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Search of human proteins with 114155146
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 466 e-132
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 438 e-123
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 422 e-118
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 394 e-110
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 365 e-101
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 358 2e-99
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 331 3e-91
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 317 5e-87
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 315 3e-86
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 313 7e-86
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 310 6e-85
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 310 7e-85
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 310 1e-84
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 306 1e-83
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 303 9e-83
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 302 2e-82
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 266 9e-72
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 82 6e-16
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 76 2e-14
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 76 2e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 73 3e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 73 3e-13
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 73 3e-13
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 72 4e-13
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 70 2e-12
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 70 2e-12
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 70 2e-12
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 70 2e-12
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 70 2e-12
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 70 2e-12
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 466 bits (1199), Expect = e-132
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
Query: 241 TLHDLCD 247
TLHDLCD
Sbjct: 241 TLHDLCD 247
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 438 bits (1127), Expect = e-123
Identities = 232/247 (93%), Positives = 239/247 (96%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
EADRKYEEVARKLVIIEGDLERTEERAELAES+C E++E+++ + NLK L A EKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
Query: 241 TLHDLCD 247
TLHDLCD
Sbjct: 241 TLHDLCD 247
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 422 bits (1085), Expect = e-118
Identities = 228/245 (93%), Positives = 231/245 (94%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE++L E + L
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 241 TLHDL 245
TL DL
Sbjct: 241 TLLDL 245
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 394 bits (1013), Expect = e-110
Identities = 213/245 (86%), Positives = 223/245 (91%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE
Sbjct: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
EADRKYEEVARKLVIIEGDLERTEERAELAES+C E++E+++ + NLK L A EKYSQ
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE++L E + L
Sbjct: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
Query: 241 TLHDL 245
TL DL
Sbjct: 241 TLLDL 245
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 365 bits (936), Expect = e-101
Identities = 189/244 (77%), Positives = 220/244 (90%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
MAG +++EAV+RKI+ LQ+QAD AEERA LQRE++ ER+ RE AEA+VASLNRRIQLVE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+ADRKYEEVARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQ
Sbjct: 121 DADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQ 180
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
KED+YEEEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE++LY QLE+NR L+NELKL
Sbjct: 181 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKL 240
Query: 241 TLHD 244
L++
Sbjct: 241 ALNE 244
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 358 bits (919), Expect = 2e-99
Identities = 185/245 (75%), Positives = 218/245 (88%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE 60
MAG+ ++EAVKRKIQ LQQQAD+AE+RA+ LQRE++GER RE+AE +VA+LNRRIQLVE
Sbjct: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAE
Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
EADRKYEEVARKLVI+EG+LER EERAE++E +C +++E+++ + NLK L AA EKYS+
Sbjct: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
KEDKYEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLEE+L E N L L
Sbjct: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Query: 241 TLHDL 245
TL++L
Sbjct: 241 TLNEL 245
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/161 (21%), Positives = 79/161 (49%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
+R ++V++ +A EE+ E + +++ + E+A+ + + R++ ++E EL+RA+ER
Sbjct: 88 ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 147
Query: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
+ K + E+ +K +E + K EK + E ++K +EA+ + E
Sbjct: 148 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 207
Query: 131 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCL 171
R + +E ++ EE+ A+ + + + L C+
Sbjct: 208 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 248
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 331 bits (849), Expect = 3e-91
Identities = 176/239 (73%), Positives = 202/239 (84%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ A+++K++ + + D E + Q ++E + AEAEVASLNRRIQLVEEELDRA
Sbjct: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY
Sbjct: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
EEVARKLVIIEGDLERTEERAELAES+C E++E+++ + NLK L A EKYSQKEDKYE
Sbjct: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE+ LY+Q + + +S EL L+D+
Sbjct: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 317 bits (813), Expect = 5e-87
Identities = 165/237 (69%), Positives = 200/237 (84%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
Query: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
VARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YEEE
Sbjct: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
Query: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+ LY+Q + + +S EL L+D+
Sbjct: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 41.6 bits (96), Expect = 6e-04
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESRC 154
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
Query: 155 REMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
++ E++ L ++ A +++ EEE+ ++L A + E AE++ + E
Sbjct: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
+ + +E R E+ + +LK H
Sbjct: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 315 bits (806), Expect = 3e-86
Identities = 166/238 (69%), Positives = 199/238 (83%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
+A+++K++ + + + E + Q ++E + AEA+VASLNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
ERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEE 187
EVARKLVI+EG+LER+EERAE+AESR R+++E++R MDQ LK L A+EE+YS KEDKYEE
Sbjct: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
Query: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
EIK+L +KLKEAETRAEFAERSVAKLEKTIDDLEE L S E N + L TL +L
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
Score = 64.3 bits (155), Expect = 9e-11
Identities = 53/241 (21%), Positives = 109/241 (45%), Gaps = 56/241 (23%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A+K+K+Q+L+ ++A +RAE QAEA+ R + +EEE
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAE--------------QAEADKKQAEDRCKQLEEEQQAL 46
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Q++L ++E+ ++ E++ +L++A+ A +A+
Sbjct: 47 QKKLKGTEDEVEKYSESVKEAQE---------------------KLEQAEKKATDAEADV 85
Query: 127 EEVARKLVIIEGDLERTEERAELA---------------------ESRCREMDEQIRLMD 165
+ R++ ++E +L+R +ER A E+R + +E++ L +
Sbjct: 86 ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQE 145
Query: 166 QNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLY 225
LK E +K ++ ++ IL +L+ +E RAE AE +LE+ + +++ L
Sbjct: 146 MQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALK 205
Query: 226 S 226
S
Sbjct: 206 S 206
Score = 53.5 bits (127), Expect = 2e-07
Identities = 29/104 (27%), Positives = 58/104 (55%)
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
+ + +K+ +++ D E +RAE AE+ ++ +++ + +++ + L + + +KY
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
E +K +KL++AE +A AE VA L + I +EE L ER
Sbjct: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQER 105
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 313 bits (803), Expect = 7e-86
Identities = 159/238 (66%), Positives = 201/238 (84%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
+A+++K++ + + + E + Q ++E + AEA+VASLNRRIQLVEEELDRAQ
Sbjct: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
ERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYE
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
Query: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEE 187
EVARKLVI+EG+LER+EERAE+AES+C +++E+++++ NLK L A +KYS KEDKYEE
Sbjct: 164 EVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEE 223
Query: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
EIK+L +KLKEAETRAEFAERSVAKLEKTIDDLE+ +Y+Q + + +S EL L+D+
Sbjct: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDI 281
Score = 34.3 bits (77), Expect = 0.10
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 5 TTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELD 64
T + + +I++L+++ +AE RAE +R V + + E EV + + + + EELD
Sbjct: 216 TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELD 275
Query: 65 RA 66
A
Sbjct: 276 NA 277
Score = 29.3 bits (64), Expect = 3.3
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREV--------EGERRAREQAEAEVASLNRRIQL 58
++ V ++ L+ QAD + ++ + E+ E E RA E AE VA L + I
Sbjct: 197 LKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRA-EFAERSVAKLEKTIDD 255
Query: 59 VEEELDRAQERLATALQKLEEA 80
+E+E+ + + ++L+ A
Sbjct: 256 LEDEVYAQKMKYKAISEELDNA 277
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 310 bits (795), Expect = 6e-85
Identities = 164/237 (69%), Positives = 196/237 (82%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
Query: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
VARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YEEE
Sbjct: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
Query: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
Score = 41.6 bits (96), Expect = 6e-04
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESRC 154
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
Query: 155 REMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
++ E++ L ++ A +++ EEE+ ++L A + E AE++ + E
Sbjct: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
+ + +E R E+ + +LK H
Sbjct: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 310 bits (794), Expect = 7e-85
Identities = 161/237 (67%), Positives = 196/237 (82%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
Query: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
VARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YEEE
Sbjct: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
Query: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+ LY+Q + + +S EL L+D+
Sbjct: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 29.6 bits (65), Expect = 2.5
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREV--------EGERRAREQAEAEVASLNRRIQL 58
++ V ++ L+ QA+ ++ +R + E+ E E RA E AE V L + I
Sbjct: 197 LKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRA-EFAERSVTKLEKSIDD 255
Query: 59 VEEELDRAQERLATALQKLEEA 80
+E+EL + + ++L+ A
Sbjct: 256 LEDELYAQKLKYKAISEELDHA 277
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 310 bits (793), Expect = 1e-84
Identities = 165/239 (69%), Positives = 195/239 (81%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
EEVARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 28/181 (15%)
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
+D ++++ E A A+++E K E+R+ + EE + +E L+ ++ +E
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE---DER 57
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
DR EE+ + E L EE A AE+ ++ +I+L+
Sbjct: 58 DRVLEELHKA----EDSLLAAEEAAAKAEADVASLNRRIQLV------------------ 95
Query: 183 DKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTL 242
EEE+ ++L A + E AE++ + E+ + +E R E+ + +LK
Sbjct: 96 ---EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK 152
Query: 243 H 243
H
Sbjct: 153 H 153
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 306 bits (784), Expect = 1e-83
Identities = 160/236 (67%), Positives = 195/236 (82%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
+++K++ + + D E + Q ++E + AE +VA+LNRRIQLVEEELDRAQER
Sbjct: 46 LQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER 105
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
LATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEV
Sbjct: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 165
Query: 130 ARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEI 189
ARKLVI+EG+LER EERAE++E +C +++E+++ + NLK L AA EKYS+KEDKYEEEI
Sbjct: 166 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 225
Query: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
K+L+DKLKEAETRAEFAER+VAKLEKTIDDLEE+L E N L L TL++L
Sbjct: 226 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/161 (21%), Positives = 79/161 (49%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
+R ++V++ +A EE+ E + +++ + E+A+ + + R++ ++E EL+RA+ER
Sbjct: 124 ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 183
Query: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
+ K + E+ +K +E + K EK + E ++K +EA+ + E
Sbjct: 184 EVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAE 243
Query: 131 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCL 171
R + +E ++ EE+ A+ + + + L C+
Sbjct: 244 RTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
Score = 41.6 bits (96), Expect = 6e-04
Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 28/166 (16%)
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137
E A A+++E K E++ + EE EL +Q K+ K +E D KY E
Sbjct: 16 ENAIDRAEQAEADKKAAEDKCKQVEE--ELTHLQ-KKLKGTEDELD-KYSE--------- 62
Query: 138 GDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLK 197
DL+ +E+ EL E + + + + +++ ++ + EEE+ ++L
Sbjct: 63 -DLKDAQEKLELTEKKASDAEGDVAALNRRIQLV--------------EEELDRAQERLA 107
Query: 198 EAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLH 243
A + E AE++ + E+ + +E R E+ + +LK H
Sbjct: 108 TALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKH 153
Score = 31.6 bits (70), Expect = 0.67
Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 14/105 (13%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE------- 60
E V RK+ +L E ER + E E E+ ++ ++ +E
Sbjct: 163 EEVARKLVIL-------EGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYS 215
Query: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKM 105
E+ D+ +E + KL+EAE A+ +ER + +E EEK+
Sbjct: 216 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 260
Score = 28.1 bits (61), Expect = 7.4
Identities = 14/81 (17%), Positives = 40/81 (49%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++ V ++ L+ ++ E+ ++ + E++ ++AE R + +E+ +D
Sbjct: 197 LKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDL 256
Query: 67 QERLATALQKLEEAEKAADES 87
+E+LA A ++ + D++
Sbjct: 257 EEKLAQAKEENVGLHQTLDQT 277
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 303 bits (776), Expect = 9e-83
Identities = 160/237 (67%), Positives = 192/237 (81%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
Query: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
VARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YEEE
Sbjct: 165 VARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE 224
Query: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 302 bits (774), Expect = 2e-82
Identities = 161/239 (67%), Positives = 191/239 (79%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
EEVARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YE
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 266 bits (681), Expect = 9e-72
Identities = 143/239 (59%), Positives = 186/239 (77%), Gaps = 11/239 (4%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E +L ++++ E+E++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-- 58
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
K E+EKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKY
Sbjct: 59 ---------KYSESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKY 109
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
EEVARKLVI+EG+LER+EERAE+AESR R+++E++R MDQ LK L A+EE+YS KEDKYE
Sbjct: 110 EEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYE 169
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
EEIK+L +KLKEAETRAEFAERSVAKLEKTIDDLEE L S E N + L TL +L
Sbjct: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 228
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 81.6 bits (200), Expect = 6e-16
Identities = 56/241 (23%), Positives = 125/241 (51%), Gaps = 22/241 (9%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREV----EGERRAREQAEAEVASLNRRIQLVEEEL 63
E ++ + + +Q+Q + E+ E+++R+ E E + R Q E + +I+ +EE++
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM-MWEKEEKIRELEEKM 353
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
QE++ +K +E EK ++ +R + E + + EEK+ QE +++E + + +E +
Sbjct: 354 -HEQEKIREQEEKRQEEEKIREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEMMQEQE 410
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLK----CLSAAEEKYS 179
K E K+ E +++ EE+ E + RE +++IR ++ ++ + EEK
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 180 QKEDK----------YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++E K EE+++ +K++E E + E + + E+ + + EE+++ Q E
Sbjct: 471 EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 530
Query: 230 R 230
+
Sbjct: 531 K 531
Score = 77.8 bits (190), Expect = 8e-15
Identities = 51/218 (23%), Positives = 110/218 (50%), Gaps = 12/218 (5%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQA-----EAEVASLNRRIQLVEEELDRAQERLAT 72
Q++ + EE+ + ++ E E+R ++A E ++ +I+ EE + +E++
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
+K+ E E+ E E M+ E + + E+K+ QE +++E + + +E + K E K
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK 475
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
+ E ++ EE+ E + RE +++IR ++ ++ EE ++E+K E+
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR---EQEEMMQEQEEKMWEQ---- 528
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
+K+ E E + + E + + E+ + + E RL Q E+
Sbjct: 529 EEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 74.3 bits (181), Expect = 9e-14
Identities = 62/245 (25%), Positives = 120/245 (48%), Gaps = 29/245 (11%)
Query: 7 IEAVKRKI---------QVLQQQAD----DAEERAERLQREVEGER---RAREQAEAEVA 50
++ +KRK+ Q LQ +AD + + + +LQ +VE R +Q E ++
Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291
Query: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
+IQ EE++ +E++ +K+ E+ E E M+ E + EEK+ E
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
Query: 111 QLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAEL--AESRCREMDEQIRLMDQNL 168
++ E + I E+ +++ EE I +R E+ A++ E + RE +E+IR ++
Sbjct: 352 KMHEQEKIREQEEKRQEEEK-----IREQEKRQEQEAKMWRQEEKIREQEEKIREQEE-- 404
Query: 169 KCLSAAEEKYSQKEDK---YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLY 225
+ EEK ++E+K EEE++ +K++ E + E+ + + E+ I + EE +
Sbjct: 405 -MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 226 SQLER 230
Q E+
Sbjct: 464 EQEEK 468
Score = 70.9 bits (172), Expect = 1e-12
Identities = 52/229 (22%), Positives = 117/229 (51%), Gaps = 8/229 (3%)
Query: 8 EAVKRKIQVLQQQADDAEERAERL-QREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
E ++R+ +++ ++ + E E++ ++E E+ + Q E ++ +R Q E ++ R
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQ 388
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
+E++ +K+ E E+ E E M E + + EE+M+ QE +++ + E ++K
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK-- 184
E K+ E ++ EE+ + E + +++ ++ +Q K + EEK ++E K
Sbjct: 449 REQEEKIREQEEMMQEQEEK--MGEQEGKMCEQEAKMQEQEEK-MRRQEEKIREQEKKIR 505
Query: 185 -YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
EE+I+ + ++E E + E + + E+ + + EE++ Q E+ R
Sbjct: 506 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Score = 63.2 bits (152), Expect = 2e-10
Identities = 51/228 (22%), Positives = 115/228 (50%), Gaps = 20/228 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E + R+ + +Q++ + +E+ E+++ + E RR E + + R+ +++ E+ +
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK----E 343
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
E++ +K+ E EK ++ E+ E ++++EK + QE ++ EE R+ E
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQ---EEEKIREQEKRQEQEAKMWRQ----EEKIREQE 396
Query: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK--- 184
E R+ E ++ EE+ E + E +E+++ ++ ++ EEK ++E K
Sbjct: 397 EKIREQ---EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR---RQEEKIREQEKKIRE 450
Query: 185 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
EE+I+ + ++E E + E + + E + + EE++ Q E+ R
Sbjct: 451 QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Score = 62.8 bits (151), Expect = 3e-10
Identities = 45/193 (23%), Positives = 89/193 (46%), Gaps = 21/193 (10%)
Query: 25 EERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 84
EE+ + ++ + ++ E ++ ++ EEE+ +E++ +K+ E EK
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 85 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 144
E E ++ E + EEKM QE ++ E + +E + K + R E
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK--------------MRRQE 494
Query: 145 ERAELAESRCREMDEQIR----LMDQNLKCLSAAEEKYSQKEDK---YEEEIKILTDKLK 197
E+ E + RE +E+IR +M + + + EEK ++E+K EE+++ +K++
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 198 EAETRAEFAERSV 210
E E R E +
Sbjct: 555 EQEVRLRQQEEKM 567
Score = 60.1 bits (144), Expect = 2e-09
Identities = 39/183 (21%), Positives = 89/183 (48%), Gaps = 13/183 (7%)
Query: 8 EAVKRKIQVLQQQADDAEERAERL---QREVEGERRAREQAEAEVASLNRRIQLVEEELD 64
E ++ + +++Q+Q + E+ E++ + E++ + + E ++ ++I+ EE++
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 124
+E + +K+ E E E E M+ E + + EEK+ QE +++E + E +
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 125 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK 184
+E K+ E + EE+ + E + R +E++R + L+ Q+E+K
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR----------QQEEK 566
Query: 185 YEE 187
+E
Sbjct: 567 MQE 569
Score = 59.7 bits (143), Expect = 2e-09
Identities = 58/248 (23%), Positives = 109/248 (43%), Gaps = 28/248 (11%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ AV + + + ++ + + L E+ E+ + + A L ++QLVE E
Sbjct: 169 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 228
Query: 67 QERLATALQKLEEA-------EKAADESERGMKV----------IENRAL------KDEE 103
Q + +KLE A + A+ G ++ +E L + EE
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 104 KMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRL 163
KM QE +++E + +E + K E K+ E + EE+ E E +E+IR
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 348
Query: 164 MDQNLKCLSAAEEKYSQKEDKYEEEIKIL-TDKLKEAETRAEFAERSVAKLEKTIDDLEE 222
+++ + +EK ++E+K +EE KI +K +E E + E + + E+ I + EE
Sbjct: 349 LEEKMH----EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 223 RLYSQLER 230
+ Q E+
Sbjct: 405 MMQEQEEK 412
Score = 59.3 bits (142), Expect = 3e-09
Identities = 48/190 (25%), Positives = 94/190 (49%), Gaps = 8/190 (4%)
Query: 12 RKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLA 71
R+ + +++Q + E+ E +Q E E + EQ E ++ +Q EE++ R +E++
Sbjct: 387 RQEEKIREQEEKIREQEEMMQ---EQEEKMGEQEE-KMWEQEEEMQEQEEKMRRQEEKIR 442
Query: 72 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 131
+K+ E E+ E E M+ E + + E KM QE +++E + + K E +
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 132 KLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY-EEEIK 190
K I E+ E+ E+ + + +M EQ M + + + EEK ++E+K E+E++
Sbjct: 503 K---IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVR 559
Query: 191 ILTDKLKEAE 200
+ + K E
Sbjct: 560 LRQQEEKMQE 569
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 76.3 bits (186), Expect = 2e-14
Identities = 54/225 (24%), Positives = 115/225 (51%), Gaps = 5/225 (2%)
Query: 12 RKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLA 71
R+ + +++Q + E+ E++ R+ E R E+ + + + R+ + + E+ ++ QE++
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 72 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 131
+K+ E ++ E E M E + + EE M+ QE +L+E + +E + K +E
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 132 KLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKI 191
K I+ E+ +E+ E + + + ++ ++ +Q K E+ + Q+E E+E K+
Sbjct: 470 K---IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 192 --LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLL 234
+K++E E R E + + E + +LEERL ++ LL
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571
Score = 74.3 bits (181), Expect = 9e-14
Identities = 57/245 (23%), Positives = 122/245 (49%), Gaps = 22/245 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEG----ERRAREQAEA------EVASLNRRIQ 57
E + R+ + + +Q + E+ +++ R+ E E + REQ E ++ + +IQ
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 58 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 117
EEE+ R +E++ ++ E+ ++ E+ M+ + + + EE+M QE +++E +
Sbjct: 385 EQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDE----QIRLMDQNLKCLSA 173
+ ++ + K EV K+ E ++ EE+ + E + +E +E Q +L+ Q K
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRL 233
E+ + Q+E +E+E +K++E E + + E + + E + EE++ Q R +
Sbjct: 502 EEKMWRQEEKMWEQE-----EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 234 LSNEL 238
L L
Sbjct: 557 LEERL 561
Score = 70.9 bits (172), Expect = 1e-12
Identities = 56/219 (25%), Positives = 113/219 (51%), Gaps = 16/219 (7%)
Query: 25 EERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 84
+++ E++ R+ E + +EQ E ++ +I+ EE++ R +E++ +K+ E E
Sbjct: 293 QQQEEKMWRQ---EEKIQEQEE-KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 85 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 144
E ++ E + + EEKM QE +++E +E + EE+ R+ I E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWRQEEKIREQEEKRQ 405
Query: 145 ERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY---EEEIKILTDKLKEAET 201
E+ E + RE DE+IR ++ + EEK + E+ EE+++ + +K++E E
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMW---RQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 202 RAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + E + + E+ I + EE+ + Q +LL E K+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQ---EKLLKQEEKI 498
Score = 69.3 bits (168), Expect = 3e-12
Identities = 64/246 (26%), Positives = 117/246 (47%), Gaps = 30/246 (12%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERL----QREVEGERRARE--------QAEAEVASL-N 53
+E+ K +IQ+ + ERA+ L Q +VE +R +E QA+ E L N
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN 289
Query: 54 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
Q EE++ R +E K++E E+ E E ++ E + + EEKM QE +++
Sbjct: 290 LLNQQQEEKMWRQEE-------KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
E + + K E K + EE+ E + RE DE+I+ ++ +
Sbjct: 343 EQEDKMWRQEEKIREQEEK-------IREQEEKMWRQEEKIREQDEKIQEQEEE---MWR 392
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRL 233
EEK ++E+K +E++ K++E + + E + + E+ I +LEE + Q E+ R
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452
Query: 234 LSNELK 239
+ +++
Sbjct: 453 VEEKMQ 458
Score = 66.6 bits (161), Expect = 2e-11
Identities = 50/221 (22%), Positives = 117/221 (52%), Gaps = 10/221 (4%)
Query: 18 QQQADDAEERAERLQRE----VEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATA 73
QQQ + + E++Q + E E + REQ E ++ ++ EE++ ++++
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE-KMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 74 LQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQL-KEAKHIAEEADRKYEEVARK 132
+K+ E E+ E E M E + + +EK++ QE ++ ++ + I E+ +++ E++ R+
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 133 LVIIEGDLERTEERAE---LAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEI 189
+ E+ E+ E E + RE++E ++ ++ L+ + ++ +K + EE+I
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
Query: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
+ +K++E E + + + + K E+ I + EE+++ Q E+
Sbjct: 472 QRQEEKIQEQEEKT-WRQEKLLKQEEKIWEQEEKMWRQEEK 511
Score = 66.2 bits (160), Expect = 2e-11
Identities = 50/211 (23%), Positives = 110/211 (52%), Gaps = 18/211 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E + R+ + +++Q + +E+ E + R+ E R E+ + ++ ++++ +E++ +
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQE--IQLKEAKHIAEEADRK 125
E + +K+ E E+ + E ++ +E + ++EEKM+ QE IQ +E K I E+ ++
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK-IQEQEEKT 485
Query: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
+ + KL+ E + EE+ E + E +E+ + EEK ++E+K
Sbjct: 486 WRQ--EKLLKQEEKIWEQEEKMWRQEEKMWEQEEK----------MQEQEEKMQRQEEKM 533
Query: 186 -EEEIKI--LTDKLKEAETRAEFAERSVAKL 213
E+E+++ +K++E E R + E + KL
Sbjct: 534 REQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
Score = 62.4 bits (150), Expect = 4e-10
Identities = 56/235 (23%), Positives = 115/235 (48%), Gaps = 14/235 (5%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEG----ERRAREQAEAEVASLNRRIQLVEEEL 63
E ++ + + + +Q E+ E++ R+ E E + REQ E ++ +I+ EE++
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ-EDKMWRQEEKIREQEEKI 362
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
+E++ +K+ E ++ E E M E + + EEK QE ++ K + E+ D
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQ-D 419
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIR----LMDQNLKCLSAAEEKYS 179
K E ++ E + EE + E + RE++E+++ M + + + EEK
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 180 QKEDKYEEEIKIL--TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
++E+K + K+L +K+ E E + E + + E+ + + EE++ Q E+ R
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Score = 59.3 bits (142), Expect = 3e-09
Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 11/185 (5%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
+ KI+ L++ D EE+ ++ +++ E ++ E ++ +IQ EE+ R QE+L
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKL 491
Query: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
+K+ E E+ E M E + + EEKM+ QE +++E + + + K +E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 131 RKLVIIEGDLERTEERAELAESRCREMDE----------QIRLMDQNLKCLSAAEEKYSQ 180
+L +E L + ++AEL RE Q+ L Q + L ++ Y
Sbjct: 552 VRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRG 611
Query: 181 KEDKY 185
+Y
Sbjct: 612 HLQQY 616
Score = 48.9 bits (115), Expect = 4e-06
Identities = 51/222 (22%), Positives = 100/222 (45%), Gaps = 31/222 (13%)
Query: 34 EVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 93
EV ++R E + +++ +ER A +L+ + E+ ++
Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAEL 223
Query: 94 IENRALKDEEKMELQEIQLKEAKHIAE-------------EADR---KYEEVARKL--VI 135
E L + EK E+Q + +K+ K E EADR + + V+ KL +
Sbjct: 224 QEKLRLVESEKSEIQ-LNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 136 IEGDL-----ERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIK 190
E +L ++ EE+ E + +E +E ++ +Q LK E+ + Q+E +E+E
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEE--KMCEQELKIREQEEKMWRQEEKMHEQE-- 338
Query: 191 ILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+K++E E + E + + E+ I + EE+++ Q E+ R
Sbjct: 339 ---EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 76.3 bits (186), Expect = 2e-14
Identities = 54/225 (24%), Positives = 115/225 (51%), Gaps = 5/225 (2%)
Query: 12 RKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLA 71
R+ + +++Q + E+ E++ R+ E R E+ + + + R+ + + E+ ++ QE++
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 72 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 131
+K+ E ++ E E M E + + EE M+ QE +L+E + +E + K +E
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 132 KLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKI 191
K I+ E+ +E+ E + + + ++ ++ +Q K E+ + Q+E E+E K+
Sbjct: 470 K---IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 192 --LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLL 234
+K++E E R E + + E + +LEERL ++ LL
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571
Score = 74.3 bits (181), Expect = 9e-14
Identities = 57/245 (23%), Positives = 122/245 (49%), Gaps = 22/245 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEG----ERRAREQAEA------EVASLNRRIQ 57
E + R+ + + +Q + E+ +++ R+ E E + REQ E ++ + +IQ
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 58 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 117
EEE+ R +E++ ++ E+ ++ E+ M+ + + + EE+M QE +++E +
Sbjct: 385 EQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDE----QIRLMDQNLKCLSA 173
+ ++ + K EV K+ E ++ EE+ + E + +E +E Q +L+ Q K
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRL 233
E+ + Q+E +E+E +K++E E + + E + + E + EE++ Q R +
Sbjct: 502 EEKMWRQEEKMWEQE-----EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 234 LSNEL 238
L L
Sbjct: 557 LEERL 561
Score = 70.9 bits (172), Expect = 1e-12
Identities = 56/219 (25%), Positives = 113/219 (51%), Gaps = 16/219 (7%)
Query: 25 EERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 84
+++ E++ R+ E + +EQ E ++ +I+ EE++ R +E++ +K+ E E
Sbjct: 293 QQQEEKMWRQ---EEKIQEQEE-KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 85 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 144
E ++ E + + EEKM QE +++E +E + EE+ R+ I E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWRQEEKIREQEEKRQ 405
Query: 145 ERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY---EEEIKILTDKLKEAET 201
E+ E + RE DE+IR ++ + EEK + E+ EE+++ + +K++E E
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMW---RQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 202 RAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + E + + E+ I + EE+ + Q +LL E K+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQ---EKLLKQEEKI 498
Score = 69.3 bits (168), Expect = 3e-12
Identities = 64/246 (26%), Positives = 117/246 (47%), Gaps = 30/246 (12%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERL----QREVEGERRARE--------QAEAEVASL-N 53
+E+ K +IQ+ + ERA+ L Q +VE +R +E QA+ E L N
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN 289
Query: 54 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
Q EE++ R +E K++E E+ E E ++ E + + EEKM QE +++
Sbjct: 290 LLNQQQEEKMWRQEE-------KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
E + + K E K + EE+ E + RE DE+I+ ++ +
Sbjct: 343 EQEDKMWRQEEKIREQEEK-------IREQEEKMWRQEEKIREQDEKIQEQEEE---MWR 392
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRL 233
EEK ++E+K +E++ K++E + + E + + E+ I +LEE + Q E+ R
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452
Query: 234 LSNELK 239
+ +++
Sbjct: 453 VEEKMQ 458
Score = 66.6 bits (161), Expect = 2e-11
Identities = 50/221 (22%), Positives = 117/221 (52%), Gaps = 10/221 (4%)
Query: 18 QQQADDAEERAERLQRE----VEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATA 73
QQQ + + E++Q + E E + REQ E ++ ++ EE++ ++++
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE-KMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 74 LQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQL-KEAKHIAEEADRKYEEVARK 132
+K+ E E+ E E M E + + +EK++ QE ++ ++ + I E+ +++ E++ R+
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 133 LVIIEGDLERTEERAE---LAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEI 189
+ E+ E+ E E + RE++E ++ ++ L+ + ++ +K + EE+I
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
Query: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
+ +K++E E + + + + K E+ I + EE+++ Q E+
Sbjct: 472 QRQEEKIQEQEEKT-WRQEKLLKQEEKIWEQEEKMWRQEEK 511
Score = 66.2 bits (160), Expect = 2e-11
Identities = 50/211 (23%), Positives = 110/211 (52%), Gaps = 18/211 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E + R+ + +++Q + +E+ E + R+ E R E+ + ++ ++++ +E++ +
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQE--IQLKEAKHIAEEADRK 125
E + +K+ E E+ + E ++ +E + ++EEKM+ QE IQ +E K I E+ ++
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK-IQEQEEKT 485
Query: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
+ + KL+ E + EE+ E + E +E+ + EEK ++E+K
Sbjct: 486 WRQ--EKLLKQEEKIWEQEEKMWRQEEKMWEQEEK----------MQEQEEKMQRQEEKM 533
Query: 186 -EEEIKI--LTDKLKEAETRAEFAERSVAKL 213
E+E+++ +K++E E R + E + KL
Sbjct: 534 REQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
Score = 62.4 bits (150), Expect = 4e-10
Identities = 56/235 (23%), Positives = 115/235 (48%), Gaps = 14/235 (5%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEG----ERRAREQAEAEVASLNRRIQLVEEEL 63
E ++ + + + +Q E+ E++ R+ E E + REQ E ++ +I+ EE++
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ-EDKMWRQEEKIREQEEKI 362
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
+E++ +K+ E ++ E E M E + + EEK QE ++ K + E+ D
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQ-D 419
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIR----LMDQNLKCLSAAEEKYS 179
K E ++ E + EE + E + RE++E+++ M + + + EEK
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 180 QKEDKYEEEIKIL--TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
++E+K + K+L +K+ E E + E + + E+ + + EE++ Q E+ R
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Score = 59.3 bits (142), Expect = 3e-09
Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 11/185 (5%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
+ KI+ L++ D EE+ ++ +++ E ++ E ++ +IQ EE+ R QE+L
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKL 491
Query: 71 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 130
+K+ E E+ E M E + + EEKM+ QE +++E + + + K +E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 131 RKLVIIEGDLERTEERAELAESRCREMDE----------QIRLMDQNLKCLSAAEEKYSQ 180
+L +E L + ++AEL RE Q+ L Q + L ++ Y
Sbjct: 552 VRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRG 611
Query: 181 KEDKY 185
+Y
Sbjct: 612 HLQQY 616
Score = 48.9 bits (115), Expect = 4e-06
Identities = 51/222 (22%), Positives = 100/222 (45%), Gaps = 31/222 (13%)
Query: 34 EVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 93
EV ++R E + +++ +ER A +L+ + E+ ++
Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAEL 223
Query: 94 IENRALKDEEKMELQEIQLKEAKHIAE-------------EADR---KYEEVARKL--VI 135
E L + EK E+Q + +K+ K E EADR + + V+ KL +
Sbjct: 224 QEKLRLVESEKSEIQ-LNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQV 282
Query: 136 IEGDL-----ERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIK 190
E +L ++ EE+ E + +E +E ++ +Q LK E+ + Q+E +E+E
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEE--KMCEQELKIREQEEKMWRQEEKMHEQE-- 338
Query: 191 ILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+K++E E + E + + E+ I + EE+++ Q E+ R
Sbjct: 339 ---EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 72.8 bits (177), Expect = 3e-13
Identities = 51/223 (22%), Positives = 113/223 (50%), Gaps = 7/223 (3%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E + R+ + +++Q + E + ++E E R++ E ++ +I+ EE++ R +
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
E++ +K +E E+ + E ++ E + + EEK+ QE +++E + + +E + K
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEE 187
E K+ E ++ EE E + RE +++IR ++ ++ EE ++E+K E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR---EQEEMMQEQEEKMWE 707
Query: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
+ +K+ E E + + E + + E+ + + E RL Q E+
Sbjct: 708 Q----EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 67.8 bits (164), Expect = 8e-12
Identities = 58/230 (25%), Positives = 112/230 (48%), Gaps = 17/230 (7%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEA--EVASLNRRIQLVEEELDR 65
E V R+ + +++Q + E+ E++ R+ E + REQ E E ++ + ++ EEE +
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQ---EEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 66 AQE-RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 124
QE ++ +K+ E E+ E ++ E + + EEKM QE +++E + +E +
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 125 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK 184
K E K+ EE + E + E +E ++ +Q K E + Q+E
Sbjct: 627 KIREQEEKI-------REQEEMTQEQEEKMGEQEE--KMCEQEEKMQEQEETMWRQEEKI 677
Query: 185 YEEEIKI--LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
E+E KI +K++E E + E + + E+ + + EE++ Q E+ R
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Score = 67.4 bits (163), Expect = 1e-11
Identities = 56/224 (25%), Positives = 118/224 (52%), Gaps = 21/224 (9%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGER-RAREQAEAEVASLNRRIQLVEEELDRAQER 69
+ KI+ L+++ + E+ E+ ++ E E+ R +E+ + + A + R+ EE++ +E+
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEK 445
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
+ +K+ E+ E E K+ E +++E+M QE ++ E + I + ++ +E+
Sbjct: 446 IREQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ- 501
Query: 130 ARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEI 189
E + + EE+ E + RE +E+IR ++ + EEK ++E+ + EE
Sbjct: 502 -------EEKIRKQEEKVWRQEEKIREQEEKIREQEEK---MWRQEEKIREQEEMWREEE 551
Query: 190 KI-LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
K+ +K+ E E R E E + + E+ I + EE+++ Q E+ R
Sbjct: 552 KMHEQEKIWEEEKRQE-QEDKMWRQEEKIREQEEKVWRQEEKIR 594
Score = 63.2 bits (152), Expect = 2e-10
Identities = 51/236 (21%), Positives = 117/236 (49%), Gaps = 20/236 (8%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEA-EVASLNRRIQLV--EEELDRAQ 67
+ KI+ +++ + E++ R + ++ + + RE+ + E + R+ + + +EE+ R +
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
E++ +K+ + E+ E ++ E + + EEKM QE +++E + + E ++ +E
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 128 -----------EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEE 176
E K+ E + EE+ E + RE +E+ + ++ + EE
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK---MWKQEE 612
Query: 177 KYSQKEDK---YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
K ++E+K EE+I+ +K++E E + E + + E+ + + EE++ Q E
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Score = 62.8 bits (151), Expect = 3e-10
Identities = 62/241 (25%), Positives = 111/241 (46%), Gaps = 32/241 (13%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
QQQ + + E++Q E E + +EQ E ++ +I+ EE++ R +E + +K+
Sbjct: 296 QQQEEKMWRQEEKIQ---EWEEKIQEQEE-KIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQE---------IQLKEAKHIAEEADRKYEE 128
E+ E E M+ E + EEKM QE I+ E K +E R+ EE
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 129 VARKLVIIEGDLERTEERAEL--AESRCREMDEQIRLMDQNL---------KCLSAAEEK 177
++ I +R E+ A++ E + RE +E+IR ++ + + EEK
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471
Query: 178 YSQKEDKYEEEIKI--------LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++E+ + +E KI +K+ E E + E V + E+ I + EE++ Q E
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
Query: 230 R 230
+
Sbjct: 532 K 532
Score = 61.6 bits (148), Expect = 6e-10
Identities = 62/241 (25%), Positives = 117/241 (48%), Gaps = 25/241 (10%)
Query: 7 IEAVKRKIQ----VLQQQADDAEERAERLQREVEGERRAREQAEAEVASL-NRRIQLVEE 61
++ +KRK++ +L QQ AE A+ L +E++ A+ QA+ E L NR Q EE
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAE--ADHLGKELQSVS-AKLQAQVEENELWNRLNQQQEE 300
Query: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEE 121
++ R +E++ +K++E E+ E E ++ E + + EE M +E +++ + + E
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 122 ADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQI----RLMDQNLKCLSAAEEK 177
+ K + E + R EE E + RE++E++ ++ +Q K EEK
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEK 418
Query: 178 YSQKEDKYEEEIKI---------LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQL 228
++E + E+E K+ +K++E E + E + + EK + EE+ Q
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE--EEKRQEQE 476
Query: 229 E 229
E
Sbjct: 477 E 477
Score = 59.7 bits (143), Expect = 2e-09
Identities = 40/183 (21%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ + EE+ R + ++ + R++ E ++ +I+ EE++ +E++ +K+
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137
E E+ E E M + EEKM QE +++E + + K E +K+ E
Sbjct: 636 REQEEMTQEQEEKMG-------EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Query: 138 GDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLK 197
+ EE + E + E +E ++ +Q K E+ Q+E +E+E+++ + K
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Query: 198 EAE 200
E
Sbjct: 747 MQE 749
Score = 57.8 bits (138), Expect = 9e-09
Identities = 55/233 (23%), Positives = 108/233 (46%), Gaps = 21/233 (9%)
Query: 12 RKIQVLQQQADDAEERAERLQREV-EGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
R+ + + +Q EE + Q E+ E + EQ E + ++ EE++ + +E++
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE--IWRQKEKMHEQEEKIRKQEEKV 512
Query: 71 ATALQKLEEAEKAADESERGM-----KVIENRAL-KDEEKMELQEIQLKEAKHIAEE--- 121
+K+ E E+ E E M K+ E + ++EEKM QE +E K +E
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 122 --ADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYS 179
+ K E K+ E + EE+ + E + + +E+IR ++ ++ EEK
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ---EQEEKIR 629
Query: 180 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
++E+K E+ + +E E + E + + E+ + + EE ++ Q E+ R
Sbjct: 630 EQEEKIREQ----EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/230 (21%), Positives = 105/230 (45%), Gaps = 16/230 (6%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ AV + + + ++ + + L E+ E+ + + A L ++QLVE E
Sbjct: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA--DR 124
Q + +KLE A+ + + +A D ELQ + K + E +R
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 125 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLK----CLSAAEEKYSQ 180
++ K+ E ++ EE+ + E + RE +E+IR ++ ++ + EEK +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 181 KED---KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ 227
+E+ + EE+++ + + E E + E + + E+ I +LEE+++ Q
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403
Score = 55.8 bits (133), Expect = 3e-08
Identities = 42/173 (24%), Positives = 86/173 (49%), Gaps = 7/173 (4%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E V R+ + +++Q + +E+ E++ ++ E + REQ E ++ +I+ EE++ +
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQ---EEKIREQEE-KIQEQEEKIREQEEKIREQE 639
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
E +K+ E E+ E E M+ E + EEK+ QE +++E + E + +
Sbjct: 640 EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
Query: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
E K+ E + EE+ + E + R +E ++ +Q ++ L EEK +
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE--KMWEQEVR-LRQQEEKMQE 749
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 72.8 bits (177), Expect = 3e-13
Identities = 55/232 (23%), Positives = 116/232 (50%), Gaps = 12/232 (5%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E ++ + + +Q E+ +R + E E+ R++ EA++ +I+ EE++ +
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
+++ +K+ E EK +E +R + E ++E+ E +EI ++ K +E RK E
Sbjct: 437 KKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
Query: 128 EVA----RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLK----CLSAAEEKYS 179
E K+ E + EE+ E + RE +E+IR ++ ++ + EEK
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 180 QKEDKYEEEIKILT--DKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++E+K +E+ K+ +K++E E + + + + E+ I + EE++ Q E
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Score = 70.1 bits (170), Expect = 2e-12
Identities = 57/248 (22%), Positives = 115/248 (46%), Gaps = 33/248 (13%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELD----RA 66
+ K++ L++ + EE+ L+ ++ + + REQ E R Q +E + R
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 421
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD--- 123
+E++ +K+ E EK E K+ E +++EEK + QE ++ + I E+ +
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEE--KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 124 -----------RKYEEVA----RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNL 168
RK EE K+ E + EE+ E + RE +E+IR ++ +
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 169 K----CLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERL 224
+ + EEK ++E+K +E+ +K++ E + E + + ++ I + EE++
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQ-----EKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
Query: 225 YSQLERNR 232
+ Q E+ R
Sbjct: 595 WEQEEKIR 602
Score = 63.5 bits (153), Expect = 2e-10
Identities = 54/226 (23%), Positives = 108/226 (47%), Gaps = 20/226 (8%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
QQQ + + E++Q E E + +EQ E ++ +I+ EE++ R +E + +K+
Sbjct: 296 QQQEEKMWRQEEKIQ---EWEEKIQEQEE-KIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137
E+ E E M+ +E + EEK+ E ++ E + I E+ +++ EE I
Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK-----IR 406
Query: 138 GDLERTEERAEL--AESRCREMDEQIRLMDQNL---------KCLSAAEEKYSQKEDKYE 186
+R E+ A++ E + RE +E+IR ++ + + EEK ++E+ +
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+E KI + + + + K E+ + EE+++ Q E+ R
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512
Score = 63.2 bits (152), Expect = 2e-10
Identities = 57/247 (23%), Positives = 116/247 (46%), Gaps = 22/247 (8%)
Query: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
+ KI+ +++ + E++ R + ++ + + RE+ + + R +EE R QE +
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR----QEEKIREQEEI 477
Query: 71 ATALQKLEEAEKAADESER------GMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 124
+K+ E EK + E+ M E + + EEKM QE +++E + E +
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537
Query: 125 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK 184
K E + E + EE+ + E + R +E+IR ++ ++ +EK ++E+K
Sbjct: 538 KIREQEEMMQEQEEKMGEQEEKMQEQE-KMRRQEEKIREQEEKIR---EQKEKIREQEEK 593
Query: 185 ---YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERN-----RLLSN 236
EE+I+ + ++E E + E + + E+ + + EE++ Q E+ RL
Sbjct: 594 IWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 653
Query: 237 ELKLTLH 243
E K+ H
Sbjct: 654 EEKMQEH 660
Score = 60.8 bits (146), Expect = 1e-09
Identities = 64/245 (26%), Positives = 119/245 (48%), Gaps = 26/245 (10%)
Query: 7 IEAVKRKI---------QVLQQQAD----DAEERAERLQREVEGER---RAREQAEAEVA 50
++ +KRK+ Q LQ +AD + + + +LQ +VE R +Q E ++
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
+IQ EE++ +E++ +K+ E E+ E M E + + EE M +E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 111 QLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMD---EQIRLMDQN 167
+++ + + E + K E+ K+ E E+ E+R E E + RE + EQ M +
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQ 421
Query: 168 LKCLSAAEEKYSQKEDK-YEEEIKI-LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLY 225
+ + EEK ++E K + +E KI +K++E E R E + + + E+ I + EE ++
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE--QEEMWRQEEKIREQEE-IW 478
Query: 226 SQLER 230
Q E+
Sbjct: 479 RQKEK 483
Score = 58.5 bits (140), Expect = 5e-09
Identities = 47/203 (23%), Positives = 99/203 (48%), Gaps = 8/203 (3%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQRE-VEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
E ++ + ++ +Q+ E+ R Q E V + E ++ ++ EE++
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
+E++ +K+ E E+ E E M E + ++++EKM QE +++E + E K
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEK-MQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK-Y 185
E K+ E E+ E+ E+ + + +M EQ M + + + EEK ++E+K +
Sbjct: 588 REQEEKIWEQE---EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 644
Query: 186 EEEIKI--LTDKLKEAETRAEFA 206
E+E+++ +K++E + E A
Sbjct: 645 EQEVRLRQQEEKMQEHQEHLEAA 667
Score = 56.6 bits (135), Expect = 2e-08
Identities = 49/223 (21%), Positives = 101/223 (45%), Gaps = 16/223 (7%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ AV + + + ++ + + L E+ E+ + + A L ++QLVE E
Sbjct: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA--DR 124
Q + +KLE A+ + + +A D ELQ + K + E +R
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 125 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK 184
++ K+ E ++ EE+ + E + RE +E+IR ++ ++ EE +KE+K
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR---RQEEMMWEKEEK 350
Query: 185 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ 227
+ +++ +K E + E + + E+ I +LEE+++ Q
Sbjct: 351 MRRQEEMMWEK----EEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Score = 28.5 bits (62), Expect = 5.6
Identities = 15/86 (17%), Positives = 41/86 (47%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I K KI+ +++ + EE+ + ++ + + E ++ ++Q EE++ R
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 67 QERLATALQKLEEAEKAADESERGMK 92
+E++ +L + E+ E + ++
Sbjct: 640 EEKMWEQEVRLRQQEEKMQEHQEHLE 665
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 72.8 bits (177), Expect = 3e-13
Identities = 54/224 (24%), Positives = 111/224 (49%), Gaps = 10/224 (4%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREV-EGERRAREQAEAEVASLNRRIQLVEEELDRA 66
E + R+ + + +Q EE + Q E+ E + REQ E + +I EE++ +
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE--IWRQKEKIHEQEEKIRKQ 555
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
+E++ +K+ + E+ E E + E + + EEK+ QE +++E + + +E + K
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
E K+ E ++ EE+ E + RE +++IR ++ ++ EE ++E+K
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR---EQEEMMQEQEEKMW 672
Query: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
E+ +K+ E E + + E + + E+ + + E RL Q E+
Sbjct: 673 EQ----EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Score = 69.7 bits (169), Expect = 2e-12
Identities = 57/246 (23%), Positives = 115/246 (46%), Gaps = 29/246 (11%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
E ++ + + +Q E+ +R + E E+ R++ EA++ +I+ EE++ +
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Query: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI-QLKEAKHIAEEADRKY 126
E++ +K+ E EK +E +R + E ++E+ E +EI + KE H EE RK
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 127 EEVA----RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLK------------- 169
EE K+ E + EE+ E + RE +E+IR ++ ++
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 170 -----CLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERL 224
+ EEK ++E+K + +K++E E + E + + E+ + + EE++
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQ----EEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Query: 225 YSQLER 230
+ Q E+
Sbjct: 672 WEQEEK 677
Score = 67.4 bits (163), Expect = 1e-11
Identities = 56/251 (22%), Positives = 122/251 (48%), Gaps = 21/251 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRARE---QAEAEVASLNRRIQLVEEELD 64
E ++R+ +++ ++ + + E + + E RR E + E ++ L ++ E+E
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKI 453
Query: 65 RAQERLATALQKLEEAEKAADE------SERGMKVIENRALKDEEKMELQEIQLKEAKHI 118
R QE +K+ E EK ++ E ++ E + + EEKM QE ++ E + I
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 119 AEEADRKYEEV---ARKLVIIEGDLERTEERAELAESRCREMDEQI-----RLMDQNLKC 170
EE R+ +E + + + ++ R +E+ E + R+ +E++ ++ DQ K
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Query: 171 LSAAEEKYSQKED--KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQL 228
E+ + Q+E + EE+I+ +K++E E + E + + E+ + + EE++ Q
Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Query: 229 ERNRLLSNELK 239
E+ R +++
Sbjct: 634 EKMRRQEEKIR 644
Score = 67.0 bits (162), Expect = 1e-11
Identities = 57/240 (23%), Positives = 120/240 (50%), Gaps = 18/240 (7%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREV---EGERRAREQAEA---EVASLNRRIQLVEE 61
E +++ + +++Q E+ A+ ++E E E + REQ E + ++ + ++ EE
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516
Query: 62 ELDRAQERLATALQKLEEAEKA------ADESERGMKVIENRALKDEEKMELQEIQLKEA 115
E + QE + +K+ E E+ E E ++ E + + EEKM QE +++E
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576
Query: 116 KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAE 175
+ E+ R+ E++ + I E+ E+ E+ + + +M EQ M + + + E
Sbjct: 577 E---EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Query: 176 EKYSQKEDK---YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
EK ++E+K E++I+ +K++E E + E + + E+ + + EE++ Q E+ R
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Score = 65.5 bits (158), Expect = 4e-11
Identities = 57/258 (22%), Positives = 123/258 (47%), Gaps = 19/258 (7%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLV---EEELD 64
E ++ + +Q+Q + E+ E+++ + E RR E + + R+ +++ EE++
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRA----LKDEEKMELQEIQLKEAKHIAE 120
R +E + +K+ E E+ E E+ + E R ++++EK + QE ++ +
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Query: 121 EADRKYEEVARKL-----VIIEGDLERTEERAELAESRCREMDEQIRLMDQ---NLKCLS 172
E + K E K+ I E + R EE+ + E R+ +E+IR ++ + +
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKIH 546
Query: 173 AAEEKYSQKEDKY---EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
EEK ++E+K EE++ +K++E E + E + + E+ I + EE++ Q E
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Query: 230 RNRLLSNELKLTLHDLCD 247
+ ++ +C+
Sbjct: 607 MTQEQEEKMGEQEEKMCE 624
Score = 62.4 bits (150), Expect = 4e-10
Identities = 45/201 (22%), Positives = 99/201 (49%), Gaps = 16/201 (7%)
Query: 12 RKIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDRAQE 68
R+ + + +Q + E+ E+++++ E R E+ E ++ ++ EE++ +E
Sbjct: 533 REQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
++ +K+ E E+ E E M E + + EEKM+ QE +++ + E ++K E
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652
Query: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK-YEE 187
K+ E+ E+ + + +M EQ M + + + EEK ++E+K +E+
Sbjct: 653 QEEKI----------REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 188 EIKI--LTDKLKEAETRAEFA 206
E+++ +K++E + E A
Sbjct: 703 EVRLRQQEEKMQEHQEHLEAA 723
Score = 62.0 bits (149), Expect = 5e-10
Identities = 60/243 (24%), Positives = 117/243 (48%), Gaps = 22/243 (9%)
Query: 7 IEAVKRKI---------QVLQQQAD----DAEERAERLQREVEGER---RAREQAEAEVA 50
++ +KRK+ Q LQ +AD + + + +LQ +VE R +Q E ++
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364
Query: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
+IQ EE++ +E++ +K+ E E+ E M E + + EE M +E
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 111 QLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCRE--MDEQIRLMDQNL 168
+++ + + E + K E+ K+ E E+ E+R E + R +E +++ ++ Q
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 169 KCLSAAEEKYSQKEDKYEEEIKI-LTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ 227
K E+ Q+E + +E KI +K++E E R E + + + E+ I + EE ++ Q
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE--QEEMWRQEEKIREQEE-IWRQ 541
Query: 228 LER 230
E+
Sbjct: 542 KEK 544
Score = 58.5 bits (140), Expect = 5e-09
Identities = 44/184 (23%), Positives = 89/184 (48%), Gaps = 8/184 (4%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEG----ERRAREQAEAEVASLNRRIQLVEEEL 63
E + R+ + + +Q + ++ E++ R+ E E + REQ E +V +I+ EE++
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE-KVWRQEEKIREQEEKI 594
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
+E++ + +E E+ E E M E + + EEKM QE +++E + E +
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
K E + E + EE+ E + +E +E++R ++ + E + Q+E+
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK---MWEQEVRLRQQEE 711
Query: 184 KYEE 187
K +E
Sbjct: 712 KMQE 715
Score = 56.6 bits (135), Expect = 2e-08
Identities = 49/223 (21%), Positives = 101/223 (45%), Gaps = 16/223 (7%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ AV + + + ++ + + L E+ E+ + + A L ++QLVE E
Sbjct: 242 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 301
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA--DR 124
Q + +KLE A+ + + +A D ELQ + K + E +R
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNR 354
Query: 125 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK 184
++ K+ E ++ EE+ + E + RE +E+IR ++ ++ EE +KE+K
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR---RQEEMMWEKEEK 411
Query: 185 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ 227
+ +++ +K E + E + + E+ I +LEE+++ Q
Sbjct: 412 MRRQEEMMWEK----EEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Score = 56.2 bits (134), Expect = 3e-08
Identities = 40/166 (24%), Positives = 81/166 (48%), Gaps = 5/166 (3%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEG----ERRAREQAEAEVASLNRRIQLVEEEL 63
E + R+ + + Q + E+ E++ R+ E E + REQ E ++ Q EE++
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE-KIREQEEMTQEQEEKM 615
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
+E++ +K++E E+ E ++ E + + EEK+ QE ++E + E +
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLK 169
K E K+ E + R EE+ E R R+ +E+++ ++L+
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 72.0 bits (175), Expect = 4e-13
Identities = 70/243 (28%), Positives = 112/243 (46%), Gaps = 30/243 (12%)
Query: 13 KIQVLQQQADDAEERAE----RLQREVEG-----------ERRAREQAEAEVASLNRRIQ 57
K++ LQ + + + E +LQ EVE E R REQ E + R++
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEE-RLREQEERLR 216
Query: 58 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 117
EE L +ERL ++L E E+ E E ++ E R + EE++ QE +L+E +
Sbjct: 217 EQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEE 276
Query: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
E + + E +L E L EER E R E +E++R ++ L +EK
Sbjct: 277 RLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL----CEQEK 332
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE 237
+E EE +KL E E R E ER + + E+ ++++EE LE+ RL +
Sbjct: 333 LPGQERLLEE-----VEKLLEQERRQEEQERLLER-ERLLEEVEE----LLEQERLRQQD 382
Query: 238 LKL 240
+L
Sbjct: 383 ERL 385
Score = 66.6 bits (161), Expect = 2e-11
Identities = 70/245 (28%), Positives = 114/245 (46%), Gaps = 20/245 (8%)
Query: 8 EAVKRKIQVLQQQADDAEERAERL----QREVEGERRAREQAEAEVASLNRRIQLVEEEL 63
E ++ + + L++Q + E+ ERL +R E E R REQ E + R++ EE L
Sbjct: 199 ERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEE-RLCEQEERLREHEERL 257
Query: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
+ERL ++L E E+ E E + E R + EE++ QE +L+E + E +
Sbjct: 258 CEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE 317
Query: 124 RKYEEVARKLVIIE--GDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 181
+ E +L E ER E E + R +EQ RL+++ + L EE Q+
Sbjct: 318 ERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERE-RLLEEVEELLEQE 376
Query: 182 EDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRL----LSNE 237
+ ++E +L + ET E + +LE+ ++ E LY Q R L+NE
Sbjct: 377 RLRQQDE------RLWQQETLQEL--ERLRELERMLELGWEALYEQRAEPRSGFEELNNE 428
Query: 238 LKLTL 242
K TL
Sbjct: 429 NKSTL 433
Score = 52.0 bits (123), Expect = 5e-07
Identities = 55/258 (21%), Positives = 112/258 (43%), Gaps = 19/258 (7%)
Query: 2 AGITTIEAVKRKIQVLQQQADDAEERAERLQREVEG-ERRAREQAEAEVASLNRRIQLVE 60
A TT+E ++ + Q L D + +L + R ++E+ + E+ + + + +
Sbjct: 79 ASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLF 138
Query: 61 EELDRAQERLA----TALQKLEEAEKAADESERGMKVIENRALKDEEKMEL-------QE 109
+ ++ E LA K+E+ + + + ++ + + + E ++ QE
Sbjct: 139 KLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE 198
Query: 110 IQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLK 169
+L+E + E + + E +L E L EER E R E +E++R ++ L
Sbjct: 199 ERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERL- 257
Query: 170 CLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
EE+ ++E++ E+ ++L E E R E + + E+ + + EERL Q E
Sbjct: 258 --CEQEERLCEQEERLREQ----EERLHEQEERLCEQEERLREQEERLCEQEERLREQEE 311
Query: 230 RNRLLSNELKLTLHDLCD 247
R L+ LC+
Sbjct: 312 RLCEQEERLREQEERLCE 329
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A++ + + + Q A+E AERL+R+V+ E + + QAE E+AS V+ E + A
Sbjct: 1475 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELAS------RVKAEAEAA 1528
Query: 67 QERLATALQKLEEAEKAADESERGMKVIE-------NRALKDEEKMELQEIQLKEAKHIA 119
+E+ ALQ LEE A+E+ER ++ E AL+ ++ E+Q K A
Sbjct: 1529 REK-QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1587
Query: 120 EEA--DRKYEEVARKLVIIEGDLE-RTEERAELAESR---CREMDEQIRLMDQNLKCLSA 173
+ A +R +E + + + E R +++AE +R RE++ ++ L+
Sbjct: 1588 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1647
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
AEE QK E K + +EA R + E++V + E +LE++
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1697
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/242 (24%), Positives = 112/242 (46%), Gaps = 32/242 (13%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRARE-------QAEAEVASLNRRIQLVEE 61
AV++K Q LQQ + ++L+ E E RRA E QAE E A R+++ E
Sbjct: 2057 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2116
Query: 62 ELDRAQERLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHI 118
A+E+ Q AEK E+E+ E AL+ + + + ++++ K
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK---QAADAEMEKHKKF 2173
Query: 119 AEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKY 178
AE+ R+ +V ++L + LE T D Q L+D+ L+ L A +
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEET--------------DHQKNLLDEELQRLKAEATEA 2219
Query: 179 SQKEDKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLS 235
+++ + EEE +++ ++L + + R E R++ +K D+ + L + E+ + ++
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK--DNTQRFLQEEAEKMKQVA 2277
Query: 236 NE 237
E
Sbjct: 2278 EE 2279
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/259 (23%), Positives = 124/259 (47%), Gaps = 35/259 (13%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQR-----------EVEGERR---AREQAE 46
M + +K + ++LQQQ + A+E+A RLQ E +G +R A Q +
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2375
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 106
E+++ R++L E+ RAQ R E+A++ ++E + + L +EK+
Sbjct: 2376 LEMSAEAERLKLRVAEMSRAQARAE------EDAQRFRKQAEEIGEKLHRTELATQEKVT 2429
Query: 107 LQ---EIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREM----DE 159
L EIQ +++ H +A+R E +A +E + E+ ++ A+L + + EM E
Sbjct: 2430 LVQTLEIQRQQSDH---DAERLREAIAE----LEREKEKLQQEAKLLQLKSEEMQTVQQE 2482
Query: 160 QIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE-TRAEFAERSVAKLEKTID 218
Q+ Q L+ +E+ + +++ E+ K ++L + E +A+ + ++ ++
Sbjct: 2483 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQME 2542
Query: 219 DLEERLYSQLERNRLLSNE 237
+RL + +E R +E
Sbjct: 2543 QERQRLVASMEEARRRQHE 2561
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 16/240 (6%)
Query: 11 KRKIQV-LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
KR IQ LQQ +E + R+ E R+R + E E+ + +++ E + A+
Sbjct: 1415 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1474
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
L + EEAE +++ + + + + ++ E++L EA R+ +
Sbjct: 1475 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1534
Query: 130 ARKLVIIEGDLERTEERAELAE-SRCREMDEQIRLMDQNLKC-----LSAAEEKYSQKED 183
+ L + E E R AE R R++ + ++ + ++ EK +Q E
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE-LKLTL 242
+EE + +EAE RA+ A+ E+ ++ E +LER +L +NE L+L L
Sbjct: 1595 SLQEEHVAVAQLREEAERRAQ----QQAEAERAREEAER----ELERWQLKANEALRLRL 1646
Score = 58.2 bits (139), Expect = 7e-09
Identities = 62/241 (25%), Positives = 119/241 (49%), Gaps = 31/241 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVE--GERRAR-EQAEAEVASLNRRIQLVEEELD 64
E +K ++ + + AEE A+R +++ E GE+ R E A E +L + +++ ++ D
Sbjct: 2383 ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2442
Query: 65 RAQERLATALQKLE-EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
ERL A+ +LE E EK E+ K+++ LK EE +Q+ QL + +++
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEA----KLLQ---LKSEEMQTVQQEQLLQETQALQQS- 2494
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
++ K +++ + +E+A+L EQ+ D+ K EE+ Q++
Sbjct: 2495 ----FLSEKDSLLQRERFIEQEKAKL---------EQL-FQDEVAKAQQLREEQQRQQQ- 2539
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ----LERNRLLSNELK 239
+ E+E + L ++EA R AE V + ++ + LE++ Q E N+ L +L+
Sbjct: 2540 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQ 2599
Query: 240 L 240
L
Sbjct: 2600 L 2600
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 23/227 (10%)
Query: 19 QQADDAEERAERLQREVEGERRAREQAEAEV------ASLNRRIQLVEEELDRAQERLAT 72
Q ++AE RA Q++ E E RARE+AE E+ A+ R++L EE+ + Q+ LA
Sbjct: 1605 QLREEAERRA---QQQAEAE-RAREEAERELERWQLKANEALRLRLQAEEVAQ-QKSLAQ 1659
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
A EAEK +E+ER + + + EL E +L++ + +AE ++ ++
Sbjct: 1660 A-----EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1714
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
L+ + + E+ E++ +L E + + Q + L A K + E E+ +L
Sbjct: 1715 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-----RAEMEV-LL 1768
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
K + E +E+S +LE E L + R R L+ E K
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAK 1814
Score = 54.7 bits (130), Expect = 7e-08
Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ +AEER ++ E R R+ A EV L +++ +RA++ A LQ
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2039
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVI 135
+EA + ++E + + E + LQ+ Q L + + AE A R EE V
Sbjct: 2040 QEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2099
Query: 136 IEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKEDKYEEEIKI 191
E + ++ + E AE + +EQ + Q K AE++ +++ + ++
Sbjct: 2100 AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2159
Query: 192 LTDKLKEAETRAEFAE---RSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
E E +FAE R A++E+ + L +L + LL EL+
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210
Score = 53.1 bits (126), Expect = 2e-07
Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 36/218 (16%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+QQ EE RLQRE + R++ EAE+A + ++++ RA+E
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE--------- 1776
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR---KYEEVARKLV 134
E+R+ ++ K L E + + +AEEA R EE R+
Sbjct: 1777 -----------------ESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKRQRQ 1818
Query: 135 IIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD 194
+ E D R AE R + E++ + + + + AE +KE + E ++ D
Sbjct: 1819 LAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Query: 195 KLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+ + E A + A +E+ + L + S+LER +
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1910
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 27/253 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ ++ +++ Q + +E +RL+ E R R Q E E+ S+ R+Q+ EEL +
Sbjct: 2188 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV--RVQM--EELSKL 2243
Query: 67 QERLATALQKL-------------EEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
+ R+ + L EEAEK +E + + A + +L E L
Sbjct: 2244 KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLA 2302
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
+ + +AE+ ++ + ++ ++ + E +++ ELA+ + R + E M Q L +
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2362
Query: 174 AEEKYSQKEDKYEEEIKILTDKLK----EAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++ + E + + E+ ++LK E AE + K +++ E+L+
Sbjct: 2363 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH---- 2418
Query: 230 RNRLLSNELKLTL 242
R L + E K+TL
Sbjct: 2419 RTELATQE-KVTL 2430
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/246 (20%), Positives = 116/246 (47%), Gaps = 22/246 (8%)
Query: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERR-------AREQAEAEVASLNRRIQL 58
T+ ++ + ++ +QQ + ER ++ +E +R+ A+ QAE E L +R+Q
Sbjct: 1340 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ- 1398
Query: 59 VEEELDRAQERLATA----------LQKLEEAEKAADESE-RGMKVIENRALKDEEKMEL 107
EE+ R +E A LQ+L ++ +A +++ R + E L+ EE++ +
Sbjct: 1399 --EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1456
Query: 108 QEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQN 167
+QL+ + A+ + + + + E + +E AE + ++ ++ R +
Sbjct: 1457 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1516
Query: 168 LKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAK-LEKTIDDLEERLYS 226
L AE + ++++ + + ++ L + +EAE R AE A+ ++ ++ + +
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
Query: 227 QLERNR 232
+L+ R
Sbjct: 1577 ELQSKR 1582
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/218 (25%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A+K + + E R++ E R++EQAE E A R+ QL EE R
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRR 1983
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAK---HIAEEAD 123
+E + L E+AA + + ++ +E K EE L+E +E+ +A+EA
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 124 RK---YEEVARKLVI--IEGDLERTEERAELAESRCR-EMDEQIRLMDQNLKCLSAAEEK 177
+K EE A + E +L++T ++ + + R E + R ++ + AE +
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
+Q + EE ++ ++A+ RA+ A+ + KL K
Sbjct: 2104 AAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRK 2140
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/245 (21%), Positives = 107/245 (43%), Gaps = 16/245 (6%)
Query: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDR---- 65
K + ++ +E+ +RL+ E R E+A A R+ QL EE+ R
Sbjct: 1771 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1830
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIEN-----RALKDEEKMELQEIQLKEAKHIAE 120
A+ LA L + EA + E+E +K E R L ++E + + ++ + A+H A+
Sbjct: 1831 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1890
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+R +A+ + +LER + E + R+++E+I + + + +A + +
Sbjct: 1891 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL 1946
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + + ++AE A + A+ E+ + EER+ L + + K
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2006
Query: 241 TLHDL 245
L ++
Sbjct: 2007 ALEEV 2011
Score = 48.1 bits (113), Expect = 7e-06
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 33/222 (14%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQL-------VEEE 62
++ ++ L++ +D ER + L VE R R Q E E+ +L + +E E
Sbjct: 1891 IEERLAQLRKASDSELERQKGL---VEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1947
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
L R + L+ E+AE ++ R L EE+ +E + + K +A E
Sbjct: 1948 LGRIRSNAEDTLRSKEQAE---------LEAARQRQLAAEEERRRREAEERVQKSLAAE- 1997
Query: 123 DRKYEEVARKLVIIEGDLERTEERAE----LAESRCREMDEQIRLMDQNLKCLSAAEEK- 177
EE AR+ ++ER + + E L E +E Q++L + + AEEK
Sbjct: 1998 ----EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2053
Query: 178 ----YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
QKE + ++ ++ L + AE A R+ + E+
Sbjct: 2054 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/224 (23%), Positives = 100/224 (44%), Gaps = 28/224 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA-EAEVASLNRRIQLVEEELDRA 66
E + ++ Q LQQ ++ + +R +E E+ EQ + EVA + Q + EE R
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA----KAQQLREEQQRQ 2537
Query: 67 QERLATALQKL----EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Q+++ Q+L EEA + E+E G++ K EE +L++ + ++ + +AEE
Sbjct: 2538 QQQMEQERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEEN 2591
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
R E++ L + RA LA S Q+ A + ++ E
Sbjct: 2592 QRLREQL---------QLLEEQHRAALAHSE-EVTASQVAATKTLPNGRDALDGPAAEAE 2641
Query: 183 DKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
++ + K+ +L+EA + + +A+ T+D+L R
Sbjct: 2642 PEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARR 2685
Score = 41.2 bits (95), Expect = 8e-04
Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 57/285 (20%)
Query: 2 AGITTIEAVKRKIQVLQQQAD--------------DAEERAERLQREVEGERRAR-EQAE 46
A + +EA K ++ L+ QA+ A+E ERLQ+ GER E+
Sbjct: 1120 ATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQR-HGERDVEVERWR 1178
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-------------ESERGMKV 93
VA L R Q V + D Q L ++L ++AD E + M +
Sbjct: 1179 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1238
Query: 94 IENRALKDEEKME---LQEIQ-----LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 145
+++A++++ + E L+EI+ ++E + A++ ++ +LV + LE
Sbjct: 1239 ADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVAS 1298
Query: 146 RAEL------AESRCRE-------MDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
A+ +ES +E E L Q +K +S + ++E E++
Sbjct: 1299 PAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE 1358
Query: 193 TDKLKEAETR-------AEFAERSVAKLEKTIDDLEERLYSQLER 230
++L E E AE ++ A+ E+ +L++R+ ++ R
Sbjct: 1359 RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A++ + + + Q A+E AERL+R+V+ E + + QAE E+AS V+ E + A
Sbjct: 1479 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELAS------RVKAEAEAA 1532
Query: 67 QERLATALQKLEEAEKAADESERGMKVIE-------NRALKDEEKMELQEIQLKEAKHIA 119
+E+ ALQ LEE A+E+ER ++ E AL+ ++ E+Q K A
Sbjct: 1533 REK-QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1591
Query: 120 EEA--DRKYEEVARKLVIIEGDLE-RTEERAELAESR---CREMDEQIRLMDQNLKCLSA 173
+ A +R +E + + + E R +++AE +R RE++ ++ L+
Sbjct: 1592 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1651
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
AEE QK E K + +EA R + E++V + E +LE++
Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1701
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/242 (24%), Positives = 112/242 (46%), Gaps = 32/242 (13%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRARE-------QAEAEVASLNRRIQLVEE 61
AV++K Q LQQ + ++L+ E E RRA E QAE E A R+++ E
Sbjct: 2061 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2120
Query: 62 ELDRAQERLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHI 118
A+E+ Q AEK E+E+ E AL+ + + + ++++ K
Sbjct: 2121 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK---QAADAEMEKHKKF 2177
Query: 119 AEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKY 178
AE+ R+ +V ++L + LE T D Q L+D+ L+ L A +
Sbjct: 2178 AEQTLRQKAQVEQELTTLRLQLEET--------------DHQKNLLDEELQRLKAEATEA 2223
Query: 179 SQKEDKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLS 235
+++ + EEE +++ ++L + + R E R++ +K D+ + L + E+ + ++
Sbjct: 2224 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK--DNTQRFLQEEAEKMKQVA 2281
Query: 236 NE 237
E
Sbjct: 2282 EE 2283
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/259 (23%), Positives = 124/259 (47%), Gaps = 35/259 (13%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQR-----------EVEGERR---AREQAE 46
M + +K + ++LQQQ + A+E+A RLQ E +G +R A Q +
Sbjct: 2320 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2379
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 106
E+++ R++L E+ RAQ R E+A++ ++E + + L +EK+
Sbjct: 2380 LEMSAEAERLKLRVAEMSRAQARAE------EDAQRFRKQAEEIGEKLHRTELATQEKVT 2433
Query: 107 LQ---EIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREM----DE 159
L EIQ +++ H +A+R E +A +E + E+ ++ A+L + + EM E
Sbjct: 2434 LVQTLEIQRQQSDH---DAERLREAIAE----LEREKEKLQQEAKLLQLKSEEMQTVQQE 2486
Query: 160 QIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE-TRAEFAERSVAKLEKTID 218
Q+ Q L+ +E+ + +++ E+ K ++L + E +A+ + ++ ++
Sbjct: 2487 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQME 2546
Query: 219 DLEERLYSQLERNRLLSNE 237
+RL + +E R +E
Sbjct: 2547 QERQRLVASMEEARRRQHE 2565
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 16/240 (6%)
Query: 11 KRKIQV-LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
KR IQ LQQ +E + R+ E R+R + E E+ + +++ E + A+
Sbjct: 1419 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1478
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
L + EEAE +++ + + + + ++ E++L EA R+ +
Sbjct: 1479 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1538
Query: 130 ARKLVIIEGDLERTEERAELAE-SRCREMDEQIRLMDQNLKC-----LSAAEEKYSQKED 183
+ L + E E R AE R R++ + ++ + ++ EK +Q E
Sbjct: 1539 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1598
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE-LKLTL 242
+EE + +EAE RA+ A+ E+ ++ E +LER +L +NE L+L L
Sbjct: 1599 SLQEEHVAVAQLREEAERRAQ----QQAEAERAREEAER----ELERWQLKANEALRLRL 1650
Score = 58.2 bits (139), Expect = 7e-09
Identities = 62/241 (25%), Positives = 119/241 (49%), Gaps = 31/241 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVE--GERRAR-EQAEAEVASLNRRIQLVEEELD 64
E +K ++ + + AEE A+R +++ E GE+ R E A E +L + +++ ++ D
Sbjct: 2387 ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2446
Query: 65 RAQERLATALQKLE-EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
ERL A+ +LE E EK E+ K+++ LK EE +Q+ QL + +++
Sbjct: 2447 HDAERLREAIAELEREKEKLQQEA----KLLQ---LKSEEMQTVQQEQLLQETQALQQS- 2498
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
++ K +++ + +E+A+L EQ+ D+ K EE+ Q++
Sbjct: 2499 ----FLSEKDSLLQRERFIEQEKAKL---------EQL-FQDEVAKAQQLREEQQRQQQ- 2543
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ----LERNRLLSNELK 239
+ E+E + L ++EA R AE V + ++ + LE++ Q E N+ L +L+
Sbjct: 2544 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQ 2603
Query: 240 L 240
L
Sbjct: 2604 L 2604
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 23/227 (10%)
Query: 19 QQADDAEERAERLQREVEGERRAREQAEAEV------ASLNRRIQLVEEELDRAQERLAT 72
Q ++AE RA Q++ E E RARE+AE E+ A+ R++L EE+ + Q+ LA
Sbjct: 1609 QLREEAERRA---QQQAEAE-RAREEAERELERWQLKANEALRLRLQAEEVAQ-QKSLAQ 1663
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
A EAEK +E+ER + + + EL E +L++ + +AE ++ ++
Sbjct: 1664 A-----EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1718
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
L+ + + E+ E++ +L E + + Q + L A K + E E+ +L
Sbjct: 1719 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-----RAEMEV-LL 1772
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
K + E +E+S +LE E L + R R L+ E K
Sbjct: 1773 ASKARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAK 1818
Score = 54.7 bits (130), Expect = 7e-08
Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ +AEER ++ E R R+ A EV L +++ +RA++ A LQ
Sbjct: 1984 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2043
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVI 135
+EA + ++E + + E + LQ+ Q L + + AE A R EE V
Sbjct: 2044 QEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2103
Query: 136 IEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKEDKYEEEIKI 191
E + ++ + E AE + +EQ + Q K AE++ +++ + ++
Sbjct: 2104 AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2163
Query: 192 LTDKLKEAETRAEFAE---RSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
E E +FAE R A++E+ + L +L + LL EL+
Sbjct: 2164 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2214
Score = 53.1 bits (126), Expect = 2e-07
Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 36/218 (16%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+QQ EE RLQRE + R++ EAE+A + ++++ RA+E
Sbjct: 1730 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE--------- 1780
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR---KYEEVARKLV 134
E+R+ ++ K L E + + +AEEA R EE R+
Sbjct: 1781 -----------------ESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKRQRQ 1822
Query: 135 IIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD 194
+ E D R AE R + E++ + + + + AE +KE + E ++ D
Sbjct: 1823 LAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1876
Query: 195 KLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+ + E A + A +E+ + L + S+LER +
Sbjct: 1877 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1914
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 27/253 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ ++ +++ Q + +E +RL+ E R R Q E E+ S+ R+Q+ EEL +
Sbjct: 2192 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV--RVQM--EELSKL 2247
Query: 67 QERLATALQKL-------------EEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
+ R+ + L EEAEK +E + + A + +L E L
Sbjct: 2248 KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLA 2306
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
+ + +AE+ ++ + ++ ++ + E +++ ELA+ + R + E M Q L +
Sbjct: 2307 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2366
Query: 174 AEEKYSQKEDKYEEEIKILTDKLK----EAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++ + E + + E+ ++LK E AE + K +++ E+L+
Sbjct: 2367 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH---- 2422
Query: 230 RNRLLSNELKLTL 242
R L + E K+TL
Sbjct: 2423 RTELATQE-KVTL 2434
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/246 (20%), Positives = 116/246 (47%), Gaps = 22/246 (8%)
Query: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERR-------AREQAEAEVASLNRRIQL 58
T+ ++ + ++ +QQ + ER ++ +E +R+ A+ QAE E L +R+Q
Sbjct: 1344 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ- 1402
Query: 59 VEEELDRAQERLATA----------LQKLEEAEKAADESE-RGMKVIENRALKDEEKMEL 107
EE+ R +E A LQ+L ++ +A +++ R + E L+ EE++ +
Sbjct: 1403 --EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1460
Query: 108 QEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQN 167
+QL+ + A+ + + + + E + +E AE + ++ ++ R +
Sbjct: 1461 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1520
Query: 168 LKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAK-LEKTIDDLEERLYS 226
L AE + ++++ + + ++ L + +EAE R AE A+ ++ ++ + +
Sbjct: 1521 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1580
Query: 227 QLERNR 232
+L+ R
Sbjct: 1581 ELQSKR 1586
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/218 (25%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A+K + + E R++ E R++EQAE E A R+ QL EE R
Sbjct: 1931 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRR 1987
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAK---HIAEEAD 123
+E + L E+AA + + ++ +E K EE L+E +E+ +A+EA
Sbjct: 1988 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2047
Query: 124 RK---YEEVARKLVI--IEGDLERTEERAELAESRCR-EMDEQIRLMDQNLKCLSAAEEK 177
+K EE A + E +L++T ++ + + R E + R ++ + AE +
Sbjct: 2048 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2107
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
+Q + EE ++ ++A+ RA+ A+ + KL K
Sbjct: 2108 AAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRK 2144
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/245 (21%), Positives = 107/245 (43%), Gaps = 16/245 (6%)
Query: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDR---- 65
K + ++ +E+ +RL+ E R E+A A R+ QL EE+ R
Sbjct: 1775 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1834
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIEN-----RALKDEEKMELQEIQLKEAKHIAE 120
A+ LA L + EA + E+E +K E R L ++E + + ++ + A+H A+
Sbjct: 1835 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1894
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+R +A+ + +LER + E + R+++E+I + + + +A + +
Sbjct: 1895 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL 1950
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + + ++AE A + A+ E+ + EER+ L + + K
Sbjct: 1951 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2010
Query: 241 TLHDL 245
L ++
Sbjct: 2011 ALEEV 2015
Score = 48.1 bits (113), Expect = 7e-06
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 33/222 (14%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQL-------VEEE 62
++ ++ L++ +D ER + L VE R R Q E E+ +L + +E E
Sbjct: 1895 IEERLAQLRKASDSELERQKGL---VEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1951
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
L R + L+ E+AE ++ R L EE+ +E + + K +A E
Sbjct: 1952 LGRIRSNAEDTLRSKEQAE---------LEAARQRQLAAEEERRRREAEERVQKSLAAE- 2001
Query: 123 DRKYEEVARKLVIIEGDLERTEERAE----LAESRCREMDEQIRLMDQNLKCLSAAEEK- 177
EE AR+ ++ER + + E L E +E Q++L + + AEEK
Sbjct: 2002 ----EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2057
Query: 178 ----YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
QKE + ++ ++ L + AE A R+ + E+
Sbjct: 2058 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2099
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/224 (23%), Positives = 100/224 (44%), Gaps = 28/224 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA-EAEVASLNRRIQLVEEELDRA 66
E + ++ Q LQQ ++ + +R +E E+ EQ + EVA + Q + EE R
Sbjct: 2486 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA----KAQQLREEQQRQ 2541
Query: 67 QERLATALQKL----EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Q+++ Q+L EEA + E+E G++ K EE +L++ + ++ + +AEE
Sbjct: 2542 QQQMEQERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEEN 2595
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
R E++ L + RA LA S Q+ A + ++ E
Sbjct: 2596 QRLREQL---------QLLEEQHRAALAHSE-EVTASQVAATKTLPNGRDALDGPAAEAE 2645
Query: 183 DKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
++ + K+ +L+EA + + +A+ T+D+L R
Sbjct: 2646 PEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARR 2689
Score = 41.2 bits (95), Expect = 8e-04
Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 57/285 (20%)
Query: 2 AGITTIEAVKRKIQVLQQQAD--------------DAEERAERLQREVEGERRAR-EQAE 46
A + +EA K ++ L+ QA+ A+E ERLQ+ GER E+
Sbjct: 1124 ATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQR-HGERDVEVERWR 1182
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-------------ESERGMKV 93
VA L R Q V + D Q L ++L ++AD E + M +
Sbjct: 1183 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1242
Query: 94 IENRALKDEEKME---LQEIQ-----LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 145
+++A++++ + E L+EI+ ++E + A++ ++ +LV + LE
Sbjct: 1243 ADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVAS 1302
Query: 146 RAEL------AESRCRE-------MDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
A+ +ES +E E L Q +K +S + ++E E++
Sbjct: 1303 PAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE 1362
Query: 193 TDKLKEAETR-------AEFAERSVAKLEKTIDDLEERLYSQLER 230
++L E E AE ++ A+ E+ +L++R+ ++ R
Sbjct: 1363 RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1407
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A++ + + + Q A+E AERL+R+V+ E + + QAE E+AS V+ E + A
Sbjct: 1475 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELAS------RVKAEAEAA 1528
Query: 67 QERLATALQKLEEAEKAADESERGMKVIE-------NRALKDEEKMELQEIQLKEAKHIA 119
+E+ ALQ LEE A+E+ER ++ E AL+ ++ E+Q K A
Sbjct: 1529 REK-QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1587
Query: 120 EEA--DRKYEEVARKLVIIEGDLE-RTEERAELAESR---CREMDEQIRLMDQNLKCLSA 173
+ A +R +E + + + E R +++AE +R RE++ ++ L+
Sbjct: 1588 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1647
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
AEE QK E K + +EA R + E++V + E +LE++
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1697
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/242 (24%), Positives = 112/242 (46%), Gaps = 32/242 (13%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRARE-------QAEAEVASLNRRIQLVEE 61
AV++K Q LQQ + ++L+ E E RRA E QAE E A R+++ E
Sbjct: 2057 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2116
Query: 62 ELDRAQERLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHI 118
A+E+ Q AEK E+E+ E AL+ + + + ++++ K
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK---QAADAEMEKHKKF 2173
Query: 119 AEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKY 178
AE+ R+ +V ++L + LE T D Q L+D+ L+ L A +
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEET--------------DHQKNLLDEELQRLKAEATEA 2219
Query: 179 SQKEDKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLS 235
+++ + EEE +++ ++L + + R E R++ +K D+ + L + E+ + ++
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK--DNTQRFLQEEAEKMKQVA 2277
Query: 236 NE 237
E
Sbjct: 2278 EE 2279
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/259 (23%), Positives = 124/259 (47%), Gaps = 35/259 (13%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQR-----------EVEGERR---AREQAE 46
M + +K + ++LQQQ + A+E+A RLQ E +G +R A Q +
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2375
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 106
E+++ R++L E+ RAQ R E+A++ ++E + + L +EK+
Sbjct: 2376 LEMSAEAERLKLRVAEMSRAQARAE------EDAQRFRKQAEEIGEKLHRTELATQEKVT 2429
Query: 107 LQ---EIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREM----DE 159
L EIQ +++ H +A+R E +A +E + E+ ++ A+L + + EM E
Sbjct: 2430 LVQTLEIQRQQSDH---DAERLREAIAE----LEREKEKLQQEAKLLQLKSEEMQTVQQE 2482
Query: 160 QIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE-TRAEFAERSVAKLEKTID 218
Q+ Q L+ +E+ + +++ E+ K ++L + E +A+ + ++ ++
Sbjct: 2483 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQME 2542
Query: 219 DLEERLYSQLERNRLLSNE 237
+RL + +E R +E
Sbjct: 2543 QERQRLVASMEEARRRQHE 2561
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 16/240 (6%)
Query: 11 KRKIQV-LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
KR IQ LQQ +E + R+ E R+R + E E+ + +++ E + A+
Sbjct: 1415 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1474
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
L + EEAE +++ + + + + ++ E++L EA R+ +
Sbjct: 1475 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1534
Query: 130 ARKLVIIEGDLERTEERAELAE-SRCREMDEQIRLMDQNLKC-----LSAAEEKYSQKED 183
+ L + E E R AE R R++ + ++ + ++ EK +Q E
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE-LKLTL 242
+EE + +EAE RA+ A+ E+ ++ E +LER +L +NE L+L L
Sbjct: 1595 SLQEEHVAVAQLREEAERRAQ----QQAEAERAREEAER----ELERWQLKANEALRLRL 1646
Score = 58.2 bits (139), Expect = 7e-09
Identities = 62/241 (25%), Positives = 119/241 (49%), Gaps = 31/241 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVE--GERRAR-EQAEAEVASLNRRIQLVEEELD 64
E +K ++ + + AEE A+R +++ E GE+ R E A E +L + +++ ++ D
Sbjct: 2383 ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2442
Query: 65 RAQERLATALQKLE-EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
ERL A+ +LE E EK E+ K+++ LK EE +Q+ QL + +++
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEA----KLLQ---LKSEEMQTVQQEQLLQETQALQQS- 2494
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
++ K +++ + +E+A+L EQ+ D+ K EE+ Q++
Sbjct: 2495 ----FLSEKDSLLQRERFIEQEKAKL---------EQL-FQDEVAKAQQLREEQQRQQQ- 2539
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ----LERNRLLSNELK 239
+ E+E + L ++EA R AE V + ++ + LE++ Q E N+ L +L+
Sbjct: 2540 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQ 2599
Query: 240 L 240
L
Sbjct: 2600 L 2600
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 23/227 (10%)
Query: 19 QQADDAEERAERLQREVEGERRAREQAEAEV------ASLNRRIQLVEEELDRAQERLAT 72
Q ++AE RA Q++ E E RARE+AE E+ A+ R++L EE+ + Q+ LA
Sbjct: 1605 QLREEAERRA---QQQAEAE-RAREEAERELERWQLKANEALRLRLQAEEVAQ-QKSLAQ 1659
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
A EAEK +E+ER + + + EL E +L++ + +AE ++ ++
Sbjct: 1660 A-----EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1714
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
L+ + + E+ E++ +L E + + Q + L A K + E E+ +L
Sbjct: 1715 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-----RAEMEV-LL 1768
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
K + E +E+S +LE E L + R R L+ E K
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAK 1814
Score = 54.7 bits (130), Expect = 7e-08
Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ +AEER ++ E R R+ A EV L +++ +RA++ A LQ
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2039
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVI 135
+EA + ++E + + E + LQ+ Q L + + AE A R EE V
Sbjct: 2040 QEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2099
Query: 136 IEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKEDKYEEEIKI 191
E + ++ + E AE + +EQ + Q K AE++ +++ + ++
Sbjct: 2100 AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2159
Query: 192 LTDKLKEAETRAEFAE---RSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
E E +FAE R A++E+ + L +L + LL EL+
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210
Score = 53.1 bits (126), Expect = 2e-07
Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 36/218 (16%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+QQ EE RLQRE + R++ EAE+A + ++++ RA+E
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE--------- 1776
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR---KYEEVARKLV 134
E+R+ ++ K L E + + +AEEA R EE R+
Sbjct: 1777 -----------------ESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKRQRQ 1818
Query: 135 IIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD 194
+ E D R AE R + E++ + + + + AE +KE + E ++ D
Sbjct: 1819 LAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Query: 195 KLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+ + E A + A +E+ + L + S+LER +
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1910
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 27/253 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ ++ +++ Q + +E +RL+ E R R Q E E+ S+ R+Q+ EEL +
Sbjct: 2188 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV--RVQM--EELSKL 2243
Query: 67 QERLATALQKL-------------EEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
+ R+ + L EEAEK +E + + A + +L E L
Sbjct: 2244 KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLA 2302
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
+ + +AE+ ++ + ++ ++ + E +++ ELA+ + R + E M Q L +
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2362
Query: 174 AEEKYSQKEDKYEEEIKILTDKLK----EAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++ + E + + E+ ++LK E AE + K +++ E+L+
Sbjct: 2363 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH---- 2418
Query: 230 RNRLLSNELKLTL 242
R L + E K+TL
Sbjct: 2419 RTELATQE-KVTL 2430
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/246 (20%), Positives = 116/246 (47%), Gaps = 22/246 (8%)
Query: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERR-------AREQAEAEVASLNRRIQL 58
T+ ++ + ++ +QQ + ER ++ +E +R+ A+ QAE E L +R+Q
Sbjct: 1340 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ- 1398
Query: 59 VEEELDRAQERLATA----------LQKLEEAEKAADESE-RGMKVIENRALKDEEKMEL 107
EE+ R +E A LQ+L ++ +A +++ R + E L+ EE++ +
Sbjct: 1399 --EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1456
Query: 108 QEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQN 167
+QL+ + A+ + + + + E + +E AE + ++ ++ R +
Sbjct: 1457 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1516
Query: 168 LKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAK-LEKTIDDLEERLYS 226
L AE + ++++ + + ++ L + +EAE R AE A+ ++ ++ + +
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
Query: 227 QLERNR 232
+L+ R
Sbjct: 1577 ELQSKR 1582
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/218 (25%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A+K + + E R++ E R++EQAE E A R+ QL EE R
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRR 1983
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAK---HIAEEAD 123
+E + L E+AA + + ++ +E K EE L+E +E+ +A+EA
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043
Query: 124 RK---YEEVARKLVI--IEGDLERTEERAELAESRCR-EMDEQIRLMDQNLKCLSAAEEK 177
+K EE A + E +L++T ++ + + R E + R ++ + AE +
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
+Q + EE ++ ++A+ RA+ A+ + KL K
Sbjct: 2104 AAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRK 2140
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/245 (21%), Positives = 107/245 (43%), Gaps = 16/245 (6%)
Query: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDR---- 65
K + ++ +E+ +RL+ E R E+A A R+ QL EE+ R
Sbjct: 1771 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1830
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIEN-----RALKDEEKMELQEIQLKEAKHIAE 120
A+ LA L + EA + E+E +K E R L ++E + + ++ + A+H A+
Sbjct: 1831 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1890
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+R +A+ + +LER + E + R+++E+I + + + +A + +
Sbjct: 1891 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL 1946
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + + ++AE A + A+ E+ + EER+ L + + K
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2006
Query: 241 TLHDL 245
L ++
Sbjct: 2007 ALEEV 2011
Score = 48.1 bits (113), Expect = 7e-06
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 33/222 (14%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQL-------VEEE 62
++ ++ L++ +D ER + L VE R R Q E E+ +L + +E E
Sbjct: 1891 IEERLAQLRKASDSELERQKGL---VEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1947
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
L R + L+ E+AE ++ R L EE+ +E + + K +A E
Sbjct: 1948 LGRIRSNAEDTLRSKEQAE---------LEAARQRQLAAEEERRRREAEERVQKSLAAE- 1997
Query: 123 DRKYEEVARKLVIIEGDLERTEERAE----LAESRCREMDEQIRLMDQNLKCLSAAEEK- 177
EE AR+ ++ER + + E L E +E Q++L + + AEEK
Sbjct: 1998 ----EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2053
Query: 178 ----YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
QKE + ++ ++ L + AE A R+ + E+
Sbjct: 2054 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/224 (23%), Positives = 100/224 (44%), Gaps = 28/224 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA-EAEVASLNRRIQLVEEELDRA 66
E + ++ Q LQQ ++ + +R +E E+ EQ + EVA + Q + EE R
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA----KAQQLREEQQRQ 2537
Query: 67 QERLATALQKL----EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Q+++ Q+L EEA + E+E G++ K EE +L++ + ++ + +AEE
Sbjct: 2538 QQQMEQERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEEN 2591
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
R E++ L + RA LA S Q+ A + ++ E
Sbjct: 2592 QRLREQL---------QLLEEQHRAALAHSE-EVTASQVAATKTLPNGRDALDGPAAEAE 2641
Query: 183 DKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
++ + K+ +L+EA + + +A+ T+D+L R
Sbjct: 2642 PEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARR 2685
Score = 41.2 bits (95), Expect = 8e-04
Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 57/285 (20%)
Query: 2 AGITTIEAVKRKIQVLQQQAD--------------DAEERAERLQREVEGERRAR-EQAE 46
A + +EA K ++ L+ QA+ A+E ERLQ+ GER E+
Sbjct: 1120 ATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQR-HGERDVEVERWR 1178
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-------------ESERGMKV 93
VA L R Q V + D Q L ++L ++AD E + M +
Sbjct: 1179 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1238
Query: 94 IENRALKDEEKME---LQEIQ-----LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 145
+++A++++ + E L+EI+ ++E + A++ ++ +LV + LE
Sbjct: 1239 ADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVAS 1298
Query: 146 RAEL------AESRCRE-------MDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
A+ +ES +E E L Q +K +S + ++E E++
Sbjct: 1299 PAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE 1358
Query: 193 TDKLKEAETR-------AEFAERSVAKLEKTIDDLEERLYSQLER 230
++L E E AE ++ A+ E+ +L++R+ ++ R
Sbjct: 1359 RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A++ + + + Q A+E AERL+R+V+ E + + QAE E+AS V+ E + A
Sbjct: 1443 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELAS------RVKAEAEAA 1496
Query: 67 QERLATALQKLEEAEKAADESERGMKVIE-------NRALKDEEKMELQEIQLKEAKHIA 119
+E+ ALQ LEE A+E+ER ++ E AL+ ++ E+Q K A
Sbjct: 1497 REK-QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1555
Query: 120 EEA--DRKYEEVARKLVIIEGDLE-RTEERAELAESR---CREMDEQIRLMDQNLKCLSA 173
+ A +R +E + + + E R +++AE +R RE++ ++ L+
Sbjct: 1556 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1615
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
AEE QK E K + +EA R + E++V + E +LE++
Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1665
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/242 (24%), Positives = 112/242 (46%), Gaps = 32/242 (13%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRARE-------QAEAEVASLNRRIQLVEE 61
AV++K Q LQQ + ++L+ E E RRA E QAE E A R+++ E
Sbjct: 2025 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2084
Query: 62 ELDRAQERLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHI 118
A+E+ Q AEK E+E+ E AL+ + + + ++++ K
Sbjct: 2085 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK---QAADAEMEKHKKF 2141
Query: 119 AEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKY 178
AE+ R+ +V ++L + LE T D Q L+D+ L+ L A +
Sbjct: 2142 AEQTLRQKAQVEQELTTLRLQLEET--------------DHQKNLLDEELQRLKAEATEA 2187
Query: 179 SQKEDKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLS 235
+++ + EEE +++ ++L + + R E R++ +K D+ + L + E+ + ++
Sbjct: 2188 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK--DNTQRFLQEEAEKMKQVA 2245
Query: 236 NE 237
E
Sbjct: 2246 EE 2247
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/259 (23%), Positives = 124/259 (47%), Gaps = 35/259 (13%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQR-----------EVEGERR---AREQAE 46
M + +K + ++LQQQ + A+E+A RLQ E +G +R A Q +
Sbjct: 2284 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2343
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 106
E+++ R++L E+ RAQ R E+A++ ++E + + L +EK+
Sbjct: 2344 LEMSAEAERLKLRVAEMSRAQARAE------EDAQRFRKQAEEIGEKLHRTELATQEKVT 2397
Query: 107 LQ---EIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREM----DE 159
L EIQ +++ H +A+R E +A +E + E+ ++ A+L + + EM E
Sbjct: 2398 LVQTLEIQRQQSDH---DAERLREAIAE----LEREKEKLQQEAKLLQLKSEEMQTVQQE 2450
Query: 160 QIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE-TRAEFAERSVAKLEKTID 218
Q+ Q L+ +E+ + +++ E+ K ++L + E +A+ + ++ ++
Sbjct: 2451 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQME 2510
Query: 219 DLEERLYSQLERNRLLSNE 237
+RL + +E R +E
Sbjct: 2511 QERQRLVASMEEARRRQHE 2529
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 16/240 (6%)
Query: 11 KRKIQV-LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
KR IQ LQQ +E + R+ E R+R + E E+ + +++ E + A+
Sbjct: 1383 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1442
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
L + EEAE +++ + + + + ++ E++L EA R+ +
Sbjct: 1443 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1502
Query: 130 ARKLVIIEGDLERTEERAELAE-SRCREMDEQIRLMDQNLKC-----LSAAEEKYSQKED 183
+ L + E E R AE R R++ + ++ + ++ EK +Q E
Sbjct: 1503 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1562
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE-LKLTL 242
+EE + +EAE RA+ A+ E+ ++ E +LER +L +NE L+L L
Sbjct: 1563 SLQEEHVAVAQLREEAERRAQ----QQAEAERAREEAER----ELERWQLKANEALRLRL 1614
Score = 58.2 bits (139), Expect = 7e-09
Identities = 62/241 (25%), Positives = 119/241 (49%), Gaps = 31/241 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVE--GERRAR-EQAEAEVASLNRRIQLVEEELD 64
E +K ++ + + AEE A+R +++ E GE+ R E A E +L + +++ ++ D
Sbjct: 2351 ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2410
Query: 65 RAQERLATALQKLE-EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
ERL A+ +LE E EK E+ K+++ LK EE +Q+ QL + +++
Sbjct: 2411 HDAERLREAIAELEREKEKLQQEA----KLLQ---LKSEEMQTVQQEQLLQETQALQQS- 2462
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
++ K +++ + +E+A+L EQ+ D+ K EE+ Q++
Sbjct: 2463 ----FLSEKDSLLQRERFIEQEKAKL---------EQL-FQDEVAKAQQLREEQQRQQQ- 2507
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ----LERNRLLSNELK 239
+ E+E + L ++EA R AE V + ++ + LE++ Q E N+ L +L+
Sbjct: 2508 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQ 2567
Query: 240 L 240
L
Sbjct: 2568 L 2568
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 23/227 (10%)
Query: 19 QQADDAEERAERLQREVEGERRAREQAEAEV------ASLNRRIQLVEEELDRAQERLAT 72
Q ++AE RA Q++ E E RARE+AE E+ A+ R++L EE+ + Q+ LA
Sbjct: 1573 QLREEAERRA---QQQAEAE-RAREEAERELERWQLKANEALRLRLQAEEVAQ-QKSLAQ 1627
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
A EAEK +E+ER + + + EL E +L++ + +AE ++ ++
Sbjct: 1628 A-----EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1682
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
L+ + + E+ E++ +L E + + Q + L A K + E E+ +L
Sbjct: 1683 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-----RAEMEV-LL 1736
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
K + E +E+S +LE E L + R R L+ E K
Sbjct: 1737 ASKARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAK 1782
Score = 54.7 bits (130), Expect = 7e-08
Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ +AEER ++ E R R+ A EV L +++ +RA++ A LQ
Sbjct: 1948 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2007
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVI 135
+EA + ++E + + E + LQ+ Q L + + AE A R EE V
Sbjct: 2008 QEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2067
Query: 136 IEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKEDKYEEEIKI 191
E + ++ + E AE + +EQ + Q K AE++ +++ + ++
Sbjct: 2068 AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2127
Query: 192 LTDKLKEAETRAEFAE---RSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
E E +FAE R A++E+ + L +L + LL EL+
Sbjct: 2128 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2178
Score = 53.1 bits (126), Expect = 2e-07
Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 36/218 (16%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+QQ EE RLQRE + R++ EAE+A + ++++ RA+E
Sbjct: 1694 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE--------- 1744
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR---KYEEVARKLV 134
E+R+ ++ K L E + + +AEEA R EE R+
Sbjct: 1745 -----------------ESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKRQRQ 1786
Query: 135 IIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD 194
+ E D R AE R + E++ + + + + AE +KE + E ++ D
Sbjct: 1787 LAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1840
Query: 195 KLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+ + E A + A +E+ + L + S+LER +
Sbjct: 1841 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1878
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 27/253 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ ++ +++ Q + +E +RL+ E R R Q E E+ S+ R+Q+ EEL +
Sbjct: 2156 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV--RVQM--EELSKL 2211
Query: 67 QERLATALQKL-------------EEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
+ R+ + L EEAEK +E + + A + +L E L
Sbjct: 2212 KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLA 2270
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
+ + +AE+ ++ + ++ ++ + E +++ ELA+ + R + E M Q L +
Sbjct: 2271 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2330
Query: 174 AEEKYSQKEDKYEEEIKILTDKLK----EAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++ + E + + E+ ++LK E AE + K +++ E+L+
Sbjct: 2331 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH---- 2386
Query: 230 RNRLLSNELKLTL 242
R L + E K+TL
Sbjct: 2387 RTELATQE-KVTL 2398
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/246 (20%), Positives = 116/246 (47%), Gaps = 22/246 (8%)
Query: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERR-------AREQAEAEVASLNRRIQL 58
T+ ++ + ++ +QQ + ER ++ +E +R+ A+ QAE E L +R+Q
Sbjct: 1308 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ- 1366
Query: 59 VEEELDRAQERLATA----------LQKLEEAEKAADESE-RGMKVIENRALKDEEKMEL 107
EE+ R +E A LQ+L ++ +A +++ R + E L+ EE++ +
Sbjct: 1367 --EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1424
Query: 108 QEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQN 167
+QL+ + A+ + + + + E + +E AE + ++ ++ R +
Sbjct: 1425 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1484
Query: 168 LKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAK-LEKTIDDLEERLYS 226
L AE + ++++ + + ++ L + +EAE R AE A+ ++ ++ + +
Sbjct: 1485 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1544
Query: 227 QLERNR 232
+L+ R
Sbjct: 1545 ELQSKR 1550
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/218 (25%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A+K + + E R++ E R++EQAE E A R+ QL EE R
Sbjct: 1895 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRR 1951
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAK---HIAEEAD 123
+E + L E+AA + + ++ +E K EE L+E +E+ +A+EA
Sbjct: 1952 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2011
Query: 124 RK---YEEVARKLVI--IEGDLERTEERAELAESRCR-EMDEQIRLMDQNLKCLSAAEEK 177
+K EE A + E +L++T ++ + + R E + R ++ + AE +
Sbjct: 2012 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2071
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
+Q + EE ++ ++A+ RA+ A+ + KL K
Sbjct: 2072 AAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRK 2108
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/245 (21%), Positives = 107/245 (43%), Gaps = 16/245 (6%)
Query: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDR---- 65
K + ++ +E+ +RL+ E R E+A A R+ QL EE+ R
Sbjct: 1739 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1798
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIEN-----RALKDEEKMELQEIQLKEAKHIAE 120
A+ LA L + EA + E+E +K E R L ++E + + ++ + A+H A+
Sbjct: 1799 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1858
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+R +A+ + +LER + E + R+++E+I + + + +A + +
Sbjct: 1859 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL 1914
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + + ++AE A + A+ E+ + EER+ L + + K
Sbjct: 1915 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 1974
Query: 241 TLHDL 245
L ++
Sbjct: 1975 ALEEV 1979
Score = 48.1 bits (113), Expect = 7e-06
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 33/222 (14%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQL-------VEEE 62
++ ++ L++ +D ER + L VE R R Q E E+ +L + +E E
Sbjct: 1859 IEERLAQLRKASDSELERQKGL---VEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1915
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
L R + L+ E+AE ++ R L EE+ +E + + K +A E
Sbjct: 1916 LGRIRSNAEDTLRSKEQAE---------LEAARQRQLAAEEERRRREAEERVQKSLAAE- 1965
Query: 123 DRKYEEVARKLVIIEGDLERTEERAE----LAESRCREMDEQIRLMDQNLKCLSAAEEK- 177
EE AR+ ++ER + + E L E +E Q++L + + AEEK
Sbjct: 1966 ----EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2021
Query: 178 ----YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
QKE + ++ ++ L + AE A R+ + E+
Sbjct: 2022 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2063
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/224 (23%), Positives = 100/224 (44%), Gaps = 28/224 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA-EAEVASLNRRIQLVEEELDRA 66
E + ++ Q LQQ ++ + +R +E E+ EQ + EVA + Q + EE R
Sbjct: 2450 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA----KAQQLREEQQRQ 2505
Query: 67 QERLATALQKL----EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Q+++ Q+L EEA + E+E G++ K EE +L++ + ++ + +AEE
Sbjct: 2506 QQQMEQERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEEN 2559
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
R E++ L + RA LA S Q+ A + ++ E
Sbjct: 2560 QRLREQL---------QLLEEQHRAALAHSE-EVTASQVAATKTLPNGRDALDGPAAEAE 2609
Query: 183 DKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
++ + K+ +L+EA + + +A+ T+D+L R
Sbjct: 2610 PEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARR 2653
Score = 41.2 bits (95), Expect = 8e-04
Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 57/285 (20%)
Query: 2 AGITTIEAVKRKIQVLQQQAD--------------DAEERAERLQREVEGERRAR-EQAE 46
A + +EA K ++ L+ QA+ A+E ERLQ+ GER E+
Sbjct: 1088 ATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQR-HGERDVEVERWR 1146
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-------------ESERGMKV 93
VA L R Q V + D Q L ++L ++AD E + M +
Sbjct: 1147 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1206
Query: 94 IENRALKDEEKME---LQEIQ-----LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 145
+++A++++ + E L+EI+ ++E + A++ ++ +LV + LE
Sbjct: 1207 ADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVAS 1266
Query: 146 RAEL------AESRCRE-------MDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
A+ +ES +E E L Q +K +S + ++E E++
Sbjct: 1267 PAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE 1326
Query: 193 TDKLKEAETR-------AEFAERSVAKLEKTIDDLEERLYSQLER 230
++L E E AE ++ A+ E+ +L++R+ ++ R
Sbjct: 1327 RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1371
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A++ + + + Q A+E AERL+R+V+ E + + QAE E+AS V+ E + A
Sbjct: 1612 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELAS------RVKAEAEAA 1665
Query: 67 QERLATALQKLEEAEKAADESERGMKVIE-------NRALKDEEKMELQEIQLKEAKHIA 119
+E+ ALQ LEE A+E+ER ++ E AL+ ++ E+Q K A
Sbjct: 1666 REK-QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1724
Query: 120 EEA--DRKYEEVARKLVIIEGDLE-RTEERAELAESR---CREMDEQIRLMDQNLKCLSA 173
+ A +R +E + + + E R +++AE +R RE++ ++ L+
Sbjct: 1725 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1784
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
AEE QK E K + +EA R + E++V + E +LE++
Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1834
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/242 (24%), Positives = 112/242 (46%), Gaps = 32/242 (13%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRARE-------QAEAEVASLNRRIQLVEE 61
AV++K Q LQQ + ++L+ E E RRA E QAE E A R+++ E
Sbjct: 2194 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2253
Query: 62 ELDRAQERLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHI 118
A+E+ Q AEK E+E+ E AL+ + + + ++++ K
Sbjct: 2254 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK---QAADAEMEKHKKF 2310
Query: 119 AEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKY 178
AE+ R+ +V ++L + LE T D Q L+D+ L+ L A +
Sbjct: 2311 AEQTLRQKAQVEQELTTLRLQLEET--------------DHQKNLLDEELQRLKAEATEA 2356
Query: 179 SQKEDKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLS 235
+++ + EEE +++ ++L + + R E R++ +K D+ + L + E+ + ++
Sbjct: 2357 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK--DNTQRFLQEEAEKMKQVA 2414
Query: 236 NE 237
E
Sbjct: 2415 EE 2416
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/259 (23%), Positives = 124/259 (47%), Gaps = 35/259 (13%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQR-----------EVEGERR---AREQAE 46
M + +K + ++LQQQ + A+E+A RLQ E +G +R A Q +
Sbjct: 2453 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2512
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 106
E+++ R++L E+ RAQ R E+A++ ++E + + L +EK+
Sbjct: 2513 LEMSAEAERLKLRVAEMSRAQARAE------EDAQRFRKQAEEIGEKLHRTELATQEKVT 2566
Query: 107 LQ---EIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREM----DE 159
L EIQ +++ H +A+R E +A +E + E+ ++ A+L + + EM E
Sbjct: 2567 LVQTLEIQRQQSDH---DAERLREAIAE----LEREKEKLQQEAKLLQLKSEEMQTVQQE 2619
Query: 160 QIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE-TRAEFAERSVAKLEKTID 218
Q+ Q L+ +E+ + +++ E+ K ++L + E +A+ + ++ ++
Sbjct: 2620 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQME 2679
Query: 219 DLEERLYSQLERNRLLSNE 237
+RL + +E R +E
Sbjct: 2680 QERQRLVASMEEARRRQHE 2698
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 16/240 (6%)
Query: 11 KRKIQV-LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
KR IQ LQQ +E + R+ E R+R + E E+ + +++ E + A+
Sbjct: 1552 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1611
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
L + EEAE +++ + + + + ++ E++L EA R+ +
Sbjct: 1612 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1671
Query: 130 ARKLVIIEGDLERTEERAELAE-SRCREMDEQIRLMDQNLKC-----LSAAEEKYSQKED 183
+ L + E E R AE R R++ + ++ + ++ EK +Q E
Sbjct: 1672 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1731
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE-LKLTL 242
+EE + +EAE RA+ A+ E+ ++ E +LER +L +NE L+L L
Sbjct: 1732 SLQEEHVAVAQLREEAERRAQ----QQAEAERAREEAER----ELERWQLKANEALRLRL 1783
Score = 58.2 bits (139), Expect = 7e-09
Identities = 62/241 (25%), Positives = 119/241 (49%), Gaps = 31/241 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVE--GERRAR-EQAEAEVASLNRRIQLVEEELD 64
E +K ++ + + AEE A+R +++ E GE+ R E A E +L + +++ ++ D
Sbjct: 2520 ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2579
Query: 65 RAQERLATALQKLE-EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
ERL A+ +LE E EK E+ K+++ LK EE +Q+ QL + +++
Sbjct: 2580 HDAERLREAIAELEREKEKLQQEA----KLLQ---LKSEEMQTVQQEQLLQETQALQQS- 2631
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
++ K +++ + +E+A+L EQ+ D+ K EE+ Q++
Sbjct: 2632 ----FLSEKDSLLQRERFIEQEKAKL---------EQL-FQDEVAKAQQLREEQQRQQQ- 2676
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ----LERNRLLSNELK 239
+ E+E + L ++EA R AE V + ++ + LE++ Q E N+ L +L+
Sbjct: 2677 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQ 2736
Query: 240 L 240
L
Sbjct: 2737 L 2737
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 23/227 (10%)
Query: 19 QQADDAEERAERLQREVEGERRAREQAEAEV------ASLNRRIQLVEEELDRAQERLAT 72
Q ++AE RA Q++ E E RARE+AE E+ A+ R++L EE+ + Q+ LA
Sbjct: 1742 QLREEAERRA---QQQAEAE-RAREEAERELERWQLKANEALRLRLQAEEVAQ-QKSLAQ 1796
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
A EAEK +E+ER + + + EL E +L++ + +AE ++ ++
Sbjct: 1797 A-----EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1851
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
L+ + + E+ E++ +L E + + Q + L A K + E E+ +L
Sbjct: 1852 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-----RAEMEV-LL 1905
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
K + E +E+S +LE E L + R R L+ E K
Sbjct: 1906 ASKARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAK 1951
Score = 54.7 bits (130), Expect = 7e-08
Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ +AEER ++ E R R+ A EV L +++ +RA++ A LQ
Sbjct: 2117 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2176
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVI 135
+EA + ++E + + E + LQ+ Q L + + AE A R EE V
Sbjct: 2177 QEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2236
Query: 136 IEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKEDKYEEEIKI 191
E + ++ + E AE + +EQ + Q K AE++ +++ + ++
Sbjct: 2237 AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2296
Query: 192 LTDKLKEAETRAEFAE---RSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
E E +FAE R A++E+ + L +L + LL EL+
Sbjct: 2297 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2347
Score = 53.1 bits (126), Expect = 2e-07
Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 36/218 (16%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+QQ EE RLQRE + R++ EAE+A + ++++ RA+E
Sbjct: 1863 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE--------- 1913
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR---KYEEVARKLV 134
E+R+ ++ K L E + + +AEEA R EE R+
Sbjct: 1914 -----------------ESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKRQRQ 1955
Query: 135 IIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD 194
+ E D R AE R + E++ + + + + AE +KE + E ++ D
Sbjct: 1956 LAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 2009
Query: 195 KLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+ + E A + A +E+ + L + S+LER +
Sbjct: 2010 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 2047
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 27/253 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ ++ +++ Q + +E +RL+ E R R Q E E+ S+ R+Q+ EEL +
Sbjct: 2325 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV--RVQM--EELSKL 2380
Query: 67 QERLATALQKL-------------EEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
+ R+ + L EEAEK +E + + A + +L E L
Sbjct: 2381 KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLA 2439
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
+ + +AE+ ++ + ++ ++ + E +++ ELA+ + R + E M Q L +
Sbjct: 2440 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2499
Query: 174 AEEKYSQKEDKYEEEIKILTDKLK----EAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++ + E + + E+ ++LK E AE + K +++ E+L+
Sbjct: 2500 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH---- 2555
Query: 230 RNRLLSNELKLTL 242
R L + E K+TL
Sbjct: 2556 RTELATQE-KVTL 2567
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/246 (20%), Positives = 116/246 (47%), Gaps = 22/246 (8%)
Query: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERR-------AREQAEAEVASLNRRIQL 58
T+ ++ + ++ +QQ + ER ++ +E +R+ A+ QAE E L +R+Q
Sbjct: 1477 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ- 1535
Query: 59 VEEELDRAQERLATA----------LQKLEEAEKAADESE-RGMKVIENRALKDEEKMEL 107
EE+ R +E A LQ+L ++ +A +++ R + E L+ EE++ +
Sbjct: 1536 --EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1593
Query: 108 QEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQN 167
+QL+ + A+ + + + + E + +E AE + ++ ++ R +
Sbjct: 1594 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1653
Query: 168 LKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAK-LEKTIDDLEERLYS 226
L AE + ++++ + + ++ L + +EAE R AE A+ ++ ++ + +
Sbjct: 1654 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1713
Query: 227 QLERNR 232
+L+ R
Sbjct: 1714 ELQSKR 1719
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/218 (25%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A+K + + E R++ E R++EQAE E A R+ QL EE R
Sbjct: 2064 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRR 2120
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAK---HIAEEAD 123
+E + L E+AA + + ++ +E K EE L+E +E+ +A+EA
Sbjct: 2121 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2180
Query: 124 RK---YEEVARKLVI--IEGDLERTEERAELAESRCR-EMDEQIRLMDQNLKCLSAAEEK 177
+K EE A + E +L++T ++ + + R E + R ++ + AE +
Sbjct: 2181 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2240
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
+Q + EE ++ ++A+ RA+ A+ + KL K
Sbjct: 2241 AAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRK 2277
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/245 (21%), Positives = 107/245 (43%), Gaps = 16/245 (6%)
Query: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDR---- 65
K + ++ +E+ +RL+ E R E+A A R+ QL EE+ R
Sbjct: 1908 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1967
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIEN-----RALKDEEKMELQEIQLKEAKHIAE 120
A+ LA L + EA + E+E +K E R L ++E + + ++ + A+H A+
Sbjct: 1968 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 2027
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+R +A+ + +LER + E + R+++E+I + + + +A + +
Sbjct: 2028 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL 2083
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + + ++AE A + A+ E+ + EER+ L + + K
Sbjct: 2084 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2143
Query: 241 TLHDL 245
L ++
Sbjct: 2144 ALEEV 2148
Score = 48.1 bits (113), Expect = 7e-06
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 33/222 (14%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQL-------VEEE 62
++ ++ L++ +D ER + L VE R R Q E E+ +L + +E E
Sbjct: 2028 IEERLAQLRKASDSELERQKGL---VEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 2084
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
L R + L+ E+AE ++ R L EE+ +E + + K +A E
Sbjct: 2085 LGRIRSNAEDTLRSKEQAE---------LEAARQRQLAAEEERRRREAEERVQKSLAAE- 2134
Query: 123 DRKYEEVARKLVIIEGDLERTEERAE----LAESRCREMDEQIRLMDQNLKCLSAAEEK- 177
EE AR+ ++ER + + E L E +E Q++L + + AEEK
Sbjct: 2135 ----EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2190
Query: 178 ----YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
QKE + ++ ++ L + AE A R+ + E+
Sbjct: 2191 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2232
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/224 (23%), Positives = 100/224 (44%), Gaps = 28/224 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA-EAEVASLNRRIQLVEEELDRA 66
E + ++ Q LQQ ++ + +R +E E+ EQ + EVA + Q + EE R
Sbjct: 2619 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA----KAQQLREEQQRQ 2674
Query: 67 QERLATALQKL----EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Q+++ Q+L EEA + E+E G++ K EE +L++ + ++ + +AEE
Sbjct: 2675 QQQMEQERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEEN 2728
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
R E++ L + RA LA S Q+ A + ++ E
Sbjct: 2729 QRLREQL---------QLLEEQHRAALAHSE-EVTASQVAATKTLPNGRDALDGPAAEAE 2778
Query: 183 DKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
++ + K+ +L+EA + + +A+ T+D+L R
Sbjct: 2779 PEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARR 2822
Score = 41.2 bits (95), Expect = 8e-04
Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 57/285 (20%)
Query: 2 AGITTIEAVKRKIQVLQQQAD--------------DAEERAERLQREVEGERRAR-EQAE 46
A + +EA K ++ L+ QA+ A+E ERLQ+ GER E+
Sbjct: 1257 ATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQR-HGERDVEVERWR 1315
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-------------ESERGMKV 93
VA L R Q V + D Q L ++L ++AD E + M +
Sbjct: 1316 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1375
Query: 94 IENRALKDEEKME---LQEIQ-----LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 145
+++A++++ + E L+EI+ ++E + A++ ++ +LV + LE
Sbjct: 1376 ADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVAS 1435
Query: 146 RAEL------AESRCRE-------MDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
A+ +ES +E E L Q +K +S + ++E E++
Sbjct: 1436 PAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE 1495
Query: 193 TDKLKEAETR-------AEFAERSVAKLEKTIDDLEERLYSQLER 230
++L E E AE ++ A+ E+ +L++R+ ++ R
Sbjct: 1496 RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1540
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 20/230 (8%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
++A++ + + + Q A+E AERL+R+V+ E + + QAE E+AS V+ E + A
Sbjct: 1453 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELAS------RVKAEAEAA 1506
Query: 67 QERLATALQKLEEAEKAADESERGMKVIE-------NRALKDEEKMELQEIQLKEAKHIA 119
+E+ ALQ LEE A+E+ER ++ E AL+ ++ E+Q K A
Sbjct: 1507 REK-QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1565
Query: 120 EEA--DRKYEEVARKLVIIEGDLE-RTEERAELAESR---CREMDEQIRLMDQNLKCLSA 173
+ A +R +E + + + E R +++AE +R RE++ ++ L+
Sbjct: 1566 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1625
Query: 174 AEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
AEE QK E K + +EA R + E++V + E +LE++
Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1675
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/242 (24%), Positives = 112/242 (46%), Gaps = 32/242 (13%)
Query: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRARE-------QAEAEVASLNRRIQLVEE 61
AV++K Q LQQ + ++L+ E E RRA E QAE E A R+++ E
Sbjct: 2035 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2094
Query: 62 ELDRAQERLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHI 118
A+E+ Q AEK E+E+ E AL+ + + + ++++ K
Sbjct: 2095 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK---QAADAEMEKHKKF 2151
Query: 119 AEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKY 178
AE+ R+ +V ++L + LE T D Q L+D+ L+ L A +
Sbjct: 2152 AEQTLRQKAQVEQELTTLRLQLEET--------------DHQKNLLDEELQRLKAEATEA 2197
Query: 179 SQKEDKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLS 235
+++ + EEE +++ ++L + + R E R++ +K D+ + L + E+ + ++
Sbjct: 2198 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK--DNTQRFLQEEAEKMKQVA 2255
Query: 236 NE 237
E
Sbjct: 2256 EE 2257
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/259 (23%), Positives = 124/259 (47%), Gaps = 35/259 (13%)
Query: 1 MAGITTIEAVKRKIQVLQQQADDAEERAERLQR-----------EVEGERR---AREQAE 46
M + +K + ++LQQQ + A+E+A RLQ E +G +R A Q +
Sbjct: 2294 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2353
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 106
E+++ R++L E+ RAQ R E+A++ ++E + + L +EK+
Sbjct: 2354 LEMSAEAERLKLRVAEMSRAQARAE------EDAQRFRKQAEEIGEKLHRTELATQEKVT 2407
Query: 107 LQ---EIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREM----DE 159
L EIQ +++ H +A+R E +A +E + E+ ++ A+L + + EM E
Sbjct: 2408 LVQTLEIQRQQSDH---DAERLREAIAE----LEREKEKLQQEAKLLQLKSEEMQTVQQE 2460
Query: 160 QIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE-TRAEFAERSVAKLEKTID 218
Q+ Q L+ +E+ + +++ E+ K ++L + E +A+ + ++ ++
Sbjct: 2461 QLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQME 2520
Query: 219 DLEERLYSQLERNRLLSNE 237
+RL + +E R +E
Sbjct: 2521 QERQRLVASMEEARRRQHE 2539
Score = 58.9 bits (141), Expect = 4e-09
Identities = 57/240 (23%), Positives = 106/240 (44%), Gaps = 16/240 (6%)
Query: 11 KRKIQV-LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQER 69
KR IQ LQQ +E + R+ E R+R + E E+ + +++ E + A+
Sbjct: 1393 KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGE 1452
Query: 70 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEV 129
L + EEAE +++ + + + + ++ E++L EA R+ +
Sbjct: 1453 LQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA 1512
Query: 130 ARKLVIIEGDLERTEERAELAE-SRCREMDEQIRLMDQNLKC-----LSAAEEKYSQKED 183
+ L + E E R AE R R++ + ++ + ++ EK +Q E
Sbjct: 1513 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1572
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNE-LKLTL 242
+EE + +EAE RA+ A+ E+ ++ E +LER +L +NE L+L L
Sbjct: 1573 SLQEEHVAVAQLREEAERRAQ----QQAEAERAREEAER----ELERWQLKANEALRLRL 1624
Score = 58.2 bits (139), Expect = 7e-09
Identities = 62/241 (25%), Positives = 119/241 (49%), Gaps = 31/241 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVE--GERRAR-EQAEAEVASLNRRIQLVEEELD 64
E +K ++ + + AEE A+R +++ E GE+ R E A E +L + +++ ++ D
Sbjct: 2361 ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2420
Query: 65 RAQERLATALQKLE-EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
ERL A+ +LE E EK E+ K+++ LK EE +Q+ QL + +++
Sbjct: 2421 HDAERLREAIAELEREKEKLQQEA----KLLQ---LKSEEMQTVQQEQLLQETQALQQS- 2472
Query: 124 RKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKED 183
++ K +++ + +E+A+L EQ+ D+ K EE+ Q++
Sbjct: 2473 ----FLSEKDSLLQRERFIEQEKAKL---------EQL-FQDEVAKAQQLREEQQRQQQ- 2517
Query: 184 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQ----LERNRLLSNELK 239
+ E+E + L ++EA R AE V + ++ + LE++ Q E N+ L +L+
Sbjct: 2518 QMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQ 2577
Query: 240 L 240
L
Sbjct: 2578 L 2578
Score = 56.2 bits (134), Expect = 3e-08
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 23/227 (10%)
Query: 19 QQADDAEERAERLQREVEGERRAREQAEAEV------ASLNRRIQLVEEELDRAQERLAT 72
Q ++AE RA Q++ E E RARE+AE E+ A+ R++L EE+ + Q+ LA
Sbjct: 1583 QLREEAERRA---QQQAEAE-RAREEAERELERWQLKANEALRLRLQAEEVAQ-QKSLAQ 1637
Query: 73 ALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 132
A EAEK +E+ER + + + EL E +L++ + +AE ++ ++
Sbjct: 1638 A-----EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1692
Query: 133 LVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
L+ + + E+ E++ +L E + + Q + L A K + E E+ +L
Sbjct: 1693 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-----RAEMEV-LL 1746
Query: 193 TDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
K + E +E+S +LE E L + R R L+ E K
Sbjct: 1747 ASKARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAK 1792
Score = 54.7 bits (130), Expect = 7e-08
Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 9/231 (3%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+++ +AEER ++ E R R+ A EV L +++ +RA++ A LQ
Sbjct: 1958 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2017
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVI 135
+EA + ++E + + E + LQ+ Q L + + AE A R EE V
Sbjct: 2018 QEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2077
Query: 136 IEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKEDKYEEEIKI 191
E + ++ + E AE + +EQ + Q K AE++ +++ + ++
Sbjct: 2078 AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2137
Query: 192 LTDKLKEAETRAEFAE---RSVAKLEKTIDDLEERLYSQLERNRLLSNELK 239
E E +FAE R A++E+ + L +L + LL EL+
Sbjct: 2138 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2188
Score = 53.1 bits (126), Expect = 2e-07
Identities = 52/218 (23%), Positives = 92/218 (42%), Gaps = 36/218 (16%)
Query: 18 QQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKL 77
+QQ EE RLQRE + R++ EAE+A + ++++ RA+E
Sbjct: 1704 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEE--------- 1754
Query: 78 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR---KYEEVARKLV 134
E+R+ ++ K L E + + +AEEA R EE R+
Sbjct: 1755 -----------------ESRSTSEKSKQRL-EAEAGRFRELAEEAARLRALAEEAKRQRQ 1796
Query: 135 IIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTD 194
+ E D R AE R + E++ + + + + AE +KE + E ++ D
Sbjct: 1797 LAEEDAARQRAEAE------RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1850
Query: 195 KLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNR 232
+ + E A + A +E+ + L + S+LER +
Sbjct: 1851 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1888
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 27/253 (10%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
+ ++ +++ Q + +E +RL+ E R R Q E E+ S+ R+Q+ EEL +
Sbjct: 2166 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV--RVQM--EELSKL 2221
Query: 67 QERLATALQKL-------------EEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 113
+ R+ + L EEAEK +E + + A + +L E L
Sbjct: 2222 KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQEAARLRQLAEEDLA 2280
Query: 114 EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSA 173
+ + +AE+ ++ + ++ ++ + E +++ ELA+ + R + E M Q L +
Sbjct: 2281 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2340
Query: 174 AEEKYSQKEDKYEEEIKILTDKLK----EAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
++ + E + + E+ ++LK E AE + K +++ E+L+
Sbjct: 2341 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH---- 2396
Query: 230 RNRLLSNELKLTL 242
R L + E K+TL
Sbjct: 2397 RTELATQE-KVTL 2408
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/246 (20%), Positives = 116/246 (47%), Gaps = 22/246 (8%)
Query: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERR-------AREQAEAEVASLNRRIQL 58
T+ ++ + ++ +QQ + ER ++ +E +R+ A+ QAE E L +R+Q
Sbjct: 1318 TLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ- 1376
Query: 59 VEEELDRAQERLATA----------LQKLEEAEKAADESE-RGMKVIENRALKDEEKMEL 107
EE+ R +E A LQ+L ++ +A +++ R + E L+ EE++ +
Sbjct: 1377 --EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1434
Query: 108 QEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQN 167
+QL+ + A+ + + + + E + +E AE + ++ ++ R +
Sbjct: 1435 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1494
Query: 168 LKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAK-LEKTIDDLEERLYS 226
L AE + ++++ + + ++ L + +EAE R AE A+ ++ ++ + +
Sbjct: 1495 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1554
Query: 227 QLERNR 232
+L+ R
Sbjct: 1555 ELQSKR 1560
Score = 52.4 bits (124), Expect = 4e-07
Identities = 56/218 (25%), Positives = 101/218 (46%), Gaps = 13/218 (5%)
Query: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
I A+K + + E R++ E R++EQAE E A R+ QL EE R
Sbjct: 1905 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRR 1961
Query: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAK---HIAEEAD 123
+E + L E+AA + + ++ +E K EE L+E +E+ +A+EA
Sbjct: 1962 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2021
Query: 124 RK---YEEVARKLVI--IEGDLERTEERAELAESRCR-EMDEQIRLMDQNLKCLSAAEEK 177
+K EE A + E +L++T ++ + + R E + R ++ + AE +
Sbjct: 2022 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2081
Query: 178 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
+Q + EE ++ ++A+ RA+ A+ + KL K
Sbjct: 2082 AAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRK 2118
Score = 49.7 bits (117), Expect = 2e-06
Identities = 52/245 (21%), Positives = 107/245 (43%), Gaps = 16/245 (6%)
Query: 13 KIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEEELDR---- 65
K + ++ +E+ +RL+ E R E+A A R+ QL EE+ R
Sbjct: 1749 KARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1808
Query: 66 AQERLATALQKLEEAEKAADESERGMKVIEN-----RALKDEEKMELQEIQLKEAKHIAE 120
A+ LA L + EA + E+E +K E R L ++E + + ++ + A+H A+
Sbjct: 1809 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1868
Query: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ 180
+R +A+ + +LER + E + R+++E+I + + + +A + +
Sbjct: 1869 IEER----LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELEL 1924
Query: 181 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKL 240
+ + + ++AE A + A+ E+ + EER+ L + + K
Sbjct: 1925 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 1984
Query: 241 TLHDL 245
L ++
Sbjct: 1985 ALEEV 1989
Score = 48.1 bits (113), Expect = 7e-06
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 33/222 (14%)
Query: 10 VKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQL-------VEEE 62
++ ++ L++ +D ER + L VE R R Q E E+ +L + +E E
Sbjct: 1869 IEERLAQLRKASDSELERQKGL---VEDTLRQRRQVEEEILALKASFEKAAAGKAELELE 1925
Query: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
L R + L+ E+AE ++ R L EE+ +E + + K +A E
Sbjct: 1926 LGRIRSNAEDTLRSKEQAE---------LEAARQRQLAAEEERRRREAEERVQKSLAAE- 1975
Query: 123 DRKYEEVARKLVIIEGDLERTEERAE----LAESRCREMDEQIRLMDQNLKCLSAAEEK- 177
EE AR+ ++ER + + E L E +E Q++L + + AEEK
Sbjct: 1976 ----EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2031
Query: 178 ----YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
QKE + ++ ++ L + AE A R+ + E+
Sbjct: 2032 HAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2073
Score = 42.4 bits (98), Expect = 4e-04
Identities = 53/224 (23%), Positives = 100/224 (44%), Gaps = 28/224 (12%)
Query: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA-EAEVASLNRRIQLVEEELDRA 66
E + ++ Q LQQ ++ + +R +E E+ EQ + EVA + Q + EE R
Sbjct: 2460 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA----KAQQLREEQQRQ 2515
Query: 67 QERLATALQKL----EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Q+++ Q+L EEA + E+E G++ K EE +L++ + ++ + +AEE
Sbjct: 2516 QQQMEQERQRLVASMEEARRRQHEAEEGVR------RKQEELQQLEQQRRQQEELLAEEN 2569
Query: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
R E++ L + RA LA S Q+ A + ++ E
Sbjct: 2570 QRLREQL---------QLLEEQHRAALAHSE-EVTASQVAATKTLPNGRDALDGPAAEAE 2619
Query: 183 DKYEEE---IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
++ + K+ +L+EA + + +A+ T+D+L R
Sbjct: 2620 PEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARR 2663
Score = 41.2 bits (95), Expect = 8e-04
Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 57/285 (20%)
Query: 2 AGITTIEAVKRKIQVLQQQAD--------------DAEERAERLQREVEGERRAR-EQAE 46
A + +EA K ++ L+ QA+ A+E ERLQ+ GER E+
Sbjct: 1098 ATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQR-HGERDVEVERWR 1156
Query: 47 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD-------------ESERGMKV 93
VA L R Q V + D Q L ++L ++AD E + M +
Sbjct: 1157 ERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1216
Query: 94 IENRALKDEEKME---LQEIQ-----LKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 145
+++A++++ + E L+EI+ ++E + A++ ++ +LV + LE
Sbjct: 1217 ADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVAS 1276
Query: 146 RAEL------AESRCRE-------MDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIL 192
A+ +ES +E E L Q +K +S + ++E E++
Sbjct: 1277 PAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE 1336
Query: 193 TDKLKEAETR-------AEFAERSVAKLEKTIDDLEERLYSQLER 230
++L E E AE ++ A+ E+ +L++R+ ++ R
Sbjct: 1337 RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.312
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,349,631
Number of Sequences: 37866
Number of extensions: 326071
Number of successful extensions: 12877
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 700
Number of HSP's successfully gapped in prelim test: 921
Number of HSP's that attempted gapping in prelim test: 3269
Number of HSP's gapped (non-prelim): 5685
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.