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Search of human proteins with 115387114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115387114 islet-1 [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115387114 islet-1 [Homo sapiens] 725 0.0
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 551 e-157
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 176 2e-44
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 176 2e-44
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 168 8e-42
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 167 1e-41
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 166 4e-41
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 165 6e-41
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 163 2e-40
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 162 5e-40
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 161 9e-40
gi|50083287 LIM homeobox 8 [Homo sapiens] 160 1e-39
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 158 8e-39
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 158 8e-39
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 158 8e-39
gi|5803072 LIM domain only 4 [Homo sapiens] 106 4e-23
gi|21361802 LIM domain only 3 [Homo sapiens] 102 7e-22
gi|47778935 LIM domain only 3 [Homo sapiens] 102 7e-22
gi|4505005 LIM domain only 1 [Homo sapiens] 101 1e-21
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 89 4e-18
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 89 4e-18
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 89 4e-18
gi|4505001 LIM domain kinase 1 [Homo sapiens] 80 2e-15
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 79 5e-15
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 79 5e-15
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 79 5e-15
gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens] 76 5e-14
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 74 2e-13
gi|194272207 actin binding LIM protein family, member 2 isoform ... 71 2e-12
gi|153792514 actin binding LIM protein family, member 2 isoform ... 71 2e-12
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 725 bits (1872), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV 60
MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV
Sbjct: 1 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV 60
Query: 61 RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF 120
RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF
Sbjct: 61 RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF 120
Query: 121 ALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEK 180
ALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEK
Sbjct: 121 ALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEK 180
Query: 181 TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS 240
TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS
Sbjct: 181 TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS 240
Query: 241 IMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQ 300
IMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQ
Sbjct: 241 IMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQ 300
Query: 301 SDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA 349
SDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
Sbjct: 301 SDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA 349
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 551 bits (1421), Expect = e-157
Identities = 264/349 (75%), Positives = 301/349 (86%), Gaps = 2/349 (0%)
Query: 1 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV 60
+G MGD KKK ++CVGCG+QIHDQ+ILRVSPDLEWHAACLKCAEC+QYLDE+CTCFV
Sbjct: 11 LGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFV 70
Query: 61 RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF 120
RDGKTYCKRDY+RL+GIKCAKC +GFS +D VMRAR VYHIECFRC CSRQL+PGDEF
Sbjct: 71 RDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEF 130
Query: 121 ALREDGLFCRADHDVV-ERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPE 179
+LRE L CRADH ++ ERA+ G+ PL AR L + + S RQPALRPHVHKQ E
Sbjct: 131 SLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP-DAGSGRQPALRPHVHKQTE 189
Query: 180 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR 239
KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+
Sbjct: 190 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKK 249
Query: 240 SIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFAL 299
SI+MKQLQQQQ +DKT++QG+TGTP+VA SP RH+ +Q + VEVQ+YQPPWK LS+FAL
Sbjct: 250 SILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFAL 309
Query: 300 QSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIE 348
QSD+DQPAFQQLV+FSE G NS+GS+V S+SSQLPDTPNSMV SP+E
Sbjct: 310 QSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVE 358
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 176 bits (447), Expect = 2e-44
Identities = 96/270 (35%), Positives = 140/270 (51%), Gaps = 36/270 (13%)
Query: 3 DMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRD 62
D G PP +LC GCG +I D+Y L ++ D +WH CLKC EC L+ TCF +D
Sbjct: 57 DAGMPPLSPEKPALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKD 115
Query: 63 GKTYCKRDYIRLYGI-KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFA 121
G YCK DY R + + +CA+C +G S ++ VMRAR VYH+ CF C C++ L GD F
Sbjct: 116 GSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG 175
Query: 122 LREDGLFCRADHDVV------------ERASLGAGDPLSPLHPARPLQMAAEPISARQPA 169
+++ ++CRA + + E A+ G L + +Q P + PA
Sbjct: 176 MKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQ-KGRPRKRKSPA 234
Query: 170 LRPHV-----------------HKQP----EKTTRVRTVLNEKQLHTLRTCYAANPRPDA 208
L + +QP +KT R+RT QL T+++ +A N PDA
Sbjct: 235 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA 294
Query: 209 LMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
+QL + TGL+ RV++VWFQN R K ++
Sbjct: 295 KDLKQLAQKTGLTKRVLQVWFQNARAKFRR 324
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 176 bits (447), Expect = 2e-44
Identities = 96/270 (35%), Positives = 140/270 (51%), Gaps = 36/270 (13%)
Query: 3 DMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRD 62
D G PP +LC GCG +I D+Y L ++ D +WH CLKC EC L+ TCF +D
Sbjct: 48 DAGMPPLSPEKPALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKD 106
Query: 63 GKTYCKRDYIRLYGI-KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFA 121
G YCK DY R + + +CA+C +G S ++ VMRAR VYH+ CF C C++ L GD F
Sbjct: 107 GSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG 166
Query: 122 LREDGLFCRADHDVV------------ERASLGAGDPLSPLHPARPLQMAAEPISARQPA 169
+++ ++CRA + + E A+ G L + +Q P + PA
Sbjct: 167 MKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQ-KGRPRKRKSPA 225
Query: 170 LRPHV-----------------HKQP----EKTTRVRTVLNEKQLHTLRTCYAANPRPDA 208
L + +QP +KT R+RT QL T+++ +A N PDA
Sbjct: 226 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA 285
Query: 209 LMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
+QL + TGL+ RV++VWFQN R K ++
Sbjct: 286 KDLKQLAQKTGLTKRVLQVWFQNARAKFRR 315
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 168 bits (425), Expect = 8e-42
Identities = 96/251 (38%), Positives = 139/251 (55%), Gaps = 16/251 (6%)
Query: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
S+C GC I D+++LR++ D WH C++CA C + L+ TCF RD K YCK DY +L
Sbjct: 33 SVCEGCQRVILDRFLLRLN-DSFWHEQCVQCASCKEPLET--TCFYRDKKLYCKYDYEKL 89
Query: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHD 134
+ +KC C + N+FVMRA+ VYH+ CF C C RQL GDEF L+E L C+ D++
Sbjct: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
Query: 135 VVERASLGAGDPLS----PLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNE 190
ER L P + L +A + + A HK+P+ R RT+L
Sbjct: 150 -KERELLSLVSPAASDSGKSDDEESLCKSAHG-AGKGTAEEGKDHKRPK---RPRTILTT 204
Query: 191 KQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQ 250
+Q + + + +P ++E L TGLS RV++VWFQN+R K KK + + QQQQ
Sbjct: 205 QQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK----LARRQQQQ 260
Query: 251 PNDKTNIQGMT 261
D+ N Q ++
Sbjct: 261 QQDQQNTQRLS 271
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 167 bits (424), Expect = 1e-41
Identities = 102/306 (33%), Positives = 151/306 (49%), Gaps = 56/306 (18%)
Query: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
+LC GCG +I D+Y L ++ D +WH CLKC EC L+ TCF +DG YCK DY R
Sbjct: 51 ALCAGCGGKISDRYYL-LAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRR 109
Query: 75 YGI-KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133
+ + +CA+C +G S ++ VMRAR VYH+ CF C C++ L GD F +++ ++CR
Sbjct: 110 FSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHF 169
Query: 134 DVV------------------------ERASLGA--GDPL--------SPLHPARPLQMA 159
+ + + A LGA +PL + RP +
Sbjct: 170 EALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRK 229
Query: 160 A----EPISARQPAL-----------RPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANP 204
+ ++A AL R + +KT R+RT QL T+++ +A N
Sbjct: 230 SPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINH 289
Query: 205 RPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDK-TNIQGMTGT 263
PDA +QL + TGL+ RV++VWFQN R K ++ + Q+ DK T+ TGT
Sbjct: 290 NPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLR----QENTGVDKSTDAALQTGT 345
Query: 264 PMVAAS 269
P AS
Sbjct: 346 PSGPAS 351
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 166 bits (419), Expect = 4e-41
Identities = 107/337 (31%), Positives = 167/337 (49%), Gaps = 24/337 (7%)
Query: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
++C GC I D++++RV+ + WH CL+CA C Q L SC + RD K YCK+DY +L
Sbjct: 31 AVCEGCQRPISDRFLMRVN-ESSWHEECLQCAACQQALTTSC--YFRDRKLYCKQDYQQL 87
Query: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH- 133
+ KC+ C + +FVMRA VYH+ CF C C RQL GDEF L+E L C+ D+
Sbjct: 88 FAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYE 147
Query: 134 ---DVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNE 190
D++ S D + ++ A Q K P + R RT+L
Sbjct: 148 KEKDLLSSVSPDESDSVKSEDEDGDMKPAKG--QGSQSKGSGDDGKDPRRPKRPRTILTT 205
Query: 191 KQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQ 250
+Q + + + +P ++E L TGLS RV++VWFQN+R K KK + +Q Q+QQ
Sbjct: 206 QQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQ 265
Query: 251 PNDK-------TNIQGMTGTPMVAASPERHDGGLQANPVE-----VQSYQPPWKVLSDFA 298
+ + + ++GM + A P++ ++ +P Q PP +D +
Sbjct: 266 NSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGND-S 324
Query: 299 LQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQL 335
+ DID L + S+ GS+ GS A + + +
Sbjct: 325 IFHDIDSDT--SLTSLSDCFLGSSDVGSLQARVGNPI 359
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 165 bits (417), Expect = 6e-41
Identities = 93/245 (37%), Positives = 135/245 (55%), Gaps = 22/245 (8%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYG 76
C GC I D+++L V D WH C++C EC L E C F R+GK YCK D+ R +G
Sbjct: 4 CAGCKRPILDRFLLNVL-DRAWHVKCVQCCECKCNLTEKC--FSREGKLYCKNDFFRCFG 60
Query: 77 IKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDE-FALREDGLFCRADH-- 133
KCA C+ G S +D V RARSKV+H+ CF C+ C++QL G+E + + E+ C+ D+
Sbjct: 61 TKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLS 120
Query: 134 -------DVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPE-----KT 181
+ + A+ G+ LSP A + SA ++ + K
Sbjct: 121 NSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKR 180
Query: 182 TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSI 241
RT + KQL TL+ +AA P+P ++EQL + TGL+ RVI+VWFQN+R K+++
Sbjct: 181 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR--- 237
Query: 242 MMKQL 246
MKQL
Sbjct: 238 -MKQL 241
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 163 bits (413), Expect = 2e-40
Identities = 110/336 (32%), Positives = 166/336 (49%), Gaps = 41/336 (12%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYG 76
C GC I D+++L V D WH C++C EC L E C F R+GK YCK D+ R +G
Sbjct: 5 CAGCERPILDRFLLNVL-DRAWHIKCVQCCECKTNLSEKC--FSREGKLYCKNDFFRRFG 61
Query: 77 IKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDE-FALREDGLFCRADH-- 133
KCA C+ G S +D V +ARSKV+H+ CF C+ C++QL G+E + + E+ C+ D+
Sbjct: 62 TKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLS 121
Query: 134 -DVVERASLGAGDPLSPLHPARPLQMAAE--------PISARQPALRPHVHKQPEKTTR- 183
++ SL + + + LQ A + S+ + +Q T R
Sbjct: 122 SSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRR 181
Query: 184 -VRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIM 242
RT + KQL TL+ +AA P+P ++EQL + TGL+ RVI+VWFQN+R K+++
Sbjct: 182 GPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR---- 237
Query: 243 MKQLQQ---------QQPNDKTNIQG-MTGTPMVAASPERHDGGLQANPVEVQSYQPPWK 292
MKQL + P + G + + M+ ++P + G Q + Y P
Sbjct: 238 MKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGD------YYAPGS 291
Query: 293 VLSDFA--LQSDIDQPAFQQLVNFSEGGPGSNSTGS 326
FA S PA + + GPGS G+
Sbjct: 292 NYDFFAHGPPSQAQSPADSSFL--AASGPGSTPLGA 325
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 162 bits (409), Expect = 5e-40
Identities = 87/229 (37%), Positives = 121/229 (52%), Gaps = 40/229 (17%)
Query: 11 KRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRD 70
+R I LC GC I D++IL+ D WH+ CLKC++C+ L E C F R YCK D
Sbjct: 30 RREIPLCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDD 86
Query: 71 YIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFC 129
+ + +G KCA C +G V RA+ VYH+ CF CV C RQL GDEF L ED L C
Sbjct: 87 FFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVC 146
Query: 130 RADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLN 189
+AD++ ++ A +A++P RT +
Sbjct: 147 KADYETAKQREAEA--------------------TAKRP----------------RTTIT 170
Query: 190 EKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
KQL TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 171 AKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 219
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 161 bits (407), Expect = 9e-40
Identities = 87/228 (38%), Positives = 120/228 (52%), Gaps = 40/228 (17%)
Query: 12 RLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDY 71
R I LC GC I D++IL+ D WH+ CLKC++C+ L E C F R YCK D+
Sbjct: 26 REIPLCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDDF 82
Query: 72 IRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFCR 130
+ +G KCA C +G V RA+ VYH+ CF CV C RQL GDEF L ED L C+
Sbjct: 83 FKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCK 142
Query: 131 ADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNE 190
AD++ ++ A +A++P RT +
Sbjct: 143 ADYETAKQREAEA--------------------TAKRP----------------RTTITA 166
Query: 191 KQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
KQL TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 167 KQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 160 bits (406), Expect = 1e-39
Identities = 93/268 (34%), Positives = 130/268 (48%), Gaps = 33/268 (12%)
Query: 5 GDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGK 64
G PP K +C CG +I D+Y+L+V+ DL WH CL C+ C L +C+++D
Sbjct: 67 GCPPGK----CVCNSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKDKD 121
Query: 65 TYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALRE 124
+CK DY R YG +C++C D+V RA+ VYH+ CF C +C RQL G+EFAL E
Sbjct: 122 IFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVE 181
Query: 125 DGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRV 184
+ + CR +D + L + IS L P+ R
Sbjct: 182 EKVLCRVHYDCM-------------LDNLKREVENGNGISVEGALLTEQDVNHPKPAKRA 228
Query: 185 RTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMK 244
RT QL ++ +A + PDA ++L E TGLS RVI+VWFQN R + KK
Sbjct: 229 RTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK------ 282
Query: 245 QLQQQQPNDKTNIQGMTGTPMVAASPER 272
PN ++ TP+ A P R
Sbjct: 283 ---HVSPNHSSS------TPVTAVPPSR 301
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 158 bits (399), Expect = 8e-39
Identities = 81/228 (35%), Positives = 126/228 (55%), Gaps = 19/228 (8%)
Query: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
++C CG +I D+Y+L+V+ +L WH CL+C+ C L + +C++++ + +CK DY
Sbjct: 97 NICSSCGLEILDRYLLKVN-NLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSR 155
Query: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHD 134
+G KCA+C +D+V RAR YH+ CF C +C RQL G+EF L E+ + CR +D
Sbjct: 156 FGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
Query: 135 VVERASLGAGDPLSPLHPARPLQMAAEPIS--ARQPALRPHVHKQPEKTTRVRTVLNEKQ 192
+ L+ AAE + + A+ QP+ R RT +Q
Sbjct: 216 TM----------------IENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQ 259
Query: 193 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS 240
L ++ +A + PDA ++L +MTGLS RVI+VWFQN R + KK +
Sbjct: 260 LQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHT 307
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 158 bits (399), Expect = 8e-39
Identities = 81/228 (35%), Positives = 126/228 (55%), Gaps = 19/228 (8%)
Query: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
++C CG +I D+Y+L+V+ +L WH CL+C+ C L + +C++++ + +CK DY
Sbjct: 97 NICSSCGLEILDRYLLKVN-NLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSR 155
Query: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHD 134
+G KCA+C +D+V RAR YH+ CF C +C RQL G+EF L E+ + CR +D
Sbjct: 156 FGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
Query: 135 VVERASLGAGDPLSPLHPARPLQMAAEPIS--ARQPALRPHVHKQPEKTTRVRTVLNEKQ 192
+ L+ AAE + + A+ QP+ R RT +Q
Sbjct: 216 TM----------------IENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQ 259
Query: 193 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS 240
L ++ +A + PDA ++L +MTGLS RVI+VWFQN R + KK +
Sbjct: 260 LQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHT 307
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 158 bits (399), Expect = 8e-39
Identities = 84/226 (37%), Positives = 116/226 (51%), Gaps = 39/226 (17%)
Query: 14 ISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIR 73
I C GC I D++IL+V D WH++CLKCA+C L + C F R G YCK D+ +
Sbjct: 27 IPQCAGCNQHILDKFILKVL-DRHWHSSCLKCADCQMQLADRC--FSRAGSVYCKEDFFK 83
Query: 74 LYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFCRAD 132
+G KC C G V +A+ VYH+ CF C+ C+RQL GDEF L EDG L C+ D
Sbjct: 84 RFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKED 143
Query: 133 HDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQ 192
++ + Q A++P RT + KQ
Sbjct: 144 YETAK-------------------QNDDSEAGAKRP----------------RTTITAKQ 168
Query: 193 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
L TL+ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 169 LETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 106 bits (264), Expect = 4e-23
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 4/119 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYL-DESCTCFVRDGKTYCKRDYIRLY 75
C GCG +I D+++L + D WH+ CLKC+ C L D +C+ + G C+ DYIRL+
Sbjct: 23 CAGCGGKIADRFLL-YAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLF 81
Query: 76 GIK--CAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRAD 132
G C+ C ++ VMRA+ VYH++CF C C +L+PGD F LFC D
Sbjct: 82 GNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHD 140
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 102 bits (253), Expect = 7e-22
Identities = 47/121 (38%), Positives = 72/121 (59%), Gaps = 4/121 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLY 75
C GC +I D+Y+L+ D WH CLKCA C+ L E T + + C+RDY+RL+
Sbjct: 13 CAGCNRKIKDRYLLKAL-DKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLF 71
Query: 76 GI--KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133
G+ CA CS + VMRA+ VYH++CF C C+++ GD+F L+ + + C+ D+
Sbjct: 72 GVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDY 131
Query: 134 D 134
+
Sbjct: 132 E 132
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 102 bits (253), Expect = 7e-22
Identities = 47/121 (38%), Positives = 72/121 (59%), Gaps = 4/121 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLY 75
C GC +I D+Y+L+ D WH CLKCA C+ L E T + + C+RDY+RL+
Sbjct: 13 CAGCNRKIKDRYLLKAL-DKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLF 71
Query: 76 GI--KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133
G+ CA CS + VMRA+ VYH++CF C C+++ GD+F L+ + + C+ D+
Sbjct: 72 GVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDY 131
Query: 134 D 134
+
Sbjct: 132 E 132
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 101 bits (251), Expect = 1e-21
Identities = 48/121 (39%), Positives = 71/121 (58%), Gaps = 4/121 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLY 75
C GC +I D+Y+L+ D WH CLKCA C+ L E T + + C+RDY+RL+
Sbjct: 24 CAGCNRKIKDRYLLKAL-DKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLF 82
Query: 76 GI--KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADH 133
G CA CS + VMRAR VYH++CF C C+++ GD+F L+ + + C+ D+
Sbjct: 83 GTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDY 142
Query: 134 D 134
+
Sbjct: 143 E 143
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 89.4 bits (220), Expect = 4e-18
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLY 75
C GC I D+Y L+ D WH CL C C L E + + G+ C+RDY+RL+
Sbjct: 30 CGGCQQNIGDRYFLKAI-DQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLF 88
Query: 76 GIK--CAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRAD 132
G CA C + MR + KVYH+ECF+C AC + GD + L + C D
Sbjct: 89 GQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 147
Score = 29.3 bits (64), Expect = 5.5
Identities = 13/55 (23%), Positives = 22/55 (40%)
Query: 16 LCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRD 70
LC C +I + D +H C KCA C ++ + + C++D
Sbjct: 93 LCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 147
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 89.4 bits (220), Expect = 4e-18
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLY 75
C GC I D+Y L+ D WH CL C C L E + + G+ C+RDY+RL+
Sbjct: 30 CGGCQQNIGDRYFLKAI-DQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLF 88
Query: 76 GIK--CAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRAD 132
G CA C + MR + KVYH+ECF+C AC + GD + L + C D
Sbjct: 89 GQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 147
Score = 29.3 bits (64), Expect = 5.5
Identities = 13/55 (23%), Positives = 22/55 (40%)
Query: 16 LCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRD 70
LC C +I + D +H C KCA C ++ + + C++D
Sbjct: 93 LCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 147
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 89.4 bits (220), Expect = 4e-18
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLY 75
C GC I D+Y L+ D WH CL C C L E + + G+ C+RDY+RL+
Sbjct: 99 CGGCQQNIGDRYFLKAI-DQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLF 157
Query: 76 GIK--CAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRAD 132
G CA C + MR + KVYH+ECF+C AC + GD + L + C D
Sbjct: 158 GQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 216
Score = 29.3 bits (64), Expect = 5.5
Identities = 13/55 (23%), Positives = 22/55 (40%)
Query: 16 LCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRD 70
LC C +I + D +H C KCA C ++ + + C++D
Sbjct: 162 LCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 216
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 80.5 bits (197), Expect = 2e-15
Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 7/118 (5%)
Query: 14 ISLCVGCGNQIHD-QYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYI 72
+ +C CG +I+D QY+ ++ D WHA C +C +C+ L + +DG+ +CK+DY
Sbjct: 22 LPVCASCGQRIYDGQYLQALNAD--WHADCFRCCDCSASLSHQY--YEKDGQLFCKKDYW 77
Query: 73 RLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFC 129
YG C CS +K VM A YH ECF C+ C + GD + L E L+C
Sbjct: 78 ARYGESCHGCSEQITKG-LVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC 134
Score = 35.0 bits (79), Expect = 0.100
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 12/66 (18%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYG 76
C GC QI ++ V+ +L++H C C C F+ DG TY ++ +LY
Sbjct: 84 CHGCSEQITKGLVM-VAGELKYHPECFICLTCGT--------FIGDGDTYTLVEHSKLY- 133
Query: 77 IKCAKC 82
C C
Sbjct: 134 --CGHC 137
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 79.3 bits (194), Expect = 5e-15
Identities = 41/120 (34%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 4 MGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDG 63
M PK+ S C GCG I + L ++ D +WH C KC C + L +DG
Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQAL-LALDKQWHLGCFKCKSCGKVLTGEYIS--KDG 209
Query: 64 KTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALR 123
YC++DY L+G+KC C + V+ A K YH C RC C++ G+E L+
Sbjct: 210 APYCEKDYQGLFGVKCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQ 267
Score = 61.6 bits (148), Expect = 1e-09
Identities = 39/123 (31%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
Query: 8 PKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYC 67
P +K +I C CG + +LRV +H C C C L + F+++G+ C
Sbjct: 31 PSEKPVIH-CHKCGEPCKGE-VLRVQTK-HFHIKCFTCKVCGCDLAQG-GFFIKNGEYLC 86
Query: 68 KRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGL 127
DY R+YG +C C G V+ A K YH CF C C R PGD
Sbjct: 87 TLDYQRMYGTRCHGC--GEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 144
Query: 128 FCR 130
C+
Sbjct: 145 LCQ 147
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 79.3 bits (194), Expect = 5e-15
Identities = 41/120 (34%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 4 MGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDG 63
M PK+ S C GCG I + L ++ D +WH C KC C + L +DG
Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQAL-LALDKQWHLGCFKCKSCGKVLTGEYIS--KDG 209
Query: 64 KTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALR 123
YC++DY L+G+KC C + V+ A K YH C RC C++ G+E L+
Sbjct: 210 APYCEKDYQGLFGVKCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQ 267
Score = 61.6 bits (148), Expect = 1e-09
Identities = 39/123 (31%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
Query: 8 PKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYC 67
P +K +I C CG + +LRV +H C C C L + F+++G+ C
Sbjct: 31 PSEKPVIH-CHKCGEPCKGE-VLRVQTK-HFHIKCFTCKVCGCDLAQG-GFFIKNGEYLC 86
Query: 68 KRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGL 127
DY R+YG +C C G V+ A K YH CF C C R PGD
Sbjct: 87 TLDYQRMYGTRCHGC--GEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 144
Query: 128 FCR 130
C+
Sbjct: 145 LCQ 147
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 79.3 bits (194), Expect = 5e-15
Identities = 41/120 (34%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 4 MGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDG 63
M PK+ S C GCG I + L ++ D +WH C KC C + L +DG
Sbjct: 213 MSSSPKETTFSSNCAGCGRDIKNGQAL-LALDKQWHLGCFKCKSCGKVLTGEYIS--KDG 269
Query: 64 KTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALR 123
YC++DY L+G+KC C + V+ A K YH C RC C++ G+E L+
Sbjct: 270 APYCEKDYQGLFGVKCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQ 327
Score = 61.6 bits (148), Expect = 1e-09
Identities = 39/123 (31%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
Query: 8 PKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYC 67
P +K +I C CG + +LRV +H C C C L + F+++G+ C
Sbjct: 91 PSEKPVIH-CHKCGEPCKGE-VLRVQTK-HFHIKCFTCKVCGCDLAQG-GFFIKNGEYLC 146
Query: 68 KRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGL 127
DY R+YG +C C G V+ A K YH CF C C R PGD
Sbjct: 147 TLDYQRMYGTRCHGC--GEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 204
Query: 128 FCR 130
C+
Sbjct: 205 LCQ 207
>gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens]
Length = 638
Score = 75.9 bits (185), Expect = 5e-14
Identities = 55/212 (25%), Positives = 91/212 (42%), Gaps = 7/212 (3%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYG 76
C GCG+ I I + + WH +C +C+EC L + +DGK YC +DY +G
Sbjct: 12 CPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSLTN--WYYEKDGKLYCPKDYWGKFG 69
Query: 77 IKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFCRADHDV 135
C CS+ F++ K YH ECF C++C + GD +AL + L+C H+
Sbjct: 70 EFCHGCSL-LMTGPFMVAGEFK-YHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNE 127
Query: 136 VERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHT 195
V A + + P + + A R + T + K+++
Sbjct: 128 VVLAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVN- 186
Query: 196 LRTCYAANPRPDALMKEQLVEMTGLSPRVIRV 227
R + N R ++++E+ G R +RV
Sbjct: 187 -RMHISPNNRNAIHPGDRILEINGTPVRTLRV 217
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 73.9 bits (180), Expect = 2e-13
Identities = 44/116 (37%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 8 PKKKRLISLCVGCGNQI-HDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTY 66
P K R S C GC +I H Q +L + D +WH +C KC C+ L +DG Y
Sbjct: 142 PIKIRGPSHCAGCKEEIKHGQSLLAL--DKQWHVSCFKCQTCSVILTGEYIS--KDGVPY 197
Query: 67 CKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFAL 122
C+ DY +GIKC C S V+ A K YH C RCV C + G+E L
Sbjct: 198 CESDYHAQFGIKCETCDRYISGR--VLEAGGKHYHPTCARCVRCHQMFTEGEEMYL 251
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 13/127 (10%)
Query: 8 PKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYC 67
P+ + C CG+ + ++RV + +H C C C L +S F ++ + C
Sbjct: 14 PRGSSNVIQCYRCGDTCKGE-VVRVHNN-HFHIRCFTCQVCGCGLAQS-GFFFKNQEYIC 70
Query: 68 KRDYIRLYGIKCAKCSIGFSKNDF----VMRARSKVYHIECFRCVACSRQLIPGDEFALR 123
+DY +LYG +C C DF V+ A + YH +CF C C + GD+
Sbjct: 71 TQDYQQLYGTRCDSC------RDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFS 124
Query: 124 EDGLFCR 130
C+
Sbjct: 125 GKECVCQ 131
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 70.9 bits (172), Expect = 2e-12
Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYG 76
C GCG +I + L V+ D WH C KC C + L+ +DG YC+ DY +G
Sbjct: 153 CGGCGTEIKNGQAL-VALDKHWHLGCFKCKSCGKLLNAEYIS--KDGLPYCEADYHAKFG 209
Query: 77 IKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLF 128
I+C C + V+ A K YH C CV C + G+E L+ ++
Sbjct: 210 IRCDSCEKYITGR--VLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
Score = 66.2 bits (160), Expect = 4e-11
Identities = 42/115 (36%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 16 LCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLY 75
LC CGN + +LRV D +H C C C L E FVR G+ C DY RLY
Sbjct: 23 LCNTCGNVCKGE-VLRVQ-DKYFHIKCFVCKACGCDLAEG-GFFVRQGEYICTLDYQRLY 79
Query: 76 GIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCR 130
G +C C F + + V+ A K YH +CF C C PGD C+
Sbjct: 80 GTRCFSCD-QFIEGE-VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQ 132
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 70.9 bits (172), Expect = 2e-12
Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYG 76
C GCG +I + L V+ D WH C KC C + L+ +DG YC+ DY +G
Sbjct: 153 CGGCGTEIKNGQAL-VALDKHWHLGCFKCKSCGKLLNAEYIS--KDGLPYCEADYHAKFG 209
Query: 77 IKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLF 128
I+C C + V+ A K YH C CV C + G+E L+ ++
Sbjct: 210 IRCDSCEKYITGR--VLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
Score = 66.2 bits (160), Expect = 4e-11
Identities = 42/115 (36%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 16 LCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLY 75
LC CGN + +LRV D +H C C C L E FVR G+ C DY RLY
Sbjct: 23 LCNTCGNVCKGE-VLRVQ-DKYFHIKCFVCKACGCDLAEG-GFFVRQGEYICTLDYQRLY 79
Query: 76 GIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCR 130
G +C C F + + V+ A K YH +CF C C PGD C+
Sbjct: 80 GTRCFSCD-QFIEGE-VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQ 132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,579,630
Number of Sequences: 37866
Number of extensions: 773758
Number of successful extensions: 3614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 321
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 2693
Number of HSP's gapped (non-prelim): 714
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.