Search of human proteins with 224465184

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
         (554 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]             1149   0.0  
gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]             1049   0.0  
gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]             1030   0.0  
gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]               974   0.0  
gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact...   602   e-172
gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]               575   e-164
gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]               512   e-145
gi|93004092 nuclear factor I/B [Homo sapiens]                         502   e-142
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             62   2e-09
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    59   2e-08
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    59   2e-08
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    59   2e-08
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    59   2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    55   2e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          52   1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          52   1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          52   1e-06
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             52   2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   2e-06
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 51   2e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 51   2e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 51   2e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    51   3e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is...    50   4e-06
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        50   5e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   50   7e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   50   7e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   50   7e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    50   7e-06
gi|50345997 E1A binding protein p300 [Homo sapiens]                    49   9e-06

>gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
          Length = 554

 Score = 1149 bits (2972), Expect = 0.0
 Identities = 554/554 (100%), Positives = 554/554 (100%)

Query: 1   MQMCRPASSSVLYVPTRWPGGCGATWQSCPSPPPRRTRIPQRPAVMYSPLCLTQDEFHPF 60
           MQMCRPASSSVLYVPTRWPGGCGATWQSCPSPPPRRTRIPQRPAVMYSPLCLTQDEFHPF
Sbjct: 1   MQMCRPASSSVLYVPTRWPGGCGATWQSCPSPPPRRTRIPQRPAVMYSPLCLTQDEFHPF 60

Query: 61  IEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRL 120
           IEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRL
Sbjct: 61  IEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRL 120

Query: 121 LAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVI 180
           LAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVI
Sbjct: 121 LAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVI 180

Query: 181 LFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPS 240
           LFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPS
Sbjct: 181 LFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPS 240

Query: 241 QPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYY 300
           QPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYY
Sbjct: 241 QPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYY 300

Query: 301 SMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEP 360
           SMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEP
Sbjct: 301 SMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEP 360

Query: 361 GMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPI 420
           GMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPI
Sbjct: 361 GMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPI 420

Query: 421 IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP 480
           IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP
Sbjct: 421 IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP 480

Query: 481 MLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPS 540
           MLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPS
Sbjct: 481 MLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPS 540

Query: 541 FVNIPQQTQSWYLG 554
           FVNIPQQTQSWYLG
Sbjct: 541 FVNIPQQTQSWYLG 554


>gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]
          Length = 509

 Score = 1049 bits (2713), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 46  MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 105
           MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL
Sbjct: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60

Query: 106 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 165
           LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL
Sbjct: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120

Query: 166 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 225
           RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA
Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180

Query: 226 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285
           YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT
Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240

Query: 286 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 345
           GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS
Sbjct: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300

Query: 346 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 405
           PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS
Sbjct: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360

Query: 406 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 465
           PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN
Sbjct: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420

Query: 466 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 525
           GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480

Query: 526 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 554
           SPANRFVSVGPRDPSFVNIPQQTQSWYLG
Sbjct: 481 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 509


>gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
          Length = 501

 Score = 1030 bits (2663), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 55  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 114
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ
Sbjct: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61

Query: 115 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 174
           KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 62  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121

Query: 175 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 234
           DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS
Sbjct: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181

Query: 235 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 294
           QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL
Sbjct: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241

Query: 295 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 354
           ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG
Sbjct: 242 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 301

Query: 355 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 414
           WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH
Sbjct: 302 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361

Query: 415 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 474
           FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN
Sbjct: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421

Query: 475 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 534
           PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV
Sbjct: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481

Query: 535 GPRDPSFVNIPQQTQSWYLG 554
           GPRDPSFVNIPQQTQSWYLG
Sbjct: 482 GPRDPSFVNIPQQTQSWYLG 501


>gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
          Length = 498

 Score =  974 bits (2519), Expect = 0.0
 Identities = 477/494 (96%), Positives = 478/494 (96%)

Query: 46  MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 105
           MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL
Sbjct: 1   MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60

Query: 106 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 165
           LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL
Sbjct: 61  LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120

Query: 166 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 225
           RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA
Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180

Query: 226 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285
           YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT
Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240

Query: 286 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 345
           GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS
Sbjct: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300

Query: 346 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 405
           PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS
Sbjct: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360

Query: 406 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 465
           PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN
Sbjct: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420

Query: 466 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 525
           GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP       
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 480

Query: 526 SPANRFVSVGPRDP 539
             A+      P DP
Sbjct: 481 VAASHHPPDRPPDP 494


>gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor)
           [Homo sapiens]
          Length = 441

 Score =  602 bits (1553), Expect = e-172
 Identities = 311/422 (73%), Positives = 350/422 (82%), Gaps = 13/422 (3%)

Query: 46  MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 105
           MYSP CLTQDEFHPFIEALLPHVRAF+YTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL
Sbjct: 1   MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 60

Query: 106 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 165
           L EKPE+KQKWASRLLAKLRKDIRPE+REDFVLT+TGKKPPCCVLSNPDQKGK+RRIDCL
Sbjct: 61  LGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCL 120

Query: 166 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 225
           RQADKVWRLDLVMVILFKGIPLESTDGERL KSPQCSNPGLCVQPHHIGV++KELDLYLA
Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLA 180

Query: 226 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285
           YFVH  +S QS+S +Q  DADIK  P NGHL FQD FVTSGV++VTELVRVSQTP+A  +
Sbjct: 181 YFVHTPESGQSDSSNQQGDADIKPLP-NGHLSFQDCFVTSGVWNVTELVRVSQTPVATAS 239

Query: 286 GPNFSLSDLESSSYYSMSPGAM-RRSLPSTSSTSSTKRLKSVED-EMDSPGEEPFYTGQG 343
           GPNFSL+DLES SYY+++   + RRS+ S  STS+TKR KS++D EM+SP ++ FY G G
Sbjct: 240 GPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTG 299

Query: 344 RSPGSG-SQSSGW-HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG 401
           RSP +G SQSSGW ++V+ G   P +LKKS K  F S   SQ SS   AFT H  PV+ G
Sbjct: 300 RSPAAGSSQSSGWPNDVDAG---PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAG 356

Query: 402 PR-ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRY---HPQETLKEFVQLVCPD-AGQQA 456
            R  SP AT S LHFP++ IIQQ  PYF+HP IRY   H Q++LKEFVQ VC D +GQ  
Sbjct: 357 VRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQAT 416

Query: 457 GQ 458
           GQ
Sbjct: 417 GQ 418


>gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
          Length = 499

 Score =  575 bits (1483), Expect = e-164
 Identities = 324/518 (62%), Positives = 378/518 (72%), Gaps = 38/518 (7%)

Query: 55  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 114
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61

Query: 115 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 174
           KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121

Query: 175 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 234
           DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+ 
Sbjct: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181

Query: 235 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 292
           QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL 
Sbjct: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241

Query: 293 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 349
           +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S 
Sbjct: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 297

Query: 350 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 404
           + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G   
Sbjct: 298 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 356

Query: 405 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 459
           SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G +
Sbjct: 357 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415

Query: 460 GFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPTS 517
                NGS Q K+ +  L   ML PPPP  P +A P     P TKP TTS EGGA SPTS
Sbjct: 416 -----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPTS 464

Query: 518 PTYSTPSTSPANR-FVSVGPRDPSFVNIPQQTQSWYLG 554
           P+YS P TSPANR FV +GPRDP+ +    Q QSWYLG
Sbjct: 465 PSYSPPDTSPANRSFVGLGPRDPAGI---YQAQSWYLG 499


>gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]
          Length = 428

 Score =  512 bits (1318), Expect = e-145
 Identities = 278/430 (64%), Positives = 325/430 (75%), Gaps = 21/430 (4%)

Query: 48  SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLS 107
           SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL 
Sbjct: 4   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63

Query: 108 EKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQ 167
           EKPEVKQKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQ
Sbjct: 64  EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123

Query: 168 ADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYF 227
           ADKVWRLDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYF
Sbjct: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183

Query: 228 VHAADSSQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285
           V   D+ QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GT
Sbjct: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243

Query: 286 GPNFSLSDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQ 342
           GPNFSL +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT  
Sbjct: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT-- 301

Query: 343 GRSPGSGSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI- 399
             SP S + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI 
Sbjct: 302 --SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIA 358

Query: 400 --TGPRASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 452
             +G   SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A
Sbjct: 359 VHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 417

Query: 453 GQQAGQVGFL 462
            QQ G   +L
Sbjct: 418 SQQPGPSWYL 427


>gi|93004092 nuclear factor I/B [Homo sapiens]
          Length = 420

 Score =  502 bits (1293), Expect = e-142
 Identities = 274/422 (64%), Positives = 314/422 (74%), Gaps = 22/422 (5%)

Query: 45  VMYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDE 104
           +MYSP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDE
Sbjct: 1   MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60

Query: 105 LLSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDC 164
           LLSEKPE+KQKWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDC
Sbjct: 61  LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC 120

Query: 165 LRQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYL 224
           LRQADKVWRLDLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+L
Sbjct: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL 180

Query: 225 AYFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAG 284
           AY+V   DS QS SPS    A  K+ P  G+L  +DSFV SGVF+V+ELVRVS+TPI  G
Sbjct: 181 AYYVQEQDSGQSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQG 234

Query: 285 TGPNFSLSDLESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQ 342
           TG NF + ++ S  YY  M+ G  ++RSL S  S+   K + S+++ M+      FY   
Sbjct: 235 TGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSP 293

Query: 343 GRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGP 402
             SP +GS++  WHE +  M SPTT+KK EK  FSS SP  +S   + F QHH P I G 
Sbjct: 294 S-SPAAGSRT--WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGV 350

Query: 403 RASPHAT-----PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 452
             S  +T     PS L FPT  I+   P  YFSHP IRY    +PQ+TLK +V    P +
Sbjct: 351 AHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSS 410

Query: 453 GQ 454
            Q
Sbjct: 411 PQ 412


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 98/366 (26%), Positives = 132/366 (36%), Gaps = 26/366 (7%)

Query: 186  PLESTDGERLVKSPQCSNPGLCVQPHHIGVSV----KELDLYLAYFVHAADSSQSESPSQ 241
            P   + G     SP   +PG  + P +   S     +    Y       + +S S SP+ 
Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626

Query: 242  PSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYS 301
            PS +            +     TS  +S T       +P  + T P++S +   S SY  
Sbjct: 1627 PSYSPTSPNYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPT---SPSYSP 1680

Query: 302  MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 361
             SP     S PS S TS +    S      SP   P  T    SP S S S       P 
Sbjct: 1681 TSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPT 1737

Query: 362  MPS--PTTLKKSEKSGF---SSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFP 416
             PS  PT+   S  S     +SPS S TS   +  + ++ P  T P  SP  +PS  + P
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTP--TSPNYSP-TSPS--YSP 1792

Query: 417  TSPIIQQPGPYFSHPAIRYHPQE-TLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 475
            TSP      P +S  + RY PQ  T         P +   +       P   S       
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852

Query: 476  FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 535
            + PT     P  P  +   P   P +  PT S      SPTSPTYS  S           
Sbjct: 1853 YTPTSPKYSPTSPKYSPTSPKYSPTS--PTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYS 1910

Query: 536  PRDPSF 541
            P  P++
Sbjct: 1911 PTSPTY 1916



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 85/307 (27%), Positives = 111/307 (36%), Gaps = 37/307 (12%)

Query: 233  SSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 292
            +S S SP+ PS +            +     TS  +S T       +P  + T PN+S +
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1751

Query: 293  DLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 352
               S +Y   SP     S PS S TS      S      SP   P  T    SP S S S
Sbjct: 1752 ---SPNYTPTSPSYSPTS-PSYSPTSPNYTPTSPNYSPTSPSYSP--TSPSYSPTSPSYS 1805

Query: 353  SGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPST 412
                   P   SPT    S     SSPS S TS   T  +  + P      +SP  TP++
Sbjct: 1806 PSSPRYTP--QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSP------SSPEYTPTS 1857

Query: 413  LHF-PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 471
              + PTSP      P +S  +  Y P                    +    +P  S    
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTP-----------------KYSPTSPTYSPTSP 1900

Query: 472  VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRF 531
            V+ P  P    P  P      P   P   T  PT S +G   SPTSP YS  S + +   
Sbjct: 1901 VYTPTSPK-YSPTSPTYSPTSPKYSPTSPTYSPT-SPKGSTYSPTSPGYSPTSPTYSLTS 1958

Query: 532  VSVGPRD 538
             ++ P D
Sbjct: 1959 PAISPDD 1965



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 70/265 (26%), Positives = 97/265 (36%), Gaps = 39/265 (14%)

Query: 277  SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEE 336
            + TP   G  P +        S   M+PGA   S PS +S +S            SPG  
Sbjct: 1516 AMTPWNQGATPAYGAWSPSVGS--GMTPGAAGFS-PSAASDASGF----------SPGYS 1562

Query: 337  PFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHR 396
            P ++    SPGS   SS      P +PSP         G  SPS S TS       +   
Sbjct: 1563 PAWSPTPGSPGSPGPSS------PYIPSP--------GGAMSPSYSPTSPA----YEPRS 1604

Query: 397  PVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 456
            P    P++  ++  S  + PTSP      P +S  +  Y P            P +   +
Sbjct: 1605 PGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS------PTSPSYS 1658

Query: 457  GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPT 516
                  +P   S       + PT     P  P  +   P   P +  P+ S    + SPT
Sbjct: 1659 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPT 1716

Query: 517  SPTYSTPSTSPANRFVSVGPRDPSF 541
            SP+YS  S S +    S  P  PS+
Sbjct: 1717 SPSYSPTSPSYSPTSPSYSPTSPSY 1741



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 72/273 (26%), Positives = 98/273 (35%), Gaps = 39/273 (14%)

Query: 283  AGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRL-KSVEDEMD--SPGEEPFY 339
            AGTG    L D E   Y    P     ++P   +   T     S    M   SP   P+ 
Sbjct: 1466 AGTGCFDLLLDAEKCKYGMEIP----TNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWN 1521

Query: 340  TGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS-------SPSPSQTSSLGTAFT 392
             G   + G+ S S G   + PG    +    S+ SGFS       SP+P    S G +  
Sbjct: 1522 QGATPAYGAWSPSVG-SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPS-- 1578

Query: 393  QHHRPVITGPRASPHATPSTLHFPTSPIIQ--QPGPYFSHPAIRYHPQETLKEFVQLVCP 450
                P I     SP    S  + PTSP  +   PG Y +  +  Y P            P
Sbjct: 1579 ---SPYIP----SPGGAMSPSYSPTSPAYEPRSPGGY-TPQSPSYSPTS----------P 1620

Query: 451  DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP--PTTST 508
                 +      +PN S     ++P  P+     P   P +       P   P  P+ S 
Sbjct: 1621 SYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1680

Query: 509  EGGAASPTSPTYSTPSTSPANRFVSVGPRDPSF 541
               + SPTSP+YS  S S +    S  P  PS+
Sbjct: 1681 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1713



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 54/197 (27%), Positives = 75/197 (38%), Gaps = 23/197 (11%)

Query: 264  TSGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPGAMRRSLPSTSSTSST 320
            TS  +S T       +P  + T P++S S       S  Y+ S  +   S PS S TS  
Sbjct: 1779 TSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPK 1838

Query: 321  KRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMP--SPTTLKKSEKSGFSS 378
                S      SP   P  T    SP S   S    +  P  P  SPTT K S     +S
Sbjct: 1839 YTPTSPSYSPSSPEYTP--TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSP----TS 1892

Query: 379  PSPSQTSSLGTAFTQHHRPVI------------TGPRASPHATPSTLHFPTSPIIQQPGP 426
            P+ S TS + T  +  + P              T P  SP +   + + PTSP      P
Sbjct: 1893 PTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSP 1952

Query: 427  YFSHPAIRYHPQETLKE 443
             +S  +    P ++ +E
Sbjct: 1953 TYSLTSPAISPDDSDEE 1969


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)

Query: 379 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 438
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 439 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 498
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 499 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 542
           P  +P +  T    A P S  + TPST+P      + P  PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)

Query: 460 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 507
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 508 TEGGAASPTSP 518
                A P  P
Sbjct: 362 ALQAPAVPPPP 372



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 17/51 (33%), Positives = 21/51 (41%)

Query: 478 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 528
           P  + P PPPPP   P  L     +   TST      P  P  +T   +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)

Query: 484 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
           PPPPPPM     A+P+P  +        +     A+  +P + +P+  P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)

Query: 379 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 438
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 439 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 498
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 499 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 542
           P  +P +  T    A P S  + TPST+P      + P  PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)

Query: 460 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 507
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 508 TEGGAASPTSP 518
                A P  P
Sbjct: 362 ALQAPAVPPPP 372



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 17/51 (33%), Positives = 21/51 (41%)

Query: 478 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 528
           P  + P PPPPP   P  L     +   TST      P  P  +T   +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)

Query: 484 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
           PPPPPPM     A+P+P  +        +     A+  +P + +P+  P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)

Query: 379 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 438
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 439 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 498
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 499 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 542
           P  +P +  T    A P S  + TPST+P      + P  PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)

Query: 460 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 507
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 508 TEGGAASPTSP 518
                A P  P
Sbjct: 362 ALQAPAVPPPP 372



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 17/51 (33%), Positives = 21/51 (41%)

Query: 478 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 528
           P  + P PPPPP   P  L     +   TST      P  P  +T   +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)

Query: 484 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
           PPPPPPM     A+P+P  +        +     A+  +P + +P+  P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%)

Query: 379 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 438
           PS   TSSL  + T    P +  P   P         P  P   Q  P   HPA    P 
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387

Query: 439 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 498
                 VQ   P   + A     +  +   QG+V         LPPPPPPP     PLP 
Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434

Query: 499 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 542
           P  +P +  T    A P S  + TPST+P      + P  PS V
Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%)

Query: 460 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 507
           G +     S      P   +P  PPPPPP             M    P PVP   PP  +
Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361

Query: 508 TEGGAASPTSP 518
                A P  P
Sbjct: 362 ALQAPAVPPPP 372



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 17/51 (33%), Positives = 21/51 (41%)

Query: 478 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 528
           P  + P PPPPP   P  L     +   TST      P  P  +T   +PA
Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%)

Query: 484 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
           PPPPPPM     A+P+P  +        +     A+  +P + +P+  P
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 75/301 (24%), Positives = 103/301 (34%), Gaps = 61/301 (20%)

Query: 277 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 335
           S  P     GP  S+S     S    SP A RR S        +++ L S    + SP  
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245

Query: 336 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPT------TLKKSEKSGFSSPSPSQ--- 383
             P   G  R+P   SQ    G   + P   +P        L     S  ++PSPS    
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305

Query: 384 ---------------------TSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 422
                                T+SLG+   Q     +  P  SP ATP     P +P   
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAP--- 358

Query: 423 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 482
              P  + P ++  P            P A      +   +P   +   VH   L  P  
Sbjct: 359 ---PALALPPLQAPPS-----------PPASPPLSPLATPSPQAPNALAVH--LLQAPFS 402

Query: 483 PPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRD 538
           PPP PP   P + P   PV P   PP+ +    AA P     S P++ P +   +  P+ 
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462

Query: 539 P 539
           P
Sbjct: 463 P 463



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 59/255 (23%), Positives = 93/255 (36%), Gaps = 34/255 (13%)

Query: 295 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 351
           E+    ++S GA R +    P T S +  +R ++   E+  P   P    +  + G    
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199

Query: 352 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 410
            S   E     PSP   ++ S   G   P+    SS  T  +    P  +GP A    TP
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS---PARSGPSA--RGTP 254

Query: 411 STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 470
                P+ P  +  G     P     PQ T         P     A  +G L+ +  +  
Sbjct: 255 RAPAHPSQP--KPKGLQALRP-----PQVT---------PPRKDAAPALGPLSSSPLAT- 297

Query: 471 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANR 530
                  P+P  PP P  P +    LP P   PP+ +T    +     T+S   + P + 
Sbjct: 298 -------PSPSAPPSPSAPPSLQT-LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349

Query: 531 FVSVGPRDPSFVNIP 545
             +  P+ P  + +P
Sbjct: 350 LATPPPQAPPALALP 364



 Score = 36.2 bits (82), Expect = 0.081
 Identities = 62/259 (23%), Positives = 88/259 (33%), Gaps = 47/259 (18%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 362
           SP A   S  +TS  S T  L++    + SP   P  T   ++P + +       + P  
Sbjct: 317 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 367

Query: 363 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 410
             P+       S  ++PSP   ++L        F+    P +         P  SP ATP
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427

Query: 411 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 454
            +          L  P SP    P       P  + P +   P +  K   Q   P A  
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 485

Query: 455 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPPPPPMARPVPLPVPDTKPPTTST 508
                   +P  S  G+   PF P+  LP      PPP  P     PL      PP + T
Sbjct: 486 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543

Query: 509 EGGAASPTSPTYSTPSTSP 527
                 P +P   T  + P
Sbjct: 544 LQAPRRPPTPGPDTSVSGP 562



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 36/195 (18%)

Query: 377 SSPSPSQTSSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQQPG---PYFSHPA 432
           + P P    +L T   Q    P  + P  +P +  ++L  P SP+   P    P  + P 
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPL 531

Query: 433 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMAR 492
           ++  P       +Q     A ++        P       V  P L   + P PPPPP   
Sbjct: 532 LQVPPSPPASPTLQ-----APRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRS 579

Query: 493 P-VPLPVPDTKPPTTST--------------EGGAASPTSPTYSTPSTSPANRFVSVGPR 537
           P   L  PD    ++S               EGGAA+   P     +  PA    S GP 
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPA 637

Query: 538 DP-SFVNIPQQTQSW 551
            P +F   P     W
Sbjct: 638 PPLAFRGAPGAPLPW 652


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%)

Query: 270 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 327
           + E +R S   +P AA T  N S ++    S   +   A   S P  S+    +++ S  
Sbjct: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 104

Query: 328 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 381
           +E D    +   T +   P S S+  G         + G   P  + +  +S   S PSP
Sbjct: 105 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 164

Query: 382 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 433
                   SS      Q   P +   TG   +P + P     P +P +  PGP  S  A+
Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 219

Query: 434 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 493
              PQ +         P A Q   Q     P   +    H      P L P  PP    P
Sbjct: 220 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 260

Query: 494 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
            P P P   PP     G A  P++P+++ P
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 290



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%)

Query: 336 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 381
           +P   GQG  PG  S  +G     PG P P  L      G +    SP+          P
Sbjct: 289 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347

Query: 382 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 440
           +  S+L +      +P+   P A PH  P     PT+PI Q P P    HP     P   
Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 403

Query: 441 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 487
                 L  P A +    +   +P  +    +       P   +P  PP        PPP
Sbjct: 404 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462

Query: 488 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 536
           P    P  L     +PP        GG    T PT  + ST PA    S  P
Sbjct: 463 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%)

Query: 287 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 346
           P  + SD +SS+   M           T  T +         ++ +PG  P  T     P
Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 220

Query: 347 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 395
             GS ++     +P  P+           P    +   S    P PS            H
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 269

Query: 396 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 447
            P+  +TG    P A  HA P  LH   P  P   Q GP   HP     P +        
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 319

Query: 448 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 503
           + P A Q    +G       P+ S Q       L +   P   P P   P PL +P  KP
Sbjct: 320 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 376

Query: 504 PTTSTEGGAASPTS----PTYSTPSTSPAN 529
           P T+      +P +    P  S PS    N
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%)

Query: 270 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 327
           + E +R S   +P AA T  N S ++    S   +   A   S P  S+    +++ S  
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658

Query: 328 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 381
           +E D    +   T +   P S S+  G         + G   P  + +  +S   S PSP
Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718

Query: 382 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 433
                   SS      Q   P +   TG   +P + P     P +P +  PGP  S  A+
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773

Query: 434 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 493
              PQ +         P A Q   Q     P   +    H      P L P  PP    P
Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814

Query: 494 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
            P P P   PP     G A  P++P+++ P
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 844



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%)

Query: 336  EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 381
            +P   GQG  PG  S  +G     PG P P  L      G +    SP+          P
Sbjct: 843  QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901

Query: 382  SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 440
            +  S+L +      +P+   P A PH  P     PT+PI Q P P    HP     P   
Sbjct: 902  ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957

Query: 441  LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 487
                  L  P A +    +   +P  +    +       P   +P  PP        PPP
Sbjct: 958  SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016

Query: 488  PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 536
            P    P  L     +PP        GG    T PT  + ST PA    S  P
Sbjct: 1017 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%)

Query: 287 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 346
           P  + SD +SS+   M           T  T +         ++ +PG  P  T     P
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774

Query: 347 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 395
             GS ++     +P  P+           P    +   S    P PS            H
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 823

Query: 396 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 447
            P+  +TG    P A  HA P  LH   P  P   Q GP   HP     P +        
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 873

Query: 448 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 503
           + P A Q    +G       P+ S Q       L +   P   P P   P PL +P  KP
Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 930

Query: 504 PTTSTEGGAASPTS----PTYSTPSTSPAN 529
           P T+      +P +    P  S PS    N
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%)

Query: 270 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 327
           + E +R S   +P AA T  N S ++    S   +   A   S P  S+    +++ S  
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658

Query: 328 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 381
           +E D    +   T +   P S S+  G         + G   P  + +  +S   S PSP
Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718

Query: 382 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 433
                   SS      Q   P +   TG   +P + P     P +P +  PGP  S  A+
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773

Query: 434 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 493
              PQ +         P A Q   Q     P   +    H      P L P  PP    P
Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814

Query: 494 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
            P P P   PP     G A  P++P+++ P
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 844



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%)

Query: 336  EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 381
            +P   GQG  PG  S  +G     PG P P  L      G +    SP+          P
Sbjct: 843  QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901

Query: 382  SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 440
            +  S+L +      +P+   P A PH  P     PT+PI Q P P    HP     P   
Sbjct: 902  ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957

Query: 441  LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 487
                  L  P A +    +   +P  +    +       P   +P  PP        PPP
Sbjct: 958  SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016

Query: 488  PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 536
            P    P  L     +PP        GG    T PT  + ST PA    S  P
Sbjct: 1017 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%)

Query: 287 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 346
           P  + SD +SS+   M           T  T +         ++ +PG  P  T     P
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774

Query: 347 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 395
             GS ++     +P  P+           P    +   S    P PS            H
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 823

Query: 396 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 447
            P+  +TG    P A  HA P  LH   P  P   Q GP   HP     P +        
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 873

Query: 448 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 503
           + P A Q    +G       P+ S Q       L +   P   P P   P PL +P  KP
Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 930

Query: 504 PTTSTEGGAASPTS----PTYSTPSTSPAN 529
           P T+      +P +    P  S PS    N
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 61/262 (23%), Positives = 93/262 (35%), Gaps = 28/262 (10%)

Query: 285  TGPNFSLSDLESSSYYSMSPGAMRRSLPS-----TSSTSSTKRLKSVEDEMDSPGEEPFY 339
            T P+F+LS  +SS   +++P      LP+     TS  S+   + S+    +   E    
Sbjct: 1065 TSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTT 1124

Query: 340  TGQGRSPGSGSQSSGWHEVEPG-MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 398
                 +P S + S      +P   P PTT          + +P   ++L    T H  P 
Sbjct: 1125 PDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDP------TMAPDPITTLNPTVTPHF-PT 1177

Query: 399  ITGPRASPHATPST--LHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 456
               P  +PH T  T     P      QP    +H  +   P  T + F  +         
Sbjct: 1178 TPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237

Query: 457  GQVGFLNPNGSSQGKVHNPFLPTPMLPPPP---------PPPMARPVPL--PVPDTKPPT 505
                   P+ ++    H+  +P P   P P         P P   P P   P P T P  
Sbjct: 1238 TPHPTTTPHPTTI--THSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHP 1295

Query: 506  TSTEGGAASPTSPTYSTPSTSP 527
            T+T     +P   T   P+T+P
Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTTP 1317



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 54/240 (22%), Positives = 73/240 (30%), Gaps = 34/240 (14%)

Query: 341  GQGRSPGS----------GSQSSGWHEVEPGMPS-----PTTLKKSEKSGFSSPSPSQTS 385
            G  RSPGS          GS    W E  P  P+     P T      +    P P+ TS
Sbjct: 965  GTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTS 1024

Query: 386  SLGTAFTQHHRPVITGPRASPHATPSTLH--FPTSPIIQQPGPYFSH--------PAIRY 435
                  T H          +P  +P T      T+P +    P F+         PA+  
Sbjct: 1025 DSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTP 1084

Query: 436  HPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN-PFLPTPMLPP--------PP 486
             P  T    +            +V  L+P      +    P L T             P 
Sbjct: 1085 EPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPD 1144

Query: 487  PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQ 546
            P P   P   P P   P   +T     +P  PT   P+T+P    ++     P     PQ
Sbjct: 1145 PSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQ 1204



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 43/184 (23%), Positives = 65/184 (35%), Gaps = 25/184 (13%)

Query: 363  PSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 422
            P PTT      +   + +P  T++     T H  P    P ++P  T  T+  PTS   +
Sbjct: 1293 PHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPH--PTTPDPSSTPVIT--TVSLPTSLGTE 1348

Query: 423  QPGPYFSHPAIR--YHPQETLKEFVQLVCPDAGQQAGQVGFL--------NPNGSSQGKV 472
               P  + P ++   HPQ T         P       Q+  L        +P+ SS    
Sbjct: 1349 LSSPTLA-PTVKPSLHPQLTF------TAPAPHTSTSQIPTLEPSPALESSPSRSSTATS 1401

Query: 473  HNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFV 532
             +P       PP    P   P P   P +    T +     SPT+     P   P    +
Sbjct: 1402 MDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDP----L 1457

Query: 533  SVGP 536
            ++GP
Sbjct: 1458 TLGP 1461


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 75/310 (24%), Positives = 101/310 (32%), Gaps = 49/310 (15%)

Query: 277 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 335
           S  P     GP  S+S     S    SP A RR S        +++ L S    + SP  
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 336 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFT 392
             P   G  R+P   SQ    G   + P   +P     +   G  S SP  T S   A  
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314

Query: 393 QHHRPVITG---------------PRA--SPHATPSTLHFPT--------------SPII 421
               P +                 P A  SP A PS    P+              SP +
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374

Query: 422 QQPGPYFSHPAI--------RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH 473
           Q    +   P +        +  P   L        P A      +   +P   +   VH
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434

Query: 474 NPFLPTPMLPPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAASPTSPTYSTPSTSPAN 529
              L  P  PPP PP   P + P   PV P   PP+ +    AA P     S P++ P +
Sbjct: 435 --LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492

Query: 530 RFVSVGPRDP 539
              +  P+ P
Sbjct: 493 PSATPPPQAP 502



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 67/271 (24%), Positives = 96/271 (35%), Gaps = 36/271 (13%)

Query: 295 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 351
           E+    ++S GA R +    P T S +  +R ++   E+  P   P    +  + G    
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208

Query: 352 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHR--PVITG-PRASPH 407
            S   E     PSP   ++ S   G   P+    SS  T  +   R  P   G PRA  H
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268

Query: 408 AT---PSTLHFPTSPIIQQP--------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 456
            +   P  L     P +  P        GP  S P     P   L+       P      
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP------ 322

Query: 457 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPV--PLPVPDTKPPTTSTEGGAAS 514
                  P+ SS        L TP LP  PP P A P    LP P   PP+ +T    + 
Sbjct: 323 -----ATPHSSSL----TCQLATP-LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372

Query: 515 PTSPTYSTPSTSPANRFVSVGPRDPSFVNIP 545
               T+S   + P +   +  P+ P  + +P
Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALP 403



 Score = 36.2 bits (82), Expect = 0.081
 Identities = 62/259 (23%), Positives = 88/259 (33%), Gaps = 47/259 (18%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 362
           SP A   S  +TS  S T  L++    + SP   P  T   ++P + +       + P  
Sbjct: 356 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 406

Query: 363 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 410
             P+       S  ++PSP   ++L        F+    P +         P  SP ATP
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466

Query: 411 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 454
            +          L  P SP    P       P  + P +   P +  K   Q   P A  
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 524

Query: 455 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPPPPPMARPVPLPVPDTKPPTTST 508
                   +P  S  G+   PF P+  LP      PPP  P     PL      PP + T
Sbjct: 525 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582

Query: 509 EGGAASPTSPTYSTPSTSP 527
                 P +P   T  + P
Sbjct: 583 LQAPRRPPTPGPDTSVSGP 601



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 36/195 (18%)

Query: 377 SSPSPSQTSSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQQPG---PYFSHPA 432
           + P P    +L T   Q    P  + P  +P +  ++L  P SP+   P    P  + P 
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPL 570

Query: 433 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMAR 492
           ++  P       +Q     A ++        P       V  P L   + P PPPPP   
Sbjct: 571 LQVPPSPPASPTLQ-----APRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRS 618

Query: 493 P-VPLPVPDTKPPTTST--------------EGGAASPTSPTYSTPSTSPANRFVSVGPR 537
           P   L  PD    ++S               EGGAA+   P     +  PA    S GP 
Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPA 676

Query: 538 DP-SFVNIPQQTQSW 551
            P +F   P     W
Sbjct: 677 PPLAFRGAPGAPLPW 691


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%)

Query: 229 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 288
           H A   + + P  P  A  K + +  +L                +  + + P+ A  G  
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332

Query: 289 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 348
              +    +S  +  P A   + P  S  S+T+               P +   G  P  
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375

Query: 349 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 408
                G H   PG P            F  P PS T   G    QH+      P   P  
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421

Query: 409 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 468
            P  +  P  P+ Q P     HP   + P            P   Q  G      P GS 
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459

Query: 469 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
                QGK   P  P  M+PPPPPPP  +P P P     PP    +     P  P+ S  
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518

Query: 524 STSP 527
           S++P
Sbjct: 519 SSTP 522


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%)

Query: 229 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 288
           H A   + + P  P  A  K + +  +L                +  + + P+ A  G  
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332

Query: 289 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 348
              +    +S  +  P A   + P  S  S+T+               P +   G  P  
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375

Query: 349 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 408
                G H   PG P            F  P PS T   G    QH+      P   P  
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421

Query: 409 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 468
            P  +  P  P+ Q P     HP   + P            P   Q  G      P GS 
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459

Query: 469 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
                QGK   P  P  M+PPPPPPP  +P P P     PP    +     P  P+ S  
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518

Query: 524 STSP 527
           S++P
Sbjct: 519 SSTP 522


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%)

Query: 229 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 288
           H A   + + P  P  A  K + +  +L                +  + + P+ A  G  
Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332

Query: 289 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 348
              +    +S  +  P A   + P  S  S+T+               P +   G  P  
Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375

Query: 349 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 408
                G H   PG P            F  P PS T   G    QH+      P   P  
Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421

Query: 409 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 468
            P  +  P  P+ Q P     HP   + P            P   Q  G      P GS 
Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459

Query: 469 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
                QGK   P  P  M+PPPPPPP  +P P P     PP    +     P  P+ S  
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518

Query: 524 STSP 527
           S++P
Sbjct: 519 SSTP 522



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 6/59 (10%)

Query: 475 PFLPTPMLPPPPPPP------MARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
           P LP    PPPPPPP      M  P P P P   P    T  G      P +  P   P
Sbjct: 575 PPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 73/291 (25%), Positives = 101/291 (34%), Gaps = 56/291 (19%)

Query: 265 SGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPG--AMRRSLPSTSSTSS 319
           +G+ S T L ++  T     T    S +      S +  SM+P   ++ R LP  S T  
Sbjct: 257 TGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGM 316

Query: 320 TKRLKSVE-DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPT-TLKKSEKSGFS 377
             R    + D   S    P      R+P   S +      +P   SPT T  ++  +G  
Sbjct: 317 LSRTSLTKMDSTASISRTPPRASITRTPSRASPTG-----KPSTASPTGTPSRASPTG-- 369

Query: 378 SPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHP 437
             SPS  S  G + T    P  T PRASP  TPST      P    P    S  +I    
Sbjct: 370 --SPSTASLTGLSSTAS--PTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSI---- 421

Query: 438 QETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLP 497
                                        +      +P    P   P   PP A P   P
Sbjct: 422 -----------------------------TKMDSTASPTRTPPRASPTGTPPRASPTGTP 452

Query: 498 VPDTKPPTTSTEGGAASPT-SPTYSTPSTSPANRFVSVGPRDPSFVNIPQQ 547
              +   T ST    ASPT SP+ ++P+ SP+    +  P   S    P +
Sbjct: 453 SRASPTGTQST----ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSR 499



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 74/319 (23%), Positives = 104/319 (32%), Gaps = 28/319 (8%)

Query: 234 SQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSD 293
           S++     PS A +   P    L        +G  S   L+         GT P  SL  
Sbjct: 9   SRASPTRTPSTASLTGTPSRASL--------TGTPSTASLMGTPSRASLTGTPPRASLKG 60

Query: 294 LESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSS 353
             S +   +SP   R SL    S+S   R  S+      P          R+      S+
Sbjct: 61  TTSMASLMVSPS--RASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPST 118

Query: 354 GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG--PRASPHATPS 411
                 P   S TT         S  S S T S   A T   R  +T   PRAS   TPS
Sbjct: 119 ASLTRSPSRASLTTTP-------SRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPS 171

Query: 412 TLHFPTSPIIQQPG--PYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQ 469
           T     +P    P   P  + P          K            +A   G   P  S  
Sbjct: 172 TASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTG-TPPRASPT 230

Query: 470 GKVHNPFLPTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 525
           G    P     M+P        PP A P  +    +     ST     +P+ P+ ++P+ 
Sbjct: 231 GS--PPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTG 288

Query: 526 SPANRFVSVGPRDPSFVNI 544
           +P+   +S+ P   S + +
Sbjct: 289 TPSRASLSMTPSTASLMRM 307



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 60/247 (24%), Positives = 84/247 (34%), Gaps = 48/247 (19%)

Query: 282 AAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGE-EPFYT 340
           A+ TG   + S   S S  S +    R SL  T S +S  +++S      +P    P +T
Sbjct: 464 ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWT 523

Query: 341 GQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT 400
               SP +GS S+    +  G PS   L ++      + +PS+ S            + T
Sbjct: 524 PSTASP-TGSPSTA---LAMGSPSRAALTRTPSRASLTRTPSRAS------------LTT 567

Query: 401 GPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 460
             RAS   TPST+     P    P    S  +    P   L                   
Sbjct: 568 PSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSAL------------------- 608

Query: 461 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTY 520
            L    S+      P    P   P   PP A P       T  P  ++  G     SPT 
Sbjct: 609 -LTKMDSTASITRTP----PRASPTETPPRASP-------TGTPPRASPTGTPPRASPTG 656

Query: 521 STPSTSP 527
           + P  SP
Sbjct: 657 TPPRASP 663



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 49/198 (24%), Positives = 68/198 (34%), Gaps = 26/198 (13%)

Query: 233 SSQSESPS-QPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAG-TGPNFS 290
           S  + SP+  PS A +   P    L   +S  T+ +         + TP  A  TG    
Sbjct: 478 SPSTASPTGSPSRASLTRTPSRASLTKMES--TASITRTPSRASPTWTPSTASPTG---- 531

Query: 291 LSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGS 350
            S   + +  S S  A+ R+    S T +  R         S    P      R P S S
Sbjct: 532 -SPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSAS 590

Query: 351 QSSGWHEVEP-GMPSPTTLKKSEKSGFSSPSPSQTS----------------SLGTAFTQ 393
            +       P GMPS   L K + +   + +P + S                +  T    
Sbjct: 591 PTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPP 650

Query: 394 HHRPVITGPRASPHATPS 411
              P  T PRASP  TPS
Sbjct: 651 RASPTGTPPRASPTGTPS 668


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 54/220 (24%), Positives = 80/220 (36%), Gaps = 20/220 (9%)

Query: 302 MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 361
           + P A  + L +  + +STK +  V  +   P   P      + P   +         P 
Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832

Query: 362 MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPII 421
           +P P      ++S  + P PS  S + +   Q     I      P   P+    P  P+ 
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-----IASQFPPPPTPPAMESQPLKPVP 887

Query: 422 QQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPM 481
               P  S PA++  P+      + +  PD            P       V  P  P+P+
Sbjct: 888 ANVAPQ-SPPAVKAKPKWQPSS-IPVPSPD----------FPPPPPESSLVFPPPPPSPV 935

Query: 482 -LPPPPPPPMARPVP--LPVPDTKPPTTSTEGGAASPTSP 518
             PPPPPPP A P P     P  K   TS+ GG   P +P
Sbjct: 936 PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 462 LNPNGSSQGKVHNPFLPT----PMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTS 517
           L P  S Q K+  P+  +    P+ PPPPPPP   P P P P   P  ++   G+A+P  
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664

Query: 518 PTYST 522
             YST
Sbjct: 665 VKYST 669



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 53/209 (25%), Positives = 70/209 (33%), Gaps = 45/209 (21%)

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGP---------------RA 404
           P +P+P   +   K   + P+P+ T ++    TQ   P  T P                 
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826

Query: 405 SPHATPSTLHFPTSPIIQQ------PGPYFSHPAI------RYHPQET--------LKEF 444
           SP   P  +  PT P  Q       P P    P++      ++ P  T        LK  
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV 886

Query: 445 VQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP------MLPPPPPPPMARPVPLPV 498
              V P +           P   S   V +P  P P      + PPPPP P+  P P P 
Sbjct: 887 PANVAPQSPPAVKAKPKWQP---SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP-PP 942

Query: 499 PDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
           P T  PT    G     TS T S     P
Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKP 971



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 12/70 (17%)

Query: 471 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPP----------TTSTEGGAASPTSPTY 520
           K+H     T + PP PPPP   P+P P+P   PP          +T T     +  +P  
Sbjct: 748 KIHQVQHITQVAPPTPPPP--PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805

Query: 521 STPSTSPANR 530
            TP   PA +
Sbjct: 806 PTPPVPPAKK 815



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 53/240 (22%), Positives = 81/240 (33%), Gaps = 24/240 (10%)

Query: 290 SLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSG 349
           S  D  S S  S+  G+   S+P + S  S +    V D       +P    + +S  S 
Sbjct: 522 SAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDT------QPAGHVRSQSIVSS 575

Query: 350 SQSSGWHEVEPGMPSPTTLKKSEKSGFSS--PSPSQTSSLGTAFTQHH-RPVITGPRASP 406
             S  W        S     +S    ++S  P  S    + T +T     P +  P   P
Sbjct: 576 VFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP 635

Query: 407 HATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNG 466
              P     P  P+  Q  P     A  +    T+         +A Q +G +       
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL-----QNASQHSGALFKPPTPP 690

Query: 467 SSQGKVHNPFL---PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 523
             Q +   P +   P  ++PPPPPPP       P P         +    +P+ P +S P
Sbjct: 691 VMQSQSVKPQILVPPNGVVPPPPPPP-------PPPTPGSAMAQLKPAPCAPSLPQFSAP 743



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 50/188 (26%), Positives = 65/188 (34%), Gaps = 26/188 (13%)

Query: 360  PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTS- 418
            P  P PT     +KSG      S+TSS G       +P  T  R S   + S    P   
Sbjct: 939  PPPPPPTASPTPDKSGSPGKKTSKTSSPGGK-----KPPPTPQRNSSIKSSSGAEHPEPK 993

Query: 419  -PIIQQPGPYFSHPAIRYHP-QETLKEFVQLVCPDAGQ------------QAGQVGFLNP 464
             P +      F+ PA    P +ETL        P  G+            Q G V    P
Sbjct: 994  RPSVDSLVSKFTPPAESGSPSKETLPP--PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051

Query: 465  NGSSQGKVHNPFLPTPM----LPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTY 520
              S +GK      P+P      PPPPP       P+ +P      TS +    +P    +
Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW 1111

Query: 521  STPSTSPA 528
            S  S   A
Sbjct: 1112 SKMSVKKA 1119



 Score = 29.3 bits (64), Expect = 9.9
 Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 3/75 (4%)

Query: 475 PFLPTPMLPPPPPPPM-ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 533
           P +P P+ P  PP P+   P P       P  T       +P  P        PA+    
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826

Query: 534 VGPRDPSFVNIPQQT 548
             P  P  V +P  T
Sbjct: 827 SPPTPP--VPVPPPT 839


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 42/131 (32%), Positives = 55/131 (41%), Gaps = 9/131 (6%)

Query: 402  PRASPHATPSTLHFPTSPI-IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 460
            P+ +PH     LH PTSP+ +  P P    PA +  P+  +      + P AG   G   
Sbjct: 1351 PQFAPHGR-HPLHQPTSPLPLYSPAPQHP-PAHKQGPKHFIFSHHPQMMPAAGAAGGPGS 1408

Query: 461  FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTK----PPTTSTEGGAASPT 516
               P G S    H+P  P     P PP P   P+P P P T     PPT+      AS  
Sbjct: 1409 --RPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGP 1466

Query: 517  SPTYSTPSTSP 527
              T + PS +P
Sbjct: 1467 PGTANPPSANP 1477



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 4/84 (4%)

Query: 453  GQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGA 512
            G   G +G L    S    +H  +   P   PPP  P  +P  LP P  +PP     G  
Sbjct: 1248 GHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQP-SLPPPPQQPPPLPQLGSI 1306

Query: 513  ASPTSPTYSTPSTSPANRFVSVGP 536
              P +   S P   P   F + GP
Sbjct: 1307 PPPPA---SAPPVGPHRHFHAHGP 1327



 Score = 29.3 bits (64), Expect = 9.9
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 451  DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP 489
            DAG++  +    + + + +G V +   P   +PPPPPPP
Sbjct: 1149 DAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPP 1187


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 359
           +P  +  + P   + ++ + L     E  +P   EEP   T +  +P +  + +      
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 550

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 417
           P  P+PTT K+   +     +P  T+  GTA T    P  T P+  A     P+T   PT
Sbjct: 551 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
           S    +P P          P+E      +   P             P G++   +  P  
Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 657

Query: 478 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 535
            TP  P P    P     P      KP PTT  E    +P  P  +TP   PA       
Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 716

Query: 536 PRDPSFVNIPQQTQ 549
           P   S V+ P  T+
Sbjct: 717 PPTTSEVSTPTTTK 730



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)

Query: 363 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 417
           P+PTT K +     E S  ++  P+ T+    A T   +P  T P+     TP     P 
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 459

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 475
               ++P P          P+ET     + + P   ++        P  ++  ++    P
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 527
             PTP  P  P P   +      P    PTT  E    +P  P  +TP  T+P
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 417
           P  P+PTT K+   +    P+P+ T S  T  T+   P  T   P      +P+T   P 
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 427

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
               ++P P          P+E      +   P   ++        P  ++  K   P  
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 486

Query: 478 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 533
           P  + P  P    P    +P P   P+   PTT  E    +P  P  +TP  +  N    
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545

Query: 534 VGPRDP 539
             P  P
Sbjct: 546 PAPTTP 551



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 362
           +P   +   P+T    +    K  E    +P E    T +G +P +  + +     +P  
Sbjct: 539 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596

Query: 363 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 415
              +PTT K+   +    P+P  T+  GTA T    P  T P+     +P  T P+TL  
Sbjct: 597 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654

Query: 416 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 475
           P     ++P P    P     P  T  +                    P    +     P
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 697

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 526
             P P  P  P P          P+T PPTT   ST      PT    SP  STP  S  
Sbjct: 698 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749

Query: 527 PANRFVSVGPRDP 539
           P  + +   P++P
Sbjct: 750 PTPKALENSPKEP 762



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)

Query: 309 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 368
           +S P+T+   +    KS      +P E    T +  +P +  + +      P  P+PTT 
Sbjct: 394 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 447

Query: 369 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 422
           K+   +    P+P+ T     A T    P  T P+ +   TP  L  PT+P        +
Sbjct: 448 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 504

Query: 423 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 482
           +P P          P+E      +   P   + A       PN   +     P  P P  
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 558

Query: 483 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 518
           P  P P   +      P    PTT  E    +P  P
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)

Query: 294 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 351
           +E +S   ++P +   + P+  + ++TK   L + ++   +  +EP  T       +  +
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 238

Query: 352 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 411
           S+      P  P+PTT K +  +    P+P+ T        +   P  T   A P  T S
Sbjct: 239 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 293

Query: 412 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 471
               PT+P  ++P P          P+E      +   P   ++           + +  
Sbjct: 294 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 341

Query: 472 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
              P  P P  P  P P   +      P    PTT+ E    +P  P  +T  ++P
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)

Query: 360 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 414
           P  P+PTT K+      E +  +   P+ T+    A T    P  T P+  P  T +   
Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 380

Query: 415 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 474
            PT+P    P    S P     P  T  +       +           +P  + +     
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 430

Query: 475 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 534
           P  P P  P  P P   +      P    PTT+ +    +P  P  +TP  +       +
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490

Query: 535 GPRDP 539
            P  P
Sbjct: 491 TPTTP 495


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 359
           +P  +  + P   + ++ + L     E  +P   EEP   T +  +P +  + +      
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 591

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 417
           P  P+PTT K+   +     +P  T+  GTA T    P  T P+  A     P+T   PT
Sbjct: 592 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
           S    +P P          P+E      +   P             P G++   +  P  
Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 698

Query: 478 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 535
            TP  P P    P     P      KP PTT  E    +P  P  +TP   PA       
Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 757

Query: 536 PRDPSFVNIPQQTQ 549
           P   S V+ P  T+
Sbjct: 758 PPTTSEVSTPTTTK 771



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)

Query: 363 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 417
           P+PTT K +     E S  ++  P+ T+    A T   +P  T P+     TP     P 
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 500

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 475
               ++P P          P+ET     + + P   ++        P  ++  ++    P
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 527
             PTP  P  P P   +      P    PTT  E    +P  P  +TP  T+P
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 417
           P  P+PTT K+   +    P+P+ T S  T  T+   P  T   P      +P+T   P 
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 468

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
               ++P P          P+E      +   P   ++        P  ++  K   P  
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 527

Query: 478 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 533
           P  + P  P    P    +P P   P+   PTT  E    +P  P  +TP  +  N    
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586

Query: 534 VGPRDP 539
             P  P
Sbjct: 587 PAPTTP 592



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 362
           +P   +   P+T    +    K  E    +P E    T +G +P +  + +     +P  
Sbjct: 580 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637

Query: 363 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 415
              +PTT K+   +    P+P  T+  GTA T    P  T P+     +P  T P+TL  
Sbjct: 638 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695

Query: 416 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 475
           P     ++P P    P     P  T  +                    P    +     P
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 738

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 526
             P P  P  P P          P+T PPTT   ST      PT    SP  STP  S  
Sbjct: 739 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790

Query: 527 PANRFVSVGPRDP 539
           P  + +   P++P
Sbjct: 791 PTPKALENSPKEP 803



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)

Query: 309 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 368
           +S P+T+   +    KS      +P E    T +  +P +  + +      P  P+PTT 
Sbjct: 435 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 488

Query: 369 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 422
           K+   +    P+P+ T     A T    P  T P+ +   TP  L  PT+P        +
Sbjct: 489 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 545

Query: 423 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 482
           +P P          P+E      +   P   + A       PN   +     P  P P  
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 599

Query: 483 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 518
           P  P P   +      P    PTT  E    +P  P
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)

Query: 294 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 351
           +E +S   ++P +   + P+  + ++TK   L + ++   +  +EP  T       +  +
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 279

Query: 352 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 411
           S+      P  P+PTT K +  +    P+P+ T        +   P  T   A P  T S
Sbjct: 280 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 334

Query: 412 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 471
               PT+P  ++P P          P+E      +   P   ++           + +  
Sbjct: 335 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 382

Query: 472 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
              P  P P  P  P P   +      P    PTT+ E    +P  P  +T  ++P
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)

Query: 360 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 414
           P  P+PTT K+      E +  +   P+ T+    A T    P  T P+  P  T +   
Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 421

Query: 415 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 474
            PT+P    P    S P     P  T  +       +           +P  + +     
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 471

Query: 475 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 534
           P  P P  P  P P   +      P    PTT+ +    +P  P  +TP  +       +
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531

Query: 535 GPRDP 539
            P  P
Sbjct: 532 TPTTP 536


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 359
           +P  +  + P   + ++ + L     E  +P   EEP   T +  +P +  + +      
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 643

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 417
           P  P+PTT K+   +     +P  T+  GTA T    P  T P+  A     P+T   PT
Sbjct: 644 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
           S    +P P          P+E      +   P             P G++   +  P  
Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 750

Query: 478 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 535
            TP  P P    P     P      KP PTT  E    +P  P  +TP   PA       
Sbjct: 751 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 809

Query: 536 PRDPSFVNIPQQTQ 549
           P   S V+ P  T+
Sbjct: 810 PPTTSEVSTPTTTK 823



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)

Query: 363 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 417
           P+PTT K +     E S  ++  P+ T+    A T   +P  T P+     TP     P 
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 552

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 475
               ++P P          P+ET     + + P   ++        P  ++  ++    P
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 527
             PTP  P  P P   +      P    PTT  E    +P  P  +TP  T+P
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 417
           P  P+PTT K+   +    P+P+ T S  T  T+   P  T   P      +P+T   P 
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 520

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
               ++P P          P+E      +   P   ++        P  ++  K   P  
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 579

Query: 478 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 533
           P  + P  P    P    +P P   P+   PTT  E    +P  P  +TP  +  N    
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638

Query: 534 VGPRDP 539
             P  P
Sbjct: 639 PAPTTP 644



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 362
           +P   +   P+T    +    K  E    +P E    T +G +P +  + +     +P  
Sbjct: 632 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689

Query: 363 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 415
              +PTT K+   +    P+P  T+  GTA T    P  T P+     +P  T P+TL  
Sbjct: 690 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747

Query: 416 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 475
           P     ++P P    P     P  T  +                    P    +     P
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 790

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 526
             P P  P  P P          P+T PPTT   ST      PT    SP  STP  S  
Sbjct: 791 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842

Query: 527 PANRFVSVGPRDP 539
           P  + +   P++P
Sbjct: 843 PTPKALENSPKEP 855



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)

Query: 309 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 368
           +S P+T+   +    KS      +P E    T +  +P +  + +      P  P+PTT 
Sbjct: 487 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 540

Query: 369 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 422
           K+   +    P+P+ T     A T    P  T P+ +   TP  L  PT+P        +
Sbjct: 541 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 597

Query: 423 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 482
           +P P          P+E      +   P   + A       PN   +     P  P P  
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 651

Query: 483 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 518
           P  P P   +      P    PTT  E    +P  P
Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)

Query: 294 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 351
           +E +S   ++P +   + P+  + ++TK   L + ++   +  +EP  T       +  +
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331

Query: 352 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 411
           S+      P  P+PTT K +  +    P+P+ T        +   P  T   A P  T S
Sbjct: 332 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 386

Query: 412 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 471
               PT+P  ++P P          P+E      +   P   ++           + +  
Sbjct: 387 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 434

Query: 472 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
              P  P P  P  P P   +      P    PTT+ E    +P  P  +T  ++P
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)

Query: 360 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 414
           P  P+PTT K+      E +  +   P+ T+    A T    P  T P+  P  T +   
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 473

Query: 415 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 474
            PT+P    P    S P     P  T  +       +           +P  + +     
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 523

Query: 475 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 534
           P  P P  P  P P   +      P    PTT+ +    +P  P  +TP  +       +
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583

Query: 535 GPRDP 539
            P  P
Sbjct: 584 TPTTP 588


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 359
           +P  +  + P   + ++ + L     E  +P   EEP   T +  +P +  + +      
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 684

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 417
           P  P+PTT K+   +     +P  T+  GTA T    P  T P+  A     P+T   PT
Sbjct: 685 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
           S    +P P          P+E      +   P             P G++   +  P  
Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 791

Query: 478 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 535
            TP  P P    P     P      KP PTT  E    +P  P  +TP   PA       
Sbjct: 792 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 850

Query: 536 PRDPSFVNIPQQTQ 549
           P   S V+ P  T+
Sbjct: 851 PPTTSEVSTPTTTK 864



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)

Query: 363 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 417
           P+PTT K +     E S  ++  P+ T+    A T   +P  T P+     TP     P 
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 593

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 475
               ++P P          P+ET     + + P   ++        P  ++  ++    P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 527
             PTP  P  P P   +      P    PTT  E    +P  P  +TP  T+P
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%)

Query: 360 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 417
           P  P+PTT K+   +    P+P+ T S  T  T+   P  T   P      +P+T   P 
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 561

Query: 418 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 477
               ++P P          P+E      +   P   ++        P  ++  K   P  
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 620

Query: 478 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 533
           P  + P  P    P    +P P   P+   PTT  E    +P  P  +TP  +  N    
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679

Query: 534 VGPRDP 539
             P  P
Sbjct: 680 PAPTTP 685



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%)

Query: 303 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 362
           +P   +   P+T    +    K  E    +P E    T +G +P +  + +     +P  
Sbjct: 673 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730

Query: 363 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 415
              +PTT K+   +    P+P  T+  GTA T    P  T P+     +P  T P+TL  
Sbjct: 731 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788

Query: 416 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 475
           P     ++P P    P     P  T  +                    P    +     P
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 831

Query: 476 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 526
             P P  P  P P          P+T PPTT   ST      PT    SP  STP  S  
Sbjct: 832 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883

Query: 527 PANRFVSVGPRDP 539
           P  + +   P++P
Sbjct: 884 PTPKALENSPKEP 896



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%)

Query: 309 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 368
           +S P+T+   +    KS      +P E    T +  +P +  + +      P  P+PTT 
Sbjct: 528 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 581

Query: 369 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 422
           K+   +    P+P+ T     A T    P  T P+ +   TP  L  PT+P        +
Sbjct: 582 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 638

Query: 423 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 482
           +P P          P+E      +   P   + A       PN   +     P  P P  
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 692

Query: 483 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 518
           P  P P   +      P    PTT  E    +P  P
Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%)

Query: 294 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 351
           +E +S   ++P +   + P+  + ++TK   L + ++   +  +EP  T       +  +
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372

Query: 352 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 411
           S+      P  P+PTT K +  +    P+P+ T        +   P  T   A P  T S
Sbjct: 373 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 427

Query: 412 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 471
               PT+P  ++P P          P+E      +   P   ++           + +  
Sbjct: 428 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 475

Query: 472 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 527
              P  P P  P  P P   +      P    PTT+ E    +P  P  +T  ++P
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%)

Query: 360 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 414
           P  P+PTT K+      E +  +   P+ T+    A T    P  T P+  P  T +   
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 514

Query: 415 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 474
            PT+P    P    S P     P  T  +       +           +P  + +     
Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 564

Query: 475 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 534
           P  P P  P  P P   +      P    PTT+ +    +P  P  +TP  +       +
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624

Query: 535 GPRDP 539
            P  P
Sbjct: 625 TPTTP 629


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 19/169 (11%)

Query: 345 SPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRA 404
           SP     S G H   P +P P   + S      SP PS+T       T HH P   G + 
Sbjct: 805 SPIMPPGSQGSHIHCPQLPQPALHQNSP-----SPVPSRTP------TPHHTPPSIGAQQ 853

Query: 405 SPHATPSTLHFPTSPIIQQPGPYFS--HPAIRYHPQETLKEFVQLVCPD--AGQQAGQVG 460
            P AT      PT P +  PGP     HP  R  P     +  Q V P   A   A Q  
Sbjct: 854 PP-ATTIPAPVPTPPAMP-PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911

Query: 461 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP-VPLPVPDTKPPTTST 508
              P          P    P+LPP P  P+++P V +    + PP+TS+
Sbjct: 912 -QQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 50/222 (22%), Positives = 81/222 (36%), Gaps = 24/222 (10%)

Query: 336 EPFYTGQGRSPG-SGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPS--PSQTSSLGTAFT 392
           +P  T  G  P  S  + S  +++ P +   + L +  +   + P   P QT  L     
Sbjct: 679 QPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPL----- 733

Query: 393 QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDA 452
           QHH     G  A P A    + +   P +QQP            P + +      + P +
Sbjct: 734 QHH-----GQLAQPGALNPPMGY--GPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSS 786

Query: 453 GQQAGQVGFLNPNGSSQGKVHNPFLPTPM------LPPPPPPPMARPVPLPVPDTKPPTT 506
           GQ       ++   SS   V++P +P          P  P P + +  P PVP   P   
Sbjct: 787 GQAPVSQAQMS---SSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPH 843

Query: 507 STEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQT 548
            T     +   P  + P+  P    +  GP+  +    P+QT
Sbjct: 844 HTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQT 885



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 54/258 (20%), Positives = 85/258 (32%), Gaps = 13/258 (5%)

Query: 280 PIAAGTGPNFSLSDLESSSYYSM-SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPF 338
           P++   GPN        +S   +  P  +R S+P+      T +    +    S  + P 
Sbjct: 666 PVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPI 725

Query: 339 YTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 398
              Q        Q +    + P M     +++    G   P  +Q  S G   T      
Sbjct: 726 VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQ-TQFPSQGMNVTNIPLAP 784

Query: 399 ITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEF----VQLVCPDAGQ 454
            +G      A  S+   P +  I  PG   SH      PQ  L +     V    P    
Sbjct: 785 SSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHH 844

Query: 455 QAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS--TEGGA 512
               +G   P  ++   +  P    P +PP P      P P   P   PPTT    +   
Sbjct: 845 TPPSIGAQQPPATT---IPAPVPTPPAMPPGPQSQALHPPPRQTP--TPPTTQLPQQVQP 899

Query: 513 ASPTSPTYSTPSTSPANR 530
           + P +P+   P   P ++
Sbjct: 900 SLPAAPSADQPQQQPRSQ 917



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 27/100 (27%), Positives = 32/100 (32%), Gaps = 6/100 (6%)

Query: 454  QQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAA 513
            Q+ G VG     G        P  PT   P  P  P     P P P    P       AA
Sbjct: 1836 QRTGVVG--QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAA 1893

Query: 514  SPTSPTYS----TPSTSPANRFVSVGPRDPSFVNIPQQTQ 549
             P S   +    TP T P      +    P+ V +  Q Q
Sbjct: 1894 GPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQ 1933



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 46/205 (22%), Positives = 68/205 (33%), Gaps = 23/205 (11%)

Query: 351  QSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 410
            Q +G    + G+PSPT    +  +G   P+  QT                 P + P  TP
Sbjct: 1836 QRTGVVGQQQGLPSPTPATPTTPTG-QQPTTPQTPQ---------------PTSQPQPTP 1879

Query: 411  STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 470
                 P  P  Q  GP     A       T  +  Q   P     A ++       +   
Sbjct: 1880 PNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ 1939

Query: 471  K--VHNPFLPTPML-PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTS- 526
            +   H      P+    PP  PMA     P P T+ P+   E G   PT      P +  
Sbjct: 1940 RQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPG-MGPTGMQQQPPWSQG 1998

Query: 527  --PANRFVSVGPRDPSFVNIPQQTQ 549
              P  + +  G   P+ +++ Q  Q
Sbjct: 1999 GLPQPQQLQSGMPRPAMMSVAQHGQ 2023



 Score = 29.3 bits (64), Expect = 9.9
 Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 9/110 (8%)

Query: 29   CPSPPPRRTRIPQRPAV-MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFK 87
            CP P  RR  I    +V  + P CL    +H  +   L +V+   YT  ++ A       
Sbjct: 1385 CPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGD 1444

Query: 88   KHEKRMSKEEERAVKDELLSEKPEVKQKWASRLLAK-LRKDIRPEYREDF 136
             +       +++         KP+  Q+W  ++L K + + I  +Y++ F
Sbjct: 1445 DYIFHCHPPDQKI-------PKPKRLQEWYKKMLDKAVSERIVHDYKDIF 1487


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,508,410
Number of Sequences: 37866
Number of extensions: 1782914
Number of successful extensions: 26675
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 524
Number of HSP's successfully gapped in prelim test: 864
Number of HSP's that attempted gapping in prelim test: 12171
Number of HSP's gapped (non-prelim): 7769
length of query: 554
length of database: 18,247,518
effective HSP length: 107
effective length of query: 447
effective length of database: 14,195,856
effective search space: 6345547632
effective search space used: 6345547632
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.