BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21956641 ISL LIM homeobox 2 [Homo sapiens] (359 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 740 0.0 gi|115387114 islet-1 [Homo sapiens] 551 e-157 gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 181 7e-46 gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 181 7e-46 gi|30795196 LIM homeobox protein 2 [Homo sapiens] 177 1e-44 gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 177 2e-44 gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 175 6e-44 gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 164 1e-40 gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 164 1e-40 gi|30410785 LIM homeobox protein 1 [Homo sapiens] 164 1e-40 gi|11641283 LIM homeobox protein 5 [Homo sapiens] 161 7e-40 gi|15375314 LIM homeobox protein 4 [Homo sapiens] 160 2e-39 gi|50083287 LIM homeobox 8 [Homo sapiens] 159 5e-39 gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 158 8e-39 gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 158 8e-39 gi|5803072 LIM domain only 4 [Homo sapiens] 112 4e-25 gi|21361802 LIM domain only 3 [Homo sapiens] 107 2e-23 gi|47778935 LIM domain only 3 [Homo sapiens] 107 2e-23 gi|4505005 LIM domain only 1 [Homo sapiens] 105 5e-23 gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 92 5e-19 gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 92 5e-19 gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 92 5e-19 gi|4505001 LIM domain kinase 1 [Homo sapiens] 81 1e-15 gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 81 2e-15 gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 81 2e-15 gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 81 2e-15 gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 75 9e-14 gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens] 72 6e-13 gi|194272207 actin binding LIM protein family, member 2 isoform ... 71 1e-12 gi|153792514 actin binding LIM protein family, member 2 isoform ... 71 1e-12 >gi|21956641 ISL LIM homeobox 2 [Homo sapiens] Length = 359 Score = 740 bits (1911), Expect = 0.0 Identities = 359/359 (100%), Positives = 359/359 (100%) Query: 1 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ 60 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ Sbjct: 1 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ 60 Query: 61 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC 120 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC Sbjct: 61 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC 120 Query: 121 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL 180 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL Sbjct: 121 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL 180 Query: 181 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ 240 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ Sbjct: 181 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ 240 Query: 241 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP 300 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP Sbjct: 241 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP 300 Query: 301 WKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET 359 WKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET Sbjct: 301 WKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET 359 >gi|115387114 islet-1 [Homo sapiens] Length = 349 Score = 551 bits (1421), Expect = e-157 Identities = 264/349 (75%), Positives = 301/349 (86%), Gaps = 2/349 (0%) Query: 11 LGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFV 70 +G MGD KKK ++CVGCG+QIHDQ+ILRVSPDLEWHAACLKCAEC+QYLDE+CTCFV Sbjct: 1 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFV 60 Query: 71 RDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEF 130 RDGKTYCKRDY+RL+GIKCAKC +GFS +D VMRAR VYHIECFRC CSRQL+PGDEF Sbjct: 61 RDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEF 120 Query: 131 SLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP-DAGSGRQPALRPHVHKQTE 189 +LRE L CRADH ++ ERA+ G+ PL AR L + + S RQPALRPHVHKQ E Sbjct: 121 ALREDGLFCRADHDVV-ERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPE 179 Query: 190 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKK 249 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK+ Sbjct: 180 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR 239 Query: 250 SILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFAL 309 SI+MKQLQQQQ +DKT++QG+TGTP+VA SP RH+ +Q + VEVQ+YQPPWK LS+FAL Sbjct: 240 SIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFAL 299 Query: 310 QSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVE 358 QSD+DQPAFQQLV+FSE G NS+GS+V S+SSQLPDTPNSMV SP+E Sbjct: 300 QSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIE 348 >gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] Length = 397 Score = 181 bits (460), Expect = 7e-46 Identities = 104/283 (36%), Positives = 155/283 (54%), Gaps = 37/283 (13%) Query: 18 SKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYC 77 S +KP A+C GCG +I D++ L ++ D +WH CLKC EC L+ TCF +DG YC Sbjct: 64 SPEKP--ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC 120 Query: 78 KRDYVRLFGI-KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHE 136 K DY R F + +CA+C +G S+S++VMRARDSVYH+ CF CS C++ L GD F +++ Sbjct: 121 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL 180 Query: 137 LLCRADHGLLLE------------RAAAGSPRSP-----GPLPGAR---------GLHLP 170 + CRA LL+ A +G P G + R G+ + Sbjct: 181 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV 240 Query: 171 DAGSGRQPALRPHVHKQ------TEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQL 224 + SG H+ + ++KT R+RT QL T+++ +A N PDA +QL Sbjct: 241 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL 300 Query: 225 VEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSL 267 + TGL+ RV++VWFQN R K ++++L ++ +D TSL Sbjct: 301 AQKTGLTKRVLQVWFQNARAK-FRRNLLRQENGGVDKADGTSL 342 >gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] Length = 388 Score = 181 bits (460), Expect = 7e-46 Identities = 104/283 (36%), Positives = 155/283 (54%), Gaps = 37/283 (13%) Query: 18 SKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYC 77 S +KP A+C GCG +I D++ L ++ D +WH CLKC EC L+ TCF +DG YC Sbjct: 55 SPEKP--ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC 111 Query: 78 KRDYVRLFGI-KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHE 136 K DY R F + +CA+C +G S+S++VMRARDSVYH+ CF CS C++ L GD F +++ Sbjct: 112 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL 171 Query: 137 LLCRADHGLLLE------------RAAAGSPRSP-----GPLPGAR---------GLHLP 170 + CRA LL+ A +G P G + R G+ + Sbjct: 172 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV 231 Query: 171 DAGSGRQPALRPHVHKQ------TEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQL 224 + SG H+ + ++KT R+RT QL T+++ +A N PDA +QL Sbjct: 232 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL 291 Query: 225 VEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSL 267 + TGL+ RV++VWFQN R K ++++L ++ +D TSL Sbjct: 292 AQKTGLTKRVLQVWFQNARAK-FRRNLLRQENGGVDKADGTSL 333 >gi|30795196 LIM homeobox protein 2 [Homo sapiens] Length = 406 Score = 177 bits (449), Expect = 1e-44 Identities = 106/300 (35%), Positives = 153/300 (51%), Gaps = 54/300 (18%) Query: 25 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRL 84 A+C GCG +I D++ L ++ D +WH CLKC EC L+ TCF +DG YCK DY R Sbjct: 51 ALCAGCGGKISDRYYL-LAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRR 109 Query: 85 FGI-KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADH 143 F + +CA+C +G S+S++VMRARD VYH+ CF C+ C++ L GD F +++ + CR Sbjct: 110 FSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHF 169 Query: 144 GLLLE---------------RAAAGSPRSPG-PLPGARGLHLP----------------- 170 LL+ AAA + +S G GA L LP Sbjct: 170 EALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRK 229 Query: 171 DAGSGRQPAL----------------RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANP 214 G G A R + ++KT R+RT QL T+++ +A N Sbjct: 230 SPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINH 289 Query: 215 RPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTP 274 PDA +QL + TGL+ RV++VWFQN R K ++++L ++ S +LQ TGTP Sbjct: 290 NPDAKDLKQLAQKTGLTKRVLQVWFQNARAK-FRRNLLRQENTGVDKSTDAALQ--TGTP 346 >gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] Length = 372 Score = 177 bits (448), Expect = 2e-44 Identities = 116/337 (34%), Positives = 172/337 (51%), Gaps = 22/337 (6%) Query: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDY 81 P A+C GC I D+F++RV+ + WH CL+CA C Q L T +C+ RD K YCK+DY Sbjct: 28 PHPAVCEGCQRPISDRFLMRVN-ESSWHEECLQCAACQQAL--TTSCYFRDRKLYCKQDY 84 Query: 82 VRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRA 141 +LF KC+ C + ++ VMRA + VYH+ CF C VC RQL GDEF L+E +LLC+ Sbjct: 85 QQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKG 144 Query: 142 DHGLLLERAAAGSPRSPGPLPG--ARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLN 199 D+ + ++ SP + G P G G Q K + R RT+L Sbjct: 145 DYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILT 204 Query: 200 EKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQ 259 +Q + + + +P ++E L TGLS RV++VWFQN+R K KK + +Q Q+Q Sbjct: 205 TQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQ 264 Query: 260 QHSDKTSLQGLTG---------TPLVAGSP--IRHENAVQGSAVEVQTYQPPWKALSEFA 308 Q+S + + L+ TPL + E + GS+ Q P + + Sbjct: 265 QNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDS 324 Query: 309 LQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQL 345 + D+D L S S+ LG+ SDV SL +++ Sbjct: 325 IFHDIDSDT--SLTSLSDC-FLGS---SDVGSLQARV 355 >gi|28893581 LIM homeobox transcription factor 1, alpha isoform a [Homo sapiens] Length = 382 Score = 175 bits (443), Expect = 6e-44 Identities = 99/256 (38%), Positives = 142/256 (55%), Gaps = 12/256 (4%) Query: 25 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRL 84 ++C GC I D+F+LR++ D WH C++CA C + L+ TC F RD K YCK DY +L Sbjct: 33 SVCEGCQRVILDRFLLRLN-DSFWHEQCVQCASCKEPLETTC--FYRDKKLYCKYDYEKL 89 Query: 85 FGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHG 144 F +KC C + ++ VMRA+ SVYH+ CF C VC RQL GDEF L+E +LLC+ D+ Sbjct: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149 Query: 145 LLLERAAAGSPRS--PGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQ 202 E + SP + G L G+G+ A HK+ + R RT+L +Q Sbjct: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPK---RPRTILTTQQ 206 Query: 203 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHS 262 + + + +P ++E L TGLS RV++VWFQN+R K KK + + QQQQ Sbjct: 207 RRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK----LARRQQQQQQ 262 Query: 263 DKTSLQGLTGTPLVAG 278 D+ + Q L+ G Sbjct: 263 DQQNTQRLSSAQTNGG 278 >gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] Length = 397 Score = 164 bits (415), Expect = 1e-40 Identities = 115/342 (33%), Positives = 161/342 (47%), Gaps = 61/342 (17%) Query: 26 MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLF 85 +C GC I D+FIL+ D WH+ CLKC++C L E C F R YCK D+ + F Sbjct: 30 LCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDDFFKRF 86 Query: 86 GIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLRE-HELLCRADHG 144 G KCA CQ+G + +V RA+D VYH+ CF C VC RQL GDEF L E L+C+AD+ Sbjct: 87 GTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146 Query: 145 LLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLH 204 +R A + + P RT + KQL Sbjct: 147 TAKQREAEATAKRP------------------------------------RTTITAKQLE 170 Query: 205 TLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK-KSILMKQLQQQQHSD 263 TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+ K +Q Q + Sbjct: 171 TLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRN 230 Query: 264 KTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEF----ALQSDLDQPAFQ 319 +G GS ++ +G + + P +L+E L L +P Q Sbjct: 231 MKRSRG--------GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPT-Q 281 Query: 320 QLVSFSESGSLGNSS----GSDVTSLSSQL-PDTPNSMVPSP 356 L SG+LGN S G +L P +P + PSP Sbjct: 282 AL--GRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 321 >gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] Length = 402 Score = 164 bits (415), Expect = 1e-40 Identities = 115/342 (33%), Positives = 161/342 (47%), Gaps = 61/342 (17%) Query: 26 MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLF 85 +C GC I D+FIL+ D WH+ CLKC++C L E C F R YCK D+ + F Sbjct: 35 LCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDDFFKRF 91 Query: 86 GIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLRE-HELLCRADHG 144 G KCA CQ+G + +V RA+D VYH+ CF C VC RQL GDEF L E L+C+AD+ Sbjct: 92 GTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151 Query: 145 LLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLH 204 +R A + + P RT + KQL Sbjct: 152 TAKQREAEATAKRP------------------------------------RTTITAKQLE 175 Query: 205 TLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK-KSILMKQLQQQQHSD 263 TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+ K +Q Q + Sbjct: 176 TLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRN 235 Query: 264 KTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEF----ALQSDLDQPAFQ 319 +G GS ++ +G + + P +L+E L L +P Q Sbjct: 236 MKRSRG--------GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPT-Q 286 Query: 320 QLVSFSESGSLGNSS----GSDVTSLSSQL-PDTPNSMVPSP 356 L SG+LGN S G +L P +P + PSP Sbjct: 287 AL--GRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 326 >gi|30410785 LIM homeobox protein 1 [Homo sapiens] Length = 406 Score = 164 bits (414), Expect = 1e-40 Identities = 96/247 (38%), Positives = 131/247 (53%), Gaps = 26/247 (10%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFG 86 C GC I D+F+L V D WH C++C EC L E C F R+GK YCK D+ R FG Sbjct: 4 CAGCKRPILDRFLLNVL-DRAWHVKCVQCCECKCNLTEKC--FSREGKLYCKNDFFRCFG 60 Query: 87 IKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDE-FSLREHELLCRADH-- 143 KCA C G S SDLV RAR V+H+ CF C +C++QL G+E + + E++ +C+ D+ Sbjct: 61 TKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLS 120 Query: 144 ------GLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTE-------- 189 L A GS P P ++ DA + E Sbjct: 121 NSSVAKENSLHSATTGS--DPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGA 178 Query: 190 KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKK 249 K RT + KQL TL+ +AA P+P ++EQL + TGL+ RVI+VWFQN+R K+++ Sbjct: 179 KRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR- 237 Query: 250 SILMKQL 256 MKQL Sbjct: 238 ---MKQL 241 >gi|11641283 LIM homeobox protein 5 [Homo sapiens] Length = 402 Score = 161 bits (408), Expect = 7e-40 Identities = 95/252 (37%), Positives = 132/252 (52%), Gaps = 37/252 (14%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFG 86 C GC I D+F+L V D WH C++C EC L E C F R+GK YCK D+ R FG Sbjct: 5 CAGCERPILDRFLLNVL-DRAWHIKCVQCCECKTNLSEKC--FSREGKLYCKNDFFRRFG 61 Query: 87 IKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDE-FSLREHELLCRADHGL 145 KCA C G S SDLV +AR V+H+ CF C VC++QL G+E + + E++ +C+ D+ Sbjct: 62 TKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDY-- 119 Query: 146 LLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTR------------ 193 + S G L Q AL+ K+T+ +T Sbjct: 120 -----LSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDD-PKETDNSTSSDKETANNENEE 173 Query: 194 ---------VRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRC 244 RT + KQL TL+ +AA P+P ++EQL + TGL+ RVI+VWFQN+R Sbjct: 174 QNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRS 233 Query: 245 KDKKKSILMKQL 256 K+++ MKQL Sbjct: 234 KERR----MKQL 241 >gi|15375314 LIM homeobox protein 4 [Homo sapiens] Length = 390 Score = 160 bits (405), Expect = 2e-39 Identities = 88/223 (39%), Positives = 117/223 (52%), Gaps = 39/223 (17%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFG 86 C GC I D+FIL+V D WH++CLKCA+C L + C F R G YCK D+ + FG Sbjct: 30 CAGCNQHILDKFILKVL-DRHWHSSCLKCADCQMQLADRC--FSRAGSVYCKEDFFKRFG 86 Query: 87 IKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREH-ELLCRADHGL 145 KC CQ G + +V +A+D VYH+ CF C +C+RQL GDEF L E L+C+ D+ Sbjct: 87 TKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY-- 144 Query: 146 LLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHT 205 E A G A RP RT + KQL T Sbjct: 145 --ETAKQNDDSEAG-------------------AKRP------------RTTITAKQLET 171 Query: 206 LRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248 L+ Y +P+P ++EQL TGL RV++VWFQN+R K+K+ Sbjct: 172 LKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214 >gi|50083287 LIM homeobox 8 [Homo sapiens] Length = 356 Score = 159 bits (401), Expect = 5e-39 Identities = 85/236 (36%), Positives = 125/236 (52%), Gaps = 14/236 (5%) Query: 13 AMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRD 72 +M S PG +C CG +I D+++L+V+ DL WH CL C+ C L +C+++D Sbjct: 61 SMASGSGCPPGKCVCNSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKD 119 Query: 73 GKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSL 132 +CK DY R +G +C++C S+D V RA+ +VYH+ CF C C RQL G+EF+L Sbjct: 120 KDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFAL 179 Query: 133 REHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTT 192 E ++LCR + +L+ + G+ + A Q P K Sbjct: 180 VEEKVLCRVHYDCMLDNLKR-------EVENGNGISVEGALLTEQDVNHPKPAK------ 226 Query: 193 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248 R RT QL ++ +A + PDA ++L E TGLS RVI+VWFQN R + KK Sbjct: 227 RARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282 >gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] Length = 377 Score = 158 bits (399), Expect = 8e-39 Identities = 83/226 (36%), Positives = 124/226 (54%), Gaps = 15/226 (6%) Query: 23 GTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYV 82 G +C CG +I D+++L+V+ +L WH CL+C+ C L + +C++++ + +CK DY Sbjct: 95 GKNICSSCGLEILDRYLLKVN-NLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYF 153 Query: 83 RLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRAD 142 FG KCA+C +SD V RAR + YH+ CF C C RQL G+EF L E ++LCR Sbjct: 154 SRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIH 213 Query: 143 HGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQ 202 + ++E + GL L A Q + Q + R RT +Q Sbjct: 214 YDTMIENLKRAA-------ENGNGLTLEGAVPSEQDS-------QPKPAKRARTSFTAEQ 259 Query: 203 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248 L ++ +A + PDA ++L +MTGLS RVI+VWFQN R + KK Sbjct: 260 LQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305 >gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] Length = 392 Score = 158 bits (399), Expect = 8e-39 Identities = 83/226 (36%), Positives = 124/226 (54%), Gaps = 15/226 (6%) Query: 23 GTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYV 82 G +C CG +I D+++L+V+ +L WH CL+C+ C L + +C++++ + +CK DY Sbjct: 95 GKNICSSCGLEILDRYLLKVN-NLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYF 153 Query: 83 RLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRAD 142 FG KCA+C +SD V RAR + YH+ CF C C RQL G+EF L E ++LCR Sbjct: 154 SRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIH 213 Query: 143 HGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQ 202 + ++E + GL L A Q + Q + R RT +Q Sbjct: 214 YDTMIENLKRAA-------ENGNGLTLEGAVPSEQDS-------QPKPAKRARTSFTAEQ 259 Query: 203 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248 L ++ +A + PDA ++L +MTGLS RVI+VWFQN R + KK Sbjct: 260 LQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305 >gi|5803072 LIM domain only 4 [Homo sapiens] Length = 165 Score = 112 bits (281), Expect = 4e-25 Identities = 61/157 (38%), Positives = 83/157 (52%), Gaps = 10/157 (6%) Query: 15 GDHSKKKPGTA------MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCT- 67 G S+ P TA C GCG +I D+F+L + D WH+ CLKC+ C L + T Sbjct: 5 GSSSQPPPVTAGSLSWKRCAGCGGKIADRFLL-YAMDSYWHSRCLKCSCCQAQLGDIGTS 63 Query: 68 CFVRDGKTYCKRDYVRLFGIK--CAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLL 125 C+ + G C+ DY+RLFG C+ C +S+LVMRA+ +VYH++CF CS C +L+ Sbjct: 64 CYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLV 123 Query: 126 PGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLP 162 PGD F L C D L S +S LP Sbjct: 124 PGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLP 160 >gi|21361802 LIM domain only 3 [Homo sapiens] Length = 145 Score = 107 bits (267), Expect = 2e-23 Identities = 51/127 (40%), Positives = 79/127 (62%), Gaps = 6/127 (4%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDET-CTCFVRDGKTYCKRDYVRLF 85 C GC +I D+++L+ D WH CLKCA C L E T + + C+RDY+RLF Sbjct: 13 CAGCNRKIKDRYLLKAL-DKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLF 71 Query: 86 GI--KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADH 143 G+ CA C + ++VMRA+D+VYH++CF C +C+++ GD+F L+ + +LC+ D+ Sbjct: 72 GVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDY 131 Query: 144 --GLLLE 148 GL+ E Sbjct: 132 EEGLMKE 138 >gi|47778935 LIM domain only 3 [Homo sapiens] Length = 145 Score = 107 bits (267), Expect = 2e-23 Identities = 51/127 (40%), Positives = 79/127 (62%), Gaps = 6/127 (4%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDET-CTCFVRDGKTYCKRDYVRLF 85 C GC +I D+++L+ D WH CLKCA C L E T + + C+RDY+RLF Sbjct: 13 CAGCNRKIKDRYLLKAL-DKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLF 71 Query: 86 GI--KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADH 143 G+ CA C + ++VMRA+D+VYH++CF C +C+++ GD+F L+ + +LC+ D+ Sbjct: 72 GVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDY 131 Query: 144 --GLLLE 148 GL+ E Sbjct: 132 EEGLMKE 138 >gi|4505005 LIM domain only 1 [Homo sapiens] Length = 156 Score = 105 bits (263), Expect = 5e-23 Identities = 49/120 (40%), Positives = 74/120 (61%), Gaps = 4/120 (3%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDET-CTCFVRDGKTYCKRDYVRLF 85 C GC +I D+++L+ D WH CLKCA C L E T + + C+RDY+RLF Sbjct: 24 CAGCNRKIKDRYLLKAL-DKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLF 82 Query: 86 GI--KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADH 143 G CA C + ++VMRARD+VYH++CF C +C+++ GD+F L+ + +LC+ D+ Sbjct: 83 GTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDY 142 >gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] Length = 158 Score = 92.4 bits (228), Expect = 5e-19 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 4/124 (3%) Query: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCT-CFVRDGKTYCKRD 80 P C GC I D++ L+ D WH CL C C L E + + G+ C+RD Sbjct: 25 PSLLTCGGCQQNIGDRYFLKAI-DQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRD 83 Query: 81 YVRLFGIK--CAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELL 138 Y+RLFG CA C + ++ MR +D VYH+ECF+C+ C + GD + L +++ Sbjct: 84 YLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIV 143 Query: 139 CRAD 142 C D Sbjct: 144 CEQD 147 >gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] Length = 158 Score = 92.4 bits (228), Expect = 5e-19 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 4/124 (3%) Query: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCT-CFVRDGKTYCKRD 80 P C GC I D++ L+ D WH CL C C L E + + G+ C+RD Sbjct: 25 PSLLTCGGCQQNIGDRYFLKAI-DQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRD 83 Query: 81 YVRLFGIK--CAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELL 138 Y+RLFG CA C + ++ MR +D VYH+ECF+C+ C + GD + L +++ Sbjct: 84 YLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIV 143 Query: 139 CRAD 142 C D Sbjct: 144 CEQD 147 >gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] Length = 227 Score = 92.4 bits (228), Expect = 5e-19 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 4/124 (3%) Query: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCT-CFVRDGKTYCKRD 80 P C GC I D++ L+ D WH CL C C L E + + G+ C+RD Sbjct: 94 PSLLTCGGCQQNIGDRYFLKAI-DQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRD 152 Query: 81 YVRLFGIK--CAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELL 138 Y+RLFG CA C + ++ MR +D VYH+ECF+C+ C + GD + L +++ Sbjct: 153 YLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIV 212 Query: 139 CRAD 142 C D Sbjct: 213 CEQD 216 >gi|4505001 LIM domain kinase 1 [Homo sapiens] Length = 647 Score = 81.3 bits (199), Expect = 1e-15 Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 15/159 (9%) Query: 14 MGDHSKKKPGTAMCVGCGSQIHD-QFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRD 72 MG+ + P +C CG +I+D Q++ ++ D WHA C +C +CS L + +D Sbjct: 15 MGEEGSELP---VCASCGQRIYDGQYLQALNAD--WHADCFRCCDCSASLSHQY--YEKD 67 Query: 73 GKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSL 132 G+ +CK+DY +G C C + LVM A + YH ECF C C + GD ++L Sbjct: 68 GQLFCKKDYWARYGESCHGCSEQITKG-LVMVAGELKYHPECFICLTCGTFIGDGDTYTL 126 Query: 133 REH-ELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP 170 EH +L C + +P LP + G HLP Sbjct: 127 VEHSKLYCGHCY-----YQTVVTPVIEQILPDSPGSHLP 160 >gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] Length = 746 Score = 80.9 bits (198), Expect = 2e-15 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Query: 14 MGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDG 73 M K+ ++ C GCG I + L ++ D +WH C KC C + L T +DG Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQAL-LALDKQWHLGCFKCKSCGKVL--TGEYISKDG 209 Query: 74 KTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLR 133 YC++DY LFG+KC C + V+ A D YH C RCS C++ G+E L+ Sbjct: 210 APYCEKDYQGLFGVKCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQ 267 Score = 63.9 bits (154), Expect = 2e-10 Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Query: 17 HSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTY 76 H +KP C CG + +LRV +H C C C L + F+++G+ Sbjct: 30 HPSEKP-VIHCHKCGEPCKGE-VLRVQTK-HFHIKCFTCKVCGCDLAQG-GFFIKNGEYL 85 Query: 77 CKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHE 136 C DY R++G +C C G V+ A YH CF C++C R PGD + + Sbjct: 86 CTLDYQRMYGTRCHGC--GEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRD 143 Query: 137 LLCR 140 LC+ Sbjct: 144 CLCQ 147 >gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] Length = 718 Score = 80.9 bits (198), Expect = 2e-15 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Query: 14 MGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDG 73 M K+ ++ C GCG I + L ++ D +WH C KC C + L T +DG Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQAL-LALDKQWHLGCFKCKSCGKVL--TGEYISKDG 209 Query: 74 KTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLR 133 YC++DY LFG+KC C + V+ A D YH C RCS C++ G+E L+ Sbjct: 210 APYCEKDYQGLFGVKCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQ 267 Score = 63.9 bits (154), Expect = 2e-10 Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Query: 17 HSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTY 76 H +KP C CG + +LRV +H C C C L + F+++G+ Sbjct: 30 HPSEKP-VIHCHKCGEPCKGE-VLRVQTK-HFHIKCFTCKVCGCDLAQG-GFFIKNGEYL 85 Query: 77 CKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHE 136 C DY R++G +C C G V+ A YH CF C++C R PGD + + Sbjct: 86 CTLDYQRMYGTRCHGC--GEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRD 143 Query: 137 LLCR 140 LC+ Sbjct: 144 CLCQ 147 >gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] Length = 778 Score = 80.9 bits (198), Expect = 2e-15 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Query: 14 MGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDG 73 M K+ ++ C GCG I + L ++ D +WH C KC C + L T +DG Sbjct: 213 MSSSPKETTFSSNCAGCGRDIKNGQAL-LALDKQWHLGCFKCKSCGKVL--TGEYISKDG 269 Query: 74 KTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLR 133 YC++DY LFG+KC C + V+ A D YH C RCS C++ G+E L+ Sbjct: 270 APYCEKDYQGLFGVKCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQ 327 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 8/134 (5%) Query: 9 PFLGAMGD--HSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETC 66 PF+ D H +KP C CG + +LRV +H C C C L + Sbjct: 80 PFVAHPQDPHHPSEKP-VIHCHKCGEPCKGE-VLRVQTK-HFHIKCFTCKVCGCDLAQG- 135 Query: 67 TCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLP 126 F+++G+ C DY R++G +C C G V+ A YH CF C++C R P Sbjct: 136 GFFIKNGEYLCTLDYQRMYGTRCHGC--GEFVEGEVVTALGKTYHPNCFACTICKRPFPP 193 Query: 127 GDEFSLREHELLCR 140 GD + + LC+ Sbjct: 194 GDRVTFNGRDCLCQ 207 >gi|7662330 actin binding LIM protein family, member 3 [Homo sapiens] Length = 683 Score = 75.1 bits (183), Expect = 9e-14 Identities = 52/150 (34%), Positives = 68/150 (45%), Gaps = 14/150 (9%) Query: 23 GTAMCVGCGSQI-HDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDY 81 G + C GC +I H Q +L + D +WH +C KC CS L T +DG YC+ DY Sbjct: 147 GPSHCAGCKEEIKHGQSLLAL--DKQWHVSCFKCQTCSVIL--TGEYISKDGVPYCESDY 202 Query: 82 VRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHEL---L 138 FGIKC C S V+ A YH C RC C + G+E L E+ + Sbjct: 203 HAQFGIKCETCDRYISGR--VLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPI 260 Query: 139 C----RADHGLLLERAAAGSPRSPGPLPGA 164 C RA+ L R + S PG G+ Sbjct: 261 CKQAARAEKKLKHRRTSETSISPPGSSIGS 290 Score = 53.5 bits (127), Expect = 3e-07 Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 5/114 (4%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFG 86 C CG + ++RV + +H C C C L ++ F ++ + C +DY +L+G Sbjct: 23 CYRCGDTCKGE-VVRVHNN-HFHIRCFTCQVCGCGLAQS-GFFFKNQEYICTQDYQQLYG 79 Query: 87 IKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCR 140 +C C+ + V+ A YH +CF CS+C + GD+ + E +C+ Sbjct: 80 TRCDSCRDFITGE--VISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQ 131 >gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens] Length = 638 Score = 72.4 bits (176), Expect = 6e-13 Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 4/112 (3%) Query: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFG 86 C GCG I I + + WH +C +C+EC L T + +DGK YC +DY FG Sbjct: 12 CPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSL--TNWYYEKDGKLYCPKDYWGKFG 69 Query: 87 IKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELL 138 C C + + +V A + YH ECF C C + GD ++L +H L Sbjct: 70 EFCHGCSLLMTGPFMV--AGEFKYHPECFACMSCKVIIEDGDAYALVQHATL 119 Score = 29.6 bits (65), Expect = 4.4 Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 2/56 (3%) Query: 88 KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADH 143 +C C + S + R + +H CFRCS C L + + ++ +L C D+ Sbjct: 11 RCPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSLT--NWYYEKDGKLYCPKDY 64 >gi|194272207 actin binding LIM protein family, member 2 isoform 7 [Homo sapiens] Length = 470 Score = 71.2 bits (173), Expect = 1e-12 Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Query: 13 AMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRD 72 ++G + G C GCG++I + L V+ D WH C KC C + L+ +D Sbjct: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQAL-VALDKHWHLGCFKCKSCGKLLN--AEYISKD 195 Query: 73 GKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSL 132 G YC+ DY FGI+C C+ + V+ A + YH C C C + G+E L Sbjct: 196 GLPYCEADYHAKFGIRCDSCEKYITGR--VLEAGEKHYHPSCALCVRCGQMFAEGEEMYL 253 Query: 133 R 133 + Sbjct: 254 Q 254 Score = 69.3 bits (168), Expect = 5e-12 Identities = 43/123 (34%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Query: 19 KKKPGTA-MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYC 77 +K P TA +C CG+ + +LRV D +H C C C L E FVR G+ C Sbjct: 15 EKSPSTAILCNTCGNVCKGE-VLRVQ-DKYFHIKCFVCKACGCDLAEG-GFFVRQGEYIC 71 Query: 78 KRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHEL 137 DY RL+G +C C V+ A YH +CF C+VC PGD + E Sbjct: 72 TLDYQRLYGTRCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKEC 129 Query: 138 LCR 140 +C+ Sbjct: 130 MCQ 132 Score = 28.9 bits (63), Expect = 7.5 Identities = 14/46 (30%), Positives = 19/46 (41%) Query: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCT 67 P A+CV CG + + + WH AC + A ET T Sbjct: 233 PSCALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRT 278 >gi|153792514 actin binding LIM protein family, member 2 isoform 6 [Homo sapiens] Length = 521 Score = 71.2 bits (173), Expect = 1e-12 Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Query: 13 AMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRD 72 ++G + G C GCG++I + L V+ D WH C KC C + L+ +D Sbjct: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQAL-VALDKHWHLGCFKCKSCGKLLN--AEYISKD 195 Query: 73 GKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSL 132 G YC+ DY FGI+C C+ + V+ A + YH C C C + G+E L Sbjct: 196 GLPYCEADYHAKFGIRCDSCEKYITGR--VLEAGEKHYHPSCALCVRCGQMFAEGEEMYL 253 Query: 133 R 133 + Sbjct: 254 Q 254 Score = 69.3 bits (168), Expect = 5e-12 Identities = 43/123 (34%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Query: 19 KKKPGTA-MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYC 77 +K P TA +C CG+ + +LRV D +H C C C L E FVR G+ C Sbjct: 15 EKSPSTAILCNTCGNVCKGE-VLRVQ-DKYFHIKCFVCKACGCDLAEG-GFFVRQGEYIC 71 Query: 78 KRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHEL 137 DY RL+G +C C V+ A YH +CF C+VC PGD + E Sbjct: 72 TLDYQRLYGTRCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKEC 129 Query: 138 LCR 140 +C+ Sbjct: 130 MCQ 132 Score = 28.9 bits (63), Expect = 7.5 Identities = 14/46 (30%), Positives = 19/46 (41%) Query: 22 PGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCT 67 P A+CV CG + + + WH AC + A ET T Sbjct: 233 PSCALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRT 278 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.133 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,776,834 Number of Sequences: 37866 Number of extensions: 810719 Number of successful extensions: 4151 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 334 Number of HSP's successfully gapped in prelim test: 131 Number of HSP's that attempted gapping in prelim test: 3243 Number of HSP's gapped (non-prelim): 729 length of query: 359 length of database: 18,247,518 effective HSP length: 103 effective length of query: 256 effective length of database: 14,347,320 effective search space: 3672913920 effective search space used: 3672913920 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.