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Search of human proteins with 222537750
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
(1392 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 2766 0.0
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 1606 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 469 e-132
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 335 1e-91
gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens] 332 1e-90
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 328 3e-89
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 322 2e-87
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 317 5e-86
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 315 2e-85
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 314 3e-85
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 314 3e-85
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 312 1e-84
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 305 2e-82
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 293 6e-79
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 293 6e-79
gi|239744894 PREDICTED: similar to Putative ankyrin repeat domai... 275 2e-73
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 274 5e-73
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 273 6e-73
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 272 1e-72
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 270 9e-72
gi|239756223 PREDICTED: ankyrin repeat domain-containing protein... 268 4e-71
gi|239745040 PREDICTED: ankyrin repeat domain-containing protein... 268 4e-71
gi|169209369 PREDICTED: similar to Putative ankyrin repeat domai... 266 8e-71
gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens] 241 5e-63
gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens] 239 1e-62
gi|169194585 PREDICTED: similar to hCG1793014 [Homo sapiens] 236 9e-62
gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens] 236 9e-62
gi|169192125 PREDICTED: similar to UNCoordinated family member (... 231 5e-60
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 230 8e-60
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 225 3e-58
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 2766 bits (7169), Expect = 0.0
Identities = 1392/1392 (100%), Positives = 1392/1392 (100%)
Query: 1 MKRLLAAAGKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVG 60
MKRLLAAAGKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVG
Sbjct: 1 MKRLLAAAGKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVG 60
Query: 61 KKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREA 120
KKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREA
Sbjct: 61 KKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREA 120
Query: 121 CANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAI 180
CANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAI
Sbjct: 121 CANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAI 180
Query: 181 QKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGIT 240
QKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGIT
Sbjct: 181 QKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGIT 240
Query: 241 AERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLE 300
AERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLE
Sbjct: 241 AERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLE 300
Query: 301 KTPDEAARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRK 360
KTPDEAARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRK
Sbjct: 301 KTPDEAARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRK 360
Query: 361 ITWEEKETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSL 420
ITWEEKETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSL
Sbjct: 361 ITWEEKETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSL 420
Query: 421 FGTRTIENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSE 480
FGTRTIENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSE
Sbjct: 421 FGTRTIENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSE 480
Query: 481 SKREEDEEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQK 540
SKREEDEEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQK
Sbjct: 481 SKREEDEEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQK 540
Query: 541 TVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEF 600
TVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEF
Sbjct: 541 TVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEF 600
Query: 601 DTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVS 660
DTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVS
Sbjct: 601 DTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVS 660
Query: 661 LPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQ 720
LPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQ
Sbjct: 661 LPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQ 720
Query: 721 KDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL 780
KDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL
Sbjct: 721 KDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL 780
Query: 781 PNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQ 840
PNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQ
Sbjct: 781 PNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQ 840
Query: 841 QERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIK 900
QERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIK
Sbjct: 841 QERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIK 900
Query: 901 TTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR 960
TTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR
Sbjct: 901 TTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR 960
Query: 961 ELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEE 1020
ELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEE
Sbjct: 961 ELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEE 1020
Query: 1021 EKRRNVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDL 1080
EKRRNVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDL
Sbjct: 1021 EKRRNVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDL 1080
Query: 1081 FHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKR 1140
FHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKR
Sbjct: 1081 FHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKR 1140
Query: 1141 ASQYREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQE 1200
ASQYREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQE
Sbjct: 1141 ASQYREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQE 1200
Query: 1201 LAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALV 1260
LAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALV
Sbjct: 1201 LAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALV 1260
Query: 1261 SEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYA 1320
SEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYA
Sbjct: 1261 SEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYA 1320
Query: 1321 HKKVNKSKVTINIQFPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYK 1380
HKKVNKSKVTINIQFPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYK
Sbjct: 1321 HKKVNKSKVTINIQFPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYK 1380
Query: 1381 YFSNFLKESGLG 1392
YFSNFLKESGLG
Sbjct: 1381 YFSNFLKESGLG 1392
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 1606 bits (4159), Expect = 0.0
Identities = 903/1434 (62%), Positives = 1004/1434 (70%), Gaps = 208/1434 (14%)
Query: 57 MTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQC 116
MT KK +NLN +D +KRTALHWACVNGH EVVTFLVDRKCQL+VLDGE RTPLMKALQC
Sbjct: 1 MTKRKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQC 60
Query: 117 EREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPL 176
+EACANILID+GAD+N VDVYGNTALHYAVYSE L +VA LLS+GAVIEV NKASLTPL
Sbjct: 61 HQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPL 120
Query: 177 LLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDI 236
LL+I KRS+Q VEFLL KNANANA N+ KCTALMLA+C GSSEIVGMLLQQNVDVFA DI
Sbjct: 121 LLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADI 180
Query: 237 HGITAERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAE 296
G+TAE YA CG ++IH+Q++E+IRKL KN QNTNPEGTS GTPDEAAPLAERTPDTAE
Sbjct: 181 CGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAE 240
Query: 297 SLLEKTPDEAA----------------------RLVEGTSAKIQCLGKATSGKFEQSTEE 334
SL+EKTPDEAA LVEGTS KIQCL KATSGKFEQS EE
Sbjct: 241 SLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEE 300
Query: 335 TPRKILRPTKETSEKFSWPAKERSRKITWEEKE-TSVKTECVAGVTPNKTEVLEKGTSNM 393
TPR+I P KETSEKF+WPAK R RKI WE+KE T + A T K KG
Sbjct: 301 TPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRK 360
Query: 394 IACPTKETSTKASTNVDVSSVEPIFSLFGTRTIENSQCTKVEEDFNLATKIISKSAAQNY 453
IA KET K V+S + TK++ K ++
Sbjct: 361 IAWEKKETPVKTGCVARVTSNK--------------------------TKVLEKGRSKMI 394
Query: 454 TCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESSAKTQVCIPESMYQ 513
C T + K DQ FPSESK+EEDEEYS DS SLFESSAK QVCIPES+YQ
Sbjct: 395 AC---PTKESSTKA---SANDQRFPSESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQ 448
Query: 514 KVMEINREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQKDDEEN 573
KVMEINREVEE P+KPSAFKPA+EMQ +VPNKAFELKNEQTLRA MFP ESKQKD EEN
Sbjct: 449 KVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYEEN 508
Query: 574 SWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALE 633
SWDSES CETVSQKDV LPKATHQKE D ++GKLEESP
Sbjct: 509 SWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESP---------------------- 546
Query: 634 LKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKV 693
+KDGLLK TCG KVS+P KALELKD +T KAE P +P +
Sbjct: 547 ------------NKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQK 594
Query: 694 SLPNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLPKATHQKEF 753
S+PNKALELK+ +T +A ++ PSESKQKD EENSWD ES ET+ Q DVCLPKA HQKE
Sbjct: 595 SVPNKALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEI 654
Query: 754 DTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTT 813
D ++GKLE SP KDGLLK CGMK+S+P KALEL D +TFKAE S F +P
Sbjct: 655 DKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEK-PSAF----EPAI 709
Query: 814 ENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKST 873
E +S K + + E+ + E P SE +K+ +S+
Sbjct: 710 EMQKSVP-------------NKALELKNEQTLRADEILP---------SESKQKDYEESS 747
Query: 874 SDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESP----------------------- 910
DSE + + +Q CLP+AT+QKEI NGK+EESP
Sbjct: 748 WDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALEL 807
Query: 911 -----------EKPSHFEPATEMQNSVPNKGLEWKNKQTLRAD----------------- 942
EKPS FEPA EMQ SVPNK LE KN+QTLRAD
Sbjct: 808 MDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFPSESKQKKVEENSW 867
Query: 943 ----------------------------------STTLSKILDALPSCERGRELKKDNCE 968
ST+LSKILD + SCER REL+KD+CE
Sbjct: 868 DSESLRETVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCE 927
Query: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028
Q T KMEQ K KFCVL+K+LSEAKEIKSQLENQK KWEQELCSVRLTLNQEEEKRRN DI
Sbjct: 928 QRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADI 987
Query: 1029 LKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083
L EKIR E EQ RK+LEVKQQLEQ LRIQDIELKSV SNLNQVSHTHE+EN L HE
Sbjct: 988 LNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHE 1047
Query: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143
NCMLKKEIAMLKLE+ATLKHQ+Q KENKYFEDIKIL+EKNAELQMTLKLK++++TKRASQ
Sbjct: 1048 NCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQ 1107
Query: 1144 YREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAF 1203
Y QLKVL AENTMLTSKLKEKQDKEILE EIESHHPRLASA+QDHDQ VTSRK+QE AF
Sbjct: 1108 YSGQLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAF 1167
Query: 1204 HSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEH 1263
H AGDA LQ MNVDVS+TIYNNEVLHQPL EAQRKSKS KINLNYAGD LREN LVSEH
Sbjct: 1168 HIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEH 1227
Query: 1264 AQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKK 1323
AQRD+ ETQCQMK+AEHMYQNEQDNV+KHTEQQESL+QKLFQL+SKN WL+QQLV+AHKK
Sbjct: 1228 AQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKK 1287
Query: 1324 V-NKSKVTINIQFPEMKMQRH-LNEKNEEVFNYGNHLKERIDQYEKEKAEREVS 1375
NKSK+TI+I F E KMQ H L EKNEE+FNY NHLK RI QYEKEKAE E S
Sbjct: 1288 ADNKSKITIDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAETENS 1341
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 469 bits (1207), Expect = e-132
Identities = 415/1295 (32%), Positives = 604/1295 (46%), Gaps = 240/1295 (18%)
Query: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248
+ LL + N ++ TAL LA G E+V +L+ + + D TA A C
Sbjct: 64 QILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQC 123
Query: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTST---GTPDEAAPLAERTPDTAESLLEKTPDE 305
LLEH +P + G + +E +A + ++ K D+
Sbjct: 124 QEEKCATILLEH----GADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDD 179
Query: 306 AARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEE 365
L+ A SGK +Q E +K + +K E S ++ E
Sbjct: 180 LTPLL-----------LAVSGKKQQMVEFLIKK--KANVNAVDKL-----ESSHQLISEY 221
Query: 366 KETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRT 425
KE + S++ S +VD SS + + L G
Sbjct: 222 KEERIPKH----------------------------SSQNSNSVDESSEDSLSRLSGKPG 253
Query: 426 IENSQCTKVEEDFNLATKIISK-------SAAQNYTCLPDATYQKDIKTINHKIEDQMFP 478
+++S T +ED N TK + K +A+Q +ATY ++T N + +
Sbjct: 254 VDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGT-VRTGNRTLFED--- 309
Query: 479 SESKREEDEEYSWDSGSLFESSAKTQVCIPESMYQ----------KVMEINREVEELPEK 528
R+ D + SL +S K Q C YQ K + ++E P K
Sbjct: 310 ----RDSDSQDEVVVESLPTTSIKVQ-CFSHPTYQSPDLLPKPSHKSLANPGLMKEEPTK 364
Query: 529 PSAFKP--AVEMQKTVP-------NKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSES 579
P K +++ ++ P N + + + R+ M Q++D E+ WDSES
Sbjct: 365 PGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWDSES 424
Query: 580 PCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRET 639
E QK V D L+G + G++ ++ N+ E
Sbjct: 425 ISENFPQKYV-----------DPLAGAAD-------------GKEKNIGNEQAE------ 454
Query: 640 FKAESPDKDGLLKPTCGRKVSLPNKALELKDRETL-----KAESPDNDGLLKPTCGRKVS 694
D P+C S K +L+D + ESP+ LKPT K S
Sbjct: 455 --------DVFYIPSC-MSGSRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDS 505
Query: 695 LPNKALELKDRETFKAAQ-----MFPSESKQKDDEENSWDFESFLETLLQNDVCLPKATH 749
+PNKA +KD +T KAA+ E +++ E N E + N++ + H
Sbjct: 506 VPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEEERKKHRNNEMEVSANIH 565
Query: 750 QKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFG 809
D + E+ D DGL++ K+ E ++ + E+ S +L
Sbjct: 566 ----DGATDDAEDDDDDDGLIQK---------RKSGETDHQQFPRKENKEYASSGPAL-- 610
Query: 810 KPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKED 869
+ K E T+KE V G+ G + + D + + GR
Sbjct: 611 -----QMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGRP-- 663
Query: 870 TKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNK 929
TK TS+ + + Q+ + + + T E + + ++ S K +
Sbjct: 664 TKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYK--------NFMLLIEQL 715
Query: 930 GLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELS 989
G+E K DS +L KI DA SCER ELKK++CE +T K+++ ++K VLQ+ELS
Sbjct: 716 GMECK-------DSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELS 768
Query: 990 EAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKI-----RPEEQLRKKLE 1044
E KEIKSQLE+QK +WE+ELCS+R +LNQEEEKRRN D L EKI R EEQ RK++E
Sbjct: 769 ETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVE 828
Query: 1045 VKQQLEQTLRIQDIELKSVTSNLNQV---------------------------------- 1070
VKQQLE +L+ ++EL++V SNLNQV
Sbjct: 829 VKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKE 888
Query: 1071 ------------SHTHESENDLFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKI 1118
SH+HE E DL H+N ML++EIAML+LE+ T+K+Q+Q KE K FED+KI
Sbjct: 889 IEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKI 948
Query: 1119 LQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLK-EKQDKEILETEIES 1177
++EKN +LQ T+K ++T+T+ SQY +L VLTAEN ML SKL+ EKQ KE LE E+ES
Sbjct: 949 VKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1008
Query: 1178 HHPRLASALQDHDQSVTSRKNQELAFHSAGD--APLQGIMNVDVSNTIYNNEVLHQPLYE 1235
+H RLA+A+ D DQS TS++ ELAF A D + LQ MN DVSN NNE+L Q L++
Sbjct: 1009 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFK 1068
Query: 1236 AQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQ 1295
+ K S +I ++ D LRE L E Q+D +TQCQMK+ E YQNEQ V+K+ +
Sbjct: 1069 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGK 1128
Query: 1296 QESLEQKLFQLESKNRWLRQQLVYAHKKV-NKSKVTINI-----------QFPEMKMQRH 1343
QES+E++L QL+S+N LRQQL AH K NK K INI Q K
Sbjct: 1129 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1188
Query: 1344 LNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKK 1378
L E+N+E+ + NHLKER QYE EKAEREV +++
Sbjct: 1189 LEERNKELISECNHLKERQYQYENEKAEREVVVRQ 1223
Score = 259 bits (661), Expect = 2e-68
Identities = 356/1517 (23%), Positives = 595/1517 (39%), Gaps = 272/1517 (17%)
Query: 2 KRLLAAAGKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGK 61
+R ++AG G G +S+ Y +D DLGKIH AAS G V K++++ + +
Sbjct: 18 RRQRSSAGGG--GEPGEGAYSQPGYHVRDR------DLGKIHKAASAGNVAKVQQILLLR 69
Query: 62 KPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREAC 121
K LN RD RTALH AC NGH EVVT LVDRKCQLNV D E RT LMKA+QC+ E C
Sbjct: 70 KN-GLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKC 128
Query: 122 ANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQ 181
A IL++ GAD N DV+GNTALHYAVY+E++ + LL Y A IE +NK LTPLLLA+
Sbjct: 129 ATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVS 188
Query: 182 KRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQN---VDVFAEDIHG 238
+ +Q VEFL+ K AN NA ++ + + + I E E + QN VD +ED
Sbjct: 189 GKKQQMVEFLIKKKANVNAVDKLESSHQL--ISEYKEERIPKHSSQNSNSVDESSED--- 243
Query: 239 ITAERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESL 298
+ R + GV+ + T ++ + P + +
Sbjct: 244 -SLSRLSGKPGVD----------------------DSWPTSDDEDLNFDTKNVPKPSLAK 280
Query: 299 LEKTPDEAARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERS 358
L ++ + +E T ++ G T FE ++ +++ + T
Sbjct: 281 LMTASQQSRKNLEATYGTVR-TGNRT--LFEDRDSDSQDEVVVESLPT------------ 325
Query: 359 RKITWEEKETSVKTECVAGVTPNKTEVLEKGTSNMIACP--TKETSTKASTNVDVSSVEP 416
TS+K +C + T ++L K + +A P KE TK + ++
Sbjct: 326 ---------TSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEEPTKPGIAKKENGID- 375
Query: 417 IFSLFGTRTIENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQM 476
I +SA T + TY ++ N D M
Sbjct: 376 ----------------------------IIESAPLEQTNNDNLTYVDEVHKNNR--SDMM 405
Query: 477 FPSESKREEDEEYSWDSGSLFESSAKTQV---------------------------CIPE 509
+EED E WDS S+ E+ + V C+
Sbjct: 406 SALGLGQEEDIESPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSG 465
Query: 510 SMYQKV--MEINREV------EELPEKPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQM- 560
S K+ +E R V E PE+ KP +EM+ +VPNKA +K+ QT +AA+
Sbjct: 466 SRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHD 525
Query: 561 FPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPT 620
S+++ + E S +++ E +K D + E+ DGL++
Sbjct: 526 LEVASEEEQEREGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKR 585
Query: 621 CGRKV---SLPNK----------ALELKD-RETFKAESPDKDGLLKPTCGRKVSLPNKAL 666
+ P K AL++K+ + T K + K+ + P G+ L L
Sbjct: 586 KSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLL 645
Query: 667 ELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEEN 726
++ D +L D K T K + N+ + D + + SE+ +D E
Sbjct: 646 QVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQS----SETASEDCELP 701
Query: 727 SWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLK-----PTCGMKISLP 781
+++F+ + Q + E D LLK +C + L
Sbjct: 702 HSSYKNFMLLIEQLGM-------------------ECKDSVSLLKIQDAALSCERLLELK 742
Query: 782 NKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEED-------FNLTTKEGAT 834
EL + K ED +V K + KVE + F+L +E
Sbjct: 743 KNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKR 802
Query: 835 KTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEAT 894
+ E+ + R + ++ + + E + T + E+ +V N
Sbjct: 803 RNADTLYEKIREQLRRKEEQYRKEVEVKQ--QLELSLQTLEMELRTVKSNLNQVVQERND 860
Query: 895 YQKEIK-------TTNGKIEESPEKPSHFEPATEMQNS------VPNKGLEWKNKQTLRA 941
Q+++ +G + K E A + NS K L KN L+
Sbjct: 861 AQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSM-LQE 919
Query: 942 DSTTLSKILDALPSCERGRELK-------------------KDNCEQITAKMEQTKNKFC 982
+ L +D + + + +E K K N E +T + Q +
Sbjct: 920 EIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLS 979
Query: 983 VLQKE-------LSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRP 1035
VL E L K+ K +LE + + L + +Q E +R +++ ++ R
Sbjct: 980 VLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD 1039
Query: 1036 E-EQLRKKLEVK-QQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCM----LKK 1089
E +L+ K+ L+ I +L S LN + D E + ++K
Sbjct: 1040 ECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQK 1099
Query: 1090 EIAMLKLEVATLKHQH---QVKENKYFEDIKILQEKNAELQMTLKL-------------- 1132
+++ + ++ ++ ++ QVK NKY + ++E+ ++LQ L
Sbjct: 1100 DLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADN 1159
Query: 1133 KQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQS 1192
K+KTV Q+ ++ L AE+ S L E+++KE++ E +H + +++++
Sbjct: 1160 KEKTVINIQDQFHAIVQKLQAESEK-QSLLLEERNKELIS---ECNHLKERQYQYENEKA 1215
Query: 1193 VTSRKNQELAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGD 1252
++L A Q + + T L + ++K + L A D
Sbjct: 1216 EREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQD 1275
Query: 1253 DLRENALVSEHAQ-------RDRCETQC----QMKKAEHMYQN---------EQDNVDKH 1292
E +E Q +D + + QM K E + +N E++ + K
Sbjct: 1276 RHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKL 1335
Query: 1293 TEQQESLEQKLFQLESKNRWLRQQLVYAHKKVNKSKVTIN-IQFPEMKMQRHLNEKNEEV 1351
E ++SLE L Q KN L +++ + ++ +N + E L E+
Sbjct: 1336 MELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEM 1395
Query: 1352 FNYGNHLKERIDQYEKE 1368
N LK +ID E
Sbjct: 1396 DIQINKLKHKIDDLTAE 1412
Score = 60.8 bits (146), Expect = 9e-09
Identities = 154/765 (20%), Positives = 299/765 (39%), Gaps = 98/765 (12%)
Query: 509 ESMYQKVMEINREVEELPEKPSAFK-PAVEMQKTVPNKAFELKNEQTLR--AAQMFPSES 565
+ M KV + RE+ E E S + VE ++ + + F L E+ R A ++
Sbjct: 754 KKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIR 813
Query: 566 KQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEE---------------- 609
+Q +E + E E Q ++ L T + E T+ L +
Sbjct: 814 EQLRRKEEQYRKE--VEVKQQLELSLQ--TLEMELRTVKSNLNQVVQERNDAQRQLSREQ 869
Query: 610 --SPVKDGLLKPTCGRK--VSLPNKALELKDRETFKAESP--DKDGLLKPTCGR------ 657
++DG+L ++ + + K + ++ + + E K+ +L+
Sbjct: 870 NARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEID 929
Query: 658 KVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSE 717
+ N+ E K E LK N+ L K + +L + R + A+
Sbjct: 930 TIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLN 989
Query: 718 SKQKDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGK-----LEESPDKDGLLKP 772
SK ++++++ E+ +E+ L A H ++ S + + + D+ L+
Sbjct: 990 SKLENEKQSKERLEAEVESYHSR---LAAAIHDRDQSETSKRELELAFQRARDECSRLQD 1046
Query: 773 TCGMKISLPNKALELKDRETFKAED-VSSVESTFSLFGKPTTENSQST-KVEEDFNLT-- 828
+S E+ ++ FK E ++S+E F E + +V++D + T
Sbjct: 1047 KMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQC 1106
Query: 829 ----------TKEGATKTVTGQQERDIGIIERAPQDQT-NKMPTSELGRKEDTKSTSDSE 877
++ G+QE + ER Q Q+ N + +L + +
Sbjct: 1107 QMKEMEQKYQNEQVKVNKYIGKQE---SVEERLSQLQSENMLLRQQLDDAHNKADNKEKT 1163
Query: 878 IISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEW---- 933
+I++ D + + + + K + E + E S E Q N+ E
Sbjct: 1164 VINIQD--QFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVV 1221
Query: 934 KNKQTLRADSTTLSKILDA-LPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAK 992
+ Q AD+ + +A L R R +D + + K+ Q +N+ Q +EA
Sbjct: 1222 RQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAV 1281
Query: 993 EIKSQLENQKAKWEQELCSVRLTLNQE----EEKRRNVDILKEKIRPEEQLRKKLEVKQQ 1048
++++ K K E++ +++T+ ++ EE ++N+ +EQL+K +E+KQ
Sbjct: 1282 RCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQS 1341
Query: 1049 LEQTL---RIQDIEL-KSVTSNLNQVSHT----HESENDLFHENCMLKKEIAMLKLEVAT 1100
LE L +++EL + +T N + T +E EN F + LK + +++
Sbjct: 1342 LECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINK 1401
Query: 1101 LKHQHQ---VKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTM 1157
LKH+ + L KN LQ L L KTV K+ + ++
Sbjct: 1402 LKHKIDDLTAELETAGSKCLHLDTKNQILQEEL-LSMKTVQKKCEKLQK----------- 1449
Query: 1158 LTSKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202
+K K +Q+ L + IE + L Q + Q + R QE+A
Sbjct: 1450 --NKKKLEQEVINLRSHIERNMVELGQVKQ-YKQEIEERARQEIA 1491
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 335 bits (860), Expect = 1e-91
Identities = 234/655 (35%), Positives = 348/655 (53%), Gaps = 90/655 (13%)
Query: 788 KDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEED---FNLTTKEGATKTVTGQQERD 844
+D + FK E V+++E F K + + + E + N T G T D
Sbjct: 497 QDMQKFKNE-VNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
Query: 845 IGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNG 904
G+ ++ P+ + E R D S +E+ + + PEA + ++ +
Sbjct: 556 DGLNQQIPRKENG-----EHDRPADKTSNEKNEVKN-------QIYPEADFADSMEPSEI 603
Query: 905 KIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKK 964
E+ S +E + +E+K DS +L +I D CE +LK
Sbjct: 604 ASEDCELSHSVYE---NFMLLIEQLRMEYK-------DSASLPRIQDTFCLCEHLLKLKN 653
Query: 965 DNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRR 1024
++C+Q+T K++Q +N VLQ ELSE K+ K QLE QK +WE+EL +RL L QE E++R
Sbjct: 654 NHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKR 713
Query: 1025 NVDIL----KEKIR-PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLN----------- 1068
N D+L E++R EE+ K +E KQQL+ LR EL++V +NL+
Sbjct: 714 NADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQK 773
Query: 1069 --------------------------------QVSHTHESENDLFHENCMLKKEIAMLKL 1096
++SH H+ E DLFHE+CML++EIA+L+L
Sbjct: 774 QLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRL 833
Query: 1097 EVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENT 1156
E+ T+K+Q++ KE KYFEDI+ ++EKN LQ +KL ++T+T+ QY QL LTAEN
Sbjct: 834 EIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENK 893
Query: 1157 MLTSKLKE-KQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD--APLQG 1213
+L S+L+ KQ++E LE E+ES+ RLA+A++D DQS T+R + +L F L
Sbjct: 894 ILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTAR-DLKLDFQRTRQEWVRLHD 952
Query: 1214 IMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQC 1273
M VD+S NE+L + L A+ K S +I L+ D L +L+ E QRD +TQC
Sbjct: 953 KMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQC 1012
Query: 1274 QMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVNKSKVTI-- 1331
Q K+ E MYQ EQ + K+ +QES+E++L QL+S+N LRQQL AHKK N + T
Sbjct: 1013 QKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSST 1072
Query: 1332 ----------NIQFPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSI 1376
N+Q K L EKN+E+ + NHLKER+DQ EKEKA R++ +
Sbjct: 1073 IQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDL 1127
Score = 38.5 bits (88), Expect = 0.045
Identities = 127/643 (19%), Positives = 240/643 (37%), Gaps = 108/643 (16%)
Query: 829 TKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSEL-GRKEDTKSTSDSEIISVSDTQNY 887
TKE +T +++ D G++ + D + + S+L KE ++ DSE+ S + +
Sbjct: 178 TKELGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDSELTSEEEQERL 237
Query: 888 E-C---LPEATYQKEIKTTNGKIEESPEKP--SHFEPATEMQNSVPNKGLEWKN--KQTL 939
+ C P+ T Q+ + E+ P P H + + EM + LEWKN K +
Sbjct: 238 KGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMW--IEQGKLEWKNQLKLVI 295
Query: 940 RADSTTLSKILD--ALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQ 997
+I + +P+C L DN + T + K+I
Sbjct: 296 NELKQRFGEIYEKYKIPACPEEEPL-LDNSTRGT------------------DVKDIPFN 336
Query: 998 LENQKAKWEQELCS-VRLTLNQEEEKRRNVDILKEKIRP-EEQLRKKLEVKQQLEQTLRI 1055
L N E+E S + +++ E + LK I P E Q +
Sbjct: 337 LTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKFHL 396
Query: 1056 QDIELKSVTSNLNQVSHTHESENDLFHENCMLKK----EIAMLKL------EVATLKHQH 1105
+ +L N + H ++ + FH + KK E+ M+++ ++ K+ +
Sbjct: 397 HENKLDCDNDNKPGIGHIFSTDKN-FHNDASTKKARNPEVVMVEMKEDQEFDLQMTKNMN 455
Query: 1106 QVKENKYFEDIKILQEKNAELQMTLKLKQKT----VTKRASQYREQLK--VLTAENTMLT 1159
Q ++ + K L+ K L +T + + Q ++ K V T E L
Sbjct: 456 QNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLA 515
Query: 1160 SKLKEKQDKEILETEIESHH---------------------------PRLASALQDHDQS 1192
K ++ Q + +E E+E H PR + D
Sbjct: 516 LKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENGEHDRPAD 575
Query: 1193 VTSRKNQELAFHSAGDAPLQGIM--------NVDVSNTIYNNEVL--HQPLYEAQRKSKS 1242
TS + E+ +A M + ++S+++Y N +L Q E + +
Sbjct: 576 KTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASL 635
Query: 1243 PKINLNYAGDDLRENALVSEHAQRDRCETQC-QMKKAEHMYQNEQDNVDKHTEQQE---- 1297
P+I + L E+ L ++ D+ + QM+ + QNE K Q E
Sbjct: 636 PRIQDTFC---LCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKI 692
Query: 1298 SLEQKLFQLESKNRWLRQQLVYAHKKVNKSKVTINIQFPE--------MKMQRHLNEKNE 1349
E++L+ L + ++ A NK + I+ E +++ +L +
Sbjct: 693 EWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVK 752
Query: 1350 EVFNYGNHL----KERIDQYEKEKAEREVSIKKYKYFSNFLKE 1388
E+ N+L +ER D ++ E++ I + + ++ KE
Sbjct: 753 ELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKE 795
Score = 37.0 bits (84), Expect = 0.13
Identities = 73/396 (18%), Positives = 154/396 (38%), Gaps = 25/396 (6%)
Query: 968 EQITAKMEQTKNKFCVLQKELSEAKEIKSQ----LENQKAKWEQELCSVRLTLNQEEEKR 1023
E ++ K+ ++K LQ +L ++ + LE + Q C + T E+ +
Sbjct: 966 EILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKET---EQMYQ 1022
Query: 1024 RNVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFH- 1082
LK+ I +E + ++L Q LR Q L N T + D FH
Sbjct: 1023 IEQSKLKKYIAKQESVEERLSQLQSENMLLRQQ---LDDAHKKANSQEKTSSTIQDQFHS 1079
Query: 1083 --ENCMLKKEIAMLKLEVATLKHQHQVKE-NKYFEDIKILQEKNAELQMTLKLKQKTVTK 1139
+N + E +L L+ K++ + E N E + +++ A ++ L Q+TV
Sbjct: 1080 AAKNLQAESEKQILSLQE---KNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPS 1136
Query: 1140 RASQYREQLKVLTAENTMLTSKLKEKQDKEILET--EIESHHPRLASALQDHDQSVTSRK 1197
R + +VL + T+ + K +KQ + + + +++ L S ++ + +
Sbjct: 1137 RCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAE 1196
Query: 1198 NQELAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQR-KSKSPKINLNYAGDDLRE 1256
+L ++ +N + V H+ L + + + S K + DL
Sbjct: 1197 WHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLES 1256
Query: 1257 NALVSEHAQRDRCETQCQMKKAEHM-----YQNEQDNVDKHTEQQESLEQKLFQLESKNR 1311
+ +Q D +T+ + K ++ ++ + + + E + +L + + R
Sbjct: 1257 EISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTR 1316
Query: 1312 WLRQQLVYAHKKVNKSKVTINIQFPEMKMQRHLNEK 1347
YA + V +S N+ E ++H+ K
Sbjct: 1317 SRSLFTAYATRPVLESPCVGNLNDSEGLNRKHIPRK 1352
>gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 251
Score = 332 bits (852), Expect = 1e-90
Identities = 173/251 (68%), Positives = 200/251 (79%), Gaps = 1/251 (0%)
Query: 1 MKRLLAAAGKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVG 60
M+RL AAA KG G E P+PFS+ VYT D I+ GDL KIH AASRGQ KLE+M +
Sbjct: 1 MERLSAAAVKGQTGLECPSPFSQLVYTNNDSYVIHHGDLRKIHKAASRGQAWKLERM-MK 59
Query: 61 KKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREA 120
K ++LN RD KKRTALHWAC NG AEVVT LVDRKCQL++LDGE RT LMKA+QC+RE
Sbjct: 60 KTTMDLNIRDAKKRTALHWACANGRAEVVTLLVDRKCQLDILDGENRTTLMKAVQCQREV 119
Query: 121 CANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAI 180
CANILID+GAD N VDVYGNTA+HYA+ ENL +VA LLS GA IEV+NK TPLLL +
Sbjct: 120 CANILIDSGADPNIVDVYGNTAVHYALIGENLSVVAKLLSCGADIEVKNKTGHTPLLLVM 179
Query: 181 QKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGIT 240
+KRS+Q VEFLLTKNANANA ++ KCTALMLA+C GSSEIVGM+LQ+NVD+ AED G+
Sbjct: 180 RKRSEQIVEFLLTKNANANAVDKFKCTALMLAMCHGSSEIVGMVLQENVDICAEDTWGMI 239
Query: 241 AERYAAACGVN 251
AERYA ACG N
Sbjct: 240 AERYAVACGFN 250
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 328 bits (840), Expect = 3e-89
Identities = 346/1214 (28%), Positives = 552/1214 (45%), Gaps = 122/1214 (10%)
Query: 240 TAERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLL 299
+AE+ AACG++ L + + K + G E PL T ++ +
Sbjct: 156 SAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHIS 215
Query: 300 EKTPDEAARLVEGT-SAKIQCLGKATSGKFEQSTEETPRKILRPT-------KETSEKFS 351
+ L S++ L T + + S++ R+ P K+ +EK +
Sbjct: 216 TRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKAT 275
Query: 352 WPAKERSRKITWEEKE-------TSVKTECVAGVTPNKTEV------LEKGTSNMIACPT 398
K+ I E KE +S K + K V +++G + P
Sbjct: 276 SDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQ 335
Query: 399 KETSTKASTNVDVSSVEPIFSLFG---TRTIENSQ-------CTKVEEDFNLATKIISKS 448
K+++ K VS + + G + T+ + + K + N+AT+I K
Sbjct: 336 KQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEI--KD 393
Query: 449 AAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESSAKTQVCIP 508
Q T + Q +K E+ + + +D E S S + + K
Sbjct: 394 GLQCGTV--SSQKQPALKATTD--EEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 449
Query: 509 ESMYQKVMEIN---REVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ-----TLRAAQM 560
+S+ EI + +K A K + + +V A E+K+ + + R
Sbjct: 450 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 509
Query: 561 FPSESKQKDDEENSWDSESPCE---TVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL- 616
+ S +KD N + E TVS + KAT +E LS EE KDG
Sbjct: 510 LKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREE---KDGEK 566
Query: 617 -----------LKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKA 665
LK T K SL N A K E + S K LK T ++ S+PN A
Sbjct: 567 SRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMA 626
Query: 666 LELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEE 725
E KD + S LK T +K S+ N E+KD Q + S QK +
Sbjct: 627 TETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD------GQQSGTVSSQK---Q 677
Query: 726 NSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKAL 785
+W S + + N AT K+ + G + S + LK T K S+ N A
Sbjct: 678 LAWKATSVKKDSVSNI-----ATEIKD-GQIRGTV--SSQRQPALKATGDEKDSVSNIAR 729
Query: 786 ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGAT-KTVTGQQERD 844
E+KD E + +F K + + +T++ + T+ T+ E
Sbjct: 730 EIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENK 789
Query: 845 IGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNG 904
++ A + + + T ++D + S+ E + + +N + P+ Q +
Sbjct: 790 NSVLNTATKMKDVQTSTPA---EQDLEMASEGEQKRLEEYENNQ--PQVKNQIHSRDDLD 844
Query: 905 KIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKK 964
I +S + S E + + N L + D L KI C+R ELK
Sbjct: 845 DIIQSSQTVS--EDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKD 902
Query: 965 DNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRR 1024
++CEQ+ K+ + KNK VLQK LSE +EIKSQL+++ + E+ELCS+R + QE++KRR
Sbjct: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRR 962
Query: 1025 NVDILKEKIR-----PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESEND 1079
NV+ L +K+R EEQ R + +V + ++ L+ ++ELK+ +N NQVS T E E D
Sbjct: 963 NVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-D 1021
Query: 1080 LFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTK 1139
L HEN +++ EIA L+LE T+K+Q+ E KY +D +I++ K+ +LQ LK ++T+ +
Sbjct: 1022 LLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAE 1079
Query: 1140 RASQYREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKN 1198
+ Y QL LT ENT L SKL K+++ + LETE++S+ RL +AL DHDQS +S+++
Sbjct: 1080 TIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRD 1139
Query: 1199 QELAFHSAGD--APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRE 1256
QELAF D LQ +N V +L L +A+ K + + L+Y G+ L+E
Sbjct: 1140 QELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKE 1192
Query: 1257 NALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQ 1316
ALV EH Q + + Q QMK E MY++ + ++K E+QE + QL+ +N L+QQ
Sbjct: 1193 KALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQ 1248
Query: 1317 LVYAHKKV-NKSKVTINIQFP--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQ 1364
L A K N+ K +NIQ + + ++H L E N+ + N NH KE+ Q
Sbjct: 1249 LDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQ 1308
Query: 1365 YEKEKAEREVSIKK 1378
YEKEKAEREV++++
Sbjct: 1309 YEKEKAEREVAVRQ 1322
Score = 33.9 bits (76), Expect = 1.1
Identities = 98/439 (22%), Positives = 168/439 (38%), Gaps = 54/439 (12%)
Query: 522 VEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ----TLRAAQMFPSESKQKDD--EENSW 575
+E +K A K + +V N A E+K+EQ L A + + S + D +
Sbjct: 18 LEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVT 77
Query: 576 DSESPCETVSQKDVYLP--KATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALE 633
+ E E+ +Y+P K + + + +EE+ + L + V+ ALE
Sbjct: 78 EDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALE 137
Query: 634 --------LKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETL-KAESPDNDGL 684
+R T +S +K L CG ++ + TL + ++ D +G
Sbjct: 138 SENISEPYFTNRRTISQQSAEK---LDAACG---------IDKTENGTLFEDQNVDKEGK 185
Query: 685 LKPTCGRKVSL-----PNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQ 739
P G+K ++ P +KD + + +S +E + S L TL +
Sbjct: 186 ALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL-TLKE 244
Query: 740 NDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVS 799
D KA +++ GK+ S K K T K S+ N A E+K+
Sbjct: 245 ADPS-SKAAMRRKDSPPPGKV--SSQKQPAEKATSDDKDSVSNIATEIKE---------G 292
Query: 800 SVESTFSLFGKPTTENSQSTKVEEDFNLTT--KEG-ATKTVTGQQERDIGIIERAPQDQT 856
+ T S +P E + S + + N+ T KEG + TV+ Q++ +I +
Sbjct: 293 PISGTVSSQKQP-AEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLL 351
Query: 857 NKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHF 916
N G K T S+ + + L AT EIK S +K
Sbjct: 352 NIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIAT---EIKDGLQCGTVSSQKQPAL 408
Query: 917 EPATEMQNSVPNKGLEWKN 935
+ T+ ++SV N E K+
Sbjct: 409 KATTDEEDSVSNIATEIKD 427
Score = 32.7 bits (73), Expect = 2.5
Identities = 28/170 (16%), Positives = 75/170 (44%), Gaps = 17/170 (10%)
Query: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 1259 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREV 1318
Query: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 1319 AVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1378
Query: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
+ +++E Q L ++++ ++ + Q E L H + ML+
Sbjct: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIK--KQDEQIERFEKILQHSSLMLQ 1426
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 322 bits (825), Expect = 2e-87
Identities = 289/894 (32%), Positives = 446/894 (49%), Gaps = 84/894 (9%)
Query: 527 EKPSAFKPAVEMQKTVPNKAFELKN-EQTLRAAQMFPSESKQKDDEENSW--------DS 577
+K A K + + +V N A E+K+ E++ + K DE++S+ D
Sbjct: 162 QKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDG 221
Query: 578 ESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL------------LKPTCGRKV 625
E SQK L KAT KE L+ E+ KDG LK T K
Sbjct: 222 EISRTVSSQKPPAL-KATSVKEDSVLNIAREK---KDGEKSRTVSFEQPPGLKATRDEKD 277
Query: 626 SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLL 685
SL N A KD E + S K LK T ++ S+PN A E KD + S L
Sbjct: 278 SLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPAL 337
Query: 686 KPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLP 745
K T +K S+ N E+KD Q + S QK + +W S + + N
Sbjct: 338 KATSDKKDSVSNIPTEIKD------GQQSGTVSSQK---QPAWKATSVKKDSVSNI---- 384
Query: 746 KATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTF 805
AT K+ + G + S + LK T K S+ N A E+KD E +
Sbjct: 385 -ATEIKD-GQIRGTV--SSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 440
Query: 806 SLFGKPTTENSQSTKVEEDFNLTTKEGAT-KTVTGQQERDIGIIERAPQDQTNKMPTSEL 864
+F K + + +T++ T+ +T+ E ++ A + + + T
Sbjct: 441 VIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA- 499
Query: 865 GRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQN 924
++D + S+ E + + +N + P+ Q + I +S + S E +
Sbjct: 500 --EQDLEMASEGEQKRLEEYENNQ--PQVKNQIHSRDDLDDIIQSSQTVS--EDGDSLCC 553
Query: 925 SVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVL 984
+ N L + D L KI + +R +LK ++CEQ+ K+ + KNK VL
Sbjct: 554 NCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVL 613
Query: 985 QKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIR-----PEEQL 1039
QK +SE +EIKSQL+++ + E+ELCS+R + QE++KRRNV+ L +K+R EEQ
Sbjct: 614 QKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY 673
Query: 1040 RKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLKKEIAMLKLEVA 1099
R + +V + ++ L+ ++ELK+ +N NQVS T E E DL HEN +++ EIA L+LE
Sbjct: 674 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKD 732
Query: 1100 TLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLT 1159
T+K+Q+ E KY +D +I++ K+ +LQ LK +T+ K + Y QL LT ENT L
Sbjct: 733 TIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLR 790
Query: 1160 SKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD--APLQGIMN 1216
SKL K+++ ++ LETE++S+ RL +A DHDQS +S+++QELAF D LQ +N
Sbjct: 791 SKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLN 850
Query: 1217 VDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQCQMK 1276
V +L L +A+ KS+ K L+Y G+ L+E ALV EH Q + + Q QMK
Sbjct: 851 SHVL-------ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMK 903
Query: 1277 KAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKV-NKSKVTINIQF 1335
E MY++ + ++K E+QE + QL+ +N L+QQL A K N+ K +NIQ
Sbjct: 904 DIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQA 959
Query: 1336 P--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKK 1378
+ + ++H L E N+ + N NH KE+ QYEKEKAEREV++++
Sbjct: 960 RCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1013
Score = 65.5 bits (158), Expect = 3e-10
Identities = 188/897 (20%), Positives = 350/897 (39%), Gaps = 141/897 (15%)
Query: 606 KLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKA 665
++E SP K K T K S+ N A E+K+ S K K T K S+ N A
Sbjct: 20 RIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 79
Query: 666 LELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELK--DRETFKAAQMFPSESKQKDD 723
E+K+ + SP K +KVSL N A + + ++Q P+ D
Sbjct: 80 TEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDK 139
Query: 724 EENSWDFESFLETLLQNDVCLP------KATHQKE--FDTLSGKLEE-------SPDKDG 768
+++ + + ++ LQ KAT +E ++ ++++ S K
Sbjct: 140 TDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKP 199
Query: 769 LLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLT 828
LK T K S N E KD E + VSS KP + S K + N+
Sbjct: 200 ALKATSDEKDSFSNITREKKDGEI--SRTVSS--------QKPPALKATSVKEDSVLNIA 249
Query: 829 -TKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKE-------------DTKSTS 874
K+ K+ T E+ G+ +A +D+ + + G+K+ K+TS
Sbjct: 250 REKKDGEKSRTVSFEQPPGL--KATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATS 307
Query: 875 DSEII---SVSDTQNYECLPEATYQKE--IKTTNGKIEESPEKPSHFEPATEMQNSVPNK 929
D E ++T++ + + QK+ +K T+ K + P+ + + K
Sbjct: 308 DKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQK 367
Query: 930 GLEWKNKQTLRADSTT--LSKILD----ALPSCERGRELK-----KDNCEQITAKMEQTK 978
WK +++ DS + ++I D S +R LK KD+ I +++ +
Sbjct: 368 QPAWK-ATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGE 426
Query: 979 NKFCVLQKELSEAKEI---KSQLEN----------QKAKWEQELCSVRLTLNQEEEKRRN 1025
V ++ S K I K L N ++ + L +++ T+ ++
Sbjct: 427 KSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNT 486
Query: 1026 VDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENC 1085
+KE ++ + LE+ + EQ R+++ E + NQ+ H+ + +D+ +
Sbjct: 487 ATKMKE-VQTSTPAEQDLEMASEGEQK-RLEEYE-NNQPQVKNQI-HSRDDLDDIIQSSQ 542
Query: 1086 MLKKE---IAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRAS 1142
+ ++ + V L QH++K + + +L+ KN +K K
Sbjct: 543 TVSEDGDSLCCNCKNVILLIDQHEMKCK---DCVHLLKIKNTFCLWKRLIKLK--DNHCE 597
Query: 1143 QYREQLKVLTAENTMLTSKLKEKQD-KEILETEIESHHPRLASALQDHDQSVTSRKNQEL 1201
Q R +++ L + ++L ++ EK++ K L+ EI L S Q R+N E
Sbjct: 598 QLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEE 657
Query: 1202 AFHSAGD----APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAG------ 1251
+ Q + DV+ I L A+ + K+ N N
Sbjct: 658 LHQKVREKLRITEEQYRIEADVTKPI------KPALKSAEVELKTGGNNSNQVSETDEKE 711
Query: 1252 DDLRENALVSEHAQRDRCETQ-CQMKKAEHMYQNEQDNVD-KHTEQQESLEQ-------- 1301
D L EN L+ + R R E + + E Y + + V KH + Q++L++
Sbjct: 712 DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKT 771
Query: 1302 ------KLFQLESKNRWLRQQLVYAHKKVNKSKVTINIQFPEMKM--------QRHLNEK 1347
+L L +N LR +L ++ ++ ++ +Q ++ Q H +++
Sbjct: 772 IACYSGQLAALTDENTTLRSKL--EKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKR 829
Query: 1348 NEEVFNYG-----NHLKERID--------QYEKEKAEREVSIKKYKYFSNFLKESGL 1391
++E+ G HL+E ++ Q K +++ V + Y LKE L
Sbjct: 830 DQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKAL 886
Score = 32.0 bits (71), Expect = 4.3
Identities = 28/170 (16%), Positives = 74/170 (43%), Gaps = 17/170 (10%)
Query: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 950 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1009
Query: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 1010 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1069
Query: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
+ +++E Q L ++ + ++ + Q E L H + ML+
Sbjct: 1070 TIRCTKEMEGDTQKLEVEHVMMRKIIK--KQDDQIERLEKILQHSSLMLQ 1117
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 317 bits (812), Expect = 5e-86
Identities = 286/903 (31%), Positives = 438/903 (48%), Gaps = 110/903 (12%)
Query: 527 EKPSAFKPAVEMQKTVPNKAFELKN-EQTLRAAQMFPSESKQKDDEENSW--------DS 577
EKP K + + +V N A K+ E+T R + + DE++S+ D
Sbjct: 573 EKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDG 632
Query: 578 ESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL------------LKPTCGRKV 625
E + SQK L K T +E D++ G E+ KDG LK T K
Sbjct: 633 EISRKVSSQKPPAL-KGTSDEE-DSVLGIAREN--KDGEKSRTVSSEKPPGLKATSDEKD 688
Query: 626 SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLL 685
S+ N A KD E + S K LK C ++ S+PN A E KD + S L
Sbjct: 689 SVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
Query: 686 KPTCGRKVSLPNKALELKDRE-----TFKAAQMFPSESKQKDDEENSW----DFESFLET 736
K T +K S+ N E+KD + + + + + S +KD N D +
Sbjct: 749 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
Query: 737 LLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAE 796
+L+ + +++F +L+ SP K K K+SL N A + E
Sbjct: 809 ILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTE 868
Query: 797 DVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQT 856
++ + K T EN S N TK +T T E+D+ + Q +
Sbjct: 869 YPENLPTL-----KATIENKNSV-----LNTATKMKDVQTST-PAEQDLEMASEGEQKRL 917
Query: 857 NKMPTSELGRKEDTKSTSD-SEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSH 915
+ ++ K S D +II S T +
Sbjct: 918 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVS----------------------------- 948
Query: 916 FEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKME 975
E + + N L + D L KI + +R +LK ++CEQ+ K+
Sbjct: 949 -EDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIR 1007
Query: 976 QTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIR- 1034
+ KNK VLQK +SE +EIKSQL+++ + E+ELCS+R + QE++KRRNV+ + +K+R
Sbjct: 1008 KLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVRE 1067
Query: 1035 ----PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLKKE 1090
EEQ R + +V + ++ L+ ++ELK+ +N NQVS T E E DL HEN +++ E
Sbjct: 1068 KLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDE 1126
Query: 1091 IAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKV 1150
IA L+LE T+K+Q+ E KY +D +I++ K+ +LQ LK +T+ K + Y QL
Sbjct: 1127 IARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAA 1184
Query: 1151 LTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD- 1208
LT ENT L SKL K+++ ++ LETE++S+H RL +A DHDQS +S+++QELAF D
Sbjct: 1185 LTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDK 1244
Query: 1209 -APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRD 1267
LQ +N V +L L +A+ KS+ K L+Y G+ L+E ALV EH Q +
Sbjct: 1245 CRHLQENLNSHVL-------ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSE 1297
Query: 1268 RCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKV-NK 1326
+ Q QMK E MY++ + ++K E+QE + QL+ +N L+QQL A K N+
Sbjct: 1298 LKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQ 1353
Query: 1327 SKVTINIQFP--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQYEKEKAEREVS 1375
K +NIQ + + ++H L E N+ + N NH KE+ QYEKEKAEREV+
Sbjct: 1354 EKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVA 1413
Query: 1376 IKK 1378
+++
Sbjct: 1414 VRQ 1416
Score = 56.2 bits (134), Expect = 2e-07
Identities = 220/1060 (20%), Positives = 390/1060 (36%), Gaps = 235/1060 (22%)
Query: 515 VMEINREVEELP-------EKPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQ 567
V I E++E P +K A K + + +V N A E+K Q + S Q
Sbjct: 282 VSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKK------GQQSGTVSPQ 335
Query: 568 KDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSL 627
K +++W + + +K V L + SG + S K K T + S
Sbjct: 336 K---QSAW------KVIFKKKVSLLNIATRIMGGGKSGTV--SSQKQPASKATSDKTDSA 384
Query: 628 PNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKP 687
N A E+KD S K LK T + S+ N A E+KD E S LK
Sbjct: 385 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 444
Query: 688 TCGRKVSLPNKALELKDRET--FKAAQMFPSESKQKDDE--------EN----------- 726
T K S+ N A E+KD E ++Q P+ + D+E EN
Sbjct: 445 TTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSS 504
Query: 727 ---------SWDFESFLE-TLLQNDVCLPKATHQKEFDTLSGKLEE-------------- 762
S + +SF T + D + + ++ TL G +E
Sbjct: 505 RKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDG 564
Query: 763 ------SPDKDGLLKPTCGMKISLPNKALELKDRETFK---------AEDVSSVESTFSL 807
S +K LK + K S+ N A KD E K E S + +FS
Sbjct: 565 EKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSN 624
Query: 808 FGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRK 867
+ + S KV + K A K + +++ +GI + ++ +SE +
Sbjct: 625 ITREKKDGEISRKVS-----SQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSE--KP 677
Query: 868 EDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVP 927
K+TSD + L A +K+ + T + SP++P+ + + ++SVP
Sbjct: 678 PGLKATSD---------EKDSVLNIARGKKDGEKT--RTVSSPKQPA-LKAICDKEDSVP 725
Query: 928 NKGLEWKNKQ-----------TLRADSTTLSKILDALPSCERGRE--------------- 961
N E K++Q L+A S + + + G++
Sbjct: 726 NMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKAT 785
Query: 962 -LKKDNCEQITAKM-------------------EQTKNKFCVLQKELSEAKEIKSQLENQ 1001
+KKD+ I ++ +Q + KF L K + + +S Q
Sbjct: 786 SVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSA---Q 842
Query: 1002 KAKWEQEL----CSVRLT--LNQEEEKRRNVDILKEKIRPE----------EQLRKKLEV 1045
K +++++ + R+T E N+ LK I + + ++
Sbjct: 843 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 902
Query: 1046 KQQLEQTLRIQDIELKSVTSNLNQVS---HTHESENDLFHENCMLKKE---IAMLKLEVA 1099
+Q LE + L+ +N QV H+ + +D+ + + ++ + V
Sbjct: 903 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 962
Query: 1100 TLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLT 1159
L QH++K + + +L+ KN +K K Q R +++ L + ++L
Sbjct: 963 LLIDQHEMKCK---DCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKLKNKASVLQ 1017
Query: 1160 SKLKEKQD-KEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD----APLQGI 1214
++ EK++ K L+ EI L S Q R+N E + Q
Sbjct: 1018 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYR 1077
Query: 1215 MNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAG------DDLRENALVSEHAQRDR 1268
+ DV+ I L A+ + K+ N N D L EN L+ + R R
Sbjct: 1078 IEADVTKPI------KPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLR 1131
Query: 1269 CETQ-CQMKKAEHMYQNEQDNVD-KHTEQQESLEQ--------------KLFQLESKNRW 1312
E + + E Y + + V KH + Q++L++ +L L +N
Sbjct: 1132 LEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTT 1191
Query: 1313 LRQQLVYAHKKVNKSKVTINIQFPEMKM--------QRHLNEKNEEVFNYG-----NHLK 1359
LR +L ++ ++ ++ +Q ++ Q H +++++E+ G HL+
Sbjct: 1192 LRSKL--EKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ 1249
Query: 1360 ERID--------QYEKEKAEREVSIKKYKYFSNFLKESGL 1391
E ++ Q K +++ V + Y LKE L
Sbjct: 1250 ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKAL 1289
Score = 48.9 bits (115), Expect = 3e-05
Identities = 178/872 (20%), Positives = 329/872 (37%), Gaps = 126/872 (14%)
Query: 571 EENSWDSESPCETVSQKDVY-LPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPN 629
EE+S P T++ K+ KA +++ GK+ S K K T K S+ N
Sbjct: 229 EESS--ERPPLSTLTLKEADPSSKAAMRRKDSPPPGKV--SSQKQPAEKATSDDKDSVSN 284
Query: 630 KALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTC 689
A E+K+ S K K T K S+ N A E+K + SP K
Sbjct: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIF 344
Query: 690 GRKVSLPNKALELK--DRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLP-- 745
+KVSL N A + + ++Q P+ D +++ + + ++ LQ
Sbjct: 345 KKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQK 404
Query: 746 ----KATHQKEFDTLSGKLEE----------SPDKDGLLKPTCGMKISLPNKALELKDRE 791
KAT +E D++S E S K LK T K S+ N A E+KD E
Sbjct: 405 QPALKATTDEE-DSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGE 463
Query: 792 ---TFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGII 848
T ++ ++ +T G + ++ E+ +++++ T ++ I
Sbjct: 464 KSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNI 523
Query: 849 ERAPQD-------QTNKMPT---------SELGRKEDTKSTSDSEIIS--------VSDT 884
R +D + K PT S LG + K S +S S
Sbjct: 524 TRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSA 583
Query: 885 QNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADST 944
+ L A +K+ + T K S +KPS E ++ ++S N E K+ + R
Sbjct: 584 EKDSVLNIARGKKDGEKT--KRVSSRKKPS-LEATSDEKDSFSNITREKKDGEISR---- 636
Query: 945 TLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQ------KELSEAKEIKSQL 998
K+ P +G ++D+ I + + + V K S+ K+ +
Sbjct: 637 ---KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNI 693
Query: 999 ENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRPEEQLRKKLE-----VKQQLEQTL 1053
K E+ T++ ++ KE P KK E V Q + L
Sbjct: 694 ARGKKDGEK-----TRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
Query: 1054 RIQDIELKSVTSNLNQVSHTHES------ENDLFHENCMLKKEIAMLKLEV--------A 1099
+ + SV++ ++ +S + + + K ++ + E+
Sbjct: 749 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
Query: 1100 TLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLT 1159
L++ V ++ E L K+A + + QK + K+ L + T
Sbjct: 809 ILEYTFNVMFDQIEEKFTSL-NKSAGVSPQKQSAQKVIFKKKVSL---LNIATRITGGWK 864
Query: 1160 SKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGDAP-LQGIMN-- 1216
S + ++ L+ IE+ + L +A + D ++ Q+L S G+ L+ N
Sbjct: 865 SGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQ 924
Query: 1217 VDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENA-----LVSEHAQRDR-CE 1270
V N I++ + L + +Q S+ GD L N L+ +H + + C
Sbjct: 925 PQVKNQIHSRDDLDDIIQSSQTVSED--------GDSLCCNCKNVILLIDQHEMKCKDCV 976
Query: 1271 TQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQL--------VYAHK 1322
++K +++ D H EQ L K+ +L++K L++++ H+
Sbjct: 977 HLLKIKNTFCLWKRLIKLKDNHCEQ---LRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 1033
Query: 1323 KVNKSKVTINIQF---PEMKMQRHLNEKNEEV 1351
+ K +++F E K +R++ E +++V
Sbjct: 1034 ILELEKELCSLRFAIQQEKKKRRNVEEVHQKV 1065
Score = 37.7 bits (86), Expect = 0.078
Identities = 148/714 (20%), Positives = 262/714 (36%), Gaps = 101/714 (14%)
Query: 522 VEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ----TLRAAQMFPSESKQKDD------E 571
+E +K A K + +V N A E+K+EQ L A + + S + D
Sbjct: 18 LEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVT 77
Query: 572 ENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESP-----VKDGLLKPTCGRKVS 626
EN + ES E +S+ + K + + +EE+ + D +P K +
Sbjct: 78 ENEFSLES--EIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFA 135
Query: 627 LPNKALE---LKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDG 683
L ++ + +R T +S + L CG + ++ + ++ D +G
Sbjct: 136 LESENISEPYFTNRRTISQQSAEN---LDAACGID--------KTENGNMFEDQNVDKEG 184
Query: 684 LLKPTCGRKVSL-----PNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLL 738
P G+K ++ P +KDR+ + +S +E + S L TL
Sbjct: 185 KALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL-TLK 243
Query: 739 QNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDV 798
+ D KA +++ GK+ S K K T K S+ N A E+K+
Sbjct: 244 EADPS-SKAAMRRKDSPPPGKV--SSQKQPAEKATSDDKDSVSNIATEIKE--------- 291
Query: 799 SSVESTFSLFGKPTTENSQSTKVEEDFNLTT---KEGATKTVTGQQERDIGIIERAPQDQ 855
+ T S +P E + S + + N+ T K + TV+ Q++ +I +
Sbjct: 292 GPISGTVSSQKQP-AEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSL 350
Query: 856 TNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSH 915
N G K T S+ + + L AT EIK S +K
Sbjct: 351 LNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIAT---EIKDGLQCGTVSSQKQPA 407
Query: 916 FEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKME 975
+ T+ ++SV N E K+ + S+ L A +KD+ I +++
Sbjct: 408 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTD-------EKDSVSNIATEIK 460
Query: 976 QTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRP 1035
+ K + + A S E +E N++ EK R V R
Sbjct: 461 DGE-KSGTVSSQKPPALTATSDEEGSVLSIARE--------NKDGEKSRTV-----SSRK 506
Query: 1036 EEQLRKKLEVKQQLEQTLR-IQDIELKSVTSN-----LNQVSHTHESENDLFHENCMLKK 1089
+ L+ + K R +D E+ S+ L S +S + EN +K
Sbjct: 507 KPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK 566
Query: 1090 EIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKR-ASQYREQL 1148
+ + LK EK++ L + K TKR +S+ + L
Sbjct: 567 SRTVSSEKPPGLKASS--------------AEKDSVLNIARGKKDGEKTKRVSSRKKPSL 612
Query: 1149 KVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQSV--TSRKNQE 1200
+ + E ++ +EK+D EI ++ S P D + SV +R+N++
Sbjct: 613 EATSDEKDSFSNITREKKDGEI-SRKVSSQKPPALKGTSDEEDSVLGIARENKD 665
Score = 32.0 bits (71), Expect = 4.3
Identities = 28/170 (16%), Positives = 74/170 (43%), Gaps = 17/170 (10%)
Query: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
Query: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 1413 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1472
Query: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
+ +++E Q L ++ + ++ + Q E L H + ML+
Sbjct: 1473 TIRCTKEMEGDTQKLEVEHVMMRKIIK--KQDDQIERLEKILQHSSLMLQ 1520
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 315 bits (807), Expect = 2e-85
Identities = 260/790 (32%), Positives = 403/790 (51%), Gaps = 59/790 (7%)
Query: 610 SPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELK 669
S K LK T K S+ N A K E + S K LK T ++ S+PN A E K
Sbjct: 9 SSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATETK 68
Query: 670 DRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENSWD 729
D + S LK T +K S+ N E+KD Q + S QK + +W
Sbjct: 69 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD------GQQSGTVSSQK---QPAWK 119
Query: 730 FESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKD 789
S + + N AT K+ + G + S + LK T K S+ N A E+KD
Sbjct: 120 ATSVKKDSVSNI-----ATEIKD-GQIRGTV--SSQRQPALKATGDEKDSVSNIAREIKD 171
Query: 790 RETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGAT-KTVTGQQERDIGII 848
E + +F K + + +T++ + T+ T+ E ++
Sbjct: 172 GEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVL 231
Query: 849 ERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEE 908
A + + + T ++D + S+ E + + +N + P+ Q + I +
Sbjct: 232 NTATKMKDVQTSTPA---EQDLEMASEGEQKRLEEYENNQ--PQVKNQIHSRDDLDDIIQ 286
Query: 909 SPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCE 968
S + S E + + N L + D L KI C+R ELK ++CE
Sbjct: 287 SSQTVS--EDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCE 344
Query: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028
Q+ K+ + KNK VLQK LSE +EIKSQL+++ + E+ELCS+R + QE++KRRNV+
Sbjct: 345 QLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEE 404
Query: 1029 LKEKIR-----PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083
L +K+R EEQ R + +V + ++ L+ ++ELK+ +N NQVS T E E DL HE
Sbjct: 405 LHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHE 463
Query: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143
N +++ EIA L+LE T+K+Q+ E KY +D +I++ K+ +LQ LK ++T+ + +
Sbjct: 464 NRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIAC 521
Query: 1144 YREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202
Y QL LT ENT L SKL K+++ + LETE++S+ RL +AL DHDQS +S+++QELA
Sbjct: 522 YSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELA 581
Query: 1203 FHSAGD--APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALV 1260
F D LQ +N V +L L +A+ K + + L+Y G+ L+E ALV
Sbjct: 582 FQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALV 634
Query: 1261 SEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYA 1320
EH Q + + Q QMK E MY++ + ++K E+QE + QL+ +N L+QQL A
Sbjct: 635 FEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDA 690
Query: 1321 HKKV-NKSKVTINIQFP--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQYEKE 1368
K N+ K +NIQ + + ++H L E N+ + N H KE+ QYEKE
Sbjct: 691 RNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKE 750
Query: 1369 KAEREVSIKK 1378
KAEREV++++
Sbjct: 751 KAEREVAVRQ 760
Score = 80.1 bits (196), Expect = 1e-14
Identities = 185/849 (21%), Positives = 319/849 (37%), Gaps = 153/849 (18%)
Query: 528 KPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCE----- 582
K A K + + +VPN A E K+EQ + + ++ S P E
Sbjct: 46 KQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 105
Query: 583 ---TVSQKDVYLPKATHQKEFDTLSGKLEESPVKDG------------LLKPTCGRKVSL 627
TVS + KAT K+ D++S E +KDG LK T K S+
Sbjct: 106 QSGTVSSQKQPAWKATSVKK-DSVSNIATE--IKDGQIRGTVSSQRQPALKATGDEKDSV 162
Query: 628 PNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKP 687
N A E+KD E SP K K +KVSL N A + E P+N LK
Sbjct: 163 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKA 222
Query: 688 TCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLPKA 747
T K S+ N A ++KD +T S ++D E S + LE N +
Sbjct: 223 TIENKNSVLNTATKMKDVQT--------STPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 274
Query: 748 THQKE--FDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAED---VSSVE 802
H ++ D + S D D L C K + L D+ K +D + ++
Sbjct: 275 IHSRDDLDDIIQSSQTVSEDGDSL---CCNCK-----NVILLIDQHEMKCKDCVHLLKIK 326
Query: 803 STFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTS 862
TF L + T E + ++ K Q+
Sbjct: 327 KTFCLCKRLTELKDNHC---EQLRVKIRKLKNKASVLQK--------------------- 362
Query: 863 ELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEM 922
L KE+ KS E + + +KE+ + I++ +K + E E+
Sbjct: 363 RLSEKEEIKSQLKHETLEL--------------EKELCSLRFAIQQEKKKRRNVE---EL 405
Query: 923 QNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQI--TAKMEQTKNK 980
V K + + + AD T I AL S E + +N Q+ T + E ++
Sbjct: 406 HQKVREKLRITEEQYRIEADVT--KPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHE 463
Query: 981 FCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEE----KRRNVDILKEKIR-- 1034
++Q E++ + K ++NQ + ++ L + + E+ +RN + L E I
Sbjct: 464 NRLMQDEIARLRLEKDTIKNQNLE-KKYLKDFEIVKRKHEDLQKALKRNEETLAETIACY 522
Query: 1035 ---------PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQV------SHTHESEND 1079
LR KLE +++ Q L + E++S LN SH+ + + +
Sbjct: 523 SGQLAALTDENTTLRSKLEKQRESGQRL---ETEMQSYRCRLNAALCDHDQSHSSKRDQE 579
Query: 1080 LFHENCM---------LKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKN---AELQ 1127
L + + L + +L L+++ + + +V E + + L+EK +Q
Sbjct: 580 LAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQ 639
Query: 1128 MTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQ 1187
LK KQ + Y+ + NTM K EKQ++ +++ + L L
Sbjct: 640 SELKQKQSQMKDIEKMYK------SGYNTM--EKCIEKQER---FCQLKKQNMLLQQQLD 688
Query: 1188 DHDQSVTSRKNQELAFHSAGDAPLQGI--------MNVDVSNTIYNNEVLHQPLYEAQ-R 1238
D +++ L + DA ++ + + ++ N + NE+ H E Q
Sbjct: 689 DARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYE 748
Query: 1239 KSKSPK----INLNYAGDDLRENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTE 1294
K K+ + L DD+ ++ A D C E+ Q+ + +D+
Sbjct: 749 KEKAEREVAVRQLQQKRDDVLNKGSATK-ALLDASSRHCTY--LENGMQDSRKKLDQMRS 805
Query: 1295 QQESLEQKL 1303
Q + ++ +L
Sbjct: 806 QFQEIQDQL 814
Score = 32.0 bits (71), Expect = 4.3
Identities = 28/170 (16%), Positives = 75/170 (44%), Gaps = 17/170 (10%)
Query: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 697 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREV 756
Query: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 757 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 816
Query: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
+ +++E Q L ++++ ++ + Q E L H + ML+
Sbjct: 817 TIRCTKEMEGDAQKLEVENVMMRKIIK--KQDEQIERFEKILQHSSLMLQ 864
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 314 bits (805), Expect = 3e-85
Identities = 222/600 (37%), Positives = 334/600 (55%), Gaps = 55/600 (9%)
Query: 817 QSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDS 876
Q++ E+D +T+ EG + + G + + E+ + + KM S +D+ + +D
Sbjct: 269 QNSNSEQDLEMTS-EGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDD 327
Query: 877 EIISVSDTQNYECLPEATYQKEI--------KTTNGK---------------IEESPEKP 913
+ +N + + KE KT+N K I S EK
Sbjct: 328 VDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKT 387
Query: 914 SHFE--PATEMQNS---VPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCE 968
S + P ++ +N + G+E K D +LSK +A +C R E +K CE
Sbjct: 388 SEDDELPYSDDENFMLLIKQSGMECK-------DFVSLSKSKNATAACGRSIEDQKCYCE 440
Query: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028
++ K ++ KN VLQK LSE + KSQ E+Q + +++LC++R L Q+EE+R +
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 1029 LKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083
L EK E EQ R + EVK+Q + TL+ ++ELK+V SN NQ HTHE E DL+ E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143
N +++ EIA L+LE+ T+KHQ+Q ENKYF+DI+I++E N +L+ TLK ++T+TK ++
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620
Query: 1144 YREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202
Y ++L VL ENTML S+L KEKQ LETE+ES+ RLA+AL DHDQ +S+++ +LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 1203 FHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSE 1262
F S + + D ++ I ++L Q L +A+ S + L+Y + L+E L E
Sbjct: 681 FQSTVNEWCH--LQEDTNSHI---QILSQQLSKAESTSSGLETELHYEREALKEKTLHIE 735
Query: 1263 HAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHK 1322
H Q TQ +++ EHMYQN+Q ++K+ +Q+S+E LFQL+S+N +QQ A K
Sbjct: 736 HMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARK 795
Query: 1323 KV-NKSKVTINIQF----PEMKMQ---RHLNEKNEEVFNYGNHLKERIDQYEKEKAEREV 1374
K N+ K INIQ K+Q R L E N+ + LKER QYEKEK EREV
Sbjct: 796 KADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEEREV 855
Score = 197 bits (502), Expect = 4e-50
Identities = 118/266 (44%), Positives = 158/266 (59%), Gaps = 6/266 (2%)
Query: 38 DLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKC 97
DLG IH AA G V K+ + ++ + +LN RD K RTAL AC +G VV LV RKC
Sbjct: 38 DLGMIHKAAIAGDVNKVME-SILLRLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKC 96
Query: 98 QLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVAT 157
QLN+ D E RT L+KA+QC+ E CA+IL++ GA+ N D+YGNTALHYA+ +EN+ M
Sbjct: 97 QLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARK 156
Query: 158 LLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGS 217
LL+YGA IE +++ T LLLA+ ++ +Q V FLL K + A + TAL+LA GS
Sbjct: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGS 216
Query: 218 SEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEH-IRKLPKNPQNTNPEG- 275
+ +V LLQ N+DVF +DI G TAE YA A I + E+ K K+ QN+N E
Sbjct: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQD 276
Query: 276 ---TSTGTPDEAAPLAERTPDTAESL 298
TS G + P E +
Sbjct: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 314 bits (805), Expect = 3e-85
Identities = 222/600 (37%), Positives = 334/600 (55%), Gaps = 55/600 (9%)
Query: 817 QSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDS 876
Q++ E+D +T+ EG + + G + + E+ + + KM S +D+ + +D
Sbjct: 269 QNSNSEQDLEMTS-EGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDD 327
Query: 877 EIISVSDTQNYECLPEATYQKEI--------KTTNGK---------------IEESPEKP 913
+ +N + + KE KT+N K I S EK
Sbjct: 328 VDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKT 387
Query: 914 SHFE--PATEMQNS---VPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCE 968
S + P ++ +N + G+E K D +LSK +A +C R E +K CE
Sbjct: 388 SEDDELPYSDDENFMLLIKQSGMECK-------DFVSLSKSKNATAACGRSIEDQKCYCE 440
Query: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028
++ K ++ KN VLQK LSE + KSQ E+Q + +++LC++R L Q+EE+R +
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 1029 LKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083
L EK E EQ R + EVK+Q + TL+ ++ELK+V SN NQ HTHE E DL+ E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143
N +++ EIA L+LE+ T+KHQ+Q ENKYF+DI+I++E N +L+ TLK ++T+TK ++
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620
Query: 1144 YREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202
Y ++L VL ENTML S+L KEKQ LETE+ES+ RLA+AL DHDQ +S+++ +LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 1203 FHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSE 1262
F S + + D ++ I ++L Q L +A+ S + L+Y + L+E L E
Sbjct: 681 FQSTVNEWCH--LQEDTNSHI---QILSQQLSKAESTSSGLETELHYEREALKEKTLHIE 735
Query: 1263 HAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHK 1322
H Q TQ +++ EHMYQN+Q ++K+ +Q+S+E LFQL+S+N +QQ A K
Sbjct: 736 HMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARK 795
Query: 1323 KV-NKSKVTINIQF----PEMKMQ---RHLNEKNEEVFNYGNHLKERIDQYEKEKAEREV 1374
K N+ K INIQ K+Q R L E N+ + LKER QYEKEK EREV
Sbjct: 796 KADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEEREV 855
Score = 197 bits (502), Expect = 4e-50
Identities = 118/266 (44%), Positives = 158/266 (59%), Gaps = 6/266 (2%)
Query: 38 DLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKC 97
DLG IH AA G V K+ + ++ + +LN RD K RTAL AC +G VV LV RKC
Sbjct: 38 DLGMIHKAAIAGDVNKVME-SILLRLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKC 96
Query: 98 QLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVAT 157
QLN+ D E RT L+KA+QC+ E CA+IL++ GA+ N D+YGNTALHYA+ +EN+ M
Sbjct: 97 QLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARK 156
Query: 158 LLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGS 217
LL+YGA IE +++ T LLLA+ ++ +Q V FLL K + A + TAL+LA GS
Sbjct: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGS 216
Query: 218 SEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEH-IRKLPKNPQNTNPEG- 275
+ +V LLQ N+DVF +DI G TAE YA A I + E+ K K+ QN+N E
Sbjct: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQD 276
Query: 276 ---TSTGTPDEAAPLAERTPDTAESL 298
TS G + P E +
Sbjct: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 312 bits (800), Expect = 1e-84
Identities = 221/600 (36%), Positives = 333/600 (55%), Gaps = 55/600 (9%)
Query: 817 QSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDS 876
Q++ E+D +T+ EG + + G + + E+ + + KM S +D+ + +D
Sbjct: 269 QNSNSEQDLEMTS-EGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDD 327
Query: 877 EIISVSDTQNYECLPEATYQKEI--------KTTNGK---------------IEESPEKP 913
+ +N + + KE KT+N K I S EK
Sbjct: 328 VDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKT 387
Query: 914 SHFE--PATEMQNS---VPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCE 968
S + P ++ +N + G+E K D +LSK +A +C R E +K CE
Sbjct: 388 SEDDELPYSDDENFMLLIEQSGMECK-------DFVSLSKSKNATAACGRSIEDQKCYCE 440
Query: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028
++ K ++ KN VLQK LSE + KSQ E+Q + +++LC++R L Q+EE+R +
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 1029 LKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083
L EK E EQ R + EVK+Q + TL+ ++ELK+V SN NQ HTHE E DL+ E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143
N +++ EIA L+LE+ T+KHQ+Q ENKYF+DI+I++E N +L+ TLK ++ +TK ++
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITR 620
Query: 1144 YREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202
Y ++L VL ENTML S+L KEKQ LETE+ES+ RLA+AL DHDQ +S+++ +LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 1203 FHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSE 1262
F S + + D ++ I ++L Q L +A+ S + L+Y + L+E L E
Sbjct: 681 FQSTVNEWCH--LQEDTNSHI---QILSQQLSKAESTSSGLETELHYEREALKEKTLHIE 735
Query: 1263 HAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHK 1322
H Q TQ +++ EHMYQN+Q ++K+ +Q+S+E LFQL+S+N +QQ A K
Sbjct: 736 HMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARK 795
Query: 1323 KV-NKSKVTINIQF----PEMKMQ---RHLNEKNEEVFNYGNHLKERIDQYEKEKAEREV 1374
K N+ K INIQ K+Q R L E N+ + LKER QYEKEK EREV
Sbjct: 796 KADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEEREV 855
Score = 197 bits (500), Expect = 8e-50
Identities = 118/266 (44%), Positives = 158/266 (59%), Gaps = 6/266 (2%)
Query: 38 DLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKC 97
DLG IH AA G V K+ + ++ + +LN RD K RTAL AC +G VV LV RKC
Sbjct: 38 DLGMIHKAAIAGDVNKVME-SILLRLNDLNDRDKKNRTALLLACAHGRPGVVADLVARKC 96
Query: 98 QLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVAT 157
QLN+ D E RT L+KA+QC+ E CA+IL++ GA+ N D+YGNTALHYA+ +EN+ M
Sbjct: 97 QLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARK 156
Query: 158 LLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGS 217
LL+YGA IE +++ T LLLA+ ++ +Q V FLL K + A + TAL+LA GS
Sbjct: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRTALILAARNGS 216
Query: 218 SEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEH-IRKLPKNPQNTNPEG- 275
+ +V LLQ N+DVF +DI G TAE YA A I + E+ K K+ QN+N E
Sbjct: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQD 276
Query: 276 ---TSTGTPDEAAPLAERTPDTAESL 298
TS G + P E +
Sbjct: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 305 bits (781), Expect = 2e-82
Identities = 197/469 (42%), Positives = 288/469 (61%), Gaps = 34/469 (7%)
Query: 939 LRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQL 998
L D L KI + +R +LK ++CEQ+ K+ + KNK VLQK +SE +EIKSQL
Sbjct: 21 LVTDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 80
Query: 999 ENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIR-----PEEQLRKKLEVKQQLEQTL 1053
+++ + E+ELCS+R + QE++KRRNV+ L +K+R EEQ R + +V + ++ L
Sbjct: 81 KHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPAL 140
Query: 1054 RIQDIELKSVTSNLNQVSHTHESENDLFHENCMLKKEIAMLKLEVATLKHQHQVKENKYF 1113
+ ++ELK+ +N NQVS T E E DL HEN +++ EIA L+L+ T+K+Q+ E KY
Sbjct: 141 KSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLDTDTIKNQN--LEKKYL 197
Query: 1114 EDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKL-KEKQDKEILE 1172
+D +I++ K+ +LQ LK +T+ K + Y QL LT ENT L SKL K+++ ++ LE
Sbjct: 198 KDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLE 257
Query: 1173 TEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD--APLQGIMNVDVSNTIYNNEVLH 1230
TE++S+H RL +A DHDQS +S+++QELAF D LQ +N V +L
Sbjct: 258 TEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILS 310
Query: 1231 QPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVD 1290
L +A+ KS+ K L+Y G+ L+E ALV EH Q + + Q QMK E MY++ + ++
Sbjct: 311 LQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 370
Query: 1291 KHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKV-NKSKVTINIQFP--------EMKMQ 1341
K E+QE + QL+ +N L+QQL A K N+ K +NIQ + + +
Sbjct: 371 KCIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECR 426
Query: 1342 RH---LNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYFSNFLK 1387
+H L E N+ + N NH KE+ QYEKEKAEREVSIKK KYFSNFLK
Sbjct: 427 KHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVSIKKNKYFSNFLK 475
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 293 bits (751), Expect = 6e-79
Identities = 195/556 (35%), Positives = 303/556 (54%), Gaps = 52/556 (9%)
Query: 869 DTKSTSDSEIISVSDTQNYECLPEA--------TYQKEIKTTNGKIEESPEKPSHFEPAT 920
D+ S D E++SV+ Q C+PE ++ K + NGK E P K +P+T
Sbjct: 283 DSLSALDDELLSVAAKQ---CVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPST 339
Query: 921 EMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNK 980
EM++ ++ KN QTLRA+ ALP + +++ E+ ++ + N
Sbjct: 340 EMEDPAVKGAVQXKNVQTLRAEQ--------ALPVASEEEQQRRERSEKKQPQVIEGNNT 391
Query: 981 FCVLQKELSE----------AKEIKSQLE---------NQKAKWEQELCSVRLTLNQEEE 1021
+ + +LSE A + Q + +K K E + C TL QE E
Sbjct: 392 YKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENE 447
Query: 1022 KRRNVDILKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHES 1076
++ NV++L +K R E +Q +K++E KQ LE T++ +++ K+ + NQ H HE
Sbjct: 448 EKTNVNMLHKKNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARNTPNQDFHNHEE 506
Query: 1077 ENDLFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKT 1136
DL ENC+LK +IA+L+ E+ T+K+ + KENKY +DIKI +E NA L+ +KL ++
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
Query: 1137 VTKRASQYREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTS 1195
+TK A Y+++L L AENT L S+L KEK+ K+ LE EIES+ RLA+A+ H ++V +
Sbjct: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
Query: 1196 RKNQELAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLR 1255
+N +LA D Q M+ D+S N L + L + Q K + K D LR
Sbjct: 627 ERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLR 686
Query: 1256 ENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQ 1315
+ +L E Q D +TQ Q+K+ + MYQ+ + V K T + +E+++ QL+ +N WL Q
Sbjct: 687 KKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQ 746
Query: 1316 QLVYAHKKVNKSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAER 1372
QLV H+K + ++ INIQ K L EKN+++ N +HLKE + QYE++KAE
Sbjct: 747 QLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAET 806
Query: 1373 EVSIKKYKYFSNFLKE 1388
VSIK+ KYF K+
Sbjct: 807 VVSIKEDKYFQTSRKK 822
Score = 217 bits (552), Expect = 7e-56
Identities = 171/531 (32%), Positives = 265/531 (49%), Gaps = 63/531 (11%)
Query: 23 ERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACV 82
+ +YT Y I + +L KIH AA +G ++E+ + ++ +L+ D + RTALH AC
Sbjct: 19 DHLYTGSGY-RIRYSELQKIHKAAVKGDAAEMERC-LARRSGDLDALDKQHRTALHLACA 76
Query: 83 NGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTA 142
+GH +VVT LV+RKCQ+++ D E RTPL++A+ C+ EACA IL++ GA+ N D+YGNTA
Sbjct: 77 SGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTA 136
Query: 143 LHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFN 202
LHYAVYSE+ + LL +G IE +K S TPLL AI + ++ VEFLL A+ +A +
Sbjct: 137 LHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVD 196
Query: 203 ESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEHIR 262
+ TALMLA+ S IV +LL+Q+++VF +D+ G AE YA +C + I QQ+LEH +
Sbjct: 197 RLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHKK 256
Query: 263 KLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEAARLVEGTSAKIQCL 320
+ KN + G+ DE+A E D+ +L ++ AA+ QC+
Sbjct: 257 MILKN------DKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAK---------QCV 301
Query: 321 GKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTP 380
+ S + +I+ E PAK S K + E ++ +VK V
Sbjct: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGP-----PAKHPSLKPSTEMEDPAVK----GAVQX 352
Query: 381 NKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTIENSQCTKVEEDFNL 440
+ L + +A ++ + S +E G T ++ K++ N+
Sbjct: 353 KNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIE------GNNTYKSE---KIQLSENI 403
Query: 441 ATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESS 500
S +A + T Q+ I K Q FP + K E D E+
Sbjct: 404 CHSTFSAAADR-------LTQQRKI----GKTYPQQFPKKLKEEHDR-----CTLKQENE 447
Query: 501 AKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-KAFELK 550
KT V +M K + EEL K +K VE ++ P ++ E+K
Sbjct: 448 EKTNV----NMLHK-----KNREELERKEKQYKKEVEAKQLEPTVQSLEMK 489
Score = 60.5 bits (145), Expect = 1e-08
Identities = 115/555 (20%), Positives = 205/555 (36%), Gaps = 93/555 (16%)
Query: 500 SAKTQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELK 550
S + C+PE + + + +N + E P K + KP+ EM+ A + K
Sbjct: 294 SVAAKQCVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXK 353
Query: 551 NEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEES 610
N QTLRA Q P S+++ + + P V T++ E LS + S
Sbjct: 354 NVQTLRAEQALPVASEEEQQRRERSEKKQP-------QVIEGNNTYKSEKIQLSENICHS 406
Query: 611 PVKDGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNK 664
+ T RK+ P K E DR T K E+ +K +
Sbjct: 407 TFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------N 453
Query: 665 ALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDE 724
L K+RE L+ + K +++ ++LE+K K A+ P++ +E
Sbjct: 454 MLHKKNREELERKEKQ---YKKEVEAKQLEPTVQSLEMKP----KTARNTPNQDFHNHEE 506
Query: 725 -ENSWDFESFLET---LLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL 780
++ D L+T +L+ ++C K + ++ + ++ + + + L+ + +
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
Query: 781 PNKAL-------------------ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKV 821
K EL + K + + +ES S +++S++ K
Sbjct: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
Query: 822 EEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISV 881
E + L + + + DI IE N T +L + + +T +
Sbjct: 627 ERNLKLALERTQDISEQVKMSSDISEIE-----DKNXFLTEQLSKMQIKFNTLKDKFRKT 681
Query: 882 SDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFE----PATEMQNSVPNKGLE----- 932
DT + L T Q ++ T +I+E E E +T N V + +
Sbjct: 682 RDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQREN 741
Query: 933 -WKNKQTLRADSTTLSKILDALPSCERG--RELKKDNCEQITAKMEQTKNKFCVLQKELS 989
W +Q + K + + + +RG KKD M + KNK L E
Sbjct: 742 PWLEQQLVDVHQKEDHK--EIVINIQRGFIESRKKD-------LMLEEKNK--KLMNEYD 790
Query: 990 EAKEIKSQLENQKAK 1004
KE Q E QKA+
Sbjct: 791 HLKESLFQYERQKAE 805
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 293 bits (751), Expect = 6e-79
Identities = 195/556 (35%), Positives = 303/556 (54%), Gaps = 52/556 (9%)
Query: 869 DTKSTSDSEIISVSDTQNYECLPEA--------TYQKEIKTTNGKIEESPEKPSHFEPAT 920
D+ S D E++SV+ Q C+PE ++ K + NGK E P K +P+T
Sbjct: 283 DSLSALDDELLSVAAKQ---CVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPST 339
Query: 921 EMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNK 980
EM++ ++ KN QTLRA+ ALP + +++ E+ ++ + N
Sbjct: 340 EMEDPAVKGAVQXKNVQTLRAEQ--------ALPVASEEEQQRRERSEKKQPQVIEGNNT 391
Query: 981 FCVLQKELSE----------AKEIKSQLE---------NQKAKWEQELCSVRLTLNQEEE 1021
+ + +LSE A + Q + +K K E + C TL QE E
Sbjct: 392 YKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENE 447
Query: 1022 KRRNVDILKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHES 1076
++ NV++L +K R E +Q +K++E KQ LE T++ +++ K+ + NQ H HE
Sbjct: 448 EKTNVNMLHKKNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARNTPNQDFHNHEE 506
Query: 1077 ENDLFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKT 1136
DL ENC+LK +IA+L+ E+ T+K+ + KENKY +DIKI +E NA L+ +KL ++
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
Query: 1137 VTKRASQYREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTS 1195
+TK A Y+++L L AENT L S+L KEK+ K+ LE EIES+ RLA+A+ H ++V +
Sbjct: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
Query: 1196 RKNQELAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLR 1255
+N +LA D Q M+ D+S N L + L + Q K + K D LR
Sbjct: 627 ERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLR 686
Query: 1256 ENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQ 1315
+ +L E Q D +TQ Q+K+ + MYQ+ + V K T + +E+++ QL+ +N WL Q
Sbjct: 687 KKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQ 746
Query: 1316 QLVYAHKKVNKSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAER 1372
QLV H+K + ++ INIQ K L EKN+++ N +HLKE + QYE++KAE
Sbjct: 747 QLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAET 806
Query: 1373 EVSIKKYKYFSNFLKE 1388
VSIK+ KYF K+
Sbjct: 807 VVSIKEDKYFQTSRKK 822
Score = 217 bits (552), Expect = 7e-56
Identities = 171/531 (32%), Positives = 265/531 (49%), Gaps = 63/531 (11%)
Query: 23 ERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACV 82
+ +YT Y I + +L KIH AA +G ++E+ + ++ +L+ D + RTALH AC
Sbjct: 19 DHLYTGSGY-RIRYSELQKIHKAAVKGDAAEMERC-LARRSGDLDALDKQHRTALHLACA 76
Query: 83 NGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTA 142
+GH +VVT LV+RKCQ+++ D E RTPL++A+ C+ EACA IL++ GA+ N D+YGNTA
Sbjct: 77 SGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTA 136
Query: 143 LHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFN 202
LHYAVYSE+ + LL +G IE +K S TPLL AI + ++ VEFLL A+ +A +
Sbjct: 137 LHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVD 196
Query: 203 ESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEHIR 262
+ TALMLA+ S IV +LL+Q+++VF +D+ G AE YA +C + I QQ+LEH +
Sbjct: 197 RLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHKK 256
Query: 263 KLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEAARLVEGTSAKIQCL 320
+ KN + G+ DE+A E D+ +L ++ AA+ QC+
Sbjct: 257 MILKN------DKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAK---------QCV 301
Query: 321 GKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTP 380
+ S + +I+ E PAK S K + E ++ +VK V
Sbjct: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGP-----PAKHPSLKPSTEMEDPAVK----GAVQX 352
Query: 381 NKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTIENSQCTKVEEDFNL 440
+ L + +A ++ + S +E G T ++ K++ N+
Sbjct: 353 KNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIE------GNNTYKSE---KIQLSENI 403
Query: 441 ATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESS 500
S +A + T Q+ I K Q FP + K E D E+
Sbjct: 404 CHSTFSAAADR-------LTQQRKI----GKTYPQQFPKKLKEEHDR-----CTLKQENE 447
Query: 501 AKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-KAFELK 550
KT V +M K + EEL K +K VE ++ P ++ E+K
Sbjct: 448 EKTNV----NMLHK-----KNREELERKEKQYKKEVEAKQLEPTVQSLEMK 489
Score = 60.5 bits (145), Expect = 1e-08
Identities = 115/555 (20%), Positives = 205/555 (36%), Gaps = 93/555 (16%)
Query: 500 SAKTQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELK 550
S + C+PE + + + +N + E P K + KP+ EM+ A + K
Sbjct: 294 SVAAKQCVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXK 353
Query: 551 NEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEES 610
N QTLRA Q P S+++ + + P V T++ E LS + S
Sbjct: 354 NVQTLRAEQALPVASEEEQQRRERSEKKQP-------QVIEGNNTYKSEKIQLSENICHS 406
Query: 611 PVKDGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNK 664
+ T RK+ P K E DR T K E+ +K +
Sbjct: 407 TFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------N 453
Query: 665 ALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDE 724
L K+RE L+ + K +++ ++LE+K K A+ P++ +E
Sbjct: 454 MLHKKNREELERKEKQ---YKKEVEAKQLEPTVQSLEMKP----KTARNTPNQDFHNHEE 506
Query: 725 -ENSWDFESFLET---LLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL 780
++ D L+T +L+ ++C K + ++ + ++ + + + L+ + +
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
Query: 781 PNKAL-------------------ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKV 821
K EL + K + + +ES S +++S++ K
Sbjct: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
Query: 822 EEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISV 881
E + L + + + DI IE N T +L + + +T +
Sbjct: 627 ERNLKLALERTQDISEQVKMSSDISEIE-----DKNXFLTEQLSKMQIKFNTLKDKFRKT 681
Query: 882 SDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFE----PATEMQNSVPNKGLE----- 932
DT + L T Q ++ T +I+E E E +T N V + +
Sbjct: 682 RDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQREN 741
Query: 933 -WKNKQTLRADSTTLSKILDALPSCERG--RELKKDNCEQITAKMEQTKNKFCVLQKELS 989
W +Q + K + + + +RG KKD M + KNK L E
Sbjct: 742 PWLEQQLVDVHQKEDHK--EIVINIQRGFIESRKKD-------LMLEEKNK--KLMNEYD 790
Query: 990 EAKEIKSQLENQKAK 1004
KE Q E QKA+
Sbjct: 791 HLKESLFQYERQKAE 805
>gi|239744894 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 197
Score = 275 bits (703), Expect = 2e-73
Identities = 143/193 (74%), Positives = 160/193 (82%), Gaps = 2/193 (1%)
Query: 61 KKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREA 120
K ++ N RD KKRTALHWAC NGHAEVVT LVDRKCQL+VLDGE TPLMKA+QC+RE
Sbjct: 4 KTTMDPNIRDAKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQREV 63
Query: 121 CANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAI 180
CANILID+GAD N VDVY NTA+HYAVY ENL +VA LLS GA I+V+NKA TPLLLAI
Sbjct: 64 CANILIDSGADPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAGHTPLLLAI 123
Query: 181 QKRSKQTVEFLLTKNANANA--FNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHG 238
+KRS+Q VEFLLTKNANANA ++ KCTALMLAIC GSSEIVGM+LQQNVD+ A D G
Sbjct: 124 RKRSEQIVEFLLTKNANANANSVDKFKCTALMLAICHGSSEIVGMVLQQNVDICAVDTCG 183
Query: 239 ITAERYAAACGVN 251
+ AERYA ACG N
Sbjct: 184 MIAERYAVACGFN 196
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens]
Length = 823
Score = 274 bits (700), Expect = 5e-73
Identities = 183/545 (33%), Positives = 298/545 (54%), Gaps = 32/545 (5%)
Query: 869 DTKSTSDSEIISVSDTQNY-----ECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQ 923
D+ SD + ++V+ Q E LP ++++K + NG+ E P K +P+TE++
Sbjct: 283 DSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVE 342
Query: 924 NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR----ELKKDNCEQITAKMEQTKN 979
+ ++ KN QTLRA+ + ER ++K+ N + K++ ++N
Sbjct: 343 DPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSEN 402
Query: 980 KFC-----VLQKELSEAKEIKSQLENQ---KAKWEQELCSVRLTLNQEEEKRRNVDILKE 1031
C L++ ++I Q K K E + C TL QE E++ NV++L +
Sbjct: 403 -ICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLYK 457
Query: 1032 KIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCM 1086
K R E +Q +K++E KQ LE T++ +++ K+ + N+ H HE L ENC+
Sbjct: 458 KNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI 516
Query: 1087 LKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYRE 1146
LK +IA+L+ E+ T+K+ + KENKY +DIKI++E NA L+ +KL ++ +T+ A +Y++
Sbjct: 517 LKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQ 576
Query: 1147 QLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHS 1205
+L L AENT L ++L KEK+ K+ LE +IES+ RLA+A+ H +SV + +N +LA
Sbjct: 577 ELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALER 636
Query: 1206 AGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQ 1265
D +Q M+ +S NE L + L E Q K + K D LR+ +L E Q
Sbjct: 637 TRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQ 696
Query: 1266 RDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVN 1325
D +TQ Q ++ + MYQN + V+ T + +E+++ L+ +N WL QQL H+K +
Sbjct: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKED 756
Query: 1326 KSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYF 1382
++ NIQ K L EK++++ N +HLKE + QYE+EK E VSIK+ KYF
Sbjct: 757 HKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYF 816
Query: 1383 SNFLK 1387
K
Sbjct: 817 QTSRK 821
Score = 224 bits (571), Expect = 4e-58
Identities = 182/547 (33%), Positives = 277/547 (50%), Gaps = 63/547 (11%)
Query: 9 GKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNK 68
G G R + + VYT Y I +L KIH AA +G ++E+ + ++ +L+
Sbjct: 5 GFGSRRGQTAQGSIDHVYTGSGY-RIRDSELQKIHRAAVKGDAAEVERC-LARRSGDLDA 62
Query: 69 RDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDA 128
D + RTALH AC +GH +VVT LV+RKCQ++V D E RTPL++A+ C+ EACA IL++
Sbjct: 63 LDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEH 122
Query: 129 GADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTV 188
GA+ N D+YGNTALHYAVYSE+ + LLS+GA IE +K + TPLL AI + ++ V
Sbjct: 123 GANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMV 182
Query: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248
EFLL + A+++A + + +ALMLA+ S IV +LL+QN+DVFA+D+ G AE YA +
Sbjct: 183 EFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISH 242
Query: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEA 306
+ I QQ+LEH +K+ K E + G+ DE+A E D+ + +K + A
Sbjct: 243 HLTKIQQQILEHKKKILKK------EKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVA 296
Query: 307 ARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEK 366
+ QC+ + S S+ E +I+ E PAK S K + E +
Sbjct: 297 TK---------QCVPEKVSEPLPGSSHEKGNRIVNGQGEGP-----PAKHPSLKPSTEVE 342
Query: 367 ETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTI 426
+ +VK V + L + +A ++ + S E G T
Sbjct: 343 DPAVK----GAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKE------GNNT- 391
Query: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREED 486
++ K++ N+ S +A + T Q+ I K Q FP + K E D
Sbjct: 392 --NKSEKIQLSENICDSTSSAAAGR-------LTQQRKI----GKTYPQQFPKKLKEEHD 438
Query: 487 EEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-K 545
E+ KT V +Y+K NR EEL K +K VE ++ P +
Sbjct: 439 R-----CTLKQENEEKTNV---NMLYKK----NR--EELERKEKQYKKEVEAKQLEPTVQ 484
Query: 546 AFELKNE 552
+ E+K++
Sbjct: 485 SLEMKSK 491
Score = 58.5 bits (140), Expect = 4e-08
Identities = 97/464 (20%), Positives = 178/464 (38%), Gaps = 55/464 (11%)
Query: 744 LPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVES 803
LP ++H+K ++G+ E P K LKP+ ++ A++ K+ +T +AE V S
Sbjct: 309 LPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVAS 368
Query: 804 TFSLFGKPTTENSQ-----------STKVEEDFNLTTKEGATKTVTGQQERDIGIIERAP 852
+E Q S K++ N+ + Q+R IG + P
Sbjct: 369 EEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIG--KTYP 426
Query: 853 QDQTNKMPT--SELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEI--KTTNGKIE- 907
Q K+ K++ + ++ ++ + + E E Y+KE+ K ++
Sbjct: 427 QQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELE-RKEKQYKKEVEAKQLEPTVQS 485
Query: 908 -ESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDN 966
E K + P + N KGL +N L+AD L + + + + +E K
Sbjct: 486 LEMKSKTARNTPNRDFHNHEEMKGLMDEN-CILKADIAILRQEICTMKNDNLEKENKYLK 544
Query: 967 CEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNV 1026
+I + K+ L +E+ + Q E K E + L +E +KR
Sbjct: 545 DIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEA 604
Query: 1027 DI-------------LKEKIRPEEQLRKKLE----VKQQLEQTLRIQDI--ELKSVTSNL 1067
DI E ++ E L+ LE V Q+E + I + E + +T L
Sbjct: 605 DIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQL 664
Query: 1068 NQVSHTHESENDLFHE--NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAE 1125
++ + D F + + + KK +A+ ++ + Q Q +E K E
Sbjct: 665 SETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMK-------------E 711
Query: 1126 LQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKE 1169
+ + K T + + E++ L EN L +L + KE
Sbjct: 712 MYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKE 755
Score = 50.8 bits (120), Expect = 9e-06
Identities = 113/557 (20%), Positives = 205/557 (36%), Gaps = 69/557 (12%)
Query: 503 TQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ 553
T+ C+PE + + + +N + E P K + KP+ E++ A + KN Q
Sbjct: 297 TKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQ 356
Query: 554 TLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVK 613
TLRA Q P S+++ + + + P V T++ E LS + +S
Sbjct: 357 TLRAEQALPVASEEEQERHERSEKKQP-------QVKEGNNTNKSEKIQLSENICDSTSS 409
Query: 614 DGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALE 667
+ T RK+ P K E DR T K E+ +K + + L K +
Sbjct: 410 AAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQ 469
Query: 668 LKDRETLKAESPDNDGL-LKPTCGRKVSLPNKALE-------LKDRETFKAAQMFPSESK 719
K K P L +K R + PN+ L D A + +
Sbjct: 470 YKKEVEAKQLEPTVQSLEMKSKTAR--NTPNRDFHNHEEMKGLMDENCILKADIAILRQE 527
Query: 720 ----QKDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCG 775
+ D+ E + ++ + + + L K E + + L
Sbjct: 528 ICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTR 587
Query: 776 MKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATK 835
+ L LK++E+ K + + +ES S +++S+S K E + L + T+
Sbjct: 588 LNAEL------LKEKESKKRLE-ADIESYQSRLAAAISKHSESVKTERNLKLALER--TR 638
Query: 836 TVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATY 895
V+ Q E I + N+ T +L + + + D+ + L T
Sbjct: 639 DVSVQVEMSSAI---SKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETV 695
Query: 896 QKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPS 955
Q ++ T + +E E + E ++ NS + L+ ++ L + LD +
Sbjct: 696 QNDLSQTQQQTQEMKEMYQNAE--AKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV-- 751
Query: 956 CERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLT 1015
K+D+ E +T +Q+ E+ + LE + K E ++ +
Sbjct: 752 -----HQKEDHKEIVTN-----------IQRGFIESGKKDLVLEEKSKKLMNECDHLKES 795
Query: 1016 LNQ-EEEKRRNVDILKE 1031
L Q E EK V +KE
Sbjct: 796 LFQYEREKTEGVVSIKE 812
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens]
Length = 823
Score = 273 bits (699), Expect = 6e-73
Identities = 183/546 (33%), Positives = 299/546 (54%), Gaps = 32/546 (5%)
Query: 869 DTKSTSDSEIISVSDTQNY-----ECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQ 923
D+ SD + ++V+ Q E LP ++++K + NG+ E P K +P+TE++
Sbjct: 283 DSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVE 342
Query: 924 NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR----ELKKDNCEQITAKMEQTKN 979
+ ++ KN QTLRA+ + ER ++K+ N + K++ ++N
Sbjct: 343 DPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSEN 402
Query: 980 KFC-----VLQKELSEAKEIKSQLENQ---KAKWEQELCSVRLTLNQEEEKRRNVDILKE 1031
C L++ ++I Q K K E + C TL QE E++ NV++L +
Sbjct: 403 -ICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLYK 457
Query: 1032 KIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCM 1086
K R E +Q +K++E KQ LE T++ +++ K+ + N+ H HE L ENC+
Sbjct: 458 KNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI 516
Query: 1087 LKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYRE 1146
LK +IA+L+ E+ T+K+ + KENKY +DIKI++E NA L+ +KL ++ +T+ A +Y++
Sbjct: 517 LKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQ 576
Query: 1147 QLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHS 1205
+L L AENT L ++L KEK+ K+ LE +IES+ RLA+A+ H +SV + +N +LA
Sbjct: 577 ELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALER 636
Query: 1206 AGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQ 1265
D +Q M+ +S NE L + L E Q K + K D LR+ +L E Q
Sbjct: 637 TRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQ 696
Query: 1266 RDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVN 1325
D +TQ Q ++ + MYQN + V+ T + +E+++ L+ +N WL QQL H+K +
Sbjct: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKED 756
Query: 1326 KSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYF 1382
++ NIQ K L EK++++ N +HLKE + QYE+EK E VSIK+ KYF
Sbjct: 757 HKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYF 816
Query: 1383 SNFLKE 1388
K+
Sbjct: 817 QTSRKK 822
Score = 224 bits (571), Expect = 4e-58
Identities = 182/547 (33%), Positives = 277/547 (50%), Gaps = 63/547 (11%)
Query: 9 GKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNK 68
G G R + + VYT Y I +L KIH AA +G ++E+ + ++ +L+
Sbjct: 5 GFGSRRGQTAQGSIDHVYTGSGY-RIRDSELQKIHRAAVKGDAAEVERC-LARRSGDLDA 62
Query: 69 RDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDA 128
D + RTALH AC +GH +VVT LV+RKCQ++V D E RTPL++A+ C+ EACA IL++
Sbjct: 63 LDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEH 122
Query: 129 GADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTV 188
GA+ N D+YGNTALHYAVYSE+ + LLS+GA IE +K + TPLL AI + ++ V
Sbjct: 123 GANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMV 182
Query: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248
EFLL + A+++A + + +ALMLA+ S IV +LL+QN+DVFA+D+ G AE YA +
Sbjct: 183 EFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISH 242
Query: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEA 306
+ I QQ+LEH +K+ K E + G+ DE+A E D+ + +K + A
Sbjct: 243 HLTKIQQQILEHKKKILKK------EKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVA 296
Query: 307 ARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEK 366
+ QC+ + S S+ E +I+ E PAK S K + E +
Sbjct: 297 TK---------QCVPEKVSEPLPGSSHEKGNRIVNGQGEGP-----PAKHPSLKPSTEVE 342
Query: 367 ETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTI 426
+ +VK V + L + +A ++ + S E G T
Sbjct: 343 DPAVK----GAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKE------GNNT- 391
Query: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREED 486
++ K++ N+ S +A + T Q+ I K Q FP + K E D
Sbjct: 392 --NKSEKIQLSENICDSTSSAAAGR-------LTQQRKI----GKTYPQQFPKKLKEEHD 438
Query: 487 EEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-K 545
E+ KT V +Y+K NR EEL K +K VE ++ P +
Sbjct: 439 R-----CTLKQENEEKTNV---NMLYKK----NR--EELERKEKQYKKEVEAKQLEPTVQ 484
Query: 546 AFELKNE 552
+ E+K++
Sbjct: 485 SLEMKSK 491
Score = 58.9 bits (141), Expect = 3e-08
Identities = 97/464 (20%), Positives = 178/464 (38%), Gaps = 55/464 (11%)
Query: 744 LPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVES 803
LP ++H+K ++G+ E P K LKP+ ++ A++ K+ +T +AE V S
Sbjct: 309 LPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVAS 368
Query: 804 TFSLFGKPTTENSQ-----------STKVEEDFNLTTKEGATKTVTGQQERDIGIIERAP 852
+E Q S K++ N+ + Q+R IG + P
Sbjct: 369 EEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIG--KTYP 426
Query: 853 QDQTNKMPT--SELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEI--KTTNGKIE- 907
Q K+ K++ + ++ ++ + + E E Y+KE+ K ++
Sbjct: 427 QQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELE-RKEKQYKKEVEAKQLEPTVQS 485
Query: 908 -ESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDN 966
E K + P + N KGL +N L+AD L + + + + +E K
Sbjct: 486 LEMKSKTARNTPNRDFHNHEEMKGLMDEN-CILKADIAILRQEICTMKNDNLEKENKYLK 544
Query: 967 CEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNV 1026
+I + K+ L +E+ + Q E K E + L +E +KR
Sbjct: 545 DIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEA 604
Query: 1027 DI-------------LKEKIRPEEQLRKKLE----VKQQLEQTLRIQDI--ELKSVTSNL 1067
DI E ++ E L+ LE V Q+E + I + E + +T L
Sbjct: 605 DIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQL 664
Query: 1068 NQVSHTHESENDLFHE--NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAE 1125
++ + D F + + + KK +A+ ++ + Q Q +E K E
Sbjct: 665 SETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMK-------------E 711
Query: 1126 LQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKE 1169
+ + K T + + E++ L EN L +L + KE
Sbjct: 712 MYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKE 755
Score = 51.6 bits (122), Expect = 5e-06
Identities = 113/557 (20%), Positives = 205/557 (36%), Gaps = 69/557 (12%)
Query: 503 TQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ 553
T+ C+PE + + + +N + E P K + KP+ E++ A + KN Q
Sbjct: 297 TKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQ 356
Query: 554 TLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVK 613
TLRA Q P S+++ + + + P V T++ E LS + +S
Sbjct: 357 TLRAEQALPVASEEEQERHERSEKKQP-------QVKEGNNTNKSEKIQLSENICDSTSS 409
Query: 614 DGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALE 667
+ T RK+ P K E DR T K E+ +K + + L K +
Sbjct: 410 AAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQ 469
Query: 668 LKDRETLKAESPDNDGL-LKPTCGRKVSLPNKALE-------LKDRETFKAAQMFPSESK 719
K K P L +K R + PN+ L D A + +
Sbjct: 470 YKKEVEAKQLEPTVQSLEMKSKTAR--NTPNRDFHNHEEMKGLMDENCILKADIAILRQE 527
Query: 720 ----QKDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCG 775
+ D+ E + ++ + + + L K E + + L
Sbjct: 528 ICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTR 587
Query: 776 MKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATK 835
+ L LK++E+ K + + +ES S +++S+S K E + L + T+
Sbjct: 588 LNAEL------LKEKESKKRLE-ADIESYQSRLAAAISKHSESVKTERNLKLALER--TR 638
Query: 836 TVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATY 895
V+ Q E I + N+ T +L + + + D+ + L T
Sbjct: 639 DVSVQVEMSSAI---SKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETV 695
Query: 896 QKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPS 955
Q ++ T + +E E + E ++ NS + L+ ++ L + LD +
Sbjct: 696 QNDLSQTQQQTQEMKEMYQNAE--AKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV-- 751
Query: 956 CERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLT 1015
K+D+ E +T +Q+ E+ + LE + K E ++ +
Sbjct: 752 -----HQKEDHKEIVTN-----------IQRGFIESGKKDLVLEEKSKKLMNECDHLKES 795
Query: 1016 LNQ-EEEKRRNVDILKE 1031
L Q E EK V +KE
Sbjct: 796 LFQYEREKTEGVVSIKE 812
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 272 bits (696), Expect = 1e-72
Identities = 183/545 (33%), Positives = 297/545 (54%), Gaps = 32/545 (5%)
Query: 869 DTKSTSDSEIISVSDTQNY-----ECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQ 923
D+ SD + ++V+ Q E LP ++++K + NG+ E P K +P+TE++
Sbjct: 283 DSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVE 342
Query: 924 NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR----ELKKDNCEQITAKMEQTKN 979
+ ++ KN QTLRA+ + ER ++K+ N + K++ ++N
Sbjct: 343 DPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSEN 402
Query: 980 KFC-----VLQKELSEAKEIKSQLENQ---KAKWEQELCSVRLTLNQEEEKRRNVDILKE 1031
C L++ ++I Q K K E + C TL QE E++ NV++L +
Sbjct: 403 -ICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLYK 457
Query: 1032 KIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCM 1086
K R E +Q +K++E KQ LE T++ +++ K+ + N H HE L ENC+
Sbjct: 458 KNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCI 516
Query: 1087 LKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYRE 1146
LK +IA+L+ E+ T+K+ + KENKY +DIKI++E NA L+ +KL ++ +T+ A +Y++
Sbjct: 517 LKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQ 576
Query: 1147 QLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHS 1205
+L L AENT L ++L KEK+ K+ LE +IES+ RLA+A+ H +SV + +N +LA
Sbjct: 577 ELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALER 636
Query: 1206 AGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQ 1265
D +Q M+ +S NE L + L E Q K + K D LR+ +L E Q
Sbjct: 637 TRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQ 696
Query: 1266 RDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVN 1325
D +TQ Q ++ + MYQN + V+ T + +E+++ L+ +N WL QQL H+K +
Sbjct: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKED 756
Query: 1326 KSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYF 1382
++ NIQ K L EK++++ N +HLKE + QYE+EK E VSIK+ KYF
Sbjct: 757 HKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYF 816
Query: 1383 SNFLK 1387
K
Sbjct: 817 QTSRK 821
Score = 225 bits (574), Expect = 2e-58
Identities = 183/547 (33%), Positives = 277/547 (50%), Gaps = 63/547 (11%)
Query: 9 GKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNK 68
G G R + + VYT Y I +L KIH AA +G ++E+ + ++ +L+
Sbjct: 5 GFGSRRGQTAQGSIDHVYTGSGY-RIRDSELQKIHRAAVKGDAAEVERC-LARRSGDLDA 62
Query: 69 RDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDA 128
D + RTALH AC +GH +VVT LV+RKCQ++V D E RTPL++A+ C+ EACA IL++
Sbjct: 63 LDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEH 122
Query: 129 GADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTV 188
GA+ N D+YGNTALHYAVYSE+ + LLS+GA IE +K + TPLL AI + ++ V
Sbjct: 123 GANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMV 182
Query: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248
EFLL K A+++A + + +ALMLA+ S IV +LL+QN+DVFA+D+ G AE YA +
Sbjct: 183 EFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISH 242
Query: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEA 306
+ I QQ+LEH +K+ K E + G+ DE+A E D+ + +K + A
Sbjct: 243 HLTKIQQQILEHKKKILKK------EKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVA 296
Query: 307 ARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEK 366
+ QC+ + S S+ E +I+ E PAK S K + E +
Sbjct: 297 TK---------QCVPEKVSEPLPGSSHEKGNRIVNGQGEGP-----PAKHPSLKPSTEVE 342
Query: 367 ETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTI 426
+ +VK V + L + +A ++ + S E G T
Sbjct: 343 DPAVK----GAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKE------GNNT- 391
Query: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREED 486
++ K++ N+ S +A + T Q+ I K Q FP + K E D
Sbjct: 392 --NKSEKIQLSENICDSTSSAAAGR-------LTQQRKI----GKTYPQQFPKKLKEEHD 438
Query: 487 EEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-K 545
E+ KT V +Y+K NR EEL K +K VE ++ P +
Sbjct: 439 R-----CTLKQENEEKTNV---NMLYKK----NR--EELERKEKQYKKEVEAKQLEPTVQ 484
Query: 546 AFELKNE 552
+ E+K++
Sbjct: 485 SLEMKSK 491
Score = 52.4 bits (124), Expect = 3e-06
Identities = 113/569 (19%), Positives = 220/569 (38%), Gaps = 87/569 (15%)
Query: 503 TQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ 553
T+ C+PE + + + +N + E P K + KP+ E++ A + KN Q
Sbjct: 297 TKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQ 356
Query: 554 TLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVK 613
TLRA Q P S+++ + + + P V T++ E LS + +S
Sbjct: 357 TLRAEQALPVASEEEQERHERSEKKQP-------QVKEGNNTNKSEKIQLSENICDSTSS 409
Query: 614 DGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALE 667
+ T RK+ P K E DR T K E+ +K + L
Sbjct: 410 AAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLY 456
Query: 668 LKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENS 727
K+RE L+ RK K +E K E Q +SK + N
Sbjct: 457 KKNREELE---------------RKEKQYKKEVEAKQLE--PTVQSLEMKSKTARNTPN- 498
Query: 728 WDFESFLETL-LQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMK-ISLPNKAL 785
WDF + E L ++ C+ KA D L + C MK +L +
Sbjct: 499 WDFHNHEEMKGLMDENCILKA-----------------DIAILRQEICTMKNDNLEKENK 541
Query: 786 ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDI 845
LKD + K E +++E L + TE + + +++ N E +E++
Sbjct: 542 YLKDIKIVK-ETNAALEKYIKLNEEMITET--AFRYQQELNDLKAENTRLNAELLKEKES 598
Query: 846 GIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGK 905
A + + + + ++ T + +++ T+ + + Q E+ + K
Sbjct: 599 KKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTR------DVSVQVEMSSAISK 652
Query: 906 IEESPEKPSHFEPATEMQ-NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKK 964
++ E + T+++ N++ +K K + +LR S L + + L ++ + K
Sbjct: 653 VKAENEFLTEQLSETQIKFNALKDKFR--KTRDSLRKKSLALETVQNDLSQTQQQTQEMK 710
Query: 965 DNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRR 1024
+ + AK+ + K+ +++ + + + L Q Q+ + N + R
Sbjct: 711 EMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ---RG 767
Query: 1025 NVDILKEKIRPEEQLRKKLEVKQQLEQTL 1053
++ K+ + EE+ +K + L+++L
Sbjct: 768 FIESGKKDLVLEEKSKKLMNECDHLKESL 796
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 270 bits (689), Expect = 9e-72
Identities = 182/546 (33%), Positives = 298/546 (54%), Gaps = 32/546 (5%)
Query: 869 DTKSTSDSEIISVSDTQNY-----ECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQ 923
D+ SD + ++V+ Q E LP ++++K + NG+ E P K +P+TE++
Sbjct: 283 DSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVE 342
Query: 924 NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR----ELKKDNCEQITAKMEQTKN 979
+ ++ KN QTLRA+ + ER ++K+ N + K++ ++N
Sbjct: 343 DPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSEN 402
Query: 980 KFC-----VLQKELSEAKEIKSQLENQ---KAKWEQELCSVRLTLNQEEEKRRNVDILKE 1031
C L++ ++I Q K K E + C TL QE E++ NV++L +
Sbjct: 403 -ICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLYK 457
Query: 1032 KIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCM 1086
K R E +Q +K++E KQ LE T++ +++ K+ + N H HE L ENC+
Sbjct: 458 KNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCI 516
Query: 1087 LKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYRE 1146
LK +IA+L+ E+ T+K+ + KENKY +DIKI++E NA L+ +KL ++ +T+ A +Y++
Sbjct: 517 LKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQ 576
Query: 1147 QLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHS 1205
+L L AENT L ++L KEK+ K+ LE +IES+ RLA+A+ H +SV + +N +LA
Sbjct: 577 ELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALER 636
Query: 1206 AGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQ 1265
D +Q M+ +S NE L + L E Q K + K D LR+ +L E Q
Sbjct: 637 TQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQ 696
Query: 1266 RDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVN 1325
+ +TQ Q ++ + MYQN + V+ T + +E+++ L+ +N WL QQL H+K +
Sbjct: 697 NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKED 756
Query: 1326 KSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYF 1382
++ NIQ K L EK++++ N +HLKE + QYE+EK E VSIK+ KYF
Sbjct: 757 HKEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYF 816
Query: 1383 SNFLKE 1388
K+
Sbjct: 817 QTSRKK 822
Score = 225 bits (573), Expect = 3e-58
Identities = 183/547 (33%), Positives = 276/547 (50%), Gaps = 63/547 (11%)
Query: 9 GKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNK 68
G G R + + VYT Y I +L KIH AA +G ++E+ + ++ L+
Sbjct: 5 GFGSRRGQTAQGSIDHVYTGSGY-RIRDSELQKIHRAAVKGDAAEVERC-LARRSGELDA 62
Query: 69 RDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDA 128
D + RTALH AC +GH +VVT LV+RKCQ++V D E RTPL++A+ C+ EACA IL++
Sbjct: 63 LDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEH 122
Query: 129 GADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTV 188
GA+ N D+YGNTALHYAVYSE+ + LLS+GA IE +K + TPLL AI + ++ V
Sbjct: 123 GANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMV 182
Query: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248
EFLL K A+++A + + +ALMLA+ S IV +LL+QN+DVFA+D+ G AE YA +
Sbjct: 183 EFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISH 242
Query: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEA 306
+ I QQ+LEH +K+ K E + G+ DE+A E D+ + +K + A
Sbjct: 243 HLTKIQQQILEHKKKILKK------EKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVA 296
Query: 307 ARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEK 366
+ QC+ + S S+ E +I+ E PAK S K + E +
Sbjct: 297 TK---------QCVPEKVSEPLPGSSHEKGNRIVNGQGEGP-----PAKHPSLKPSTEVE 342
Query: 367 ETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTI 426
+ +VK V + L + +A ++ + S E G T
Sbjct: 343 DPAVK----GAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVKE------GNNT- 391
Query: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREED 486
++ K++ N+ S +A + T Q+ I K Q FP + K E D
Sbjct: 392 --NKSEKIQLSENICDSTSSAAAGR-------LTQQRKI----GKTYPQQFPKKLKEEHD 438
Query: 487 EEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-K 545
E+ KT V +Y+K NR EEL K +K VE ++ P +
Sbjct: 439 R-----CTLKQENEEKTNV---NMLYKK----NR--EELERKEKQYKKEVEAKQLEPTVQ 484
Query: 546 AFELKNE 552
+ E+K++
Sbjct: 485 SLEMKSK 491
Score = 54.3 bits (129), Expect = 8e-07
Identities = 117/596 (19%), Positives = 228/596 (38%), Gaps = 87/596 (14%)
Query: 503 TQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ 553
T+ C+PE + + + +N + E P K + KP+ E++ A + KN Q
Sbjct: 297 TKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQ 356
Query: 554 TLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVK 613
TLRA Q P S+++ + + P V T++ E LS + +S
Sbjct: 357 TLRAEQALPVASEEEQQRHERSEKKQP-------QVKEGNNTNKSEKIQLSENICDSTSS 409
Query: 614 DGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALE 667
+ T RK+ P K E DR T K E+ +K + L
Sbjct: 410 AAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLY 456
Query: 668 LKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENS 727
K+RE L+ RK K +E K E Q +SK + N
Sbjct: 457 KKNREELE---------------RKEKQYKKEVEAKQLE--PTVQSLEMKSKTARNTPN- 498
Query: 728 WDFESFLETL-LQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMK-ISLPNKAL 785
WDF + E L ++ C+ KA D L + C MK +L +
Sbjct: 499 WDFHNHEEMKGLMDENCILKA-----------------DIAILRQEICTMKNDNLEKENK 541
Query: 786 ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDI 845
LKD + K E +++E L + TE + + +++ N E +E++
Sbjct: 542 YLKDIKIVK-ETNAALEKYIKLNEEMITET--AFRYQQELNDLKAENTRLNAELLKEKES 598
Query: 846 GIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGK 905
A + + + + ++ T + +++ TQ + + Q E+ + K
Sbjct: 599 KKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQ------DVSVQVEMSSAISK 652
Query: 906 IEESPEKPSHFEPATEMQ-NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKK 964
+++ E + T+++ N++ +K K + +LR S L + + L ++ + K
Sbjct: 653 VKDENEFLTEQLSETQIKFNALKDKFR--KTRDSLRKKSLALETVQNNLSQTQQQTQEMK 710
Query: 965 DNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRR 1024
+ + AK+ + K+ +++ + + + L Q Q+ + N + R
Sbjct: 711 EMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ---RG 767
Query: 1025 NVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDL 1080
++ K+ EE+ +K + L+++L + E V ++ + + S +
Sbjct: 768 FIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
>gi|239756223 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 268 bits (684), Expect = 4e-71
Identities = 142/233 (60%), Positives = 162/233 (69%), Gaps = 46/233 (19%)
Query: 73 KRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADL 132
++TALHW C NGHAEVVT LVDRKCQL++LDGE RTPLMKA QC+RE CANILID+GAD
Sbjct: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
Query: 133 NYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLL 192
N VDVYGNTA+HYA+Y ENL +VA LLS GA IEV+NKA TPLLLAI+KRS+Q VEFLL
Sbjct: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
Query: 193 TKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNY 252
TKN NANA ++ KC
Sbjct: 204 TKNTNANAVDKFKC---------------------------------------------- 217
Query: 253 IHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDE 305
IHQQLLE+ +K+ KN QN+NPEGTS GTPDEAAPL ERTPD AESL+E+TPDE
Sbjct: 218 IHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
Score = 34.3 bits (77), Expect = 0.86
Identities = 19/69 (27%), Positives = 32/69 (46%)
Query: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
D+ TA+H+A + VV L+ + V + G TPL+ A++ E L+
Sbjct: 147 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKN 206
Query: 130 ADLNYVDVY 138
+ N VD +
Sbjct: 207 TNANAVDKF 215
>gi|239745040 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 268 bits (684), Expect = 4e-71
Identities = 142/233 (60%), Positives = 162/233 (69%), Gaps = 46/233 (19%)
Query: 73 KRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADL 132
++TALHW C NGHAEVVT LVDRKCQL++LDGE RTPLMKA QC+RE CANILID+GAD
Sbjct: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
Query: 133 NYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLL 192
N VDVYGNTA+HYA+Y ENL +VA LLS GA IEV+NKA TPLLLAI+KRS+Q VEFLL
Sbjct: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
Query: 193 TKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNY 252
TKN NANA ++ KC
Sbjct: 204 TKNTNANAVDKFKC---------------------------------------------- 217
Query: 253 IHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDE 305
IHQQLLE+ +K+ KN QN+NPEGTS GTPDEAAPL ERTPD AESL+E+TPDE
Sbjct: 218 IHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
Score = 34.3 bits (77), Expect = 0.86
Identities = 19/69 (27%), Positives = 32/69 (46%)
Query: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
D+ TA+H+A + VV L+ + V + G TPL+ A++ E L+
Sbjct: 147 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKN 206
Query: 130 ADLNYVDVY 138
+ N VD +
Sbjct: 207 TNANAVDKF 215
>gi|169209369 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383090 [Homo sapiens]
Length = 193
Score = 266 bits (681), Expect = 8e-71
Identities = 142/231 (61%), Positives = 160/231 (69%), Gaps = 46/231 (19%)
Query: 75 TALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNY 134
TALHW C NGHAEVVT LVDRKCQL++LDGE RTPLMKA QC+RE CANILID+GAD N
Sbjct: 9 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 68
Query: 135 VDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTK 194
VDVYGNTA+HYA+Y ENL +VA LLS GA IEV+NKA TPLLLAI+KRS+Q VEFLLTK
Sbjct: 69 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 128
Query: 195 NANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIH 254
N NANA ++ KC IH
Sbjct: 129 NTNANAVDKFKC----------------------------------------------IH 142
Query: 255 QQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDE 305
QQLLE+ +K+ KN QN+NPEGTS GTPDEAAPL ERTPD AESL+E+TPDE
Sbjct: 143 QQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 193
Score = 34.3 bits (77), Expect = 0.86
Identities = 19/69 (27%), Positives = 32/69 (46%)
Query: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
D+ TA+H+A + VV L+ + V + G TPL+ A++ E L+
Sbjct: 70 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKN 129
Query: 130 ADLNYVDVY 138
+ N VD +
Sbjct: 130 TNANAVDKF 138
>gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 671
Score = 241 bits (614), Expect = 5e-63
Identities = 119/145 (82%), Positives = 127/145 (87%)
Query: 264 LPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDEAARLVEGTSAKIQCLGKA 323
L ++ PEGTS GTPDEAAPLAERTPD AESL+EK PDEAA LVEGT+ KIQCLGKA
Sbjct: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKA 581
Query: 324 TSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTPNKT 383
TSGKFEQS EETP+KI+R KETSEKF+WPAKER RKITWEEKETSVKTECVAGV PNKT
Sbjct: 582 TSGKFEQSAEETPKKIMRTAKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKT 641
Query: 384 EVLEKGTSNMIACPTKETSTKASTN 408
EVLEKGTS M+ CPTKETSTKASTN
Sbjct: 642 EVLEKGTSEMLTCPTKETSTKASTN 666
>gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 671
Score = 239 bits (610), Expect = 1e-62
Identities = 118/145 (81%), Positives = 127/145 (87%)
Query: 264 LPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDEAARLVEGTSAKIQCLGKA 323
L ++ PEGTS GTPDEAAPLAERTPD AESL+EK PDEAA LVEGT+ KIQCLGKA
Sbjct: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKA 581
Query: 324 TSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTPNKT 383
TSGKFEQS EETP+KI+R KETS+KF+WPAKER RKITWEEKETSVKTECVAGV PNKT
Sbjct: 582 TSGKFEQSAEETPKKIMRTAKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKT 641
Query: 384 EVLEKGTSNMIACPTKETSTKASTN 408
EVLEKGTS M+ CPTKETSTKASTN
Sbjct: 642 EVLEKGTSEMLTCPTKETSTKASTN 666
>gi|169194585 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 366
Score = 236 bits (603), Expect = 9e-62
Identities = 125/195 (64%), Positives = 147/195 (75%), Gaps = 3/195 (1%)
Query: 75 TALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNY 134
TALH ACVN H EV+T L DRKC+L+V D E RTPLMKALQC REACANIL+D+G N
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 135 VDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTK 194
VDVYGN ALHYAVYSENL +VA LLS GA IEV+NKA LTPLLL I KRS++ VEFL+TK
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 195 NANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIH 254
NA+ANA ++ KCTALMLA+C GS E V +LLQQ++D+ AED+ G+TA YA A N
Sbjct: 147 NASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFN--- 203
Query: 255 QQLLEHIRKLPKNPQ 269
L R LP+ +
Sbjct: 204 PSLPSQGRSLPREAE 218
Score = 41.2 bits (95), Expect = 0.007
Identities = 32/114 (28%), Positives = 49/114 (42%)
Query: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
D+ ALH+A + + VV L+ R + V + TPL+ + E L+
Sbjct: 88 DVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTKN 147
Query: 130 ADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKR 183
A N VD + TAL AV +L V+ LL I ++ +T A+ R
Sbjct: 148 ASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASR 201
>gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 366
Score = 236 bits (603), Expect = 9e-62
Identities = 125/195 (64%), Positives = 147/195 (75%), Gaps = 3/195 (1%)
Query: 75 TALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNY 134
TALH ACVN H EV+T L DRKC+L+V D E RTPLMKALQC REACANIL+D+G N
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 135 VDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTK 194
VDVYGN ALHYAVYSENL +VA LLS GA IEV+NKA LTPLLL I KRS++ VEFL+TK
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 195 NANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIH 254
NA+ANA ++ KCTALMLA+C GS E V +LLQQ++D+ AED+ G+TA YA A N
Sbjct: 147 NASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFN--- 203
Query: 255 QQLLEHIRKLPKNPQ 269
L R LP+ +
Sbjct: 204 PSLPSQGRSLPREAE 218
Score = 41.2 bits (95), Expect = 0.007
Identities = 32/114 (28%), Positives = 49/114 (42%)
Query: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
D+ ALH+A + + VV L+ R + V + TPL+ + E L+
Sbjct: 88 DVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTKN 147
Query: 130 ADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKR 183
A N VD + TAL AV +L V+ LL I ++ +T A+ R
Sbjct: 148 ASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASR 201
>gi|169192125 PREDICTED: similar to UNCoordinated family member
(unc-44) [Homo sapiens]
Length = 393
Score = 231 bits (588), Expect = 5e-60
Identities = 119/177 (67%), Positives = 140/177 (79%)
Query: 75 TALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNY 134
TALH ACVN H EV+T L DRKC+L+V D E RTPLMKALQC REA ANIL+D+G N
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREAYANILVDSGPSPNI 86
Query: 135 VDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTK 194
VDVYGN ALHYAVYSENL +VA LLS GA I+V+NKA LTPLLL I KRS++ VEFL+TK
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIQVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 195 NANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVN 251
NA+ANA ++ KCTALMLA+C GS E V +LLQQ++D+ AED+ G+TA YA A N
Sbjct: 147 NASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFN 203
Score = 42.4 bits (98), Expect = 0.003
Identities = 36/131 (27%), Positives = 54/131 (41%)
Query: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
D+ ALH+A + + VV L+ R + V + TPL+ + E L+
Sbjct: 88 DVYGNMALHYAVYSENLSVVAKLLSRGADIQVKNKACLTPLLLVITKRSEEIVEFLVTKN 147
Query: 130 ADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVE 189
A N VD + TAL AV +L V+ LL I ++ +T A+ R
Sbjct: 148 ASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFNPNTL 207
Query: 190 FLLTKNANANA 200
L T A +A
Sbjct: 208 SLSTGTAPEDA 218
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 230 bits (586), Expect = 8e-60
Identities = 126/269 (46%), Positives = 180/269 (66%), Gaps = 3/269 (1%)
Query: 38 DLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKC 97
DLGK+H AA G+V + + + + + P +NKRD KKRTALH AC NG++EVV+ L+DR+C
Sbjct: 65 DLGKLHRAAWWGEVPRADLIVMLRGP-GINKRDKKKRTALHLACANGNSEVVSLLLDRQC 123
Query: 98 QLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVAT 157
QL+V D + RT L+KA+QC+ + CA +L+ G D N D+YGNTALHYAVY+E+ LM T
Sbjct: 124 QLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKT 183
Query: 158 LLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGS 217
LL YGA IE +NK LTPLLLA+ + ++ V+FL+ K AN NA + TAL+LA+ GS
Sbjct: 184 LLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRTALILAVRCGS 243
Query: 218 SEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEH-IRKLPKNPQ-NTNPEG 275
+ IV +LLQQN+DVF++D+ G TAE YA + + I Q L ++ ++P N N+NPE
Sbjct: 244 ASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQMPNNSSGNSNPEQ 303
Query: 276 TSTGTPDEAAPLAERTPDTAESLLEKTPD 304
T +E + + ++ + + PD
Sbjct: 304 DLKLTSEEEPQRLKGSENSQHEKVTQEPD 332
Score = 40.8 bits (94), Expect = 0.009
Identities = 23/45 (51%), Positives = 30/45 (66%)
Query: 942 DSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQK 986
DS +LSKI DA+ S E ELK + EQ+T ++EQ +N VLQK
Sbjct: 454 DSASLSKIQDAVISEEHLLELKNSHYEQLTVEVEQMENMVHVLQK 498
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 225 bits (573), Expect = 3e-58
Identities = 140/382 (36%), Positives = 213/382 (55%), Gaps = 21/382 (5%)
Query: 38 DLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKC 97
DL K+H AA G+V + + + V + ++NKRD +KRTALH A NG++EVV L+DR+C
Sbjct: 139 DLDKLHRAAWWGKVPRKD-LIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRC 197
Query: 98 QLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVAT 157
QLNVLD + RT L+KA+QC+ + C +L++ GAD N D YGNTALHYA+Y+E+ LM
Sbjct: 198 QLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKA 257
Query: 158 LLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGS 217
LL YGA IE +NK LTPLLL + ++ +Q V+FL+ K AN NA + TAL+LA+C GS
Sbjct: 258 LLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGS 317
Query: 218 SEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEHIRK--LPKNPQNTNPEG 275
+ IV +LL+QNVDV ++D+ G TA YA + + I + L ++ K L + +N+NPE
Sbjct: 318 ASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQ 377
Query: 276 TSTGTPDEAAPLAERTPDTAESLLEKTPD---EAARLVEGTSAKI--------------Q 318
T +E + + + ++ + + P+ + R VE K
Sbjct: 378 DLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGA 437
Query: 319 CLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGV 378
G G Q P P E E S + ++++ EE+ T + + +
Sbjct: 438 SAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLS-EEQNTGISQDEILTN 496
Query: 379 TPNKTEVLEKGTSNMIACPTKE 400
+ EV EK ++ ++ K+
Sbjct: 497 KQKQIEVAEKEMNSKLSLSHKK 518
Score = 70.9 bits (172), Expect = 8e-12
Identities = 61/223 (27%), Positives = 111/223 (49%), Gaps = 18/223 (8%)
Query: 932 EWKNKQTLRADSTTLSKILDA-LPSCERGRELK-KDNCEQITAKMEQTKNKFC------V 983
++K KQ L+ S + D L S E + LK +N + E NK C
Sbjct: 359 DYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEE 418
Query: 984 LQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRPEEQ--LRK 1041
++K S + L N + + + +++ E ++ D E+ +EQ +K
Sbjct: 419 IKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQK 478
Query: 1042 KLEVKQQL----EQTLRIQDIELKSVTSNLN-QVSHTHESENDLFHENCMLKKEIAMLKL 1096
+L +Q ++ L + +++ +N ++S +H+ E DL EN ML++EIAML+L
Sbjct: 479 QLSEEQNTGISQDEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRL 538
Query: 1097 EVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTK 1139
E+ KHQ+Q++ENK E+I+ ++EK L ++L ++ +TK
Sbjct: 539 ELDETKHQNQLRENKILEEIESVKEK---LLKAIQLNEEALTK 578
Score = 30.8 bits (68), Expect = 9.5
Identities = 49/272 (18%), Positives = 103/272 (37%), Gaps = 38/272 (13%)
Query: 1116 IKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKEILETEI 1175
+ +L E+N ++ Q + A +Y +++ + ++ L + ++K++L+
Sbjct: 321 VNLLLEQNVDVS-----SQDLSGQTAREY-----AVSSHHHVICELLSDYKEKQMLKISS 370
Query: 1176 ESHHPRLASALQDHDQSVTSRKNQELAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYE 1235
E+ +P + D +TS + + S P + ++ N + EV +
Sbjct: 371 ENSNP-------EQDLKLTSEEESQRLKVSENSQPEKMSQEPEI-NKDCDREVEEEIKKH 422
Query: 1236 AQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTE- 1294
P+ N A ++ L+ + R Q + E + +EQ++ K
Sbjct: 423 GSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSE 482
Query: 1295 -------QQESLEQKLFQLESKNRWLRQQLVYAHKK----------VNKSKVTINIQFPE 1337
Q E L K Q+E + + +L +HKK + + + ++ E
Sbjct: 483 EQNTGISQDEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDE 542
Query: 1338 MKMQRHLNEKN--EEVFNYGNHLKERIDQYEK 1367
K Q L E EE+ + L + I E+
Sbjct: 543 TKHQNQLRENKILEEIESVKEKLLKAIQLNEE 574
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,340,965
Number of Sequences: 37866
Number of extensions: 2373860
Number of successful extensions: 16736
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 429
Number of HSP's successfully gapped in prelim test: 920
Number of HSP's that attempted gapping in prelim test: 8691
Number of HSP's gapped (non-prelim): 5223
length of query: 1392
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1277
effective length of database: 13,892,928
effective search space: 17741269056
effective search space used: 17741269056
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.