Guide to the Human Genome
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Search of human proteins with 221316568

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]        817   0.0  
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]         631   0.0  
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]        626   e-180
gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]        626   e-180
gi|40353769 chordin-like 2 [Homo sapiens]                             157   1e-38
gi|30089980 chordin [Homo sapiens]                                     78   1e-14
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]    70   4e-12
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]    69   9e-12
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa...    60   4e-09
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]                59   5e-09
gi|37693519 BMP-binding endothelial regulator precursor protein ...    59   9e-09
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]    55   8e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       44   2e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      44   2e-04
gi|122937446 von Willebrand factor C domain-containing protein 2...    44   2e-04
gi|40317626 thrombospondin 1 precursor [Homo sapiens]                  44   3e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    44   3e-04
gi|40317628 thrombospondin 2 precursor [Homo sapiens]                  44   3e-04
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]               44   3e-04
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]               44   3e-04
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]     44   3e-04
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]               44   3e-04
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]       44   3e-04
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]             43   4e-04
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]             43   4e-04
gi|108773804 Fraser syndrome 1 [Homo sapiens]                          43   4e-04
gi|109150416 peroxidasin [Homo sapiens]                                40   0.004
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   39   0.008
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      38   0.013
gi|188497705 BRCA1 associated protein [Homo sapiens]                   35   0.11 

>gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]
          Length = 377

 Score =  817 bits (2111), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
           MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60

Query: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120
           YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN
Sbjct: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120

Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180
           REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV
Sbjct: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC
Sbjct: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240

Query: 241 KVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300
           KVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW
Sbjct: 241 KVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300

Query: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360
           TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL
Sbjct: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360

Query: 361 EDLVKVLYLERSEKGHC 377
           EDLVKVLYLERSEKGHC
Sbjct: 361 EDLVKVLYLERSEKGHC 377


>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
          Length = 456

 Score =  631 bits (1627), Expect = 0.0
 Identities = 295/316 (93%), Positives = 297/316 (93%), Gaps = 1/316 (0%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121
           C  C CSE GNV C    CP + C  PV +P  CC  C GDGELSWEHSDGDIFRQPANR
Sbjct: 142 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 200

Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181
           EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC
Sbjct: 201 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 260

Query: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241
           VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK
Sbjct: 261 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 320

Query: 242 VCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWT 301
           VCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWT
Sbjct: 321 VCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWT 380

Query: 302 IRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELE 361
           IRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELE
Sbjct: 381 IRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTELE 440

Query: 362 DLVKVLYLERSEKGHC 377
           DLVKVLYLERSEKGHC
Sbjct: 441 DLVKVLYLERSEKGHC 456



 Score =  236 bits (602), Expect = 3e-62
 Identities = 125/245 (51%), Positives = 140/245 (57%), Gaps = 65/245 (26%)

Query: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
           MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60

Query: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120
           YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP                 P N
Sbjct: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDS-------------LPPVN 107

Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180
            +                                    S + +GT  Q        HG++
Sbjct: 108 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 127

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
            V+ G      ++  PN       +C  C+C+     C    CP +  C +P  +   CC
Sbjct: 128 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 175

Query: 241 KVCPG 245
           +VC G
Sbjct: 176 RVCRG 180



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89
           KH +  C+   K Y  GE WHP L  +G+V CV C C+      C ++ CPN + C  P 
Sbjct: 255 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 312

Query: 90  HIPHLCCPRCPG 101
            I   CC  CPG
Sbjct: 313 KIDGKCCKVCPG 324


>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
          Length = 457

 Score =  626 bits (1615), Expect = e-180
 Identities = 295/317 (93%), Positives = 297/317 (93%), Gaps = 2/317 (0%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121
           C  C CSE GNV C    CP + C  PV +P  CC  C GDGELSWEHSDGDIFRQPANR
Sbjct: 142 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 200

Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181
           EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC
Sbjct: 201 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 260

Query: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241
           VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK
Sbjct: 261 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 320

Query: 242 VCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300
           VCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW
Sbjct: 321 VCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 380

Query: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360
           TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL
Sbjct: 381 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 440

Query: 361 EDLVKVLYLERSEKGHC 377
           EDLVKVLYLERSEKGHC
Sbjct: 441 EDLVKVLYLERSEKGHC 457



 Score =  236 bits (602), Expect = 3e-62
 Identities = 125/245 (51%), Positives = 140/245 (57%), Gaps = 65/245 (26%)

Query: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
           MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60

Query: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120
           YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP                 P N
Sbjct: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDS-------------LPPVN 107

Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180
            +                                    S + +GT  Q        HG++
Sbjct: 108 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 127

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
            V+ G      ++  PN       +C  C+C+     C    CP +  C +P  +   CC
Sbjct: 128 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 175

Query: 241 KVCPG 245
           +VC G
Sbjct: 176 RVCRG 180



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89
           KH +  C+   K Y  GE WHP L  +G+V CV C C+      C ++ CPN + C  P 
Sbjct: 255 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 312

Query: 90  HIPHLCCPRCPG 101
            I   CC  CPG
Sbjct: 313 KIDGKCCKVCPG 324


>gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
          Length = 458

 Score =  626 bits (1615), Expect = e-180
 Identities = 295/317 (93%), Positives = 297/317 (93%), Gaps = 2/317 (0%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121
           C  C CSE GNV C    CP + C  PV +P  CC  C GDGELSWEHSDGDIFRQPANR
Sbjct: 143 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 201

Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181
           EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC
Sbjct: 202 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 261

Query: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241
           VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK
Sbjct: 262 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 321

Query: 242 VCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300
           VCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW
Sbjct: 322 VCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 381

Query: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360
           TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL
Sbjct: 382 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 441

Query: 361 EDLVKVLYLERSEKGHC 377
           EDLVKVLYLERSEKGHC
Sbjct: 442 EDLVKVLYLERSEKGHC 458



 Score =  238 bits (608), Expect = 5e-63
 Identities = 126/245 (51%), Positives = 141/245 (57%), Gaps = 64/245 (26%)

Query: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
           MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1   MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60

Query: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120
           YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP D               P N
Sbjct: 61  YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDS------------LPPVN 108

Query: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180
            +                                    S + +GT  Q        HG++
Sbjct: 109 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 128

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
            V+ G      ++  PN       +C  C+C+     C    CP +  C +P  +   CC
Sbjct: 129 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 176

Query: 241 KVCPG 245
           +VC G
Sbjct: 177 RVCRG 181



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89
           KH +  C+   K Y  GE WHP L  +G+V CV C C+      C ++ CPN + C  P 
Sbjct: 256 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 313

Query: 90  HIPHLCCPRCPG 101
            I   CC  CPG
Sbjct: 314 KIDGKCCKVCPG 325


>gi|40353769 chordin-like 2 [Homo sapiens]
          Length = 451

 Score =  157 bits (397), Expect = 1e-38
 Identities = 86/252 (34%), Positives = 122/252 (48%), Gaps = 25/252 (9%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121
           CV C C+E G + C    CP   C +P+ +P  CC  C  +     E SD +        
Sbjct: 138 CVLCSCTE-GQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEAS---EQSDEE-------- 185

Query: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMD---------SQQASGTIVQIVIN 172
           ++  S H   +   P     G  R PG  +  G              + A  T V+IV+ 
Sbjct: 186 DSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLK 245

Query: 173 NKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 232
            KHK  + CV  GKTYSHGE WHP  RAFG + C+LCTC   +Q+C+++ CP  YPC++P
Sbjct: 246 EKHK--KACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHP 303

Query: 233 QKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERP 292
           +K+ GKCCK+CP  KA   PG S  +           +  +      +  R+ ALE E  
Sbjct: 304 EKVAGKCCKICPEDKAD--PGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEAS 361

Query: 293 PQVEVHVWTIRK 304
             VE+++W + K
Sbjct: 362 DLVEIYLWKLVK 373



 Score = 99.4 bits (246), Expect = 5e-21
 Identities = 60/217 (27%), Positives = 86/217 (39%), Gaps = 65/217 (29%)

Query: 34  ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH 93
           + +C+F  K+Y  GE WHPYLEP GL+YC+ C CSE  +V C R+ CP VHC  PV  P 
Sbjct: 30  DMFCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQ 89

Query: 94  LCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 153
            CCP+C                                 +P       GL   P +  H 
Sbjct: 90  QCCPKC--------------------------------VEP---HTPSGLRAPPKSCQHN 114

Query: 154 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 213
           G +                  ++HG++       +    S  PN       +CVLC+C  
Sbjct: 115 GTM------------------YQHGEIF----SAHELFPSRLPN-------QCVLCSCTE 145

Query: 214 TKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE 250
            +  C    CP    C  P  +   CC+ C  + +++
Sbjct: 146 GQIYCGLTTCPEP-GCPAPLPLPDSCCQACKDEASEQ 181



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 28/73 (38%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89
           KH +  C+   K Y  GE WHP    +G + C+ C C E+G   C RV CP  + C  P 
Sbjct: 247 KHKKA-CVHGGKTYSHGEVWHPAFRAFGPLPCILCTC-EDGRQDCQRVTCPTEYPCRHPE 304

Query: 90  HIPHLCCPRCPGD 102
            +   CC  CP D
Sbjct: 305 KVAGKCCKICPED 317


>gi|30089980 chordin [Homo sapiens]
          Length = 955

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 57/211 (27%), Positives = 75/211 (35%), Gaps = 67/211 (31%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C F+ ++   G RW P  +P     C  C C     V+C  V CP   C  PV  P  CC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156
           P CP   ++                       R     P SR  G    F G RS R A 
Sbjct: 760 PVCPEKQDV-----------------------RDLPGLPRSRDPGEGCYFDGDRSWRAA- 795

Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--NVT 214
                                             G  WHP +  FG+++C +CTC     
Sbjct: 796 ----------------------------------GTRWHPVVPPFGLIKCAVCTCKGGTG 821

Query: 215 KQECKKIHCPNRYPCKYPQKID-GKCCKVCP 244
           +  C+K+ CP R  C  P +++   CCK CP
Sbjct: 822 EVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 14/118 (11%)

Query: 37  CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84
           C F  K Y + E WHP L EP+G++ CV C C            G V C  ++  CP   
Sbjct: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110

Query: 85  CLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 142
           C  P  +P  CC  CP +   S     G  F  P  R+  H  +    +P    +A G
Sbjct: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 17/93 (18%)

Query: 181 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 227
           C   GK Y+  E+WHP+L   FG++ CVLC C             +  CK I   CP   
Sbjct: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109

Query: 228 PCKYPQKIDGKCCKVCPGKKA---KELPGQSFD 257
            C  P+++ G CC+ CP +++   ++  G SF+
Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFE 142



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 6/74 (8%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           C   G+   HG  W PN        C LCTC      C  + CP    C +P +   +CC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759

Query: 241 KVCPGKK-AKELPG 253
            VCP K+  ++LPG
Sbjct: 760 PVCPEKQDVRDLPG 773



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 4/64 (6%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95
           C F  + +   + WHP + P+G + C+ C C   G   C R  C   + C S       C
Sbjct: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928

Query: 96  CPRC 99
           C RC
Sbjct: 929 CSRC 932


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 63/221 (28%), Positives = 79/221 (35%), Gaps = 41/221 (18%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C +  + Y  G+ +     P     C  C C ++G V CS V CP   C  P   P  CC
Sbjct: 425 CTYHSQVYANGQNFTDADSP-----CHACHC-QDGTVTCSLVDCPPTTCARPQSGPGQCC 478

Query: 97  PRCPGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 153
           PRCP D  L  E   DG+ F  P +  +E R     +H  P P  +A      PG     
Sbjct: 479 PRCP-DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGT---- 533

Query: 154 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW-HPNLRAFGIVECVLCTCN 212
                    SG                C   GK Y  G  + HP+        C LC C 
Sbjct: 534 ---CCPNDCSG----------------CAFGGKEYPSGADFPHPS------DPCRLCRCL 568

Query: 213 VTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPG 253
               +C    C    PC  P  + G+CC  CP       PG
Sbjct: 569 SGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAPAGCPRPG 608



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 55/208 (26%), Positives = 83/208 (39%), Gaps = 38/208 (18%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
           C    +++R GE       P G    C +C C+ NG+V C  + CP V C  P  IP  C
Sbjct: 252 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 303

Query: 96  CPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGA 155
           CP C G      ++   + FR     + R    R       S QAG +S           
Sbjct: 304 CPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS----------- 342

Query: 156 LMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTK 215
             + Q+   T   +  + + +    C  +G+ ++ G  W P+ R      C  C C    
Sbjct: 343 -CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PCTACVCQDGV 395

Query: 216 QECKKIHCPNRYPCKYPQKIDGKCCKVC 243
            +C  + CP   PC++P +  G CC  C
Sbjct: 396 PKCGAVLCPPA-PCQHPTQPPGACCPSC 422



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 55/212 (25%), Positives = 76/212 (35%), Gaps = 43/212 (20%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C    + Y  GE + P         C  C C   G V C    C  ++CL     P  CC
Sbjct: 138 CSQNGQTYGNGETFSPDA-------CTTCRCL-TGAVQCQGPSCSELNCLESCTPPGECC 189

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156
           P C  +G   WEH  G  +  P +   R       +     R+   L  +P         
Sbjct: 190 PICCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQCRQRECASLCPYP--------- 237

Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE---SWHPNLRAFGIVECVLCTCNV 213
             ++   GT   +           C  NG+ +  GE   S  P         C  C C  
Sbjct: 238 --ARPLPGTCCPVCDG--------CFLNGREHRSGEPVGSGDP---------CSHCRCAN 278

Query: 214 TKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245
              +C+ + CP   PC++P KI G+CC VC G
Sbjct: 279 GSVQCEPLPCPP-VPCRHPGKIPGQCCPVCDG 309



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 56/222 (25%), Positives = 79/222 (35%), Gaps = 58/222 (26%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C F  K+Y  G  +    +P  L  C++      GNV C   RC  + C  PV +P  CC
Sbjct: 542 CAFGGKEYPSGADFPHPSDPCRLCRCLS------GNVQCLARRCVPLPCPEPVLLPGECC 595

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP--PSRQA----GGLS------ 144
           P+CP                +P    A H+ H+ ++ PP  P R+     G +S      
Sbjct: 596 PQCPAPAGCP----------RPG---AAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642

Query: 145 -RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGI 203
              P A   +G    S                     C+  GK ++ GE +     A   
Sbjct: 643 PPAPCAHPRQGPCCPSCDG------------------CLYQGKEFASGERFPSPTAA--- 681

Query: 204 VECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245
             C LC C      C+   C     C +P +  G CC  C G
Sbjct: 682 --CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCDG 718



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 62/232 (26%), Positives = 88/232 (37%), Gaps = 38/232 (16%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C +Q  +Y+  E +   L+  GL  CV C C + G V C    CP   C  P     LC 
Sbjct: 310 CEYQGHQYQSQETFR--LQERGL--CVRCSC-QAGEVSCEEQECPVTPCALPASGRQLC- 363

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156
           P C  DGE   E ++G +  +P  R       +   D  P  + G +   P    H    
Sbjct: 364 PACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP--KCGAVLCPPAPCQH---- 410

Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQ 216
               Q  G       +  + H QV  +NG+ ++  +S            C  C C     
Sbjct: 411 --PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-----------PCHACHCQDGTV 455

Query: 217 ECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE---LPGQSFDNKGYFCGE 265
            C  + CP    C  PQ   G+CC  CP    +E   + G+SF +    C E
Sbjct: 456 TCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 506



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 52/218 (23%), Positives = 77/218 (35%), Gaps = 46/218 (21%)

Query: 37   CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
            C+ Q ++++ GE +     P G   C  C C + G V C R++CP + C   V     CC
Sbjct: 837  CLSQGREHQDGEEFEG---PAGS--CEWCRC-QAGQVSCVRLQCPPLPCKLQVTERGSCC 890

Query: 97   PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156
            PRC G      EH +G                 S + PP S  +  +        H G +
Sbjct: 891  PRCRGCLAHGEEHPEG-----------------SRWVPPDSACSSCV-------CHEGVV 926

Query: 157  MDSQQASGTIVQIVINNKH---KHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 213
              ++    +         H        C   G+ Y  GES+ P     G   C +C C  
Sbjct: 927  TCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQP-----GADPCEVCICEP 981

Query: 214  TKQ-----ECKKIHCPNRYPCKYPQKI---DGKCCKVC 243
              +      C +  CP+   C   Q +      CC  C
Sbjct: 982  QPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC 1019



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 59/240 (24%), Positives = 76/240 (31%), Gaps = 57/240 (23%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C++Q K++  GER+     P     C  C+C E G+V C    C    C  P      CC
Sbjct: 662 CLYQGKEFASGERF-----PSPTAACHLCLCWE-GSVSCEPKACAPALCPFPARGD--CC 713

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF---------P 147
           P C G   L   +     F  P                 P      L  F         P
Sbjct: 714 PDCDGCEYLGESYLSNQEFPDPRE---------------PCNLCTCLGGFVTCGRRPCEP 758

Query: 148 GARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECV 207
              SH   L+ S     T             Q C  +G T + GE+    L       C 
Sbjct: 759 PGCSH--PLIPSGHCCPTC------------QGCRYHGVTTASGETLPDPLDP----TCS 800

Query: 208 LCTCNVTKQECKKIHCPNRYPCKYPQKIDGKC----CKVCPGKKAKELPGQSFDNKGYFC 263
           LCTC      C+K  CP   P   P    G C    C  C  +  +   G+ F+     C
Sbjct: 801 LCTCQEGSMRCQKKPCP---PALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSC 857



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 49/217 (22%), Positives = 74/217 (34%), Gaps = 37/217 (17%)

Query: 37   CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENG----NVLCSRVRCPNVHCLSPVHI- 91
            C  + +KY  GE + P  +P     C  CIC        ++ C R +CP++    P  + 
Sbjct: 954  CEHEGRKYEPGESFQPGADP-----CEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLL 1008

Query: 92   ---PHLCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPG 148
               P  CCP C    E     S+G +  + A  +  ++            QA      P 
Sbjct: 1009 PPGPQHCCPTC---AEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPL 1065

Query: 149  ARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVL 208
            +  H           G+   +         Q CV  G+  + GE W        +  C  
Sbjct: 1066 SERHT--------PPGSCCPVC----RAPTQSCVHQGREVASGERW-------TVDTCTS 1106

Query: 209  CTCNVTKQECKKIHCP--NRYPCKYPQKIDGKCCKVC 243
            C+C      C+   C   +  P K P    G CC  C
Sbjct: 1107 CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 46/214 (21%), Positives = 67/214 (31%), Gaps = 42/214 (19%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C +  + Y   + +    EP  L  C+       G V C R  C    C  P+     CC
Sbjct: 719 CEYLGESYLSNQEFPDPREPCNLCTCLG------GFVTCGRRPCEPPGCSHPLIPSGHCC 772

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREA-----RHSYHRSHYDPPPSRQAGGLSRFPGARS 151
           P C G        + G+    P +        +    R    P P          P    
Sbjct: 773 PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCP----------PALCP 822

Query: 152 HRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC 211
           H         + G     V ++       C+S G+ +  GE +     +     C  C C
Sbjct: 823 H--------PSPGPCFCPVCHS-------CLSQGREHQDGEEFEGPAGS-----CEWCRC 862

Query: 212 NVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245
              +  C ++ CP   PCK      G CC  C G
Sbjct: 863 QAGQVSCVRLQCP-PLPCKLQVTERGSCCPRCRG 895



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 8/67 (11%)

Query: 177 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 236
           H + C  NG+TY +GE++ P+        C  C C     +C+   C +   C       
Sbjct: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLTGAVQCQGPSC-SELNCLESCTPP 185

Query: 237 GKCCKVC 243
           G+CC +C
Sbjct: 186 GECCPIC 192


>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
          Length = 814

 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 62/216 (28%), Positives = 78/216 (36%), Gaps = 41/216 (18%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C +  + Y  G+ +     P     C  C C ++G V CS V CP   C  P   P  CC
Sbjct: 483 CTYHSQVYANGQNFTDADSP-----CHACHC-QDGTVTCSLVDCPPTTCARPQSGPGQCC 536

Query: 97  PRCPGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 153
           PRCP D  L  E   DG+ F  P +  +E R     +H  P P  +A      PG     
Sbjct: 537 PRCP-DCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGT---- 591

Query: 154 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW-HPNLRAFGIVECVLCTCN 212
                    SG                C   GK Y  G  + HP+        C LC C 
Sbjct: 592 ---CCPNDCSG----------------CAFGGKEYPSGADFPHPS------DPCRLCRCL 626

Query: 213 VTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKA 248
               +C    C    PC  P  + G+CC  CP   A
Sbjct: 627 SGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPA 661



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 57/219 (26%), Positives = 83/219 (37%), Gaps = 43/219 (19%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHI 91
           H +  C ++ + Y  G  +     P     C+ C C  +  V C  ++CP   C  PV  
Sbjct: 187 HCKPGCDYEGQLYEEGVTFLSSSNP-----CLQCTCLRS-RVRCMALKCPPSPCPEPVLR 240

Query: 92  PHLCCPRCPG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGA 149
           P  CCP C G  +G   WEH  G  +  P +   R       +     R+   L  +P  
Sbjct: 241 PGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQCRQRECASLCPYP-- 295

Query: 150 RSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE---SWHPNLRAFGIVEC 206
                    ++   GT   +           C  NG+ +  GE   S  P         C
Sbjct: 296 ---------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVGSGDP---------C 329

Query: 207 VLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 245
             C C     +C+ + CP   PC++P KI G+CC VC G
Sbjct: 330 SHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 55/208 (26%), Positives = 83/208 (39%), Gaps = 38/208 (18%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
           C    +++R GE       P G    C +C C+ NG+V C  + CP V C  P  IP  C
Sbjct: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361

Query: 96  CPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGA 155
           CP C G      ++   + FR     + R    R       S QAG +S           
Sbjct: 362 CPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS----------- 400

Query: 156 LMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTK 215
             + Q+   T   +  + + +    C  +G+ ++ G  W P+ R      C  C C    
Sbjct: 401 -CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PCTACVCQDGV 453

Query: 216 QECKKIHCPNRYPCKYPQKIDGKCCKVC 243
            +C  + CP   PC++P +  G CC  C
Sbjct: 454 PKCGAVLCPPA-PCQHPTQPPGACCPSC 480



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/223 (25%), Positives = 80/223 (35%), Gaps = 55/223 (24%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C F  K+Y  G  +    +P  L  C++      GNV C   RC  + C  PV +P  CC
Sbjct: 600 CAFGGKEYPSGADFPHPSDPCRLCRCLS------GNVQCLARRCVPLPCPEPVLLPGECC 653

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP--PSRQA----GGLS------ 144
           P+CP     +     G          A H+ H+ ++ PP  P R+     G +S      
Sbjct: 654 PQCPAAPAPAGCPRPG----------AAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 703

Query: 145 -RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGI 203
              P A   +G    S                     C+  GK ++ GE +     A   
Sbjct: 704 PPAPCAHPRQGPCCPSCDG------------------CLYQGKEFASGERFPSPTAA--- 742

Query: 204 VECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGK 246
             C LC C      C+   C     C +P +  G CC  C G+
Sbjct: 743 --CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCDGE 780



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 62/232 (26%), Positives = 88/232 (37%), Gaps = 38/232 (16%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C +Q  +Y+  E +   L+  GL  CV C C + G V C    CP   C  P     LC 
Sbjct: 368 CEYQGHQYQSQETFR--LQERGL--CVRCSC-QAGEVSCEEQECPVTPCALPASGRQLC- 421

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156
           P C  DGE   E ++G +  +P  R       +   D  P  + G +   P    H    
Sbjct: 422 PACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP--KCGAVLCPPAPCQH---- 468

Query: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQ 216
               Q  G       +  + H QV  +NG+ ++  +S            C  C C     
Sbjct: 469 --PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-----------PCHACHCQDGTV 513

Query: 217 ECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE---LPGQSFDNKGYFCGE 265
            C  + CP    C  PQ   G+CC  CP    +E   + G+SF +    C E
Sbjct: 514 TCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQE 564



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 45/213 (21%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C    + Y  GE + P         C  C C E G + C++  CP      P   P  CC
Sbjct: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPR----GPCPEPGACC 185

Query: 97  PRC-PGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGA 155
           P C PG       + +G  F   +N   + +  RS                      R  
Sbjct: 186 PHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRS----------------------RVR 223

Query: 156 LMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 213
            M  +       + V+   H     Q C   G  + HG+ W           C +C C  
Sbjct: 224 CMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW-----TTPGDPCRICRCLE 278

Query: 214 TKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 245
              +C++  C +   C YP + + G CC VC G
Sbjct: 279 GHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 14/81 (17%)

Query: 177 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 236
           H + C  NG+TY +GE++ P+        C  C C      C +  CP R PC  P    
Sbjct: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLEGTITCNQKPCP-RGPCPEP---- 181

Query: 237 GKCCKVCPGKKAKELPGQSFD 257
           G CC  C  K   +  GQ ++
Sbjct: 182 GACCPHC--KPGCDYEGQLYE 200



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 8/67 (11%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C++Q K++  GER+     P     C  C+C E G+V C    C    C  P      CC
Sbjct: 723 CLYQGKEFASGERF-----PSPTAACHLCLCWE-GSVSCEPKACAPALCPFPARGD--CC 774

Query: 97  PRCPGDG 103
           P C G+G
Sbjct: 775 PDCDGEG 781


>gi|38348414 von Willebrand factor C domain containing 2 [Homo
           sapiens]
          Length = 325

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 7/71 (9%)

Query: 29  QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
           Q K  + YC F+ K Y+        LE + +  C  C C  NG VLC+   CP   C+ P
Sbjct: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262

Query: 89  VHIPHLCCPRC 99
           V+ P  CCP C
Sbjct: 263 VYEPDQCCPIC 273


>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
          Length = 1036

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 52/201 (25%), Positives = 72/201 (35%), Gaps = 28/201 (13%)

Query: 55  EPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC---PGDGELSWEHS- 110
           E + +  C  C C  +G VLC    CP + C +P      CCP+C   P    LS  +S 
Sbjct: 691 ETWNIDSCTQCTC-HSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSV 749

Query: 111 -------DGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQAS 163
                  +GDIF    + +          D   S  +      P     R  L   Q   
Sbjct: 750 PNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESC---PSVSCERPVLRKGQCCP 806

Query: 164 GTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHC 223
             I   +         VC  +GK Y+  E W        +  C  C C   +  C  + C
Sbjct: 807 YCIEDTIPKKV-----VCHFSGKAYADEERWD-------LDSCTHCYCLQGQTLCSTVSC 854

Query: 224 PNRYPCKYPQKIDGKCCKVCP 244
           P   PC  P  ++G CC +CP
Sbjct: 855 PP-LPCVEPINVEGSCCPMCP 874



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 8/64 (12%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C F  K Y   ERW        L  C +C C + G  LCS V CP + C+ P+++   CC
Sbjct: 819 CHFSGKAYADEERWD-------LDSCTHCYCLQ-GQTLCSTVSCPPLPCVEPINVEGSCC 870

Query: 97  PRCP 100
           P CP
Sbjct: 871 PMCP 874



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 9/63 (14%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           C +NG   +HG+ W  +       +C  C C   ++ C    C     C  P K+ G+CC
Sbjct: 403 CYANGLILAHGDRWRED-------DCTFCQCVNGERHCVATVCGQT--CTNPVKVPGECC 453

Query: 241 KVC 243
            VC
Sbjct: 454 PVC 456



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGD 102
           C  C C  NG  +C+ + CP   C +P   P  CCP C  D
Sbjct: 626 CRECYCL-NGREMCALITCPVPACGNPTIHPGQCCPSCADD 665



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 8/59 (13%)

Query: 44  YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGD 102
           +   E W P +       C +CIC ++  + C    CP+V C  PV     CCP C  D
Sbjct: 761 FLAAESWKPDV-------CTSCICIDSV-ISCFSESCPSVSCERPVLRKGQCCPYCIED 811



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 8/59 (13%)

Query: 185 GKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243
           G+ +  GE+W+       I  C  CTC+  +  C+   CP    C+ P +    CC  C
Sbjct: 684 GEYFVEGETWN-------IDSCTQCTCHSGRVLCETEVCPPLL-CQNPSRTQDSCCPQC 734



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 12/55 (21%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC----------PGDGELS 106
           C  C C  NG   C    C    C +PV +P  CCP C          P  GELS
Sbjct: 421 CTFCQCV-NGERHCVATVCGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELS 473


>gi|37693519 BMP-binding endothelial regulator precursor protein
           [Homo sapiens]
          Length = 685

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 25/215 (11%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL-- 94
           C+F+  +Y+ GE + P         C  C C+  G   C R  CP + C  P H+ H+  
Sbjct: 166 CVFEGVQYQEGEEFQPEGSK-----CTKCSCT-GGRTQCVREVCPILSC--PQHLSHIPP 217

Query: 95  --CCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSH 152
             CCP+C G  ++        +FR         S+   +      R +  + +     SH
Sbjct: 218 GQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGS-SFLYDNCTACTCRDSTVVCK--RKCSH 274

Query: 153 RGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN 212
            G     Q+  G   + ++    +  +VC    K +  GE W         + C +C C 
Sbjct: 275 PGGCDQGQE--GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSS-------INCTICACV 325

Query: 213 VTKQECKKIHCPNRYPCKYPQKIDGK-CCKVCPGK 246
             + EC+   C     C   + ++ K CC +C  K
Sbjct: 326 KGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 47/209 (22%), Positives = 76/209 (36%), Gaps = 29/209 (13%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C ++   Y    +W    EP  L  C   + +E+G      VRC  VHC +P+    +CC
Sbjct: 108 CTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESG------VRCV-VHCKNPLEHLGMCC 160

Query: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSH--RG 154
           P CPG      ++ +G+ F+   ++  + S           R+   +   P   SH   G
Sbjct: 161 PTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGR--TQCVREVCPILSCPQHLSHIPPG 218

Query: 155 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVT 214
                      +  +   +       C+     Y +G S       F    C  CTC  +
Sbjct: 219 QCCPKCLGQRKVFDLPFGS-------CLFRSDVYDNGSS-------FLYDNCTACTCRDS 264

Query: 215 KQECKKIHCPNRYPCKYPQKIDGKCCKVC 243
              CK+  C +   C   Q+    CC+ C
Sbjct: 265 TVVCKR-KCSHPGGCDQGQE---GCCEEC 289



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/205 (22%), Positives = 73/205 (35%), Gaps = 51/205 (24%)

Query: 62  CVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPA 119
           C+ C+C  N  V C R +CP +   C   +     CC +C G       ++    ++ PA
Sbjct: 67  CIMCVCL-NKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125

Query: 120 NREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQ 179
                        +P   RQ              G + +S    G    +   N  +H  
Sbjct: 126 -------------EPCVLRQC-----------QEGVVTES----GVRCVVHCKNPLEHLG 157

Query: 180 VC-------VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 232
           +C       V  G  Y  GE + P        +C  C+C   + +C +  CP       P
Sbjct: 158 MCCPTCPGCVFEGVQYQEGEEFQPEGS-----KCTKCSCTGGRTQCVREVCP---ILSCP 209

Query: 233 QKID----GKCCKVCPG-KKAKELP 252
           Q +     G+CC  C G +K  +LP
Sbjct: 210 QHLSHIPPGQCCPKCLGQRKVFDLP 234



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 23/86 (26%), Positives = 30/86 (34%), Gaps = 10/86 (11%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           C   G TY+    W           CVL  C         + C     CK P +  G CC
Sbjct: 108 CTYEGNTYNSSFKWQSPAEP-----CVLRQCQEGVVTESGVRCVVH--CKNPLEHLGMCC 160

Query: 241 KVCPG---KKAKELPGQSFDNKGYFC 263
             CPG   +  +   G+ F  +G  C
Sbjct: 161 PTCPGCVFEGVQYQEGEEFQPEGSKC 186


>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
          Length = 955

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 61/247 (24%), Positives = 89/247 (36%), Gaps = 52/247 (21%)

Query: 2   RKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDK--KYRVGERWHPYLEPYGL 59
           R++W++G  +  F            T Q     T C   D   ++ +G+ W P  +P   
Sbjct: 545 REEWRLGPGQCCF------------TCQEPTPSTGCSLDDNGVEFPIGQIWSPG-DP--- 588

Query: 60  VYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPA 119
             C  CIC  +G+V C R  C +  C  P+ IP  CCP C      +     G IF    
Sbjct: 589 --CELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDCSAGCTYT-----GRIF---- 636

Query: 120 NREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNK-HKHG 178
                  Y+   +   PS     LS           L+ S   S     I      H  G
Sbjct: 637 -------YNNETF---PSVLDPCLSCI--------CLLGSVACSPVDCPITCTYPFHPDG 678

Query: 179 QVC-VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDG 237
           + C V     Y   +  +  +       C  CTC + +  C+K+ C  +  C  P  + G
Sbjct: 679 ECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEKVPC--QRACADPALLPG 736

Query: 238 KCCKVCP 244
            CC  CP
Sbjct: 737 DCCSSCP 743



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/203 (25%), Positives = 72/203 (35%), Gaps = 36/203 (17%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL---CCPRCPGDGELSWEHSDGDIFRQP 118
           C  C C E+G V C +VRC    C  P  IP     CCP C G        ++GD+F  P
Sbjct: 404 CSQCWC-EDGKVTCEKVRC-EAACSHP--IPSRDGGCCPSCTGCFHSGVVRAEGDVF-SP 458

Query: 119 ANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHG 178
            N                   AG +S               Q    T V +         
Sbjct: 459 PNENCTVCV----------CLAGNVSCISPECPSGPCQTPPQTDCCTCVPV--------- 499

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPN-RYPCKYPQKIDG 237
             C  +G+ Y+ G  +     + G  EC  C C   + EC  + CP    P +  +   G
Sbjct: 500 -RCYFHGRWYADGAVF-----SGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPG 553

Query: 238 KCCKVCPGKKAKELPGQSFDNKG 260
           +CC  C  ++     G S D+ G
Sbjct: 554 QCCFTC--QEPTPSTGCSLDDNG 574


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 12/80 (15%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           C  NG+ Y + + W P         C +C C+     C KI C +   C  P    G+CC
Sbjct: 41  CTQNGQMYLNRDIWKP-------APCQICVCDNGAILCDKIECQDVLDCADPVTPPGECC 93

Query: 241 KVCPGKKAKELPGQSFDNKG 260
            VC      + PG    N G
Sbjct: 94  PVC-----SQTPGGGNTNFG 108



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 12/78 (15%)

Query: 34  ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNV-HCLSPVHIP 92
           E  C    + Y   + W P         C  C+C +NG +LC ++ C +V  C  PV  P
Sbjct: 38  EIACTQNGQMYLNRDIWKP-------APCQICVC-DNGAILCDKIECQDVLDCADPVTPP 89

Query: 93  HLCCPRC---PGDGELSW 107
             CCP C   PG G  ++
Sbjct: 90  GECCPVCSQTPGGGNTNF 107


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           CV NG  Y   + W P         C +C C+  K  C  + C     C   +  +G+CC
Sbjct: 40  CVQNGLRYHDRDVWKPE-------PCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECC 92

Query: 241 KVCP 244
            VCP
Sbjct: 93  PVCP 96



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 9/69 (13%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH-LC 95
           C+    +Y   + W P  EP     C  C+C +NG VLC  V C          +P   C
Sbjct: 40  CVQNGLRYHDRDVWKP--EP-----CRICVC-DNGKVLCDDVICDETKNCPGAEVPEGEC 91

Query: 96  CPRCPGDGE 104
           CP CP   E
Sbjct: 92  CPVCPDGSE 100


>gi|122937446 von Willebrand factor C domain-containing protein
           2-like [Homo sapiens]
          Length = 222

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 7/75 (9%)

Query: 25  GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84
           G   + K  + +C +  K Y++ E + P   P     C  C C  +  V C    C    
Sbjct: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156

Query: 85  CLSPVHIPHLCCPRC 99
           C++PV+ P  CCP C
Sbjct: 157 CVNPVYEPEQCCPVC 171


>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
          Length = 1170

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%)

Query: 173 NKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 232
           N+ +   +C  NG  Y + E W        +  C  C C  +   CKK+ CP   PC   
Sbjct: 310 NELRRPPLCYHNGVQYRNNEEWT-------VDSCTECHCQNSVTICKKVSCP-IMPCSNA 361

Query: 233 QKIDGKCCKVC 243
              DG+CC  C
Sbjct: 362 TVPDGECCPRC 372



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 9/67 (13%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
           C     +YR  E W        +  C  C C +N   +C +V CP + C +       CC
Sbjct: 318 CYHNGVQYRNNEEWT-------VDSCTECHC-QNSVTICKKVSCPIMPCSNATVPDGECC 369

Query: 97  PRC-PGD 102
           PRC P D
Sbjct: 370 PRCWPSD 376


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 7/64 (10%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
           CV +G+ Y+  + W P         C +C C+     C  I C +   C  P+   G+CC
Sbjct: 34  CVQDGQRYNDKDVWKPE-------PCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECC 86

Query: 241 KVCP 244
            +CP
Sbjct: 87  PICP 90



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 9/67 (13%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPVHIPHLC 95
           C+   ++Y   + W P  EP     C  C+C + G VLC  + C +V  CLSP      C
Sbjct: 34  CVQDGQRYNDKDVWKP--EP-----CRICVC-DTGTVLCDDIICEDVKDCLSPEIPFGEC 85

Query: 96  CPRCPGD 102
           CP CP D
Sbjct: 86  CPICPTD 92


>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
          Length = 1172

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 8/70 (11%)

Query: 174 KHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQ 233
           K ++   C  +G+ ++  E+W        +  C  CTC   K  C +I CP    C  P 
Sbjct: 313 KTRNMSACWQDGRFFAENETWV-------VDSCTTCTCKKFKTICHQITCPPA-TCASPS 364

Query: 234 KIDGKCCKVC 243
            ++G+CC  C
Sbjct: 365 FVEGECCPSC 374



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 3/48 (6%)

Query: 62  CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC--PGDGELSW 107
           C  C C +    +C ++ CP   C SP  +   CCP C    DGE  W
Sbjct: 338 CTTCTCKKF-KTICHQITCPPATCASPSFVEGECCPSCLHSVDGEEGW 384


>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
          Length = 839

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236
           + C   G TY   ESW        I  C  CTC     +C+ + CPN   P K     +D
Sbjct: 295 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 346

Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273
           GKCCK C  K   +  G++         + + G    Y C ++TM + ES
Sbjct: 347 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 394



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 37  CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+ +  Y  G+ W        +  C  C C + G V C  + CP+V C   +   + 
Sbjct: 723 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 773

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 774 CCPRCVTD 781



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
           + E  C  +   YR  E W        +  C NC C  NG + C  + CPN  C    + 
Sbjct: 292 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 342

Query: 89  VHIPHLCCPRC 99
            ++   CC  C
Sbjct: 343 AYVDGKCCKEC 353



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
           K  ++ C FQ + Y  GER   Y        CV   C +    L     CP + C     
Sbjct: 351 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 407

Query: 89  VHIPHLCCPRCPGDGELSWEHS 110
           + + H CC  C G    S  H+
Sbjct: 408 ITLSHSCCKVCKGYDFCSERHN 429



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)

Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233
           +C   G+TY  GE  +    + G+  CVL  C       V    C  + CP  +      
Sbjct: 356 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 409

Query: 234 KIDGKCCKVCPG 245
            +   CCKVC G
Sbjct: 410 -LSHSCCKVCKG 420


>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
          Length = 815

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236
           + C   G TY   ESW        I  C  CTC     +C+ + CPN   P K     +D
Sbjct: 271 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 322

Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273
           GKCCK C  K   +  G++         + + G    Y C ++TM + ES
Sbjct: 323 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 370



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 37  CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+ +  Y  G+ W        +  C  C C + G V C  + CP+V C   +   + 
Sbjct: 699 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 749

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 750 CCPRCVTD 757



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
           + E  C  +   YR  E W        +  C NC C  NG + C  + CPN  C    + 
Sbjct: 268 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 318

Query: 89  VHIPHLCCPRC 99
            ++   CC  C
Sbjct: 319 AYVDGKCCKEC 329



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
           K  ++ C FQ + Y  GER   Y        CV   C +    L     CP + C     
Sbjct: 327 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 383

Query: 89  VHIPHLCCPRCPGDGELSWEHS 110
           + + H CC  C G    S  H+
Sbjct: 384 ITLSHSCCKVCKGYDFCSERHN 405



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)

Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233
           +C   G+TY  GE  +    + G+  CVL  C       V    C  + CP  +      
Sbjct: 332 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 385

Query: 234 KIDGKCCKVCPG 245
            +   CCKVC G
Sbjct: 386 -LSHSCCKVCKG 396


>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236
           + C   G TY   ESW        I  C  CTC     +C+ + CPN   P K     +D
Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323

Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273
           GKCCK C  K   +  G++         + + G    Y C ++TM + ES
Sbjct: 324 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 37  CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+ +  Y  G+ W        +  C  C C + G V C  + CP+V C   +   + 
Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 751 CCPRCVTD 758



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
           + E  C  +   YR  E W        +  C NC C  NG + C  + CPN  C    + 
Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319

Query: 89  VHIPHLCCPRC 99
            ++   CC  C
Sbjct: 320 AYVDGKCCKEC 330



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
           K  ++ C FQ + Y  GER   Y        CV   C +    L     CP + C     
Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384

Query: 89  VHIPHLCCPRCPGDGELSWEHS 110
           + + H CC  C G    S  H+
Sbjct: 385 ITLSHSCCKVCKGYDFCSERHN 406



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)

Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233
           +C   G+TY  GE  +    + G+  CVL  C       V    C  + CP  +      
Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386

Query: 234 KIDGKCCKVCPG 245
            +   CCKVC G
Sbjct: 387 -LSHSCCKVCKG 397


>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
          Length = 866

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236
           + C   G TY   ESW        I  C  CTC     +C+ + CPN   P K     +D
Sbjct: 322 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 373

Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273
           GKCCK C  K   +  G++         + + G    Y C ++TM + ES
Sbjct: 374 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 421



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 37  CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+ +  Y  G+ W        +  C  C C + G V C  + CP+V C   +   + 
Sbjct: 750 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 800

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 801 CCPRCVTD 808



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
           + E  C  +   YR  E W        +  C NC C  NG + C  + CPN  C    + 
Sbjct: 319 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 369

Query: 89  VHIPHLCCPRC 99
            ++   CC  C
Sbjct: 370 AYVDGKCCKEC 380



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
           K  ++ C FQ + Y  GER   Y        CV   C +    L     CP + C     
Sbjct: 378 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 434

Query: 89  VHIPHLCCPRCPGDGELSWEHS 110
           + + H CC  C G    S  H+
Sbjct: 435 ITLSHSCCKVCKGYDFCSERHN 456



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)

Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233
           +C   G+TY  GE  +    + G+  CVL  C       V    C  + CP  +      
Sbjct: 383 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 436

Query: 234 KIDGKCCKVCPG 245
            +   CCKVC G
Sbjct: 437 -LSHSCCKVCKG 447


>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 25/110 (22%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 236
           + C   G TY   ESW        I  C  CTC     +C+ + CPN   P K     +D
Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323

Query: 237 GKCCKVCPGKKAKELPGQS---------FDNKG----YFCGEETMPVYES 273
           GKCCK C  K   +  G++         + + G    Y C ++TM + ES
Sbjct: 324 GKCCKEC--KSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 37  CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+ +  Y  G+ W        +  C  C C + G V C  + CP+V C   +   + 
Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 751 CCPRCVTD 758



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 12/71 (16%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
           + E  C  +   YR  E W        +  C NC C  NG + C  + CPN  C    + 
Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319

Query: 89  VHIPHLCCPRC 99
            ++   CC  C
Sbjct: 320 AYVDGKCCKEC 330



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 31  KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
           K  ++ C FQ + Y  GER   Y        CV   C +    L     CP + C     
Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384

Query: 89  VHIPHLCCPRCPGDGELSWEHS 110
           + + H CC  C G    S  H+
Sbjct: 385 ITLSHSCCKVCKGYDFCSERHN 406



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)

Query: 180 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 233
           +C   G+TY  GE  +    + G+  CVL  C       V    C  + CP  +      
Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386

Query: 234 KIDGKCCKVCPG 245
            +   CCKVC G
Sbjct: 387 -LSHSCCKVCKG 397


>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
          Length = 763

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 236
           + C  +G  Y   +SW           C  CTC     EC+++ CP  N  P   P  I 
Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324

Query: 237 GKCCKVCPGK 246
           G+CCKVC  K
Sbjct: 325 GQCCKVCRPK 334



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 10/71 (14%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88
           H E  C      YR  + W          +C NC C ++G V C R+ CP ++C     P
Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320

Query: 89  VHIPHLCCPRC 99
           VHI   CC  C
Sbjct: 321 VHIAGQCCKVC 331



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%)

Query: 37  CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+  K YR G+ W           C  C C E G V C  + CPN+ C     +   
Sbjct: 647 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 697

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 698 CCPRCVSD 705



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%)

Query: 186 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243
           K Y  G++W  +        C  C C   + +C  + CPN   C+Y   ++G+CC  C
Sbjct: 654 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 702


>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
          Length = 810

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%)

Query: 179 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 236
           + C  +G  Y   +SW           C  CTC     EC+++ CP  N  P   P  I 
Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324

Query: 237 GKCCKVCPGK 246
           G+CCKVC  K
Sbjct: 325 GQCCKVCRPK 334



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 10/71 (14%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88
           H E  C      YR  + W          +C NC C ++G V C R+ CP ++C     P
Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320

Query: 89  VHIPHLCCPRC 99
           VHI   CC  C
Sbjct: 321 VHIAGQCCKVC 331



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%)

Query: 37  CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
           C+ Q+  K YR G+ W           C  C C E G V C  + CPN+ C     +   
Sbjct: 694 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 744

Query: 95  CCPRCPGD 102
           CCPRC  D
Sbjct: 745 CCPRCVSD 752



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%)

Query: 186 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243
           K Y  G++W  +        C  C C   + +C  + CPN   C+Y   ++G+CC  C
Sbjct: 701 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 749


>gi|108773804 Fraser syndrome 1 [Homo sapiens]
          Length = 4011

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 62/269 (23%), Positives = 87/269 (32%), Gaps = 64/269 (23%)

Query: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP---VHIPH 93
           C ++   ++ GE W        L  C  C+C  NG   C   +C  + C      V +P 
Sbjct: 159 CSYEGHVFQDGEDWR-------LSRCAKCLC-RNGVAQCFTAQCQPLFCNQDETVVRVPG 210

Query: 94  LCCPR-----CPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDP-PPSRQAGGLSRFP 147
            CCP+     C   G++ +EH +                 R H     P R   G SR  
Sbjct: 211 KCCPQCSARSCSAAGQV-YEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSR-- 267

Query: 148 GARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECV 207
            AR H     +    +G+               C  +G      E W  +   F + +  
Sbjct: 268 -ARRHGQCCEECVSPAGS---------------CSYDGVVRYQDEMWKGSACEFCMCDHG 311

Query: 208 LCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEET 267
             TC     EC K+ C       +   +DGKCC  C                GY   EET
Sbjct: 312 QVTCQT--GECAKVECARDEELIH---LDGKCCPEC------------ISRNGYCVYEET 354

Query: 268 MPVYESVFMEDGETTRKIALETERPPQVE 296
                      GE     A E +R P+ E
Sbjct: 355 -----------GEFMSSNASEVKRIPEGE 372



 Score = 36.6 bits (83), Expect = 0.038
 Identities = 51/244 (20%), Positives = 74/244 (30%), Gaps = 53/244 (21%)

Query: 32  HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH- 90
           HSE  C++QD        W P         C +C C     V+C    C N  C      
Sbjct: 23  HSEGACVYQDSLLADATIWKP-------DSCQSCRC-HGDIVICKPAVCRNPQCAFEKGE 74

Query: 91  ----IPHLCCPRC----PGD---GELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQ 139
                 + CCP C    PG     +   EH         +     H   R    P P   
Sbjct: 75  VLQIAANQCCPECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLS 134

Query: 140 AG--GLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPN 197
            G   L+  P                G+   + +      G+ C   G  +  GE W   
Sbjct: 135 CGHQELAFIP---------------EGSCCPVCVG----LGKPCSYEGHVFQDGEDWR-- 173

Query: 198 LRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQ---KIDGKCCKVCPGKKAKELPGQ 254
                +  C  C C     +C    C   + C   +   ++ GKCC  C  +      GQ
Sbjct: 174 -----LSRCAKCLCRNGVAQCFTAQCQPLF-CNQDETVVRVPGKCCPQCSARSC-SAAGQ 226

Query: 255 SFDN 258
            +++
Sbjct: 227 VYEH 230


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 181  CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
            CV  G     GES H N   +    C +C C   +  C    CP    C  P  I G CC
Sbjct: 1415 CVDAG-----GES-HANNTKWKKDACTICECKDGQVTCFVEACPPA-TCAVPVNIPGACC 1467

Query: 241  KVCPGKKAKELP 252
             VC  K+A+E P
Sbjct: 1468 PVCLQKRAEEKP 1479



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

Query: 62   CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99
            C  C C + G V C    CP   C  PV+IP  CCP C
Sbjct: 1434 CTICECKD-GQVTCFVEACPPATCAVPVNIPGACCPVC 1470


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 62   CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDG 103
            C +CIC E+G V C    CP   C SP  +   CCP C   G
Sbjct: 1414 CTHCIC-ESGQVTCVVEICPPAPCPSPELVKGTCCPVCRDRG 1454



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%)

Query: 205  ECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 243
            +C  C C   +  C    CP   PC  P+ + G CC VC
Sbjct: 1413 DCTHCICESGQVTCVVEICPPA-PCPSPELVKGTCCPVC 1450


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 8/65 (12%)

Query: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQKIDGKC 239
           C   G++Y+  + W P         C +C C+     C  I C ++   C  P+   G+C
Sbjct: 32  CSHLGQSYADRDVWKPE-------PCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGEC 84

Query: 240 CKVCP 244
           C VCP
Sbjct: 85  CAVCP 89


>gi|188497705 BRCA1 associated protein [Homo sapiens]
          Length = 592

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 27/141 (19%), Positives = 62/141 (43%), Gaps = 11/141 (7%)

Query: 238 KCCKVCPGKKAKELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEV 297
           +C    P   +K+LP    D   +F G  ++ +   + M   +T +  +L+ +      +
Sbjct: 109 ECINAAPDSPSKQLP----DQISFFSGNPSVEIVHGI-MHLYKTNKMTSLKEDVRRSAML 163

Query: 298 HVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQIS-----QMCS 352
            + T+   +  H  + K      E +   K++  +T +Q+ +  +  AQ         C+
Sbjct: 164 CILTVPAAMTSH-DLMKFVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCN 222

Query: 353 SRVCRTELEDLVKVLYLERSE 373
            R   +  +D+ +++Y+ER+E
Sbjct: 223 GRQFNSIEDDVCQLVYVERAE 243


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,696,574
Number of Sequences: 37866
Number of extensions: 900628
Number of successful extensions: 2462
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2198
Number of HSP's gapped (non-prelim): 211
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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