QE 523
Query: 80 RAMKDEEKMELQE--MQLKEAKHIAEDSDRKYEEVA----RKLVILEGELERSEERAEVA 133
+ EEK+ QE + KE H E+ RK EE K+ E ++ EE+
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 134 ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSV 193
E + R+ EE++R ++ ++ +E K + EE++ EEK++E E + E +
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 194 AKLEKTIDDLEETLASAKE 212
+ EK I + EE + +E
Sbjct: 644 REQEKKIREQEEKIREQEE 662
Score = 68.2 bits (165), Expect = 6e-12
Identities = 41/201 (20%), Positives = 101/201 (50%)
Query: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEKAADESE 71
K ++ + R E+ ++++ + +++ E+++ ++K+ + + EK + E+ E E
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577
Query: 72 RGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 131
+ E + + EEK+ QE +++E + + ++ + K E K+ E +++ EE+
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR 637
Query: 132 VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAER 191
E + R+ E+++R ++ ++ +E K + EE++ EEK++E E + E
Sbjct: 638 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 192 SVAKLEKTIDDLEETLASAKE 212
+ + E + EE + +E
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQE 718
Score = 67.8 bits (164), Expect = 8e-12
Identities = 46/211 (21%), Positives = 107/211 (50%), Gaps = 6/211 (2%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEK 65
++ + + +KE I E+ ++++ ++ ++ +EE++ ++++ K E E + + + EK
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEK 485
Query: 66 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
++ E+ ++ E + + EEK+ QE +E K ++ + EE R+ + E+ R
Sbjct: 486 IREQEEK-IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE----QEEIWR 540
Query: 126 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 185
+E+ E + R+ EE++ ++ + E K + EE+I+ EEK++E E +
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 186 AEFAERSVAKLEKTIDDLEETLASAKEENVE 216
E + E+ + + EE + +E+ E
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Score = 67.4 bits (163), Expect = 1e-11
Identities = 44/206 (21%), Positives = 100/206 (48%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESE 64
K++ Q +E I E+ K++ ++ +++ ++++ + ++ + D+ EK E E
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577
Query: 65 KAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE 124
+ E ++ E + + EEK+ QE +E + + + K E K+ E ++
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR 637
Query: 125 RSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAET 184
R EE+ E + R+ EE++R ++ ++ E K + EE+++ EEK++ E
Sbjct: 638 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 185 RAEFAERSVAKLEKTIDDLEETLASA 210
+ E + + E+ + + +E L +A
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQEHLEAA 723
Score = 66.2 bits (160), Expect = 2e-11
Identities = 51/221 (23%), Positives = 106/221 (47%), Gaps = 6/221 (2%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEE--EQQALQKKLKGTEDEVEKYSE 62
K++ Q K+ ++ R EQ E ++Q E +Q E+ EQ+ ++++ K E E E + +
Sbjct: 471 KRQEQEAKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE-EMWRQ 528
Query: 63 SEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
EK ++ E + + + + EEK+ QE ++ + D + K E K+ E +
Sbjct: 529 EEKIREQEEIWRQ--KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK 586
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEA 182
+ EE+ E + R+ EE + ++ + E K + EE+++ EEK++E
Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 183 ETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
E + E + + E+ + + EE + +E+ E + + +
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Score = 65.9 bits (159), Expect = 3e-11
Identities = 50/229 (21%), Positives = 114/229 (49%), Gaps = 13/229 (5%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEE---EQQAL---QKKLKGTED 55
+ I+++ + + +E ++ + E +K+Q ++ + EE EQ+ + ++K+ E+
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Query: 56 EVEKYSES-----EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 110
++ K E EK D+ E+ ++ E + + EEK+ QE +++E + + + +
Sbjct: 551 KIRKQEEKMWRQEEKMHDQEEK-IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609
Query: 111 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 170
E K+ E ++ EE+ + E + R+ EE++R ++ ++ E + EE
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 669
Query: 171 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQ 219
++ EEK+ E E + + E + + E+ + + E L +EE ++ HQ
Sbjct: 670 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ-QEEKMQEHQ 717
Score = 63.5 bits (153), Expect = 1e-10
Identities = 48/225 (21%), Positives = 103/225 (45%), Gaps = 3/225 (1%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTED---EVE 58
+ I+++ + ++ +E + E+ +K E+ +Q +EE ++K++ E+ + E
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 59 KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI 118
K E E+ + E M E + EEK+ QE ++ + + + K E K+
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 119 LEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEK 178
E + EE+ E + + EE+++ ++ ++ E K + EE+I+ EE
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 179 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
++E E + E + + E+ + + EE + +E+ E L Q
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Score = 62.4 bits (150), Expect = 3e-10
Identities = 44/214 (20%), Positives = 106/214 (49%), Gaps = 9/214 (4%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE--- 62
++ + ++ +E ++ E+ +++ ++ K EEE++ Q+++ E+++ + E
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 63 SEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 122
++ E E ++ E + + EEKM QE +++E + + K E K+ E +
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 123 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL---EEKL 179
+ EE + E + + EE++ ++ ++ EE+ +E+K E+ K + EEK+
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQE---QEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 180 KEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
+E E + E + + E+ + + EE + +E+
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 61.2 bits (147), Expect = 7e-10
Identities = 59/237 (24%), Positives = 110/237 (46%), Gaps = 28/237 (11%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAE--------QAEAD----KKQAEDRCKQLEEEQQALQK 48
+++ K ++Q+ + + ++RA+ QAEAD + Q+ Q + E+ L
Sbjct: 294 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 353
Query: 49 KLKGTEDEV-----EKYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE 103
+L ++E EK E E+ E E ++ E + + EEKM QE + E E
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK----E 409
Query: 104 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMD--QALKSLMASEEEY 161
+ R+ EE+ + E ++ R EE E + R+LEE++ + + + EE+
Sbjct: 410 EKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466
Query: 162 STKEDKYEEEIKL--LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 216
+E + E+E K+ EEK++E E + E + + E+ I + E+ K + E
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Score = 60.8 bits (146), Expect = 9e-10
Identities = 56/220 (25%), Positives = 107/220 (48%), Gaps = 30/220 (13%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTED---EVEKYSE 62
++ + + +KE + R E+ +K E++ ++LEE+ Q+K++ E+ E EK E
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHE-QEKIREQEEKRQEEEKIRE 468
Query: 63 SEKAADES------ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKL 116
EK ++ E ++ E + + EEKM QE ++ E + I E+ R+ +E
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE----- 523
Query: 117 VILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY---EEEIK 173
E+ R EE+ E RQ +E++ ++ ++ EE+ +E+K EE+I+
Sbjct: 524 -----EMWRQEEKIREQEEIWRQ-KEKIHEQEEKIRK---QEEKMWRQEEKMHDQEEKIR 574
Query: 174 LLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
EEK+ E + E + + E+ I + EE +E+
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Score = 60.1 bits (144), Expect = 2e-09
Identities = 55/246 (22%), Positives = 115/246 (46%), Gaps = 34/246 (13%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKK-QAEDRCKQLEEEQQALQKKLKGTEDEV-- 57
+ ++ K+Q ++++ +R Q + +K + E++ ++ EE+ Q ++K++ E+++
Sbjct: 335 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 58 --EKYSESEKAADESERGMKVIENRAMKDEEKM---------------ELQEMQLKEAKH 100
EK E+ E E M+ E + EEKM EL+E ++ K
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453
Query: 101 IAEDSDRKYEEVAR---KLVILEGELERSEERAEVAESRARQLEEELRTMDQAL--KSLM 155
++ R+ EE R K E ++ R EE+ E + R+ EE++ ++ + + +
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 156 ASEEEYSTKEDKYEEEIKLLE--------EKLKEAETRAEFAERSVAKLEKTIDDLEETL 207
EE+ +E+ + +E K+ E EK+ E E + E + + E+ + D EE +
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Query: 208 ASAKEE 213
+E+
Sbjct: 574 REQEEK 579
Score = 56.2 bits (134), Expect = 2e-08
Identities = 53/221 (23%), Positives = 106/221 (47%), Gaps = 32/221 (14%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESEK 65
++ + + +KE + R E+ +K E++ ++ EE ++K++ E EK E EK
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELE---EKMHEQEK 452
Query: 66 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 125
++ E+ E ++++EK + QE ++ E+ R+ EE R+ E ++ R
Sbjct: 453 IREQEEKRQ---EEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQ---EEKMWR 502
Query: 126 SEER----AEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL------- 174
EE+ ++ E RQ +EE+ ++ ++ EE + KE +E+E K+
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE---QEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 175 --LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 213
EEK+ + E + E V + E+ I + EE + +E+
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Score = 46.6 bits (109), Expect = 2e-05
Identities = 52/223 (23%), Positives = 111/223 (49%), Gaps = 22/223 (9%)
Query: 19 IDRAEQAEADKKQAEDR-CKQLEEEQQALQKKLKG---TEDEV-EKYSESEKA-----AD 68
+++A A A +K+ DR ++L +E+ AL +L T++E+ EK ++ ++ ++
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 297
Query: 69 ESERGMKVIENRAMKDEEKMELQEMQLK-EAKHIAEDSDRKYEEVARKLV--ILEGEL-- 123
+SE + V E + + K+ L + QL+ EA H+ ++ + V+ KL + E EL
Sbjct: 298 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE----LQSVSAKLQAQVEENELWN 353
Query: 124 ---ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 180
++ EE+ E + ++ EE+++ ++ ++ E K + EE + EEK++
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 413
Query: 181 EAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 223
E E + + E+ + + EE + +E+ E + +Q
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 456
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.120 0.288
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,125,895
Number of Sequences: 37866
Number of extensions: 350761
Number of successful extensions: 17278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 943
Number of HSP's successfully gapped in prelim test: 1027
Number of HSP's that attempted gapping in prelim test: 3704
Number of HSP's gapped (non-prelim): 7657
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.