BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|114158664 hypothetical protein LOC343505 [Homo sapiens] (421 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|114158664 hypothetical protein LOC343505 [Homo sapiens] 848 0.0 gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap... 487 e-138 gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ... 474 e-134 gi|92110019 hypothetical protein LOC55672 [Homo sapiens] 472 e-133 gi|83415174 hypothetical protein LOC400818 [Homo sapiens] 471 e-133 gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] 468 e-132 gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 467 e-132 gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 467 e-132 gi|29789405 hypothetical protein LOC284565 [Homo sapiens] 451 e-127 gi|157266285 hypothetical protein LOC728936 [Homo sapiens] 451 e-127 gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi... 449 e-126 gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ... 424 e-119 gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1... 424 e-118 gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2... 416 e-116 gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap... 416 e-116 gi|7657017 hypothetical protein LOC25832 [Homo sapiens] 335 5e-92 gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami... 127 1e-29 gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami... 125 9e-29 gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6... 125 9e-29 gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6... 123 3e-28 gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 81 2e-15 gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 57 2e-08 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 55 2e-07 gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 51 2e-06 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 2e-06 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 4e-06 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 5e-06 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 1e-05 gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 48 1e-05 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 2e-05 >gi|114158664 hypothetical protein LOC343505 [Homo sapiens] Length = 421 Score = 848 bits (2191), Expect = 0.0 Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ 60 MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ Sbjct: 1 MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ 60 Query: 61 KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH 120 KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH Sbjct: 61 KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH 120 Query: 121 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH 180 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH Sbjct: 121 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH 180 Query: 181 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS 240 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS Sbjct: 181 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS 240 Query: 241 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL Sbjct: 241 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300 Query: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS Sbjct: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360 Query: 361 EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQGSFTE 420 EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQGSFTE Sbjct: 361 EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQGSFTE 420 Query: 421 D 421 D Sbjct: 421 D 421 >gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sapiens] Length = 3815 Score = 487 bits (1253), Expect = e-138 Identities = 255/358 (71%), Positives = 290/358 (81%), Gaps = 10/358 (2%) Query: 1 MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ 60 MCL FFSPVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFRN+K+ Sbjct: 1 MCLPFFSPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKE 60 Query: 61 KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH 120 + VTQ+AGFLANQQ KYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVH Sbjct: 61 RCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVH 120 Query: 121 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH 180 +QEREL QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV Sbjct: 121 AQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQ 180 Query: 181 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS 240 KLSPEND D+DE+ + + +KVQ+S APRE QKAEEKEVPEDS EECAITYSNSHGP DS Sbjct: 181 KLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDS 240 Query: 241 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300 N PH+ KIT EEDKV+S L+ SS EW+DA++I+ EN++DDEEEE K PV P+ Sbjct: 241 NQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--- 295 Query: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 LQESEE+EV Q+S +E +T ++ SYQ TF +L EQ+VC A D+ Sbjct: 296 -----NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 348 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 397 ELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 456 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 457 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 500 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 501 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 555 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 556 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 584 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 641 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 700 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 701 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 744 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 745 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 799 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 800 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 828 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1636 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1695 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1696 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1739 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1740 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1794 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1795 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1823 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1880 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1939 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1940 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1983 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1984 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2038 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2039 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2067 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2124 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2183 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2184 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2227 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2228 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2282 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2283 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2311 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2368 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2427 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2428 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2471 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2472 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2526 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2527 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2555 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2781 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2840 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2841 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2884 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2885 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2939 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2940 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2968 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 3532 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3591 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 3592 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3635 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 3636 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3690 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 3691 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3719 Score = 62.4 bits (150), Expect = 7e-10 Identities = 54/184 (29%), Positives = 83/184 (45%), Gaps = 24/184 (13%) Query: 189 DEDENDKTKELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D DE +K +E+++ Q+ PR ++ +E EV +DSL+ C T S D P+ Sbjct: 910 DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 969 Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305 + + EE + L VD + D EEEE + P P+++ Sbjct: 970 SAVYSLEEQYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR----- 1008 Query: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNS 365 +L E E EVLQDS + +T S + S QP +F AL E+ V + DV Sbjct: 1009 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 1068 Query: 366 KGEE 369 KG++ Sbjct: 1069 KGKK 1072 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 1087 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1146 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 1147 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 1185 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 1186 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 1241 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 1256 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1315 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 1316 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 1354 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 1355 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 1410 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 1425 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1484 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 1485 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 1523 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 1524 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 1579 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 2570 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2629 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 2630 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 2668 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 2669 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 2724 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 2983 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3042 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 3043 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3081 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 3082 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3137 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 3152 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3211 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 3212 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3250 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 3251 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3306 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 3321 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3380 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 3381 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3419 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 3420 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3475 Score = 51.6 bits (122), Expect = 1e-06 Identities = 50/184 (27%), Positives = 82/184 (44%), Gaps = 11/184 (5%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 3632 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3691 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 3692 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3749 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ E+ Sbjct: 3750 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDGEY 3806 Query: 363 SNSK 366 + K Sbjct: 3807 LSMK 3810 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1980 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2039 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2040 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2097 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 2098 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2154 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2155 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2178 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 3388 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3447 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 3448 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3505 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 3506 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3562 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 3563 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3586 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 497 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 556 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 557 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 614 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 615 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 671 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 672 KYQEVEED-----------QDPSCPRLSRE---LLDEK 695 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1492 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1551 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1552 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1609 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1610 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1666 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1667 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1690 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1736 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1795 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1796 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1853 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1854 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1910 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1911 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1934 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2224 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2283 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2284 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2341 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 2342 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2398 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2399 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2422 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2637 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2696 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2697 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2754 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 2755 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2811 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2812 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2835 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 189 DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P P RE + E EV +DSL+ C T S+ DS P+ Sbjct: 1154 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1213 Query: 246 NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L ++ + + + + + E EE + P P+++ Sbjct: 1214 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 1270 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + +E EVLQDS + +T ++ QP +L EQ + A DV Sbjct: 1271 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 1328 Query: 363 SNSKGEE 369 + + EE Sbjct: 1329 KDQEEEE 1335 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 189 DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P P RE + E EV +DSL+ C T S+ DS P+ Sbjct: 1323 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1382 Query: 246 NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L ++ + + + + + E EE + P P+++ Sbjct: 1383 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 1439 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + +E EVLQDS + +T ++ QP +L EQ + A DV Sbjct: 1440 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 1497 Query: 363 SNSKGEE 369 + + EE Sbjct: 1498 KDQEEEE 1504 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 189 DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P P RE + E EV +DSL+ C T S+ DS P+ Sbjct: 3050 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3109 Query: 246 NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L ++ + + + + + E EE + P P+++ Sbjct: 3110 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 3166 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + +E EVLQDS + +T ++ QP +L EQ + A DV Sbjct: 3167 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3224 Query: 363 SNSKGEE 369 + + EE Sbjct: 3225 KDQEEEE 3231 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 189 DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P P RE + E EV +DSL+ C T S+ DS P+ Sbjct: 3219 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3278 Query: 246 NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L ++ + + + + + E EE + P P+++ Sbjct: 3279 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 3335 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + +E EVLQDS + +T ++ QP +L EQ + A DV Sbjct: 3336 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3393 Query: 363 SNSKGEE 369 + + EE Sbjct: 3394 KDQEEEE 3400 Score = 45.4 bits (106), Expect = 9e-05 Identities = 47/176 (26%), Positives = 74/176 (42%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 843 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 902 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD E + E EE + P P+++ +L + +E Sbjct: 903 QYLGLALDVD----------------EIEKYQEVEEDQDPSCPRLS-----RELLDEKEP 941 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T ++ QP +L EQ + A DV + + EE Sbjct: 942 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEE 997 >gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo sapiens] Length = 4621 Score = 474 bits (1221), Expect = e-134 Identities = 249/351 (70%), Positives = 284/351 (80%), Gaps = 10/351 (2%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFRN+K++ VTQ+ Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQL 318 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 AGFLANQQ KYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL Sbjct: 319 AGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND Sbjct: 379 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D+DE+ + + +KVQ+S APRE QKAEEKEVPEDS EECAITYSNSHGP DSN PH+ Sbjct: 439 NDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKT 498 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 KIT EEDKV+S L+ SS EW+DA++I+ EN++DDEEEE K PV P+ L Sbjct: 499 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 548 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 QESEE+EV Q+S +E +T ++ SYQ TF +L EQ+VC A D+ Sbjct: 549 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 599 Score = 414 bits (1064), Expect = e-116 Identities = 212/258 (82%), Positives = 227/258 (87%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQF N+K++ VTQ+AGFLANQQ KY Y Sbjct: 1 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SLN+HLQALLT D+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E + Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KVQ+S APRE QK EE +VPEDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240 Query: 261 VVDSESSQDEWQDALNIL 278 VVD ESS DE QDALNIL Sbjct: 241 VVDRESSHDECQDALNIL 258 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 648 ELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 708 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 751 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 752 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 806 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 892 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 951 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 952 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 995 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 996 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1050 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1051 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1079 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1136 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1195 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1196 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1239 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1240 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1294 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1295 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1323 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1380 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1439 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1440 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1483 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1484 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1538 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1539 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1567 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1624 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1683 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1684 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1727 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1728 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1782 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1783 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1811 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1868 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1927 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1928 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1971 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1972 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2026 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2027 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2055 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2112 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2171 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2172 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2215 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2216 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2270 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2271 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2299 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2356 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2415 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2416 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2459 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2460 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2514 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2515 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2543 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2600 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2659 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2660 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2703 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2704 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2758 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2759 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2787 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 3351 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3410 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 3411 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3454 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 3455 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3509 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 3510 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3538 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 3595 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3654 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 3655 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3698 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 3699 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3753 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 3754 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3782 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 3839 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3898 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 3899 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3942 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 3943 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3997 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 3998 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 4026 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 4083 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 4142 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 4143 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 4186 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 4187 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 4241 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 4242 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 4270 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 4327 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 4386 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 4387 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 4430 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 4431 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 4485 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 4486 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 4514 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 2802 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2861 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 2862 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 2900 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 2901 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 2956 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 2971 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3030 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 3031 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3069 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 3070 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3125 Score = 57.8 bits (138), Expect = 2e-08 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +E EV +DSL+ C T S D P+ + + EE Sbjct: 3140 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3199 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + L VD + D EEEE + P P+++ +L E E Sbjct: 3200 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3238 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T S + S QP +F AL E+ V + DV KG++ Sbjct: 3239 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3294 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 748 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 865 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 866 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 922 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 923 KYQEVEED-----------QDPSCPRLSRE---LLDEK 946 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1236 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1353 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1354 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1410 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1411 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1434 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1724 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1783 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1784 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1841 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1842 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1898 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1899 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1922 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1968 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2027 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2028 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2085 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 2086 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2142 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2143 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2166 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2212 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2271 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2272 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2329 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 2330 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2386 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2387 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2410 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2456 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2515 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2516 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2573 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 2574 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2630 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2631 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2654 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 3939 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3998 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 3999 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRLSR-- 4056 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 4057 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 4113 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 4114 KYQEVEED-----------QDPSCPRLSRE---LLDEK 4137 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 992 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1109 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1110 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1166 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1167 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1190 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1480 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1539 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1540 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1597 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1598 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1654 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1655 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1678 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 3207 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3266 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 3267 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3324 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 3325 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3381 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 3382 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3405 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 3451 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3510 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 3511 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3568 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 3569 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3625 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 3626 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3649 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 3695 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3754 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 3755 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3812 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 3813 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3869 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 3870 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3893 Score = 49.7 bits (117), Expect = 5e-06 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 4183 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 4242 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 4243 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 4300 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 4301 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 4357 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 4358 KYQEVEED-----------QDPSCPRLSRE---LLDEK 4381 Score = 47.4 bits (111), Expect = 2e-05 Identities = 49/173 (28%), Positives = 75/173 (43%), Gaps = 11/173 (6%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 4427 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 4486 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P++ Sbjct: 4487 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLN--- 4543 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355 G+ L E EE EVLQDS + +T ++ S+Q F + EQ + A Sbjct: 4544 -GV-LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 4594 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 189 DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P P RE + E EV +DSL+ C T S+ DS P+ Sbjct: 2869 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2928 Query: 246 NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L ++ + + + + + E EE + P P+++ Sbjct: 2929 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 2985 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + +E EVLQDS + +T ++ QP +L EQ + A DV Sbjct: 2986 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3043 Query: 363 SNSKGEE 369 + + EE Sbjct: 3044 KDQEEEE 3050 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%) Query: 189 DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P P RE + E EV +DSL+ C T S+ DS P+ Sbjct: 3038 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3097 Query: 246 NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L ++ + + + + + E EE + P P+++ Sbjct: 3098 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 3154 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + +E EVLQDS + +T ++ QP +L EQ + A DV Sbjct: 3155 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3212 Query: 363 SNSKGEE 369 + + EE Sbjct: 3213 KDQEEEE 3219 >gi|92110019 hypothetical protein LOC55672 [Homo sapiens] Length = 1214 Score = 472 bits (1214), Expect = e-133 Identities = 250/351 (71%), Positives = 283/351 (80%), Gaps = 10/351 (2%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILE+NEKLRPQLAE KQQFRN+K+K VTQ+ Sbjct: 530 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQL 589 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 A FLANQQNKYKYEECKDLIKS+LR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL Sbjct: 590 ACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 649 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QLREKLREGRDAS SLNQHLQALLTPD+ D SQGQD +EQLAEGCRLA+ L KLSPEND Sbjct: 650 QLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPEND 709 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D DE+ + + +KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+ Sbjct: 710 NDHDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKT 769 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 KIT EEDKV+S L+ SS EW+DA++I+ EN++DDEEEE K PV P+ L Sbjct: 770 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 819 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 QESEE+EV Q+S +E +T ++ SYQ GTF +L EQ+VC A D+ Sbjct: 820 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDI 870 Score = 440 bits (1131), Expect = e-123 Identities = 226/271 (83%), Positives = 241/271 (88%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILE+NEKLRPQLAE KQQFRN+K+K VTQ+ Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQL 318 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 AGFLANQQNKYKYEEC+DLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL Sbjct: 319 AGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 378 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QLREKLREGRDAS SLNQHLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND Sbjct: 379 QLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 DEDE+ + +E +KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNI Sbjct: 439 EDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNI 498 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNIL 278 IT EEDKVNS LVVD ESS DE QDA+NIL Sbjct: 499 NITFEEDKVNSALVVDRESSHDECQDAVNIL 529 Score = 420 bits (1079), Expect = e-117 Identities = 215/258 (83%), Positives = 228/258 (88%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGPWSSEKAE NILEINEKLRPQLAENKQQFRN+K+K VTQ+AGFLAN+Q KYKY Sbjct: 1 MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SLNQHLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E + Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNI IT EEDKVNS L Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240 Query: 261 VVDSESSQDEWQDALNIL 278 VVD ESS DE QDA+NIL Sbjct: 241 VVDRESSHDECQDAVNIL 258 Score = 61.2 bits (147), Expect = 2e-09 Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 919 ELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 978 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+++ + EE + L VD Sbjct: 979 QDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD----------------R 1022 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E+ E EVLQDS + +T S + S P Sbjct: 1023 IKKDQEEEEDQGPPCPRLS-----RELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPY 1077 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1078 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1106 Score = 50.4 bits (119), Expect = 3e-06 Identities = 55/193 (28%), Positives = 81/193 (41%), Gaps = 12/193 (6%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E +A E EV +DSL+ C T S+ DS P+ Sbjct: 1019 DVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYG 1078 Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILL----ENQNDDEEEEGKAPVPPQVTLW 301 + EE V L V + + + + E EE + P P+++ Sbjct: 1079 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLS-- 1136 Query: 302 ICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASE 361 G+ L E EE EVLQDS + +T ++ S+Q F + EQ + A DV + Sbjct: 1137 --GM-LMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNR 1193 Query: 362 HSNSKGEETPLGF 374 G L F Sbjct: 1194 FLTLMGTSLHLVF 1206 >gi|83415174 hypothetical protein LOC400818 [Homo sapiens] Length = 942 Score = 471 bits (1211), Expect = e-133 Identities = 248/351 (70%), Positives = 285/351 (81%), Gaps = 10/351 (2%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K +TQ+ Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 AGFLANQQNKYKYEECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL Sbjct: 319 AGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND Sbjct: 379 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D++E+ + + +KVQ+S APRE QKAEEKEVPEDSLEECAITYSNSHGP DSN PH+ Sbjct: 439 NDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKT 498 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 KIT EEDKV+S L+ SS E +DA++I+ EN++DDEEEE K PV P+ L Sbjct: 499 KITFEEDKVDSTLI--GSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR--------NL 548 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 QESEE+EV Q+S +E +T ++ SY+ TF +L EQ+VC A D+ Sbjct: 549 QESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDI 599 Score = 415 bits (1067), Expect = e-116 Identities = 212/258 (82%), Positives = 229/258 (88%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQF N+K++ +TQ+AGFLAN+Q KYKY Sbjct: 1 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QL+EKLREGRDAS Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E + Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KV ESPAPRE QKAEE +V EDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240 Query: 261 VVDSESSQDEWQDALNIL 278 VVD ESS DE QDALNIL Sbjct: 241 VVDRESSHDECQDALNIL 258 Score = 57.8 bits (138), Expect = 2e-08 Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 648 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL T S D P+ + + EE + L +D Sbjct: 708 QDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLD----------------R 751 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S+QP Sbjct: 752 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPY 806 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835 Score = 45.1 bits (105), Expect = 1e-04 Identities = 49/173 (28%), Positives = 75/173 (43%), Gaps = 11/173 (6%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 748 DLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYG 807 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P++ Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLN--- 864 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355 G+ L E EE EVLQDS + +T ++ S+Q F + EQ + A Sbjct: 865 -GV-LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915 >gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] Length = 3628 Score = 468 bits (1204), Expect = e-132 Identities = 246/351 (70%), Positives = 283/351 (80%), Gaps = 10/351 (2%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K +TQ+ Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 +GFLANQQ KYKYEECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL Sbjct: 319 SGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QL+EKLREGRDAS SLN+HLQALLTP + D SQGQD +EQLAEGCRLA+HLV KLSPEND Sbjct: 379 QLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D+DE+ + + +KVQ+S APRE QKAEEKEVPEDSLEECAITYSNSHG DSN PH+ Sbjct: 439 NDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKT 498 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 KIT EEDKV+S L+ SS EW+DA++I+ EN++DDEEEE K PV P+ L Sbjct: 499 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 548 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 QESEE+EV Q+S +E +T ++ SYQ TF +L EQ+VC A D+ Sbjct: 549 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 599 Score = 414 bits (1063), Expect = e-115 Identities = 212/258 (82%), Positives = 227/258 (87%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGPWSSEKAEMNILEINE LRPQLAE KQQFRN+K+K +TQ+AGFLAN+Q KYKY Sbjct: 1 MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SL +HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E + Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240 Query: 261 VVDSESSQDEWQDALNIL 278 VVD ESS DE QDALNIL Sbjct: 241 VVDRESSHDECQDALNIL 258 Score = 63.2 bits (152), Expect = 4e-10 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2602 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2661 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2662 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2705 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2706 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2789 Score = 63.2 bits (152), Expect = 4e-10 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2846 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2905 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2906 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2949 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2950 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3004 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 3005 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3033 Score = 62.8 bits (151), Expect = 6e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 892 ELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 951 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 952 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 995 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 996 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1050 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1051 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1079 Score = 62.8 bits (151), Expect = 6e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1626 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1685 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1686 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1729 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1730 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1784 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E V + DV KG++ Sbjct: 1785 GSSFYALEENHVGFSLDVGEIEKKGKGKK 1813 Score = 62.8 bits (151), Expect = 6e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1870 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1929 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1930 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1973 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1974 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2028 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E V + DV KG++ Sbjct: 2029 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2057 Score = 62.8 bits (151), Expect = 6e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2114 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2173 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2174 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2217 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2218 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2272 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E V + DV KG++ Sbjct: 2273 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2301 Score = 62.8 bits (151), Expect = 6e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 2358 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2417 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 2418 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2461 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 2462 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2516 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E V + DV KG++ Sbjct: 2517 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2545 Score = 62.4 bits (150), Expect = 7e-10 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 3165 ELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3224 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 3225 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3268 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 3269 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3323 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 3324 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3352 Score = 62.0 bits (149), Expect = 1e-09 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 648 ELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 708 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 751 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 752 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 806 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835 Score = 61.2 bits (147), Expect = 2e-09 Identities = 56/209 (26%), Positives = 92/209 (44%), Gaps = 25/209 (11%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1380 ELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1439 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL C T S D P+ + + EE + L VD ++ Sbjct: 1440 QDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR--------------IK 1485 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 ++EE+E + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 1486 KDQEEEEDEDQDPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1540 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E V + DV KG++ Sbjct: 1541 GSSFYALEENHVGFSLDVGEIEKKGKGKK 1569 Score = 60.5 bits (145), Expect = 3e-09 Identities = 57/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 1136 ELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1195 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD Sbjct: 1196 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1239 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D+EEEE + P P+++ +L E EVLQDS + +T S + S QP Sbjct: 1240 IKKDEEEEEDQDPPCPRLSR-----ELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1294 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 1295 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1323 Score = 53.5 bits (127), Expect = 3e-07 Identities = 59/220 (26%), Positives = 96/220 (43%), Gaps = 25/220 (11%) Query: 187 DTDEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPP 243 D D + D+ +E D+ Q+ P PR E + E EV +DSL+ C T S+ DS P Sbjct: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539 Query: 244 HKNIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300 + + EE+ V L V + + + + + + E EE + P P+++ Sbjct: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599 Query: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360 +L + + EVLQDS + +T +++ S QP F L +Q V A D+ Sbjct: 1600 -----ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDE 1654 Query: 361 EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1655 IEKYQEVEED-----------QDPSCPRLSRE---LLDEK 1680 Score = 53.1 bits (126), Expect = 5e-07 Identities = 49/195 (25%), Positives = 87/195 (44%), Gaps = 8/195 (4%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L ++ D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 3409 ELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3468 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S D P+ + + EE + L VD + + + + Sbjct: 3469 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSK 3528 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + +EG+ P + G+ L E EE+EVLQDS + +T ++ S+Q Sbjct: 3529 KERRRGRKEGEEDQNPPCPR-LNGV-LMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHY 3586 Query: 341 EGTFLALVEQKVCSA 355 F + EQ + A Sbjct: 3587 RSVFYSFEEQHISFA 3601 Score = 50.8 bits (120), Expect = 2e-06 Identities = 55/209 (26%), Positives = 92/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPR-EEQKAEEK--EVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR + +EK EV Sbjct: 3090 ELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVL 3149 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S DS P+++ E+ +V L VD + E Sbjct: 3150 QDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVG--LAVDMD--------------E 3193 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + E EE + P P+++ +L + +E EVLQDS + +T ++ QP Sbjct: 3194 IEKYQEVEEDQDPSCPRLS-----RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 3248 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +L EQ + A DV + + EE Sbjct: 3249 SSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277 Score = 49.3 bits (116), Expect = 7e-06 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q+ P PR ++ E PE DSL+ C T S+ DS P+ Sbjct: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1353 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1354 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIE 1410 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1411 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1434 Score = 48.5 bits (114), Expect = 1e-05 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 748 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 865 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 866 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIE 922 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 923 KYQEVEED-----------QDPSCPRLSRE---LLDEK 946 Score = 48.5 bits (114), Expect = 1e-05 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 992 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1109 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q+V A D+ Sbjct: 1110 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIE 1166 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1167 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1190 Score = 48.1 bits (113), Expect = 1e-05 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE+ V L V + + + + + + E EE + P P+++ Sbjct: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1843 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q V A D+ Sbjct: 1844 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 1900 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 1901 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1924 Score = 48.1 bits (113), Expect = 1e-05 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE+ V L V + + + + + + E EE + P P+++ Sbjct: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2087 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q V A D+ Sbjct: 2088 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2144 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2145 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2168 Score = 48.1 bits (113), Expect = 1e-05 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE+ V L V + + + + + + E EE + P P+++ Sbjct: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2331 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q V A D+ Sbjct: 2332 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2388 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2389 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2412 Score = 48.1 bits (113), Expect = 1e-05 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE+ V L V + + + + + + E EE + P P+++ Sbjct: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2575 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q V A D+ Sbjct: 2576 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2632 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2633 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2656 Score = 47.4 bits (111), Expect = 2e-05 Identities = 58/218 (26%), Positives = 92/218 (42%), Gaps = 25/218 (11%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P+++ Sbjct: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2819 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +L + + EVLQDS + +T +++ S QP F L +Q V A D+ Sbjct: 2820 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2876 Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400 + EE +D R+S++ LLDEK Sbjct: 2877 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2900 Score = 46.2 bits (108), Expect = 6e-05 Identities = 54/207 (26%), Positives = 89/207 (42%), Gaps = 38/207 (18%) Query: 197 KELDKVQESPAPREEQKAEEKEVP---EDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +++ P +DSL+ C T S DS P+++ E+ Sbjct: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 +V L VD + E + E EE + P P+++ +L + + Sbjct: 3108 QRVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSR-----ELLDEKGP 3146 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLG 373 EVLQDS + +T ++ S QP F L +Q+V A D+ + EE Sbjct: 3147 EVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEED--- 3203 Query: 374 FPDTKYCWKDEKDERMSQKVAFLLDEK 400 +D R+S++ LLDEK Sbjct: 3204 --------QDPSCPRLSRE---LLDEK 3219 Score = 45.8 bits (107), Expect = 7e-05 Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 24/176 (13%) Query: 197 KELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +++ PE DSL+ C T S DS P+++ E+ Sbjct: 3367 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3426 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 V L VD + E + E EE + P P+++ +L + +E Sbjct: 3427 QHVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSR-----ELLDEKEP 3465 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T ++ QP +L EQ + A DV KG++ Sbjct: 3466 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKK 3521 Score = 35.4 bits (80), Expect = 0.098 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 197 KELDKVQESPAPREE---QKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR + EE+EV +DSL+ C T S DS ++++ + EE Sbjct: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595 Query: 254 DKVNSILVVDS 264 ++ L VD+ Sbjct: 3596 QHISFALYVDN 3606 >gi|156071420 hypothetical protein LOC728912 [Homo sapiens] Length = 790 Score = 467 bits (1202), Expect = e-132 Identities = 255/385 (66%), Positives = 292/385 (75%), Gaps = 11/385 (2%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFR++K+K VTQ+ Sbjct: 184 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQV 243 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 A FLA QQNKYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL Sbjct: 244 ACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 303 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND Sbjct: 304 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 363 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D+DE+ + + +KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+ Sbjct: 364 NDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKT 423 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 KIT EEDKV+S L+ SS EW+DA++I+ EN++DDEEEE K PV P+ L Sbjct: 424 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 473 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSK 366 QESEE+EV Q+S +E +T + SYQ TF +L EQ+VC A D+ K Sbjct: 474 QESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVK 533 Query: 367 GEETPLGFPDTKYCWKDEKDERMSQ 391 E+ P DEK+ + Q Sbjct: 534 KEDQEATGPRLSRELLDEKEPEVLQ 558 Score = 258 bits (660), Expect = 5e-69 Identities = 133/169 (78%), Positives = 145/169 (85%) Query: 110 EELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLA 169 +E++QYKVLVHSQEREL QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLA Sbjct: 15 QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74 Query: 170 EGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAI 229 EGCRLA+HLV KLSPEND DEDE+ + +E +KV ES APRE QKAEE +VPEDSLEECAI Sbjct: 75 EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134 Query: 230 TYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNIL 278 T SNSHGP DS PHKNIKIT EEDKVNS LVVD ESS D QDALNIL Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNIL 183 Score = 47.0 bits (110), Expect = 3e-05 Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 27/158 (17%) Query: 168 LAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAP---REEQKAEEKEVPE 221 L + C+ R + L + D DE +K +E+++ Q+ P RE +E EV + Sbjct: 574 LTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQ 633 Query: 222 DSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLEN 281 DSL+ C T S D P+++ + EE + L VD Sbjct: 634 DSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD----------------RI 677 Query: 282 QNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDS 319 + D EEEE + P P+++ +L E E EVLQDS Sbjct: 678 KKDQEEEEDQGPPCPRLS-----RELLEVVEPEVLQDS 710 Score = 45.4 bits (106), Expect = 9e-05 Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 22/177 (12%) Query: 194 DKTKELDKVQESPA-PREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSE 252 D+ K+ D+ P RE +E EV +DSL+ C T S G +DS P+++ E Sbjct: 530 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLE 589 Query: 253 EDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEE 312 + ++ L VD + E + E EE + P P+++ +L +E Sbjct: 590 QQRIG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLS-----RELLAEKE 628 Query: 313 KEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T ++ QP +L EQ + A DV + + EE Sbjct: 629 PEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 685 >gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo sapiens] Length = 790 Score = 467 bits (1202), Expect = e-132 Identities = 255/385 (66%), Positives = 292/385 (75%), Gaps = 11/385 (2%) Query: 8 PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67 PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFR++K+K VTQ+ Sbjct: 184 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQV 243 Query: 68 AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127 A FLA QQNKYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL Sbjct: 244 ACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 303 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND Sbjct: 304 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 363 Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D+DE+ + + +KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+ Sbjct: 364 NDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKT 423 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 KIT EEDKV+S L+ SS EW+DA++I+ EN++DDEEEE K PV P+ L Sbjct: 424 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 473 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSK 366 QESEE+EV Q+S +E +T + SYQ TF +L EQ+VC A D+ K Sbjct: 474 QESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVK 533 Query: 367 GEETPLGFPDTKYCWKDEKDERMSQ 391 E+ P DEK+ + Q Sbjct: 534 KEDQEATGPRLSRELLDEKEPEVLQ 558 Score = 259 bits (663), Expect = 2e-69 Identities = 134/169 (79%), Positives = 145/169 (85%) Query: 110 EELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLA 169 EE++QYKVLVHSQEREL QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLA Sbjct: 15 EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74 Query: 170 EGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAI 229 EGCRLA+HLV KLSPEND DEDE+ + +E +KV ES APRE QKAEE +VPEDSLEECAI Sbjct: 75 EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134 Query: 230 TYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNIL 278 T SNSHGP DS PHKNIKIT EEDKVNS LVVD ESS D QDALNIL Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNIL 183 Score = 47.0 bits (110), Expect = 3e-05 Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 27/158 (17%) Query: 168 LAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAP---REEQKAEEKEVPE 221 L + C+ R + L + D DE +K +E+++ Q+ P RE +E EV + Sbjct: 574 LTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQ 633 Query: 222 DSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLEN 281 DSL+ C T S D P+++ + EE + L VD Sbjct: 634 DSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD----------------RI 677 Query: 282 QNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDS 319 + D EEEE + P P+++ +L E E EVLQDS Sbjct: 678 KKDQEEEEDQGPPCPRLS-----RELLEVVEPEVLQDS 710 Score = 45.4 bits (106), Expect = 9e-05 Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 22/177 (12%) Query: 194 DKTKELDKVQESPA-PREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSE 252 D+ K+ D+ P RE +E EV +DSL+ C T S G +DS P+++ E Sbjct: 530 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLE 589 Query: 253 EDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEE 312 + ++ L VD + E + E EE + P P+++ +L +E Sbjct: 590 QQRIG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLS-----RELLAEKE 628 Query: 313 KEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369 EVLQDS + +T ++ QP +L EQ + A DV + + EE Sbjct: 629 PEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 685 >gi|29789405 hypothetical protein LOC284565 [Homo sapiens] Length = 670 Score = 451 bits (1159), Expect = e-127 Identities = 244/372 (65%), Positives = 281/372 (75%), Gaps = 11/372 (2%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K +TQ+AGFLAN+Q KYKY Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SLN+HLQALLTPD+ D SQGQD +EQLAEGCRL +HLV KLSPEND D+DE+ + + + Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PHK KIT EEDKV+S L Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240 Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320 + SS EW+DA++I+ EN++DDEEEE K PV P+ LQESEE+EV Q+S Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESW 290 Query: 321 EERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSKGEETPLGFPDTKY 379 +E +T ++ SYQ TF +L EQ+VC A D+ K E+ P Sbjct: 291 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 350 Query: 380 CWKDEKDERMSQ 391 DEK+ + Q Sbjct: 351 ELLDEKEPEVLQ 362 Score = 63.9 bits (154), Expect = 3e-10 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 377 ELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 436 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S+ D P+ + + EE + L VD Sbjct: 437 QDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVD----------------R 480 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 481 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 564 Score = 46.6 bits (109), Expect = 4e-05 Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 6/168 (3%) Query: 191 DENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247 D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ + Sbjct: 479 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538 Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307 EE V L V + + + + + +EG+ PP L+ G+ L Sbjct: 539 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLY--GV-L 595 Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355 E EE EVLQDS + +T + S+Q F + E+ + A Sbjct: 596 MEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFA 643 Score = 31.2 bits (69), Expect = 1.8 Identities = 17/52 (32%), Positives = 29/52 (55%) Query: 213 KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDS 264 + EE EV +DSL+ C T S DS ++++ + EE+ ++ L VD+ Sbjct: 597 EVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDN 648 >gi|157266285 hypothetical protein LOC728936 [Homo sapiens] Length = 670 Score = 451 bits (1159), Expect = e-127 Identities = 244/372 (65%), Positives = 281/372 (75%), Gaps = 11/372 (2%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K +TQ+AGFLAN+Q KYKY Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS Sbjct: 61 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SLN+HLQALLTPD+ D SQGQD +EQLAEGCRL +HLV KLSPEND D+DE+ + + + Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PHK KIT EEDKV+S L Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240 Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320 + SS EW+DA++I+ EN++DDEEEE K PV P+ LQESEE+EV Q+S Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESW 290 Query: 321 EERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSKGEETPLGFPDTKY 379 +E +T ++ SYQ TF +L EQ+VC A D+ K E+ P Sbjct: 291 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 350 Query: 380 CWKDEKDERMSQ 391 DEK+ + Q Sbjct: 351 ELLDEKEPEVLQ 362 Score = 62.8 bits (151), Expect = 6e-10 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 377 ELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 436 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL+ C T S+ D P+ + + EE + L VD Sbjct: 437 QDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 480 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 481 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 564 Score = 48.1 bits (113), Expect = 1e-05 Identities = 47/170 (27%), Positives = 71/170 (41%), Gaps = 6/170 (3%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 477 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536 Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305 + EE V L V + + + + + +EG+ PP L Sbjct: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRL---NG 593 Query: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355 L E EE EVLQDS + +T ++ S+Q F + E+ + A Sbjct: 594 VLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFA 643 Score = 32.0 bits (71), Expect = 1.1 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Query: 206 PAPREE---QKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVV 262 P PR + EE EV +DSL+ C T S DS ++++ + EE+ ++ L V Sbjct: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646 Query: 263 DS 264 D+ Sbjct: 647 DN 648 >gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapiens] Length = 633 Score = 449 bits (1156), Expect = e-126 Identities = 248/384 (64%), Positives = 287/384 (74%), Gaps = 11/384 (2%) Query: 9 VPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMA 68 VPG TSSATNV+MVVSAGPWS EKAEMNILEIN+K RPQLAENKQQFRN+KQK LVTQ+A Sbjct: 45 VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVA 104 Query: 69 GFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQ 128 FLAN+QN Y YE+CKDLIKSMLR+E EEKLAE+L QAEELRQYKVLVHSQEREL Q Sbjct: 105 YFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQ 164 Query: 129 LREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDT 188 LREKL+EGRDAS SLNQHLQALLTPD+ DNSQG+D REQLAEGCRLA+HLV KLSPEND Sbjct: 165 LREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD 224 Query: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248 DEDE+ K +E +KVQE APRE QKAEEKEVPEDSLEECAIT SNSH P +SN P+ N + Sbjct: 225 DEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTR 284 Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308 IT EED+V+S L+ SS DEW DA+ I+ EN++D E+EE K PV P+ LQ Sbjct: 285 ITFEEDQVDSTLI--DSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR--------NLQ 334 Query: 309 ESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNS-KG 367 ESEE+E Q+S +E T D+S SYQ TF ++ EQ+V A D+ + K Sbjct: 335 ESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKK 394 Query: 368 EETPLGFPDTKYCWKDEKDERMSQ 391 E+ P DEK+ + Q Sbjct: 395 EDQEATSPRLSRELLDEKEPEVLQ 418 Score = 48.9 bits (115), Expect = 9e-06 Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 24/173 (13%) Query: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPS---DSNPPHK 245 D D K +E ++ Q P PR ++ E PED + YS DS P+ Sbjct: 458 DLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYG 517 Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305 + + EE+ V L VD +E + EE++ K P P + Sbjct: 518 SCFYSLEEEHVGFSLDVDE--------------IEKYQEGEEDQ-KPPCPRLNEV----- 557 Query: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 L E+EE EVLQDS + +T+ + + S+Q F + EQ V A DV Sbjct: 558 -LMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 6/104 (5%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVP 220 +L + C+ + L E+ D DE +K +E ++ Q+ P PR + +AEE EV Sbjct: 508 ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDS 264 +DSL+ C T S S +++ + EE V+ L VD+ Sbjct: 568 QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDN 611 >gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9 [Homo sapiens] Length = 299 Score = 424 bits (1091), Expect = e-119 Identities = 216/280 (77%), Positives = 243/280 (86%), Gaps = 2/280 (0%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFR++K+K VTQ+AGFLA QQNKYKY Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 EECKDLIKSMLR ELQFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS Sbjct: 61 EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120 Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200 SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND D+DE+ + + + Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260 KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+ KIT EEDKV+S L Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240 Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300 + SS EW+DA++I+ EN++DDEEEE K PV P+ ++ Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSV 278 >gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1 [Homo sapiens] Length = 667 Score = 424 bits (1089), Expect = e-118 Identities = 242/402 (60%), Positives = 290/402 (72%), Gaps = 16/402 (3%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ + LANQ KYK Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EE KD+I S+LR+ELQ EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA Sbjct: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197 S LN+HL+ LLTPD D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+ DK + Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257 E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+ Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317 S LVV+SE DE ++ALNI ENQND EEEEGKAPVPP+ + E E L+ Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR------NRQSLEPGELTNLR 293 Query: 318 D---SPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGF 374 D SP + HD S SY+ E +FLAL EQKVCSAQDVA ++SN K +ET LGF Sbjct: 294 DFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGF 353 Query: 375 PDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416 + + D ++ + + VA L IP +L G Sbjct: 354 LEKQ---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 392 Score = 68.6 bits (166), Expect = 1e-11 Identities = 55/172 (31%), Positives = 89/172 (51%), Gaps = 27/172 (15%) Query: 194 DKTKELDKV--QESPAPREEQ---KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248 +K +L++V QE+ APR + + ++ E+P++SL+ C +T S + S P+ + Sbjct: 355 EKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWST- 413 Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308 + S EDK S+ +VD + + D EE E ++P P+++ +L Sbjct: 414 LYSFEDKQVSLALVD----------------KIKKDQEEIEDQSPPCPRLSQ-----ELP 452 Query: 309 ESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360 E +E+EV +DS E T HDVS +QP T +L +Q CSA DVAS Sbjct: 453 EVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVAS 504 >gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2 [Homo sapiens] Length = 638 Score = 416 bits (1069), Expect = e-116 Identities = 236/399 (59%), Positives = 281/399 (70%), Gaps = 39/399 (9%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ + LANQ KYK Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EE KD+I S+LR+ELQ EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA Sbjct: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197 S LN+HL+ LLTPD D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+ DK + Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257 E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+ Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317 S LVV+SE DE ++ALNI ENQND EEEEGKAPVPP+ Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-------------------- 279 Query: 318 DSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDT 377 HD S SY+ E +FLAL EQKVCSAQDVA ++SN K +ET LGF + Sbjct: 280 ------------HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEK 327 Query: 378 KYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416 + D ++ + + VA L IP +L G Sbjct: 328 Q---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 363 Score = 69.7 bits (169), Expect = 5e-12 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 39/253 (15%) Query: 120 HSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFRE---------QLAE 170 H +E E + + + + + +A + P HD S RE ++ Sbjct: 250 HDEEEEALNIPPENQNDHEEEEG-----KAPVPPRHHDKSNSYRHREVSFLALDEQKVCS 304 Query: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVPEDSLEEC 227 +AR + E E E K QE+ APR + + ++ E+P++SL+ C Sbjct: 305 AQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGC 364 Query: 228 AITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEE 287 +T S + S P+ + + S EDK S+ +VD + + D EE Sbjct: 365 CLTPSILPDLTPSYHPYWST-LYSFEDKQVSLALVD----------------KIKKDQEE 407 Query: 288 EEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLAL 347 E ++P P+++ +L E +E+EV +DS E T HDVS +QP T +L Sbjct: 408 IEDQSPPCPRLSQ-----ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSL 462 Query: 348 VEQKVCSAQDVAS 360 +Q CSA DVAS Sbjct: 463 EDQLACSALDVAS 475 >gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sapiens] Length = 638 Score = 416 bits (1069), Expect = e-116 Identities = 236/399 (59%), Positives = 281/399 (70%), Gaps = 39/399 (9%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ + LANQ KYK Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EE KD+I S+LR+ELQ EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA Sbjct: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197 S LN+HL+ LLTPD D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+ DK + Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257 E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+ Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317 S LVV+SE DE ++ALNI ENQND EEEEGKAPVPP+ Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-------------------- 279 Query: 318 DSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDT 377 HD S SY+ E +FLAL EQKVCSAQDVA ++SN K +ET LGF + Sbjct: 280 ------------HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEK 327 Query: 378 KYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416 + D ++ + + VA L IP +L G Sbjct: 328 Q---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 363 Score = 69.7 bits (169), Expect = 5e-12 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 39/253 (15%) Query: 120 HSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFRE---------QLAE 170 H +E E + + + + + +A + P HD S RE ++ Sbjct: 250 HDEEEEALNIPPENQNDHEEEEG-----KAPVPPRHHDKSNSYRHREVSFLALDEQKVCS 304 Query: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVPEDSLEEC 227 +AR + E E E K QE+ APR + + ++ E+P++SL+ C Sbjct: 305 AQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGC 364 Query: 228 AITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEE 287 +T S + S P+ + + S EDK S+ +VD + + D EE Sbjct: 365 CLTPSILPDLTPSYHPYWST-LYSFEDKQVSLALVD----------------KIKKDQEE 407 Query: 288 EEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLAL 347 E ++P P+++ +L E +E+EV +DS E T HDVS +QP T +L Sbjct: 408 IEDQSPPCPRLSQ-----ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSL 462 Query: 348 VEQKVCSAQDVAS 360 +Q CSA DVAS Sbjct: 463 EDQLACSALDVAS 475 >gi|7657017 hypothetical protein LOC25832 [Homo sapiens] Length = 921 Score = 335 bits (859), Expect = 5e-92 Identities = 178/269 (66%), Positives = 209/269 (77%), Gaps = 10/269 (3%) Query: 90 MLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQA 149 MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS SLN+HLQA Sbjct: 1 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60 Query: 150 LLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPR 209 LLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND D+DE+ + + +KVQ+S APR Sbjct: 61 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120 Query: 210 EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQD 269 E QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+ KIT EEDKV+S L+ SS Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178 Query: 270 EWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCS 329 EW+DA++I+ EN++DDEEEE K PV P+ LQESEE+EV Q+S +E +T Sbjct: 179 EWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESWDEGYSTLSI 230 Query: 330 DHDVSQSYQPCEGTFLALVEQKVCSAQDV 358 ++ SY+ TF +L EQ+VC A D+ Sbjct: 231 PPEMLASYKSYSSTFHSLEEQQVCMAVDI 259 Score = 60.8 bits (146), Expect = 2e-09 Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR ++ +E EV Sbjct: 627 ELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 686 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL C T S D P+ + + EE + L VD Sbjct: 687 QDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 730 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 731 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 785 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 786 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 814 Score = 59.3 bits (142), Expect = 6e-09 Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220 +L + C+ R + L + + DE +K +E+++ Q+ PR ++ +E EV Sbjct: 308 ELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 367 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 +DSL C T S D P+ + + EE + L VD Sbjct: 368 QDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 411 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + D EEEE + P P+++ +L E E EVLQDS + +T S + S QP Sbjct: 412 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 466 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +F AL E+ V + DV KG++ Sbjct: 467 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 495 Score = 49.3 bits (116), Expect = 7e-06 Identities = 54/209 (25%), Positives = 91/209 (43%), Gaps = 27/209 (12%) Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPR---EEQKAEEKEVP 220 +L + C+ R + L + D DE +K +E+++ Q+ PR E +E EV Sbjct: 552 ELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVL 611 Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280 ++SL+ C T S +DS P+++ E+ +V L VD + E Sbjct: 612 QESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVG--LAVDMD--------------E 655 Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340 + E EE + P P+++ +L + +E EVLQDS +T ++ QP Sbjct: 656 IEKYQEVEEDQDPSCPRLS-----RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPY 710 Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369 +L EQ + A DV + + EE Sbjct: 711 SSAVYSLEEQYLGLALDVDRIKKDQEEEE 739 Score = 48.9 bits (115), Expect = 9e-06 Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 38/207 (18%) Query: 197 KELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR ++ +++ PE DSL+ C T S +DS P+++ E+ Sbjct: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 +V L VD + E + E EE + P P+++ +L + +E Sbjct: 570 QRVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSG-----ELLDEKEP 608 Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLG 373 EVLQ+S + +T +++ S QP F L +Q+V A D+ + EE Sbjct: 609 EVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEED--- 665 Query: 374 FPDTKYCWKDEKDERMSQKVAFLLDEK 400 +D R+S++ LLDEK Sbjct: 666 --------QDPSCPRLSRE---LLDEK 681 Score = 44.7 bits (104), Expect = 2e-04 Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 11/173 (6%) Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245 D D K +E ++ Q P PR E + E EV +DSL+ C T S+ DS P+ Sbjct: 727 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 786 Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302 + EE V L V + + + + + + E EE + P P++ Sbjct: 787 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSM- 845 Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355 L E EE EVLQDS + +T ++ S+Q F + E+ + A Sbjct: 846 ----LMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFA 894 Score = 33.9 bits (76), Expect = 0.28 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 197 KELDKVQESPAPREEQ---KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 KE ++ Q P PR + EE EV +DSL+ C T S DS ++++ + EE Sbjct: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888 Query: 254 DKVNSILVVDS 264 + ++ L VD+ Sbjct: 889 EHISFALYVDN 899 >gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 298 Score = 127 bits (320), Expect = 1e-29 Identities = 79/199 (39%), Positives = 112/199 (56%), Gaps = 15/199 (7%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 M VSA +AEM+ILE N+ LR +L + KQ F+++ +KFL ++ + L N KYK Sbjct: 1 MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EECKDLI+S+L EE+QF+E +LAE + A LR + L+ +Q EL LR+K++EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120 Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192 + QH+ + LL Q Q F EQ+ +G +L LV KL+ EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180 Query: 193 NDKTKELDKVQESPAPREE 211 D+ K L APR E Sbjct: 181 EDRQKPL-------APRSE 192 >gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 298 Score = 125 bits (313), Expect = 9e-29 Identities = 78/199 (39%), Positives = 111/199 (55%), Gaps = 15/199 (7%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 M VSA +AE++ILE N+ LR +L + KQ F+++ +KFL ++ + L N KYK Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EECKDLI+S+L EE+QF+E +LAE + A LR + L+ +Q EL LR+K +EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120 Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192 + QH+ + LL Q Q F EQ+ +G +L LV KL+ EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180 Query: 193 NDKTKELDKVQESPAPREE 211 D+ K L APR E Sbjct: 181 EDRQKPL-------APRSE 192 >gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 322 Score = 125 bits (313), Expect = 9e-29 Identities = 78/199 (39%), Positives = 111/199 (55%), Gaps = 15/199 (7%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 M VSA +AE++ILE N+ LR +L + KQ F+++ +KFL ++ + L N KYK Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EECKDLI+S+L EE+QF+E +LAE + A LR + L+ +Q EL LR+K +EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120 Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192 + QH+ + LL Q Q F EQ+ +G +L LV KL+ EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180 Query: 193 NDKTKELDKVQESPAPREE 211 D+ K L APR E Sbjct: 181 EDRQKPL-------APRSE 192 >gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 298 Score = 123 bits (309), Expect = 3e-28 Identities = 78/199 (39%), Positives = 110/199 (55%), Gaps = 15/199 (7%) Query: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 M VSA +AE++ILE N+ LR +L + KQ F+++ +KFL ++ + L N KYK Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 EECKDLI+S+L EE+QF+E +LAE + A LR + L+ +Q EL LR+K +EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120 Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192 + QH+ + LL Q Q F EQ+ +G +L LV KL EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180 Query: 193 NDKTKELDKVQESPAPREE 211 D+ K L APR E Sbjct: 181 EDRQKPL-------APRSE 192 >gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo sapiens] Length = 2346 Score = 81.3 bits (199), Expect = 2e-15 Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 22/209 (10%) Query: 81 EECKDLIKSMLREELQFK----EEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREG 136 ++ + LI+ + + E Q EEKLAE+L+ A +Y L+ Q REL LR+K+REG Sbjct: 1436 KDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREG 1495 Query: 137 RDASHSLNQH-------LQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTD 189 R + + +H + LL + D GQ FREQLA+G +L L KLS ++ Sbjct: 1496 RGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS 1555 Query: 190 EDENDKTKELDKVQESPAPREEQKAEEK----EVPEDSLEECAITYSNSHGPSDSNPPHK 245 E + + L A R ++ +EK EV + L+ ++T S+SH SDS+ Sbjct: 1556 EKDQAGLEPL-------ALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPS 1608 Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDA 274 + S+E + S + + SE + E + A Sbjct: 1609 STSFLSDELEACSDMDIVSEYTHYEEKKA 1637 Score = 38.5 bits (88), Expect = 0.012 Identities = 57/279 (20%), Positives = 114/279 (40%), Gaps = 51/279 (18%) Query: 28 WSSEK------AEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYE 81 W +EK E NI +N L +K+Q L+ + L + N K Sbjct: 421 WEAEKYNEIRTQEQNIQHLNHSL-----SHKEQ--------LLQEFRELLQYRDNSDKTL 467 Query: 82 ECKDLIKSMLREELQFK--------EEKLAEQLKQAEELRQYKVLVHSQERELIQLREKL 133 E +++ LR+ + K +EK + ++ +ELRQ ++ V ++ +L E+L Sbjct: 468 EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDL----ERL 523 Query: 134 REGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN 193 R+ ++ + Q +++LL ++G + EQL+ C+ + L E+ Sbjct: 524 RDVLSSNEATMQSMESLL------RAKGLEV-EQLSTTCQNLQWL----------KEEME 566 Query: 194 DKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253 K K QES + + ++ +E+ + T GP S + + + Sbjct: 567 TKFSRWQKEQESIIQQLQTSLHDR---NKEVEDLSATLLCKLGPGQSEIAEELCQRLQRK 623 Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKA 292 +++ L+ D E + + LL++ + E+E A Sbjct: 624 ERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAA 662 Score = 37.0 bits (84), Expect = 0.034 Identities = 85/422 (20%), Positives = 154/422 (36%), Gaps = 103/422 (24%) Query: 42 EKLRPQLAENKQQFRNMKQKFLVTQMAGFL-ANQQNKYK--------------------- 79 + LR QL++ KQ+++++++K L+++ F AN+ KY+ Sbjct: 1214 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 1273 Query: 80 ---YEECKDLIKSMLREELQFKEEKLAEQLKQ--------AEELRQYKVLVHSQERE--- 125 YE C REE E + LK+ +E+ R+ L S ER+ Sbjct: 1274 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 1333 Query: 126 -----------------LIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQL 168 ++ LR+ +++ + + N+ +Q L + + S D+ L Sbjct: 1334 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVR-SLSVTSDYSSSL 1392 Query: 169 AEGCRL-ARHLVHKLSPENDTDEDEN------------------DKTKELDKVQESPAPR 209 +L A + SP + DEDE D + +V + A Sbjct: 1393 ERPWKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQL 1452 Query: 210 EEQKAEEKEVPE----------DSL----------------EECAITYSNSHGPSDSNPP 243 + EEK E DSL E I Y + D+ Sbjct: 1453 PKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKS 1512 Query: 244 HKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWIC 303 +++ +++ D + + + + L L ++ E++ P + L Sbjct: 1513 FEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRL--- 1569 Query: 304 GLKLQESEEK-EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362 +LQE E+ EVLQ + R T S H +S S++ T E + CS D+ SE+ Sbjct: 1570 SRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEY 1629 Query: 363 SN 364 ++ Sbjct: 1630 TH 1631 Score = 29.6 bits (65), Expect = 5.4 Identities = 53/233 (22%), Positives = 87/233 (37%), Gaps = 33/233 (14%) Query: 9 VPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAEN---KQQFRNMKQKFLVT 65 V G SS ++V + S P ++ E ++ EI LR +L E+ + R + L + Sbjct: 1821 VSGDLSSGSSVYQLNSK-PTGADLLEEHLGEIRN-LRQRLEESICINDRLREQLEHRLTS 1878 Query: 66 QMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERE 125 G Y + + I + E +E+ Q + + R+ HSQE E Sbjct: 1879 TARG---RGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSRE-----HSQETE 1930 Query: 126 LIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPE 185 + R+A S HLQ L +H + Q E L E + H Sbjct: 1931 SL---------REALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHF------- 1974 Query: 186 NDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPS 238 +E +E D + +Q+ EEK+ +SL+ Y +G S Sbjct: 1975 ----REERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNS 2023 >gi|7657138 golgi integral membrane protein 4 [Homo sapiens] Length = 696 Score = 57.4 bits (137), Expect = 2e-08 Identities = 70/327 (21%), Positives = 134/327 (40%), Gaps = 44/327 (13%) Query: 52 KQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLA-EQLKQAE 110 ++Q R K++ + A L Y K +IK E Q ++++LA +Q+++A+ Sbjct: 366 EEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425 Query: 111 ELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAE 170 +LR+++ +H Q + LR++ ++ + + + QA L + + +EQL Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQH------QEQL-- 477 Query: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAIT 230 R H + +ND + D+ + +E R+ Q +E E Sbjct: 478 -----RQQAHYDAMDNDIVQGAEDQGIQ---GEEGAYERDNQHQDEAEGDP--------- 520 Query: 231 YSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQ--DEWQDALNILLENQNDDEEE 288 N H P + P + + ++ V I D ++Q DE+++A + EN D+ EE Sbjct: 521 -GNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579 Query: 289 EGKAPVPPQVT-----LWICG-LKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEG 342 + ++ + T L + G QE E Q+ EE V ++ + E Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639 Query: 343 TFLALVEQKVCSAQDVASEHSNSKGEE 369 T+ D ++ N+ GEE Sbjct: 640 TY---------GENDENTDDKNNDGEE 657 Score = 38.5 bits (88), Expect = 0.012 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 18/130 (13%) Query: 104 EQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQD 163 ++ ++AE++R+ + ++E++ +++ E + +HL PD+ +++ + Sbjct: 560 DEFEEAEQVREENLPDENEEQKQSNQKQENTE-------VEEHLVMAGNPDQQEDNVDEQ 612 Query: 164 FREQLAEGC---------RLARHLVHKLSPEND--TDEDENDKTKELDKVQESPAPREEQ 212 ++E+ E R H + END TD+ ND ++ + P REE Sbjct: 613 YQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEH 672 Query: 213 KAEEKEVPED 222 EE+E ED Sbjct: 673 YEEEEEEEED 682 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 54.7 bits (130), Expect = 2e-07 Identities = 53/276 (19%), Positives = 119/276 (43%), Gaps = 31/276 (11%) Query: 42 EKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEE- 100 EK+R Q +Q+ + +Q+ + + + Q+ K +E K + +REE + +E+ Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523 Query: 101 ---KLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHD 157 + E++++ EE+ + K +H QE ++ + EK+ + H + ++ ++ + Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR-----EQEE 578 Query: 158 NSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEK 217 Q+ E++ E R K+ + + +++ +K E QE +E+K +E+ Sbjct: 579 KVWRQE--EKIREQEEKIREQEEKIREQEEMTQEQEEKMGE----QEEKMCEQEEKMQEQ 632 Query: 218 EVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNI 277 E EE + KI +E+K+ + E + W+ + Sbjct: 633 EEKMRRQEE--------------KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 678 Query: 278 LLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 + + E+EE + +W ++L++ EEK Sbjct: 679 CEQEEKMQEQEEKMR--RQEEKMWEQEVRLRQQEEK 712 Score = 50.8 bits (120), Expect = 2e-06 Identities = 75/382 (19%), Positives = 154/382 (40%), Gaps = 59/382 (15%) Query: 30 SEKAE--MNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLI 87 SEK+E +N+ E+ KL QQ + L ++ A Q + + E + + Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355 Query: 88 KSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHL 147 E++ +EEK+ E E++++ + + QE ++ + EK+R + + + Sbjct: 356 NQQQEEKMWRQEEKIQEW---EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412 Query: 148 --QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSP-----ENDTDEDENDKTKELD 200 Q + +K + + Q+ E + E R L K+ E + E +K +E + Sbjct: 413 RRQEEMMWEKEEKMRRQE--EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470 Query: 201 KVQESPAP--REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNS 258 K QE A R+E+K E+E EE K+ +E+K++ Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEE---------------------KMWRQEEKIHE 509 Query: 259 ILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQD 318 + E + E ++ + + + E+EE +W K+ E EEK ++ Sbjct: 510 QEKIREEEKRQEQEE---MWRQEEKIREQEE----------IWRQKEKIHEQEEK--IRK 554 Query: 319 SPEERVTTSCSDHDVSQSYQPCEGTF------LALVEQKVCSAQD-VASEHSNSKGEETP 371 E+ HD + + E + E+K+ ++ + + ++ +E Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614 Query: 372 LGFPDTKYCWKDEKDERMSQKV 393 +G + K C ++EK + +K+ Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKM 636 Score = 35.8 bits (81), Expect = 0.075 Identities = 74/334 (22%), Positives = 128/334 (38%), Gaps = 49/334 (14%) Query: 14 SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73 ++ TN S G S E + + E LR +L R + + QMA + + Sbjct: 152 NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ 211 Query: 74 QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122 K E +DLI S L + +F E +A Q K+A EEL + + + + Sbjct: 212 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 270 Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173 + EL + KL+E S +Q + K + + ++QL AE Sbjct: 271 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 330 Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSN 233 L + L +S + +EN+ L++ QE R+E+K +E E EE Sbjct: 331 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE------- 382 Query: 234 SHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAP 293 KI +E+K+ + W+ + + + E+EE Sbjct: 383 --------------KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR- 427 Query: 294 VPPQVTLWICGLKLQESEEK----EVLQDSPEER 323 + +W K++E EEK E +++ E+R Sbjct: 428 -RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460 Score = 33.5 bits (75), Expect = 0.37 Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 18/135 (13%) Query: 34 EMNILEINEKLRPQLAENKQQFRNM--------KQKFLVTQMAGFLANQQNKYKYEECK- 84 E I E EK+R Q ++Q M +Q+ + + + Q+ K + +E K Sbjct: 591 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI 650 Query: 85 ----DLIKSMLREELQFKEEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLREG 136 + I+ E +Q +EEK+ EQ +Q E++++ + + QE ++ + +LR+ Sbjct: 651 REQEEKIREQ-EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709 Query: 137 RDASHSLNQHLQALL 151 + +HL+A + Sbjct: 710 EEKMQEHQEHLEAAI 724 >gi|115511012 coiled-coil domain containing 136 [Homo sapiens] Length = 1154 Score = 51.2 bits (121), Expect = 2e-06 Identities = 71/336 (21%), Positives = 137/336 (40%), Gaps = 46/336 (13%) Query: 13 TSSATNVTMVVSAGPWSS-EKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFL 71 T+S +++T S G SS + + + + P E+ ++F M K L+ A Sbjct: 806 TTSNSSITYKKSYGSTSSSDTCQKSFVSSCTDEEPAEPEDMERFEEMVVKVLIKLQAVQA 865 Query: 72 ANQQNKYKYEECKDLIKSMLREELQFKEEKLA--EQLKQAEELRQYKVLVHSQERELIQL 129 Q ++ ++ + ++ ++ +L ++ KEE A + K+ E + + + + E+ +L Sbjct: 866 MYQISQEEHSQLQEQMEKLLAKQKDLKEELDACEREFKECMECLEKPMAPQNDKNEIKEL 925 Query: 130 REKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHK-------- 181 + KLRE + + LL + Q Q +E+L + R R V K Sbjct: 926 QTKLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQEELRQ-LREKRPSVVKEARGKNAN 984 Query: 182 ---------------LSPENDTDEDENDKTK-------------ELDKVQESPAPREEQK 213 P +DT E + + K +LD + + +EE + Sbjct: 985 KNMNKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAKEEEKKEEME 1044 Query: 214 AEEKEVPEDSLEECA-ITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQ 272 E+K+V E++ E+C + P ++ + +EEDK DSE +D+ Sbjct: 1045 EEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQEE--NEEDKEEEEKEEDSEEEEDDAD 1102 Query: 273 DALNILLEN---QNDDEEEEGKAPVPPQVTLWICGL 305 +L EN + + ++ P PP +L + GL Sbjct: 1103 SSLESPEENNPLRLSESKKSSPTPNPPIFSLPLVGL 1138 Score = 37.7 bits (86), Expect = 0.020 Identities = 58/305 (19%), Positives = 127/305 (41%), Gaps = 17/305 (5%) Query: 39 EINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFK 98 E NE L+ QL + + + R +K + + NQ K C+ + + + + Sbjct: 384 EQNELLKMQL-QLQTELRQLK-----VMKSTLVENQSEKELL--CRLQKLHLQHQNVTCE 435 Query: 99 EEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDN 158 +EKL E+ +Q +E Q R+ + ++ E +H+ Q ++ L K + Sbjct: 436 KEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDEL 495 Query: 159 SQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDK-VQESPAPREEQKAEEK 217 + + +QL + L + + +L + ED+ + D + +E+ KA +K Sbjct: 496 ERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQK 555 Query: 218 EVPEDSLEECAITYSNSHGPSDSNPPHKNI-KITSEEDKVNSILVVDSESSQDEWQDALN 276 E+ + +E+C + + + + ++T K S L++ S+ + +D Sbjct: 556 EMGQLQMEQCELLEDQRRMQEEQGQLQEELHRLTLPLPK--SGLLLKSQELLTKLEDLCE 613 Query: 277 ILLENQNDDEEEE-----GKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDH 331 + L Q EE++ + Q+ + + +ES +EVL++ + ++ S + Sbjct: 614 LQLLYQGMQEEQKKLIQNQDCVLKEQLEIHEELRRFKESHFQEVLENPDDSKLAKSSKCN 673 Query: 332 DVSQS 336 QS Sbjct: 674 RNKQS 678 Score = 32.3 bits (72), Expect = 0.83 Identities = 61/281 (21%), Positives = 108/281 (38%), Gaps = 20/281 (7%) Query: 129 LREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF---REQLAEGCRLARHLVHKLSPE 185 L+E+L+E R+ H LN+ +AL + Q D R Q A L + S E Sbjct: 222 LQEELQELRERYHFLNEEYRALQESNSSLTGQLADLESERTQRATERWLQSQTLSMTSAE 281 Query: 186 NDTDE-DENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPH 244 + T E D + E+ +++ EEQ K + E C H S Sbjct: 282 SQTSEMDFLEPDPEMQLLRQQLRDAEEQMHGMKNKCQ---ELCCELEELQHHRQVSEEEQ 338 Query: 245 KNIK--ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKA-PVPPQVTLW 301 + ++ + +++V S + +E + L L + + ++E+ + + Q+ Sbjct: 339 RRLQRELKCAQNEVLRFQTSHSVTQNEELKSRLCTLQKKYDTSQDEQNELLKMQLQLQTE 398 Query: 302 ICGLKLQES------EEKEVL---QDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKV 352 + LK+ +S EKE+L Q + +C + + Q + + Sbjct: 399 LRQLKVMKSTLVENQSEKELLCRLQKLHLQHQNVTCEKEKLLERQQQLQEELQCHEAELQ 458 Query: 353 CSAQDVAS-EHSNSKGEETPLGFPDTKYCWKDEKDERMSQK 392 VAS + SN K ET + K ++ KDE QK Sbjct: 459 HLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQK 499 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 50.8 bits (120), Expect = 2e-06 Identities = 74/384 (19%), Positives = 157/384 (40%), Gaps = 63/384 (16%) Query: 28 WSSE----KAEMNILEINEKLRPQ---LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 W E + E + E EK+R Q + E +++ R +++K ++Q K + Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM----------HEQEKIRE 408 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 +E K + +RE+ + ++E+ A+ +Q E++R+ + + QE+++ + EK+ E Sbjct: 409 QEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467 Query: 141 HSLNQHLQALLTPDK---HDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTK 197 + Q + + H+ + +E++ E R K+ + + ++ +K + Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527 Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257 E QE R+E+K E+ E+ E + + + K+ +E+K+ Sbjct: 528 E----QEEKMWRQEEKIREQ---EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580 Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK-EVL 316 E + W+ I + + E+EE +W K++E EEK + Sbjct: 581 -------EQEEKVWRQEEKIREQEEKRQEQEE---------KMWKQEEKIREQEEKIQEQ 624 Query: 317 QDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPD 376 ++ E+ +++Q + G E+K+C ++ E EET Sbjct: 625 EEKIREQEEKIREQEEMTQEQEEKMGE----QEEKMCEQEEKMQEQ-----EET------ 669 Query: 377 TKYCWKDEKDERMSQKVAFLLDEK 400 W+ E+ R +K +EK Sbjct: 670 ---MWRQEEKIREQEKKIREQEEK 690 Score = 48.9 bits (115), Expect = 9e-06 Identities = 58/285 (20%), Positives = 119/285 (41%), Gaps = 21/285 (7%) Query: 32 KAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECK---DLIK 88 + E I E E R + ++Q+ + KQ+ V + + Q+ K + +E K K Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539 Query: 89 SMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQ 148 +EE+ +EEK+ EQ K EE ++ + QE ++ + EK+RE + + + Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQE-----QEDKMWRQEEKIREQEEKVWRQEEKI- 593 Query: 149 ALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAP 208 + + Q+ E++ + R K+ + + ++ +K +E QE Sbjct: 594 ------REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE----QEEMTQ 643 Query: 209 REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQ 268 +E+K E+E EE + + + KI +E+K+ + E + Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703 Query: 269 DEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313 W+ + + + E+EE + +W ++L++ EEK Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMR--RQEEKMWEQEVRLRQQEEK 746 Score = 35.8 bits (81), Expect = 0.075 Identities = 58/314 (18%), Positives = 125/314 (39%), Gaps = 17/314 (5%) Query: 93 EELQFKEEKLAEQLKQAE-ELRQYKVLVHSQERELIQLREKLREGR---DASH------S 142 EEL+ K KL E+L+ E E + ++ V +R+L + + L + + +A H S Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276 Query: 143 LNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKV 202 ++ LQA + ++ N Q E++ + K+ + + ++ +K +E Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE---- 332 Query: 203 QESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKV--NSIL 260 QE R+E+ EKE EE + K K+ +E+ + Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392 Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320 + + E E + + Q +++ E + + +W K++E EEK Q+ Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452 Query: 321 EERVTTSCSDHD-VSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDTKY 379 R + + + + + E + E+K+ +++ + +E + + K Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512 Query: 380 CWKDEKDERMSQKV 393 ++EK +K+ Sbjct: 513 WRQEEKIREQEEKI 526 Score = 35.0 bits (79), Expect = 0.13 Identities = 57/233 (24%), Positives = 94/233 (40%), Gaps = 22/233 (9%) Query: 14 SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73 ++ TN S G S E + + E LR +L R + + QMA + + Sbjct: 91 NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ 150 Query: 74 QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122 K E +DLI S L + +F E +A Q K+A EEL + + + + Sbjct: 151 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 209 Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173 + EL + KL+E S +Q + K + + ++QL AE Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269 Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEE 226 L + L +S + +EN+ L++ QE R+E+K +E E EE Sbjct: 270 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 321 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 50.1 bits (118), Expect = 4e-06 Identities = 65/303 (21%), Positives = 134/303 (44%), Gaps = 47/303 (15%) Query: 29 SSEKAEMNILEINEKLRPQLAENKQQFRNMKQ--------KFLVTQMAGFLANQQNKYKY 80 ++E+ + E+ EKLR +E + N+K+ KFL+ Q+ ++ + Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240 Query: 81 EECKDLIKSMLREELQF--KEEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLR 134 EE ++ K + ++E + +EE+L EQ +Q E++R+ + + QE+EL + ++LR Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300 Query: 135 EGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEND 194 E + L + + + ++ Q + REQ + R L + + ++ D Sbjct: 301 EQK----KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356 Query: 195 KTKELDKVQESPAPREEQKAEEKEV--PEDSLEECAITYSNSHGPSDSNPPHKNIKITSE 252 + + + + E +EE+ E++++ E+ ++E +I Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQE-------------------EERIRER 397 Query: 253 EDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQ--VTLWICGLKLQES 310 E K+ + E + E ++ + EN + EE+E + P+ LW K+QE Sbjct: 398 EKKMR-----EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQ 451 Query: 311 EEK 313 EEK Sbjct: 452 EEK 454 Score = 36.2 bits (82), Expect = 0.057 Identities = 59/332 (17%), Positives = 136/332 (40%), Gaps = 53/332 (15%) Query: 31 EKAEMNILEINEKLRPQ----------LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 ++ E + E EK+R Q L E ++Q R +QK + + +++ + K Sbjct: 313 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 372 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLK----QAEELRQYKVLVHSQERELIQLREK---- 132 E ++ K +EE +EE++ E+ K + E +R+ + + QE + + EK Sbjct: 373 ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432 Query: 133 --LREGRD---ASHSLNQHLQALLTPDKHDNSQ----GQDFR-----------EQLAEGC 172 L E ++ + + + + ++ Q GQ+ + +Q+ E Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492 Query: 173 RLARHLVHKLSPENDTDEDENDKTKELD---KVQESPAPREEQKAEEKEVPEDSLEECAI 229 R K+ + + +++++ +E + + Q+ +EE+ EEK+ E + Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK---- 548 Query: 230 TYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEE 289 T+ + + K EE+++ + +++ ++ + E + +E+E Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608 Query: 290 GKAPVPPQVTLWICGLKLQESEEKEVLQDSPE 321 K +W K+ E EE++ +Q+ E Sbjct: 609 EK--------MWEQEEKMWEQEEEDKMQEQEE 632 Score = 35.8 bits (81), Expect = 0.075 Identities = 37/210 (17%), Positives = 93/210 (44%), Gaps = 20/210 (9%) Query: 30 SEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKS 89 +++ E + EK+R + +++ + +++ ++ + + Q+ K + +E K + Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601 Query: 90 MLREELQFKEEKLAEQ-------------LKQAEELRQYKVLVHSQERELIQLREKLREG 136 E++Q +EEK+ EQ +Q E + + + + QE ++ + EK+RE Sbjct: 602 ---EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658 Query: 137 RDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKT 196 + + +Q + + Q E++ E R K+ + + + +K Sbjct: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718 Query: 197 KELDKVQESPAPREEQKAEEKEVPEDSLEE 226 ++++E +EE+ ++KE ++ L E Sbjct: 719 WGQEEMRE----KEERIRDQKEKMQERLPE 744 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 49.7 bits (117), Expect = 5e-06 Identities = 71/309 (22%), Positives = 136/309 (44%), Gaps = 60/309 (19%) Query: 30 SEKAE--MNILEINEKLR------PQLAENKQQFRNMKQKFLVTQMAGFLANQQNK-YKY 80 SEK+E +N+ E+ KL PQ+ N Q +Q+ + + + Q+ K ++ Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298 Query: 81 EE--------CKDLIKSMLREE--LQFKEEKLAEQ---LKQAEELRQYKVLVHSQERELI 127 EE ++ + M R+E L+ +E++L EQ L++ +ELR+ + + QE ++ Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358 Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187 + EK+RE + + + + L +K Q Q R+Q ++ +++ Sbjct: 359 EQEEKMREQEE---KMWRQEERLWEQEKQMREQEQKMRDQ-----------EERMWEQDE 404 Query: 188 TDEDENDKTKELDKVQES-PAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKN 246 ++ ++ +E +K+ E REE+K +E+E EE + Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE---------------KMQEE 449 Query: 247 IKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQ--VTLWICG 304 +I E K+ + E + E ++ + EN + EE+E + P+ LW Sbjct: 450 ERIREREKKMR-----EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-Q 503 Query: 305 LKLQESEEK 313 K+QE EEK Sbjct: 504 EKMQEQEEK 512 Score = 38.5 bits (88), Expect = 0.012 Identities = 56/303 (18%), Positives = 128/303 (42%), Gaps = 34/303 (11%) Query: 31 EKAEMNILEINEKLRPQ----------LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 ++ E + E EK+R Q L E ++Q R +QK + + +++ + K Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLRE-KLREGRDA 139 E ++ K + E +E+K+ EQ K+ + + QE E I+ RE K+RE + Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE-----KMQEEERIREREKKMREEEET 465 Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLV---HKLSPENDTDEDENDKT 196 + +Q + +N Q+ +E + + + K+ + + ++ +K Sbjct: 466 MREQEEKMQ-----KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520 Query: 197 KELDKV--QESPAPREEQKAEEKE---VPEDSLEECAITYSNSHGPSDSNPPHKNIKITS 251 ++ +++ QE R+E+ E+++ E+ + + + + + K Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580 Query: 252 EEDKV-NSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQES 310 +E+K+ + + E E ++ ++ Q + +E+ + + +W K+QE Sbjct: 581 QEEKMREEERMREREKKMREEEE----MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636 Query: 311 EEK 313 EEK Sbjct: 637 EEK 639 Score = 34.7 bits (78), Expect = 0.17 Identities = 50/256 (19%), Positives = 97/256 (37%), Gaps = 32/256 (12%) Query: 28 WSSEKA---EMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECK 84 W EK E + E EK+R Q + Q M++K + + +Q+ K + EE Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW--DQEEKMREEERM 591 Query: 85 DLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLN 144 + +REE + E+ + +Q E++++ + + QE ++ + EK+ E + Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651 Query: 145 QHL--QALLTPDK-----HDNSQGQDFREQLAEGCRLARHLVHKLSP------------- 184 + + Q L K H+ Q Q+ ++ E + K Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711 Query: 185 -------ENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGP 237 E E+E ++ +K+QE +EQ+ E E E E+ + P Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771 Query: 238 SDSNPPHKNIKITSEE 253 ++ K+ +E Sbjct: 772 EQKEKLWEHEKMQEQE 787 Score = 33.5 bits (75), Expect = 0.37 Identities = 43/206 (20%), Positives = 92/206 (44%), Gaps = 24/206 (11%) Query: 34 EMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLRE 93 E I E +K+R E ++ R ++K + Q ++ +++ + + + + + Sbjct: 449 EERIREREKKMR----EEEETMREQEEK-MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503 Query: 94 E-LQFKEEKLAEQ---LKQAEEL--------RQYKVLVHSQERELIQLREKLREGRDASH 141 E +Q +EEK+ EQ ++ EE+ RQ K+ QE ++ + EK+R+ Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM--REQEDQMWEQEEKMRDQEQKMW 561 Query: 142 SLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD- 200 + ++ + + D E++ E R+ R K+ E + ++ +K +E + Sbjct: 562 DQEERMEK---KTQEQEKKTWDQEEKMREEERM-REREKKMREEEEMMREQEEKMQEQEE 617 Query: 201 KVQESPAPREEQKAEEKEVPEDSLEE 226 K+QE EQ+ + +E E E+ Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQ 643 Score = 30.0 bits (66), Expect = 4.1 Identities = 40/198 (20%), Positives = 89/198 (44%), Gaps = 25/198 (12%) Query: 31 EKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSM 90 ++ E + E EK+ Q + +Q R +QK + + +Q K + +E K + Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM--QEQEKMQEQEEKIWEQEK 691 Query: 91 LREELQFKEEKL--AEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQ 148 + ++ Q +E+K E++++ E +R+ + + +E + + EK++E + + + Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751 Query: 149 ALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAP 208 ++ + Q+ E++ E RL PE E++K +E +K+ E Sbjct: 752 -----EQEEKMWEQE--EKMWEQQRL---------PEQKEKLWEHEKMQEQEKIWE---- 791 Query: 209 REEQKAEEKEVPEDSLEE 226 +E+K ++E EE Sbjct: 792 -QEEKMRDQEEKMRGQEE 808 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 48.5 bits (114), Expect = 1e-05 Identities = 63/315 (20%), Positives = 131/315 (41%), Gaps = 40/315 (12%) Query: 28 WSSE----KAEMNILEINEKLR---PQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80 W E + E + E EK+R + E +++ R +++K ++Q K + Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM----------HEQEKIRE 394 Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLRE-GRDA 139 +E K + +RE+ + ++E+ A+ +Q E++R+ + + QE+++ + EK+ E + Sbjct: 395 QEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453 Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFR--EQLAEGCRLARHLVHKLSPENDTDEDENDKTK 197 Q + + ++ Q + +R E++ E ++ R K+ + + D+ +K + Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI-RKQEEKVWRQEEKMHDQEEKIR 512 Query: 198 ELDKV---QESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPP------HKNIK 248 E ++ QE +E+K E+E EE G + + K Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572 Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308 I +E+K+ E + W+ I + + E+EE +W K+ Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE---------KMWEQEEKMC 623 Query: 309 ESEEKEVLQDSPEER 323 E EEK Q+ R Sbjct: 624 EQEEKMQEQEEKMRR 638 Score = 40.0 bits (92), Expect = 0.004 Identities = 41/190 (21%), Positives = 89/190 (46%), Gaps = 14/190 (7%) Query: 42 EKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREE--LQFKE 99 E++ Q + +Q + KQ+ V + + +Q+ K + +E K M R+E ++ +E Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK-----MWRQEEKIREQE 529 Query: 100 EKLAEQ---LKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKH 156 EK+ EQ +++ EE+ Q + ++ E +Q +EK+R + + ++ + Sbjct: 530 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589 Query: 157 DNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEE 216 + + E++ E + + K+ + + ++ +K +E QE R+E+K E Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMWE 645 Query: 217 KEVPEDSLEE 226 +EV EE Sbjct: 646 QEVRLRQQEE 655 Score = 38.5 bits (88), Expect = 0.012 Identities = 39/193 (20%), Positives = 86/193 (44%), Gaps = 29/193 (15%) Query: 32 KAEMNILEINEKLRPQLAENKQQFRNM-KQKFLVTQMAGFLANQQNKYKYEECKDLIKSM 90 K E + EK+ Q + ++Q M +Q+ + + + Q+ K + +E Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE-------- 543 Query: 91 LREELQFKEEKLAEQ---LKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHL 147 E +Q +EEK+ EQ +++ E++R+ + + QE ++ + +EK+RE + + + Sbjct: 544 --EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE---KIWEQE 598 Query: 148 QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKV--QES 205 + + ++ Q + EQ + C E E E ++ +K+ QE Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMC----------EQEEKMQEQEEKMRRQEEKMWEQEV 648 Query: 206 PAPREEQKAEEKE 218 ++E+K +E + Sbjct: 649 RLRQQEEKMQEHQ 661 Score = 36.6 bits (83), Expect = 0.044 Identities = 74/334 (22%), Positives = 129/334 (38%), Gaps = 49/334 (14%) Query: 14 SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73 ++ TN S G S E + + E LR +L R + + QMA + + Sbjct: 91 NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ 150 Query: 74 QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122 K E +DLI S L + +F E +A Q K+A EEL + + + + Sbjct: 151 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 209 Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173 + EL + KL+E S +Q + K + + ++QL AE Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269 Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSN 233 L + L +S + +EN+ L++ QE R+E+K +E E EE Sbjct: 270 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE------- 321 Query: 234 SHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAP 293 KI +E+K+ + W+ + + + E+EE Sbjct: 322 --------------KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367 Query: 294 VPPQVTLWICGLKLQESEEK----EVLQDSPEER 323 + + +W K++E EEK E +++ E+R Sbjct: 368 L--EEMMWEKEEKIRELEEKMHEQEKIREQEEKR 399 Score = 35.4 bits (80), Expect = 0.098 Identities = 27/121 (22%), Positives = 60/121 (49%), Gaps = 19/121 (15%) Query: 38 LEINEKLRPQ---LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREE 94 ++ EK+R Q + E +++ R K+K + + + Q+ K + +E E Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEK--IREQEEKIWEQEEKIREQE----------EM 607 Query: 95 LQFKEEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQAL 150 +Q +EEK+ EQ +Q E++++ + + QE ++ + +LR+ + +HL+A Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667 Query: 151 L 151 + Sbjct: 668 I 668 >gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] Length = 1780 Score = 48.1 bits (113), Expect = 1e-05 Identities = 61/258 (23%), Positives = 118/258 (45%), Gaps = 34/258 (13%) Query: 81 EECKDLIKSMLREELQFKEEKLAEQLKQA----EELRQYKVLVHSQERELIQLREKLREG 136 E +D +K+ ++L KE KL E++ Q ++++ L +E Q EKL+E Sbjct: 1166 EHLQDSVKNT--KDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEE 1223 Query: 137 RDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKT 196 AS + Q+L+A L + D + D +E+L + + + + ++S D D+ K Sbjct: 1224 LSASSARTQNLKADLQRKEEDYA---DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI 1280 Query: 197 KELDKVQESPAPREEQKAE-----EKEVPEDSLEECAITYSNSHGPSDSNPPHK---NIK 248 EL+K + + + K ++++ +EE Y + D N K +++ Sbjct: 1281 NELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERA--CKDLNVKEKIIEDMR 1338 Query: 249 ITSEED---KVNSILVVDSESSQ--------DEWQDALNIL--LENQNDDEEEEGKAPVP 295 +T EE +V V++++ + ++W++ N L NQ ++E E V Sbjct: 1339 MTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1398 Query: 296 PQVTLWICGLKLQESEEK 313 ++T +LQESE+K Sbjct: 1399 GKLT--NLQDELQESEQK 1414 Score = 33.9 bits (76), Expect = 0.28 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 15/148 (10%) Query: 4 RFFSPVPGST-----SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNM 58 + F PV S S++ + + V S E + +++E +E L +L EN ++ +N+ Sbjct: 491 KLFGPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLME-DEDLVEEL-ENAEETQNV 548 Query: 59 KQKFLVTQMAGFLANQQNKYKYEECK---DLIKSMLREELQFKEEKLAEQLKQAEELRQY 115 + K L + L + +EE + DLI+ + ++ + K+EKL + K EE+ Q Sbjct: 549 ETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQE 608 Query: 116 KVLVHSQ-----ERELIQLREKLREGRD 138 +Q + L+Q RE L E + Sbjct: 609 FTQYWAQREADFKETLLQEREILEENAE 636 Score = 33.1 bits (74), Expect = 0.49 Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 41/221 (18%) Query: 80 YEECKDLIKSMLR-----EELQFKEEKLAEQLK-QAEELRQYKVLVHSQERELIQLREKL 133 +EECK+++K+ + EEL+ + EKL ++K +E + K H + +L++ +E L Sbjct: 1021 WEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETL 1080 Query: 134 -----REGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDT 188 E ++ + +L+ +Q ++ +G+ +L +G + + +L Sbjct: 1081 IQQLKEELQEKNVTLDVQIQHVV--------EGKRALSELTQGVTCYKAKIKEL------ 1126 Query: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248 + E KV+ S + + EQ EKE LE + S N N+K Sbjct: 1127 -----ETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1181 Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEE 289 ++++ + + QD ++L Q +EEEE Sbjct: 1182 ELKLKEEITQL--------TNNLQDMKHLL---QLKEEEEE 1211 Score = 33.1 bits (74), Expect = 0.49 Identities = 50/241 (20%), Positives = 101/241 (41%), Gaps = 54/241 (22%) Query: 38 LEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSM--LREEL 95 LE E+L +L + K++ +++ K NQ++ ++E D++ + L++EL Sbjct: 1359 LEEVERLATELEKWKEKCNDLETK----------NNQRSNKEHENNTDVLGKLTNLQDEL 1408 Query: 96 QFKEEK--------------LAEQLKQAEELRQYKVLVHSQERE------------LIQL 129 Q E+K L Q K+AE +R ++ ++++RE QL Sbjct: 1409 QESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQL 1468 Query: 130 RE------KLREGRD-ASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKL 182 E K RE RD +L L+AL++ + +++ + + ++E ++ ++ + Sbjct: 1469 TEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQIM-DI 1527 Query: 183 SPENDTDEDENDKTKELDKVQESPAPREEQKAEEK-EVPEDSLEECAITYSNSHGPSDSN 241 P+ + D DK+Q P + + K E L+ C ++ N Sbjct: 1528 KPKRISSADP-------DKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTRFPK 1580 Query: 242 P 242 P Sbjct: 1581 P 1581 Score = 30.0 bits (66), Expect = 4.1 Identities = 54/271 (19%), Positives = 111/271 (40%), Gaps = 18/271 (6%) Query: 76 NKYKYEECK---DLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQE-RELIQLRE 131 N+ K E K +LIK+ +EEL+ +E + ++ L Q E K++ +Q +ELI + + Sbjct: 678 NQIKAELAKTKGELIKT--KEELKKRENE-SDSLIQELETSNKKIITQNQRIKELINIID 734 Query: 132 KLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLA--EGCRLARHLVHKLSPE---- 185 + + + +L H++ + ++ +L E + + K+ E Sbjct: 735 QKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRV 794 Query: 186 NDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPE-DSLEECAITYSNSHGPSDSNPPH 244 N+ + +++ + + S A E+QK E+ P +E+ + N+ G Sbjct: 795 NENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTI 854 Query: 245 KNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICG 304 +N +E+K + + + N+ L + + + L + Sbjct: 855 ENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAI---AELHVQK 911 Query: 305 LKLQESEEKEVLQDSPEERVTTSCSDHDVSQ 335 K QE EEK +++ S E T ++VSQ Sbjct: 912 SKNQEQEEK-IMKLSNEIETATRSITNNVSQ 941 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 47.8 bits (112), Expect = 2e-05 Identities = 50/262 (19%), Positives = 117/262 (44%), Gaps = 41/262 (15%) Query: 32 KAEMNILEINEKLRPQ---LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIK 88 + E + E EK+R Q + E +++ R +++K ++Q K + +E K + Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM----------HEQEKIREQEEKRQEE 369 Query: 89 SMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQ 148 +RE+ + ++E+ A+ +Q E++R+ + + QE + + EK+ E + + +Q Sbjct: 370 EKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428 Query: 149 ALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD-KVQESPA 207 ++ + + Q+ E++ E + R K+ + + +++ +K E + K+ E A Sbjct: 429 -----EQEEKMRRQE--EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481 Query: 208 PREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESS 267 +EQ+ E+ E+ + E + KI +E+K+ + E Sbjct: 482 KMQEQE-EKMRRQEEKIRE------------------QEKKIREQEEKIREQEEMMQEQE 522 Query: 268 QDEWQDALNILLENQNDDEEEE 289 + W+ + + + E+EE Sbjct: 523 EKMWEQEEKMCEQEEKMQEQEE 544 Score = 44.7 bits (104), Expect = 2e-04 Identities = 83/414 (20%), Positives = 162/414 (39%), Gaps = 36/414 (8%) Query: 14 SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73 ++ TN S G S E + + E LR +L Q R + + QMA + + Sbjct: 79 NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQ 138 Query: 74 QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122 K E +DLI S L + +F E +A Q K+A EEL + + + + Sbjct: 139 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 197 Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173 + EL + KL+E S +Q + K + + ++QL AE Sbjct: 198 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 257 Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSN 233 L + L +S + +EN+ L++ QE R+E+K +E+E EE Sbjct: 258 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316 Query: 234 SHGPSDSNPPHKNIKITSEEDKV--NSILVVDSESSQDEWQDALNILLENQNDDEEEEGK 291 + K K+ +E+ + + + E E + + Q +++ E + Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376 Query: 292 APVPPQVTLWICGLKLQESEEK-----EVLQD------SPEERVTTSCSDHDVSQSYQPC 340 + +W K++E EEK E++Q+ EE++ + + Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436 Query: 341 EGTFLALVEQKVCSAQD-VASEHSNSKGEETPLGFPDTKYCWKDEKDERMSQKV 393 + + E+K+ ++ + + + +E +G + K C ++ K + +K+ Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490 Score = 41.6 bits (96), Expect = 0.001 Identities = 46/225 (20%), Positives = 98/225 (43%), Gaps = 34/225 (15%) Query: 34 EMNILEINEKLRPQ-----LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIK 88 E I E+ EK+ Q E +Q+ ++++ + + Q+ K + +E K + Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402 Query: 89 SMLREELQFK----EEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140 + +E + K EEK+ EQ +Q E++R+ + + QE+++ + EK+RE + Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462 Query: 141 HSLNQHL---------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDED 191 + + Q ++ + + Q+ E++ E + R K+ + + ++ Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE--EKIREQEKKIREQEEKIREQEEMMQE 520 Query: 192 ENDKTKELD----------KVQESPAPREEQKAEEKEVPEDSLEE 226 + +K E + + QE R+E+K E+EV EE Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEE 565 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.125 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,737,155 Number of Sequences: 37866 Number of extensions: 899468 Number of successful extensions: 8357 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 132 Number of HSP's successfully gapped in prelim test: 760 Number of HSP's that attempted gapping in prelim test: 5375 Number of HSP's gapped (non-prelim): 2503 length of query: 421 length of database: 18,247,518 effective HSP length: 105 effective length of query: 316 effective length of database: 14,271,588 effective search space: 4509821808 effective search space used: 4509821808 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.