Search of human proteins with 221136834

Search of human proteins with 221136834

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221136834 transducin-like enhancer of split 6 isoform 1
[Homo sapiens]
         (572 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo...  1188   0.0  
gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo ...   940   0.0  
gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ...   218   2e-56
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s...   218   2e-56
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]         203   3e-52
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ...   199   7e-51
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ...   199   7e-51
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ...   199   7e-51
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]         198   1e-50
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ...   162   6e-40
gi|83779014 katanin p80 subunit B 1 [Homo sapiens]                     52   2e-06
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom...    47   5e-05
gi|13376840 WD repeat domain 61 [Homo sapiens]                         47   5e-05
gi|62234438 Notchless gene homolog isoform b [Homo sapiens]            45   1e-04
gi|62234461 Notchless gene homolog isoform a [Homo sapiens]            45   1e-04
gi|8922301 WD repeat domain 70 [Homo sapiens]                          45   2e-04
gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]            43   7e-04
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]    43   7e-04
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]     42   0.002
gi|18874090 WD repeat domain 48 [Homo sapiens]                         40   0.008
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi...    40   0.008
gi|157266266 WD repeat domain 86 [Homo sapiens]                        40   0.008
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     39   0.010
gi|26665869 WD repeat domain 51B [Homo sapiens]                        39   0.010
gi|21281677 WD repeat domain 36 [Homo sapiens]                         39   0.013
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H...    39   0.017
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    39   0.017
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H...    39   0.017
gi|38569484 kinesin family member 21A [Homo sapiens]                   38   0.022
gi|41281564 WD repeat domain 37 [Homo sapiens]                         37   0.037

>gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo
           sapiens]
          Length = 572

 Score = 1188 bits (3073), Expect = 0.0
 Identities = 572/572 (100%), Positives = 572/572 (100%)

Query: 1   MTSRDQPRPKGPPKSTSPCPGISNSESSPTLNYQGILNRLKQFPRFSPHFAAELESIYYS 60
           MTSRDQPRPKGPPKSTSPCPGISNSESSPTLNYQGILNRLKQFPRFSPHFAAELESIYYS
Sbjct: 1   MTSRDQPRPKGPPKSTSPCPGISNSESSPTLNYQGILNRLKQFPRFSPHFAAELESIYYS 60

Query: 61  LHKIQQDVAEHHKQIGNVLQIVESCSQLQGFQSEEVSPAEPASPGTPQQVKDKTLQESSF 120
           LHKIQQDVAEHHKQIGNVLQIVESCSQLQGFQSEEVSPAEPASPGTPQQVKDKTLQESSF
Sbjct: 61  LHKIQQDVAEHHKQIGNVLQIVESCSQLQGFQSEEVSPAEPASPGTPQQVKDKTLQESSF 120

Query: 121 EDIMATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDR 180
           EDIMATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDR
Sbjct: 121 EDIMATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDR 180

Query: 181 QQAPGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRA 240
           QQAPGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRA
Sbjct: 181 QQAPGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRA 240

Query: 241 SRFLQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRH 300
           SRFLQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRH
Sbjct: 241 SRFLQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRH 300

Query: 301 VFTCGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVS 360
           VFTCGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVS
Sbjct: 301 VFTCGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVS 360

Query: 361 VWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGY 420
           VWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGY
Sbjct: 361 VWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGY 420

Query: 421 PDGVKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMA 480
           PDGVKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMA
Sbjct: 421 PDGVKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMA 480

Query: 481 NGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVP 540
           NGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVP
Sbjct: 481 NGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVP 540

Query: 541 EMSPVTCCDVSSNNRLVVTGSGEHASVYQITY 572
           EMSPVTCCDVSSNNRLVVTGSGEHASVYQITY
Sbjct: 541 EMSPVTCCDVSSNNRLVVTGSGEHASVYQITY 572


>gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo
           sapiens]
          Length = 449

 Score =  940 bits (2429), Expect = 0.0
 Identities = 449/449 (100%), Positives = 449/449 (100%)

Query: 124 MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA 183
           MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA
Sbjct: 1   MATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAGVHDEKAKPRDRQQA 60

Query: 184 PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF 243
           PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF
Sbjct: 61  PGLGQESKAPGSCDPGTDPCPEDASTPRPPEASSSPPEGSQDRNTSWGVVQEPPGRASRF 120

Query: 244 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT 303
           LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT
Sbjct: 121 LQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFT 180

Query: 304 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD 363
           CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD
Sbjct: 181 CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD 240

Query: 364 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG 423
           LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG
Sbjct: 241 LAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDG 300

Query: 424 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ 483
           VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ
Sbjct: 301 VKSIVVKGYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQ 360

Query: 484 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS 543
           QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS
Sbjct: 361 QWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMS 420

Query: 544 PVTCCDVSSNNRLVVTGSGEHASVYQITY 572
           PVTCCDVSSNNRLVVTGSGEHASVYQITY
Sbjct: 421 PVTCCDVSSNNRLVVTGSGEHASVYQITY 449


>gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo
           sapiens]
          Length = 621

 Score =  218 bits (554), Expect = 2e-56
 Identities = 114/314 (36%), Positives = 182/314 (57%), Gaps = 10/314 (3%)

Query: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
           DAL G      +P    ++  LAHGE+V A  IS  T+HV+T G+  +KVW + GQ    
Sbjct: 315 DALVGAG----IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDV-GQPGA- 368

Query: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
           + P + L       ++R+C L  + RSL+ GG   +++S+WDLAAP+  +K +L  +   
Sbjct: 369 KTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPA 427

Query: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGP 439
           C AL  + DA + F+  + G + +WDL++Q++VR  +G+ DG   I +  Y   +WTGG 
Sbjct: 428 CYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 487

Query: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
           D  +RCWD R   +  ++ F SQI SL H P +DW+ +GM +    +      +++ +  
Sbjct: 488 DNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHL 547

Query: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 559
            +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S NN+ +VT
Sbjct: 548 HESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVT 607

Query: 560 GSGE-HASVYQITY 572
           GSG+  A+VY++ Y
Sbjct: 608 GSGDKKATVYEVVY 621


>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
           sapiens]
          Length = 743

 Score =  218 bits (554), Expect = 2e-56
 Identities = 114/314 (36%), Positives = 182/314 (57%), Gaps = 10/314 (3%)

Query: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
           DAL G      +P    ++  LAHGE+V A  IS  T+HV+T G+  +KVW + GQ    
Sbjct: 437 DALVGAG----IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDV-GQPGA- 490

Query: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
           + P + L       ++R+C L  + RSL+ GG   +++S+WDLAAP+  +K +L  +   
Sbjct: 491 KTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPA 549

Query: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGP 439
           C AL  + DA + F+  + G + +WDL++Q++VR  +G+ DG   I +  Y   +WTGG 
Sbjct: 550 CYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 609

Query: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
           D  +RCWD R   +  ++ F SQI SL H P +DW+ +GM +    +      +++ +  
Sbjct: 610 DNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHL 669

Query: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 559
            +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S NN+ +VT
Sbjct: 670 HESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVT 729

Query: 560 GSGE-HASVYQITY 572
           GSG+  A+VY++ Y
Sbjct: 730 GSGDKKATVYEVVY 743


>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
          Length = 773

 Score =  203 bits (517), Expect = 3e-52
 Identities = 108/315 (34%), Positives = 180/315 (57%), Gaps = 10/315 (3%)

Query: 261 PDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAE 320
           PDAL G      +P    ++  L HGE+V A  IS+ TRHV+T G+  +KVW ++     
Sbjct: 466 PDALIGPG----IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHP--G 519

Query: 321 DRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGL 380
           ++ P S L       ++R+C L  + R+L+ GG   +++S+WDLAAP+  +K +L  +  
Sbjct: 520 NKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAP 578

Query: 381 NCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGG 438
            C AL  + D+ + F+  + G + +WDL +Q++VR  +G+ DG   I +   G  +WTGG
Sbjct: 579 ACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGG 638

Query: 439 PDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVG 498
            D  +R WD R   +  ++ F SQI SL + P  +W+ +GM N    +   +   ++ + 
Sbjct: 639 LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLH 698

Query: 499 QKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVV 558
             +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S +++ +V
Sbjct: 699 LHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIV 758

Query: 559 TGSGE-HASVYQITY 572
           TGSG+  A+VY++ Y
Sbjct: 759 TGSGDKKATVYEVIY 773


>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
           sapiens]
          Length = 769

 Score =  199 bits (505), Expect = 7e-51
 Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%)

Query: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
           DAL G      +P    ++  L+HGE+V A  IS+ TRHV+T G+  +K+W ++   ++ 
Sbjct: 463 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 518

Query: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
             P S L       ++R+C L  + R+L+ GG   +++++WDLA+P+  +K +L  +   
Sbjct: 519 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 575

Query: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 439
           C AL  + DA + F+  + G + +WDL +Q++VR  +G+ DG   I +   G  +WTGG 
Sbjct: 576 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 635

Query: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
           D  +R WD R   +  ++ F SQI SL + P  +W+ +GM +    +   +   ++ +  
Sbjct: 636 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 695

Query: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 559
            +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S++++ +VT
Sbjct: 696 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 755

Query: 560 GSGE-HASVYQITY 572
           GSG+  A+VY++ Y
Sbjct: 756 GSGDKKATVYEVIY 769


>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
           sapiens]
          Length = 760

 Score =  199 bits (505), Expect = 7e-51
 Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%)

Query: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
           DAL G      +P    ++  L+HGE+V A  IS+ TRHV+T G+  +K+W ++   ++ 
Sbjct: 454 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 509

Query: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
             P S L       ++R+C L  + R+L+ GG   +++++WDLA+P+  +K +L  +   
Sbjct: 510 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 566

Query: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 439
           C AL  + DA + F+  + G + +WDL +Q++VR  +G+ DG   I +   G  +WTGG 
Sbjct: 567 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 626

Query: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
           D  +R WD R   +  ++ F SQI SL + P  +W+ +GM +    +   +   ++ +  
Sbjct: 627 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 686

Query: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 559
            +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S++++ +VT
Sbjct: 687 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 746

Query: 560 GSGE-HASVYQITY 572
           GSG+  A+VY++ Y
Sbjct: 747 GSGDKKATVYEVIY 760


>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
           sapiens]
          Length = 772

 Score =  199 bits (505), Expect = 7e-51
 Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%)

Query: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
           DAL G      +P    ++  L+HGE+V A  IS+ TRHV+T G+  +K+W ++   ++ 
Sbjct: 466 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 521

Query: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
             P S L       ++R+C L  + R+L+ GG   +++++WDLA+P+  +K +L  +   
Sbjct: 522 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 578

Query: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 439
           C AL  + DA + F+  + G + +WDL +Q++VR  +G+ DG   I +   G  +WTGG 
Sbjct: 579 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 638

Query: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
           D  +R WD R   +  ++ F SQI SL + P  +W+ +GM +    +   +   ++ +  
Sbjct: 639 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 698

Query: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 559
            +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S++++ +VT
Sbjct: 699 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 758

Query: 560 GSGE-HASVYQITY 572
           GSG+  A+VY++ Y
Sbjct: 759 GSGDKKATVYEVIY 772


>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
          Length = 770

 Score =  198 bits (503), Expect = 1e-50
 Identities = 106/315 (33%), Positives = 179/315 (56%), Gaps = 10/315 (3%)

Query: 261 PDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAE 320
           PDAL G      +P    ++  L HGE+V A  IS+ TRHV+T G+  +KVW ++     
Sbjct: 463 PDALIGPG----IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHP--G 516

Query: 321 DRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGL 380
           ++ P S L       ++R+C L  +  +L+ GG   +++S+WDLAAP+  +K +L  +  
Sbjct: 517 NKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAP 575

Query: 381 NCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGG 438
            C AL  + D+ + F+  + G + +WDL +Q++VR  +G+ DG   I +   G  +WTGG
Sbjct: 576 ACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGG 635

Query: 439 PDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVG 498
            D  +R WD R   +  ++ F SQI SL + P  +W+ +GM +    +   +   ++ + 
Sbjct: 636 LDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLH 695

Query: 499 QKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVV 558
             +S +LS+KF+  G+W+ S G D+ L  +  P G  +F+  E S V  CD+S +++ +V
Sbjct: 696 LHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIV 755

Query: 559 TGSGE-HASVYQITY 572
           TGSG+  A+VY++ Y
Sbjct: 756 TGSGDKKATVYEVIY 770


>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
           sapiens]
          Length = 706

 Score =  162 bits (411), Expect = 6e-40
 Identities = 88/251 (35%), Positives = 143/251 (56%), Gaps = 9/251 (3%)

Query: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
           DAL G      +P    ++  LAHGE+V A  IS  T+HV+T G+  +KVW + GQ    
Sbjct: 451 DALVGAG----IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDV-GQPGA- 504

Query: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
           + P + L       ++R+C L  + RSL+ GG   +++S+WDLAAP+  +K +L  +   
Sbjct: 505 KTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPA 563

Query: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGP 439
           C AL  + DA + F+  + G + +WDL++Q++VR  +G+ DG   I +  Y   +WTGG 
Sbjct: 564 CYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 623

Query: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
           D  +RCWD R   +  ++ F SQI SL H P +DW+ +GM +    +      +++ +  
Sbjct: 624 DNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHL 683

Query: 500 KDSVILSVKFS 510
            +S +LS+KF+
Sbjct: 684 HESCVLSLKFA 694


>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
          Length = 655

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 49/223 (21%), Positives = 85/223 (38%), Gaps = 46/223 (20%)

Query: 344 SNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 403
           ++ R L TGG +   V++W +  P+  +   L       +++  N    L  A   SG +
Sbjct: 31  ASGRLLATGGDD-CRVNLWSINKPNCIMS--LTGHTSPVESVRLNTPEELIVAGSQSGSI 87

Query: 404 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYN--IWTGGPDACLRCWDQRTIMKPLEYQFKS 461
           R+WDL    ++R L G+   + S+    Y   + +G  D  ++ WD R       Y+  S
Sbjct: 88  RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHS 147

Query: 462 QIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGM 521
           Q                                         +  ++FSP G+W AS   
Sbjct: 148 Q----------------------------------------AVRCLRFSPDGKWLASAAD 167

Query: 522 DDFLGVYSMPAGTKVFEVP-EMSPVTCCDVSSNNRLVVTGSGE 563
           D  + ++ + AG  + E P    PV   +   N  L+ +GS +
Sbjct: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 340 CLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFT 399
           CL  S     L    +  +V +WDL A  +    + P        ++ + +  L  +  +
Sbjct: 152 CLRFSPDGKWLASAADDHTVKLWDLTAGKM--MSEFPGHTGPVNVVEFHPNEYLLASGSS 209

Query: 400 SGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDAC 442
              +R WDL    VV  ++G P  V+S++          PD C
Sbjct: 210 DRTIRFWDLEKFQVVSCIEGEPGPVRSVLF--------NPDGC 244


>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
           sapiens]
          Length = 504

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 5/132 (3%)

Query: 403 VRIWDLRDQSVVRDLKGYPDGVKSIVV--KGYNIWTGGPDACLRCWDQRTI--MKPLEYQ 458
           ++IWDL++++ V +  G+   + SI     GY + T   D+ ++ WD R +   K L+  
Sbjct: 374 IKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLD 433

Query: 459 FKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWAS 518
              ++ SL       ++ LG  + Q ++        H   +   +   V F    ++ AS
Sbjct: 434 NNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFT-EHSGLTTGVAFGHHAKFIAS 492

Query: 519 VGMDDFLGVYSM 530
            GMD  L  YS+
Sbjct: 493 TGMDRSLKFYSL 504


>gi|13376840 WD repeat domain 61 [Homo sapiens]
          Length = 305

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 26/188 (13%)

Query: 402 VVRIWDLRDQ--SVVRDLKGYPDGVKSIVVKGYN--IWTGGPDACLRCWDQRTIMKPLEY 457
           +V++W  RD+   +   L+G+  GV S+ +        +   DA +R WD          
Sbjct: 43  LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLEN------- 95

Query: 458 QFKSQIMSLSHSPQEDWVLLGMANGQQWLQST-----------SGSQRHMVGQKDSVILS 506
               QI S+   P + W L    + Q     T           SG + + +  +   ILS
Sbjct: 96  --GKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILS 153

Query: 507 VKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVP-EMSPVTCCDVSSNNRLVVTGSGE-H 564
           + +SP G++ AS  +D  + ++ +  G  +  +     P+     S +++L+VT S + +
Sbjct: 154 IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213

Query: 565 ASVYQITY 572
             +Y + +
Sbjct: 214 IKIYDVQH 221


>gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
          Length = 193

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 19/136 (13%)

Query: 319 AEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD------LAAPSLHVK 372
           AED+ P + +      A +   L S +SR + +  ++  S+ +WD      LA+   HV 
Sbjct: 67  AEDKKPLTRMTGHQ--ALINQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVA 123

Query: 373 EQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSI--VVK 430
                A         + D+ L  +  +   +++WD++ Q +  DL G+ D V ++     
Sbjct: 124 AVYQIAW--------SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPD 175

Query: 431 GYNIWTGGPDACLRCW 446
           G  + +GG D CLR W
Sbjct: 176 GQRVASGGKDKCLRIW 191


>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
          Length = 485

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 19/136 (13%)

Query: 319 AEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWD------LAAPSLHVK 372
           AED+ P + +      A +   L S +SR + +  ++  S+ +WD      LA+   HV 
Sbjct: 359 AEDKKPLTRMTGHQ--ALINQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVA 415

Query: 373 EQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSI--VVK 430
                A         + D+ L  +  +   +++WD++ Q +  DL G+ D V ++     
Sbjct: 416 AVYQIAW--------SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPD 467

Query: 431 GYNIWTGGPDACLRCW 446
           G  + +GG D CLR W
Sbjct: 468 GQRVASGGKDKCLRIW 483



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 37/169 (21%), Positives = 67/169 (39%), Gaps = 16/169 (9%)

Query: 285 HGELVLATAISSFTRHVFT-CGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLS 343
           H E V++ A S   +++ +  G   ++ W L+ +         H   +    ++ +   S
Sbjct: 113 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETP-------HFTCKGHRHWVLSISWS 165

Query: 344 SNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLP-----CAGLNCQALDANLDANLAFASF 398
            + R L +G  N   + +WD  +    V   L        GL+ + L AN +     +S 
Sbjct: 166 PDGRKLASGCKN-GQILLWD-PSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSS 223

Query: 399 TSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN-IWTGGPDACLRCW 446
             G VRIWD       R L G+   V  +   G   +++   D  ++ W
Sbjct: 224 KDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVW 272


>gi|8922301 WD repeat domain 70 [Homo sapiens]
          Length = 654

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 69/278 (24%), Positives = 108/278 (38%), Gaps = 42/278 (15%)

Query: 322 RFPESHLPIQTPGAFLRTCL-LSSNSRSLLTGGYNLASVSVWDLAAPSLHVK---EQLPC 377
           + P+SH      G    + L L  +   L+TGGY+   V  WD A      K      PC
Sbjct: 169 KIPDSHEITLKHGTKTVSALGLDPSGARLVTGGYDY-DVKFWDFAGMDASFKAFRSLQPC 227

Query: 378 AGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNI--- 434
                ++L  +   ++      S   ++ D     V+  +KG    V     KG+     
Sbjct: 228 ECHQIKSLQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLH 287

Query: 435 ---W---------TGGPDACLRCWD------QRTIMKPLEYQFKSQI-MSLSHSPQEDWV 475
              W         T   DA +R W+      Q+++ KP   Q K  I  + ++S   + +
Sbjct: 288 TGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLI 347

Query: 476 LLGMANG--QQWLQSTSG------SQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGV 527
                NG  Q W ++ +        Q H  G   S    V FS  G   AS G DD L +
Sbjct: 348 AAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSC---VTFSYDGNVLASRGGDDSLKL 404

Query: 528 YSMPAGTKVF----EVPEMSPVTCCDVSSNNRLVVTGS 561
           + +    K       +P M P+T C  S +++L+VTG+
Sbjct: 405 WDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGT 442


>gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]
          Length = 670

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 5/108 (4%)

Query: 340 CLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFT 399
           C L S+   L +G  +L ++ VWD+    L +K++L   GLN   + A + A     S +
Sbjct: 483 CTLVSSHNVLFSG--SLKAIKVWDIVGTELKLKKEL--TGLN-HWVRALVAAQSYLYSGS 537

Query: 400 SGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWD 447
              ++IWD+R    +  L+     V SI V  ++I  G  +  +  WD
Sbjct: 538 YQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWD 585



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 13/63 (20%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 392 NLAFASFTSGVVRIWDL-RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
           +L F+  +   +++WD        + L+G+   V ++ ++G  +++G  D  +  WD + 
Sbjct: 409 DLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQN 468

Query: 451 IMK 453
           + K
Sbjct: 469 LQK 471


>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
          Length = 357

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 6/151 (3%)

Query: 385 LDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYN---IWTGGPDA 441
           L  N D ++ F++ T   V +WD      V+ LKG+   V S          + TG  D 
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDG 174

Query: 442 CLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANG--QQWLQSTSGSQRHMVGQ 499
            ++ WD R       +Q   Q+++++ +   D ++ G  +   + W    +     M G 
Sbjct: 175 TVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGH 234

Query: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSM 530
            DSV   +  S  G +  S  MD+ + V+ +
Sbjct: 235 ADSV-TGLSLSSEGSYLLSNAMDNTVRVWDV 264


>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
          Length = 589

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 55/265 (20%), Positives = 107/265 (40%), Gaps = 38/265 (14%)

Query: 337 LRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQ---LPCAGLNCQALDANLDAN- 392
           L T  +S +S+ LL  G++ + + +W L +  L  +     +    L C  L+   D + 
Sbjct: 271 LNTAEISPDSK-LLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDEDD 329

Query: 393 ------------------LAFASFTSGV--------VRIWDLRDQSVVRDLKGYPDGVKS 426
                               F + +SG+        +R WDL   +     +G+   V  
Sbjct: 330 NAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWD 389

Query: 427 IVVKGYNIW--TGGPDACLRCWD-QRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANG- 482
           + +  Y+++  +G  D   R W   RT    +     + +  +   P  +++  G  +  
Sbjct: 390 LDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKT 449

Query: 483 -QQWLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEV-P 540
            + W      S R   G +  V LS+ FSP G++ AS G D  L ++ + +GT   E+  
Sbjct: 450 VRLWSAQQGNSVRLFTGHRGPV-LSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRG 508

Query: 541 EMSPVTCCDVSSNNRLVVTGSGEHA 565
               +T    S ++ L+ + S +++
Sbjct: 509 HTDNITSLTFSPDSGLIASASMDNS 533


>gi|18874090 WD repeat domain 48 [Homo sapiens]
          Length = 677

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 38/164 (23%), Positives = 65/164 (39%), Gaps = 17/164 (10%)

Query: 339 TCLLSSNSRSLLTGGYN-LASVSVWDLAAPSLHVKEQLPCAGL--------NCQALDANL 389
           T  LS N  S+ +   N L ++ V       L V +   CA L        N +AL  N 
Sbjct: 161 TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR 220

Query: 390 DANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKG--YNIWTGGPDACLRCWD 447
           D     +  + G +R+W L  Q  +   + + +GV ++ V     ++++GG D  + C D
Sbjct: 221 DGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD 280

Query: 448 QRT------IMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQW 485
            R       I +      K ++   +  P   WV    +   +W
Sbjct: 281 LRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKW 324


>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
           sapiens]
          Length = 522

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 12/167 (7%)

Query: 404 RIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRT--IMKPLEYQF 459
           R+WDL  Q  +   +G+  GV  I     G    TGG DA  R WD RT   +  LE   
Sbjct: 348 RLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407

Query: 460 KSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQR---HMVGQKDSVILSVKFSPF-GQW 515
           K +I  ++ SP    +  G  +G    +     QR   + +    +++  VKF P  G +
Sbjct: 408 K-EIYGINFSPNGYHIATG--SGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNF 464

Query: 516 WASVGMDDFLGVYSMPAGTKVFEVP-EMSPVTCCDVSSNNRLVVTGS 561
             +   D+   +++ P  + +  +      V   D+SS+ +L+ T S
Sbjct: 465 LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 511



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 39/150 (26%), Positives = 61/150 (40%), Gaps = 13/150 (8%)

Query: 303 TCGRRG-IKVWSLTGQVAEDRFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSV 361
           +C   G +K+WSL          E    I+     +   +   + R L T  Y+  S  +
Sbjct: 298 SCAADGSVKLWSLDSD-------EPVADIEGHTVRVARVMWHPSGRFLGTTCYD-RSWRL 349

Query: 362 WDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYP 421
           WDL A    + ++    G+   A   + D +LA         R+WDLR    +  L+G+ 
Sbjct: 350 WDLEAQEEILHQEGHSMGVYDIAF--HQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407

Query: 422 DGVKSI--VVKGYNIWTGGPDACLRCWDQR 449
             +  I     GY+I TG  D   + WD R
Sbjct: 408 KEIYGINFSPNGYHIATGSGDNTCKVWDLR 437


>gi|157266266 WD repeat domain 86 [Homo sapiens]
          Length = 376

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 2/107 (1%)

Query: 340 CLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFT 399
           C   + +  LL  G    +  VW +A+   H   +     + C  LD     + AF   T
Sbjct: 156 CAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDT--PGHTAFTGST 213

Query: 400 SGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCW 446
              +R WD+     +R  + +   V  + +    +++G  D  ++CW
Sbjct: 214 DATIRAWDILSGEQLRVFREHRGSVICLELVNRLVYSGSADRTVKCW 260



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 17/94 (18%)

Query: 356 LASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVR 415
           LA  + WDL  PS    E+    GL                  T G  ++W +      +
Sbjct: 143 LAYSAPWDL--PSTPCAEEAAAGGL-------------LVTGSTDGTAKVWQVASGCCHQ 187

Query: 416 DLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWD 447
            L+G+   V  +V+   G+  +TG  DA +R WD
Sbjct: 188 TLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWD 221


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 16/185 (8%)

Query: 384 ALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACL 443
           A+D   D++L    F    VR+W +  +  +R +K   D   S++ K         D   
Sbjct: 475 AVDVTDDSSLIAGGFADSTVRVWSVTPKK-LRSVKQASD--LSLIDK------ESDDVLE 525

Query: 444 RCWDQRTIMK-PLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQK-- 500
           R  D++T  +  + Y     +   S SP  +++L    +G   L S   +   +VG K  
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ-TFTCLVGYKGH 584

Query: 501 DSVILSVKFSPFGQWWASVGMDDFLGVYSMP--AGTKVFEVPEMSPVTCCDVSSNNRLVV 558
           +  +   +FSP+G ++ S G D    +++       ++F    ++ V C     N+  V 
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF-AGHLADVNCTRFHPNSNYVA 643

Query: 559 TGSGE 563
           TGS +
Sbjct: 644 TGSAD 648



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 11/180 (6%)

Query: 390 DANLAFASFTSGVVRIWDLRDQSVVRDLKG--YPDGVKSIVVKGYNIWTGGPDACLRCWD 447
           D N   +S   G VR+W L+  + +   KG  YP         GY   +GG D   R W 
Sbjct: 554 DRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW- 612

Query: 448 QRTIMKPLEYQFKSQIMSLS---HSPQEDWVLLGMANG--QQWLQSTSGSQRHMVGQKDS 502
                +PL   F   +  ++     P  ++V  G A+   + W        R   G K  
Sbjct: 613 ATDHYQPLRI-FAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHK-G 670

Query: 503 VILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTC-CDVSSNNRLVVTGS 561
            I S+ FSP G++ A+   D  + ++ +  G  V E+   +   C    S +  ++ +GS
Sbjct: 671 PIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGS 730



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 399 TSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRTIMKPLE 456
           T G V +WD+    +V +LKG+ D V S+     G  + +G  D  +R WD     + LE
Sbjct: 689 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLE 748


>gi|26665869 WD repeat domain 51B [Homo sapiens]
          Length = 478

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 23/170 (13%)

Query: 285 HGELVLATAISSFTRHVFTCGR-RGIKVWSLTGQVAEDRFPES-----HLPIQTPGAFLR 338
           H   V     S   R + +C   + IK+W  T +   + F +S      +     G    
Sbjct: 143 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG---- 198

Query: 339 TCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASF 398
           TC+ S+ S           +V VWD+    L    Q+   G+NC  +  +   N    + 
Sbjct: 199 TCIASAGSDQ---------TVKVWDVRVNKLLQHYQVHSGGVNC--ISFHPSGNYLITAS 247

Query: 399 TSGVVRIWDLRDQSVVRDLKGYPDGVKSI-VVKGYNIW-TGGPDACLRCW 446
           + G ++I DL +  ++  L+G+   V ++   KG  ++ +GG D  +  W
Sbjct: 248 SDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%)

Query: 410 DQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRTIMKPLEYQ-FKSQIMSL 466
           D  + R  KG+   + S+ +   G  + T   D  L  W+ +   +   Y   K  + S+
Sbjct: 7   DPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSV 66

Query: 467 SHSPQEDWVLLGMANGQQ----WLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMD 522
             SP  +  LL  A+  +    W+    G          + + SV FS  GQ+ A+   D
Sbjct: 67  QFSPHGN--LLASASRDRTVRLWIPDKRGKFSEFKAHT-APVRSVDFSADGQFLATASED 123

Query: 523 DFLGVYSMPAGTKVFEVPEMSP-VTCCDVSSNNRLVVTGS 561
             + V+SM     ++ +   +  V C   S + RL+V+ S
Sbjct: 124 KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCS 163


>gi|21281677 WD repeat domain 36 [Homo sapiens]
          Length = 951

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 47/207 (22%), Positives = 82/207 (39%), Gaps = 30/207 (14%)

Query: 380 LNCQALDANLDANLAFASFTSGVVRIWDLRDQ----SVVRDLKGYPDGVKSIVVKGYN-- 433
           +   A+D     N A    +SG V +++++      S  +D + +   V+ + V G N  
Sbjct: 495 ITATAVDITSCGNFAVIGLSSGTVDVYNMQSGIHRGSFGKD-QAHKGSVRGVAVDGLNQL 553

Query: 434 IWTGGPDACLRCWDQRTIMKPLEYQFKSQIM----SLSHSPQ-----EDWVLLGMANGQQ 484
             T G +  L+ W+           FK++I+    SLS SP       D  +LG+A    
Sbjct: 554 TVTTGSEGLLKFWN-----------FKNKILIHSVSLSSSPNIMLLHRDSGILGLALDDF 602

Query: 485 WLQSTSGSQRHMVGQ---KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPE 541
            +       R +V +       I  + FSP G+W  S  MD  +  + +P+G  +     
Sbjct: 603 SISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCSIRTWDLPSGCLIDCFLL 662

Query: 542 MSPVTCCDVSSNNRLVVTGSGEHASVY 568
            S      +S     + T   +H  +Y
Sbjct: 663 DSAPLNVSMSPTGDFLATSHVDHLGIY 689


>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
           sapiens]
          Length = 589

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 6/102 (5%)

Query: 350 LTGGYNLASVSVWDL-AAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDL 408
           +  G   A++ VWD+     LHV      A + C   D     + A+      +V++WD 
Sbjct: 356 VVSGSRDATLRVWDIETGQCLHVLMG-HVAAVRCVQYDGRRVVSGAY----DFMVKVWDP 410

Query: 409 RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
             ++ +  L+G+ + V S+   G ++ +G  D  +R WD  T
Sbjct: 411 ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVET 452



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 7/107 (6%)

Query: 345 NSRSLLTGGYNLASVSVWDLAAPS-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 403
           + R +++G Y+   V VWD    + LH  +     G   +      D     +      +
Sbjct: 392 DGRRVVSGAYDFM-VKVWDPETETCLHTLQ-----GHTNRVYSLQFDGIHVVSGSLDTSI 445

Query: 404 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
           R+WD+   + +  L G+      + +K   + +G  D+ ++ WD +T
Sbjct: 446 RVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKT 492



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 21/147 (14%)

Query: 309 IKVWSLTGQVAEDRFPESHLPIQT-PGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAP 367
           +KVW           PE+   + T  G   R   L  +   +++G  +  S+ VWD+   
Sbjct: 405 VKVWD----------PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLD-TSIRVWDVETG 453

Query: 368 S-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKS 426
           + +H        G         L  N+  +      V+IWD++    ++ L+G      +
Sbjct: 454 NCIHT-----LTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 508

Query: 427 IVVKGYN---IWTGGPDACLRCWDQRT 450
           +    +N   + T   D  ++ WD +T
Sbjct: 509 VTCLQFNKNFVITSSDDGTVKLWDLKT 535


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 6/102 (5%)

Query: 350 LTGGYNLASVSVWDL-AAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDL 408
           +  G   A++ VWD+     LHV      A + C   D     + A+      +V++WD 
Sbjct: 474 VVSGSRDATLRVWDIETGQCLHVLMG-HVAAVRCVQYDGRRVVSGAY----DFMVKVWDP 528

Query: 409 RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
             ++ +  L+G+ + V S+   G ++ +G  D  +R WD  T
Sbjct: 529 ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVET 570



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 7/107 (6%)

Query: 345 NSRSLLTGGYNLASVSVWDLAAPS-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 403
           + R +++G Y+   V VWD    + LH  +     G   +      D     +      +
Sbjct: 510 DGRRVVSGAYDFM-VKVWDPETETCLHTLQ-----GHTNRVYSLQFDGIHVVSGSLDTSI 563

Query: 404 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
           R+WD+   + +  L G+      + +K   + +G  D+ ++ WD +T
Sbjct: 564 RVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKT 610



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 21/147 (14%)

Query: 309 IKVWSLTGQVAEDRFPESHLPIQT-PGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAP 367
           +KVW           PE+   + T  G   R   L  +   +++G  +  S+ VWD+   
Sbjct: 523 VKVWD----------PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLD-TSIRVWDVETG 571

Query: 368 S-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKS 426
           + +H        G         L  N+  +      V+IWD++    ++ L+G      +
Sbjct: 572 NCIHT-----LTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 626

Query: 427 IVVKGYN---IWTGGPDACLRCWDQRT 450
           +    +N   + T   D  ++ WD +T
Sbjct: 627 VTCLQFNKNFVITSSDDGTVKLWDLKT 653


>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
           sapiens]
          Length = 627

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 6/102 (5%)

Query: 350 LTGGYNLASVSVWDL-AAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDL 408
           +  G   A++ VWD+     LHV      A + C   D     + A+      +V++WD 
Sbjct: 394 VVSGSRDATLRVWDIETGQCLHVLMG-HVAAVRCVQYDGRRVVSGAY----DFMVKVWDP 448

Query: 409 RDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
             ++ +  L+G+ + V S+   G ++ +G  D  +R WD  T
Sbjct: 449 ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVET 490



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 7/107 (6%)

Query: 345 NSRSLLTGGYNLASVSVWDLAAPS-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVV 403
           + R +++G Y+   V VWD    + LH  +     G   +      D     +      +
Sbjct: 430 DGRRVVSGAYDFM-VKVWDPETETCLHTLQ-----GHTNRVYSLQFDGIHVVSGSLDTSI 483

Query: 404 RIWDLRDQSVVRDLKGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRT 450
           R+WD+   + +  L G+      + +K   + +G  D+ ++ WD +T
Sbjct: 484 RVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKT 530



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 21/147 (14%)

Query: 309 IKVWSLTGQVAEDRFPESHLPIQT-PGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAP 367
           +KVW           PE+   + T  G   R   L  +   +++G  +  S+ VWD+   
Sbjct: 443 VKVWD----------PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLD-TSIRVWDVETG 491

Query: 368 S-LHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKS 426
           + +H        G         L  N+  +      V+IWD++    ++ L+G      +
Sbjct: 492 NCIHT-----LTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 546

Query: 427 IVVKGYN---IWTGGPDACLRCWDQRT 450
           +    +N   + T   D  ++ WD +T
Sbjct: 547 VTCLQFNKNFVITSSDDGTVKLWDLKT 573


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 359  VSVWDLAAPSLHVKEQLPCAGLNCQ-ALDANLDANLAFASFTSGVVRIWDLRDQSVVRDL 417
            +  WDL    L   +Q+P A  +   AL    D  +  +    G++++W++     V ++
Sbjct: 1552 IKKWDLTQKDL--LQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEM 1609

Query: 418  KGYPDGVKSIVVKGYNIWTGGPDACLRCWDQRTI 451
            KG+   + +I V   +I+T   D  +R W  R +
Sbjct: 1610 KGHDSPINAICVNSTHIFTAADDRTVRIWKARNL 1643



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 46/228 (20%), Positives = 90/228 (39%), Gaps = 23/228 (10%)

Query: 278  EKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAEDRFPESHLPIQTPGAFL 337
            E M +  H   V++    ++T  VFT     IKVW +       R   S   +    A  
Sbjct: 1366 EIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACS 1425

Query: 338  ----RTCLLSSNSRSLL------TGGYNLAS----VSVWDLAAPSLHVKEQLPCAGLNCQ 383
                RT  + S    +       TG +  A+    V +WDL       K       + C 
Sbjct: 1426 ASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCL 1485

Query: 384  ALDA-NLDANLAFASFTSGVVRIWDLRDQSV--VRDLKGYP----DGVKSIVVKGYNIWT 436
             +D  +   +L         ++++D+ + ++  V     +     DG++++ ++G N+++
Sbjct: 1486 TVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFS 1545

Query: 437  GGPDACLRCWD--QRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANG 482
            G  D  ++ WD  Q+ +++ +    K  + +L   P    +L G   G
Sbjct: 1546 GSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGG 1593


>gi|41281564 WD repeat domain 37 [Homo sapiens]
          Length = 494

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 393 LAFASFTSGVVRIWDLRDQSV--VRDLKGYPDGVKSIV-VKGYNIWTGGPDACLRCWDQR 449
           L   S      R+WD RD S+  V   +G+ D V S V   G N+ +G  D  ++ WD +
Sbjct: 337 LVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLK 396

Query: 450 TIMKPL 455
            +  P+
Sbjct: 397 NMRSPI 402


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,316,267
Number of Sequences: 37866
Number of extensions: 1382083
Number of successful extensions: 7696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 7259
Number of HSP's gapped (non-prelim): 543
length of query: 572
length of database: 18,247,518
effective HSP length: 108
effective length of query: 464
effective length of database: 14,157,990
effective search space: 6569307360
effective search space used: 6569307360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.