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Search of human proteins with 221316563
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 993 0.0
gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 988 0.0
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 986 0.0
gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] 626 e-179
gi|40353769 chordin-like 2 [Homo sapiens] 311 8e-85
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 104 1e-22
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 103 4e-22
gi|37693519 BMP-binding endothelial regulator precursor protein ... 95 1e-19
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 95 2e-19
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 77 3e-14
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa... 76 7e-14
gi|30089980 chordin [Homo sapiens] 74 3e-13
gi|108773804 Fraser syndrome 1 [Homo sapiens] 71 2e-12
gi|122937446 von Willebrand factor C domain-containing protein 2... 69 1e-11
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 60 3e-09
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 60 3e-09
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 59 9e-09
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 59 9e-09
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 59 9e-09
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 59 9e-09
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 59 9e-09
gi|109150416 peroxidasin [Homo sapiens] 54 2e-07
gi|126517478 peroxidasin homolog-like [Homo sapiens] 46 8e-05
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 45 1e-04
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 45 1e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 44 3e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 44 3e-04
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 44 3e-04
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 44 4e-04
gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] 42 0.001
>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
Length = 457
Score = 993 bits (2567), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGT 120
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGT
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGT 120
Query: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG
Sbjct: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Query: 181 DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQ 240
DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQ
Sbjct: 181 DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQ 240
Query: 241 ASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKI 300
ASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKI
Sbjct: 241 ASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKI 300
Query: 301 HCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGE 360
HCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGE
Sbjct: 301 HCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGE 360
Query: 361 TTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIF 420
TTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIF
Sbjct: 361 TTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIF 420
Query: 421 TEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 457
TEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC
Sbjct: 421 TEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 457
>gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
Length = 458
Score = 988 bits (2555), Expect = 0.0
Identities = 457/458 (99%), Positives = 457/458 (99%), Gaps = 1/458 (0%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP-DSLPPVNNKVTSKSCEYNG 119
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP DSLPPVNNKVTSKSCEYNG
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG 120
Query: 120 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR
Sbjct: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
Query: 180 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 239
GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ
Sbjct: 181 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 240
Query: 240 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 299
QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK
Sbjct: 241 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 300
Query: 300 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 359
IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG
Sbjct: 301 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 360
Query: 360 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 419
ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI
Sbjct: 361 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 420
Query: 420 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 457
FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC
Sbjct: 421 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 458
>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
Length = 456
Score = 986 bits (2550), Expect = 0.0
Identities = 456/457 (99%), Positives = 456/457 (99%), Gaps = 1/457 (0%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGT 120
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGT
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGT 120
Query: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG
Sbjct: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Query: 181 DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQ 240
DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQ
Sbjct: 181 DGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQ 240
Query: 241 ASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKI 300
ASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKI
Sbjct: 241 ASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKI 300
Query: 301 HCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGE 360
HCPNRYPCKYPQKIDGKCCKVCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGE
Sbjct: 301 HCPNRYPCKYPQKIDGKCCKVCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGE 359
Query: 361 TTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIF 420
TTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIF
Sbjct: 360 TTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIF 419
Query: 421 TEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 457
TEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC
Sbjct: 420 TEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 456
>gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]
Length = 377
Score = 626 bits (1615), Expect = e-179
Identities = 295/317 (93%), Positives = 297/317 (93%), Gaps = 2/317 (0%)
Query: 142 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 200
C C CSE GNV C CP + C PV +P CC C GDGELSWEHSDGDIFRQPANR
Sbjct: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121
Query: 201 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 260
EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC
Sbjct: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181
Query: 261 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 320
VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK
Sbjct: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241
Query: 321 VCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 380
VCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW
Sbjct: 242 VCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300
Query: 381 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 440
TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL
Sbjct: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360
Query: 441 EDLVKVLYLERSEKGHC 457
EDLVKVLYLERSEKGHC
Sbjct: 361 EDLVKVLYLERSEKGHC 377
Score = 236 bits (602), Expect = 3e-62
Identities = 125/245 (51%), Positives = 140/245 (57%), Gaps = 65/245 (26%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDS-------------LPPVN 107
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP P N
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120
Query: 108 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 127
+ S + +GT Q HG++
Sbjct: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180
Query: 128 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 175
V+ G ++ PN +C C+C+ C CP + C +P + CC
Sbjct: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
Query: 176 RVCRG 180
+VC G
Sbjct: 241 KVCPG 245
Score = 60.1 bits (144), Expect = 4e-09
Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 255 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 312
KH + C+ K Y GE WHP L +G+V CV C C+ C ++ CPN + C P
Sbjct: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89
Query: 313 KIDGKCCKVCPG 324
I CC CPG
Sbjct: 90 HIPHLCCPRCPG 101
>gi|40353769 chordin-like 2 [Homo sapiens]
Length = 451
Score = 311 bits (797), Expect = 8e-85
Identities = 148/360 (41%), Positives = 200/360 (55%), Gaps = 25/360 (6%)
Query: 34 ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH 93
+ +C+F K+Y GE WHPYLEP GL+YC+ C CSE +V C R+ CP VHC PV P
Sbjct: 30 DMFCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQ 89
Query: 94 LCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVY 153
CCP+C + P + KSC++NGT YQHGE+F A LF +R PNQC CSC+EG +Y
Sbjct: 90 QCCPKCVEPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIY 149
Query: 154 CGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDP 213
CGL TCP+ C P+ +PDSCC+ C+ + E SD ++ S H +
Sbjct: 150 CGLTTCPEPGCPAPLPLPDSCCQACKDEAS---EQSD--------EEDSVQSLHGVRHPQ 198
Query: 214 PPSRQAGGLSRFPGARSHRGAL---------MDSQQASGTIVQIVINNKHKHGQVCVSNG 264
P G R PG + G + A T V+IV+ KHK + CV G
Sbjct: 199 DPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHK--KACVHGG 256
Query: 265 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 324
KTYSHGE WHP RAFG + C+LCTC +Q+C+++ CP YPC++P+K+ GKCCK+CP
Sbjct: 257 KTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKICPE 316
Query: 325 KKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWTIRK 384
KA PG S + + + + R+ ALE E VE+++W + K
Sbjct: 317 DKAD---PGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEASDLVEIYLWKLVK 373
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 104 bits (260), Expect = 1e-22
Identities = 84/300 (28%), Positives = 106/300 (35%), Gaps = 61/300 (20%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 424 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 477
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P C SC Y+ Y +G+ F + C C C +G V C L
Sbjct: 478 PSCD-------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCSL 517
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDP 213
CP TCA P S P CC C D L E DG+ F P + +E R +H P
Sbjct: 518 VDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQP 576
Query: 214 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW 273
P +A PG SG C GK Y G +
Sbjct: 577 RPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGADF 613
Query: 274 -HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELP 332
HP+ C LC C +C C PC P + G+CC CP A P
Sbjct: 614 PHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPAPAGCP 666
Score = 96.7 bits (239), Expect = 4e-20
Identities = 78/293 (26%), Positives = 106/293 (36%), Gaps = 68/293 (23%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + Y GE + P C C C E G + C++ CP C P CC
Sbjct: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPRGPCPEP----GACC 185
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P C C+Y G Y+ G F++ N C QC+C V C
Sbjct: 186 PHC------------KPGCDYEGQLYEEGVTFLSSS-------NPCLQCTCLRSRVRCMA 226
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 214
CP C PV P CC C+G +G WEH G + P + R +
Sbjct: 227 LKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQC 283
Query: 215 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE--- 271
R+ L +P ++ GT + C NG+ + GE
Sbjct: 284 RQRECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVG 324
Query: 272 SWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 324
S P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 325 SGDP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367
Score = 89.4 bits (220), Expect = 6e-18
Identities = 88/312 (28%), Positives = 120/312 (38%), Gaps = 60/312 (19%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361
Query: 96 CPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 155
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 362 CPVCD-------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSCE 402
Query: 156 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 215
+ CP CA P S C C DGE E ++G + +P R + D P
Sbjct: 403 EQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP 454
Query: 216 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHP 275
+ G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 455 --KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS--- 501
Query: 276 NLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE--LPG 333
C C C C + CP C PQ G+CC CP +EE + G
Sbjct: 502 --------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDG 552
Query: 334 QSFDNKGYFCGE 345
+SF + C E
Sbjct: 553 ESFSHPRDPCQE 564
Score = 82.4 bits (202), Expect = 8e-16
Identities = 74/342 (21%), Positives = 119/342 (34%), Gaps = 99/342 (28%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHI 91
H + C ++ + Y G + P C+ C C + V C ++CP C PV
Sbjct: 187 HCKPGCDYEGQLYEEGVTFLSSSNP-----CLQCTCLRS-RVRCMALKCPPSPCPEPVLR 240
Query: 92 PHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELF----------------------- 128
P CCP C + C G+ ++HG+ +
Sbjct: 241 PGHCCPTC-------------QGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 287
Query: 129 ------------------VAEGLFQNRQPNQ----------CTQCSCSEGNVYCGLKTCP 160
V +G F N + ++ C+ C C+ G+V C CP
Sbjct: 288 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 347
Query: 161 KLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAG 220
+ C P +P CC VC G ++ + FR + R R S QAG
Sbjct: 348 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAG 397
Query: 221 GLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAF 280
+S + Q+ T + + + + C +G+ ++ G W P+ R
Sbjct: 398 EVS------------CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-- 442
Query: 281 GIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
C C C +C + CP PC++P + G CC C
Sbjct: 443 ---PCTACVCQDGVPKCGAVLCPPA-PCQHPTQPPGACCPSC 480
Score = 73.2 bits (178), Expect = 5e-13
Identities = 67/291 (23%), Positives = 97/291 (33%), Gaps = 80/291 (27%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + G RW P C C+C + HC H+PH
Sbjct: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
+ C NG TY +GE F P+ CT C C EG + C
Sbjct: 136 ----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLEGTITCNQ 170
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPS 216
K CP+ C P + C C +G+L + +G F +N + + RS
Sbjct: 171 KPCPRGPCPEPGACCPHCKPGCDYEGQL---YEEGVTFLSSSNPCLQCTCLRS------- 220
Query: 217 RQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESWH 274
R M + + V+ H Q C G + HG+ W
Sbjct: 221 ---------------RVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW- 264
Query: 275 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 324
C +C C +C++ C + C YP + + G CC VC G
Sbjct: 265 ----TTPGDPCRICRCLEGHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309
Score = 72.0 bits (175), Expect = 1e-12
Identities = 80/347 (23%), Positives = 108/347 (31%), Gaps = 107/347 (30%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + Y G+ + P C C C ++G V CS V CP C P P CC
Sbjct: 483 CTYHSQVYANGQNFTDADSP-----CHACHC-QDGTVTCSLVDCPPTTCARPQSGPGQCC 536
Query: 97 PRCPDSLPPVNNKVTSKS------------------------------------------ 114
PRCPD + V +S
Sbjct: 537 PRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPND 596
Query: 115 ---CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP 171
C + G Y G F + C C C GNV C + C L C PV +P
Sbjct: 597 CSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLP 649
Query: 172 DSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP--PSRQA----GGLS-- 223
CC C + G A H+ H+ ++ PP P R+ G +S
Sbjct: 650 GECCPQCPAAPAPAGCPRPG----------AAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 699
Query: 224 -----RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLR 278
P A +G S C+ GK ++ GE +
Sbjct: 700 RLPCPPAPCAHPRQGPCCPSCDG------------------CLYQGKEFASGERFPSPTA 741
Query: 279 AFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGK 325
A C LC C C+ C C +P + G CC C G+
Sbjct: 742 A-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCDGE 780
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 103 bits (256), Expect = 4e-22
Identities = 82/291 (28%), Positives = 104/291 (35%), Gaps = 61/291 (20%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 366 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 419
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P C SC Y+ Y +G+ F + C C C +G V C L
Sbjct: 420 PSCD-------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCSL 459
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYDP 213
CP TCA P S P CC C D L E DG+ F P + +E R +H P
Sbjct: 460 VDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQP 518
Query: 214 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW 273
P +A PG SG C GK Y G +
Sbjct: 519 RPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGADF 555
Query: 274 -HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCP 323
HP+ C LC C +C C PC P + G+CC CP
Sbjct: 556 PHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCP 599
Score = 89.4 bits (220), Expect = 6e-18
Identities = 88/312 (28%), Positives = 120/312 (38%), Gaps = 60/312 (19%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 252 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 303
Query: 96 CPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 155
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 304 CPVCD-------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSCE 344
Query: 156 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 215
+ CP CA P S C C DGE E ++G + +P R + D P
Sbjct: 345 EQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGVP 396
Query: 216 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHP 275
+ G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 397 --KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS--- 443
Query: 276 NLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE--LPG 333
C C C C + CP C PQ G+CC CP +EE + G
Sbjct: 444 --------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVDG 494
Query: 334 QSFDNKGYFCGE 345
+SF + C E
Sbjct: 495 ESFSHPRDPCQE 506
Score = 89.0 bits (219), Expect = 8e-18
Identities = 72/291 (24%), Positives = 101/291 (34%), Gaps = 80/291 (27%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + G RW P C C+C + HC H+PH
Sbjct: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
+ C NG TY +GE F P+ CT C C G V C
Sbjct: 136 ----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLTGAVQCQG 170
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPS 216
+C +L C + P CC +C +G WEH G + P + R +
Sbjct: 171 PSCSELNCLESCTPPGECCPICCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQCRQ 227
Query: 217 RQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE---SW 273
R+ L +P ++ GT + C NG+ + GE S
Sbjct: 228 RECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVGSG 268
Query: 274 HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 324
P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 269 DP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 309
Score = 81.6 bits (200), Expect = 1e-15
Identities = 70/277 (25%), Positives = 107/277 (38%), Gaps = 58/277 (20%)
Query: 47 GERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH-IPHLCCPRCPDSLPP 105
G+ W +P C C C E G++ C + C ++ C P +P CCP C
Sbjct: 203 GQEWTTPGDP-----CRICRCLE-GHIQCRQRECASL-CPYPARPLPGTCCPVCD----- 250
Query: 106 VNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCA 165
C NG ++ GE V G + C+ C C+ G+V C CP + C
Sbjct: 251 --------GCFLNGREHRSGEP-VGSG-------DPCSHCRCANGSVQCEPLPCPPVPCR 294
Query: 166 FPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF 225
P +P CC VC G ++ + FR + R R S QAG +S
Sbjct: 295 HPGKIPGQCCPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS-- 342
Query: 226 PGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVEC 285
+ Q+ T + + + + C +G+ ++ G W P+ R C
Sbjct: 343 ----------CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----PC 386
Query: 286 VLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
C C +C + CP PC++P + G CC C
Sbjct: 387 TACVCQDGVPKCGAVLCPPA-PCQHPTQPPGACCPSC 422
Score = 75.5 bits (184), Expect = 9e-14
Identities = 73/311 (23%), Positives = 107/311 (34%), Gaps = 73/311 (23%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + Y + + EP L C+ G V C R C C P+ CC
Sbjct: 719 CEYLGESYLSNQEFPDPREPCNLCTCLG------GFVTCGRRPCEPPGCSHPLIPSGHCC 772
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P C + C Y+G T GE + C+ C+C EG++ C
Sbjct: 773 PTC-------------QGCRYHGVTTASGETL------PDPLDPTCSLCTCQEGSMRCQK 813
Query: 157 KTCPKLTCAFPVSVPDSC--CRVCRGDGELSWEHSDGDIFRQPAN-------REARHSYH 207
K CP C P P C C C G EH DG+ F PA + + S
Sbjct: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGR---EHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
Query: 208 RSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTY 267
R P P + + RG+ + C+++G+ +
Sbjct: 871 RLQCPPLPCKL---------QVTERGSCCPRCRG------------------CLAHGEEH 903
Query: 268 SHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG--K 325
G W P A C C C+ C +I C + C P++ CC C
Sbjct: 904 PEGSRWVPPDSA-----CSSCVCHEGVVTCARIQCIS--SCAQPRQGPHDCCPQCSDCEH 956
Query: 326 KAKEELPGQSF 336
+ ++ PG+SF
Sbjct: 957 EGRKYEPGESF 967
Score = 74.3 bits (181), Expect = 2e-13
Identities = 73/299 (24%), Positives = 103/299 (34%), Gaps = 64/299 (21%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C++Q K++ GER+ P C C+C E G+V C C C P CC
Sbjct: 662 CLYQGKEFASGERF-----PSPTAACHLCLCWE-GSVSCEPKACAPALCPFPARGD--CC 713
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P C CEY G +Y + F R+P C C+C G V CG
Sbjct: 714 PDCD-------------GCEYLGESYLSNQEFP-----DPREP--CNLCTCLGGFVTCGR 753
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR-----EARHSYHRSHY 211
+ C C+ P+ CC C+G + G+ P + + R
Sbjct: 754 RPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQK 813
Query: 212 DPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE 271
P P P H + G V ++ C+S G+ + GE
Sbjct: 814 KPCP----------PALCPH--------PSPGPCFCPVCHS-------CLSQGREHQDGE 848
Query: 272 SWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE 330
+ + C C C + C ++ CP PCK G CC C G A E
Sbjct: 849 EFEGPAGS-----CEWCRCQAGQVSCVRLQCP-PLPCKLQVTERGSCCPRCRGCLAHGE 901
Score = 72.0 bits (175), Expect = 1e-12
Identities = 81/307 (26%), Positives = 98/307 (31%), Gaps = 74/307 (24%)
Query: 49 RWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNN 108
R Y P G C C+C + G+V C R+ CP C P P CCP C
Sbjct: 613 RHQEYFSPPGDP-CRRCLCLD-GSVSCQRLPCPPAPCAHPRQGP--CCPSCD-------- 660
Query: 109 KVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPV 168
C Y G + GE F + C C C EG+V C K C C FP
Sbjct: 661 -----GCLYQGKEFASGERFPSPTA-------ACHLCLCWEGSVSCEPKACAPALCPFPA 708
Query: 169 SVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF--- 225
CC C G L + F P P L F
Sbjct: 709 R--GDCCPDCDGCEYLGESYLSNQEFPDPRE---------------PCNLCTCLGGFVTC 751
Query: 226 ------PGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRA 279
P SH L+ S T Q C +G T + GE+ L
Sbjct: 752 GRRPCEPPGCSH--PLIPSGHCCPTC------------QGCRYHGVTTASGETLPDPLDP 797
Query: 280 FGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKC-CKVCPG--KKAKEELPGQSF 336
C LCTC C+K CP P P G C C VC + +E G+ F
Sbjct: 798 ----TCSLCTCQEGSMRCQKKPCP---PALCPHPSPGPCFCPVCHSCLSQGREHQDGEEF 850
Query: 337 DNKGYFC 343
+ C
Sbjct: 851 EGPAGSC 857
Score = 71.6 bits (174), Expect = 1e-12
Identities = 80/346 (23%), Positives = 107/346 (30%), Gaps = 110/346 (31%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + Y G+ + P C C C ++G V CS V CP C P P CC
Sbjct: 425 CTYHSQVYANGQNFTDADSP-----CHACHC-QDGTVTCSLVDCPPTTCARPQSGPGQCC 478
Query: 97 PRCPDSLPPVNNKVTSKS------------------------------------------ 114
PRCPD + V +S
Sbjct: 479 PRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPND 538
Query: 115 ---CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP 171
C + G Y G F + C C C GNV C + C L C PV +P
Sbjct: 539 CSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLP 591
Query: 172 DSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP--PSRQA----GGLS-- 223
CC C +P A H+ H+ ++ PP P R+ G +S
Sbjct: 592 GECCPQCPAPAGCP----------RPG---AAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 638
Query: 224 -----RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLR 278
P A +G S C+ GK ++ GE +
Sbjct: 639 RLPCPPAPCAHPRQGPCCPSCDG------------------CLYQGKEFASGERFPSPTA 680
Query: 279 AFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 324
A C LC C C+ C C +P + G CC C G
Sbjct: 681 A-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDCDG 718
Score = 68.6 bits (166), Expect = 1e-11
Identities = 74/299 (24%), Positives = 107/299 (35%), Gaps = 64/299 (21%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C+ +++ G RW P C +C+C E G V C+R++C + C P PH CC
Sbjct: 896 CLAHGEEHPEGSRWVPPDSA-----CSSCVCHE-GVVTCARIQCIS-SCAQPRQGPHDCC 948
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQP--NQCTQCSCS---EG- 150
P+C D CE+ G Y+ GE F QP + C C C EG
Sbjct: 949 PQCSD-------------CEHEGRKYEPGESF---------QPGADPCEVCICEPQPEGP 986
Query: 151 -NVYCGLKTCPKLTCAFPVSV----PDSCCRVCRGDGELSWEHSDGDIFRQPANREARHS 205
++ C + CP L P + P CC C E S+G + + A + ++
Sbjct: 987 PSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC---AEALSNCSEGLLGSELAPPDPCYT 1043
Query: 206 YHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGK 265
QA P L + G+ + Q CV G+
Sbjct: 1044 CQCQDLTWLCIHQACPELSCP--------LSERHTPPGSCCPVC----RAPTQSCVHQGR 1091
Query: 266 TYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKIDGKCCKVC 322
+ GE W + C C+C C+ C + P K P G CC C
Sbjct: 1092 EVASGERW-------TVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/163 (26%), Positives = 66/163 (40%), Gaps = 27/163 (16%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C+ Q ++++ GE + P G C C C + G V C R++CP + C V CC
Sbjct: 837 CLSQGREHQDGEEFEG---PAGS--CEWCRC-QAGQVSCVRLQCPPLPCKLQVTERGSCC 890
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
PRC + C +G + G +V + C+ C C EG V C
Sbjct: 891 PRC-------------RGCLAHGEEHPEGSRWVPPD-------SACSSCVCHEGVVTCAR 930
Query: 157 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPAN 199
C +CA P P CC C ++ G+ F+ A+
Sbjct: 931 IQCIS-SCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGAD 972
Score = 39.7 bits (91), Expect = 0.006
Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 8/88 (9%)
Query: 256 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 315
H + C NG+TY +GE++ P+ C C C +C+ C + C
Sbjct: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLTGAVQCQGPSC-SELNCLESCTPP 185
Query: 316 GKCCKVCPGKKAKEELPGQSFDNKGYFC 343
G+CC +C + GQ + G C
Sbjct: 186 GECCPICCTEGGSHWEHGQEWTTPGDPC 213
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 95.1 bits (235), Expect = 1e-19
Identities = 74/292 (25%), Positives = 115/292 (39%), Gaps = 42/292 (14%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C ++ Y +W EP L C + +E+G VRC VHC +P+ +CC
Sbjct: 108 CTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESG------VRCV-VHCKNPLEHLGMCC 160
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P CP C + G YQ GE F EG ++CT+CSC+ G C
Sbjct: 161 PTCP-------------GCVFEGVQYQEGEEFQPEG-------SKCTKCSCTGGRTQCVR 200
Query: 157 KTCPKLTCAFPVS--VPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 214
+ CP L+C +S P CC C G ++ +FR + S+ +
Sbjct: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDV-YDNGSSFLYDNCTAC 259
Query: 215 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWH 274
R + + + SH G Q+ G + ++ + +VC K + GE W
Sbjct: 260 TCRDSTVVCK--RKCSHPGGCDQGQE--GCCEECLLRVPPEDIKVCKFGNKIFQDGEMW- 314
Query: 275 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGK-CCKVCPGK 325
+ C +C C + EC+ C C + ++ K CC +C K
Sbjct: 315 ------SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360
Score = 50.1 bits (118), Expect = 4e-06
Identities = 64/289 (22%), Positives = 99/289 (34%), Gaps = 48/289 (16%)
Query: 62 CVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNG 119
C+ C+C N V C R +CP + C + CC +C K C Y G
Sbjct: 67 CIMCVCL-NKEVTCKREKCPVLSRDCALAIKQRGACCEQC-------------KGCTYEG 112
Query: 120 TTYQHGELFVAEGLFQNRQPNQ-CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 178
TY F+ + P + C C EG V C + C P+ CC C
Sbjct: 113 NTYNSS--------FKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTC 163
Query: 179 RGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSH--RGALM 236
G ++ +G+ F+ ++ + S R+ + P SH G
Sbjct: 164 PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV--REVCPILSCPQHLSHIPPGQCC 221
Query: 237 DSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE 296
+ + + C+ Y +G S F C CTC +
Sbjct: 222 PKCLGQRKVFDLPFGS-------CLFRSDVYDNGSS-------FLYDNCTACTCRDSTVV 267
Query: 297 CKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGE 345
CK+ C + C Q+ CC+ C + E++ F NK + GE
Sbjct: 268 CKR-KCSHPGGCDQGQE---GCCEECLLRVPPEDIKVCKFGNKIFQDGE 312
Score = 47.8 bits (112), Expect = 2e-05
Identities = 47/206 (22%), Positives = 73/206 (35%), Gaps = 49/206 (23%)
Query: 140 NQCTQCSCSEGNVYCGLKTCPKLT--CAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQP 197
N C C C V C + CP L+ CA + +CC C+G ++ ++ P
Sbjct: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSP 124
Query: 198 ANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHG 257
A +P RQ G + +S G + N +H
Sbjct: 125 A-------------EPCVLRQC-----------QEGVVTES----GVRCVVHCKNPLEHL 156
Query: 258 QVC-------VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKY 310
+C V G Y GE + P +C C+C + +C + CP
Sbjct: 157 GMCCPTCPGCVFEGVQYQEGEEFQPEGS-----KCTKCSCTGGRTQCVREVCP---ILSC 208
Query: 311 PQKID----GKCCKVCPGKKAKEELP 332
PQ + G+CC C G++ +LP
Sbjct: 209 PQHLSHIPPGQCCPKCLGQRKVFDLP 234
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 94.7 bits (234), Expect = 2e-19
Identities = 80/293 (27%), Positives = 114/293 (38%), Gaps = 39/293 (13%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKS-CEYNGT 120
C C C NG +C+ + CP C +P P CCP C D ++++ S C G
Sbjct: 626 CRECYCL-NGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPG- 683
Query: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC-- 178
GE FV EG N + CTQC+C G V C + CP L C P DSCC C
Sbjct: 684 ----GEYFV-EGETWNI--DSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTD 736
Query: 179 --------RGDGELSW-EHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGAR 229
R + ++ ++ +GDIF + + D S + P
Sbjct: 737 QPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFS---ESCPSVS 793
Query: 230 SHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCT 289
R L G I + VC +GK Y+ E W + C C
Sbjct: 794 CERPVL-----RKGQCCPYCIEDTIPKKVVCHFSGKAYADEERW-------DLDSCTHCY 841
Query: 290 CNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE--ELPGQSFDNKG 340
C + C + CP PC P ++G CC +CP E +P + +++G
Sbjct: 842 CLQGQTLCSTVSCP-PLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRG 893
Score = 73.9 bits (180), Expect = 3e-13
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 55 EPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKS 114
E + + C C C +G VLC CP + C +P CCP+C D P ++ +
Sbjct: 691 ETWNIDSCTQCTC-HSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQ--PFRPSLSRNN 747
Query: 115 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSC 174
N G++F+A ++ +P+ CT C C + + C ++CP ++C PV C
Sbjct: 748 SVPNYCKNDEGDIFLAA---ESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQC 804
Query: 175 CRVCRGD 181
C C D
Sbjct: 805 CPYCIED 811
Score = 72.8 bits (177), Expect = 6e-13
Identities = 41/135 (30%), Positives = 58/135 (42%), Gaps = 22/135 (16%)
Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSL 103
+ E W P + C +CIC ++ + C CP+V C PV CCP C +
Sbjct: 761 FLAAESWKPDV-------CTSCICIDSV-ISCFSESCPSVSCERPVLRKGQCCPYCIEDT 812
Query: 104 PPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLT 163
P KV C ++G Y E + + CT C C +G C +CP L
Sbjct: 813 IP--KKVV---CHFSGKAYADEERWDLDS---------CTHCYCLQGQTLCSTVSCPPLP 858
Query: 164 CAFPVSVPDSCCRVC 178
C P++V SCC +C
Sbjct: 859 CVEPINVEGSCCPMC 873
Score = 69.7 bits (169), Expect = 5e-12
Identities = 44/152 (28%), Positives = 66/152 (43%), Gaps = 23/152 (15%)
Query: 28 EQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS 87
E V ++ C+F + +Y G+ + + C C C + G +C +C ++C
Sbjct: 327 ECVNDTKPACVFNNVEYYDGDMFR-------MDNCRFCRC-QGGVAICFTAQCGEINC-E 377
Query: 88 PVHIPH-LCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCS 146
++P CCP C D + P NN C NG HG+ + + + CT C
Sbjct: 378 RYYVPEGECCPVCEDPVYPFNNPA---GCYANGLILAHGDRW---------REDDCTFCQ 425
Query: 147 CSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 178
C G +C C + TC PV VP CC VC
Sbjct: 426 CVNGERHCVATVCGQ-TCTNPVKVPGECCPVC 456
Score = 58.2 bits (139), Expect = 2e-08
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C F K Y ERW L C +C C + G LCS V CP + C+ P+++ CC
Sbjct: 819 CHFSGKAYADEERWD-------LDSCTHCYCLQ-GQTLCSTVSCPPLPCVEPINVEGSCC 870
Query: 97 PRCPDSLPPVNNKVTSKSCEYNG 119
P CP+ P + + + G
Sbjct: 871 PMCPEMYVPEPTNIPIEKTNHRG 893
Score = 42.7 bits (99), Expect = 7e-04
Identities = 61/274 (22%), Positives = 84/274 (30%), Gaps = 45/274 (16%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSL-----PPV-----NNKVT 111
C C C NG C C C +PV +P CCP C + PP N +T
Sbjct: 421 CTFCQCV-NGERHCVATVCGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLT 478
Query: 112 SKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG-LKTCPKLTCAFPVSV 170
K C NG H N C C C C K L C F
Sbjct: 479 GKDC-INGFKRDH---------------NGCRTCQCINTEELCSERKQGCTLNCPFGFLT 522
Query: 171 PDSCCRVCR-GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGAR 229
C +C D + + +H P + +
Sbjct: 523 DAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQ 582
Query: 230 SHRGALM-DSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLC 288
G L+ ++AS + +++ G +G + + ESWH C C
Sbjct: 583 DSHGCLICKCREASASAGPPILS-----GTCLTVDGHHHKNEESWHDG--------CREC 629
Query: 289 TCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
C ++ C I CP C P G+CC C
Sbjct: 630 YCLNGREMCALITCPVP-ACGNPTIHPGQCCPSC 662
Score = 42.7 bits (99), Expect = 7e-04
Identities = 31/129 (24%), Positives = 49/129 (37%), Gaps = 18/129 (13%)
Query: 61 YC-VNCICSENGNVLCSRVRCPNVHC--LSPVHIPH-----LCCPRCPDSLPPVNNKVTS 112
YC + + +++G +C +CP + C + P+ L C +C ++ + S
Sbjct: 547 YCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLIC-KCREASASAGPPILS 605
Query: 113 KSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPD 172
+C + E +G C +C C G C L TCP C P P
Sbjct: 606 GTCLTVDGHHHKNEESWHDG---------CRECYCLNGREMCALITCPVPACGNPTIHPG 656
Query: 173 SCCRVCRGD 181
CC C D
Sbjct: 657 QCCPSCADD 665
Score = 42.4 bits (98), Expect = 9e-04
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 9/63 (14%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319
C +NG +HG+ W + +C C C ++ C C C P K+ G+CC
Sbjct: 403 CYANGLILAHGDRWRED-------DCTFCQCVNGERHCVATVCGQT--CTNPVKVPGECC 453
Query: 320 KVC 322
VC
Sbjct: 454 PVC 456
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 77.0 bits (188), Expect = 3e-14
Identities = 54/195 (27%), Positives = 79/195 (40%), Gaps = 41/195 (21%)
Query: 2 RKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDK--KYRVGERWHPYLEPYGL 59
R++W++G + F T Q T C D ++ +G+ W P +P
Sbjct: 545 REEWRLGPGQCCF------------TCQEPTPSTGCSLDDNGVEFPIGQIWSPG-DP--- 588
Query: 60 VYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNG 119
C CIC +G+V C R C + C P+ IP CCP C S C Y G
Sbjct: 589 --CELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDC------------SAGCTYTG 633
Query: 120 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
+ + E F + + C C C G+V C CP +TC +P CC VCR
Sbjct: 634 RIFYNNETFPSV-------LDPCLSCICLLGSVACSPVDCP-ITCTYPFHPDGECCPVCR 685
Query: 180 GDGELSWEHSDGDIF 194
+ ++G +F
Sbjct: 686 DCNYEGRKVANGQVF 700
Score = 70.1 bits (170), Expect = 4e-12
Identities = 43/142 (30%), Positives = 60/142 (42%), Gaps = 28/142 (19%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + + E + L+P C++CIC G+V CS V CP + C P H CC
Sbjct: 629 CTYTGRIFYNNETFPSVLDP-----CLSCICLL-GSVACSPVDCP-ITCTYPFHPDGECC 681
Query: 97 PRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 156
P C D C Y G +G++F + CT+C+C G V C
Sbjct: 682 PVCRD-------------CNYEGRKVANGQVFTLDD-------EPCTRCTCQLGEVSCEK 721
Query: 157 KTCPKLTCAFPVSVPDSCCRVC 178
C + CA P +P CC C
Sbjct: 722 VPCQR-ACADPALLPGDCCSSC 742
Score = 61.6 bits (148), Expect = 1e-09
Identities = 65/267 (24%), Positives = 96/267 (35%), Gaps = 49/267 (18%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHI--PHLCCPRCPDSLPPVNNKVTSKSCEYNG 119
C C+C +NG V CS + CP + C P CC C + P T S + NG
Sbjct: 521 CTTCVC-QNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPTPS-----TGCSLDDNG 574
Query: 120 TTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 178
+ G+++ + C C C ++G+V C C +C P+ +P CC C
Sbjct: 575 VEFPIGQIW--------SPGDPCELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDC 625
Query: 179 RGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDS 238
+ G IF Y+ + PS LS L+ S
Sbjct: 626 SAGCTYT-----GRIF-----------YNNETF---PSVLDPCLSCI--------CLLGS 658
Query: 239 QQASGTIVQIVINNK-HKHGQVC-VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE 296
S I H G+ C V Y + + + C CTC + +
Sbjct: 659 VACSPVDCPITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVS 718
Query: 297 CKKIHCPNRYPCKYPQKIDGKCCKVCP 323
C+K+ C + C P + G CC CP
Sbjct: 719 CEKVPC--QRACADPALLPGDCCSSCP 743
Score = 58.9 bits (141), Expect = 9e-09
Identities = 65/270 (24%), Positives = 90/270 (33%), Gaps = 57/270 (21%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL---CCPRCPDSLPPVNNKVTSKSCEYN 118
C C C E+G V C +VRC C P IP CCP C C ++
Sbjct: 404 CSQCWC-EDGKVTCEKVRC-EAACSHP--IPSRDGGCCPSCT-------------GCFHS 446
Query: 119 GTTYQHGELFVAEGLFQNRQPNQ-CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRV 177
G G++F PN+ CT C C GNV C CP C P C
Sbjct: 447 GVVRAEGDVF--------SPPNENCTVCVCLAGNVSCISPECPSGPCQTPPQTDCCTCVP 498
Query: 178 CRGDGELSWEHSDGDIFRQPANR----EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG 233
R W ++DG +F + ++ + P P G
Sbjct: 499 VRCYFHGRW-YADGAVFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCF 557
Query: 234 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVT 293
+ ++G + NG + G+ W P C LC C
Sbjct: 558 TCQEPTPSTGCSLD--------------DNGVEFPIGQIWSPG------DPCELCICQAD 597
Query: 294 -KQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
CK+ C + C +P +I G+CC C
Sbjct: 598 GSVSCKRTDCVD--SCPHPIRIPGQCCPDC 625
Score = 45.4 bits (106), Expect = 1e-04
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 7/73 (9%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C ++ +K G+ + EP C C C + G V C +V C C P +P CC
Sbjct: 687 CNYEGRKVANGQVFTLDDEP-----CTRCTC-QLGEVSCEKVPCQRA-CADPALLPGDCC 739
Query: 97 PRCPDSLPPVNNK 109
CPDSL P+ K
Sbjct: 740 SSCPDSLSPLEEK 752
Score = 42.7 bits (99), Expect = 7e-04
Identities = 50/203 (24%), Positives = 72/203 (35%), Gaps = 36/203 (17%)
Query: 142 CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS-CCRVCRGDGELSWEHSDGDIFRQPANR 200
C+QC C +G V C C + C+ P+ D CC C G ++GD+F P N
Sbjct: 404 CSQCWCEDGKVTCEKVRC-EAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVF-SPPNE 461
Query: 201 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 260
AG +S Q T V + C
Sbjct: 462 NCTVCVCL----------AGNVSCISPECPSGPCQTPPQTDCCTCVPVR----------C 501
Query: 261 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPN-RYPCKYPQKIDGKCC 319
+G+ Y+ G + + G EC C C + EC + CP P + + G+CC
Sbjct: 502 YFHGRWYADGAVF-----SGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCC 556
Query: 320 KVCPGKKAKEELP--GQSFDNKG 340
C +E P G S D+ G
Sbjct: 557 FTC-----QEPTPSTGCSLDDNG 574
>gi|38348414 von Willebrand factor C domain containing 2 [Homo
sapiens]
Length = 325
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/138 (33%), Positives = 65/138 (47%), Gaps = 28/138 (20%)
Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIP-HLCCPRCPDS 102
Y +GE++ P G C C+C+E G LC++ CP +H +H+ CCP+C
Sbjct: 163 YAIGEKFAP-----GPSACP-CLCTEEGP-LCAQPECPRLHPRC-IHVDTSQCCPQC--- 211
Query: 103 LPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCPK 161
K CE+ G TYQ E FV + C +C C + G V C + CP+
Sbjct: 212 ------KERKNYCEFRGKTYQTLEEFVV---------SPCERCRCEANGEVLCTVSACPQ 256
Query: 162 LTCAFPVSVPDSCCRVCR 179
C PV PD CC +C+
Sbjct: 257 TECVDPVYEPDQCCPICK 274
Score = 66.2 bits (160), Expect = 6e-11
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 22/129 (17%)
Query: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P
Sbjct: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
Query: 89 VHIPHLCCPRCPD--------SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPN 140
V+ P CCP C + ++ P +V + C TY+ EG ++ +
Sbjct: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-------EGTWRIERQA 315
Query: 141 QCTQCSCSE 149
CT+ C +
Sbjct: 316 MCTRHECRQ 324
>gi|30089980 chordin [Homo sapiens]
Length = 955
Score = 73.9 bits (180), Expect = 3e-13
Identities = 56/213 (26%), Positives = 75/213 (35%), Gaps = 68/213 (31%)
Query: 114 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS 173
+C + G HG + N P C+ C+C V C CP +C PV PD
Sbjct: 704 TCFFEGQQRPHGARWAP-----NYDP-LCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQ 757
Query: 174 CCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG 233
CC VC P ++ R P SR G F G RS R
Sbjct: 758 CCPVC------------------PEKQDVRDLPGL-----PRSRDPGEGCYFDGDRSWRA 794
Query: 234 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--N 291
A G WHP + FG+++C +CTC
Sbjct: 795 A-----------------------------------GTRWHPVVPPFGLIKCAVCTCKGG 819
Query: 292 VTKQECKKIHCPNRYPCKYPQKID-GKCCKVCP 323
+ C+K+ CP R C P +++ CCK CP
Sbjct: 820 TGEVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
Score = 73.2 bits (178), Expect = 5e-13
Identities = 46/151 (30%), Positives = 64/151 (42%), Gaps = 14/151 (9%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C F+ ++ G RW P +P C C C V+C V CP C PV P CC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759
Query: 97 PRCPD-----SLPPV-NNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC--S 148
P CP+ LP + ++ + C ++G + +C C+C
Sbjct: 760 PVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGG 819
Query: 149 EGNVYCGLKTCPKLTCAFPVSV-PDSCCRVC 178
G V+C CP+L CA PV V P CC+ C
Sbjct: 820 TGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
Score = 60.1 bits (144), Expect = 4e-09
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 14/84 (16%)
Query: 260 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 306
C GK Y+ E+WHP+L FG++ CVLC C + CK I CP
Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109
Query: 307 PCKYPQKIDGKCCKVCPGKKAKEE 330
C P+++ G CC+ CP +++ E
Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSE 133
Score = 57.0 bits (136), Expect = 3e-08
Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 12/93 (12%)
Query: 37 CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84
C F K Y + E WHP L EP+G++ CV C C G V C ++ CP
Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
Query: 85 CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEY 117
C P +P CC CP + + S EY
Sbjct: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEY 143
Score = 52.4 bits (124), Expect = 9e-07
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319
C G+ HG W PN C LCTC C + CP C +P + +CC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759
Query: 320 KVCPGKKAKEELPG 333
VCP K+ +LPG
Sbjct: 760 PVCPEKQDVRDLPG 773
Score = 36.2 bits (82), Expect = 0.064
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 4/81 (4%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95
C F + + + WHP + P+G + C+ C C G C R C + C S C
Sbjct: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928
Query: 96 CPRCPDSLPPVNNKVTSKSCE 116
C RC P T E
Sbjct: 929 CSRCTAHRRPAPETRTDPELE 949
Score = 34.7 bits (78), Expect = 0.18
Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 15/119 (12%)
Query: 115 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE----------GNVYC-GLKT-CPKL 162
C + G Y E + + L + +C C+C G V C +K CP
Sbjct: 51 CTFGGKVYALDETWHPD-LGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
Query: 163 TCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 221
C P +P CC+ C + S G F P R+ H + +P +A G
Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 71.2 bits (173), Expect = 2e-12
Identities = 71/299 (23%), Positives = 103/299 (34%), Gaps = 54/299 (18%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP---VHIPH 93
C ++ ++ GE W L C C+C NG C +C + C V +P
Sbjct: 159 CSYEGHVFQDGEDWR-------LSRCAKCLC-RNGVAQCFTAQCQPLFCNQDETVVRVPG 210
Query: 94 LCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVY 153
CCP+C +++SC G Y+HGE + N CT C C G V
Sbjct: 211 KCCPQC-----------SARSCSAAGQVYEHGEQW---------SENACTTCICDRGEVR 250
Query: 154 CGLKTCPKLTCAFPVSVP---DSCCRVCRGD-GELSWEHSDGDIFRQPANREARHSYHRS 209
C + C L C S CC C G S+ DG + Q +
Sbjct: 251 CHKQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSY---DGVVRYQDEMWKGSACEFCM 307
Query: 210 HYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNG---KT 266
+ Q G ++ AR +D + I + + G+ SN K
Sbjct: 308 CDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKR 367
Query: 267 YSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPC---KYPQKIDGKCCKVC 322
GE W C +C C + C + CP PC ++ G+CC C
Sbjct: 368 IPEGEKWEDG-------PCKVCECRGAQVTCYEPSCP---PCPVGTLALEVKGQCCPDC 416
Score = 69.7 bits (169), Expect = 5e-12
Identities = 77/312 (24%), Positives = 111/312 (35%), Gaps = 77/312 (24%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH- 90
HSE C++QD W P C +C C V+C C N C
Sbjct: 23 HSEGACVYQDSLLADATIWKPDS-------CQSCRC-HGDIVICKPAVCRNPQCAFEKGE 74
Query: 91 ----IPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCS 146
+ CCP C P SC + ++HG + + + C+ CS
Sbjct: 75 VLQIAANQCCPECVLRTPG--------SCHHEKKIHEHGTEWAS---------SPCSVCS 117
Query: 147 CSEGNVYCGLKTCPKLTCAFP--VSVPD-SCCRVCRGDGE-LSWE---HSDGDIFR---- 195
C+ G V C + CP L+C +P+ SCC VC G G+ S+E DG+ +R
Sbjct: 118 CNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRC 177
Query: 196 -QPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKH 254
+ R + P Q + R PG + +
Sbjct: 178 AKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCS-------------------- 217
Query: 255 KHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHC-PNRYPCKYPQ- 312
+ C + G+ Y HGE W N C C C+ + C K C P R C Q
Sbjct: 218 --ARSCSAAGQVYEHGEQWSEN-------ACTTCICDRGEVRCHKQACLPLR--CGKGQS 266
Query: 313 --KIDGKCCKVC 322
+ G+CC+ C
Sbjct: 267 RARRHGQCCEEC 278
Score = 34.3 bits (77), Expect = 0.24
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 15/70 (21%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV-----TKQECKKIHCPNRYPCKYPQKI 314
C K + HG W + C +C+CN T Q C + C ++ P
Sbjct: 95 CHHEKKIHEHGTEWASS-------PCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIP--- 144
Query: 315 DGKCCKVCPG 324
+G CC VC G
Sbjct: 145 EGSCCPVCVG 154
>gi|122937446 von Willebrand factor C domain-containing protein
2-like [Homo sapiens]
Length = 222
Score = 68.6 bits (166), Expect = 1e-11
Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 30/139 (21%)
Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPD 101
Y++GER+ P G C C+C+ +G V C + CP +H C H + CCP C
Sbjct: 61 YKLGERFFP-----GHSNCP-CVCALDGPV-CDQPECPKIHPKCTKVEH--NGCCPEC-- 109
Query: 102 SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN-VYCGLKTCP 160
K CEY+G Y+ E F +P+ C C C N V+C + C
Sbjct: 110 -------KEVKNFCEYHGKNYKILEEF---------KPSPCEWCRCEPSNEVHCVVADCA 153
Query: 161 KLTCAFPVSVPDSCCRVCR 179
C PV P+ CC VC+
Sbjct: 154 VPECVNPVYEPEQCCPVCK 172
Score = 45.4 bits (106), Expect = 1e-04
Identities = 32/139 (23%), Positives = 50/139 (35%), Gaps = 30/139 (21%)
Query: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84
G + K + +C + K Y++ E + P P C C C + V C C
Sbjct: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156
Query: 85 CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ 144
C++PV+ P CCP C NG G + G+ + ++C
Sbjct: 157 CVNPVYEPEQCCPVCK-----------------NGPNCFAGTTIIPAGI--EVKVDECNI 197
Query: 145 CSCSEGN----VYCGLKTC 159
C C G+ C + C
Sbjct: 198 CHCHNGDWWKPAQCSKREC 216
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 60.5 bits (145), Expect = 3e-09
Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNG-T 120
C C C + G + C R C C +P CCP C + +VTS+ + NG
Sbjct: 607 CSVCSCKD-GKIFCRRTACD---CQNP-SADLFCCPEC-------DTRVTSQCLDQNGHK 654
Query: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y+ G+ + + C QC C EG V C TCP L+C + + CC C
Sbjct: 655 LYRSGDNWT----------HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVS 704
Query: 181 D 181
D
Sbjct: 705 D 705
Score = 57.8 bits (138), Expect = 2e-08
Identities = 50/186 (26%), Positives = 71/186 (38%), Gaps = 42/186 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88
H E C YR + W +C NC C ++G V C R+ CP ++C P
Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCS 148
VHI CC KV C Y G G+ + + C +C
Sbjct: 321 VHIAGQCC------------KVCRPKCIYGGKVLAEGQRILTKS---------CREC--- 356
Query: 149 EGNVYCGL-KTCPKLTCAFPVSV--PDSCCRVCRG-----DGELSWEHSDGDIFRQPANR 200
G V + + CP L C+ + + CCRVCRG +G E+S+ + A
Sbjct: 357 RGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATC 416
Query: 201 EARHSY 206
E + Y
Sbjct: 417 ECKSGY 422
Score = 49.7 bits (117), Expect = 6e-06
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 23/126 (18%)
Query: 37 CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ K YR G+ W C C C E G V C + CPN+ C +
Sbjct: 647 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 697
Query: 95 CCPRCPDSLPPVNNKVT---SKSC-EYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEG 150
CCPRC P + + +T K+C + G + G ++ G + CT C C G
Sbjct: 698 CCPRCVSD-PCLADNITYDIRKTCLDSYGVSRLSGSVWTMAG-------SPCTTCKCKNG 749
Query: 151 NVYCGL 156
V C +
Sbjct: 750 RVCCSV 755
Score = 48.9 bits (115), Expect = 9e-06
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 103 LPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKL 162
L + N K+C+ +G Y+ + +V + C C+C G V C +CP L
Sbjct: 261 LSQLENCHCEKTCQVSGLLYRDQDSWV--------DGDHCRNCTCKSGAVECRRMSCPPL 312
Query: 163 TC---AFPVSVPDSCCRVCR 179
C + PV + CC+VCR
Sbjct: 313 NCSPDSLPVHIAGQCCKVCR 332
Score = 43.1 bits (100), Expect = 5e-04
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 315
+ C +G Y +SW C CTC EC+++ CP N P P I
Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324
Query: 316 GKCCKVCPGK 325
G+CCKVC K
Sbjct: 325 GQCCKVCRPK 334
Score = 36.2 bits (82), Expect = 0.064
Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 265 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
K Y G++W + C C C + +C + CPN C+Y ++G+CC C
Sbjct: 654 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 702
Score = 31.2 bits (69), Expect = 2.0
Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Query: 112 SKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP 171
S C + G +G+++ + ++C+ CSC +G ++C C C P S
Sbjct: 584 SGDCPHEGGLKHNGQVWTLK-------EDRCSVCSCKDGKIFCRRTAC---DCQNP-SAD 632
Query: 172 DSCCRVC 178
CC C
Sbjct: 633 LFCCPEC 639
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 60.5 bits (145), Expect = 3e-09
Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNG-T 120
C C C + G + C R C C +P CCP C + +VTS+ + NG
Sbjct: 654 CSVCSCKD-GKIFCRRTACD---CQNP-SADLFCCPEC-------DTRVTSQCLDQNGHK 701
Query: 121 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y+ G+ + + C QC C EG V C TCP L+C + + CC C
Sbjct: 702 LYRSGDNWT----------HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVS 751
Query: 181 D 181
D
Sbjct: 752 D 752
Score = 57.8 bits (138), Expect = 2e-08
Identities = 50/186 (26%), Positives = 71/186 (38%), Gaps = 42/186 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88
H E C YR + W +C NC C ++G V C R+ CP ++C P
Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCS 148
VHI CC KV C Y G G+ + + C +C
Sbjct: 321 VHIAGQCC------------KVCRPKCIYGGKVLAEGQRILTKS---------CREC--- 356
Query: 149 EGNVYCGL-KTCPKLTCAFPVSV--PDSCCRVCRG-----DGELSWEHSDGDIFRQPANR 200
G V + + CP L C+ + + CCRVCRG +G E+S+ + A
Sbjct: 357 RGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATC 416
Query: 201 EARHSY 206
E + Y
Sbjct: 417 ECKSGY 422
Score = 49.7 bits (117), Expect = 6e-06
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 23/126 (18%)
Query: 37 CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ K YR G+ W C C C E G V C + CPN+ C +
Sbjct: 694 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 744
Query: 95 CCPRCPDSLPPVNNKVT---SKSC-EYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEG 150
CCPRC P + + +T K+C + G + G ++ G + CT C C G
Sbjct: 745 CCPRCVSD-PCLADNITYDIRKTCLDSYGVSRLSGSVWTMAG-------SPCTTCKCKNG 796
Query: 151 NVYCGL 156
V C +
Sbjct: 797 RVCCSV 802
Score = 48.9 bits (115), Expect = 9e-06
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 103 LPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKL 162
L + N K+C+ +G Y+ + +V + C C+C G V C +CP L
Sbjct: 261 LSQLENCHCEKTCQVSGLLYRDQDSWV--------DGDHCRNCTCKSGAVECRRMSCPPL 312
Query: 163 TC---AFPVSVPDSCCRVCR 179
C + PV + CC+VCR
Sbjct: 313 NCSPDSLPVHIAGQCCKVCR 332
Score = 43.1 bits (100), Expect = 5e-04
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 315
+ C +G Y +SW C CTC EC+++ CP N P P I
Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324
Query: 316 GKCCKVCPGK 325
G+CCKVC K
Sbjct: 325 GQCCKVCRPK 334
Score = 36.2 bits (82), Expect = 0.064
Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 265 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 322
K Y G++W + C C C + +C + CPN C+Y ++G+CC C
Sbjct: 701 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 749
Score = 31.2 bits (69), Expect = 2.0
Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Query: 112 SKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP 171
S C + G +G+++ + ++C+ CSC +G ++C C C P S
Sbjct: 631 SGDCPHEGGLKHNGQVWTLK-------EDRCSVCSCKDGKIFCRRTAC---DCQNP-SAD 679
Query: 172 DSCCRVC 178
CC C
Sbjct: 680 LFCCPEC 686
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG T
Sbjct: 683 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC-------DPRLSSQCLHQNGET 730
Query: 122 -YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 731 LYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVT 780
Query: 181 D 181
D
Sbjct: 781 D 781
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 38/167 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 292 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 342
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQC 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 343 AYVDGKCCKEC------------KSICQFQGRTYFEGERNTVYSSSGV--------CVLY 382
Query: 146 SCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 189
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 383 ECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 429
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 21/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 723 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 773
Query: 95 CCPRC---PDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 151
CCPRC P + N +T + G ++ G +CT C C G+
Sbjct: 774 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 826
Query: 152 VYCGL 156
+ C +
Sbjct: 827 ICCSV 831
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 315
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 295 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 346
Query: 316 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 353
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 347 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 394
Score = 34.7 bits (78), Expect = 0.18
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 21/97 (21%)
Query: 98 RCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLK 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 652 RCP------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRRM 698
Query: 158 TCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 192
C C P +V CC C D LS + H +G+
Sbjct: 699 VC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 729
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 19/155 (12%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 351 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 407
Query: 89 VHIPHLCCPRCP--DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 144
+ + H CC C D +N + + C +G R+ N +
Sbjct: 408 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 464
Query: 145 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
C+EG YC T V+ P S +C+
Sbjct: 465 DECAEGRHYCRENT-------MCVNTPGSFMCICK 492
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 259 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 312
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 356 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 409
Query: 313 KIDGKCCKVCPG 324
+ CCKVC G
Sbjct: 410 -LSHSCCKVCKG 420
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG T
Sbjct: 659 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC-------DPRLSSQCLHQNGET 706
Query: 122 -YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 707 LYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVT 756
Query: 181 D 181
D
Sbjct: 757 D 757
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 38/167 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 268 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 318
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQC 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 319 AYVDGKCCKEC------------KSICQFQGRTYFEGERNTVYSSSGV--------CVLY 358
Query: 146 SCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 189
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 359 ECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 405
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 21/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 699 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 749
Query: 95 CCPRC---PDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 151
CCPRC P + N +T + G ++ G +CT C C G+
Sbjct: 750 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 802
Query: 152 VYCGL 156
+ C +
Sbjct: 803 ICCSV 807
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 315
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 271 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 322
Query: 316 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 353
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 323 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 370
Score = 34.7 bits (78), Expect = 0.18
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 21/97 (21%)
Query: 98 RCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLK 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 628 RCP------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRRM 674
Query: 158 TCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 192
C C P +V CC C D LS + H +G+
Sbjct: 675 VC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 705
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 19/155 (12%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 327 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 383
Query: 89 VHIPHLCCPRCP--DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 144
+ + H CC C D +N + + C +G R+ N +
Sbjct: 384 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 440
Query: 145 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
C+EG YC T V+ P S +C+
Sbjct: 441 DECAEGRHYCRENT-------MCVNTPGSFMCICK 468
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 259 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 312
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 332 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 385
Query: 313 KIDGKCCKVCPG 324
+ CCKVC G
Sbjct: 386 -LSHSCCKVCKG 396
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG T
Sbjct: 660 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC-------DPRLSSQCLHQNGET 707
Query: 122 -YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 708 LYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVT 757
Query: 181 D 181
D
Sbjct: 758 D 758
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 38/167 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQC 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 320 AYVDGKCCKEC------------KSICQFQGRTYFEGERNTVYSSSGV--------CVLY 359
Query: 146 SCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 189
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 360 ECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 406
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 21/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750
Query: 95 CCPRC---PDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 151
CCPRC P + N +T + G ++ G +CT C C G+
Sbjct: 751 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 803
Query: 152 VYCGL 156
+ C +
Sbjct: 804 ICCSV 808
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 315
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323
Query: 316 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 353
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 324 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371
Score = 34.7 bits (78), Expect = 0.18
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 21/97 (21%)
Query: 98 RCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLK 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 629 RCP------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRRM 675
Query: 158 TCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 192
C C P +V CC C D LS + H +G+
Sbjct: 676 VC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 706
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 19/155 (12%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384
Query: 89 VHIPHLCCPRCP--DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 144
+ + H CC C D +N + + C +G R+ N +
Sbjct: 385 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 441
Query: 145 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
C+EG YC T V+ P S +C+
Sbjct: 442 DECAEGRHYCRENT-------MCVNTPGSFMCICK 469
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 259 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 312
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386
Query: 313 KIDGKCCKVCPG 324
+ CCKVC G
Sbjct: 387 -LSHSCCKVCKG 397
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG T
Sbjct: 710 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC-------DPRLSSQCLHQNGET 757
Query: 122 -YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 758 LYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVT 807
Query: 181 D 181
D
Sbjct: 808 D 808
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 38/167 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 319 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 369
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQC 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 370 AYVDGKCCKEC------------KSICQFQGRTYFEGERNTVYSSSGV--------CVLY 409
Query: 146 SCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 189
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 410 ECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 456
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 21/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 750 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 800
Query: 95 CCPRC---PDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 151
CCPRC P + N +T + G ++ G +CT C C G+
Sbjct: 801 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 853
Query: 152 VYCGL 156
+ C +
Sbjct: 854 ICCSV 858
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 315
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 322 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 373
Query: 316 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 353
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 374 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 421
Score = 34.7 bits (78), Expect = 0.18
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 21/97 (21%)
Query: 98 RCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLK 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 679 RCP------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRRM 725
Query: 158 TCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 192
C C P +V CC C D LS + H +G+
Sbjct: 726 VC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 756
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 19/155 (12%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 378 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 434
Query: 89 VHIPHLCCPRCP--DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 144
+ + H CC C D +N + + C +G R+ N +
Sbjct: 435 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 491
Query: 145 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
C+EG YC T V+ P S +C+
Sbjct: 492 DECAEGRHYCRENT-------MCVNTPGSFMCICK 519
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 259 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 312
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 383 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 436
Query: 313 KIDGKCCKVCPG 324
+ CCKVC G
Sbjct: 437 -LSHSCCKVCKG 447
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 58.9 bits (141), Expect = 9e-09
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG T
Sbjct: 660 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC-------DPRLSSQCLHQNGET 707
Query: 122 -YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRG 180
Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 708 LYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVT 757
Query: 181 D 181
D
Sbjct: 758 D 758
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 38/167 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319
Query: 89 VHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQC 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 320 AYVDGKCCKEC------------KSICQFQGRTYFEGERNTVYSSSGV--------CVLY 359
Query: 146 SCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 189
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 360 ECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 406
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 21/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750
Query: 95 CCPRC---PDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 151
CCPRC P + N +T + G ++ G +CT C C G+
Sbjct: 751 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 803
Query: 152 VYCGL 156
+ C +
Sbjct: 804 ICCSV 808
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 258 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 315
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323
Query: 316 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 353
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 324 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371
Score = 34.7 bits (78), Expect = 0.18
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 21/97 (21%)
Query: 98 RCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLK 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 629 RCP------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRRM 675
Query: 158 TCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 192
C C P +V CC C D LS + H +G+
Sbjct: 676 VC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 706
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 19/155 (12%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384
Query: 89 VHIPHLCCPRCP--DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 144
+ + H CC C D +N + + C +G R+ N +
Sbjct: 385 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 441
Query: 145 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
C+EG YC T V+ P S +C+
Sbjct: 442 DECAEGRHYCRENT-------MCVNTPGSFMCICK 469
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 259 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 312
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386
Query: 313 KIDGKCCKVCPG 324
+ CCKVC G
Sbjct: 387 -LSHSCCKVCKG 397
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 54.3 bits (129), Expect = 2e-07
Identities = 19/37 (51%), Positives = 25/37 (67%)
Query: 142 CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 178
CT C C +G V C ++ CP TCA PV++P +CC VC
Sbjct: 1434 CTICECKDGQVTCFVEACPPATCAVPVNIPGACCPVC 1470
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99
C C C + G V C CP C PV+IP CCP C
Sbjct: 1434 CTICECKD-GQVTCFVEACPPATCAVPVNIPGACCPVC 1470
Score = 38.1 bits (87), Expect = 0.017
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319
CV G GES H N + C +C C + C CP C P I G CC
Sbjct: 1415 CVDAG-----GES-HANNTKWKKDACTICECKDGQVTCFVEACPPA-TCAVPVNIPGACC 1467
Query: 320 KVCPGKKAKEE 330
VC K+A+E+
Sbjct: 1468 PVCLQKRAEEK 1478
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 45.8 bits (107), Expect = 8e-05
Identities = 18/41 (43%), Positives = 21/41 (51%)
Query: 142 CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDG 182
CT C C G V C ++ CP C P V +CC VCR G
Sbjct: 1414 CTHCICESGQVTCVVEICPPAPCPSPELVKGTCCPVCRDRG 1454
Score = 40.0 bits (92), Expect = 0.004
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPD 101
C +CIC E+G V C CP C SP + CCP C D
Sbjct: 1414 CTHCIC-ESGQVTCVVEICPPAPCPSPELVKGTCCPVCRD 1452
Score = 34.7 bits (78), Expect = 0.18
Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 1/49 (2%)
Query: 284 ECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELP 332
+C C C + C CP PC P+ + G CC VC + + P
Sbjct: 1413 DCTHCICESGQVTCVVEICPPA-PCPSPELVKGTCCPVCRDRGMPSDSP 1460
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 13/85 (15%)
Query: 104 PPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLT 163
PP +++ C +G + E +V + CT C+C + C TCP T
Sbjct: 311 PPKTRNMSA--CWQDGRFFAENETWVVDS---------CTTCTCKKFKTICHQITCPPAT 359
Query: 164 CAFPVSVPDSCCRVC--RGDGELSW 186
CA P V CC C DGE W
Sbjct: 360 CASPSFVEGECCPSCLHSVDGEEGW 384
Score = 43.5 bits (101), Expect = 4e-04
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 253 KHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQ 312
K ++ C +G+ ++ E+W + C CTC K C +I CP C P
Sbjct: 313 KTRNMSACWQDGRFFAENETWV-------VDSCTTCTCKKFKTICHQITCPPA-TCASPS 364
Query: 313 KIDGKCCKVC 322
++G+CC C
Sbjct: 365 FVEGECCPSC 374
Score = 37.0 bits (84), Expect = 0.037
Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSL 103
C C C + +C ++ CP C SP + CCP C S+
Sbjct: 338 CTTCTCKKF-KTICHQITCPPATCASPSFVEGECCPSCLHSV 378
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/169 (23%), Positives = 74/169 (43%), Gaps = 27/169 (15%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKI--DGK 317
C+ G T + W P C C C+ + C + C +P + PQ + +G+
Sbjct: 103 CLVKGITMYNKAVWSPE-------PCTTCLCSDGRVLCDETMC---HPQRCPQTVIPEGE 152
Query: 318 CCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEV 377
CC VC + L G + +++ F G+ + E E T + + PPQV +
Sbjct: 153 CCPVCSATVSYSLLSGIALNDRNEFSGDSS---------EQREPTNLLHKQLP-PPQVGM 202
Query: 378 HVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQ 426
+RK LQ E++ + E+ K T + +Q ++++EG+++
Sbjct: 203 D-RIVRKEALQSEEDEEVKEEDTEQ----KRETPESRNQGQLYSEGDSR 246
Score = 38.1 bits (87), Expect = 0.017
Identities = 16/40 (40%), Positives = 17/40 (42%)
Query: 139 PNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 178
P CT C CS+G V C C C V CC VC
Sbjct: 118 PEPCTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVC 157
Score = 33.9 bits (76), Expect = 0.32
Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99
C C+CS+ G VLC C C V CCP C
Sbjct: 121 CTTCLCSD-GRVLCDETMCHPQRCPQTVIPEGECCPVC 157
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319
CV NG Y + W P C +C C+ K C + C C + +G+CC
Sbjct: 40 CVQNGLRYHDRDVWKPE-------PCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECC 92
Query: 320 KVCP 323
VCP
Sbjct: 93 PVCP 96
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 10/77 (12%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH-LC 95
C+ +Y + W P EP C C+C +NG VLC V C +P C
Sbjct: 40 CVQNGLRYHDRDVWKP--EP-----CRICVC-DNGKVLCDDVICDETKNCPGAEVPEGEC 91
Query: 96 CPRCPD-SLPPVNNKVT 111
CP CPD S P + + T
Sbjct: 92 CPVCPDGSESPTDQETT 108
Score = 33.5 bits (75), Expect = 0.41
Identities = 21/84 (25%), Positives = 31/84 (36%), Gaps = 17/84 (20%)
Query: 101 DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCP 160
+ +PP+ +C NG Y +++ +P C C C G V C C
Sbjct: 33 EDIPPI-------TCVQNGLRYHDRDVW---------KPEPCRICVCDNGKVLCDDVICD 76
Query: 161 KLTCAFPVSVPD-SCCRVCRGDGE 183
+ VP+ CC VC E
Sbjct: 77 ETKNCPGAEVPEGECCPVCPDGSE 100
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 43.9 bits (102), Expect = 3e-04
Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 17/91 (18%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319
CV +G+ Y+ + W P C +C C+ C I C + C P+ G+CC
Sbjct: 34 CVQDGQRYNDKDVWKPE-------PCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECC 86
Query: 320 KVC----------PGKKAKEELPGQSFDNKG 340
+C PG K ++ PG D G
Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVG 117
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 9/68 (13%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPVHIPHLC 95
C+ ++Y + W P EP C C+C + G VLC + C +V CLSP C
Sbjct: 34 CVQDGQRYNDKDVWKP--EP-----CRICVC-DTGTVLCDDIICEDVKDCLSPEIPFGEC 85
Query: 96 CPRCPDSL 103
CP CP L
Sbjct: 86 CPICPTDL 93
Score = 30.4 bits (67), Expect = 3.5
Identities = 17/69 (24%), Positives = 25/69 (36%), Gaps = 10/69 (14%)
Query: 114 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP-D 172
SC +G Y +++ +P C C C G V C C + +P
Sbjct: 33 SCVQDGQRYNDKDVW---------KPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFG 83
Query: 173 SCCRVCRGD 181
CC +C D
Sbjct: 84 ECCPICPTD 92
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 7/63 (11%)
Query: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319
C NG+ Y + + W P C +C C+ C KI C + C P G+CC
Sbjct: 41 CTQNGQMYLNRDIWKP-------APCQICVCDNGAILCDKIECQDVLDCADPVTPPGECC 93
Query: 320 KVC 322
VC
Sbjct: 94 PVC 96
Score = 40.8 bits (94), Expect = 0.003
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 34 ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNV-HCLSPVHIP 92
E C + Y + W P C C+C +NG +LC ++ C +V C PV P
Sbjct: 38 EIACTQNGQMYLNRDIWKP-------APCQICVC-DNGAILCDKIECQDVLDCADPVTPP 89
Query: 93 HLCCPRC 99
CCP C
Sbjct: 90 GECCPVC 96
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)
Query: 114 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK-LTCAFPVSVPD 172
+C NG Y + +++ +P C C C G + C C L CA PV+ P
Sbjct: 40 ACTQNGQMYLNRDIW---------KPAPCQICVCDNGAILCDKIECQDVLDCADPVTPPG 90
Query: 173 SCCRVC 178
CC VC
Sbjct: 91 ECCPVC 96
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 43.5 bits (101), Expect = 4e-04
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%)
Query: 252 NKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 311
N+ + +C NG Y + E W + C C C + CKK+ CP PC
Sbjct: 310 NELRRPPLCYHNGVQYRNNEEWT-------VDSCTECHCQNSVTICKKVSCP-IMPCSNA 361
Query: 312 QKIDGKCCKVC 322
DG+CC C
Sbjct: 362 TVPDGECCPRC 372
Score = 37.4 bits (85), Expect = 0.029
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 8/63 (12%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C +YR E W + C C C +N +C +V CP + C + CC
Sbjct: 318 CYHNGVQYRNNEEWT-------VDSCTECHC-QNSVTICKKVSCPIMPCSNATVPDGECC 369
Query: 97 PRC 99
PRC
Sbjct: 370 PRC 372
Score = 37.4 bits (85), Expect = 0.029
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 11/65 (16%)
Query: 115 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPD-S 173
C +NG Y++ E + + CT+C C C +CP + C+ +VPD
Sbjct: 318 CYHNGVQYRNNEEWTVDS---------CTECHCQNSVTICKKVSCPIMPCS-NATVPDGE 367
Query: 174 CCRVC 178
CC C
Sbjct: 368 CCPRC 372
>gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
Length = 381
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%)
Query: 113 KSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK------LTCAF 166
+ CEYN YQ+GE F QPN QC+C +G V C + CP+ L C
Sbjct: 98 RPCEYNSRIYQNGESF---------QPNCKHQCTCIDGAVGC-IPLCPQELSLPNLGCPN 147
Query: 167 P--VSVPDSCCR--VCRGD 181
P V V CC VC D
Sbjct: 148 PRLVKVTGQCCEEWVCDED 166
Score = 33.9 bits (76), Expect = 0.32
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 17/87 (19%)
Query: 257 GQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQEC-----KKIHCPNRYPCKYP 311
G+ C N + Y +GES+ PN + CTC C +++ PN C P
Sbjct: 97 GRPCEYNSRIYQNGESFQPNCKH-------QCTCIDGAVGCIPLCPQELSLPN-LGCPNP 148
Query: 312 Q--KIDGKCCK--VCPGKKAKEELPGQ 334
+ K+ G+CC+ VC K+ + Q
Sbjct: 149 RLVKVTGQCCEEWVCDEDSIKDPMEDQ 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,585,964
Number of Sequences: 37866
Number of extensions: 1110378
Number of successful extensions: 3596
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 2926
Number of HSP's gapped (non-prelim): 554
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.