Guide to the Human Genome
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Search of human proteins with 11545873

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11545873 secreted modular calcium-binding protein 1 isoform
2 [Homo sapiens]
         (434 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11545873 secreted modular calcium-binding protein 1 isoform 2...   911   0.0  
gi|78190498 secreted modular calcium-binding protein 1 isoform 1...   907   0.0  
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]    480   e-135
gi|144953895 nidogen 2 precursor [Homo sapiens]                        83   4e-16
gi|55770862 thyroglobulin [Homo sapiens]                               75   1e-13
gi|115298674 nidogen 1 precursor [Homo sapiens]                        65   2e-10
gi|12383051 transmembrane protein with EGF-like and two follista...    54   2e-07
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo...    53   5e-07
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo...    50   3e-06
gi|54873613 agrin [Homo sapiens]                                       48   2e-05
gi|93141003 testican 3 isoform 1 [Homo sapiens]                        47   3e-05
gi|93141001 testican 3 isoform 2 [Homo sapiens]                        47   3e-05
gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]      46   8e-05
gi|68448544 CD74 antigen isoform a [Homo sapiens]                      46   8e-05
gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]    45   1e-04
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]         45   1e-04
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]         45   1e-04
gi|190194423 SPARC-like 1 [Homo sapiens]                               45   1e-04
gi|190341024 SPARC-like 1 [Homo sapiens]                               45   1e-04
gi|29568105 transmembrane protein with EGF-like and two follista...    45   1e-04
gi|4504615 insulin-like growth factor binding protein 1 precurso...    44   4e-04
gi|62243068 insulin-like growth factor binding protein 3 isoform...    43   5e-04
gi|62243248 insulin-like growth factor binding protein 3 isoform...    43   5e-04
gi|62243290 insulin-like growth factor binding protein 4 precurs...    42   0.001
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ...    40   0.004
gi|10834982 insulin-like growth factor binding protein 5 [Homo s...    39   0.007
gi|11321593 insulin-like growth factor binding protein 6 [Homo s...    39   0.009
gi|189242612 complement component 6 precursor [Homo sapiens]           39   0.009
gi|169636415 complement component 6 precursor [Homo sapiens]           39   0.009
gi|54792136 follistatin-like 4 [Homo sapiens]                          39   0.009

>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
           [Homo sapiens]
          Length = 434

 Score =  911 bits (2355), Expect = 0.0
 Identities = 434/434 (100%), Positives = 434/434 (100%)

Query: 1   MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDG 60
           MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDG
Sbjct: 1   MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDG 60

Query: 61  RSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120
           RSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGE
Sbjct: 61  RSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120

Query: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSK 180
           DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSK
Sbjct: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSK 180

Query: 181 PTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQ 240
           PTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQ
Sbjct: 181 PTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQ 240

Query: 241 NPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKT 300
           NPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKT
Sbjct: 241 NPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKT 300

Query: 301 TEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE 360
           TEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE
Sbjct: 301 TEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE 360

Query: 361 ERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPE 420
           ERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPE
Sbjct: 361 ERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPE 420

Query: 421 LKGCLGVSKEGRLV 434
           LKGCLGVSKEGRLV
Sbjct: 421 LKGCLGVSKEGRLV 434


>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 435

 Score =  907 bits (2343), Expect = 0.0
 Identities = 434/435 (99%), Positives = 434/435 (99%), Gaps = 1/435 (0%)

Query: 1   MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDG 60
           MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDG
Sbjct: 1   MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDG 60

Query: 61  RSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120
           RSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGE
Sbjct: 61  RSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120

Query: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSK 180
           DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSK
Sbjct: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSK 180

Query: 181 PTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQ 240
           PTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQ
Sbjct: 181 PTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQ 240

Query: 241 NPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKT 300
           NPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKT
Sbjct: 241 NPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKT 300

Query: 301 TEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE 360
           TEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE
Sbjct: 301 TEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE 360

Query: 361 ERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPE 420
           ERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPE
Sbjct: 361 ERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPE 420

Query: 421 LKGCLGVSKE-GRLV 434
           LKGCLGVSKE GRLV
Sbjct: 421 LKGCLGVSKEVGRLV 435


>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
          Length = 457

 Score =  480 bits (1235), Expect = e-135
 Identities = 227/406 (55%), Positives = 294/406 (72%), Gaps = 24/406 (5%)

Query: 38  DRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRL 97
           D+D  C+L C+ +  KP+CASDGR++ S CE+QRAKC+DP L + +RG CKD   S+C  
Sbjct: 35  DKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDV--SRCVA 92

Query: 98  ERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPV 157
           ER    EQA+K  + VF+PEC +DG+++QVQCH+YTGYCWCVTP+G+PISG++V +KTP 
Sbjct: 93  ERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPR 152

Query: 158 CSGSVTDKPLSQGNSGR-----------KDDGSKPTPTMETQPVFDGDEITA--PTLWIK 204
           C GSV +K   +  +G+            DD +   P +ETQP  D ++I +  PTLW +
Sbjct: 153 CPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAA--APALETQPQGDEEDIASRYPTLWTE 210

Query: 205 HLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQ 264
            +  + +K N  ++       SCDQE QSALEEA+Q   + +VIPECA GGLYKPVQCH 
Sbjct: 211 QVKSRQNKTNKNSVS------SCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHP 264

Query: 265 STGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFI 324
           STGYCWCVLVDTGRP+PGTSTRY  P C++ ARA   +A D +K R+L GCP  KK EF+
Sbjct: 265 STGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKGRQLQGCPGAKKHEFL 324

Query: 325 TSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREM 384
           TS+LDAL+TDMV A +  + +  GR SEPDPSHTLEERVVHWYF  LD NSS DI K+E+
Sbjct: 325 TSVLDALSTDMVHAASDPS-SSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEI 383

Query: 385 KPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKE 430
           KPFKR+++KK+KPKKC ++F +YCD+N DK IS+ EL GCLGV+KE
Sbjct: 384 KPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELMGCLGVAKE 429


>gi|144953895 nidogen 2 precursor [Homo sapiens]
          Length = 1375

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 55/201 (27%), Positives = 79/201 (39%), Gaps = 59/201 (29%)

Query: 95   CRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ-- 152
            C  ++  A  Q   P     +P+C E G+F  +QCH  TG+CWCV PDG  + G+     
Sbjct: 940  CEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPG 999

Query: 153  NKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSK 212
            +  P C                   G  P PT              PT+           
Sbjct: 1000 STPPHC-------------------GPSPEPTQR-----------PPTI----------- 1018

Query: 213  LNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCV 272
                          C++ R++ LE     PR+   +P+C   G + P+QCH  + +CWCV
Sbjct: 1019 --------------CERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCV 1064

Query: 273  LVDTGRPLPGT-STRYVMPSC 292
              D GR + GT S     P+C
Sbjct: 1065 DKD-GREVQGTRSQPGTTPAC 1084



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 95   CRLERAQALEQ-AKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ- 152
            C   R   LE     P++  +VP+C + G F  +QCH  + +CWCV  DG+ + G+  Q 
Sbjct: 1019 CERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQP 1078

Query: 153  NKTPVCSGSV 162
              TP C  +V
Sbjct: 1079 GTTPACIPTV 1088


>gi|55770862 thyroglobulin [Homo sapiens]
          Length = 2768

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 17/192 (8%)

Query: 114  FVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPV------CSGSVTDKPL 167
            ++P+C   GS+  VQCH  TG+CWCV   G  I GS       +      C  S T   L
Sbjct: 1027 YMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKSRTSGLL 1086

Query: 168  SQGNSGRKDDGSKPTPTMETQPVFDGD----EITAPTLWIKHLVIKDSKLNNTNIRNSEK 223
            S     R  +   P        +  G+    + +    W       +     ++  +S +
Sbjct: 1087 SSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPASGEELRPGSS--SSAQ 1144

Query: 224  VYSCDQERQSALEEAQQNPREGIVIPEC-APGGLYKPVQCHQSTGYCWCVLVDTGRPLPG 282
              S     +S +   + +P     +P C A  G + PVQC Q+ G CWCV+ D+G  +PG
Sbjct: 1145 CPSLCNVLKSGVLSRRVSPG---YVPACRAEDGGFSPVQCDQAQGSCWCVM-DSGEEVPG 1200

Query: 283  TSTRYVMPSCES 294
            T      P+CES
Sbjct: 1201 TRVTGGQPACES 1212



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 62/234 (26%), Positives = 89/234 (38%), Gaps = 39/234 (16%)

Query: 119  GEDGSFTQVQCHTYTGYCWCVTPDGKPISGS-SVQNKTPVCSGSVTDKPLSQGNSGRKDD 177
            G    F+    H     CWCV   G+ + G  S  +K P C GS  +  L      R+ +
Sbjct: 881  GSYSDFSTPLAHFDLRNCWCVDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETE 940

Query: 178  ------GSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQER 231
                   S   P  E+  V  G  +    L +  L           +R S+  Y+     
Sbjct: 941  EIVSASNSSRFPLGESFLVAKGIRLRNEDLGLPPLFPPREAFAEQFLRGSD--YAIRLAA 998

Query: 232  QSALEEAQQNP-------------REGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGR 278
            QS L   Q+               R G  +P+C   G ++PVQCH  TG+CWCV  + G 
Sbjct: 999  QSTLSFYQRRRFSPDDSAGASALLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCV-DEKGG 1057

Query: 279  PLPG--TSTRYVMPSC-------------ESDARAKTTEADDPFKDRELPGCPE 317
             +PG  T+    +P C              S  +A++ E   P KD  +P C E
Sbjct: 1058 FIPGSLTARSLQIPQCPTTCEKSRTSGLLSSWKQARSQENPSP-KDLFVPACLE 1110



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 54   PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQ--SKCRLERAQALEQAKKPQE 111
            P C   G             C DP  G   R     + Q  S C + ++  L +   P  
Sbjct: 1106 PACLETGEYARLQASGAGTWCVDPASGEELRPGSSSSAQCPSLCNVLKSGVLSRRVSPG- 1164

Query: 112  AVFVPEC-GEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVC 158
              +VP C  EDG F+ VQC    G CWCV   G+ + G+ V    P C
Sbjct: 1165 --YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPAC 1210



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156
           +E   + +  ++  E +FVP C  +GS+  VQC  ++G CWCV   GK + GS V+   P
Sbjct: 599 METVLSSQTCEQTPERLFVPSCTTEGSYEDVQC--FSGECWCVNSWGKELPGSRVRGGQP 656

Query: 157 VC 158
            C
Sbjct: 657 RC 658



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 95  CRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK 154
           C L+R  A  +     +A +VP+C EDGSF  VQC      CWCV  +G  + GS    +
Sbjct: 34  CELQRETAFLK-----QADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGR 88

Query: 155 TPVC 158
              C
Sbjct: 89  PVAC 92



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 93  SKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ 152
           +KC +ER  A           +VP C  +G +  VQC T  G CWCV   GK + G+  Q
Sbjct: 299 TKCEVERFTATSFGHP-----YVPSCRRNGDYQAVQCQT-EGPCWCVDAQGKEMHGTRQQ 352

Query: 153 NKTPVCS 159
            + P C+
Sbjct: 353 GEPPSCA 359



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 8/115 (6%)

Query: 54  PICASDGRSYESMCEYQRAKC------RDPTLGVVHRGRCKDAGQSKCRLERAQALEQAK 107
           P CA DG      C+     C          LG    GR   A  S C+L++ Q L    
Sbjct: 50  PQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGR-PVACLSFCQLQKQQILLSGY 108

Query: 108 -KPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGS 161
               +  ++P+C + G +  VQC      CWCV  +G  + G+    +   C  S
Sbjct: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS 163



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)

Query: 236 EEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD 295
           +  +Q P E + +P C   G Y+ VQC   +G CWCV    G+ LPG+  R   P C +D
Sbjct: 606 QTCEQTP-ERLFVPSCTTEGSYEDVQCF--SGECWCV-NSWGKELPGSRVRGGQPRCPTD 661



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 12/112 (10%)

Query: 47  CSRTQPK---PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLE----- 98
           C +T  +   P C ++G   +  C      C + + G    G     GQ +C  +     
Sbjct: 608 CEQTPERLFVPSCTTEGSYEDVQCFSGECWCVN-SWGKELPGSRVRGGQPRCPTDCEKQR 666

Query: 99  -RAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGS 149
            R Q+L  ++     +FVP C  +G F  VQC  +   C+CV  +G+ I G+
Sbjct: 667 ARMQSLMGSQPAGSTLFVPACTSEGHFLPVQC--FNSECYCVDAEGQAIPGT 716



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 227 CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTR 286
           C  ++Q  L     N  +   +P+C   G Y PVQC      CWCV  + G  + GT   
Sbjct: 96  CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAE-GMEVYGTRQL 154

Query: 287 YVMPSCESDARAKTTEADDPFKDRELPGC-PEGKKMEFITSLLDALTTDMV 336
                C      +         D+  P C  EG+ M      ++  TTDM+
Sbjct: 155 GRPKRCPRSCEIRNRRLLHGVGDKSPPQCSAEGEFMPVQCKFVN--TTDMM 203



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 67/276 (24%), Positives = 102/276 (36%), Gaps = 54/276 (19%)

Query: 45  LHCSRTQPKPICASDGRSYESMCEYQRAKC------RDPTLGVVHRGRCKDAGQSKCRLE 98
           ++ + T   P C   G      C+ Q+ +C           G    GR K   +S C + 
Sbjct: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS-CEIR 167

Query: 99  RAQALEQA--KKPQEAVFVPECGEDGSFTQVQC--------------HTYTGYCWCVTPD 142
             + L     K P      P+C  +G F  VQC              H+Y  +     PD
Sbjct: 168 NRRLLHGVGDKSP------PQCSAEGEFMPVQCKFVNTTDMMIFDLVHSYNRF-----PD 216

Query: 143 GKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEI----TA 198
              ++ SS Q + P  SG       SQG     + G +         +F G ++    T 
Sbjct: 217 AF-VTFSSFQRRFPEVSGYCHCAD-SQGRE-LAETGLELLLDEIYDTIFAGLDLPSTFTE 273

Query: 199 PTLW--IKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGL 256
            TL+  ++   +    + +   R   K   C+ ER +A             +P C   G 
Sbjct: 274 TTLYRILQRRFLAVQSVISGRFRCPTK---CEVERFTATSFGHP------YVPSCRRNGD 324

Query: 257 YKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSC 292
           Y+ VQC Q+ G CWCV    G+ + GT  +   PSC
Sbjct: 325 YQAVQC-QTEGPCWCVDAQ-GKEMHGTRQQGEPPSC 358



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 212 KLNNTNIRNSEKVYSCDQERQSALEEA---QQNPREGIVIPECAPGGLYKPVQCHQSTGY 268
           +L  + +R  +     D E+Q A  ++    Q     + +P C   G + PVQC  S   
Sbjct: 645 ELPGSRVRGGQPRCPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE-- 702

Query: 269 CWCVLVDTGRPLPGTSTRYVMP-SCESDARAKTTEA 303
           C+CV  + G+ +PGT +    P  C +  + ++ +A
Sbjct: 703 CYCVDAE-GQAIPGTRSAIGKPKKCPTPCQLQSEQA 737



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 14/53 (26%), Positives = 28/53 (52%), Gaps = 6/53 (11%)

Query: 220 NSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCV 272
           +++ +  C+ +R++A        ++   +P+CA  G ++ VQC      CWCV
Sbjct: 27  DAQPLRPCELQRETAFL------KQADYVPQCAEDGSFQTVQCQNDGRSCWCV 73



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 16/92 (17%)

Query: 54  PICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSK-----CRLERAQAL---EQ 105
           P C S+G      C      C D   G    G     G+ K     C+L+  QA     Q
Sbjct: 685 PACTSEGHFLPVQCFNSECYCVDAE-GQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQ 743

Query: 106 AKKPQEAV-------FVPECGEDGSFTQVQCH 130
           A     ++       ++P+C  DG + QVQC+
Sbjct: 744 ALLSNSSMLPTLSDTYIPQCSTDGQWRQVQCN 775



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 6/56 (10%)

Query: 101  QALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTP----DGKPISGSSVQ 152
            QA  Q     + +FVP C E G + ++Q        WCV P    + +P S SS Q
Sbjct: 1091 QARSQENPSPKDLFVPACLETGEYARLQAS--GAGTWCVDPASGEELRPGSSSSAQ 1144


>gi|115298674 nidogen 1 precursor [Homo sapiens]
          Length = 1247

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 42/126 (33%), Positives = 59/126 (46%), Gaps = 7/126 (5%)

Query: 48  SRTQPKPICASDGRSYESMCE--YQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQ 105
           SR  P   C +   S+   C+  YQ    R    G V + RC+   + +  L  A A + 
Sbjct: 809 SRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVP-GEVEKTRCQH--EREHILGAAGATDP 865

Query: 106 AKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ-NKTPVCSGSVTD 164
            +     +FVPEC   G +   QCH  TGYCWCV  DG+ + G+  +   TP C  +V  
Sbjct: 866 QRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVA- 924

Query: 165 KPLSQG 170
            P+ QG
Sbjct: 925 PPIHQG 930



 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 35/74 (47%), Positives = 40/74 (54%), Gaps = 7/74 (9%)

Query: 227 CDQERQSALEEA-----QQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLP 281
           C  ER+  L  A     Q+    G+ +PEC   G Y P QCH STGYCWCV  D GR + 
Sbjct: 849 CQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRD-GREVE 907

Query: 282 GTSTRYVM-PSCES 294
           GT TR  M P C S
Sbjct: 908 GTRTRPGMTPPCLS 921


>gi|12383051 transmembrane protein with EGF-like and two
           follistatin-like domains 2 [Homo sapiens]
          Length = 374

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 6/76 (7%)

Query: 43  CNLHCSRTQPKPICASDGRSYESMCEYQRAKC-RDPTLGVVHRGRCKDAGQSKCRLE--- 98
           CN+ CS+T   P+CASDG+SY++ C+ + A C +   + V+  GRC+D   +  + E   
Sbjct: 182 CNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGH 241

Query: 99  --RAQALEQAKKPQEA 112
             R    E A K +E+
Sbjct: 242 YARTDYAENANKLEES 257



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 10/111 (9%)

Query: 43  CNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPT-LGVVHRGRC-KDAGQSKCRLERA 100
           C   C+     P+C S+G SY++ C  ++A C+  + + VV  G C  DAG         
Sbjct: 91  CQFKCNNDYV-PVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHE 149

Query: 101 QALEQAKKPQEAV----FVPECGEDGSFTQVQCH---TYTGYCWCVTPDGK 144
            + E ++K         F  EC ED       C+   + T +      DGK
Sbjct: 150 GSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGK 200


>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan (testican) 2 isoform 2 [Homo sapiens]
          Length = 424

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 70/281 (24%), Positives = 111/281 (39%), Gaps = 36/281 (12%)

Query: 27  HRTTGPRF-LISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRG 85
           HR   P   L  ++D  C   C   Q   +C SDG +Y S+C+ ++  C       V   
Sbjct: 119 HRIKQPTVKLHGNKDSICK-PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAV--- 174

Query: 86  RCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKP 145
           RC+  G   C  E+A       KP+        G+D +    +   +    + +  +   
Sbjct: 175 RCE--GPCPCPTEQAATSTADGKPETCT-----GQDLADLGDRLRDW----FQLLHENSK 223

Query: 146 ISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVF-DGDEITAPTLWIK 204
            +GS+     P    S  DK L  G S +   G   +    +  +F D  E+ A  L   
Sbjct: 224 QNGSASSVAGP---ASGLDKSL--GASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKY 278

Query: 205 HLVIKD-----SKLNNTNIRNSEKVYSCDQERQSALEEAQQ-------NPREGIVIPECA 252
            + I+          +  +  +E  +   +E+   L E ++         + GI IP C 
Sbjct: 279 EVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCD 338

Query: 253 PGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCE 293
             G Y+ +QC QS+G CWCV    G  L GT T +  P C+
Sbjct: 339 EDGYYRKMQCDQSSGDCWCV-DQLGLELTGTRT-HGSPDCD 377



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156
           LER Q  E AKK +  +F+P C EDG + ++QC   +G CWCV   G  ++G+     +P
Sbjct: 317 LERIQIQEAAKK-KPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHG-SP 374

Query: 157 VCSGSVTDKPLSQGNSGRKDDGSKPT 182
            C   V          G +D+  K T
Sbjct: 375 DCDDIVGFSGDFGSGVGWEDEEEKET 400



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 17/148 (11%)

Query: 284 STRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAA 343
           S++ +   CE      T +A     D    G PE    + +  L D L  D  Q ++  +
Sbjct: 168 SSKQLAVRCEGPCPCPTEQAATSTAD----GKPETCTGQDLADLGDRLR-DWFQLLHENS 222

Query: 344 PTGGGRFSEPDPSHTLEERV-------VHWYFSQLDSNSSNDINKREMKPFKRYVKKKAK 396
              G   S   P+  L++ +       + W FS+LD+++   +++ E+           K
Sbjct: 223 KQNGSASSVAGPASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINL-----DK 277

Query: 397 PKKCARRFTDYCDLNKDKVISLPELKGC 424
            + C R F + CD  KD  +S  E   C
Sbjct: 278 YEVCIRPFFNSCDTYKDGRVSTAEWCFC 305


>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan 1 precursor [Homo sapiens]
          Length = 439

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 97  LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156
           + R Q L + K    A F+P C E+G +   QCH  TG CWCV   G  ++GS  Q    
Sbjct: 317 MNRIQKLSKGKSLLGA-FIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVS 375

Query: 157 VCSGSVTDKPLSQGNS 172
                 T      G S
Sbjct: 376 CEEEQETSGDFGSGGS 391



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 77/307 (25%), Positives = 106/307 (34%), Gaps = 67/307 (21%)

Query: 47  CSRTQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCK---DAGQSKCRLERAQA 102
           C   Q   +C SDG SY S C+ +   C    +L  +  G C    +    K + ER+  
Sbjct: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSAC 198

Query: 103 LEQAKKPQEAVFVPECG---EDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNK----- 154
            ++  +   +      G   ED +                    KP S ++ Q +     
Sbjct: 199 TDKELRNLASRLKDWFGALHEDANRVI-----------------KPTSSNTAQGRFDTSI 241

Query: 155 TPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTL-----WIKHLVIK 209
            P+C  S+       G    K D       M    + D  EI A  L      IK L   
Sbjct: 242 LPICKDSL-------GWMFNKLD-------MNYDLLLDPSEINAIYLDKYEPCIKPLFNS 287

Query: 210 DSKLNNTNIRNSEKVYS--------CDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQ 261
                +  + N+E  Y         C  E     + ++     G  IP C   G YK  Q
Sbjct: 288 CDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQ 347

Query: 262 CHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESD--------ARAKTTEADDPFKDREL- 312
           CH STG CWCV    G  L G S +    SCE +        +       DD   +REL 
Sbjct: 348 CHGSTGQCWCV-DKYGNELAG-SRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELG 405

Query: 313 PGCPEGK 319
           P   EGK
Sbjct: 406 PKDKEGK 412


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 11/81 (13%)

Query: 53  KPICASDGRSYESMCEYQRAKCRDP-TLGVVHRGRCKDAGQ----------SKCRLERAQ 101
           +P+CA DGR+Y+S C  Q+A+CR    +   H+G C  A            + C ++  Q
Sbjct: 426 RPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQ 485

Query: 102 ALEQAKKPQEAVFVPECGEDG 122
           A  +  +   +++ P CG DG
Sbjct: 486 AACECLQACSSLYDPVCGSDG 506



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 35/105 (33%), Positives = 44/105 (41%), Gaps = 25/105 (23%)

Query: 42  QCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLG----VVHRGRCKDAGQSK--- 94
           +C   CS     P+C SDG +Y S CE +   C   TLG    V  +G C   GQ +   
Sbjct: 489 ECLQACSSLYD-PVCGSDGVTYGSACELEATAC---TLGREIQVARKGPCDRCGQCRFGA 544

Query: 95  -CRLERAQALEQAKKPQEAVFV--PECGEDGSFTQVQCHTYTGYC 136
            C  E  + +     P E V +  P CG DG       HTY   C
Sbjct: 545 LCEAETGRCV----CPSECVALAQPVCGSDG-------HTYPSEC 578



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 20/113 (17%)

Query: 43  CNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPT-LGVVHRGRCKDAGQSKCRLERAQ 101
           C+  C      P+C SDG +Y + CE ++A+C     L V  +G C+  G +   L    
Sbjct: 705 CDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACR--GPTFAPLPPVA 762

Query: 102 ALEQAKKP----QEAVFVP------------ECGEDGSFTQVQCHTYTGYCWC 138
            L  A+ P    Q+ +               +C   GS+    C   TG C C
Sbjct: 763 PLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGT-CDPATGQCSC 814



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 31/114 (27%), Positives = 43/114 (37%), Gaps = 20/114 (17%)

Query: 47  CSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQA 106
           C    P P+C SDG +Y S CE + A C   T   +   R     Q++C    + +    
Sbjct: 623 CEHPPPGPVCGSDGVTYGSACELREAACLQQT--QIEEARAGPCEQAECGSGGSGS---- 676

Query: 107 KKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQN--KTPVC 158
                       GEDG   Q  C    G     + DG  +   S Q+   +PVC
Sbjct: 677 ------------GEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVC 718



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 19/95 (20%)

Query: 54  PICASDGRSYESMCEYQRA-KCRDPTLGVVHRGRC--KDAGQSKCRLERAQALEQAKKPQ 110
           P+C  DG +YE+ C   R+   R   L  V  G+C  +D     CR   A  L +  +P+
Sbjct: 355 PVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRF-NAVCLSRRGRPR 413

Query: 111 --------EAVFVPECGEDGSFTQVQCHTYTGYCW 137
                   +  + P C +DG        TY   CW
Sbjct: 414 CSCDRVTCDGAYRPVCAQDG-------RTYDSDCW 441



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 54  PICASDGRSYESMCEYQRAKC-RDPTLGVVHRGRC 87
           P+C SD  +Y + CE QRA+C +   + ++ RG C
Sbjct: 208 PVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPC 242



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 27/98 (27%), Positives = 37/98 (37%), Gaps = 12/98 (12%)

Query: 43  CNLHCSRTQPKPICASDGRSYESMCEYQRAKC-RDPTLGVVHRGRC-------KDAGQSK 94
           C   C       +C SDG  Y   C+  R  C R   +     G C        D  +S 
Sbjct: 272 CPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRS- 330

Query: 95  CRLE-RAQALEQAKKPQE--AVFVPECGEDGSFTQVQC 129
           CR+  R +  E   +P+   A   P CG+DG   +  C
Sbjct: 331 CRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDC 368



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 45  LHCSRTQPKPICASDGRSYESMCEYQRAKCRDP-TLGVVHRGRCKDA 90
           L C       +C SDG +Y + C+ +   CR    + +   G C++A
Sbjct: 926 LTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 59/256 (23%), Positives = 89/256 (34%), Gaps = 65/256 (25%)

Query: 47  CSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQA 106
           C    P P+C SDG +Y   C+ +   C    LG     +C+  G   C  ++  +  + 
Sbjct: 139 CPVVYPSPVCGSDGHTYSFQCKLEYQAC---VLGKQISVKCE--GHCPCPSDKPTSTSRN 193

Query: 107 KKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKP 166
            K            D  F +V       +        K +  S  QNK          K 
Sbjct: 194 VK--------RACSDLEFREVANRLRDWF--------KALHESGSQNKKT--------KT 229

Query: 167 LSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVY- 225
           L +    R D    P        +F+  +          L++  S+L +  +  +E+   
Sbjct: 230 LLRPERSRFDTSILPICKDSLGWMFNRLDTNYD------LLLDQSELRSIYLDKNEQCTK 283

Query: 226 ----SCDQERQSALE--------EAQQNP-----------REGI------VIPECAPGGL 256
               SCD  + S +         + QQ+P           R+G+       IP C   G 
Sbjct: 284 AFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGY 343

Query: 257 YKPVQCHQSTGYCWCV 272
           YKP QCH S G CWCV
Sbjct: 344 YKPTQCHGSVGQCWCV 359



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 114 FVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSV 151
           ++P C EDG +   QCH   G CWCV   G  + GS +
Sbjct: 334 YIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 371



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 366 WYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGC 424
           W F++LD+N    +++ E++    Y+ K    ++C + F + CD  KD +IS  E   C
Sbjct: 252 WMFNRLDTNYDLLLDQSELRSI--YLDKN---EQCTKAFFNSCDTYKDSLISNNEWCYC 305


>gi|93141001 testican 3 isoform 2 [Homo sapiens]
          Length = 436

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 59/256 (23%), Positives = 89/256 (34%), Gaps = 65/256 (25%)

Query: 47  CSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQA 106
           C    P P+C SDG +Y   C+ +   C    LG     +C+  G   C  ++  +  + 
Sbjct: 142 CPVVYPSPVCGSDGHTYSFQCKLEYQAC---VLGKQISVKCE--GHCPCPSDKPTSTSRN 196

Query: 107 KKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKP 166
            K            D  F +V       +        K +  S  QNK          K 
Sbjct: 197 VK--------RACSDLEFREVANRLRDWF--------KALHESGSQNKKT--------KT 232

Query: 167 LSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVY- 225
           L +    R D    P        +F+  +          L++  S+L +  +  +E+   
Sbjct: 233 LLRPERSRFDTSILPICKDSLGWMFNRLDTNYD------LLLDQSELRSIYLDKNEQCTK 286

Query: 226 ----SCDQERQSALE--------EAQQNP-----------REGI------VIPECAPGGL 256
               SCD  + S +         + QQ+P           R+G+       IP C   G 
Sbjct: 287 AFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGY 346

Query: 257 YKPVQCHQSTGYCWCV 272
           YKP QCH S G CWCV
Sbjct: 347 YKPTQCHGSVGQCWCV 362



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 114 FVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSV 151
           ++P C EDG +   QCH   G CWCV   G  + GS +
Sbjct: 337 YIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 374



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 366 WYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGC 424
           W F++LD+N    +++ E++    Y+ K    ++C + F + CD  KD +IS  E   C
Sbjct: 255 WMFNRLDTNYDLLLDQSELRSI--YLDKN---EQCTKAFFNSCDTYKDSLISNNEWCYC 308


>gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]
          Length = 303

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 4/68 (5%)

Query: 364 VHWYFSQLDSNSSND-INKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELK 422
           VHW F QLD +  +  ++  E+ P +  +      + C  RF + CDL+ DK I+L E  
Sbjct: 231 VHWQFGQLDQHPIDGYLSHTELAPLRAPL---IPMEHCTTRFFETCDLDNDKYIALDEWA 287

Query: 423 GCLGVSKE 430
           GC G+ ++
Sbjct: 288 GCFGIKQK 295


>gi|68448544 CD74 antigen isoform a [Homo sapiens]
          Length = 296

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 114 FVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSG 173
           F P+C E+G++  +QC+   GYCWCV P+G  +  +  +     CS S+  +  S G   
Sbjct: 228 FRPKCDENGNYLPLQCYGSIGYCWCVFPNGTEVPNTRSRGHHN-CSESLELEDPSSGLGV 286

Query: 174 RKDD 177
            K D
Sbjct: 287 TKQD 290



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 249 PECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTR 286
           P+C   G Y P+QC+ S GYCWCV    G  +P T +R
Sbjct: 230 PKCDENGNYLPLQCYGSIGYCWCVF-PNGTEVPNTRSR 266


>gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]
          Length = 263

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 34/166 (20%)

Query: 19  VQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCR-DP 77
           V+  P +  R  G R    +  P C+   +R Q   +C SDG +Y   CE + A+CR  P
Sbjct: 102 VECGPGKACRMLGGRPRC-ECAPDCSGLPARLQ---VCGSDGATYRDECELRAARCRGHP 157

Query: 78  TLGVVHRGRCK-----------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120
            L V++RGRC+                   G + C + RA        P + +    CG 
Sbjct: 158 DLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQEL----CGN 213

Query: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKP 166
           +       CH     C+     G   +GS        C+G+  + P
Sbjct: 214 NNVTYISSCHMRQATCFLGRSIGVRHAGS--------CAGTPEEPP 251


>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
          Length = 317

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)

Query: 43  CNLHCSR-TQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCKDA-------GQS 93
           C   CS  T   P+C  DG++Y + C   +A+C++ P L V ++GRCK         G S
Sbjct: 118 CAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSS 177

Query: 94  KCRLERAQ----------ALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDG 143
            C +++              E A   Q       CG DG      CH     C      G
Sbjct: 178 TCVVDQTNNAYCVTCNRICPEPASSEQYL-----CGNDGVTYSSACHLRKATCLLGRSIG 232

Query: 144 KPISGSSVQNKT 155
               G  ++ K+
Sbjct: 233 LAYEGKCIKAKS 244



 Score = 32.3 bits (72), Expect = 0.86
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 53  KPICASDGRSYESMCEYQRAKCRDPT-LGVVHRGRC 87
           +P+CASD  +Y S C  + A C     L V H G C
Sbjct: 281 EPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316


>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
          Length = 344

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 24/132 (18%)

Query: 43  CNLHCSR-TQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRCKDA-------GQS 93
           C   CS  T   P+C  DG++Y + C   +A+C++ P L V ++GRCK         G S
Sbjct: 118 CAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSS 177

Query: 94  KCRLERAQ----------ALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDG 143
            C +++              E A   Q       CG DG      CH     C      G
Sbjct: 178 TCVVDQTNNAYCVTCNRICPEPASSEQYL-----CGNDGVTYSSACHLRKATCLLGRSIG 232

Query: 144 KPISGSSVQNKT 155
               G  ++ K+
Sbjct: 233 LAYEGKCIKAKS 244



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 53  KPICASDGRSYESMCEYQRAKCRDPT-LGVVHRGRCKDAGQ 92
           +P+CASD  +Y S C  + A C     L V H G C    +
Sbjct: 281 EPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISE 321


>gi|190194423 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 364 VHWYFSQLDSNSSNDI-NKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELK 422
           VHW FS+LD +  + +    E+ P +  +      + C  RF + CD NKDK I+L E  
Sbjct: 592 VHWQFSELDQHPMDRVLTHSELAPLRASL---VPMEHCITRFFEECDPNKDKHITLKEWG 648

Query: 423 GCLGVSKE 430
            C G+ +E
Sbjct: 649 HCFGIKEE 656


>gi|190341024 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 364 VHWYFSQLDSNSSNDI-NKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELK 422
           VHW FS+LD +  + +    E+ P +  +      + C  RF + CD NKDK I+L E  
Sbjct: 592 VHWQFSELDQHPMDRVLTHSELAPLRASL---VPMEHCITRFFEECDPNKDKHITLKEWG 648

Query: 423 GCLGVSKE 430
            C G+ +E
Sbjct: 649 HCFGIKEE 656


>gi|29568105 transmembrane protein with EGF-like and two
           follistatin-like domains 1 [Homo sapiens]
          Length = 380

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 7/80 (8%)

Query: 43  CNLHCSRTQPKPICASDGRSYESMCEYQRAKC-RDPTLGVVHRGRCKDA------GQSKC 95
           CN+ CS     P+CASDG SY + C  + A C +   + + H G C D       G+   
Sbjct: 190 CNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDD 249

Query: 96  RLERAQALEQAKKPQEAVFV 115
            L+    ++ A   +E V++
Sbjct: 250 GLQYRPDVKDASDQREDVYI 269



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 38/179 (21%), Positives = 70/179 (39%), Gaps = 23/179 (12%)

Query: 43  CNLHCSRTQPKPICASDGRSYESMCEYQRAKCR-DPTLGVVHRGRC-----KDAGQSKCR 96
           C   C  T   P+C S+G +Y++ C  +RA C+    + V+ RG C       +G+ +  
Sbjct: 99  CQFQC-HTNYIPVCGSNGDTYQNECFLRRAACKHQKEITVIARGPCYSDNGSGSGEGEEE 157

Query: 97  LERAQALEQAKKPQEAVFVPECGED----GSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ 152
              A+   +  K     +  EC ED    G    + C  Y+    C +      +   V+
Sbjct: 158 GSGAEVHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVR 217

Query: 153 NKTPVCSGSVTDKPLSQGNS-------GRKDDGSKPTPTM-----ETQPVFDGDEITAP 199
             + +    +  + L            G+KDDG +  P +     + + V+ G+ +  P
Sbjct: 218 EASCIKQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCP 276


>gi|4504615 insulin-like growth factor binding protein 1 precursor
           [Homo sapiens]
          Length = 259

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 12/76 (15%)

Query: 95  CRLERAQALEQAKKPQEA-------VFVPECGEDGSFTQVQCHT----YTGYCWCVTP-D 142
           CR+E  + +E   K QE         ++P C ++G +   QC T      G CWCV P +
Sbjct: 176 CRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWN 235

Query: 143 GKPISGSSVQNKTPVC 158
           GK I GS      P C
Sbjct: 236 GKRIPGSPEIRGDPNC 251



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 15/121 (12%)

Query: 188 QPVFDGDEITAPT------LWIKHLVIKDSK-LNNTNIRNSEKVYSCDQERQ-SALEEAQ 239
           + + D   + AP+      LW        SK L+ TNI+  ++    +  R   +L +AQ
Sbjct: 132 EELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKAQ 191

Query: 240 QNPREGI---VIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGRPLPGTSTRYVMPSC 292
           +   E I    +P C   G Y   QC  S     G CWCV    G+ +PG+      P+C
Sbjct: 192 ETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNC 251

Query: 293 E 293
           +
Sbjct: 252 Q 252


>gi|62243068 insulin-like growth factor binding protein 3 isoform b
           precursor [Homo sapiens]
          Length = 291

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 10/68 (14%)

Query: 227 CDQERQSALEEAQ----QNPREGIVIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGR 278
           C +E +  L   +     +PR G+ IP C   G YK  QC  S     G+CWCV    G+
Sbjct: 213 CRREMEDTLNHLKFLNVLSPR-GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCV-DKYGQ 270

Query: 279 PLPGTSTR 286
           PLPG +T+
Sbjct: 271 PLPGYTTK 278



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%)

Query: 95  CRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTG----YCWCVTPDGKPI 146
           CR E    L   K         V +P C + G + + QC    G    +CWCV   G+P+
Sbjct: 213 CRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPL 272

Query: 147 SGSSVQNKTPVCSGSVTDK 165
            G + + K  V   S+  K
Sbjct: 273 PGYTTKGKEDVHCYSMQSK 291


>gi|62243248 insulin-like growth factor binding protein 3 isoform a
           precursor [Homo sapiens]
          Length = 297

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 10/68 (14%)

Query: 227 CDQERQSALEEAQ----QNPREGIVIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGR 278
           C +E +  L   +     +PR G+ IP C   G YK  QC  S     G+CWCV    G+
Sbjct: 219 CRREMEDTLNHLKFLNVLSPR-GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCV-DKYGQ 276

Query: 279 PLPGTSTR 286
           PLPG +T+
Sbjct: 277 PLPGYTTK 284



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%)

Query: 95  CRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTG----YCWCVTPDGKPI 146
           CR E    L   K         V +P C + G + + QC    G    +CWCV   G+P+
Sbjct: 219 CRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPL 278

Query: 147 SGSSVQNKTPVCSGSVTDK 165
            G + + K  V   S+  K
Sbjct: 279 PGYTTKGKEDVHCYSMQSK 297


>gi|62243290 insulin-like growth factor binding protein 4 precursor
           [Homo sapiens]
          Length = 258

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 10/67 (14%)

Query: 226 SCDQERQSALEE---AQQNPREG---IVIPECAPGGLYKPVQCHQST----GYCWCVLVD 275
           SC  E   ALE    +Q    E    I IP C   G + P QCH +     G CWCV   
Sbjct: 173 SCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRK 232

Query: 276 TGRPLPG 282
           TG  LPG
Sbjct: 233 TGVKLPG 239



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 11/59 (18%)

Query: 92  QSKCRLERAQALEQAKKPQEAVF-------VPECGEDGSFTQVQCHT----YTGYCWCV 139
           Q  C+ E  +ALE+    Q           +P C  +G+F   QCH       G CWCV
Sbjct: 171 QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV 229


>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
           [Homo sapiens]
          Length = 328

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 14/80 (17%)

Query: 227 CDQERQSALEEA-------QQNPREGIV---IPECAPGGLYKPVQCHQST----GYCWCV 272
           C QE    LE         ++ P E +    IP C   GLY   QC  S     G CWCV
Sbjct: 230 CQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCV 289

Query: 273 LVDTGRPLPGTSTRYVMPSC 292
             +TG+ + G  T    P C
Sbjct: 290 NPNTGKLIQGAPTIRGDPEC 309



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 16/83 (19%)

Query: 92  QSKCRLERAQALEQA---KKPQE--------AVFVPECGEDGSFTQVQC----HTYTGYC 136
           ++ C+ E  Q LE+    + P E        ++ +P C + G +   QC    +   G C
Sbjct: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286

Query: 137 WCVTPD-GKPISGSSVQNKTPVC 158
           WCV P+ GK I G+      P C
Sbjct: 287 WCVNPNTGKLIQGAPTIRGDPEC 309


>gi|10834982 insulin-like growth factor binding protein 5 [Homo
           sapiens]
          Length = 272

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 218 IRNSEKVYSCDQERQSALEEAQQNPR---EGIVIPECAPGGLYKPVQCHQS----TGYCW 270
           +R   +   C +  +++L+E + +PR     + +P C   G YK  QC  S     G CW
Sbjct: 183 MRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICW 242

Query: 271 CVLVDTGRPLPG 282
           CV    G  LPG
Sbjct: 243 CV-DKYGMKLPG 253



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 8/69 (11%)

Query: 88  KDAGQSKCRLERAQALEQAKKPQE----AVFVPECGEDGSFTQVQCH----TYTGYCWCV 139
           +++ Q  CR     +L++ K        AV++P C   G + + QC        G CWCV
Sbjct: 185 QESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV 244

Query: 140 TPDGKPISG 148
              G  + G
Sbjct: 245 DKYGMKLPG 253


>gi|11321593 insulin-like growth factor binding protein 6 [Homo
           sapiens]
          Length = 240

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 88  KDAGQSKCRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTGY----CWCV 139
           +D     CR      L+Q +    +  + ++VP C   G + + QC +  G     CWCV
Sbjct: 156 QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCV 215

Query: 140 TPDGKPISGSSVQNKTPVC 158
              GK + GS   N +  C
Sbjct: 216 DRMGKSLPGSPDGNGSSSC 234



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 9/89 (10%)

Query: 211 SKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREG---IVIPECAPGGLYKPVQCHQSTG 267
           S+ N+  ++++E +  C +   S L++ Q     G   + +P C   G Y+  QC  S G
Sbjct: 148 SQPNSAGVQDTE-MGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQG 206

Query: 268 Y----CWCVLVDTGRPLPGTSTRYVMPSC 292
                CWCV    G+ LPG+       SC
Sbjct: 207 QRRGPCWCV-DRMGKSLPGSPDGNGSSSC 234


>gi|189242612 complement component 6 precursor [Homo sapiens]
          Length = 934

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 28/121 (23%), Positives = 48/121 (39%), Gaps = 16/121 (13%)

Query: 26  GHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESM----CEYQRAKC-RDPTLG 80
           G + +G   +    +  C+ H      + +C  D  S +      C++   KC  +  L 
Sbjct: 776 GQKQSGSECICMSPEEDCSHHS-----EDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLH 830

Query: 81  VVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVT 140
            +H G C+D  Q +  LER +    + K +       CG D  +   +C   T  C C+ 
Sbjct: 831 FLHIGSCQDGRQLEWGLERTRLSSNSTKKES------CGYDTCYDWEKCSASTSKCVCLL 884

Query: 141 P 141
           P
Sbjct: 885 P 885


>gi|169636415 complement component 6 precursor [Homo sapiens]
          Length = 934

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 28/121 (23%), Positives = 48/121 (39%), Gaps = 16/121 (13%)

Query: 26  GHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESM----CEYQRAKC-RDPTLG 80
           G + +G   +    +  C+ H      + +C  D  S +      C++   KC  +  L 
Sbjct: 776 GQKQSGSECICMSPEEDCSHHS-----EDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLH 830

Query: 81  VVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVT 140
            +H G C+D  Q +  LER +    + K +       CG D  +   +C   T  C C+ 
Sbjct: 831 FLHIGSCQDGRQLEWGLERTRLSSNSTKKES------CGYDTCYDWEKCSASTSKCVCLL 884

Query: 141 P 141
           P
Sbjct: 885 P 885


>gi|54792136 follistatin-like 4 [Homo sapiens]
          Length = 842

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%)

Query: 31  GPRFLISDR--DPQCN-LHCSRTQPKPICASDGRSYESMCEYQRAKC-RDPTLGVVHRGR 86
           G R ++S +  +P+C  L   R    P+C SDGR YE+ C+  RA C     + V+H   
Sbjct: 73  GSRCVLSRKTGEPECQCLEACRPSYVPVCGSDGRFYENHCKLHRAACLLGKRITVIHSKD 132

Query: 87  C 87
           C
Sbjct: 133 C 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,793,480
Number of Sequences: 37866
Number of extensions: 1052357
Number of successful extensions: 3032
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2860
Number of HSP's gapped (non-prelim): 174
length of query: 434
length of database: 18,247,518
effective HSP length: 105
effective length of query: 329
effective length of database: 14,271,588
effective search space: 4695352452
effective search space used: 4695352452
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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