Guide to the Human Genome
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Search of human proteins with 114158664

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
         (421 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            848   0.0  
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...   487   e-138
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...   474   e-134
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]              472   e-133
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]             471   e-133
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]         468   e-132
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]            467   e-132
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...   467   e-132
gi|29789405 hypothetical protein LOC284565 [Homo sapiens]             451   e-127
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]            451   e-127
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...   449   e-126
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   424   e-119
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   424   e-118
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   416   e-116
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   416   e-116
gi|7657017 hypothetical protein LOC25832 [Homo sapiens]               335   5e-92
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...   127   1e-29
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...   125   9e-29
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...   125   9e-29
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...   123   3e-28
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    81   2e-15
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            57   2e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    55   2e-07
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          51   2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    51   2e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    50   4e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    50   5e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    49   1e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    48   1e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    48   2e-05

>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  848 bits (2191), Expect = 0.0
 Identities = 421/421 (100%), Positives = 421/421 (100%)

Query: 1   MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ 60
           MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ
Sbjct: 1   MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ 60

Query: 61  KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH 120
           KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH
Sbjct: 61  KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH 120

Query: 121 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH 180
           SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH
Sbjct: 121 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH 180

Query: 181 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS 240
           KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS
Sbjct: 181 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS 240

Query: 241 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300
           NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL
Sbjct: 241 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300

Query: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360
           WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS
Sbjct: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360

Query: 361 EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQGSFTE 420
           EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQGSFTE
Sbjct: 361 EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQGSFTE 420

Query: 421 D 421
           D
Sbjct: 421 D 421


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score =  487 bits (1253), Expect = e-138
 Identities = 255/358 (71%), Positives = 290/358 (81%), Gaps = 10/358 (2%)

Query: 1   MCLRFFSPVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQ 60
           MCL FFSPVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFRN+K+
Sbjct: 1   MCLPFFSPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKE 60

Query: 61  KFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVH 120
           +  VTQ+AGFLANQQ KYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVH
Sbjct: 61  RCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVH 120

Query: 121 SQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVH 180
           +QEREL QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV 
Sbjct: 121 AQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQ 180

Query: 181 KLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDS 240
           KLSPEND D+DE+ + +  +KVQ+S APRE QKAEEKEVPEDS EECAITYSNSHGP DS
Sbjct: 181 KLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDS 240

Query: 241 NPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300
           N PH+  KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+   
Sbjct: 241 NQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--- 295

Query: 301 WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
                 LQESEE+EV Q+S +E  +T     ++  SYQ    TF +L EQ+VC A D+
Sbjct: 296 -----NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 348



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 397 ELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 456

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 457 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 500

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 501 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 555

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 556 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 584



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 641 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 700

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 701 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 744

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 745 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 799

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 800 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 828



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1636 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1695

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1696 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1739

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1740 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1794

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1795 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1823



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1880 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1939

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1940 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1983

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1984 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2038

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2039 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2067



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2124 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2183

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2184 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2227

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2228 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2282

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2283 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2311



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2368 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2427

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2428 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2471

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2472 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2526

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2527 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2555



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2781 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2840

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2841 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2884

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2885 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2939

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2940 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2968



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 3532 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3591

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 3592 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3635

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 3636 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3690

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 3691 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3719



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 54/184 (29%), Positives = 83/184 (45%), Gaps = 24/184 (13%)

Query: 189  DEDENDKTKELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D DE +K +E+++ Q+   PR  ++    +E EV +DSL+ C  T S      D   P+ 
Sbjct: 910  DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 969

Query: 246  NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305
            +   + EE  +   L VD                  + D EEEE + P  P+++      
Sbjct: 970  SAVYSLEEQYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR----- 1008

Query: 306  KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNS 365
            +L E  E EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       
Sbjct: 1009 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 1068

Query: 366  KGEE 369
            KG++
Sbjct: 1069 KGKK 1072



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 1087 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1146

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 1147 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 1185

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 1186 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 1241



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 1256 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1315

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 1316 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 1354

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 1355 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 1410



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 1425 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1484

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 1485 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 1523

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 1524 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 1579



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 2570 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2629

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 2630 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 2668

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 2669 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 2724



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 2983 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3042

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 3043 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3081

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 3082 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3137



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 3152 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3211

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 3212 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3250

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 3251 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3306



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 3321 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3380

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 3381 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3419

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 3420 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3475



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 50/184 (27%), Positives = 82/184 (44%), Gaps = 11/184 (5%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3632 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3691

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 3692 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3749

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+  E+
Sbjct: 3750 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDGEY 3806

Query: 363  SNSK 366
             + K
Sbjct: 3807 LSMK 3810



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1980 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2039

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2040 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2097

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 2098 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2154

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2155 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2178



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3388 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3447

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 3448 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3505

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 3506 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3562

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 3563 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3586



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 497 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 556

Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
           +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 557 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 614

Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
              +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 615 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 671

Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
              + EE            +D    R+S++   LLDEK
Sbjct: 672 KYQEVEED-----------QDPSCPRLSRE---LLDEK 695



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1492 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1551

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1552 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1609

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1610 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1666

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1667 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1690



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1736 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1795

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1796 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1853

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1854 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1910

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1911 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1934



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2224 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2283

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2284 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2341

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 2342 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2398

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2399 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2422



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2637 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2696

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2697 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2754

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 2755 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2811

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2812 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2835



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 189  DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P P   RE  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1154 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1213

Query: 246  NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L    ++ +    + +   +     +   E EE + P  P+++   
Sbjct: 1214 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 1270

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +E EVLQDS +   +T     ++    QP      +L EQ +  A DV    
Sbjct: 1271 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 1328

Query: 363  SNSKGEE 369
             + + EE
Sbjct: 1329 KDQEEEE 1335



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 189  DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P P   RE  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1323 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1382

Query: 246  NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L    ++ +    + +   +     +   E EE + P  P+++   
Sbjct: 1383 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 1439

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +E EVLQDS +   +T     ++    QP      +L EQ +  A DV    
Sbjct: 1440 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 1497

Query: 363  SNSKGEE 369
             + + EE
Sbjct: 1498 KDQEEEE 1504



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 189  DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P P   RE  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3050 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3109

Query: 246  NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L    ++ +    + +   +     +   E EE + P  P+++   
Sbjct: 3110 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 3166

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +E EVLQDS +   +T     ++    QP      +L EQ +  A DV    
Sbjct: 3167 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3224

Query: 363  SNSKGEE 369
             + + EE
Sbjct: 3225 KDQEEEE 3231



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 189  DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P P   RE  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3219 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3278

Query: 246  NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L    ++ +    + +   +     +   E EE + P  P+++   
Sbjct: 3279 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 3335

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +E EVLQDS +   +T     ++    QP      +L EQ +  A DV    
Sbjct: 3336 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3393

Query: 363  SNSKGEE 369
             + + EE
Sbjct: 3394 KDQEEEE 3400



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 47/176 (26%), Positives = 74/176 (42%), Gaps = 24/176 (13%)

Query: 197 KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
           KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 843 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 902

Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
             +   L VD                E +   E EE + P  P+++      +L + +E 
Sbjct: 903 QYLGLALDVD----------------EIEKYQEVEEDQDPSCPRLS-----RELLDEKEP 941

Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
           EVLQDS +   +T     ++    QP      +L EQ +  A DV     + + EE
Sbjct: 942 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEE 997


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score =  474 bits (1221), Expect = e-134
 Identities = 249/351 (70%), Positives = 284/351 (80%), Gaps = 10/351 (2%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFRN+K++  VTQ+
Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQL 318

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           AGFLANQQ KYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL 
Sbjct: 319 AGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 379 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            D+DE+ + +  +KVQ+S APRE QKAEEKEVPEDS EECAITYSNSHGP DSN PH+  
Sbjct: 439 NDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKT 498

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
           KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 499 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 548

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
           QESEE+EV Q+S +E  +T     ++  SYQ    TF +L EQ+VC A D+
Sbjct: 549 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 599



 Score =  414 bits (1064), Expect = e-116
 Identities = 212/258 (82%), Positives = 227/258 (87%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQF N+K++  VTQ+AGFLANQQ KY Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SLN+HLQALLT D+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E +
Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KVQ+S APRE QK EE +VPEDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L
Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 261 VVDSESSQDEWQDALNIL 278
           VVD ESS DE QDALNIL
Sbjct: 241 VVDRESSHDECQDALNIL 258



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 648 ELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 708 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 751

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 752 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 806

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 892  ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 951

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 952  QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 995

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 996  TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1050

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1051 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1079



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1136 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1195

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1196 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1239

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1240 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1294

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1295 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1323



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1380 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1439

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1440 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1483

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1484 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1538

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1539 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1567



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1624 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1683

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1684 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1727

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1728 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1782

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1783 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1811



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1868 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1927

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1928 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1971

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1972 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2026

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2027 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2055



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2112 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2171

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2172 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2215

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2216 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2270

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2271 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2299



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2356 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2415

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2416 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2459

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2460 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2514

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2515 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2543



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2600 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2659

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2660 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2703

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2704 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2758

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2759 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2787



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 3351 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3410

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 3411 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3454

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 3455 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3509

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 3510 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3538



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 3595 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3654

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 3655 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3698

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 3699 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3753

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 3754 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3782



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 3839 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3898

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 3899 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3942

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 3943 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3997

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 3998 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 4026



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 4083 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 4142

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 4143 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 4186

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 4187 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 4241

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 4242 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 4270



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 4327 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 4386

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 4387 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 4430

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 4431 TKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 4485

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 4486 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 4514



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 2802 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2861

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 2862 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 2900

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 2901 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 2956



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 2971 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3030

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 3031 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3069

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 3070 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3125



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKA---EEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++    +E EV +DSL+ C  T S      D   P+ +   + EE
Sbjct: 3140 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3199

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              +   L VD                  + D EEEE + P  P+++      +L E  E 
Sbjct: 3200 QYLGLALDVD----------------RTKKDQEEEEDQGPPCPRLSR-----ELLEVVEP 3238

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T  S  +   S QP   +F AL E+ V  + DV       KG++
Sbjct: 3239 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3294



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 748 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807

Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
           +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 865

Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
              +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 866 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 922

Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
              + EE            +D    R+S++   LLDEK
Sbjct: 923 KYQEVEED-----------QDPSCPRLSRE---LLDEK 946



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1236 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1353

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1354 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1410

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1411 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1434



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1724 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1783

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1784 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1841

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1842 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1898

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1899 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1922



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1968 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2027

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2028 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2085

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 2086 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2142

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2143 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2166



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2212 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2271

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2272 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2329

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 2330 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2386

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2387 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2410



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2456 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2515

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2516 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2573

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 2574 ---ELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 2630

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2631 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2654



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3939 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3998

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 3999 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRLSR-- 4056

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 4057 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 4113

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 4114 KYQEVEED-----------QDPSCPRLSRE---LLDEK 4137



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 992  DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1109

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1110 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1166

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1167 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1190



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1480 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1539

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1540 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1597

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1598 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 1654

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1655 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1678



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3207 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3266

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 3267 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3324

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 3325 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3381

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 3382 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3405



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3451 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3510

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 3511 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3568

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 3569 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3625

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 3626 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3649



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3695 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3754

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 3755 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 3812

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 3813 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3869

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 3870 KYQEVEED-----------QDPSCPRLSRE---LLDEK 3893



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 4183 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 4242

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 4243 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 4300

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 4301 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 4357

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 4358 KYQEVEED-----------QDPSCPRLSRE---LLDEK 4381



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 49/173 (28%), Positives = 75/173 (43%), Gaps = 11/173 (6%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 4427 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 4486

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P++    
Sbjct: 4487 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLN--- 4543

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355
             G+ L E EE EVLQDS +   +T     ++  S+Q     F +  EQ +  A
Sbjct: 4544 -GV-LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 4594



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 189  DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P P   RE  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2869 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2928

Query: 246  NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L    ++ +    + +   +     +   E EE + P  P+++   
Sbjct: 2929 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 2985

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +E EVLQDS +   +T     ++    QP      +L EQ +  A DV    
Sbjct: 2986 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3043

Query: 363  SNSKGEE 369
             + + EE
Sbjct: 3044 KDQEEEE 3050



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 11/187 (5%)

Query: 189  DEDENDKTKELDKVQESPAP---REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P P   RE  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 3038 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3097

Query: 246  NIKITSEEDKVNSIL---VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L    ++ +    + +   +     +   E EE + P  P+++   
Sbjct: 3098 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS--- 3154

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +E EVLQDS +   +T     ++    QP      +L EQ +  A DV    
Sbjct: 3155 --RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTK 3212

Query: 363  SNSKGEE 369
             + + EE
Sbjct: 3213 KDQEEEE 3219


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score =  472 bits (1214), Expect = e-133
 Identities = 250/351 (71%), Positives = 283/351 (80%), Gaps = 10/351 (2%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILE+NEKLRPQLAE KQQFRN+K+K  VTQ+
Sbjct: 530 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQL 589

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           A FLANQQNKYKYEECKDLIKS+LR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL 
Sbjct: 590 ACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 649

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QLREKLREGRDAS SLNQHLQALLTPD+ D SQGQD +EQLAEGCRLA+ L  KLSPEND
Sbjct: 650 QLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPEND 709

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            D DE+ + +  +KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  
Sbjct: 710 NDHDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKT 769

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
           KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 770 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 819

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
           QESEE+EV Q+S +E  +T     ++  SYQ   GTF +L EQ+VC A D+
Sbjct: 820 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDI 870



 Score =  440 bits (1131), Expect = e-123
 Identities = 226/271 (83%), Positives = 241/271 (88%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILE+NEKLRPQLAE KQQFRN+K+K  VTQ+
Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQL 318

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           AGFLANQQNKYKYEEC+DLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL 
Sbjct: 319 AGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 378

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QLREKLREGRDAS SLNQHLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 379 QLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            DEDE+ + +E +KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNI
Sbjct: 439 EDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNI 498

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNIL 278
            IT EEDKVNS LVVD ESS DE QDA+NIL
Sbjct: 499 NITFEEDKVNSALVVDRESSHDECQDAVNIL 529



 Score =  420 bits (1079), Expect = e-117
 Identities = 215/258 (83%), Positives = 228/258 (88%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGPWSSEKAE NILEINEKLRPQLAENKQQFRN+K+K  VTQ+AGFLAN+Q KYKY
Sbjct: 1   MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SLNQHLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E +
Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNI IT EEDKVNS L
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 261 VVDSESSQDEWQDALNIL 278
           VVD ESS DE QDA+NIL
Sbjct: 241 VVDRESSHDECQDAVNIL 258



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 919  ELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 978

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+++   + EE  +   L VD                 
Sbjct: 979  QDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD----------------R 1022

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E+ E EVLQDS +   +T  S  +   S  P 
Sbjct: 1023 IKKDQEEEEDQGPPCPRLS-----RELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPY 1077

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1078 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1106



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 55/193 (28%), Positives = 81/193 (41%), Gaps = 12/193 (6%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +A E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1019 DVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYG 1078

Query: 246  NIKITSEEDKVNSILVVDSESSQDEWQDALNILL----ENQNDDEEEEGKAPVPPQVTLW 301
            +     EE  V   L V     + + +             +   E EE + P  P+++  
Sbjct: 1079 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLS-- 1136

Query: 302  ICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASE 361
              G+ L E EE EVLQDS +   +T     ++  S+Q     F +  EQ +  A DV + 
Sbjct: 1137 --GM-LMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNR 1193

Query: 362  HSNSKGEETPLGF 374
                 G    L F
Sbjct: 1194 FLTLMGTSLHLVF 1206


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score =  471 bits (1211), Expect = e-133
 Identities = 248/351 (70%), Positives = 285/351 (81%), Gaps = 10/351 (2%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+
Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           AGFLANQQNKYKYEECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL 
Sbjct: 319 AGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 379 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            D++E+ + +  +KVQ+S APRE QKAEEKEVPEDSLEECAITYSNSHGP DSN PH+  
Sbjct: 439 NDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKT 498

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
           KIT EEDKV+S L+    SS  E +DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 499 KITFEEDKVDSTLI--GSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR--------NL 548

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
           QESEE+EV Q+S +E  +T     ++  SY+    TF +L EQ+VC A D+
Sbjct: 549 QESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDI 599



 Score =  415 bits (1067), Expect = e-116
 Identities = 212/258 (82%), Positives = 229/258 (88%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQF N+K++  +TQ+AGFLAN+Q KYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E +
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KV ESPAPRE QKAEE +V EDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 261 VVDSESSQDEWQDALNIL 278
           VVD ESS DE QDALNIL
Sbjct: 241 VVDRESSHDECQDALNIL 258



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 648 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL     T S      D   P+ +   + EE  +   L +D                 
Sbjct: 708 QDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLD----------------R 751

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S+QP 
Sbjct: 752 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPY 806

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 49/173 (28%), Positives = 75/173 (43%), Gaps = 11/173 (6%)

Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 748 DLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYG 807

Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
           +     EE  V   L V   + +    + +   +     +   E EE + P  P++    
Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLN--- 864

Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355
            G+ L E EE EVLQDS +   +T     ++  S+Q     F +  EQ +  A
Sbjct: 865 -GV-LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score =  468 bits (1204), Expect = e-132
 Identities = 246/351 (70%), Positives = 283/351 (80%), Gaps = 10/351 (2%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+
Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           +GFLANQQ KYKYEECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL 
Sbjct: 319 SGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QL+EKLREGRDAS SLN+HLQALLTP + D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 379 QLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            D+DE+ + +  +KVQ+S APRE QKAEEKEVPEDSLEECAITYSNSHG  DSN PH+  
Sbjct: 439 NDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKT 498

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
           KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 499 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 548

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
           QESEE+EV Q+S +E  +T     ++  SYQ    TF +L EQ+VC A D+
Sbjct: 549 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 599



 Score =  414 bits (1063), Expect = e-115
 Identities = 212/258 (82%), Positives = 227/258 (87%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGPWSSEKAEMNILEINE LRPQLAE KQQFRN+K+K  +TQ+AGFLAN+Q KYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SL +HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E +
Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 261 VVDSESSQDEWQDALNIL 278
           VVD ESS DE QDALNIL
Sbjct: 241 VVDRESSHDECQDALNIL 258



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2602 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2661

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2662 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2705

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2706 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2789



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2846 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2905

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2906 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2949

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2950 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3004

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 3005 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3033



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 892  ELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 951

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 952  QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 995

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 996  IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1050

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1051 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1079



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1626 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1685

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1686 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1729

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1730 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1784

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E  V  + DV       KG++
Sbjct: 1785 GSSFYALEENHVGFSLDVGEIEKKGKGKK 1813



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1870 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1929

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1930 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1973

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1974 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2028

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E  V  + DV       KG++
Sbjct: 2029 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2057



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2114 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2173

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2174 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2217

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2218 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2272

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E  V  + DV       KG++
Sbjct: 2273 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2301



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 2358 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2417

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 2418 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2461

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 2462 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2516

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E  V  + DV       KG++
Sbjct: 2517 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2545



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 3165 ELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3224

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 3225 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3268

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 3269 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3323

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 3324 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3352



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 648 ELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 708 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 751

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 752 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 806

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 56/209 (26%), Positives = 92/209 (44%), Gaps = 25/209 (11%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1380 ELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1439

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL  C  T S      D   P+ +   + EE  +   L VD               ++
Sbjct: 1440 QDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR--------------IK 1485

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
               ++EE+E + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 1486 KDQEEEEDEDQDPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1540

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E  V  + DV       KG++
Sbjct: 1541 GSSFYALEENHVGFSLDVGEIEKKGKGKK 1569



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 57/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 1136 ELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1195

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 1196 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1239

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             + D+EEEE + P  P+++      +L E    EVLQDS +   +T  S  +   S QP 
Sbjct: 1240 IKKDEEEEEDQDPPCPRLSR-----ELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1294

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
              +F AL E+ V  + DV       KG++
Sbjct: 1295 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1323



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 59/220 (26%), Positives = 96/220 (43%), Gaps = 25/220 (11%)

Query: 187  DTDEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPP 243
            D D  + D+ +E D+ Q+ P PR   E  +  E EV +DSL+ C  T S+     DS  P
Sbjct: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539

Query: 244  HKNIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300
            + +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++ 
Sbjct: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599

Query: 301  WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360
                 +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+  
Sbjct: 1600 -----ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDE 1654

Query: 361  EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
                 + EE            +D    R+S++   LLDEK
Sbjct: 1655 IEKYQEVEED-----------QDPSCPRLSRE---LLDEK 1680



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 49/195 (25%), Positives = 87/195 (44%), Gaps = 8/195 (4%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 3409 ELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3468

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      D   P+ +   + EE  +   L VD    + + +       +
Sbjct: 3469 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSK 3528

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             +     +EG+    P     + G+ L E EE+EVLQDS +   +T     ++  S+Q  
Sbjct: 3529 KERRRGRKEGEEDQNPPCPR-LNGV-LMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHY 3586

Query: 341  EGTFLALVEQKVCSA 355
               F +  EQ +  A
Sbjct: 3587 RSVFYSFEEQHISFA 3601



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 55/209 (26%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPR-EEQKAEEK--EVP 220
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR   +  +EK  EV 
Sbjct: 3090 ELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVL 3149

Query: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
            +DSL+ C  T S      DS  P+++     E+ +V   L VD +              E
Sbjct: 3150 QDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVG--LAVDMD--------------E 3193

Query: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
             +   E EE + P  P+++      +L + +E EVLQDS +   +T     ++    QP 
Sbjct: 3194 IEKYQEVEEDQDPSCPRLS-----RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 3248

Query: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
                 +L EQ +  A DV     + + EE
Sbjct: 3249 SSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q+ P PR  ++  E   PE   DSL+ C  T S+     DS  P+ 
Sbjct: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1353

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1354 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIE 1410

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1411 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1434



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 748 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807

Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
           +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 865

Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
              +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 866 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIE 922

Query: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
              + EE            +D    R+S++   LLDEK
Sbjct: 923 KYQEVEED-----------QDPSCPRLSRE---LLDEK 946



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 992  DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1109

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 1110 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIE 1166

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1167 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1190



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1843

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 1844 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 1900

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 1901 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1924



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2087

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 2088 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2144

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2145 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2168



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2331

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 2332 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2388

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2389 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2412



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2575

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 2576 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2632

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2633 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2656



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 58/218 (26%), Positives = 92/218 (42%), Gaps = 25/218 (11%)

Query: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761

Query: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2819

Query: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 2820 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2876

Query: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400
               + EE            +D    R+S++   LLDEK
Sbjct: 2877 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2900



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 54/207 (26%), Positives = 89/207 (42%), Gaps = 38/207 (18%)

Query: 197  KELDKVQESPAPREEQKAEEKEVP---EDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++  +++ P   +DSL+ C  T S      DS  P+++     E+
Sbjct: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
             +V   L VD +              E +   E EE + P  P+++      +L + +  
Sbjct: 3108 QRVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSR-----ELLDEKGP 3146

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLG 373
            EVLQDS +   +T     ++  S QP    F  L +Q+V  A D+       + EE    
Sbjct: 3147 EVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEED--- 3203

Query: 374  FPDTKYCWKDEKDERMSQKVAFLLDEK 400
                    +D    R+S++   LLDEK
Sbjct: 3204 --------QDPSCPRLSRE---LLDEK 3219



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 24/176 (13%)

Query: 197  KELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR  ++  +++ PE   DSL+ C  T S      DS  P+++     E+
Sbjct: 3367 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3426

Query: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
              V   L VD +              E +   E EE + P  P+++      +L + +E 
Sbjct: 3427 QHVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSR-----ELLDEKEP 3465

Query: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T     ++    QP      +L EQ +  A DV       KG++
Sbjct: 3466 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKK 3521



 Score = 35.4 bits (80), Expect = 0.098
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 197  KELDKVQESPAPREE---QKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            KE ++ Q  P PR      + EE+EV +DSL+ C  T S      DS   ++++  + EE
Sbjct: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595

Query: 254  DKVNSILVVDS 264
              ++  L VD+
Sbjct: 3596 QHISFALYVDN 3606


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score =  467 bits (1202), Expect = e-132
 Identities = 255/385 (66%), Positives = 292/385 (75%), Gaps = 11/385 (2%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFR++K+K  VTQ+
Sbjct: 184 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQV 243

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           A FLA QQNKYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL 
Sbjct: 244 ACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 303

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 304 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 363

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            D+DE+ + +  +KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  
Sbjct: 364 NDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKT 423

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
           KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 424 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 473

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSK 366
           QESEE+EV Q+S +E  +T     +   SYQ    TF +L EQ+VC A D+        K
Sbjct: 474 QESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVK 533

Query: 367 GEETPLGFPDTKYCWKDEKDERMSQ 391
            E+     P       DEK+  + Q
Sbjct: 534 KEDQEATGPRLSRELLDEKEPEVLQ 558



 Score =  258 bits (660), Expect = 5e-69
 Identities = 133/169 (78%), Positives = 145/169 (85%)

Query: 110 EELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLA 169
           +E++QYKVLVHSQEREL QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 170 EGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAI 229
           EGCRLA+HLV KLSPEND DEDE+ + +E +KV ES APRE QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 230 TYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNIL 278
           T SNSHGP DS  PHKNIKIT EEDKVNS LVVD ESS D  QDALNIL
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNIL 183



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 27/158 (17%)

Query: 168 LAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAP---REEQKAEEKEVPE 221
           L + C+  R   + L  +      D DE +K +E+++ Q+   P   RE    +E EV +
Sbjct: 574 LTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQ 633

Query: 222 DSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLEN 281
           DSL+ C  T S      D   P+++   + EE  +   L VD                  
Sbjct: 634 DSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD----------------RI 677

Query: 282 QNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDS 319
           + D EEEE + P  P+++      +L E  E EVLQDS
Sbjct: 678 KKDQEEEEDQGPPCPRLS-----RELLEVVEPEVLQDS 710



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 22/177 (12%)

Query: 194 DKTKELDKVQESPA-PREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSE 252
           D+ K+ D+    P   RE    +E EV +DSL+ C  T S   G +DS  P+++     E
Sbjct: 530 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLE 589

Query: 253 EDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEE 312
           + ++   L VD +              E +   E EE + P  P+++      +L   +E
Sbjct: 590 QQRIG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLS-----RELLAEKE 628

Query: 313 KEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T     ++    QP      +L EQ +  A DV     + + EE
Sbjct: 629 PEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 685


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score =  467 bits (1202), Expect = e-132
 Identities = 255/385 (66%), Positives = 292/385 (75%), Gaps = 11/385 (2%)

Query: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKL PQLAE KQQFR++K+K  VTQ+
Sbjct: 184 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQV 243

Query: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127
           A FLA QQNKYKYEECKDLIKSMLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL 
Sbjct: 244 ACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT 303

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 304 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 363

Query: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
            D+DE+ + +  +KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  
Sbjct: 364 NDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKT 423

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
           KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 424 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 473

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSK 366
           QESEE+EV Q+S +E  +T     +   SYQ    TF +L EQ+VC A D+        K
Sbjct: 474 QESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVK 533

Query: 367 GEETPLGFPDTKYCWKDEKDERMSQ 391
            E+     P       DEK+  + Q
Sbjct: 534 KEDQEATGPRLSRELLDEKEPEVLQ 558



 Score =  259 bits (663), Expect = 2e-69
 Identities = 134/169 (79%), Positives = 145/169 (85%)

Query: 110 EELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLA 169
           EE++QYKVLVHSQEREL QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 170 EGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAI 229
           EGCRLA+HLV KLSPEND DEDE+ + +E +KV ES APRE QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 230 TYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNIL 278
           T SNSHGP DS  PHKNIKIT EEDKVNS LVVD ESS D  QDALNIL
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNIL 183



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 27/158 (17%)

Query: 168 LAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAP---REEQKAEEKEVPE 221
           L + C+  R   + L  +      D DE +K +E+++ Q+   P   RE    +E EV +
Sbjct: 574 LTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQ 633

Query: 222 DSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLEN 281
           DSL+ C  T S      D   P+++   + EE  +   L VD                  
Sbjct: 634 DSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD----------------RI 677

Query: 282 QNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDS 319
           + D EEEE + P  P+++      +L E  E EVLQDS
Sbjct: 678 KKDQEEEEDQGPPCPRLS-----RELLEVVEPEVLQDS 710



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 22/177 (12%)

Query: 194 DKTKELDKVQESPA-PREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSE 252
           D+ K+ D+    P   RE    +E EV +DSL+ C  T S   G +DS  P+++     E
Sbjct: 530 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLE 589

Query: 253 EDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEE 312
           + ++   L VD +              E +   E EE + P  P+++      +L   +E
Sbjct: 590 QQRIG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLS-----RELLAEKE 628

Query: 313 KEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369
            EVLQDS +   +T     ++    QP      +L EQ +  A DV     + + EE
Sbjct: 629 PEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 685


>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score =  451 bits (1159), Expect = e-127
 Identities = 244/372 (65%), Positives = 281/372 (75%), Gaps = 11/372 (2%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+AGFLAN+Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRL +HLV KLSPEND D+DE+ + +  +
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PHK  KIT EEDKV+S L
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320
           +    SS  EW+DA++I+ EN++DDEEEE K PV P+         LQESEE+EV Q+S 
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESW 290

Query: 321 EERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSKGEETPLGFPDTKY 379
           +E  +T     ++  SYQ    TF +L EQ+VC A D+        K E+     P    
Sbjct: 291 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 350

Query: 380 CWKDEKDERMSQ 391
              DEK+  + Q
Sbjct: 351 ELLDEKEPEVLQ 362



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 377 ELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 436

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL+ C  T S+     D   P+ +   + EE  +   L VD                 
Sbjct: 437 QDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVD----------------R 480

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 481 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 564



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 6/168 (3%)

Query: 191 DENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247
           D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ + 
Sbjct: 479 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538

Query: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307
               EE  V   L V     + + +       + +     +EG+   PP   L+  G+ L
Sbjct: 539 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLY--GV-L 595

Query: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355
            E EE EVLQDS +   +T     +   S+Q     F +  E+ +  A
Sbjct: 596 MEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFA 643



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 17/52 (32%), Positives = 29/52 (55%)

Query: 213 KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDS 264
           + EE EV +DSL+ C  T S      DS   ++++  + EE+ ++  L VD+
Sbjct: 597 EVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDN 648


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score =  451 bits (1159), Expect = e-127
 Identities = 244/372 (65%), Positives = 281/372 (75%), Gaps = 11/372 (2%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+AGFLAN+Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRL +HLV KLSPEND D+DE+ + +  +
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PHK  KIT EEDKV+S L
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320
           +    SS  EW+DA++I+ EN++DDEEEE K PV P+         LQESEE+EV Q+S 
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESW 290

Query: 321 EERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSKGEETPLGFPDTKY 379
           +E  +T     ++  SYQ    TF +L EQ+VC A D+        K E+     P    
Sbjct: 291 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 350

Query: 380 CWKDEKDERMSQ 391
              DEK+  + Q
Sbjct: 351 ELLDEKEPEVLQ 362



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 377 ELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 436

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL+ C  T S+     D   P+ +   + EE  +   L VD                 
Sbjct: 437 QDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 480

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 481 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 564



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 47/170 (27%), Positives = 71/170 (41%), Gaps = 6/170 (3%)

Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 477 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536

Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305
           +     EE  V   L V     + + +       + +     +EG+   PP   L     
Sbjct: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRL---NG 593

Query: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355
            L E EE EVLQDS +   +T     ++  S+Q     F +  E+ +  A
Sbjct: 594 VLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFA 643



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 206 PAPREE---QKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVV 262
           P PR      + EE EV +DSL+ C  T S      DS   ++++  + EE+ ++  L V
Sbjct: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646

Query: 263 DS 264
           D+
Sbjct: 647 DN 648


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score =  449 bits (1156), Expect = e-126
 Identities = 248/384 (64%), Positives = 287/384 (74%), Gaps = 11/384 (2%)

Query: 9   VPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMA 68
           VPG TSSATNV+MVVSAGPWS EKAEMNILEIN+K RPQLAENKQQFRN+KQK LVTQ+A
Sbjct: 45  VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVA 104

Query: 69  GFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQ 128
            FLAN+QN Y YE+CKDLIKSMLR+E    EEKLAE+L QAEELRQYKVLVHSQEREL Q
Sbjct: 105 YFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQ 164

Query: 129 LREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDT 188
           LREKL+EGRDAS SLNQHLQALLTPD+ DNSQG+D REQLAEGCRLA+HLV KLSPEND 
Sbjct: 165 LREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD 224

Query: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248
           DEDE+ K +E +KVQE  APRE QKAEEKEVPEDSLEECAIT SNSH P +SN P+ N +
Sbjct: 225 DEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTR 284

Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308
           IT EED+V+S L+    SS DEW DA+ I+ EN++D E+EE K PV P+         LQ
Sbjct: 285 ITFEEDQVDSTLI--DSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR--------NLQ 334

Query: 309 ESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNS-KG 367
           ESEE+E  Q+S +E   T     D+S SYQ    TF ++ EQ+V  A D+     +  K 
Sbjct: 335 ESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKK 394

Query: 368 EETPLGFPDTKYCWKDEKDERMSQ 391
           E+     P       DEK+  + Q
Sbjct: 395 EDQEATSPRLSRELLDEKEPEVLQ 418



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 24/173 (13%)

Query: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPS---DSNPPHK 245
           D D   K +E ++ Q  P PR  ++  E   PED  +     YS         DS  P+ 
Sbjct: 458 DLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYG 517

Query: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305
           +   + EE+ V   L VD               +E   + EE++ K P P    +     
Sbjct: 518 SCFYSLEEEHVGFSLDVDE--------------IEKYQEGEEDQ-KPPCPRLNEV----- 557

Query: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
            L E+EE EVLQDS +   +T+ +   +  S+Q     F +  EQ V  A DV
Sbjct: 558 -LMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 6/104 (5%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVP 220
           +L + C+      + L  E+     D DE +K +E ++ Q+ P PR  +   +AEE EV 
Sbjct: 508 ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDS 264
           +DSL+ C  T S       S   +++   + EE  V+  L VD+
Sbjct: 568 QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDN 611


>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  424 bits (1091), Expect = e-119
 Identities = 216/280 (77%), Positives = 243/280 (86%), Gaps = 2/280 (0%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFR++K+K  VTQ+AGFLA QQNKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           EECKDLIKSMLR ELQFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND D+DE+ + +  +
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260
           KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  KIT EEDKV+S L
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300
           +    SS  EW+DA++I+ EN++DDEEEE K PV P+ ++
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSV 278


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  424 bits (1089), Expect = e-118
 Identities = 242/402 (60%), Positives = 290/402 (72%), Gaps = 16/402 (3%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ   + LANQ  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EE KD+I S+LR+ELQ   EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197
           S  LN+HL+ LLTPD  D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+  DK +
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257
           E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317
           S LVV+SE   DE ++ALNI  ENQND EEEEGKAPVPP+        +  E  E   L+
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR------NRQSLEPGELTNLR 293

Query: 318 D---SPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGF 374
           D   SP      +   HD S SY+  E +FLAL EQKVCSAQDVA ++SN K +ET LGF
Sbjct: 294 DFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGF 353

Query: 375 PDTKYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416
            + +    D ++ +  + VA  L           IP  +L G
Sbjct: 354 LEKQ---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 392



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 55/172 (31%), Positives = 89/172 (51%), Gaps = 27/172 (15%)

Query: 194 DKTKELDKV--QESPAPREEQ---KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248
           +K  +L++V  QE+ APR  +   + ++ E+P++SL+ C +T S     + S  P+ +  
Sbjct: 355 EKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWST- 413

Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308
           + S EDK  S+ +VD                + + D EE E ++P  P+++      +L 
Sbjct: 414 LYSFEDKQVSLALVD----------------KIKKDQEEIEDQSPPCPRLSQ-----ELP 452

Query: 309 ESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360
           E +E+EV +DS  E   T    HDVS  +QP   T  +L +Q  CSA DVAS
Sbjct: 453 EVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVAS 504


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  416 bits (1069), Expect = e-116
 Identities = 236/399 (59%), Positives = 281/399 (70%), Gaps = 39/399 (9%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ   + LANQ  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EE KD+I S+LR+ELQ   EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197
           S  LN+HL+ LLTPD  D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+  DK +
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257
           E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317
           S LVV+SE   DE ++ALNI  ENQND EEEEGKAPVPP+                    
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-------------------- 279

Query: 318 DSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDT 377
                        HD S SY+  E +FLAL EQKVCSAQDVA ++SN K +ET LGF + 
Sbjct: 280 ------------HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEK 327

Query: 378 KYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416
           +    D ++ +  + VA  L           IP  +L G
Sbjct: 328 Q---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 363



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 39/253 (15%)

Query: 120 HSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFRE---------QLAE 170
           H +E E + +  + +   +         +A + P  HD S     RE         ++  
Sbjct: 250 HDEEEEALNIPPENQNDHEEEEG-----KAPVPPRHHDKSNSYRHREVSFLALDEQKVCS 304

Query: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVPEDSLEEC 227
              +AR   +    E      E     E  K QE+ APR  +   + ++ E+P++SL+ C
Sbjct: 305 AQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGC 364

Query: 228 AITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEE 287
            +T S     + S  P+ +  + S EDK  S+ +VD                + + D EE
Sbjct: 365 CLTPSILPDLTPSYHPYWST-LYSFEDKQVSLALVD----------------KIKKDQEE 407

Query: 288 EEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLAL 347
            E ++P  P+++      +L E +E+EV +DS  E   T    HDVS  +QP   T  +L
Sbjct: 408 IEDQSPPCPRLSQ-----ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSL 462

Query: 348 VEQKVCSAQDVAS 360
            +Q  CSA DVAS
Sbjct: 463 EDQLACSALDVAS 475


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  416 bits (1069), Expect = e-116
 Identities = 236/399 (59%), Positives = 281/399 (70%), Gaps = 39/399 (9%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ   + LANQ  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EE KD+I S+LR+ELQ   EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197
           S  LN+HL+ LLTPD  D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+  DK +
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257
           E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317
           S LVV+SE   DE ++ALNI  ENQND EEEEGKAPVPP+                    
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-------------------- 279

Query: 318 DSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDT 377
                        HD S SY+  E +FLAL EQKVCSAQDVA ++SN K +ET LGF + 
Sbjct: 280 ------------HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEK 327

Query: 378 KYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416
           +    D ++ +  + VA  L           IP  +L G
Sbjct: 328 Q---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 363



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 39/253 (15%)

Query: 120 HSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFRE---------QLAE 170
           H +E E + +  + +   +         +A + P  HD S     RE         ++  
Sbjct: 250 HDEEEEALNIPPENQNDHEEEEG-----KAPVPPRHHDKSNSYRHREVSFLALDEQKVCS 304

Query: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVPEDSLEEC 227
              +AR   +    E      E     E  K QE+ APR  +   + ++ E+P++SL+ C
Sbjct: 305 AQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGC 364

Query: 228 AITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEE 287
            +T S     + S  P+ +  + S EDK  S+ +VD                + + D EE
Sbjct: 365 CLTPSILPDLTPSYHPYWST-LYSFEDKQVSLALVD----------------KIKKDQEE 407

Query: 288 EEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLAL 347
            E ++P  P+++      +L E +E+EV +DS  E   T    HDVS  +QP   T  +L
Sbjct: 408 IEDQSPPCPRLSQ-----ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSL 462

Query: 348 VEQKVCSAQDVAS 360
            +Q  CSA DVAS
Sbjct: 463 EDQLACSALDVAS 475


>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score =  335 bits (859), Expect = 5e-92
 Identities = 178/269 (66%), Positives = 209/269 (77%), Gaps = 10/269 (3%)

Query: 90  MLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQA 149
           MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS SLN+HLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 150 LLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPR 209
           LLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND D+DE+ + +  +KVQ+S APR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 210 EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQD 269
           E QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  KIT EEDKV+S L+    SS  
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178

Query: 270 EWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCS 329
           EW+DA++I+ EN++DDEEEE K PV P+         LQESEE+EV Q+S +E  +T   
Sbjct: 179 EWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESWDEGYSTLSI 230

Query: 330 DHDVSQSYQPCEGTFLALVEQKVCSAQDV 358
             ++  SY+    TF +L EQ+VC A D+
Sbjct: 231 PPEMLASYKSYSSTFHSLEEQQVCMAVDI 259



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 627 ELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 686

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL  C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 687 QDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 730

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 731 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 785

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 786 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 814



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220
           +L + C+  R   + L  +      + DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 308 ELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 367

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           +DSL  C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 368 QDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 411

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 412 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 466

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
             +F AL E+ V  + DV       KG++
Sbjct: 467 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 495



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 54/209 (25%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPR---EEQKAEEKEVP 220
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR   E    +E EV 
Sbjct: 552 ELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVL 611

Query: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280
           ++SL+ C  T S     +DS  P+++     E+ +V   L VD +              E
Sbjct: 612 QESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVG--LAVDMD--------------E 655

Query: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340
            +   E EE + P  P+++      +L + +E EVLQDS     +T     ++    QP 
Sbjct: 656 IEKYQEVEEDQDPSCPRLS-----RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPY 710

Query: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369
                +L EQ +  A DV     + + EE
Sbjct: 711 SSAVYSLEEQYLGLALDVDRIKKDQEEEE 739



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 38/207 (18%)

Query: 197 KELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
           KE ++ Q  P PR  ++  +++ PE   DSL+ C  T S     +DS  P+++     E+
Sbjct: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569

Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
            +V   L VD +              E +   E EE + P  P+++      +L + +E 
Sbjct: 570 QRVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSG-----ELLDEKEP 608

Query: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLG 373
           EVLQ+S +   +T     +++ S QP    F  L +Q+V  A D+       + EE    
Sbjct: 609 EVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEED--- 665

Query: 374 FPDTKYCWKDEKDERMSQKVAFLLDEK 400
                   +D    R+S++   LLDEK
Sbjct: 666 --------QDPSCPRLSRE---LLDEK 681



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 11/173 (6%)

Query: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 727 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 786

Query: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302
           +     EE  V   L V   + +    + +   +     +   E EE + P  P++    
Sbjct: 787 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSM- 845

Query: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355
               L E EE EVLQDS +   +T     ++  S+Q     F +  E+ +  A
Sbjct: 846 ----LMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFA 894



 Score = 33.9 bits (76), Expect = 0.28
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 197 KELDKVQESPAPREEQ---KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
           KE ++ Q  P PR      + EE EV +DSL+ C  T S      DS   ++++  + EE
Sbjct: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888

Query: 254 DKVNSILVVDS 264
           + ++  L VD+
Sbjct: 889 EHISFALYVDN 899


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  127 bits (320), Expect = 1e-29
 Identities = 79/199 (39%), Positives = 112/199 (56%), Gaps = 15/199 (7%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           M VSA      +AEM+ILE N+ LR +L + KQ F+++ +KFL ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EECKDLI+S+L EE+QF+E +LAE  + A  LR +  L+ +Q  EL  LR+K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192
            +   QH+       + LL        Q Q F EQ+ +G +L   LV KL+ EN   +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 193 NDKTKELDKVQESPAPREE 211
            D+ K L       APR E
Sbjct: 181 EDRQKPL-------APRSE 192


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  125 bits (313), Expect = 9e-29
 Identities = 78/199 (39%), Positives = 111/199 (55%), Gaps = 15/199 (7%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           M VSA      +AE++ILE N+ LR +L + KQ F+++ +KFL ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EECKDLI+S+L EE+QF+E +LAE  + A  LR +  L+ +Q  EL  LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192
            +   QH+       + LL        Q Q F EQ+ +G +L   LV KL+ EN   +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 193 NDKTKELDKVQESPAPREE 211
            D+ K L       APR E
Sbjct: 181 EDRQKPL-------APRSE 192


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score =  125 bits (313), Expect = 9e-29
 Identities = 78/199 (39%), Positives = 111/199 (55%), Gaps = 15/199 (7%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           M VSA      +AE++ILE N+ LR +L + KQ F+++ +KFL ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EECKDLI+S+L EE+QF+E +LAE  + A  LR +  L+ +Q  EL  LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192
            +   QH+       + LL        Q Q F EQ+ +G +L   LV KL+ EN   +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 193 NDKTKELDKVQESPAPREE 211
            D+ K L       APR E
Sbjct: 181 EDRQKPL-------APRSE 192


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score =  123 bits (309), Expect = 3e-28
 Identities = 78/199 (39%), Positives = 110/199 (55%), Gaps = 15/199 (7%)

Query: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79
           M VSA      +AE++ILE N+ LR +L + KQ F+++ +KFL ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 80  YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139
            EECKDLI+S+L EE+QF+E +LAE  + A  LR +  L+ +Q  EL  LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 140 SHSLNQHL-------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDE 192
            +   QH+       + LL        Q Q F EQ+ +G +L   LV KL  EN   +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 193 NDKTKELDKVQESPAPREE 211
            D+ K L       APR E
Sbjct: 181 EDRQKPL-------APRSE 192


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 66/209 (31%), Positives = 105/209 (50%), Gaps = 22/209 (10%)

Query: 81   EECKDLIKSMLREELQFK----EEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREG 136
            ++ + LI+ + + E Q      EEKLAE+L+ A    +Y  L+  Q REL  LR+K+REG
Sbjct: 1436 KDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREG 1495

Query: 137  RDASHSLNQH-------LQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTD 189
            R   + + +H        + LL  +  D   GQ FREQLA+G +L   L  KLS ++   
Sbjct: 1496 RGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS 1555

Query: 190  EDENDKTKELDKVQESPAPREEQKAEEK----EVPEDSLEECAITYSNSHGPSDSNPPHK 245
            E +    + L       A R  ++ +EK    EV +  L+  ++T S+SH  SDS+    
Sbjct: 1556 EKDQAGLEPL-------ALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPS 1608

Query: 246  NIKITSEEDKVNSILVVDSESSQDEWQDA 274
            +    S+E +  S + + SE +  E + A
Sbjct: 1609 STSFLSDELEACSDMDIVSEYTHYEEKKA 1637



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 57/279 (20%), Positives = 114/279 (40%), Gaps = 51/279 (18%)

Query: 28  WSSEK------AEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYE 81
           W +EK       E NI  +N  L      +K+Q        L+ +    L  + N  K  
Sbjct: 421 WEAEKYNEIRTQEQNIQHLNHSL-----SHKEQ--------LLQEFRELLQYRDNSDKTL 467

Query: 82  ECKDLIKSMLREELQFK--------EEKLAEQLKQAEELRQYKVLVHSQERELIQLREKL 133
           E  +++   LR+ +  K        +EK +   ++ +ELRQ ++ V  ++ +L    E+L
Sbjct: 468 EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDL----ERL 523

Query: 134 REGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN 193
           R+   ++ +  Q +++LL       ++G +  EQL+  C+  + L           E+  
Sbjct: 524 RDVLSSNEATMQSMESLL------RAKGLEV-EQLSTTCQNLQWL----------KEEME 566

Query: 194 DKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253
            K     K QES   + +    ++      +E+ + T     GP  S    +  +    +
Sbjct: 567 TKFSRWQKEQESIIQQLQTSLHDR---NKEVEDLSATLLCKLGPGQSEIAEELCQRLQRK 623

Query: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKA 292
           +++   L+ D      E +  +  LL++ +  E+E   A
Sbjct: 624 ERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAA 662



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 85/422 (20%), Positives = 154/422 (36%), Gaps = 103/422 (24%)

Query: 42   EKLRPQLAENKQQFRNMKQKFLVTQMAGFL-ANQQNKYK--------------------- 79
            + LR QL++ KQ+++++++K L+++   F  AN+  KY+                     
Sbjct: 1214 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 1273

Query: 80   ---YEECKDLIKSMLREELQFKEEKLAEQLKQ--------AEELRQYKVLVHSQERE--- 125
               YE C        REE    E +    LK+        +E+ R+   L  S ER+   
Sbjct: 1274 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 1333

Query: 126  -----------------LIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQL 168
                             ++ LR+ +++ +    + N+ +Q L +  +   S   D+   L
Sbjct: 1334 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVR-SLSVTSDYSSSL 1392

Query: 169  AEGCRL-ARHLVHKLSPENDTDEDEN------------------DKTKELDKVQESPAPR 209
                +L A   +   SP +  DEDE                   D    + +V +  A  
Sbjct: 1393 ERPWKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQL 1452

Query: 210  EEQKAEEKEVPE----------DSL----------------EECAITYSNSHGPSDSNPP 243
             +   EEK   E          DSL                E   I Y  +    D+   
Sbjct: 1453 PKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKS 1512

Query: 244  HKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWIC 303
             +++  +++ D        +  +   +  + L   L  ++   E++     P  + L   
Sbjct: 1513 FEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRL--- 1569

Query: 304  GLKLQESEEK-EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362
              +LQE E+  EVLQ   + R  T  S H +S S++    T     E + CS  D+ SE+
Sbjct: 1570 SRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEY 1629

Query: 363  SN 364
            ++
Sbjct: 1630 TH 1631



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 53/233 (22%), Positives = 87/233 (37%), Gaps = 33/233 (14%)

Query: 9    VPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAEN---KQQFRNMKQKFLVT 65
            V G  SS ++V  + S  P  ++  E ++ EI   LR +L E+     + R   +  L +
Sbjct: 1821 VSGDLSSGSSVYQLNSK-PTGADLLEEHLGEIRN-LRQRLEESICINDRLREQLEHRLTS 1878

Query: 66   QMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERE 125
               G          Y +  + I  +  E    +E+    Q + +   R+     HSQE E
Sbjct: 1879 TARG---RGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSRE-----HSQETE 1930

Query: 126  LIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPE 185
             +         R+A  S   HLQ L    +H   + Q   E L E  +   H        
Sbjct: 1931 SL---------REALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHF------- 1974

Query: 186  NDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPS 238
                 +E    +E D   +      +Q+ EEK+   +SL+     Y   +G S
Sbjct: 1975 ----REERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNS 2023


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 70/327 (21%), Positives = 134/327 (40%), Gaps = 44/327 (13%)

Query: 52  KQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLA-EQLKQAE 110
           ++Q R  K++    + A  L        Y   K +IK     E Q ++++LA +Q+++A+
Sbjct: 366 EEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425

Query: 111 ELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAE 170
           +LR+++  +H Q  +   LR++ ++ +  +  +    QA L   +  +      +EQL  
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQH------QEQL-- 477

Query: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAIT 230
                R   H  + +ND  +   D+  +    +E    R+ Q  +E E            
Sbjct: 478 -----RQQAHYDAMDNDIVQGAEDQGIQ---GEEGAYERDNQHQDEAEGDP--------- 520

Query: 231 YSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQ--DEWQDALNILLENQNDDEEE 288
             N H P +  P   + +  ++   V  I   D  ++Q  DE+++A  +  EN  D+ EE
Sbjct: 521 -GNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579

Query: 289 EGKAPVPPQVT-----LWICG-LKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEG 342
           + ++    + T     L + G    QE    E  Q+  EE V    ++    +     E 
Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639

Query: 343 TFLALVEQKVCSAQDVASEHSNSKGEE 369
           T+            D  ++  N+ GEE
Sbjct: 640 TY---------GENDENTDDKNNDGEE 657



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 18/130 (13%)

Query: 104 EQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQD 163
           ++ ++AE++R+  +   ++E++    +++  E       + +HL     PD+ +++  + 
Sbjct: 560 DEFEEAEQVREENLPDENEEQKQSNQKQENTE-------VEEHLVMAGNPDQQEDNVDEQ 612

Query: 164 FREQLAEGC---------RLARHLVHKLSPEND--TDEDENDKTKELDKVQESPAPREEQ 212
           ++E+  E           R   H   +   END  TD+  ND  ++  +    P  REE 
Sbjct: 613 YQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEH 672

Query: 213 KAEEKEVPED 222
             EE+E  ED
Sbjct: 673 YEEEEEEEED 682


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 53/276 (19%), Positives = 119/276 (43%), Gaps = 31/276 (11%)

Query: 42  EKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFKEE- 100
           EK+R Q    +Q+ +  +Q+  + +    +  Q+ K   +E K   +  +REE + +E+ 
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523

Query: 101 ---KLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHD 157
              +  E++++ EE+ + K  +H QE ++ +  EK+    +  H   + ++     ++ +
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR-----EQEE 578

Query: 158 NSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEK 217
               Q+  E++ E     R    K+  + +  +++ +K  E    QE     +E+K +E+
Sbjct: 579 KVWRQE--EKIREQEEKIREQEEKIREQEEMTQEQEEKMGE----QEEKMCEQEEKMQEQ 632

Query: 218 EVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNI 277
           E      EE                  +  KI  +E+K+     +  E  +  W+    +
Sbjct: 633 EEKMRRQEE--------------KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 678

Query: 278 LLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
             + +   E+EE       +  +W   ++L++ EEK
Sbjct: 679 CEQEEKMQEQEEKMR--RQEEKMWEQEVRLRQQEEK 712



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 75/382 (19%), Positives = 154/382 (40%), Gaps = 59/382 (15%)

Query: 30  SEKAE--MNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLI 87
           SEK+E  +N+ E+  KL        QQ    +   L  ++    A  Q + +  E  + +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355

Query: 88  KSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHL 147
                E++  +EEK+ E     E++++ +  +  QE ++ +  EK+R   +      + +
Sbjct: 356 NQQQEEKMWRQEEKIQEW---EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412

Query: 148 --QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSP-----ENDTDEDENDKTKELD 200
             Q  +  +K +  + Q+  E + E     R L  K+       E +    E +K +E +
Sbjct: 413 RRQEEMMWEKEEKMRRQE--EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470

Query: 201 KVQESPAP--REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNS 258
           K QE  A   R+E+K  E+E      EE                     K+  +E+K++ 
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEE---------------------KMWRQEEKIHE 509

Query: 259 ILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQD 318
              +  E  + E ++   +  + +   E+EE          +W    K+ E EEK  ++ 
Sbjct: 510 QEKIREEEKRQEQEE---MWRQEEKIREQEE----------IWRQKEKIHEQEEK--IRK 554

Query: 319 SPEERVTTSCSDHDVSQSYQPCEGTF------LALVEQKVCSAQD-VASEHSNSKGEETP 371
             E+        HD  +  +  E         +   E+K+   ++ +  +   ++ +E  
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614

Query: 372 LGFPDTKYCWKDEKDERMSQKV 393
           +G  + K C ++EK +   +K+
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKM 636



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 74/334 (22%), Positives = 128/334 (38%), Gaps = 49/334 (14%)

Query: 14  SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73
           ++ TN     S G  S E  +    +  E LR +L       R +  +    QMA + + 
Sbjct: 152 NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ 211

Query: 74  QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122
              K    E +DLI S L +  +F  E       +A Q K+A    EEL + +  +  + 
Sbjct: 212 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 270

Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173
                 + EL +   KL+E      S    +Q  +   K    + +    ++QL AE   
Sbjct: 271 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 330

Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSN 233
           L + L   +S +     +EN+    L++ QE    R+E+K +E E      EE       
Sbjct: 331 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE------- 382

Query: 234 SHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAP 293
                         KI  +E+K+           +  W+    +  + +   E+EE    
Sbjct: 383 --------------KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR- 427

Query: 294 VPPQVTLWICGLKLQESEEK----EVLQDSPEER 323
              +  +W    K++E EEK    E +++  E+R
Sbjct: 428 -RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 18/135 (13%)

Query: 34  EMNILEINEKLRPQLAENKQQFRNM--------KQKFLVTQMAGFLANQQNKYKYEECK- 84
           E  I E  EK+R Q    ++Q   M        +Q+  + +    +  Q+ K + +E K 
Sbjct: 591 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI 650

Query: 85  ----DLIKSMLREELQFKEEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLREG 136
               + I+    E +Q +EEK+ EQ     +Q E++++ +  +  QE ++ +   +LR+ 
Sbjct: 651 REQEEKIREQ-EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709

Query: 137 RDASHSLNQHLQALL 151
            +      +HL+A +
Sbjct: 710 EEKMQEHQEHLEAAI 724


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 71/336 (21%), Positives = 137/336 (40%), Gaps = 46/336 (13%)

Query: 13   TSSATNVTMVVSAGPWSS-EKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFL 71
            T+S +++T   S G  SS +  + + +       P   E+ ++F  M  K L+   A   
Sbjct: 806  TTSNSSITYKKSYGSTSSSDTCQKSFVSSCTDEEPAEPEDMERFEEMVVKVLIKLQAVQA 865

Query: 72   ANQQNKYKYEECKDLIKSMLREELQFKEEKLA--EQLKQAEELRQYKVLVHSQERELIQL 129
              Q ++ ++ + ++ ++ +L ++   KEE  A   + K+  E  +  +   + + E+ +L
Sbjct: 866  MYQISQEEHSQLQEQMEKLLAKQKDLKEELDACEREFKECMECLEKPMAPQNDKNEIKEL 925

Query: 130  REKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHK-------- 181
            + KLRE +    +       LL   +    Q Q  +E+L +  R  R  V K        
Sbjct: 926  QTKLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQEELRQ-LREKRPSVVKEARGKNAN 984

Query: 182  ---------------LSPENDTDEDENDKTK-------------ELDKVQESPAPREEQK 213
                             P +DT E + +  K             +LD + +    +EE +
Sbjct: 985  KNMNKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAKEEEKKEEME 1044

Query: 214  AEEKEVPEDSLEECA-ITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQ 272
             E+K+V E++ E+C     +    P ++       +  +EEDK       DSE  +D+  
Sbjct: 1045 EEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQEE--NEEDKEEEEKEEDSEEEEDDAD 1102

Query: 273  DALNILLEN---QNDDEEEEGKAPVPPQVTLWICGL 305
             +L    EN   +  + ++    P PP  +L + GL
Sbjct: 1103 SSLESPEENNPLRLSESKKSSPTPNPPIFSLPLVGL 1138



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 58/305 (19%), Positives = 127/305 (41%), Gaps = 17/305 (5%)

Query: 39  EINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREELQFK 98
           E NE L+ QL + + + R +K        +  + NQ  K     C+     +  + +  +
Sbjct: 384 EQNELLKMQL-QLQTELRQLK-----VMKSTLVENQSEKELL--CRLQKLHLQHQNVTCE 435

Query: 99  EEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDN 158
           +EKL E+ +Q +E  Q         R+ +   ++  E    +H+  Q ++ L    K + 
Sbjct: 436 KEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDEL 495

Query: 159 SQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDK-VQESPAPREEQKAEEK 217
            + +   +QL +   L +  + +L   +   ED+     + D  +      +E+ KA +K
Sbjct: 496 ERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQK 555

Query: 218 EVPEDSLEECAITYSNSHGPSDSNPPHKNI-KITSEEDKVNSILVVDSESSQDEWQDALN 276
           E+ +  +E+C +         +     + + ++T    K  S L++ S+    + +D   
Sbjct: 556 EMGQLQMEQCELLEDQRRMQEEQGQLQEELHRLTLPLPK--SGLLLKSQELLTKLEDLCE 613

Query: 277 ILLENQNDDEEEE-----GKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDH 331
           + L  Q   EE++         +  Q+ +     + +ES  +EVL++  + ++  S   +
Sbjct: 614 LQLLYQGMQEEQKKLIQNQDCVLKEQLEIHEELRRFKESHFQEVLENPDDSKLAKSSKCN 673

Query: 332 DVSQS 336
              QS
Sbjct: 674 RNKQS 678



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 61/281 (21%), Positives = 108/281 (38%), Gaps = 20/281 (7%)

Query: 129 LREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF---REQLAEGCRLARHLVHKLSPE 185
           L+E+L+E R+  H LN+  +AL   +     Q  D    R Q A    L    +   S E
Sbjct: 222 LQEELQELRERYHFLNEEYRALQESNSSLTGQLADLESERTQRATERWLQSQTLSMTSAE 281

Query: 186 NDTDE-DENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPH 244
           + T E D  +   E+  +++     EEQ    K   +   E C       H    S    
Sbjct: 282 SQTSEMDFLEPDPEMQLLRQQLRDAEEQMHGMKNKCQ---ELCCELEELQHHRQVSEEEQ 338

Query: 245 KNIK--ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKA-PVPPQVTLW 301
           + ++  +   +++V       S +  +E +  L  L +  +  ++E+ +   +  Q+   
Sbjct: 339 RRLQRELKCAQNEVLRFQTSHSVTQNEELKSRLCTLQKKYDTSQDEQNELLKMQLQLQTE 398

Query: 302 ICGLKLQES------EEKEVL---QDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKV 352
           +  LK+ +S       EKE+L   Q    +    +C    + +  Q  +        +  
Sbjct: 399 LRQLKVMKSTLVENQSEKELLCRLQKLHLQHQNVTCEKEKLLERQQQLQEELQCHEAELQ 458

Query: 353 CSAQDVAS-EHSNSKGEETPLGFPDTKYCWKDEKDERMSQK 392
                VAS + SN K  ET     + K  ++  KDE   QK
Sbjct: 459 HLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQK 499


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 74/384 (19%), Positives = 157/384 (40%), Gaps = 63/384 (16%)

Query: 28  WSSE----KAEMNILEINEKLRPQ---LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           W  E    + E  + E  EK+R Q   + E +++ R +++K           ++Q K + 
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM----------HEQEKIRE 408

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
           +E K   +  +RE+ + ++E+ A+  +Q E++R+ +  +  QE+++ +  EK+ E     
Sbjct: 409 QEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467

Query: 141 HSLNQHLQALLTPDK---HDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTK 197
               +  Q  +   +   H+  +    +E++ E     R    K+  + +   ++ +K +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527

Query: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257
           E    QE    R+E+K  E+   E+   E    +       +     +  K+  +E+K+ 
Sbjct: 528 E----QEEKMWRQEEKIREQ---EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580

Query: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK-EVL 316
                  E  +  W+    I  + +   E+EE          +W    K++E EEK +  
Sbjct: 581 -------EQEEKVWRQEEKIREQEEKRQEQEE---------KMWKQEEKIREQEEKIQEQ 624

Query: 317 QDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPD 376
           ++   E+        +++Q  +   G      E+K+C  ++   E      EET      
Sbjct: 625 EEKIREQEEKIREQEEMTQEQEEKMGE----QEEKMCEQEEKMQEQ-----EET------ 669

Query: 377 TKYCWKDEKDERMSQKVAFLLDEK 400
               W+ E+  R  +K     +EK
Sbjct: 670 ---MWRQEEKIREQEKKIREQEEK 690



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 58/285 (20%), Positives = 119/285 (41%), Gaps = 21/285 (7%)

Query: 32  KAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECK---DLIK 88
           + E  I E  E  R +   ++Q+ +  KQ+  V +    +  Q+ K + +E K      K
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539

Query: 89  SMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQ 148
              +EE+  +EEK+ EQ K  EE ++ +     QE ++ +  EK+RE  +      + + 
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQE-----QEDKMWRQEEKIREQEEKVWRQEEKI- 593

Query: 149 ALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAP 208
                 +    + Q+  E++ +     R    K+  + +   ++ +K +E    QE    
Sbjct: 594 ------REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE----QEEMTQ 643

Query: 209 REEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQ 268
            +E+K  E+E      EE       +    +     +  KI  +E+K+     +  E  +
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703

Query: 269 DEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313
             W+    +  + +   E+EE       +  +W   ++L++ EEK
Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMR--RQEEKMWEQEVRLRQQEEK 746



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 58/314 (18%), Positives = 125/314 (39%), Gaps = 17/314 (5%)

Query: 93  EELQFKEEKLAEQLKQAE-ELRQYKVLVHSQERELIQLREKLREGR---DASH------S 142
           EEL+ K  KL E+L+  E E  + ++ V   +R+L + +  L + +   +A H      S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276

Query: 143 LNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKV 202
           ++  LQA +  ++  N   Q   E++       +    K+  + +   ++ +K +E    
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE---- 332

Query: 203 QESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKV--NSIL 260
           QE    R+E+   EKE      EE            +     K  K+  +E+ +      
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392

Query: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320
           + + E    E +       + Q +++  E +     +  +W    K++E EEK   Q+  
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452

Query: 321 EERVTTSCSDHD-VSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDTKY 379
             R      + + + +  +  E   +   E+K+   +++  +      +E  +   + K 
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512

Query: 380 CWKDEKDERMSQKV 393
             ++EK     +K+
Sbjct: 513 WRQEEKIREQEEKI 526



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 57/233 (24%), Positives = 94/233 (40%), Gaps = 22/233 (9%)

Query: 14  SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73
           ++ TN     S G  S E  +    +  E LR +L       R +  +    QMA + + 
Sbjct: 91  NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ 150

Query: 74  QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122
              K    E +DLI S L +  +F  E       +A Q K+A    EEL + +  +  + 
Sbjct: 151 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 209

Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173
                 + EL +   KL+E      S    +Q  +   K    + +    ++QL AE   
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269

Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEE 226
           L + L   +S +     +EN+    L++ QE    R+E+K +E E      EE
Sbjct: 270 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 321


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 65/303 (21%), Positives = 134/303 (44%), Gaps = 47/303 (15%)

Query: 29  SSEKAEMNILEINEKLRPQLAENKQQFRNMKQ--------KFLVTQMAGFLANQQNKYKY 80
           ++E+ +    E+ EKLR   +E  +   N+K+        KFL+ Q+      ++   + 
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240

Query: 81  EECKDLIKSMLREELQF--KEEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLR 134
           EE ++  K + ++E +   +EE+L EQ     +Q E++R+ +  +  QE+EL +  ++LR
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300

Query: 135 EGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEND 194
           E +     L +  + +   ++    Q +  REQ  +  R    L  +     + ++   D
Sbjct: 301 EQK----KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356

Query: 195 KTKELDKVQESPAPREEQKAEEKEV--PEDSLEECAITYSNSHGPSDSNPPHKNIKITSE 252
           + + + +  E    +EE+  E++++   E+ ++E                     +I   
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQE-------------------EERIRER 397

Query: 253 EDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQ--VTLWICGLKLQES 310
           E K+      + E +  E ++ +    EN  + EE+E +    P+    LW    K+QE 
Sbjct: 398 EKKMR-----EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQ 451

Query: 311 EEK 313
           EEK
Sbjct: 452 EEK 454



 Score = 36.2 bits (82), Expect = 0.057
 Identities = 59/332 (17%), Positives = 136/332 (40%), Gaps = 53/332 (15%)

Query: 31  EKAEMNILEINEKLRPQ----------LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           ++ E  + E  EK+R Q          L E ++Q R  +QK    +   +  +++ + K 
Sbjct: 313 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 372

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLK----QAEELRQYKVLVHSQERELIQLREK---- 132
           E  ++  K   +EE   +EE++ E+ K    + E +R+ +  +  QE  + +  EK    
Sbjct: 373 ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432

Query: 133 --LREGRD---ASHSLNQHLQALLTPDKHDNSQ----GQDFR-----------EQLAEGC 172
             L E ++       + +  + +   ++    Q    GQ+ +           +Q+ E  
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492

Query: 173 RLARHLVHKLSPENDTDEDENDKTKELD---KVQESPAPREEQKAEEKEVPEDSLEECAI 229
              R    K+  + +   +++++ +E +   + Q+    +EE+  EEK+  E   +    
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK---- 548

Query: 230 TYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEE 289
           T+       +     +  K   EE+++        +  +++ ++    + E +   +E+E
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608

Query: 290 GKAPVPPQVTLWICGLKLQESEEKEVLQDSPE 321
            K        +W    K+ E EE++ +Q+  E
Sbjct: 609 EK--------MWEQEEKMWEQEEEDKMQEQEE 632



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 37/210 (17%), Positives = 93/210 (44%), Gaps = 20/210 (9%)

Query: 30  SEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKS 89
           +++ E    +  EK+R +    +++ +  +++ ++ +    +  Q+ K + +E K   + 
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601

Query: 90  MLREELQFKEEKLAEQ-------------LKQAEELRQYKVLVHSQERELIQLREKLREG 136
              E++Q +EEK+ EQ              +Q E + + +  +  QE ++ +  EK+RE 
Sbjct: 602 ---EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658

Query: 137 RDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKT 196
            +      + +Q      +    + Q   E++ E     R    K+  + +    + +K 
Sbjct: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718

Query: 197 KELDKVQESPAPREEQKAEEKEVPEDSLEE 226
              ++++E    +EE+  ++KE  ++ L E
Sbjct: 719 WGQEEMRE----KEERIRDQKEKMQERLPE 744


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 71/309 (22%), Positives = 136/309 (44%), Gaps = 60/309 (19%)

Query: 30  SEKAE--MNILEINEKLR------PQLAENKQQFRNMKQKFLVTQMAGFLANQQNK-YKY 80
           SEK+E  +N+ E+  KL       PQ+  N  Q    +Q+  + +    +  Q+ K ++ 
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298

Query: 81  EE--------CKDLIKSMLREE--LQFKEEKLAEQ---LKQAEELRQYKVLVHSQERELI 127
           EE         ++  + M R+E  L+ +E++L EQ   L++ +ELR+ +  +  QE ++ 
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358

Query: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187
           +  EK+RE  +    + +  + L   +K    Q Q  R+Q             ++  +++
Sbjct: 359 EQEEKMREQEE---KMWRQEERLWEQEKQMREQEQKMRDQ-----------EERMWEQDE 404

Query: 188 TDEDENDKTKELDKVQES-PAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKN 246
              ++ ++ +E +K+ E     REE+K +E+E      EE                  + 
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE---------------KMQEE 449

Query: 247 IKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQ--VTLWICG 304
            +I   E K+      + E +  E ++ +    EN  + EE+E +    P+    LW   
Sbjct: 450 ERIREREKKMR-----EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-Q 503

Query: 305 LKLQESEEK 313
            K+QE EEK
Sbjct: 504 EKMQEQEEK 512



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 56/303 (18%), Positives = 128/303 (42%), Gaps = 34/303 (11%)

Query: 31  EKAEMNILEINEKLRPQ----------LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           ++ E  + E  EK+R Q          L E ++Q R  +QK    +   +  +++ + K 
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLRE-KLREGRDA 139
           E  ++  K   + E   +E+K+ EQ K+  +  +       QE E I+ RE K+RE  + 
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE-----KMQEEERIREREKKMREEEET 465

Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLV---HKLSPENDTDEDENDKT 196
                + +Q      + +N   Q+ +E   +     +  +    K+  + +   ++ +K 
Sbjct: 466 MREQEEKMQ-----KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520

Query: 197 KELDKV--QESPAPREEQKAEEKE---VPEDSLEECAITYSNSHGPSDSNPPHKNIKITS 251
           ++ +++  QE    R+E+  E+++     E+ + +      +     +     +  K   
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580

Query: 252 EEDKV-NSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQES 310
           +E+K+     + + E    E ++    ++  Q +  +E+ +     +  +W    K+QE 
Sbjct: 581 QEEKMREEERMREREKKMREEEE----MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636

Query: 311 EEK 313
           EEK
Sbjct: 637 EEK 639



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 50/256 (19%), Positives = 97/256 (37%), Gaps = 32/256 (12%)

Query: 28  WSSEKA---EMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECK 84
           W  EK    E  + E  EK+R Q  +   Q   M++K    +   +  +Q+ K + EE  
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW--DQEEKMREEERM 591

Query: 85  DLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLN 144
              +  +REE +   E+  +  +Q E++++ +  +  QE ++ +  EK+ E  +      
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651

Query: 145 QHL--QALLTPDK-----HDNSQGQDFREQLAEGCRLARHLVHKLSP------------- 184
           + +  Q  L   K     H+  Q Q+  ++  E       +  K                
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711

Query: 185 -------ENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGP 237
                  E    E+E    ++ +K+QE     +EQ+ E  E  E   E+    +     P
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771

Query: 238 SDSNPPHKNIKITSEE 253
                  ++ K+  +E
Sbjct: 772 EQKEKLWEHEKMQEQE 787



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 43/206 (20%), Positives = 92/206 (44%), Gaps = 24/206 (11%)

Query: 34  EMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLRE 93
           E  I E  +K+R    E ++  R  ++K +  Q       ++ +++ +   +  + +  +
Sbjct: 449 EERIREREKKMR----EEEETMREQEEK-MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503

Query: 94  E-LQFKEEKLAEQ---LKQAEEL--------RQYKVLVHSQERELIQLREKLREGRDASH 141
           E +Q +EEK+ EQ   ++  EE+        RQ K+    QE ++ +  EK+R+      
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM--REQEDQMWEQEEKMRDQEQKMW 561

Query: 142 SLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD- 200
              + ++      +    +  D  E++ E  R+ R    K+  E +   ++ +K +E + 
Sbjct: 562 DQEERMEK---KTQEQEKKTWDQEEKMREEERM-REREKKMREEEEMMREQEEKMQEQEE 617

Query: 201 KVQESPAPREEQKAEEKEVPEDSLEE 226
           K+QE      EQ+ + +E  E   E+
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQ 643



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 40/198 (20%), Positives = 89/198 (44%), Gaps = 25/198 (12%)

Query: 31  EKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSM 90
           ++ E  + E  EK+  Q  +  +Q R  +QK  + +       +Q K + +E K   +  
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM--QEQEKMQEQEEKIWEQEK 691

Query: 91  LREELQFKEEKL--AEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQ 148
           + ++ Q +E+K    E++++ E +R+ +  +  +E  + +  EK++E  +      + + 
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751

Query: 149 ALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAP 208
                ++ +    Q+  E++ E  RL         PE      E++K +E +K+ E    
Sbjct: 752 -----EQEEKMWEQE--EKMWEQQRL---------PEQKEKLWEHEKMQEQEKIWE---- 791

Query: 209 REEQKAEEKEVPEDSLEE 226
            +E+K  ++E      EE
Sbjct: 792 -QEEKMRDQEEKMRGQEE 808


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 63/315 (20%), Positives = 131/315 (41%), Gaps = 40/315 (12%)

Query: 28  WSSE----KAEMNILEINEKLR---PQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80
           W  E    + E  + E  EK+R     + E +++ R +++K           ++Q K + 
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM----------HEQEKIRE 394

Query: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLRE-GRDA 139
           +E K   +  +RE+ + ++E+ A+  +Q E++R+ +  +  QE+++ +  EK+ E  +  
Sbjct: 395 QEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453

Query: 140 SHSLNQHLQALLTPDKHDNSQGQDFR--EQLAEGCRLARHLVHKLSPENDTDEDENDKTK 197
                Q  + +   ++    Q + +R  E++ E  ++ R    K+  + +   D+ +K +
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI-RKQEEKVWRQEEKMHDQEEKIR 512

Query: 198 ELDKV---QESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPP------HKNIK 248
           E ++    QE     +E+K  E+E      EE         G  +           +  K
Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572

Query: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308
           I  +E+K+        E  +  W+    I  + +   E+EE          +W    K+ 
Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE---------KMWEQEEKMC 623

Query: 309 ESEEKEVLQDSPEER 323
           E EEK   Q+    R
Sbjct: 624 EQEEKMQEQEEKMRR 638



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/190 (21%), Positives = 89/190 (46%), Gaps = 14/190 (7%)

Query: 42  EKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREE--LQFKE 99
           E++  Q  +  +Q +  KQ+  V +    + +Q+ K + +E K     M R+E  ++ +E
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK-----MWRQEEKIREQE 529

Query: 100 EKLAEQ---LKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQALLTPDKH 156
           EK+ EQ   +++ EE+ Q +     ++ E +Q +EK+R   +      + ++      + 
Sbjct: 530 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589

Query: 157 DNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEE 216
              +  +  E++ E   + +    K+  + +   ++ +K +E    QE    R+E+K  E
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMWE 645

Query: 217 KEVPEDSLEE 226
           +EV     EE
Sbjct: 646 QEVRLRQQEE 655



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 39/193 (20%), Positives = 86/193 (44%), Gaps = 29/193 (15%)

Query: 32  KAEMNILEINEKLRPQLAENKQQFRNM-KQKFLVTQMAGFLANQQNKYKYEECKDLIKSM 90
           K E  +    EK+  Q  + ++Q   M +Q+  + +    +  Q+ K + +E        
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE-------- 543

Query: 91  LREELQFKEEKLAEQ---LKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHL 147
             E +Q +EEK+ EQ   +++ E++R+ +  +  QE ++ + +EK+RE  +    + +  
Sbjct: 544 --EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE---KIWEQE 598

Query: 148 QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKV--QES 205
           + +   ++    Q +   EQ  + C            E    E E    ++ +K+  QE 
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMC----------EQEEKMQEQEEKMRRQEEKMWEQEV 648

Query: 206 PAPREEQKAEEKE 218
              ++E+K +E +
Sbjct: 649 RLRQQEEKMQEHQ 661



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 74/334 (22%), Positives = 129/334 (38%), Gaps = 49/334 (14%)

Query: 14  SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73
           ++ TN     S G  S E  +    +  E LR +L       R +  +    QMA + + 
Sbjct: 91  NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ 150

Query: 74  QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122
              K    E +DLI S L +  +F  E       +A Q K+A    EEL + +  +  + 
Sbjct: 151 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 209

Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173
                 + EL +   KL+E      S    +Q  +   K    + +    ++QL AE   
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269

Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSN 233
           L + L   +S +     +EN+    L++ QE    R+E+K +E E      EE       
Sbjct: 270 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE------- 321

Query: 234 SHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAP 293
                         KI  +E+K+           +  W+    +  + +   E+EE    
Sbjct: 322 --------------KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367

Query: 294 VPPQVTLWICGLKLQESEEK----EVLQDSPEER 323
           +  +  +W    K++E EEK    E +++  E+R
Sbjct: 368 L--EEMMWEKEEKIRELEEKMHEQEKIREQEEKR 399



 Score = 35.4 bits (80), Expect = 0.098
 Identities = 27/121 (22%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 38  LEINEKLRPQ---LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSMLREE 94
           ++  EK+R Q   + E +++ R  K+K  + +    +  Q+ K + +E          E 
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEK--IREQEEKIWEQEEKIREQE----------EM 607

Query: 95  LQFKEEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQAL 150
           +Q +EEK+ EQ     +Q E++++ +  +  QE ++ +   +LR+  +      +HL+A 
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667

Query: 151 L 151
           +
Sbjct: 668 I 668


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 61/258 (23%), Positives = 118/258 (45%), Gaps = 34/258 (13%)

Query: 81   EECKDLIKSMLREELQFKEEKLAEQLKQA----EELRQYKVLVHSQERELIQLREKLREG 136
            E  +D +K+   ++L  KE KL E++ Q     ++++    L   +E    Q  EKL+E 
Sbjct: 1166 EHLQDSVKNT--KDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEE 1223

Query: 137  RDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKT 196
              AS +  Q+L+A L   + D +   D +E+L +  +  + +  ++S   D D+    K 
Sbjct: 1224 LSASSARTQNLKADLQRKEEDYA---DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI 1280

Query: 197  KELDKVQESPAPREEQKAE-----EKEVPEDSLEECAITYSNSHGPSDSNPPHK---NIK 248
             EL+K +   +   + K       ++++    +EE    Y  +    D N   K   +++
Sbjct: 1281 NELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERA--CKDLNVKEKIIEDMR 1338

Query: 249  ITSEED---KVNSILVVDSESSQ--------DEWQDALNIL--LENQNDDEEEEGKAPVP 295
            +T EE    +V    V++++  +        ++W++  N L    NQ  ++E E    V 
Sbjct: 1339 MTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1398

Query: 296  PQVTLWICGLKLQESEEK 313
             ++T      +LQESE+K
Sbjct: 1399 GKLT--NLQDELQESEQK 1414



 Score = 33.9 bits (76), Expect = 0.28
 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 15/148 (10%)

Query: 4   RFFSPVPGST-----SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNM 58
           + F PV  S      S++ +  + V     S E +  +++E +E L  +L EN ++ +N+
Sbjct: 491 KLFGPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLME-DEDLVEEL-ENAEETQNV 548

Query: 59  KQKFLVTQMAGFLANQQNKYKYEECK---DLIKSMLREELQFKEEKLAEQLKQAEELRQY 115
           + K L   +   L   +    +EE +   DLI+ + ++ +  K+EKL  + K  EE+ Q 
Sbjct: 549 ETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQE 608

Query: 116 KVLVHSQ-----ERELIQLREKLREGRD 138
                +Q     +  L+Q RE L E  +
Sbjct: 609 FTQYWAQREADFKETLLQEREILEENAE 636



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 41/221 (18%)

Query: 80   YEECKDLIKSMLR-----EELQFKEEKLAEQLK-QAEELRQYKVLVHSQERELIQLREKL 133
            +EECK+++K+  +     EEL+ + EKL  ++K   +E  + K   H  + +L++ +E L
Sbjct: 1021 WEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETL 1080

Query: 134  -----REGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDT 188
                  E ++ + +L+  +Q ++        +G+    +L +G    +  + +L      
Sbjct: 1081 IQQLKEELQEKNVTLDVQIQHVV--------EGKRALSELTQGVTCYKAKIKEL------ 1126

Query: 189  DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248
                 +   E  KV+ S + + EQ   EKE     LE     +      S  N    N+K
Sbjct: 1127 -----ETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1181

Query: 249  ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEE 289
                ++++  +         +  QD  ++L   Q  +EEEE
Sbjct: 1182 ELKLKEEITQL--------TNNLQDMKHLL---QLKEEEEE 1211



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 50/241 (20%), Positives = 101/241 (41%), Gaps = 54/241 (22%)

Query: 38   LEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIKSM--LREEL 95
            LE  E+L  +L + K++  +++ K           NQ++  ++E   D++  +  L++EL
Sbjct: 1359 LEEVERLATELEKWKEKCNDLETK----------NNQRSNKEHENNTDVLGKLTNLQDEL 1408

Query: 96   QFKEEK--------------LAEQLKQAEELRQYKVLVHSQERE------------LIQL 129
            Q  E+K              L  Q K+AE +R  ++  ++++RE              QL
Sbjct: 1409 QESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQL 1468

Query: 130  RE------KLREGRD-ASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKL 182
             E      K RE RD    +L   L+AL++ +   +++ +  +  ++E  ++   ++  +
Sbjct: 1469 TEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQIM-DI 1527

Query: 183  SPENDTDEDENDKTKELDKVQESPAPREEQKAEEK-EVPEDSLEECAITYSNSHGPSDSN 241
             P+  +  D        DK+Q  P     + +  K E     L+ C ++  N        
Sbjct: 1528 KPKRISSADP-------DKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTRFPK 1580

Query: 242  P 242
            P
Sbjct: 1581 P 1581



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 54/271 (19%), Positives = 111/271 (40%), Gaps = 18/271 (6%)

Query: 76  NKYKYEECK---DLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQE-RELIQLRE 131
           N+ K E  K   +LIK+  +EEL+ +E + ++ L Q  E    K++  +Q  +ELI + +
Sbjct: 678 NQIKAELAKTKGELIKT--KEELKKRENE-SDSLIQELETSNKKIITQNQRIKELINIID 734

Query: 132 KLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLA--EGCRLARHLVHKLSPE---- 185
           +  +  +   +L  H++     +   ++       +L   E   + +    K+  E    
Sbjct: 735 QKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRV 794

Query: 186 NDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPE-DSLEECAITYSNSHGPSDSNPPH 244
           N+ +  +++   +   +  S A  E+QK  E+  P    +E+  +   N+ G        
Sbjct: 795 NENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTI 854

Query: 245 KNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICG 304
           +N     +E+K      +     +    +  N+ L  +    +      +     L +  
Sbjct: 855 ENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAI---AELHVQK 911

Query: 305 LKLQESEEKEVLQDSPEERVTTSCSDHDVSQ 335
            K QE EEK +++ S E    T    ++VSQ
Sbjct: 912 SKNQEQEEK-IMKLSNEIETATRSITNNVSQ 941


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 50/262 (19%), Positives = 117/262 (44%), Gaps = 41/262 (15%)

Query: 32  KAEMNILEINEKLRPQ---LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIK 88
           + E  + E  EK+R Q   + E +++ R +++K           ++Q K + +E K   +
Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM----------HEQEKIREQEEKRQEE 369

Query: 89  SMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQ 148
             +RE+ + ++E+ A+  +Q E++R+ +  +  QE  + +  EK+ E  +      + +Q
Sbjct: 370 EKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428

Query: 149 ALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD-KVQESPA 207
                ++ +  + Q+  E++ E  +  R    K+  + +  +++ +K  E + K+ E  A
Sbjct: 429 -----EQEEKMRRQE--EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481

Query: 208 PREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESS 267
             +EQ+ E+    E+ + E                  +  KI  +E+K+     +  E  
Sbjct: 482 KMQEQE-EKMRRQEEKIRE------------------QEKKIREQEEKIREQEEMMQEQE 522

Query: 268 QDEWQDALNILLENQNDDEEEE 289
           +  W+    +  + +   E+EE
Sbjct: 523 EKMWEQEEKMCEQEEKMQEQEE 544



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 83/414 (20%), Positives = 162/414 (39%), Gaps = 36/414 (8%)

Query: 14  SSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLAN 73
           ++ TN     S G  S E  +    +  E LR +L    Q  R +  +    QMA + + 
Sbjct: 79  NNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQ 138

Query: 74  QQNKYKYEECKDLIKSMLREELQFKEE------KLAEQLKQA----EELRQYKVLVHSQ- 122
              K    E +DLI S L +  +F  E       +A Q K+A    EEL + +  +  + 
Sbjct: 139 HAVKQLEGEARDLI-SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 197

Query: 123 ------ERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDF--REQL-AEGCR 173
                 + EL +   KL+E      S    +Q  +   K    + +    ++QL AE   
Sbjct: 198 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 257

Query: 174 LARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSN 233
           L + L   +S +     +EN+    L++ QE    R+E+K +E+E      EE       
Sbjct: 258 LGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316

Query: 234 SHGPSDSNPPHKNIKITSEEDKV--NSILVVDSESSQDEWQDALNILLENQNDDEEEEGK 291
                +     K  K+  +E+ +      + + E    E +       + Q +++  E +
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376

Query: 292 APVPPQVTLWICGLKLQESEEK-----EVLQD------SPEERVTTSCSDHDVSQSYQPC 340
                +  +W    K++E EEK     E++Q+        EE++     +    +     
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436

Query: 341 EGTFLALVEQKVCSAQD-VASEHSNSKGEETPLGFPDTKYCWKDEKDERMSQKV 393
           +   +   E+K+   ++ +  +    + +E  +G  + K C ++ K +   +K+
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 46/225 (20%), Positives = 98/225 (43%), Gaps = 34/225 (15%)

Query: 34  EMNILEINEKLRPQ-----LAENKQQFRNMKQKFLVTQMAGFLANQQNKYKYEECKDLIK 88
           E  I E+ EK+  Q       E +Q+   ++++    +    +  Q+ K + +E K   +
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402

Query: 89  SMLREELQFK----EEKLAEQ----LKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140
             + +E + K    EEK+ EQ     +Q E++R+ +  +  QE+++ +  EK+RE  +  
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462

Query: 141 HSLNQHL---------QALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDED 191
               + +         Q     ++ +  + Q+  E++ E  +  R    K+  + +  ++
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE--EKIREQEKKIREQEEKIREQEEMMQE 520

Query: 192 ENDKTKELD----------KVQESPAPREEQKAEEKEVPEDSLEE 226
           + +K  E +          + QE    R+E+K  E+EV     EE
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEE 565


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.125    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,737,155
Number of Sequences: 37866
Number of extensions: 899468
Number of successful extensions: 8357
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 760
Number of HSP's that attempted gapping in prelim test: 5375
Number of HSP's gapped (non-prelim): 2503
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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