Guide to the Human Genome
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Search of human proteins with 11545875

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11545875 GDNF family receptor alpha 4 isoform a precursor
[Homo sapiens]
         (269 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Ho...   559   e-160
gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Ho...   467   e-132
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei...   191   7e-49
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein...   191   7e-49
gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ...   191   7e-49
gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap...   177   9e-45
gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap...   151   5e-37
gi|148231468 GDNF family receptor alpha like [Homo sapiens]            64   2e-10
gi|13376335 hypothetical protein LOC79946 [Homo sapiens]               41   0.001
gi|239757960 PREDICTED: hypothetical protein [Homo sapiens]            34   0.15 
gi|21264602 laminin alpha 5 [Homo sapiens]                             34   0.15 
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa...    34   0.15 
gi|134244285 Notch homolog 3 [Homo sapiens]                            33   0.26 
gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens]           33   0.26 
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                  33   0.34 
gi|157909822 pragmin [Homo sapiens]                                    33   0.34 
gi|167466169 growth arrest-specific 1 [Homo sapiens]                   32   0.44 
gi|134031945 SCO-spondin [Homo sapiens]                                32   0.44 
gi|115511036 alpha-kinase 3 [Homo sapiens]                             32   0.76 
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap...    31   0.99 
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s...    31   0.99 
gi|169218002 PREDICTED: hypothetical protein [Homo sapiens]            30   1.7  
gi|239742701 PREDICTED: hypothetical protein XP_002342609 [Homo ...    30   1.7  
gi|169163057 PREDICTED: hypothetical protein [Homo sapiens]            30   1.7  
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    30   1.7  
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                      30   1.7  
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                      30   1.7  
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]    30   1.7  
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]              30   1.7  
gi|239747084 PREDICTED: hypothetical protein XP_002343912 [Homo ...    30   2.2  

>gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Homo
           sapiens]
          Length = 269

 Score =  559 bits (1441), Expect = e-160
 Identities = 269/269 (100%), Positives = 269/269 (100%)

Query: 1   MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP 60
           MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP
Sbjct: 1   MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP 60

Query: 61  RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP 120
           RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP
Sbjct: 61  RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP 120

Query: 121 LNFCERSRVCRPRLLAFQVSCTPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVS 180
           LNFCERSRVCRPRLLAFQVSCTPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVS
Sbjct: 121 LNFCERSRVCRPRLLAFQVSCTPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVS 180

Query: 181 ARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHS 240
           ARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHS
Sbjct: 181 ARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHS 240

Query: 241 LLQVSSTGRALERRSLLSILPVLALPALL 269
           LLQVSSTGRALERRSLLSILPVLALPALL
Sbjct: 241 LLQVSSTGRALERRSLLSILPVLALPALL 269


>gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Homo
           sapiens]
          Length = 299

 Score =  467 bits (1202), Expect = e-132
 Identities = 242/299 (80%), Positives = 245/299 (81%), Gaps = 30/299 (10%)

Query: 1   MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP 60
           MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP
Sbjct: 1   MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP 60

Query: 61  RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP 120
           RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP
Sbjct: 61  RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP 120

Query: 121 LNFCERSRVCRPRLLA------FQVSCTPAPSAP---------DGCLLDQGARCLRAYAG 165
           LNFCERSRVCR    A      +    +PA   P          G +     R  R  AG
Sbjct: 121 LNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAG 180

Query: 166 L---------------VGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNR 210
                            GTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNR
Sbjct: 181 PGRPLPARLRGPRGVPAGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNR 240

Query: 211 CLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL 269
           CLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL
Sbjct: 241 CLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL 299


>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  191 bits (484), Expect = 7e-49
 Identities = 91/208 (43%), Positives = 121/208 (58%), Gaps = 7/208 (3%)

Query: 23  GNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHA 82
           GN C+DAA+AC  D  C++ RS Y+  C    +   C R +C +ALR+FF + P   ++ 
Sbjct: 146 GNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYG 205

Query: 83  LLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCT 142
           +LFC C   AC ERRRQT VP C++       P+CL   + C+ + +CR RL  F  +C 
Sbjct: 206 MLFCSCRDIACTERRRQTIVPVCSYEER--EKPNCLNLQDSCKTNYICRSRLADFFTNCQ 263

Query: 143 PAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAF 202
           P   +   CL +  A CL AY+GL+GT +TPNY+D+ S  VAPWCDC  SGN  E+C  F
Sbjct: 264 PESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKF 323

Query: 203 RGLFTRNRCLDGAIQAFASG-----WPP 225
              F  N CL  AIQAF +G     W P
Sbjct: 324 LNFFKDNTCLKNAIQAFGNGSDVTVWQP 351


>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  191 bits (484), Expect = 7e-49
 Identities = 91/208 (43%), Positives = 121/208 (58%), Gaps = 7/208 (3%)

Query: 23  GNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHA 82
           GN C+DAA+AC  D  C++ RS Y+  C    +   C R +C +ALR+FF + P   ++ 
Sbjct: 146 GNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYG 205

Query: 83  LLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCT 142
           +LFC C   AC ERRRQT VP C++       P+CL   + C+ + +CR RL  F  +C 
Sbjct: 206 MLFCSCRDIACTERRRQTIVPVCSYEER--EKPNCLNLQDSCKTNYICRSRLADFFTNCQ 263

Query: 143 PAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAF 202
           P   +   CL +  A CL AY+GL+GT +TPNY+D+ S  VAPWCDC  SGN  E+C  F
Sbjct: 264 PESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKF 323

Query: 203 RGLFTRNRCLDGAIQAFASG-----WPP 225
              F  N CL  AIQAF +G     W P
Sbjct: 324 LNFFKDNTCLKNAIQAFGNGSDVTVWQP 351


>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
           [Homo sapiens]
          Length = 465

 Score =  191 bits (484), Expect = 7e-49
 Identities = 91/208 (43%), Positives = 121/208 (58%), Gaps = 7/208 (3%)

Query: 23  GNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHA 82
           GN C+DAA+AC  D  C++ RS Y+  C    +   C R +C +ALR+FF + P   ++ 
Sbjct: 151 GNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYG 210

Query: 83  LLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCT 142
           +LFC C   AC ERRRQT VP C++       P+CL   + C+ + +CR RL  F  +C 
Sbjct: 211 MLFCSCRDIACTERRRQTIVPVCSYEER--EKPNCLNLQDSCKTNYICRSRLADFFTNCQ 268

Query: 143 PAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAF 202
           P   +   CL +  A CL AY+GL+GT +TPNY+D+ S  VAPWCDC  SGN  E+C  F
Sbjct: 269 PESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKF 328

Query: 203 RGLFTRNRCLDGAIQAFASG-----WPP 225
              F  N CL  AIQAF +G     W P
Sbjct: 329 LNFFKDNTCLKNAIQAFGNGSDVTVWQP 356


>gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo
           sapiens]
          Length = 464

 Score =  177 bits (449), Expect = 9e-45
 Identities = 88/206 (42%), Positives = 117/206 (56%), Gaps = 5/206 (2%)

Query: 20  SVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGG-CPRARCRRALRRFFARGPPA 78
           S   N C+DAA+AC  +  C++LRS Y++ C    +    C R +C +ALR+FF R P  
Sbjct: 155 SAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSE 214

Query: 79  LTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQ 138
            T+ +LFC C   ACAERRRQT +PSC++       P+CL+    C    +CR RL  F 
Sbjct: 215 YTYRMLFCSCQDQACAERRRQTILPSCSYE--DKEKPNCLDLRGVCRTDHLCRSRLADFH 272

Query: 139 VSCTPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDN--VSARVAPWCDCGASGNRR 196
            +C  +      C  D    CL +YAG++G  +TPNYVD+      V+PWC C  SGN  
Sbjct: 273 ANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332

Query: 197 EDCEAFRGLFTRNRCLDGAIQAFASG 222
           E+CE F   FT N CL  AIQAF +G
Sbjct: 333 EECEKFLRDFTENPCLRNAIQAFGNG 358


>gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
           sapiens]
          Length = 400

 Score =  151 bits (382), Expect = 5e-37
 Identities = 86/209 (41%), Positives = 104/209 (49%), Gaps = 19/209 (9%)

Query: 26  CVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLF 85
           C+  A  CT + +C RLR  Y   C G      C R  C R L  FF +        LL 
Sbjct: 162 CLKFAMLCTLNDKCDRLRKAYGEACSGPH----CQRHVCLRQLLTFFEKAAEPHAQGLLL 217

Query: 86  CPCA--GPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCTP 143
           CPCA     C ERRR T  P+CA     P  P+CLE    C    +CR RL+ FQ  C P
Sbjct: 218 CPCAPNDRGCGERRRNTIAPNCALP---PVAPNCLELRRLCFSDPLCRSRLVDFQTHCHP 274

Query: 144 APSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFR 203
                 G    + +RCLRAY GL+GTA+TPN+V NV+  VA  C C  SGN +E+CE   
Sbjct: 275 MDIL--GTCATEQSRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEECEMLE 332

Query: 204 GLFTRNRCLDGAI--------QAFASGWP 224
           G F+ N CL  AI        Q F+  WP
Sbjct: 333 GFFSHNPCLTEAIAAKMRFHSQLFSQDWP 361


>gi|148231468 GDNF family receptor alpha like [Homo sapiens]
          Length = 394

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 48/196 (24%), Positives = 76/196 (38%), Gaps = 16/196 (8%)

Query: 26  CVDAAEACTADARCQRLRSEYVAQCLGRAAQGG-CPRARCRRALRRFFARGPPALTHALL 84
           C++ AEAC  D  C    + Y+  C   +A G  C   +C+ A+R F+   P  +   L 
Sbjct: 131 CLEVAEACVGDVVCNAQLASYLKAC---SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187

Query: 85  FCPCAGP--ACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSC- 141
           FC CA     C + +      +CA +     PP+CL  +  C+   +CR     FQ  C 
Sbjct: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMV--PPPTCLSVIRSCQNDELCRRHYRTFQSKCW 245

Query: 142 ---TPAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRRED 198
              T      + C+     + L         A    Y+D +   +   C C       E 
Sbjct: 246 QRVTRKCHEDENCISTLSKQDLTCSGSDDCKAA---YIDILGTVLQVQCTCRTITQSEES 302

Query: 199 -CEAFRGLFTRNRCLD 213
            C+ F+ +  R  C +
Sbjct: 303 LCKIFQHMLHRKSCFN 318


>gi|13376335 hypothetical protein LOC79946 [Homo sapiens]
          Length = 257

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 39/119 (32%), Positives = 50/119 (42%), Gaps = 16/119 (13%)

Query: 29  AAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLFCPC 88
           A    + D RC+R R    A   GR A G C +  C  A   + ARG P  ++      C
Sbjct: 135 APPPASRDCRCRRPRRWPRAGRRGRRA-GAC-KPSCAGAA--WSARGAPLCSYRT---SC 187

Query: 89  AGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCTPAPSA 147
           AG +C  R   T  P+CA   P  A  SC      C R R C     A+  +C   P+A
Sbjct: 188 AG-SCGARTAPTPAPTCA--SPSAAASSC------CRRRRACSSPTTAWSGACGAGPTA 237


>gi|239757960 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 292

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 5/101 (4%)

Query: 53  RAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPG- 111
           + A  G P +  R   RR     PP    +     CAG +C         PS A  GPG 
Sbjct: 23  QVAPPGGPXSLARTHSRRHPDHAPPPGRPSCSRPLCAGSSCLATPEPARAPSIAEPGPGI 82

Query: 112 ---PAPPSCLEPLNFCERSRVCRPRLLAFQVSC-TPAPSAP 148
               A P  L     C  +R   P L   +  C  P P+AP
Sbjct: 83  PVAAAKPGVLPGGGGCTGARTENPPLSPTRGDCRVPVPAAP 123


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 48/166 (28%), Positives = 57/166 (34%), Gaps = 42/166 (25%)

Query: 23  GNRCVDAAEACTA------------DARCQRLRSEYVAQCLGRAAQGGCPRARCRRALR- 69
           G RC   AE  T             D R Q L +  +  C   AA  G     CR+  R 
Sbjct: 455 GERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAA--GTQGNACRKDPRV 512

Query: 70  -RFFARGPPALTHALLFCP-CAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERS 127
            R   +     TH  L  P   GP C           C  S PG A   C      C R 
Sbjct: 513 GRCLCKPNFQGTHCELCAPGFYGPGCQP---------CQCSSPGVADDRCDPDTGQC-RC 562

Query: 128 RV---------CRPRLLAFQV----SCTPAPSAPDGCLLDQGARCL 160
           RV         C P    F +     C+PA + P+GC  D+  RCL
Sbjct: 563 RVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGC--DEAGRCL 606


>gi|38348414 von Willebrand factor C domain containing 2 [Homo
           sapiens]
          Length = 325

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 11/63 (17%)

Query: 67  ALRRFFARGPPALTHALLFCPCA----GPACAERRRQTFVPSCAFSGPGPAPPSCLEPLN 122
           A+   FA GP A       CPC     GP CA+       P C         P C E  N
Sbjct: 164 AIGEKFAPGPSA-------CPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKN 216

Query: 123 FCE 125
           +CE
Sbjct: 217 YCE 219


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 33.1 bits (74), Expect = 0.26
 Identities = 36/158 (22%), Positives = 48/158 (30%), Gaps = 38/158 (24%)

Query: 23  GNRCVDAAEACTAD-----ARCQRLRSEYVAQC------------LGRAAQGGCPRARCR 65
           G RC    + C +       +C  L  +Y+ +C            +   A   C    CR
Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635

Query: 66  RALRRFFARGPPALTHALL---FCPCAGPACAERRRQTFVPSCA--------FSGPGPAP 114
             + R+     P  T  L       CA   C E        SC            PG  P
Sbjct: 636 DGINRYDCVCQPGFTGPLCNVEINECASSPCGEGG------SCVDGENGFRCLCPPGSLP 689

Query: 115 PSCLEPLNFCERS----RVCRPRLLAFQVSCTPAPSAP 148
           P CL P + C        +C      F+  C P  S P
Sbjct: 690 PLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGP 727


>gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens]
          Length = 1180

 Score = 33.1 bits (74), Expect = 0.26
 Identities = 20/59 (33%), Positives = 26/59 (44%)

Query: 16   GSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFAR 74
            G  ++ G N+      A   DAR +R R  +V+   G AA  G P  R RR   R   R
Sbjct: 1104 GVGTAGGANKAAATRAAQARDARSERPRRAFVSGGAGAAAAAGRPERRMRRPAARIGER 1162


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score = 32.7 bits (73), Expect = 0.34
 Identities = 39/168 (23%), Positives = 54/168 (32%), Gaps = 17/168 (10%)

Query: 27   VDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLFC 86
            VD +EA      C  +  E + +CLG         A C R    F+     A       C
Sbjct: 855  VDPSEA----GHCDSVTGECL-KCLGNT-----DGAHCERCADGFYGDAVTAKNCRACEC 904

Query: 87   PCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCTPAPS 146
               G   A    +T +  C  +  G     CL      +    CRP       +C+ A S
Sbjct: 905  HVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRP------CNCSVAGS 958

Query: 147  APDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGN 194
              DGC  +    C+   AG         +         P CDC  + N
Sbjct: 959  VSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTP-CDCPHTQN 1005


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 32.7 bits (73), Expect = 0.34
 Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 1/33 (3%)

Query: 88  CAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP 120
           C+GPA  E+R  +F   C   GP  A PSCL P
Sbjct: 294 CSGPAEQEKRGPSFPKECCSQGP-TAHPSCLGP 325


>gi|167466169 growth arrest-specific 1 [Homo sapiens]
          Length = 345

 Score = 32.3 bits (72), Expect = 0.44
 Identities = 29/104 (27%), Positives = 38/104 (36%), Gaps = 8/104 (7%)

Query: 16  GSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARG 75
           G   + G   C +A   C  D+RC    S Y+  C G+   G      CR  +    A  
Sbjct: 156 GGPGAGGVMGCTEARRRCDRDSRCNLALSRYLTYC-GKVFNGLRCTDECRTVIEDMLAMP 214

Query: 76  PPALTHALLFCPCAG---PACAERRRQTFVPSCAFSGPGPAPPS 116
             AL   L  C C G   P C E  ++     C  +  G  P S
Sbjct: 215 KAAL---LNDCVCDGLERPIC-ESVKENMARLCFGAELGNGPGS 254


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 32.3 bits (72), Expect = 0.44
 Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 9/76 (11%)

Query: 87   PCAGPA-CAERRRQTFVPSCAFSGPGPAPPSCLEP------LNFCERSRVCRPRLLAFQV 139
            PC+G   C   R       C      P PPSCL+P         C     C P LL    
Sbjct: 2608 PCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDT 2667

Query: 140  SCTPAPSAPDGCLLDQ 155
             C P    P  CL+ +
Sbjct: 2668 RCLPLSECP--CLVGE 2681



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 24/80 (30%), Positives = 25/80 (31%), Gaps = 8/80 (10%)

Query: 75   GPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCL------EPLNFCERSR 128
            GP + T      PC    C E         C   G GP P  CL      E   FC    
Sbjct: 2869 GPHSQTRDCNTQPCTAQ-CPENMLFRSAEQCHQEG-GPCPRLCLTQGPGIECTGFCAPGC 2926

Query: 129  VCRPRLLAFQVSCTPAPSAP 148
             C P L     SC P    P
Sbjct: 2927 TCPPGLFLHNASCLPRSQCP 2946


>gi|115511036 alpha-kinase 3 [Homo sapiens]
          Length = 1907

 Score = 31.6 bits (70), Expect = 0.76
 Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 10/96 (10%)

Query: 16   GSASSVGGNRCVDAAEACTADAR-------CQRLRSEYVAQCLGRAAQGGCPRARCRRAL 68
            GS   VGG RC     +   +A+       C +        C+    QGGCP A   + +
Sbjct: 1010 GSVEQVGGERCRGPQSSGPVEAKQEDSPFQCPKEERPGGVPCMD---QGGCPLAGLSQEV 1066

Query: 69   RRFFARGPPALTHALLFCPCAGPACAERRRQTFVPS 104
                +     LT +    PC+ P        TF+PS
Sbjct: 1067 PTMPSLPGTGLTASPKAGPCSTPTSQHGSTATFLPS 1102


>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo
           sapiens]
          Length = 254

 Score = 31.2 bits (69), Expect = 0.99
 Identities = 40/148 (27%), Positives = 51/148 (34%), Gaps = 17/148 (11%)

Query: 54  AAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPA 113
           AA+    R     A  R  A GPPA   A+++   AGP+ A          CA +   PA
Sbjct: 9   AAKTSVRRPAAAPAAVRPPAAGPPAAAPAVVYPAAAGPSAAS--------LCAANPLVPA 60

Query: 114 PPSCLEPLNFCERSRVCRPRLLAFQVSCTPAPSAPDGCLLDQGARCLRAYAGLVGTAVTP 173
           P +   P        V  P   A  V C PA + P    L        A A +   A T 
Sbjct: 61  PAAVRPP--------VAGPPATAPAVVC-PAAAGPSAASLRAANPLAVAPAAVRRPAATL 111

Query: 174 NYVDNVSARVAPWCDCGASGNRREDCEA 201
                 +   A  C   AS +    C A
Sbjct: 112 GAASPAAVAPAAVCPAAASPSAASLCAA 139


>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
           sapiens]
          Length = 414

 Score = 31.2 bits (69), Expect = 0.99
 Identities = 35/126 (27%), Positives = 46/126 (36%), Gaps = 24/126 (19%)

Query: 16  GSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQG----GCPRARCRRALRRF 71
           G+   VGG  C D A     DA     ++       GR ++     G P     R+LRR 
Sbjct: 306 GNGGGVGGGACGDLASEIREDAVAPGCKAS------GRGSRVTHLLGYPTQNVSRSLRRK 359

Query: 72  FARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGP--APPSCLEPLNFCERSRV 129
           +A  PP         PC GP        T   +C  +GP P        EP +  E    
Sbjct: 360 YA--PP---------PCGGPEDVALAPCTAAAACE-AGPSPVYVKVKSAEPADCAEGPVQ 407

Query: 130 CRPRLL 135
           C+  LL
Sbjct: 408 CKNGLL 413


>gi|169218002 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 218

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 7/101 (6%)

Query: 53  RAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGP 112
           + A  G P +  R   RR     PP    +     CAG +C         PS A  GPG 
Sbjct: 16  QVAPPGGPSSLARTHSRRHPDHAPPPGRPSCSRPLCAGSSCLATPEPARAPSIAEPGPG- 74

Query: 113 APPSCLEPL-----NFCERSRVCRPRLLAFQVSC-TPAPSA 147
            P + ++P+       C  +R   P L   +  C  P P+A
Sbjct: 75  IPVAAIKPVILPGGGGCTGARTENPPLSPTRGDCRVPVPAA 115


>gi|239742701 PREDICTED: hypothetical protein XP_002342609 [Homo
           sapiens]
          Length = 192

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)

Query: 86  CPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLN 122
           C     A A  RR ++ P CA     P+PPS L PLN
Sbjct: 115 CQLTDAAVATTRRHSWSPPCA-----PSPPSGLHPLN 146


>gi|169163057 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 7/101 (6%)

Query: 53  RAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGP 112
           + A  G P +  R   RR     PP    +     CAG +C         PS A  GPG 
Sbjct: 43  QVAPPGGPSSLARTHSRRHPDHAPPPGRPSCSRPLCAGSSCLATPEPARAPSIAEPGPG- 101

Query: 113 APPSCLEPL-----NFCERSRVCRPRLLAFQVSC-TPAPSA 147
            P + ++P+       C  +R   P L   +  C  P P+A
Sbjct: 102 IPVAAIKPVILPGGGGCTGARTENPPLSPTRGDCRVPVPAA 142


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
           sapiens]
          Length = 1751

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 8/56 (14%)

Query: 102 VPSCAFSGPGPAPPSCLEPLNFCERSR-VCRPRLLA--FQVSCTPAPSAPDG-CLL 153
           VP C  S P PAPP C +   FCE  +  C  RL      V+C   P+  DG C+L
Sbjct: 394 VPPCG-SVPPPAPPPCCQ---FCEALQDACWSRLGGGRLPVACASLPTQEDGYCVL 445


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 19/73 (26%)

Query: 47   VAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCA 106
            V+ C+G  A    P  +  + LR F   GPP             P C ER R+TFV    
Sbjct: 1195 VSLCVGCFA----PSEKFVKYLRNFIHGGPPGYA----------PYCEERLRRTFV---- 1236

Query: 107  FSGPGPAPPSCLE 119
             +G    PPS LE
Sbjct: 1237 -NGTRTQPPSWLE 1248


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 19/73 (26%)

Query: 47   VAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCA 106
            V+ C+G  A    P  +  + LR F   GPP             P C ER R+TFV    
Sbjct: 1195 VSLCVGCFA----PSEKFVKYLRNFIHGGPPGYA----------PYCEERLRRTFV---- 1236

Query: 107  FSGPGPAPPSCLE 119
             +G    PPS LE
Sbjct: 1237 -NGTRTQPPSWLE 1248


>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
          Length = 814

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 33/123 (26%), Positives = 38/123 (30%), Gaps = 18/123 (14%)

Query: 42  LRSEYVAQCLGRAAQGGCPRARCRRALRR--FFARGPPALTHALLFCPCAGPACAERRRQ 99
           L  E   QC    A  GCPR     A  +  F   G P        C C   + + +R  
Sbjct: 648 LPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRR-----CLCLDGSVSCQRLP 702

Query: 100 TFVPSCAFSGPGPAPPSC----LEPLNFCERSRVCRPRLLAF-------QVSCTPAPSAP 148
                CA    GP  PSC     +   F    R   P             VSC P   AP
Sbjct: 703 CPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 762

Query: 149 DGC 151
             C
Sbjct: 763 ALC 765


>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
          Length = 1729

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 12/59 (20%)

Query: 108 SGPGPAPPSCLEPLNFCERSRVCRPRLL------AFQVSCTPA--PSAPDGCLLDQGAR 158
           SG GP  P    P    ++S  C  +LL      A Q S  PA  PSAP   L D+G+R
Sbjct: 295 SGSGPGSPHLHPP----DKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSR 349


>gi|239747084 PREDICTED: hypothetical protein XP_002343912 [Homo
           sapiens]
          Length = 313

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 89  AGPACAERRRQTFVPSCAFSGPG--PAPP----SCLEPLNFCERSRVCR---PRLLAFQV 139
           A P  A R R   VP    + PG  P+PP         LNF  R + CR     LLA QV
Sbjct: 101 AEPGSARRNRPARVPDSPAARPGAAPSPPERWADFAVNLNFPSRLQPCRRTSAPLLAPQV 160

Query: 140 SCTPAPSAPDGCLLDQGARCLRAY 163
           +    P +P G L   G+     Y
Sbjct: 161 ARPAFPKSP-GSLRSSGSLATLTY 183


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,446,845
Number of Sequences: 37866
Number of extensions: 670449
Number of successful extensions: 2591
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2509
Number of HSP's gapped (non-prelim): 110
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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