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Search of human proteins with 221316561
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
(458 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 995 0.0
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 988 0.0
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 982 0.0
gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] 626 e-179
gi|40353769 chordin-like 2 [Homo sapiens] 309 4e-84
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 104 2e-22
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 102 6e-22
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 97 4e-20
gi|37693519 BMP-binding endothelial regulator precursor protein ... 95 2e-19
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 77 4e-14
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa... 76 7e-14
gi|30089980 chordin [Homo sapiens] 74 2e-13
gi|108773804 Fraser syndrome 1 [Homo sapiens] 71 2e-12
gi|122937446 von Willebrand factor C domain-containing protein 2... 69 1e-11
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 60 4e-09
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 60 4e-09
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 59 1e-08
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 59 1e-08
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 59 1e-08
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 59 1e-08
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 59 1e-08
gi|109150416 peroxidasin [Homo sapiens] 54 2e-07
gi|126517478 peroxidasin homolog-like [Homo sapiens] 46 8e-05
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 45 1e-04
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 45 1e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 44 3e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 44 3e-04
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 44 3e-04
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 44 4e-04
gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] 42 0.001
>gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
Length = 458
Score = 995 bits (2572), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG 120
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG 120
Query: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR
Sbjct: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
Query: 181 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 240
GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ
Sbjct: 181 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 240
Query: 241 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 300
QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK
Sbjct: 241 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 300
Query: 301 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 360
IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG
Sbjct: 301 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 360
Query: 361 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 420
ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI
Sbjct: 361 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 420
Query: 421 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 458
FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC
Sbjct: 421 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 458
>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
Length = 457
Score = 988 bits (2555), Expect = 0.0
Identities = 457/458 (99%), Positives = 457/458 (99%), Gaps = 1/458 (0%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG 120
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP DSLPPVNNKVTSKSCEYNG
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP-DSLPPVNNKVTSKSCEYNG 119
Query: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR
Sbjct: 120 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
Query: 181 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 240
GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ
Sbjct: 180 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 239
Query: 241 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 300
QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK
Sbjct: 240 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 299
Query: 301 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 360
IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG
Sbjct: 300 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 359
Query: 361 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 420
ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI
Sbjct: 360 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 419
Query: 421 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 458
FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC
Sbjct: 420 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 457
>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
Length = 456
Score = 982 bits (2538), Expect = 0.0
Identities = 456/458 (99%), Positives = 456/458 (99%), Gaps = 2/458 (0%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG 120
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP DSLPPVNNKVTSKSCEYNG
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP-DSLPPVNNKVTSKSCEYNG 119
Query: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR
Sbjct: 120 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 179
Query: 181 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 240
GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ
Sbjct: 180 GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQ 239
Query: 241 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 300
QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK
Sbjct: 240 QASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKK 299
Query: 301 IHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDG 360
IHCPNRYPCKYPQKIDGKCCKVCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDG
Sbjct: 300 IHCPNRYPCKYPQKIDGKCCKVCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDG 358
Query: 361 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 420
ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI
Sbjct: 359 ETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKI 418
Query: 421 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 458
FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC
Sbjct: 419 FTEGEAQISQMCSSRVCRTELEDLVKVLYLERSEKGHC 456
>gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]
Length = 377
Score = 626 bits (1615), Expect = e-179
Identities = 295/317 (93%), Positives = 297/317 (93%), Gaps = 2/317 (0%)
Query: 143 CTQCSCSE-GNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR 201
C C CSE GNV C CP + C PV +P CC C GDGELSWEHSDGDIFRQPANR
Sbjct: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANR 121
Query: 202 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 261
EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC
Sbjct: 122 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 181
Query: 262 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 321
VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK
Sbjct: 182 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCK 241
Query: 322 VCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 381
VCPGKKAK ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW
Sbjct: 242 VCPGKKAK-ELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVW 300
Query: 382 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 441
TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL
Sbjct: 301 TIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQISQMCSSRVCRTEL 360
Query: 442 EDLVKVLYLERSEKGHC 458
EDLVKVLYLERSEKGHC
Sbjct: 361 EDLVKVLYLERSEKGHC 377
Score = 238 bits (608), Expect = 6e-63
Identities = 126/245 (51%), Positives = 141/245 (57%), Gaps = 64/245 (26%)
Query: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV
Sbjct: 1 MRKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLV 60
Query: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDS------------LPPVN 108
YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCP D P N
Sbjct: 61 YCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPAN 120
Query: 109 NKVTSK--------------------------------SCEYNGTTYQ--------HGEL 128
+ S + +GT Q HG++
Sbjct: 121 REARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQV 180
Query: 129 FVAEGLF----QNRQPN-------QCTQCSCSEGNVYCGLKTCP-KLTCAFPVSVPDSCC 176
V+ G ++ PN +C C+C+ C CP + C +P + CC
Sbjct: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240
Query: 177 RVCRG 181
+VC G
Sbjct: 241 KVCPG 245
Score = 60.1 bits (144), Expect = 4e-09
Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 256 KHGQV-CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQE-CKKIHCPNRYPCKYPQ 313
KH + C+ K Y GE WHP L +G+V CV C C+ C ++ CPN + C P
Sbjct: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPV 89
Query: 314 KIDGKCCKVCPG 325
I CC CPG
Sbjct: 90 HIPHLCCPRCPG 101
>gi|40353769 chordin-like 2 [Homo sapiens]
Length = 451
Score = 309 bits (791), Expect = 4e-84
Identities = 149/361 (41%), Positives = 201/361 (55%), Gaps = 26/361 (7%)
Query: 34 ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH 93
+ +C+F K+Y GE WHPYLEP GL+YC+ C CSE +V C R+ CP VHC PV P
Sbjct: 30 DMFCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQ 89
Query: 94 LCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNV 153
CCP+C E P + KSC++NGT YQHGE+F A LF +R PNQC CSC+EG +
Sbjct: 90 QCCPKCVEPHTPS-GLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQI 148
Query: 154 YCGLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYD 213
YCGL TCP+ C P+ +PDSCC+ C+ + E SD + ++ S H +
Sbjct: 149 YCGLTTCPEPGCPAPLPLPDSCCQACKDEAS---EQSDEE--------DSVQSLHGVRHP 197
Query: 214 PPPSRQAGGLSRFPGARSHRGALMD---------SQQASGTIVQIVINNKHKHGQVCVSN 264
P G R PG + G + A T V+IV+ KHK + CV
Sbjct: 198 QDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHK--KACVHG 255
Query: 265 GKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCP 324
GKTYSHGE WHP RAFG + C+LCTC +Q+C+++ CP YPC++P+K+ GKCCK+CP
Sbjct: 256 GKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKICP 315
Query: 325 GKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEVHVWTIR 384
KA PG S + + + + R+ ALE E VE+++W +
Sbjct: 316 EDKAD---PGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEASDLVEIYLWKLV 372
Query: 385 K 385
K
Sbjct: 373 K 373
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 104 bits (259), Expect = 2e-22
Identities = 84/301 (27%), Positives = 106/301 (35%), Gaps = 62/301 (20%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 424 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 477
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C SC Y+ Y +G+ F + C C C +G V C
Sbjct: 478 PSCD--------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCS 516
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYD 213
L CP TCA P S P CC C D L E DG+ F P + +E R +H
Sbjct: 517 LVDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQ 575
Query: 214 PPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGES 273
P P +A PG SG C GK Y G
Sbjct: 576 PRPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGAD 612
Query: 274 W-HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEEL 332
+ HP+ C LC C +C C PC P + G+CC CP A
Sbjct: 613 FPHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCPAAPAPAGC 665
Query: 333 P 333
P
Sbjct: 666 P 666
Score = 96.3 bits (238), Expect = 5e-20
Identities = 78/294 (26%), Positives = 106/294 (36%), Gaps = 69/294 (23%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + Y GE + P C C C E G + C++ CP C P CC
Sbjct: 138 CSQNGQTYGNGETFSPDA-------CTTCRCLE-GTITCNQKPCPRGPCPEP----GACC 185
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C C+Y G Y+ G F++ N C QC+C V C
Sbjct: 186 PHC-------------KPGCDYEGQLYEEGVTFLSSS-------NPCLQCTCLRSRVRCM 225
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRG--DGELSWEHSDGDIFRQPANREARHSYHRSHYDP 214
CP C PV P CC C+G +G WEH G + P + R +
Sbjct: 226 ALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQ 282
Query: 215 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE-- 272
R+ L +P ++ GT + C NG+ + GE
Sbjct: 283 CRQRECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPV 323
Query: 273 -SWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 325
S P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 324 GSGDP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 367
Score = 89.0 bits (219), Expect = 8e-18
Identities = 88/313 (28%), Positives = 120/313 (38%), Gaps = 61/313 (19%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 310 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 361
Query: 96 CPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYC 155
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 362 CPVCD--------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSC 401
Query: 156 GLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 215
+ CP CA P S C C DGE E ++G + +P R + D
Sbjct: 402 EEQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGV 453
Query: 216 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWH 275
P + G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 454 P--KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-- 501
Query: 276 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE--LP 333
C C C C + CP C PQ G+CC CP +EE +
Sbjct: 502 ---------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVD 551
Query: 334 GQSFDNKGYFCGE 346
G+SF + C E
Sbjct: 552 GESFSHPRDPCQE 564
Score = 73.6 bits (179), Expect = 4e-13
Identities = 75/307 (24%), Positives = 109/307 (35%), Gaps = 63/307 (20%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHI 91
H + C ++ + Y G + P C+ C C + V C ++CP C PV
Sbjct: 187 HCKPGCDYEGQLYEEGVTFLSSSNP-----CLQCTCLRS-RVRCMALKCPPSPCPEPVLR 240
Query: 92 PHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEG 151
P CCP C + C G+ ++HG+ + G + C C C EG
Sbjct: 241 PGHCCPTC--------------QGCTEGGSHWEHGQEWTTPG-------DPCRICRCLEG 279
Query: 152 NVYCGLKTCPKLTCAFPV-SVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRS 210
++ C + C L C +P +P +CC VC G EH G +P S+ R
Sbjct: 280 HIQCRQRECASL-CPYPARPLPGTCCPVCDGCFLNGREHRSG----EPVGSGDPCSHCRC 334
Query: 211 HYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSH 270
S Q L P H G + G + C G Y
Sbjct: 335 ---ANGSVQCEPLPCPPVPCRHPGKI------PGQCCPVC--------DGCEYQGHQYQS 377
Query: 271 GESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE 330
E++ R CV C+C + C++ CP PC P + C C
Sbjct: 378 QETFRLQERGL----CVRCSCQAGEVSCEEQECPVT-PCALPAS-GRQLCPAC------- 424
Query: 331 ELPGQSF 337
EL G+ F
Sbjct: 425 ELDGEEF 431
Score = 72.8 bits (177), Expect = 6e-13
Identities = 67/292 (22%), Positives = 97/292 (33%), Gaps = 81/292 (27%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + G RW P C C+C + HC H+PH
Sbjct: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
+ C NG TY +GE F P+ CT C C EG + C
Sbjct: 136 -----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLEGTITCN 169
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 216
K CP+ C P + C C +G+L + +G F +N + + RS
Sbjct: 170 QKPCPRGPCPEPGACCPHCKPGCDYEGQL---YEEGVTFLSSSNPCLQCTCLRS------ 220
Query: 217 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKH--KHGQVCVSNGKTYSHGESW 274
R M + + V+ H Q C G + HG+ W
Sbjct: 221 ----------------RVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEW 264
Query: 275 HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQK-IDGKCCKVCPG 325
C +C C +C++ C + C YP + + G CC VC G
Sbjct: 265 -----TTPGDPCRICRCLEGHIQCRQRECASL--CPYPARPLPGTCCPVCDG 309
Score = 70.5 bits (171), Expect = 3e-12
Identities = 72/303 (23%), Positives = 101/303 (33%), Gaps = 77/303 (25%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C+ +++ + GE + +P C C C E G+ C CP C P +P CC
Sbjct: 542 CILEEEVFVDGESFSHPRDP-----CQECRCQE-GHAHCQPRPCPRAPCAHP--LPGTCC 593
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C + G Y G F + C C C GNV C
Sbjct: 594 PN-------------DCSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCL 633
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP- 215
+ C L C PV +P CC C + G A H+ H+ ++ PP
Sbjct: 634 ARRCVPLPCPEPVLLPGECCPQCPAAPAPAGCPRPG----------AAHARHQEYFSPPG 683
Query: 216 -PSRQA----GGLS-------RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVS 263
P R+ G +S P A +G S C+
Sbjct: 684 DPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG------------------CLY 725
Query: 264 NGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
GK ++ GE + A C LC C C+ C C +P + G CC C
Sbjct: 726 QGKEFASGERFPSPTAA-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDC 777
Query: 324 PGK 326
G+
Sbjct: 778 DGE 780
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 102 bits (255), Expect = 6e-22
Identities = 82/292 (28%), Positives = 104/292 (35%), Gaps = 62/292 (21%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C +++ G +W P P C C+C ++G C V CP C P P CC
Sbjct: 366 CELDGEEFAEGVQWEPDGRP-----CTACVC-QDGVPKCGAVLCPPAPCQHPTQPPGACC 419
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C SC Y+ Y +G+ F + C C C +G V C
Sbjct: 420 PSCD--------------SCTYHSQVYANGQNFTDAD-------SPCHACHCQDGTVTCS 458
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWE-HSDGDIFRQPAN--REARHSYHRSHYD 213
L CP TCA P S P CC C D L E DG+ F P + +E R +H
Sbjct: 459 LVDCPPTTCARPQSGPGQCCPRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQ 517
Query: 214 PPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGES 273
P P +A PG SG C GK Y G
Sbjct: 518 PRPCPRAPCAHPLPGT-------CCPNDCSG----------------CAFGGKEYPSGAD 554
Query: 274 W-HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCP 324
+ HP+ C LC C +C C PC P + G+CC CP
Sbjct: 555 FPHPS------DPCRLCRCLSGNVQCLARRCV-PLPCPEPVLLPGECCPQCP 599
Score = 89.0 bits (219), Expect = 8e-18
Identities = 88/313 (28%), Positives = 120/313 (38%), Gaps = 61/313 (19%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVY-CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLC 95
C +++R GE P G C +C C+ NG+V C + CP V C P IP C
Sbjct: 252 CFLNGREHRSGE-------PVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQC 303
Query: 96 CPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYC 155
CP C CEY G YQ E F + ++ C +CSC G V C
Sbjct: 304 CPVCD--------------GCEYQGHQYQSQETF------RLQERGLCVRCSCQAGEVSC 343
Query: 156 GLKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP 215
+ CP CA P S C C DGE E ++G + +P R + D
Sbjct: 344 EEQECPVTPCALPAS-GRQLCPACELDGE---EFAEG-VQWEPDGRPCTACVCQ---DGV 395
Query: 216 PSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWH 275
P + G + P H Q G + + H QV +NG+ ++ +S
Sbjct: 396 P--KCGAVLCPPAPCQH------PTQPPGACCPSCDSCTY-HSQV-YANGQNFTDADS-- 443
Query: 276 PNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE--LP 333
C C C C + CP C PQ G+CC CP +EE +
Sbjct: 444 ---------PCHACHCQDGTVTCSLVDCPPT-TCARPQSGPGQCCPRCPDCILEEEVFVD 493
Query: 334 GQSFDNKGYFCGE 346
G+SF + C E
Sbjct: 494 GESFSHPRDPCQE 506
Score = 88.6 bits (218), Expect = 1e-17
Identities = 72/292 (24%), Positives = 101/292 (34%), Gaps = 81/292 (27%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + G RW P C C+C + HC H+PH
Sbjct: 96 CWGLGRAWPEGARWEPDA-------CTACVCQDGA-----------AHCGPQAHLPHC-- 135
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
+ C NG TY +GE F P+ CT C C G V C
Sbjct: 136 -----------------RGCSQNGQTYGNGETF---------SPDACTTCRCLTGAVQCQ 169
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPP 216
+C +L C + P CC +C +G WEH G + P + R +
Sbjct: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEH--GQEWTTPGD-PCRICRCLEGHIQCR 226
Query: 217 SRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGE---S 273
R+ L +P ++ GT + C NG+ + GE S
Sbjct: 227 QRECASLCPYP-----------ARPLPGTCCPVC--------DGCFLNGREHRSGEPVGS 267
Query: 274 WHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG 325
P C C C +C+ + CP PC++P KI G+CC VC G
Sbjct: 268 GDP---------CSHCRCANGSVQCEPLPCP-PVPCRHPGKIPGQCCPVCDG 309
Score = 81.3 bits (199), Expect = 2e-15
Identities = 70/278 (25%), Positives = 107/278 (38%), Gaps = 59/278 (21%)
Query: 47 GERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH-IPHLCCPRCPEDSLP 105
G+ W +P C C C E G++ C + C ++ C P +P CCP C
Sbjct: 203 GQEWTTPGDP-----CRICRCLE-GHIQCRQRECASL-CPYPARPLPGTCCPVCD----- 250
Query: 106 PVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTC 165
C NG ++ GE V G + C+ C C+ G+V C CP + C
Sbjct: 251 ---------GCFLNGREHRSGEP-VGSG-------DPCSHCRCANGSVQCEPLPCPPVPC 293
Query: 166 AFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSR 225
P +P CC VC G ++ + FR + R R S QAG +S
Sbjct: 294 RHPGKIPGQCCPVCDGCEYQGHQYQSQETFR----LQERGLCVRC------SCQAGEVS- 342
Query: 226 FPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVE 285
+ Q+ T + + + + C +G+ ++ G W P+ R
Sbjct: 343 -----------CEEQECPVTPCALPASGR-QLCPACELDGEEFAEGVQWEPDGR-----P 385
Query: 286 CVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
C C C +C + CP PC++P + G CC C
Sbjct: 386 CTACVCQDGVPKCGAVLCPPA-PCQHPTQPPGACCPSC 422
Score = 75.1 bits (183), Expect = 1e-13
Identities = 73/312 (23%), Positives = 107/312 (34%), Gaps = 74/312 (23%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + Y + + EP L C+ G V C R C C P+ CC
Sbjct: 719 CEYLGESYLSNQEFPDPREPCNLCTCLG------GFVTCGRRPCEPPGCSHPLIPSGHCC 772
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C + C Y+G T GE + C+ C+C EG++ C
Sbjct: 773 PTC--------------QGCRYHGVTTASGE------TLPDPLDPTCSLCTCQEGSMRCQ 812
Query: 157 LKTCPKLTCAFPVSVPDSC--CRVCRGDGELSWEHSDGDIFRQPAN-------REARHSY 207
K CP C P P C C C G EH DG+ F PA + + S
Sbjct: 813 KKPCPPALCPHPSPGPCFCPVCHSCLSQGR---EHQDGEEFEGPAGSCEWCRCQAGQVSC 869
Query: 208 HRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKT 267
R P P + + RG+ + C+++G+
Sbjct: 870 VRLQCPPLPCKL---------QVTERGSCCPRCRG------------------CLAHGEE 902
Query: 268 YSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPG-- 325
+ G W P A C C C+ C +I C + C P++ CC C
Sbjct: 903 HPEGSRWVPPDSA-----CSSCVCHEGVVTCARIQCIS--SCAQPRQGPHDCCPQCSDCE 955
Query: 326 KKAKEELPGQSF 337
+ ++ PG+SF
Sbjct: 956 HEGRKYEPGESF 967
Score = 73.9 bits (180), Expect = 3e-13
Identities = 73/300 (24%), Positives = 103/300 (34%), Gaps = 65/300 (21%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C++Q K++ GER+ P C C+C E G+V C C C P CC
Sbjct: 662 CLYQGKEFASGERF-----PSPTAACHLCLCWE-GSVSCEPKACAPALCPFPARGD--CC 713
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C CEY G +Y + F R+P C C+C G V CG
Sbjct: 714 PDCD--------------GCEYLGESYLSNQEFP-----DPREP--CNLCTCLGGFVTCG 752
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANR-----EARHSYHRSH 211
+ C C+ P+ CC C+G + G+ P + + R
Sbjct: 753 RRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQ 812
Query: 212 YDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHG 271
P P P H + G V ++ C+S G+ + G
Sbjct: 813 KKPCP----------PALCPH--------PSPGPCFCPVCHS-------CLSQGREHQDG 847
Query: 272 ESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEE 331
E + + C C C + C ++ CP PCK G CC C G A E
Sbjct: 848 EEFEGPAGS-----CEWCRCQAGQVSCVRLQCP-PLPCKLQVTERGSCCPRCRGCLAHGE 901
Score = 71.6 bits (174), Expect = 1e-12
Identities = 81/308 (26%), Positives = 98/308 (31%), Gaps = 75/308 (24%)
Query: 49 RWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVN 108
R Y P G C C+C + G+V C R+ CP C P P CCP C
Sbjct: 613 RHQEYFSPPGDP-CRRCLCLD-GSVSCQRLPCPPAPCAHPRQGP--CCPSCD-------- 660
Query: 109 NKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFP 168
C Y G + GE F + C C C EG+V C K C C FP
Sbjct: 661 ------GCLYQGKEFASGERFPSPTA-------ACHLCLCWEGSVSCEPKACAPALCPFP 707
Query: 169 VSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRF-- 226
CC C G L + F P P L F
Sbjct: 708 AR--GDCCPDCDGCEYLGESYLSNQEFPDPRE---------------PCNLCTCLGGFVT 750
Query: 227 -------PGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLR 279
P SH L+ S T Q C +G T + GE+ L
Sbjct: 751 CGRRPCEPPGCSH--PLIPSGHCCPTC------------QGCRYHGVTTASGETLPDPLD 796
Query: 280 AFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKC-CKVCPG--KKAKEELPGQS 336
C LCTC C+K CP P P G C C VC + +E G+
Sbjct: 797 P----TCSLCTCQEGSMRCQKKPCP---PALCPHPSPGPCFCPVCHSCLSQGREHQDGEE 849
Query: 337 FDNKGYFC 344
F+ C
Sbjct: 850 FEGPAGSC 857
Score = 70.1 bits (170), Expect = 4e-12
Identities = 72/302 (23%), Positives = 100/302 (33%), Gaps = 80/302 (26%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C+ +++ + GE + +P C C C E G+ C CP C P +P CC
Sbjct: 484 CILEEEVFVDGESFSHPRDP-----CQECRCQE-GHAHCQPRPCPRAPCAHP--LPGTCC 535
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C + G Y G F + C C C GNV C
Sbjct: 536 PN-------------DCSGCAFGGKEYPSGADFP-------HPSDPCRLCRCLSGNVQCL 575
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPP- 215
+ C L C PV +P CC C +P A H+ H+ ++ PP
Sbjct: 576 ARRCVPLPCPEPVLLPGECCPQCPAPAGCP----------RPG---AAHARHQEYFSPPG 622
Query: 216 -PSRQA----GGLS-------RFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVS 263
P R+ G +S P A +G S C+
Sbjct: 623 DPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDG------------------CLY 664
Query: 264 NGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
GK ++ GE + A C LC C C+ C C +P + G CC C
Sbjct: 665 QGKEFASGERFPSPTAA-----CHLCLCWEGSVSCEPKACAPAL-CPFPAR--GDCCPDC 716
Query: 324 PG 325
G
Sbjct: 717 DG 718
Score = 66.6 bits (161), Expect = 4e-11
Identities = 73/300 (24%), Positives = 107/300 (35%), Gaps = 65/300 (21%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C+ +++ G RW P C +C+C E G V C+R++C + C P PH CC
Sbjct: 896 CLAHGEEHPEGSRWVPPDSA-----CSSCVCHE-GVVTCARIQCIS-SCAQPRQGPHDCC 948
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQP--NQCTQCSCS---EG 151
P+C + CE+ G Y+ GE F QP + C C C EG
Sbjct: 949 PQCSD--------------CEHEGRKYEPGESF---------QPGADPCEVCICEPQPEG 985
Query: 152 --NVYCGLKTCPKLTCAFPVSV----PDSCCRVCRGDGELSWEHSDGDIFRQPANREARH 205
++ C + CP L P + P CC C E S+G + + A + +
Sbjct: 986 PPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTC---AEALSNCSEGLLGSELAPPDPCY 1042
Query: 206 SYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNG 265
+ QA P L + G+ + Q CV G
Sbjct: 1043 TCQCQDLTWLCIHQACPELSCP--------LSERHTPPGSCCPVC----RAPTQSCVHQG 1090
Query: 266 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKIDGKCCKVC 323
+ + GE W + C C+C C+ C + P K P G CC C
Sbjct: 1091 REVASGERW-------TVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143
Score = 57.4 bits (137), Expect = 3e-08
Identities = 44/164 (26%), Positives = 66/164 (40%), Gaps = 28/164 (17%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C+ Q ++++ GE + P G C C C + G V C R++CP + C V CC
Sbjct: 837 CLSQGREHQDGEEFEG---PAGS--CEWCRC-QAGQVSCVRLQCPPLPCKLQVTERGSCC 890
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
PRC + C +G + G +V + C+ C C EG V C
Sbjct: 891 PRC--------------RGCLAHGEEHPEGSRWVPPD-------SACSSCVCHEGVVTCA 929
Query: 157 LKTCPKLTCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPAN 200
C +CA P P CC C ++ G+ F+ A+
Sbjct: 930 RIQCIS-SCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGAD 972
Score = 39.7 bits (91), Expect = 0.006
Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 8/88 (9%)
Query: 257 HGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKID 316
H + C NG+TY +GE++ P+ C C C +C+ C + C
Sbjct: 134 HCRGCSQNGQTYGNGETFSPD-------ACTTCRCLTGAVQCQGPSC-SELNCLESCTPP 185
Query: 317 GKCCKVCPGKKAKEELPGQSFDNKGYFC 344
G+CC +C + GQ + G C
Sbjct: 186 GECCPICCTEGGSHWEHGQEWTTPGDPC 213
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 96.7 bits (239), Expect = 4e-20
Identities = 80/293 (27%), Positives = 112/293 (38%), Gaps = 38/293 (12%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGT 121
C C C NG +C+ + CP C +P P CCP C +D + T C G
Sbjct: 626 CRECYCL-NGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPG- 683
Query: 122 TYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC-- 179
GE FV EG N + CTQC+C G V C + CP L C P DSCC C
Sbjct: 684 ----GEYFV-EGETWNI--DSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTD 736
Query: 180 --------RGDGELSW-EHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGAR 230
R + ++ ++ +GDIF + + D S + P
Sbjct: 737 QPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFS---ESCPSVS 793
Query: 231 SHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCT 290
R L G I + VC +GK Y+ E W + C C
Sbjct: 794 CERPVL-----RKGQCCPYCIEDTIPKKVVCHFSGKAYADEERW-------DLDSCTHCY 841
Query: 291 CNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKE--ELPGQSFDNKG 341
C + C + CP PC P ++G CC +CP E +P + +++G
Sbjct: 842 CLQGQTLCSTVSCP-PLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRG 893
Score = 78.6 bits (192), Expect = 1e-14
Identities = 43/136 (31%), Positives = 61/136 (44%), Gaps = 23/136 (16%)
Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDS 103
+ E W P + C +CIC ++ + C CP+V C PV CCP C ED+
Sbjct: 761 FLAAESWKPDV-------CTSCICIDSV-ISCFSESCPSVSCERPVLRKGQCCPYCIEDT 812
Query: 104 LPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKL 163
+P KV C ++G Y E + + CT C C +G C +CP L
Sbjct: 813 IP---KKVV---CHFSGKAYADEERWDLDS---------CTHCYCLQGQTLCSTVSCPPL 857
Query: 164 TCAFPVSVPDSCCRVC 179
C P++V SCC +C
Sbjct: 858 PCVEPINVEGSCCPMC 873
Score = 72.0 bits (175), Expect = 1e-12
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 55 EPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSK 114
E + + C C C +G VLC CP + C +P CCP+C + P ++ S
Sbjct: 691 ETWNIDSCTQCTC-HSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSV 749
Query: 115 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS 174
N G++F+A ++ +P+ CT C C + + C ++CP ++C PV
Sbjct: 750 P---NYCKNDEGDIFLAA---ESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQ 803
Query: 175 CCRVCRGD 182
CC C D
Sbjct: 804 CCPYCIED 811
Score = 67.4 bits (163), Expect = 3e-11
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 24/153 (15%)
Query: 28 EQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS 87
E V ++ C+F + +Y G+ + + C C C + G +C +C ++C
Sbjct: 327 ECVNDTKPACVFNNVEYYDGDMFR-------MDNCRFCRC-QGGVAICFTAQCGEINC-E 377
Query: 88 PVHIPH-LCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQC 146
++P CCP C ED + P NN C NG HG+ + + + CT C
Sbjct: 378 RYYVPEGECCPVC-EDPVYPFNNPA---GCYANGLILAHGDRW---------REDDCTFC 424
Query: 147 SCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 179
C G +C C + TC PV VP CC VC
Sbjct: 425 QCVNGERHCVATVCGQ-TCTNPVKVPGECCPVC 456
Score = 58.9 bits (141), Expect = 9e-09
Identities = 28/73 (38%), Positives = 36/73 (49%), Gaps = 8/73 (10%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C F K Y ERW L C +C C + G LCS V CP + C+ P+++ CC
Sbjct: 819 CHFSGKAYADEERWD-------LDSCTHCYCLQ-GQTLCSTVSCPPLPCVEPINVEGSCC 870
Query: 97 PRCPEDSLPPVNN 109
P CPE +P N
Sbjct: 871 PMCPEMYVPEPTN 883
Score = 45.8 bits (107), Expect = 8e-05
Identities = 62/274 (22%), Positives = 86/274 (31%), Gaps = 44/274 (16%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSL----PPV-----NNKVT 112
C C C NG C C C +PV +P CCP C E ++ PP N +T
Sbjct: 421 CTFCQCV-NGERHCVATVCGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLT 478
Query: 113 SKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG-LKTCPKLTCAFPVSV 171
K C NG H N C C C C K L C F
Sbjct: 479 GKDC-INGFKRDH---------------NGCRTCQCINTEELCSERKQGCTLNCPFGFLT 522
Query: 172 PDSCCRVCR-GDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGAR 230
C +C D + + +H P + +
Sbjct: 523 DAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQ 582
Query: 231 SHRGALM-DSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLC 289
G L+ ++AS + +++ G +G + + ESWH C C
Sbjct: 583 DSHGCLICKCREASASAGPPILS-----GTCLTVDGHHHKNEESWHDG--------CREC 629
Query: 290 TCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
C ++ C I CP C P G+CC C
Sbjct: 630 YCLNGREMCALITCPVP-ACGNPTIHPGQCCPSC 662
Score = 42.4 bits (98), Expect = 9e-04
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 9/63 (14%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320
C +NG +HG+ W + +C C C ++ C C C P K+ G+CC
Sbjct: 403 CYANGLILAHGDRWRED-------DCTFCQCVNGERHCVATVCGQT--CTNPVKVPGECC 453
Query: 321 KVC 323
VC
Sbjct: 454 PVC 456
Score = 42.4 bits (98), Expect = 9e-04
Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 18/126 (14%)
Query: 73 VLCSRVRCPNVHCLSPVHIPHLC-CPRCPEDS---LPPVNNKVTSKSC---------EYN 119
++C + CP + L H +C C +CPE S + P+ + S C
Sbjct: 542 IICDKY-CP-LGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCREASASA 599
Query: 120 GTTYQHGELFVAEGLFQNRQPNQ---CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCC 176
G G +G + + C +C C G C L TCP C P P CC
Sbjct: 600 GPPILSGTCLTVDGHHHKNEESWHDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCC 659
Query: 177 RVCRGD 182
C D
Sbjct: 660 PSCADD 665
Score = 36.6 bits (83), Expect = 0.049
Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 16/88 (18%)
Query: 92 PHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEG 151
P CC D VN+ T +C +N Y G++F + + C C C G
Sbjct: 319 PGKCC-----DVFECVND--TKPACVFNNVEYYDGDMF---------RMDNCRFCRCQGG 362
Query: 152 NVYCGLKTCPKLTCAFPVSVPDSCCRVC 179
C C ++ C CC VC
Sbjct: 363 VAICFTAQCGEINCERYYVPEGECCPVC 390
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 94.7 bits (234), Expect = 2e-19
Identities = 74/293 (25%), Positives = 115/293 (39%), Gaps = 43/293 (14%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C ++ Y +W EP L C + +E+G VRC VHC +P+ +CC
Sbjct: 108 CTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESG------VRCV-VHCKNPLEHLGMCC 160
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P CP C + G YQ GE F EG ++CT+CSC+ G C
Sbjct: 161 PTCP--------------GCVFEGVQYQEGEEFQPEG-------SKCTKCSCTGGRTQCV 199
Query: 157 LKTCPKLTCAFPVS--VPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDP 214
+ CP L+C +S P CC C G ++ +FR + S+ +
Sbjct: 200 REVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDV-YDNGSSFLYDNCTA 258
Query: 215 PPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESW 274
R + + + SH G Q+ G + ++ + +VC K + GE W
Sbjct: 259 CTCRDSTVVCK--RKCSHPGGCDQGQE--GCCEECLLRVPPEDIKVCKFGNKIFQDGEMW 314
Query: 275 HPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGK-CCKVCPGK 326
+ C +C C + EC+ C C + ++ K CC +C K
Sbjct: 315 -------SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/290 (22%), Positives = 99/290 (34%), Gaps = 49/290 (16%)
Query: 62 CVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYN 119
C+ C+C N V C R +CP + C + CC +C K C Y
Sbjct: 67 CIMCVCL-NKEVTCKREKCPVLSRDCALAIKQRGACCEQC--------------KGCTYE 111
Query: 120 GTTYQHGELFVAEGLFQNRQPNQ-CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRV 178
G TY F+ + P + C C EG V C + C P+ CC
Sbjct: 112 GNTYNSS--------FKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPT 162
Query: 179 CRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSH--RGAL 236
C G ++ +G+ F+ ++ + S R+ + P SH G
Sbjct: 163 CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV--REVCPILSCPQHLSHIPPGQC 220
Query: 237 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQ 296
+ + + C+ Y +G S F C CTC +
Sbjct: 221 CPKCLGQRKVFDLPFGS-------CLFRSDVYDNGSS-------FLYDNCTACTCRDSTV 266
Query: 297 ECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGE 346
CK+ C + C Q+ CC+ C + E++ F NK + GE
Sbjct: 267 VCKR-KCSHPGGCDQGQE---GCCEECLLRVPPEDIKVCKFGNKIFQDGE 312
Score = 47.8 bits (112), Expect = 2e-05
Identities = 47/206 (22%), Positives = 73/206 (35%), Gaps = 49/206 (23%)
Query: 141 NQCTQCSCSEGNVYCGLKTCPKLT--CAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQP 198
N C C C V C + CP L+ CA + +CC C+G ++ ++ P
Sbjct: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSP 124
Query: 199 ANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHG 258
A +P RQ G + +S G + N +H
Sbjct: 125 A-------------EPCVLRQC-----------QEGVVTES----GVRCVVHCKNPLEHL 156
Query: 259 QVC-------VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKY 311
+C V G Y GE + P +C C+C + +C + CP
Sbjct: 157 GMCCPTCPGCVFEGVQYQEGEEFQPEGS-----KCTKCSCTGGRTQCVREVCP---ILSC 208
Query: 312 PQKID----GKCCKVCPGKKAKEELP 333
PQ + G+CC C G++ +LP
Sbjct: 209 PQHLSHIPPGQCCPKCLGQRKVFDLP 234
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 76.6 bits (187), Expect = 4e-14
Identities = 54/196 (27%), Positives = 79/196 (40%), Gaps = 42/196 (21%)
Query: 2 RKKWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDK--KYRVGERWHPYLEPYGL 59
R++W++G + F T Q T C D ++ +G+ W P +P
Sbjct: 545 REEWRLGPGQCCF------------TCQEPTPSTGCSLDDNGVEFPIGQIWSPG-DP--- 588
Query: 60 VYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYN 119
C CIC +G+V C R C + C P+ IP CCP C S C Y
Sbjct: 589 --CELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDC-------------SAGCTYT 632
Query: 120 GTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 179
G + + E F + + C C C G+V C CP +TC +P CC VC
Sbjct: 633 GRIFYNNETFPSV-------LDPCLSCICLLGSVACSPVDCP-ITCTYPFHPDGECCPVC 684
Query: 180 RGDGELSWEHSDGDIF 195
R + ++G +F
Sbjct: 685 RDCNYEGRKVANGQVF 700
Score = 68.9 bits (167), Expect = 9e-12
Identities = 42/143 (29%), Positives = 60/143 (41%), Gaps = 29/143 (20%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C + + + E + L+P C++CIC G+V CS V CP + C P H CC
Sbjct: 629 CTYTGRIFYNNETFPSVLDP-----CLSCICLL-GSVACSPVDCP-ITCTYPFHPDGECC 681
Query: 97 PRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCG 156
P C + C Y G +G++F + CT+C+C G V C
Sbjct: 682 PVC--------------RDCNYEGRKVANGQVFTLDD-------EPCTRCTCQLGEVSCE 720
Query: 157 LKTCPKLTCAFPVSVPDSCCRVC 179
C + CA P +P CC C
Sbjct: 721 KVPCQR-ACADPALLPGDCCSSC 742
Score = 59.7 bits (143), Expect = 5e-09
Identities = 65/268 (24%), Positives = 96/268 (35%), Gaps = 50/268 (18%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHI--PHLCCPRCPEDSLPPVNNKVTSKSCEYN 119
C C+C +NG V CS + CP + C P CC C E + T S + N
Sbjct: 521 CTTCVC-QNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPT------PSTGCSLDDN 573
Query: 120 GTTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCPKLTCAFPVSVPDSCCRV 178
G + G+++ + C C C ++G+V C C +C P+ +P CC
Sbjct: 574 GVEFPIGQIW--------SPGDPCELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPD 624
Query: 179 CRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMD 238
C + G IF Y+ + PS LS L+
Sbjct: 625 CSAGCTYT-----GRIF-----------YNNETF---PSVLDPCLSCI--------CLLG 657
Query: 239 SQQASGTIVQIVINNK-HKHGQVC-VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQ 296
S S I H G+ C V Y + + + C CTC + +
Sbjct: 658 SVACSPVDCPITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEV 717
Query: 297 ECKKIHCPNRYPCKYPQKIDGKCCKVCP 324
C+K+ C + C P + G CC CP
Sbjct: 718 SCEKVPC--QRACADPALLPGDCCSSCP 743
Score = 58.5 bits (140), Expect = 1e-08
Identities = 65/271 (23%), Positives = 90/271 (33%), Gaps = 58/271 (21%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL---CCPRCPEDSLPPVNNKVTSKSCEY 118
C C C E+G V C +VRC C P IP CCP C C +
Sbjct: 404 CSQCWC-EDGKVTCEKVRC-EAACSHP--IPSRDGGCCPSCT--------------GCFH 445
Query: 119 NGTTYQHGELFVAEGLFQNRQPNQ-CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCR 177
+G G++F PN+ CT C C GNV C CP C P C
Sbjct: 446 SGVVRAEGDVF--------SPPNENCTVCVCLAGNVSCISPECPSGPCQTPPQTDCCTCV 497
Query: 178 VCRGDGELSWEHSDGDIFRQPANR----EARHSYHRSHYDPPPSRQAGGLSRFPGARSHR 233
R W ++DG +F + ++ + P P G
Sbjct: 498 PVRCYFHGRW-YADGAVFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCC 556
Query: 234 GALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV 293
+ ++G + NG + G+ W P C LC C
Sbjct: 557 FTCQEPTPSTGCSLD--------------DNGVEFPIGQIWSPG------DPCELCICQA 596
Query: 294 T-KQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
CK+ C + C +P +I G+CC C
Sbjct: 597 DGSVSCKRTDCVD--SCPHPIRIPGQCCPDC 625
Score = 42.7 bits (99), Expect = 7e-04
Identities = 50/203 (24%), Positives = 72/203 (35%), Gaps = 36/203 (17%)
Query: 143 CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS-CCRVCRGDGELSWEHSDGDIFRQPANR 201
C+QC C +G V C C + C+ P+ D CC C G ++GD+F P N
Sbjct: 404 CSQCWCEDGKVTCEKVRC-EAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVF-SPPNE 461
Query: 202 EARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVC 261
AG +S Q T V + C
Sbjct: 462 NCTVCVCL----------AGNVSCISPECPSGPCQTPPQTDCCTCVPVR----------C 501
Query: 262 VSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPN-RYPCKYPQKIDGKCC 320
+G+ Y+ G + + G EC C C + EC + CP P + + G+CC
Sbjct: 502 YFHGRWYADGAVF-----SGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCC 556
Query: 321 KVCPGKKAKEELP--GQSFDNKG 341
C +E P G S D+ G
Sbjct: 557 FTC-----QEPTPSTGCSLDDNG 574
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C ++ +K G+ + EP C C C + G V C +V C C P +P CC
Sbjct: 687 CNYEGRKVANGQVFTLDDEP-----CTRCTC-QLGEVSCEKVPCQRA-CADPALLPGDCC 739
Query: 97 PRCPEDSLPPVNNK 110
CP DSL P+ K
Sbjct: 740 SSCP-DSLSPLEEK 752
>gi|38348414 von Willebrand factor C domain containing 2 [Homo
sapiens]
Length = 325
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/139 (33%), Positives = 65/139 (46%), Gaps = 29/139 (20%)
Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIP-HLCCPRCPED 102
Y +GE++ P G C C+C+E G LC++ CP +H +H+ CCP+C E
Sbjct: 163 YAIGEKFAP-----GPSACP-CLCTEEGP-LCAQPECPRLHPRC-IHVDTSQCCPQCKE- 213
Query: 103 SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCP 161
CE+ G TYQ E FV + C +C C + G V C + CP
Sbjct: 214 ---------RKNYCEFRGKTYQTLEEFVV---------SPCERCRCEANGEVLCTVSACP 255
Query: 162 KLTCAFPVSVPDSCCRVCR 180
+ C PV PD CC +C+
Sbjct: 256 QTECVDPVYEPDQCCPICK 274
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 21/129 (16%)
Query: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P
Sbjct: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
Query: 89 VHIPHLCCPRC-------PEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPN 141
V+ P CCP C E ++ P +V + C TY+ EG ++ +
Sbjct: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-------EGTWRIERQA 315
Query: 142 QCTQCSCSE 150
CT+ C +
Sbjct: 316 MCTRHECRQ 324
>gi|30089980 chordin [Homo sapiens]
Length = 955
Score = 74.3 bits (181), Expect = 2e-13
Identities = 47/151 (31%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C F+ ++ G RW P +P C C C V+C V CP C PV P CC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759
Query: 97 PRCPED----SLPPV-NNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC--S 149
P CPE LP + ++ + C ++G + +C C+C
Sbjct: 760 PVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGG 819
Query: 150 EGNVYCGLKTCPKLTCAFPVSV-PDSCCRVC 179
G V+C CP+L CA PV V P CC+ C
Sbjct: 820 TGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
Score = 73.9 bits (180), Expect = 3e-13
Identities = 56/213 (26%), Positives = 75/213 (35%), Gaps = 68/213 (31%)
Query: 115 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS 174
+C + G HG + N P C+ C+C V C CP +C PV PD
Sbjct: 704 TCFFEGQQRPHGARWAP-----NYDP-LCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQ 757
Query: 175 CCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG 234
CC VC P ++ R P SR G F G RS R
Sbjct: 758 CCPVC------------------PEKQDVRDLPGL-----PRSRDPGEGCYFDGDRSWRA 794
Query: 235 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--N 292
A G WHP + FG+++C +CTC
Sbjct: 795 A-----------------------------------GTRWHPVVPPFGLIKCAVCTCKGG 819
Query: 293 VTKQECKKIHCPNRYPCKYPQKID-GKCCKVCP 324
+ C+K+ CP R C P +++ CCK CP
Sbjct: 820 TGEVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
Score = 60.1 bits (144), Expect = 4e-09
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 14/84 (16%)
Query: 261 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 307
C GK Y+ E+WHP+L FG++ CVLC C + CK I CP
Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109
Query: 308 PCKYPQKIDGKCCKVCPGKKAKEE 331
C P+++ G CC+ CP +++ E
Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSE 133
Score = 56.2 bits (134), Expect = 6e-08
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 12/78 (15%)
Query: 37 CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84
C F K Y + E WHP L EP+G++ CV C C G V C ++ CP
Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
Query: 85 CLSPVHIPHLCCPRCPED 102
C P +P CC CP++
Sbjct: 111 CGQPRQLPGHCCQTCPQE 128
Score = 52.4 bits (124), Expect = 9e-07
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320
C G+ HG W PN C LCTC C + CP C +P + +CC
Sbjct: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759
Query: 321 KVCPGKKAKEELPG 334
VCP K+ +LPG
Sbjct: 760 PVCPEKQDVRDLPG 773
Score = 36.2 bits (82), Expect = 0.064
Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95
C F + + + WHP + P+G + C+ C C G C R C + C S C
Sbjct: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928
Query: 96 CPRCPEDSLP 105
C RC P
Sbjct: 929 CSRCTAHRRP 938
Score = 34.7 bits (78), Expect = 0.19
Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 15/119 (12%)
Query: 116 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE----------GNVYC-GLKT-CPKL 163
C + G Y E + + L + +C C+C G V C +K CP
Sbjct: 51 CTFGGKVYALDETWHPD-LGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
Query: 164 TCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 222
C P +P CC+ C + S G F P R+ H + +P +A G
Sbjct: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 70.9 bits (172), Expect = 2e-12
Identities = 71/300 (23%), Positives = 103/300 (34%), Gaps = 55/300 (18%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP---VHIPH 93
C ++ ++ GE W L C C+C NG C +C + C V +P
Sbjct: 159 CSYEGHVFQDGEDWR-------LSRCAKCLC-RNGVAQCFTAQCQPLFCNQDETVVRVPG 210
Query: 94 LCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNV 153
CCP+C +++SC G Y+HGE + N CT C C G V
Sbjct: 211 KCCPQC------------SARSCSAAGQVYEHGEQW---------SENACTTCICDRGEV 249
Query: 154 YCGLKTCPKLTCAFPVSVP---DSCCRVCRGD-GELSWEHSDGDIFRQPANREARHSYHR 209
C + C L C S CC C G S+ DG + Q +
Sbjct: 250 RCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSY---DGVVRYQDEMWKGSACEFC 306
Query: 210 SHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNKHKHGQVCVSNG---K 266
+ Q G ++ AR +D + I + + G+ SN K
Sbjct: 307 MCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVK 366
Query: 267 TYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPC---KYPQKIDGKCCKVC 323
GE W C +C C + C + CP PC ++ G+CC C
Sbjct: 367 RIPEGEKWEDG-------PCKVCECRGAQVTCYEPSCP---PCPVGTLALEVKGQCCPDC 416
Score = 68.6 bits (166), Expect = 1e-11
Identities = 77/313 (24%), Positives = 111/313 (35%), Gaps = 78/313 (24%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVH- 90
HSE C++QD W P C +C C V+C C N C
Sbjct: 23 HSEGACVYQDSLLADATIWKPDS-------CQSCRC-HGDIVICKPAVCRNPQCAFEKGE 74
Query: 91 ----IPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQC 146
+ CCP C T SC + ++HG + + + C+ C
Sbjct: 75 VLQIAANQCCPECVLR---------TPGSCHHEKKIHEHGTEWAS---------SPCSVC 116
Query: 147 SCSEGNVYCGLKTCPKLTCAFP--VSVPD-SCCRVCRGDGE-LSWE---HSDGDIFR--- 196
SC+ G V C + CP L+C +P+ SCC VC G G+ S+E DG+ +R
Sbjct: 117 SCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSR 176
Query: 197 --QPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGALMDSQQASGTIVQIVINNK 254
+ R + P Q + R PG + +
Sbjct: 177 CAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCS------------------- 217
Query: 255 HKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHC-PNRYPCKYPQ 313
+ C + G+ Y HGE W N C C C+ + C K C P R C Q
Sbjct: 218 ---ARSCSAAGQVYEHGEQWSEN-------ACTTCICDRGEVRCHKQACLPLR--CGKGQ 265
Query: 314 ---KIDGKCCKVC 323
+ G+CC+ C
Sbjct: 266 SRARRHGQCCEEC 278
Score = 34.3 bits (77), Expect = 0.24
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 15/70 (21%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNV-----TKQECKKIHCPNRYPCKYPQKI 315
C K + HG W + C +C+CN T Q C + C ++ P
Sbjct: 95 CHHEKKIHEHGTEWASS-------PCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIP--- 144
Query: 316 DGKCCKVCPG 325
+G CC VC G
Sbjct: 145 EGSCCPVCVG 154
>gi|122937446 von Willebrand factor C domain-containing protein
2-like [Homo sapiens]
Length = 222
Score = 68.6 bits (166), Expect = 1e-11
Identities = 45/140 (32%), Positives = 62/140 (44%), Gaps = 31/140 (22%)
Query: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPE 101
Y++GER+ P G C C+C+ +G V C + CP +H C H + CCP C E
Sbjct: 61 YKLGERFFP-----GHSNCP-CVCALDGPV-CDQPECPKIHPKCTKVEH--NGCCPECKE 111
Query: 102 DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN-VYCGLKTC 160
CEY+G Y+ E F +P+ C C C N V+C + C
Sbjct: 112 ----------VKNFCEYHGKNYKILEEF---------KPSPCEWCRCEPSNEVHCVVADC 152
Query: 161 PKLTCAFPVSVPDSCCRVCR 180
C PV P+ CC VC+
Sbjct: 153 AVPECVNPVYEPEQCCPVCK 172
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/140 (22%), Positives = 50/140 (35%), Gaps = 31/140 (22%)
Query: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84
G + K + +C + K Y++ E + P P C C C + V C C
Sbjct: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156
Query: 85 CLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCT 144
C++PV+ P CCP C NG G + G+ + ++C
Sbjct: 157 CVNPVYEPEQCCPVCK------------------NGPNCFAGTTIIPAGI--EVKVDECN 196
Query: 145 QCSCSEGN----VYCGLKTC 160
C C G+ C + C
Sbjct: 197 ICHCHNGDWWKPAQCSKREC 216
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 60.1 bits (144), Expect = 4e-09
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG- 120
C C C + G + C R C C +P CCP C + +VTS+ + NG
Sbjct: 607 CSVCSCKD-GKIFCRRTACD---CQNP-SADLFCCPEC--------DTRVTSQCLDQNGH 653
Query: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
Y+ G+ + + C QC C EG V C TCP L+C + + CC C
Sbjct: 654 KLYRSGDNWT----------HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCV 703
Query: 181 GD 182
D
Sbjct: 704 SD 705
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 43/187 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88
H E C YR + W +C NC C ++G V C R+ CP ++C P
Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC 148
VHI CC KV C Y G G+ + + C +C
Sbjct: 321 VHIAGQCC-------------KVCRPKCIYGGKVLAEGQRILTKS---------CREC-- 356
Query: 149 SEGNVYCGL-KTCPKLTCAFPVSV--PDSCCRVCRG-----DGELSWEHSDGDIFRQPAN 200
G V + + CP L C+ + + CCRVCRG +G E+S+ + A
Sbjct: 357 -RGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKAT 415
Query: 201 REARHSY 207
E + Y
Sbjct: 416 CECKSGY 422
Score = 51.6 bits (122), Expect = 1e-06
Identities = 38/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Query: 37 CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ K YR G+ W C C C E G V C + CPN+ C +
Sbjct: 647 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 697
Query: 95 CCPRCPEDSLPPVNNKVT---SKSC-EYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE 150
CCPRC D P + + +T K+C + G + G ++ G + CT C C
Sbjct: 698 CCPRCVSD--PCLADNITYDIRKTCLDSYGVSRLSGSVWTMAG-------SPCTTCKCKN 748
Query: 151 GNVYCGL 157
G V C +
Sbjct: 749 GRVCCSV 755
Score = 50.1 bits (118), Expect = 4e-06
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Query: 101 EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTC 160
E L + N K+C+ +G Y+ + +V + C C+C G V C +C
Sbjct: 258 ETRLSQLENCHCEKTCQVSGLLYRDQDSWV--------DGDHCRNCTCKSGAVECRRMSC 309
Query: 161 PKLTC---AFPVSVPDSCCRVCR 180
P L C + PV + CC+VCR
Sbjct: 310 PPLNCSPDSLPVHIAGQCCKVCR 332
Score = 43.1 bits (100), Expect = 5e-04
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 316
+ C +G Y +SW C CTC EC+++ CP N P P I
Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324
Query: 317 GKCCKVCPGK 326
G+CCKVC K
Sbjct: 325 GQCCKVCRPK 334
Score = 36.2 bits (82), Expect = 0.064
Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 266 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
K Y G++W + C C C + +C + CPN C+Y ++G+CC C
Sbjct: 654 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 702
Score = 31.2 bits (69), Expect = 2.0
Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Query: 113 SKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP 172
S C + G +G+++ + ++C+ CSC +G ++C C C P S
Sbjct: 584 SGDCPHEGGLKHNGQVWTLK-------EDRCSVCSCKDGKIFCRRTAC---DCQNP-SAD 632
Query: 173 DSCCRVC 179
CC C
Sbjct: 633 LFCCPEC 639
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 60.1 bits (144), Expect = 4e-09
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNG- 120
C C C + G + C R C C +P CCP C + +VTS+ + NG
Sbjct: 654 CSVCSCKD-GKIFCRRTACD---CQNP-SADLFCCPEC--------DTRVTSQCLDQNGH 700
Query: 121 TTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
Y+ G+ + + C QC C EG V C TCP L+C + + CC C
Sbjct: 701 KLYRSGDNWT----------HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCV 750
Query: 181 GD 182
D
Sbjct: 751 SD 752
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 43/187 (22%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLS---P 88
H E C YR + W +C NC C ++G V C R+ CP ++C P
Sbjct: 268 HCEKTCQVSGLLYRDQDSW------VDGDHCRNCTC-KSGAVECRRMSCPPLNCSPDSLP 320
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC 148
VHI CC KV C Y G G+ + + C +C
Sbjct: 321 VHIAGQCC-------------KVCRPKCIYGGKVLAEGQRILTKS---------CREC-- 356
Query: 149 SEGNVYCGL-KTCPKLTCAFPVSV--PDSCCRVCRG-----DGELSWEHSDGDIFRQPAN 200
G V + + CP L C+ + + CCRVCRG +G E+S+ + A
Sbjct: 357 -RGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKAT 415
Query: 201 REARHSY 207
E + Y
Sbjct: 416 CECKSGY 422
Score = 51.6 bits (122), Expect = 1e-06
Identities = 38/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Query: 37 CMFQD--KKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ K YR G+ W C C C E G V C + CPN+ C +
Sbjct: 694 CLDQNGHKLYRSGDNWTHS--------CQQCRCLE-GEVDCWPLTCPNLSCEYTAILEGE 744
Query: 95 CCPRCPEDSLPPVNNKVT---SKSC-EYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE 150
CCPRC D P + + +T K+C + G + G ++ G + CT C C
Sbjct: 745 CCPRCVSD--PCLADNITYDIRKTCLDSYGVSRLSGSVWTMAG-------SPCTTCKCKN 795
Query: 151 GNVYCGL 157
G V C +
Sbjct: 796 GRVCCSV 802
Score = 50.1 bits (118), Expect = 4e-06
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Query: 101 EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTC 160
E L + N K+C+ +G Y+ + +V + C C+C G V C +C
Sbjct: 258 ETRLSQLENCHCEKTCQVSGLLYRDQDSWV--------DGDHCRNCTCKSGAVECRRMSC 309
Query: 161 PKLTC---AFPVSVPDSCCRVCR 180
P L C + PV + CC+VCR
Sbjct: 310 PPLNCSPDSLPVHIAGQCCKVCR 332
Score = 43.1 bits (100), Expect = 5e-04
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 8/70 (11%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCP--NRYPCKYPQKID 316
+ C +G Y +SW C CTC EC+++ CP N P P I
Sbjct: 271 KTCQVSGLLYRDQDSWVDG------DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIA 324
Query: 317 GKCCKVCPGK 326
G+CCKVC K
Sbjct: 325 GQCCKVCRPK 334
Score = 36.2 bits (82), Expect = 0.064
Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 266 KTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVC 323
K Y G++W + C C C + +C + CPN C+Y ++G+CC C
Sbjct: 701 KLYRSGDNWTHS--------CQQCRCLEGEVDCWPLTCPN-LSCEYTAILEGECCPRC 749
Score = 31.2 bits (69), Expect = 2.0
Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Query: 113 SKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP 172
S C + G +G+++ + ++C+ CSC +G ++C C C P S
Sbjct: 631 SGDCPHEGGLKHNGQVWTLK-------EDRCSVCSCKDGKIFCRRTAC---DCQNP-SAD 679
Query: 173 DSCCRVC 179
CC C
Sbjct: 680 LFCCPEC 686
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG
Sbjct: 683 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC--------DPRLSSQCLHQNGE 729
Query: 122 T-YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
T Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 730 TLYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCV 779
Query: 181 GD 182
D
Sbjct: 780 TD 781
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 39/168 (23%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 292 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 342
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQ 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 343 AYVDGKCCKEC-------------KSICQFQGRTYFEGERNTVYSSSGV--------CVL 381
Query: 146 CSCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 190
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 382 YECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 429
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 723 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 773
Query: 95 CCPRCPED--SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 152
CCPRC D + N +T + G ++ G +CT C C G+
Sbjct: 774 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 826
Query: 153 VYCGL 157
+ C +
Sbjct: 827 ICCSV 831
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 316
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 295 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 346
Query: 317 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 354
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 347 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 394
Score = 34.3 bits (77), Expect = 0.24
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 22/98 (22%)
Query: 98 RCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 652 RCP-------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRR 697
Query: 158 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 193
C C P +V CC C D LS + H +G+
Sbjct: 698 MVC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 729
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 260 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 313
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 356 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 409
Query: 314 KIDGKCCKVCPG 325
+ CCKVC G
Sbjct: 410 -LSHSCCKVCKG 420
Score = 30.8 bits (68), Expect = 2.7
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 18/155 (11%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 351 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 407
Query: 89 VHIPHLCCPRCP-EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 145
+ + H CC C D +N + + C +G R+ N +
Sbjct: 408 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 464
Query: 146 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
C+EG YC T V+ P S +C+
Sbjct: 465 DECAEGRHYCRENT-------MCVNTPGSFMCICK 492
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG
Sbjct: 659 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC--------DPRLSSQCLHQNGE 705
Query: 122 T-YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
T Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 706 TLYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCV 755
Query: 181 GD 182
D
Sbjct: 756 TD 757
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 39/168 (23%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 268 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 318
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQ 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 319 AYVDGKCCKEC-------------KSICQFQGRTYFEGERNTVYSSSGV--------CVL 357
Query: 146 CSCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 190
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 358 YECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 405
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 699 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 749
Query: 95 CCPRCPED--SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 152
CCPRC D + N +T + G ++ G +CT C C G+
Sbjct: 750 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 802
Query: 153 VYCGL 157
+ C +
Sbjct: 803 ICCSV 807
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 316
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 271 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 322
Query: 317 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 354
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 323 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 370
Score = 34.3 bits (77), Expect = 0.24
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 22/98 (22%)
Query: 98 RCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 628 RCP-------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRR 673
Query: 158 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 193
C C P +V CC C D LS + H +G+
Sbjct: 674 MVC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 705
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 260 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 313
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 332 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 385
Query: 314 KIDGKCCKVCPG 325
+ CCKVC G
Sbjct: 386 -LSHSCCKVCKG 396
Score = 30.8 bits (68), Expect = 2.7
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 18/155 (11%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 327 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 383
Query: 89 VHIPHLCCPRCP-EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 145
+ + H CC C D +N + + C +G R+ N +
Sbjct: 384 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 440
Query: 146 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
C+EG YC T V+ P S +C+
Sbjct: 441 DECAEGRHYCRENT-------MCVNTPGSFMCICK 468
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG
Sbjct: 660 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC--------DPRLSSQCLHQNGE 706
Query: 122 T-YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
T Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 707 TLYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCV 756
Query: 181 GD 182
D
Sbjct: 757 TD 758
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 39/168 (23%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQ 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 320 AYVDGKCCKEC-------------KSICQFQGRTYFEGERNTVYSSSGV--------CVL 358
Query: 146 CSCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 190
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 359 YECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 406
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750
Query: 95 CCPRCPED--SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 152
CCPRC D + N +T + G ++ G +CT C C G+
Sbjct: 751 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 803
Query: 153 VYCGL 157
+ C +
Sbjct: 804 ICCSV 808
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 316
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323
Query: 317 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 354
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 324 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371
Score = 34.3 bits (77), Expect = 0.24
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 22/98 (22%)
Query: 98 RCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 629 RCP-------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRR 674
Query: 158 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 193
C C P +V CC C D LS + H +G+
Sbjct: 675 MVC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 706
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 260 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 313
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386
Query: 314 KIDGKCCKVCPG 325
+ CCKVC G
Sbjct: 387 -LSHSCCKVCKG 397
Score = 30.8 bits (68), Expect = 2.7
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 18/155 (11%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384
Query: 89 VHIPHLCCPRCP-EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 145
+ + H CC C D +N + + C +G R+ N +
Sbjct: 385 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 441
Query: 146 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
C+EG YC T V+ P S +C+
Sbjct: 442 DECAEGRHYCRENT-------MCVNTPGSFMCICK 469
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG
Sbjct: 710 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC--------DPRLSSQCLHQNGE 756
Query: 122 T-YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
T Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 757 TLYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCV 806
Query: 181 GD 182
D
Sbjct: 807 TD 808
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 39/168 (23%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 319 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 369
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQ 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 370 AYVDGKCCKEC-------------KSICQFQGRTYFEGERNTVYSSSGV--------CVL 408
Query: 146 CSCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 190
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 409 YECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 456
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 750 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 800
Query: 95 CCPRCPED--SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 152
CCPRC D + N +T + G ++ G +CT C C G+
Sbjct: 801 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 853
Query: 153 VYCGL 157
+ C +
Sbjct: 854 ICCSV 858
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 316
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 322 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 373
Query: 317 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 354
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 374 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 421
Score = 34.3 bits (77), Expect = 0.24
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 22/98 (22%)
Query: 98 RCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 679 RCP-------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRR 724
Query: 158 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 193
C C P +V CC C D LS + H +G+
Sbjct: 725 MVC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 756
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 260 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 313
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 383 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 436
Query: 314 KIDGKCCKVCPG 325
+ CCKVC G
Sbjct: 437 -LSHSCCKVCKG 447
Score = 30.8 bits (68), Expect = 2.7
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 18/155 (11%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 378 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 434
Query: 89 VHIPHLCCPRCP-EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 145
+ + H CC C D +N + + C +G R+ N +
Sbjct: 435 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 491
Query: 146 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
C+EG YC T V+ P S +C+
Sbjct: 492 DECAEGRHYCRENT-------MCVNTPGSFMCICK 519
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 24/122 (19%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGT 121
C C C +NG V+C R+ C C +P + CCP C + +++S+ NG
Sbjct: 660 CSVCSC-QNGFVMCRRMVCD---CENPT-VDLFCCPEC--------DPRLSSQCLHQNGE 706
Query: 122 T-YQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
T Y G+ +V C QC C +G V C CP + C F + + CC C
Sbjct: 707 TLYNSGDTWV----------QNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCV 756
Query: 181 GD 182
D
Sbjct: 757 TD 758
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 39/168 (23%)
Query: 32 HSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC---LSP 88
+ E C + YR E W + C NC C NG + C + CPN C +
Sbjct: 269 YCERTCTMKGTTYREFESW--------IDGCKNCTCL-NGTIQCETLICPNPDCPLKSAL 319
Query: 89 VHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGE---LFVAEGLFQNRQPNQCTQ 145
++ CC C C++ G TY GE ++ + G+ C
Sbjct: 320 AYVDGKCCKEC-------------KSICQFQGRTYFEGERNTVYSSSGV--------CVL 358
Query: 146 CSCSEGNVYCGLKT-CPKLTC--AFPVSVPDSCCRVCRGDGELSWEHS 190
C + + + CP L C + +++ SCC+VC+G S H+
Sbjct: 359 YECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHN 406
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 37 CMFQDKK--YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHL 94
C+ Q+ + Y G+ W + C C C + G V C + CP+V C + +
Sbjct: 700 CLHQNGETLYNSGDTW--------VQNCQQCRCLQ-GEVDCWPLPCPDVECEFSILPENE 750
Query: 95 CCPRCPED--SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN 152
CCPRC D + N +T + G ++ G +CT C C G+
Sbjct: 751 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHG-------TECTLCQCKNGH 803
Query: 153 VYCGL 157
+ C +
Sbjct: 804 ICCSV 808
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 20/108 (18%)
Query: 259 QVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR-YPCKYPQK-ID 316
+ C G TY ESW I C CTC +C+ + CPN P K +D
Sbjct: 272 RTCTMKGTTYREFESW--------IDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVD 323
Query: 317 GKCCKVC------PGKKAKEELPGQSFDNKG----YFCGEETMPVYES 354
GKCCK C G+ E + + G Y C ++TM + ES
Sbjct: 324 GKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVES 371
Score = 34.3 bits (77), Expect = 0.24
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 22/98 (22%)
Query: 98 RCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGL 157
RCP + K + C ++G +G+++V E ++C+ CSC G V C
Sbjct: 629 RCP-------HGKNCTGDCIHDGKVKHNGQIWVLEN-------DRCSVCSCQNGFVMCRR 674
Query: 158 KTCPKLTCAFPVSVPDSCCRVCRGDGELSWE--HSDGD 193
C C P +V CC C D LS + H +G+
Sbjct: 675 MVC---DCENP-TVDLFCCPEC--DPRLSSQCLHQNGE 706
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 260 VCVSNGKTYSHGESWHPNLRAFGIVECVLCTCN------VTKQECKKIHCPNRYPCKYPQ 313
+C G+TY GE + + G+ CVL C V C + CP +
Sbjct: 333 ICQFQGRTYFEGER-NTVYSSSGV--CVLYECKDQTMKLVESSGCPALDCPESHQIT--- 386
Query: 314 KIDGKCCKVCPG 325
+ CCKVC G
Sbjct: 387 -LSHSCCKVCKG 397
Score = 30.8 bits (68), Expect = 2.7
Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 18/155 (11%)
Query: 31 KHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHC--LSP 88
K ++ C FQ + Y GER Y CV C + L CP + C
Sbjct: 328 KECKSICQFQGRTYFEGERNTVYSSS---GVCVLYECKDQTMKLVESSGCPALDCPESHQ 384
Query: 89 VHIPHLCCPRCP-EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ-- 145
+ + H CC C D +N + + C +G R+ N +
Sbjct: 385 ITLSHSCCKVCKGYDFCSERHNCMENSICR---NLNDRAVCSCRDGFRALREDNAYCEDI 441
Query: 146 CSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCR 180
C+EG YC T V+ P S +C+
Sbjct: 442 DECAEGRHYCRENT-------MCVNTPGSFMCICK 469
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 54.3 bits (129), Expect = 2e-07
Identities = 19/37 (51%), Positives = 25/37 (67%)
Query: 143 CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 179
CT C C +G V C ++ CP TCA PV++P +CC VC
Sbjct: 1434 CTICECKDGQVTCFVEACPPATCAVPVNIPGACCPVC 1470
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99
C C C + G V C CP C PV+IP CCP C
Sbjct: 1434 CTICECKD-GQVTCFVEACPPATCAVPVNIPGACCPVC 1470
Score = 38.1 bits (87), Expect = 0.017
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320
CV G GES H N + C +C C + C CP C P I G CC
Sbjct: 1415 CVDAG-----GES-HANNTKWKKDACTICECKDGQVTCFVEACPPA-TCAVPVNIPGACC 1467
Query: 321 KVCPGKKAKEE 331
VC K+A+E+
Sbjct: 1468 PVCLQKRAEEK 1478
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 45.8 bits (107), Expect = 8e-05
Identities = 18/41 (43%), Positives = 21/41 (51%)
Query: 143 CTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDG 183
CT C C G V C ++ CP C P V +CC VCR G
Sbjct: 1414 CTHCICESGQVTCVVEICPPAPCPSPELVKGTCCPVCRDRG 1454
Score = 41.2 bits (95), Expect = 0.002
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLP 105
C +CIC E+G V C CP C SP + CCP C + +P
Sbjct: 1414 CTHCIC-ESGQVTCVVEICPPAPCPSPELVKGTCCPVCRDRGMP 1456
Score = 34.7 bits (78), Expect = 0.19
Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 1/49 (2%)
Query: 285 ECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELP 333
+C C C + C CP PC P+ + G CC VC + + P
Sbjct: 1413 DCTHCICESGQVTCVVEICPPA-PCPSPELVKGTCCPVCRDRGMPSDSP 1460
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 13/85 (15%)
Query: 105 PPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLT 164
PP +++ C +G + E +V + CT C+C + C TCP T
Sbjct: 311 PPKTRNMSA--CWQDGRFFAENETWVVDS---------CTTCTCKKFKTICHQITCPPAT 359
Query: 165 CAFPVSVPDSCCRVC--RGDGELSW 187
CA P V CC C DGE W
Sbjct: 360 CASPSFVEGECCPSCLHSVDGEEGW 384
Score = 43.5 bits (101), Expect = 4e-04
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 254 KHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQ 313
K ++ C +G+ ++ E+W + C CTC K C +I CP C P
Sbjct: 313 KTRNMSACWQDGRFFAENETWV-------VDSCTTCTCKKFKTICHQITCPPA-TCASPS 364
Query: 314 KIDGKCCKVC 323
++G+CC C
Sbjct: 365 FVEGECCPSC 374
Score = 36.6 bits (83), Expect = 0.049
Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 1/38 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99
C C C + +C ++ CP C SP + CCP C
Sbjct: 338 CTTCTCKKF-KTICHQITCPPATCASPSFVEGECCPSC 374
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/169 (23%), Positives = 74/169 (43%), Gaps = 27/169 (15%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKI--DGK 318
C+ G T + W P C C C+ + C + C +P + PQ + +G+
Sbjct: 103 CLVKGITMYNKAVWSPE-------PCTTCLCSDGRVLCDETMC---HPQRCPQTVIPEGE 152
Query: 319 CCKVCPGKKAKEELPGQSFDNKGYFCGEETMPVYESVFMEDGETTRKIALETERPPQVEV 378
CC VC + L G + +++ F G+ + E E T + + PPQV +
Sbjct: 153 CCPVCSATVSYSLLSGIALNDRNEFSGDSS---------EQREPTNLLHKQLP-PPQVGM 202
Query: 379 HVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEGEAQ 427
+RK LQ E++ + E+ K T + +Q ++++EG+++
Sbjct: 203 D-RIVRKEALQSEEDEEVKEEDTEQ----KRETPESRNQGQLYSEGDSR 246
Score = 38.1 bits (87), Expect = 0.017
Identities = 16/40 (40%), Positives = 17/40 (42%)
Query: 140 PNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVC 179
P CT C CS+G V C C C V CC VC
Sbjct: 118 PEPCTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVC 157
Score = 33.9 bits (76), Expect = 0.32
Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 62 CVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC 99
C C+CS+ G VLC C C V CCP C
Sbjct: 121 CTTCLCSD-GRVLCDETMCHPQRCPQTVIPEGECCPVC 157
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320
CV NG Y + W P C +C C+ K C + C C + +G+CC
Sbjct: 40 CVQNGLRYHDRDVWKPE-------PCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECC 92
Query: 321 KVCP 324
VCP
Sbjct: 93 PVCP 96
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPH-LC 95
C+ +Y + W P EP C C+C +NG VLC V C +P C
Sbjct: 40 CVQNGLRYHDRDVWKP--EP-----CRICVC-DNGKVLCDDVICDETKNCPGAEVPEGEC 91
Query: 96 CPRCPEDSLPPVNNKVT 112
CP CP+ S P + + T
Sbjct: 92 CPVCPDGSESPTDQETT 108
Score = 34.3 bits (77), Expect = 0.24
Identities = 21/85 (24%), Positives = 32/85 (37%), Gaps = 17/85 (20%)
Query: 101 EDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTC 160
++ +PP+ +C NG Y +++ +P C C C G V C C
Sbjct: 32 DEDIPPI-------TCVQNGLRYHDRDVW---------KPEPCRICVCDNGKVLCDDVIC 75
Query: 161 PKLTCAFPVSVPD-SCCRVCRGDGE 184
+ VP+ CC VC E
Sbjct: 76 DETKNCPGAEVPEGECCPVCPDGSE 100
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 43.9 bits (102), Expect = 3e-04
Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 17/91 (18%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320
CV +G+ Y+ + W P C +C C+ C I C + C P+ G+CC
Sbjct: 34 CVQDGQRYNDKDVWKPE-------PCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECC 86
Query: 321 KVC----------PGKKAKEELPGQSFDNKG 341
+C PG K ++ PG D G
Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVG 117
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 9/67 (13%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH-CLSPVHIPHLC 95
C+ ++Y + W P EP C C+C + G VLC + C +V CLSP C
Sbjct: 34 CVQDGQRYNDKDVWKP--EP-----CRICVC-DTGTVLCDDIICEDVKDCLSPEIPFGEC 85
Query: 96 CPRCPED 102
CP CP D
Sbjct: 86 CPICPTD 92
Score = 30.4 bits (67), Expect = 3.5
Identities = 17/69 (24%), Positives = 25/69 (36%), Gaps = 10/69 (14%)
Query: 115 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVP-D 173
SC +G Y +++ +P C C C G V C C + +P
Sbjct: 33 SCVQDGQRYNDKDVW---------KPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFG 83
Query: 174 SCCRVCRGD 182
CC +C D
Sbjct: 84 ECCPICPTD 92
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 7/63 (11%)
Query: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320
C NG+ Y + + W P C +C C+ C KI C + C P G+CC
Sbjct: 41 CTQNGQMYLNRDIWKP-------APCQICVCDNGAILCDKIECQDVLDCADPVTPPGECC 93
Query: 321 KVC 323
VC
Sbjct: 94 PVC 96
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 9/69 (13%)
Query: 34 ETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNV-HCLSPVHIP 92
E C + Y + W P C C+C +NG +LC ++ C +V C PV P
Sbjct: 38 EIACTQNGQMYLNRDIWKP-------APCQICVC-DNGAILCDKIECQDVLDCADPVTPP 89
Query: 93 HLCCPRCPE 101
CCP C +
Sbjct: 90 GECCPVCSQ 98
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)
Query: 115 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK-LTCAFPVSVPD 173
+C NG Y + +++ +P C C C G + C C L CA PV+ P
Sbjct: 40 ACTQNGQMYLNRDIW---------KPAPCQICVCDNGAILCDKIECQDVLDCADPVTPPG 90
Query: 174 SCCRVC 179
CC VC
Sbjct: 91 ECCPVC 96
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 43.5 bits (101), Expect = 4e-04
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 8/71 (11%)
Query: 253 NKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYP 312
N+ + +C NG Y + E W + C C C + CKK+ CP PC
Sbjct: 310 NELRRPPLCYHNGVQYRNNEEWT-------VDSCTECHCQNSVTICKKVSCP-IMPCSNA 361
Query: 313 QKIDGKCCKVC 323
DG+CC C
Sbjct: 362 TVPDGECCPRC 372
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 9/68 (13%)
Query: 37 CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96
C +YR E W + C C C +N +C +V CP + C + CC
Sbjct: 318 CYHNGVQYRNNEEWT-------VDSCTECHC-QNSVTICKKVSCPIMPCSNATVPDGECC 369
Query: 97 PRC-PEDS 103
PRC P DS
Sbjct: 370 PRCWPSDS 377
Score = 37.4 bits (85), Expect = 0.029
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 11/65 (16%)
Query: 116 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPD-S 174
C +NG Y++ E + + CT+C C C +CP + C+ +VPD
Sbjct: 318 CYHNGVQYRNNEEWTVDS---------CTECHCQNSVTICKKVSCPIMPCS-NATVPDGE 367
Query: 175 CCRVC 179
CC C
Sbjct: 368 CCPRC 372
>gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
Length = 381
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%)
Query: 114 KSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPK------LTCAF 167
+ CEYN YQ+GE F QPN QC+C +G V C + CP+ L C
Sbjct: 98 RPCEYNSRIYQNGESF---------QPNCKHQCTCIDGAVGC-IPLCPQELSLPNLGCPN 147
Query: 168 P--VSVPDSCCR--VCRGD 182
P V V CC VC D
Sbjct: 148 PRLVKVTGQCCEEWVCDED 166
Score = 33.9 bits (76), Expect = 0.32
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 17/87 (19%)
Query: 258 GQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQEC-----KKIHCPNRYPCKYP 312
G+ C N + Y +GES+ PN + CTC C +++ PN C P
Sbjct: 97 GRPCEYNSRIYQNGESFQPNCKH-------QCTCIDGAVGCIPLCPQELSLPN-LGCPNP 148
Query: 313 Q--KIDGKCCK--VCPGKKAKEELPGQ 335
+ K+ G+CC+ VC K+ + Q
Sbjct: 149 RLVKVTGQCCEEWVCDEDSIKDPMEDQ 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,684,336
Number of Sequences: 37866
Number of extensions: 1119177
Number of successful extensions: 3603
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 2948
Number of HSP's gapped (non-prelim): 542
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.