Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 224548923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
(562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 1176 0.0
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 1164 0.0
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 140 2e-33
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 140 4e-33
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 140 4e-33
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 138 2e-32
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 138 2e-32
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 133 4e-31
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 133 4e-31
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 128 1e-29
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 128 1e-29
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 122 1e-27
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 104 2e-22
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 97 4e-20
gi|223890259 midline 2 isoform 2 [Homo sapiens] 84 3e-16
gi|223890257 midline 2 isoform 1 [Homo sapiens] 84 3e-16
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 80 5e-15
gi|148833499 midline 1 [Homo sapiens] 79 1e-14
gi|4557753 midline 1 [Homo sapiens] 79 1e-14
gi|15451852 midline 1 [Homo sapiens] 79 1e-14
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 78 2e-14
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 78 2e-14
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi... 75 2e-13
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens] 75 2e-13
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens] 75 2e-13
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens] 75 2e-13
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens] 75 2e-13
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens] 75 2e-13
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi... 75 2e-13
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens] 75 2e-13
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 1176 bits (3041), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS 60
MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
Sbjct: 1 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS 60
Query: 61 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND 120
VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
Sbjct: 61 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND 120
Query: 121 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK 180
VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK
Sbjct: 121 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK 180
Query: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE 240
GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE
Sbjct: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE 240
Query: 241 LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE 300
LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE
Sbjct: 241 LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE 300
Query: 301 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV
Sbjct: 301 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
Query: 361 QYSTRPGVNDKIRFCPQEKAGQCRGYEIYDLHRAREKQTASFTLLCKDAAGEIMGRGGDN 420
QYSTRPGVNDKIRFCPQEKAGQCRGYEIYDLHRAREKQTASFTLLCKDAAGEIMGRGGDN
Sbjct: 361 QYSTRPGVNDKIRFCPQEKAGQCRGYEIYDLHRAREKQTASFTLLCKDAAGEIMGRGGDN 420
Query: 421 VQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVR 480
VQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVR
Sbjct: 421 VQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVR 480
Query: 481 RKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNE 540
RKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNE
Sbjct: 481 RKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNE 540
Query: 541 KSECTWTGGQSAPRSLLRTVAL 562
KSECTWTGGQSAPRSLLRTVAL
Sbjct: 541 KSECTWTGGQSAPRSLLRTVAL 562
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 1164 bits (3012), Expect = 0.0
Identities = 562/580 (96%), Positives = 562/580 (96%), Gaps = 18/580 (3%)
Query: 1 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS 60
MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
Sbjct: 1 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS 60
Query: 61 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND 120
VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
Sbjct: 61 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND 120
Query: 121 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK 180
VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK
Sbjct: 121 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK 180
Query: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE 240
GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE
Sbjct: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE 240
Query: 241 LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE 300
LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE
Sbjct: 241 LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE 300
Query: 301 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV
Sbjct: 301 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
Query: 361 QYSTRPGVNDKIRFCPQEKAGQCRGYEIY------------------DLHRAREKQTASF 402
QYSTRPGVNDKIRFCPQEKAGQCRGYEIY DLHRAREKQTASF
Sbjct: 361 QYSTRPGVNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGEDLHRAREKQTASF 420
Query: 403 TLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVW 462
TLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVW
Sbjct: 421 TLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVW 480
Query: 463 VCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHG 522
VCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHG
Sbjct: 481 VCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHG 540
Query: 523 HKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL 562
HKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL
Sbjct: 541 HKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL 580
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 140 bits (354), Expect = 2e-33
Identities = 98/385 (25%), Positives = 177/385 (45%), Gaps = 41/385 (10%)
Query: 135 CDLCND-REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSR------IGK 187
C C++ RC C+ +LC C +AH+R + T H + G + +G
Sbjct: 199 CSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPGAAAAAQQLGLGP 258
Query: 188 PI----------------LCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVI 231
P C H E L L+C+ C P+C++C +G H H + +
Sbjct: 259 PFPGPPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTMGRHGGHSFIYLQEAL 318
Query: 232 HKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH 291
+LL Q +A++ ++ Q + ++ + + V ++V+ + + KA+EE
Sbjct: 319 QDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEER 378
Query: 292 RDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVV 351
+LL ++E IR K SL LQ +L Q L + + + + +L G L+IL+ + ++
Sbjct: 379 ECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRML 438
Query: 352 ERLRKLNKVQYSTRPGVNDKIRFCPQEKA--GQCRGYEIYD--------------LHRAR 395
++++L V+ +P +D++ F P ++A + + L RA
Sbjct: 439 AQVQELKTVRSLLQPQEDDRVMFTPPDQALYLAIKSFGFVSSGAFAPLTKATGDGLKRAL 498
Query: 396 EKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKE 455
+ + ASFT++ D GE GGD + V+ D + V D ++GTY +SY P+
Sbjct: 499 QGKVASFTVIGYDHDGEPRLSGGDLMSAVVLGPD--GNLFGAEVSDQQNGTYVVSYRPQL 556
Query: 456 PGVYTVWVCIKEQHVQGSPFTVMVR 480
G + V V + QH++ SPF V+V+
Sbjct: 557 EGEHLVSVTLCNQHIENSPFKVVVK 581
Score = 30.4 bits (67), Expect = 4.5
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 24/86 (27%)
Query: 41 LLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQ 100
+LPCLH C CLE + GG G+ + LK R CPVCD +
Sbjct: 58 VLPCLHAFCRPCLEAHR----LPAAGG-------GAAGEPLKLR---------CPVCDQK 97
Query: 101 VDLPMGGVKALTIDHLAVNDVMLESL 126
V L +A +D L + +L +L
Sbjct: 98 VVL----AEAAGMDALPSSAFLLSNL 119
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 140 bits (352), Expect = 4e-33
Identities = 102/346 (29%), Positives = 154/346 (44%), Gaps = 36/346 (10%)
Query: 39 PRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVC 97
P+LLPCLH+ C CL + E V I GG S G I Q+G++ CPVC
Sbjct: 140 PKLLPCLHSFCLRCLPEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVC 184
Query: 98 DA---QVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQTCKA 152
Q+DL +D+ V D S E VC C D C C
Sbjct: 185 RQECRQIDL---------VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGE 235
Query: 153 NLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCEFCDR 208
LC C +AH+R K T H + +D+ +G +P+ CPVH E+L+LFCE CDR
Sbjct: 236 WLCKTCIEAHQRVKFTKDHLIRKKEDVS--ESVGASGQRPVFCPVHKQEQLKLFCETCDR 293
Query: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
C+DC + EH+EH F ++ LL + A Q+ + +
Sbjct: 294 LTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNE 353
Query: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
+ V +++ I I + LL+QLE++ +++ L Q+ + L ++ +
Sbjct: 354 TNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVM 413
Query: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
FT + SGS +L +KR++ +LR + K + P N IRF
Sbjct: 414 NFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRF 459
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 140 bits (352), Expect = 4e-33
Identities = 102/346 (29%), Positives = 154/346 (44%), Gaps = 36/346 (10%)
Query: 39 PRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVC 97
P+LLPCLH+ C CL + E V I GG S G I Q+G++ CPVC
Sbjct: 140 PKLLPCLHSFCLRCLPEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVC 184
Query: 98 DA---QVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQTCKA 152
Q+DL +D+ V D S E VC C D C C
Sbjct: 185 RQECRQIDL---------VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGE 235
Query: 153 NLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCEFCDR 208
LC C +AH+R K T H + +D+ +G +P+ CPVH E+L+LFCE CDR
Sbjct: 236 WLCKTCIEAHQRVKFTKDHLIRKKEDVS--ESVGASGQRPVFCPVHKQEQLKLFCETCDR 293
Query: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
C+DC + EH+EH F ++ LL + A Q+ + +
Sbjct: 294 LTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNE 353
Query: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
+ V +++ I I + LL+QLE++ +++ L Q+ + L ++ +
Sbjct: 354 TNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVM 413
Query: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
FT + SGS +L +KR++ +LR + K + P N IRF
Sbjct: 414 NFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRF 459
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 138 bits (347), Expect = 2e-32
Identities = 117/470 (24%), Positives = 182/470 (38%), Gaps = 88/470 (18%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C +CL ++ P++LPCLHT C CL+ P
Sbjct: 22 CSICLDRYQCPKVLPCLHTFCERCLQNYIP----------------------------AQ 53
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQ 148
+ + CPVC LP GV AL N+ + SL Q
Sbjct: 54 SLTLSCPVCRQTSILPEQGVSALQ------NNFFISSLMEAMQ----------------- 90
Query: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDR 208
Q H D L + G+P+ CP H + + +CE C+
Sbjct: 91 ----------------QAPDGAHDPEDPHPLSVVA--GRPLSCPNHEGKTMEFYCEACET 132
Query: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
+C +C GEHREH +V+ +H ++ L+ + + L A+A + I+ LQ+
Sbjct: 133 AMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQE 192
Query: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
R A + E +A+++ + L+ LE I K+ LQ Q L Q + +
Sbjct: 193 RKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSC 252
Query: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEK--------- 379
F E L GS E+L+ ++ + ERL L + RP N ++ +
Sbjct: 253 SFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNL 312
Query: 380 ----AGQCRGYEIY----DLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKK 431
+E L +A Q AS T+ KD G ++ G ++ + D
Sbjct: 313 GALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGT 372
Query: 432 DSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRR 481
PV V D+K+GTY + YT + G + V + Q V+GSPF V R
Sbjct: 373 RLPV--PVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 420
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 138 bits (347), Expect = 2e-32
Identities = 117/470 (24%), Positives = 182/470 (38%), Gaps = 88/470 (18%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C +CL ++ P++LPCLHT C CL+ P
Sbjct: 22 CSICLDRYQCPKVLPCLHTFCERCLQNYIP----------------------------AQ 53
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQ 148
+ + CPVC LP GV AL N+ + SL Q
Sbjct: 54 SLTLSCPVCRQTSILPEQGVSALQ------NNFFISSLMEAMQ----------------- 90
Query: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDR 208
Q H D L + G+P+ CP H + + +CE C+
Sbjct: 91 ----------------QAPDGAHDPEDPHPLSVVA--GRPLSCPNHEGKTMEFYCEACET 132
Query: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
+C +C GEHREH +V+ +H ++ L+ + + L A+A + I+ LQ+
Sbjct: 133 AMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQE 192
Query: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
R A + E +A+++ + L+ LE I K+ LQ Q L Q + +
Sbjct: 193 RKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSC 252
Query: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEK--------- 379
F E L GS E+L+ ++ + ERL L + RP N ++ +
Sbjct: 253 SFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNL 312
Query: 380 ----AGQCRGYEIY----DLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKK 431
+E L +A Q AS T+ KD G ++ G ++ + D
Sbjct: 313 GALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGT 372
Query: 432 DSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRR 481
PV V D+K+GTY + YT + G + V + Q V+GSPF V R
Sbjct: 373 RLPV--PVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 420
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 133 bits (335), Expect = 4e-31
Identities = 111/470 (23%), Positives = 187/470 (39%), Gaps = 86/470 (18%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C +CL +K P++LPCLHT C CL+ P
Sbjct: 23 CSICLERYKNPKVLPCLHTFCERCLQNYIP----------------------------AH 54
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQ 148
+ + CPVC LP GV AL N+ + +L +V +R
Sbjct: 55 SLTLSCPVCRQTSILPEKGVAALQ------NNFFITNLM--------------DVLQRTP 94
Query: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDR 208
A ++ + T+ + GKP+ CP H + +C+ C+
Sbjct: 95 GSNA------------EESSILETVTAVA-------AGKPLSCPNHDGNVMEFYCQSCET 135
Query: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
+C++C GEH EHP +V+ +H S+ L + ++ AL I I L
Sbjct: 136 AMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTN 195
Query: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
+ ++ D+ + + K + + LL +LE K LQ Q L Q +++
Sbjct: 196 QKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCS 255
Query: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEKAGQCRGYEI 388
FT L G++ E+L+ K+ + E+L +L + P ND++ F + + + + +
Sbjct: 256 NFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNL 315
Query: 389 -----------------YDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKK 431
L + Q S T+ KD GE+ G N +
Sbjct: 316 GTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTG--NAYLTAELSTPD 373
Query: 432 DSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRR 481
S + DNK+GTY YT ++ G +T+ + + +QH++GSPF + V R
Sbjct: 374 GSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIR 423
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 133 bits (335), Expect = 4e-31
Identities = 111/470 (23%), Positives = 187/470 (39%), Gaps = 86/470 (18%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C +CL +K P++LPCLHT C CL+ P
Sbjct: 50 CSICLERYKNPKVLPCLHTFCERCLQNYIP----------------------------AH 81
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQ 148
+ + CPVC LP GV AL N+ + +L +V +R
Sbjct: 82 SLTLSCPVCRQTSILPEKGVAALQ------NNFFITNLM--------------DVLQRTP 121
Query: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDR 208
A ++ + T+ + GKP+ CP H + +C+ C+
Sbjct: 122 GSNA------------EESSILETVTAVA-------AGKPLSCPNHDGNVMEFYCQSCET 162
Query: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
+C++C GEH EHP +V+ +H S+ L + ++ AL I I L
Sbjct: 163 AMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTN 222
Query: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
+ ++ D+ + + K + + LL +LE K LQ Q L Q +++
Sbjct: 223 QKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCS 282
Query: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEKAGQCRGYEI 388
FT L G++ E+L+ K+ + E+L +L + P ND++ F + + + + +
Sbjct: 283 NFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNL 342
Query: 389 -----------------YDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKK 431
L + Q S T+ KD GE+ G N +
Sbjct: 343 GTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTG--NAYLTAELSTPD 400
Query: 432 DSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRR 481
S + DNK+GTY YT ++ G +T+ + + +QH++GSPF + V R
Sbjct: 401 GSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIR 450
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 128 bits (322), Expect = 1e-29
Identities = 96/350 (27%), Positives = 157/350 (44%), Gaps = 21/350 (6%)
Query: 37 KAPRLLPCLHTVCTTCLEQLEPFSVVDIRG-GDSDTS----SEGSIFQELKPRSLQSQIG 91
+AP+LLPCLH+ C CL + + ++ G ++T + GS P +Q+G
Sbjct: 66 RAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSP--FATQVG 123
Query: 92 IL-CPVCDAQVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQ 148
++ CPVC + + ID+ V D + S E VC C D E C
Sbjct: 124 VIRCPVCSQEC------AERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCV 177
Query: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCE 204
C LC C +AH+R K T HT V K+ +G +P+ CP H E+L+L+CE
Sbjct: 178 ECVEWLCKTCIRAHQRVKFTKDHT-VRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE 236
Query: 205 FCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINS 264
CD+ C+DC + EH+EH F + L+ + ++ QI
Sbjct: 237 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRII 296
Query: 265 ALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADM 324
+ + + V D++ + I + LL QLE + L Q+ ++ L +
Sbjct: 297 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL 356
Query: 325 RTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
+ F++ ++SGS +L +KR++ RLR L + + P N+ I+F
Sbjct: 357 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQF 406
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 128 bits (322), Expect = 1e-29
Identities = 96/350 (27%), Positives = 157/350 (44%), Gaps = 21/350 (6%)
Query: 37 KAPRLLPCLHTVCTTCLEQLEPFSVVDIRG-GDSDTS----SEGSIFQELKPRSLQSQIG 91
+AP+LLPCLH+ C CL + + ++ G ++T + GS P +Q+G
Sbjct: 66 RAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSP--FATQVG 123
Query: 92 IL-CPVCDAQVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQ 148
++ CPVC + + ID+ V D + S E VC C D E C
Sbjct: 124 VIRCPVCSQEC------AERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCV 177
Query: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCE 204
C LC C +AH+R K T HT V K+ +G +P+ CP H E+L+L+CE
Sbjct: 178 ECVEWLCKTCIRAHQRVKFTKDHT-VRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE 236
Query: 205 FCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINS 264
CD+ C+DC + EH+EH F + L+ + ++ QI
Sbjct: 237 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRII 296
Query: 265 ALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADM 324
+ + + V D++ + I + LL QLE + L Q+ ++ L +
Sbjct: 297 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL 356
Query: 325 RTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
+ F++ ++SGS +L +KR++ RLR L + + P N+ I+F
Sbjct: 357 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQF 406
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 122 bits (305), Expect = 1e-27
Identities = 91/354 (25%), Positives = 142/354 (40%), Gaps = 46/354 (12%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C +CL +AP+ LPCLHT C CL QL GG
Sbjct: 21 CKICLEQLRAPKTLPCLHTYCQDCLAQLAD-------GGR-------------------- 53
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQ----GLVCDLC------ 138
+ CP C V +P GV + + + L R G C LC
Sbjct: 54 ---VRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGT 110
Query: 139 -NDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKG-----YSRIGKPILCP 192
RC C +LC C HR ++T H +VDL + +R + CP
Sbjct: 111 STGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCP 170
Query: 193 VHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEAL 252
HP E LR C+ C + +C++C + H +HPC + + + LL G ++ L
Sbjct: 171 QHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVEL 230
Query: 253 EEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQL 312
E A + L+++ V V +EG ++A+ + ++L QL E + +
Sbjct: 231 EAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARE 290
Query: 313 QKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRP 366
+ A+LE R F +L+ G + EIL + + +RLR+L ++ P
Sbjct: 291 RLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGP 344
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 104 bits (259), Expect = 2e-22
Identities = 78/338 (23%), Positives = 138/338 (40%), Gaps = 28/338 (8%)
Query: 28 HCPLC---LGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPR 84
HC +C L + PRLLPCLH+ C+ CL P + GD + +G++
Sbjct: 64 HCGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANS--SGDGGAAGDGTVVD----- 116
Query: 85 SLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDRE-V 143
CPVC Q K + ++ + + + C C D
Sbjct: 117 ---------CPVCKQQCFS-----KDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPA 162
Query: 144 EKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG-KPILCPVHPAEELRLF 202
C C LC C +AH+R K T HT+ K SR G + + C VH E L LF
Sbjct: 163 TSYCVECSEPLCETCVEAHQRVKYTKDHTVRSTGPAK--SRDGERTVYCNVHKHEPLVLF 220
Query: 203 CEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHII 262
CE CD C+DC + H++H F + + + L+K L+++ ++
Sbjct: 221 CESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSS 280
Query: 263 NSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLA 322
+ + V DV+ +K + + L+ + + ++ L+ Q + ++
Sbjct: 281 IRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQK 340
Query: 323 DMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV 360
+ F L S ++ +L++K+++ +L + K+
Sbjct: 341 HQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKM 378
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 97.1 bits (240), Expect = 4e-20
Identities = 81/363 (22%), Positives = 152/363 (41%), Gaps = 33/363 (9%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQEL------- 81
CP C LF P +LPC H++C C+++L SD S++ S L
Sbjct: 33 CPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDK 92
Query: 82 ---------KPRSLQSQIGIL-CPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQ 131
K SL + + CP C+ VDL G+ L + + ++E R +
Sbjct: 93 IDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTL--ETIVERYRQAAR 150
Query: 132 G---LVCDLCND--REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG 186
++CDLC +E K C C A+ C+ C + H + T+ + G +
Sbjct: 151 AATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHH-----PWGTIKAQHEYVGPTTNF 205
Query: 187 KP--ILCPVHPAEELRLFCEFCDRPVCQDCVV-GEHREHPCDFTSNVIHKHGDSVWELLK 243
+P ++CP H E + ++CE C RPVC C + G H H S+ + + + +
Sbjct: 206 RPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDID 265
Query: 244 GTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIR 303
++ +++++++ + E + T E + +EE + +LK ++ +
Sbjct: 266 YLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSK 325
Query: 304 AQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYS 363
+ + Q Q + + LL + V + + +L + T + + R++K + S
Sbjct: 326 KLRLDKFQTQMEEYQGLLENNGL-VGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKS 384
Query: 364 TRP 366
RP
Sbjct: 385 FRP 387
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 84.0 bits (206), Expect = 3e-16
Identities = 79/372 (21%), Positives = 143/372 (38%), Gaps = 58/372 (15%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
CP+CL LF+ P LLPC H++C +C ++ S S G S++
Sbjct: 30 CPICLELFEDPLLLPCAHSLCFSCAHRILVSSC-----------SSGE--------SIEP 70
Query: 89 QIGILCPVCDAQVDLPMGGVKAL----TIDHLAVNDVMLESLRG---------------- 128
CP C + L G+ L T+ ++ ++ S+ G
Sbjct: 71 ITAFQCPTCRYVISLNHRGLDGLKRNVTLQNI-IDRFQKASVSGPNSPSESRRERTYRPT 129
Query: 129 ---EGQGLVCDLCND---REVEKRCQTCKANLCHFCCQA-HRRQKKTTYHTMVDL---KD 178
+ + C C R+ K C TC+ + C C +A H +K T H +V+
Sbjct: 130 TAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTH 189
Query: 179 LKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDC-VVGEHREHPCDFTSNVIHKHGDS 237
L+G I C H E++ ++C D+ +C C +VG HR+H ++ K +
Sbjct: 190 LRG-------ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQT 242
Query: 238 VWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLK 297
+ L LE +A++ I ++ A + + ++ I++ + +
Sbjct: 243 LEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAV 302
Query: 298 QLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKL 357
++++ + K L Q A Q L + EH+L L + + + ER+
Sbjct: 303 KIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMA 362
Query: 358 NKVQYSTRPGVN 369
P +N
Sbjct: 363 TASSQVLIPDIN 374
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 84.0 bits (206), Expect = 3e-16
Identities = 79/372 (21%), Positives = 143/372 (38%), Gaps = 58/372 (15%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
CP+CL LF+ P LLPC H++C +C ++ S S G S++
Sbjct: 30 CPICLELFEDPLLLPCAHSLCFSCAHRILVSSC-----------SSGE--------SIEP 70
Query: 89 QIGILCPVCDAQVDLPMGGVKAL----TIDHLAVNDVMLESLRG---------------- 128
CP C + L G+ L T+ ++ ++ S+ G
Sbjct: 71 ITAFQCPTCRYVISLNHRGLDGLKRNVTLQNI-IDRFQKASVSGPNSPSESRRERTYRPT 129
Query: 129 ---EGQGLVCDLCND---REVEKRCQTCKANLCHFCCQA-HRRQKKTTYHTMVDL---KD 178
+ + C C R+ K C TC+ + C C +A H +K T H +V+
Sbjct: 130 TAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTH 189
Query: 179 LKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDC-VVGEHREHPCDFTSNVIHKHGDS 237
L+G I C H E++ ++C D+ +C C +VG HR+H ++ K +
Sbjct: 190 LRG-------ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQT 242
Query: 238 VWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLK 297
+ L LE +A++ I ++ A + + ++ I++ + +
Sbjct: 243 LEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAV 302
Query: 298 QLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKL 357
++++ + K L Q A Q L + EH+L L + + + ER+
Sbjct: 303 KIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMA 362
Query: 358 NKVQYSTRPGVN 369
P +N
Sbjct: 363 TASSQVLIPDIN 374
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 80.1 bits (196), Expect = 5e-15
Identities = 69/353 (19%), Positives = 146/353 (41%), Gaps = 48/353 (13%)
Query: 28 HCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQ 87
+CP+C L +LPC H++C CL QL+ + V +
Sbjct: 145 NCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVT-----------------------E 181
Query: 88 SQIGILCPVCDAQVDLPMGGVKALTIDHL---AVNDVMLESL-------RGEGQGLVCDL 137
+ ++CPVCD +P L ++L M E R G ++C +
Sbjct: 182 NFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGP-ILCQV 240
Query: 138 CNDREVE-KRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPA 196
C +R + KRC TC+ NLC+ C +A H VD + +I C HP+
Sbjct: 241 CRNRRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKI-----CIHHPS 295
Query: 197 EELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEAL 256
+ +C ++ +C C H H + + S++ + + ++ L
Sbjct: 296 SRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDL 355
Query: 257 AQIHIINSALQKRVEAVAADVRTFSEGYIK---AIEEHRDKLLKQLEDIRAQKENSLQLQ 313
+ +I+ ++ + EA ++R G++K ++E +++Q+E++ ++ ++
Sbjct: 356 MEFNILKNSFKADKEAKRKEIR---NGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKY 412
Query: 314 KAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRP 366
+ +M + +++ L + L + +++V+++ + +Q + RP
Sbjct: 413 VYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIE--DGIQTTYRP 463
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 79.0 bits (193), Expect = 1e-14
Identities = 80/372 (21%), Positives = 147/372 (39%), Gaps = 58/372 (15%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
CP+CL LF+ P LLPC H++C C ++ + S++S
Sbjct: 10 CPICLELFEDPLLLPCAHSLCFNCAHRI-------------------LVSHCATNESVES 50
Query: 89 QIGILCPVCDAQVDLPMGGVKAL----TIDHLAVNDVMLESLRG---------------- 128
CP C + L G+ L T+ ++ ++ S+ G
Sbjct: 51 ITAFQCPTCRHVITLSQRGLDGLKRNVTLQNI-IDRFQKASVSGPNSPSETRRERAFDAN 109
Query: 129 ---EGQGLVCDLCND---REVEKRCQTCKANLCHFCCQA-HRRQKKTTYHTMVD-LKDLK 180
+ ++C C+ ++ K C TC+ + C C +A H +K T H +++ + D
Sbjct: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
Query: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDC-VVGEHREHPCDFTSNVIHKHGDSVW 239
S I + ++C H E++ ++C D+ +C C +VG HR+H S K ++
Sbjct: 168 --SHI-RGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLE 224
Query: 240 ELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEG--YIKAIEEHRDKLLK 297
L LE LA+ +I + V A + + E I+ I++ R +
Sbjct: 225 SNLTNLIKRNTELETLLAK--LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGT 282
Query: 298 QLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKL 357
++++ + + L Q A +Q + + + EH L L T + + ER+
Sbjct: 283 KIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMA 342
Query: 358 NKVQYSTRPGVN 369
P +N
Sbjct: 343 TASSQVLIPEIN 354
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 79.0 bits (193), Expect = 1e-14
Identities = 80/372 (21%), Positives = 147/372 (39%), Gaps = 58/372 (15%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
CP+CL LF+ P LLPC H++C C ++ + S++S
Sbjct: 10 CPICLELFEDPLLLPCAHSLCFNCAHRI-------------------LVSHCATNESVES 50
Query: 89 QIGILCPVCDAQVDLPMGGVKAL----TIDHLAVNDVMLESLRG---------------- 128
CP C + L G+ L T+ ++ ++ S+ G
Sbjct: 51 ITAFQCPTCRHVITLSQRGLDGLKRNVTLQNI-IDRFQKASVSGPNSPSETRRERAFDAN 109
Query: 129 ---EGQGLVCDLCND---REVEKRCQTCKANLCHFCCQA-HRRQKKTTYHTMVD-LKDLK 180
+ ++C C+ ++ K C TC+ + C C +A H +K T H +++ + D
Sbjct: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
Query: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDC-VVGEHREHPCDFTSNVIHKHGDSVW 239
S I + ++C H E++ ++C D+ +C C +VG HR+H S K ++
Sbjct: 168 --SHI-RGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLE 224
Query: 240 ELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEG--YIKAIEEHRDKLLK 297
L LE LA+ +I + V A + + E I+ I++ R +
Sbjct: 225 SNLTNLIKRNTELETLLAK--LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGT 282
Query: 298 QLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKL 357
++++ + + L Q A +Q + + + EH L L T + + ER+
Sbjct: 283 KIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMA 342
Query: 358 NKVQYSTRPGVN 369
P +N
Sbjct: 343 TASSQVLIPEIN 354
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 79.0 bits (193), Expect = 1e-14
Identities = 80/372 (21%), Positives = 147/372 (39%), Gaps = 58/372 (15%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
CP+CL LF+ P LLPC H++C C ++ + S++S
Sbjct: 10 CPICLELFEDPLLLPCAHSLCFNCAHRI-------------------LVSHCATNESVES 50
Query: 89 QIGILCPVCDAQVDLPMGGVKAL----TIDHLAVNDVMLESLRG---------------- 128
CP C + L G+ L T+ ++ ++ S+ G
Sbjct: 51 ITAFQCPTCRHVITLSQRGLDGLKRNVTLQNI-IDRFQKASVSGPNSPSETRRERAFDAN 109
Query: 129 ---EGQGLVCDLCND---REVEKRCQTCKANLCHFCCQA-HRRQKKTTYHTMVD-LKDLK 180
+ ++C C+ ++ K C TC+ + C C +A H +K T H +++ + D
Sbjct: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
Query: 181 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDC-VVGEHREHPCDFTSNVIHKHGDSVW 239
S I + ++C H E++ ++C D+ +C C +VG HR+H S K ++
Sbjct: 168 --SHI-RGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLE 224
Query: 240 ELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEG--YIKAIEEHRDKLLK 297
L LE LA+ +I + V A + + E I+ I++ R +
Sbjct: 225 SNLTNLIKRNTELETLLAK--LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGT 282
Query: 298 QLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKL 357
++++ + + L Q A +Q + + + EH L L T + + ER+
Sbjct: 283 KIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMA 342
Query: 358 NKVQYSTRPGVN 369
P +N
Sbjct: 343 TASSQVLIPEIN 354
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 78.2 bits (191), Expect = 2e-14
Identities = 98/398 (24%), Positives = 153/398 (38%), Gaps = 71/398 (17%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGD--SDTSSEGSIFQELKPRS- 85
CP+C ++K P +LPC H VC C ++ GGD S+ +S S PR
Sbjct: 33 CPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLS 92
Query: 86 -------------LQSQIGIL----------------CPVCDAQVDLPMGGVKALTIDHL 116
L+S G CP C V+L G+ L +L
Sbjct: 93 RRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGL-FRNL 151
Query: 117 AVNDVMLESLRGE---GQGLVCDLCNDREVE--KRCQTCKANLCHFCCQ------AHRRQ 165
+ V+ E R G ++C LC +E K C C+A C+ C + + Q
Sbjct: 152 TLERVV-ERYRQSVSVGGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQ 210
Query: 166 KKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGE-HREHPC 224
+ T T+ S K ++CP H EE+ +C+ C R VCQ C V H H
Sbjct: 211 HEPTLPTL---------SFRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKI 260
Query: 225 DFTSNVIHKHGDSVWELLK---GTQPHVEA----LEEALAQIHIINSALQKRVEAVAADV 277
+ D + + L G Q V+ LEEA+ + Q+ E V+ V
Sbjct: 261 TPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSG---QQAKEEVSQLV 317
Query: 278 RTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTS 337
R G +EE R LL+ +E+ + ++ L Q Q + L D V + + +L
Sbjct: 318 R----GLGAVLEEKRASLLQAIEECQQERLARLSAQ-IQEHRSLLDGSGLVGYAQEVLKE 372
Query: 338 GSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFC 375
+ + + R+ + + + RP + R C
Sbjct: 373 TDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHC 410
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 77.8 bits (190), Expect = 2e-14
Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 26/255 (10%)
Query: 135 CDLCND-REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKP----- 188
C C + R C C LC C + HR H+ V ++ G P
Sbjct: 5 CSECKEKRAAHILCTYCNRWLCSSCTEEHR-------HSPVPGGPFFPRAQKGSPGVNGG 57
Query: 189 -----ILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLK 243
+ CP+H E L+LFCE CD C C+V EH+EH C V+ LL+
Sbjct: 58 PGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQR----MLLE 113
Query: 244 GTQPHV----EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQL 299
G V +L+ + QI ++ + V ++ + + + + L+++L
Sbjct: 114 GVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEEL 173
Query: 300 EDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNK 359
E I +++ L+ Q + L F + S + + L +K ++V ++++L +
Sbjct: 174 EGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLE 233
Query: 360 VQYSTRPGVNDKIRF 374
+T PG IRF
Sbjct: 234 TSCNTDPGSPWSIRF 248
>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
sapiens]
Length = 781
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
Length = 611
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
Length = 829
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
Length = 435
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
Length = 633
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
Length = 423
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
sapiens]
Length = 585
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
Length = 882
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)
Query: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88
C C K P+LLPCLHT+C+ CLE
Sbjct: 57 CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
Query: 89 QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140
G+ CP+C Q P+G D A+++V ESL+ VC C +
Sbjct: 85 --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
Query: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192
+ C C+ LC C +AH+ K + +L++ L G +R I C P
Sbjct: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
Query: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249
H L ++C C +P+C C + H E CD ++ + + E L +
Sbjct: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
Query: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306
+ + A +H A ++ A+ ++ + H +++ L + D R Q+
Sbjct: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
Query: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344
+ + + +L+ +L +RTG + + SD E+L
Sbjct: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,860,472
Number of Sequences: 37866
Number of extensions: 1192712
Number of successful extensions: 4651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 4105
Number of HSP's gapped (non-prelim): 560
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.