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Search of human proteins with 223633988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
(1806 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223633988 hypothetical protein LOC85379 [Homo sapiens] 3657 0.0
gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo ... 3060 0.0
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens] 81 8e-15
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 58 1e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 57 2e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 56 3e-07
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 56 3e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 4e-07
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 55 5e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 7e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 7e-06
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 51 9e-06
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 51 9e-06
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 51 9e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 49 3e-05
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 49 6e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 48 8e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 48 8e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 48 8e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 48 8e-05
gi|239744140 PREDICTED: hypothetical protein [Homo sapiens] 48 8e-05
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 48 8e-05
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 47 1e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 47 1e-04
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 47 1e-04
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 47 1e-04
gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo sa... 47 2e-04
gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo sa... 47 2e-04
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-04
gi|169167681 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-04
>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
Length = 1806
Score = 3657 bits (9482), Expect = 0.0
Identities = 1806/1806 (100%), Positives = 1806/1806 (100%)
Query: 1 MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARL 60
MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARL
Sbjct: 1 MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARL 60
Query: 61 LPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
LPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGS
Sbjct: 61 LPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA
Sbjct: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
Query: 181 KPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKR 240
KPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKR
Sbjct: 181 KPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKR 240
Query: 241 RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRK 300
RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRK
Sbjct: 241 RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRK 300
Query: 301 VADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLS 360
VADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLS
Sbjct: 301 VADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLS 360
Query: 361 KPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRV 420
KPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRV
Sbjct: 361 KPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRV 420
Query: 421 ADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQ 480
ADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQ
Sbjct: 421 ADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQ 480
Query: 481 ERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEP 540
ERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEP
Sbjct: 481 ERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEP 540
Query: 541 REKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVT 600
REKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVT
Sbjct: 541 REKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVT 600
Query: 601 PEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGR 660
PEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGR
Sbjct: 601 PEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGR 660
Query: 661 DPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHL 720
DPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHL
Sbjct: 661 DPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHL 720
Query: 721 ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA 780
ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA
Sbjct: 721 ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA 780
Query: 781 DLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEE 840
DLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEE
Sbjct: 781 DLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEE 840
Query: 841 HCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQAR 900
HCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQAR
Sbjct: 841 HCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQAR 900
Query: 901 THPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDT 960
THPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDT
Sbjct: 901 THPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDT 960
Query: 961 FSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSP 1020
FSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSP
Sbjct: 961 FSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSP 1020
Query: 1021 VEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL 1080
VEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL
Sbjct: 1021 VEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL 1080
Query: 1081 EMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGP 1140
EMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGP
Sbjct: 1081 EMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGP 1140
Query: 1141 RPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLD 1200
RPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLD
Sbjct: 1141 RPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLD 1200
Query: 1201 IDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLW 1260
IDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLW
Sbjct: 1201 IDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLW 1260
Query: 1261 KPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRK 1320
KPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRK
Sbjct: 1261 KPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRK 1320
Query: 1321 KTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKST 1380
KTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKST
Sbjct: 1321 KTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKST 1380
Query: 1381 GRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRP 1440
GRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRP
Sbjct: 1381 GRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRP 1440
Query: 1441 SLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSF 1500
SLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSF
Sbjct: 1441 SLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSF 1500
Query: 1501 CKDRRSGPFVDQLKQCFSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSA 1560
CKDRRSGPFVDQLKQCFSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSA
Sbjct: 1501 CKDRRSGPFVDQLKQCFSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSA 1560
Query: 1561 TSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDA 1620
TSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDA
Sbjct: 1561 TSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDA 1620
Query: 1621 CPEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDE 1680
CPEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDE
Sbjct: 1621 CPEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDE 1680
Query: 1681 TDNTWMFKDSTEEKSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRP 1740
TDNTWMFKDSTEEKSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRP
Sbjct: 1681 TDNTWMFKDSTEEKSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRP 1740
Query: 1741 EVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKELKSKKRQS 1800
EVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKELKSKKRQS
Sbjct: 1741 EVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKELKSKKRQS 1800
Query: 1801 LYENQV 1806
LYENQV
Sbjct: 1801 LYENQV 1806
>gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo
sapiens]
Length = 1595
Score = 3060 bits (7932), Expect = 0.0
Identities = 1510/1510 (100%), Positives = 1510/1510 (100%)
Query: 1 MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARL 60
MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARL
Sbjct: 1 MATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARL 60
Query: 61 LPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
LPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGS
Sbjct: 61 LPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA
Sbjct: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
Query: 181 KPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKR 240
KPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKR
Sbjct: 181 KPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKR 240
Query: 241 RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRK 300
RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRK
Sbjct: 241 RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRK 300
Query: 301 VADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLS 360
VADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLS
Sbjct: 301 VADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLS 360
Query: 361 KPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRV 420
KPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRV
Sbjct: 361 KPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRV 420
Query: 421 ADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQ 480
ADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQ
Sbjct: 421 ADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQ 480
Query: 481 ERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEP 540
ERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEP
Sbjct: 481 ERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEP 540
Query: 541 REKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVT 600
REKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVT
Sbjct: 541 REKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDPDSCRGGSSVEAPCPSDVT 600
Query: 601 PEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGR 660
PEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGR
Sbjct: 601 PEDDRSFQTVWATVFEHHVERHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWLGR 660
Query: 661 DPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHL 720
DPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHL
Sbjct: 661 DPPDMTKLKKENSRGFDNPETEKLGPTTLLNGELRPYHTPLRDKYPLSENHNNNTFLKHL 720
Query: 721 ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA 780
ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA
Sbjct: 721 ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA 780
Query: 781 DLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEE 840
DLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEE
Sbjct: 781 DLECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEE 840
Query: 841 HCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQAR 900
HCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQAR
Sbjct: 841 HCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQAR 900
Query: 901 THPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDT 960
THPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDT
Sbjct: 901 THPDAFAVQKGPFIVAAREGDPGPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDT 960
Query: 961 FSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSP 1020
FSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSP
Sbjct: 961 FSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQGSP 1020
Query: 1021 VEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL 1080
VEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL
Sbjct: 1021 VEPKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL 1080
Query: 1081 EMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGP 1140
EMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGP
Sbjct: 1081 EMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRGSEDGP 1140
Query: 1141 RPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLD 1200
RPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLD
Sbjct: 1141 RPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYRSSVLD 1200
Query: 1201 IDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLW 1260
IDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLW
Sbjct: 1201 IDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPDTGGLW 1260
Query: 1261 KPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRK 1320
KPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRK
Sbjct: 1261 KPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPPSAPSERYPGGSPIPADPRK 1320
Query: 1321 KTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKST 1380
KTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKST
Sbjct: 1321 KTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVRVSPKSPPTDQKKGTPRKST 1380
Query: 1381 GRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRP 1440
GRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRP
Sbjct: 1381 GRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREGLSIMHEARERRREQPKGRP 1440
Query: 1441 SLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSF 1500
SLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSF
Sbjct: 1441 SLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSF 1500
Query: 1501 CKDRRSGPFV 1510
CKDRRSGPFV
Sbjct: 1501 CKDRRSGPFV 1510
>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
Length = 1729
Score = 81.3 bits (199), Expect = 8e-15
Identities = 75/247 (30%), Positives = 109/247 (44%), Gaps = 30/247 (12%)
Query: 1564 RKQPPSSRLS--SLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDAC 1621
R PPS R +SQTE D S++ S T PP
Sbjct: 1501 RDSPPSWRPQPDGEASQTE--------DVDGTWGSSAARWSDQGPAQTSRRPSQGPPARS 1552
Query: 1622 PEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDET 1681
P + DFSFI+ T +LDS+ ++R L ++ RAP+ SE+
Sbjct: 1553 PSQ---DFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAAD-------- 1601
Query: 1682 DNTWMFKDSTEEKSPRKEESDE---EETASKAERTPV-SHPQRMPAFPGMDPAVLKAQLH 1737
+ +F+DSTE ++ R SDE EE S+ R + + ++ FPG+ P+ LKA+L
Sbjct: 1602 SDAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLR 1661
Query: 1738 KRPEVDSPGE-TPSWAPQPKS----PKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKE 1792
R GE S + Q +S KS PG+ LP +K S+ SP WL+
Sbjct: 1662 PRNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQA 1721
Query: 1793 LKSKKRQ 1799
LK KK++
Sbjct: 1722 LKLKKKK 1728
Score = 36.6 bits (83), Expect = 0.23
Identities = 103/433 (23%), Positives = 158/433 (36%), Gaps = 60/433 (13%)
Query: 35 QAGEASGAPPARILEAKSPLRS----PARLLPLPRL-------APKPFSKEQDVKSPVPS 83
Q EAS A P + +P + +R P P L AP+P S +V P
Sbjct: 321 QTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSL 380
Query: 84 LRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPL----FNKAVFLRP 139
+P +T P P L E DL P G+E G+ + L F++ V P
Sbjct: 381 DQPPATSPRP---LIEVGELLDLTRTFPS-GGEEEAKGDAHLRPTSLVQRRFSEGVLQSP 436
Query: 140 SSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLP-RSAP 198
S + K G +L A+ +G + ++L + RP A +Q T P R +
Sbjct: 437 SQ------DQEKLGGSLA-ALPQG-QGSQLAL--DRPFGAESNWSLSQSFEWTFPTRPSG 486
Query: 199 LS---QDTKPPVPQEEAGQDHPPSKASSVEDTARPL-VEPRPRLKRRPVSAIFTESIQPQ 254
L D+ PP P EA + ++A ++ ++R V + + S + +Q
Sbjct: 487 LGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
Query: 255 KP-------GPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEAL------LRKV 301
P G G + P P T P R+E++E L L
Sbjct: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
Query: 302 ADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSK 361
E + P + G E+P A D+ C++ A+AP L E A + R E ++
Sbjct: 607 TREAALPILEPVLGQEQPAAP---DQPCVLFADAPEPGQALPVEEEAVTL-ARAETTQAR 662
Query: 362 PEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRVA 421
E + L S S W + P P R G G EL + +S
Sbjct: 663 TE---AQDLCRASPEPPGPESSSRWLDDLLASPPP----SGGGARRGAGAELKDTQSPST 715
Query: 422 DGEAAAGGEWASR 434
E G W+ +
Sbjct: 716 CSEGLLG--WSQK 726
Score = 31.6 bits (70), Expect = 7.3
Identities = 88/411 (21%), Positives = 132/411 (32%), Gaps = 59/411 (14%)
Query: 171 VSGSRPEVAAKPALP-TQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTAR 229
++G +P +K LP +PA +Q+T +EEAG++ PP A
Sbjct: 84 LAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETG----KEEAGKEEPPPLTPPARCAAP 139
Query: 230 PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTA 289
V P RP S F AA TV ++ + +PR +
Sbjct: 140 GGVRKAPA-PFRPASERF------------AATTVEEILAK------MEQPRKEVLASPD 180
Query: 290 RFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAK 349
R GP R S L R E P+ P
Sbjct: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGW--SQEGPVKSP--------A 230
Query: 350 KIRERKEKMLSKPEMGSPRALVG----GSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSP 405
+ RE K + + S A G +S P++ PW SP+P
Sbjct: 231 ECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPW------------IPSSPAP 278
Query: 406 RLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPAS 465
G + A G C S E T + S P TP++
Sbjct: 279 SSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSA 338
Query: 466 PSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNE-- 523
PSAA P++G S G AE + P R P + L A+S
Sbjct: 339 PSAA-LPDEG--SRHTPSPGLPAEGAPEAP----RPSSPPPEVLEPHSLDQPPATSPRPL 391
Query: 524 VKYEKSAELSGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQ 574
++ + +L+ FP E+ K L + + + G L+ S+ E+
Sbjct: 392 IEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEK 442
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 57.8 bits (138), Expect = 1e-07
Identities = 128/572 (22%), Positives = 200/572 (34%), Gaps = 116/572 (20%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRM 110
+SPL++P + +P S+ D KS + T P G + AA +
Sbjct: 45 ESPLQTPTE-----DGSEEPGSETSDAKSTPTA--EDVTAPLVDEGAPGKQAAAQPHTEI 97
Query: 111 P-GLVGQEVGSGEGPR---------TSSPLFNKAV---FLRPSSSTMILFETTKSGPALG 157
P G +E G G+ P T P K V FLR + + P
Sbjct: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPG-A 156
Query: 158 KAVSEGAEEAKLGVSGSRPEVAA----KPAL-------------PTQKPAGTLPRSAPLS 200
+ EG EA SG+ PE P L P K AG R
Sbjct: 157 PLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
Query: 201 QDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGA 260
+ + E + QD PPSKAS +D RP P+ R ++I P P GA
Sbjct: 217 EVDEDRDVDESSPQDSPPSKASPAQD-GRP-----PQTAAREATSI------PGFPAEGA 264
Query: 261 AATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPR 320
PL +D ++ + A E GP+ G G + P
Sbjct: 265 I--------------------PLPVDFLSKVSTEIP-----ASEPDGPSVGRAKGQDAP- 298
Query: 321 AASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEMGSPRALVGGSSGVTP- 379
E H +E+ + +KE+ S+ +G RA G+ G P
Sbjct: 299 ------------LEFTFH------VEITPNV--QKEQAHSEEHLG--RAAFPGAPGEGPE 336
Query: 380 SNDQSPWEEKAKLD-PEPEKAAESPSPRLGRGLELAEVKSRVA--DGEAAAGGEWASRRS 436
+ S E+ + D PEP + + +PR + ++K+R+ + + ++ S
Sbjct: 337 ARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTS 396
Query: 437 VRKCISLFREDSTLA---LAVGSESPLATPASPSAAPEP---EKGVVSVQERIRGWTAES 490
R + L+ GS PL P+SP+ PEP K V SV R A+
Sbjct: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKE 456
Query: 491 SEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEPREKQKEGHSL 550
+ K + +A + ++A+ K + + + P+ + G+S
Sbjct: 457 MKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYS- 515
Query: 551 DGACIPRSPWKPGTLRDKSRQTEQKVSSNQDP 582
SP PGT +SR ++P
Sbjct: 516 -------SPGSPGTPGSRSRTPSLPTPPTREP 540
Score = 34.7 bits (78), Expect = 0.86
Identities = 68/288 (23%), Positives = 95/288 (32%), Gaps = 55/288 (19%)
Query: 25 EETLTRTYFLQA---GEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPV 81
EE L R F A G + P ++ L P+ P KP S+ +K+ +
Sbjct: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARM 378
Query: 82 PSLRPSSTGPSPSGG-LSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPS 140
S TG S +AK L NR P L + G P PS
Sbjct: 379 VSKSKDGTGSDDKKAKTSTRSSAKTLKNR-PCLSPKHPTPGSSDPLIQPSSPAVCPEPPS 437
Query: 141 SSTMILFETTKSGPALGKAVSEGAEEAKL-GVSG----SRPEVAAKPALPTQKPAGTLPR 195
S + T+++G S GA+E KL G G + P AA P Q A +P
Sbjct: 438 SPKHVSSVTSRTG-------SSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPA 490
Query: 196 SAPLSQDT-----KPPVPQEEAGQDHP--------------------------------P 218
P + T +PP + +G P P
Sbjct: 491 KTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 550
Query: 219 SKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGK 266
SS + + P P LK TE+++ Q PG G + K
Sbjct: 551 KSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ-PGGGKVQIINK 597
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 57.0 bits (136), Expect = 2e-07
Identities = 78/303 (25%), Positives = 111/303 (36%), Gaps = 36/303 (11%)
Query: 2 ATRVEVGSITPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLL 61
AT V G P +AV L + L + A AP + A P PA
Sbjct: 579 ATTVLQGVTLPPSAVAMLNT---PDGLVQPATPAAATGEAAPVLTVQPA--PQAPPAVST 633
Query: 62 PLPRLAPKPFSKEQDVKSPVPSLR--PSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVG 119
PLP +P +Q ++P P P +T P PS GL+ P K + + P +
Sbjct: 634 PLPLGLQQP-QAQQPPQAPTPQAAAPPQATTPQPSPGLASSPE-KIVLGQPPSATPTAIL 691
Query: 120 SGEG-------PRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVS 172
+ + R+ PL + L +S ++ PA V++GA G+
Sbjct: 692 TQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGA-----GLG 746
Query: 173 GSRPEVAAKPALPTQKPAG------------TLPRSAPLSQDTKPPVPQEEAGQDHPPSK 220
P+ A PA Q PA +LP APL P P PPS+
Sbjct: 747 PQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR 806
Query: 221 ASSV-EDTARPLVEPRPRLKRRP-VSAIFTESIQPQKPGPGA-AATVGKVPPTPPEKTWV 277
SV + P + P P + P + IF Q P P + A PP PP +
Sbjct: 807 PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS 866
Query: 278 RKP 280
+ P
Sbjct: 867 QPP 869
Score = 39.3 bits (90), Expect = 0.035
Identities = 62/284 (21%), Positives = 90/284 (31%), Gaps = 24/284 (8%)
Query: 37 GEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGG 96
G P + I+ A P + PA P+ + A SP P+ + + P G
Sbjct: 713 GPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPG 772
Query: 97 LSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPAL 156
S P+ L ++ P G+ P SP + PS + S P L
Sbjct: 773 PSSSPS---LPHQAP--------LGDSPHLPSPHPTRPPSRPPSRPQSV--SRPPSEPPL 819
Query: 157 GKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDH 216
A G+ + ++ P P P PL ++PP
Sbjct: 820 HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
Query: 217 PPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKV-----PPTP 271
PPS SS ++ P F S P K P T+ V PP P
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHK-SPTPPPTLHLVPEPAAPPPP 938
Query: 272 PEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAG 315
P +T+ P +ALL + SG + AG
Sbjct: 939 PPRTFQMVTTPF-----PALPQPKALLERFHQVPSGIILQNKAG 977
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 56.2 bits (134), Expect = 3e-07
Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 36/223 (16%)
Query: 61 LPLPRLAPKPFSKEQDVKSPVPSL------RPSSTGPSPSGGLSEEPAAKDLDNRMPGLV 114
+P PR P SK + PVPS P + G P G +P+ PG
Sbjct: 169 MPPPR--PDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR 226
Query: 115 GQEVGSG---EGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGV 171
G +G G + P +SS F+ L P+ S + + P +G S
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI--------- 277
Query: 172 SGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPL 231
R V P + P + PR + SQ PP P G P +S ++T
Sbjct: 278 --HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET---- 331
Query: 232 VEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
PRL +R +S S P P PG + G +PP P E+
Sbjct: 332 ----PRLPQRNLS---LSSSTPPLPSPGRS---GPLPPPPSER 364
Score = 43.5 bits (101), Expect = 0.002
Identities = 64/224 (28%), Positives = 85/224 (37%), Gaps = 29/224 (12%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRM 110
+SPL S + P L P P S+ D K P P P G PS P +N+
Sbjct: 237 QSPLSSSSPFSNRPPLPPTP-SRALDDKPPPP---PPPVGNRPSIHREAVPPPPPQNNKP 292
Query: 111 PGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLG 170
P V S P SS +A P S + GP S G +E
Sbjct: 293 P------VPSTPRPSASS----QAPPPPPPPS--------RPGPPPLPPSSSGNDETPRL 334
Query: 171 VSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV--PQEEAGQDHPPSKASSVEDTA 228
+ ++ P LP+ +G LP P S+ PPV P +G PP S T+
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLP--PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392
Query: 229 RPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPP 272
R L P+L R S + + P+ P P + G PP PP
Sbjct: 393 RAL-PATPQLPSR--SGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 56.2 bits (134), Expect = 3e-07
Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 36/223 (16%)
Query: 61 LPLPRLAPKPFSKEQDVKSPVPSL------RPSSTGPSPSGGLSEEPAAKDLDNRMPGLV 114
+P PR P SK + PVPS P + G P G +P+ PG
Sbjct: 169 MPPPR--PDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR 226
Query: 115 GQEVGSG---EGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGV 171
G +G G + P +SS F+ L P+ S + + P +G S
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI--------- 277
Query: 172 SGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPL 231
R V P + P + PR + SQ PP P G P +S ++T
Sbjct: 278 --HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET---- 331
Query: 232 VEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
PRL +R +S S P P PG + G +PP P E+
Sbjct: 332 ----PRLPQRNLS---LSSSTPPLPSPGRS---GPLPPPPSER 364
Score = 43.5 bits (101), Expect = 0.002
Identities = 64/224 (28%), Positives = 85/224 (37%), Gaps = 29/224 (12%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRM 110
+SPL S + P L P P S+ D K P P P G PS P +N+
Sbjct: 237 QSPLSSSSPFSNRPPLPPTP-SRALDDKPPPP---PPPVGNRPSIHREAVPPPPPQNNKP 292
Query: 111 PGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLG 170
P V S P SS +A P S + GP S G +E
Sbjct: 293 P------VPSTPRPSASS----QAPPPPPPPS--------RPGPPPLPPSSSGNDETPRL 334
Query: 171 VSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV--PQEEAGQDHPPSKASSVEDTA 228
+ ++ P LP+ +G LP P S+ PPV P +G PP S T+
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLP--PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392
Query: 229 RPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPP 272
R L P+L R S + + P+ P P + G PP PP
Sbjct: 393 RAL-PATPQLPSR--SGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 55.8 bits (133), Expect = 4e-07
Identities = 57/276 (20%), Positives = 104/276 (37%), Gaps = 15/276 (5%)
Query: 1518 SRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSS 1577
+ + TE ++ + E + G E+ + GE P A S K+ S S
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 1578 QTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDA-CPEKRVDDFSFIDQTS 1636
E S + + +S + S +S E PP+A PEK ++
Sbjct: 527 PAEAKSPEKE-----EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581
Query: 1637 VLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDSTEEKSP 1696
S K + ++ ++ S +E++SP+++E + K + KSP
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 1697 RKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAPQPK 1756
KEE+ E A E+ P++ + +KA+ + SP + A P+
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKA-------KSPVKAEAKSPEKAKSP--VKAEAKSPE 692
Query: 1757 SPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKE 1792
KSP + S + ++ +S E + +KE
Sbjct: 693 KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Score = 50.8 bits (120), Expect = 1e-05
Identities = 127/582 (21%), Positives = 198/582 (34%), Gaps = 82/582 (14%)
Query: 21 EMGKEETLTRTYFLQAGEA-SGAPPARIL-----EAKSPLRSPARLLPLPRLAPKPFSKE 74
E GKEE + GE + +PPA EAKSP++ A+ P A P ++
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS---PAEAKSP--EK 535
Query: 75 QDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKA 134
++ KSP P P AK S E SP K+
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAK---------------SPEKEEAKSPAEVKS 580
Query: 135 VFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLP 194
KA S EEAK PE A P ++
Sbjct: 581 P---------------------EKAKSPAKEEAKSPAEAKSPEKAKSPV--KEEAKSPAE 617
Query: 195 RSAPLSQDTKPPVPQEEAGQDHPPSK--ASSVEDTARPLVE--PRPRLKRRPVSAIFTES 250
+P+ ++ K P + + P+K A S E P E P + PV A E+
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA---EA 674
Query: 251 IQPQK-PGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPT 309
P+K P A P K + P + ++ E V +E P
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP- 733
Query: 310 AGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEMGSPRA 369
E+ ++ K + KA++P LD K ++E +
Sbjct: 734 -------EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786
Query: 370 LVGGSSGVTPSNDQSPWEEKAKLDPEPE--KAAESPSP----RLGRGLELAEVKSRVADG 423
+P +SP +E AK PE E K E SP + +++ E + +
Sbjct: 787 SPVKEEVKSPEKAKSPLKEDAKA-PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 424 EAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATP-----ASPSAAPEPEKGVVS 478
+A A + ++ +K + +E + E + P + E +K V +
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 905
Query: 479 VQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPK 538
++ +AKP+ + + P A K S A E EK + E K
Sbjct: 906 PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK-AKEPSKPAEKKEAAPEKK-DTKEEKAK 963
Query: 539 EPREKQKEGHSL--DGACIPRSPWKPGTLR-DKSRQTEQKVS 577
+P EK K D + + P KP + +KS T+QK S
Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Score = 42.7 bits (99), Expect = 0.003
Identities = 77/390 (19%), Positives = 144/390 (36%), Gaps = 52/390 (13%)
Query: 1427 EARERRREQPKGRPSLTGENLEAKMGPCWWESGTGDSHKVLPRDLEKEDAPQEKERPLQQ 1486
E E+ ++ +G+ GE EA+ G +S + P K +E + P +
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE-AASPEKEAKSPVKEEAKSPAEA 530
Query: 1487 VSPVASVPWRSHSFCKDRRSGPFVDQLKQCFSRQPTEPKDTDTLVHEAGSQYGTWTEQCQ 1546
SP K+ P + + K EA S + + +
Sbjct: 531 KSPE-----------KEEAKSP---------AEVKSPEKAKSPAKEEAKSPPEAKSPEKE 570
Query: 1547 SGESLATESPDSSATSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRSTSVDH--SST 1604
+S A A S K+ S + S + + ++ + +S + S
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630
Query: 1605 DLESTDGMEGPPPPDA-CPEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSL 1663
+++S + + P +A PEK ++ K+ V+ +S +A +
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSP----EKEEAKSPEKAKSPVKAEAKSPEKA--KSPV 684
Query: 1664 RRSRFSESESRSPLEDETDNTWMFKDSTEEKSPRKEES-----------DEEETASKAER 1712
+ S +++SP+++E K + KSP KEE+ +E +T KA +
Sbjct: 685 KAEAKSPEKAKSPVKEEA------KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA-K 737
Query: 1713 TPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAPQPKSP---KSPFQPGVLGS 1769
+PV + P P K K PE +P + + +P K P KSP + V
Sbjct: 738 SPVKEEAKSPE-KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796
Query: 1770 RVLPSSMDKDERSDEPSPQWLKELKSKKRQ 1799
S + +D ++ E +E+KS ++
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826
Score = 41.6 bits (96), Expect = 0.007
Identities = 80/430 (18%), Positives = 142/430 (33%), Gaps = 53/430 (12%)
Query: 1347 ESKPSGREDPGSGVRVSPKSPPTDQKKGTPR--KSTGRGEEDSVAQWGDHPRDCGRVPLD 1404
+ + G E+ G KSPP ++ + KS + E S A+ ++ + P +
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 1405 IKRAYSEKGPPANIREGLSIMHEARERRREQPKGRPSLTGENLEAKMGPCWWESGTGDSH 1464
+K K P +E+ K P E P +S
Sbjct: 544 VKSPEKAKSPA-----------------KEEAKSPPEAKSPEKEEAKSPAEVKS----PE 582
Query: 1465 KVLPRDLEKEDAPQEKERPLQQVSPV---ASVPWRSHSFCKDRRSGPFVDQLKQCFSRQP 1521
K E+ +P E + P + SPV A P + S K+ P + +
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642
Query: 1522 TEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSSQTEP 1581
E + + E+ +S +SP+ + + + + S + + E
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 1582 TSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLD-- 1639
S +++ + S E E P K + ++ LD
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762
Query: 1640 SSALKTRVQLSKRS-------RRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDSTE 1692
S KT + RS + ++P+ ++ S +++SPL+++ E
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVK----SPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 1693 E-KSPRKEESD-------------EEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHK 1738
E KSP KEE EEE A +T + P + K + K
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Query: 1739 RPEVDSPGET 1748
P V+ P E+
Sbjct: 879 EPAVEKPKES 888
Score = 34.7 bits (78), Expect = 0.86
Identities = 78/325 (24%), Positives = 119/325 (36%), Gaps = 57/325 (17%)
Query: 303 DEGSGPTAGDMAGLERP-RAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRER---KEKM 358
+E P A + A E+ ++ K + +A++P + EV + + KE+
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 359 LSKPEMGSPRALVGGSSGV--TPSNDQSPWEEKAKLDPE---PEKA-----------AES 402
S PE SP S +P +SP +E+AK E PEKA AE+
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618
Query: 403 PSPRLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLAT 462
SP AEVKS E A +S K S +E++ ++SP+
Sbjct: 619 KSPVKEEAKSPAEVKS----PEKAKSPTKEEAKSPEKAKSPEKEEA--KSPEKAKSPVKA 672
Query: 463 PA-SPSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASS 521
A SP A P K E+ + E +++ PE + + S + K
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS-PEKAKSPVKEEAKSPEKAK-------- 723
Query: 522 NEVKYEKSAELSGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQD 581
+ VK E + P + K E +SP K TL KS + +
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEK--------AKSPEKAKTLDVKSPEAKTPAKE--- 772
Query: 582 PDSCRGGSSVEAPCPSDVTPEDDRS 606
EA P+D PE +S
Sbjct: 773 ----------EARSPADKFPEKAKS 787
Score = 33.1 bits (74), Expect = 2.5
Identities = 56/238 (23%), Positives = 86/238 (36%), Gaps = 31/238 (13%)
Query: 49 EAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDN 108
E KSP ++ + L + K K+++VKSPV P +EP K +
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV------KEEEKPQEVKVKEPPKKAEEE 845
Query: 109 RMPGL---------VGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKA 159
+ P +E E P+ + +P S + E K K
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV---EAKKEEAEDKKK 902
Query: 160 VSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPS 219
V +EA V AKP T+ A P A + +KP +E A P
Sbjct: 903 VPTPEKEAPAKVEVKED---AKPKEKTE-VAKKEPDDAKAKEPSKPAEKKEAA----PEK 954
Query: 220 KASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAA---ATVGKVPPTPPEK 274
K + E +P E +P+ + + T S +P KP A ++ + PPEK
Sbjct: 955 KDTKEEKAKKP--EEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 32.0 bits (71), Expect = 5.6
Identities = 105/583 (18%), Positives = 206/583 (35%), Gaps = 84/583 (14%)
Query: 721 ENPPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPA 780
++PP + P + V E S A + +PE++ +S +K + ++
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE-----EAKSPAEVKSPEKAKSPAKE 556
Query: 781 DLECGLEGQAGSVQRASLIWEARGMPEASGP-KFGGNCPFPKWTGGAVVSSHKATVAVSE 839
+ + E ++ + A E + +A P K P S KA V E
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP------AEAKSPEKAKSPVKE 610
Query: 840 EHCAPGATSVRAIKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQA 899
E +P + A ++ + PE A+S A+ P + P P +++
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA--KSPEKEEAKSPEKAKS 668
Query: 900 RTHPDAFAVQKGPFIVAAREGDPGPAQVP--QPAVRMRKAGAMDQRMDRWRRRTLPPNVK 957
+A + +K V A P A+ P + A KA + + + + P VK
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP-VK 727
Query: 958 FDTFSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQTSPAVKQ 1017
+ + PE + SP + P+ + + + ++ + +T +
Sbjct: 728 EE---AKTPEKAK----------SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 1018 GSPVE--PKATFFAVTYQIPNTQKAKGVVLSGAESLLEHSRKITPPSSPHSLTSTLVSLG 1075
SP + P+ V ++ + +KAK + A++ + K SP +
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP---------VK 825
Query: 1076 HEEALEMAGSKNWMKGREHENASILKTLKPTDRPSSLGAWSLDPFNGRIIDVDALWSHRG 1135
EE + K K E E A T K ++ S
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAP--ATPKTEEKKDS-----------------------K 860
Query: 1136 SEDGPRPQSNWKESANKMSPSGGAPQTTPTLRSRPKDLPVRRKTDVISDTFPGKIRDGYR 1195
E+ P+ ++ + K P+ P+ + + ++ ++ ++K P K+
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKES-KVEAKKEEAEDKKKVPTPEKEAPAKVE---- 915
Query: 1196 SSVLDIDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRERPVQLGGVEQRRRSLKEMPD 1255
+ DA E E++ K P +A+ + +P+ P + E++ + +E P
Sbjct: 916 ---VKEDAKPKEKTEVAKKEPDDAKAKEPS--KPAEKKEAAPEKKDTKEEKAKKPEEKPK 970
Query: 1256 TGGLWKPASSAEINHSFTPGLGKQLAETLETAMGT---KSSPP 1295
T A + E + + + K AE E + T S PP
Sbjct: 971 T-----EAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 55.5 bits (132), Expect = 5e-07
Identities = 134/590 (22%), Positives = 203/590 (34%), Gaps = 134/590 (22%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRM 110
+SPL++P + +P S+ D KS + T P G + AA +
Sbjct: 45 ESPLQTPTE-----DGSEEPGSETSDAKSTPTA--EDVTAPLVDEGAPGKQAAAQPHTEI 97
Query: 111 P-GLVGQEVGSGEGPR---------TSSPLFNKAV---FLRPSSSTMILFETTKSGPALG 157
P G +E G G+ P T P K V FLR + + P
Sbjct: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPG-A 156
Query: 158 KAVSEGAEEAKLGVSGSRPEVAA----KPAL-------------PTQKPAGTLPRSAPLS 200
+ EG EA SG+ PE P L P K AG R
Sbjct: 157 PLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
Query: 201 QDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGA 260
+ + E + QD PPSKAS +D RP P+ R ++I P P GA
Sbjct: 217 EVDEDRDVDESSPQDSPPSKASPAQD-GRP-----PQTAAREATSI------PGFPAEGA 264
Query: 261 AATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPR 320
PL +D ++ + A E GP+ G G + P
Sbjct: 265 I--------------------PLPVDFLSKVSTEIP-----ASEPDGPSVGRAKGQDAP- 298
Query: 321 AASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEMGSPRALVGGSSGVTP- 379
E H +E+ + +KE+ S+ +G RA G+ G P
Sbjct: 299 ------------LEFTFH------VEITPNV--QKEQAHSEEHLG--RAAFPGAPGEGPE 336
Query: 380 SNDQSPWEEKAKLD-PEPEKAAESPSPRLGRGLELAEVKSRVA--DGEAAAGGEWASRRS 436
+ S E+ + D PEP + + +PR + ++K+R+ + + ++ S
Sbjct: 337 ARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTS 396
Query: 437 VRKCISLFREDSTLA---LAVGSESPLATPASPSAAPEP---EKGVVSVQER-------- 482
R + L+ GS PL P+SP+ PEP K V SV R
Sbjct: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKE 456
Query: 483 --IRGWTAESSEAKPEVRRRTFQARPLSA--------DLTKLFSSSASSNEVKYEKSAEL 532
++G ++ A P Q +A K SSA+ + A
Sbjct: 457 MKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGP 516
Query: 533 SGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQKVSSNQDP 582
E + P+ + G+S SP PGT +SR ++P
Sbjct: 517 RSERGEPPKSGDRSGYS--------SPGSPGTPGSRSRTPSLPTPPTREP 558
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 51.6 bits (122), Expect = 7e-06
Identities = 105/536 (19%), Positives = 192/536 (35%), Gaps = 64/536 (11%)
Query: 37 GEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGG 96
G+A AP A+ + K ++PA P+ P K + + P ++ S +
Sbjct: 984 GQAPPAP-AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS------- 1035
Query: 97 LSEEPAAKDLDNRMP---------GLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILF 147
L+ EP L ++ L E+ G P FN + + F
Sbjct: 1036 LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS---KDPPNFNTCTECKNQVCNLCGF 1092
Query: 148 ETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV 207
T + + + + + +SG ++ P P+ A +P S
Sbjct: 1093 NPTPHLTEIQEWLCLNCQTQR-AISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVP 1151
Query: 208 PQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKV 267
PQ + + + E V+ +++ P + + K A+ + +
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
Query: 268 PPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGL-ERPRAASKLD 326
P P EK + + + R E K+ LL E PT D L E +A +
Sbjct: 1212 KPLPEEKKLIPEEEKI------RSEEKKPLL-----EEKKPTPEDKKLLPEAKTSAPEEQ 1260
Query: 327 RDCLVKAEAPLHDPDLDFLEVAKKIRERKE---KMLSKPEMGSPRALVGGSSGVTPS--- 380
+ L+K++ + + L+ K ++E K+ KM P G+P++L T +
Sbjct: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPS-GTPQSLPKEDDKTTKTIKE 1319
Query: 381 ----------NDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRVADGEAAAGGE 430
+ P +EK + + + + S P+ +GL S DG +++ GE
Sbjct: 1320 QPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS---DGISSSLGE 1376
Query: 431 WASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQERIRGWTAES 490
+ I +D L S S ++P+SPS + E V+S+ E A+
Sbjct: 1377 ------IPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 491 SEAKPEVRRRTFQARPLSADLTKLFSS----SASSNEVKYEKSAELSGEFPKEPRE 542
K +P + T+ S + S E+K E E F K+ ++
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK-ESQEERKDTFKKDSQQ 1485
Score = 45.4 bits (106), Expect = 5e-04
Identities = 252/1235 (20%), Positives = 407/1235 (32%), Gaps = 197/1235 (15%)
Query: 6 EVGSITPLTAVPGLGEMGKEETLTRTYFLQAG----EASGAPPARILEAKSPLRSPARLL 61
+VG+ PL PGL K T+T Q G A A P + ++ P L
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Query: 62 PLPRLAP-------KPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLV 114
P P P KP ++ P PS +P ST P P +P+ P
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPS--------PQQP 524
Query: 115 GQEVGSGEGPRTSSPLFNKAVFLRPSS--STMILFETTKSGPALGKAVSEGAEEAKLGVS 172
G + P ++ P + +PS+ ST + +T P VS A++ S
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP---S 581
Query: 173 GSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVE------- 225
P+ P T + +P A + T+ +P + V+
Sbjct: 582 QGLPKTIC-PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 226 --------DTARPLVEPRPRLKRRPV---SAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
D A P+P+LK PV SA+ S QPQ+ P A + PE
Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700
Query: 275 TWVRKPRPLSMDLTAR-FENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKA 333
+KP PL T + +A AD S P A + P S+ D+
Sbjct: 701 ---KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP-----APPKEPSVPSEQDK------ 746
Query: 334 EAPLHDPDLDFLEVAKKIRE--RKEKMLSKPEMGSPRALVGGSSGVTPSNDQSPWEEKAK 391
AP+ D ++ K + +KP++ S + TP +
Sbjct: 747 -APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS 805
Query: 392 LDPEPEKAAESPSPRLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLA 451
P EK + S + R +++ S + G + V+K +E+ A
Sbjct: 806 FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD--PVQK-----KEEPKKA 858
Query: 452 LAVGSESPLATPASPSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADL 511
S P A P P +P P G T + + P+ + Q+R S +L
Sbjct: 859 QTKMSPKPDAKP-MPKGSPTPPG-----PRPTAGQTVPTPQQSPKPQE---QSRRFSLNL 909
Query: 512 TKLFSSSASSNEVKYEKSAELSGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQ 571
+ + S E F + S G P S PG ++
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969
Query: 572 TEQKVSSNQDPDSCRGG-----------SSVEAPCPSDVTPEDDRSFQTVWATVFEHHVE 620
Q +S P S +AP + P+ +++ TV E
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA-----PTVKRTETE 1024
Query: 621 RHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWL--------GRDPPDM---TKLK 669
+ + + L+ P + ++ E P+PE L +DPP+ T+ K
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKL-EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECK 1083
Query: 670 KE--NSRGFD-NPETEKLGPTTLLNGELRPYHT----PLRDKYPLSENHNNNTFLKHLEN 722
+ N GF+ P ++ LN + + + +R P + E+
Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143
Query: 723 PPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPADL 782
+ P+ +V + V +EA + V L ++ LS++
Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEA-------EKVILEKVKETLSMEKIPPMVTTDQKQE 1196
Query: 783 ECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEEHC 842
E LE +AS + E + +PE E+
Sbjct: 1197 ESKLE-----KDKASALQEKKPLPE-------------------------------EKKL 1220
Query: 843 APGATSVRA-IKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQART 901
P +R+ K + E + PE + P P + S+ + R
Sbjct: 1221 IPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRV 1280
Query: 902 HPDAFAVQKGPFIVAAREGDPG--PAQVPQPAVRMRK---------AGAMDQRMDRWRRR 950
P VQ+G EG P P +P+ + K A +++ + +
Sbjct: 1281 APK--TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEK 1338
Query: 951 TLPPNVKFDTFSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQ 1010
T + K DT SS P+ SP G T Y S S+ S + +++ G +D
Sbjct: 1339 TEKEDDKSDTSSSQQPK-SPQ-GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDS 1396
Query: 1011 TSPAVKQGSPVEPKATFFAVTYQIPNTQKAKGVVLSGAESLL-----EHSRKITPPS--S 1063
S ++ SP P + K + VLS E+ E S K T P S
Sbjct: 1397 FS---QESSPSSPS-----------DLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS 1442
Query: 1064 PHSLTSTLVSLGHEEALEMAGSKNWMKGREHENASILKTLKPTDRPSSLG----AWSLDP 1119
P + E LE+ S+ +K + E K D PSS + +D
Sbjct: 1443 PEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDD 1502
Query: 1120 FNGRIIDVDALWSHRGSEDGPRPQSNWKESANKMS 1154
R D++ SE+ P PQ + S S
Sbjct: 1503 ITTRREPYDSVEESSESENSPVPQRKRRTSVGSSS 1537
Score = 45.1 bits (105), Expect = 6e-04
Identities = 67/274 (24%), Positives = 95/274 (34%), Gaps = 60/274 (21%)
Query: 21 EMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQD--VK 78
E GK E + + Q PP I + + P R P + PK S +Q +K
Sbjct: 199 EQGKPEGIIKPPLQQQ------PPKPIPKQQGPGRDPLQ----QDGTPKSISSQQPEKIK 248
Query: 79 SPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLR 138
S P GP+ + D P ++ GE + S P +K +
Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 139 PSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAP 198
P+ P A G E+++ G PA P +P+G A
Sbjct: 309 PT-------------PGKPPAQQPGHEKSQPG-----------PAKPPAQPSGLTKPLAQ 344
Query: 199 LSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGP 258
KPPV + G PP A+PL +P P +E ++PGP
Sbjct: 345 QPGTVKPPV--QPPGTTKPP---------AQPLGPAKP-----PAQQTGSEKPSSEQPGP 388
Query: 259 GAAAT---VGKVP-----PTPPEKTWVRKPRPLS 284
A A VGK P P P V P+PL+
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
Score = 36.2 bits (82), Expect = 0.30
Identities = 71/295 (24%), Positives = 101/295 (34%), Gaps = 50/295 (16%)
Query: 14 TAVPG-----LGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRL-A 67
TA+P L ++ +EE R A G P + A + S R L
Sbjct: 35 TAIPAGMEADLSQLSEEER--RQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHP 92
Query: 68 PKPFSKEQDVKSPV-PSLRPSST-----------GPSPSG-GLSEEPAAKDL-----DNR 109
PK + D P P L S T G SPS L E + DL +
Sbjct: 93 PKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSM 152
Query: 110 MPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKL 169
MPG + EV + + FN + S ++ ETTK + K +G E +
Sbjct: 153 MPGFLS-EVNALSAVSSVVNKFNPFDLISDSEASQE--ETTKKQKVVQK--EQGKPEGII 207
Query: 170 GVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV---PQEEAGQDHPPSKASSVED 226
+P + +P P K G P PL QD P Q E + PP ++
Sbjct: 208 -----KPPLQQQPPKPIPKQQG--PGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260
Query: 227 TAR---------PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPP 272
+ PL R + + + ES++P P P P PP
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPP 315
Score = 35.0 bits (79), Expect = 0.66
Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 5/111 (4%)
Query: 1696 PRKEESDEEETASKAERTPVSHPQRMPAFP--GMDPAVLKA-QLHKRPEVDSPGETPSWA 1752
P E+D + + + R + R P + PA ++ +H++ E+DS P +
Sbjct: 38 PAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDS-SHPPKQS 96
Query: 1753 PQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKELKSKKRQSLYE 1803
+P P P QPG+ SR + +++ SP + +SK R L E
Sbjct: 97 GRPPDPGRPAQPGLSKSRT-TDTFRSEQKLPGRSPSTISLKESKSRTDLKE 146
Score = 33.9 bits (76), Expect = 1.5
Identities = 79/438 (18%), Positives = 153/438 (34%), Gaps = 54/438 (12%)
Query: 1301 PSAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGV 1360
P APS P+P + + K + K + AE + +
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTE---AEKVILEKVKETLSM 1182
Query: 1361 RVSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIR- 1419
P TDQK+ + + + ++ + P + +P + K EK P +
Sbjct: 1183 EKIPPMVTTDQKQEESKLE--KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK 1240
Query: 1420 ---EGLSIMHEAR-----ERRREQPKGRPSLTGENLEAKMGPCWWESGTGDSHKV----- 1466
E ++ EA+ E++ + K + + E LE ++ P + G K+
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPS 1300
Query: 1467 -LPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSFCKDRRSGPFVDQLKQCFSRQPTEPK 1525
P+ L KED K Q P + P DQ++ + E
Sbjct: 1301 GTPQSLPKEDDKTTKTIKEQPQPPCTAKP----------------DQVEPGKEKTEKEDD 1344
Query: 1526 DTDTLVHEAGSQYGTWTEQCQSGESLAT---ESPDSSATSTRKQPPSSRLSSLSSQTEPT 1582
+DT + ++ S + +++ E P T + + S S ++ P+
Sbjct: 1345 KSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS 1404
Query: 1583 SAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLDSSA 1642
S D S +ST L + P + PE+ D + L+ +
Sbjct: 1405 SPSDLAKLESTVLSILEAQAST-LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1643 LKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDSTEEKSPRKEESD 1702
+ ++ S+ R+ + +S+ + D+ + ++ + R+E D
Sbjct: 1464 SEEEIKESQEERKDT-----------FKKDSQQDIPSSKDHKEK-SEFVDDITTRREPYD 1511
Query: 1703 EEETASKAERTPVSHPQR 1720
E +S++E +PV PQR
Sbjct: 1512 SVEESSESENSPV--PQR 1527
Score = 33.5 bits (75), Expect = 1.9
Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 27/147 (18%)
Query: 167 AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV-PQEEAGQDHPPSKASSVE 225
+ L +S P P P P P P KP + P+++ P + A+ +
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLF 2456
Query: 226 D-----------------------TARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAA 262
D TA P V P+P P +FT +P KP
Sbjct: 2457 DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP--SSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 263 TVGKVPPTPPEKTWVRKPRPLSMDLTA 289
+ ++P T + T + P+P + LT+
Sbjct: 2515 VIPQLPTTTQKPTDIH-PKPTGLSLTS 2540
Score = 33.1 bits (74), Expect = 2.5
Identities = 49/193 (25%), Positives = 71/193 (36%), Gaps = 25/193 (12%)
Query: 25 EETLTRTYFLQAGEASGAPPARILEAKSPLRS--PARLLPLPRLAPKPF--SKEQDVKSP 80
+E L+ TYF PA L + SP S PA+ P+PF S D+ +
Sbjct: 2353 KEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAK--------PRPFFRSSSLDISAQ 2404
Query: 81 VPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGP-RTSSPLFN------K 133
P P P P P + P ++ ++ + P T++PLF+
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 134 AVFLRPSSSTMILFETTKSGPALGKAVS-EGAEEAKLGVSGSRPEVAAKPALP-----TQ 187
LR + + TT P K S S+P +A KP +P TQ
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ 2524
Query: 188 KPAGTLPRSAPLS 200
KP P+ LS
Sbjct: 2525 KPTDIHPKPTGLS 2537
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 51.6 bits (122), Expect = 7e-06
Identities = 105/536 (19%), Positives = 192/536 (35%), Gaps = 64/536 (11%)
Query: 37 GEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGG 96
G+A AP A+ + K ++PA P+ P K + + P ++ S +
Sbjct: 984 GQAPPAP-AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS------- 1035
Query: 97 LSEEPAAKDLDNRMP---------GLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILF 147
L+ EP L ++ L E+ G P FN + + F
Sbjct: 1036 LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS---KDPPNFNTCTECKNQVCNLCGF 1092
Query: 148 ETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV 207
T + + + + + +SG ++ P P+ A +P S
Sbjct: 1093 NPTPHLTEIQEWLCLNCQTQR-AISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVP 1151
Query: 208 PQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKV 267
PQ + + + E V+ +++ P + + K A+ + +
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
Query: 268 PPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGL-ERPRAASKLD 326
P P EK + + + R E K+ LL E PT D L E +A +
Sbjct: 1212 KPLPEEKKLIPEEEKI------RSEEKKPLL-----EEKKPTPEDKKLLPEAKTSAPEEQ 1260
Query: 327 RDCLVKAEAPLHDPDLDFLEVAKKIRERKE---KMLSKPEMGSPRALVGGSSGVTPS--- 380
+ L+K++ + + L+ K ++E K+ KM P G+P++L T +
Sbjct: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPS-GTPQSLPKEDDKTTKTIKE 1319
Query: 381 ----------NDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRVADGEAAAGGE 430
+ P +EK + + + + S P+ +GL S DG +++ GE
Sbjct: 1320 QPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS---DGISSSLGE 1376
Query: 431 WASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQERIRGWTAES 490
+ I +D L S S ++P+SPS + E V+S+ E A+
Sbjct: 1377 ------IPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 491 SEAKPEVRRRTFQARPLSADLTKLFSS----SASSNEVKYEKSAELSGEFPKEPRE 542
K +P + T+ S + S E+K E E F K+ ++
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK-ESQEERKDTFKKDSQQ 1485
Score = 45.4 bits (106), Expect = 5e-04
Identities = 252/1235 (20%), Positives = 407/1235 (32%), Gaps = 197/1235 (15%)
Query: 6 EVGSITPLTAVPGLGEMGKEETLTRTYFLQAG----EASGAPPARILEAKSPLRSPARLL 61
+VG+ PL PGL K T+T Q G A A P + ++ P L
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Query: 62 PLPRLAP-------KPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLV 114
P P P KP ++ P PS +P ST P P +P+ P
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPS--------PQQP 524
Query: 115 GQEVGSGEGPRTSSPLFNKAVFLRPSS--STMILFETTKSGPALGKAVSEGAEEAKLGVS 172
G + P ++ P + +PS+ ST + +T P VS A++ S
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP---S 581
Query: 173 GSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVE------- 225
P+ P T + +P A + T+ +P + V+
Sbjct: 582 QGLPKTIC-PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 226 --------DTARPLVEPRPRLKRRPV---SAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
D A P+P+LK PV SA+ S QPQ+ P A + PE
Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700
Query: 275 TWVRKPRPLSMDLTAR-FENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKA 333
+KP PL T + +A AD S P A + P S+ D+
Sbjct: 701 ---KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP-----APPKEPSVPSEQDK------ 746
Query: 334 EAPLHDPDLDFLEVAKKIRE--RKEKMLSKPEMGSPRALVGGSSGVTPSNDQSPWEEKAK 391
AP+ D ++ K + +KP++ S + TP +
Sbjct: 747 -APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS 805
Query: 392 LDPEPEKAAESPSPRLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLA 451
P EK + S + R +++ S + G + V+K +E+ A
Sbjct: 806 FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD--PVQK-----KEEPKKA 858
Query: 452 LAVGSESPLATPASPSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADL 511
S P A P P +P P G T + + P+ + Q+R S +L
Sbjct: 859 QTKMSPKPDAKP-MPKGSPTPPG-----PRPTAGQTVPTPQQSPKPQE---QSRRFSLNL 909
Query: 512 TKLFSSSASSNEVKYEKSAELSGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQ 571
+ + S E F + S G P S PG ++
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969
Query: 572 TEQKVSSNQDPDSCRGG-----------SSVEAPCPSDVTPEDDRSFQTVWATVFEHHVE 620
Q +S P S +AP + P+ +++ TV E
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA-----PTVKRTETE 1024
Query: 621 RHTVADQSGRCLSTTPPGDMAHARVSEPRPRPEMGSWL--------GRDPPDM---TKLK 669
+ + + L+ P + ++ E P+PE L +DPP+ T+ K
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKL-EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECK 1083
Query: 670 KE--NSRGFD-NPETEKLGPTTLLNGELRPYHT----PLRDKYPLSENHNNNTFLKHLEN 722
+ N GF+ P ++ LN + + + +R P + E+
Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143
Query: 723 PPTSQRIEPRYDIVHAVGERVHSEAISPAPEEKAVTLRSLRSWLSLKDRQLSQEVTPADL 782
+ P+ +V + V +EA + V L ++ LS++
Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEA-------EKVILEKVKETLSMEKIPPMVTTDQKQE 1196
Query: 783 ECGLEGQAGSVQRASLIWEARGMPEASGPKFGGNCPFPKWTGGAVVSSHKATVAVSEEHC 842
E LE +AS + E + +PE E+
Sbjct: 1197 ESKLE-----KDKASALQEKKPLPE-------------------------------EKKL 1220
Query: 843 APGATSVRA-IKAAIWESQHEGPEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQART 901
P +R+ K + E + PE + P P + S+ + R
Sbjct: 1221 IPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRV 1280
Query: 902 HPDAFAVQKGPFIVAAREGDPG--PAQVPQPAVRMRK---------AGAMDQRMDRWRRR 950
P VQ+G EG P P +P+ + K A +++ + +
Sbjct: 1281 APK--TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEK 1338
Query: 951 TLPPNVKFDTFSSLVPEDSPHVGHRRTDYVSPTASALRKPQLSHYRVETQEVNPGASRDQ 1010
T + K DT SS P+ SP G T Y S S+ S + +++ G +D
Sbjct: 1339 TEKEDDKSDTSSSQQPK-SPQ-GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDS 1396
Query: 1011 TSPAVKQGSPVEPKATFFAVTYQIPNTQKAKGVVLSGAESLL-----EHSRKITPPS--S 1063
S ++ SP P + K + VLS E+ E S K T P S
Sbjct: 1397 FS---QESSPSSPS-----------DLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS 1442
Query: 1064 PHSLTSTLVSLGHEEALEMAGSKNWMKGREHENASILKTLKPTDRPSSLG----AWSLDP 1119
P + E LE+ S+ +K + E K D PSS + +D
Sbjct: 1443 PEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDD 1502
Query: 1120 FNGRIIDVDALWSHRGSEDGPRPQSNWKESANKMS 1154
R D++ SE+ P PQ + S S
Sbjct: 1503 ITTRREPYDSVEESSESENSPVPQRKRRTSVGSSS 1537
Score = 45.1 bits (105), Expect = 6e-04
Identities = 67/274 (24%), Positives = 95/274 (34%), Gaps = 60/274 (21%)
Query: 21 EMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQD--VK 78
E GK E + + Q PP I + + P R P + PK S +Q +K
Sbjct: 199 EQGKPEGIIKPPLQQQ------PPKPIPKQQGPGRDPLQ----QDGTPKSISSQQPEKIK 248
Query: 79 SPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLR 138
S P GP+ + D P ++ GE + S P +K +
Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 139 PSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAP 198
P+ P A G E+++ G PA P +P+G A
Sbjct: 309 PT-------------PGKPPAQQPGHEKSQPG-----------PAKPPAQPSGLTKPLAQ 344
Query: 199 LSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGP 258
KPPV + G PP A+PL +P P +E ++PGP
Sbjct: 345 QPGTVKPPV--QPPGTTKPP---------AQPLGPAKP-----PAQQTGSEKPSSEQPGP 388
Query: 259 GAAAT---VGKVP-----PTPPEKTWVRKPRPLS 284
A A VGK P P P V P+PL+
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
Score = 36.2 bits (82), Expect = 0.30
Identities = 71/295 (24%), Positives = 101/295 (34%), Gaps = 50/295 (16%)
Query: 14 TAVPG-----LGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRL-A 67
TA+P L ++ +EE R A G P + A + S R L
Sbjct: 35 TAIPAGMEADLSQLSEEER--RQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHP 92
Query: 68 PKPFSKEQDVKSPV-PSLRPSST-----------GPSPSG-GLSEEPAAKDL-----DNR 109
PK + D P P L S T G SPS L E + DL +
Sbjct: 93 PKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSM 152
Query: 110 MPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKL 169
MPG + EV + + FN + S ++ ETTK + K +G E +
Sbjct: 153 MPGFLS-EVNALSAVSSVVNKFNPFDLISDSEASQE--ETTKKQKVVQK--EQGKPEGII 207
Query: 170 GVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV---PQEEAGQDHPPSKASSVED 226
+P + +P P K G P PL QD P Q E + PP ++
Sbjct: 208 -----KPPLQQQPPKPIPKQQG--PGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260
Query: 227 TAR---------PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPP 272
+ PL R + + + ES++P P P P PP
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPP 315
Score = 35.0 bits (79), Expect = 0.66
Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 5/111 (4%)
Query: 1696 PRKEESDEEETASKAERTPVSHPQRMPAFP--GMDPAVLKA-QLHKRPEVDSPGETPSWA 1752
P E+D + + + R + R P + PA ++ +H++ E+DS P +
Sbjct: 38 PAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDS-SHPPKQS 96
Query: 1753 PQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKELKSKKRQSLYE 1803
+P P P QPG+ SR + +++ SP + +SK R L E
Sbjct: 97 GRPPDPGRPAQPGLSKSRT-TDTFRSEQKLPGRSPSTISLKESKSRTDLKE 146
Score = 33.9 bits (76), Expect = 1.5
Identities = 79/438 (18%), Positives = 153/438 (34%), Gaps = 54/438 (12%)
Query: 1301 PSAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGV 1360
P APS P+P + + K + K + AE + +
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTE---AEKVILEKVKETLSM 1182
Query: 1361 RVSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIR- 1419
P TDQK+ + + + ++ + P + +P + K EK P +
Sbjct: 1183 EKIPPMVTTDQKQEESKLE--KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK 1240
Query: 1420 ---EGLSIMHEAR-----ERRREQPKGRPSLTGENLEAKMGPCWWESGTGDSHKV----- 1466
E ++ EA+ E++ + K + + E LE ++ P + G K+
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPS 1300
Query: 1467 -LPRDLEKEDAPQEKERPLQQVSPVASVPWRSHSFCKDRRSGPFVDQLKQCFSRQPTEPK 1525
P+ L KED K Q P + P DQ++ + E
Sbjct: 1301 GTPQSLPKEDDKTTKTIKEQPQPPCTAKP----------------DQVEPGKEKTEKEDD 1344
Query: 1526 DTDTLVHEAGSQYGTWTEQCQSGESLAT---ESPDSSATSTRKQPPSSRLSSLSSQTEPT 1582
+DT + ++ S + +++ E P T + + S S ++ P+
Sbjct: 1345 KSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS 1404
Query: 1583 SAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLDSSA 1642
S D S +ST L + P + PE+ D + L+ +
Sbjct: 1405 SPSDLAKLESTVLSILEAQAST-LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1643 LKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDSTEEKSPRKEESD 1702
+ ++ S+ R+ + +S+ + D+ + ++ + R+E D
Sbjct: 1464 SEEEIKESQEERKDT-----------FKKDSQQDIPSSKDHKEK-SEFVDDITTRREPYD 1511
Query: 1703 EEETASKAERTPVSHPQR 1720
E +S++E +PV PQR
Sbjct: 1512 SVEESSESENSPV--PQR 1527
Score = 33.5 bits (75), Expect = 1.9
Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 27/147 (18%)
Query: 167 AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPV-PQEEAGQDHPPSKASSVE 225
+ L +S P P P P P P KP + P+++ P + A+ +
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLF 2456
Query: 226 D-----------------------TARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAA 262
D TA P V P+P P +FT +P KP
Sbjct: 2457 DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP--SSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 263 TVGKVPPTPPEKTWVRKPRPLSMDLTA 289
+ ++P T + T + P+P + LT+
Sbjct: 2515 VIPQLPTTTQKPTDIH-PKPTGLSLTS 2540
Score = 33.1 bits (74), Expect = 2.5
Identities = 49/193 (25%), Positives = 71/193 (36%), Gaps = 25/193 (12%)
Query: 25 EETLTRTYFLQAGEASGAPPARILEAKSPLRS--PARLLPLPRLAPKPF--SKEQDVKSP 80
+E L+ TYF PA L + SP S PA+ P+PF S D+ +
Sbjct: 2353 KEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAK--------PRPFFRSSSLDISAQ 2404
Query: 81 VPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGP-RTSSPLFN------K 133
P P P P P + P ++ ++ + P T++PLF+
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 134 AVFLRPSSSTMILFETTKSGPALGKAVS-EGAEEAKLGVSGSRPEVAAKPALP-----TQ 187
LR + + TT P K S S+P +A KP +P TQ
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ 2524
Query: 188 KPAGTLPRSAPLS 200
KP P+ LS
Sbjct: 2525 KPTDIHPKPTGLS 2537
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 51.2 bits (121), Expect = 9e-06
Identities = 70/288 (24%), Positives = 108/288 (37%), Gaps = 40/288 (13%)
Query: 1526 DTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSSQTEPTSAG 1585
DT + H + SQ GT + ++S DS + T ++PPSS + Q+ P
Sbjct: 406 DTSSKTH-SNSQQGT--SSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVA 462
Query: 1586 DQYDCSRDQRSTSVDHSSTDLE----STDGMEGPPPPDACPEKR---VDDFSFIDQTSVL 1638
+ S + STS SS+D E S+D E P PE + + + + +
Sbjct: 463 SAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKV 522
Query: 1639 DSSALKTRVQLSKRSRRRAPISHSLRRSRFSE--SESRSPLEDETDNTWMFKDSTE---- 1692
A S RR P S S S+ SES+ P +
Sbjct: 523 SQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGK 582
Query: 1693 ---EKSPRKEESDEEET-ASKAERTPVSHPQRMPA--------FPGMDPAVLKAQLHK-R 1739
+KSP ++E + +T +K + PV R + PG+ P + Q K +
Sbjct: 583 RSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDK 642
Query: 1740 PEVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSP 1787
P+V + G + A P P PSS K +S P+P
Sbjct: 643 PKVKTKGRPRAAASNEPKPAVP-----------PSSEKKKHKSSLPAP 679
Score = 33.5 bits (75), Expect = 1.9
Identities = 107/487 (21%), Positives = 164/487 (33%), Gaps = 66/487 (13%)
Query: 80 PVPSLRPSSTGPSPSGGLSEEPAA---------KDLDNRMPGLVGQEVGSGEGPRTSSPL 130
P+PSL S GP S L+++ K D R G V R SPL
Sbjct: 142 PMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPL 201
Query: 131 FNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPA 190
+ + P S +T K V + +K P+ A + P
Sbjct: 202 ISLPSPVPPLSPIHSNQQTLPRTQGSSK-VHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ 260
Query: 191 GTLPRSA-PLSQDTKPP-VPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFT 248
+L A P SQ PP +P + P+ D P LK P
Sbjct: 261 DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLP------ 314
Query: 249 ESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGP 308
E + Q T K P K + K + S + + N+ + ++ E +
Sbjct: 315 EDYRQQ--------TFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHS 366
Query: 309 TAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKE-KMLSKPEMGSP 367
+ + P A ++ P P D V+ + +K+ SK S
Sbjct: 367 WPPPLTAIHTPSTAE--------PSKFPF--PTKDSQHVSSVTQNQKQYDTSSKTHSNSQ 416
Query: 368 RALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAES---PSPRLGRGLELAEVKSRVADGE 424
+ G+S + + Q E + + PEK S PS +A S A+ E
Sbjct: 417 Q----GTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472
Query: 425 AAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQERIR 484
+ + + +S S E+ PL TP APEPE + + ++
Sbjct: 473 STSDSDSSSDSESESSSSDSEEN----------EPLETP-----APEPEPPTTN-KWQLD 516
Query: 485 GWTAESSE--AKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKS--AELSGEFPKEP 540
W + S+ A PE R T P +K S SA+S E K + S + P+ P
Sbjct: 517 NWLTKVSQPAAPPEGPRST--EPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAP 574
Query: 541 REKQKEG 547
E G
Sbjct: 575 PEAPHPG 581
Score = 32.3 bits (72), Expect = 4.3
Identities = 66/313 (21%), Positives = 107/313 (34%), Gaps = 49/313 (15%)
Query: 1060 PPSSPHSLTSTLVSLGHEEALEMAGSKNWMKGREHENASI---------LKTLKPTDRPS 1110
PPS+P SL + S H + E + + + E+ S L+T P P
Sbjct: 450 PPSAPQSLPEPVAS-AHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPP 508
Query: 1111 SLGAWSLDPFNGRIIDVDALWSHRGSEDGPRPQSNWKESANKMSPSGGAPQTTPTLRSRP 1170
+ W LD + ++ A S + PR K G + T S
Sbjct: 509 TTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESK---------GSSDSATSQEHSES 559
Query: 1171 KDLPVRRKTDVISDTFPGKIRDGYRSSVLDIDALMAEYQELSLKVPGEAQERRSPTVEPS 1230
KD P + + P G RS K P + + + TV
Sbjct: 560 KDPPPKSSSKAPRAP-PEAPHPGKRSCQ---------------KSPAQQEPPQRQTV--G 601
Query: 1231 TLPRERPVQLGGVEQRRRSLKEMPDTGGLWKPASSAEINHSFTPGLGKQLAETLETAMGT 1290
T ++PV+ R SL+ + G L P S + P + +T
Sbjct: 602 TKQPKKPVKASARAGSRTSLQGEREPGLL--PYGSRDQTSKDKPKV-----KTKGRPRAA 654
Query: 1291 KSSPPFWALPPSAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKP 1350
S+ P A+PPS+ +++ P P+ A+D+ + +H + ++
Sbjct: 655 ASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFA-----LVPLTES 709
Query: 1351 SGREDPGSGVRVS 1363
G GSG R S
Sbjct: 710 QGPPHSGSGSRTS 722
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 51.2 bits (121), Expect = 9e-06
Identities = 102/452 (22%), Positives = 156/452 (34%), Gaps = 69/452 (15%)
Query: 120 SGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVA 179
+GEGP T+ P ++ F+ ++ P L A++ G G P
Sbjct: 571 NGEGPATAGP-------------RLLTFQGSELSPELQAAMAGG---------GPEPLPL 608
Query: 180 AKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARP--LVEPRPR 237
P+Q+ G R + SQ+ P PQ G PP + + E T RP L P
Sbjct: 609 PPARSPSQESIGARSRGSGHSQEQ--PAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPG 666
Query: 238 LKRRPVSAIFTESIQPQKPGPG-------AAATVGKVPPTPPEKTWVRKPRPLSMDLTAR 290
P ++ + P P PG A + + P TPP+ +P+ S L +R
Sbjct: 667 QGPPPYVFMYPQG-SPSSPAPGPPPGAPWAFSYLAGPPATPPDPP---RPKRRSHSL-SR 721
Query: 291 FENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKK 350
E A+ G T G A L R + R LV+ + ++
Sbjct: 722 PGPTEGDAEGEAEGPVGSTLGSYATLTR-----RPGRSALVRTSPSVTPTPARGTPRSQS 776
Query: 351 IRERKEKMLSKPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDP------EPEKAAESPS 404
R + P + V G S P D+SP ++ P EP +E P
Sbjct: 777 FALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG 836
Query: 405 PRLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPA 464
P G S + E G SR S + + F E+ L + + P
Sbjct: 837 PPAPAG-----PASDTEEEEPGPEGTPPSRGSSGEGLP-FAEEGNLTI---KQRPKPAGP 887
Query: 465 SPSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEV 524
P P P ++ E +++ + +P+ R R PL L +SA+
Sbjct: 888 PPRETPVPPGLDFNLTE------SDTVKRRPKCRER----EPLQTALLAFGVASATPGPA 937
Query: 525 KYEKSAELSGEFPKEPREKQKEGHSLDGACIP 556
+ GE P Q E SL +P
Sbjct: 938 A-PLPSPTPGESPPASSLPQPEPSSLPAQGVP 968
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 51.2 bits (121), Expect = 9e-06
Identities = 102/452 (22%), Positives = 156/452 (34%), Gaps = 69/452 (15%)
Query: 120 SGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVA 179
+GEGP T+ P ++ F+ ++ P L A++ G G P
Sbjct: 653 NGEGPATAGP-------------RLLTFQGSELSPELQAAMAGG---------GPEPLPL 690
Query: 180 AKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARP--LVEPRPR 237
P+Q+ G R + SQ+ P PQ G PP + + E T RP L P
Sbjct: 691 PPARSPSQESIGARSRGSGHSQEQ--PAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPG 748
Query: 238 LKRRPVSAIFTESIQPQKPGPG-------AAATVGKVPPTPPEKTWVRKPRPLSMDLTAR 290
P ++ + P P PG A + + P TPP+ +P+ S L +R
Sbjct: 749 QGPPPYVFMYPQG-SPSSPAPGPPPGAPWAFSYLAGPPATPPDPP---RPKRRSHSL-SR 803
Query: 291 FENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKK 350
E A+ G T G A L R + R LV+ + ++
Sbjct: 804 PGPTEGDAEGEAEGPVGSTLGSYATLTR-----RPGRSALVRTSPSVTPTPARGTPRSQS 858
Query: 351 IRERKEKMLSKPEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDP------EPEKAAESPS 404
R + P + V G S P D+SP ++ P EP +E P
Sbjct: 859 FALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG 918
Query: 405 PRLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPA 464
P G S + E G SR S + + F E+ L + + P
Sbjct: 919 PPAPAG-----PASDTEEEEPGPEGTPPSRGSSGEGLP-FAEEGNLTI---KQRPKPAGP 969
Query: 465 SPSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEV 524
P P P ++ E +++ + +P+ R R PL L +SA+
Sbjct: 970 PPRETPVPPGLDFNLTE------SDTVKRRPKCRER----EPLQTALLAFGVASATPGPA 1019
Query: 525 KYEKSAELSGEFPKEPREKQKEGHSLDGACIP 556
+ GE P Q E SL +P
Sbjct: 1020 A-PLPSPTPGESPPASSLPQPEPSSLPAQGVP 1050
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 49.3 bits (116), Expect = 3e-05
Identities = 66/235 (28%), Positives = 83/235 (35%), Gaps = 40/235 (17%)
Query: 41 GAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEE 100
GAP SP PA P P+ AP P + V P P P++T P P G S
Sbjct: 984 GAPTPPAATPPSPKGGPAT--PSPKGAPTPPA----VTPPSPKGSPAAT-PFPKGA-STP 1035
Query: 101 PAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAV 160
PAA S +G ++PL A P++ L + K GPA
Sbjct: 1036 PAATP-------------PSPKGSPAATPLPKGA----PTTPAATL-PSPKGGPATPS-- 1075
Query: 161 SEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSK 220
+ G+ AA P P PA P+ AP+ PP P + G PP K
Sbjct: 1076 ----------LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP--KGGLATPPHK 1123
Query: 221 ASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKT 275
+ A P P A T + P P G A K PT P T
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178
Score = 48.9 bits (115), Expect = 4e-05
Identities = 67/269 (24%), Positives = 88/269 (32%), Gaps = 35/269 (13%)
Query: 19 LGEMGKEETLTRTYFLQAGEASGAPPARILEAKSP--LRSPARLLPLPRLAPKPFSKEQD 76
L G +++ T+ GAP + SP + P + P P + PF KE
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 77 VKSPVPSLRP--SSTGPSPSG--------GLSEEPAAKDLDNRMPGLVGQEVGSGEGPRT 126
+P P P S T SP G+ P+ K G GP T
Sbjct: 901 A-TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG---GPAT 956
Query: 127 SSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPT 186
SP + P ++T + K GPA G+ AA P P
Sbjct: 957 PSPKWAPT----PPAATP---PSPKGGPATPSP------------KGAPTPPAATPPSPK 997
Query: 187 QKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAI 246
PA P+ AP PP P+ P AS+ P + P P A
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057
Query: 247 FTESIQPQKPGPGAAATVGKVPPTPPEKT 275
T + P G A K PTPP T
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Score = 47.0 bits (110), Expect = 2e-04
Identities = 59/235 (25%), Positives = 72/235 (30%), Gaps = 42/235 (17%)
Query: 41 GAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEE 100
GAP SP PA P P+ AP P P++T PSP GGL+
Sbjct: 1078 GAPTPPAATPPSPKGGPAT--PSPKGAPMP---------------PAATPPSPKGGLATP 1120
Query: 101 PAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAV 160
P G+ P + P + P T P G A
Sbjct: 1121 P---------------HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 161 SEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSK 220
G+ AA P P A P+ AP + PP P+ G P K
Sbjct: 1166 PPP--------KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK--GGLATPSPK 1215
Query: 221 ASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKT 275
+ A P P A T + P P G A K PTPP T
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Score = 44.3 bits (103), Expect = 0.001
Identities = 117/558 (20%), Positives = 176/558 (31%), Gaps = 68/558 (12%)
Query: 41 GAPPARILEAKSPLRSPARLLPLPRLAPKPF-----SKEQDVKSPVPSLRPSS---TGPS 92
GAP SP PA P P+ AP P S + + +P P+ T PS
Sbjct: 1239 GAPTTPAATPPSPKGGPAT--PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296
Query: 93 PSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT-- 150
P GG + P K GS P AV T L TT
Sbjct: 1297 PKGGPATSPP-KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 151 -KSGPAL-----GKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTK 204
K GP G K G + + P PA+P+ K T P PLS
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 205 PPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATV 264
P P G PSK P+ + P T S + P
Sbjct: 1416 PATPVTREGA-ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 265 GKVPPTPPEKTWVRKPR-----PLSM---DLTARFENKEALLRKVADEGSGPTAGDMAGL 316
K PP P + P+ P M L A + + P A L
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534
Query: 317 ERPRAASKLDRDCLV----KAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEM-------- 364
+ A+ ++ L+ +P P + + A KE S P +
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS-SPPAVTPSTYKGA 1593
Query: 365 GSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRVADGE 424
SP+ L+ + +PS ++P A P PEK +P+P+ G S + D
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAP-TPPAVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDSP 1651
Query: 425 AAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSVQERIR 484
+ +++ +G+ P A+ P+ +KG +++E +
Sbjct: 1652 TS--------------------PASVTCKMGATVPQASKGLPA-----KKGPTALKEVLV 1686
Query: 485 GWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNEVKYEKSAELSGEFPKEPREKQ 544
ES+ R+ Q + SA + ++ N K S ++
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746
Query: 545 KEGHSLDGACIPRSPWKP 562
K D + P+ P P
Sbjct: 1747 KTAKGKDASHSPKGPLAP 1764
Score = 41.6 bits (96), Expect = 0.007
Identities = 70/292 (23%), Positives = 100/292 (34%), Gaps = 81/292 (27%)
Query: 43 PPARILEAKSPLRSPARLLPLPRLAPK-PFSKEQDVKSPVPSLRPSS------------- 88
PPA + SP ++PA +P P+ AP P SKE S P++ PS+
Sbjct: 1550 PPA--MTVPSPKKTPA--IPTPKEAPATPSSKEA---SSPPAVTPSTYKGAPSPKELLIP 1602
Query: 89 -----------------TGPSPSGG-------------------LSEEPAAKDLDNRMPG 112
T PSP G L + P + G
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662
Query: 113 LVGQEVGSGEGPRTSSPLFNKAVFLRPS-SSTMILFETTKSGPALGKAVSEGA-----EE 166
+ G P P K V + P+ ST I+ T+ GP K+ +
Sbjct: 1663 ATVPQASKGL-PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
Query: 167 AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVED 226
AK G G VA P LP QK + + S K P+ PP +S
Sbjct: 1722 AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA--------PPESKASTPL 1773
Query: 227 TARPLVEPRPRLKRRPVSAIFTESIQ-PQKPGPGAAATVGKVPPTPPEKTWV 277
TA + P+ + VSA + + P P P VP PP++ ++
Sbjct: 1774 TAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP--------VPTLPPKQQFL 1817
Score = 40.8 bits (94), Expect = 0.012
Identities = 62/232 (26%), Positives = 84/232 (36%), Gaps = 35/232 (15%)
Query: 864 PEGARSKPGVGARGPPQGCPLDPLSRATNGPSDSQARTHPDAFAVQKG-PFIVAAREGDP 922
P + PG PP+G P P A PS T P KG P +++EG
Sbjct: 1317 PPSPKGSPGTP---PPKGAPTPP---AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370
Query: 923 GPAQVPQPAVRMRKAGAMDQRMDRWRRRTLPPNVKFDTFSSLV----PEDSPHVGHRRTD 978
PA P G +R P+ K D S V P+ +P R
Sbjct: 1371 PPAATPS------HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 979 YVSPTASALRKPQLSHYRVETQEVN---------PGASRDQTSPAVKQGSPVEPKATFFA 1029
+P+ L P ++ ++ P + D T PAV SP EP A
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 1030 VTYQIPNTQKAKGVVLSGAESL---LEHSRKITP--PSS---PHSLTSTLVS 1073
T P A + GA +L + S K P PSS P + T+TL+S
Sbjct: 1485 ATSSSPKKAPATPAPM-GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 48.5 bits (114), Expect = 6e-05
Identities = 119/575 (20%), Positives = 196/575 (34%), Gaps = 87/575 (15%)
Query: 36 AGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSG 95
A +A P+++ K P+R+P L R P + V V + + TGP
Sbjct: 816 AAQAKQRSPSKV---KPPVRNPQNSTVLAR-GP---ASVPSVGKAVATAAQAQTGPEEDS 868
Query: 96 GLSEEPA-----AKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT 150
G SEE + A+ L P ++ + P SP R ++ +T
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--------RKGAAPTPPGKTG 920
Query: 151 KSGPALGKAVSEGAEEAKLGVSGSRPEV--------------------AAKPALPTQKPA 190
S GK G+ + G P A A P Q A
Sbjct: 921 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 191 GTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVE---------DTARPLVEPRPRL--- 238
+ PR A S+ T E +D P+ TA P + P+ +
Sbjct: 981 ASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA 1040
Query: 239 KRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALL 298
S+ ++ + + P + VG +P T P+ T V+ + E ++A
Sbjct: 1041 SSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK 1100
Query: 299 RKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKM 358
+ + S ++ +G E + + P L V + E E
Sbjct: 1101 APESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETL----VEETAAESSEDD 1156
Query: 359 LSKPEMGSPRALVGG--SSGVTPSNDQSPWEEKAKLDPEPE-----KAAESPSPRL-GRG 410
+ P ++L+ G + G+TP+N Q+ + KLD P A + P + +
Sbjct: 1157 VVAPS----QSLLSGYMTPGLTPANSQAS-KATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1211
Query: 411 LELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAP 470
+ A + S G+ AA G + K + + STLAL L P
Sbjct: 1212 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEA 1271
Query: 471 EPEKGVVSV--------QERIRGWTAESSEAKPEVRRRTFQA------RPLSADLTKLFS 516
+ + VV V ++++ T ESS E R+R P S KL +
Sbjct: 1272 QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGA 1331
Query: 517 SSASSNEVKYEKSAELSGEFPKEPRE----KQKEG 547
V EK++ S K + K+K+G
Sbjct: 1332 GEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG 1366
Score = 45.8 bits (107), Expect = 4e-04
Identities = 73/295 (24%), Positives = 109/295 (36%), Gaps = 57/295 (19%)
Query: 46 RILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLS----EEP 101
+IL+ ++ +PA+ P P P K V S + +P S S S E P
Sbjct: 296 KILQVRAA-SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 102 AAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVS 161
AAK L +VG+ P SP K P K+GPA+ KA +
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKESP--RKGAAPAPPG---------KTGPAVAKAQA 403
Query: 162 EGAEE----------------AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKP 205
EE A+ SG P+V A A + P + P + T P
Sbjct: 404 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP--RKTGP 461
Query: 206 PVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQP--QKPGPGAAAT 263
Q + G+ S++SS E + R ++A+ ++P + P A+T
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESDS----------DREALAAMNAAQVKPLGKSPQVKPAST 511
Query: 264 VGKVP------PTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSG--PTA 310
+G P P PP K P S + E+ E+ + +D G PTA
Sbjct: 512 MGMGPLGKGAGPVPPGKVGPATP---SAQVGKWEEDSESSSEESSDSSDGEVPTA 563
Score = 35.4 bits (80), Expect = 0.51
Identities = 105/548 (19%), Positives = 198/548 (36%), Gaps = 66/548 (12%)
Query: 1237 PVQLGGVEQRRRSLKEMPDTGGLWKPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPF 1296
P + G V + ++ K D+ + +S +E L + A + +G S+P
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK 379
Query: 1297 WALPPSAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDP 1356
+ P + P G PA + + G E+D ++ S + A++KPSG+
Sbjct: 380 ES--PRKGAAPAPPGKTGPAVAKAQAGKREEDSQS--SSEESDSEEEAPAQAKPSGKAPQ 435
Query: 1357 GSGVRVSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPA 1416
K P P + TG + Q G D R+ SE+
Sbjct: 436 VRAASAPAKESPRKGAAPAPPRKTGPAA--AQVQVGKQEED--------SRSSSEESD-- 483
Query: 1417 NIREGLSIMHEARER-RREQPKGRPSLT----------GENLEAKMGPCWWESGTGDSHK 1465
+ RE L+ M+ A+ + + P+ +P+ T G K+GP + G +
Sbjct: 484 SDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEE 543
Query: 1466 VLPRDLEKEDAPQEKERPLQQVSP---------VASVPWRSHSFCKDRRSGPFVDQLKQC 1516
E+ + E P V+P + + P S + +++GP Q+K
Sbjct: 544 DSESSSEESSDSSDGEVP-TAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK-- 600
Query: 1517 FSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLS 1576
+P D E+ +E+ + + A P T+ P + ++ S
Sbjct: 601 ----AEKPMDNSESSEESSDSAD--SEEAPAAMTAAQAKPALKIPQTKACPKKTN-TTAS 653
Query: 1577 SQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTS 1636
++ P G Q + + T+ + + G + P D S + S
Sbjct: 654 AKVAPVRVGTQ---APRKAGTATSPAGSSPAVAGGTQRPAE---------DSSSSEESDS 701
Query: 1637 VLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPL---EDETDNTWMFKDSTEE 1693
+ + L V +K + + + + S + +P+ + T + + E+
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 1694 KSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAP 1753
+EESD EE A+ + S + +PA +A K + +PG+ + A
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAK---ANPAAARAPSAK-GTISAPGKVVTAAA 817
Query: 1754 QPKSPKSP 1761
Q K +SP
Sbjct: 818 QAKQ-RSP 824
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 48.1 bits (113), Expect = 8e-05
Identities = 69/278 (24%), Positives = 92/278 (33%), Gaps = 22/278 (7%)
Query: 24 KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPS 83
KE T T AP A + + PA P P K P P+
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343
Query: 84 L--RPSSTGPS-PSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPS 140
P+ T P P+ +EPA P + S P+ +P K+ P+
Sbjct: 344 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAPTTTKSA---PT 398
Query: 141 SSTMILFETTKSGPALGKAVSEGA--EEAKLGVSGSRPEVAAKPALPTQK-PAGTLPRSA 197
++ TTKS P K S E A P KPA T K PA T P+
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE- 457
Query: 198 PLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPG 257
P TK P P + P + + T + L P K P + P+KP
Sbjct: 458 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPE-KLAPTT--------PEKPA 507
Query: 258 PGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKE 295
P + P P T +P P + A KE
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545
Score = 45.1 bits (105), Expect = 6e-04
Identities = 65/300 (21%), Positives = 100/300 (33%), Gaps = 40/300 (13%)
Query: 10 ITPLTAVPGLGEMGKEETLT--RTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLA 67
I P ++P + KE +LT + ++ E + + K S + + +
Sbjct: 124 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 183
Query: 68 PKPFSKEQDVKS-PVPSLRPSSTGPS------PSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
K + V + P P ++ GP+ P+ +EPA+
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT--------------- 228
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
P+ +P K+ P TTKS P K E A P
Sbjct: 229 ---PKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPK------EPAPTTTKEPAPTTPK 276
Query: 181 KPALPTQK-PAGTLPRSAPLSQDTKPPVPQEEAGQDHP--PSKASSVEDTARPLVEPRPR 237
+PA T K PA T +SAP + P ++ P P+ + E T EP P
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 238 LKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEA 296
K P + P+KP P P P T ++P P + A K A
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396
Score = 40.8 bits (94), Expect = 0.012
Identities = 69/289 (23%), Positives = 102/289 (35%), Gaps = 29/289 (10%)
Query: 11 TPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKP 70
TP T KE T T AP KS +P P P P
Sbjct: 217 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT----TKSAPTTPKEPAPTTTKEPAP 272
Query: 71 FSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPL 130
+ ++ + P++T +P+ +EPA + P + + P+ +P
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPT--TPKEPAPTT--PKKPAPTTPKEPAPTTPKEPTPT 328
Query: 131 FNKAVFLRPSSSTMILFETTKSGPA----LGKAVSEGAEEAKLGVSGSRPEVAAKPALPT 186
K P+ +T TT PA A + E A P +P+ T
Sbjct: 329 TPK----EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384
Query: 187 QK-PAGTLPRSAPLSQDTKPPVP---QEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRP 242
K PA T +SAP + TK P P + PS ++ E EP P ++P
Sbjct: 385 PKEPAPTTTKSAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 442
Query: 243 VSAIFTE--SIQPQKPGPGA----AATVGKVP-PTPPEKTWVRKPRPLS 284
E P++P P A T K P PT P++T P+ L+
Sbjct: 443 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Score = 38.1 bits (87), Expect = 0.078
Identities = 57/259 (22%), Positives = 91/259 (35%), Gaps = 19/259 (7%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDV----KSPVPSL--RPSSTGPS-PSGGLSEEPAA 103
K P + + P P P + ++ K P P+ +P+ T P P+ +EPA
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 104 KDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT-KSGPALGKAVSE 162
+ P + + P+ ++P K L P++ + T K P + ++
Sbjct: 461 TT--TKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPEKPAPTTPEELAP 516
Query: 163 GAEEAKLGVSGSRPEV----AAKPALPTQKPAGTLPRS-APLSQDTKPPVPQEEAGQDHP 217
E + P AA P P ++PA T P+ AP + P +E P
Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 575
Query: 218 PSKASSVEDTARPLVEPRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTW 276
A + P +P K P + S KP P P P T
Sbjct: 576 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 635
Query: 277 VRKPRPLSMDLTARFENKE 295
++P P + TA KE
Sbjct: 636 PKEPAPTTPKGTAPTTLKE 654
Score = 36.6 bits (83), Expect = 0.23
Identities = 60/266 (22%), Positives = 88/266 (33%), Gaps = 37/266 (13%)
Query: 165 EEAKLGVSGSRPEVAAKPALPTQK---------PAGTLPRS-APLSQDTKPPVPQEEAGQ 214
E A G + KPA T K PA T P+ AP + +T PP E +
Sbjct: 667 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS-- 724
Query: 215 DHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
P+ + E P L P S P++PG T T PE
Sbjct: 725 --TPTTTKEPTTIHKSPDESTPELSAEPTPKALENS--PKEPG---VPTTKTPAATKPEM 777
Query: 275 TWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAE 334
T K + DL E A + + T + + A + +
Sbjct: 778 TTTAKDKTTERDLRTTPETTTAAPKMTKETA---TTTEKTTESKITATTTQVTSTTTQDT 834
Query: 335 APLHDPDLDFLEVAKKIRERKE-----KMLSKP-EMGSPRALVGGSSGVTPSNDQSPWE- 387
P L +A K+ K+ ++++KP E P+ S TP Q P +
Sbjct: 835 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKA 893
Query: 388 -------EKAKLDPEPEKAAESPSPR 406
+K K P K +P+PR
Sbjct: 894 PKKPTSTKKPKTMPRVRKPKTTPTPR 919
Score = 36.2 bits (82), Expect = 0.30
Identities = 50/230 (21%), Positives = 73/230 (31%), Gaps = 16/230 (6%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVG 115
+P +L P P P + E+ +P P+ T P + + AA + P
Sbjct: 494 TPEKLAPTTPEKPAPTTPEE--LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTT 550
Query: 116 QEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSR 175
+ + P+ +P K T TT PA +E
Sbjct: 551 PKEPAPTTPKEPAPTTPKETAPTTPKGTA---PTTLKEPAPTTPKKPAPKELA------- 600
Query: 176 PEVAAKPALPT-QKPAGTLPR-SAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVE 233
P +P T KPA T P+ +AP + P +E P A + P
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660
Query: 234 PRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRP 282
+P K P + S KP P P P T +KP P
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710
Score = 35.4 bits (80), Expect = 0.51
Identities = 52/226 (23%), Positives = 76/226 (33%), Gaps = 21/226 (9%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAA---KDLDNRMPG 112
+P L P P P + E+ + P +T P+ +EPA K+ P
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568
Query: 113 LVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVS 172
G P T L A + L TT P K
Sbjct: 569 ETAPTTPKGTAPTT---LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 621
Query: 173 GSRPEVAAKPALPTQK-PAGTLPR-SAPLS-QDTKPPVPQEEAGQDHPPSKASSVEDTAR 229
G+ P +PA T K PA T P+ +AP + ++ P P++ A ++ P+ T
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681
Query: 230 PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKT 275
P + P + P+KP P P TPP T
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAP-------TTPETPPPTT 720
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 48.1 bits (113), Expect = 8e-05
Identities = 69/278 (24%), Positives = 92/278 (33%), Gaps = 22/278 (7%)
Query: 24 KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPS 83
KE T T AP A + + PA P P K P P+
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384
Query: 84 L--RPSSTGPS-PSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPS 140
P+ T P P+ +EPA P + S P+ +P K+ P+
Sbjct: 385 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAPTTTKSA---PT 439
Query: 141 SSTMILFETTKSGPALGKAVSEGA--EEAKLGVSGSRPEVAAKPALPTQK-PAGTLPRSA 197
++ TTKS P K S E A P KPA T K PA T P+
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE- 498
Query: 198 PLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPG 257
P TK P P + P + + T + L P K P + P+KP
Sbjct: 499 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPE-KLAPTT--------PEKPA 548
Query: 258 PGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKE 295
P + P P T +P P + A KE
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586
Score = 45.1 bits (105), Expect = 6e-04
Identities = 65/300 (21%), Positives = 100/300 (33%), Gaps = 40/300 (13%)
Query: 10 ITPLTAVPGLGEMGKEETLT--RTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLA 67
I P ++P + KE +LT + ++ E + + K S + + +
Sbjct: 165 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 224
Query: 68 PKPFSKEQDVKS-PVPSLRPSSTGPS------PSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
K + V + P P ++ GP+ P+ +EPA+
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT--------------- 269
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
P+ +P K+ P TTKS P K E A P
Sbjct: 270 ---PKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPK------EPAPTTTKEPAPTTPK 317
Query: 181 KPALPTQK-PAGTLPRSAPLSQDTKPPVPQEEAGQDHP--PSKASSVEDTARPLVEPRPR 237
+PA T K PA T +SAP + P ++ P P+ + E T EP P
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 238 LKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEA 296
K P + P+KP P P P T ++P P + A K A
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437
Score = 40.8 bits (94), Expect = 0.012
Identities = 69/289 (23%), Positives = 102/289 (35%), Gaps = 29/289 (10%)
Query: 11 TPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKP 70
TP T KE T T AP KS +P P P P
Sbjct: 258 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT----TKSAPTTPKEPAPTTTKEPAP 313
Query: 71 FSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPL 130
+ ++ + P++T +P+ +EPA + P + + P+ +P
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPT--TPKEPAPTT--PKKPAPTTPKEPAPTTPKEPTPT 369
Query: 131 FNKAVFLRPSSSTMILFETTKSGPA----LGKAVSEGAEEAKLGVSGSRPEVAAKPALPT 186
K P+ +T TT PA A + E A P +P+ T
Sbjct: 370 TPK----EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425
Query: 187 QK-PAGTLPRSAPLSQDTKPPVP---QEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRP 242
K PA T +SAP + TK P P + PS ++ E EP P ++P
Sbjct: 426 PKEPAPTTTKSAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 483
Query: 243 VSAIFTE--SIQPQKPGPGA----AATVGKVP-PTPPEKTWVRKPRPLS 284
E P++P P A T K P PT P++T P+ L+
Sbjct: 484 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Score = 38.1 bits (87), Expect = 0.078
Identities = 57/259 (22%), Positives = 91/259 (35%), Gaps = 19/259 (7%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDV----KSPVPSL--RPSSTGPS-PSGGLSEEPAA 103
K P + + P P P + ++ K P P+ +P+ T P P+ +EPA
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 104 KDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT-KSGPALGKAVSE 162
+ P + + P+ ++P K L P++ + T K P + ++
Sbjct: 502 TT--TKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPEKPAPTTPEELAP 557
Query: 163 GAEEAKLGVSGSRPEV----AAKPALPTQKPAGTLPRS-APLSQDTKPPVPQEEAGQDHP 217
E + P AA P P ++PA T P+ AP + P +E P
Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 616
Query: 218 PSKASSVEDTARPLVEPRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTW 276
A + P +P K P + S KP P P P T
Sbjct: 617 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 676
Query: 277 VRKPRPLSMDLTARFENKE 295
++P P + TA KE
Sbjct: 677 PKEPAPTTPKGTAPTTLKE 695
Score = 36.6 bits (83), Expect = 0.23
Identities = 60/266 (22%), Positives = 88/266 (33%), Gaps = 37/266 (13%)
Query: 165 EEAKLGVSGSRPEVAAKPALPTQK---------PAGTLPRS-APLSQDTKPPVPQEEAGQ 214
E A G + KPA T K PA T P+ AP + +T PP E +
Sbjct: 708 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS-- 765
Query: 215 DHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
P+ + E P L P S P++PG T T PE
Sbjct: 766 --TPTTTKEPTTIHKSPDESTPELSAEPTPKALENS--PKEPG---VPTTKTPAATKPEM 818
Query: 275 TWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAE 334
T K + DL E A + + T + + A + +
Sbjct: 819 TTTAKDKTTERDLRTTPETTTAAPKMTKETA---TTTEKTTESKITATTTQVTSTTTQDT 875
Query: 335 APLHDPDLDFLEVAKKIRERKE-----KMLSKP-EMGSPRALVGGSSGVTPSNDQSPWE- 387
P L +A K+ K+ ++++KP E P+ S TP Q P +
Sbjct: 876 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKA 934
Query: 388 -------EKAKLDPEPEKAAESPSPR 406
+K K P K +P+PR
Sbjct: 935 PKKPTSTKKPKTMPRVRKPKTTPTPR 960
Score = 36.2 bits (82), Expect = 0.30
Identities = 50/230 (21%), Positives = 73/230 (31%), Gaps = 16/230 (6%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVG 115
+P +L P P P + E+ +P P+ T P + + AA + P
Sbjct: 535 TPEKLAPTTPEKPAPTTPEE--LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTT 591
Query: 116 QEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSR 175
+ + P+ +P K T TT PA +E
Sbjct: 592 PKEPAPTTPKEPAPTTPKETAPTTPKGTA---PTTLKEPAPTTPKKPAPKELA------- 641
Query: 176 PEVAAKPALPT-QKPAGTLPR-SAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVE 233
P +P T KPA T P+ +AP + P +E P A + P
Sbjct: 642 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 701
Query: 234 PRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRP 282
+P K P + S KP P P P T +KP P
Sbjct: 702 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751
Score = 35.4 bits (80), Expect = 0.51
Identities = 52/226 (23%), Positives = 76/226 (33%), Gaps = 21/226 (9%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAA---KDLDNRMPG 112
+P L P P P + E+ + P +T P+ +EPA K+ P
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609
Query: 113 LVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVS 172
G P T L A + L TT P K
Sbjct: 610 ETAPTTPKGTAPTT---LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 662
Query: 173 GSRPEVAAKPALPTQK-PAGTLPR-SAPLS-QDTKPPVPQEEAGQDHPPSKASSVEDTAR 229
G+ P +PA T K PA T P+ +AP + ++ P P++ A ++ P+ T
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722
Query: 230 PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKT 275
P + P + P+KP P P TPP T
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAP-------TTPETPPPTT 761
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 48.1 bits (113), Expect = 8e-05
Identities = 69/278 (24%), Positives = 92/278 (33%), Gaps = 22/278 (7%)
Query: 24 KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPS 83
KE T T AP A + + PA P P K P P+
Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 84 L--RPSSTGPS-PSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPS 140
P+ T P P+ +EPA P + S P+ +P K+ P+
Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAPTTTKSA---PT 491
Query: 141 SSTMILFETTKSGPALGKAVSEGA--EEAKLGVSGSRPEVAAKPALPTQK-PAGTLPRSA 197
++ TTKS P K S E A P KPA T K PA T P+
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE- 550
Query: 198 PLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPG 257
P TK P P + P + + T + L P K P + P+KP
Sbjct: 551 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPE-KLAPTT--------PEKPA 600
Query: 258 PGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKE 295
P + P P T +P P + A KE
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638
Score = 45.1 bits (105), Expect = 6e-04
Identities = 65/300 (21%), Positives = 100/300 (33%), Gaps = 40/300 (13%)
Query: 10 ITPLTAVPGLGEMGKEETLT--RTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLA 67
I P ++P + KE +LT + ++ E + + K S + + +
Sbjct: 217 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 276
Query: 68 PKPFSKEQDVKS-PVPSLRPSSTGPS------PSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
K + V + P P ++ GP+ P+ +EPA+
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT--------------- 321
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
P+ +P K+ P TTKS P K E A P
Sbjct: 322 ---PKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPK------EPAPTTTKEPAPTTPK 369
Query: 181 KPALPTQK-PAGTLPRSAPLSQDTKPPVPQEEAGQDHP--PSKASSVEDTARPLVEPRPR 237
+PA T K PA T +SAP + P ++ P P+ + E T EP P
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429
Query: 238 LKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEA 296
K P + P+KP P P P T ++P P + A K A
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489
Score = 40.8 bits (94), Expect = 0.012
Identities = 69/289 (23%), Positives = 102/289 (35%), Gaps = 29/289 (10%)
Query: 11 TPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKP 70
TP T KE T T AP KS +P P P P
Sbjct: 310 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT----TKSAPTTPKEPAPTTTKEPAP 365
Query: 71 FSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPL 130
+ ++ + P++T +P+ +EPA + P + + P+ +P
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPT--TPKEPAPTT--PKKPAPTTPKEPAPTTPKEPTPT 421
Query: 131 FNKAVFLRPSSSTMILFETTKSGPA----LGKAVSEGAEEAKLGVSGSRPEVAAKPALPT 186
K P+ +T TT PA A + E A P +P+ T
Sbjct: 422 TPK----EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477
Query: 187 QK-PAGTLPRSAPLSQDTKPPVP---QEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRP 242
K PA T +SAP + TK P P + PS ++ E EP P ++P
Sbjct: 478 PKEPAPTTTKSAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 535
Query: 243 VSAIFTE--SIQPQKPGPGA----AATVGKVP-PTPPEKTWVRKPRPLS 284
E P++P P A T K P PT P++T P+ L+
Sbjct: 536 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Score = 38.1 bits (87), Expect = 0.078
Identities = 57/259 (22%), Positives = 91/259 (35%), Gaps = 19/259 (7%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDV----KSPVPSL--RPSSTGPS-PSGGLSEEPAA 103
K P + + P P P + ++ K P P+ +P+ T P P+ +EPA
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 104 KDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT-KSGPALGKAVSE 162
+ P + + P+ ++P K L P++ + T K P + ++
Sbjct: 554 TT--TKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPEKPAPTTPEELAP 609
Query: 163 GAEEAKLGVSGSRPEV----AAKPALPTQKPAGTLPRS-APLSQDTKPPVPQEEAGQDHP 217
E + P AA P P ++PA T P+ AP + P +E P
Sbjct: 610 TTPEEPTPTTPEEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 668
Query: 218 PSKASSVEDTARPLVEPRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTW 276
A + P +P K P + S KP P P P T
Sbjct: 669 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728
Query: 277 VRKPRPLSMDLTARFENKE 295
++P P + TA KE
Sbjct: 729 PKEPAPTTPKGTAPTTLKE 747
Score = 36.6 bits (83), Expect = 0.23
Identities = 60/266 (22%), Positives = 88/266 (33%), Gaps = 37/266 (13%)
Query: 165 EEAKLGVSGSRPEVAAKPALPTQK---------PAGTLPRS-APLSQDTKPPVPQEEAGQ 214
E A G + KPA T K PA T P+ AP + +T PP E +
Sbjct: 760 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS-- 817
Query: 215 DHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
P+ + E P L P S P++PG T T PE
Sbjct: 818 --TPTTTKEPTTIHKSPDESTPELSAEPTPKALENS--PKEPG---VPTTKTPAATKPEM 870
Query: 275 TWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAE 334
T K + DL E A + + T + + A + +
Sbjct: 871 TTTAKDKTTERDLRTTPETTTAAPKMTKETA---TTTEKTTESKITATTTQVTSTTTQDT 927
Query: 335 APLHDPDLDFLEVAKKIRERKE-----KMLSKP-EMGSPRALVGGSSGVTPSNDQSPWE- 387
P L +A K+ K+ ++++KP E P+ S TP Q P +
Sbjct: 928 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKA 986
Query: 388 -------EKAKLDPEPEKAAESPSPR 406
+K K P K +P+PR
Sbjct: 987 PKKPTSTKKPKTMPRVRKPKTTPTPR 1012
Score = 36.2 bits (82), Expect = 0.30
Identities = 50/230 (21%), Positives = 73/230 (31%), Gaps = 16/230 (6%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVG 115
+P +L P P P + E+ +P P+ T P + + AA + P
Sbjct: 587 TPEKLAPTTPEKPAPTTPEE--LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTT 643
Query: 116 QEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSR 175
+ + P+ +P K T TT PA +E
Sbjct: 644 PKEPAPTTPKEPAPTTPKETAPTTPKGTA---PTTLKEPAPTTPKKPAPKELA------- 693
Query: 176 PEVAAKPALPT-QKPAGTLPR-SAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVE 233
P +P T KPA T P+ +AP + P +E P A + P
Sbjct: 694 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 753
Query: 234 PRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRP 282
+P K P + S KP P P P T +KP P
Sbjct: 754 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Score = 35.4 bits (80), Expect = 0.51
Identities = 52/226 (23%), Positives = 76/226 (33%), Gaps = 21/226 (9%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAA---KDLDNRMPG 112
+P L P P P + E+ + P +T P+ +EPA K+ P
Sbjct: 603 TPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661
Query: 113 LVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVS 172
G P T L A + L TT P K
Sbjct: 662 ETAPTTPKGTAPTT---LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 714
Query: 173 GSRPEVAAKPALPTQK-PAGTLPR-SAPLS-QDTKPPVPQEEAGQDHPPSKASSVEDTAR 229
G+ P +PA T K PA T P+ +AP + ++ P P++ A ++ P+ T
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774
Query: 230 PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKT 275
P + P + P+KP P P TPP T
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAP-------TTPETPPPTT 813
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 48.1 bits (113), Expect = 8e-05
Identities = 69/278 (24%), Positives = 92/278 (33%), Gaps = 22/278 (7%)
Query: 24 KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPS 83
KE T T AP A + + PA P P K P P+
Sbjct: 418 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 84 L--RPSSTGPS-PSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPS 140
P+ T P P+ +EPA P + S P+ +P K+ P+
Sbjct: 478 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAPTTTKSA---PT 532
Query: 141 SSTMILFETTKSGPALGKAVSEGA--EEAKLGVSGSRPEVAAKPALPTQK-PAGTLPRSA 197
++ TTKS P K S E A P KPA T K PA T P+
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE- 591
Query: 198 PLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPG 257
P TK P P + P + + T + L P K P + P+KP
Sbjct: 592 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPE-KLAPTT--------PEKPA 641
Query: 258 PGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKE 295
P + P P T +P P + A KE
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679
Score = 45.1 bits (105), Expect = 6e-04
Identities = 65/300 (21%), Positives = 100/300 (33%), Gaps = 40/300 (13%)
Query: 10 ITPLTAVPGLGEMGKEETLT--RTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLA 67
I P ++P + KE +LT + ++ E + + K S + + +
Sbjct: 258 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 317
Query: 68 PKPFSKEQDVKS-PVPSLRPSSTGPS------PSGGLSEEPAAKDLDNRMPGLVGQEVGS 120
K + V + P P ++ GP+ P+ +EPA+
Sbjct: 318 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT--------------- 362
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
P+ +P K+ P TTKS P K E A P
Sbjct: 363 ---PKEPTPTTIKSAPTTPKEPAPT---TTKSAPTTPK------EPAPTTTKEPAPTTPK 410
Query: 181 KPALPTQK-PAGTLPRSAPLSQDTKPPVPQEEAGQDHP--PSKASSVEDTARPLVEPRPR 237
+PA T K PA T +SAP + P ++ P P+ + E T EP P
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470
Query: 238 LKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEA 296
K P + P+KP P P P T ++P P + A K A
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530
Score = 40.8 bits (94), Expect = 0.012
Identities = 69/289 (23%), Positives = 102/289 (35%), Gaps = 29/289 (10%)
Query: 11 TPLTAVPGLGEMGKEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRLAPKP 70
TP T KE T T AP KS +P P P P
Sbjct: 351 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT----TKSAPTTPKEPAPTTTKEPAP 406
Query: 71 FSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPL 130
+ ++ + P++T +P+ +EPA + P + + P+ +P
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPT--TPKEPAPTT--PKKPAPTTPKEPAPTTPKEPTPT 462
Query: 131 FNKAVFLRPSSSTMILFETTKSGPA----LGKAVSEGAEEAKLGVSGSRPEVAAKPALPT 186
K P+ +T TT PA A + E A P +P+ T
Sbjct: 463 TPK----EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518
Query: 187 QK-PAGTLPRSAPLSQDTKPPVP---QEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRP 242
K PA T +SAP + TK P P + PS ++ E EP P ++P
Sbjct: 519 PKEPAPTTTKSAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 576
Query: 243 VSAIFTE--SIQPQKPGPGA----AATVGKVP-PTPPEKTWVRKPRPLS 284
E P++P P A T K P PT P++T P+ L+
Sbjct: 577 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Score = 38.1 bits (87), Expect = 0.078
Identities = 57/259 (22%), Positives = 91/259 (35%), Gaps = 19/259 (7%)
Query: 51 KSPLRSPARLLPLPRLAPKPFSKEQDV----KSPVPSL--RPSSTGPS-PSGGLSEEPAA 103
K P + + P P P + ++ K P P+ +P+ T P P+ +EPA
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 104 KDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT-KSGPALGKAVSE 162
+ P + + P+ ++P K L P++ + T K P + ++
Sbjct: 595 TT--TKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPEKPAPTTPEELAP 650
Query: 163 GAEEAKLGVSGSRPEV----AAKPALPTQKPAGTLPRS-APLSQDTKPPVPQEEAGQDHP 217
E + P AA P P ++PA T P+ AP + P +E P
Sbjct: 651 TTPEEPTPTTPEEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 709
Query: 218 PSKASSVEDTARPLVEPRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTW 276
A + P +P K P + S KP P P P T
Sbjct: 710 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769
Query: 277 VRKPRPLSMDLTARFENKE 295
++P P + TA KE
Sbjct: 770 PKEPAPTTPKGTAPTTLKE 788
Score = 36.6 bits (83), Expect = 0.23
Identities = 60/266 (22%), Positives = 88/266 (33%), Gaps = 37/266 (13%)
Query: 165 EEAKLGVSGSRPEVAAKPALPTQK---------PAGTLPRS-APLSQDTKPPVPQEEAGQ 214
E A G + KPA T K PA T P+ AP + +T PP E +
Sbjct: 801 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS-- 858
Query: 215 DHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEK 274
P+ + E P L P S P++PG T T PE
Sbjct: 859 --TPTTTKEPTTIHKSPDESTPELSAEPTPKALENS--PKEPG---VPTTKTPAATKPEM 911
Query: 275 TWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAE 334
T K + DL E A + + T + + A + +
Sbjct: 912 TTTAKDKTTERDLRTTPETTTAAPKMTKETA---TTTEKTTESKITATTTQVTSTTTQDT 968
Query: 335 APLHDPDLDFLEVAKKIRERKE-----KMLSKP-EMGSPRALVGGSSGVTPSNDQSPWE- 387
P L +A K+ K+ ++++KP E P+ S TP Q P +
Sbjct: 969 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPTKA 1027
Query: 388 -------EKAKLDPEPEKAAESPSPR 406
+K K P K +P+PR
Sbjct: 1028 PKKPTSTKKPKTMPRVRKPKTTPTPR 1053
Score = 36.2 bits (82), Expect = 0.30
Identities = 50/230 (21%), Positives = 73/230 (31%), Gaps = 16/230 (6%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVG 115
+P +L P P P + E+ +P P+ T P + + AA + P
Sbjct: 628 TPEKLAPTTPEKPAPTTPEE--LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTT 684
Query: 116 QEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSR 175
+ + P+ +P K T TT PA +E
Sbjct: 685 PKEPAPTTPKEPAPTTPKETAPTTPKGTA---PTTLKEPAPTTPKKPAPKELA------- 734
Query: 176 PEVAAKPALPT-QKPAGTLPR-SAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVE 233
P +P T KPA T P+ +AP + P +E P A + P
Sbjct: 735 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 794
Query: 234 PRPRLKR-RPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRP 282
+P K P + S KP P P P T +KP P
Sbjct: 795 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Score = 35.4 bits (80), Expect = 0.51
Identities = 52/226 (23%), Positives = 76/226 (33%), Gaps = 21/226 (9%)
Query: 56 SPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAA---KDLDNRMPG 112
+P L P P P + E+ + P +T P+ +EPA K+ P
Sbjct: 644 TPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702
Query: 113 LVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVS 172
G P T L A + L TT P K
Sbjct: 703 ETAPTTPKGTAPTT---LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 755
Query: 173 GSRPEVAAKPALPTQK-PAGTLPR-SAPLS-QDTKPPVPQEEAGQDHPPSKASSVEDTAR 229
G+ P +PA T K PA T P+ +AP + ++ P P++ A ++ P+ T
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815
Query: 230 PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKT 275
P + P + P+KP P P TPP T
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAP-------TTPETPPPTT 854
>gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]
Length = 878
Score = 48.1 bits (113), Expect = 8e-05
Identities = 76/342 (22%), Positives = 122/342 (35%), Gaps = 87/342 (25%)
Query: 176 PEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTARPLVEPR 235
P+ PA P +P G PP P+ + PSKA TA L PR
Sbjct: 425 PQCLPPPATPRLEPRG-------------PPAPEVVKQPVYLPSKAGPKAQTA-CLPPPR 470
Query: 236 PRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRK-PRPLSMDLTARFENK 294
P +RPV+ QP + A T ++PP P++ K P + ++ + +
Sbjct: 471 P---QRPVTKARRPPPQPHR----RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVD- 522
Query: 295 EALLRKVADEGSGPTAGDMAGLERPRAASKL------------------------DRDCL 330
+ +E GP+ G E+ R K+ +D +
Sbjct: 523 ------IMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFV 576
Query: 331 VKAEAPLH----------DPDLDFLEVAKKIRERKEKMLSK-PEMGSPRALVGGSSGVTP 379
K EA +H DP +DFL +++ + + + L++ E P S P
Sbjct: 577 TKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAP 636
Query: 380 SNDQSPWEEKAKLDPEPEKAA-------ESPSPRLGRGLELAEVKSRVADGEAAAGGEWA 432
S A+LD K A + P P+ G G+E ++ D +
Sbjct: 637 SRG------TARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTG 690
Query: 433 SRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEK 474
RS EDS + L +SP A P++ P+ +
Sbjct: 691 MARS---------EDSVVLLGC-QDSPGLRAARPTSPPQDHR 722
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 48.1 bits (113), Expect = 8e-05
Identities = 124/584 (21%), Positives = 201/584 (34%), Gaps = 104/584 (17%)
Query: 36 AGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSG 95
A +A P+++ K P+R+P L R P + V V + + TGP
Sbjct: 816 AAQAKQRSPSKV---KPPVRNPQNSTVLAR-GP---ASVPSVGKAVATAAQAQTGPEEDS 868
Query: 96 GLSEEPA-----AKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT 150
G SEE + A+ L P ++ + P SP R ++ +T
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--------RKGAAPTPPGKTG 920
Query: 151 KSGPALGKAVSEGAEEAKLGVSGSRPEV--------------------AAKPALPTQKPA 190
S GK G+ + G P A A P Q A
Sbjct: 921 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 980
Query: 191 GTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVE---------DTARPLVEPRPRL--- 238
+ PR A S+ T E +D P+ TA P + P+ +
Sbjct: 981 ASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA 1040
Query: 239 KRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWV--------RKPR-PLSMDLTA 289
S+ ++ + + P + VG +P T P+ T V RKP+ P T
Sbjct: 1041 SSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK 1100
Query: 290 RFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAK 349
E+ + +++ S ++G E P+ A K+ L P E
Sbjct: 1101 APESSDD-----SEDSSDSSSGSEEDGEGPQGA---------KSAHTLVGPTPSRTETL- 1145
Query: 350 KIRERKEKMLSKPEMGSPRALVGG--SSGVTPSNDQSPWEEKAKLDPEPE-----KAAES 402
+ E + + ++L+ G + G+TP+N Q+ + KLD P A +
Sbjct: 1146 -VEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQAS-KATPKLDSSPSVSSTLAAKDD 1203
Query: 403 PSPRL-GRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLA 461
P + + + A + S G+ AA G + K + + STLAL L
Sbjct: 1204 PDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLL 1263
Query: 462 TPASPSAAPEPEKGVVSV--------QERIRGWTAESSEAKPEVRRRTFQA------RPL 507
P + + VV V ++++ T ESS E R+R P
Sbjct: 1264 GQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPR 1323
Query: 508 SADLTKLFSSSASSNEVKYEKSAELSGEFPKEPRE----KQKEG 547
S KL + V EK++ S K + K+K+G
Sbjct: 1324 SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG 1367
Score = 45.8 bits (107), Expect = 4e-04
Identities = 73/295 (24%), Positives = 109/295 (36%), Gaps = 57/295 (19%)
Query: 46 RILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLS----EEP 101
+IL+ ++ +PA+ P P P K V S + +P S S S E P
Sbjct: 296 KILQVRAA-SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 102 AAKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVS 161
AAK L +VG+ P SP K P K+GPA+ KA +
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKESP--RKGAAPAPPG---------KTGPAVAKAQA 403
Query: 162 EGAEE----------------AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKP 205
EE A+ SG P+V A A + P + P + T P
Sbjct: 404 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP--RKTGP 461
Query: 206 PVPQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTESIQP--QKPGPGAAAT 263
Q + G+ S++SS E + R ++A+ ++P + P A+T
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESDS----------DREALAAMNAAQVKPLGKSPQVKPAST 511
Query: 264 VGKVP------PTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSG--PTA 310
+G P P PP K P S + E+ E+ + +D G PTA
Sbjct: 512 MGMGPLGKGAGPVPPGKVGPATP---SAQVGKWEEDSESSSEESSDSSDGEVPTA 563
Score = 35.4 bits (80), Expect = 0.51
Identities = 105/548 (19%), Positives = 198/548 (36%), Gaps = 66/548 (12%)
Query: 1237 PVQLGGVEQRRRSLKEMPDTGGLWKPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPF 1296
P + G V + ++ K D+ + +S +E L + A + +G S+P
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK 379
Query: 1297 WALPPSAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDP 1356
+ P + P G PA + + G E+D ++ S + A++KPSG+
Sbjct: 380 ES--PRKGAAPAPPGKTGPAVAKAQAGKREEDSQS--SSEESDSEEEAPAQAKPSGKAPQ 435
Query: 1357 GSGVRVSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPA 1416
K P P + TG + Q G D R+ SE+
Sbjct: 436 VRAASAPAKESPRKGAAPAPPRKTGPAA--AQVQVGKQEED--------SRSSSEESD-- 483
Query: 1417 NIREGLSIMHEARER-RREQPKGRPSLT----------GENLEAKMGPCWWESGTGDSHK 1465
+ RE L+ M+ A+ + + P+ +P+ T G K+GP + G +
Sbjct: 484 SDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEE 543
Query: 1466 VLPRDLEKEDAPQEKERPLQQVSP---------VASVPWRSHSFCKDRRSGPFVDQLKQC 1516
E+ + E P V+P + + P S + +++GP Q+K
Sbjct: 544 DSESSSEESSDSSDGEVP-TAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK-- 600
Query: 1517 FSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLS 1576
+P D E+ +E+ + + A P T+ P + ++ S
Sbjct: 601 ----AEKPMDNSESSEESSDSAD--SEEAPAAMTAAQAKPALKIPQTKACPKKTN-TTAS 653
Query: 1577 SQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTS 1636
++ P G Q + + T+ + + G + P D S + S
Sbjct: 654 AKVAPVRVGTQ---APRKAGTATSPAGSSPAVAGGTQRPAE---------DSSSSEESDS 701
Query: 1637 VLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPL---EDETDNTWMFKDSTEE 1693
+ + L V +K + + + + S + +P+ + T + + E+
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 1694 KSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAP 1753
+EESD EE A+ + S + +PA +A K + +PG+ + A
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAK---ANPAAARAPSAK-GTISAPGKVVTAAA 817
Query: 1754 QPKSPKSP 1761
Q K +SP
Sbjct: 818 QAKQ-RSP 824
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 47.4 bits (111), Expect = 1e-04
Identities = 82/339 (24%), Positives = 125/339 (36%), Gaps = 61/339 (17%)
Query: 6 EVGSITPLTAV--PGLGEMGKEETLTRTYFLQAGEASGAPPA--RILEAKSPLRSPARLL 61
E GS+ A PG+ G+ ++ + + E A +IL+ ++ +PA+
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAA-SAPAKGT 233
Query: 62 PLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLS----EEPAAKDLDNRMPGLVGQE 117
P P P K V S + +P S S S E PAAK L +
Sbjct: 234 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 293
Query: 118 VGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEE----------- 166
VG+ P SP K P K+GPA+ KA + EE
Sbjct: 294 VGAASAPAKESP--RKGAAPAPPG---------KTGPAVAKAQAGKREEDSQSSSEESDS 342
Query: 167 -----AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKA 221
A+ SG P+V A A + P + P + T P Q + G+ S++
Sbjct: 343 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP--RKTGPAAAQVQVGKQEEDSRS 400
Query: 222 SSVEDTARPLVEPRPRLKRRPVSAIFTESIQP--QKPGPGAAATVGKVP------PTPPE 273
SS E + R ++A+ ++P + P A+T+G P P PP
Sbjct: 401 SSEESDS----------DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG 450
Query: 274 KTWVRKPRPLSMDLTARFENKEALLRKVADEGSG--PTA 310
K P S + E+ E+ + +D G PTA
Sbjct: 451 KVGPATP---SAQVGKWEEDSESSSEESSDSSDGEVPTA 486
Score = 42.0 bits (97), Expect = 0.005
Identities = 128/622 (20%), Positives = 205/622 (32%), Gaps = 142/622 (22%)
Query: 36 AGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSG 95
A +A P+++ K P+R+P L R P + V V + + TGP
Sbjct: 739 AAQAKQRSPSKV---KPPVRNPQNSTVLAR-GP---ASVPSVGKAVATAAQAQTGPEEDS 791
Query: 96 GLSEEPA-----AKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT 150
G SEE + A+ L P ++ + P SP R ++ +T
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--------RKGAAPTPPGKTG 843
Query: 151 KSGPALGKAVSEGAEEAKLGVSGSRPEV--------------------AAKPALPTQKPA 190
S GK G+ + G P A A P Q A
Sbjct: 844 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 903
Query: 191 GTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVE---------DTARPLVEPRPRL--- 238
+ PR A S+ T E +D P+ TA P + P+ +
Sbjct: 904 ASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA 963
Query: 239 -----------------------KRRPVSAIFTES---------------IQPQKPGPGA 260
K+ P S T++ + +P G
Sbjct: 964 SSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV 1023
Query: 261 AATVGKVPPTPPEKTWV--------RKPR-PLSMDLTARFENKEALLRKVADEGSGPTAG 311
+ VG +P T P+ T V RKP+ P T E+ + +++ S ++G
Sbjct: 1024 DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD-----SEDSSDSSSG 1078
Query: 312 DMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEMGSPRALV 371
E P+ A K+ L P E + E + + ++L+
Sbjct: 1079 SEEDGEGPQGA---------KSAHTLVGPTPSRTETL--VEETAAESSEDDVVAPSQSLL 1127
Query: 372 GG--SSGVTPSNDQSPWEEKAKLDPEPE-----KAAESPSPRL-GRGLELAEVKSRVADG 423
G + G+TP+N Q+ + KLD P A + P + + + A + S G
Sbjct: 1128 SGYMTPGLTPANSQAS-KATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1186
Query: 424 EAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSV---- 479
+ AA G + K + + STLAL L P + + VV V
Sbjct: 1187 KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL 1246
Query: 480 ----QERIRGWTAESSEAKPEVRRRTFQA------RPLSADLTKLFSSSASSNEVKYEKS 529
++++ T ESS E R+R P S KL + V EK+
Sbjct: 1247 LEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKT 1306
Query: 530 AELSGEFPKEPRE----KQKEG 547
+ S K + K+K+G
Sbjct: 1307 STTSKGKAKRDKASGDVKEKKG 1328
Score = 37.0 bits (84), Expect = 0.17
Identities = 112/603 (18%), Positives = 218/603 (36%), Gaps = 71/603 (11%)
Query: 1187 PGKIRDGYRSSVLDIDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRER-----PVQLG 1241
PG + G S + + ++ ++ +K + + R+ + P + P + G
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 247
Query: 1242 GVEQRRRSLKEMPDTGGLWKPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPP 1301
V + ++ K D+ + +S +E L + A + +G S+P + P
Sbjct: 248 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES--P 305
Query: 1302 SAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVR 1361
+ P G PA + + G E+D ++ S + A++KPSG+
Sbjct: 306 RKGAAPAPPGKTGPAVAKAQAGKREEDSQS--SSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 1362 VSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREG 1421
K P P + TG + Q G D R+ SE+ + RE
Sbjct: 364 APAKESPRKGAAPAPPRKTGPAA--AQVQVGKQEED--------SRSSSEESD--SDREA 411
Query: 1422 LSIMHEARER-RREQPKGRPSLT----------GENLEAKMGPCWWESGTGDSHKVLPRD 1470
L+ M+ A+ + + P+ +P+ T G K+GP + G +
Sbjct: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 471
Query: 1471 LEKEDAPQEKERPLQQVSP---------VASVPWRSHSFCKDRRSGPFVDQLKQCFSRQP 1521
E+ + E P V+P + + P S + +++GP Q+K
Sbjct: 472 SEESSDSSDGEVP-TAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK------A 524
Query: 1522 TEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSSQTEP 1581
+P D E+ +E+ + + A P T+ P + ++ S++ P
Sbjct: 525 EKPMDNSESSEESSDSAD--SEEAPAAMTAAQAKPALKIPQTKACPKKTN-TTASAKVAP 581
Query: 1582 TSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLDSS 1641
G Q + + T+ + + G + P D S + S + +
Sbjct: 582 VRVGTQ---APRKAGTATSPAGSSPAVAGGTQRPAE---------DSSSSEESDSEEEKT 629
Query: 1642 ALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPL---EDETDNTWMFKDSTEEKSPRK 1698
L V +K + + + + S + +P+ + T + + E+ +
Sbjct: 630 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 689
Query: 1699 EESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAPQPKSP 1758
EESD EE A+ + S + +PA +A K + +PG+ + A Q K
Sbjct: 690 EESDSEEAAASPAQVKTSVKKTQAK---ANPAAARAPSAK-GTISAPGKVVTAAAQAKQ- 744
Query: 1759 KSP 1761
+SP
Sbjct: 745 RSP 747
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 47.4 bits (111), Expect = 1e-04
Identities = 82/339 (24%), Positives = 125/339 (36%), Gaps = 61/339 (17%)
Query: 6 EVGSITPLTAV--PGLGEMGKEETLTRTYFLQAGEASGAPPA--RILEAKSPLRSPARLL 61
E GS+ A PG+ G+ ++ + + E A +IL+ ++ +PA+
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAA-SAPAKGT 233
Query: 62 PLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLS----EEPAAKDLDNRMPGLVGQE 117
P P P K V S + +P S S S E PAAK L +
Sbjct: 234 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 293
Query: 118 VGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEE----------- 166
VG+ P SP K P K+GPA+ KA + EE
Sbjct: 294 VGAASAPAKESP--RKGAAPAPPG---------KTGPAVAKAQAGKREEDSQSSSEESDS 342
Query: 167 -----AKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKA 221
A+ SG P+V A A + P + P + T P Q + G+ S++
Sbjct: 343 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP--RKTGPAAAQVQVGKQEEDSRS 400
Query: 222 SSVEDTARPLVEPRPRLKRRPVSAIFTESIQP--QKPGPGAAATVGKVP------PTPPE 273
SS E + R ++A+ ++P + P A+T+G P P PP
Sbjct: 401 SSEESDS----------DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG 450
Query: 274 KTWVRKPRPLSMDLTARFENKEALLRKVADEGSG--PTA 310
K P S + E+ E+ + +D G PTA
Sbjct: 451 KVGPATP---SAQVGKWEEDSESSSEESSDSSDGEVPTA 486
Score = 42.4 bits (98), Expect = 0.004
Identities = 123/613 (20%), Positives = 200/613 (32%), Gaps = 125/613 (20%)
Query: 36 AGEASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSG 95
A +A P+++ K P+R+P L R P + V V + + TGP
Sbjct: 739 AAQAKQRSPSKV---KPPVRNPQNSTVLAR-GP---ASVPSVGKAVATAAQAQTGPEEDS 791
Query: 96 GLSEEPA-----AKDLDNRMPGLVGQEVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETT 150
G SEE + A+ L P ++ + P SP R ++ +T
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--------RKGAAPTPPGKTG 843
Query: 151 KSGPALGKAVSEGAEEAKLGVSGSRPEV--------------------AAKPALPTQKPA 190
S GK G+ + G P A A P Q A
Sbjct: 844 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQA 903
Query: 191 GTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVE---------DTARPLVEPRPRL--- 238
+ PR A S+ T E +D P+ TA P + P+ +
Sbjct: 904 ASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA 963
Query: 239 -----------------------KRRPVSAIFTES---------------IQPQKPGPGA 260
K+ P S T++ + +P G
Sbjct: 964 SSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV 1023
Query: 261 AATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEALLRKVADEGSGPTAGDMAGLERPR 320
+ VG +P T P+ T V+ + E ++A + + S ++ +G E
Sbjct: 1024 DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG 1083
Query: 321 AASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSKPEMGSPRALVGG--SSGVT 378
+ + P L V + E E + P ++L+ G + G+T
Sbjct: 1084 EGPQGAKSAHTLGPTPSRTETL----VEETAAESSEDDVVAPS----QSLLSGYMTPGLT 1135
Query: 379 PSNDQSPWEEKAKLDPEPE-----KAAESPSPRL-GRGLELAEVKSRVADGEAAAGGEWA 432
P+N Q+ + KLD P A + P + + + A + S G+ AA G
Sbjct: 1136 PANSQAS-KATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTP 1194
Query: 433 SRRSVRKCISLFREDSTLALAVGSESPLATPASPSAAPEPEKGVVSV--------QERIR 484
+ K + + STLAL L P + + VV V ++++
Sbjct: 1195 QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVV 1254
Query: 485 GWTAESSEAKPEVRRRTFQA------RPLSADLTKLFSSSASSNEVKYEKSAELSGEFPK 538
T ESS E R+R P S KL + V EK++ S K
Sbjct: 1255 DTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAK 1314
Query: 539 EPRE----KQKEG 547
+ K+K+G
Sbjct: 1315 RDKASGDVKEKKG 1327
Score = 37.0 bits (84), Expect = 0.17
Identities = 112/603 (18%), Positives = 218/603 (36%), Gaps = 71/603 (11%)
Query: 1187 PGKIRDGYRSSVLDIDALMAEYQELSLKVPGEAQERRSPTVEPSTLPRER-----PVQLG 1241
PG + G S + + ++ ++ +K + + R+ + P + P + G
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 247
Query: 1242 GVEQRRRSLKEMPDTGGLWKPASSAEINHSFTPGLGKQLAETLETAMGTKSSPPFWALPP 1301
V + ++ K D+ + +S +E L + A + +G S+P + P
Sbjct: 248 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKES--P 305
Query: 1302 SAPSERYPGGSPIPADPRKKTGFAEDDRKAFASKHHVAKCQNYLAESKPSGREDPGSGVR 1361
+ P G PA + + G E+D ++ S + A++KPSG+
Sbjct: 306 RKGAAPAPPGKTGPAVAKAQAGKREEDSQS--SSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 1362 VSPKSPPTDQKKGTPRKSTGRGEEDSVAQWGDHPRDCGRVPLDIKRAYSEKGPPANIREG 1421
K P P + TG + Q G D R+ SE+ + RE
Sbjct: 364 APAKESPRKGAAPAPPRKTGPAA--AQVQVGKQEED--------SRSSSEESD--SDREA 411
Query: 1422 LSIMHEARER-RREQPKGRPSLT----------GENLEAKMGPCWWESGTGDSHKVLPRD 1470
L+ M+ A+ + + P+ +P+ T G K+GP + G +
Sbjct: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 471
Query: 1471 LEKEDAPQEKERPLQQVSP---------VASVPWRSHSFCKDRRSGPFVDQLKQCFSRQP 1521
E+ + E P V+P + + P S + +++GP Q+K
Sbjct: 472 SEESSDSSDGEVP-TAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK------A 524
Query: 1522 TEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSSQTEP 1581
+P D E+ +E+ + + A P T+ P + ++ S++ P
Sbjct: 525 EKPMDNSESSEESSDSAD--SEEAPAAMTAAQAKPALKIPQTKACPKKTN-TTASAKVAP 581
Query: 1582 TSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLDSS 1641
G Q + + T+ + + G + P D S + S + +
Sbjct: 582 VRVGTQ---APRKAGTATSPAGSSPAVAGGTQRPAE---------DSSSSEESDSEEEKT 629
Query: 1642 ALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPL---EDETDNTWMFKDSTEEKSPRK 1698
L V +K + + + + S + +P+ + T + + E+ +
Sbjct: 630 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 689
Query: 1699 EESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAPQPKSP 1758
EESD EE A+ + S + +PA +A K + +PG+ + A Q K
Sbjct: 690 EESDSEEAAASPAQVKTSVKKTQAK---ANPAAARAPSAK-GTISAPGKVVTAAAQAKQ- 744
Query: 1759 KSP 1761
+SP
Sbjct: 745 RSP 747
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/195 (25%), Positives = 69/195 (35%), Gaps = 25/195 (12%)
Query: 39 ASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLS 98
A APP + SPL P P +P+PF +P PS+ S P G
Sbjct: 425 AQSAPPEAAVLPPSPL-------PAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 477
Query: 99 EEPAAKDLDNR--MPGLVGQEVG----------SGEGPRTSSPLFNKAVFLRPSSSTMIL 146
+ P + R P +G S +GP T P F V PS + +
Sbjct: 478 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGP-TPLPSFTSGV---PSHAPVSG 533
Query: 147 FETT--KSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTK 204
+T SGP + ++ G PE A P+ ++ SAPL +
Sbjct: 534 SPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 593
Query: 205 PPVPQEEAGQDHPPS 219
P P G PPS
Sbjct: 594 PEAPAPGPGAPEPPS 608
Score = 33.9 bits (76), Expect = 1.5
Identities = 54/255 (21%), Positives = 90/255 (35%), Gaps = 33/255 (12%)
Query: 1540 TWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRS--- 1596
T+T++ + + ES + K + S L++ P S G R QR+
Sbjct: 249 TYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKY 308
Query: 1597 TSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQTSVLDSSALKTR---VQLSKRS 1653
T V + + +G PP E +D+ +F D S+ + S + ++L++
Sbjct: 309 TLVSFGAAAGTGAEEEDGVPPTS---ESELDEEAFSDARSLTNQSDWDSPYLDMELARAG 365
Query: 1654 RRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDSTEEKSPRKEESDEEETASKAERT 1713
R + S + SE R +F+ + +E E A+
Sbjct: 366 SRASEGQGSGLGGQLSEVSGRG--------VQLFEQQRQRADSSTQELARVEPAAMLNGE 417
Query: 1714 PVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLP 1773
+ P R + P + AVL PS P P + PFQPG P
Sbjct: 418 GLQSPPRAQSAPP-EAAVLP---------------PSPLPAPVASPRPFQPGGGAPTPAP 461
Query: 1774 SSMDKDERSDEPSPQ 1788
S ++ R P Q
Sbjct: 462 SIFNRSARPFTPGLQ 476
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/195 (25%), Positives = 69/195 (35%), Gaps = 25/195 (12%)
Query: 39 ASGAPPARILEAKSPLRSPARLLPLPRLAPKPFSKEQDVKSPVPSLRPSSTGPSPSGGLS 98
A APP + SPL P P +P+PF +P PS+ S P G
Sbjct: 201 AQSAPPEAAVLPPSPL-------PAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 253
Query: 99 EEPAAKDLDNR--MPGLVGQEVG----------SGEGPRTSSPLFNKAVFLRPSSSTMIL 146
+ P + R P +G S +GP T P F V PS + +
Sbjct: 254 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGP-TPLPSFTSGV---PSHAPVSG 309
Query: 147 FETT--KSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLPRSAPLSQDTK 204
+T SGP + ++ G PE A P+ ++ SAPL +
Sbjct: 310 SPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 369
Query: 205 PPVPQEEAGQDHPPS 219
P P G PPS
Sbjct: 370 PEAPAPGPGAPEPPS 384
Score = 32.7 bits (73), Expect = 3.3
Identities = 59/277 (21%), Positives = 96/277 (34%), Gaps = 38/277 (13%)
Query: 1518 SRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESLATESPDSSATSTRKQPPSSRLSSLSS 1577
S++P D ++ + Q ESL +S + T R + S L++
Sbjct: 8 SQEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCR-----TIASLLTA 62
Query: 1578 QTEPTSAGDQYDCSRDQRS---TSVDHSSTDLESTDGMEGPPPPDACPEKRVDDFSFIDQ 1634
P S G R QR+ T V + + +G PP E +D+ +F D
Sbjct: 63 APNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTS---ESELDEEAFSDA 119
Query: 1635 TSVLDSSALKTR---VQLSKRSRRRAPISHSLRRSRFSESESRSPLEDETDNTWMFKDST 1691
S+ + S + ++L++ R + S + SE R +F+
Sbjct: 120 RSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRG--------VQLFEQQR 171
Query: 1692 EEKSPRKEESDEEETASKAERTPVSHPQRMPAFPGMDPAVLKAQLHKRPEVDSPGETPSW 1751
+ +E E A+ + P R + P + AVL PS
Sbjct: 172 QRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPP-EAAVLP---------------PSP 215
Query: 1752 APQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQ 1788
P P + PFQPG PS ++ R P Q
Sbjct: 216 LPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQ 252
>gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
Length = 333
Score = 47.0 bits (110), Expect = 2e-04
Identities = 76/274 (27%), Positives = 105/274 (38%), Gaps = 63/274 (22%)
Query: 66 LAPKPFSKEQDVK---SPVPSLR--------PSSTGPSPSG------GLSEEPAAKDLD- 107
L+P +E+D+ +P LR P++ P+P G LS E + LD
Sbjct: 21 LSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDE 80
Query: 108 -NRMPGLVGQ-------EVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKS------- 152
NR+ + Q G G GPR P + F+ S L T S
Sbjct: 81 ANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPS 140
Query: 153 ----GPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQK--PAGTLPRSAPLSQDTKPP 206
P L +G+ A SG RP K PT PA P S+PL++ T PP
Sbjct: 141 PSSLTPRLRSNDRKGSVRALRATSGKRPS-NMKRESPTCNLFPASKSPASSPLTRST-PP 198
Query: 207 VPQEEAGQDHPPSKASSVEDT-ARPLVEPRP------RLKRRPVSAIFTESIQP-----Q 254
V G+ P +A++ T R ++ P+P RL R +A + S P
Sbjct: 199 V----RGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIP 254
Query: 255 KPGPGAAATVGKVPP----TPPEKTWVRK--PRP 282
+P T VPP PP+ RK PRP
Sbjct: 255 RPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRP 288
Score = 32.3 bits (72), Expect = 4.3
Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 17/185 (9%)
Query: 8 GSITPLTAVPGLGEMG-KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRL 66
GS+ L A G K E+ T F + + +P R + P+R A P R
Sbjct: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR---STPPVRGRAG--PSGRA 209
Query: 67 APKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMP------GLVGQEVGS 120
A P + + V +P PS S P P G ++ + + + +P L + V
Sbjct: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
G G L + RPS++ + E+ P VS+ +G + S +
Sbjct: 270 GRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP-----VSQRLNLPVMGATRSNLQPPR 324
Query: 181 KPALP 185
K A+P
Sbjct: 325 KVAVP 329
>gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
Length = 333
Score = 47.0 bits (110), Expect = 2e-04
Identities = 76/274 (27%), Positives = 105/274 (38%), Gaps = 63/274 (22%)
Query: 66 LAPKPFSKEQDVK---SPVPSLR--------PSSTGPSPSG------GLSEEPAAKDLD- 107
L+P +E+D+ +P LR P++ P+P G LS E + LD
Sbjct: 21 LSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDE 80
Query: 108 -NRMPGLVGQ-------EVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKS------- 152
NR+ + Q G G GPR P + F+ S L T S
Sbjct: 81 ANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPS 140
Query: 153 ----GPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQK--PAGTLPRSAPLSQDTKPP 206
P L +G+ A SG RP K PT PA P S+PL++ T PP
Sbjct: 141 PSSLTPRLRSNDRKGSVRALRATSGKRPS-NMKRESPTCNLFPASKSPASSPLTRST-PP 198
Query: 207 VPQEEAGQDHPPSKASSVEDT-ARPLVEPRP------RLKRRPVSAIFTESIQP-----Q 254
V G+ P +A++ T R ++ P+P RL R +A + S P
Sbjct: 199 V----RGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIP 254
Query: 255 KPGPGAAATVGKVPP----TPPEKTWVRK--PRP 282
+P T VPP PP+ RK PRP
Sbjct: 255 RPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRP 288
Score = 32.3 bits (72), Expect = 4.3
Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 17/185 (9%)
Query: 8 GSITPLTAVPGLGEMG-KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRL 66
GS+ L A G K E+ T F + + +P R + P+R A P R
Sbjct: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR---STPPVRGRAG--PSGRA 209
Query: 67 APKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMP------GLVGQEVGS 120
A P + + V +P PS S P P G ++ + + + +P L + V
Sbjct: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
Query: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180
G G L + RPS++ + E+ P VS+ +G + S +
Sbjct: 270 GRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP-----VSQRLNLPVMGATRSNLQPPR 324
Query: 181 KPALP 185
K A+P
Sbjct: 325 KVAVP 329
>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 46.6 bits (109), Expect = 2e-04
Identities = 59/211 (27%), Positives = 83/211 (39%), Gaps = 25/211 (11%)
Query: 84 LRPSSTG-PSPSGGLSEEPAAKD--LDN------RMPGLVGQEVGSGEGPRTSSPLFNKA 134
LRP + P SGG + A + LDN R+PGL G G P S A
Sbjct: 228 LRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAG-----GVEPPGWSRERAGA 282
Query: 135 VFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAG-TL 193
R S + +SG + + E A L + P A+ A + P G T
Sbjct: 283 GLSRDSP------QVPRSG-SWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATE 335
Query: 194 PRSAPLSQDTKPPV---PQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTES 250
P L+ ++ P+ P E D + A + D PRPR +RPVS +F
Sbjct: 336 PGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVK 395
Query: 251 IQPQKPGPGAAATVGKVPPTPPEKTWVRKPR 281
+ GPG++A VP T + +PR
Sbjct: 396 FFVPQSGPGSSACEVAVPTTAGRELLGSEPR 426
>gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 46.6 bits (109), Expect = 2e-04
Identities = 59/211 (27%), Positives = 83/211 (39%), Gaps = 25/211 (11%)
Query: 84 LRPSSTG-PSPSGGLSEEPAAKD--LDN------RMPGLVGQEVGSGEGPRTSSPLFNKA 134
LRP + P SGG + A + LDN R+PGL G G P S A
Sbjct: 228 LRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAG-----GVEPPGWSRERAGA 282
Query: 135 VFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAG-TL 193
R S + +SG + + E A L + P A+ A + P G T
Sbjct: 283 GLSRDSP------QVPRSG-SWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATE 335
Query: 194 PRSAPLSQDTKPPV---PQEEAGQDHPPSKASSVEDTARPLVEPRPRLKRRPVSAIFTES 250
P L+ ++ P+ P E D + A + D PRPR +RPVS +F
Sbjct: 336 PGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVK 395
Query: 251 IQPQKPGPGAAATVGKVPPTPPEKTWVRKPR 281
+ GPG++A VP T + +PR
Sbjct: 396 FFVPQSGPGSSACEVAVPTTAGRELLGSEPR 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,033,994
Number of Sequences: 37866
Number of extensions: 5189285
Number of successful extensions: 25414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 838
Number of HSP's that attempted gapping in prelim test: 20396
Number of HSP's gapped (non-prelim): 5484
length of query: 1806
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1689
effective length of database: 13,817,196
effective search space: 23337244044
effective search space used: 23337244044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.