BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] (377 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] 817 0.0 gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 631 0.0 gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 626 e-180 gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 626 e-180 gi|40353769 chordin-like 2 [Homo sapiens] 157 1e-38 gi|30089980 chordin [Homo sapiens] 78 1e-14 gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 70 4e-12 gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 69 9e-12 gi|38348414 von Willebrand factor C domain containing 2 [Homo sa... 60 4e-09 gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 59 5e-09 gi|37693519 BMP-binding endothelial regulator precursor protein ... 59 9e-09 gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 55 8e-08 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 44 2e-04 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 44 2e-04 gi|122937446 von Willebrand factor C domain-containing protein 2... 44 2e-04 gi|40317626 thrombospondin 1 precursor [Homo sapiens] 44 3e-04 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 44 3e-04 gi|40317628 thrombospondin 2 precursor [Homo sapiens] 44 3e-04 gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 44 3e-04 gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 44 3e-04 gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 44 3e-04 gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 44 3e-04 gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 44 3e-04 gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 43 4e-04 gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 43 4e-04 gi|108773804 Fraser syndrome 1 [Homo sapiens] 43 4e-04 gi|109150416 peroxidasin [Homo sapiens] 40 0.004 gi|126517478 peroxidasin homolog-like [Homo sapiens] 39 0.008 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 38 0.013 gi|188497705 BRCA1 associated protein [Homo sapiens] 35 0.11 >gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] Length = 377 Score = 817 bits (2111), Expect = 0.0 Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120 Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV Sbjct: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180 Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC Sbjct: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 Query: 241 KVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300 KVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW Sbjct: 241 KVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300 Query: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL Sbjct: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360 Query: 361 EDLVKVLYLERSEKGHC 377 EDLVKVLYLERSEKGHC Sbjct: 361 EDLVKVLYLERSEKGHC 377 >gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] Length = 456 Score = 631 bits (1627), Expect = 0.0 Identities = 295/316 (93%), Positives = 297/316 (93%), Gaps = 1/316 (0%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121 C C CSE GNV C CP + C PV +P CC C GDGELSWEHSDGDIFRQPANR Sbjct: 142 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 200 Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC Sbjct: 201 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 260 Query: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK Sbjct: 261 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 320 Query: 242 VCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWT 301 VCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWT Sbjct: 321 VCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWT 380 Query: 302 IRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELE 361 IRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELE Sbjct: 381 IRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELE 440 Query: 362 DLVKVLYLERSEKGHC 377 DLVKVLYLERSEKGHC Sbjct: 441 DLVKVLYLERSEKGHC 456 Score = 236 bits (602), Expect = 3e-62 Identities = 125/245 (51%), Positives = 140/245 (57%), Gaps = 65/245 (26%) Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP P N Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDS-------------LPPVN 107 Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180 + S + +GT Q HG++ Sbjct: 108 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 127 Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 V+ G ++ PN +C C+C+ C CP + C +P + CC Sbjct: 128 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 175 Query: 241 KVCPG 245 +VC G Sbjct: 176 RVCRG 180 Score = 60.1 bits (144), Expect = 3e-09 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89 KH + C+ K Y GE WHP L +G+V CV C C+ C ++ CPN + C P Sbjct: 255 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 312 Query: 90 HIPHLCCPRCPG 101 I CC CPG Sbjct: 313 KIDGKCCKVCPG 324 >gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] Length = 457 Score = 626 bits (1615), Expect = e-180 Identities = 295/317 (93%), Positives = 297/317 (93%), Gaps = 2/317 (0%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121 C C CSE GNV C CP + C PV +P CC C GDGELSWEHSDGDIFRQPANR Sbjct: 142 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 200 Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC Sbjct: 201 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 260 Query: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK Sbjct: 261 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 320 Query: 242 VCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300 VCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW Sbjct: 321 VCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 380 Query: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL Sbjct: 381 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 440 Query: 361 EDLVKVLYLERSEKGHC 377 EDLVKVLYLERSEKGHC Sbjct: 441 EDLVKVLYLERSEKGHC 457 Score = 236 bits (602), Expect = 3e-62 Identities = 125/245 (51%), Positives = 140/245 (57%), Gaps = 65/245 (26%) Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP P N Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDS-------------LPPVN 107 Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180 + S + +GT Q HG++ Sbjct: 108 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 127 Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 V+ G ++ PN +C C+C+ C CP + C +P + CC Sbjct: 128 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 175 Query: 241 KVCPG 245 +VC G Sbjct: 176 RVCRG 180 Score = 60.1 bits (144), Expect = 3e-09 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89 KH + C+ K Y GE WHP L +G+V CV C C+ C ++ CPN + C P Sbjct: 255 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 312 Query: 90 HIPHLCCPRCPG 101 I CC CPG Sbjct: 313 KIDGKCCKVCPG 324 >gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] Length = 458 Score = 626 bits (1615), Expect = e-180 Identities = 295/317 (93%), Positives = 297/317 (93%), Gaps = 2/317 (0%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121 C C CSE GNV C CP + C PV +P CC C GDGELSWEHSDGDIFRQPANR Sbjct: 143 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 201 Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC Sbjct: 202 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 261 Query: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK Sbjct: 262 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 321 Query: 242 VCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300 VCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW Sbjct: 322 VCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 381 Query: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL Sbjct: 382 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 441 Query: 361 EDLVKVLYLERSEKGHC 377 EDLVKVLYLERSEKGHC Sbjct: 442 EDLVKVLYLERSEKGHC 458 Score = 238 bits (608), Expect = 5e-63 Identities = 126/245 (51%), Positives = 141/245 (57%), Gaps = 64/245 (26%) Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60 Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP D P N Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDS------------LPPVN 108 Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180 + S + +GT Q HG++ Sbjct: 109 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 128 Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 V+ G ++ PN +C C+C+ C CP + C +P + CC Sbjct: 129 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 176 Query: 241 KVCPG 245 +VC G Sbjct: 177 RVCRG 181 Score = 60.1 bits (144), Expect = 3e-09 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89 KH + C+ K Y GE WHP L +G+V CV C C+ C ++ CPN + C P Sbjct: 256 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 313 Query: 90 HIPHLCCPRCPG 101 I CC CPG Sbjct: 314 KIDGKCCKVCPG 325 >gi|40353769 chordin-like 2 [Homo sapiens] Length = 451 Score = 157 bits (397), Expect = 1e-38 Identities = 86/252 (34%), Positives = 122/252 (48%), Gaps = 25/252 (9%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121 CV C C+E G + C CP C +P+ +P CC C + E SD + Sbjct: 138 CVLCSCTE-GQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEAS---EQSDEE-------- 185 Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMD---------SQQASGTIVQIVIN 172 ++ S H + P G R PG + G + A T V+IV+ Sbjct: 186 DSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLK 245 Query: 173 NKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 232 KHK + CV GKTYSHGE WHP RAFG + C+LCTC +Q+C+++ CP YPC++P Sbjct: 246 EKHK--KACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHP 303 Query: 233 QKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERP 292 +K+ GKCCK+CP KA PG S + + + + R+ ALE E Sbjct: 304 EKVAGKCCKICPEDKAD--PGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEAS 361 Query: 293 PQVEVHVWTIRK 304 VE+++W + K Sbjct: 362 DLVEIYLWKLVK 373 Score = 99.4 bits (246), Expect = 5e-21 Identities = 60/217 (27%), Positives = 86/217 (39%), Gaps = 65/217 (29%) Query: 34 ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH 93 + +C+F K+Y GE WHPYLEP GL+YC+ C CSE +V C R+ CP VHC PV P Sbjct: 30 DMFCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQ 89 Query: 94 LCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 153 CCP+C +P GL P + H Sbjct: 90 QCCPKC--------------------------------VEP---HTPSGLRAPPKSCQHN 114 Query: 154 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 213 G + ++HG++ + S PN +CVLC+C Sbjct: 115 GTM------------------YQHGEIF----SAHELFPSRLPN-------QCVLCSCTE 145 Query: 214 TKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE 250 + C CP C P + CC+ C + +++ Sbjct: 146 GQIYCGLTTCPEP-GCPAPLPLPDSCCQACKDEASEQ 181 Score = 55.8 bits (133), Expect = 6e-08 Identities = 28/73 (38%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89 KH + C+ K Y GE WHP +G + C+ C C E+G C RV CP + C P Sbjct: 247 KHKKA-CVHGGKTYSHGEVWHPAFRAFGPLPCILCTC-EDGRQDCQRVTCPTEYPCRHPE 304 Query: 90 HIPHLCCPRCPGD 102 + CC CP D Sbjct: 305 KVAGKCCKICPED 317 >gi|30089980 chordin [Homo sapiens] Length = 955 Score = 78.2 bits (191), Expect = 1e-14 Identities = 57/211 (27%), Positives = 75/211 (35%), Gaps = 67/211 (31%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C F+ ++ G RW P +P C C C V+C V CP C PV P CC Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156 P CP ++ R P SR G F G RS R A Sbjct: 760 PVCPEKQDV-----------------------RDLPGLPRSRDPGEGCYFDGDRSWRAA- 795 Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--NVT 214 G WHP + FG+++C +CTC Sbjct: 796 ----------------------------------GTRWHPVVPPFGLIKCAVCTCKGGTG 821 Query: 215 KQECKKIHCPNRYPCKYPQKID-GKCCKVCP 244 + C+K+ CP R C P +++ CCK CP Sbjct: 822 EVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851 Score = 62.0 bits (149), Expect = 8e-10 Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 14/118 (11%) Query: 37 CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84 C F K Y + E WHP L EP+G++ CV C C G V C ++ CP Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110 Query: 85 CLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 142 C P +P CC CP + S G F P R+ H + +P +A G Sbjct: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166 Score = 58.9 bits (141), Expect = 7e-09 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 17/93 (18%) Query: 181 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 227 C GK Y+ E+WHP+L FG++ CVLC C + CK I CP Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109 Query: 228 PCKYPQKIDGKCCKVCPGKKA---KELPGQSFD 257 C P+++ G CC+ CP +++ ++ G SF+ Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFE 142 Score = 50.1 bits (118), Expect = 3e-06 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 6/74 (8%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 C G+ HG W PN C LCTC C + CP C +P + +CC Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759 Query: 241 KVCPGKK-AKELPG 253 VCP K+ ++LPG Sbjct: 760 PVCPEKQDVRDLPG 773 Score = 35.8 bits (81), Expect = 0.065 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 4/64 (6%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95 C F + + + WHP + P+G + C+ C C G C R C + C S C Sbjct: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928 Query: 96 CPRC 99 C RC Sbjct: 929 CSRC 932 >gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] Length = 1503 Score = 69.7 bits (169), Expect = 4e-12 Identities = 63/221 (28%), Positives = 79/221 (35%), Gaps = 41/221 (18%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C + + Y G+ + P C C C ++G V CS V CP C P P CC Sbjct: 425 CTYHSQVYANGQNFTDADSP-----CHACHC-QDGTVTCSLVDCPPTTCARPQSGPGQCC 478 Query: 97 PRCPGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 153 PRCP D L E DG+ F P + +E R +H P P +A PG Sbjct: 479 PRCP-DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGT---- 533 Query: 154 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW-HPNLRAFGIVECVLCTCN 212 SG C GK Y G + HP+ C LC C Sbjct: 534 ---CCPNDCSG----------------CAFGGKEYPSGADFPHPS------DPCRLCRCL 568 Query: 213 VTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPG 253 +C C PC P + G+CC CP PG Sbjct: 569 SGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAPAGCPRPG 608 Score = 64.7 bits (156), Expect = 1e-10 Identities = 55/208 (26%), Positives = 83/208 (39%), Gaps = 38/208 (18%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95 C +++R GE P G C +C C+ NG+V C + CP V C P IP C Sbjct: 252 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 303 Query: 96 CPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGA 155 CP C G ++ + FR + R R S QAG +S Sbjct: 304 CPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS----------- 342 Query: 156 LMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTK 215 + Q+ T + + + + C +G+ ++ G W P+ R C C C Sbjct: 343 -CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PCTACVCQDGV 395 Query: 216 QECKKIHCPNRYPCKYPQKIDGKCCKVC 243 +C + CP PC++P + G CC C Sbjct: 396 PKCGAVLCPPA-PCQHPTQPPGACCPSC 422 Score = 61.2 bits (147), Expect = 1e-09 Identities = 55/212 (25%), Positives = 76/212 (35%), Gaps = 43/212 (20%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C + Y GE + P C C C G V C C ++CL P CC Sbjct: 138 CSQNGQTYGNGETFSPDA-------CTTCRCL-TGAVQCQGPSCSELNCLESCTPPGECC 189 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156 P C +G WEH G + P + R + R+ L +P Sbjct: 190 PICCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQCRQRECASLCPYP--------- 237 Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE---SWHPNLRAFGIVECVLCTCNV 213 ++ GT + C NG+ + GE S P C C C Sbjct: 238 --ARPLPGTCCPVCDG--------CFLNGREHRSGEPVGSGDP---------CSHCRCAN 278 Query: 214 TKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245 +C+ + CP PC++P KI G+CC VC G Sbjct: 279 GSVQCEPLPCPP-VPCRHPGKIPGQCCPVCDG 309 Score = 53.5 bits (127), Expect = 3e-07 Identities = 56/222 (25%), Positives = 79/222 (35%), Gaps = 58/222 (26%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C F K+Y G + +P L C++ GNV C RC + C PV +P CC Sbjct: 542 CAFGGKEYPSGADFPHPSDPCRLCRCLS------GNVQCLARRCVPLPCPEPVLLPGECC 595 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP--PSRQA----GGLS------ 144 P+CP +P A H+ H+ ++ PP P R+ G +S Sbjct: 596 PQCPAPAGCP----------RPG---AAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642 Query: 145 -RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGI 203 P A +G S C+ GK ++ GE + A Sbjct: 643 PPAPCAHPRQGPCCPSCDG------------------CLYQGKEFASGERFPSPTAA--- 681 Query: 204 VECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245 C LC C C+ C C +P + G CC C G Sbjct: 682 --CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCDG 718 Score = 48.9 bits (115), Expect = 7e-06 Identities = 62/232 (26%), Positives = 88/232 (37%), Gaps = 38/232 (16%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C +Q +Y+ E + L+ GL CV C C + G V C CP C P LC Sbjct: 310 CEYQGHQYQSQETFR--LQERGL--CVRCSC-QAGEVSCEEQECPVTPCALPASGRQLC- 363 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156 P C DGE E ++G + +P R + D P + G + P H Sbjct: 364 PACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP--KCGAVLCPPAPCQH---- 410 Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQ 216 Q G + + H QV +NG+ ++ +S C C C Sbjct: 411 --PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-----------PCHACHCQDGTV 455 Query: 217 ECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE---LPGQSFDNKGYFCGE 265 C + CP C PQ G+CC CP +E + G+SF + C E Sbjct: 456 TCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 506 Score = 47.4 bits (111), Expect = 2e-05 Identities = 52/218 (23%), Positives = 77/218 (35%), Gaps = 46/218 (21%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C+ Q ++++ GE + P G C C C + G V C R++CP + C V CC Sbjct: 837 CLSQGREHQDGEEFEG---PAGS--CEWCRC-QAGQVSCVRLQCPPLPCKLQVTERGSCC 890 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156 PRC G EH +G S + PP S + + H G + Sbjct: 891 PRCRGCLAHGEEHPEG-----------------SRWVPPDSACSSCV-------CHEGVV 926 Query: 157 MDSQQASGTIVQIVINNKH---KHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 213 ++ + H C G+ Y GES+ P G C +C C Sbjct: 927 TCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQP-----GADPCEVCICEP 981 Query: 214 TKQ-----ECKKIHCPNRYPCKYPQKI---DGKCCKVC 243 + C + CP+ C Q + CC C Sbjct: 982 QPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC 1019 Score = 46.2 bits (108), Expect = 5e-05 Identities = 59/240 (24%), Positives = 76/240 (31%), Gaps = 57/240 (23%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C++Q K++ GER+ P C C+C E G+V C C C P CC Sbjct: 662 CLYQGKEFASGERF-----PSPTAACHLCLCWE-GSVSCEPKACAPALCPFPARGD--CC 713 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF---------P 147 P C G L + F P P L F P Sbjct: 714 PDCDGCEYLGESYLSNQEFPDPRE---------------PCNLCTCLGGFVTCGRRPCEP 758 Query: 148 GARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECV 207 SH L+ S T Q C +G T + GE+ L C Sbjct: 759 PGCSH--PLIPSGHCCPTC------------QGCRYHGVTTASGETLPDPLDP----TCS 800 Query: 208 LCTCNVTKQECKKIHCPNRYPCKYPQKIDGKC----CKVCPGKKAKELPGQSFDNKGYFC 263 LCTC C+K CP P P G C C C + + G+ F+ C Sbjct: 801 LCTCQEGSMRCQKKPCP---PALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSC 857 Score = 42.0 bits (97), Expect = 0.001 Identities = 49/217 (22%), Positives = 74/217 (34%), Gaps = 37/217 (17%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENG----NVLCSRVRCPNVHCLSPVHI- 91 C + +KY GE + P +P C CIC ++ C R +CP++ P + Sbjct: 954 CEHEGRKYEPGESFQPGADP-----CEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLL 1008 Query: 92 ---PHLCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPG 148 P CCP C E S+G + + A + ++ QA P Sbjct: 1009 PPGPQHCCPTC---AEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPL 1065 Query: 149 ARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVL 208 + H G+ + Q CV G+ + GE W + C Sbjct: 1066 SERHT--------PPGSCCPVC----RAPTQSCVHQGREVASGERW-------TVDTCTS 1106 Query: 209 CTCNVTKQECKKIHCP--NRYPCKYPQKIDGKCCKVC 243 C+C C+ C + P K P G CC C Sbjct: 1107 CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143 Score = 40.8 bits (94), Expect = 0.002 Identities = 46/214 (21%), Positives = 67/214 (31%), Gaps = 42/214 (19%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C + + Y + + EP L C+ G V C R C C P+ CC Sbjct: 719 CEYLGESYLSNQEFPDPREPCNLCTCLG------GFVTCGRRPCEPPGCSHPLIPSGHCC 772 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREA-----RHSYHRSHYDPPPSRQAGGLSRFPGARS 151 P C G + G+ P + + R P P P Sbjct: 773 PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCP----------PALCP 822 Query: 152 HRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC 211 H + G V ++ C+S G+ + GE + + C C C Sbjct: 823 H--------PSPGPCFCPVCHS-------CLSQGREHQDGEEFEGPAGS-----CEWCRC 862 Query: 212 NVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245 + C ++ CP PCK G CC C G Sbjct: 863 QAGQVSCVRLQCP-PLPCKLQVTERGSCCPRCRG 895 Score = 38.1 bits (87), Expect = 0.013 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 8/67 (11%) Query: 177 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 236 H + C NG+TY +GE++ P+ C C C +C+ C + C Sbjct: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLTGAVQCQGPSC-SELNCLESCTPP 185 Query: 237 GKCCKVC 243 G+CC +C Sbjct: 186 GECCPIC 192 >gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] Length = 814 Score = 68.6 bits (166), Expect = 9e-12 Identities = 62/216 (28%), Positives = 78/216 (36%), Gaps = 41/216 (18%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C + + Y G+ + P C C C ++G V CS V CP C P P CC Sbjct: 483 CTYHSQVYANGQNFTDADSP-----CHACHC-QDGTVTCSLVDCPPTTCARPQSGPGQCC 536 Query: 97 PRCPGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 153 PRCP D L E DG+ F P + +E R +H P P +A PG Sbjct: 537 PRCP-DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGT---- 591 Query: 154 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW-HPNLRAFGIVECVLCTCN 212 SG C GK Y G + HP+ C LC C Sbjct: 592 ---CCPNDCSG----------------CAFGGKEYPSGADFPHPS------DPCRLCRCL 626 Query: 213 VTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKA 248 +C C PC P + G+CC CP A Sbjct: 627 SGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPA 661 Score = 66.6 bits (161), Expect = 3e-11 Identities = 57/219 (26%), Positives = 83/219 (37%), Gaps = 43/219 (19%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHI 91 H + C ++ + Y G + P C+ C C + V C ++CP C PV Sbjct: 187 HCKPGCDYEGQLYEEGVTFLSSSNP-----CLQCTCLRS-RVRCMALKCPPSPCPEPVLR 240 Query: 92 PHLCCPRCPG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGA 149 P CCP C G +G WEH G + P + R + R+ L +P Sbjct: 241 PGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQCRQRECASLCPYP-- 295 Query: 150 RSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE---SWHPNLRAFGIVEC 206 ++ GT + C NG+ + GE S P C Sbjct: 296 ---------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVGSGDP---------C 329 Query: 207 VLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245 C C +C+ + CP PC++P KI G+CC VC G Sbjct: 330 SHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367 Score = 64.7 bits (156), Expect = 1e-10 Identities = 55/208 (26%), Positives = 83/208 (39%), Gaps = 38/208 (18%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95 C +++R GE P G C +C C+ NG+V C + CP V C P IP C Sbjct: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361 Query: 96 CPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGA 155 CP C G ++ + FR + R R S QAG +S Sbjct: 362 CPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS----------- 400 Query: 156 LMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTK 215 + Q+ T + + + + C +G+ ++ G W P+ R C C C Sbjct: 401 -CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PCTACVCQDGV 453 Query: 216 QECKKIHCPNRYPCKYPQKIDGKCCKVC 243 +C + CP PC++P + G CC C Sbjct: 454 PKCGAVLCPPA-PCQHPTQPPGACCPSC 480 Score = 53.9 bits (128), Expect = 2e-07 Identities = 56/223 (25%), Positives = 80/223 (35%), Gaps = 55/223 (24%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C F K+Y G + +P L C++ GNV C RC + C PV +P CC Sbjct: 600 CAFGGKEYPSGADFPHPSDPCRLCRCLS------GNVQCLARRCVPLPCPEPVLLPGECC 653 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP--PSRQA----GGLS------ 144 P+CP + G A H+ H+ ++ PP P R+ G +S Sbjct: 654 PQCPAAPAPAGCPRPG----------AAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 703 Query: 145 -RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGI 203 P A +G S C+ GK ++ GE + A Sbjct: 704 PPAPCAHPRQGPCCPSCDG------------------CLYQGKEFASGERFPSPTAA--- 742 Query: 204 VECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGK 246 C LC C C+ C C +P + G CC C G+ Sbjct: 743 --CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCDGE 780 Score = 48.9 bits (115), Expect = 7e-06 Identities = 62/232 (26%), Positives = 88/232 (37%), Gaps = 38/232 (16%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C +Q +Y+ E + L+ GL CV C C + G V C CP C P LC Sbjct: 368 CEYQGHQYQSQETFR--LQERGL--CVRCSC-QAGEVSCEEQECPVTPCALPASGRQLC- 421 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156 P C DGE E ++G + +P R + D P + G + P H Sbjct: 422 PACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP--KCGAVLCPPAPCQH---- 468 Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQ 216 Q G + + H QV +NG+ ++ +S C C C Sbjct: 469 --PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-----------PCHACHCQDGTV 513 Query: 217 ECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE---LPGQSFDNKGYFCGE 265 C + CP C PQ G+CC CP +E + G+SF + C E Sbjct: 514 TCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 564 Score = 45.8 bits (107), Expect = 6e-05 Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 45/213 (21%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C + Y GE + P C C C E G + C++ CP P P CC Sbjct: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPR----GPCPEPGACC 185 Query: 97 PRC-PGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGA 155 P C PG + +G F +N + + RS R Sbjct: 186 PHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRS----------------------RVR 223 Query: 156 LMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 213 M + + V+ H Q C G + HG+ W C +C C Sbjct: 224 CMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW-----TTPGDPCRICRCLE 278 Query: 214 TKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 245 +C++ C + C YP + + G CC VC G Sbjct: 279 GHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 177 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 236 H + C NG+TY +GE++ P+ C C C C + CP R PC P Sbjct: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLEGTITCNQKPCP-RGPCPEP---- 181 Query: 237 GKCCKVCPGKKAKELPGQSFD 257 G CC C K + GQ ++ Sbjct: 182 GACCPHC--KPGCDYEGQLYE 200 Score = 40.0 bits (92), Expect = 0.003 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 8/67 (11%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C++Q K++ GER+ P C C+C E G+V C C C P CC Sbjct: 723 CLYQGKEFASGERF-----PSPTAACHLCLCWE-GSVSCEPKACAPALCPFPARGD--CC 774 Query: 97 PRCPGDG 103 P C G+G Sbjct: 775 PDCDGEG 781 >gi|38348414 von Willebrand factor C domain containing 2 [Homo sapiens] Length = 325 Score = 59.7 bits (143), Expect = 4e-09 Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 7/71 (9%) Query: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88 Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P Sbjct: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262 Query: 89 VHIPHLCCPRC 99 V+ P CCP C Sbjct: 263 VYEPDQCCPIC 273 >gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] Length = 1036 Score = 59.3 bits (142), Expect = 5e-09 Identities = 52/201 (25%), Positives = 72/201 (35%), Gaps = 28/201 (13%) Query: 55 EPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC---PGDGELSWEHS- 110 E + + C C C +G VLC CP + C +P CCP+C P LS +S Sbjct: 691 ETWNIDSCTQCTC-HSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSV 749 Query: 111 -------DGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQAS 163 +GDIF + + D S + P R L Q Sbjct: 750 PNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESC---PSVSCERPVLRKGQCCP 806 Query: 164 GTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHC 223 I + VC +GK Y+ E W + C C C + C + C Sbjct: 807 YCIEDTIPKKV-----VCHFSGKAYADEERWD-------LDSCTHCYCLQGQTLCSTVSC 854 Query: 224 PNRYPCKYPQKIDGKCCKVCP 244 P PC P ++G CC +CP Sbjct: 855 PP-LPCVEPINVEGSCCPMCP 874 Score = 54.7 bits (130), Expect = 1e-07 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 8/64 (12%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C F K Y ERW L C +C C + G LCS V CP + C+ P+++ CC Sbjct: 819 CHFSGKAYADEERWD-------LDSCTHCYCLQ-GQTLCSTVSCPPLPCVEPINVEGSCC 870 Query: 97 PRCP 100 P CP Sbjct: 871 PMCP 874 Score = 42.4 bits (98), Expect = 7e-04 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 9/63 (14%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 C +NG +HG+ W + +C C C ++ C C C P K+ G+CC Sbjct: 403 CYANGLILAHGDRWRED-------DCTFCQCVNGERHCVATVCGQT--CTNPVKVPGECC 453 Query: 241 KVC 243 VC Sbjct: 454 PVC 456 Score = 38.1 bits (87), Expect = 0.013 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGD 102 C C C NG +C+ + CP C +P P CCP C D Sbjct: 626 CRECYCL-NGREMCALITCPVPACGNPTIHPGQCCPSCADD 665 Score = 36.2 bits (82), Expect = 0.050 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 8/59 (13%) Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGD 102 + E W P + C +CIC ++ + C CP+V C PV CCP C D Sbjct: 761 FLAAESWKPDV-------CTSCICIDSV-ISCFSESCPSVSCERPVLRKGQCCPYCIED 811 Score = 34.7 bits (78), Expect = 0.14 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 8/59 (13%) Query: 185 GKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243 G+ + GE+W+ I C CTC+ + C+ CP C+ P + CC C Sbjct: 684 GEYFVEGETWN-------IDSCTQCTCHSGRVLCETEVCPPLL-CQNPSRTQDSCCPQC 734 Score = 30.8 bits (68), Expect = 2.1 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 12/55 (21%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC----------PGDGELS 106 C C C NG C C C +PV +P CCP C P GELS Sbjct: 421 CTFCQCV-NGERHCVATVCGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELS 473 >gi|37693519 BMP-binding endothelial regulator precursor protein [Homo sapiens] Length = 685 Score = 58.5 bits (140), Expect = 9e-09 Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 25/215 (11%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL-- 94 C+F+ +Y+ GE + P C C C+ G C R CP + C P H+ H+ Sbjct: 166 CVFEGVQYQEGEEFQPEGSK-----CTKCSCT-GGRTQCVREVCPILSC--PQHLSHIPP 217 Query: 95 --CCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSH 152 CCP+C G ++ +FR S+ + R + + + SH Sbjct: 218 GQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGS-SFLYDNCTACTCRDSTVVCK--RKCSH 274 Query: 153 RGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN 212 G Q+ G + ++ + +VC K + GE W + C +C C Sbjct: 275 PGGCDQGQE--GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSS-------INCTICACV 325 Query: 213 VTKQECKKIHCPNRYPCKYPQKIDGK-CCKVCPGK 246 + EC+ C C + ++ K CC +C K Sbjct: 326 KGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360 Score = 47.0 bits (110), Expect = 3e-05 Identities = 47/209 (22%), Positives = 76/209 (36%), Gaps = 29/209 (13%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C ++ Y +W EP L C + +E+G VRC VHC +P+ +CC Sbjct: 108 CTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESG------VRCV-VHCKNPLEHLGMCC 160 Query: 97 PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSH--RG 154 P CPG ++ +G+ F+ ++ + S R+ + P SH G Sbjct: 161 PTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGR--TQCVREVCPILSCPQHLSHIPPG 218 Query: 155 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVT 214 + + + C+ Y +G S F C CTC + Sbjct: 219 QCCPKCLGQRKVFDLPFGS-------CLFRSDVYDNGSS-------FLYDNCTACTCRDS 264 Query: 215 KQECKKIHCPNRYPCKYPQKIDGKCCKVC 243 CK+ C + C Q+ CC+ C Sbjct: 265 TVVCKR-KCSHPGGCDQGQE---GCCEEC 289 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/205 (22%), Positives = 73/205 (35%), Gaps = 51/205 (24%) Query: 62 CVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPA 119 C+ C+C N V C R +CP + C + CC +C G ++ ++ PA Sbjct: 67 CIMCVCL-NKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125 Query: 120 NREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQ 179 +P RQ G + +S G + N +H Sbjct: 126 -------------EPCVLRQC-----------QEGVVTES----GVRCVVHCKNPLEHLG 157 Query: 180 VC-------VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 232 +C V G Y GE + P +C C+C + +C + CP P Sbjct: 158 MCCPTCPGCVFEGVQYQEGEEFQPEGS-----KCTKCSCTGGRTQCVREVCP---ILSCP 209 Query: 233 QKID----GKCCKVCPG-KKAKELP 252 Q + G+CC C G +K +LP Sbjct: 210 QHLSHIPPGQCCPKCLGQRKVFDLP 234 Score = 32.3 bits (72), Expect = 0.72 Identities = 23/86 (26%), Positives = 30/86 (34%), Gaps = 10/86 (11%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 C G TY+ W CVL C + C CK P + G CC Sbjct: 108 CTYEGNTYNSSFKWQSPAEP-----CVLRQCQEGVVTESGVRCVVH--CKNPLEHLGMCC 160 Query: 241 KVCPG---KKAKELPGQSFDNKGYFC 263 CPG + + G+ F +G C Sbjct: 161 PTCPGCVFEGVQYQEGEEFQPEGSKC 186 >gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] Length = 955 Score = 55.5 bits (132), Expect = 8e-08 Identities = 61/247 (24%), Positives = 89/247 (36%), Gaps = 52/247 (21%) Query: 2 RKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDK--KYRVGERWHPYLEPYGL 59 R++W++G + F T Q T C D ++ +G+ W P +P Sbjct: 545 REEWRLGPGQCCF------------TCQEPTPSTGCSLDDNGVEFPIGQIWSPG-DP--- 588 Query: 60 VYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPA 119 C CIC +G+V C R C + C P+ IP CCP C + G IF Sbjct: 589 --CELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDCSAGCTYT-----GRIF---- 636 Query: 120 NREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNK-HKHG 178 Y+ + PS LS L+ S S I H G Sbjct: 637 -------YNNETF---PSVLDPCLSCI--------CLLGSVACSPVDCPITCTYPFHPDG 678 Query: 179 QVC-VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDG 237 + C V Y + + + C CTC + + C+K+ C + C P + G Sbjct: 679 ECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPC--QRACADPALLPG 736 Query: 238 KCCKVCP 244 CC CP Sbjct: 737 DCCSSCP 743 Score = 42.0 bits (97), Expect = 0.001 Identities = 52/203 (25%), Positives = 72/203 (35%), Gaps = 36/203 (17%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL---CCPRCPGDGELSWEHSDGDIFRQP 118 C C C E+G V C +VRC C P IP CCP C G ++GD+F P Sbjct: 404 CSQCWC-EDGKVTCEKVRC-EAACSHP--IPSRDGGCCPSCTGCFHSGVVRAEGDVF-SP 458 Query: 119 ANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHG 178 N AG +S Q T V + Sbjct: 459 PNENCTVCV----------CLAGNVSCISPECPSGPCQTPPQTDCCTCVPV--------- 499 Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPN-RYPCKYPQKIDG 237 C +G+ Y+ G + + G EC C C + EC + CP P + + G Sbjct: 500 -RCYFHGRWYADGAVF-----SGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPG 553 Query: 238 KCCKVCPGKKAKELPGQSFDNKG 260 +CC C ++ G S D+ G Sbjct: 554 QCCFTC--QEPTPSTGCSLDDNG 574 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 44.3 bits (103), Expect = 2e-04 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 12/80 (15%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 C NG+ Y + + W P C +C C+ C KI C + C P G+CC Sbjct: 41 CTQNGQMYLNRDIWKP-------APCQICVCDNGAILCDKIECQDVLDCADPVTPPGECC 93 Query: 241 KVCPGKKAKELPGQSFDNKG 260 VC + PG N G Sbjct: 94 PVC-----SQTPGGGNTNFG 108 Score = 42.7 bits (99), Expect = 5e-04 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 34 ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNV-HCLSPVHIP 92 E C + Y + W P C C+C +NG +LC ++ C +V C PV P Sbjct: 38 EIACTQNGQMYLNRDIWKP-------APCQICVC-DNGAILCDKIECQDVLDCADPVTPP 89 Query: 93 HLCCPRC---PGDGELSW 107 CCP C PG G ++ Sbjct: 90 GECCPVCSQTPGGGNTNF 107 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 43.9 bits (102), Expect = 2e-04 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 7/64 (10%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 CV NG Y + W P C +C C+ K C + C C + +G+CC Sbjct: 40 CVQNGLRYHDRDVWKPE-------PCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECC 92 Query: 241 KVCP 244 VCP Sbjct: 93 PVCP 96 Score = 37.4 bits (85), Expect = 0.022 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 9/69 (13%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH-LC 95 C+ +Y + W P EP C C+C +NG VLC V C +P C Sbjct: 40 CVQNGLRYHDRDVWKP--EP-----CRICVC-DNGKVLCDDVICDETKNCPGAEVPEGEC 91 Query: 96 CPRCPGDGE 104 CP CP E Sbjct: 92 CPVCPDGSE 100 >gi|122937446 von Willebrand factor C domain-containing protein 2-like [Homo sapiens] Length = 222 Score = 43.9 bits (102), Expect = 2e-04 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 7/75 (9%) Query: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84 G + K + +C + K Y++ E + P P C C C + V C C Sbjct: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156 Query: 85 CLSPVHIPHLCCPRC 99 C++PV+ P CCP C Sbjct: 157 CVNPVYEPEQCCPVC 171 >gi|40317626 thrombospondin 1 precursor [Homo sapiens] Length = 1170 Score = 43.5 bits (101), Expect = 3e-04 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 173 NKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 232 N+ + +C NG Y + E W + C C C + CKK+ CP PC Sbjct: 310 NELRRPPLCYHNGVQYRNNEEWT-------VDSCTECHCQNSVTICKKVSCP-IMPCSNA 361 Query: 233 QKIDGKCCKVC 243 DG+CC C Sbjct: 362 TVPDGECCPRC 372 Score = 37.7 bits (86), Expect = 0.017 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 9/67 (13%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96 C +YR E W + C C C +N +C +V CP + C + CC Sbjct: 318 CYHNGVQYRNNEEWT-------VDSCTECHC-QNSVTICKKVSCPIMPCSNATVPDGECC 369 Query: 97 PRC-PGD 102 PRC P D Sbjct: 370 PRCWPSD 376 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 43.5 bits (101), Expect = 3e-04 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 7/64 (10%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 CV +G+ Y+ + W P C +C C+ C I C + C P+ G+CC Sbjct: 34 CVQDGQRYNDKDVWKPE-------PCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECC 86 Query: 241 KVCP 244 +CP Sbjct: 87 PICP 90 Score = 40.8 bits (94), Expect = 0.002 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPVHIPHLC 95 C+ ++Y + W P EP C C+C + G VLC + C +V CLSP C Sbjct: 34 CVQDGQRYNDKDVWKP--EP-----CRICVC-DTGTVLCDDIICEDVKDCLSPEIPFGEC 85 Query: 96 CPRCPGD 102 CP CP D Sbjct: 86 CPICPTD 92 >gi|40317628 thrombospondin 2 precursor [Homo sapiens] Length = 1172 Score = 43.5 bits (101), Expect = 3e-04 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 8/70 (11%) Query: 174 KHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQ 233 K ++ C +G+ ++ E+W + C CTC K C +I CP C P Sbjct: 313 KTRNMSACWQDGRFFAENETWV-------VDSCTTCTCKKFKTICHQITCPPA-TCASPS 364 Query: 234 KIDGKCCKVC 243 ++G+CC C Sbjct: 365 FVEGECCPSC 374 Score = 39.7 bits (91), Expect = 0.004 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 3/48 (6%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC--PGDGELSW 107 C C C + +C ++ CP C SP + CCP C DGE W Sbjct: 338 CTTCTCKKF-KTICHQITCPPATCASPSFVEGECCPSCLHSVDGEEGW 384 >gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] Length = 839 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236 + C G TY ESW I C CTC +C+ + CPN P K +D Sbjct: 295 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 346 Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273 GKCCK C K + G++ + + G Y C ++TM + ES Sbjct: 347 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 394 Score = 35.8 bits (81), Expect = 0.065 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ + Y G+ W + C C C + G V C + CP+V C + + Sbjct: 723 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 773 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 774 CCPRCVTD 781 Score = 35.0 bits (79), Expect = 0.11 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88 + E C + YR E W + C NC C NG + C + CPN C + Sbjct: 292 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 342 Query: 89 VHIPHLCCPRC 99 ++ CC C Sbjct: 343 AYVDGKCCKEC 353 Score = 32.7 bits (73), Expect = 0.55 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88 K ++ C FQ + Y GER Y CV C + L CP + C Sbjct: 351 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 407 Query: 89 VHIPHLCCPRCPGDGELSWEHS 110 + + H CC C G S H+ Sbjct: 408 ITLSHSCCKVCKGYDFCSERHN 429 Score = 31.2 bits (69), Expect = 1.6 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%) Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233 +C G+TY GE + + G+ CVL C V C + CP + Sbjct: 356 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 409 Query: 234 KIDGKCCKVCPG 245 + CCKVC G Sbjct: 410 -LSHSCCKVCKG 420 >gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] Length = 815 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236 + C G TY ESW I C CTC +C+ + CPN P K +D Sbjct: 271 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 322 Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273 GKCCK C K + G++ + + G Y C ++TM + ES Sbjct: 323 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 370 Score = 35.8 bits (81), Expect = 0.065 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ + Y G+ W + C C C + G V C + CP+V C + + Sbjct: 699 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 749 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 750 CCPRCVTD 757 Score = 35.0 bits (79), Expect = 0.11 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88 + E C + YR E W + C NC C NG + C + CPN C + Sbjct: 268 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 318 Query: 89 VHIPHLCCPRC 99 ++ CC C Sbjct: 319 AYVDGKCCKEC 329 Score = 32.7 bits (73), Expect = 0.55 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88 K ++ C FQ + Y GER Y CV C + L CP + C Sbjct: 327 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 383 Query: 89 VHIPHLCCPRCPGDGELSWEHS 110 + + H CC C G S H+ Sbjct: 384 ITLSHSCCKVCKGYDFCSERHN 405 Score = 31.2 bits (69), Expect = 1.6 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%) Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233 +C G+TY GE + + G+ CVL C V C + CP + Sbjct: 332 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 385 Query: 234 KIDGKCCKVCPG 245 + CCKVC G Sbjct: 386 -LSHSCCKVCKG 396 >gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236 + C G TY ESW I C CTC +C+ + CPN P K +D Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323 Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273 GKCCK C K + G++ + + G Y C ++TM + ES Sbjct: 324 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371 Score = 35.8 bits (81), Expect = 0.065 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ + Y G+ W + C C C + G V C + CP+V C + + Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 751 CCPRCVTD 758 Score = 35.0 bits (79), Expect = 0.11 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88 + E C + YR E W + C NC C NG + C + CPN C + Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319 Query: 89 VHIPHLCCPRC 99 ++ CC C Sbjct: 320 AYVDGKCCKEC 330 Score = 32.7 bits (73), Expect = 0.55 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88 K ++ C FQ + Y GER Y CV C + L CP + C Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384 Query: 89 VHIPHLCCPRCPGDGELSWEHS 110 + + H CC C G S H+ Sbjct: 385 ITLSHSCCKVCKGYDFCSERHN 406 Score = 31.2 bits (69), Expect = 1.6 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%) Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233 +C G+TY GE + + G+ CVL C V C + CP + Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386 Query: 234 KIDGKCCKVCPG 245 + CCKVC G Sbjct: 387 -LSHSCCKVCKG 397 >gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] Length = 866 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236 + C G TY ESW I C CTC +C+ + CPN P K +D Sbjct: 322 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 373 Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273 GKCCK C K + G++ + + G Y C ++TM + ES Sbjct: 374 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 421 Score = 35.8 bits (81), Expect = 0.065 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ + Y G+ W + C C C + G V C + CP+V C + + Sbjct: 750 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 800 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 801 CCPRCVTD 808 Score = 35.0 bits (79), Expect = 0.11 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88 + E C + YR E W + C NC C NG + C + CPN C + Sbjct: 319 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 369 Query: 89 VHIPHLCCPRC 99 ++ CC C Sbjct: 370 AYVDGKCCKEC 380 Score = 32.7 bits (73), Expect = 0.55 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88 K ++ C FQ + Y GER Y CV C + L CP + C Sbjct: 378 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 434 Query: 89 VHIPHLCCPRCPGDGELSWEHS 110 + + H CC C G S H+ Sbjct: 435 ITLSHSCCKVCKGYDFCSERHN 456 Score = 31.2 bits (69), Expect = 1.6 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%) Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233 +C G+TY GE + + G+ CVL C V C + CP + Sbjct: 383 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 436 Query: 234 KIDGKCCKVCPG 245 + CCKVC G Sbjct: 437 -LSHSCCKVCKG 447 >gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236 + C G TY ESW I C CTC +C+ + CPN P K +D Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323 Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273 GKCCK C K + G++ + + G Y C ++TM + ES Sbjct: 324 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371 Score = 35.8 bits (81), Expect = 0.065 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ + Y G+ W + C C C + G V C + CP+V C + + Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 751 CCPRCVTD 758 Score = 35.0 bits (79), Expect = 0.11 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88 + E C + YR E W + C NC C NG + C + CPN C + Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319 Query: 89 VHIPHLCCPRC 99 ++ CC C Sbjct: 320 AYVDGKCCKEC 330 Score = 32.7 bits (73), Expect = 0.55 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88 K ++ C FQ + Y GER Y CV C + L CP + C Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384 Query: 89 VHIPHLCCPRCPGDGELSWEHS 110 + + H CC C G S H+ Sbjct: 385 ITLSHSCCKVCKGYDFCSERHN 406 Score = 31.2 bits (69), Expect = 1.6 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%) Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233 +C G+TY GE + + G+ CVL C V C + CP + Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386 Query: 234 KIDGKCCKVCPG 245 + CCKVC G Sbjct: 387 -LSHSCCKVCKG 397 >gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] Length = 763 Score = 43.1 bits (100), Expect = 4e-04 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 236 + C +G Y +SW C CTC EC+++ CP N P P I Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324 Query: 237 GKCCKVCPGK 246 G+CCKVC K Sbjct: 325 GQCCKVCRPK 334 Score = 40.4 bits (93), Expect = 0.003 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 10/71 (14%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88 H E C YR + W +C NC C ++G V C R+ CP ++C P Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320 Query: 89 VHIPHLCCPRC 99 VHI CC C Sbjct: 321 VHIAGQCCKVC 331 Score = 40.0 bits (92), Expect = 0.003 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%) Query: 37 CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ K YR G+ W C C C E G V C + CPN+ C + Sbjct: 647 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 697 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 698 CCPRCVSD 705 Score = 36.2 bits (82), Expect = 0.050 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%) Query: 186 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243 K Y G++W + C C C + +C + CPN C+Y ++G+CC C Sbjct: 654 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 702 >gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] Length = 810 Score = 43.1 bits (100), Expect = 4e-04 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 236 + C +G Y +SW C CTC EC+++ CP N P P I Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324 Query: 237 GKCCKVCPGK 246 G+CCKVC K Sbjct: 325 GQCCKVCRPK 334 Score = 40.4 bits (93), Expect = 0.003 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 10/71 (14%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88 H E C YR + W +C NC C ++G V C R+ CP ++C P Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320 Query: 89 VHIPHLCCPRC 99 VHI CC C Sbjct: 321 VHIAGQCCKVC 331 Score = 40.0 bits (92), Expect = 0.003 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%) Query: 37 CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94 C+ Q+ K YR G+ W C C C E G V C + CPN+ C + Sbjct: 694 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 744 Query: 95 CCPRCPGD 102 CCPRC D Sbjct: 745 CCPRCVSD 752 Score = 36.2 bits (82), Expect = 0.050 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%) Query: 186 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243 K Y G++W + C C C + +C + CPN C+Y ++G+CC C Sbjct: 701 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 749 >gi|108773804 Fraser syndrome 1 [Homo sapiens] Length = 4011 Score = 43.1 bits (100), Expect = 4e-04 Identities = 62/269 (23%), Positives = 87/269 (32%), Gaps = 64/269 (23%) Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP---VHIPH 93 C ++ ++ GE W L C C+C NG C +C + C V +P Sbjct: 159 CSYEGHVFQDGEDWR-------LSRCAKCLC-RNGVAQCFTAQCQPLFCNQDETVVRVPG 210 Query: 94 LCCPR-----CPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDP-PPSRQAGGLSRFP 147 CCP+ C G++ +EH + R H P R G SR Sbjct: 211 KCCPQCSARSCSAAGQV-YEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSR-- 267 Query: 148 GARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECV 207 AR H + +G+ C +G E W + F + + Sbjct: 268 -ARRHGQCCEECVSPAGS---------------CSYDGVVRYQDEMWKGSACEFCMCDHG 311 Query: 208 LCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEET 267 TC EC K+ C + +DGKCC C GY EET Sbjct: 312 QVTCQT--GECAKVECARDEELIH---LDGKCCPEC------------ISRNGYCVYEET 354 Query: 268 MPVYESVFMEDGETTRKIALETERPPQVE 296 GE A E +R P+ E Sbjct: 355 -----------GEFMSSNASEVKRIPEGE 372 Score = 36.6 bits (83), Expect = 0.038 Identities = 51/244 (20%), Positives = 74/244 (30%), Gaps = 53/244 (21%) Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH- 90 HSE C++QD W P C +C C V+C C N C Sbjct: 23 HSEGACVYQDSLLADATIWKP-------DSCQSCRC-HGDIVICKPAVCRNPQCAFEKGE 74 Query: 91 ----IPHLCCPRC----PGD---GELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQ 139 + CCP C PG + EH + H R P P Sbjct: 75 VLQIAANQCCPECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLS 134 Query: 140 AG--GLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPN 197 G L+ P G+ + + G+ C G + GE W Sbjct: 135 CGHQELAFIP---------------EGSCCPVCVG----LGKPCSYEGHVFQDGEDWR-- 173 Query: 198 LRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQ---KIDGKCCKVCPGKKAKELPGQ 254 + C C C +C C + C + ++ GKCC C + GQ Sbjct: 174 -----LSRCAKCLCRNGVAQCFTAQCQPLF-CNQDETVVRVPGKCCPQCSARSC-SAAGQ 226 Query: 255 SFDN 258 +++ Sbjct: 227 VYEH 230 >gi|109150416 peroxidasin [Homo sapiens] Length = 1479 Score = 39.7 bits (91), Expect = 0.004 Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 7/72 (9%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240 CV G GES H N + C +C C + C CP C P I G CC Sbjct: 1415 CVDAG-----GES-HANNTKWKKDACTICECKDGQVTCFVEACPPA-TCAVPVNIPGACC 1467 Query: 241 KVCPGKKAKELP 252 VC K+A+E P Sbjct: 1468 PVCLQKRAEEKP 1479 Score = 39.3 bits (90), Expect = 0.006 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99 C C C + G V C CP C PV+IP CCP C Sbjct: 1434 CTICECKD-GQVTCFVEACPPATCAVPVNIPGACCPVC 1470 >gi|126517478 peroxidasin homolog-like [Homo sapiens] Length = 1463 Score = 38.9 bits (89), Expect = 0.008 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDG 103 C +CIC E+G V C CP C SP + CCP C G Sbjct: 1414 CTHCIC-ESGQVTCVVEICPPAPCPSPELVKGTCCPVCRDRG 1454 Score = 33.9 bits (76), Expect = 0.25 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 205 ECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243 +C C C + C CP PC P+ + G CC VC Sbjct: 1413 DCTHCICESGQVTCVVEICPPA-PCPSPELVKGTCCPVC 1450 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 38.1 bits (87), Expect = 0.013 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 8/65 (12%) Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQKIDGKC 239 C G++Y+ + W P C +C C+ C I C ++ C P+ G+C Sbjct: 32 CSHLGQSYADRDVWKPE-------PCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGEC 84 Query: 240 CKVCP 244 C VCP Sbjct: 85 CAVCP 89 >gi|188497705 BRCA1 associated protein [Homo sapiens] Length = 592 Score = 35.0 bits (79), Expect = 0.11 Identities = 27/141 (19%), Positives = 62/141 (43%), Gaps = 11/141 (7%) Query: 238 KCCKVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEV 297 +C P +K+LP D +F G ++ + + M +T + +L+ + + Sbjct: 109 ECINAAPDSPSKQLP----DQISFFSGNPSVEIVHGI-MHLYKTNKMTSLKEDVRRSAML 163 Query: 298 HVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQIS-----QMCS 352 + T+ + H + K E + K++ +T +Q+ + + AQ C+ Sbjct: 164 CILTVPAAMTSH-DLMKFVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCN 222 Query: 353 SRVCRTELEDLVKVLYLERSE 373 R + +D+ +++Y+ER+E Sbjct: 223 GRQFNSIEDDVCQLVYVERAE 243 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.456 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,696,574 Number of Sequences: 37866 Number of extensions: 900628 Number of successful extensions: 2462 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 2198 Number of HSP's gapped (non-prelim): 211 length of query: 377 length of database: 18,247,518 effective HSP length: 104 effective length of query: 273 effective length of database: 14,309,454 effective search space: 3906480942 effective search space used: 3906480942 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.